gene_id	baseMean	log2FoldChange	lfcSE	stat	pvalue	padj	PSC.0228	PSC.0187	PSC.0188	PSC.0174	PSC.0190	PSC.0231	PSC.0230	PSC.0219	PSC.0177	PSC.0186	PSC.0209	PSC.0203	V2	uniprot_accession	gene_name	V5	V6	V7	V8	V9	V10	V11	V12	V13	V14	Entry	Reviewed	Entry.Name	Protein.names	Gene.Names	Organism	Length	Gene.Ontology.IDs
g20093	13383.63629	1.080012474	0.215565181	5.010143432	5.44E-07	6.80E-06	14964	15915	11759	15594	14815	16252	9702	8378	10597	11785	8483	11579	sp	Q02543	RL18A_HUMAN	70.455	176	51	1	1	525	1	176	5.35E-86	253	Q02543	reviewed	RL18A_HUMAN	Large ribosomal subunit protein eL20 (60S ribosomal protein L18a)	RPL18A	Homo sapiens (Human)	176	GO:0002181; GO:0003723; GO:0003735; GO:0005737; GO:0005829; GO:0006412; GO:0016020; GO:0022625; GO:0022626
g11895	133.1345151	-1.071374392	0.395207813	-2.710913999	0.006709803	0.022547131	94	101	63	97	19	86	230	213	215	367	77	225	sp	Q8CBC7	TRM7_MOUSE	72.945	292	75	1	1	876	1	288	2.13E-143	410	Q8CBC7	reviewed	TRM7_MOUSE	tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase (EC 2.1.1.205) (2'-O-ribose RNA methyltransferase TRM7 homolog) (Protein ftsJ homolog 1)	Ftsj1	Mus musculus (Mouse)	324	GO:0002130; GO:0002181; GO:0005634; GO:0005737; GO:0005829; GO:0008175; GO:0016423; GO:0022008; GO:0030488; GO:0106339; GO:0106340; GO:1904047
g509	7383.706421	1.219442811	0.440961637	2.76541701	0.005685007	0.019749364	9693	9717	6256	8211	8065	9274	6514	4681	5713	7023	800	7485	sp	P63221	RS21_PIG	73.494	83	22	0	1	249	1	83	1.54E-40	131	P63221	reviewed	RS21_PIG	Small ribosomal subunit protein eS21 (40S ribosomal protein S21)	RPS21	Sus scrofa (Pig)	83	GO:0000447; GO:0000461; GO:0002181; GO:0003735; GO:0022627; GO:0043022; GO:0098556
g16638	3315.794203	0.640159227	0.195285844	3.278062637	0.001045222	0.004796019	3194	4752	3151	3266	2539	3570	3421	2861	2952	3667	2233	3624	sp	P27659	RL3_MOUSE	87.013	77	10	0	1	231	1	77	3.56E-42	144	P27659	reviewed	RL3_MOUSE	Large ribosomal subunit protein uL3 (60S ribosomal protein L3) (J1 protein)	Rpl3	Mus musculus (Mouse)	403	GO:0002181; GO:0003723; GO:0003735; GO:0005730; GO:0005737; GO:0005829; GO:0005840; GO:0006412; GO:0008097; GO:0022625; GO:0045202; GO:0071353
g6297	15824.88504	1.18614926	0.287485879	4.125939208	3.69E-05	0.000273543	19769	21264	12747	17681	18702	17854	13191	10797	11527	14468	5665	13775	sp	Q8JGR4	RL24_DANRE	63.057	157	55	1	1	462	1	157	6.33E-50	160	Q8JGR4	reviewed	RL24_DANRE	Large ribosomal subunit protein eL24 (60S ribosomal protein L24)	rpl24	Danio rerio (Zebrafish) (Brachydanio rerio)	157	GO:0002181; GO:0003729; GO:0003735; GO:0022625; GO:0043009
g9064	9806.792982	0.746088632	0.186503427	4.000401733	6.32E-05	0.000431277	10128	12246	8126	9337	8506	12626	9033	5685	7757	11551	8291	10603	sp	Q8UW19	RL36_HYDHA	65.278	72	21	1	1	204	1	72	1.90E-14	66.6	Q8UW19	reviewed	RL36_HYDHA	Large ribosomal subunit protein eL36 (60S ribosomal protein L36)	RPL36	Hydrophis hardwickii (Hardwick's spine-bellied seasnake) (Lapemis hardwickii)	105	GO:0002181; GO:0003735; GO:0022625
g13448	7454.48835	0.79925836	0.165687329	4.823895483	1.41E-06	1.58E-05	8426	9458	6721	7394	6785	8492	7164	5224	5955	6928	6689	7112	sp	G1SQH0	RL26_RABIT	78.014	141	30	1	1	423	1	140	2.49E-43	142	G1SQH0	reviewed	RL26_RABIT	Large ribosomal subunit protein uL24 (60S ribosomal protein L26)	RPL26	Oryctolagus cuniculus (Rabbit)	145	GO:0002181; GO:0003735; GO:0005654; GO:0005730; GO:0006364; GO:0006977; GO:0022625; GO:0042273; GO:0045202; GO:0045727; GO:0048027; GO:0071480; GO:1902164; GO:1902167; GO:1904803
g4288	8430.540375	0.921241632	0.228371327	4.033963648	5.48E-05	0.000380873	9298	9711	5784	10188	9337	9636	7148	4875	6755	7371	7997	6750	sp	P62861	RS30_HUMAN	59.398	133	54	0	1	399	1	133	9.18E-47	150	P62861	reviewed	RS30_HUMAN	Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein (FAU ubiquitin like and ribosomal protein S30 fusion) [Cleaved into: Ubiquitin-like protein FUBI; Small ribosomal subunit protein eS30 (40S ribosomal protein S30)]	FAU	Homo sapiens (Human)	133	GO:0002181; GO:0002227; GO:0003723; GO:0003735; GO:0005615; GO:0005654; GO:0005737; GO:0005829; GO:0006412; GO:0015935; GO:0019731; GO:0022626; GO:0022627; GO:0050830; GO:0061844
g21139	2696.493872	0.784580917	0.218307774	3.593921105	0.000325739	0.001776026	2724	4061	1986	2862	2420	2862	2348	1689	1946	2819	2415	3098	sp	A0A1D8PF57	RL29_CANAL	71.739	46	13	0	1	138	1	46	6.02E-17	71.6	A0A1D8PF57	reviewed	RL29_CANAL	Large ribosomal subunit protein eL29 (60S ribosomal protein L29)	RPL29 orf19.2310.1 CAALFM_C111040WA	Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)	63	GO:0002181; GO:0003735; GO:0022625
g17634	14990.59955	0.856824075	0.235823569	3.633326729	0.00027979	0.001562012	16877	23222	13087	12362	14882	16007	18935	10398	11977	15558	9082	12865	sp	P38983	RSSA_RAT	64.164	293	89	5	1	879	1	277	3.62E-130	375	P38983	reviewed	RSSA_RAT	Small ribosomal subunit protein uS2 (37 kDa laminin receptor precursor) (37LRP) (37/67 kDa laminin receptor) (LRP/LR) (40S ribosomal protein SA) (67 kDa laminin receptor) (67LR) (Laminin receptor 1) (LamR) (Laminin-binding protein precursor p40) (LBP/p40)	Rpsa Lamr1	Rattus norvegicus (Rat)	295	GO:0000028; GO:0002181; GO:0003677; GO:0003735; GO:0005055; GO:0005198; GO:0005604; GO:0005634; GO:0005737; GO:0005886; GO:0015935; GO:0022626; GO:0022627; GO:0030855; GO:0043022; GO:0043025; GO:0043236; GO:0045202; GO:0062023; GO:0098609; GO:0098978; GO:0140374
g16170	7227.855664	0.933500154	0.320418115	2.913381328	0.003575377	0.013435557	9271	10386	6794	6817	6195	7951	5492	3995	4557	4635	11999	5008	sp	P47955	RLA1_MOUSE	73.016	63	17	0	1	189	1	63	2.72E-26	97.1	P47955	reviewed	RLA1_MOUSE	Large ribosomal subunit protein P1 (60S acidic ribosomal protein P1)	Rplp1	Mus musculus (Mouse)	114	GO:0002181; GO:0003735; GO:0005737; GO:0005829; GO:0005840; GO:0006414; GO:0006417; GO:0022625; GO:0030295; GO:0043021; GO:0045202; GO:0098794
g19012	29487.34226	0.833164661	0.225300209	3.698019912	0.000217288	0.001257821	31660	36431	26593	25639	30250	36054	27585	20875	26967	30437	19651	26296	sp	G1SKF7	RL6_RABIT	59.375	256	97	2	10	756	36	291	1.59E-78	241	G1SKF7	reviewed	RL6_RABIT	Large ribosomal subunit protein eL6 (60S ribosomal protein L6)	RPL6	Oryctolagus cuniculus (Rabbit)	291	GO:0000027; GO:0002181; GO:0003723; GO:0003735; GO:0005791; GO:0022625
g22950	17935.18184	0.841338802	0.204785339	4.10839373	3.98E-05	0.000291668	17847	24741	16807	21795	15895	18239	16601	10932	16385	15100	16389	16253	sp	P05388	RLA0_HUMAN	73.091	275	74	0	1	825	1	275	2.37E-141	404	P05388	reviewed	RLA0_HUMAN	Large ribosomal subunit protein uL10 (60S acidic ribosomal protein P0) (60S ribosomal protein L10E)	RPLP0	Homo sapiens (Human)	317	GO:0000027; GO:0002181; GO:0003723; GO:0003735; GO:0005634; GO:0005737; GO:0005783; GO:0005829; GO:0005925; GO:0006412; GO:0014069; GO:0016020; GO:0022625; GO:0022626; GO:0036464; GO:0070062; GO:0070180; GO:0098794; GO:1990904
g18210	13485.69093	1.014776515	0.28585572	3.549960502	0.000385289	0.002045788	16170	19478	11623	13658	13283	15955	14561	9848	10453	13995	4502	12247	sp	P51410	RL9_MOUSE	67.188	192	61	1	1	570	1	192	2.53E-96	280	P51410	reviewed	RL9_MOUSE	Large ribosomal subunit protein uL6 (60S ribosomal protein L9)	Rpl9	Mus musculus (Mouse)	192	GO:0002181; GO:0003735; GO:0005737; GO:0005829; GO:0005840; GO:0006412; GO:0019843; GO:0022625; GO:0045202; GO:0098793; GO:0098794; GO:0140236; GO:0140242
g16934	21078.48811	0.754370807	0.183307098	4.115338763	3.87E-05	0.000284592	26627	24494	15560	20828	19413	25048	23146	14346	16765	22042	17463	19677	sp	O61231	RL10_DROME	80.282	213	42	0	1	639	1	213	4.13E-131	370	O61231	reviewed	RL10_DROME	Large ribosomal subunit protein uL16 (60S ribosomal protein L10) (QM protein homolog) (dQM)	RpL10 Qm CG17521	Drosophila melanogaster (Fruit fly)	218	GO:0000027; GO:0002181; GO:0003735; GO:0005737; GO:0022625; GO:0022626; GO:0043025
g1094	11298.20244	0.945641836	0.208868377	4.527453363	5.97E-06	5.65E-05	12290	16641	10762	10580	10870	12987	9360	7097	8937	12955	8195	9297	sp	Q9VXX8	RL371_DROME	81.818	88	16	0	1	264	1	88	3.61E-40	131	Q9VXX8	reviewed	RL371_DROME	Large ribosomal subunit protein eL37A (Probable 60S ribosomal protein L37-A) (Ribosomal protein L37-1)	RpL37-1 RpL37a CG9091	Drosophila melanogaster (Fruit fly)	93	GO:0002181; GO:0003723; GO:0003735; GO:0019843; GO:0022625; GO:0022626; GO:0046872
g17410	252.367808	-0.684555281	0.257984279	-2.653476731	0.007966726	0.025913252	144	231	284	154	105	90	772	457	328	305	275	249	sp	D2XV59	GTPB1_RAT	72.084	523	143	2	124	1686	102	623	0	692	D2XV59	reviewed	GTPB1_RAT	GTP-binding protein 1	Gtpbp1	Rattus norvegicus (Rat)	669	GO:0000049; GO:0000177; GO:0002181; GO:0003746; GO:0003924; GO:0005525; GO:0005829; GO:0006414; GO:0046039; GO:0061014; GO:1904678
g16116	4512.928363	1.003537602	0.25871899	3.878871062	0.000104942	0.000671678	5130	6295	4521	5347	4089	4941	4890	3484	3461	4153	1599	4433	sp	P18101	RL40_DROME	97.656	128	3	0	1	384	1	128	1.06E-89	258	P18101	reviewed	RL40_DROME	Ubiquitin-ribosomal protein eL40 fusion protein (CEP52) [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40 (60S ribosomal protein L40)]	RpL40 Ubi-f UBI-F52 CG2960	Drosophila melanogaster (Fruit fly)	128	GO:0002181; GO:0003735; GO:0005634; GO:0005829; GO:0006412; GO:0006511; GO:0016567; GO:0019941; GO:0022625; GO:0022627; GO:0031386; GO:0031625; GO:0036211
g22412	18868.89125	0.635442737	0.211510973	3.004301522	0.002661914	0.010543817	18497	21618	14990	20315	18057	19310	15553	14046	15300	16846	22667	19766	sp	P62914	RL11_RAT	86.932	176	23	0	16	543	3	178	6.42E-103	296	P62914	reviewed	RL11_RAT	Large ribosomal subunit protein uL5 (60S ribosomal protein L11)	Rpl11	Rattus norvegicus (Rat)	178	GO:0002181; GO:0003723; GO:0003735; GO:0005654; GO:0005730; GO:0005737; GO:0005840; GO:0006364; GO:0006412; GO:0006605; GO:0008097; GO:0010628; GO:0022625; GO:0022626; GO:0031625; GO:0032435; GO:0032991; GO:0034504; GO:0042273; GO:0042975; GO:0045202; GO:0050821; GO:0098793; GO:0098794; GO:0140236; GO:0140242; GO:1901796; GO:1901798; GO:1990948; GO:2000059; GO:2000435
g23112	14829.85381	0.965166213	0.256218787	3.766961143	0.000165247	0.000993552	17027	20748	13330	15417	14296	17241	15214	10956	12367	14829	5977	13834	sp	P36241	RL19_DROME	77.157	197	45	0	1	591	1	197	2.79E-86	256	P36241	reviewed	RL19_DROME	Large ribosomal subunit protein eL19 (60S ribosomal protein L19)	RpL19 M(2)60E CG2746	Drosophila melanogaster (Fruit fly)	203	GO:0002181; GO:0003723; GO:0003735; GO:0022625; GO:0022626
g6599	11852.52876	0.849109241	0.223325151	3.802120976	0.000143463	0.000881613	12029	14810	8595	11572	13297	13898	11071	7187	9137	11414	10653	10726	sp	P61314	RL15_RAT	81.373	204	38	0	1	612	1	204	1.79E-110	317	P61314	reviewed	RL15_RAT	Large ribosomal subunit protein eL15 (60S ribosomal protein L15)	Rpl15	Rattus norvegicus (Rat)	204	GO:0002181; GO:0003723; GO:0003735; GO:0005634; GO:0005737; GO:0022625; GO:0022626; GO:0031672; GO:0045202; GO:0045471
g10949	13044.80766	0.828374017	0.199367928	4.155001381	3.25E-05	0.000246708	13758	18621	10491	13576	12624	13784	12535	9115	9956	12450	12444	11040	sp	P62907	RL10A_RAT	79.07	215	45	0	4	648	3	217	4.18E-111	320	P62907	reviewed	RL10A_RAT	Large ribosomal subunit protein uL1 (60S ribosomal protein L10a)	Rpl10a	Rattus norvegicus (Rat)	217	GO:0002181; GO:0003723; GO:0003735; GO:0005737; GO:0006412; GO:0014069; GO:0022625; GO:0022626; GO:0045202; GO:0045471
g9309	10434.28719	0.814454896	0.211701057	3.847193339	0.000119479	0.000753541	11752	17154	9240	8677	8936	11429	10061	7550	7849	10078	9241	10069	sp	P24049	RL17_RAT	80.247	162	32	0	1	486	1	162	2.75E-97	282	P24049	reviewed	RL17_RAT	Large ribosomal subunit protein uL22 (60S ribosomal protein L17) (Amino acid starvation-induced protein) (ASI) (L23)	Rpl17	Rattus norvegicus (Rat)	184	GO:0002181; GO:0003735; GO:0005737; GO:0022625; GO:0022626; GO:0031672; GO:0034198; GO:0045202; GO:0070180; GO:1900087; GO:1990928
g20355	8071.577718	0.689010907	0.252280385	2.731131506	0.006311728	0.021431949	8456	8935	6821	8902	6931	9117	6777	4964	5896	6612	13069	6553	sp	Q86FP7	RS23_DERVA	93.662	142	9	0	10	435	2	143	1.56E-92	267	Q86FP7	reviewed	RS23_DERVA	Small ribosomal subunit protein uS12 (40S ribosomal protein S23)	RpS23	Dermacentor variabilis (American dog tick)	143	GO:0002181; GO:0003735; GO:0005791; GO:0022627
g20594	973.7628645	1.636652935	0.462629184	3.537720902	0.000403596	0.002132907	1707	633	833	1759	1330	910	610	280	653	305	1082	289	sp	Q6P799	SYSC_RAT	68.116	483	151	3	1	1446	1	481	0	681	Q6P799	reviewed	SYSC_RAT	"Serine--tRNA ligase, cytoplasmic (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)"	Sars1 Sars	Rattus norvegicus (Rat)	512	GO:0000049; GO:0000122; GO:0000978; GO:0001514; GO:0002181; GO:0004828; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006400; GO:0006434; GO:0016525; GO:0019899; GO:0042803; GO:0060090; GO:0098619; GO:1904046
g18183	6111.860919	1.020918266	0.212131437	4.812668408	1.49E-06	1.65E-05	7004	8036	5561	6574	6164	7353	5366	4138	4676	5886	3239	5710	sp	O09167	RL21_MOUSE	66.667	162	51	1	10	495	2	160	8.34E-67	203	O09167	reviewed	RL21_MOUSE	Large ribosomal subunit protein eL21 (60S ribosomal protein L21)	Rpl21	Mus musculus (Mouse)	160	GO:0002181; GO:0003735; GO:0005737; GO:0005783; GO:0005829; GO:0005840; GO:0022625; GO:0045202; GO:0098794
g13994	18666.49357	0.756089041	0.19606498	3.856318654	0.000115107	0.000730778	21755	22144	15444	16365	18086	22458	19256	13855	14483	17551	18969	15509	sp	P41116	RL8_XENLA	84.921	252	38	0	1	756	1	252	2.55E-160	447	P41116	reviewed	RL8_XENLA	Large ribosomal subunit protein uL2 (60S ribosomal protein L8)	rpl8	Xenopus laevis (African clawed frog)	257	GO:0002181; GO:0003735; GO:0019843; GO:0022625
g11209	10090.45142	1.122800813	0.213368965	5.262249884	1.42E-07	2.07E-06	11762	12993	9472	11178	10468	12764	8612	5836	8140	8423	5570	8830	sp	P27085	RS26_OCTVU	84.348	115	17	1	103	444	1	115	1.45E-53	168	P27085	reviewed	RS26_OCTVU	Small ribosomal subunit protein eS26 (40S ribosomal protein S26)	RPS26	Octopus vulgaris (Common octopus)	127	GO:0002181; GO:0003729; GO:0003735; GO:0005840; GO:0022627; GO:0098556
g17311	11841.92593	0.833852655	0.175370673	4.754801024	1.99E-06	2.14E-05	13507	14780	10315	13217	10843	13284	12502	9373	9931	10947	8118	10499	sp	Q90YV0	RL18_ICTPU	77.128	188	43	0	1	564	1	188	7.07E-100	289	Q90YV0	reviewed	RL18_ICTPU	Large ribosomal subunit protein eL18 (60S ribosomal protein L18)	rpl18	Ictalurus punctatus (Channel catfish) (Silurus punctatus)	188	GO:0002181; GO:0003735; GO:0005791; GO:0022625
g11942	44.3619048	-3.018905058	0.623461259	-4.842169446	1.28E-06	1.45E-05	10	15	20	0	2	11	156	130	38	152	72	48	sp	Q8CBC7	TRM7_MOUSE	72.945	292	75	1	1	876	1	288	3.29E-139	400	Q8CBC7	reviewed	TRM7_MOUSE	tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase (EC 2.1.1.205) (2'-O-ribose RNA methyltransferase TRM7 homolog) (Protein ftsJ homolog 1)	Ftsj1	Mus musculus (Mouse)	324	GO:0002130; GO:0002181; GO:0005634; GO:0005737; GO:0005829; GO:0008175; GO:0016423; GO:0022008; GO:0030488; GO:0106339; GO:0106340; GO:1904047
g14134	7670.156459	0.731213808	0.258503703	2.828639587	0.004674631	0.016832505	8585	10893	5954	5968	7146	8241	6448	4580	4620	7953	10371	8197	sp	P49180	RL35A_CAEEL	60	110	44	0	10	339	15	124	8.72E-47	149	P49180	reviewed	RL35A_CAEEL	Large ribosomal subunit protein eL33 (60S ribosomal protein L35a)	rpl-33 F10E7.7	Caenorhabditis elegans	124	GO:0002181; GO:0003735; GO:0022625; GO:0042273
g19475	786.8160768	2.172942532	0.338873005	6.412262121	1.43E-10	4.17E-09	1558	1176	670	1012	1250	622	381	302	415	293	310	332	sp	Q9H3F6	BACD3_HUMAN	71.483	263	68	4	88	873	28	284	2.79E-134	386	Q9H3F6	reviewed	BACD3_HUMAN	BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 (hBACURD3) (BTB/POZ domain-containing protein KCTD10) (Potassium channel tetramerization domain-containing protein 10)	KCTD10 ULR061 MSTP028	Homo sapiens (Human)	313	GO:0005112; GO:0005654; GO:0005829; GO:0006511; GO:0016567; GO:0031463; GO:0035024; GO:0042802; GO:0043161; GO:0051260
g14478	60.73188569	-2.481746684	0.331253649	-7.491982941	6.78E-14	3.55E-12	21	17	11	21	10	15	102	125	144	120	137	100	sp	P0C2W1	FBSP1_HUMAN	72.727	220	59	1	25	681	39	258	3.93E-115	334	P0C2W1	reviewed	FBSP1_HUMAN	F-box/SPRY domain-containing protein 1 (F-box only protein 45) (hFbxo45)	FBXO45 FBX45	Homo sapiens (Human)	286	GO:0001764; GO:0005576; GO:0005634; GO:0005737; GO:0006511; GO:0006974; GO:0014069; GO:0016567; GO:0019005; GO:0021799; GO:0021800; GO:0021957; GO:0021960; GO:0042734; GO:0042995; GO:0043161; GO:0045202; GO:0045211; GO:0060386; GO:0070936; GO:0098978; GO:0099523; GO:0099524; GO:1990756; GO:2000300
g21847	49.23760315	-1.330844417	0.4095966	-3.249158847	0.001157468	0.005255267	37	29	53	8	16	13	137	70	48	107	69	91	sp	Q5PQN1	HERC4_RAT	49.198	374	172	6	13	1131	3	359	1.72E-103	335	Q5PQN1	reviewed	HERC4_RAT	Probable E3 ubiquitin-protein ligase HERC4 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 4) (HECT-type E3 ubiquitin transferase HERC4)	Herc4	Rattus norvegicus (Rat)	1057	GO:0001650; GO:0005737; GO:0005829; GO:0006511; GO:0007283; GO:0016567; GO:0030154; GO:0045879; GO:0061630
g9753	1168.050089	0.90026103	0.310397711	2.90034687	0.003727499	0.013891211	1688	1093	1144	938	1463	1091	1776	752	697	1428	591	902	sp	Q6I6G8	HECW2_MOUSE	58.853	802	264	8	2803	5103	808	1578	0	840	Q6I6G8	reviewed	HECW2_MOUSE	"E3 ubiquitin-protein ligase HECW2 (EC 2.3.2.26) (HECT, C2 and WW domain-containing protein 2) (HECT-type E3 ubiquitin transferase HECW2) (NEDD4-like E3 ubiquitin-protein ligase 2)"	Hecw2 Kiaa1301 Nedl2	Mus musculus (Mouse)	1578	GO:0005737; GO:0006511; GO:0016567; GO:0030071; GO:0048814; GO:0061630; GO:0072686
g13596	29.35415368	4.046800824	1.14272458	3.541361494	0.000398068	0.0021091	32	114	106	5	0	63	2	9	4	0	0	7	sp	Q4G0X4	KCD21_HUMAN	56.757	111	44	1	1	333	1	107	1.08E-36	128	Q4G0X4	reviewed	KCD21_HUMAN	BTB/POZ domain-containing protein KCTD21 (KCASH2 protein) (Potassium channel tetramerization domain-containing protein 21)	KCTD21	Homo sapiens (Human)	260	GO:0006511; GO:0016567; GO:0042802; GO:0042826; GO:0045879; GO:0051260; GO:0097602
g13599	49.97825539	0.919499111	0.332158109	2.768257302	0.005635694	0.019609626	52	43	64	74	48	45	51	24	54	35	32	50	sp	Q3URF8	KCD21_MOUSE	55.263	114	50	1	13	351	2	115	4.63E-34	125	Q3URF8	reviewed	KCD21_MOUSE	BTB/POZ domain-containing protein KCTD21 (KCASH2 protein) (Potassium channel tetramerization domain-containing protein 21)	Kctd21	Mus musculus (Mouse)	260	GO:0006511; GO:0016567; GO:0042826; GO:0051260; GO:0097602
g17328	162.3532508	1.376022534	0.349425589	3.937955821	8.22E-05	0.00054393	220	159	155	155	224	219	125	84	111	97	52	168	sp	Q9HAU4	SMUF2_HUMAN	70.5	200	50	2	1	600	1	191	5.31E-96	300	Q9HAU4	reviewed	SMUF2_HUMAN	E3 ubiquitin-protein ligase SMURF2 (hSMURF2) (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase SMURF2) (SMAD ubiquitination regulatory factor 2) (SMAD-specific E3 ubiquitin-protein ligase 2)	SMURF2	Homo sapiens (Human)	748	GO:0000122; GO:0000151; GO:0004842; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0006511; GO:0016567; GO:0016607; GO:0017015; GO:0030512; GO:0030514; GO:0042802; GO:0043161; GO:0045121; GO:0045892; GO:0046332; GO:0060071; GO:0061630; GO:0090263; GO:1901165
g4809	221.6429406	-1.063798978	0.290648971	-3.660081694	0.000252135	0.001426533	165	158	249	90	40	106	663	312	235	475	296	276	sp	Q5ND34	WDR81_MOUSE	33.333	1047	592	22	1246	4323	55	1016	8.51E-144	494	Q5ND34	reviewed	WDR81_MOUSE	WD repeat-containing protein 81	Wdr81	Mus musculus (Mouse)	1934	GO:0000421; GO:0005739; GO:0005765; GO:0005829; GO:0006511; GO:0007005; GO:0010008; GO:0031901; GO:0031902; GO:0035014; GO:0035973; GO:0045022; GO:0050821; GO:0070530; GO:0141039
g13964	979.0957353	-1.66364409	0.248592426	-6.69225574	2.20E-11	7.39E-10	572	784	467	246	206	316	2959	2135	1251	2140	1019	1643	sp	P49407	ARRB1_HUMAN	57.045	440	145	12	187	1488	4	405	3.35E-151	441	P49407	reviewed	ARRB1_HUMAN	Beta-arrestin-1 (Arrestin beta-1) (Non-visual arrestin-2)	ARRB1 ARR1	Homo sapiens (Human)	418	GO:0000139; GO:0000785; GO:0001664; GO:0001934; GO:0002031; GO:0002092; GO:0003713; GO:0004857; GO:0005096; GO:0005159; GO:0005634; GO:0005654; GO:0005737; GO:0005765; GO:0005829; GO:0005886; GO:0005905; GO:0006357; GO:0006511; GO:0007165; GO:0007601; GO:0015031; GO:0016567; GO:0016604; GO:0030659; GO:0031143; GO:0031397; GO:0031410; GO:0031625; GO:0031701; GO:0032088; GO:0032715; GO:0032717; GO:0035025; GO:0043149; GO:0043161; GO:0045746; GO:0045944; GO:0070374; GO:1990763
g14365	2398.618788	1.012777241	0.286172253	3.539047661	0.000401573	0.002125064	3293	2798	2152	2118	2994	2305	3089	1657	1239	2736	1159	1990	sp	B4F6W9	TRIPC_XENTR	62.873	905	320	6	3469	6138	1153	2056	0	1182	B4F6W9	reviewed	TRIPC_XENTR	E3 ubiquitin-protein ligase TRIP12 (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase TRIP12) (Thyroid receptor-interacting protein 12) (TR-interacting protein 12) (TRIP-12)	trip12	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	2056	GO:0000209; GO:0005654; GO:0006281; GO:0006511; GO:0008270; GO:0033696; GO:0045995; GO:0061630; GO:0140861
g1423	399.2307952	1.23381328	0.269215835	4.582989259	4.58E-06	4.49E-05	1038	409	480	453	257	369	310	314	243	308	313	229	sp	Q15386	UBE3C_HUMAN	48.457	1102	529	16	1	3246	1	1083	0	953	Q15386	reviewed	UBE3C_HUMAN	Ubiquitin-protein ligase E3C (EC 2.3.2.26) (HECT-type ubiquitin transferase E3C) (Homologous to E6AP carboxyl terminus homologous protein 2) (HectH2) (RTA-associated ubiquitin ligase) (RAUL)	UBE3C KIAA0010 KIAA10	Homo sapiens (Human)	1083	GO:0000209; GO:0000502; GO:0006511; GO:0035519; GO:0061630; GO:0070936
g11349	399.7075767	1.791653027	0.350238343	5.115525084	3.13E-07	4.15E-06	567	1232	468	261	362	394	328	236	122	188	234	200	sp	Q9P2G1	AKIB1_HUMAN	48.886	763	342	9	1	2238	1	732	0	749	Q9P2G1	reviewed	AKIB1_HUMAN	Ankyrin repeat and IBR domain-containing protein 1 (EC 2.3.2.31)	ANKIB1 KIAA1386	Homo sapiens (Human)	1089	GO:0000151; GO:0000209; GO:0005737; GO:0006511; GO:0008270; GO:0031624; GO:0061630
g3038	61.01063256	-1.579435838	0.556635525	-2.837468625	0.004547282	0.01644582	34	46	18	32	0	37	155	94	65	140	119	105	sp	Q6J1I7	RN166_RAT	51.208	207	99	2	121	738	31	236	9.61E-66	207	Q6J1I7	reviewed	RN166_RAT	E3 ubiquitin-protein ligase RNF166 (EC 2.3.2.27) (RING finger protein 166) (RING-type E3 ubiquitin transferase RNF166)	Rnf166	Rattus norvegicus (Rat)	237	GO:0000209; GO:0005737; GO:0006511; GO:0006914; GO:0045087; GO:0046872; GO:0061630
g2851	687.8405896	1.31106572	0.280282031	4.677665984	2.90E-06	3.00E-05	973	682	557	1020	911	627	618	437	477	457	379	437	sp	Q9JLV2	TP4AP_MOUSE	42.51	781	393	14	112	2382	36	784	0	592	Q9JLV2	reviewed	TP4AP_MOUSE	Short transient receptor potential channel 4-associated protein (Trp4-associated protein) (Trpc4-associated protein) (Protein TAP1) (Rabex-5/Rin2-interacting protein) (TNF-receptor ubiquitous scaffolding/signaling protein) (Protein TRUSS)	Trpc4ap Trrp4ap	Mus musculus (Mouse)	797	GO:0006511; GO:0016567; GO:0019902; GO:0031464; GO:0048471; GO:0048820; GO:0080008; GO:0140627; GO:1990756
g15362	1318.780669	1.128709024	0.2653735	4.253284606	2.11E-05	0.000169055	2367	1293	1359	1304	1413	1341	1389	717	1011	885	1244	761	sp	O43242	PSMD3_HUMAN	65.868	501	163	2	22	1503	34	533	0	587	O43242	reviewed	PSMD3_HUMAN	26S proteasome non-ATPase regulatory subunit 3 (26S proteasome regulatory subunit RPN3) (26S proteasome regulatory subunit S3) (Proteasome subunit p58)	PSMD3	Homo sapiens (Human)	534	GO:0000502; GO:0005576; GO:0005634; GO:0005654; GO:0005829; GO:0006511; GO:0008541; GO:0016020; GO:0022624; GO:0030234; GO:0034774; GO:0042176; GO:0043161; GO:0070062; GO:1904813
g15763	1512.59845	2.135983467	0.332287437	6.428119838	1.29E-10	3.79E-09	1968	2431	1777	3466	1639	1106	912	624	772	952	404	438	sp	P53804	TTC3_HUMAN	34.715	193	118	3	184	759	1822	2007	2.01E-23	102	P53804	reviewed	TTC3_HUMAN	E3 ubiquitin-protein ligase TTC3 (EC 2.3.2.27) (Protein DCRR1) (RING finger protein 105) (RING-type E3 ubiquitin transferase TTC3) (TPR repeat protein D) (Tetratricopeptide repeat protein 3) (TPR repeat protein 3)	TTC3 DCRR1 RNF105 TPRD	Homo sapiens (Human)	2025	GO:0004842; GO:0005634; GO:0005654; GO:0005730; GO:0005794; GO:0005829; GO:0006511; GO:0046872; GO:0070936
g15764	7624.244303	1.913407162	0.223724102	8.552530304	1.20E-17	1.12E-15	10710	12188	9872	12283	8683	6790	5258	3339	3215	5187	3889	2611	sp	P53804	TTC3_HUMAN	29.796	245	167	4	1180	1905	490	732	1.26E-28	130	P53804	reviewed	TTC3_HUMAN	E3 ubiquitin-protein ligase TTC3 (EC 2.3.2.27) (Protein DCRR1) (RING finger protein 105) (RING-type E3 ubiquitin transferase TTC3) (TPR repeat protein D) (Tetratricopeptide repeat protein 3) (TPR repeat protein 3)	TTC3 DCRR1 RNF105 TPRD	Homo sapiens (Human)	2025	GO:0004842; GO:0005634; GO:0005654; GO:0005730; GO:0005794; GO:0005829; GO:0006511; GO:0046872; GO:0070936
g15765	615.4362869	2.168551354	0.394838403	5.492250339	3.97E-08	6.61E-07	617	868	699	1825	478	618	370	355	298	258	214	121	sp	O88196	TTC3_MOUSE	36.029	136	73	3	562	957	226	351	1.56E-12	74.3	O88196	reviewed	TTC3_MOUSE	E3 ubiquitin-protein ligase TTC3 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TTC3) (TPR repeat protein D) (Mtprd)	Ttc3 Kiaa4119	Mus musculus (Mouse)	1979	GO:0004842; GO:0005634; GO:0005773; GO:0005794; GO:0006511; GO:0030517; GO:0045665; GO:0046872; GO:0070936
g21739	3405.623432	1.74521288	0.378229832	4.614159788	3.95E-06	3.95E-05	5037	2304	3290	4889	5468	3889	2498	2095	2306	1490	1053	1597	sp	P25867	UBCD1_DROME	91.156	147	13	0	1	441	1	147	1.02E-88	258	P25867	reviewed	UBCD1_DROME	Ubiquitin-conjugating enzyme E2-17 kDa (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme D1) (Protein effete) (Ubiquitin carrier protein) (Ubiquitin-protein ligase)	eff UbcD1 CG7425	Drosophila melanogaster (Fruit fly)	147	GO:0000151; GO:0000209; GO:0000278; GO:0001745; GO:0001751; GO:0005524; GO:0005634; GO:0005829; GO:0006511; GO:0007140; GO:0016322; GO:0016567; GO:0030718; GO:0031145; GO:0031625; GO:0031647; GO:0045676; GO:0045879; GO:0048132; GO:0051276; GO:0061057; GO:0061631; GO:0097039
g11649	1218.598221	1.385387603	0.357560527	3.874554089	0.00010682	0.00068206	2198	1249	1323	1492	1523	922	2253	595	612	699	530	677	sp	Q9ES00	UBE4B_MOUSE	49.164	1076	493	9	337	3435	106	1170	0	1051	Q9ES00	reviewed	UBE4B_MOUSE	Ubiquitin conjugation factor E4 B (EC 2.3.2.27) (RING-type E3 ubiquitin transferase E4 B) (Ubiquitin fusion degradation protein 2)	Ube4b Ufd2 Ufd2a	Mus musculus (Mouse)	1173	GO:0000151; GO:0000209; GO:0003222; GO:0005524; GO:0005634; GO:0005737; GO:0006457; GO:0006511; GO:0006513; GO:0008626; GO:0009411; GO:0016567; GO:0019899; GO:0030163; GO:0031175; GO:0034450; GO:0034976; GO:0036503; GO:0043161; GO:0051082; GO:0051117; GO:0051865; GO:0061630
g11648	10502.00376	1.172249913	0.382405091	3.065466282	0.002173309	0.008902624	15901	20519	11256	4941	9416	12327	7133	4719	6691	7245	13877	6905	sp	Q9BXM7	PINK1_HUMAN	38.514	444	225	11	673	1998	179	576	3.96E-83	276	Q9BXM7	reviewed	PINK1_HUMAN	"Serine/threonine-protein kinase PINK1, mitochondrial (EC 2.7.11.1) (BRPK) (PTEN-induced putative kinase protein 1)"	PINK1	Homo sapiens (Human)	581	GO:0000287; GO:0000422; GO:0000423; GO:0000785; GO:0002020; GO:0002082; GO:0002931; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005739; GO:0005741; GO:0005743; GO:0005758; GO:0005783; GO:0005829; GO:0005856; GO:0006468; GO:0006511; GO:0006979; GO:0007005; GO:0010310; GO:0010629; GO:0010821; GO:0010857; GO:0010952; GO:0014046; GO:0016020; GO:0016239; GO:0016242; GO:0016301; GO:0016504; GO:0016567; GO:0018105; GO:0022904; GO:0030097; GO:0030424; GO:0030426; GO:0031396; GO:0031398; GO:0031625; GO:0032148; GO:0032226; GO:0033138; GO:0033603; GO:0034599; GO:0035307; GO:0035556; GO:0036289; GO:0038203; GO:0042981; GO:0043123; GO:0043254; GO:0043422; GO:0043524; GO:0044297; GO:0044877; GO:0045727; GO:0046329; GO:0048471; GO:0050821; GO:0051443; GO:0051881; GO:0051897; GO:0055131; GO:0061136; GO:0071456; GO:0072655; GO:0072656; GO:0090141; GO:0090200; GO:0090258; GO:0097237; GO:0097413; GO:0097449; GO:0098779; GO:0099074; GO:0106310; GO:1900407; GO:1901525; GO:1902803; GO:1902902; GO:1902958; GO:1903146; GO:1903214; GO:1903298; GO:1903377; GO:1903384; GO:1903751; GO:1903852; GO:1903955; GO:1904544; GO:1904841; GO:1904881; GO:2000377; GO:2000378; GO:2001171; GO:2001243
g12645	344.3604404	0.488016724	0.198779112	2.455070454	0.014085698	0.041190465	436	326	306	322	283	352	498	379	319	312	254	338	sp	Q9P0J7	KCMF1_HUMAN	60.641	343	116	5	1	1017	1	328	8.36E-130	380	Q9P0J7	reviewed	KCMF1_HUMAN	E3 ubiquitin-protein ligase KCMF1 (EC 2.3.2.27) (FGF-induced in gastric cancer) (Potassium channel modulatory factor) (PCMF) (ZZ-type zinc finger-containing protein 1)	KCMF1 FIGC ZZZ1	Homo sapiens (Human)	381	GO:0005576; GO:0005737; GO:0005764; GO:0005770; GO:0005829; GO:0005886; GO:0006511; GO:0006979; GO:0008270; GO:0043161; GO:0045202; GO:0061630; GO:0070534; GO:0070936; GO:0099536; GO:0141191; GO:1904813
g5945	184.5696942	1.605956014	0.627531425	2.55916429	0.010492414	0.032418123	164	694	243	32	28	403	192	101	78	125	57	118	sp	Q9N1T2	RPGR_CANLF	48.087	366	186	3	1	1089	1	365	3.47E-98	332	Q9N1T2	reviewed	RPGR_CANLF	X-linked retinitis pigmentosa GTPase regulator	RPGR	Canis lupus familiaris (Dog) (Canis familiaris)	1003	GO:0001750; GO:0005085; GO:0005737; GO:0005794; GO:0005813; GO:0006511; GO:0007601; GO:0016567; GO:0036064; GO:0036126; GO:0042073; GO:0060271; GO:0061630
g11157	123.7390592	-1.009199282	0.367267201	-2.747861172	0.00599854	0.02061043	85	105	108	82	20	45	257	156	97	362	197	166	sp	Q8BM54	MYLIP_MOUSE	29.36	344	224	7	1	1011	1	332	2.21E-39	148	Q8BM54	reviewed	MYLIP_MOUSE	E3 ubiquitin-protein ligase MYLIP (EC 2.3.2.27) (Inducible degrader of the LDL-receptor) (Idol) (Myosin regulatory light chain-interacting protein) (MIR) (RING-type E3 ubiquitin transferase MYLIP)	Mylip	Mus musculus (Mouse)	445	GO:0004842; GO:0005737; GO:0005856; GO:0005886; GO:0006511; GO:0007399; GO:0008092; GO:0010977; GO:0010989; GO:0016567; GO:0031648; GO:0032803; GO:0042632; GO:0045732; GO:0046872; GO:0061630; GO:0071404
g16729	199.7291642	1.253720501	0.328499184	3.816510249	0.000135352	0.000838282	431	210	141	227	230	172	199	135	146	101	131	145	sp	Q9VBP9	NPL4_DROME	51.266	316	143	1	1	915	337	652	4.29E-112	341	Q9VBP9	reviewed	NPL4_DROME	Nuclear protein localization protein 4 homolog	Npl4 CG4673	Drosophila melanogaster (Fruit fly)	652	GO:0005634; GO:0005654; GO:0005829; GO:0006511; GO:0031625; GO:0043130; GO:0043161; GO:0045879; GO:0046872; GO:0071795; GO:0098586
g16728	131.6924371	1.712846383	0.339533334	5.044707582	4.54E-07	5.77E-06	215	128	115	262	141	143	125	76	89	60	52	50	sp	P60670	NPL4_MOUSE	45.148	237	94	3	1	606	1	236	6.48E-67	196	P60670	reviewed	NPL4_MOUSE	Nuclear protein localization protein 4 homolog (Protein NPL4)	Nploc4 Kiaa1499 Npl4	Mus musculus (Mouse)	608	GO:0005634; GO:0005783; GO:0005829; GO:0006511; GO:0007030; GO:0030970; GO:0031625; GO:0032480; GO:0034098; GO:0036501; GO:0036503; GO:0039536; GO:0042175; GO:0043130; GO:0043161; GO:0044877; GO:0046872; GO:0051117
g3771	821.2952088	0.758690448	0.305762769	2.481304217	0.01309026	0.038752198	951	1341	1085	461	545	1011	1144	740	687	931	285	786	sp	Q7TPD1	FBX11_MOUSE	71.357	803	219	5	310	2709	136	930	0	1198	Q7TPD1	reviewed	FBX11_MOUSE	F-box only protein 11	Fbxo11	Mus musculus (Mouse)	930	GO:0004842; GO:0005654; GO:0005694; GO:0005730; GO:0005737; GO:0006511; GO:0007605; GO:0008270; GO:0010719; GO:0016274; GO:0016567; GO:0042981; GO:0043161; GO:0045732; GO:1904878; GO:1990756
g3351	823.2799639	0.876729929	0.179244119	4.891261887	1.00E-06	1.16E-05	1091	973	808	774	742	981	942	525	725	733	612	688	sp	Q9R049	AMFR_MOUSE	44.376	649	297	10	46	1986	16	602	2.28E-167	499	Q9R049	reviewed	AMFR_MOUSE	E3 ubiquitin-protein ligase AMFR (EC 2.3.2.36) (Autocrine motility factor receptor) (AMF receptor) (RING-type E3 ubiquitin transferase AMFR)	Amfr	Mus musculus (Mouse)	643	GO:0000151; GO:0000166; GO:0000209; GO:0004842; GO:0005783; GO:0005789; GO:0005794; GO:0005829; GO:0005886; GO:0006511; GO:0007611; GO:0016055; GO:0030425; GO:0030426; GO:0030674; GO:0030968; GO:0032991; GO:0034450; GO:0036503; GO:0036513; GO:0038023; GO:0038061; GO:0042802; GO:0043025; GO:0043130; GO:0044314; GO:0046872; GO:0048471; GO:0051087; GO:0051865; GO:0061630; GO:0070936; GO:0090090; GO:1904288; GO:1990381; GO:2000638
g1443	136.8993088	-1.386770276	0.403560719	-3.436336126	0.000589639	0.002945124	46	105	119	28	43	56	300	113	243	337	285	168	sp	F6UA42	UHRF1_XENTR	60.884	611	226	3	742	2565	175	775	0	722	F6UA42	reviewed	UHRF1_XENTR	E3 ubiquitin-protein ligase UHRF1 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase UHRF1) (Ubiquitin-like PHD and RING finger domain-containing protein 1) (Ubiquitin-like-containing PHD and RING finger domains protein 1)	uhrf1	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	775	GO:0000122; GO:0000785; GO:0000791; GO:0000792; GO:0004842; GO:0005634; GO:0005657; GO:0006511; GO:0008270; GO:0016567; GO:0031507; GO:0035064; GO:0042393; GO:0044027; GO:0044729
g22141	178.150983	-1.033678282	0.377023614	-2.741680478	0.006112577	0.020881715	163	142	166	144	22	33	369	345	262	275	262	219	sp	Q5RFS2	CSN3_PONAB	69.108	314	95	1	1	942	1	312	2.05E-157	452	Q5RFS2	reviewed	CSN3_PONAB	COP9 signalosome complex subunit 3 (SGN3) (Signalosome subunit 3)	COPS3 CSN3	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	423	GO:0000338; GO:0001701; GO:0005654; GO:0005829; GO:0006511; GO:0008180; GO:0048471; GO:1902162
g21569	1217.950281	4.19000539	0.497137734	8.42825861	3.51E-17	3.11E-15	1445	2102	3158	1032	2437	991	283	157	31	144	221	121	sp	Q6NW85	ARI1L_DANRE	31.313	198	111	7	520	1092	179	358	4.45E-21	100	Q6NW85	reviewed	ARI1L_DANRE	E3 ubiquitin-protein ligase arih1l (EC 2.3.2.31)	arih1l zgc:85905	Danio rerio (Zebrafish) (Brachydanio rerio)	533	GO:0000151; GO:0000209; GO:0004842; GO:0005634; GO:0005737; GO:0006511; GO:0008270; GO:0016567; GO:0031624; GO:0061630
g8682	228.0414242	1.014389559	0.336546425	3.014114801	0.002577303	0.01026047	351	292	293	246	243	114	172	220	248	145	118	181	sp	Q9CPX9	APC11_MOUSE	82.143	84	12	1	1	243	1	84	2.63E-41	132	Q9CPX9	reviewed	APC11_MOUSE	Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11)	Anapc11	Mus musculus (Mouse)	84	GO:0005634; GO:0005654; GO:0005680; GO:0005730; GO:0005737; GO:0006511; GO:0008270; GO:0016567; GO:0031145; GO:0034450; GO:0045842; GO:0051301; GO:0061630; GO:0070936; GO:0070979; GO:0097602; GO:0141198
g12673	1259.460511	2.470692471	0.316556332	7.804906183	5.95E-15	3.79E-13	1297	1731	1745	1625	1963	1889	695	407	489	513	209	466	sp	Q3ULA2	FBW1A_MOUSE	74.409	508	103	2	7	1449	98	605	0	787	Q3ULA2	reviewed	FBW1A_MOUSE	F-box/WD repeat-containing protein 1A (Beta-TrCP protein E3RS-IkappaB) (Beta-transducin repeat-containing protein) (Beta-TrCP) (E3RSIkappaB) (mE3RS-IkappaB) (F-box and WD repeats protein beta-TrCP) (HOS) (Ubiquitin ligase FWD1) (pIkappaB-E3 receptor subunit)	Btrc Fbw1 Fbxw1 Fwd1 Kiaa4123	Mus musculus (Mouse)	605	GO:0000209; GO:0004842; GO:0005634; GO:0005737; GO:0005829; GO:0006470; GO:0006508; GO:0006511; GO:0008013; GO:0016055; GO:0016567; GO:0019005; GO:0030163; GO:0031146; GO:0031648; GO:0033598; GO:0038061; GO:0042752; GO:0042753; GO:0043122; GO:0043161; GO:0045309; GO:0045862; GO:0045892; GO:0045893; GO:0046983; GO:0048511; GO:0051726; GO:0060444; GO:0060828; GO:0061136; GO:0061630; GO:0070936; GO:0071407; GO:1990756; GO:1990757
g11249	1489.931134	1.769784144	0.260869421	6.784176306	1.17E-11	4.12E-10	2167	1808	1514	2057	1977	1756	928	749	994	803	677	637	sp	Q9H0E2	TOLIP_HUMAN	47.855	303	119	6	1	888	1	271	7.64E-82	251	Q9H0E2	reviewed	TOLIP_HUMAN	Toll-interacting protein	TOLLIP	Homo sapiens (Human)	274	GO:0005150; GO:0005576; GO:0005737; GO:0005769; GO:0005829; GO:0006511; GO:0006914; GO:0006954; GO:0007165; GO:0016310; GO:0016604; GO:0019897; GO:0019900; GO:0030855; GO:0031624; GO:0031625; GO:0032183; GO:0032991; GO:0033235; GO:0035325; GO:0035578; GO:0035580; GO:0036010; GO:0043130; GO:0045087; GO:0045321; GO:0048471; GO:0060090; GO:0070062; GO:0070498
g10192	1250.012759	0.703821608	0.213519393	3.296288917	0.000979712	0.004536424	1875	1202	1395	1555	989	916	1474	1009	1289	1160	1128	857	sp	F6P3G4	PS11A_DANRE	72.115	416	116	0	7	1254	5	420	0	595	F6P3G4	reviewed	PS11A_DANRE	26S proteasome non-ATPase regulatory subunit 11A (26S proteasome regulatory subunit RPN6-A)	psmd11a	Danio rerio (Zebrafish) (Brachydanio rerio)	421	GO:0005198; GO:0005634; GO:0005829; GO:0006511; GO:0008541; GO:0022624; GO:0043248; GO:0048863
g17979	665.2467304	0.826266258	0.347744143	2.37607527	0.017497893	0.048946464	960	402	464	521	940	774	732	461	562	531	596	483	sp	Q8BW70	UBP38_MOUSE	53.205	312	146	0	37	972	233	544	1.66E-110	367	Q8BW70	reviewed	UBP38_MOUSE	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.4.19.12) (Deubiquitinating enzyme 38) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38)	Usp38	Mus musculus (Mouse)	1042	GO:0004843; GO:0005634; GO:0005829; GO:0006511; GO:0016579; GO:0032435; GO:0045824; GO:0140311
g19281	36.49433415	-2.235417589	0.825349348	-2.708450178	0.006759826	0.022688003	11	18	15	25	0	0	87	62	22	119	106	49	sp	Q5SPX3	RN215_MOUSE	33.208	265	159	7	214	966	112	372	3.82E-38	142	Q5SPX3	reviewed	RN215_MOUSE	RING finger protein 215	Rnf215	Mus musculus (Mouse)	379	GO:0005737; GO:0006511; GO:0016020; GO:0046872; GO:0061630
g19706	98.42564315	-1.067236329	0.359192235	-2.971212143	0.002966268	0.011514216	86	65	111	48	26	20	219	115	121	137	186	184	sp	Q810L3	CHFR_MOUSE	48.223	197	94	4	1249	1830	471	662	4.19E-54	199	Q810L3	reviewed	CHFR_MOUSE	E3 ubiquitin-protein ligase CHFR (EC 2.3.2.27) (Checkpoint with forkhead and RING finger domains protein) (RING-type E3 ubiquitin transferase CHFR)	Chfr	Mus musculus (Mouse)	664	GO:0000166; GO:0000209; GO:0000278; GO:0004842; GO:0005634; GO:0006511; GO:0016567; GO:0016605; GO:0031398; GO:0031648; GO:0032436; GO:0044779; GO:0044818; GO:0046872; GO:0051301; GO:0061630
g10576	623.9806381	0.952643775	0.281726841	3.38144485	0.000721057	0.003486307	1237	548	888	709	446	490	665	511	658	481	536	255	sp	Q5E964	PSD13_BOVIN	58.245	376	156	1	1	1128	1	375	9.27E-165	469	Q5E964	reviewed	PSD13_BOVIN	26S proteasome non-ATPase regulatory subunit 13 (26S proteasome regulatory subunit RPN9) (26S proteasome regulatory subunit S11) (26S proteasome regulatory subunit p40.5)	PSMD13	Bos taurus (Bovine)	376	GO:0005198; GO:0005634; GO:0005829; GO:0006511; GO:0008541; GO:0022624
g14231	1517.820971	1.885564604	0.390070871	4.833902617	1.34E-06	1.51E-05	2152	1228	1274	1382	2750	2379	777	617	956	549	832	591	sp	Q9UBF6	RBX2_HUMAN	91.86	86	7	0	103	360	28	113	8.51E-55	169	Q9UBF6	reviewed	RBX2_HUMAN	RING-box protein 2 (Rbx2) (EC 2.3.2.27) (EC 2.3.2.32) (CKII beta-binding protein 1) (CKBBP1) (RING finger protein 7) (Regulator of cullins 2) (Sensitive to apoptosis gene protein)	RNF7 RBX2 ROC2 SAG	Homo sapiens (Human)	113	GO:0005507; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006511; GO:0008270; GO:0016567; GO:0019788; GO:0030968; GO:0031466; GO:0038026; GO:0043161; GO:0043687; GO:0045116; GO:0051775; GO:0061630; GO:0061663; GO:0070979; GO:0097602; GO:2001222
g6268	35.01084523	-2.166671105	0.832827127	-2.601585653	0.009279389	0.029347895	14	0	16	27	0	13	62	76	69	72	101	25	sp	Q9WVS6	PRKN_MOUSE	49.415	427	188	11	118	1371	57	464	9.12E-135	399	Q9WVS6	reviewed	PRKN_MOUSE	E3 ubiquitin-protein ligase parkin (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase)	Prkn Park2	Mus musculus (Mouse)	464	GO:0000122; GO:0000139; GO:0000151; GO:0000209; GO:0000266; GO:0000422; GO:0000423; GO:0001664; GO:0001933; GO:0001963; GO:0001964; GO:0003714; GO:0003779; GO:0005634; GO:0005737; GO:0005739; GO:0005741; GO:0005783; GO:0005789; GO:0005794; GO:0005829; GO:0006511; GO:0006513; GO:0006979; GO:0007005; GO:0007612; GO:0007626; GO:0008013; GO:0008021; GO:0008270; GO:0008344; GO:0010506; GO:0010628; GO:0010629; GO:0010636; GO:0010637; GO:0010821; GO:0010918; GO:0010994; GO:0014069; GO:0015631; GO:0016235; GO:0016567; GO:0016607; GO:0019538; GO:0019900; GO:0019901; GO:0030163; GO:0030165; GO:0030424; GO:0030544; GO:0030672; GO:0031624; GO:0031625; GO:0031648; GO:0032232; GO:0032436; GO:0032991; GO:0034599; GO:0034976; GO:0035249; GO:0035774; GO:0042053; GO:0042415; GO:0042417; GO:0042802; GO:0042826; GO:0042981; GO:0043005; GO:0043025; GO:0043065; GO:0043123; GO:0043130; GO:0043161; GO:0043195; GO:0043274; GO:0043524; GO:0043653; GO:0044828; GO:0044877; GO:0045202; GO:0045944; GO:0046329; GO:0046676; GO:0046928; GO:0048471; GO:0050804; GO:0050821; GO:0051582; GO:0051583; GO:0051646; GO:0051865; GO:0051881; GO:0051967; GO:0061630; GO:0061734; GO:0070050; GO:0070534; GO:0070585; GO:0070842; GO:0070936; GO:0070979; GO:0085020; GO:0090090; GO:0090141; GO:0090201; GO:0090258; GO:0090394; GO:0097237; GO:0097602; GO:0097708; GO:0098691; GO:0098793; GO:0098794; GO:0098978; GO:0099072; GO:0099073; GO:0099074; GO:0140251; GO:1900242; GO:1900407; GO:1901526; GO:1902236; GO:1902254; GO:1902530; GO:1903265; GO:1903377; GO:1903382; GO:1903427; GO:1903542; GO:1903861; GO:1904049; GO:1904881; GO:1905232; GO:1905366; GO:1905477; GO:1990381; GO:1990444; GO:1990452; GO:2001171
g13023	124.1473063	0.647931683	0.236826842	2.735887869	0.006221222	0.021194146	121	123	159	197	67	118	177	110	112	109	105	98	sp	Q708Y0	EBF2_ARATH	28.745	247	153	8	301	1023	188	417	4.92E-10	65.9	Q708Y0	reviewed	EBF2_ARATH	EIN3-binding F-box protein 2	EBF2 At5g25350 F18G18.90	Arabidopsis thaliana (Mouse-ear cress)	623	GO:0005634; GO:0006511; GO:0009723; GO:0009873; GO:0010105; GO:0016567; GO:0019005
g6193	672.9773614	1.293571418	0.281986208	4.58735705	4.49E-06	4.42E-05	1049	939	559	641	868	643	684	409	402	560	494	311	sp	O08759	UBE3A_MOUSE	43.541	418	213	6	2155	3396	471	869	1.91E-92	319	O08759	reviewed	UBE3A_MOUSE	Ubiquitin-protein ligase E3A (EC 2.3.2.26) (HECT-type ubiquitin transferase E3A) (Oncogenic protein-associated protein E6-AP)	Ube3a	Mus musculus (Mouse)	870	GO:0000209; GO:0000502; GO:0001541; GO:0003713; GO:0004842; GO:0005634; GO:0005829; GO:0006511; GO:0008021; GO:0016567; GO:0030521; GO:0031398; GO:0032570; GO:0035037; GO:0035641; GO:0042220; GO:0042542; GO:0042752; GO:0043161; GO:0045944; GO:0046872; GO:0048167; GO:0048511; GO:0050804; GO:0050847; GO:0051865; GO:0051897; GO:0060736; GO:0061002; GO:0061630; GO:0061743; GO:0070936; GO:0098978; GO:0099524; GO:1904262; GO:1905528; GO:1990416; GO:2000058
g76	308.6779107	0.626081369	0.241211119	2.595574247	0.0094433	0.029800775	308	289	371	245	302	334	370	185	277	424	218	303	sp	E1B7X3	R146A_BOVIN	57.962	157	61	1	88	558	31	182	1.31E-57	196	E1B7X3	reviewed	R146A_BOVIN	E3 ubiquitin-protein ligase RNF146-A (EC 2.3.2.27) (RING finger protein 146-A) (RING-type E3 ubiquitin transferase RNF146-A)	RNF146A	Bos taurus (Bovine)	346	GO:0004842; GO:0005634; GO:0005737; GO:0005829; GO:0006511; GO:0008270; GO:0016055; GO:0051865; GO:0061630; GO:0070936; GO:0072572; GO:0090263
g11424	216.8127239	1.202779843	0.382797881	3.142075496	0.001677548	0.00715715	275	171	233	261	363	109	166	130	105	169	232	127	sp	Q9Y5A7	NUB1_HUMAN	34.307	548	321	9	34	1632	12	535	3.58E-78	263	Q9Y5A7	reviewed	NUB1_HUMAN	NEDD8 ultimate buster 1 (Negative regulator of ubiquitin-like proteins 1) (Renal carcinoma antigen NY-REN-18)	NUB1 NYREN18	Homo sapiens (Human)	615	GO:0005654; GO:0005730; GO:0005829; GO:0006511; GO:0016567; GO:0032436; GO:0034341; GO:0034612; GO:2000058
g20470	437.4401187	0.871798488	0.216707712	4.022923216	5.75E-05	0.000396097	517	563	464	440	464	365	568	346	329	394	354	286	sp	O95376	ARI2_HUMAN	57.639	432	180	2	130	1425	62	490	0	541	O95376	reviewed	ARI2_HUMAN	E3 ubiquitin-protein ligase ARIH2 (ARI-2) (Protein ariadne-2 homolog) (EC 2.3.2.31) (Triad1 protein)	ARIH2 ARI2 TRIAD1 HT005	Homo sapiens (Human)	493	GO:0000151; GO:0000209; GO:0004842; GO:0005634; GO:0005654; GO:0005737; GO:0006511; GO:0008270; GO:0016567; GO:0031624; GO:0043161; GO:0048588; GO:0061630; GO:0070534; GO:0070936; GO:0071425; GO:1903955
g11856	284.4299154	-1.929933428	0.313109785	-6.163759549	7.10E-10	1.77E-08	94	61	82	159	108	96	733	490	609	564	445	410	sp	Q923V4	FBX6_RAT	36.187	257	147	6	136	897	4	246	5.33E-49	167	Q923V4	reviewed	FBX6_RAT	F-box only protein 6 (F-box only protein 6b) (F-box protein that recognizes sugar chains 2) (F-box/G-domain protein 2)	Fbxo6 Fbg2 Fbs2 Fbxo6b	Rattus norvegicus (Rat)	284	GO:0005737; GO:0006281; GO:0006511; GO:0006516; GO:0006986; GO:0016567; GO:0019005; GO:0030246; GO:0031146; GO:0036503; GO:0044322; GO:0061630
g1093	124.6482565	6.591248015	1.238923969	5.320139232	1.04E-07	1.57E-06	139	101	705	18	61	320	0	21	0	0	0	3	sp	Q3T0J1	FBX4_BOVIN	30.986	213	128	5	373	957	46	257	5.44E-20	93.2	Q3T0J1	reviewed	FBX4_BOVIN	F-box only protein 4	FBXO4	Bos taurus (Bovine)	387	GO:0000209; GO:0000723; GO:0005737; GO:0006511; GO:0019005; GO:0031146; GO:0031398
g19466	367.9968301	1.145096409	0.38635888	2.963815424	0.003038505	0.011733931	771	232	367	435	358	388	605	382	167	290	117	229	sp	Q92890	UFD1_HUMAN	62.662	308	107	4	4	909	1	306	5.32E-130	375	Q92890	reviewed	UFD1_HUMAN	Ubiquitin recognition factor in ER-associated degradation protein 1 (Ubiquitin fusion degradation protein 1) (UB fusion protein 1)	UFD1 UFD1L	Homo sapiens (Human)	307	GO:0001501; GO:0004843; GO:0005634; GO:0005654; GO:0005829; GO:0006511; GO:0030970; GO:0031593; GO:0032480; GO:0034098; GO:0036435; GO:0036501; GO:0036503; GO:0039536; GO:0043161; GO:0071218
g6469	1759.132367	1.790909548	0.345796814	5.179080527	2.23E-07	3.09E-06	3034	1867	1879	1339	2688	2375	1655	778	505	1257	545	1159	sp	O95628	CNOT4_HUMAN	85.106	235	35	0	46	750	10	244	2.60E-143	437	O95628	reviewed	CNOT4_HUMAN	CCR4-NOT transcription complex subunit 4 (EC 2.3.2.27) (CCR4-associated factor 4) (E3 ubiquitin-protein ligase CNOT4) (Potential transcriptional repressor NOT4Hp) (RING-type E3 ubiquitin transferase CNOT4)	CNOT4 NOT4	Homo sapiens (Human)	575	GO:0000289; GO:0003723; GO:0004842; GO:0005634; GO:0005829; GO:0006511; GO:0016567; GO:0030014; GO:0045652; GO:0046872; GO:0051865
g21198	4325.274026	1.641036564	0.201053988	8.162168676	3.29E-16	2.51E-14	7978	6432	4564	5312	4418	4661	3487	2130	2894	2304	2156	2370	sp	Q29504	UBA1_RABIT	62.417	1059	359	5	31	3096	2	1058	0	1390	Q29504	reviewed	UBA1_RABIT	Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Ubiquitin-activating enzyme E1)	UBA1 UBE1	Oryctolagus cuniculus (Rabbit)	1058	GO:0004839; GO:0005524; GO:0005634; GO:0005737; GO:0005739; GO:0006511; GO:0006974
g19751	119.4657795	0.799519106	0.220382274	3.627873929	0.000285765	0.001591762	163	115	195	91	83	140	144	83	89	120	95	111	sp	Q91YT2	RN185_MOUSE	68.235	170	45	2	217	717	29	192	3.35E-48	160	Q91YT2	reviewed	RN185_MOUSE	E3 ubiquitin-protein ligase RNF185 (EC 2.3.2.27) (RING finger protein 185)	Rnf185	Mus musculus (Mouse)	192	GO:0005741; GO:0005783; GO:0005789; GO:0006511; GO:0006914; GO:0036503; GO:0043130; GO:0044314; GO:0044390; GO:0044877; GO:0045087; GO:0046872; GO:0051607; GO:0051865; GO:0060340; GO:0061630; GO:1904294
g20332	2258.257008	0.892796394	0.269143477	3.317176412	0.000909322	0.004246946	3290	3166	2414	1352	2377	2116	2721	1632	1262	2464	2059	1601	sp	Q7Z6Z7	HUWE1_HUMAN	63.043	1334	430	15	1	3963	1	1284	0	1603	Q7Z6Z7	reviewed	HUWE1_HUMAN	"E3 ubiquitin-protein ligase HUWE1 (EC 2.3.2.26) (ARF-binding protein 1) (ARF-BP1) (HECT, UBA and WWE domain-containing protein 1) (HECT-type E3 ubiquitin transferase HUWE1) (Homologous to E6AP carboxyl terminus homologous protein 9) (HectH9) (Large structure of UREB1) (LASU1) (Mcl-1 ubiquitin ligase E3) (Mule) (Upstream regulatory element-binding protein 1) (URE-B1) (URE-binding protein 1)"	HUWE1 KIAA0312 KIAA1578 UREB1 HSPC272	Homo sapiens (Human)	4374	GO:0000139; GO:0000209; GO:0003677; GO:0003723; GO:0004842; GO:0005576; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005829; GO:0006284; GO:0006511; GO:0006513; GO:0007030; GO:0010637; GO:0016020; GO:0030154; GO:0031398; GO:0032922; GO:0034774; GO:0061025; GO:0061630; GO:0070062; GO:0098779; GO:0140852; GO:1903955; GO:1904813
g14809	358.2547401	-1.489900755	0.37466568	-3.976613909	6.99E-05	0.000470989	150	128	238	162	37	285	705	652	699	600	671	473	sp	Q5RKH6	OS9_RAT	53.689	244	108	3	82	798	31	274	6.82E-84	281	Q5RKH6	reviewed	OS9_RAT	Protein OS-9	Os9	Rattus norvegicus (Rat)	666	GO:0002020; GO:0005788; GO:0006511; GO:0006605; GO:0006621; GO:0016567; GO:0030246; GO:0030968; GO:0030970; GO:0034976; GO:0036503; GO:1904153
g22410	594.6476438	1.269024087	0.33027333	3.842345029	0.000121864	0.000767159	935	732	693	258	532	1115	561	385	360	460	305	484	sp	Q9NV58	RN19A_HUMAN	56.314	586	220	9	25	1692	42	621	2.85E-176	530	Q9NV58	reviewed	RN19A_HUMAN	E3 ubiquitin-protein ligase RNF19A (EC 2.3.2.31) (Double ring-finger protein) (Dorfin) (RING finger protein 19A) (p38)	RNF19A RNF19	Homo sapiens (Human)	838	GO:0000151; GO:0000209; GO:0000226; GO:0005737; GO:0005813; GO:0005829; GO:0006511; GO:0008270; GO:0016020; GO:0031624; GO:0061630; GO:0098686; GO:0098794; GO:0098978; GO:0099576
g2814	2947.511951	1.131683218	0.425300621	2.660901867	0.007793167	0.025473517	2455	1555	2387	8431	3262	2015	2256	1696	2302	1376	2276	1950	sp	Q6TEM9	MYLIA_DANRE	40.315	444	244	9	1	1299	1	434	5.67E-90	284	Q6TEM9	reviewed	MYLIA_DANRE	E3 ubiquitin-protein ligase MYLIP-A (EC 2.3.2.27) (Myosin regulatory light chain-interacting protein A) (MIR-A) (RING-type E3 ubiquitin transferase MYLIP-A)	mylipa mir mylip si:ch211-266j17.1	Danio rerio (Zebrafish) (Brachydanio rerio)	472	GO:0004842; GO:0005737; GO:0005829; GO:0005856; GO:0006511; GO:0007369; GO:0016567; GO:0030178; GO:0046872
g18086	339.7330394	-1.014586149	0.229064791	-4.429254031	9.46E-06	8.47E-05	256	298	314	162	86	113	686	665	765	374	486	312	sp	P15374	UCHL3_HUMAN	50.442	226	112	0	16	693	5	230	8.11E-73	224	P15374	reviewed	UCHL3_HUMAN	Ubiquitin carboxyl-terminal hydrolase isozyme L3 (UCH-L3) (EC 3.4.19.12) (Ubiquitin thioesterase L3)	UCHL3	Homo sapiens (Human)	230	GO:0004843; GO:0005654; GO:0005737; GO:0005829; GO:0006511; GO:0008233; GO:0016567; GO:0016579; GO:0019784; GO:0030163; GO:0043130; GO:0043687
g15594	2139.17528	1.34141007	0.2941558	4.560202681	5.11E-06	4.94E-05	2928	1893	2049	2674	2898	2402	2607	1431	1206	1346	919	1373	sp	P22682	CBL_MOUSE	67.089	395	120	2	76	1260	49	433	0	588	P22682	reviewed	CBL_MOUSE	E3 ubiquitin-protein ligase CBL (EC 2.3.2.27) (Casitas B-lineage lymphoma proto-oncogene) (Proto-oncogene c-Cbl) (RING-type E3 ubiquitin transferase CBL) (Signal transduction protein CBL)	Cbl	Mus musculus (Mouse)	913	GO:0000209; GO:0001784; GO:0005509; GO:0005794; GO:0005829; GO:0005886; GO:0005925; GO:0005929; GO:0006468; GO:0006511; GO:0006513; GO:0006974; GO:0007165; GO:0007166; GO:0008584; GO:0010332; GO:0014823; GO:0016567; GO:0016600; GO:0017124; GO:0019901; GO:0030424; GO:0030426; GO:0030971; GO:0032487; GO:0033574; GO:0036120; GO:0036312; GO:0042059; GO:0042594; GO:0043066; GO:0043303; GO:0045121; GO:0045453; GO:0045471; GO:0046875; GO:0048260; GO:0048471; GO:0051865; GO:0051897; GO:0061630; GO:0070086; GO:0071456; GO:1990090; GO:1990782; GO:2000583
g22170	39.69443849	-1.419941742	0.361041446	-3.932905095	8.39E-05	0.000553213	29	39	29	12	6	10	150	75	71	83	40	24	sp	P25867	UBCD1_DROME	76.027	146	35	0	1	438	1	146	1.69E-70	211	P25867	reviewed	UBCD1_DROME	Ubiquitin-conjugating enzyme E2-17 kDa (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme D1) (Protein effete) (Ubiquitin carrier protein) (Ubiquitin-protein ligase)	eff UbcD1 CG7425	Drosophila melanogaster (Fruit fly)	147	GO:0000151; GO:0000209; GO:0000278; GO:0001745; GO:0001751; GO:0005524; GO:0005634; GO:0005829; GO:0006511; GO:0007140; GO:0016322; GO:0016567; GO:0030718; GO:0031145; GO:0031625; GO:0031647; GO:0045676; GO:0045879; GO:0048132; GO:0051276; GO:0061057; GO:0061631; GO:0097039
g9023	190.5896121	-0.600425487	0.23804138	-2.522357618	0.011657113	0.035327438	172	133	107	106	120	122	454	274	203	267	289	214	sp	Q8C7R4	UBA6_MOUSE	58.537	205	85	0	1	615	844	1048	1.65E-71	237	Q8C7R4	reviewed	UBA6_MOUSE	Ubiquitin-like modifier-activating enzyme 6 (Ubiquitin-activating enzyme 6) (EC 6.2.1.45) (Ubiquitin-activating enzyme E1-like protein 2) (E1-L2)	Uba6 Ube1l2	Mus musculus (Mouse)	1053	GO:0004792; GO:0004839; GO:0005524; GO:0005737; GO:0006511; GO:0007612; GO:0007626; GO:0016567; GO:0016779; GO:0019780; GO:0021764; GO:0021766; GO:0060996
g9022	688.2371499	-0.566740492	0.194053282	-2.920540621	0.003494246	0.013169726	681	457	420	498	282	535	1706	1029	774	980	923	734	sp	A0AVT1	UBA6_HUMAN	54.388	752	335	6	16	2259	38	785	0	855	A0AVT1	reviewed	UBA6_HUMAN	Ubiquitin-like modifier-activating enzyme 6 (Ubiquitin-activating enzyme 6) (EC 6.2.1.45) (Monocyte protein 4) (MOP-4) (Ubiquitin-activating enzyme E1-like protein 2) (E1-L2)	UBA6 MOP4 UBE1L2	Homo sapiens (Human)	1052	GO:0004792; GO:0004839; GO:0005524; GO:0005737; GO:0005829; GO:0006511; GO:0007612; GO:0007626; GO:0016567; GO:0016779; GO:0019780; GO:0021764; GO:0021766; GO:0060996
g23479	309.6371803	1.771811079	0.350165072	5.059930935	4.19E-07	5.39E-06	463	205	275	406	496	434	194	138	198	177	124	130	sp	P46379	BAG6_HUMAN	43.094	181	92	4	4	534	17	190	8.74E-27	112	P46379	reviewed	BAG6_HUMAN	Large proline-rich protein BAG6 (BAG family molecular chaperone regulator 6) (BCL2-associated athanogene 6) (BAG-6) (HLA-B-associated transcript 3) (Protein G3) (Protein Scythe)	BAG6 BAT3 G3	Homo sapiens (Human)	1132	GO:0001822; GO:0002429; GO:0005102; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006325; GO:0006511; GO:0006620; GO:0006915; GO:0007130; GO:0007283; GO:0007420; GO:0010498; GO:0016020; GO:0018393; GO:0030101; GO:0030154; GO:0030324; GO:0030544; GO:0031593; GO:0031625; GO:0031647; GO:0032435; GO:0036503; GO:0036506; GO:0042771; GO:0042802; GO:0043022; GO:0043066; GO:0043161; GO:0043231; GO:0045861; GO:0045995; GO:0050821; GO:0051787; GO:0060090; GO:0061857; GO:0070059; GO:0070062; GO:0070628; GO:0071816; GO:0071818; GO:0140677; GO:1904294; GO:1990381
g23478	1715.613008	1.722633636	0.35175792	4.897213505	9.72E-07	1.13E-05	2700	1074	1432	2661	2802	1851	1439	839	898	910	755	744	sp	P46379	BAG6_HUMAN	28.741	421	238	8	1366	2592	756	1126	1.12E-39	162	P46379	reviewed	BAG6_HUMAN	Large proline-rich protein BAG6 (BAG family molecular chaperone regulator 6) (BCL2-associated athanogene 6) (BAG-6) (HLA-B-associated transcript 3) (Protein G3) (Protein Scythe)	BAG6 BAT3 G3	Homo sapiens (Human)	1132	GO:0001822; GO:0002429; GO:0005102; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006325; GO:0006511; GO:0006620; GO:0006915; GO:0007130; GO:0007283; GO:0007420; GO:0010498; GO:0016020; GO:0018393; GO:0030101; GO:0030154; GO:0030324; GO:0030544; GO:0031593; GO:0031625; GO:0031647; GO:0032435; GO:0036503; GO:0036506; GO:0042771; GO:0042802; GO:0043022; GO:0043066; GO:0043161; GO:0043231; GO:0045861; GO:0045995; GO:0050821; GO:0051787; GO:0060090; GO:0061857; GO:0070059; GO:0070062; GO:0070628; GO:0071816; GO:0071818; GO:0140677; GO:1904294; GO:1990381
g2493	873.9948659	1.034430788	0.223084129	4.636953739	3.54E-06	3.58E-05	1828	786	1170	1031	599	748	1166	779	785	633	464	507	sp	Q9PTW9	PSA7_CARAU	86.758	219	29	0	4	660	3	221	7.87E-135	383	Q9PTW9	reviewed	PSA7_CARAU	Proteasome subunit alpha type-7 (Proteasome subunit alpha 4)	psma7	Carassius auratus (Goldfish)	251	GO:0005634; GO:0005737; GO:0005839; GO:0006511; GO:0010498; GO:0019773
g20134	218.8541245	-0.749021424	0.215000001	-3.483820558	0.000494311	0.002534242	142	184	129	201	75	117	436	315	287	444	253	287	sp	Q5F3N6	BAP1_CHICK	42.838	740	343	11	1	2154	1	682	1.08E-161	487	Q5F3N6	reviewed	BAP1_CHICK	Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1-associated protein 1)	BAP1 RCJMB04_11f19	Gallus gallus (Chicken)	700	GO:0001558; GO:0003682; GO:0004843; GO:0005634; GO:0005737; GO:0006325; GO:0006511; GO:0016579; GO:0035517; GO:0045892; GO:0051726; GO:0071108
g9303	2581.872791	1.142848562	0.219373955	5.209590913	1.89E-07	2.67E-06	4054	2700	2690	3377	2527	2534	2663	1976	2131	1928	1271	1805	sp	Q9UMX0	UBQL1_HUMAN	58.609	302	111	2	481	1344	179	480	6.68E-102	323	Q9UMX0	reviewed	UBQL1_HUMAN	Ubiquilin-1 (Protein linking IAP with cytoskeleton 1) (PLIC-1) (hPLIC-1)	UBQLN1 DA41 PLIC1	Homo sapiens (Human)	589	GO:0000045; GO:0000502; GO:0005654; GO:0005737; GO:0005776; GO:0005783; GO:0005829; GO:0005886; GO:0006511; GO:0016235; GO:0016236; GO:0016241; GO:0019900; GO:0031396; GO:0031398; GO:0031410; GO:0031593; GO:0032991; GO:0034140; GO:0034976; GO:0035973; GO:0036503; GO:0042802; GO:0048471; GO:0071456; GO:0097352; GO:1901340; GO:1902175; GO:1904294
g6282	495.6749398	0.708503121	0.172614957	4.104529149	4.05E-05	0.000295834	593	722	428	571	379	449	621	447	392	461	427	406	sp	Q9Z2A5	ATE1_MOUSE	53.036	247	113	1	103	834	269	515	5.63E-89	276	Q9Z2A5	reviewed	ATE1_MOUSE	Arginyl-tRNA--protein transferase 1 (Arginyltransferase 1) (R-transferase 1) (EC 2.3.2.8) (Arginine-tRNA--protein transferase 1)	Ate1	Mus musculus (Mouse)	516	GO:0004057; GO:0005634; GO:0005737; GO:0006511; GO:0010498
g6283	641.2477463	0.816613825	0.191304049	4.268669847	1.97E-05	0.000159363	789	1032	667	726	458	556	833	582	605	640	354	445	sp	O95260	ATE1_HUMAN	58.163	98	41	0	10	303	10	107	3.77E-36	137	O95260	reviewed	ATE1_HUMAN	Arginyl-tRNA--protein transferase 1 (Arginyltransferase 1) (R-transferase 1) (EC 2.3.2.8) (Arginine-tRNA--protein transferase 1)	ATE1	Homo sapiens (Human)	518	GO:0004057; GO:0005634; GO:0005737; GO:0006511; GO:0006979; GO:0010498; GO:0016598
g22627	88.05611698	-1.18851251	0.420839539	-2.824146499	0.004740671	0.017030898	40	57	79	54	21	28	149	150	63	121	279	115	sp	Q5XIU5	PSMF1_RAT	33.333	75	50	0	100	324	65	139	2.39E-17	62.4	Q5XIU5	reviewed	PSMF1_RAT	Proteasome inhibitor PI31 subunit	Psmf1	Rattus norvegicus (Rat)	271	GO:0000502; GO:0004866; GO:0005783; GO:0005829; GO:0006511; GO:0042803; GO:0043161; GO:0046982; GO:0048471; GO:0070628; GO:1901799
g9683	417.6186251	-2.093988274	0.33573582	-6.237011814	4.46E-10	1.16E-08	127	232	221	164	60	59	1165	879	438	992	868	656	sp	Q6ZT12	UBR3_HUMAN	33.293	817	434	17	1789	3951	1082	1883	8.02E-122	421	Q6ZT12	reviewed	UBR3_HUMAN	E3 ubiquitin-protein ligase UBR3 (EC 2.3.2.27) (N-recognin-3) (RING-type E3 ubiquitin transferase UBR3) (Ubiquitin-protein ligase E3-alpha-3) (Ubiquitin-protein ligase E3-alpha-III) (Zinc finger protein 650)	UBR3 KIAA2024 ZNF650	Homo sapiens (Human)	1888	GO:0000151; GO:0001701; GO:0001967; GO:0004842; GO:0005737; GO:0006511; GO:0007608; GO:0008270; GO:0009792; GO:0016020; GO:0016567; GO:0042048; GO:0045732; GO:0061630; GO:0071596; GO:1904878
g16612	121.5612444	-1.67837445	0.396996386	-4.227681942	2.36E-05	0.000187219	35	95	81	41	30	22	199	223	124	229	267	281	sp	Q5ZHY5	CHIP_CHICK	59.286	280	112	1	4	837	35	314	2.25E-117	342	Q5ZHY5	reviewed	CHIP_CHICK	E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (RING-type E3 ubiquitin transferase CHIP) (STIP1 homology and U box-containing protein 1)	STUB1 RCJMB04_32b21	Gallus gallus (Chicken)	314	GO:0000209; GO:0004842; GO:0005634; GO:0005737; GO:0005739; GO:0006281; GO:0006511; GO:0006515; GO:0030018; GO:0034450; GO:0042803; GO:0043161; GO:0045862; GO:0051087; GO:0061630; GO:0071218
g12805	435.2743774	1.555237448	0.382360689	4.067461673	4.75E-05	0.000338461	528	841	558	263	576	448	549	177	131	398	267	183	sp	Q8TDB6	DTX3L_HUMAN	64.211	95	34	0	799	1083	646	740	9.39E-26	112	Q8TDB6	reviewed	DTX3L_HUMAN	E3 ubiquitin-protein ligase DTX3L (EC 2.3.2.27) (B-lymphoma- and BAL-associated protein) (Protein deltex-3-like) (RING-type E3 ubiquitin transferase DTX3L) (Rhysin-2) (Rhysin2)	DTX3L BBAP	Homo sapiens (Human)	740	GO:0000077; GO:0002230; GO:0004842; GO:0004857; GO:0005634; GO:0005654; GO:0005737; GO:0005764; GO:0005765; GO:0005829; GO:0006302; GO:0006511; GO:0007219; GO:0008333; GO:0015031; GO:0019899; GO:0031901; GO:0032092; GO:0032991; GO:0035563; GO:0042393; GO:0044389; GO:0045087; GO:0045893; GO:0046872; GO:0051444; GO:0051607; GO:0051865; GO:0070936; GO:0097677; GO:0140768; GO:0140852; GO:0140861; GO:0141000; GO:1900182; GO:1902966; GO:2000646
g7741	603.167444	-0.667908885	0.159541932	-4.186415918	2.83E-05	0.000219567	448	492	502	425	264	284	1314	899	890	975	766	634	sp	Q3U1J4	DDB1_MOUSE	74.781	1142	285	3	1	3423	1	1140	0	1806	Q3U1J4	reviewed	DDB1_MOUSE	DNA damage-binding protein 1 (DDB p127 subunit) (Damage-specific DNA-binding protein 1) (UV-damaged DNA-binding factor)	Ddb1	Mus musculus (Mouse)	1140	GO:0003684; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0006281; GO:0006511; GO:0006915; GO:0006974; GO:0007056; GO:0010498; GO:0016055; GO:0016567; GO:0019076; GO:0031464; GO:0031465; GO:0034644; GO:0035234; GO:0035861; GO:0042752; GO:0043066; GO:0043161; GO:0044725; GO:0044877; GO:0045070; GO:0045722; GO:0045732; GO:0046726; GO:0048511; GO:0051093; GO:0051702; GO:0070914; GO:0071987; GO:0080008; GO:0097602; GO:0160072; GO:1901990; GO:2000242
g19157	1461.49255	1.305860853	0.314227254	4.155784823	3.24E-05	0.000245989	1795	2274	1202	839	1893	2061	1222	786	634	1367	1208	954	sp	Q8CJB9	BRE1B_RAT	65.13	347	121	0	1888	2928	656	1002	1.20E-139	446	Q8CJB9	reviewed	BRE1B_RAT	E3 ubiquitin-protein ligase BRE1B (BRE1-B) (EC 2.3.2.27) (RING finger protein 40) (RING-type E3 ubiquitin transferase BRE1B) (Syntaxin-1-interacting RING finger protein) (Protein staring)	Rnf40 Bre1b	Rattus norvegicus (Rat)	1002	GO:0000151; GO:0003730; GO:0004842; GO:0005634; GO:0006325; GO:0006511; GO:0016567; GO:0017075; GO:0031624; GO:0031625; GO:0032991; GO:0033503; GO:0042803; GO:0043434; GO:0045944; GO:0046872; GO:0061630; GO:1901800; GO:1902916
g4903	302.5518872	-0.858589698	0.213041663	-4.030149246	5.57E-05	0.000385964	307	246	224	164	62	178	618	484	421	569	423	345	sp	Q6NRG0	RNF8B_XENLA	42.135	178	91	4	1279	1812	292	457	3.69E-34	140	Q6NRG0	reviewed	RNF8B_XENLA	E3 ubiquitin-protein ligase rnf8-B (EC 2.3.2.27) (RING finger protein 8-B) (RING-type E3 ubiquitin transferase rnf8-B)	rnf8-B	Xenopus laevis (African clawed frog)	532	GO:0000151; GO:0000781; GO:0003682; GO:0005634; GO:0006302; GO:0006303; GO:0006511; GO:0006974; GO:0008270; GO:0010212; GO:0034244; GO:0035092; GO:0035861; GO:0040029; GO:0042393; GO:0042803; GO:0043130; GO:0045190; GO:0045739; GO:0061630; GO:0070534; GO:0070936; GO:0085020; GO:0140861; GO:1905168
g18018	808.1465234	0.880856899	0.20664149	4.262730097	2.02E-05	0.000163124	1089	1063	751	815	712	868	892	575	639	587	852	567	sp	Q5U2S1	NFIP1_RAT	31.98	197	127	2	34	624	23	212	1.70E-24	99.4	Q5U2S1	reviewed	NFIP1_RAT	NEDD4 family-interacting protein 1	Ndfip1 N4wbp5	Rattus norvegicus (Rat)	221	GO:0000139; GO:0002761; GO:0002829; GO:0005576; GO:0005783; GO:0005794; GO:0005938; GO:0006511; GO:0006879; GO:0007034; GO:0010008; GO:0010629; GO:0030001; GO:0030163; GO:0030425; GO:0031398; GO:0032713; GO:0035739; GO:0045202; GO:0045619; GO:0045732; GO:0048294; GO:0048302; GO:0048471; GO:0050699; GO:0050728; GO:0051224; GO:2000562
g1007	174.9504684	0.680930117	0.280348948	2.428866322	0.015146116	0.043618994	249	123	213	175	164	158	275	167	105	174	98	185	sp	Q80Z37	TOPRS_MOUSE	37.38	313	138	7	91	906	104	399	3.64E-53	203	Q80Z37	reviewed	TOPRS_MOUSE	E3 ubiquitin-protein ligase Topors (EC 2.3.2.27) (RING-type E3 ubiquitin transferase Topors) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3)	Topors	Mus musculus (Mouse)	1033	GO:0000151; GO:0000209; GO:0000922; GO:0000930; GO:0003677; GO:0003823; GO:0004842; GO:0005634; GO:0005814; GO:0006511; GO:0006513; GO:0006974; GO:0008630; GO:0016605; GO:0016607; GO:0016925; GO:0019789; GO:0032391; GO:0034504; GO:0036064; GO:0042127; GO:0042771; GO:0043161; GO:0044547; GO:0045893; GO:0046872; GO:0051457; GO:0061630; GO:0070936
g4138	211.3295892	-0.956085103	0.345996512	-2.763279602	0.005722372	0.019839243	180	133	181	146	43	92	461	249	235	290	576	217	sp	Q5R4I2	RNF8_PONAB	42.708	96	55	0	211	498	387	482	5.38E-20	92.8	Q5R4I2	reviewed	RNF8_PONAB	E3 ubiquitin-protein ligase RNF8 (EC 2.3.2.27) (RING finger protein 8) (RING-type E3 ubiquitin transferase RNF8)	RNF8	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	486	GO:0000151; GO:0000781; GO:0003682; GO:0005634; GO:0005737; GO:0005829; GO:0006302; GO:0006303; GO:0006511; GO:0006974; GO:0008270; GO:0010212; GO:0030496; GO:0034244; GO:0035092; GO:0035861; GO:0040029; GO:0042393; GO:0042803; GO:0043130; GO:0045190; GO:0045739; GO:0051301; GO:0061630; GO:0070534; GO:0070936; GO:0085020; GO:0140861; GO:1905168
g1373	123.460927	-0.972298117	0.350381131	-2.774972824	0.005520632	0.019279213	44	89	145	65	42	53	233	249	160	276	174	107	sp	Q96EH8	NEUL3_HUMAN	30.464	151	95	5	10	450	19	163	3.53E-10	65.5	Q96EH8	reviewed	NEUL3_HUMAN	E3 ubiquitin-protein ligase NEURL3 (EC 2.3.2.27) (Lung-inducible neuralized-related C3CH4 RING domain protein) (Neuralized-like protein 3) (RING-type E3 ubiquitin transferase NEURL3)	NEURL3 LINCR	Homo sapiens (Human)	262	GO:0005769; GO:0016567; GO:0045087; GO:0046872; GO:0061630; GO:0070086
g184	164.1851131	-1.143359839	0.315785983	-3.620679509	0.00029383	0.00162776	80	136	92	145	38	49	375	236	291	219	284	243	sp	Q8K0G5	EIPR1_MOUSE	65.206	388	133	1	1	1164	1	386	7.33E-175	495	Q8K0G5	reviewed	EIPR1_MOUSE	EARP and GARP complex-interacting protein 1 (Endosome-associated recycling protein-interacting protein) (Golgi-associated retrograde protein-interacting protein) (Tumor-suppressing STF cDNA 1 protein) (Tumor-suppressing subchromosomal transferable fragment candidate gene 1 protein)	Eipr1 Tssc1	Mus musculus (Mouse)	386	GO:0000938; GO:0005802; GO:0016567; GO:0032456; GO:0050796; GO:1904811; GO:1905281; GO:1990745; GO:2001137
g258	215.208974	-1.500983642	0.487397395	-3.079588969	0.002072864	0.008558189	78	307	110	18	44	91	569	266	348	500	331	308	sp	O35709	ENC1_MOUSE	36.975	119	72	1	379	735	27	142	7.89E-16	82	O35709	reviewed	ENC1_MOUSE	Ectoderm-neural cortex protein 1 (ENC-1)	Enc1 Enc-1	Mus musculus (Mouse)	589	GO:0000785; GO:0003779; GO:0005654; GO:0005737; GO:0005856; GO:0010499; GO:0010976; GO:0016363; GO:0016567; GO:0017148; GO:0031463; GO:0043025
g9940	182.8343521	-0.613666039	0.252000952	-2.435173493	0.014884651	0.043052756	176	188	135	91	47	142	443	197	344	273	169	226	sp	Q9D4H8	CUL2_MOUSE	59.383	746	298	4	1	2226	1	745	0	939	Q9D4H8	reviewed	CUL2_MOUSE	Cullin-2 (CUL-2)	Cul2	Mus musculus (Mouse)	745	GO:0005654; GO:0005730; GO:0016567; GO:0019005; GO:0030163; GO:0030674; GO:0030891; GO:0031146; GO:0031462; GO:0031625; GO:0044877; GO:0140627; GO:0160072
g14623	453.7549971	-1.472826016	0.344254722	-4.278303013	1.88E-05	0.000153486	143	226	381	266	133	96	1043	737	696	1183	459	820	sp	O15541	R113A_HUMAN	55.758	330	133	7	16	978	13	338	1.07E-119	351	O15541	reviewed	R113A_HUMAN	E3 ubiquitin-protein ligase RNF113A (EC 2.3.2.27) (Cwc24 homolog) (RING finger protein 113A) (Zinc finger protein 183)	RNF113A RNF113 ZNF183	Homo sapiens (Human)	343	GO:0000398; GO:0005634; GO:0005654; GO:0005684; GO:0006281; GO:0016567; GO:0016607; GO:0034247; GO:0046872; GO:0061630; GO:0070100; GO:0071005
g1120	147.5837933	-1.483857516	0.375327174	-3.953504083	7.70E-05	0.000513691	58	191	57	46	34	43	427	261	244	349	138	207	sp	Q8HXD5	RN220_MACFA	37.371	388	204	11	379	1494	202	566	1.78E-53	192	Q8HXD5	reviewed	RN220_MACFA	E3 ubiquitin-protein ligase RNF220 (EC 2.3.2.27) (RING finger protein 220) (RING-type E3 ubiquitin transferase RNF220)	RNF220 QflA-23520	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	566	GO:0004842; GO:0005634; GO:0005652; GO:0005737; GO:0008013; GO:0016567; GO:0046872; GO:0051865; GO:0061630; GO:0090263
g17399	54.91201989	-1.616721484	0.525189291	-3.078359578	0.002081436	0.008583313	45	30	72	11	0	19	218	117	72	105	55	54	sp	Q5XGG5	CCNF_XENTR	40.65	615	337	10	52	1866	30	626	2.00E-130	410	Q5XGG5	reviewed	CCNF_XENTR	Cyclin-F	ccnf	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	763	GO:0005634; GO:0005814; GO:0010826; GO:0016567; GO:0019005; GO:0031146; GO:0048471; GO:0051301
g14981	525.0506149	-0.940509067	0.274871151	-3.421636155	0.000622456	0.003073463	325	381	360	479	114	233	1050	685	576	797	1104	814	sp	E9Q4F2	KLH18_MOUSE	60.32	562	223	0	61	1746	10	571	0	745	E9Q4F2	reviewed	KLH18_MOUSE	Kelch-like protein 18	Klhl18	Mus musculus (Mouse)	574	GO:0016567; GO:0051301
g13662	222.3821892	-0.81608183	0.240367571	-3.395141144	0.000685932	0.00334196	238	181	141	128	88	81	424	372	308	375	366	219	sp	Q5ZKD9	KLH20_CHICK	28.788	198	122	4	52	624	58	243	2.63E-10	63.2	Q5ZKD9	reviewed	KLH20_CHICK	Kelch-like protein 20	KLHL20 RCJMB04_11i2	Gallus gallus (Chicken)	610	GO:0005737; GO:0005802; GO:0005829; GO:0006895; GO:0015031; GO:0016567; GO:0016605; GO:0019964; GO:0031463; GO:0043066; GO:0043161; GO:0048471; GO:1990390
g19743	1116.137262	0.952759044	0.352460913	2.703162272	0.006868321	0.022981382	1290	876	911	1031	1865	890	1577	679	606	938	758	933	sp	Q9Y4D8	HECD4_HUMAN	50.113	1325	579	19	4	3870	1752	3030	0	1166	Q9Y4D8	reviewed	HECD4_HUMAN	Probable E3 ubiquitin-protein ligase HECTD4 (EC 2.3.2.26) (HECT domain-containing protein 4) (HECT-type E3 ubiquitin transferase HECTD4)	HECTD4 C12orf51 KIAA0614	Homo sapiens (Human)	3996	GO:0004842; GO:0006006; GO:0016020; GO:0016567; GO:0042593
g12331	3380.53513	1.708649164	0.32408391	5.272243115	1.35E-07	1.97E-06	2429	3898	4363	5998	3191	5840	2407	1646	1187	3840	1067	1295	sp	Q5ZIJ9	MIB2_CHICK	32.716	810	424	18	1	2130	9	797	1.63E-120	387	Q5ZIJ9	reviewed	MIB2_CHICK	E3 ubiquitin-protein ligase MIB2 (EC 2.3.2.27) (Mind bomb homolog 2) (RING-type E3 ubiquitin transferase MIB2)	MIB2 RCJMB04_25j24	Gallus gallus (Chicken)	954	GO:0005737; GO:0007219; GO:0008270; GO:0016567; GO:0061630
g23238	962.960096	1.630713758	0.503644768	3.23782527	0.001204446	0.005434171	1834	2857	1487	200	382	1455	769	486	227	759	458	672	sp	Q4KLT0	RN217_XENLA	42.742	248	133	4	460	1200	3	242	1.77E-59	200	Q4KLT0	reviewed	RN217_XENLA	E3 ubiquitin-protein ligase RNF217 (EC 2.3.2.31) (RING finger protein 217)	rnf217	Xenopus laevis (African clawed frog)	282	GO:0004842; GO:0005737; GO:0008270; GO:0016020; GO:0016567
g23235	206.761389	1.351215405	0.388622629	3.476934445	0.000507182	0.00259253	402	400	506	89	82	224	198	123	127	129	178	53	sp	Q4KLT0	RN217_XENLA	50	148	73	1	622	1062	95	242	2.10E-47	167	Q4KLT0	reviewed	RN217_XENLA	E3 ubiquitin-protein ligase RNF217 (EC 2.3.2.31) (RING finger protein 217)	rnf217	Xenopus laevis (African clawed frog)	282	GO:0004842; GO:0005737; GO:0008270; GO:0016020; GO:0016567
g18476	1034.804131	1.049460667	0.205265285	5.112704124	3.18E-07	4.21E-06	1462	1387	1214	1135	910	1010	987	858	821	927	451	883	sp	Q8QG64	RBX1_SALSA	100	87	0	0	70	330	21	107	3.46E-61	185	Q8QG64	reviewed	RBX1_SALSA	E3 ubiquitin-protein ligase RBX1 (EC 2.3.2.27) (EC 2.3.2.32) (Hyperosmotic protein 21) (sHOP21) (RING-box protein 1) (Rbx1)	rbx1 hop21	Salmo salar (Atlantic salmon)	108	GO:0005634; GO:0005737; GO:0006513; GO:0008270; GO:0016567; GO:0019005; GO:0031146; GO:0031463; GO:0031464; GO:0031465; GO:0031467; GO:0043161; GO:0045116; GO:0061630; GO:0061663; GO:0097602
g18259	3331.6592	-0.933031893	0.39376262	-2.369528865	0.017810765	0.049660704	1687	4403	3773	621	510	2268	8190	6373	4270	4191	3913	4867	sp	Q8WWI1	LMO7_HUMAN	52.941	136	60	1	97	504	74	205	3.63E-34	148	Q8WWI1	reviewed	LMO7_HUMAN	LIM domain only protein 7 (LMO-7) (F-box only protein 20) (LOMP)	LMO7 FBX20 FBXO20 KIAA0858	Homo sapiens (Human)	1683	GO:0000151; GO:0004842; GO:0005634; GO:0005635; GO:0005737; GO:0005829; GO:0005925; GO:0009986; GO:0016324; GO:0016567; GO:0023051; GO:0030155; GO:0045944; GO:0046872
g868	95.07996705	-2.652529822	0.344920309	-7.690268595	1.47E-14	8.89E-13	29	24	37	33	8	10	267	230	150	209	226	122	sp	Q56A24	KLH24_RAT	33.333	567	346	10	97	1779	52	592	8.31E-93	301	Q56A24	reviewed	KLH24_RAT	Kelch-like protein 24 (Kainate receptor-interacting protein for GluR6) (KRIP6) (Protein DRE1)	Klhl24 Dre1	Rattus norvegicus (Rat)	600	GO:0005737; GO:0005912; GO:0016567; GO:0030057; GO:0030424; GO:0031463; GO:0043204; GO:0045109; GO:0051865
g17553	97.40747205	0.791797315	0.313000801	2.529697405	0.011416093	0.034737283	109	145	77	94	93	100	138	93	57	106	93	42	sp	Q8VHQ4	RB40C_MOUSE	69.748	238	66	2	4	714	4	236	2.13E-118	343	Q8VHQ4	reviewed	RB40C_MOUSE	Ras-related protein Rab-40C (SOCS box-containing protein RAR3)	Rab40c	Mus musculus (Mouse)	281	GO:0003924; GO:0005525; GO:0005768; GO:0005794; GO:0005811; GO:0005886; GO:0006887; GO:0008021; GO:0009306; GO:0016567; GO:0019003; GO:0035556; GO:0048471
g17329	411.2786026	1.941384506	0.367403385	5.284068106	1.26E-07	1.86E-06	713	362	416	372	683	565	284	130	173	200	108	324	sp	A9JRZ0	SMUF2_DANRE	67.614	528	105	6	1	1398	242	765	0	733	A9JRZ0	reviewed	SMUF2_DANRE	E3 ubiquitin-protein ligase SMURF2 (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase SMURF2) (SMAD ubiquitination regulatory factor 2) (SMAD-specific E3 ubiquitin-protein ligase 2)	smurf2	Danio rerio (Zebrafish) (Brachydanio rerio)	765	GO:0005634; GO:0005737; GO:0005886; GO:0016567; GO:0030514; GO:0043161; GO:0045121; GO:0046332; GO:0061630
g12959	720.8512633	1.210406015	0.279861594	4.32501652	1.53E-05	0.000127993	948	594	648	919	1081	594	626	400	371	607	616	465	sp	E1C760	UVSSA_CHICK	37.215	790	424	15	73	2415	1	727	3.35E-126	398	E1C760	reviewed	UVSSA_CHICK	UV-stimulated scaffold protein A	UVSSA	Gallus gallus (Chicken)	730	GO:0000993; GO:0005694; GO:0006283; GO:0009411; GO:0016567
g9838	24.87743031	-2.805557503	1.126187245	-2.491199856	0.012731248	0.037930067	36	30	28	0	0	0	67	19	8	48	36	80	sp	Q5R4Q7	LZTR1_PONAB	26.014	296	192	9	4	819	35	327	1.54E-22	107	Q5R4Q7	reviewed	LZTR1_PONAB	Leucine-zipper-like transcriptional regulator 1 (LZTR-1)	LZTR1	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	840	GO:0005794; GO:0012505; GO:0016567; GO:0031267; GO:0031463; GO:0046580; GO:0055038
g14363	1106.996185	0.523139709	0.165755	3.15610214	0.001598929	0.006896728	1327	1043	974	1163	874	1207	1594	1015	1020	1070	866	1071	sp	Q6GPF3	CUL3B_XENLA	78.609	762	150	3	10	2256	7	768	0	1233	Q6GPF3	reviewed	CUL3B_XENLA	Cullin-3-B (CUL-3-B)	cul3b	Xenopus laevis (African clawed frog)	768	GO:0000922; GO:0005634; GO:0005737; GO:0005813; GO:0005827; GO:0006513; GO:0006888; GO:0007080; GO:0007229; GO:0016477; GO:0016567; GO:0017145; GO:0031463; GO:0031625; GO:0035024; GO:0040016; GO:0043149; GO:0043161; GO:0045842; GO:0048208; GO:0072686; GO:1901992
g12243	2089.093271	1.314171175	0.366050297	3.590138256	0.000330503	0.001796327	2956	1572	1911	1429	2886	3563	2180	1432	1491	1461	786	1281	sp	Q5ZIJ9	MIB2_CHICK	47.433	974	413	13	1	2721	9	950	0	879	Q5ZIJ9	reviewed	MIB2_CHICK	E3 ubiquitin-protein ligase MIB2 (EC 2.3.2.27) (Mind bomb homolog 2) (RING-type E3 ubiquitin transferase MIB2)	MIB2 RCJMB04_25j24	Gallus gallus (Chicken)	954	GO:0005737; GO:0007219; GO:0008270; GO:0016567; GO:0061630
g22135	140.3067785	-1.075172698	0.378452567	-2.840970817	0.004497643	0.016293454	61	178	90	90	32	36	385	301	231	279	86	159	sp	Q5R792	ATG5_PONAB	57.554	278	107	4	1	822	1	271	1.71E-116	338	Q5R792	reviewed	ATG5_PONAB	Autophagy protein 5 (APG5-like)	ATG5 APG5L	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	275	GO:0000045; GO:0000423; GO:0001974; GO:0002718; GO:0005776; GO:0005930; GO:0006325; GO:0006914; GO:0006995; GO:0009410; GO:0009620; GO:0010659; GO:0010667; GO:0016567; GO:0019776; GO:0019883; GO:0031397; GO:0032480; GO:0034045; GO:0034274; GO:0035973; GO:0039689; GO:0042311; GO:0044233; GO:0044804; GO:0045060; GO:0045824; GO:0048840; GO:0050687; GO:0050765; GO:0051279; GO:0051649; GO:0055015; GO:0060047; GO:0070254; GO:0070257; GO:0071500; GO:1901096; GO:1902017; GO:1904093; GO:1904973; GO:2000378
g5708	272.533483	1.135847732	0.227500785	4.992720057	5.95E-07	7.36E-06	422	309	271	249	276	351	227	215	185	276	160	171	sp	Q5RB36	CUL5_PONAB	63.322	289	101	3	1	861	1	286	6.03E-118	359	Q5RB36	reviewed	CUL5_PONAB	Cullin-5 (CUL-5)	CUL5	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	780	GO:0005634; GO:0016567; GO:0019005; GO:0031146; GO:0031466; GO:0031625; GO:0038026; GO:0090734; GO:0160072; GO:2001222
g5709	429.9058296	1.309336199	0.257081001	5.093088152	3.52E-07	4.61E-06	636	557	406	373	486	580	371	246	260	381	179	365	sp	Q93034	CUL5_HUMAN	75.456	493	87	3	1	1401	296	780	0	749	Q93034	reviewed	CUL5_HUMAN	Cullin-5 (CUL-5) (Vasopressin-activated calcium-mobilizing receptor 1) (VACM-1)	CUL5 VACM1	Homo sapiens (Human)	780	GO:0000082; GO:0004842; GO:0005262; GO:0005634; GO:0005829; GO:0016567; GO:0019005; GO:0030674; GO:0031146; GO:0031466; GO:0031625; GO:0038023; GO:0038026; GO:0038128; GO:0043161; GO:0070979; GO:0090734; GO:0097193; GO:0160072; GO:2001222
g2272	552.1959476	3.200837109	0.416396779	7.686988151	1.51E-14	9.09E-13	755	610	734	531	1316	587	255	121	82	125	123	80	sp	P56273	MDM2_XENLA	56.364	55	24	0	1885	2049	418	472	5.83E-15	81.6	P56273	reviewed	MDM2_XENLA	E3 ubiquitin-protein ligase Mdm2 (EC 2.3.2.27) (Double minute 2 protein) (Xdm2) (RING-type E3 ubiquitin transferase Mdm2) (p53-binding protein Mdm2)	mdm2	Xenopus laevis (African clawed frog)	473	GO:0002039; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0006915; GO:0010468; GO:0016567; GO:0042802; GO:0043066; GO:0046872; GO:0051726; GO:0061630; GO:0065008
g23737	181.8016563	-1.639814744	0.364726315	-4.496014343	6.92E-06	6.43E-05	67	73	82	150	45	40	455	301	292	224	467	247	sp	E7FDW2	PZR3B_DANRE	35.556	90	57	1	724	990	18	107	2.80E-09	63.9	E7FDW2	reviewed	PZR3B_DANRE	E3 ubiquitin-protein ligase PDZRN3-B (EC 2.3.2.27) (PDZ domain-containing RING finger protein 3-B)	pdzrn3b pdzrn3	Danio rerio (Zebrafish) (Brachydanio rerio)	1053	GO:0005737; GO:0007528; GO:0016567; GO:0045202; GO:0046872; GO:0061630
g19074	163.8212835	-0.707101064	0.240180213	-2.944043788	0.003239542	0.012382854	116	137	98	166	53	80	370	228	196	249	258	199	sp	Q9UJX3	APC7_HUMAN	46.986	564	292	4	4	1677	1	563	2.51E-158	467	Q9UJX3	reviewed	APC7_HUMAN	Anaphase-promoting complex subunit 7 (APC7) (Cyclosome subunit 7)	ANAPC7 APC7	Homo sapiens (Human)	565	GO:0000792; GO:0005634; GO:0005654; GO:0005680; GO:0005819; GO:0005829; GO:0007346; GO:0007420; GO:0015630; GO:0016567; GO:0019903; GO:0031145; GO:0045842; GO:0051301; GO:0051445; GO:0070936; GO:0070979; GO:0140767; GO:0141198
g21625	902.4658489	1.119447739	0.233674851	4.790621395	1.66E-06	1.83E-05	1103	839	997	876	1040	1212	902	525	721	691	652	580	sp	Q71U00	SKP1_XENLA	84.049	163	25	1	1	486	1	163	1.13E-79	236	Q71U00	reviewed	SKP1_XENLA	S-phase kinase-associated protein 1 (Cyclin-A/CDK2-associated protein p19) (S-phase kinase-associated protein 1A) (p19A) (p19skp1)	skp1 skp1a	Xenopus laevis (African clawed frog)	163	GO:0005634; GO:0005737; GO:0016567; GO:0019005; GO:0031146; GO:0031467; GO:0097602
g10609	498.3887247	-0.910502216	0.26024664	-3.498612764	0.000467685	0.00241689	359	445	312	391	156	166	1312	892	611	915	699	458	sp	Q91ZT9	ASB8_MOUSE	52.107	261	124	1	4	786	3	262	9.87E-98	291	Q91ZT9	reviewed	ASB8_MOUSE	Ankyrin repeat and SOCS box protein 8 (ASB-8)	Asb8	Mus musculus (Mouse)	288	GO:0005737; GO:0016567; GO:0035556
g21796	14396.64259	0.644495968	0.192959177	3.340063821	0.000837591	0.003959064	15319	16370	13476	15278	12501	14943	14954	11878	12627	12369	16899	11332	sp	P63245	RACK1_RAT	80.769	312	60	0	1	936	1	312	0	540	P63245	reviewed	RACK1_RAT	"Small ribosomal subunit protein RACK1 (Guanine nucleotide-binding protein subunit beta-2-like 1) (Receptor for activated C kinase) (Receptor of activated protein C kinase 1) (Receptor of activated protein kinase C 1) [Cleaved into: Small ribosomal subunit protein RACK1, N-terminally processed (Receptor of activated protein C kinase 1, N-terminally processed)]"	Rack1 Gnb2l1	Rattus norvegicus (Rat)	317	GO:0001649; GO:0001891; GO:0001934; GO:0005080; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0006412; GO:0007205; GO:0007369; GO:0008047; GO:0008200; GO:0008656; GO:0010629; GO:0015935; GO:0016020; GO:0016567; GO:0017148; GO:0019899; GO:0019903; GO:0030178; GO:0030292; GO:0030308; GO:0030332; GO:0030335; GO:0030425; GO:0030496; GO:0030971; GO:0031334; GO:0032436; GO:0032880; GO:0033137; GO:0035591; GO:0042169; GO:0042803; GO:0042998; GO:0043005; GO:0043022; GO:0043025; GO:0043065; GO:0043204; GO:0043473; GO:0043547; GO:0044297; GO:0045182; GO:0045879; GO:0048471; GO:0048511; GO:0050765; GO:0051302; GO:0051434; GO:0051726; GO:0051898; GO:0051901; GO:0071333; GO:0071363; GO:0072344; GO:0106070; GO:1903076; GO:1903751; GO:1990630; GO:2000114; GO:2000543; GO:2001244
g23854	60.92048869	-2.200595436	0.609450291	-3.610787406	0.000305269	0.00168195	0	35	21	23	7	27	181	91	105	135	132	94	sp	Q9R1A8	COP1_MOUSE	52.924	342	132	9	100	1092	123	446	6.47E-111	343	Q9R1A8	reviewed	COP1_MOUSE	E3 ubiquitin-protein ligase COP1 (EC 2.3.2.27) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1) (RING finger and WD repeat domain protein 2) (RING-type E3 ubiquitin transferase RFWD2)	Cop1 Rfwd2 RNF200	Mus musculus (Mouse)	733	GO:0000139; GO:0010212; GO:0016567; GO:0016607; GO:0031464; GO:0032436; GO:0043161; GO:0046872; GO:0061630
g23853	54.23902331	-2.173239229	0.386665791	-5.62045901	1.90E-08	3.43E-07	25	17	7	31	8	15	187	76	79	97	130	91	sp	Q9R1A8	COP1_MOUSE	76.981	265	57	1	1	783	469	733	6.45E-148	434	Q9R1A8	reviewed	COP1_MOUSE	E3 ubiquitin-protein ligase COP1 (EC 2.3.2.27) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1) (RING finger and WD repeat domain protein 2) (RING-type E3 ubiquitin transferase RFWD2)	Cop1 Rfwd2 RNF200	Mus musculus (Mouse)	733	GO:0000139; GO:0010212; GO:0016567; GO:0016607; GO:0031464; GO:0032436; GO:0043161; GO:0046872; GO:0061630
g16921	661.5093978	1.592869057	0.354675166	4.491064523	7.09E-06	6.56E-05	1127	925	627	1107	616	658	880	333	294	579	133	343	sp	Q8LEV3	Y2060_ARATH	23.108	251	142	9	145	807	344	573	2.63E-07	57	Q8LEV3	reviewed	Y2060_ARATH	BTB/POZ domain-containing protein At2g30600	At2g30600/At2g30610 T6B20.5/T6B20.4	Arabidopsis thaliana (Mouse-ear cress)	809	GO:0016567
g19889	473.7226721	1.486391408	0.357020149	4.163326391	3.14E-05	0.000239563	702	421	424	350	784	613	328	185	303	428	184	340	sp	A5HK05	APBP2_RAT	67.826	575	183	1	10	1734	3	575	0	808	A5HK05	reviewed	APBP2_RAT	Amyloid protein-binding protein 2 (Amyloid beta precursor protein-binding protein 2) (APP-BP2)	Appbp2	Rattus norvegicus (Rat)	585	GO:0005654; GO:0005874; GO:0006886; GO:0016567; GO:0030659; GO:0031462; GO:0043161; GO:0046907; GO:1990756
g4112	67.42908798	-1.234232815	0.378518428	-3.260694131	0.001111399	0.005067343	55	30	67	29	20	18	163	116	93	157	41	133	sp	Q5F4A1	G2E3_CHICK	43.871	310	169	3	31	957	6	311	2.40E-77	276	Q5F4A1	reviewed	G2E3_CHICK	G2/M phase-specific E3 ubiquitin-protein ligase (EC 2.3.2.26) (G2/M phase-specific HECT-type E3 ubiquitin transferase)	G2E3 RCJMB04_1m6	Gallus gallus (Chicken)	742	GO:0004842; GO:0005634; GO:0005730; GO:0005737; GO:0006915; GO:0016567; GO:0046872
g133	50.07800856	5.235055115	1.161331784	4.507803187	6.55E-06	6.13E-05	12	212	142	4	0	168	5	8	10	2	0	1	sp	Q9R1R2	TRIM3_MOUSE	30	180	122	2	16	549	7	184	9.52E-21	97.4	Q9R1R2	reviewed	TRIM3_MOUSE	Tripartite motif-containing protein 3 (EC 2.3.2.27) (RING finger protein 22) (RING finger protein HAC1)	Trim3 Hac1 Rnf22	Mus musculus (Mouse)	744	GO:0000209; GO:0004842; GO:0005737; GO:0005769; GO:0005794; GO:0008270; GO:0015031; GO:0016567; GO:0017148; GO:0030371; GO:0030425; GO:0034141; GO:0042802; GO:0043161; GO:0061630; GO:0070534; GO:0098794; GO:0098978; GO:0140252
g16370	147.1775256	-1.913180402	0.436249606	-4.385517777	1.16E-05	0.000100523	94	102	68	62	23	7	416	243	228	226	300	278	sp	Q922Y2	TRI59_MOUSE	34.118	85	47	3	64	297	6	88	2.26E-09	63.2	Q922Y2	reviewed	TRI59_MOUSE	Tripartite motif-containing protein 59 (EC 2.3.2.27) (RING finger protein 1)	Trim59 Mrf1	Mus musculus (Mouse)	403	GO:0005783; GO:0005789; GO:0008270; GO:0016567; GO:0043124; GO:0045087; GO:0046597; GO:0061630
g13099	362.1334854	-1.216828417	0.387771119	-3.138006822	0.001701009	0.007246501	180	162	292	283	96	93	584	531	322	506	1150	526	sp	Q7L273	KCTD9_HUMAN	58.647	399	155	2	1	1197	1	389	1.36E-166	475	Q7L273	reviewed	KCTD9_HUMAN	BTB/POZ domain-containing protein KCTD9	KCTD9	Homo sapiens (Human)	389	GO:0016567; GO:0035556; GO:0042802; GO:0051260; GO:0097602
g5940	147.6415133	-0.762669488	0.271109749	-2.813139293	0.004906039	0.01751925	153	133	75	74	64	73	292	186	190	162	256	260	sp	Q58WW2	DCAF6_HUMAN	72.263	137	37	1	1264	1671	703	839	6.36E-61	219	Q58WW2	reviewed	DCAF6_HUMAN	DDB1- and CUL4-associated factor 6 (Androgen receptor complex-associated protein) (ARCAP) (IQ motif and WD repeat-containing protein 1) (Nuclear receptor interaction protein) (NRIP)	DCAF6 IQWD1 MSTP055	Homo sapiens (Human)	860	GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005925; GO:0016567; GO:0030374; GO:0045944; GO:0080008
g5941	83.98346155	-0.803661338	0.240695816	-3.338908633	0.000841082	0.003969044	62	43	71	63	31	47	183	116	145	127	82	133	sp	Q58WW2	DCAF6_HUMAN	57.66	359	130	4	34	1092	15	357	4.88E-143	432	Q58WW2	reviewed	DCAF6_HUMAN	DDB1- and CUL4-associated factor 6 (Androgen receptor complex-associated protein) (ARCAP) (IQ motif and WD repeat-containing protein 1) (Nuclear receptor interaction protein) (NRIP)	DCAF6 IQWD1 MSTP055	Homo sapiens (Human)	860	GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005925; GO:0016567; GO:0030374; GO:0045944; GO:0080008
g2521	1874.745592	0.794435836	0.252067479	3.151679223	0.001623345	0.006975898	2230	1845	1690	1610	2162	2077	2685	1333	1276	2219	1181	1446	sp	Q8BZZ3	WWP1_MOUSE	66.667	582	176	5	1060	2763	341	918	0	786	Q8BZZ3	reviewed	WWP1_MOUSE	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase WWP1) (WW domain-containing protein 1)	Wwp1	Mus musculus (Mouse)	918	GO:0004842; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0016567; GO:0030217; GO:0030324; GO:0043161; GO:0045892; GO:0061630
g3579	456.110384	-0.511663796	0.145318177	-3.520989649	0.000429939	0.002248293	387	376	374	388	146	308	846	605	536	733	586	630	sp	Q80T85	DCAF5_MOUSE	59.277	415	160	2	13	1230	13	427	6.43E-164	504	Q80T85	reviewed	DCAF5_MOUSE	DDB1- and CUL4-associated factor 5 (WD repeat-containing protein 22)	Dcaf5 Kiaa1824 Wdr22	Mus musculus (Mouse)	946	GO:0005737; GO:0005739; GO:0016567; GO:0045717; GO:0080008
g17771	341.6857397	1.027046623	0.270481723	3.797101748	0.000146398	0.000897733	502	350	404	218	378	425	410	269	242	225	255	248	sp	Q969H0	FBXW7_HUMAN	64.236	288	88	5	847	1707	195	468	9.88E-119	370	Q969H0	reviewed	FBXW7_HUMAN	F-box/WD repeat-containing protein 7 (Archipelago homolog) (hAgo) (F-box and WD-40 domain-containing protein 7) (F-box protein FBX30) (SEL-10) (hCdc4)	FBXW7 FBW7 FBX30 SEL10	Homo sapiens (Human)	707	GO:0001570; GO:0001944; GO:0005634; GO:0005654; GO:0005694; GO:0005730; GO:0005737; GO:0005739; GO:0005783; GO:0005794; GO:0005829; GO:0006281; GO:0006974; GO:0007062; GO:0007219; GO:0010629; GO:0010868; GO:0010883; GO:0010992; GO:0016567; GO:0019005; GO:0030324; GO:0030332; GO:0030674; GO:0031146; GO:0031398; GO:0031625; GO:0031648; GO:0032880; GO:0032991; GO:0034644; GO:0042752; GO:0042802; GO:0043130; GO:0043161; GO:0045741; GO:0045746; GO:0048471; GO:0048511; GO:0050816; GO:0050821; GO:0051443; GO:0055088; GO:0070374; GO:0090049; GO:0097027; GO:1901524; GO:1901800; GO:1902806; GO:1903378; GO:1903955; GO:1990452; GO:1990756; GO:2000060; GO:2000346; GO:2000639; GO:2001205
g17770	148.0885597	1.180063734	0.332409529	3.550029805	0.000385188	0.002045788	246	166	120	119	186	169	152	72	87	146	144	63	sp	Q969H0	FBXW7_HUMAN	89.048	210	23	0	1	630	498	707	9.52E-126	374	Q969H0	reviewed	FBXW7_HUMAN	F-box/WD repeat-containing protein 7 (Archipelago homolog) (hAgo) (F-box and WD-40 domain-containing protein 7) (F-box protein FBX30) (SEL-10) (hCdc4)	FBXW7 FBW7 FBX30 SEL10	Homo sapiens (Human)	707	GO:0001570; GO:0001944; GO:0005634; GO:0005654; GO:0005694; GO:0005730; GO:0005737; GO:0005739; GO:0005783; GO:0005794; GO:0005829; GO:0006281; GO:0006974; GO:0007062; GO:0007219; GO:0010629; GO:0010868; GO:0010883; GO:0010992; GO:0016567; GO:0019005; GO:0030324; GO:0030332; GO:0030674; GO:0031146; GO:0031398; GO:0031625; GO:0031648; GO:0032880; GO:0032991; GO:0034644; GO:0042752; GO:0042802; GO:0043130; GO:0043161; GO:0045741; GO:0045746; GO:0048471; GO:0048511; GO:0050816; GO:0050821; GO:0051443; GO:0055088; GO:0070374; GO:0090049; GO:0097027; GO:1901524; GO:1901800; GO:1902806; GO:1903378; GO:1903955; GO:1990452; GO:1990756; GO:2000060; GO:2000346; GO:2000639; GO:2001205
g12615	77.89151427	-1.049825771	0.332456472	-3.157784128	0.001589732	0.006867357	37	87	43	49	13	43	193	115	84	135	144	108	sp	Q0IJ33	TM129_XENTR	50.833	360	175	2	13	1089	3	361	5.30E-129	377	Q0IJ33	reviewed	TM129_XENTR	E3 ubiquitin-protein ligase TM129 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TM129)	tmem129	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	362	GO:0005789; GO:0006986; GO:0016567; GO:0046872; GO:0061630
g4518	351.5925675	-1.056531152	0.353384204	-2.989752062	0.00279204	0.010976131	185	376	329	195	80	97	882	477	293	842	422	625	sp	Q8N806	UBR7_HUMAN	45.575	452	180	9	43	1383	34	424	7.24E-118	355	Q8N806	reviewed	UBR7_HUMAN	Putative E3 ubiquitin-protein ligase UBR7 (EC 2.3.2.27) (N-recognin-7) (RING-type E3 ubiquitin transferase UBR7)	UBR7 C14orf130	Homo sapiens (Human)	425	GO:0008270; GO:0016567; GO:0061630
g13047	75.5746825	-1.776374418	0.631528446	-2.812817745	0.004910948	0.017529524	50	72	47	32	0	15	245	114	76	265	64	114	sp	Q8BGZ4	CDC23_MOUSE	56.971	581	232	6	40	1761	28	597	0	674	Q8BGZ4	reviewed	CDC23_MOUSE	Cell division cycle protein 23 homolog (Anaphase-promoting complex subunit 8) (APC8) (Cyclosome subunit 8)	Cdc23 Anapc8	Mus musculus (Mouse)	597	GO:0005680; GO:0016567; GO:0031145; GO:0045842; GO:0051301; GO:0070936; GO:0070979; GO:0141198
g22310	149.1278087	2.248612362	0.355266733	6.329363688	2.46E-10	6.83E-09	332	187	186	153	189	194	127	56	27	39	68	73	sp	Q6GPV5	RN181_XENLA	50.307	163	65	5	1	462	1	156	2.87E-47	153	Q6GPV5	reviewed	RN181_XENLA	E3 ubiquitin-protein ligase RNF181 (EC 2.3.2.27) (RING finger protein 181)	rnf181	Xenopus laevis (African clawed frog)	156	GO:0016567; GO:0046872; GO:0061630
g4123	10805.53159	1.018865102	0.230654376	4.417280598	1.00E-05	8.87E-05	12889	13308	8617	12299	11695	12635	10741	7829	8385	8468	5972	9771	sp	P79781	RS27A_CHICK	96.032	126	5	0	1	378	1	126	5.72E-58	179	P79781	reviewed	RS27A_CHICK	Ubiquitin-ribosomal protein eS31 fusion protein (Ubiquitin carboxyl extension protein 80) [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31 (40S ribosomal protein S27a)]	RPS27A UBA80	Gallus gallus (Chicken)	156	GO:0003735; GO:0005654; GO:0005730; GO:0006412; GO:0016567; GO:0019941; GO:0022627; GO:0031386; GO:0031625; GO:0032040; GO:0042274; GO:0046872
g16369	347.689685	-1.668533181	0.314992361	-5.297059188	1.18E-07	1.75E-06	153	107	175	189	100	127	773	745	458	1027	260	648	sp	Q5PQN5	TRI55_RAT	37.778	90	45	3	88	327	26	114	5.93E-10	62.4	Q5PQN5	reviewed	TRI55_RAT	Tripartite motif-containing protein 55 (EC 2.3.2.27) (Muscle-specific RING finger protein 2) (MuRF-2) (MuRF2) (RING finger protein 29)	Trim55 Murf2 Rnf29	Rattus norvegicus (Rat)	545	GO:0002523; GO:0005634; GO:0005737; GO:0008270; GO:0016567; GO:0030674; GO:0042802; GO:0050904; GO:0061630; GO:0070936; GO:1901224; GO:1905517
g14918	146.4250279	-1.072792689	0.291375155	-3.681826225	0.000231569	0.00132626	81	115	139	94	28	57	322	204	256	261	136	278	sp	Q6DG60	UBE2Z_DANRE	67.568	259	82	2	28	801	42	299	4.98E-129	373	Q6DG60	reviewed	UBE2Z_DANRE	Ubiquitin-conjugating enzyme E2 Z (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme Z) (Ubiquitin carrier protein Z) (Ubiquitin-protein ligase Z)	ube2z zgc:92419	Danio rerio (Zebrafish) (Brachydanio rerio)	328	GO:0004869; GO:0005524; GO:0005634; GO:0005737; GO:0006915; GO:0016567; GO:0043066; GO:0061631
g8817	807.0462259	1.533458162	0.337960231	4.537392334	5.70E-06	5.43E-05	1351	633	803	655	894	1601	675	623	433	583	329	354	sp	P0CG73	UBI1P_CANAX	27.632	152	104	2	7	462	1	146	3.45E-09	60.8	P0CG73	reviewed	UBI1P_CANAX	Polyubiquitin [Cleaved into: Ubiquitin-related; Ubiquitin]	UBI1	Candida albicans (Yeast)	229	GO:0005634; GO:0005737; GO:0016567; GO:0019941; GO:0031386; GO:0031625
g8818	2790.077934	3.681495609	0.47915359	7.683330949	1.55E-14	9.32E-13	6741	956	3005	1830	4459	7908	553	401	352	362	561	529	sp	P0CG73	UBI1P_CANAX	26.364	110	81	0	7	336	1	110	4.33E-07	54.7	P0CG73	reviewed	UBI1P_CANAX	Polyubiquitin [Cleaved into: Ubiquitin-related; Ubiquitin]	UBI1	Candida albicans (Yeast)	229	GO:0005634; GO:0005737; GO:0016567; GO:0019941; GO:0031386; GO:0031625
g8225	1289.35994	-0.416741571	0.1677232	-2.484698429	0.012966122	0.038450645	1437	1099	921	909	630	734	2261	1372	1569	1864	1921	1765	sp	Q9P1Y6	PHRF1_HUMAN	52.217	203	85	5	385	966	106	305	3.30E-56	221	Q9P1Y6	reviewed	PHRF1_HUMAN	PHD and RING finger domain-containing protein 1	PHRF1 KIAA1542	Homo sapiens (Human)	1649	GO:0016020; GO:0016567; GO:0046872; GO:0070063
g14385	4885.205629	1.328075322	0.257196248	5.163665227	2.42E-07	3.33E-06	7962	4870	4678	5090	5748	6201	6015	2643	2526	4030	2234	3310	sp	Q93008	USP9X_HUMAN	69.167	2400	690	17	220	7287	102	2495	0	3260	Q93008	reviewed	USP9X_HUMAN	"Ubiquitin carboxyl-terminal hydrolase 9X (EC 3.4.19.12) (Deubiquitinating enzyme FAF-X) (Fat facets in mammals) (hFAM) (Fat facets protein-related, X-linked) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin-specific-processing protease FAF-X)"	USP9X DFFRX FAM USP9	Homo sapiens (Human)	2554	GO:0000122; GO:0001764; GO:0004197; GO:0004843; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0005929; GO:0006307; GO:0007059; GO:0007179; GO:0007292; GO:0008104; GO:0008234; GO:0016020; GO:0016477; GO:0016562; GO:0016567; GO:0016579; GO:0030426; GO:0030509; GO:0032092; GO:0032435; GO:0035520; GO:0042752; GO:0048511; GO:0048675; GO:0050821; GO:0051301; GO:0060271; GO:0061578; GO:0061824; GO:0070410; GO:0070536; GO:0071947; GO:0101005; GO:0140313; GO:0180017; GO:1904515; GO:1990000; GO:1990380
g15387	822.5971559	1.310354415	0.21186799	6.184768237	6.22E-10	1.58E-08	1026	1135	887	1132	685	1085	736	495	451	437	785	493	sp	Q5FVN8	WSDU1_RAT	40.726	496	255	10	1	1452	1	469	1.63E-115	351	Q5FVN8	reviewed	WSDU1_RAT	"WD repeat, SAM and U-box domain-containing protein 1"	Wdsub1	Rattus norvegicus (Rat)	476	GO:0004842; GO:0016567
g3688	4634.457306	1.784157804	0.343798913	5.189538819	2.11E-07	2.94E-06	8866	6581	5008	2711	6293	6151	4738	1974	1743	3116	1454	2810	sp	Q9NR09	BIRC6_HUMAN	46.802	1970	850	38	9298	14973	3001	4850	0	1368	Q9NR09	reviewed	BIRC6_HUMAN	Baculoviral IAP repeat-containing protein 6 (EC 2.3.2.27) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (RING-type E3 ubiquitin transferase BIRC6) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON)	BIRC6 KIAA1289	Homo sapiens (Human)	4857	GO:0000922; GO:0004842; GO:0004869; GO:0005634; GO:0005768; GO:0005802; GO:0005813; GO:0005815; GO:0005829; GO:0006468; GO:0006915; GO:0008283; GO:0008284; GO:0016020; GO:0016567; GO:0030496; GO:0032465; GO:0042127; GO:0043066; GO:0051301; GO:0060711; GO:0060712; GO:0061631; GO:0090543; GO:2001237
g1447	15111.59746	1.591487111	0.293736383	5.418079631	6.02E-08	9.65E-07	23115	14364	14613	18800	20762	18543	9586	6852	9186	7080	12576	7029	sp	P23787	TERA_XENLA	87.223	767	96	2	2155	4455	10	774	0	1330	P23787	reviewed	TERA_XENLA	Transitional endoplasmic reticulum ATPase (TER ATPase) (EC 3.6.4.6) (15S Mg(2+)-ATPase p97 subunit) (p97) (Valosin-containing protein) (VCP)	vcp	Xenopus laevis (African clawed frog)	805	GO:0000785; GO:0005524; GO:0005634; GO:0005737; GO:0005783; GO:0005829; GO:0006281; GO:0006302; GO:0006914; GO:0006974; GO:0008289; GO:0010494; GO:0010498; GO:0016236; GO:0016567; GO:0016887; GO:0019985; GO:0032510; GO:0034605; GO:0035617; GO:0035861; GO:0036297; GO:0036503; GO:0042802; GO:0043161; GO:0044877; GO:0061857; GO:0097352; GO:1903843; GO:1905634
g20104	335.7654232	0.759481768	0.2290122	3.316337595	0.000912056	0.004257411	588	419	400	388	207	235	344	262	416	267	257	253	sp	Q9UHC7	MKRN1_HUMAN	50.877	57	27	1	94	261	55	111	4.39E-16	77.8	Q9UHC7	reviewed	MKRN1_HUMAN	E3 ubiquitin-protein ligase makorin-1 (EC 2.3.2.27) (RING finger protein 61) (RING-type E3 ubiquitin transferase makorin-1)	MKRN1 RNF61	Homo sapiens (Human)	482	GO:0000209; GO:0003723; GO:0005829; GO:0016567; GO:0046872; GO:0061630
g5023	55.51444145	-1.762532666	0.506876831	-3.477240544	0.000506603	0.002590338	38	3	15	41	11	26	125	107	98	146	85	62	sp	Q8WV16	DCAF4_HUMAN	48.341	211	104	4	517	1140	284	492	3.68E-56	194	Q8WV16	reviewed	DCAF4_HUMAN	DDB1- and CUL4-associated factor 4 (WD repeat-containing protein 21A)	DCAF4 WDR21 WDR21A	Homo sapiens (Human)	495	GO:0005654; GO:0016567; GO:0080008
g937	204.318204	-1.201762946	0.394273379	-3.048044864	0.002303355	0.009351016	136	56	171	196	37	61	494	427	326	400	199	274	sp	Q3SZD5	DCA15_BOVIN	36.765	272	120	9	67	846	35	266	5.54E-34	142	Q3SZD5	reviewed	DCA15_BOVIN	DDB1- and CUL4-associated factor 15	DCAF15	Bos taurus (Bovine)	600	GO:0000209; GO:0002376; GO:0016567; GO:0032814; GO:0046872; GO:0080008
g17977	527.4091925	2.187955348	0.301271653	7.26240031	3.80E-13	1.76E-11	805	565	556	807	842	582	292	221	212	151	203	250	sp	Q9Z255	UBE2A_MOUSE	92.617	149	11	0	1	447	1	149	2.80E-102	292	Q9Z255	reviewed	UBE2A_MOUSE	Ubiquitin-conjugating enzyme E2 A (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme A) (RAD6 homolog A) (HR6A) (mHR6A) (Ubiquitin carrier protein A) (Ubiquitin-protein ligase A)	Ube2a Rad6a	Mus musculus (Mouse)	152	GO:0000209; GO:0000785; GO:0001701; GO:0001741; GO:0001835; GO:0004842; GO:0005524; GO:0005764; GO:0005770; GO:0006281; GO:0016567; GO:0031625; GO:0033503; GO:0043161; GO:0060135; GO:0061631; GO:0070936; GO:0070979; GO:1901526
g15228	23.81819879	-4.77782262	0.892293856	-5.354539416	8.58E-08	1.32E-06	0	8	5	0	0	0	67	61	44	58	61	40	sp	E1BNS0	FXL15_BOVIN	28.125	256	154	4	34	717	21	274	1.61E-22	96.7	E1BNS0	reviewed	FXL15_BOVIN	F-box/LRR-repeat protein 15	FBXL15	Bos taurus (Bovine)	300	GO:0000086; GO:0005737; GO:0009953; GO:0016567; GO:0019005; GO:0030282; GO:0030513; GO:0031146
g3724	27.18045727	-5.319319532	1.254855318	-4.238990308	2.25E-05	0.00017869	14	0	0	0	0	0	65	67	74	50	102	13	sp	Q7L622	G2E3_HUMAN	32.057	209	126	6	1	615	425	621	5.43E-27	111	Q7L622	reviewed	G2E3_HUMAN	G2/M phase-specific E3 ubiquitin-protein ligase (EC 2.3.2.26) (G2/M phase-specific HECT-type E3 ubiquitin transferase)	G2E3 KIAA1333	Homo sapiens (Human)	706	GO:0004842; GO:0005634; GO:0005730; GO:0005794; GO:0005829; GO:0006915; GO:0016567; GO:0043231; GO:0046872
g1596	109.865299	-1.432416691	0.313986105	-4.562038471	5.07E-06	4.90E-05	53	60	51	91	15	40	216	123	164	230	230	201	sp	Q9NXK8	FXL12_HUMAN	29.778	225	154	2	10	681	7	228	2.48E-30	120	Q9NXK8	reviewed	FXL12_HUMAN	F-box/LRR-repeat protein 12 (F-box and leucine-rich repeat protein 12) (F-box protein FBL12)	FBXL12 FBL12	Homo sapiens (Human)	326	GO:0005829; GO:0016567; GO:0019005; GO:0031146
g16626	35.97481302	-1.716348972	0.616314892	-2.784857212	0.00535513	0.018803957	12	38	29	8	0	14	77	53	37	63	99	63	sp	B5DF45	TRAF6_RAT	31.95	482	278	16	19	1359	41	507	2.70E-63	216	B5DF45	reviewed	TRAF6_RAT	TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6)	Traf6	Rattus norvegicus (Rat)	530	GO:0000045; GO:0000122; GO:0000209; GO:0001503; GO:0001701; GO:0001843; GO:0002637; GO:0002726; GO:0002753; GO:0002931; GO:0004842; GO:0005164; GO:0005634; GO:0005737; GO:0005811; GO:0005829; GO:0005886; GO:0005938; GO:0006955; GO:0006974; GO:0007165; GO:0007249; GO:0007254; GO:0007416; GO:0008270; GO:0009887; GO:0009898; GO:0016567; GO:0019221; GO:0019886; GO:0030316; GO:0031234; GO:0031624; GO:0031663; GO:0031666; GO:0032481; GO:0032735; GO:0032743; GO:0032755; GO:0032991; GO:0033209; GO:0034142; GO:0034450; GO:0035631; GO:0038061; GO:0038172; GO:0038173; GO:0042088; GO:0042102; GO:0042475; GO:0042802; GO:0042826; GO:0042981; GO:0043011; GO:0043122; GO:0043123; GO:0043422; GO:0045087; GO:0045453; GO:0045672; GO:0045892; GO:0045944; GO:0046849; GO:0048468; GO:0048471; GO:0048661; GO:0050852; GO:0051092; GO:0051865; GO:0061630; GO:0070301; GO:0070498; GO:0070534; GO:0070555; GO:0071222; GO:0071345; GO:0097400; GO:0098696; GO:0098794; GO:0098978; GO:0140252; GO:0140374; GO:1904385; GO:1904996
g2128	1354.912744	1.406386464	0.347969374	4.041696108	5.31E-05	0.000370678	1736	1475	1541	1095	1963	1616	1739	857	946	998	415	676	sp	Q5RCM6	SOCS6_PONAB	58.788	165	64	2	1048	1530	371	535	1.15E-55	198	Q5RCM6	reviewed	SOCS6_PONAB	Suppressor of cytokine signaling 6 (SOCS-6)	SOCS6	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	535	GO:0001772; GO:0005942; GO:0009968; GO:0010498; GO:0016567; GO:0035556; GO:0040008; GO:0046854; GO:0046935; GO:0050868
g4603	206.7239938	-1.380288676	0.3358982	-4.109247015	3.97E-05	0.000290716	162	120	95	98	70	42	517	228	188	443	495	343	sp	Q5BJN8	SDE2_RAT	33.019	212	117	3	4	564	4	215	1.02E-25	110	Q5BJN8	reviewed	SDE2_RAT	UBL fusion protein SDE2 (Replication stress response regulator SDE2)	Sde2	Rattus norvegicus (Rat)	448	GO:0000479; GO:0003684; GO:0005634; GO:0005737; GO:0006260; GO:0016485; GO:0016567; GO:0030515; GO:0031571; GO:0034644; GO:0045292; GO:0051301
g17258	2817.806859	4.955655108	0.638765682	7.758173687	8.62E-15	5.39E-13	4311	4274	3136	1312	6449	5682	221	172	258	31	421	67	sp	O35717	SOCS2_MOUSE	40.741	189	85	3	166	732	35	196	3.29E-35	127	O35717	reviewed	SOCS2_MOUSE	Suppressor of cytokine signaling 2 (SOCS-2)	Socs2	Mus musculus (Mouse)	198	GO:0005131; GO:0005159; GO:0005737; GO:0005942; GO:0007259; GO:0007595; GO:0016567; GO:0031466; GO:0032355; GO:0035556; GO:0040014; GO:0040015; GO:0043161; GO:0045666; GO:0046426; GO:0046854; GO:0046935; GO:0060396; GO:0060400; GO:0060749; GO:0140031; GO:1990756
g12377	37.2832431	-1.611221857	0.467166608	-3.448923421	0.000562826	0.002834162	28	6	13	30	4	17	111	88	47	62	59	52	sp	Q6TDP4	KLH17_HUMAN	63.492	63	23	0	1	189	563	625	1.12E-21	90.1	Q6TDP4	reviewed	KLH17_HUMAN	Kelch-like protein 17 (Actinfilin)	KLHL17 AF	Homo sapiens (Human)	642	GO:0005615; GO:0014069; GO:0015629; GO:0016567; GO:0030036; GO:0031208; GO:0032839; GO:0043025; GO:0051015; GO:0060090; GO:0098978; GO:0140252
g12378	267.7256701	-1.49866384	0.405180172	-3.698759084	0.000216656	0.001255006	137	134	104	247	24	106	613	491	442	383	615	315	sp	Q8K430	KLH17_RAT	61.585	492	186	1	61	1536	47	535	0	613	Q8K430	reviewed	KLH17_RAT	Kelch-like protein 17 (Actinfilin)	Klhl17	Rattus norvegicus (Rat)	640	GO:0014069; GO:0015629; GO:0016567; GO:0030036; GO:0031208; GO:0032839; GO:0043025; GO:0051015; GO:0060090; GO:0098794; GO:0098978; GO:0140252
g23275	74.49654921	3.270202822	0.684026849	4.780810616	1.75E-06	1.91E-05	204	410	82	15	22	71	22	8	8	6	11	28	sp	Q5UQ88	UBC3_MIMIV	35.052	194	120	4	216	779	375	568	2.13E-14	79.3	Q5UQ88	reviewed	UBC3_MIMIV	Probable ubiquitin-conjugating enzyme E2 R521 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme R521) (Ubiquitin carrier protein) (Ubiquitin-protein ligase)	MIMI_R521	Acanthamoeba polyphaga mimivirus (APMV)	1441	GO:0005524; GO:0016020; GO:0016567; GO:0042262; GO:0061631
g13272	388.8427373	1.326186059	0.465732898	2.847524975	0.004406064	0.016025594	697	823	460	80	251	661	499	217	138	206	282	314	sp	Q8BI21	RNF38_MOUSE	76.316	114	25	1	1084	1425	353	464	1.27E-50	182	Q8BI21	reviewed	RNF38_MOUSE	E3 ubiquitin-protein ligase RNF38 (EC 2.3.2.27) (RING finger protein 38) (RING-type E3 ubiquitin transferase RNF38)	Rnf38	Mus musculus (Mouse)	464	GO:0005654; GO:0016567; GO:0036126; GO:0046872; GO:0061630
g6777	283.8936836	-1.551074224	0.303934748	-5.103313248	3.34E-07	4.40E-06	109	172	164	115	71	121	1083	377	283	800	322	422	sp	Q5XI67	FBX30_RAT	45.614	171	81	3	292	771	4	173	1.12E-37	155	Q5XI67	reviewed	FBX30_RAT	F-box only protein 30	Fbxo30	Rattus norvegicus (Rat)	742	GO:0008270; GO:0016567; GO:0061630
g11425	480.1415288	0.533330436	0.212850278	2.505660034	0.012222307	0.036730757	678	481	472	431	392	425	858	394	521	469	366	347	sp	A2A6Q5	CDC27_MOUSE	53.584	851	357	13	4	2529	3	824	0	892	A2A6Q5	reviewed	CDC27_MOUSE	Cell division cycle protein 27 homolog	Cdc27	Mus musculus (Mouse)	825	GO:0005634; GO:0005654; GO:0005680; GO:0005737; GO:0005813; GO:0005819; GO:0007091; GO:0016567; GO:0019903; GO:0031145; GO:0051301; GO:0070936; GO:0070979; GO:0072686; GO:0141198
g20478	3330.923941	0.478432589	0.191232109	2.501842357	0.012354892	0.037019641	4356	2912	2400	3103	2781	3836	3883	2601	2910	3845	3762	3009	sp	Q5XGI3	FBXL5_XENTR	35.108	695	339	20	1	1854	1	660	1.26E-117	367	Q5XGI3	reviewed	FBXL5_XENTR	F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5)	fbxl5	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	660	GO:0005506; GO:0005634; GO:0006879; GO:0016567; GO:0019005; GO:0031146; GO:0048471; GO:0051536
g10811	1074.994566	2.095911211	0.415276791	5.047022265	4.49E-07	5.71E-06	916	906	976	742	2474	1764	711	370	335	473	437	380	sp	Q8VHQ2	SOCS7_MOUSE	59.88	167	66	1	2410	2907	386	552	3.15E-51	194	Q8VHQ2	reviewed	SOCS7_MOUSE	Suppressor of cytokine signaling 7 (SOCS-7)	Socs7 Cish7 Nap4	Mus musculus (Mouse)	579	GO:0005634; GO:0005737; GO:0005886; GO:0005942; GO:0008286; GO:0009968; GO:0016567; GO:0021799; GO:0021819; GO:0021942; GO:0031466; GO:0035556; GO:0043161; GO:0045444; GO:0046854; GO:0046935; GO:0140031; GO:1990756
g9089	101.7952018	-1.143933815	0.442646766	-2.584304017	0.009757574	0.030522999	73	83	87	66	29	9	195	152	136	229	209	94	sp	Q5ZM55	FEM1B_CHICK	49.44	625	289	2	64	1860	4	627	0	625	Q5ZM55	reviewed	FEM1B_CHICK	Protein fem-1 homolog B (FEM1b) (FEM1-beta)	FEM1B RCJMB04_3b14	Gallus gallus (Chicken)	627	GO:0005634; GO:0005737; GO:0006915; GO:0016567; GO:0031462; GO:0043161; GO:0140627; GO:1990756; GO:2000001
g20821	57.02825727	-2.815060645	0.715324679	-3.935360722	8.31E-05	0.000548999	14	30	35	0	0	16	174	183	83	136	75	79	sp	Q91ZT8	ASB9_MOUSE	37.594	266	154	7	52	837	30	287	3.29E-46	160	Q91ZT8	reviewed	ASB9_MOUSE	Ankyrin repeat and SOCS box protein 9 (ASB-9)	Asb9	Mus musculus (Mouse)	290	GO:0005739; GO:0016567; GO:0031466; GO:0035556; GO:0043161; GO:0045732; GO:1990756
g1707	334.5658188	-0.691274192	0.266099189	-2.59780646	0.009382136	0.029629423	186	179	222	309	164	238	903	554	348	490	443	339	sp	Q28DS3	RN170_XENTR	50.397	252	112	3	37	792	16	254	1.03E-76	236	Q28DS3	reviewed	RN170_XENTR	E3 ubiquitin-protein ligase RNF170 (EC 2.3.2.27) (RING finger protein 170) (RING-type E3 ubiquitin transferase RNF170)	rnf170 TGas116k14.1	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	257	GO:0005789; GO:0016567; GO:0046872; GO:0061630
g11700	8.775808123	1.984040349	0.685022075	2.896315931	0.003775721	0.014043631	11	19	18	5	7	14	7	4	4	10	0	2	sp	F1LZF0	KLHL2_RAT	31.683	101	59	4	4	285	218	315	5.79E-08	52.4	F1LZF0	reviewed	KLHL2_RAT	Kelch-like protein 2 (Mayven)	Klhl2	Rattus norvegicus (Rat)	593	GO:0001726; GO:0003779; GO:0005737; GO:0005829; GO:0015629; GO:0016567; GO:0030027; GO:0031463; GO:0042802; GO:1990756
g22030	631.6245495	2.527924341	0.457346473	5.527372549	3.25E-08	5.53E-07	1552	582	813	174	920	1285	353	174	174	276	233	172	sp	A0A0G2JZ79	SIR1_RAT	65.549	328	106	4	25	1005	1	322	4.33E-153	450	A0A0G2JZ79	reviewed	SIR1_RAT	NAD-dependent protein deacetylase sirtuin-1 (EC 2.3.1.286) (NAD-dependent protein deacylase sirtuin-1) (EC 2.3.1.-)	Sirt1	Rattus norvegicus (Rat)	555	GO:0000012; GO:0000122; GO:0000183; GO:0000720; GO:0000731; GO:0000785; GO:0000791; GO:0000792; GO:0000978; GO:0001525; GO:0001542; GO:0001678; GO:0001934; GO:0001938; GO:0002039; GO:0002821; GO:0003713; GO:0003714; GO:0004407; GO:0005634; GO:0005635; GO:0005637; GO:0005654; GO:0005677; GO:0005730; GO:0005737; GO:0005739; GO:0005829; GO:0006325; GO:0006642; GO:0006974; GO:0006979; GO:0007179; GO:0007283; GO:0007346; GO:0007517; GO:0007623; GO:0008284; GO:0008630; GO:0009267; GO:0010046; GO:0010460; GO:0010629; GO:0010659; GO:0010667; GO:0010824; GO:0010868; GO:0010875; GO:0010883; GO:0010906; GO:0010976; GO:0014858; GO:0016239; GO:0016567; GO:0016605; GO:0016922; GO:0017136; GO:0019213; GO:0019899; GO:0019904; GO:0030225; GO:0030424; GO:0030426; GO:0030512; GO:0031393; GO:0031507; GO:0031648; GO:0031667; GO:0032007; GO:0032041; GO:0032720; GO:0032868; GO:0032922; GO:0032991; GO:0033210; GO:0033553; GO:0033558; GO:0034391; GO:0034979; GO:0035098; GO:0035356; GO:0035358; GO:0035774; GO:0042127; GO:0042149; GO:0042220; GO:0042311; GO:0042393; GO:0042542; GO:0042595; GO:0042632; GO:0042771; GO:0042802; GO:0042981; GO:0043065; GO:0043066; GO:0043124; GO:0043161; GO:0043398; GO:0043422; GO:0043425; GO:0043518; GO:0043524; GO:0043536; GO:0044321; GO:0045348; GO:0045471; GO:0045599; GO:0045722; GO:0045739; GO:0045766; GO:0045786; GO:0045892; GO:0045944; GO:0046015; GO:0046628; GO:0046872; GO:0046969; GO:0046970; GO:0050872; GO:0051019; GO:0051152; GO:0051402; GO:0051658; GO:0051897; GO:0051898; GO:0055089; GO:0060125; GO:0060766; GO:0060907; GO:0061051; GO:0061773; GO:0070301; GO:0070403; GO:0070577; GO:0070857; GO:0070914; GO:0071236; GO:0071303; GO:0071356; GO:0071407; GO:0071456; GO:0071479; GO:0090312; GO:0090335; GO:0090400; GO:0097009; GO:0106230; GO:0106231; GO:0140297; GO:0140861; GO:0140937; GO:0141050; GO:0160012; GO:1900181; GO:1901797; GO:1901984; GO:1902166; GO:1902176; GO:1902237; GO:1902617; GO:1903427; GO:1904179; GO:1904373; GO:1904638; GO:1904639; GO:1904644; GO:1904646; GO:1904648; GO:1990254; GO:1990830; GO:1990841; GO:2000111; GO:2000270; GO:2000614; GO:2000655; GO:2000757; GO:2000773; GO:2000774; GO:2000781
g20337	126.8065414	-1.5478703	0.443012119	-3.493968297	0.000475898	0.00245149	87	71	50	114	12	19	334	270	158	261	206	174	sp	Q8WXK3	ASB13_HUMAN	46.332	259	139	0	43	819	20	278	2.57E-78	241	Q8WXK3	reviewed	ASB13_HUMAN	Ankyrin repeat and SOCS box protein 13 (ASB-13)	ASB13	Homo sapiens (Human)	278	GO:0005829; GO:0016567; GO:0035556
g21668	72.40486202	-0.987275905	0.368179946	-2.681503747	0.007329209	0.024199849	128	51	45	26	19	18	143	115	112	109	111	94	sp	Q5XGC0	FXL15_XENTR	41.538	260	152	0	46	825	8	267	1.66E-57	190	Q5XGC0	reviewed	FXL15_XENTR	F-box/LRR-repeat protein 15	fbxl15 TGas057g02.1	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	292	GO:0000086; GO:0005737; GO:0009953; GO:0016567; GO:0019005; GO:0030282; GO:0030513; GO:0031146
g21661	25.89632406	-2.084778723	0.860823169	-2.421843182	0.015442013	0.044242328	11	35	8	0	0	10	63	30	25	55	88	35	sp	Q5XH39	MARH8_XENLA	71.196	184	51	1	244	789	44	227	1.04E-95	285	Q5XH39	reviewed	MARH8_XENLA	E3 ubiquitin-protein ligase MARCHF8 (EC 2.3.2.27) (Membrane-associated RING finger protein 8) (Membrane-associated RING-CH protein VIII) (MARCH-VIII) (RING-type E3 ubiquitin transferase MARCHF8)	marchf8 march8	Xenopus laevis (African clawed frog)	264	GO:0002376; GO:0004842; GO:0005764; GO:0005765; GO:0005768; GO:0008270; GO:0016567; GO:0031901
g22417	262.6796218	-0.935224373	0.340551566	-2.74620488	0.00602891	0.020669522	188	178	177	193	63	134	879	746	205	343	231	288	sp	Q8BK06	FBX9_MOUSE	44.865	370	183	8	634	1719	81	437	3.70E-108	334	Q8BK06	reviewed	FBX9_MOUSE	F-box only protein 9	Fbxo9 MNCb-2471	Mus musculus (Mouse)	437	GO:0005737; GO:0016567; GO:0019005; GO:0031146; GO:0032006; GO:0045087; GO:0045444; GO:0070936; GO:1990756
g2819	64.96130194	-1.821135063	0.606126203	-3.004547655	0.002659761	0.010537708	17	39	74	3	18	12	195	129	35	119	148	115	sp	Q3TQF0	FBX31_MOUSE	36.977	430	222	10	49	1230	64	480	2.23E-81	262	Q3TQF0	reviewed	FBX31_MOUSE	F-box only protein 31	Fbxo31 MNCb-2609	Mus musculus (Mouse)	507	GO:0005813; GO:0006974; GO:0016567; GO:0019005; GO:0030332; GO:0031145; GO:0031146; GO:0031571; GO:0043025; GO:0050775; GO:2001224
g16388	194.4172314	-0.936531015	0.387746107	-2.415320229	0.015721381	0.044916001	148	50	110	81	163	85	367	336	209	361	327	237	sp	Q9R1R2	TRIM3_MOUSE	32.121	165	104	3	55	537	20	180	6.87E-19	91.3	Q9R1R2	reviewed	TRIM3_MOUSE	Tripartite motif-containing protein 3 (EC 2.3.2.27) (RING finger protein 22) (RING finger protein HAC1)	Trim3 Hac1 Rnf22	Mus musculus (Mouse)	744	GO:0000209; GO:0004842; GO:0005737; GO:0005769; GO:0005794; GO:0008270; GO:0015031; GO:0016567; GO:0017148; GO:0030371; GO:0030425; GO:0034141; GO:0042802; GO:0043161; GO:0061630; GO:0070534; GO:0098794; GO:0098978; GO:0140252
g17565	444.9472533	1.170451777	0.317323958	3.688507426	0.000225573	0.00129833	620	368	589	793	364	404	333	278	392	205	430	279	sp	Q6PFK1	ZN598_DANRE	56.506	269	114	2	28	834	55	320	2.87E-98	332	Q6PFK1	reviewed	ZN598_DANRE	E3 ubiquitin-protein ligase ZNF598 (EC 2.3.2.27) (Zinc finger protein 598)	znf598 zfp598	Danio rerio (Zebrafish) (Brachydanio rerio)	953	GO:0005829; GO:0006417; GO:0006513; GO:0016567; GO:0043022; GO:0046872; GO:0061630; GO:0070534; GO:0072344; GO:1990116
g17332	1123.45781	0.674777718	0.196103793	3.440921298	0.000579737	0.002904069	1243	949	1108	1138	1214	1101	1405	828	751	1068	1046	1158	sp	Q5SSH7	ZZEF1_MOUSE	36.364	825	424	16	4306	6672	2159	2918	3.34E-129	459	Q5SSH7	reviewed	ZZEF1_MOUSE	Zinc finger ZZ-type and EF-hand domain-containing protein 1	Zzef1 Kiaa0399	Mus musculus (Mouse)	2924	GO:0005509; GO:0007405; GO:0008270; GO:0008542; GO:0009986; GO:0016567; GO:0035064; GO:0035249; GO:0045202; GO:0048167; GO:0048786; GO:0050730; GO:0061659; GO:0070577; GO:0098794; GO:0140566
g4154	690.524714	-1.362381768	0.34675944	-3.928895976	8.53E-05	0.000561388	295	693	478	112	170	345	1950	1110	1494	1316	569	980	sp	O54928	SOCS5_MOUSE	60.326	184	70	1	1117	1668	346	526	2.33E-70	239	O54928	reviewed	SOCS5_MOUSE	Suppressor of cytokine signaling 5 (SOCS-5) (Cytokine-inducible SH2-containing protein 5)	Socs5 Cish5	Mus musculus (Mouse)	536	GO:0005154; GO:0005737; GO:0005942; GO:0007173; GO:0007175; GO:0007259; GO:0009968; GO:0016567; GO:0019210; GO:0019221; GO:0030971; GO:0032436; GO:0032715; GO:0035556; GO:0045627; GO:0045629; GO:0046854; GO:0046935; GO:0050728; GO:0071404; GO:0071638; GO:0097699; GO:1904988
g22031	354.2268636	2.609040438	0.440253394	5.92622447	3.10E-09	6.73E-08	982	371	380	142	582	540	160	116	147	108	82	116	sp	A0A0G2JZ79	SIR1_RAT	39.744	78	39	1	172	405	396	465	2.92E-07	54.3	A0A0G2JZ79	reviewed	SIR1_RAT	NAD-dependent protein deacetylase sirtuin-1 (EC 2.3.1.286) (NAD-dependent protein deacylase sirtuin-1) (EC 2.3.1.-)	Sirt1	Rattus norvegicus (Rat)	555	GO:0000012; GO:0000122; GO:0000183; GO:0000720; GO:0000731; GO:0000785; GO:0000791; GO:0000792; GO:0000978; GO:0001525; GO:0001542; GO:0001678; GO:0001934; GO:0001938; GO:0002039; GO:0002821; GO:0003713; GO:0003714; GO:0004407; GO:0005634; GO:0005635; GO:0005637; GO:0005654; GO:0005677; GO:0005730; GO:0005737; GO:0005739; GO:0005829; GO:0006325; GO:0006642; GO:0006974; GO:0006979; GO:0007179; GO:0007283; GO:0007346; GO:0007517; GO:0007623; GO:0008284; GO:0008630; GO:0009267; GO:0010046; GO:0010460; GO:0010629; GO:0010659; GO:0010667; GO:0010824; GO:0010868; GO:0010875; GO:0010883; GO:0010906; GO:0010976; GO:0014858; GO:0016239; GO:0016567; GO:0016605; GO:0016922; GO:0017136; GO:0019213; GO:0019899; GO:0019904; GO:0030225; GO:0030424; GO:0030426; GO:0030512; GO:0031393; GO:0031507; GO:0031648; GO:0031667; GO:0032007; GO:0032041; GO:0032720; GO:0032868; GO:0032922; GO:0032991; GO:0033210; GO:0033553; GO:0033558; GO:0034391; GO:0034979; GO:0035098; GO:0035356; GO:0035358; GO:0035774; GO:0042127; GO:0042149; GO:0042220; GO:0042311; GO:0042393; GO:0042542; GO:0042595; GO:0042632; GO:0042771; GO:0042802; GO:0042981; GO:0043065; GO:0043066; GO:0043124; GO:0043161; GO:0043398; GO:0043422; GO:0043425; GO:0043518; GO:0043524; GO:0043536; GO:0044321; GO:0045348; GO:0045471; GO:0045599; GO:0045722; GO:0045739; GO:0045766; GO:0045786; GO:0045892; GO:0045944; GO:0046015; GO:0046628; GO:0046872; GO:0046969; GO:0046970; GO:0050872; GO:0051019; GO:0051152; GO:0051402; GO:0051658; GO:0051897; GO:0051898; GO:0055089; GO:0060125; GO:0060766; GO:0060907; GO:0061051; GO:0061773; GO:0070301; GO:0070403; GO:0070577; GO:0070857; GO:0070914; GO:0071236; GO:0071303; GO:0071356; GO:0071407; GO:0071456; GO:0071479; GO:0090312; GO:0090335; GO:0090400; GO:0097009; GO:0106230; GO:0106231; GO:0140297; GO:0140861; GO:0140937; GO:0141050; GO:0160012; GO:1900181; GO:1901797; GO:1901984; GO:1902166; GO:1902176; GO:1902237; GO:1902617; GO:1903427; GO:1904179; GO:1904373; GO:1904638; GO:1904639; GO:1904644; GO:1904646; GO:1904648; GO:1990254; GO:1990830; GO:1990841; GO:2000111; GO:2000270; GO:2000614; GO:2000655; GO:2000757; GO:2000773; GO:2000774; GO:2000781
g21439	129.634645	-1.25343586	0.257227683	-4.872865344	1.10E-06	1.26E-05	91	92	101	56	28	50	265	257	151	184	258	204	sp	Q5M8S7	ZC3C1_XENTR	28.144	167	113	4	10	495	115	279	4.25E-12	70.1	Q5M8S7	reviewed	ZC3C1_XENTR	Zinc finger C3HC-type protein 1-like (NIPA-like protein)	zc3hc1 nipa	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	478	GO:0005635; GO:0008270; GO:0016567; GO:0051301
g5987	662.7451023	2.644714857	0.353194026	7.487994301	6.99E-14	3.65E-12	2078	1873	720	387	599	603	426	188	186	270	120	162	sp	A0JM49	LTN1_XENTR	37.358	795	438	18	265	2628	954	1695	2.86E-155	500	A0JM49	reviewed	LTN1_XENTR	E3 ubiquitin-protein ligase listerin (EC 2.3.2.27) (RING finger protein 160) (Zfp-294) (RING-type E3 ubiquitin transferase listerin)	ltn1 rnf160	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	1696	GO:0005829; GO:0008270; GO:0016567; GO:0061630; GO:1990112; GO:1990116
g703	536.0704618	0.849274835	0.274702885	3.091612365	0.001990726	0.00827448	678	607	506	548	599	454	508	398	406	754	258	470	sp	Q03601	NHL1_CAEEL	32.367	207	138	2	1897	2514	715	920	9.13E-37	127	Q03601	reviewed	NHL1_CAEEL	RING finger protein nhl-1	nhl-1 F54G8.4	Caenorhabditis elegans	974	GO:0000209; GO:0004842; GO:0016567; GO:0017148; GO:0030371; GO:0043161; GO:0046872; GO:0061630
g15513	63.05421072	-2.750592466	0.488811224	-5.62710578	1.83E-08	3.33E-07	33	20	18	15	1	8	155	109	86	117	218	102	sp	Q8VBV4	FBXW7_MOUSE	36.095	169	103	3	22	516	477	644	1.58E-25	105	Q8VBV4	reviewed	FBXW7_MOUSE	F-box/WD repeat-containing protein 7 (F-box and WD-40 domain-containing protein 7) (F-box protein FBW7) (F-box protein Fbxw6) (F-box-WD40 repeat protein 6) (SEL-10)	Fbxw7 Fbw7 Fbwd6 Fbxw6	Mus musculus (Mouse)	710	GO:0001570; GO:0005634; GO:0005694; GO:0005730; GO:0005737; GO:0005739; GO:0005783; GO:0005794; GO:0006281; GO:0006974; GO:0007062; GO:0007219; GO:0010629; GO:0010992; GO:0016020; GO:0016567; GO:0019005; GO:0030324; GO:0030332; GO:0030674; GO:0031146; GO:0031398; GO:0031625; GO:0031648; GO:0034644; GO:0042752; GO:0042802; GO:0043130; GO:0043161; GO:0045741; GO:0048471; GO:0048511; GO:0050816; GO:0050821; GO:0051443; GO:0070374; GO:0070534; GO:0090049; GO:0097027; GO:1901524; GO:1901800; GO:1903378; GO:1903955; GO:1990452; GO:1990756; GO:2000060; GO:2001205
g15512	57.64867688	-1.398105826	0.348392167	-4.013023129	5.99E-05	0.00041063	40	23	17	31	28	20	201	85	65	124	86	73	sp	D3Z902	FBXW7_RAT	40.449	89	52	1	259	522	357	445	2.72E-14	69.3	D3Z902	reviewed	FBXW7_RAT	F-box/WD repeat-containing protein 7	Fbxw7	Rattus norvegicus (Rat)	713	GO:0001570; GO:0005634; GO:0005694; GO:0005730; GO:0005737; GO:0005739; GO:0005783; GO:0005794; GO:0006281; GO:0006974; GO:0007062; GO:0007219; GO:0010629; GO:0010992; GO:0016567; GO:0019005; GO:0030324; GO:0030332; GO:0030674; GO:0031146; GO:0031398; GO:0031625; GO:0031648; GO:0042752; GO:0042802; GO:0043130; GO:0043161; GO:0048471; GO:0048511; GO:0050816; GO:0050821; GO:0070374; GO:0070534; GO:0090049; GO:0097027; GO:1901524; GO:1901800; GO:1903378; GO:1903955; GO:1990452; GO:1990756; GO:2000060; GO:2001205
g22264	686.1715999	1.003344755	0.389574251	2.575490428	0.010009804	0.031172514	948	1568	675	232	483	925	810	580	287	771	491	460	sp	A7E305	ZSWM8_BOVIN	66.942	242	69	2	562	1257	811	1051	4.44E-94	322	A7E305	reviewed	ZSWM8_BOVIN	Zinc finger SWIM domain-containing protein 8	ZSWIM8	Bos taurus (Bovine)	1413	GO:0005829; GO:0008270; GO:0016567; GO:0031462; GO:0031463; GO:0043161; GO:1990756; GO:2000627
g5908	76.1674891	-1.88776526	0.593306435	-3.181771086	0.001463775	0.006392026	75	37	54	17	0	26	362	79	87	162	134	94	sp	Q149N8	SHPRH_HUMAN	51.058	1040	481	13	2797	5868	649	1676	0	1038	Q149N8	reviewed	SHPRH_HUMAN	"E3 ubiquitin-protein ligase SHPRH (EC 2.3.2.27) (EC 3.6.4.-) (RING-type E3 ubiquitin transferase SHPRH) (SNF2, histone-linker, PHD and RING finger domain-containing helicase)"	SHPRH KIAA2023	Homo sapiens (Human)	1683	GO:0000209; GO:0000786; GO:0003677; GO:0004386; GO:0004842; GO:0005524; GO:0005654; GO:0006281; GO:0006334; GO:0006974; GO:0016567; GO:0016787; GO:0031625; GO:0046872; GO:0061630; GO:0140658
g6596	747.1687304	1.047556137	0.26990058	3.88126671	0.000103914	0.00066633	934	640	609	731	1024	896	776	576	383	669	566	497	sp	Q8CF97	VCIP1_RAT	44.811	1031	455	18	19	3045	36	974	0	862	Q8CF97	reviewed	VCIP1_RAT	Deubiquitinating protein VCPIP1 (EC 3.4.19.12) (Valosin-containing protein p97/p47 complex-interacting protein 1) (Valosin-containing protein p97/p47 complex-interacting protein p135) (VCP/p47 complex-interacting 135-kDa protein)	Vcpip1 Vcip135	Rattus norvegicus (Rat)	1221	GO:0004843; GO:0005634; GO:0005783; GO:0005795; GO:0006508; GO:0006974; GO:0007030; GO:0016320; GO:0016567; GO:0016579; GO:0035871; GO:0045202; GO:0071108; GO:0090168; GO:0106300; GO:1905634
g9101	488.9009688	1.514023195	0.293845791	5.15244132	2.57E-07	3.50E-06	701	604	484	475	687	566	447	278	268	334	162	361	sp	Q9Y4L5	RN115_HUMAN	36.455	299	160	7	52	939	19	290	3.27E-53	179	Q9Y4L5	reviewed	RN115_HUMAN	E3 ubiquitin-protein ligase RNF115 (EC 2.3.2.27) (RING finger protein 115) (RING-type E3 ubiquitin transferase RNF115) (Rab7-interacting RING finger protein) (Rabring 7) (Zinc finger protein 364)	RNF115 ZNF364	Homo sapiens (Human)	304	GO:0004842; GO:0005634; GO:0005737; GO:0005783; GO:0005794; GO:0005829; GO:0016567; GO:0034122; GO:0042059; GO:0043162; GO:0046872; GO:0051865; GO:0061630; GO:0070534; GO:0070936; GO:0070979
g15896	410.5635131	2.312996332	0.530354365	4.361228045	1.29E-05	0.000110831	704	78	252	423	759	957	152	93	140	82	215	173	sp	Q9UPN9	TRI33_HUMAN	26.923	338	210	12	49	999	122	443	1.93E-20	101	Q9UPN9	reviewed	TRI33_HUMAN	E3 ubiquitin-protein ligase TRIM33 (EC 2.3.2.27) (Ectodermin homolog) (RET-fused gene 7 protein) (Protein Rfg7) (RING-type E3 ubiquitin transferase TRIM33) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33)	TRIM33 KIAA1113 RFG7 TIF1G	Homo sapiens (Human)	1127	GO:0000122; GO:0000785; GO:0003677; GO:0004842; GO:0005634; GO:0005654; GO:0008270; GO:0016567; GO:0017015; GO:0030514; GO:0045892; GO:0070410; GO:0070412
g15898	598.2029986	2.872144717	0.570085542	5.038094294	4.70E-07	5.96E-06	1373	149	431	549	1381	909	252	173	174	97	84	202	sp	Q9UPN9	TRI33_HUMAN	26.923	338	210	12	49	999	122	443	1.93E-20	101	Q9UPN9	reviewed	TRI33_HUMAN	E3 ubiquitin-protein ligase TRIM33 (EC 2.3.2.27) (Ectodermin homolog) (RET-fused gene 7 protein) (Protein Rfg7) (RING-type E3 ubiquitin transferase TRIM33) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33)	TRIM33 KIAA1113 RFG7 TIF1G	Homo sapiens (Human)	1127	GO:0000122; GO:0000785; GO:0003677; GO:0004842; GO:0005634; GO:0005654; GO:0008270; GO:0016567; GO:0017015; GO:0030514; GO:0045892; GO:0070410; GO:0070412
g11191	101.7078564	-1.627412519	0.216937822	-7.501746364	6.30E-14	3.32E-12	71	65	59	33	26	18	343	201	186	164	114	148	sp	A6H7H7	FBX3_BOVIN	33.565	432	253	12	1	1260	4	413	6.25E-55	192	A6H7H7	reviewed	FBX3_BOVIN	F-box only protein 3	FBXO3 FBX3	Bos taurus (Bovine)	469	GO:0005634; GO:0005737; GO:0016567; GO:0019005; GO:0031146; GO:0032496; GO:1990756
g1579	374.0886846	-1.288986854	0.294826991	-4.372011021	1.23E-05	0.000106307	248	260	258	259	53	116	835	701	512	609	727	482	sp	Q5T447	HECD3_HUMAN	53.371	875	387	10	1	2613	1	858	0	922	Q5T447	reviewed	HECD3_HUMAN	E3 ubiquitin-protein ligase HECTD3 (EC 2.3.2.26) (HECT domain-containing protein 3) (HECT-type E3 ubiquitin transferase HECTD3)	HECTD3	Homo sapiens (Human)	861	GO:0004842; GO:0016567; GO:0019905; GO:0043161; GO:0048471
g8551	27251.66345	1.547404394	0.276016286	5.606206844	2.07E-08	3.70E-07	39530	23207	27849	26574	33503	48158	23216	16855	12948	21725	11854	13268	sp	P62976	UBIQP_CRIGR	99.476	382	2	0	1	1146	1	382	0	752	P62976	reviewed	UBIQP_CRIGR	Polyubiquitin [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]		Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)	658	GO:0005634; GO:0005737; GO:0016567; GO:0019941; GO:0031386; GO:0031625
g8552	24859.66288	1.490299938	0.273392897	5.451128951	5.01E-08	8.14E-07	33056	23775	25783	22984	32402	40238	23181	17067	12201	16716	11681	13257	sp	P0CG50	UBC_MOUSE	98.653	297	2	1	1	885	1	297	0	580	P0CG50	reviewed	UBC_MOUSE	Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]	Ubc	Mus musculus (Mouse)	734	GO:0002020; GO:0005654; GO:0005741; GO:0005829; GO:0016567; GO:0019941; GO:0031386; GO:0031625; GO:0043209
g12095	68.97970729	-1.509372507	0.620649869	-2.431922702	0.015018912	0.043317704	41	58	64	24	0	30	141	53	152	163	65	157	sp	Q3TUL7	DCA17_MOUSE	28.545	536	328	17	19	1566	4	504	2.90E-52	189	Q3TUL7	reviewed	DCA17_MOUSE	DDB1- and CUL4-associated factor 17	Dcaf17	Mus musculus (Mouse)	519	GO:0005654; GO:0005730; GO:0005829; GO:0016020; GO:0016567; GO:0080008
g2565	2891.159556	1.673522747	0.308535094	5.42409203	5.82E-08	9.37E-07	4607	3480	2293	2553	4383	3822	2725	1296	832	2108	1625	1596	sp	Q924T7	RNF31_MOUSE	37.829	608	338	14	931	2715	432	1012	2.84E-110	367	Q924T7	reviewed	RNF31_MOUSE	E3 ubiquitin-protein ligase RNF31 (EC 2.3.2.31) (HOIL-1-interacting protein) (HOIP) (Putative Ariadne-like ubiquitin ligase) (PAUL) (RING finger protein 31) (RING-type E3 ubiquitin transferase RNF31)	Rnf31 Paul	Mus musculus (Mouse)	1066	GO:0000209; GO:0004842; GO:0005829; GO:0008270; GO:0009898; GO:0016567; GO:0023035; GO:0031625; GO:0033209; GO:0035631; GO:0036435; GO:0042742; GO:0042802; GO:0043123; GO:0043130; GO:0050852; GO:0051092; GO:0060546; GO:0061630; GO:0070530; GO:0071797; GO:0097039; GO:1904417; GO:1990450
g18093	128.3940596	0.994743507	0.396320807	2.509945199	0.01207499	0.03637035	171	202	95	70	107	221	229	51	60	117	84	118	sp	Q8TEJ3	SH3R3_HUMAN	34.94	581	186	19	1	1485	46	520	4.04E-74	267	Q8TEJ3	reviewed	SH3R3_HUMAN	E3 ubiquitin-protein ligase SH3RF3 (EC 2.3.2.27) (Plenty of SH3s 2) (SH3 domain-containing RING finger protein 3) (SH3 multiple domains protein 4)	SH3RF3 POSH2 SH3MD4	Homo sapiens (Human)	882	GO:0016567; GO:0032436; GO:0046330; GO:0046872; GO:0051865; GO:0061630
g21912	16.21312829	2.12501202	0.840181037	2.529231116	0.011431273	0.034766207	36	6	24	11	33	8	19	13	15	2	0	6	sp	P0CE12	SSPH2_SALTY	34.392	189	122	2	675	112	234	421	1.41E-09	61.2	P0CE12	reviewed	SSPH2_SALTY	E3 ubiquitin-protein ligase SspH2 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase SspH2) (Salmonella secreted protein H2) (Secreted effector protein sspH2)	sspH2 STM2241	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	788	GO:0003824; GO:0004842; GO:0005576; GO:0016020; GO:0016567; GO:0020002; GO:0030254; GO:0030430; GO:0032757; GO:0034052; GO:0061630; GO:0070430
g388	129.0018382	-1.881812285	0.31359682	-6.00073778	1.96E-09	4.48E-08	46	69	61	74	13	33	416	202	217	290	164	238	sp	O70277	TRIM3_RAT	20.455	176	138	1	109	636	115	288	6.23E-07	55.8	O70277	reviewed	TRIM3_RAT	Tripartite motif-containing protein 3 (EC 2.3.2.27) (Brain-expressed RING finger protein) (RING finger protein 22)	Trim3 Berp Rnf22	Rattus norvegicus (Rat)	744	GO:0000209; GO:0004842; GO:0005737; GO:0005769; GO:0005794; GO:0008270; GO:0015031; GO:0016567; GO:0017148; GO:0030371; GO:0030425; GO:0034141; GO:0042802; GO:0043161; GO:0061630; GO:0070534; GO:0098794; GO:0098978; GO:0140252
g17153	278.3101639	-0.599812117	0.234784107	-2.554739011	0.010626744	0.032722593	254	138	250	182	131	181	571	333	339	448	502	268	sp	Q9UPQ7	PZRN3_HUMAN	35.849	212	126	7	1	612	1	210	5.71E-30	129	Q9UPQ7	reviewed	PZRN3_HUMAN	E3 ubiquitin-protein ligase PDZRN3 (EC 2.3.2.27) (Ligand of Numb protein X 3) (PDZ domain-containing RING finger protein 3) (RING-type E3 ubiquitin transferase PDZRN3) (Semaphorin cytoplasmic domain-associated protein 3) (Protein SEMACAP3)	PDZRN3 KIAA1095 LNX3 SEMCAP3	Homo sapiens (Human)	1066	GO:0004842; GO:0005737; GO:0007528; GO:0008270; GO:0016567; GO:0031594; GO:0061630
g6658	254.2832807	-0.786828692	0.233706018	-3.366745539	0.000760608	0.00364813	144	186	156	235	82	164	594	344	409	327	364	326	sp	P61963	DCAF7_MOUSE	90.029	341	34	0	7	1029	2	342	0	659	P61963	reviewed	DCAF7_MOUSE	DDB1- and CUL4-associated factor 7 (WD repeat-containing protein 68) (WD repeat-containing protein An11 homolog)	Dcaf7 Han11 Wdr68	Mus musculus (Mouse)	342	GO:0005634; GO:0005829; GO:0016363; GO:0016567; GO:0016604; GO:0032991; GO:0080008
g9682	102.8374308	-2.587853585	0.411434661	-6.289828817	3.18E-10	8.55E-09	32	23	59	25	12	11	398	214	93	296	209	131	sp	Q9W3M3	UBR3_DROME	42.619	420	235	4	25	1281	155	569	4.49E-102	337	Q9W3M3	reviewed	UBR3_DROME	E3 ubiquitin-protein ligase Ubr3 (EC 2.3.2.27) (E3 ubiquitin-protein transferase Ubr3)	Ubr3 CG42593	Drosophila melanogaster (Fruit fly)	2219	GO:0000151; GO:0005634; GO:0005737; GO:0005829; GO:0007605; GO:0008270; GO:0016567; GO:0043025; GO:0043066; GO:0045880; GO:0051865; GO:0061630; GO:0070936; GO:0071596
g20353	49.41645355	2.677833168	0.91656034	2.921611434	0.003482257	0.013133213	39	195	100	16	6	119	15	19	0	4	36	22	sp	Q3V0Q1	DYH12_MOUSE	71.377	276	79	0	79	906	2811	3086	4.33E-135	426	Q3V0Q1	reviewed	DYH12_MOUSE	Dynein axonemal heavy chain 12 (Axonemal beta dynein heavy chain 12) (Axonemal dynein heavy chain 12-like protein) (Axonemal dynein heavy chain 7-like protein) (Ciliary dynein heavy chain 12)	Dnah12 Dnah12l Dnah7l Dnahc12 Dnahc7l	Mus musculus (Mouse)	3086	GO:0005524; GO:0005874; GO:0008569; GO:0016567; GO:0016887; GO:0036156; GO:0045505; GO:0051959; GO:0060294; GO:0097729
g12803	1373.874696	2.653761591	0.892325083	2.9739852	0.002939593	0.011436386	406	4842	2034	364	2834	366	579	180	14	1552	997	155	sp	Q5REG4	DTX3_PONAB	50.526	190	93	1	2233	2799	155	344	2.62E-55	198	Q5REG4	reviewed	DTX3_PONAB	Probable E3 ubiquitin-protein ligase DTX3 (EC 2.3.2.27) (Protein deltex-3) (Deltex3) (RING-type E3 ubiquitin transferase DTX3)	DTX3	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	347	GO:0005654; GO:0005737; GO:0007219; GO:0016567; GO:0046872; GO:0061630
g15347	154.1745556	-0.700926704	0.292723472	-2.394501192	0.016642989	0.047050652	78	113	123	161	42	97	284	233	234	222	256	153	sp	Q9QZN1	FXL17_MOUSE	35.194	412	258	5	541	1758	284	692	3.53E-71	245	Q9QZN1	reviewed	FXL17_MOUSE	F-box/LRR-repeat protein 17 (F-box and leucine-rich repeat protein 17) (F-box only protein 13)	Fbxl17 Fbl17 Fbx13 Fbxo13	Mus musculus (Mouse)	701	GO:0000209; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006515; GO:0007399; GO:0008589; GO:0014033; GO:0016567; GO:0019005; GO:0031146; GO:0043153; GO:0043161
g6071	283.7855776	-0.975529927	0.283602979	-3.439773196	0.000582202	0.002913879	171	174	244	237	99	72	598	476	334	460	438	449	sp	Q8N5D0	WDTC1_HUMAN	51.403	677	297	11	16	2034	4	652	0	661	Q8N5D0	reviewed	WDTC1_HUMAN	WD and tetratricopeptide repeats protein 1	WDTC1 KIAA1037	Homo sapiens (Human)	677	GO:0000122; GO:0001701; GO:0004857; GO:0005654; GO:0005737; GO:0005829; GO:0006006; GO:0008361; GO:0016567; GO:0032869; GO:0035264; GO:0042393; GO:0042826; GO:0045717; GO:0055082; GO:0080008
g4300	5142.349823	4.966493369	1.175953167	4.22337684	2.41E-05	0.000190483	509	4385	32776	39	108	17559	13	228	674	97	457	577	sp	P80146	SEPR_THESR	39.633	381	202	9	52	1119	30	407	5.67E-75	241	P80146	reviewed	SEPR_THESR	Extracellular serine proteinase (EC 3.4.21.-)		Thermus sp. (strain Rt41A)	410	GO:0004252; GO:0005615; GO:0006508
g4302	43.20475841	-1.577818592	0.579285114	-2.723734052	0.006454846	0.021822083	37	44	15	4	7	17	103	76	18	147	63	74	sp	P10394	POL4_DROME	25.872	344	226	4	157	1143	882	1211	5.33E-36	145	P10394	reviewed	POL4_DROME	Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	POL ORF3	Drosophila melanogaster (Fruit fly)	1237	GO:0003676; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575
g15976	2356.405637	1.022570672	0.271293494	3.769241413	0.000163744	0.000986238	3299	2106	1812	3291	2703	2322	2400	1582	2115	1814	1612	1524	sp	Q92542	NICA_HUMAN	36.061	721	368	22	25	2007	14	701	5.74E-132	408	Q92542	reviewed	NICA_HUMAN	Nicastrin	NCSTN KIAA0253 UNQ1874/PRO4317	Homo sapiens (Human)	709	GO:0000139; GO:0002262; GO:0005765; GO:0005769; GO:0005783; GO:0005789; GO:0005794; GO:0005886; GO:0005925; GO:0006508; GO:0006509; GO:0007212; GO:0007215; GO:0007219; GO:0007220; GO:0007611; GO:0008021; GO:0010008; GO:0010950; GO:0016020; GO:0016485; GO:0021549; GO:0022010; GO:0030534; GO:0030674; GO:0031293; GO:0034205; GO:0035577; GO:0042098; GO:0042383; GO:0042470; GO:0042500; GO:0042734; GO:0042982; GO:0042983; GO:0042986; GO:0042987; GO:0050673; GO:0051117; GO:0051402; GO:0070062; GO:0070765; GO:0070851; GO:0071277; GO:1900271; GO:1990926
g19177	8263.458769	4.490716627	1.141767417	3.933127325	8.38E-05	0.000553069	601	7678	34428	102	274	40983	57	476	1915	190	1063	901	sp	P48052	CBPA2_HUMAN	37.688	398	232	6	70	1242	22	410	6.70E-92	286	P48052	reviewed	CBPA2_HUMAN	Carboxypeptidase A2 (EC 3.4.17.15)	CPA2	Homo sapiens (Human)	419	GO:0004180; GO:0004181; GO:0005576; GO:0005615; GO:0005773; GO:0006508; GO:0007039; GO:0008270
g5599	182.4162259	1.780839632	0.668263945	2.66487463	0.007701703	0.025217526	190	441	330	39	240	186	181	200	7	56	112	65	sp	Q8N7X0	ADGB_HUMAN	34.393	535	254	7	2263	3849	629	1072	8.13E-89	321	Q8N7X0	reviewed	ADGB_HUMAN	Androglobin	ADGB C6orf103	Homo sapiens (Human)	1667	GO:0004198; GO:0006508; GO:0007286; GO:0019825; GO:0020037; GO:0046872; GO:0097225; GO:0097227
g5598	125.3411437	1.861566578	0.624265129	2.982012754	0.002863601	0.011196257	109	361	292	10	88	201	104	104	24	47	76	38	sp	G3UZ78	ADGB_MOUSE	39.322	295	151	6	1	807	1120	1412	4.61E-35	143	G3UZ78	reviewed	ADGB_MOUSE	Androglobin	Adgb	Mus musculus (Mouse)	1657	GO:0004198; GO:0006508; GO:0007283; GO:0007286; GO:0019825; GO:0020037; GO:0036126; GO:0046872; GO:0097225; GO:0097227
g22207	247.1743812	-0.76219347	0.29749093	-2.56207297	0.010404945	0.032205517	201	138	226	244	83	73	437	401	329	465	280	360	sp	Q5ZIM5	MAP1_CHICK	69.231	364	102	3	16	1077	3	366	0	543	Q5ZIM5	reviewed	MAP1_CHICK	Methionine aminopeptidase 1 (MAP 1) (MetAP 1) (EC 3.4.11.18) (Peptidase M 1)	METAP1 RCJMB04_24o19	Gallus gallus (Chicken)	385	GO:0004239; GO:0005829; GO:0006508; GO:0022626; GO:0046872; GO:0070006
g2736	4857.685739	-1.005243743	0.288862673	-3.480005678	0.000501403	0.002567553	2738	3493	4338	2702	1292	2562	9741	10021	7300	4272	10045	5334	sp	Q5I0D7	PEPD_RAT	62.947	475	175	1	10	1434	7	480	0	577	Q5I0D7	reviewed	PEPD_RAT	Xaa-Pro dipeptidase (X-Pro dipeptidase) (EC 3.4.13.9) (Imidodipeptidase) (Peptidase D) (Proline dipeptidase) (Prolidase)	Pepd	Rattus norvegicus (Rat)	492	GO:0006508; GO:0008233; GO:0030145; GO:0030574; GO:0043069; GO:0070006; GO:0102009
g13145	125.6000211	-2.862969727	0.481523708	-5.945646458	2.75E-09	6.03E-08	21	53	8	21	30	14	307	246	170	287	420	162	sp	P08594	AQL1_THEAQ	45.932	381	176	9	73	1188	37	396	1.44E-78	254	P08594	reviewed	AQL1_THEAQ	Aqualysin-1 (EC 3.4.21.111) (Aqualysin-I)	pstI	Thermus aquaticus	513	GO:0004252; GO:0005615; GO:0006508
g11371	416.4978125	3.158108398	0.701617543	4.5011822	6.76E-06	6.30E-05	1494	572	854	719	288	203	190	48	33	42	11	310	sp	Q9QX15	CA3A1_MOUSE	31.737	668	396	20	1	1941	238	866	1.02E-75	267	Q9QX15	reviewed	CA3A1_MOUSE	Calcium-activated chloride channel regulator 3A-1 (EC 3.4.-.-)	Clca3a1 Clca1	Mus musculus (Mouse)	902	GO:0005229; GO:0005886; GO:0006508; GO:0006821; GO:0008237; GO:0046872
g11370	81.00515206	3.235856603	0.775930684	4.170290815	3.04E-05	0.000233702	287	86	234	121	55	36	55	4	14	9	0	37	sp	Q9D7Z6	CLCA1_MOUSE	38.095	126	78	0	88	465	21	146	3.04E-34	107	Q9D7Z6	reviewed	CLCA1_MOUSE	Calcium-activated chloride channel regulator 1 (EC 3.4.-.-) (Calcium-activated chloride channel family member 3) (mCLCA3) (Protein gob-5)	Clca1 Clca3 Gob5	Mus musculus (Mouse)	913	GO:0005229; GO:0005254; GO:0005576; GO:0005886; GO:0005902; GO:0006508; GO:0006816; GO:0006821; GO:0008237; GO:0016020; GO:0030141; GO:0042589; GO:0046872; GO:0071456
g21051	182.1531723	-2.0710834	0.389940124	-5.311285693	1.09E-07	1.63E-06	51	97	78	83	12	57	427	402	225	594	195	341	sp	Q96LD8	SENP8_HUMAN	50.962	208	99	3	25	642	5	211	2.12E-62	196	Q96LD8	reviewed	SENP8_HUMAN	"Sentrin-specific protease 8 (EC 3.4.22.-) (Deneddylase-1) (NEDD8-specific protease 1) (Protease, cysteine 2) (Sentrin/SUMO-specific protease SENP8)"	SENP8 DEN1 NEDP1 PRSC2 FKSG8	Homo sapiens (Human)	212	GO:0000338; GO:0005829; GO:0006508; GO:0008234; GO:0016579; GO:0019784; GO:0043687
g21697	21983.83252	-0.582456648	0.240024365	-2.426656342	0.015238683	0.043827977	14426	15160	13709	22973	11431	11519	40630	35183	32808	31321	27124	23940	sp	P79729	DHH_DANRE	47.191	89	38	2	976	1239	7	87	1.70E-15	75.9	P79729	reviewed	DHH_DANRE	Desert hedgehog protein (DHH)	dhh	Danio rerio (Zebrafish) (Brachydanio rerio)	88	GO:0005576; GO:0005886; GO:0006508; GO:0007267; GO:0008233; GO:0046872
g8939	34.55383979	-1.663912101	0.607120755	-2.740660878	0.006131576	0.020934189	12	20	32	7	0	20	68	46	30	102	68	72	sp	P0C872	JMJD7_MOUSE	54.967	302	126	1	58	963	20	311	2.73E-129	374	P0C872	reviewed	JMJD7_MOUSE	Bifunctional peptidase and (3S)-lysyl hydroxylase Jmjd7 (EC 1.14.11.63) (EC 3.4.-.-) (JmjC domain-containing protein 7) (Jumonji domain-containing protein 7) (L-lysine (3S)-hydroxylase Jmjd7)	Jmjd7	Mus musculus (Mouse)	316	GO:0004175; GO:0004177; GO:0004497; GO:0005634; GO:0005737; GO:0006508; GO:0016706; GO:0035064; GO:0046872; GO:0106155
g1986	267.7273344	0.973592473	0.32696147	2.97769787	0.002904221	0.011331977	384	225	237	310	318	253	427	253	200	217	134	138	sp	Q96DT6	ATG4C_HUMAN	41.791	268	95	5	886	1521	11	273	2.48E-62	221	Q96DT6	reviewed	ATG4C_HUMAN	Cysteine protease ATG4C (EC 3.4.22.-) (AUT-like 3 cysteine endopeptidase) (Autophagy-related cysteine endopeptidase 3) (Autophagin-3) (Autophagy-related protein 4 homolog C) (HsAPG4C)	ATG4C APG4C AUTL1 AUTL3	Homo sapiens (Human)	458	GO:0000045; GO:0000423; GO:0004197; GO:0005737; GO:0006508; GO:0006914; GO:0008234; GO:0015031; GO:0016485; GO:0019786; GO:0034727; GO:0035973; GO:0051697
g19215	58.17206441	-2.48360354	0.819685247	-3.029947836	0.00244596	0.009832827	64	69	25	10	0	0	116	110	92	117	118	89	sp	A2BGT0	UBP30_DANRE	32.576	264	136	9	88	813	46	289	8.29E-30	122	A2BGT0	reviewed	UBP30_DANRE	Ubiquitin carboxyl-terminal hydrolase 30 (EC 3.4.19.12) (Deubiquitinating enzyme 30) (Ubiquitin thioesterase 30) (Ubiquitin-specific-processing protease 30) (Ub-specific protease 30)	usp30 si:dkey-72n1.2	Danio rerio (Zebrafish) (Brachydanio rerio)	491	GO:0000422; GO:0004197; GO:0004843; GO:0005634; GO:0005739; GO:0005741; GO:0005829; GO:0006508; GO:0008053; GO:0016579; GO:0035871; GO:0044313
g17554	641.4833464	1.273963787	0.311020967	4.096070431	4.20E-05	0.000304715	1485	1339	709	375	294	833	558	425	385	379	482	441	sp	Q6ICB0	DESI1_HUMAN	56.604	159	69	0	19	495	9	167	8.69E-57	190	Q6ICB0	reviewed	DESI1_HUMAN	Desumoylating isopeptidase 1 (DeSI-1) (EC 3.4.-.-) (PPPDE peptidase domain-containing protein 2) (Palmitoyl protein thioesterase DESI1) (EC 3.1.2.22) (Polyubiquitinated substrate transporter) (POST) (S-depalmitoylase DESI1)	DESI1 FAM152B PPPDE2	Homo sapiens (Human)	168	GO:0005634; GO:0005829; GO:0006508; GO:0006611; GO:0008474; GO:0016926; GO:0016929; GO:0032434; GO:0032991; GO:0042802; GO:0052816; GO:0061676; GO:0070646
g12071	40.96691052	3.750862276	1.254665525	2.989531632	0.002794055	0.010981553	12	94	126	16	0	164	0	5	19	7	8	0	sp	P29787	TRY5_AEDAE	40.329	243	125	8	61	777	34	260	7.77E-49	165	P29787	reviewed	TRY5_AEDAE	Trypsin 5G1 (EC 3.4.21.4)	AAEL013712	Aedes aegypti (Yellowfever mosquito) (Culex aegypti)	266	GO:0004252; GO:0005615; GO:0006508; GO:0007586
g19004	607.3505702	3.766196088	0.716300068	5.257846892	1.46E-07	2.11E-06	1716	333	983	121	662	1858	132	83	346	20	55	63	sp	Q9Y5R2	MMP24_HUMAN	39.602	553	285	15	229	1785	80	617	1.67E-108	343	Q9Y5R2	reviewed	MMP24_HUMAN	Matrix metalloproteinase-24 (MMP-24) (EC 3.4.24.-) (Membrane-type matrix metalloproteinase 5) (MT-MMP 5) (MTMMP5) (Membrane-type-5 matrix metalloproteinase) (MT5-MMP) (MT5MMP) [Cleaved into: Processed matrix metalloproteinase-24]	MMP24 MT5MMP	Homo sapiens (Human)	645	GO:0004222; GO:0005615; GO:0005886; GO:0006508; GO:0008047; GO:0008270; GO:0010001; GO:0030198; GO:0030574; GO:0031012; GO:0032588; GO:0044331; GO:0045296; GO:0050965; GO:0070062; GO:0097150; GO:0098742
g16586	139.9637383	3.49792319	0.860727673	4.063913941	4.83E-05	0.00034266	189	996	92	34	18	189	54	24	16	44	0	13	sp	P58873	RHBL3_MOUSE	38.095	147	87	2	190	630	31	173	1.15E-22	97.8	P58873	reviewed	RHBL3_MOUSE	Rhomboid-related protein 3 (EC 3.4.21.105) (Ventrhoid transmembrane protein)	Rhbdl3 Rhbdl4 Vrho	Mus musculus (Mouse)	404	GO:0004252; GO:0005509; GO:0006508; GO:0016020
g18353	254.6534988	-1.12040042	0.26380492	-4.247079314	2.17E-05	0.00017324	117	150	237	168	61	109	447	410	310	444	464	446	sp	O02467	ASPG_SPOFR	58.805	318	129	2	67	1017	4	320	6.77E-108	321	O02467	reviewed	ASPG_SPOFR	N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase (EC 3.5.1.26) (Aspartylglucosaminidase) (AGA) (Glycosylasparaginase) (N4-(N-acetyl-beta-glucosaminyl)-L-asparagine amidase) [Cleaved into: Glycosylasparaginase alpha chain; Glycosylasparaginase beta chain]		Spodoptera frugiperda (Fall armyworm)	320	GO:0003948; GO:0004067; GO:0005764; GO:0006508; GO:0008798
g21154	1474.734777	2.293253746	0.356679358	6.429454622	1.28E-10	3.78E-09	2618	1106	1712	1508	2601	2089	798	370	707	491	597	536	sp	A6QR55	UBP4_BOVIN	67.982	228	70	1	1	675	1	228	5.19E-103	330	A6QR55	reviewed	UBP4_BOVIN	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.4.19.12) (Deubiquitinating enzyme 4) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4)	USP4	Bos taurus (Bovine)	963	GO:0000244; GO:0004843; GO:0005634; GO:0005737; GO:0006508; GO:0016579; GO:0031397; GO:0031647; GO:0034394; GO:0046872; GO:1904263
g21155	1542.828729	2.340982311	0.366839555	6.381488251	1.75E-10	4.98E-09	2805	1163	1756	1495	2763	2235	831	513	698	440	455	645	sp	B2GUZ1	UBP4_RAT	46.121	464	227	7	1	1332	489	949	1.16E-121	381	B2GUZ1	reviewed	UBP4_RAT	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.4.19.12) (Deubiquitinating enzyme 4) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4)	Usp4	Rattus norvegicus (Rat)	961	GO:0000244; GO:0004843; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0006508; GO:0016579; GO:0031397; GO:0031647; GO:0031685; GO:0034394; GO:0042802; GO:0046872; GO:1904263
g5810	176.4861681	-1.376621638	0.290801223	-4.733892187	2.20E-06	2.35E-05	77	140	73	97	61	54	410	360	168	367	321	250	sp	Q9CXT6	KDM8_MOUSE	28.696	230	146	8	148	795	189	414	1.34E-18	90.9	Q9CXT6	reviewed	KDM8_MOUSE	Bifunctional peptidase and arginyl-hydroxylase JMJD5 (EC 1.14.11.73) (EC 3.4.-.-) (JmjC domain-containing protein 5) (Jumonji C domain-containing protein 5) (L-arginine (3R)-hydroxylase KDM8) (Lysine-specific demethylase 8)	Kdm8 Jmjd5	Mus musculus (Mouse)	414	GO:0000086; GO:0001701; GO:0002039; GO:0003682; GO:0004175; GO:0004177; GO:0005634; GO:0005654; GO:0005694; GO:0005829; GO:0006508; GO:0031648; GO:0032922; GO:0035064; GO:0045892; GO:0045893; GO:0046872; GO:0048144; GO:0051864; GO:0106157; GO:1901796
g1332	96.71472845	-1.084765295	0.40839638	-2.656157956	0.007903658	0.025751784	93	115	62	61	8	26	185	143	130	172	174	135	sp	P47245	NRDC_RAT	45.028	362	184	8	1	1074	809	1159	1.16E-90	298	P47245	reviewed	NRDC_RAT	Nardilysin (EC 3.4.24.61) (N-arginine dibasic convertase) (NRD convertase) (NRD-C) (Nardilysin convertase)	Nrdc Nrd1	Rattus norvegicus (Rat)	1161	GO:0004222; GO:0005739; GO:0006508; GO:0008233; GO:0030425; GO:0031643; GO:0046872; GO:0050772; GO:0051044; GO:0120163
g23743	2254.463507	1.361279172	0.261608051	5.203506409	1.96E-07	2.74E-06	2549	1912	1911	4182	2804	2474	1483	1415	1408	1559	1345	1383	sp	P55866	CASP3_XENLA	38.764	178	89	5	538	1068	122	280	2.35E-27	112	P55866	reviewed	CASP3_XENLA	Caspase-3 (CASP-3) (EC 3.4.22.56) (Apopain) (Cysteine protease CPP32) (xCPP32) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12]	casp3	Xenopus laevis (African clawed frog)	282	GO:0004175; GO:0005737; GO:0006508; GO:0097200
g9438	6985.562582	2.218480959	0.336981388	6.583393137	4.60E-11	1.46E-09	11852	9398	6462	6437	12090	8725	3191	3026	3246	2646	3190	2066	sp	Q9UDY8	MALT1_HUMAN	32.536	627	333	23	721	2424	120	715	9.98E-68	244	Q9UDY8	reviewed	MALT1_HUMAN	Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (EC 3.4.22.-) (MALT lymphoma-associated translocation) (Paracaspase)	MALT1 MLT	Homo sapiens (Human)	824	GO:0001650; GO:0001923; GO:0002020; GO:0002096; GO:0002726; GO:0004175; GO:0004197; GO:0004842; GO:0005634; GO:0005737; GO:0005829; GO:0006508; GO:0006952; GO:0008233; GO:0009620; GO:0031398; GO:0031663; GO:0032449; GO:0032731; GO:0032743; GO:0032991; GO:0036094; GO:0042098; GO:0042113; GO:0042802; GO:0042981; GO:0043066; GO:0043123; GO:0043280; GO:0045087; GO:0048471; GO:0050852; GO:0050856; GO:0051092; GO:0051168; GO:0051603; GO:2000321
g9439	169.0144779	-1.183619157	0.318744508	-3.713378979	0.00020451	0.001192654	142	92	150	105	18	71	371	280	256	283	312	206	sp	Q1JP61	KDM8_BOVIN	28.358	268	166	11	94	840	145	405	2.79E-13	74.7	Q1JP61	reviewed	KDM8_BOVIN	Bifunctional peptidase and arginyl-hydroxylase JMJD5 (EC 1.14.11.73) (EC 3.4.-.-) (JmjC domain-containing protein 5) (Jumonji C domain-containing protein 5) (L-arginine (3R)-hydroxylase KDM8)	KDM8 JMJD5	Bos taurus (Bovine)	406	GO:0000086; GO:0001701; GO:0002039; GO:0003682; GO:0004175; GO:0004177; GO:0005634; GO:0005654; GO:0005694; GO:0005829; GO:0006508; GO:0031648; GO:0032922; GO:0035064; GO:0045892; GO:0045893; GO:0046872; GO:0048144; GO:0051864; GO:0106157; GO:1901796
g16352	171.2436713	2.758210018	1.002370042	2.751688402	0.00592889	0.020391414	228	747	363	72	11	259	53	19	0	27	37	225	sp	Q8IYS1	P20D2_HUMAN	44.11	399	198	6	115	1236	31	429	1.24E-77	250	Q8IYS1	reviewed	P20D2_HUMAN	Xaa-Arg dipeptidase (EC 3.4.13.4) (Beta-Ala-Lys dipeptidase)	PM20D2 ACY1L2	Homo sapiens (Human)	436	GO:0004180; GO:0005654; GO:0006508; GO:0016805; GO:0042802; GO:0051246
g7863	498.5672252	3.242787753	1.214354826	2.670379105	0.007576565	0.024888043	81	633	2188	0	21	1938	12	85	371	29	88	90	sp	O43895	XPP2_HUMAN	41.642	682	355	16	1	2031	28	671	1.98E-173	514	O43895	reviewed	XPP2_HUMAN	Xaa-Pro aminopeptidase 2 (EC 3.4.11.9) (Aminoacylproline aminopeptidase) (Membrane-bound aminopeptidase P) (Membrane-bound APP) (Membrane-bound AmP) (mAmP) (X-Pro aminopeptidase 2)	XPNPEP2	Homo sapiens (Human)	674	GO:0004177; GO:0005576; GO:0005886; GO:0006508; GO:0016020; GO:0046872; GO:0070006; GO:0070062; GO:0098552
g13659	123.9936476	1.33917735	0.39303967	3.407232026	0.000656253	0.003217527	183	122	98	266	134	82	118	102	69	107	74	37	sp	Q5XJY4	PARL_MOUSE	48.901	364	155	9	4	1059	28	372	8.01E-111	331	Q5XJY4	reviewed	PARL_MOUSE	"Presenilin-associated rhomboid-like protein, mitochondrial (EC 3.4.21.105) (Mitochondrial intramembrane-cleaving protease PARL) [Cleaved into: P-beta (Pbeta)]"	Parl Psarl	Mus musculus (Mouse)	377	GO:0004175; GO:0004252; GO:0005634; GO:0005739; GO:0005743; GO:0006465; GO:0006508; GO:0008053; GO:0016485; GO:0030162; GO:0033619; GO:0090201; GO:1901524; GO:1903214; GO:2000377; GO:2001243
g23669	213.1937419	5.775932491	2.263434025	2.551844864	0.010715422	0.032930321	221	2055	65	0	0	73	15	184	0	0	0	0	sp	O57460	TLL1_DANRE	47.826	46	22	2	462	596	228	272	1.59E-11	49.3	O57460	reviewed	TLL1_DANRE	Dorsal-ventral patterning tolloid-like protein 1 (EC 3.4.24.-) (Mini fin protein)	tll1 mfn tld tolloid	Danio rerio (Zebrafish) (Brachydanio rerio)	1022	GO:0001568; GO:0001707; GO:0001885; GO:0004222; GO:0005509; GO:0005576; GO:0005615; GO:0006508; GO:0008233; GO:0008237; GO:0008270; GO:0009953; GO:0016485; GO:0030513; GO:0035124; GO:0035162; GO:0036342; GO:0048264
g22278	441.4228191	1.724990205	0.42808718	4.02953016	5.59E-05	0.000386672	657	1563	692	202	106	663	285	315	202	245	164	209	sp	P37892	CBPE_LOPAM	48.984	443	200	9	1	1296	1	428	2.67E-134	397	P37892	reviewed	CBPE_LOPAM	Carboxypeptidase E (CPE) (EC 3.4.17.10) (Carboxypeptidase H) (CPH) (Enkephalin convertase) (Prohormone-processing carboxypeptidase)	cpe	Lophius americanus (American angler) (Anglerfish)	454	GO:0004181; GO:0005576; GO:0006508; GO:0008270; GO:0030658
g2743	94.59135317	-2.838799179	0.357057779	-7.950531658	1.86E-15	1.27E-13	17	18	32	33	4	19	309	237	179	234	142	140	sp	Q54P70	Y4757_DICDI	32.847	137	80	6	1624	2016	635	765	2.51E-08	61.6	Q54P70	reviewed	Y4757_DICDI	OTU domain-containing protein DDB_G0284757 (EC 3.1.2.-)	DDB_G0284757	Dictyostelium discoideum (Social amoeba)	766	GO:0004843; GO:0006508; GO:0016579
g10952	111.4007456	0.705896945	0.287642649	2.454076083	0.014124709	0.041283565	175	171	110	96	83	82	158	65	62	123	85	142	sp	E1C1R4	UBP47_CHICK	60.87	115	44	1	103	447	1253	1366	3.02E-33	127	E1C1R4	reviewed	UBP47_CHICK	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.4.19.12) (Deubiquitinating enzyme 47) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47)	USP47	Gallus gallus (Chicken)	1375	GO:0004843; GO:0005634; GO:0005737; GO:0005829; GO:0006284; GO:0006508; GO:0006974; GO:0016579; GO:0035520
g14094	172.6024442	-1.103905496	0.368166558	-2.998386116	0.002714136	0.010711342	105	69	192	47	32	143	355	294	321	259	238	247	sp	Q9CZR2	NALD2_MOUSE	28.879	651	356	19	304	2058	82	691	1.11E-66	237	Q9CZR2	reviewed	NALD2_MOUSE	N-acetylated-alpha-linked acidic dipeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase III) (GCPIII) (N-acetylaspartylglutamate peptidase II) (NAAG-peptidase II) (N-acetylated-alpha-linked acidic dipeptidase II) (NAALADase II)	Naalad2	Mus musculus (Mouse)	740	GO:0004180; GO:0004181; GO:0005886; GO:0006508; GO:0008233; GO:0016020; GO:0016805; GO:0046395; GO:0046872; GO:0050129
g14093	1430.711931	-0.658103689	0.248725257	-2.645906156	0.008147242	0.026365327	1092	945	1173	1218	383	1042	2548	1911	2090	1592	2677	1775	sp	O15484	CAN5_HUMAN	43.029	416	228	4	1	1233	228	639	8.58E-118	360	O15484	reviewed	CAN5_HUMAN	Calpain-5 (EC 3.4.22.-) (Calpain htra-3) (New calpain 3) (nCL-3)	CAPN5 NCL3	Homo sapiens (Human)	640	GO:0004198; GO:0005737; GO:0005925; GO:0006508; GO:0007165; GO:0009986; GO:0045202; GO:0070062
g14092	745.8273516	-0.639304317	0.25966678	-2.462018124	0.013815769	0.040545358	535	504	500	626	268	587	1284	1065	1012	876	1562	698	sp	O15484	CAN5_HUMAN	53.333	210	98	0	10	639	5	214	3.16E-77	247	O15484	reviewed	CAN5_HUMAN	Calpain-5 (EC 3.4.22.-) (Calpain htra-3) (New calpain 3) (nCL-3)	CAPN5 NCL3	Homo sapiens (Human)	640	GO:0004198; GO:0005737; GO:0005925; GO:0006508; GO:0007165; GO:0009986; GO:0045202; GO:0070062
g23157	2249.646717	4.502855998	0.662382606	6.797968364	1.06E-11	3.78E-10	4066	13090	2993	155	1185	3017	311	145	122	260	103	303	sp	P80646	CTRB_GADMO	32.468	231	136	9	1570	2229	18	239	1.13E-22	102	P80646	reviewed	CTRB_GADMO	Chymotrypsin B (EC 3.4.21.1) [Cleaved into: Chymotrypsin B chain A; Chymotrypsin B chain B]		Gadus morhua (Atlantic cod)	245	GO:0004252; GO:0005576; GO:0006508; GO:0007586
g588	3188.363266	4.903979129	1.116000874	4.394243091	1.11E-05	9.72E-05	391	1791	10373	44	128	19193	17	150	413	56	315	340	sp	P80146	SEPR_THESR	51.235	324	152	4	160	1119	88	409	7.63E-99	302	P80146	reviewed	SEPR_THESR	Extracellular serine proteinase (EC 3.4.21.-)		Thermus sp. (strain Rt41A)	410	GO:0004252; GO:0005615; GO:0006508
g21213	2922.097767	4.43699951	0.883047663	5.024643286	5.04E-07	6.36E-06	2413	10420	4700	69	865	11456	41	369	372	99	546	296	sp	Q5G266	NETR_TRAPH	37.445	227	130	6	580	1239	280	501	2.79E-38	150	Q5G266	reviewed	NETR_TRAPH	Neurotrypsin (EC 3.4.21.-) (Serine protease 12)	PRSS12	Trachypithecus phayrei (Phayre's leaf monkey)	875	GO:0004252; GO:0005886; GO:0006508; GO:0006887; GO:0030424; GO:0030425; GO:0043083; GO:0043195
g21210	6536.648633	7.382964049	0.756820167	9.755242222	1.75E-22	3.18E-20	8741	8039	3917	572	19647	14783	97	87	14	21	207	79	sp	G5ECS8	ADT1_CAEEL	44.66	103	50	3	79	369	1263	1364	1.65E-12	67	G5ECS8	reviewed	ADT1_CAEEL	A disintegrin and metalloproteinase with thrombospondin motifs adt-1 (ADAMTS adt-1) (EC 3.4.24.-)	adt-1 C02B4.1	Caenorhabditis elegans	1461	GO:0004222; GO:0005576; GO:0006508; GO:0030198; GO:0031012; GO:0046872
g4026	4567.555525	-2.613883718	0.352300453	-7.419473053	1.18E-13	5.92E-12	837	1274	2321	536	561	1302	12906	12040	6745	6784	11178	7537	sp	Q9VT65	CANB_DROME	46.132	698	342	12	22	2067	246	925	0	604	Q9VT65	reviewed	CANB_DROME	Calpain-B (EC 3.4.22.-) (Calcium-activated neutral proteinase B) (CANP B) [Cleaved into: Calpain-B catalytic subunit 1; Calpain-B catalytic subunit 2]	CalpB CG8107	Drosophila melanogaster (Fruit fly)	925	GO:0004198; GO:0005509; GO:0005737; GO:0006508; GO:0007298; GO:0016020; GO:0016322; GO:0016540
g13110	626.9234167	3.453132783	0.945553636	3.651969231	0.000260237	0.001467084	1869	3701	265	29	391	308	16	647	25	11	73	18	sp	P17538	CTRB1_HUMAN	39.516	248	127	9	127	858	32	260	1.41E-44	164	P17538	reviewed	CTRB1_HUMAN	Chymotrypsinogen B (EC 3.4.21.1) [Cleaved into: Chymotrypsin B chain A; Chymotrypsin B chain B; Chymotrypsin B chain C]	CTRB1 CTRB	Homo sapiens (Human)	263	GO:0004252; GO:0005576; GO:0006508; GO:0007586
g23741	125.6294874	-0.963530685	0.357018387	-2.698826503	0.006958444	0.023237892	96	102	144	86	18	36	266	166	139	207	192	237	sp	Q9CXY9	GPI8_MOUSE	63.603	272	96	1	1	816	85	353	2.44E-130	379	Q9CXY9	reviewed	GPI8_MOUSE	GPI-anchor transamidase (GPI transamidase) (EC 3.-.-.-) (Phosphatidylinositol-glycan biosynthesis class K protein) (PIG-K)	Pigk	Mus musculus (Mouse)	395	GO:0003923; GO:0006508; GO:0016255; GO:0042765
g19522	568.7991699	1.537356299	0.42905503	3.583121492	0.000339513	0.001834899	791	892	897	133	572	1007	594	259	210	430	275	433	sp	Q8NFA0	UBP32_HUMAN	55.593	885	303	15	256	2886	516	1318	0	967	Q8NFA0	reviewed	UBP32_HUMAN	Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.4.19.12) (Deubiquitinating enzyme 32) (Renal carcinoma antigen NY-REN-60) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32)	USP32 USP10	Homo sapiens (Human)	1604	GO:0000139; GO:0004843; GO:0005509; GO:0005794; GO:0005829; GO:0006508; GO:0016579; GO:1904263
g6550	213.7703264	1.447381147	0.312415414	4.632873672	3.61E-06	3.64E-05	374	292	297	166	265	178	220	137	86	140	87	185	sp	A3KQS4	MINY1_DANRE	53.571	308	138	1	190	1098	149	456	4.11E-111	340	A3KQS4	reviewed	MINY1_DANRE	Ubiquitin carboxyl-terminal hydrolase MINDY-1 (EC 3.4.19.12) (Deubiquitinating enzyme MINDY-1) (Protein FAM63A)	mindy1 fam63a si:ch211-210h11.5	Danio rerio (Zebrafish) (Brachydanio rerio)	520	GO:0004843; GO:0006508; GO:0036435; GO:1990380
g12005	80.48086137	3.207250155	1.048535569	3.05879004	0.002222328	0.009064705	54	223	255	15	0	243	32	41	45	10	0	14	sp	Q9W436	NEP_DROME	46.056	393	208	2	16	1185	458	849	1.11E-129	396	Q9W436	reviewed	NEP_DROME	Neprilysin-1 (EC 3.4.24.11)	Nep1 CG5905	Drosophila melanogaster (Fruit fly)	849	GO:0004222; GO:0005886; GO:0006508; GO:0008237; GO:0016020; GO:0046872
g3583	91.40387763	-2.350345773	0.433379088	-5.423302232	5.85E-08	9.40E-07	42	12	44	26	7	28	198	205	79	149	227	243	sp	Q7L266	ASGL1_HUMAN	51.325	302	136	5	61	957	12	305	3.02E-83	257	Q7L266	reviewed	ASGL1_HUMAN	Isoaspartyl peptidase/L-asparaginase (EC 3.4.19.5) (EC 3.5.1.1) (Asparaginase-like protein 1) (Beta-aspartyl-peptidase) (Isoaspartyl dipeptidase) (L-asparagine amidohydrolase) [Cleaved into: Isoaspartyl peptidase/L-asparaginase alpha chain; Isoaspartyl peptidase/L-asparaginase beta chain]	ASRGL1 ALP CRASH	Homo sapiens (Human)	308	GO:0001917; GO:0004067; GO:0005634; GO:0005737; GO:0005829; GO:0006508; GO:0008798; GO:0033345
g9400	476.3248566	0.526669312	0.174744291	3.013942885	0.002578763	0.010263919	619	579	621	380	240	535	577	499	410	471	357	532	sp	O76031	CLPX_HUMAN	67.093	313	66	5	286	1158	103	400	6.87E-118	347	O76031	reviewed	CLPX_HUMAN	"ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial"	CLPX	Homo sapiens (Human)	633	GO:0005524; GO:0005654; GO:0005739; GO:0005743; GO:0005759; GO:0005829; GO:0006508; GO:0008270; GO:0009368; GO:0009841; GO:0016504; GO:0016887; GO:0042645; GO:0046034; GO:0046983; GO:0051082; GO:0051603; GO:0140662
g5241	1478.760558	3.22041263	1.132965663	2.842462694	0.004476647	0.016234429	565	1693	6375	11	86	5743	12	217	962	27	423	273	sp	Q95M12	LGMN_BOVIN	48.798	416	207	5	67	1305	17	429	1.12E-138	407	Q95M12	reviewed	LGMN_BOVIN	"Legumain (EC 3.4.22.34) (Asparaginyl endopeptidase) (Protease, cysteine 1)"	LGMN PRSC1	Bos taurus (Bovine)	433	GO:0003014; GO:0004197; GO:0005764; GO:0006508; GO:0006624; GO:0019886; GO:0032801; GO:0043202; GO:0051603; GO:1901185
g8177	3582.092509	0.887325368	0.259631953	3.417627754	0.000631694	0.003115517	4780	4250	6166	4374	1542	3804	4456	2418	3188	2221	3839	2207	sp	Q9DEX3	CATD_CLUHA	55.409	379	155	4	58	1164	21	395	3.58E-150	433	Q9DEX3	reviewed	CATD_CLUHA	Cathepsin D (EC 3.4.23.5)	ctsd	Clupea harengus (Atlantic herring)	396	GO:0004190; GO:0005764; GO:0006508
g22714	1642.893735	2.413452375	0.957741021	2.519942577	0.011737398	0.035514535	444	1326	6938	73	94	6087	354	374	1189	87	641	885	sp	P07858	CATB_HUMAN	45.223	314	110	9	64	843	26	331	1.56E-70	224	P07858	reviewed	CATB_HUMAN	Cathepsin B (EC 3.4.22.1) (APP secretase) (APPS) (Cathepsin B1) [Cleaved into: Cathepsin B light chain; Cathepsin B heavy chain]	CTSB CPSB	Homo sapiens (Human)	339	GO:0004197; GO:0005518; GO:0005576; GO:0005615; GO:0005764; GO:0006508; GO:0006590; GO:0008233; GO:0008234; GO:0009897; GO:0016324; GO:0030574; GO:0030855; GO:0036021; GO:0042470; GO:0042981; GO:0043394; GO:0046697; GO:0046718; GO:0048471; GO:0051603; GO:0062023; GO:0070062; GO:0097067; GO:1904090; GO:1904813
g23904	22775.51883	2.325662884	0.413847066	5.619619122	1.91E-08	3.44E-07	24509	10510	16432	43861	42231	38818	10359	8848	5671	4913	9534	6869	sp	Q3SYW2	CO2_BOVIN	27.284	777	430	31	673	2778	25	741	3.78E-60	223	Q3SYW2	reviewed	CO2_BOVIN	Complement C2 (EC 3.4.21.43) (C3/C5 convertase) [Cleaved into: Complement C2b fragment; Complement C2a fragment]	C2	Bos taurus (Bovine)	750	GO:0004252; GO:0005576; GO:0006508; GO:0006956; GO:0006958; GO:0009617; GO:0045087; GO:0046872
g6127	39.84522166	-2.388670713	0.914210401	-2.612823821	0.008979758	0.028594093	0	9	48	0	9	6	115	66	76	118	74	42	sp	P20825	POL2_DROME	33.846	260	164	3	958	1734	376	628	1.04E-36	150	P20825	reviewed	POL2_DROME	Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	pol	Drosophila melanogaster (Fruit fly)	1059	GO:0003676; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575
g12155	7205.490786	4.391812498	1.171168189	3.749941757	0.000176876	0.00105502	391	6215	28873	46	192	37024	68	312	1565	210	1261	854	sp	P32822	TRYB_RAT	33.333	231	136	6	70	738	24	244	1.80E-26	106	P32822	reviewed	TRYB_RAT	Trypsin V-B (EC 3.4.21.4)		Rattus norvegicus (Rat)	246	GO:0004252; GO:0005615; GO:0006508; GO:0007586; GO:0046872
g19768	223.9509691	0.813007722	0.261749479	3.106052877	0.001896028	0.007953562	359	233	225	327	131	213	410	184	162	147	191	143	sp	P87362	BLMH_CHICK	54.725	455	178	4	10	1308	6	454	3.13E-178	508	P87362	reviewed	BLMH_CHICK	Bleomycin hydrolase (BH) (BLM hydrolase) (BMH) (EC 3.4.22.40) (Aminopeptidase H)	BLMH	Gallus gallus (Chicken)	455	GO:0004177; GO:0004197; GO:0005737; GO:0006508; GO:0008234; GO:0009636; GO:0043418; GO:0070005
g24087	266.4495201	3.428313339	1.110318526	3.087684533	0.002017225	0.008366491	138	814	701	11	0	1014	14	51	89	9	50	89	sp	P12821	ACE_HUMAN	47.126	609	309	7	70	1875	638	1240	0	600	P12821	reviewed	ACE_HUMAN	"Angiotensin-converting enzyme (ACE) (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (CD antigen CD143) [Cleaved into: Angiotensin-converting enzyme, soluble form]"	ACE DCP DCP1	Homo sapiens (Human)	1306	GO:0001666; GO:0001822; GO:0001974; GO:0002003; GO:0002019; GO:0002446; GO:0002474; GO:0003081; GO:0003084; GO:0003779; GO:0004175; GO:0004180; GO:0004222; GO:0005516; GO:0005576; GO:0005615; GO:0005764; GO:0005768; GO:0005886; GO:0006508; GO:0007283; GO:0007565; GO:0008217; GO:0008233; GO:0008237; GO:0008238; GO:0008240; GO:0008241; GO:0008270; GO:0008584; GO:0009410; GO:0009792; GO:0009897; GO:0009925; GO:0010608; GO:0010629; GO:0010814; GO:0010815; GO:0014910; GO:0019229; GO:0031100; GO:0031404; GO:0031434; GO:0031526; GO:0031667; GO:0031711; GO:0032496; GO:0032943; GO:0034616; GO:0038166; GO:0042310; GO:0042445; GO:0042447; GO:0042755; GO:0043065; GO:0043171; GO:0045907; GO:0046325; GO:0048167; GO:0048286; GO:0050435; GO:0050482; GO:0050769; GO:0051019; GO:0060047; GO:0060177; GO:0060218; GO:0060978; GO:0070062; GO:0070573; GO:0071333; GO:0071548; GO:0071838; GO:0086091; GO:0090281; GO:0097066; GO:0097225; GO:0097746; GO:1901363; GO:1902033; GO:1903597; GO:1904045; GO:2000170
g5949	665.3909613	2.331026158	0.901324829	2.586222062	0.009703439	0.030404932	236	480	3528	49	13	1897	293	222	198	275	152	434	sp	P15684	AMPN_RAT	42.484	805	430	15	4	2376	176	961	0	634	P15684	reviewed	AMPN_RAT	Aminopeptidase N (AP-N) (rAPN) (EC 3.4.11.2) (Alanyl aminopeptidase) (Aminopeptidase M) (AP-M) (Kidney Zn peptidase) (KZP) (Microsomal aminopeptidase) (CD antigen CD13)	Anpep	Rattus norvegicus (Rat)	965	GO:0001525; GO:0004177; GO:0005615; GO:0005737; GO:0005793; GO:0005886; GO:0006508; GO:0008270; GO:0009897; GO:0016485; GO:0030154; GO:0031526; GO:0042277; GO:0043171; GO:0070006; GO:0070062; GO:0072237
g4204	198.5555175	3.351983301	1.2165997	2.755206418	0.005865512	0.020217744	85	200	796	5	12	828	13	10	170	8	0	63	sp	Q9Y3Q0	NALD2_HUMAN	45	740	390	11	55	2238	6	740	0	660	Q9Y3Q0	reviewed	NALD2_HUMAN	N-acetylated-alpha-linked acidic dipeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase III) (GCPIII) (N-acetylated-alpha-linked acidic dipeptidase II) (NAALADase II)	NAALAD2	Homo sapiens (Human)	740	GO:0004180; GO:0004181; GO:0005886; GO:0006508; GO:0008236; GO:0008239; GO:0016020; GO:0016805; GO:0046872
g623	202.0852987	-2.660378243	0.477787536	-5.568119805	2.58E-08	4.49E-07	38	10	10	88	45	51	117	243	44	964	635	463	sp	O00602	FCN1_HUMAN	57.343	143	60	1	88	513	184	326	1.64E-51	170	O00602	reviewed	FCN1_HUMAN	Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin)	FCN1 FCNM	Homo sapiens (Human)	326	GO:0001664; GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005576; GO:0005581; GO:0005615; GO:0005886; GO:0006508; GO:0007186; GO:0009897; GO:0030246; GO:0032757; GO:0033691; GO:0034394; GO:0034774; GO:0038187; GO:0043654; GO:0046597; GO:0046872; GO:0062023; GO:0097367; GO:1903028; GO:1904813; GO:1905370
g19175	432.7627536	4.275857319	1.320879514	3.237128953	0.001207388	0.005444603	85	371	1095	0	41	2613	0	17	62	10	131	65	sp	P15088	CBPA3_HUMAN	39.516	124	61	3	1	351	297	413	2.48E-19	85.1	P15088	reviewed	CBPA3_HUMAN	Mast cell carboxypeptidase A (MC-CPA) (EC 3.4.17.1) (Carboxypeptidase A3)	CPA3	Homo sapiens (Human)	417	GO:0002002; GO:0004181; GO:0005576; GO:0005615; GO:0006508; GO:0008270; GO:0030133; GO:0030141; GO:0062023
g9657	1134.883493	1.528480318	0.477011241	3.204285738	0.00135398	0.005989853	1308	525	444	1395	2540	1360	588	580	387	468	1137	403	sp	A0A386CAB9	NLRP1_DANRE	23.743	358	208	12	544	1560	252	563	9.24E-11	69.7	A0A386CAB9	reviewed	NLRP1_DANRE	"NACHT, LRR and PYD domains-containing protein 1 homolog (EC 3.4.-.-) [Cleaved into: NACHT, LRR and PYD domains-containing protein 1, C-terminus (NLRP1-CT); NACHT, LRR and PYD domains-containing protein 1, N-terminus (NLRP1-NT)]"	nlrp1 si:ch211-66k16.28	Danio rerio (Zebrafish) (Brachydanio rerio)	1355	GO:0002221; GO:0005524; GO:0005737; GO:0006508; GO:0006954; GO:0008233; GO:0012501; GO:0032731; GO:0042981; GO:0045087; GO:0050729; GO:0061702; GO:0072558
g18370	82.27979451	-2.048434579	0.502817034	-4.073916437	4.62E-05	0.000330711	45	28	25	61	7	6	178	150	122	152	233	119	sp	B5DEQ3	XPP3_RAT	55.23	239	105	1	40	756	268	504	3.43E-99	301	B5DEQ3	reviewed	XPP3_RAT	Xaa-Pro aminopeptidase 3 (X-Pro aminopeptidase 3) (EC 3.4.11.9) (Aminopeptidase P3) (APP3)	Xpnpep3	Rattus norvegicus (Rat)	506	GO:0003094; GO:0004177; GO:0005737; GO:0005739; GO:0006508; GO:0016485; GO:0030145; GO:0042803; GO:0070006
g18371	82.5494687	-1.440465774	0.338315611	-4.257757334	2.06E-05	0.00016625	26	51	35	66	20	32	143	181	115	197	93	144	sp	Q9NQH7	XPP3_HUMAN	54.225	142	64	1	232	654	41	182	5.25E-49	171	Q9NQH7	reviewed	XPP3_HUMAN	Xaa-Pro aminopeptidase 3 (X-Pro aminopeptidase 3) (EC 3.4.11.9) (Aminopeptidase P3) (APP3)	XPNPEP3	Homo sapiens (Human)	507	GO:0003094; GO:0004177; GO:0005737; GO:0005739; GO:0005829; GO:0006508; GO:0016485; GO:0030145; GO:0042803; GO:0070006
g3861	12046.64949	4.923644542	1.162440411	4.235610269	2.28E-05	0.000181233	809	11392	51277	65	346	60116	73	608	2336	317	975	816	sp	P00767	CTRB_BOVIN	37.109	256	113	7	67	723	1	245	1.07E-43	150	P00767	reviewed	CTRB_BOVIN	Chymotrypsinogen B (EC 3.4.21.1) [Cleaved into: Chymotrypsin B chain A; Chymotrypsin B chain B; Chymotrypsin B chain C]		Bos taurus (Bovine)	245	GO:0004252; GO:0005576; GO:0006508; GO:0007586
g18940	43.07194924	-5.407472782	1.10366543	-4.899557994	9.61E-07	1.12E-05	7	4	10	0	0	0	198	3	103	66	29	224	sp	P04323	POL3_DROME	37.755	294	150	4	1	795	334	623	5.63E-59	209	P04323	reviewed	POL3_DROME	Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	pol	Drosophila melanogaster (Fruit fly)	1058	GO:0003676; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575
g22159	12573.87022	3.388775065	0.651639667	5.200381802	1.99E-07	2.78E-06	9537	4856	10730	15497	25305	36431	5790	3341	2823	855	524	1856	sp	Q99PW6	MMP24_RAT	35.095	473	239	16	148	1401	83	542	2.27E-77	257	Q99PW6	reviewed	MMP24_RAT	Matrix metalloproteinase-24 (MMP-24) (EC 3.4.24.-) (Membrane-type matrix metalloproteinase 5) (MT-MMP 5) (MTMMP5) (Membrane-type-5 matrix metalloproteinase) (MT5-MMP) (MT5MMP) [Cleaved into: Processed matrix metalloproteinase-24]	Mmp24 Mt5mmp	Rattus norvegicus (Rat)	618	GO:0004222; GO:0005615; GO:0005886; GO:0006508; GO:0008233; GO:0008270; GO:0010001; GO:0030198; GO:0030574; GO:0031012; GO:0032588; GO:0044331; GO:0045296; GO:0050965; GO:0097150; GO:0098742
g21444	165.7426044	-1.580427369	0.635911323	-2.485295216	0.012944404	0.038406033	33	43	171	6	32	145	487	394	211	169	260	320	sp	Q9P2N4	ATS9_HUMAN	31.041	1018	524	31	4	2787	995	1924	2.60E-127	427	Q9P2N4	reviewed	ATS9_HUMAN	A disintegrin and metalloproteinase with thrombospondin motifs 9 (ADAM-TS 9) (ADAM-TS9) (ADAMTS-9) (EC 3.4.24.-)	ADAMTS9 KIAA1312	Homo sapiens (Human)	1935	GO:0003179; GO:0003229; GO:0004222; GO:0005615; GO:0005783; GO:0006508; GO:0008237; GO:0008270; GO:0009617; GO:0009986; GO:0010596; GO:0015031; GO:0016192; GO:0030198; GO:0030318; GO:0031012; GO:0035909; GO:0043231; GO:0045636; GO:0090673; GO:1903671
g17386	1663.568638	1.172574312	0.3536943	3.315219704	0.000915711	0.004273319	2712	976	1247	2188	2265	1763	1460	1252	1323	1010	1185	894	sp	P23004	QCR2_BOVIN	41.084	443	256	4	49	1365	12	453	1.66E-115	349	P23004	reviewed	QCR2_BOVIN	"Cytochrome b-c1 complex subunit 2, mitochondrial (Complex III subunit 2) (Core protein II) (Ubiquinol-cytochrome-c reductase complex core protein 2)"	UQCRC2	Bos taurus (Bovine)	453	GO:0004222; GO:0005739; GO:0005743; GO:0006508; GO:0046872; GO:0070469
g12267	178.3992408	2.009542889	0.67238445	2.988681385	0.002801841	0.011005105	151	525	355	98	21	426	128	95	10	81	68	148	sp	P52948	NUP98_HUMAN	34.615	234	127	8	85	741	62	284	1.49E-19	95.9	P52948	reviewed	NUP98_HUMAN	Nuclear pore complex protein Nup98-Nup96 (EC 3.4.21.-) [Cleaved into: Nuclear pore complex protein Nup98 (98 kDa nucleoporin) (Nucleoporin Nup98) (Nup98); Nuclear pore complex protein Nup96 (96 kDa nucleoporin) (Nucleoporin Nup96) (Nup96)]	NUP98 ADAR2	Homo sapiens (Human)	1817	GO:0000973; GO:0003713; GO:0003723; GO:0003729; GO:0005635; GO:0005643; GO:0005654; GO:0005829; GO:0006405; GO:0006508; GO:0006606; GO:0006913; GO:0006999; GO:0008139; GO:0008236; GO:0016604; GO:0017056; GO:0031080; GO:0031965; GO:0034398; GO:0034399; GO:0042405; GO:0044614; GO:0044615; GO:0048026; GO:0051028; GO:0051292; GO:0140693; GO:1990841; GO:1990904
g8609	436.3546935	2.676281568	0.732137009	3.65543817	0.000256743	0.001449754	282	267	281	1693	806	176	154	95	66	8	287	50	sp	P59509	ATS19_MOUSE	32	150	80	6	82	480	809	953	1.90E-15	73.9	P59509	reviewed	ATS19_MOUSE	A disintegrin and metalloproteinase with thrombospondin motifs 19 (ADAM-TS 19) (ADAM-TS19) (ADAMTS-19) (EC 3.4.24.-)	Adamts19	Mus musculus (Mouse)	1210	GO:0003180; GO:0004222; GO:0005576; GO:0006508; GO:0030198; GO:0030199; GO:0031012; GO:0046872
g5296	211.0419451	-0.654071871	0.183330234	-3.567725067	0.000360094	0.001931017	160	178	175	120	93	125	359	374	260	385	260	245	sp	Q9UI42	CBPA4_HUMAN	28.371	356	203	16	37	1035	61	387	4.17E-21	98.6	Q9UI42	reviewed	CBPA4_HUMAN	Carboxypeptidase A4 (EC 3.4.17.-) (Carboxypeptidase A3)	CPA4 CPA3 UNQ694/PRO1339	Homo sapiens (Human)	421	GO:0004181; GO:0005615; GO:0006508; GO:0008270; GO:0042447; GO:0043171
g619	724.474935	5.369885956	1.399440172	3.837167221	0.000124462	0.000782111	107	844	3751	14	43	2912	0	9	198	12	0	49	sp	P21128	ENDOU_HUMAN	32.353	408	240	10	85	1269	24	408	9.95E-64	213	P21128	reviewed	ENDOU_HUMAN	Uridylate-specific endoribonuclease (EC 4.6.1.-) (Placental protein 11) (PP11) (Protein endoU)	ENDOU	Homo sapiens (Human)	410	GO:0003723; GO:0004521; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0005886; GO:0006508; GO:0006955; GO:0007565; GO:0008083; GO:0008236; GO:0016441; GO:0016829; GO:0030145; GO:0030247; GO:0050995
g6237	1063.729383	1.367147045	0.43411744	3.149256211	0.001636866	0.007011311	1088	3108	1723	445	381	1723	894	665	486	566	892	723	sp	Q1JPJ2	XPP1_BOVIN	33.572	697	371	19	175	2238	6	619	6.32E-112	357	Q1JPJ2	reviewed	XPP1_BOVIN	"Xaa-Pro aminopeptidase 1 (EC 3.4.11.9) (Aminoacylproline aminopeptidase) (Cytosolic aminopeptidase P) (Soluble aminopeptidase P) (sAmp) (X-Pro aminopeptidase 1) (X-prolyl aminopeptidase 1, soluble)"	XPNPEP1	Bos taurus (Bovine)	623	GO:0005829; GO:0006508; GO:0010815; GO:0030145; GO:0043069; GO:0070006
g6236	624.1844029	2.448317534	0.945602976	2.58916014	0.009621034	0.03022903	172	1070	1610	14	25	2724	175	256	257	63	172	417	sp	Q6P1B1	XPP1_MOUSE	46.988	166	81	3	4	489	457	619	7.44E-48	168	Q6P1B1	reviewed	XPP1_MOUSE	"Xaa-Pro aminopeptidase 1 (EC 3.4.11.9) (Aminoacylproline aminopeptidase) (Cytosolic aminopeptidase P) (Soluble aminopeptidase P) (sAmp) (X-Pro aminopeptidase 1) (X-prolyl aminopeptidase 1, soluble)"	Xpnpep1	Mus musculus (Mouse)	623	GO:0004177; GO:0005737; GO:0005829; GO:0006508; GO:0010815; GO:0030145; GO:0043069; GO:0070006
g6235	1392.247007	2.736930938	0.953197689	2.871315122	0.004087678	0.015013085	374	2813	3731	52	39	5962	413	529	435	92	213	880	sp	Q4WUD3	AMPP1_ASPFU	41.845	466	222	12	184	1551	45	471	8.03E-95	305	Q4WUD3	reviewed	AMPP1_ASPFU	Probable Xaa-Pro aminopeptidase P (AMPP) (Aminopeptidase P) (EC 3.4.11.9) (Aminoacylproline aminopeptidase) (Prolidase)	ampp AFUA_5G08050	Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata)	654	GO:0005737; GO:0006508; GO:0046872; GO:0070006
g6234	57.8551162	2.358620075	0.933191541	2.527476912	0.011488538	0.034902348	105	266	70	10	0	116	35	14	7	9	14	51	sp	F1NV61	CASP7_CHICK	46.125	271	134	3	277	1065	43	309	2.64E-78	246	F1NV61	reviewed	CASP7_CHICK	Caspase-7 (CASP-7) (EC 3.4.22.60) [Cleaved into: Caspase-7 subunit p20; Caspase-7 subunit p11]	CASP7	Gallus gallus (Chicken)	309	GO:0003723; GO:0004190; GO:0005615; GO:0005634; GO:0005737; GO:0005829; GO:0006508; GO:0042742; GO:0043525; GO:0070227; GO:0097153; GO:0097194; GO:0097200; GO:1905686
g1564	174.1072762	-2.468223822	0.427655832	-5.77151915	7.86E-09	1.55E-07	46	76	87	65	16	9	551	357	219	430	315	320	sp	P69527	AMPO_RAT	34.762	840	424	14	16	2247	11	822	4.10E-146	451	P69527	reviewed	AMPO_RAT	Aminopeptidase O (AP-O) (EC 3.4.11.-)	Aopep Onpep	Rattus norvegicus (Rat)	822	GO:0005730; GO:0006508; GO:0008270; GO:0070006
g21824	2345.75	3.605657994	1.046494278	3.445463649	0.000570081	0.002864008	939	5499	6318	25	95	10422	64	385	685	44	574	606	sp	A8K7I4	CLCA1_HUMAN	35.938	832	465	23	79	2541	23	797	1.50E-137	439	A8K7I4	reviewed	CLCA1_HUMAN	Calcium-activated chloride channel regulator 1 (EC 3.4.-.-) (Calcium-activated chloride channel family member 1) (hCLCA1) (Calcium-activated chloride channel protein 1) (CaCC-1) (hCaCC-1)	CLCA1 CACC1	Homo sapiens (Human)	914	GO:0004222; GO:0005229; GO:0005254; GO:0005576; GO:0005886; GO:0005902; GO:0006508; GO:0006816; GO:0034220; GO:0042589; GO:0046872; GO:0071456
g21825	14.06734284	4.694553535	1.762440265	2.663666751	0.007729409	0.025293851	21	48	26	0	0	46	0	10	10	0	0	0	sp	Q6Q473	CLA4A_MOUSE	32.609	966	570	31	79	2934	23	921	4.39E-142	451	Q6Q473	reviewed	CLA4A_MOUSE	"Calcium-activated chloride channel regulator 4A (EC 3.4.-.-) (Calcium-activated chloride channel regulator 6) (mClca6) [Cleaved into: Calcium-activated chloride channel regulator 4A, 110 kDa form; Calcium-activated chloride channel regulator 4A, 30 kDa form]"	Clca4a Clca6	Mus musculus (Mouse)	924	GO:0005229; GO:0005254; GO:0005576; GO:0005886; GO:0006508; GO:0006821; GO:0008237; GO:0015276; GO:0016324; GO:0046872
g21827	1184.090109	4.417198342	0.998685772	4.423011188	9.73E-06	8.67E-05	619	4722	2634	32	60	4348	20	381	156	14	129	73	sp	Q9D7Z6	CLCA1_MOUSE	31.803	915	524	35	124	2796	25	863	1.71E-108	364	Q9D7Z6	reviewed	CLCA1_MOUSE	Calcium-activated chloride channel regulator 1 (EC 3.4.-.-) (Calcium-activated chloride channel family member 3) (mCLCA3) (Protein gob-5)	Clca1 Clca3 Gob5	Mus musculus (Mouse)	913	GO:0005229; GO:0005254; GO:0005576; GO:0005886; GO:0005902; GO:0006508; GO:0006816; GO:0006821; GO:0008237; GO:0016020; GO:0030141; GO:0042589; GO:0046872; GO:0071456
g21822	273.6978798	4.432179673	1.455677019	3.044754856	0.0023287	0.009433942	97	322	821	17	0	1485	0	84	44	12	0	38	sp	Q6Q473	CLA4A_MOUSE	31.148	915	543	31	85	2706	20	888	3.64E-111	369	Q6Q473	reviewed	CLA4A_MOUSE	"Calcium-activated chloride channel regulator 4A (EC 3.4.-.-) (Calcium-activated chloride channel regulator 6) (mClca6) [Cleaved into: Calcium-activated chloride channel regulator 4A, 110 kDa form; Calcium-activated chloride channel regulator 4A, 30 kDa form]"	Clca4a Clca6	Mus musculus (Mouse)	924	GO:0005229; GO:0005254; GO:0005576; GO:0005886; GO:0006508; GO:0006821; GO:0008237; GO:0015276; GO:0016324; GO:0046872
g3194	1425.557223	-2.278505391	0.594594067	-3.832035193	0.000127088	0.000796871	125	123	780	501	85	1003	5178	3467	1884	3451	1457	2401	sp	P16444	DPEP1_HUMAN	51.832	382	162	7	130	1272	20	380	4.79E-136	399	P16444	reviewed	DPEP1_HUMAN	Dipeptidase 1 (EC 3.4.13.19) (Beta-lactamase) (EC 3.5.2.6) (Dehydropeptidase-I) (Microsomal dipeptidase) (Renal dipeptidase) (hRDP)	DPEP1 MDP RDP	Homo sapiens (Human)	411	GO:0005615; GO:0005654; GO:0005886; GO:0006508; GO:0006749; GO:0006751; GO:0006954; GO:0008235; GO:0008270; GO:0008800; GO:0016324; GO:0016805; GO:0016999; GO:0030054; GO:0030336; GO:0030593; GO:0031528; GO:0034235; GO:0043027; GO:0043066; GO:0043154; GO:0045177; GO:0050667; GO:0070062; GO:0070573; GO:0071277; GO:0071466; GO:0071732; GO:0072340; GO:0072341; GO:0098552; GO:1901749
g3207	3666.738113	2.147190563	0.352705703	6.087768201	1.14E-09	2.74E-08	6655	3128	3519	2373	6734	5693	1856	1217	1197	2233	1400	1732	sp	Q9NQC7	CYLD_HUMAN	44.356	505	245	12	2902	4383	470	949	1.87E-121	407	Q9NQC7	reviewed	CYLD_HUMAN	Ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.4.19.12) (Deubiquitinating enzyme CYLD) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD)	CYLD CYLD1 KIAA0849 HSPC057	Homo sapiens (Human)	956	GO:0004843; GO:0005813; GO:0005819; GO:0005829; GO:0005874; GO:0005886; GO:0006508; GO:0007346; GO:0008270; GO:0010803; GO:0016055; GO:0016579; GO:0019901; GO:0032088; GO:0032480; GO:0035872; GO:0036064; GO:0043369; GO:0045087; GO:0045577; GO:0045582; GO:0046329; GO:0048471; GO:0048872; GO:0050727; GO:0050728; GO:0050862; GO:0060544; GO:0061578; GO:0061815; GO:0070064; GO:0070266; GO:0070507; GO:0070536; GO:0090090; GO:0097542; GO:1901026; GO:1901223; GO:1902017; GO:1903753; GO:1903829; GO:1990108; GO:1990380; GO:2000493; GO:2001238; GO:2001242
g19820	5.364271118	3.547006584	1.457226943	2.434079744	0.014929706	0.043110836	7	8	12	14	6	0	7	6	0	0	0	0	sp	O75636	FCN3_HUMAN	42.174	230	106	10	670	1344	92	299	1.28E-41	152	O75636	reviewed	FCN3_HUMAN	Ficolin-3 (Collagen/fibrinogen domain-containing lectin 3 p35) (Collagen/fibrinogen domain-containing protein 3) (Hakata antigen)	FCN3 FCNH HAKA1	Homo sapiens (Human)	299	GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005576; GO:0005581; GO:0005615; GO:0006508; GO:0006956; GO:0009897; GO:0030246; GO:0043654; GO:0046597; GO:0046872; GO:0051607; GO:0062023; GO:0072562; GO:0097367; GO:1902679; GO:1903028; GO:1905370
g1917	1446.970262	-2.704297045	0.48941083	-5.525617498	3.28E-08	5.58E-07	428	284	438	91	461	108	4358	2333	1483	4341	3303	2843	sp	Q9UKP5	ATS6_HUMAN	51.208	869	403	11	127	2697	258	1117	0	909	Q9UKP5	reviewed	ATS6_HUMAN	A disintegrin and metalloproteinase with thrombospondin motifs 6 (ADAM-TS 6) (ADAM-TS6) (ADAMTS-6) (EC 3.4.24.-)	ADAMTS6	Homo sapiens (Human)	1117	GO:0001822; GO:0003279; GO:0004222; GO:0005576; GO:0006508; GO:0008237; GO:0030198; GO:0031012; GO:0035904; GO:0046872; GO:0060976
g11906	266.3242735	-0.795379564	0.26472268	-3.004576575	0.002659508	0.010537708	176	226	193	96	128	176	521	365	407	308	503	337	sp	Q99497	PARK7_HUMAN	63.388	183	67	0	7	555	6	188	9.90E-76	228	Q99497	reviewed	PARK7_HUMAN	"Parkinson disease protein 7 (Maillard deglycase) (Oncogene DJ1) (Parkinsonism-associated deglycase) (Protein DJ-1) (DJ-1) (Protein/nucleic acid deglycase DJ-1) (EC 3.1.2.-, EC 3.5.1.-, EC 3.5.1.124)"	PARK7	Homo sapiens (Human)	189	GO:0000785; GO:0001933; GO:0002866; GO:0003713; GO:0003729; GO:0005102; GO:0005507; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005758; GO:0005759; GO:0005783; GO:0005829; GO:0005886; GO:0005912; GO:0006281; GO:0006469; GO:0006508; GO:0006517; GO:0006914; GO:0006954; GO:0006979; GO:0007005; GO:0007265; GO:0007338; GO:0008233; GO:0008344; GO:0009438; GO:0010273; GO:0010628; GO:0010629; GO:0016532; GO:0016605; GO:0016684; GO:0019249; GO:0019826; GO:0019899; GO:0019900; GO:0019955; GO:0030073; GO:0030424; GO:0031334; GO:0031397; GO:0032091; GO:0032148; GO:0032435; GO:0032757; GO:0033138; GO:0033234; GO:0033864; GO:0034599; GO:0036470; GO:0036471; GO:0036478; GO:0036524; GO:0036526; GO:0036527; GO:0036528; GO:0036529; GO:0036530; GO:0036531; GO:0042593; GO:0042743; GO:0042802; GO:0042803; GO:0043523; GO:0043524; GO:0044297; GO:0044388; GO:0044390; GO:0044877; GO:0045121; GO:0045296; GO:0045340; GO:0045944; GO:0046295; GO:0046826; GO:0048471; GO:0050681; GO:0050727; GO:0050787; GO:0050821; GO:0051091; GO:0051444; GO:0051583; GO:0051881; GO:0051897; GO:0051899; GO:0051920; GO:0060081; GO:0060765; GO:0061691; GO:0061727; GO:0070062; GO:0070301; GO:0070994; GO:0097110; GO:0098793; GO:0106044; GO:0106045; GO:0106046; GO:0110095; GO:0140041; GO:0140297; GO:1900182; GO:1901671; GO:1901984; GO:1902176; GO:1902177; GO:1902236; GO:1902903; GO:1902958; GO:1903073; GO:1903094; GO:1903122; GO:1903135; GO:1903136; GO:1903168; GO:1903178; GO:1903181; GO:1903189; GO:1903197; GO:1903200; GO:1903376; GO:1903377; GO:1903384; GO:1903427; GO:1903428; GO:1903599; GO:1903751; GO:1905259; GO:1990381; GO:1990422; GO:2000157; GO:2000379; GO:2000679; GO:2000825; GO:2001237; GO:2001268
g9401	191.9693251	0.58220303	0.223061801	2.610052586	0.009052831	0.028773699	206	197	307	189	90	223	208	216	154	192	184	161	sp	O76031	CLPX_HUMAN	64.062	128	46	0	1	384	487	614	1.47E-45	159	O76031	reviewed	CLPX_HUMAN	"ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial"	CLPX	Homo sapiens (Human)	633	GO:0005524; GO:0005654; GO:0005739; GO:0005743; GO:0005759; GO:0005829; GO:0006508; GO:0008270; GO:0009368; GO:0009841; GO:0016504; GO:0016887; GO:0042645; GO:0046034; GO:0046983; GO:0051082; GO:0051603; GO:0140662
g21415	2767.157152	-1.285084914	0.357890713	-3.59071881	0.000329767	0.00179346	2069	571	794	908	1430	2228	5061	4061	3437	6253	4828	4406	sp	Q9UQC9	CLCA2_HUMAN	34.615	104	63	2	55	366	741	839	7.70E-13	70.1	Q9UQC9	reviewed	CLCA2_HUMAN	"Calcium-activated chloride channel regulator 2 (EC 3.4.-.-) (Calcium-activated chloride channel family member 2) (hCLCA2) (Calcium-activated chloride channel protein 3) (CaCC-3) (hCaCC-3) [Cleaved into: Calcium-activated chloride channel regulator 2, 109 kDa form; Calcium-activated chloride channel regulator 2, 35 kDa form]"	CLCA2 CACC3	Homo sapiens (Human)	943	GO:0004222; GO:0005229; GO:0005254; GO:0005576; GO:0005654; GO:0005829; GO:0005886; GO:0006508; GO:0007155; GO:0009925; GO:0030054; GO:0031965; GO:0034220; GO:0046872; GO:0070161
g21414	7515.648886	-1.369149273	0.381147946	-3.592172773	0.000327932	0.001785168	4973	1287	2565	1893	3972	5986	14282	10769	9425	16701	14321	11912	sp	P54281	CLCA1_BOVIN	30.906	618	378	13	124	1941	22	602	8.31E-84	285	P54281	reviewed	CLCA1_BOVIN	Calcium-activated chloride channel regulator 1 (EC 3.4.-.-) (Calcium-activated chloride channel) (Epithelial chloride channel protein)		Bos taurus (Bovine)	903	GO:0005229; GO:0005886; GO:0006508; GO:0006816; GO:0008237; GO:0016324; GO:0046872
g3728	1310.592715	-1.419914758	0.348785126	-4.071030132	4.68E-05	0.000334282	396	731	1120	375	209	952	2777	2214	2065	2493	2230	2102	sp	Q6GQ29	CBPQ_XENLA	58.862	457	188	0	91	1461	13	469	0	567	Q6GQ29	reviewed	CBPQ_XENLA	Carboxypeptidase Q (EC 3.4.17.-) (Plasma glutamate carboxypeptidase)	cpq pgcp	Xenopus laevis (African clawed frog)	469	GO:0004180; GO:0005615; GO:0005737; GO:0005764; GO:0005783; GO:0005794; GO:0006508; GO:0042803; GO:0043171; GO:0046872; GO:0070573
g5188	210.1213384	-2.036749014	0.422824779	-4.817004855	1.46E-06	1.63E-05	70	123	67	102	31	42	522	497	434	110	369	501	sp	Q4R7U8	ASGL1_MACFA	46.602	309	155	3	7	933	1	299	9.44E-86	263	Q4R7U8	reviewed	ASGL1_MACFA	Isoaspartyl peptidase/L-asparaginase (EC 3.4.19.5) (EC 3.5.1.1) (Asparaginase-like protein 1) (Beta-aspartyl-peptidase) (Isoaspartyl dipeptidase) (L-asparagine amidohydrolase) [Cleaved into: Isoaspartyl peptidase/L-asparaginase alpha chain; Isoaspartyl peptidase/L-asparaginase beta chain]	ASRGL1 QtsA-14329	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	308	GO:0001917; GO:0004067; GO:0005737; GO:0006508; GO:0008798; GO:0033345
g19533	13.68848852	5.601881772	1.656682667	3.381384911	0.000721214	0.003486307	106	11	30	0	9	4	0	0	0	4	0	0	sp	Q9Y5R2	MMP24_HUMAN	35.34	515	277	20	127	1581	81	569	2.41E-65	228	Q9Y5R2	reviewed	MMP24_HUMAN	Matrix metalloproteinase-24 (MMP-24) (EC 3.4.24.-) (Membrane-type matrix metalloproteinase 5) (MT-MMP 5) (MTMMP5) (Membrane-type-5 matrix metalloproteinase) (MT5-MMP) (MT5MMP) [Cleaved into: Processed matrix metalloproteinase-24]	MMP24 MT5MMP	Homo sapiens (Human)	645	GO:0004222; GO:0005615; GO:0005886; GO:0006508; GO:0008047; GO:0008270; GO:0010001; GO:0030198; GO:0030574; GO:0031012; GO:0032588; GO:0044331; GO:0045296; GO:0050965; GO:0070062; GO:0097150; GO:0098742
g8151	80.06974616	-1.171206117	0.42080143	-2.783275039	0.005381317	0.018868511	25	85	68	61	15	15	168	144	118	175	106	102	sp	Q4R684	AMZ2_MACFA	32.273	220	140	4	346	990	98	313	6.33E-25	107	Q4R684	reviewed	AMZ2_MACFA	Archaemetzincin-2 (EC 3.4.-.-) (Archeobacterial metalloproteinase-like protein 2)	AMZ2 QtsA-18820	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	360	GO:0006508; GO:0008237; GO:0046872
g1331	137.6802664	-0.80310447	0.310061286	-2.590147513	0.009593481	0.030178646	89	113	119	122	32	57	197	153	216	295	236	166	sp	Q8BHG1	NRDC_MOUSE	52.89	571	243	3	385	2019	222	792	0	645	Q8BHG1	reviewed	NRDC_MOUSE	Nardilysin (EC 3.4.24.61) (N-arginine dibasic convertase) (NRD convertase) (NRD-C) (Nardilysin convertase)	Nrdc Nrd1	Mus musculus (Mouse)	1161	GO:0004222; GO:0005739; GO:0006508; GO:0008233; GO:0030425; GO:0031643; GO:0046872; GO:0050772; GO:0051044; GO:0120163
g16353	269.4491747	-1.281413592	0.301236395	-4.253847181	2.10E-05	0.000168709	137	157	241	162	46	107	741	529	280	555	269	492	sp	A3KG59	P20D2_MOUSE	42.172	396	183	9	13	1167	26	386	2.43E-79	254	A3KG59	reviewed	P20D2_MOUSE	Xaa-Arg dipeptidase (EC 3.4.13.4)	Pm20d2 Acy1l2 Gm424	Mus musculus (Mouse)	431	GO:0004180; GO:0005654; GO:0006508; GO:0016805; GO:0042802; GO:0051246
g20362	74.57773436	-2.929125029	0.889953647	-3.291323138	0.000997173	0.004606155	27	12	6	0	18	9	138	66	53	77	559	23	sp	O57382	TLL2_XENLA	28.475	295	128	5	40	678	595	888	3.20E-34	132	O57382	reviewed	TLL2_XENLA	Tolloid-like protein 2 (EC 3.4.24.-) (Metalloprotease xolloid) (Xenopus tolloid)	tll2 xld	Xenopus laevis (African clawed frog)	1019	GO:0004222; GO:0005509; GO:0005576; GO:0006508; GO:0008270; GO:0030154
g19379	110.0660659	6.539549416	1.114606487	5.867137411	4.43E-09	9.22E-08	198	164	57	130	357	35	0	5	0	0	0	11	sp	P20918	PLMN_MOUSE	40.206	291	147	7	817	1677	545	812	1.68E-55	203	P20918	reviewed	PLMN_MOUSE	"Plasminogen (EC 3.4.21.7) [Cleaved into: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B]"	Plg	Mus musculus (Mouse)	812	GO:0002020; GO:0004175; GO:0004252; GO:0005102; GO:0005576; GO:0005615; GO:0006508; GO:0007596; GO:0009897; GO:0009986; GO:0010812; GO:0016525; GO:0019899; GO:0019900; GO:0019904; GO:0022617; GO:0034185; GO:0042246; GO:0042730; GO:0043536; GO:0045445; GO:0046716; GO:0048771; GO:0051087; GO:0051603; GO:0051702; GO:0051918; GO:0051919; GO:0060707; GO:0060716; GO:0062023; GO:0071674; GO:0098685; GO:0098978; GO:0099183; GO:1990405
g17596	686.4856293	0.833291583	0.326806434	2.549801642	0.010778422	0.033076823	870	584	554	557	1033	561	721	551	524	611	449	653	sp	B1AQJ2	UBP36_MOUSE	48.156	461	229	6	67	1440	12	465	2.44E-136	451	B1AQJ2	reviewed	UBP36_MOUSE	Ubiquitin carboxyl-terminal hydrolase 36 (EC 2.3.2.-) (EC 3.4.19.12) (Deubiquitinating enzyme 36) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36)	Usp36 Kiaa1453	Mus musculus (Mouse)	1098	GO:0003723; GO:0004843; GO:0005634; GO:0005730; GO:0005737; GO:0005829; GO:0006325; GO:0006508; GO:0007000; GO:0016242; GO:0016579; GO:0016607; GO:0016740; GO:0031647; GO:0042981; GO:0050821; GO:0140936; GO:1990380; GO:2000232
g14832	40.86494678	-1.739142665	0.694370169	-2.504633326	0.01225784	0.036805502	20	41	13	16	10	0	58	49	55	141	114	35	sp	Q5G266	NETR_TRAPH	31.173	324	197	7	157	1128	194	491	8.63E-38	149	Q5G266	reviewed	NETR_TRAPH	Neurotrypsin (EC 3.4.21.-) (Serine protease 12)	PRSS12	Trachypithecus phayrei (Phayre's leaf monkey)	875	GO:0004252; GO:0005886; GO:0006508; GO:0006887; GO:0030424; GO:0030425; GO:0043083; GO:0043195
g23767	87.8515845	-1.813971844	0.633340281	-2.864134648	0.004181502	0.015314406	11	41	104	25	7	33	250	249	48	332	54	106	sp	Q2T9J0	TYSD1_HUMAN	32.67	603	331	17	97	1866	26	566	9.54E-81	268	Q2T9J0	reviewed	TYSD1_HUMAN	"Peroxisomal leader peptide-processing protease (EC 3.4.21.-) (Trypsin domain-containing protein 1) [Cleaved into: Peroxisomal leader peptide-processing protease, 15 kDa form; Peroxisomal leader peptide-processing protease, 45 kDa form]"	TYSND1	Homo sapiens (Human)	566	GO:0002020; GO:0004252; GO:0005777; GO:0005782; GO:0005829; GO:0006508; GO:0016020; GO:0016485; GO:0031998; GO:0042802
g11276	48676.39751	8.097119115	0.826452623	9.797438941	1.15E-22	2.17E-20	84772	23520	42462	642	98361	192556	620	338	148	97	507	550	sp	Q8TE57	ATS16_HUMAN	31.452	744	413	25	1	2085	292	987	1.31E-93	318	Q8TE57	reviewed	ATS16_HUMAN	A disintegrin and metalloproteinase with thrombospondin motifs 16 (ADAM-TS 16) (ADAM-TS16) (ADAMTS-16) (EC 3.4.24.-)	ADAMTS16 KIAA2029	Homo sapiens (Human)	1224	GO:0001658; GO:0003073; GO:0004222; GO:0005576; GO:0006508; GO:0030198; GO:0031012; GO:0046872; GO:0048232; GO:1902017
g11277	15892.98723	8.255730851	0.819944541	10.06864543	7.60E-24	1.80E-21	28686	8547	13491	240	31993	61959	155	106	53	24	138	183	sp	P25723	TLD_DROME	26.667	210	134	7	118	711	388	589	1.18E-14	76.6	P25723	reviewed	TLD_DROME	Dorsal-ventral patterning protein tolloid (EC 3.4.24.-)	tld CG6868	Drosophila melanogaster (Fruit fly)	1067	GO:0004222; GO:0005509; GO:0005518; GO:0005615; GO:0006508; GO:0007313; GO:0007378; GO:0008270; GO:0008586; GO:0009953; GO:0016485; GO:0030513; GO:0032927; GO:0045464
g11275	12727.90389	8.126767321	0.819272646	9.919490609	3.42E-23	7.10E-21	20229	6253	12362	204	23139	54671	175	95	42	25	110	132	sp	Q8TE57	ATS16_HUMAN	36.17	94	57	2	223	495	87	180	1.11E-08	58.2	Q8TE57	reviewed	ATS16_HUMAN	A disintegrin and metalloproteinase with thrombospondin motifs 16 (ADAM-TS 16) (ADAM-TS16) (ADAMTS-16) (EC 3.4.24.-)	ADAMTS16 KIAA2029	Homo sapiens (Human)	1224	GO:0001658; GO:0003073; GO:0004222; GO:0005576; GO:0006508; GO:0030198; GO:0031012; GO:0046872; GO:0048232; GO:1902017
g16700	1823.125097	-2.715117451	0.54078377	-5.02070809	5.15E-07	6.47E-06	900	101	296	269	544	143	3769	2607	2511	2837	4716	6095	sp	Q9R0S2	MMP24_MOUSE	33.012	518	292	17	124	1599	56	544	9.63E-68	233	Q9R0S2	reviewed	MMP24_MOUSE	Matrix metalloproteinase-24 (MMP-24) (EC 3.4.24.-) (Matrix metalloproteinase-21) (MMP-21) (Membrane-type matrix metalloproteinase 5) (MT-MMP 5) (MTMMP5) (Membrane-type-5 matrix metalloproteinase) (MT5-MMP) (MT5MMP) [Cleaved into: Processed matrix metalloproteinase-24]	Mmp24 Mmp21 Mt5mmp	Mus musculus (Mouse)	618	GO:0004222; GO:0005615; GO:0005886; GO:0006508; GO:0008270; GO:0010001; GO:0030198; GO:0030574; GO:0031012; GO:0032588; GO:0044331; GO:0045296; GO:0050965; GO:0097150; GO:0098742
g7450	11690.72658	3.994041884	0.797530572	5.00801101	5.50E-07	6.86E-06	45479	4626	2011	12639	6304	42963	2706	5110	1409	1028	1253	159	sp	Q15485	FCN2_HUMAN	57.277	213	89	2	433	1068	102	313	3.09E-79	248	Q15485	reviewed	FCN2_HUMAN	Ficolin-2 (37 kDa elastin-binding protein) (Collagen/fibrinogen domain-containing protein 2) (EBP-37) (Ficolin-B) (Ficolin-beta) (Hucolin) (L-ficolin) (Serum lectin p35)	FCN2 FCNL	Homo sapiens (Human)	313	GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005576; GO:0005581; GO:0005615; GO:0006508; GO:0008228; GO:0009897; GO:0043394; GO:0043654; GO:0046872; GO:0048306; GO:0050829; GO:0050830; GO:0062023; GO:0070062; GO:0072562; GO:0097367; GO:1903028; GO:1905370; GO:2001065
g14701	901.5490025	-1.157128579	0.387768011	-2.984074363	0.002844376	0.011138753	531	642	525	698	200	270	1544	1876	2671	1246	465	1292	sp	P80912	HINT1_RABIT	61.538	130	46	1	1	390	1	126	2.48E-54	169	P80912	reviewed	HINT1_RABIT	Adenosine 5'-monophosphoramidase HINT1 (EC 3.9.1.-) (Desumoylating isopeptidase HINT1) (EC 3.4.22.-) (Histidine triad nucleotide-binding protein 1) (P13.7)	HINT1 HINT	Oryctolagus cuniculus (Rabbit)	126	GO:0000118; GO:0000166; GO:0005634; GO:0005737; GO:0006355; GO:0006508; GO:0009154; GO:0016787; GO:0016926; GO:0016929; GO:0043530; GO:0072332
g9583	860.9489486	1.12855237	0.415716881	2.714713837	0.006633306	0.022337911	994	777	830	2445	591	427	1125	623	486	554	734	391	sp	Q9NVE5	UBP40_HUMAN	52.143	420	186	6	1	1248	1	409	3.57E-110	381	Q9NVE5	reviewed	UBP40_HUMAN	Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.4.19.12) (Deubiquitinating enzyme 40) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40)	USP40	Homo sapiens (Human)	1235	GO:0004843; GO:0005634; GO:0005829; GO:0006508; GO:0016579
g11751	20951.15958	4.074077154	1.142767467	3.565097251	0.000363721	0.001949257	1560	18770	61533	125	1090	121843	177	1152	5348	870	4565	2580	sp	P49275	DERF3_DERFA	38.258	264	141	9	1	759	4	256	4.07E-43	150	P49275	reviewed	DERF3_DERFA	Mite allergen Der f 3 (EC 3.4.21.-) (Allergen Der f III) (allergen Der f 3)	DERF3	Dermatophagoides farinae (American house dust mite)	259	GO:0004252; GO:0005576; GO:0006508
g11752	18553.96931	4.730744155	1.150949762	4.11029596	3.95E-05	0.000289521	1484	18447	71466	122	747	96575	110	600	3473	566	2739	1236	sp	P70059	TRY2_XENLA	40.769	260	130	9	1	768	1	240	3.17E-52	173	P70059	reviewed	TRY2_XENLA	Trypsin (EC 3.4.21.4)		Xenopus laevis (African clawed frog)	244	GO:0004252; GO:0005576; GO:0006508; GO:0007586; GO:0046872
g4774	8421.655995	4.337543391	1.159608061	3.740525386	0.000183636	0.001089696	346	5341	32860	66	267	45382	102	447	1880	309	1362	1032	sp	Q6P8K8	CBPA4_MOUSE	36.765	408	230	10	61	1260	21	408	2.75E-77	249	Q6P8K8	reviewed	CBPA4_MOUSE	Carboxypeptidase A4 (EC 3.4.17.-)	Cpa4	Mus musculus (Mouse)	420	GO:0004181; GO:0005615; GO:0006508; GO:0008270; GO:0042447; GO:0043171
g19541	5551.652022	3.996099525	0.575380217	6.945145847	3.78E-12	1.47E-10	12536	4402	3601	1620	15936	7807	627	381	599	545	1524	834	sp	Q9ULZ9	MMP17_HUMAN	37.037	486	289	8	103	1536	47	523	1.07E-92	298	Q9ULZ9	reviewed	MMP17_HUMAN	Matrix metalloproteinase-17 (MMP-17) (EC 3.4.24.-) (Membrane-type matrix metalloproteinase 4) (MT-MMP 4) (MTMMP4) (Membrane-type-4 matrix metalloproteinase) (MT4-MMP) (MT4MMP)	MMP17 MT4MMP	Homo sapiens (Human)	603	GO:0001822; GO:0004222; GO:0005615; GO:0005886; GO:0006508; GO:0008047; GO:0008270; GO:0030198; GO:0030574; GO:0031012; GO:0042756; GO:0070006; GO:0098552
g19543	4.709831446	5.897589516	2.176540764	2.709615925	0.006736116	0.022617941	11	19	8	0	10	0	0	0	0	0	0	0	sp	Q99542	MMP19_HUMAN	36	250	146	7	1	729	230	472	2.07E-40	149	Q99542	reviewed	MMP19_HUMAN	Matrix metalloproteinase-19 (MMP-19) (EC 3.4.24.-) (Matrix metalloproteinase RASI) (Matrix metalloproteinase-18) (MMP-18)	MMP19 MMP18 RASI	Homo sapiens (Human)	508	GO:0001525; GO:0004222; GO:0004252; GO:0005576; GO:0005615; GO:0006508; GO:0008270; GO:0022617; GO:0030154; GO:0030198; GO:0030574; GO:0031012
g11953	297.3882082	-1.131130058	0.23557675	-4.801535197	1.57E-06	1.74E-05	212	200	134	225	73	137	656	589	435	587	340	407	sp	A0A0R4IB93	UBP48_DANRE	51.579	760	332	7	1	2232	1	740	0	789	A0A0R4IB93	reviewed	UBP48_DANRE	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.4.19.12) (Ubiquitin specific peptidase 48)	usp48	Danio rerio (Zebrafish) (Brachydanio rerio)	1047	GO:0004197; GO:0004843; GO:0005634; GO:0005829; GO:0006508; GO:0016579; GO:1904888
g11952	140.4312821	-1.241864514	0.292255843	-4.249237592	2.14E-05	0.000171739	79	86	130	74	37	42	250	336	163	246	239	190	sp	Q86UV5	UBP48_HUMAN	43.446	267	127	8	4	750	774	1034	1.74E-44	163	Q86UV5	reviewed	UBP48_HUMAN	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.4.19.12) (Deubiquitinating enzyme 48) (Ubiquitin thioesterase 48) (Ubiquitin-specific peptidase 48) (Ubiquitin-specific protease 48) (Ubiquitin-specific-processing protease 48)	USP48 USP31	Homo sapiens (Human)	1035	GO:0004197; GO:0004843; GO:0005634; GO:0005654; GO:0005739; GO:0005829; GO:0005929; GO:0006508; GO:0016579; GO:0101005
g11951	629.5924367	4.826038076	1.318521044	3.660190406	0.000252028	0.001426395	53	652	2933	4	25	2851	0	28	189	4	25	61	sp	P07478	TRY2_HUMAN	45.175	228	113	3	64	747	24	239	7.40E-63	200	P07478	reviewed	TRY2_HUMAN	Trypsin-2 (EC 3.4.21.4) (Anionic trypsinogen) (Serine protease 2) (Trypsin II)	PRSS2 TRY2 TRYP2	Homo sapiens (Human)	247	GO:0004222; GO:0004252; GO:0005509; GO:0005576; GO:0005615; GO:0006508; GO:0007586; GO:0008236; GO:0019730; GO:0022617; GO:0030307; GO:0030574; GO:0031012; GO:0035578; GO:0045785
g11950	3083.121072	4.916997213	1.194187601	4.117441186	3.83E-05	0.000282491	198	4049	16499	38	75	11650	6	213	1091	125	136	58	sp	Q8NHM4	TRY6_HUMAN	44.13	247	118	7	25	756	13	242	1.95E-52	174	Q8NHM4	reviewed	TRY6_HUMAN	Putative trypsin-6 (EC 3.4.21.4) (Serine protease 3 pseudogene 2) (Trypsinogen C)	PRSS3P2 T6 TRY6	Homo sapiens (Human)	247	GO:0004252; GO:0005615; GO:0006508; GO:0043542; GO:0046872
g11955	595.2236394	4.046882884	1.468849604	2.755137675	0.005866744	0.020217956	26	269	2193	0	11	3346	0	38	250	29	77	54	sp	P39675	DERP3_DERPT	39.516	248	133	6	64	792	25	260	1.45E-47	162	P39675	reviewed	DERP3_DERPT	Mite allergen Der p 3 (EC 3.4.21.-) (Allergen Der p III) (allergen Der p 3)	DERP3	Dermatophagoides pteronyssinus (European house dust mite)	261	GO:0004252; GO:0005576; GO:0006508
g11954	901.2395204	4.246071535	1.15183605	3.686350617	0.000227493	0.001306381	122	826	2539	10	8	5379	15	71	213	27	180	57	sp	Q07943	VDP_BOMMO	35.032	157	88	3	142	606	105	249	1.19E-26	105	Q07943	reviewed	VDP_BOMMO	Vitellin-degrading protease (EC 3.4.21.-) [Cleaved into: Beta-VTN protease; Alpha-VTN protease chain 1; Alpha-VTN protease chain 2]		Bombyx mori (Silk moth)	264	GO:0004252; GO:0006508
g5273	217.7233766	-1.319085867	0.326997748	-4.033929514	5.49E-05	0.000380873	137	251	177	44	34	93	569	415	272	433	282	299	sp	B2RYG6	OTUB1_RAT	62.302	252	94	1	55	807	19	270	3.59E-107	314	B2RYG6	reviewed	OTUB1_RAT	Ubiquitin thioesterase OTUB1 (EC 3.4.19.12) (Deubiquitinating enzyme OTUB1) (OTU domain-containing ubiquitin aldehyde-binding protein 1) (Otubain-1) (Ubiquitin-specific-processing protease OTUB1)	Otub1	Rattus norvegicus (Rat)	271	GO:0002250; GO:0004843; GO:0005737; GO:0006281; GO:0006508; GO:0006974; GO:0016579; GO:0019784; GO:0031625; GO:0043130; GO:0055105; GO:0071108; GO:0071347; GO:1904263; GO:2000780
g7821	33.74957044	-2.632976067	0.892320835	-2.950705579	0.00317049	0.012167406	7	25	0	17	2	0	75	40	85	69	103	43	sp	P0C872	JMJD7_MOUSE	27.451	306	169	10	313	1191	28	293	4.11E-30	121	P0C872	reviewed	JMJD7_MOUSE	Bifunctional peptidase and (3S)-lysyl hydroxylase Jmjd7 (EC 1.14.11.63) (EC 3.4.-.-) (JmjC domain-containing protein 7) (Jumonji domain-containing protein 7) (L-lysine (3S)-hydroxylase Jmjd7)	Jmjd7	Mus musculus (Mouse)	316	GO:0004175; GO:0004177; GO:0004497; GO:0005634; GO:0005737; GO:0006508; GO:0016706; GO:0035064; GO:0046872; GO:0106155
g1360	167.9180628	-1.467003662	0.324018864	-4.527525481	5.97E-06	5.65E-05	114	102	150	41	32	64	447	315	164	384	321	189	sp	B6MUN4	MYSM1_BRAFL	44.504	373	156	6	1834	2937	438	764	4.45E-91	311	B6MUN4	reviewed	MYSM1_BRAFL	"Histone H2A deubiquitinase MYSM1 (2A-DUB) (EC 3.4.19.-) (Myb-like, SWIRM and MPN domain-containing protein 1)"	MYSM1 BRAFLDRAFT_86936	Branchiostoma floridae (Florida lancelet) (Amphioxus)	809	GO:0003677; GO:0003713; GO:0005634; GO:0006338; GO:0006508; GO:0042393; GO:0045944; GO:0046872; GO:0140492; GO:0140950
g20679	361.5560455	-1.568122636	0.229266781	-6.839728927	7.93E-12	2.93E-10	161	219	237	98	70	188	1036	731	511	702	506	548	sp	P13676	ACPH_RAT	48.333	720	354	11	52	2175	13	726	0	629	P13676	reviewed	ACPH_RAT	Acylamino-acid-releasing enzyme (AARE) (EC 3.4.19.1) (Acyl-peptide hydrolase) (APH) (Acylaminoacyl-peptidase)	Apeh	Rattus norvegicus (Rat)	732	GO:0004252; GO:0005737; GO:0006508; GO:0008242; GO:0042802; GO:0050435
g3140	1068.943345	0.881884391	0.203575609	4.331974715	1.48E-05	0.00012474	1864	1169	1559	855	700	1142	1548	1130	806	917	478	811	sp	P10619	PPGB_HUMAN	43.167	461	232	7	139	1458	29	480	1.46E-128	385	P10619	reviewed	PPGB_HUMAN	Lysosomal protective protein (EC 3.4.16.5) (Carboxypeptidase C) (Carboxypeptidase L) (Cathepsin A) (Protective protein cathepsin A) (PPCA) (Protective protein for beta-galactosidase) [Cleaved into: Lysosomal protective protein 32 kDa chain; Lysosomal protective protein 20 kDa chain]	CTSA PPGB	Homo sapiens (Human)	480	GO:0004180; GO:0004185; GO:0005576; GO:0005764; GO:0005783; GO:0006508; GO:0006886; GO:0008047; GO:0016020; GO:0031647; GO:0035578; GO:0043202; GO:0043231; GO:0070062; GO:1904714; GO:1904715
g17411	1281.054384	0.951742943	0.330625463	2.878613562	0.003994274	0.014732266	880	2212	1883	976	950	1733	1757	966	573	1712	664	966	sp	Q70CQ4	UBP31_HUMAN	40.026	767	358	16	733	2880	126	841	1.46E-169	535	Q70CQ4	reviewed	UBP31_HUMAN	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.4.19.12) (Deubiquitinating enzyme 31) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31)	USP31 KIAA1203	Homo sapiens (Human)	1352	GO:0004843; GO:0005634; GO:0006508; GO:0016579
g22762	793.6411153	1.830469276	0.558922747	3.274995132	0.001056638	0.004843251	2122	1070	799	143	1110	959	616	470	625	513	84	348	sp	A0A182C2Z2	OVCH_HALRO	35	340	186	13	2041	2979	545	876	1.04E-41	171	A0A182C2Z2	reviewed	OVCH_HALRO	Ovochymase (HrOVCH) (EC 3.4.21.-)	OVCH	Halocynthia roretzi (Sea squirt) (Cynthia roretzi)	1575	GO:0004252; GO:0005576; GO:0006508; GO:0007340; GO:0009566; GO:0048477
g23544	122.3508877	3.402315636	1.350820078	2.518703779	0.01177877	0.035614842	275	225	33	27	98	480	120	0	3	66	0	0	sp	Q8R4K8	PAPP1_MOUSE	35.924	1055	565	33	1468	4470	620	1617	0	605	Q8R4K8	reviewed	PAPP1_MOUSE	Pappalysin-1 (EC 3.4.24.79) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase) (Pregnancy-associated plasma protein A) (PAPP-A)	Pappa	Mus musculus (Mouse)	1624	GO:0004175; GO:0004222; GO:0005615; GO:0006508; GO:0007166; GO:0007565; GO:0030163; GO:0032354; GO:0046872; GO:0071548
g21781	1339.474909	1.490816282	0.28616542	5.209631136	1.89E-07	2.67E-06	2248	3163	1732	743	1252	1271	1229	648	886	887	689	795	sp	Q6TH47	STBPA_DANRE	51.282	195	91	3	829	1413	228	418	3.09E-66	221	Q6TH47	reviewed	STBPA_DANRE	STAM-binding protein-like A (EC 3.4.19.-)	stambpa amsh stambp	Danio rerio (Zebrafish) (Brachydanio rerio)	418	GO:0005768; GO:0006508; GO:0032154; GO:0046872; GO:0061578; GO:0070536; GO:0140492
g24095	39.60260774	-3.554049649	1.047512112	-3.392848262	0.000691699	0.003365309	18	23	65	0	0	0	102	64	36	65	116	67	sp	Q1EHB3	ATS7_RAT	34.122	296	171	10	169	1026	229	510	2.65E-43	165	Q1EHB3	reviewed	ATS7_RAT	A disintegrin and metalloproteinase with thrombospondin motifs 7 (ADAM-TS 7) (ADAM-TS7) (ADAMTS-7) (EC 3.4.24.-) (COMPase)	Adamts7	Rattus norvegicus (Rat)	1595	GO:0001503; GO:0002062; GO:0004222; GO:0005576; GO:0006029; GO:0006508; GO:0008237; GO:0009986; GO:0030198; GO:0030199; GO:0031012; GO:0032331; GO:0043931; GO:0046872; GO:0051603; GO:0071347; GO:0071356; GO:0071773
g15116	343.2363649	3.052202393	0.946582721	3.224443384	0.001262178	0.005651808	135	424	1239	17	8	1471	112	27	133	34	66	156	sp	O57579	AMPN_CHICK	40.603	431	214	8	1	1206	550	967	5.11E-102	327	O57579	reviewed	AMPN_CHICK	Aminopeptidase Ey (EC 3.4.11.20) (Aminopeptidase N)	ANPEP APDE	Gallus gallus (Chicken)	972	GO:0005615; GO:0005737; GO:0005886; GO:0006508; GO:0008270; GO:0042277; GO:0043171; GO:0070006
g15115	321.4210744	3.04104331	0.93598934	3.249014899	0.001158054	0.005255267	194	415	1213	41	12	1239	71	26	179	12	31	166	sp	P15145	AMPN_PIG	46.889	450	219	6	460	1791	71	506	2.66E-129	406	P15145	reviewed	AMPN_PIG	Aminopeptidase N (AP-N) (pAPN) (EC 3.4.11.2) (Alanyl aminopeptidase) (Aminopeptidase M) (AP-M) (Microsomal aminopeptidase) (gp130) (CD antigen CD13)	ANPEP	Sus scrofa (Pig)	963	GO:0001525; GO:0001618; GO:0005615; GO:0005737; GO:0005886; GO:0006508; GO:0008270; GO:0030154; GO:0042277; GO:0043171; GO:0070006
g19176	2635.5521	4.537140326	1.116025931	4.065443465	4.79E-05	0.00034056	218	1949	6377	19	164	17052	19	96	454	120	382	231	sp	P00730	CBPA1_BOVIN	35.865	237	146	4	16	717	22	255	3.50E-42	152	P00730	reviewed	CBPA1_BOVIN	Carboxypeptidase A1 (EC 3.4.17.1)	CPA1 CPA	Bos taurus (Bovine)	419	GO:0004181; GO:0005615; GO:0006508; GO:0006691; GO:0008270
g22787	276.0163014	-4.920507087	1.017786931	-4.834515888	1.33E-06	1.50E-05	35	74	12	8	0	8	1002	665	1030	415	0	814	sp	Q8NF86	PRS33_HUMAN	33.333	267	143	11	364	1128	31	274	1.71E-30	123	Q8NF86	reviewed	PRS33_HUMAN	Serine protease 33 (EC 3.4.21.-) (Serine protease EOS)	PRSS33	Homo sapiens (Human)	280	GO:0004252; GO:0005615; GO:0005737; GO:0006508; GO:0070528
g21548	280.4095566	-0.844762115	0.353864441	-2.387247815	0.016975044	0.047793707	303	314	199	68	121	92	497	383	298	521	371	526	sp	P78509	RELN_HUMAN	42.433	3502	1778	62	94	10179	31	3434	0	2785	P78509	reviewed	RELN_HUMAN	Reelin (EC 3.4.21.-)	RELN	Homo sapiens (Human)	3460	GO:0000902; GO:0001764; GO:0001934; GO:0005576; GO:0005615; GO:0005737; GO:0005886; GO:0006508; GO:0007155; GO:0007411; GO:0007417; GO:0007420; GO:0007616; GO:0007626; GO:0008236; GO:0008306; GO:0010001; GO:0010468; GO:0010976; GO:0016358; GO:0018108; GO:0021511; GO:0021517; GO:0021766; GO:0021800; GO:0021819; GO:0030425; GO:0031012; GO:0032008; GO:0035418; GO:0038026; GO:0043005; GO:0045664; GO:0045860; GO:0046872; GO:0048018; GO:0048265; GO:0050731; GO:0050795; GO:0050804; GO:0051057; GO:0051897; GO:0051968; GO:0060025; GO:0060291; GO:0061003; GO:0070325; GO:0070326; GO:0090129; GO:0097107; GO:0097114; GO:0097119; GO:0097120; GO:0097477; GO:0110157; GO:1900273; GO:1902078; GO:1904936; GO:2000310; GO:2000463; GO:2001222
g19847	85563.9495	8.419773797	0.935743912	8.997946644	2.30E-19	2.74E-17	153892	14989	57560	854	113118	462346	1071	427	130	83	502	859	sp	O77656	MMP13_BOVIN	42.586	263	125	7	514	1299	24	261	1.44E-49	184	O77656	reviewed	MMP13_BOVIN	Collagenase 3 (EC 3.4.24.-) (Matrix metalloproteinase-13) (MMP-13)	MMP13	Bos taurus (Bovine)	471	GO:0004175; GO:0004222; GO:0005509; GO:0005518; GO:0005615; GO:0006508; GO:0008270; GO:0022617; GO:0030198; GO:0030574; GO:0031012; GO:0060349
g19283	23.58409797	-1.935050468	0.725972959	-2.66545805	0.007688352	0.025188145	11	6	23	12	0	3	39	53	9	67	66	36	sp	Q8I7P9	POL5_DROME	36.719	128	78	2	7	390	455	579	5.51E-18	82.8	Q8I7P9	reviewed	POL5_DROME	Retrovirus-related Pol polyprotein from transposon opus [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	pol	Drosophila melanogaster (Fruit fly)	1003	GO:0003676; GO:0003964; GO:0004519; GO:0005634; GO:0006313; GO:0006508; GO:0008233; GO:0015074; GO:0042575
g23897	622.8358486	2.231332504	0.584017406	3.820660963	0.000133095	0.000827324	1792	1693	1117	513	388	296	133	268	107	358	65	578	sp	Q3SYW2	CO2_BOVIN	30.631	444	261	15	628	1869	32	458	2.03E-48	185	Q3SYW2	reviewed	CO2_BOVIN	Complement C2 (EC 3.4.21.43) (C3/C5 convertase) [Cleaved into: Complement C2b fragment; Complement C2a fragment]	C2	Bos taurus (Bovine)	750	GO:0004252; GO:0005576; GO:0006508; GO:0006956; GO:0006958; GO:0009617; GO:0045087; GO:0046872
g852	17818.50189	2.357965446	0.75553972	3.12090203	0.00180298	0.007611407	37616	2844	4966	16899	39870	33146	2927	5924	10253	1018	10363	3542	sp	P90850	YCF2E_CAEEL	47.465	434	204	13	31	1308	14	431	4.94E-125	373	P90850	reviewed	YCF2E_CAEEL	Uncharacterized peptidase C1-like protein F26E4.3	F26E4.3	Caenorhabditis elegans	452	GO:0005615; GO:0006508; GO:0008234
g21351	3080.631414	0.542809324	0.220139025	2.465756915	0.013672409	0.04019297	4578	2988	5133	3544	1490	1933	4680	2784	3006	2518	3028	2424	sp	P53634	CATC_HUMAN	51.481	439	174	5	52	1257	24	460	1.89E-159	460	P53634	reviewed	CATC_HUMAN	Dipeptidyl peptidase 1 (EC 3.4.14.1) (Cathepsin C) (Cathepsin J) (Dipeptidyl peptidase I) (DPP-I) (DPPI) (Dipeptidyl transferase) [Cleaved into: Dipeptidyl peptidase 1 exclusion domain chain (Dipeptidyl peptidase I exclusion domain chain); Dipeptidyl peptidase 1 heavy chain (Dipeptidyl peptidase I heavy chain); Dipeptidyl peptidase 1 light chain (Dipeptidyl peptidase I light chain)]	CTSC CPPI	Homo sapiens (Human)	463	GO:0001913; GO:0004197; GO:0004252; GO:0005576; GO:0005615; GO:0005654; GO:0005764; GO:0005788; GO:0005813; GO:0006508; GO:0006955; GO:0008234; GO:0008239; GO:0016020; GO:0016505; GO:0019902; GO:0030134; GO:0031404; GO:0031642; GO:0033116; GO:0035578; GO:0042802; GO:0043231; GO:0051087; GO:0051603; GO:0062023; GO:0070062; GO:1903052; GO:1903980; GO:2001235
g4298	24016.88942	4.645286486	1.138349949	4.080719194	4.49E-05	0.000322201	2791	35311	148219	266	547	71586	74	1677	7330	644	1638	1326	sp	P80146	SEPR_THESR	41.47	381	195	9	52	1119	30	407	4.46E-80	254	P80146	reviewed	SEPR_THESR	Extracellular serine proteinase (EC 3.4.21.-)		Thermus sp. (strain Rt41A)	410	GO:0004252; GO:0005615; GO:0006508
g4297	17774.42361	4.107801548	1.133336451	3.624520808	0.000289498	0.001608403	1303	16600	65815	102	958	91683	177	980	3525	788	5197	2450	sp	P80146	SEPR_THESR	40.938	320	168	8	205	1128	98	408	4.13E-50	176	P80146	reviewed	SEPR_THESR	Extracellular serine proteinase (EC 3.4.21.-)		Thermus sp. (strain Rt41A)	410	GO:0004252; GO:0005615; GO:0006508
g4296	5554.008604	4.259357356	1.146881175	3.713861078	0.000204121	0.001191188	463	4873	25529	42	330	25282	26	428	1352	184	1125	490	sp	P80146	SEPR_THESR	39.474	380	200	9	58	1119	33	408	5.03E-55	189	P80146	reviewed	SEPR_THESR	Extracellular serine proteinase (EC 3.4.21.-)		Thermus sp. (strain Rt41A)	410	GO:0004252; GO:0005615; GO:0006508
g22664	477.7752765	0.786138797	0.236227309	3.327891263	0.00087506	0.004105814	735	594	597	609	288	360	502	377	584	300	389	378	sp	P48147	PPCE_HUMAN	68.794	705	203	1	4	2067	4	708	0	1049	P48147	reviewed	PPCE_HUMAN	Prolyl endopeptidase (PE) (EC 3.4.21.26) (Post-proline cleaving enzyme)	PREP PEP	Homo sapiens (Human)	710	GO:0004252; GO:0005634; GO:0005737; GO:0005829; GO:0006508; GO:0008236; GO:0016020; GO:0070012
g11962	259.3519209	-0.709893838	0.260784812	-2.722144104	0.006485985	0.021905905	181	216	212	172	84	166	555	302	308	548	190	499	sp	Q5T2D3	OTUD3_HUMAN	42.773	339	158	7	25	990	8	327	1.17E-85	269	Q5T2D3	reviewed	OTUD3_HUMAN	OTU domain-containing protein 3 (EC 3.4.19.12)	OTUD3 KIAA0459	Homo sapiens (Human)	398	GO:0004843; GO:0005634; GO:0005737; GO:0005829; GO:0006508; GO:0016579; GO:0031669; GO:0035871; GO:0044313; GO:0050821; GO:0051898; GO:0071108; GO:1990167
g14920	10.84119094	-2.696763436	0.967200368	-2.788215892	0.005299921	0.018655636	3	0	8	5	0	0	10	27	17	40	29	10	sp	P0CT40	TF29_SCHPO	34.884	129	82	1	16	396	545	673	7.50E-17	79.3	P0CT40	reviewed	TF29_SCHPO	Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein)	Tf2-9 SPBC9B6.02c	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	1333	GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872
g1886	1211.872337	-2.105324409	0.214072456	-9.834634735	7.99E-23	1.55E-20	405	524	668	308	198	330	4938	1841	2537	2434	1638	1659	sp	Q3UVK0	ERMP1_MOUSE	39.571	839	480	12	187	2697	85	898	0	604	Q3UVK0	reviewed	ERMP1_MOUSE	Endoplasmic reticulum metallopeptidase 1 (EC 3.4.-.-) (Felix-ina)	Ermp1 D19Wsu12e Fxna Kiaa1815	Mus musculus (Mouse)	898	GO:0001541; GO:0005789; GO:0006508; GO:0008235; GO:0030968; GO:0034599; GO:0046872
g1147	483.0475469	1.867885953	0.273778918	6.822606958	8.94E-12	3.24E-10	1479	789	813	450	296	395	420	218	281	202	112	282	sp	Q8C1A5	THOP1_MOUSE	63.262	656	241	0	25	1992	22	677	0	870	Q8C1A5	reviewed	THOP1_MOUSE	Thimet oligopeptidase (EC 3.4.24.15)	Thop1	Mus musculus (Mouse)	687	GO:0004222; GO:0005758; GO:0006508; GO:0006518; GO:0008233; GO:0035556; GO:0042277; GO:0043171; GO:0046872
g2495	166.7728598	7.352985419	1.026094514	7.165992332	7.72E-13	3.40E-11	286	315	217	20	551	71	5	7	0	0	0	4	sp	P55112	NAS4_CAEEL	36.15	213	132	3	157	786	78	289	1.78E-43	153	P55112	reviewed	NAS4_CAEEL	Zinc metalloproteinase nas-4 (EC 3.4.24.-) (Nematode astacin 4)	nas-4 C05D11.6	Caenorhabditis elegans	315	GO:0004222; GO:0005576; GO:0006508; GO:0008270
g2494	3341.230009	-3.024186503	0.646518874	-4.677646123	2.90E-06	3.00E-05	1265	297	832	224	832	44	7738	2978	6440	10328	5461	10375	sp	P55115	NAS15_CAEEL	29.56	477	276	9	268	1575	114	571	1.56E-52	196	P55115	reviewed	NAS15_CAEEL	Zinc metalloproteinase nas-15 (EC 3.4.24.-) (Nematode astacin 15)	nas-15 T04G9.2	Caenorhabditis elegans	571	GO:0004222; GO:0005576; GO:0006508; GO:0008270
g22266	24810.35123	-1.514406674	0.470261566	-3.220349657	0.001280343	0.005719794	9410	3878	10566	6053	16034	16510	50184	49455	57622	31792	38203	30786	sp	Q5G265	NETR_SAGLB	36.823	554	264	17	2134	3681	365	870	9.83E-88	307	Q5G265	reviewed	NETR_SAGLB	Neurotrypsin (EC 3.4.21.-) (Serine protease 12)	PRSS12	Saguinus labiatus (Red-chested mustached tamarin)	875	GO:0004252; GO:0005576; GO:0005886; GO:0006508; GO:0006887; GO:0030424
g22260	15749.63398	2.984995167	0.726990787	4.105960103	4.03E-05	0.000294382	52047	15092	8110	1534	39414	13551	4977	4646	1588	3642	9007	1688	sp	P04813	CTR2_CANLF	37.121	264	127	10	250	987	19	261	1.27E-45	159	P04813	reviewed	CTR2_CANLF	Chymotrypsinogen 2 (EC 3.4.21.1) [Cleaved into: Chymotrypsin 2 chain A; Chymotrypsin 2 chain B; Chymotrypsin 2 chain C]	CTRB1 CTRB	Canis lupus familiaris (Dog) (Canis familiaris)	263	GO:0004252; GO:0005576; GO:0006508; GO:0007586
g15917	60.30764403	3.13064577	1.033646187	3.028740211	0.002455758	0.009865322	492	25	149	0	12	14	29	17	19	0	0	8	sp	P70505	ADAM1_RAT	25.914	301	193	11	259	1122	138	421	3.18E-09	62.4	P70505	reviewed	ADAM1_RAT	Disintegrin and metalloproteinase domain-containing protein 1 (ADAM 1) (EC 3.4.24.-) (Fertilin subunit alpha)	Adam1 Adam1a Ftna	Rattus norvegicus (Rat)	789	GO:0004222; GO:0005886; GO:0006508; GO:0007339; GO:0008237; GO:0008584; GO:0009897; GO:0016020; GO:0045121; GO:0046872; GO:1990913
g6415	628.5341261	2.709408551	0.758901617	3.570171009	0.000356748	0.001915455	1669	2983	485	52	59	1189	292	137	147	47	170	289	sp	P70627	FOLH1_RAT	46.023	704	364	8	181	2274	58	751	0	629	P70627	reviewed	FOLH1_RAT	Glutamate carboxypeptidase 2 (EC 3.4.17.21) (Folate hydrolase 1) (Folylpoly-gamma-glutamate carboxypeptidase) (FGCP) (Glutamate carboxypeptidase II) (GCPII) (Membrane glutamate carboxypeptidase) (mGCP) (N-acetylated-alpha-linked acidic dipeptidase I) (NAALADase I) (Prostate-specific membrane antigen homolog) (Pteroylpoly-gamma-glutamate carboxypeptidase)	Folh1 Naalad1	Rattus norvegicus (Rat)	752	GO:0004180; GO:0004181; GO:0005886; GO:0006508; GO:0006760; GO:0008233; GO:0009986; GO:0016020; GO:0016805; GO:0030163; GO:0043065; GO:0046872; GO:1904492; GO:1904493
g18232	434.8537634	1.870309138	0.456276567	4.099069019	4.15E-05	0.000301751	457	411	356	180	602	1248	313	149	116	150	345	200	sp	Q9JLG8	CAN15_MOUSE	43.556	838	386	13	1003	3297	272	1095	0	687	Q9JLG8	reviewed	CAN15_MOUSE	Calpain-15 (EC 3.4.22.-) (Small optic lobes homolog)	Capn15 Solh	Mus musculus (Mouse)	1095	GO:0004198; GO:0005737; GO:0006508; GO:0046872
g12190	907.1383443	0.747004576	0.30687978	2.434192879	0.01492504	0.043110836	1155	1206	704	1410	687	642	920	780	1016	562	947	600	sp	P56399	UBP5_MOUSE	55.164	852	323	12	16	2406	9	856	0	902	P56399	reviewed	UBP5_MOUSE	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.4.19.12) (Deubiquitinating enzyme 5) (Isopeptidase T) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5)	Usp5 Isot	Mus musculus (Mouse)	858	GO:0004843; GO:0005634; GO:0005829; GO:0006508; GO:0008270; GO:0016579; GO:0032436; GO:0043130; GO:0098793; GO:0140251; GO:2000059
g11014	880.340805	0.703404718	0.21321109	3.299100053	0.000969953	0.004493649	1110	838	716	997	894	841	1121	697	627	1039	561	847	sp	Q14790	CASP8_HUMAN	40.392	255	134	6	913	1629	226	478	3.71E-51	185	Q14790	reviewed	CASP8_HUMAN	Caspase-8 (CASP-8) (EC 3.4.22.61) (Apoptotic cysteine protease) (Apoptotic protease Mch-5) (CAP4) (FADD-homologous ICE/ced-3-like protease) (FADD-like ICE) (FLICE) (ICE-like apoptotic protease 5) (MORT1-associated ced-3 homolog) (MACH) [Cleaved into: Caspase-8 subunit p18; Caspase-8 subunit p10]	CASP8 MCH5	Homo sapiens (Human)	479	GO:0001525; GO:0001817; GO:0004197; GO:0005123; GO:0005164; GO:0005654; GO:0005737; GO:0005739; GO:0005741; GO:0005829; GO:0005856; GO:0006508; GO:0006915; GO:0007507; GO:0008233; GO:0008234; GO:0008625; GO:0010803; GO:0030027; GO:0030101; GO:0030225; GO:0030335; GO:0031264; GO:0031265; GO:0031625; GO:0032025; GO:0032355; GO:0032496; GO:0032731; GO:0032991; GO:0034612; GO:0035877; GO:0036462; GO:0042110; GO:0042113; GO:0042802; GO:0043065; GO:0043123; GO:0043124; GO:0043525; GO:0044297; GO:0044877; GO:0045088; GO:0045471; GO:0045651; GO:0045862; GO:0051603; GO:0051604; GO:0060546; GO:0060715; GO:0070269; GO:0071260; GO:0071407; GO:0097110; GO:0097153; GO:0097190; GO:0097191; GO:0097194; GO:0097199; GO:0097202; GO:0097264; GO:0097342
g23662	201.5757247	5.152649645	1.490904512	3.456056109	0.000548141	0.002772345	227	1296	392	0	0	356	3	69	21	0	0	9	sp	P42674	BP10_PARLI	29.455	404	258	14	145	1314	59	449	3.04E-37	147	P42674	reviewed	BP10_PARLI	Blastula protease 10 (EC 3.4.24.-)	BP10	Paracentrotus lividus (Common sea urchin)	597	GO:0004222; GO:0005576; GO:0005938; GO:0006508; GO:0008270; GO:0048471
g10615	513.4827704	-0.907420912	0.164455785	-5.51771961	3.43E-08	5.80E-07	229	287	341	374	216	350	957	598	624	1176	724	805	sp	Q19AZ8	THRB_PIG	38.756	209	113	7	472	1056	376	583	1.93E-32	136	Q19AZ8	reviewed	THRB_PIG	Prothrombin (EC 3.4.21.5) (Coagulation factor II) [Cleaved into: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain]	F2	Sus scrofa (Pig)	623	GO:0004252; GO:0005509; GO:0005615; GO:0006508; GO:0006953; GO:0030168; GO:0030194; GO:0062023
g19214	75.30427524	-1.802380305	0.594613281	-3.031180708	0.002435994	0.009797328	70	23	26	41	0	30	237	144	115	204	67	120	sp	D3ZPG5	UBP30_RAT	34.177	237	100	6	781	1440	305	502	1.10E-28	122	D3ZPG5	reviewed	UBP30_RAT	Ubiquitin carboxyl-terminal hydrolase 30 (EC 3.4.19.12) (Deubiquitinating enzyme 30) (Ubiquitin thioesterase 30) (Ubiquitin-specific-processing protease 30) (Ub-specific protease 30)	Usp30	Rattus norvegicus (Rat)	517	GO:0004197; GO:0004843; GO:0005634; GO:0005739; GO:0005741; GO:0005829; GO:0006508; GO:0008053; GO:0016579; GO:0035871; GO:0044313; GO:1901525
g17537	3766.244346	6.10852301	0.744440168	8.205525804	2.30E-16	1.82E-14	5559	11793	5636	626	4794	9398	36	134	79	29	425	71	sp	F1NV61	CASP7_CHICK	39.564	321	180	3	61	1023	3	309	4.25E-79	247	F1NV61	reviewed	CASP7_CHICK	Caspase-7 (CASP-7) (EC 3.4.22.60) [Cleaved into: Caspase-7 subunit p20; Caspase-7 subunit p11]	CASP7	Gallus gallus (Chicken)	309	GO:0003723; GO:0004190; GO:0005615; GO:0005634; GO:0005737; GO:0005829; GO:0006508; GO:0042742; GO:0043525; GO:0070227; GO:0097153; GO:0097194; GO:0097200; GO:1905686
g12017	23114.44247	4.250882375	1.15940225	3.666443096	0.000245948	0.001396443	2238	24753	96413	154	811	110037	110	1338	5929	863	4671	2138	sp	P20231	TRYB2_HUMAN	31.174	247	146	6	64	762	31	267	1.05E-28	113	P20231	reviewed	TRYB2_HUMAN	Tryptase beta-2 (Tryptase-2) (EC 3.4.21.59) (Tryptase II)	TPSB2 TPS2	Homo sapiens (Human)	275	GO:0004252; GO:0005615; GO:0006508; GO:0008236; GO:0062023
g12015	8442.719969	4.472746245	1.185485753	3.772922815	0.000161346	0.000974513	545	7987	27911	43	225	47677	45	319	1842	248	1016	1161	sp	A1KXI1	BLOT3_BLOTA	41.509	159	78	5	220	678	111	260	5.01E-27	107	A1KXI1	reviewed	BLOT3_BLOTA	Trypsin Blo t 3 (EC 3.4.21.4) (Mite allergen Blo t 3) (allergen Blo t 3)		Blomia tropicalis (Mite)	266	GO:0004252; GO:0005576; GO:0006508
g13001	8177.662356	2.396850113	0.490040773	4.891123851	1.00E-06	1.16E-05	14436	5083	9601	3610	13412	19361	3171	2173	4080	1829	4104	2240	sp	Q61824	ADA12_MOUSE	39.175	776	427	14	223	2499	65	812	2.03E-162	504	Q61824	reviewed	ADA12_MOUSE	Disintegrin and metalloproteinase domain-containing protein 12 (ADAM 12) (EC 3.4.24.-) (Meltrin-alpha)	Adam12 Mltna	Mus musculus (Mouse)	903	GO:0004222; GO:0005654; GO:0005886; GO:0006508; GO:0007155; GO:0017124; GO:0046872
g16695	179076.7756	7.493856368	0.675873412	11.08766262	1.44E-28	5.78E-26	443511	191989	129620	24617	371299	512007	1950	1135	4183	786	1985	3026	sp	O77656	MMP13_BOVIN	33.333	435	236	15	202	1488	66	452	1.25E-59	207	O77656	reviewed	MMP13_BOVIN	Collagenase 3 (EC 3.4.24.-) (Matrix metalloproteinase-13) (MMP-13)	MMP13	Bos taurus (Bovine)	471	GO:0004175; GO:0004222; GO:0005509; GO:0005518; GO:0005615; GO:0006508; GO:0008270; GO:0022617; GO:0030198; GO:0030574; GO:0031012; GO:0060349
g16696	129974.8746	2.523916242	0.492253967	5.127264406	2.94E-07	3.94E-06	236222	60456	63442	67813	295566	273567	40045	37723	30964	39713	48471	49917	sp	O77656	MMP13_BOVIN	31.275	502	276	16	1	1473	1	444	3.08E-58	204	O77656	reviewed	MMP13_BOVIN	Collagenase 3 (EC 3.4.24.-) (Matrix metalloproteinase-13) (MMP-13)	MMP13	Bos taurus (Bovine)	471	GO:0004175; GO:0004222; GO:0005509; GO:0005518; GO:0005615; GO:0006508; GO:0008270; GO:0022617; GO:0030198; GO:0030574; GO:0031012; GO:0060349
g19523	146.9822298	1.739049725	0.32278339	5.387667954	7.14E-08	1.12E-06	181	204	228	103	177	230	139	76	46	121	73	54	sp	F8VPZ3	UBP32_MOUSE	50.737	339	159	5	1	1017	1	331	1.99E-104	340	F8VPZ3	reviewed	UBP32_MOUSE	Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.4.19.12) (Deubiquitinating enzyme 32) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32)	Usp32	Mus musculus (Mouse)	1604	GO:0000139; GO:0004843; GO:0005509; GO:0005794; GO:0006508; GO:0016579; GO:1904263
g19521	64.50777609	1.593355618	0.542492273	2.937102881	0.003312942	0.012606746	79	106	126	14	67	103	84	26	24	62	11	43	sp	Q8NFA0	UBP32_HUMAN	58.333	96	38	2	1	282	1509	1604	2.67E-36	132	Q8NFA0	reviewed	UBP32_HUMAN	Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.4.19.12) (Deubiquitinating enzyme 32) (Renal carcinoma antigen NY-REN-60) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32)	USP32 USP10	Homo sapiens (Human)	1604	GO:0000139; GO:0004843; GO:0005509; GO:0005794; GO:0005829; GO:0006508; GO:0016579; GO:1904263
g21915	597.5623024	1.063496107	0.307954185	3.453423139	0.00055352	0.002797091	758	861	611	321	741	668	556	391	410	621	334	515	sp	Q8BL06	UBP54_MOUSE	58.311	367	149	3	43	1140	11	374	4.37E-143	472	Q8BL06	reviewed	UBP54_MOUSE	Ubiquitin carboxyl-terminal hydrolase 54 (EC 3.4.19.12) (Ubiquitin-specific peptidase 54)	Usp54	Mus musculus (Mouse)	1588	GO:0004843; GO:0006508; GO:0016579
g2192	64427.44886	4.373415128	1.187558471	3.682694566	0.000230782	0.001322627	4058	48718	234347	348	2114	354088	370	2909	13909	1738	13353	5582	sp	P80146	SEPR_THESR	39.788	377	194	13	64	1104	35	408	1.45E-47	169	P80146	reviewed	SEPR_THESR	Extracellular serine proteinase (EC 3.4.21.-)		Thermus sp. (strain Rt41A)	410	GO:0004252; GO:0005615; GO:0006508
g2193	2003.134761	4.082821091	1.3239769	3.083755532	0.002044055	0.008453396	220	1632	9889	8	79	8597	0	122	651	54	363	267	sp	P80146	SEPR_THESR	40.323	372	189	12	82	1110	41	408	7.86E-64	212	P80146	reviewed	SEPR_THESR	Extracellular serine proteinase (EC 3.4.21.-)		Thermus sp. (strain Rt41A)	410	GO:0004252; GO:0005615; GO:0006508
g2190	769.7580321	6.300218787	1.942589873	3.243205823	0.001181928	0.005347953	22	449	3588	8	0	4010	0	72	5	4	0	51	sp	P80146	SEPR_THESR	40.053	377	195	11	58	1101	33	407	1.11E-56	193	P80146	reviewed	SEPR_THESR	Extracellular serine proteinase (EC 3.4.21.-)		Thermus sp. (strain Rt41A)	410	GO:0004252; GO:0005615; GO:0006508
g22259	677.2375282	5.817326201	0.924778697	6.290506277	3.16E-10	8.52E-09	5931	1478	301	10	214	265	141	34	5	11	0	7	sp	P80646	CTRB_GADMO	37.872	235	119	12	289	987	1	210	1.20E-35	133	P80646	reviewed	CTRB_GADMO	Chymotrypsin B (EC 3.4.21.1) [Cleaved into: Chymotrypsin B chain A; Chymotrypsin B chain B]		Gadus morhua (Atlantic cod)	245	GO:0004252; GO:0005576; GO:0006508; GO:0007586
g3166	137.979567	-2.949723515	0.39144366	-7.535499531	4.86E-14	2.64E-12	70	13	40	17	9	28	396	387	293	339	228	158	sp	Q5G266	NETR_TRAPH	33.772	456	259	15	28	1338	168	599	4.77E-55	202	Q5G266	reviewed	NETR_TRAPH	Neurotrypsin (EC 3.4.21.-) (Serine protease 12)	PRSS12	Trachypithecus phayrei (Phayre's leaf monkey)	875	GO:0004252; GO:0005886; GO:0006508; GO:0006887; GO:0030424; GO:0030425; GO:0043083; GO:0043195
g16613	252.9234539	-3.371522737	0.417927042	-8.067251923	7.19E-16	5.24E-14	18	93	42	44	18	23	772	717	316	641	615	342	sp	O05218	YWRD_BACSU	33.465	505	305	9	193	1701	49	524	6.77E-75	250	O05218	reviewed	YWRD_BACSU	Glutathione hydrolase-like YwrD proenzyme (EC 2.3.2.2) (Putative gamma-glutamyltransferase YwrD) (EC 3.4.19.13) [Cleaved into: Glutathione hydrolase-like YwrD large chain; Glutathione hydrolase-like YwrD small chain]	ywrD BSU36100	Bacillus subtilis (strain 168)	525	GO:0006508; GO:0006751; GO:0036374; GO:0103068
g10978	157.8027661	1.226875523	0.424202504	2.892193024	0.003825628	0.014210888	211	533	220	65	86	133	131	56	170	117	82	93	sp	Q08CH3	MPND_DANRE	44.977	438	207	5	115	1422	34	439	7.93E-128	382	Q08CH3	reviewed	MPND_DANRE	MPN domain-containing protein (EC 3.4.-.-)	mpnd zgc:153076	Danio rerio (Zebrafish) (Brachydanio rerio)	458	GO:0006302; GO:0006508; GO:0008237; GO:0031593; GO:0046872; GO:0070531; GO:0070552
g24127	313.072909	3.750519792	0.756259365	4.9593036	7.07E-07	8.56E-06	1731	203	241	37	457	394	50	32	29	17	55	140	sp	P37892	CBPE_LOPAM	51.942	206	94	4	1	609	225	428	1.57E-65	213	P37892	reviewed	CBPE_LOPAM	Carboxypeptidase E (CPE) (EC 3.4.17.10) (Carboxypeptidase H) (CPH) (Enkephalin convertase) (Prohormone-processing carboxypeptidase)	cpe	Lophius americanus (American angler) (Anglerfish)	454	GO:0004181; GO:0005576; GO:0006508; GO:0008270; GO:0030658
g23768	100.2809185	-0.985323586	0.28840061	-3.416510059	0.000634293	0.003126547	65	69	122	36	28	47	229	156	108	186	134	168	sp	Q8N531	FBXL6_HUMAN	37.671	438	235	11	427	1665	111	535	1.63E-69	236	Q8N531	reviewed	FBXL6_HUMAN	F-box/LRR-repeat protein 6 (F-box and leucine-rich repeat protein 6) (F-box protein FBL6) (FBL6A)	FBXL6 FBL6	Homo sapiens (Human)	539	GO:0004842; GO:0006508; GO:0019005; GO:0031146
g21337	5664.861989	6.560633475	0.60241084	10.89062984	1.28E-27	4.59E-25	19133	3976	5142	1233	9901	15463	225	100	165	86	70	213	sp	P19221	THRB_MOUSE	41.502	253	134	7	1000	1716	360	612	6.73E-55	199	P19221	reviewed	THRB_MOUSE	Prothrombin (EC 3.4.21.5) (Coagulation factor II) [Cleaved into: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain]	F2 Cf2	Mus musculus (Mouse)	618	GO:0001530; GO:0001934; GO:0004175; GO:0004252; GO:0005102; GO:0005509; GO:0005615; GO:0006508; GO:0006953; GO:0007166; GO:0007186; GO:0008201; GO:0008233; GO:0008284; GO:0008360; GO:0009897; GO:0010468; GO:0030168; GO:0030194; GO:0030307; GO:0032024; GO:0032967; GO:0042730; GO:0045861; GO:0048712; GO:0051281; GO:0051480; GO:0051838; GO:0051897; GO:0061844; GO:0062023; GO:0070053; GO:0070493; GO:0070945; GO:1900016; GO:1900182; GO:1900738; GO:1990806; GO:2000379
g10298	106.344977	7.39518487	0.970034054	7.623634285	2.47E-14	1.42E-12	390	122	77	144	137	207	6	0	9	0	0	0	sp	Q15485	FCN2_HUMAN	48.148	216	107	2	214	861	102	312	4.00E-62	202	Q15485	reviewed	FCN2_HUMAN	Ficolin-2 (37 kDa elastin-binding protein) (Collagen/fibrinogen domain-containing protein 2) (EBP-37) (Ficolin-B) (Ficolin-beta) (Hucolin) (L-ficolin) (Serum lectin p35)	FCN2 FCNL	Homo sapiens (Human)	313	GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005576; GO:0005581; GO:0005615; GO:0006508; GO:0008228; GO:0009897; GO:0043394; GO:0043654; GO:0046872; GO:0048306; GO:0050829; GO:0050830; GO:0062023; GO:0070062; GO:0072562; GO:0097367; GO:1903028; GO:1905370; GO:2001065
g11013	364.5879372	0.669553078	0.207819821	3.221796056	0.001273898	0.005696897	500	322	288	344	345	425	418	286	259	484	301	300	sp	O15519	CFLAR_HUMAN	26.471	170	116	4	286	789	9	171	2.04E-06	52.4	O15519	reviewed	CFLAR_HUMAN	CASP8 and FADD-like apoptosis regulator (Caspase homolog) (CASH) (Caspase-eight-related protein) (Casper) (Caspase-like apoptosis regulatory protein) (CLARP) (Cellular FLICE-like inhibitory protein) (c-FLIP) (FADD-like antiapoptotic molecule 1) (FLAME-1) (Inhibitor of FLICE) (I-FLICE) (MACH-related inducer of toxicity) (MRIT) (Usurpin) [Cleaved into: CASP8 and FADD-like apoptosis regulator subunit p43; CASP8 and FADD-like apoptosis regulator subunit p12]	CFLAR CASH CASP8AP1 CLARP MRIT	Homo sapiens (Human)	480	GO:0002020; GO:0005123; GO:0005737; GO:0005829; GO:0006508; GO:0006915; GO:0007519; GO:0008047; GO:0010667; GO:0010976; GO:0014732; GO:0014842; GO:0014866; GO:0030182; GO:0030216; GO:0030218; GO:0031264; GO:0031265; GO:0032869; GO:0033574; GO:0042060; GO:0043066; GO:0043123; GO:0043403; GO:0043525; GO:0044877; GO:0051092; GO:0060544; GO:0070374; GO:0071364; GO:0071392; GO:0071456; GO:0071549; GO:0071732; GO:0072126; GO:0097194; GO:0097199; GO:0097200; GO:0097342; GO:1901740; GO:1902042; GO:1903055; GO:1903427; GO:1903845; GO:1903944; GO:2000347; GO:2001237
g14507	394.7348792	-1.165733721	0.322164848	-3.618438594	0.000296386	0.00163986	199	338	246	295	98	101	704	615	427	790	876	545	sp	Q9JJ22	ERAP1_RAT	36.433	914	533	11	175	2832	30	923	0	592	Q9JJ22	reviewed	ERAP1_RAT	Endoplasmic reticulum aminopeptidase 1 (EC 3.4.11.-) (ARTS-1) (Adipocyte-derived leucine aminopeptidase) (A-LAP) (Aminopeptidase PILS) (Puromycin-insensitive leucyl-specific aminopeptidase) (PILS-AP)	Erap1 Appils Arts1	Rattus norvegicus (Rat)	930	GO:0002250; GO:0004175; GO:0004177; GO:0005138; GO:0005164; GO:0005576; GO:0005615; GO:0005737; GO:0005788; GO:0005789; GO:0006508; GO:0006509; GO:0008233; GO:0008235; GO:0008270; GO:0016020; GO:0019882; GO:0030163; GO:0042277; GO:0043171; GO:0045766; GO:0070006
g17508	201.1803002	6.263937547	2.590471854	2.418068175	0.015603153	0.044659531	62	178	1034	0	0	873	0	0	46	0	0	6	sp	P08594	AQL1_THEAQ	38.532	327	171	8	106	1023	49	366	5.34E-53	186	P08594	reviewed	AQL1_THEAQ	Aqualysin-1 (EC 3.4.21.111) (Aqualysin-I)	pstI	Thermus aquaticus	513	GO:0004252; GO:0005615; GO:0006508
g5494	33.10361149	3.155647118	1.270097076	2.484571595	0.012970742	0.038457739	51	44	21	15	2	178	0	13	11	0	0	18	sp	P15684	AMPN_RAT	35.18	776	461	16	214	2451	66	829	1.59E-144	453	P15684	reviewed	AMPN_RAT	Aminopeptidase N (AP-N) (rAPN) (EC 3.4.11.2) (Alanyl aminopeptidase) (Aminopeptidase M) (AP-M) (Kidney Zn peptidase) (KZP) (Microsomal aminopeptidase) (CD antigen CD13)	Anpep	Rattus norvegicus (Rat)	965	GO:0001525; GO:0004177; GO:0005615; GO:0005737; GO:0005793; GO:0005886; GO:0006508; GO:0008270; GO:0009897; GO:0016485; GO:0030154; GO:0031526; GO:0042277; GO:0043171; GO:0070006; GO:0070062; GO:0072237
g12113	105.2597483	-3.151406767	0.607013526	-5.191658225	2.08E-07	2.91E-06	5	55	46	15	2	10	329	237	92	246	258	221	sp	P0C872	JMJD7_MOUSE	21.484	256	159	5	37	690	29	280	3.02E-10	65.5	P0C872	reviewed	JMJD7_MOUSE	Bifunctional peptidase and (3S)-lysyl hydroxylase Jmjd7 (EC 1.14.11.63) (EC 3.4.-.-) (JmjC domain-containing protein 7) (Jumonji domain-containing protein 7) (L-lysine (3S)-hydroxylase Jmjd7)	Jmjd7	Mus musculus (Mouse)	316	GO:0004175; GO:0004177; GO:0004497; GO:0005634; GO:0005737; GO:0006508; GO:0016706; GO:0035064; GO:0046872; GO:0106155
g11949	42535.12025	4.655363123	1.178231541	3.951144542	7.78E-05	0.000518382	2947	40065	184449	289	886	207678	214	2306	9536	1108	3469	4855	sp	P07478	TRY2_HUMAN	44.503	191	98	5	58	627	24	207	5.02E-42	146	P07478	reviewed	TRY2_HUMAN	Trypsin-2 (EC 3.4.21.4) (Anionic trypsinogen) (Serine protease 2) (Trypsin II)	PRSS2 TRY2 TRYP2	Homo sapiens (Human)	247	GO:0004222; GO:0004252; GO:0005509; GO:0005576; GO:0005615; GO:0006508; GO:0007586; GO:0008236; GO:0019730; GO:0022617; GO:0030307; GO:0030574; GO:0031012; GO:0035578; GO:0045785
g18939	51.05116115	-4.216260242	1.072100351	-3.932710439	8.40E-05	0.000553395	0	17	0	4	3	3	254	8	136	58	11	269	sp	P10394	POL4_DROME	28.221	326	223	5	64	1035	890	1206	3.03E-37	146	P10394	reviewed	POL4_DROME	Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	POL ORF3	Drosophila melanogaster (Fruit fly)	1237	GO:0003676; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575
g8117	4576.271643	-0.696038273	0.256929001	-2.709068539	0.00674724	0.022650886	3165	3586	4528	3735	1596	1733	10866	7833	6921	4531	7194	4525	sp	Q96KP4	CNDP2_HUMAN	66.525	472	156	1	16	1431	4	473	0	662	Q96KP4	reviewed	CNDP2_HUMAN	Cytosolic non-specific dipeptidase (EC 3.4.13.18) (CNDP dipeptidase 2) (Glutamate carboxypeptidase-like protein 1) (Peptidase A) (Threonyl dipeptidase)	CNDP2 CN2 CPGL HEL-S-13 PEPA	Homo sapiens (Human)	475	GO:0004180; GO:0005654; GO:0005829; GO:0006508; GO:0016805; GO:0046872; GO:0070062; GO:0070573; GO:0103046