INFO [2024-03-07 20:04:39] Initializing ALASCA (v1.0.15, 2024-02-07) WARN [2024-03-07 20:04:39] Guessing effects: `fold+fold:treatment+treatment` INFO [2024-03-07 20:04:39] Will use linear mixed models! INFO [2024-03-07 20:04:39] Will use Rfast! WARN [2024-03-07 20:04:39] Converting IDs to integer values WARN [2024-03-07 20:04:39] The `fold` column is used for stratification WARN [2024-03-07 20:04:39] Converting `character` columns to factors INFO [2024-03-07 20:04:40] Scaling data with sdall ... INFO [2024-03-07 20:04:40] Calculating LMM coefficients INFO [2024-03-07 20:04:40] Reducing the number of dimensions with PCA INFO [2024-03-07 20:04:41] Keeping 46 components from initial PCA, explaining 95.24 % of variation. The limit can be changed with `reduce_dimensions.limit` INFO [2024-03-07 20:04:41] -> Finished the reduction of dimensions! WARN [2024-03-07 20:04:41] Keeping 20 of 46 components. Change `max_PC` if necessary. INFO [2024-03-07 20:04:42] Starting validation: bootstrap INFO [2024-03-07 20:04:42] - Run 1 of 100 INFO [2024-03-07 20:04:48] --- Used 6.48 seconds. Est. time remaining: 643.96 seconds INFO [2024-03-07 20:04:48] - Run 2 of 100 INFO [2024-03-07 20:04:53] --- Used 5.06 seconds. Est. time remaining: 567.28 seconds INFO [2024-03-07 20:04:53] - Run 3 of 100 INFO [2024-03-07 20:04:58] --- Used 5 seconds. Est. time remaining: 535.88 seconds INFO [2024-03-07 20:04:58] - Run 4 of 100 INFO [2024-03-07 20:05:03] --- Used 4.47 seconds. Est. time remaining: 505.13 seconds INFO [2024-03-07 20:05:03] - Run 5 of 100 INFO [2024-03-07 20:05:07] --- Used 4.54 seconds. Est. time remaining: 486.2 seconds INFO [2024-03-07 20:05:07] - Run 6 of 100 INFO [2024-03-07 20:05:12] --- Used 4.49 seconds. Est. time remaining: 471.19 seconds INFO [2024-03-07 20:05:12] - Run 7 of 100 INFO [2024-03-07 20:05:17] --- Used 4.85 seconds. 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Est. time remaining: 8.76 seconds INFO [2024-03-07 20:11:51] - Run 99 of 100 INFO [2024-03-07 20:11:55] --- Used 4.34 seconds. Est. time remaining: 4.38 seconds INFO [2024-03-07 20:11:55] - Run 100 of 100 INFO [2024-03-07 20:12:00] --- Used 4.4 seconds. Est. time remaining: 0 seconds INFO [2024-03-07 20:12:00] Calculating percentiles for score and loading INFO [2024-03-07 20:12:22] ==== ALASCA has finished ==== INFO [2024-03-07 20:12:22] To visualize the model, try `plot(, effect = 1, component = 1, type = 'effect')` INFO [2024-03-07 20:12:22] Scree plot. Selected effect (nr 1): `fold+fold:treatment+treatment`. Component: 1 and 2 and 3 and 4 and 5 and 6 and 7 and 8 and 9 and 10. INFO [2024-03-07 20:12:23] Effect plot. Selected effect (nr 1): `fold+fold:treatment+treatment`. Component: 1. WARN [2024-03-07 20:12:23] Showing 20 of 11270 variables. Adjust the number with `n_limit` INFO [2024-03-07 20:12:24] Effect plot. Selected effect (nr 1): `fold+fold:treatment+treatment`. Component: 2. WARN [2024-03-07 20:12:24] Showing 20 of 11270 variables. Adjust the number with `n_limit` INFO [2024-03-07 20:12:25] Effect plot. Selected effect (nr 1): `fold+fold:treatment+treatment`. Component: 3. WARN [2024-03-07 20:12:25] Showing 20 of 11270 variables. Adjust the number with `n_limit` INFO [2024-03-07 20:12:26] Effect plot. Selected effect (nr 1): `fold+fold:treatment+treatment`. Component: 4. WARN [2024-03-07 20:12:27] Showing 20 of 11270 variables. Adjust the number with `n_limit` INFO [2024-03-07 20:12:28] Effect plot. Selected effect (nr 1): `fold+fold:treatment+treatment`. Component: 5. WARN [2024-03-07 20:12:28] Showing 20 of 11270 variables. Adjust the number with `n_limit` INFO [2024-03-07 20:12:29] Effect plot. Selected effect (nr 1): `fold+fold:treatment+treatment`. Component: 6. WARN [2024-03-07 20:12:29] Showing 20 of 11270 variables. Adjust the number with `n_limit` INFO [2024-03-07 20:12:31] Prediction plot. Selected effect (nr 1): `fold+fold:treatment+treatment`. Component: 1. INFO [2024-03-07 20:12:31] Selecting the 5 variables with highest/lowest loading on `fold+fold:treatment+treatment` (PC1). Use `variable` to specify variables to plot INFO [2024-03-07 20:12:32] Prediction plot. Selected effect (nr 1): `fold+fold:treatment+treatment`. Component: 2. INFO [2024-03-07 20:12:32] Selecting the 5 variables with highest/lowest loading on `fold+fold:treatment+treatment` (PC2). Use `variable` to specify variables to plot INFO [2024-03-07 20:12:34] Prediction plot. Selected effect (nr 1): `fold+fold:treatment+treatment`. Component: 3. INFO [2024-03-07 20:12:34] Selecting the 5 variables with highest/lowest loading on `fold+fold:treatment+treatment` (PC3). Use `variable` to specify variables to plot INFO [2024-03-07 20:12:35] Prediction plot. Selected effect (nr 1): `fold+fold:treatment+treatment`. Component: 4. INFO [2024-03-07 20:12:35] Selecting the 5 variables with highest/lowest loading on `fold+fold:treatment+treatment` (PC4). Use `variable` to specify variables to plot INFO [2024-03-07 20:12:36] Prediction plot. Selected effect (nr 1): `fold+fold:treatment+treatment`. Component: 5. INFO [2024-03-07 20:12:36] Selecting the 5 variables with highest/lowest loading on `fold+fold:treatment+treatment` (PC5). Use `variable` to specify variables to plot INFO [2024-03-07 20:12:37] Prediction plot. Selected effect (nr 1): `fold+fold:treatment+treatment`. Component: 6. INFO [2024-03-07 20:12:37] Selecting the 5 variables with highest/lowest loading on `fold+fold:treatment+treatment` (PC6). Use `variable` to specify variables to plot INFO [2024-03-07 20:12:38] Loadings for effect number 1 and principal component(s) 5 INFO [2024-03-07 20:12:38] Loadings for effect number 1 and principal component(s) 6 INFO [2024-03-08 07:49:21] Effect plot. Selected effect (nr 1): `fold+fold:treatment+treatment`. Component: 1. WARN [2024-03-08 07:49:21] Showing 20 of 11270 variables. Adjust the number with `n_limit` INFO [2024-03-08 07:49:32] Effect plot. Selected effect (nr 1): `fold+fold:treatment+treatment`. Component: 1. WARN [2024-03-08 07:49:32] Showing 20 of 11270 variables. Adjust the number with `n_limit` INFO [2024-03-08 07:49:53] Effect plot. Selected effect (nr 1): `fold+fold:treatment+treatment`. Component: 1. WARN [2024-03-08 07:49:53] Showing 20 of 11270 variables. Adjust the number with `n_limit` INFO [2024-03-08 07:50:16] Effect plot. Selected effect (nr 1): `fold+fold:treatment+treatment`. Component: 2. WARN [2024-03-08 07:50:17] Showing 20 of 11270 variables. Adjust the number with `n_limit` INFO [2024-03-08 07:50:37] Effect plot. Selected effect (nr 1): `fold+fold:treatment+treatment`. Component: 3. WARN [2024-03-08 07:50:37] Showing 20 of 11270 variables. Adjust the number with `n_limit` INFO [2024-03-08 07:51:00] Effect plot. Selected effect (nr 1): `fold+fold:treatment+treatment`. Component: 4. WARN [2024-03-08 07:51:00] Showing 20 of 11270 variables. Adjust the number with `n_limit` INFO [2024-03-08 07:51:19] Effect plot. Selected effect (nr 1): `fold+fold:treatment+treatment`. Component: 5. WARN [2024-03-08 07:51:19] Showing 20 of 11270 variables. Adjust the number with `n_limit` INFO [2024-03-08 07:51:39] Effect plot. Selected effect (nr 1): `fold+fold:treatment+treatment`. Component: 6. WARN [2024-03-08 07:51:39] Showing 20 of 11270 variables. Adjust the number with `n_limit` INFO [2024-03-08 07:52:07] Prediction plot. Selected effect (nr 1): `fold+fold:treatment+treatment`. Component: 1. INFO [2024-03-08 07:52:07] Selecting the 5 variables with highest/lowest loading on `fold+fold:treatment+treatment` (PC1). Use `variable` to specify variables to plot INFO [2024-03-08 07:52:16] Prediction plot. Selected effect (nr 1): `fold+fold:treatment+treatment`. Component: 1. INFO [2024-03-08 07:52:16] Selecting the 5 variables with highest/lowest loading on `fold+fold:treatment+treatment` (PC1). Use `variable` to specify variables to plot INFO [2024-03-08 07:52:26] Prediction plot. Selected effect (nr 1): `fold+fold:treatment+treatment`. Component: 1. INFO [2024-03-08 07:52:26] Selecting the 5 variables with highest/lowest loading on `fold+fold:treatment+treatment` (PC1). Use `variable` to specify variables to plot INFO [2024-03-08 07:52:49] Prediction plot. Selected effect (nr 1): `fold+fold:treatment+treatment`. Component: 1. INFO [2024-03-08 07:52:49] Selecting the 6 variables with highest/lowest loading on `fold+fold:treatment+treatment` (PC1). Use `variable` to specify variables to plot INFO [2024-03-08 07:53:07] Prediction plot. Selected effect (nr 1): `fold+fold:treatment+treatment`. Component: 1. INFO [2024-03-08 07:53:07] Selecting the 10 variables with highest/lowest loading on `fold+fold:treatment+treatment` (PC1). Use `variable` to specify variables to plot INFO [2024-03-08 07:53:23] Prediction plot. Selected effect (nr 1): `fold+fold:treatment+treatment`. Component: 1. INFO [2024-03-08 07:53:23] Selecting the 10 variables with highest/lowest loading on `fold+fold:treatment+treatment` (PC1). Use `variable` to specify variables to plot INFO [2024-03-08 07:53:46] Prediction plot. Selected effect (nr 1): `fold+fold:treatment+treatment`. Component: 2. INFO [2024-03-08 07:53:46] Selecting the 10 variables with highest/lowest loading on `fold+fold:treatment+treatment` (PC2). Use `variable` to specify variables to plot INFO [2024-03-08 07:53:53] Prediction plot. Selected effect (nr 1): `fold+fold:treatment+treatment`. Component: 1. INFO [2024-03-08 07:53:53] Selecting the 10 variables with highest/lowest loading on `fold+fold:treatment+treatment` (PC1). Use `variable` to specify variables to plot INFO [2024-03-08 07:53:57] Prediction plot. Selected effect (nr 1): `fold+fold:treatment+treatment`. Component: 2. INFO [2024-03-08 07:53:57] Selecting the 10 variables with highest/lowest loading on `fold+fold:treatment+treatment` (PC2). Use `variable` to specify variables to plot INFO [2024-03-08 07:54:19] Prediction plot. Selected effect (nr 1): `fold+fold:treatment+treatment`. Component: 3. INFO [2024-03-08 07:54:19] Selecting the 10 variables with highest/lowest loading on `fold+fold:treatment+treatment` (PC3). Use `variable` to specify variables to plot INFO [2024-03-08 07:54:48] Prediction plot. Selected effect (nr 1): `fold+fold:treatment+treatment`. Component: 4. INFO [2024-03-08 07:54:48] Selecting the 10 variables with highest/lowest loading on `fold+fold:treatment+treatment` (PC4). Use `variable` to specify variables to plot INFO [2024-03-08 07:54:50] Prediction plot. Selected effect (nr 1): `fold+fold:treatment+treatment`. Component: 4. INFO [2024-03-08 07:54:50] Selecting the 10 variables with highest/lowest loading on `fold+fold:treatment+treatment` (PC4). Use `variable` to specify variables to plot INFO [2024-03-08 07:55:01] Prediction plot. Selected effect (nr 1): `fold+fold:treatment+treatment`. Component: 5. INFO [2024-03-08 07:55:01] Selecting the 10 variables with highest/lowest loading on `fold+fold:treatment+treatment` (PC5). Use `variable` to specify variables to plot INFO [2024-03-08 07:55:22] Prediction plot. Selected effect (nr 1): `fold+fold:treatment+treatment`. Component: 6. INFO [2024-03-08 07:55:22] Selecting the 10 variables with highest/lowest loading on `fold+fold:treatment+treatment` (PC6). Use `variable` to specify variables to plot INFO [2024-03-08 08:34:18] Loadings for effect number 1 and principal component(s) 1 INFO [2024-03-08 08:34:21] Loadings for effect number 1 and principal component(s) 2 INFO [2024-03-08 08:34:24] Loadings for effect number 1 and principal component(s) 3 INFO [2024-03-08 08:34:25] Loadings for effect number 1 and principal component(s) 4 INFO [2024-03-08 09:56:14] Effect plot. Selected effect (nr 1): `fold+fold:treatment+treatment`. Component: 7. WARN [2024-03-08 09:56:14] Showing 20 of 11270 variables. Adjust the number with `n_limit` INFO [2024-03-08 09:56:23] Effect plot. Selected effect (nr 1): `fold+fold:treatment+treatment`. Component: 6. WARN [2024-03-08 09:56:23] Showing 20 of 11270 variables. Adjust the number with `n_limit` INFO [2024-03-08 13:29:57] Scree plot. Selected effect (nr 1): `fold+fold:treatment+treatment`. Component: 1 and 2 and 3 and 4 and 5 and 6 and 7 and 8 and 9 and 10. INFO [2024-03-08 13:30:08] Scree plot. Selected effect (nr 1): `fold+fold:treatment+treatment`. Component: 1 and 2 and 3 and 4 and 5 and 6 and 7 and 8 and 9 and 10. INFO [2024-03-08 13:30:12] Scree plot. Selected effect (nr 1): `fold+fold:treatment+treatment`. Component: 1 and 2 and 3 and 4 and 5 and 6 and 7 and 8 and 9 and 10. INFO [2024-03-08 13:30:39] Scree plot. Selected effect (nr 1): `fold+fold:treatment+treatment`. Component: 1 and 2 and 3 and 4 and 5 and 6 and 7 and 8 and 9 and 10. INFO [2024-03-08 13:35:07] Effect plot. Selected effect (nr 1): `fold+fold:treatment+treatment`. Component: 6. WARN [2024-03-08 13:35:07] Showing 20 of 11270 variables. Adjust the number with `n_limit`