INFO  [2024-03-07 18:48:14] Initializing ALASCA (v1.0.15, 2024-02-07)
WARN  [2024-03-07 18:48:14] Guessing effects: `fold+fold:treatment+treatment`
INFO  [2024-03-07 18:48:14] Will use linear mixed models!
INFO  [2024-03-07 18:48:14] Will use Rfast!
WARN  [2024-03-07 18:48:14] Converting IDs to integer values
WARN  [2024-03-07 18:48:14] The `fold` column is used for stratification
WARN  [2024-03-07 18:48:14] Converting `character` columns to factors
INFO  [2024-03-07 18:48:14] Scaling data with sdall ...
INFO  [2024-03-07 18:48:14] Calculating LMM coefficients
INFO  [2024-03-07 18:48:14] Reducing the number of dimensions with PCA
INFO  [2024-03-07 18:48:16] Keeping 46 components from initial PCA, explaining 95.24 % of variation. The limit can be changed with `reduce_dimensions.limit`
INFO  [2024-03-07 18:48:16] -> Finished the reduction of dimensions!
WARN  [2024-03-07 18:48:16] Keeping 20 of 46 components. Change `max_PC` if necessary.
INFO  [2024-03-07 18:48:17] Starting validation: bootstrap
INFO  [2024-03-07 18:48:17] - Run 1 of 100
INFO  [2024-03-07 18:48:21] --- Used 4.47 seconds. Est. time remaining: 444.81 seconds
INFO  [2024-03-07 18:48:21] - Run 2 of 100
INFO  [2024-03-07 18:48:26] --- Used 4.46 seconds. Est. time remaining: 438.71 seconds
INFO  [2024-03-07 18:48:26] - Run 3 of 100
INFO  [2024-03-07 18:48:30] --- Used 4.49 seconds. Est. time remaining: 434.83 seconds
INFO  [2024-03-07 18:48:30] - Run 4 of 100
INFO  [2024-03-07 18:48:35] --- Used 4.41 seconds. Est. time remaining: 428.61 seconds
INFO  [2024-03-07 18:48:35] - Run 5 of 100
INFO  [2024-03-07 18:48:39] --- Used 4.35 seconds. Est. time remaining: 422.04 seconds
INFO  [2024-03-07 18:48:39] - Run 6 of 100
INFO  [2024-03-07 18:48:44] --- Used 4.65 seconds. Est. time remaining: 420.87 seconds
INFO  [2024-03-07 18:48:44] - Run 7 of 100
INFO  [2024-03-07 18:48:48] --- Used 4.44 seconds. Est. time remaining: 415.85 seconds
INFO  [2024-03-07 18:48:48] - Run 8 of 100
INFO  [2024-03-07 18:48:53] --- Used 4.46 seconds. Est. time remaining: 411.3 seconds
INFO  [2024-03-07 18:48:53] - Run 9 of 100
INFO  [2024-03-07 18:48:57] --- Used 4.4 seconds. Est. time remaining: 406.13 seconds
INFO  [2024-03-07 18:48:57] - Run 10 of 100
INFO  [2024-03-07 18:49:01] --- Used 4.4 seconds. Est. time remaining: 401.13 seconds
INFO  [2024-03-07 18:49:01] - Run 11 of 100
INFO  [2024-03-07 18:49:06] --- Used 4.52 seconds. Est. time remaining: 397.16 seconds
INFO  [2024-03-07 18:49:06] - Run 12 of 100
INFO  [2024-03-07 18:49:10] --- Used 4.34 seconds. Est. time remaining: 391.77 seconds
INFO  [2024-03-07 18:49:10] - Run 13 of 100
INFO  [2024-03-07 18:49:15] --- Used 4.27 seconds. Est. time remaining: 386.16 seconds
INFO  [2024-03-07 18:49:15] - Run 14 of 100
INFO  [2024-03-07 18:49:19] --- Used 4.37 seconds. Est. time remaining: 381.29 seconds
INFO  [2024-03-07 18:49:19] - Run 15 of 100
INFO  [2024-03-07 18:49:24] --- Used 5.25 seconds. Est. time remaining: 381.47 seconds
INFO  [2024-03-07 18:49:24] - Run 16 of 100
INFO  [2024-03-07 18:49:29] --- Used 4.36 seconds. Est. time remaining: 376.33 seconds
INFO  [2024-03-07 18:49:29] - Run 17 of 100
INFO  [2024-03-07 18:49:33] --- Used 4.39 seconds. Est. time remaining: 371.42 seconds
INFO  [2024-03-07 18:49:33] - Run 18 of 100
INFO  [2024-03-07 18:49:37] --- Used 4.37 seconds. Est. time remaining: 366.48 seconds
INFO  [2024-03-07 18:49:37] - Run 19 of 100
INFO  [2024-03-07 18:49:42] --- Used 4.39 seconds. Est. time remaining: 361.68 seconds
INFO  [2024-03-07 18:49:42] - Run 20 of 100
INFO  [2024-03-07 18:49:46] --- Used 4.42 seconds. Est. time remaining: 357.02 seconds
INFO  [2024-03-07 18:49:46] - Run 21 of 100
INFO  [2024-03-07 18:49:51] --- Used 4.43 seconds. Est. time remaining: 352.45 seconds
INFO  [2024-03-07 18:49:51] - Run 22 of 100
INFO  [2024-03-07 18:49:55] --- Used 4.53 seconds. Est. time remaining: 348.23 seconds
INFO  [2024-03-07 18:49:55] - Run 23 of 100
INFO  [2024-03-07 18:49:59] --- Used 4.36 seconds. Est. time remaining: 343.38 seconds
INFO  [2024-03-07 18:49:59] - Run 24 of 100
INFO  [2024-03-07 18:50:04] --- Used 4.3 seconds. Est. time remaining: 338.45 seconds
INFO  [2024-03-07 18:50:04] - Run 25 of 100
INFO  [2024-03-07 18:50:08] --- Used 4.55 seconds. Est. time remaining: 334.28 seconds
INFO  [2024-03-07 18:50:08] - Run 26 of 100
INFO  [2024-03-07 18:50:13] --- Used 4.44 seconds. Est. time remaining: 329.78 seconds
INFO  [2024-03-07 18:50:13] - Run 27 of 100