INFO  [2024-03-07 18:30:22] Initializing ALASCA (v1.0.15, 2024-02-07)
WARN  [2024-03-07 18:30:22] Guessing effects: `fold+fold:treatment+treatment`
INFO  [2024-03-07 18:30:22] Will use linear mixed models!
INFO  [2024-03-07 18:30:22] Will use Rfast!
WARN  [2024-03-07 18:30:22] Converting IDs to integer values
WARN  [2024-03-07 18:30:22] The `fold` column is used for stratification
WARN  [2024-03-07 18:30:22] Converting `character` columns to factors
INFO  [2024-03-07 18:30:22] Scaling data with sdall ...
INFO  [2024-03-07 18:30:23] Calculating LMM coefficients
INFO  [2024-03-07 18:30:23] Reducing the number of dimensions with PCA
INFO  [2024-03-07 18:30:24] Keeping 36 components from initial PCA, explaining 95.31 % of variation. The limit can be changed with `reduce_dimensions.limit`
INFO  [2024-03-07 18:30:24] -> Finished the reduction of dimensions!
WARN  [2024-03-07 18:30:24] Keeping 20 of 36 components. Change `max_PC` if necessary.
INFO  [2024-03-07 18:30:25] Starting validation: bootstrap
INFO  [2024-03-07 18:30:25] - Run 1 of 100
INFO  [2024-03-07 18:30:30] --- Used 4.24 seconds. Est. time remaining: 421.84 seconds
INFO  [2024-03-07 18:30:30] - Run 2 of 100
INFO  [2024-03-07 18:30:34] --- Used 3.96 seconds. Est. time remaining: 402.69 seconds
INFO  [2024-03-07 18:30:34] - Run 3 of 100
INFO  [2024-03-07 18:30:38] --- Used 4.06 seconds. Est. time remaining: 396.94 seconds
INFO  [2024-03-07 18:30:38] - Run 4 of 100
INFO  [2024-03-07 18:30:42] --- Used 4 seconds. Est. time remaining: 390.53 seconds
INFO  [2024-03-07 18:30:42] - Run 5 of 100
INFO  [2024-03-07 18:30:46] --- Used 4.14 seconds. Est. time remaining: 387.89 seconds
INFO  [2024-03-07 18:30:46] - Run 6 of 100
INFO  [2024-03-07 18:30:50] --- Used 4.06 seconds. Est. time remaining: 383.53 seconds
INFO  [2024-03-07 18:30:50] - Run 7 of 100
INFO  [2024-03-07 18:30:54] --- Used 4.13 seconds. Est. time remaining: 380.13 seconds
INFO  [2024-03-07 18:30:54] - Run 8 of 100
INFO  [2024-03-07 18:30:58] --- Used 4.06 seconds. Est. time remaining: 375.68 seconds
INFO  [2024-03-07 18:30:58] - Run 9 of 100
INFO  [2024-03-07 18:31:02] --- Used 4.09 seconds. Est. time remaining: 371.62 seconds
INFO  [2024-03-07 18:31:02] - Run 10 of 100
INFO  [2024-03-07 18:31:06] --- Used 4.15 seconds. Est. time remaining: 368.16 seconds
INFO  [2024-03-07 18:31:06] - Run 11 of 100
INFO  [2024-03-07 18:31:10] --- Used 3.89 seconds. Est. time remaining: 362.45 seconds
INFO  [2024-03-07 18:31:10] - Run 12 of 100
INFO  [2024-03-07 18:31:14] --- Used 4.06 seconds. Est. time remaining: 358.24 seconds
INFO  [2024-03-07 18:31:14] - Run 13 of 100
INFO  [2024-03-07 18:31:18] --- Used 3.99 seconds. Est. time remaining: 353.68 seconds
INFO  [2024-03-07 18:31:18] - Run 14 of 100
INFO  [2024-03-07 18:31:22] --- Used 4.1 seconds. Est. time remaining: 349.8 seconds
INFO  [2024-03-07 18:31:22] - Run 15 of 100
INFO  [2024-03-07 18:31:26] --- Used 3.96 seconds. Est. time remaining: 345.14 seconds
INFO  [2024-03-07 18:31:26] - Run 16 of 100
INFO  [2024-03-07 18:31:30] --- Used 4 seconds. Est. time remaining: 340.78 seconds
INFO  [2024-03-07 18:31:30] - Run 17 of 100
INFO  [2024-03-07 18:31:35] --- Used 5.05 seconds. Est. time remaining: 341.55 seconds
INFO  [2024-03-07 18:31:35] - Run 18 of 100
INFO  [2024-03-07 18:31:39] --- Used 3.95 seconds. Est. time remaining: 336.68 seconds
INFO  [2024-03-07 18:31:39] - Run 19 of 100
INFO  [2024-03-07 18:31:43] --- Used 4.08 seconds. Est. time remaining: 332.47 seconds
INFO  [2024-03-07 18:31:43] - Run 20 of 100
INFO  [2024-03-07 18:31:47] --- Used 4.03 seconds. Est. time remaining: 328.07 seconds
INFO  [2024-03-07 18:31:47] - Run 21 of 100
INFO  [2024-03-07 18:31:51] --- Used 4.04 seconds. Est. time remaining: 323.76 seconds
INFO  [2024-03-07 18:31:51] - Run 22 of 100
INFO  [2024-03-07 18:31:56] --- Used 4.2 seconds. Est. time remaining: 320.03 seconds
INFO  [2024-03-07 18:31:56] - Run 23 of 100