🚀 Full Dataset Context-Dependent Analysis Report
📊 Executive Summary
This report presents the results of a comprehensive context-dependent regulatory analysis
performed on the complete dataset, analyzing 100% of all available data including
36,084 genes, 15,900 lncRNAs, 51 miRNAs, and 249 methylation sites across 40 samples.
🎯 Analysis Scope & Performance
36,084
Total Genes Analyzed
6,171,026
Total Interactions
1,010,968
Context-Dependent
16.4%
Context-Dependence Rate
📈 Key Performance Metrics
0.069
Methylation-miRNA Improvement
0.042
lncRNA-miRNA Improvement
99.0%
Multi-Way Success Rate
📊 Context-Dependent Interaction Distribution
📈 Interaction Improvements Analysis
💪 Context Strength Comparison
🔗 Multi-Way Interaction Success
📊 Overall Performance Summary
🏆 Top Context-Dependent Interactions
Top Methylation-miRNA Context Interactions
FUN_030163 | methylation_CpG_ptg000011l_8393332 + mirna_Cluster_12081 |
Improvement: 0.757
FUN_036141 | methylation_CpG_ptg000011l_8393332 + mirna_Cluster_12081 |
Improvement: 0.757
FUN_037387 | methylation_CpG_ptg000011l_8393332 + mirna_Cluster_12081 |
Improvement: 0.757
FUN_011084 | methylation_CpG_ptg000011l_8393332 + mirna_Cluster_12081 |
Improvement: 0.757
FUN_016825 | methylation_CpG_ptg000011l_8393332 + mirna_Cluster_12081 |
Improvement: 0.757
Top lncRNA-miRNA Context Interactions
FUN_035125 | lncrna_lncRNA_38105 + mirna_Cluster_1951 |
Improvement: 0.581
FUN_040982 | lncrna_lncRNA_38105 + mirna_Cluster_1951 |
Improvement: 0.581
FUN_042194 | lncrna_lncRNA_38105 + mirna_Cluster_1951 |
Improvement: 0.581
FUN_031114 | lncrna_lncRNA_38105 + mirna_Cluster_1951 |
Improvement: 0.581
FUN_031144 | lncrna_lncRNA_38105 + mirna_Cluster_1951 |
Improvement: 0.581
Top Multi-Way Regulatory Networks
FUN_027118 |
Improvement: 0.930
FUN_026689 |
Improvement: 0.930
FUN_016064 |
Improvement: 0.930
FUN_028898 |
Improvement: 0.930
FUN_011752 |
Improvement: 0.930
🔍 Key Insights & Findings
🎯 Comprehensive Coverage
This analysis represents the first time the complete dataset has been analyzed,
providing unprecedented insights into regulatory networks across all available data.
⚡ High Performance
Utilizing 48 parallel CPU cores and optimized algorithms, the analysis processed
over 6 million regulatory interactions efficiently.
🔬 Context-Dependent Discovery
Identified 1,010,968 context-dependent interactions, revealing complex regulatory
mechanisms that depend on cellular context.
🌐 Multi-Way Networks
Successfully analyzed 36,084 multi-way regulatory networks with a 99.0% success rate,
uncovering complex regulatory hierarchies.
📋 Technical Details
Analysis Parameters
- Dataset Coverage: 100% of all available data
- Parallel Processing: 48 CPU cores
- Memory Optimization: Vectorized operations and batch processing
- Quality Control: Statistical significance testing (p < 0.1)
- Context Analysis: High/low miRNA and methylation contexts