[Fri Oct 9 09:23:11 PDT 2026] Och (Ostrea chilensis) proteins 21444 transcripts -> 21444 genes [Fri Oct 9 09:23:17 PDT 2026] Olur (Ostrea lurida) proteins 32210 transcripts -> 32210 genes diamond v2.2.8.188 (C) Max Planck Society for the Advancement of Science, Benjamin J. Buchfink, University of Tuebingen Documentation, support and updates available at http://www.diamondsearch.org Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021) #CPU threads: 32 Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1) Database input file: output/14-meth-compare/orthologs/Olur.genes.faa Opening the database file... [0s] Loading sequences... [0.014s] Masking sequences... [0.053s] Writing sequences... [0.008s] Hashing sequences... [0.002s] Loading sequences... [0s] Writing trailer... [0.001s] Closing the input file... [0s] Closing the database file... [0.002s] Database sequences 32210 Database letters 9689607 Database hash 7daa0f5b6e16d9a81af7c7168d6463ff Total time 0.084000s [Fri Oct 9 09:25:59 PDT 2026] diamond Och -> Olur diamond v2.2.8.188 (C) Max Planck Society for the Advancement of Science, Benjamin J. Buchfink, University of Tuebingen Documentation, support and updates available at http://www.diamondsearch.org Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021) #CPU threads: 32 Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1) Temporary directory: output/14-meth-compare/orthologs/ #Target sequences to report alignments for: 1 Opening the database... [0s] Database: output/14-meth-compare/orthologs/Olur (type: Diamond database, sequences: 32'210, letters: 9'689'607, build version: 188) Block size = 2'000'000'000 Opening the input file... [0.275s] Opening the output file... [0s] Loading query sequences... [0.014s] Loaded 8'858'543 bytes from disk at 593.02 MB/s Masking queries... [0.068s] Masked letters: tantan: 700'318 seg: 0 motif: 0 Algorithm: Double-indexed Building query histograms... [0.114s] Seeking in database... [0s] Loading reference sequences... [0.014s] Masking reference... [0.027s] Masked letters: tantan: 372'447 seg: 0 motif: 0 Initializing temporary storage... [0.01s] Building reference histograms... [0.155s] Allocating buffers... [0s] Processing query block 1, reference block 1/1, shape 1/16, index chunk 1/4. Building reference seed array... [0.026s] Building query seed array... [0.02s] Computing hash join... [0.017s] Masking low complexity seeds... [0.004s] Searching alignments... [0.034s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 1/16, index chunk 2/4. Building reference seed array... [0.017s] Building query seed array... [0.021s] Computing hash join... [0.005s] Masking low complexity seeds... [0.004s] Searching alignments... [0.025s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 1/16, index chunk 3/4. Building reference seed array... [0.01s] Building query seed array... [0.013s] Computing hash join... [0.004s] Masking low complexity seeds... [0.003s] Searching alignments... [0.026s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 1/16, index chunk 4/4. Building reference seed array... [0.016s] Building query seed array... [0.011s] Computing hash join... [0.005s] Masking low complexity seeds... [0.003s] Searching alignments... [0.027s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 2/16, index chunk 1/4. Building reference seed array... [0.02s] Building query seed array... [0.017s] Computing hash join... [0.004s] Masking low complexity seeds... [0.003s] Searching alignments... [0.023s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 2/16, index chunk 2/4. Building reference seed array... [0.026s] Building query seed array... [0.008s] Computing hash join... [0.004s] Masking low complexity seeds... [0.003s] Searching alignments... [0.025s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 2/16, index chunk 3/4. Building reference seed array... [0.01s] Building query seed array... [0.016s] Computing hash join... [0.004s] Masking low complexity seeds... [0.003s] Searching alignments... [0.022s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 2/16, index chunk 4/4. Building reference seed array... [0.017s] Building query seed array... [0.019s] Computing hash join... [0.004s] Masking low complexity seeds... [0.003s] Searching alignments... [0.02s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 3/16, index chunk 1/4. Building reference seed array... [0.013s] Building query seed array... [0.014s] Computing hash join... [0.004s] Masking low complexity seeds... [0.003s] Searching alignments... [0.024s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 3/16, index chunk 2/4. Building reference seed array... [0.021s] Building query seed array... [0.025s] Computing hash join... [0.004s] Masking low complexity seeds... [0.003s] Searching alignments... [0.025s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 3/16, index chunk 3/4. Building reference seed array... [0.019s] Building query seed array... [0.017s] Computing hash join... [0.004s] Masking low complexity seeds... [0.003s] Searching alignments... [0.022s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 3/16, index chunk 4/4. Building reference seed array... [0.019s] Building query seed array... [0.019s] Computing hash join... [0.004s] Masking low complexity seeds... [0.003s] Searching alignments... [0.027s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 4/16, index chunk 1/4. Building reference seed array... [0.017s] Building query seed array... [0.019s] Computing hash join... [0.004s] Masking low complexity seeds... [0.004s] Searching alignments... [0.026s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 4/16, index chunk 2/4. Building reference seed array... [0.028s] Building query seed array... [0.016s] Computing hash join... [0.004s] Masking low complexity seeds... [0.004s] Searching alignments... [0.023s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 4/16, index chunk 3/4. Building reference seed array... [0.018s] Building query seed array... [0.016s] Computing hash join... [0.004s] Masking low complexity seeds... [0.003s] Searching alignments... [0.022s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 4/16, index chunk 4/4. Building reference seed array... [0.02s] Building query seed array... [0.016s] Computing hash join... [0.004s] Masking low complexity seeds... [0.004s] Searching alignments... [0.024s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 5/16, index chunk 1/4. Building reference seed array... [0.019s] Building query seed array... [0.019s] Computing hash join... [0.004s] Masking low complexity seeds... [0.003s] Searching alignments... [0.026s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 5/16, index chunk 2/4. Building reference seed array... [0.016s] Building query seed array... [0.011s] Computing hash join... [0.004s] Masking low complexity seeds... [0.004s] Searching alignments... [0.018s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 5/16, index chunk 3/4. Building reference seed array... [0.016s] Building query seed array... [0.008s] Computing hash join... [0.003s] Masking low complexity seeds... [0.003s] Searching alignments... [0.024s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 5/16, index chunk 4/4. Building reference seed array... [0.018s] Building query seed array... [0.019s] Computing hash join... [0.004s] Masking low complexity seeds... [0.002s] Searching alignments... [0.025s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 6/16, index chunk 1/4. Building reference seed array... [0.016s] Building query seed array... [0.016s] Computing hash join... [0.004s] Masking low complexity seeds... [0.004s] Searching alignments... [0.02s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 6/16, index chunk 2/4. Building reference seed array... [0.016s] Building query seed array... [0.014s] Computing hash join... [0.004s] Masking low complexity seeds... [0.004s] Searching alignments... [0.021s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 6/16, index chunk 3/4. Building reference seed array... [0.022s] Building query seed array... [0.016s] Computing hash join... [0.005s] Masking low complexity seeds... [0.004s] Searching alignments... [0.029s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 6/16, index chunk 4/4. Building reference seed array... [0.024s] Building query seed array... [0.015s] Computing hash join... [0.004s] Masking low complexity seeds... [0.004s] Searching alignments... [0.019s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 7/16, index chunk 1/4. Building reference seed array... [0.023s] Building query seed array... [0.009s] Computing hash join... [0.004s] Masking low complexity seeds... [0.004s] Searching alignments... [0.026s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 7/16, index chunk 2/4. Building reference seed array... [0.016s] Building query seed array... [0.019s] Computing hash join... [0.004s] Masking low complexity seeds... [0.004s] Searching alignments... [0.027s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 7/16, index chunk 3/4. Building reference seed array... [0.019s] Building query seed array... [0.013s] Computing hash join... [0.004s] Masking low complexity seeds... [0.004s] Searching alignments... [0.022s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 7/16, index chunk 4/4. Building reference seed array... [0.019s] Building query seed array... [0.011s] Computing hash join... [0.004s] Masking low complexity seeds... [0.003s] Searching alignments... [0.022s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 8/16, index chunk 1/4. Building reference seed array... [0.016s] Building query seed array... [0.019s] Computing hash join... [0.004s] Masking low complexity seeds... [0.004s] Searching alignments... [0.023s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 8/16, index chunk 2/4. Building reference seed array... [0.019s] Building query seed array... [0.014s] Computing hash join... [0.004s] Masking low complexity seeds... [0.005s] Searching alignments... [0.022s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 8/16, index chunk 3/4. Building reference seed array... [0.022s] Building query seed array... [0.014s] Computing hash join... [0.004s] Masking low complexity seeds... [0.004s] Searching alignments... [0.027s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 8/16, index chunk 4/4. Building reference seed array... [0.032s] Building query seed array... [0.024s] Computing hash join... [0.004s] Masking low complexity seeds... [0.004s] Searching alignments... [0.022s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 9/16, index chunk 1/4. Building reference seed array... [0.022s] Building query seed array... [0.019s] Computing hash join... [0.004s] Masking low complexity seeds... [0.003s] Searching alignments... [0.024s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 9/16, index chunk 2/4. Building reference seed array... [0.029s] Building query seed array... [0.019s] Computing hash join... [0.004s] Masking low complexity seeds... [0.003s] Searching alignments... [0.019s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 9/16, index chunk 3/4. Building reference seed array... [0.02s] Building query seed array... [0.019s] Computing hash join... [0.004s] Masking low complexity seeds... [0.003s] Searching alignments... [0.02s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 9/16, index chunk 4/4. Building reference seed array... [0.016s] Building query seed array... [0.016s] Computing hash join... [0.004s] Masking low complexity seeds... [0.003s] Searching alignments... [0.022s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 10/16, index chunk 1/4. Building reference seed array... [0.019s] Building query seed array... [0.019s] Computing hash join... [0.004s] Masking low complexity seeds... [0.003s] Searching alignments... [0.028s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 10/16, index chunk 2/4. Building reference seed array... [0.023s] Building query seed array... [0.021s] Computing hash join... [0.006s] Masking low complexity seeds... [0.003s] Searching alignments... [0.027s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 10/16, index chunk 3/4. Building reference seed array... [0.02s] Building query seed array... [0.016s] Computing hash join... [0.004s] Masking low complexity seeds... [0.003s] Searching alignments... [0.024s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 10/16, index chunk 4/4. Building reference seed array... [0.026s] Building query seed array... [0.016s] Computing hash join... [0.004s] Masking low complexity seeds... [0.003s] Searching alignments... [0.026s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 11/16, index chunk 1/4. Building reference seed array... [0.02s] Building query seed array... [0.014s] Computing hash join... [0.004s] Masking low complexity seeds... [0.004s] Searching alignments... [0.026s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 11/16, index chunk 2/4. Building reference seed array... [0.022s] Building query seed array... [0.011s] Computing hash join... [0.005s] Masking low complexity seeds... [0.004s] Searching alignments... [0.027s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 11/16, index chunk 3/4. Building reference seed array... [0.016s] Building query seed array... [0.033s] Computing hash join... [0.004s] Masking low complexity seeds... [0.004s] Searching alignments... [0.025s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 11/16, index chunk 4/4. Building reference seed array... [0.017s] Building query seed array... [0.016s] Computing hash join... [0.004s] Masking low complexity seeds... [0.004s] Searching alignments... [0.064s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 12/16, index chunk 1/4. Building reference seed array... [0.019s] Building query seed array... [0.021s] Computing hash join... [0.004s] Masking low complexity seeds... [0.003s] Searching alignments... [0.024s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 12/16, index chunk 2/4. Building reference seed array... [0.016s] Building query seed array... [0.015s] Computing hash join... [0.004s] Masking low complexity seeds... [0.004s] Searching alignments... [0.022s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 12/16, index chunk 3/4. Building reference seed array... [0.01s] Building query seed array... [0.022s] Computing hash join... [0.004s] Masking low complexity seeds... [0.003s] Searching alignments... [0.023s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 12/16, index chunk 4/4. Building reference seed array... [0.019s] Building query seed array... [0.016s] Computing hash join... [0.003s] Masking low complexity seeds... [0.004s] Searching alignments... [0.021s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 13/16, index chunk 1/4. Building reference seed array... [0.029s] Building query seed array... [0.016s] Computing hash join... [0.008s] Masking low complexity seeds... [0.003s] Searching alignments... [0.024s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 13/16, index chunk 2/4. Building reference seed array... [0.019s] Building query seed array... [0.014s] Computing hash join... [0.004s] Masking low complexity seeds... [0.003s] Searching alignments... [0.022s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 13/16, index chunk 3/4. Building reference seed array... [0.02s] Building query seed array... [0.017s] Computing hash join... [0.009s] Masking low complexity seeds... [0.003s] Searching alignments... [0.024s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 13/16, index chunk 4/4. Building reference seed array... [0.014s] Building query seed array... [0.016s] Computing hash join... [0.004s] Masking low complexity seeds... [0.005s] Searching alignments... [0.024s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 14/16, index chunk 1/4. Building reference seed array... [0.02s] Building query seed array... [0.016s] Computing hash join... [0.004s] Masking low complexity seeds... [0.003s] Searching alignments... [0.026s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 14/16, index chunk 2/4. Building reference seed array... [0.019s] Building query seed array... [0.017s] Computing hash join... [0.004s] Masking low complexity seeds... [0.003s] Searching alignments... [0.025s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 14/16, index chunk 3/4. Building reference seed array... [0.026s] Building query seed array... [0.014s] Computing hash join... [0.004s] Masking low complexity seeds... [0.003s] Searching alignments... [0.022s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 14/16, index chunk 4/4. Building reference seed array... [0.025s] Building query seed array... [0.014s] Computing hash join... [0.004s] Masking low complexity seeds... [0.004s] Searching alignments... [0.019s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 15/16, index chunk 1/4. Building reference seed array... [0.031s] Building query seed array... [0.011s] Computing hash join... [0.004s] Masking low complexity seeds... [0.004s] Searching alignments... [0.028s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 15/16, index chunk 2/4. Building reference seed array... [0.029s] Building query seed array... [0.019s] Computing hash join... [0.004s] Masking low complexity seeds... [0.004s] Searching alignments... [0.026s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 15/16, index chunk 3/4. Building reference seed array... [0.016s] Building query seed array... [0.011s] Computing hash join... [0.005s] Masking low complexity seeds... [0.004s] Searching alignments... [0.026s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 15/16, index chunk 4/4. Building reference seed array... [0.019s] Building query seed array... [0.011s] Computing hash join... [0.009s] Masking low complexity seeds... [0.004s] Searching alignments... [0.022s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 16/16, index chunk 1/4. Building reference seed array... [0.023s] Building query seed array... [0.017s] Computing hash join... [0.004s] Masking low complexity seeds... [0.004s] Searching alignments... [0.029s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 16/16, index chunk 2/4. Building reference seed array... [0.015s] Building query seed array... [0.018s] Computing hash join... [0.005s] Masking low complexity seeds... [0.003s] Searching alignments... [0.023s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 16/16, index chunk 3/4. Building reference seed array... [0.029s] Building query seed array... [0.011s] Computing hash join... [0.004s] Masking low complexity seeds... [0.004s] Searching alignments... [0.024s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 16/16, index chunk 4/4. Building reference seed array... [0.02s] Building query seed array... [0.016s] Computing hash join... [0.004s] Masking low complexity seeds... [0.004s] Searching alignments... [0.025s] Deallocating memory... [0s] Deallocating buffers... [0s] Clearing query masking... [0.083s] Computing alignments... [0.979s] Deallocating reference... [0s] Loading reference sequences... [0s] Deallocating buffers... [0s] Deallocating queries... [0s] Loading query sequences... [0.001s] Closing the input file... [0s] Closing the output file... [0s] Closing the database... [0s] Cleaning up... [0s] Total time = 6.438s Reported 15'661 pairwise alignments, 15'661 HSPs. 15'661 queries aligned. diamond v2.2.8.188 (C) Max Planck Society for the Advancement of Science, Benjamin J. Buchfink, University of Tuebingen Documentation, support and updates available at http://www.diamondsearch.org Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021) #CPU threads: 32 Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1) Database input file: output/14-meth-compare/orthologs/Och.genes.faa Opening the database file... [0s] Loading sequences... [0.127s] Masking sequences... [0.079s] Writing sequences... [0.007s] Hashing sequences... [0.002s] Loading sequences... [0.001s] Writing trailer... [0s] Closing the input file... [0s] Closing the database file... [0.024s] Database sequences 21444 Database letters 8622659 Database hash 441bc3f057f7947cda14c3f6973bf4ed Total time 0.242000s [Fri Oct 9 09:26:06 PDT 2026] diamond Olur -> Och diamond v2.2.8.188 (C) Max Planck Society for the Advancement of Science, Benjamin J. Buchfink, University of Tuebingen Documentation, support and updates available at http://www.diamondsearch.org Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021) #CPU threads: 32 Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1) Temporary directory: output/14-meth-compare/orthologs/ #Target sequences to report alignments for: 1 Opening the database... [0s] Database: output/14-meth-compare/orthologs/Och (type: Diamond database, sequences: 21'444, letters: 8'622'659, build version: 188) Block size = 2'000'000'000 Opening the input file... [0s] Opening the output file... [0.003s] Loading query sequences... [0.013s] Loaded 10'204'967 bytes from disk at 720.371 MB/s Masking queries... [0.072s] Masked letters: tantan: 372'447 seg: 0 motif: 0 Algorithm: Double-indexed Building query histograms... [0.119s] Seeking in database... [0s] Loading reference sequences... [0.012s] Masking reference... [0.044s] Masked letters: tantan: 700'318 seg: 0 motif: 0 Initializing temporary storage... [0.004s] Building reference histograms... [0.108s] Allocating buffers... [0.001s] Processing query block 1, reference block 1/1, shape 1/16, index chunk 1/4. Building reference seed array... [0.019s] Building query seed array... [0.014s] Computing hash join... [0.015s] Masking low complexity seeds... [0.005s] Searching alignments... [0.029s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 1/16, index chunk 2/4. Building reference seed array... [0.023s] Building query seed array... [0.02s] Computing hash join... [0.005s] Masking low complexity seeds... [0.004s] Searching alignments... [0.03s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 1/16, index chunk 3/4. Building reference seed array... [0.018s] Building query seed array... [0.043s] Computing hash join... [0.004s] Masking low complexity seeds... [0.004s] Searching alignments... [0.026s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 1/16, index chunk 4/4. Building reference seed array... [0.018s] Building query seed array... [0.014s] Computing hash join... [0.005s] Masking low complexity seeds... [0.003s] Searching alignments... [0.023s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 2/16, index chunk 1/4. Building reference seed array... [0.017s] Building query seed array... [0.011s] Computing hash join... [0.005s] Masking low complexity seeds... [0.005s] Searching alignments... [0.024s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 2/16, index chunk 2/4. Building reference seed array... [0.021s] Building query seed array... [0.011s] Computing hash join... [0.005s] Masking low complexity seeds... [0.004s] Searching alignments... [0.022s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 2/16, index chunk 3/4. Building reference seed array... [0.015s] Building query seed array... [0.015s] Computing hash join... [0.005s] Masking low complexity seeds... [0.003s] Searching alignments... [0.021s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 2/16, index chunk 4/4. Building reference seed array... [0.018s] Building query seed array... [0.015s] Computing hash join... [0.004s] Masking low complexity seeds... [0.003s] Searching alignments... [0.027s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 3/16, index chunk 1/4. Building reference seed array... [0.012s] Building query seed array... [0.019s] Computing hash join... [0.005s] Masking low complexity seeds... [0.004s] Searching alignments... [0.023s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 3/16, index chunk 2/4. Building reference seed array... [0.018s] Building query seed array... [0.023s] Computing hash join... [0.005s] Masking low complexity seeds... [0.003s] Searching alignments... [0.022s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 3/16, index chunk 3/4. Building reference seed array... [0.018s] Building query seed array... [0.022s] Computing hash join... [0.004s] Masking low complexity seeds... [0.003s] Searching alignments... [0.025s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 3/16, index chunk 4/4. Building reference seed array... [0.018s] Building query seed array... [0.016s] Computing hash join... [0.004s] Masking low complexity seeds... [0.003s] Searching alignments... [0.022s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 4/16, index chunk 1/4. Building reference seed array... [0.02s] Building query seed array... [0.019s] Computing hash join... [0.004s] Masking low complexity seeds... [0.003s] Searching alignments... [0.025s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 4/16, index chunk 2/4. Building reference seed array... [0.019s] Building query seed array... [0.015s] Computing hash join... [0.004s] Masking low complexity seeds... [0.004s] Searching alignments... [0.023s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 4/16, index chunk 3/4. Building reference seed array... [0.018s] Building query seed array... [0.01s] Computing hash join... [0.004s] Masking low complexity seeds... [0.003s] Searching alignments... [0.024s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 4/16, index chunk 4/4. Building reference seed array... [0.018s] Building query seed array... [0.02s] Computing hash join... [0.004s] Masking low complexity seeds... [0.003s] Searching alignments... [0.024s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 5/16, index chunk 1/4. Building reference seed array... [0.026s] Building query seed array... [0.018s] Computing hash join... [0.005s] Masking low complexity seeds... [0.004s] Searching alignments... [0.028s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 5/16, index chunk 2/4. Building reference seed array... [0.015s] Building query seed array... [0.019s] Computing hash join... [0.005s] Masking low complexity seeds... [0.004s] Searching alignments... [0.018s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 5/16, index chunk 3/4. Building reference seed array... [0.024s] Building query seed array... [0.023s] Computing hash join... [0.003s] Masking low complexity seeds... [0.004s] Searching alignments... [0.022s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 5/16, index chunk 4/4. Building reference seed array... [0.03s] Building query seed array... [0.01s] Computing hash join... [0.004s] Masking low complexity seeds... [0.003s] Searching alignments... [0.017s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 6/16, index chunk 1/4. Building reference seed array... [0.01s] Building query seed array... [0.01s] Computing hash join... [0.004s] Masking low complexity seeds... [0.004s] Searching alignments... [0.017s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 6/16, index chunk 2/4. Building reference seed array... [0.012s] Building query seed array... [0.016s] Computing hash join... [0.005s] Masking low complexity seeds... [0.004s] Searching alignments... [0.025s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 6/16, index chunk 3/4. Building reference seed array... [0.009s] Building query seed array... [0.013s] Computing hash join... [0.004s] Masking low complexity seeds... [0.004s] Searching alignments... [0.022s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 6/16, index chunk 4/4. Building reference seed array... [0.034s] Building query seed array... [0.018s] Computing hash join... [0.004s] Masking low complexity seeds... [0.004s] Searching alignments... [0.023s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 7/16, index chunk 1/4. Building reference seed array... [0.011s] Building query seed array... [0.011s] Computing hash join... [0.003s] Masking low complexity seeds... [0.003s] Searching alignments... [0.023s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 7/16, index chunk 2/4. Building reference seed array... [0.015s] Building query seed array... [0.016s] Computing hash join... [0.005s] Masking low complexity seeds... [0.003s] Searching alignments... [0.02s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 7/16, index chunk 3/4. Building reference seed array... [0.015s] Building query seed array... [0.022s] Computing hash join... [0.005s] Masking low complexity seeds... [0.004s] Searching alignments... [0.025s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 7/16, index chunk 4/4. Building reference seed array... [0.015s] Building query seed array... [0.022s] Computing hash join... [0.005s] Masking low complexity seeds... [0.003s] Searching alignments... [0.023s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 8/16, index chunk 1/4. Building reference seed array... [0.021s] Building query seed array... [0.013s] Computing hash join... [0.004s] Masking low complexity seeds... [0.003s] Searching alignments... [0.024s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 8/16, index chunk 2/4. Building reference seed array... [0.026s] Building query seed array... [0.027s] Computing hash join... [0.004s] Masking low complexity seeds... [0.004s] Searching alignments... [0.026s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 8/16, index chunk 3/4. Building reference seed array... [0.012s] Building query seed array... [0.023s] Computing hash join... [0.004s] Masking low complexity seeds... [0.004s] Searching alignments... [0.025s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 8/16, index chunk 4/4. Building reference seed array... [0.017s] Building query seed array... [0.015s] Computing hash join... [0.005s] Masking low complexity seeds... [0.004s] Searching alignments... [0.025s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 9/16, index chunk 1/4. Building reference seed array... [0.017s] Building query seed array... [0.013s] Computing hash join... [0.005s] Masking low complexity seeds... [0.004s] Searching alignments... [0.026s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 9/16, index chunk 2/4. Building reference seed array... [0.018s] Building query seed array... [0.032s] Computing hash join... [0.004s] Masking low complexity seeds... [0.003s] Searching alignments... [0.024s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 9/16, index chunk 3/4. Building reference seed array... [0.009s] Building query seed array... [0.01s] Computing hash join... [0.005s] Masking low complexity seeds... [0.003s] Searching alignments... [0.022s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 9/16, index chunk 4/4. Building reference seed array... [0.027s] Building query seed array... [0.013s] Computing hash join... [0.004s] Masking low complexity seeds... [0.003s] Searching alignments... [0.019s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 10/16, index chunk 1/4. Building reference seed array... [0.023s] Building query seed array... [0.022s] Computing hash join... [0.004s] Masking low complexity seeds... [0.003s] Searching alignments... [0.019s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 10/16, index chunk 2/4. Building reference seed array... [0.009s] Building query seed array... [0.022s] Computing hash join... [0.004s] Masking low complexity seeds... [0.005s] Searching alignments... [0.026s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 10/16, index chunk 3/4. Building reference seed array... [0.011s] Building query seed array... [0.029s] Computing hash join... [0.008s] Masking low complexity seeds... [0.003s] Searching alignments... [0.023s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 10/16, index chunk 4/4. Building reference seed array... [0.029s] Building query seed array... [0.01s] Computing hash join... [0.003s] Masking low complexity seeds... [0.003s] Searching alignments... [0.021s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 11/16, index chunk 1/4. Building reference seed array... [0.009s] Building query seed array... [0.013s] Computing hash join... [0.004s] Masking low complexity seeds... [0.004s] Searching alignments... [0.024s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 11/16, index chunk 2/4. Building reference seed array... [0.031s] Building query seed array... [0.013s] Computing hash join... [0.003s] Masking low complexity seeds... [0.003s] Searching alignments... [0.02s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 11/16, index chunk 3/4. Building reference seed array... [0.01s] Building query seed array... [0.01s] Computing hash join... [0.003s] Masking low complexity seeds... [0.003s] Searching alignments... [0.021s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 11/16, index chunk 4/4. Building reference seed array... [0.01s] Building query seed array... [0.013s] Computing hash join... [0.004s] Masking low complexity seeds... [0.003s] Searching alignments... [0.023s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 12/16, index chunk 1/4. Building reference seed array... [0.03s] Building query seed array... [0.016s] Computing hash join... [0.004s] Masking low complexity seeds... [0.003s] Searching alignments... [0.021s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 12/16, index chunk 2/4. Building reference seed array... [0.023s] Building query seed array... [0.029s] Computing hash join... [0.004s] Masking low complexity seeds... [0.003s] Searching alignments... [0.022s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 12/16, index chunk 3/4. Building reference seed array... [0.012s] Building query seed array... [0.016s] Computing hash join... [0.004s] Masking low complexity seeds... [0.004s] Searching alignments... [0.017s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 12/16, index chunk 4/4. Building reference seed array... [0.028s] Building query seed array... [0.025s] Computing hash join... [0.005s] Masking low complexity seeds... [0.003s] Searching alignments... [0.02s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 13/16, index chunk 1/4. Building reference seed array... [0.012s] Building query seed array... [0.012s] Computing hash join... [0.004s] Masking low complexity seeds... [0.003s] Searching alignments... [0.018s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 13/16, index chunk 2/4. Building reference seed array... [0.01s] Building query seed array... [0.01s] Computing hash join... [0.003s] Masking low complexity seeds... [0.004s] Searching alignments... [0.021s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 13/16, index chunk 3/4. Building reference seed array... [0.029s] Building query seed array... [0.016s] Computing hash join... [0.005s] Masking low complexity seeds... [0.004s] Searching alignments... [0.022s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 13/16, index chunk 4/4. Building reference seed array... [0.026s] Building query seed array... [0.025s] Computing hash join... [0.005s] Masking low complexity seeds... [0.004s] Searching alignments... [0.023s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 14/16, index chunk 1/4. Building reference seed array... [0.02s] Building query seed array... [0.026s] Computing hash join... [0.005s] Masking low complexity seeds... [0.004s] Searching alignments... [0.026s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 14/16, index chunk 2/4. Building reference seed array... [0.023s] Building query seed array... [0.01s] Computing hash join... [0.005s] Masking low complexity seeds... [0.003s] Searching alignments... [0.025s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 14/16, index chunk 3/4. Building reference seed array... [0.018s] Building query seed array... [0.011s] Computing hash join... [0.005s] Masking low complexity seeds... [0.004s] Searching alignments... [0.025s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 14/16, index chunk 4/4. Building reference seed array... [0.018s] Building query seed array... [0.023s] Computing hash join... [0.007s] Masking low complexity seeds... [0.006s] Searching alignments... [0.022s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 15/16, index chunk 1/4. Building reference seed array... [0.01s] Building query seed array... [0.02s] Computing hash join... [0.006s] Masking low complexity seeds... [0.005s] Searching alignments... [0.025s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 15/16, index chunk 2/4. Building reference seed array... [0.026s] Building query seed array... [0.022s] Computing hash join... [0.006s] Masking low complexity seeds... [0.003s] Searching alignments... [0.029s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 15/16, index chunk 3/4. Building reference seed array... [0.015s] Building query seed array... [0.011s] Computing hash join... [0.006s] Masking low complexity seeds... [0.004s] Searching alignments... [0.023s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 15/16, index chunk 4/4. Building reference seed array... [0.034s] Building query seed array... [0.022s] Computing hash join... [0.006s] Masking low complexity seeds... [0.005s] Searching alignments... [0.03s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 16/16, index chunk 1/4. Building reference seed array... [0.02s] Building query seed array... [0.01s] Computing hash join... [0.006s] Masking low complexity seeds... [0.005s] Searching alignments... [0.025s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 16/16, index chunk 2/4. Building reference seed array... [0.025s] Building query seed array... [0.01s] Computing hash join... [0.006s] Masking low complexity seeds... [0.005s] Searching alignments... [0.024s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 16/16, index chunk 3/4. Building reference seed array... [0.017s] Building query seed array... [0.023s] Computing hash join... [0.004s] Masking low complexity seeds... [0.004s] Searching alignments... [0.028s] Deallocating memory... [0s] Processing query block 1, reference block 1/1, shape 16/16, index chunk 4/4. Building reference seed array... [0.022s] Building query seed array... [0.02s] Computing hash join... [0.006s] Masking low complexity seeds... [0.004s] Searching alignments... [0.028s] Deallocating memory... [0s] Deallocating buffers... [0s] Clearing query masking... [0.002s] Computing alignments... [0.754s] Deallocating reference... [0s] Loading reference sequences... [0s] Deallocating buffers... [0s] Deallocating queries... [0s] Loading query sequences... [0s] Closing the input file... [0s] Closing the output file... [0s] Closing the database... [0s] Cleaning up... [0s] Total time = 5.731s Reported 21'255 pairwise alignments, 21'255 HSPs. 21'255 queries aligned. [Fri Oct 9 09:26:12 PDT 2026] 9306 one-to-one orthologs -> output/14-meth-compare/orthologs/Och_Olur_rbh.tsv