gene_id symbol product lean_mean siscowet_mean meth_diff n_lean n_siscowet n_cpgs_lean n_cpgs_siscowet pvalue qvalue significant significant_fdr direction gene-LOC120017932_1 34.07 58.7 24.63 4 4 54 54 0.02857142857142857 0.7251923720307795 True False hyper_siscowet gene-LOC120019356 LOC120019356 gastrula zinc finger protein XlCGF17.1-like 89.97 74.88 -15.09 4 4 329 316 0.02857142857142857 0.7251923720307795 True False hypo_siscowet gene-LOC120024970 LOC120024970 tropomyosin alpha-1 chain 43.98 73.81 29.83 4 4 184 204 0.02857142857142857 0.7251923720307795 True False hyper_siscowet gene-LOC120029185 LOC120029185 multiple epidermal growth factor-like domains protein 6 75.47 91.13 15.65 4 4 276 906 0.02857142857142857 0.7251923720307795 True False hyper_siscowet gene-LOC120029452 LOC120029452 histone acetyltransferase KAT6B-like 94.65 75.44 -19.2 4 4 348 778 0.02857142857142857 0.7251923720307795 True False hypo_siscowet gene-LOC120030840 LOC120030840 serine protease hepsin-like 61.51 86.23 24.72 4 4 81 121 0.02857142857142857 0.7251923720307795 True False hyper_siscowet gene-LOC120032833 LOC120032833 SH3 and PX domain-containing protein 2A-like 49.83 87.95 38.12 4 4 114 985 0.02857142857142857 0.7251923720307795 True False hyper_siscowet gene-LOC120033391 LOC120033391 microtubule-associated protein 2-like 89.88 66.29 -23.59 4 4 463 472 0.02857142857142857 0.7251923720307795 True False hypo_siscowet gene-LOC120033680 LOC120033680 uncharacterized LOC120033680 95.37 58.46 -36.91 4 4 15 59 0.02857142857142857 0.7251923720307795 True False hypo_siscowet gene-LOC120034001 LOC120034001 protein phosphatase 1 regulatory subunit 27-like 90.25 70.24 -20.01 4 4 172 273 0.02857142857142857 0.7251923720307795 True False hypo_siscowet gene-LOC120034136 LOC120034136 alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial-like 60.38 85.87 25.49 4 4 146 133 0.02857142857142857 0.7251923720307795 True False hyper_siscowet gene-LOC120034155 LOC120034155 monocyte to macrophage differentiation factor 32.27 81.91 49.64 4 4 124 207 0.02857142857142857 0.7251923720307795 True False hyper_siscowet gene-LOC120035360 LOC120035360 scavenger receptor cysteine-rich type 1 protein M130-like 67.97 92.4 24.42 4 4 10 4 0.02857142857142857 0.7251923720307795 True False hyper_siscowet gene-LOC120035419 LOC120035419 5S ribosomal RNA 52.11 22.16 -29.95 4 4 8 8 0.02857142857142857 0.7251923720307795 True False hypo_siscowet gene-LOC120035963 LOC120035963 zinc finger protein 501-like 53.08 77.97 24.89 4 4 198 197 0.02857142857142857 0.7251923720307795 True False hyper_siscowet gene-LOC120036468_2 86.24 70.15 -16.08 4 4 172 191 0.02857142857142857 0.7251923720307795 True False hypo_siscowet gene-LOC120036468_5 60.05 89.23 29.18 4 4 191 81 0.02857142857142857 0.7251923720307795 True False hyper_siscowet gene-LOC120036806 LOC120036806 5S ribosomal RNA 38.22 96.61 58.39 4 4 7 7 0.02857142857142857 0.7251923720307795 True False hyper_siscowet gene-LOC120037149 LOC120037149 histone H1-like 61.45 36.25 -25.2 4 4 50 50 0.02857142857142857 0.7251923720307795 True False hypo_siscowet gene-LOC120037731 LOC120037731 zinc finger protein 420-like 17.49 35.03 17.54 4 4 5 11 0.02857142857142857 0.7251923720307795 True False hyper_siscowet gene-LOC120039155 LOC120039155 uncharacterized LOC120039155 46.87 79.89 33.02 4 4 30 35 0.02857142857142857 0.7251923720307795 True False hyper_siscowet gene-LOC120039201 LOC120039201 uncharacterized LOC120039201 53.98 37.77 -16.21 4 4 66 61 0.02857142857142857 0.7251923720307795 True False hypo_siscowet gene-LOC120039209 LOC120039209 zinc finger protein OZF-like 92.11 67.61 -24.5 4 4 105 373 0.02857142857142857 0.7251923720307795 True False hypo_siscowet gene-LOC120039214 LOC120039214 uncharacterized LOC120039214 77.71 95.19 17.48 4 4 262 9 0.02857142857142857 0.7251923720307795 True False hyper_siscowet gene-LOC120039231 LOC120039231 uncharacterized LOC120039231 55.78 79.98 24.21 4 4 154 236 0.02857142857142857 0.7251923720307795 True False hyper_siscowet gene-LOC120039343 LOC120039343 gastrula zinc finger protein XlCGF17.1-like 43.97 91.85 47.88 4 4 8 303 0.02857142857142857 0.7251923720307795 True False hyper_siscowet gene-LOC120039613_1 41.45 61.16 19.72 4 4 51 93 0.02857142857142857 0.7251923720307795 True False hyper_siscowet gene-LOC120039779 LOC120039779 zinc finger protein 501-like 51.84 82.98 31.13 4 4 8 453 0.02857142857142857 0.7251923720307795 True False hyper_siscowet gene-LOC120039782 LOC120039782 zinc finger protein 850-like 87.81 71.8 -16.0 4 4 19 24 0.02857142857142857 0.7251923720307795 True False hypo_siscowet gene-LOC120040804 LOC120040804 uncharacterized LOC120040804 9.18 53.96 44.78 4 4 39 74 0.02857142857142857 0.7251923720307795 True False hyper_siscowet gene-LOC120040994 LOC120040994 tripartite motif-containing protein 16-like 85.16 68.19 -16.97 4 4 106 58 0.02857142857142857 0.7251923720307795 True False hypo_siscowet gene-LOC120041006 LOC120041006 tripartite motif-containing protein 34-like 66.22 92.94 26.73 4 4 13 7 0.02857142857142857 0.7251923720307795 True False hyper_siscowet gene-LOC120041020 LOC120041020 tripartite motif-containing protein 16-like 90.32 67.23 -23.09 4 4 340 78 0.02857142857142857 0.7251923720307795 True False hypo_siscowet gene-LOC120041406 LOC120041406 zinc finger protein 2-like 69.28 46.0 -23.28 4 4 113 90 0.02857142857142857 0.7251923720307795 True False hypo_siscowet gene-LOC120041810 LOC120041810 U1 spliceosomal RNA 96.17 1.1 -95.07 4 4 8 7 0.02857142857142857 0.7251923720307795 True False hypo_siscowet gene-LOC120042072 LOC120042072 transport and Golgi organization protein 1 homolog 58.57 28.12 -30.45 4 4 68 63 0.02857142857142857 0.7251923720307795 True False hypo_siscowet gene-LOC120044697 LOC120044697 ethanolamine-phosphate cytidylyltransferase-like 86.03 51.25 -34.78 4 4 165 343 0.02857142857142857 0.7251923720307795 True False hypo_siscowet gene-LOC120044866 LOC120044866 nuclear GTPase SLIP-GC-like 53.6 87.13 33.52 4 4 248 501 0.02857142857142857 0.7251923720307795 True False hyper_siscowet gene-LOC120045278 LOC120045278 5S ribosomal RNA 47.49 94.48 46.99 4 4 8 7 0.02857142857142857 0.7251923720307795 True False hyper_siscowet gene-LOC120046630 LOC120046630 voltage-dependent anion-selective channel protein 2-like 96.38 64.49 -31.88 4 4 96 195 0.02857142857142857 0.7251923720307795 True False hypo_siscowet gene-LOC120049232 LOC120049232 cGMP-inhibited 3',5'-cyclic phosphodiesterase B-like 61.7 90.9 29.2 4 4 830 884 0.02857142857142857 0.7251923720307795 True False hyper_siscowet gene-LOC120050553 LOC120050553 acetyl-CoA carboxylase-like 74.5 93.72 19.22 4 4 655 461 0.02857142857142857 0.7251923720307795 True False hyper_siscowet gene-LOC120051268 LOC120051268 tyrosine-protein phosphatase non-receptor type 4-like 49.06 84.98 35.92 4 4 68 629 0.02857142857142857 0.7251923720307795 True False hyper_siscowet gene-LOC120051357 LOC120051357 phospholipid phosphatase 2-like 73.46 52.41 -21.05 4 4 136 174 0.02857142857142857 0.7251923720307795 True False hypo_siscowet gene-LOC120052184 LOC120052184 uncharacterized LOC120052184 91.58 6.24 -85.33 4 4 58 165 0.02857142857142857 0.7251923720307795 True False hypo_siscowet gene-LOC120052442 LOC120052442 RNA polymerase II elongation factor ELL-like 61.84 89.19 27.35 4 4 311 643 0.02857142857142857 0.7251923720307795 True False hyper_siscowet gene-LOC120052924 LOC120052924 zinc finger protein 606-like 67.16 85.75 18.59 4 4 865 1421 0.02857142857142857 0.7251923720307795 True False hyper_siscowet gene-LOC120052940 LOC120052940 zinc finger protein-like 62.62 79.84 17.22 4 4 763 1649 0.02857142857142857 0.7251923720307795 True False hyper_siscowet gene-LOC120052962 LOC120052962 transcription factor Ken-like 66.64 86.33 19.69 4 4 1486 2276 0.02857142857142857 0.7251923720307795 True False hyper_siscowet gene-LOC120053068 LOC120053068 uncharacterized LOC120053068 66.86 48.4 -18.46 4 4 57 39 0.02857142857142857 0.7251923720307795 True False hypo_siscowet gene-LOC120057139 LOC120057139 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1-like 51.54 93.15 41.6 4 4 250 139 0.02857142857142857 0.7251923720307795 True False hyper_siscowet gene-LOC120059971 LOC120059971 ryanodine receptor 3-like 59.08 88.52 29.44 4 4 236 676 0.02857142857142857 0.7251923720307795 True False hyper_siscowet gene-LOC120060189 LOC120060189 disintegrin and metalloproteinase domain-containing protein 17-like 63.11 90.12 27.01 4 4 198 551 0.02857142857142857 0.7251923720307795 True False hyper_siscowet gene-LOC120064695 LOC120064695 protein PHTF2-like 78.05 94.25 16.21 4 4 120 137 0.02857142857142857 0.7251923720307795 True False hyper_siscowet gene-cacul1 cacul1 CDK2 associated cullin domain 1 93.21 39.84 -53.37 4 4 71 210 0.02857142857142857 0.7251923720307795 True False hypo_siscowet gene-irak3 irak3 interleukin-1 receptor-associated kinase 3 79.51 48.12 -31.39 4 4 313 305 0.02857142857142857 0.7251923720307795 True False hypo_siscowet gene-tmbim4 tmbim4 transmembrane BAX inhibitor motif containing 4 41.47 80.68 39.21 4 4 103 210 0.02857142857142857 0.7251923720307795 True False hyper_siscowet gene-trnam-cau-3_23 94.75 79.04 -15.71 4 4 5 5 0.02857142857142857 0.7251923720307795 True False hypo_siscowet gene-LOC120042985 LOC120042985 U1 spliceosomal RNA 97.79 1.28 -96.51 4 4 8 9 0.029401048190339642 0.7251923720307795 True False hypo_siscowet gene-trnaq-cug-55 trnaq-cug tRNA-Gln 88.82 1.69 -87.12 3 4 3 3 0.04359664488554136 0.7251923720307795 True False hypo_siscowet gene-LOC120036592 LOC120036592 non-structural maintenance of chromosomes element 1 homolog 38.46 74.41 35.94 3 4 10 140 0.04974599072150299 0.7251923720307795 True False hyper_siscowet gene-trnav-cac-14_13 79.51 96.1 16.59 3 4 6 6 0.04974599072150299 0.7251923720307795 True False hyper_siscowet gene-ttyh2l ttyh2l tweety homolog 2, like 0.13 78.33 78.2 3 4 12 377 0.04974599072150299 0.7251923720307795 True False hyper_siscowet