GeneID logFC logCPM F PValue FDR Accession Isoform E-value ProteinN GO_BP GO_CC GO_MF GO Status Organism 1 TRINITY_DN173970_c0_g1 19.7709273 14.04275312 103.1232144 7.15E-12 7.09E-10 Q54IP4 TRINITY_DN173970_c0_g1_i1 1.90E-06 Dual specificity protein kinase shkB (EC 2.7.11.1) (SH2 domain-containing protein 2) (SH2 domain-containing protein B) membrane [GO:0016020] ATP binding [GO:0005524]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713] GO:0004674; GO:0004713; GO:0005524; GO:0016020 reviewed Dictyostelium discoideum (Slime mold) 2 TRINITY_DN2119_c0_g1 9.513758938 6.962782931 12.52155868 0.00141148 0.021271833 Q54HM6 TRINITY_DN2119_c0_g1_i1 1.00E-08 "Cytochrome c oxidase assembly protein COX11, mitochondrial" aerobic respiration [GO:0009060]; protein-containing complex assembly [GO:0065003] integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739] copper ion binding [GO:0005507] GO:0005507; GO:0005739; GO:0005743; GO:0009060; GO:0016021; GO:0065003 reviewed Dictyostelium discoideum (Slime mold) 3 TRINITY_DN22073_c0_g1 7.733246973 6.630983065 10.80686807 0.002704897 0.036473403 Q979Z2 TRINITY_DN22073_c0_g1_i1 1.10E-07 Calcium-gated potassium channel TvoK integral component of membrane [GO:0016021]; plasma membrane [GO:0005886] metal ion binding [GO:0046872]; potassium channel activity [GO:0005267] GO:0005267; GO:0005886; GO:0016021; GO:0046872 reviewed Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1) 4 TRINITY_DN226644_c0_g1 17.21809245 10.67100942 64.03393449 4.60E-09 1.59E-07 Q29RV1 TRINITY_DN226644_c0_g1_i1 2.00E-10 Protein disulfide-isomerase A4 (EC 5.3.4.1) cell redox homeostasis [GO:0045454]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976] cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; melanosome [GO:0042470] protein disulfide isomerase activity [GO:0003756] GO:0003756; GO:0005783; GO:0005788; GO:0006457; GO:0009986; GO:0034976; GO:0042470; GO:0045454 reviewed Bos taurus (Bovine) 5 TRINITY_DN227396_c0_g1 -9.766477453 7.100089474 10.95723076 0.00248088 0.033808586 Q7LHG5 TRINITY_DN227396_c0_g1_i1 1.80E-07 Transposon Ty3-I Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-2 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p52 (IN); Integrase p49 (IN)] "DNA integration [GO:0015074]; DNA recombination [GO:0006310]; transposition, RNA-mediated [GO:0032197]" cytoplasm [GO:0005737]; nucleus [GO:0005634]; retrotransposon nucleocapsid [GO:0000943] aspartic-type endopeptidase activity [GO:0004190]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; peptidase activity [GO:0008233]; ribonuclease activity [GO:0004540]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0008233; GO:0008270; GO:0015074; GO:0032197 reviewed Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 6 TRINITY_DN233011_c0_g1 19.0641312 14.00249983 108.5450111 3.66E-12 6.02E-10 Q55E58 TRINITY_DN233011_c0_g1_i1 3.20E-21 Probable serine/threonine-protein kinase pats1 (EC 2.7.11.1) (Protein associated with the transduction of signal 1) cheating during chimeric sorocarp development [GO:0099139]; mitotic cytokinesis [GO:0000281]; protein dephosphorylation [GO:0006470] actomyosin [GO:0042641] ATP binding [GO:0005524]; GTP binding [GO:0005525]; phosphoprotein phosphatase activity [GO:0004721]; protein serine/threonine kinase activity [GO:0004674] GO:0000281; GO:0004674; GO:0004721; GO:0005524; GO:0005525; GO:0006470; GO:0042641; GO:0099139 reviewed Dictyostelium discoideum (Slime mold) 7 TRINITY_DN251134_c0_g1 18.85656658 13.8306835 86.20600146 6.95E-11 3.56E-09 Q99LT0 TRINITY_DN251134_c0_g1_i1 4.50E-07 Protein dpy-30 homolog (Dpy-30-like protein) (Dpy-30L) endosomal transport [GO:0016197]; histone H3-K4 methylation [GO:0051568] Golgi apparatus [GO:0005794]; histone methyltransferase complex [GO:0035097]; MLL3/4 complex [GO:0044666]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Set1C/COMPASS complex [GO:0048188]; trans-Golgi network [GO:0005802] identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803] GO:0005634; GO:0005654; GO:0005794; GO:0005802; GO:0016197; GO:0035097; GO:0042802; GO:0042803; GO:0044666; GO:0048188; GO:0051568 reviewed Mus musculus (Mouse) 8 TRINITY_DN251134_c1_g1 9.595183118 6.98803541 12.74235263 0.001301176 0.020326902 Q9P0X4 TRINITY_DN251134_c1_g1_i1 2.20E-09 Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage-gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3) calcium ion import [GO:0070509]; flagellated sperm motility [GO:0030317]; membrane depolarization during action potential [GO:0086010]; neuronal action potential [GO:0019228]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; regulation of ion transmembrane transport [GO:0034765]; signal transduction [GO:0007165]; sleep [GO:0030431] plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891] low voltage-gated calcium channel activity [GO:0008332]; voltage-gated calcium channel activity [GO:0005245] GO:0005245; GO:0005886; GO:0005891; GO:0007165; GO:0008332; GO:0019228; GO:0030317; GO:0030431; GO:0034765; GO:0045956; GO:0070509; GO:0086010 reviewed Homo sapiens (Human) 9 TRINITY_DN251191_c0_g1 10.16112929 7.118224301 14.65042771 0.000657533 0.011382423 P65850 TRINITY_DN251191_c0_g1_i1 5.00E-07 tRNA pseudouridine synthase A (EC 5.4.99.12) (tRNA pseudouridine(38-40) synthase) (tRNA pseudouridylate synthase I) (tRNA-uridine isomerase I) tRNA pseudouridine synthesis [GO:0031119] RNA binding [GO:0003723]; tRNA pseudouridine synthase activity [GO:0106029] GO:0003723; GO:0031119; GO:0106029 reviewed Streptococcus pyogenes serotype M1 10 TRINITY_DN251191_c0_g2 18.47912781 10.49183619 62.82066022 1.15E-08 3.89E-07 Q8Y457 TRINITY_DN251191_c0_g2_i1 6.20E-17 tRNA pseudouridine synthase A (EC 5.4.99.12) (tRNA pseudouridine(38-40) synthase) (tRNA pseudouridylate synthase I) (tRNA-uridine isomerase I) tRNA pseudouridine synthesis [GO:0031119] pseudouridine synthase activity [GO:0009982]; RNA binding [GO:0003723]; tRNA pseudouridine synthase activity [GO:0106029] GO:0003723; GO:0009982; GO:0031119; GO:0106029 reviewed Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) 11 TRINITY_DN255273_c0_g1 19.56437005 13.25833804 107.9511823 3.94E-12 6.02E-10 Q8IXJ6 TRINITY_DN255273_c0_g1_i1 7.40E-11 NAD-dependent protein deacetylase sirtuin-2 (EC 3.5.1.-) (Regulatory protein SIR2 homolog 2) (SIR2-like protein 2) "autophagy [GO:0006914]; cell division [GO:0051301]; cellular lipid catabolic process [GO:0044242]; cellular response to caloric restriction [GO:0061433]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hypoxia [GO:0071456]; cellular response to molecule of bacterial origin [GO:0071219]; cellular response to oxidative stress [GO:0034599]; chromatin silencing [GO:0006342]; chromatin silencing at rDNA [GO:0000183]; chromatin silencing at telomere [GO:0006348]; gene silencing [GO:0016458]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; histone deacetylation [GO:0016575]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; innate immune response [GO:0045087]; meiotic cell cycle [GO:0051321]; myelination in peripheral nervous system [GO:0022011]; negative regulation of autophagy [GO:0010507]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of defense response to bacterium [GO:1900425]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of oligodendrocyte progenitor proliferation [GO:0070446]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of striated muscle tissue development [GO:0045843]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061428]; peptidyl-lysine deacetylation [GO:0034983]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of attachment of spindle microtubules to kinetochore [GO:0051987]; positive regulation of cell division [GO:0051781]; positive regulation of DNA binding [GO:0043388]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of meiotic nuclear division [GO:0045836]; positive regulation of oocyte maturation [GO:1900195]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia [GO:2000777]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ADP-ribosylation [GO:0006471]; protein deacetylation [GO:0006476]; protein kinase B signaling [GO:0043491]; regulation of cell cycle [GO:0051726]; regulation of exit from mitosis [GO:0007096]; regulation of myelination [GO:0031641]; regulation of phosphorylation [GO:0042325]; response to redox state [GO:0051775]; substantia nigra development [GO:0021762]; tubulin deacetylation [GO:0090042]" "centriole [GO:0005814]; centrosome [GO:0005813]; chromatin silencing complex [GO:0005677]; chromosome [GO:0005694]; chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glial cell projection [GO:0097386]; growth cone [GO:0030426]; juxtaparanode region of axon [GO:0044224]; lateral loop [GO:0043219]; meiotic spindle [GO:0072687]; microtubule [GO:0005874]; midbody [GO:0030496]; mitochondrion [GO:0005739]; mitotic spindle [GO:0072686]; myelin sheath [GO:0043209]; nuclear heterochromatin [GO:0005720]; nucleolus [GO:0005730]; nucleus [GO:0005634]; paranodal junction [GO:0033010]; paranode region of axon [GO:0033270]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; Schmidt-Lanterman incisure [GO:0043220]; spindle [GO:0005819]" chromatin binding [GO:0003682]; histone acetyltransferase binding [GO:0035035]; histone deacetylase activity [GO:0004407]; histone deacetylase binding [GO:0042826]; NAD+ binding [GO:0070403]; NAD-dependent histone deacetylase activity [GO:0017136]; NAD-dependent histone deacetylase activity (H4-K16 specific) [GO:0046970]; NAD-dependent protein deacetylase activity [GO:0034979]; protein deacetylase activity [GO:0033558]; transcription factor binding [GO:0008134]; tubulin deacetylase activity [GO:0042903]; ubiquitin binding [GO:0043130]; zinc ion binding [GO:0008270] GO:0000122; GO:0000183; GO:0000781; GO:0003682; GO:0004407; GO:0005634; GO:0005677; GO:0005694; GO:0005720; GO:0005730; GO:0005737; GO:0005739; GO:0005813; GO:0005814; GO:0005819; GO:0005829; GO:0005874; GO:0005886; GO:0006342; GO:0006348; GO:0006471; GO:0006476; GO:0006914; GO:0007096; GO:0008134; GO:0008270; GO:0008285; GO:0010507; GO:0010801; GO:0014065; GO:0016458; GO:0016575; GO:0017136; GO:0021762; GO:0022011; GO:0030426; GO:0030496; GO:0031641; GO:0032436; GO:0033010; GO:0033270; GO:0033558; GO:0034599; GO:0034979; GO:0034983; GO:0035035; GO:0035729; GO:0042177; GO:0042325; GO:0042826; GO:0042903; GO:0043130; GO:0043161; GO:0043204; GO:0043209; GO:0043219; GO:0043220; GO:0043388; GO:0043491; GO:0044224; GO:0044242; GO:0045087; GO:0045599; GO:0045836; GO:0045843; GO:0045892; GO:0045944; GO:0046970; GO:0048012; GO:0048471; GO:0051301; GO:0051321; GO:0051726; GO:0051775; GO:0051781; GO:0051987; GO:0061428; GO:0061433; GO:0070403; GO:0070446; GO:0070932; GO:0070933; GO:0071219; GO:0071456; GO:0071872; GO:0072686; GO:0072687; GO:0090042; GO:0097386; GO:1900119; GO:1900195; GO:1900226; GO:1900425; GO:2000378; GO:2000777 reviewed Homo sapiens (Human) 12 TRINITY_DN255903_c0_g1 16.41968284 9.59453111 39.20731433 8.69E-07 2.53E-05 Q5BJJ7 TRINITY_DN255903_c0_g1_i1 1.50E-08 Protein BCCIP homolog cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; establishment of mitotic spindle orientation [GO:0000132]; microtubule anchoring [GO:0034453]; microtubule cytoskeleton organization [GO:0000226]; mitotic spindle assembly [GO:0090307]; mitotic spindle organization [GO:0007052]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079] centriole [GO:0005814]; centrosome [GO:0005813]; mitotic spindle pole [GO:0097431]; nucleus [GO:0005634] kinase regulator activity [GO:0019207]; tubulin binding [GO:0015631] GO:0000079; GO:0000132; GO:0000226; GO:0005634; GO:0005813; GO:0005814; GO:0006281; GO:0006974; GO:0007052; GO:0015631; GO:0019207; GO:0034453; GO:0090307; GO:0097431 reviewed Danio rerio (Zebrafish) (Brachydanio rerio) 13 TRINITY_DN256449_c0_g1 16.09956622 9.258301558 37.10442962 1.37E-06 3.91E-05 Q29350 TRINITY_DN256449_c0_g1_i1 2.00E-08 Splicing factor U2AF 35 kDa subunit (U2 auxiliary factor 35 kDa subunit) (U2 snRNP auxiliary factor small subunit) (Fragment) "mRNA splicing, via spliceosome [GO:0000398]" nuclear speck [GO:0016607]; spliceosomal complex [GO:0005681]; U2AF [GO:0089701] metal ion binding [GO:0046872]; pre-mRNA 3'-splice site binding [GO:0030628] GO:0000398; GO:0005681; GO:0016607; GO:0030628; GO:0046872; GO:0089701 reviewed Sus scrofa (Pig) 14 TRINITY_DN259150_c0_g1 -9.072361637 7.231336227 10.38719778 0.003106981 0.04061268 Q6AYG5 TRINITY_DN259150_c0_g1_i1 2.00E-27 Ethylmalonyl-CoA decarboxylase (EC 4.1.1.94) (Enoyl-CoA hydratase domain-containing protein 1) (Methylmalonyl-CoA decarboxylase) (MMCD) (EC 7.2.4.3) fatty acid beta-oxidation [GO:0006635] cytosol [GO:0005829] carboxy-lyase activity [GO:0016831]; enoyl-CoA hydratase activity [GO:0004300] GO:0004300; GO:0005829; GO:0006635; GO:0016831 reviewed Rattus norvegicus (Rat) 15 TRINITY_DN271642_c0_g1 19.9376128 14.06191571 107.361798 4.23E-12 6.02E-10 P35728 TRINITY_DN271642_c0_g1_i1 2.00E-14 Protein MPE1 mRNA polyadenylation [GO:0006378]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; protein ubiquitination [GO:0016567] cytosol [GO:0005829]; mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nucleus [GO:0005634] pre-mRNA binding [GO:0036002]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] GO:0005634; GO:0005829; GO:0005847; GO:0006378; GO:0008270; GO:0016567; GO:0036002; GO:0061630; GO:0098789 reviewed Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 16 TRINITY_DN271666_c1_g1 18.02592667 10.14568525 53.15141814 5.79E-08 1.81E-06 O42881 TRINITY_DN271666_c1_g1_i1 1.20E-07 Acyl-protein thioesterase 1 (EC 3.1.2.-) fatty acid metabolic process [GO:0006631]; protein depalmitoylation [GO:0002084] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634] carboxylic ester hydrolase activity [GO:0052689]; palmitoyl-(protein) hydrolase activity [GO:0008474] GO:0002084; GO:0005634; GO:0005737; GO:0005829; GO:0006631; GO:0008474; GO:0052689 reviewed Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) 17 TRINITY_DN274712_c0_g1 19.48917008 14.44543729 85.85115813 7.32E-11 3.60E-09 Q6P7K0 TRINITY_DN274712_c0_g1_i1 5.50E-09 Carboxymethylenebutenolidase homolog (EC 3.1.-.-) cytosol [GO:0005829] hydrolase activity [GO:0016787] GO:0005829; GO:0016787 reviewed Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) 18 TRINITY_DN274805_c0_g2 18.46155069 14.38921015 101.942186 8.30E-12 7.09E-10 P14318 TRINITY_DN274805_c0_g2_i1 7.90E-17 Muscle-specific protein 20 myoblast fusion [GO:0007520]; regulation of myoblast fusion [GO:1901739] cytoplasm [GO:0005737] actin binding [GO:0003779] GO:0003779; GO:0005737; GO:0007520; GO:1901739 reviewed Drosophila melanogaster (Fruit fly) 19 TRINITY_DN274840_c0_g1 18.05708077 13.08541244 77.70118076 2.47E-10 1.09E-08 Q724J4 TRINITY_DN274840_c0_g1_i1 2.10E-10 Bifunctional protein TilS/HprT [Includes: tRNA(Ile)-lysidine synthase (EC 6.3.4.19) (tRNA(Ile)-2-lysyl-cytidine synthase) (tRNA(Ile)-lysidine synthetase); Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (HGPRTase) (EC 2.4.2.8)] purine ribonucleoside salvage [GO:0006166]; tRNA modification [GO:0006400] cytoplasm [GO:0005737] "ATP binding [GO:0005524]; guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]; metal ion binding [GO:0046872]" GO:0004422; GO:0005524; GO:0005737; GO:0006166; GO:0006400; GO:0016879; GO:0046872; GO:0052657 reviewed Listeria monocytogenes serotype 4b (strain F2365) 20 TRINITY_DN276416_c0_g1 19.5664093 10.89077279 80.93201806 8.60E-10 3.15E-08 Q8CHB8 TRINITY_DN276416_c0_g1_i1 1.40E-12 Tubulin polyglutamylase TTLL5 (EC 6.-.-.-) (Tubulin--tyrosine ligase-like protein 5) fertilization [GO:0009566]; flagellated sperm motility [GO:0030317]; protein polyglutamylation [GO:0018095]; retina development in camera-type eye [GO:0060041]; spermatogenesis [GO:0007283]; sperm axoneme assembly [GO:0007288] centrosome [GO:0005813]; cilium [GO:0005929]; cytosol [GO:0005829]; microtubule [GO:0005874]; nucleus [GO:0005634]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; ligase activity [GO:0016874] GO:0005524; GO:0005634; GO:0005813; GO:0005829; GO:0005874; GO:0005886; GO:0005929; GO:0007283; GO:0007288; GO:0009566; GO:0016874; GO:0018095; GO:0030317; GO:0060041 reviewed Mus musculus (Mouse) 21 TRINITY_DN277082_c0_g1 20.31931657 14.32280678 105.9650327 5.02E-12 6.43E-10 Q8C0T9 TRINITY_DN277082_c0_g1_i1 5.70E-13 Adenylate cyclase type 10 (EC 4.6.1.1) (Germ cell soluble adenylyl cyclase) (sAC) (Testicular soluble adenylyl cyclase) cAMP biosynthetic process [GO:0006171]; cellular response to inorganic substance [GO:0071241]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; intracellular signal transduction [GO:0035556]; positive regulation of apoptotic process [GO:0043065]; spermatogenesis [GO:0007283] apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; axon [GO:0030424]; basal part of cell [GO:0045178]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular region [GO:0005576]; growth cone [GO:0030426]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; motile cilium [GO:0031514]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] adenylate cyclase activity [GO:0004016]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; bicarbonate binding [GO:0071890]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145] GO:0000287; GO:0003351; GO:0004016; GO:0005524; GO:0005576; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0006171; GO:0007283; GO:0015630; GO:0016020; GO:0016324; GO:0030145; GO:0030424; GO:0030425; GO:0030426; GO:0031514; GO:0035556; GO:0043025; GO:0043065; GO:0045177; GO:0045178; GO:0048471; GO:0051117; GO:0071241; GO:0071890 reviewed Mus musculus (Mouse) 22 TRINITY_DN277202_c0_g1 15.84070488 9.144768434 36.39285442 1.61E-06 4.48E-05 Q5R3I4 TRINITY_DN277202_c0_g1_i1 4.80E-06 Tetratricopeptide repeat protein 38 (TPR repeat protein 38) extracellular exosome [GO:0070062] GO:0070062 reviewed Homo sapiens (Human) 23 TRINITY_DN277209_c0_g1 8.619151792 7.606074106 9.847680124 0.003692889 0.047305904 E5A7I6 TRINITY_DN277209_c0_g1_i1 1.70E-12 Carboxypeptidase Y homolog A (EC 3.4.16.5) vacuole [GO:0005773] serine-type carboxypeptidase activity [GO:0004185] GO:0004185; GO:0005773 reviewed Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8) (Blackleg fungus) (Phoma lingam) 24 TRINITY_DN277328_c0_g1 20.32510447 12.02493955 108.6143054 1.06E-11 8.02E-10 Q55E58 TRINITY_DN277328_c0_g1_i1 8.00E-07 Probable serine/threonine-protein kinase pats1 (EC 2.7.11.1) (Protein associated with the transduction of signal 1) cheating during chimeric sorocarp development [GO:0099139]; mitotic cytokinesis [GO:0000281]; protein dephosphorylation [GO:0006470] actomyosin [GO:0042641] ATP binding [GO:0005524]; GTP binding [GO:0005525]; phosphoprotein phosphatase activity [GO:0004721]; protein serine/threonine kinase activity [GO:0004674] GO:0000281; GO:0004674; GO:0004721; GO:0005524; GO:0005525; GO:0006470; GO:0042641; GO:0099139 reviewed Dictyostelium discoideum (Slime mold) 25 TRINITY_DN277371_c0_g1 18.46826037 14.39292493 88.41224435 5.08E-11 2.83E-09 O31782 TRINITY_DN277371_c0_g1_i3 3.40E-16 Polyketide synthase PksN (EC 2.3.1.-) metabolic process [GO:0008152] cytoplasm [GO:0005737] "ligase activity [GO:0016874]; phosphopantetheine binding [GO:0031177]; transferase activity, transferring acyl groups [GO:0016746]" GO:0005737; GO:0008152; GO:0016746; GO:0016874; GO:0031177 reviewed Bacillus subtilis (strain 168) 26 TRINITY_DN278382_c0_g1 19.48864017 10.85987755 79.18325597 1.08E-09 3.86E-08 Q9C1X4 TRINITY_DN278382_c0_g1_i1 5.80E-06 Uncharacterized RING finger protein P32A8.03c proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein modification by small protein conjugation or removal [GO:0070647]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511] nucleus [GO:0005634] ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] GO:0005634; GO:0006511; GO:0008270; GO:0030433; GO:0043161; GO:0061630; GO:0070647 reviewed Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) 27 TRINITY_DN278906_c0_g1 18.53849221 11.81185265 97.69312895 3.84E-11 2.38E-09 Q1DDU5 TRINITY_DN278906_c0_g1_i1 1.50E-105 Kynureninase (EC 3.7.1.3) (L-kynurenine hydrolase) 'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; anthranilate metabolic process [GO:0043420]; L-kynurenine catabolic process [GO:0097053]; quinolinate biosynthetic process [GO:0019805]; tryptophan catabolic process [GO:0006569] cytoplasm [GO:0005737] kynureninase activity [GO:0030429]; pyridoxal phosphate binding [GO:0030170] GO:0005737; GO:0006569; GO:0019805; GO:0030170; GO:0030429; GO:0034354; GO:0043420; GO:0097053 reviewed Myxococcus xanthus (strain DK 1622) 28 TRINITY_DN278965_c0_g1 10.93131288 7.318892386 11.78080911 0.001861728 0.026498592 Q20065 TRINITY_DN278965_c0_g1_i6 1.10E-09 "Prolyl 4-hydroxylase subunit alpha-2 (4-PH alpha-2) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-2)" macromolecule modification [GO:0043412]; oxidation-reduction process [GO:0055114]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788] "iron ion binding [GO:0005506]; L-ascorbic acid binding [GO:0031418]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peptidyl-proline 4-dioxygenase activity [GO:0031545]; procollagen-proline 4-dioxygenase activity [GO:0004656]" GO:0004656; GO:0005506; GO:0005783; GO:0005788; GO:0016702; GO:0018401; GO:0031418; GO:0031545; GO:0043412; GO:0055114 reviewed Caenorhabditis elegans 29 TRINITY_DN278968_c0_g1 17.0883166 10.38151164 57.07982292 1.53E-08 4.90E-07 O14792 TRINITY_DN278968_c0_g1_i1 8.90E-10 Heparan sulfate glucosamine 3-O-sulfotransferase 1 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1) (3-OST-1) (Heparan sulfate 3-O-sulfotransferase 1) (h3-OST-1) glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012] Golgi lumen [GO:0005796] [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity [GO:0008467]; heparan sulfate sulfotransferase activity [GO:0034483]; sulfotransferase activity [GO:0008146] GO:0005796; GO:0006024; GO:0008146; GO:0008467; GO:0015012; GO:0034483 reviewed Homo sapiens (Human) 30 TRINITY_DN292324_c0_g1 18.13456973 14.03206022 89.96764211 4.08E-11 2.38E-09 Q8N8W4 TRINITY_DN292324_c0_g1_i1 1.50E-09 Patatin-like phospholipase domain-containing protein 1 (EC 3.1.1.-) lipid homeostasis [GO:0055088]; triglyceride catabolic process [GO:0019433] cytoplasm [GO:0005737]; lipid droplet [GO:0005811]; membrane [GO:0016020] triglyceride lipase activity [GO:0004806] GO:0004806; GO:0005737; GO:0005811; GO:0016020; GO:0019433; GO:0055088 reviewed Homo sapiens (Human) 31 TRINITY_DN292353_c0_g1 17.61338288 12.25644817 92.77750616 2.77E-11 1.87E-09 P08842 TRINITY_DN292353_c0_g1_i1 1.10E-84 Steryl-sulfatase (EC 3.1.6.2) (Arylsulfatase C) (ASC) (Estrone sulfatase) (Steroid sulfatase) (Steryl-sulfate sulfohydrolase) epidermis development [GO:0008544]; female pregnancy [GO:0007565]; glycosphingolipid metabolic process [GO:0006687]; steroid catabolic process [GO:0006706] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; membrane [GO:0016020]; plasma membrane [GO:0005886] arylsulfatase activity [GO:0004065]; metal ion binding [GO:0046872]; steryl-sulfatase activity [GO:0004773]; sulfuric ester hydrolase activity [GO:0008484] GO:0004065; GO:0004773; GO:0005764; GO:0005768; GO:0005783; GO:0005788; GO:0005789; GO:0005794; GO:0005886; GO:0006687; GO:0006706; GO:0007565; GO:0008484; GO:0008544; GO:0016020; GO:0016021; GO:0043231; GO:0046872 reviewed Homo sapiens (Human) 32 TRINITY_DN292370_c1_g7 -4.908719102 13.12845064 13.54324739 0.000794882 0.013576583 P20825 TRINITY_DN292370_c1_g7_i1 4.20E-16 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] DNA integration [GO:0015074] aspartic-type endopeptidase activity [GO:0004190]; endonuclease activity [GO:0004519]; nucleic acid binding [GO:0003676]; RNA-directed DNA polymerase activity [GO:0003964] GO:0003676; GO:0003964; GO:0004190; GO:0004519; GO:0015074 reviewed Drosophila melanogaster (Fruit fly) 33 TRINITY_DN293386_c0_g1 13.39447355 8.177659176 18.62221474 0.000176352 0.003643658 P10567 TRINITY_DN293386_c0_g1_i1 1.50E-53 Paramyosin (Uncoordinated protein 15) locomotion [GO:0040011]; positive regulation of ovulation [GO:0060279]; positive regulation of sarcomere organization [GO:0060298]; regulation of cytoskeleton organization [GO:0051493]; skeletal muscle myosin thick filament assembly [GO:0030241] A band [GO:0031672]; microtubule organizing center [GO:0005815]; myosin filament [GO:0032982] cytoskeletal protein binding [GO:0008092]; motor activity [GO:0003774]; protein kinase binding [GO:0019901]; SH3 domain binding [GO:0017124] GO:0003774; GO:0005815; GO:0008092; GO:0017124; GO:0019901; GO:0030241; GO:0031672; GO:0032982; GO:0040011; GO:0051493; GO:0060279; GO:0060298 reviewed Caenorhabditis elegans 34 TRINITY_DN293894_c0_g2 18.76496946 13.89717117 111.8221043 2.47E-12 6.02E-10 Q8TZW4 TRINITY_DN293894_c0_g2_i1 3.50E-19 Lysyl aminopeptidase (EC 3.4.11.15) aminopeptidase activity [GO:0004177]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237] GO:0004177; GO:0008237; GO:0046872 reviewed Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) 35 TRINITY_DN294657_c0_g1 18.04139991 11.37621452 81.06156336 3.40E-10 1.36E-08 O35587 TRINITY_DN294657_c0_g1_i1 1.80E-09 Transmembrane protein Tmp21 (21 kDa transmembrane-trafficking protein) (Integral membrane protein p23) (p24 family protein delta-1) (p24delta1) "COPI-coated vesicle budding [GO:0035964]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886]; regulated exocytosis [GO:0045055]; regulation of amyloid-beta formation [GO:1902003]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]" COPI-coated vesicle [GO:0030137]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; endoplasmic reticulum membrane [GO:0005789]; gamma-secretase complex [GO:0070765]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; melanosome [GO:0042470]; plasma membrane [GO:0005886]; trans-Golgi network transport vesicle [GO:0030140]; transport vesicle membrane [GO:0030658]; zymogen granule membrane [GO:0042589] syntaxin binding [GO:0019905] GO:0000139; GO:0005789; GO:0005886; GO:0006886; GO:0006890; GO:0007030; GO:0016021; GO:0019905; GO:0030137; GO:0030140; GO:0030658; GO:0033116; GO:0035964; GO:0042470; GO:0042589; GO:0045055; GO:0070765; GO:1902003 reviewed Mesocricetus auratus (Golden hamster) 36 TRINITY_DN294754_c0_g1 16.62959835 14.79364867 70.34824975 8.04E-10 3.03E-08 Q8R151 TRINITY_DN294754_c0_g1_i2 5.40E-07 NFX1-type zinc finger-containing protein 1 chromatin silencing at centromere [GO:0030702]; chromatin silencing by small RNA [GO:0031048] "chromosome, centromeric region [GO:0000775]; nuclear RNA-directed RNA polymerase complex [GO:0031380]; nucleus [GO:0005634]" DNA-binding transcription factor activity [GO:0003700]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270] GO:0000775; GO:0003700; GO:0003723; GO:0005634; GO:0008270; GO:0030702; GO:0031048; GO:0031380 reviewed Mus musculus (Mouse) 37 TRINITY_DN294773_c0_g2 19.48342366 14.07990938 112.5191415 2.28E-12 6.02E-10 Q8NBK3 TRINITY_DN294773_c0_g2_i1 9.90E-68 Formylglycine-generating enzyme (FGE) (EC 1.8.3.7) (C-alpha-formylglycine-generating enzyme 1) (Sulfatase-modifying factor 1) glycosphingolipid metabolic process [GO:0006687]; post-translational protein modification [GO:0043687]; protein oxidation [GO:0018158] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788] cupric ion binding [GO:1903135]; Formylglycine-generating oxidase activity [GO:0120147]; oxidoreductase activity [GO:0016491]; protein homodimerization activity [GO:0042803] GO:0005783; GO:0005788; GO:0006687; GO:0016491; GO:0018158; GO:0042803; GO:0043687; GO:0120147; GO:1903135 reviewed Homo sapiens (Human) 38 TRINITY_DN294773_c0_g3 19.96223054 11.05981635 85.29101587 4.92E-10 1.91E-08 Q8NBK3 TRINITY_DN294773_c0_g3_i1 1.70E-67 Formylglycine-generating enzyme (FGE) (EC 1.8.3.7) (C-alpha-formylglycine-generating enzyme 1) (Sulfatase-modifying factor 1) glycosphingolipid metabolic process [GO:0006687]; post-translational protein modification [GO:0043687]; protein oxidation [GO:0018158] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788] cupric ion binding [GO:1903135]; Formylglycine-generating oxidase activity [GO:0120147]; oxidoreductase activity [GO:0016491]; protein homodimerization activity [GO:0042803] GO:0005783; GO:0005788; GO:0006687; GO:0016491; GO:0018158; GO:0042803; GO:0043687; GO:0120147; GO:1903135 reviewed Homo sapiens (Human) 39 TRINITY_DN294779_c0_g2 -7.295119629 15.01902166 27.1251209 9.02E-06 0.000206343 P35133 TRINITY_DN294779_c0_g2_i1 7.10E-06 Ubiquitin-conjugating enzyme E2 10 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 10) (Ubiquitin carrier protein 10/12) (Ubiquitin-conjugating enzyme E2-17 kDa 10/12) (Ubiquitin-protein ligase 10/12) ubiquitin-dependent protein catabolic process [GO:0006511] ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842] GO:0004842; GO:0005524; GO:0006511; GO:0031625; GO:0061631 reviewed Arabidopsis thaliana (Mouse-ear cress) 40 TRINITY_DN294779_c1_g3 -4.686734484 14.71783809 13.09074107 0.000945333 0.015726909 Q9ZT94 TRINITY_DN294779_c1_g3_i1 2.10E-28 Retrovirus-related Pol polyprotein from transposon RE2 (Retro element 2) (AtRE2) [Includes: Protease RE2 (EC 3.4.23.-); Reverse transcriptase RE2 (EC 2.7.7.49); Endonuclease RE2] DNA integration [GO:0015074]; DNA recombination [GO:0006310] retrotransposon nucleocapsid [GO:0000943] aspartic-type endopeptidase activity [GO:0004190]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; RNA-directed DNA polymerase activity [GO:0003964] GO:0000943; GO:0003676; GO:0003964; GO:0004190; GO:0004519; GO:0006310; GO:0015074; GO:0046872 reviewed Arabidopsis thaliana (Mouse-ear cress) 41 TRINITY_DN295087_c0_g1 10.70477614 7.260304574 11.08269536 0.002430577 0.033479234 P27484 TRINITY_DN295087_c0_g1_i3 7.00E-07 Glycine-rich protein 2 RNA binding [GO:0003723]; zinc ion binding [GO:0008270] GO:0003723; GO:0008270 reviewed Nicotiana sylvestris (Wood tobacco) (South American tobacco) 42 TRINITY_DN295214_c0_g1 9.509699656 10.30032912 12.86022244 0.001033399 0.016547294 P29830 TRINITY_DN295214_c0_g1_i4 1.30E-08 17.6 kDa class II heat shock protein (17.6 kDa heat shock protein) (AtHsp17.6) protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; response to heat [GO:0009408]; response to high light intensity [GO:0009644]; response to hydrogen peroxide [GO:0042542]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651] cytoplasm [GO:0005737] protein self-association [GO:0043621]; unfolded protein binding [GO:0051082] GO:0000302; GO:0005737; GO:0006457; GO:0009408; GO:0009644; GO:0009651; GO:0042542; GO:0043621; GO:0051082; GO:0051259 reviewed Arabidopsis thaliana (Mouse-ear cress) 43 TRINITY_DN295214_c0_g2 9.504195497 7.581097991 11.85305423 0.001656576 0.024391652 P29830 TRINITY_DN295214_c0_g2_i3 1.70E-08 17.6 kDa class II heat shock protein (17.6 kDa heat shock protein) (AtHsp17.6) protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; response to heat [GO:0009408]; response to high light intensity [GO:0009644]; response to hydrogen peroxide [GO:0042542]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651] cytoplasm [GO:0005737] protein self-association [GO:0043621]; unfolded protein binding [GO:0051082] GO:0000302; GO:0005737; GO:0006457; GO:0009408; GO:0009644; GO:0009651; GO:0042542; GO:0043621; GO:0051082; GO:0051259 reviewed Arabidopsis thaliana (Mouse-ear cress) 44 TRINITY_DN295219_c1_g1 21.01153249 12.2939367 117.876732 3.87E-12 6.02E-10 O26884 TRINITY_DN295219_c1_g1_i2 8.80E-43 Uncharacterized protein MTH_793 "transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]" GO:0016747 reviewed Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum) 45 TRINITY_DN295224_c1_g1 17.63046013 12.03698844 89.99414632 4.07E-11 2.38E-09 Q1ZXD6 TRINITY_DN295224_c1_g1_i1 8.00E-15 Probable serine/threonine-protein kinase roco5 (EC 2.7.11.1) (Ras of complex proteins and C-terminal of roc 5) regulation of Rho protein signal transduction [GO:0035023]; sorocarp development [GO:0030587] ATP binding [GO:0005524]; GTP binding [GO:0005525]; protein serine/threonine kinase activity [GO:0004674]; Rho guanyl-nucleotide exchange factor activity [GO:0005089] GO:0004674; GO:0005089; GO:0005524; GO:0005525; GO:0030587; GO:0035023 reviewed Dictyostelium discoideum (Slime mold) 46 TRINITY_DN295269_c0_g2 13.3983429 8.204183052 29.20205631 8.92E-06 0.000206343 Q5JJY4 TRINITY_DN295269_c0_g2_i1 2.40E-08 Protein kinase and PP2C-like domain-containing protein [Includes: Probable serine/threonine-protein kinase Os01g0541900 (EC 2.7.11.1); Probable protein phosphatase 2C 4 (OsPP2C04) (EC 3.1.3.16)] ATP binding [GO:0005524]; magnesium-dependent protein serine/threonine phosphatase activity [GO:0004724]; metal ion binding [GO:0046872]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine phosphatase activity [GO:0004722] GO:0004674; GO:0004722; GO:0004724; GO:0005524; GO:0046872 reviewed Oryza sativa subsp. japonica (Rice) 47 TRINITY_DN296218_c0_g2 -5.287651501 10.7817801 11.62893705 0.001678225 0.024429616 Q9ZT94 TRINITY_DN296218_c0_g2_i5 2.30E-10 Retrovirus-related Pol polyprotein from transposon RE2 (Retro element 2) (AtRE2) [Includes: Protease RE2 (EC 3.4.23.-); Reverse transcriptase RE2 (EC 2.7.7.49); Endonuclease RE2] DNA integration [GO:0015074]; DNA recombination [GO:0006310] retrotransposon nucleocapsid [GO:0000943] aspartic-type endopeptidase activity [GO:0004190]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; RNA-directed DNA polymerase activity [GO:0003964] GO:0000943; GO:0003676; GO:0003964; GO:0004190; GO:0004519; GO:0006310; GO:0015074; GO:0046872 reviewed Arabidopsis thaliana (Mouse-ear cress) 48 TRINITY_DN296373_c0_g2 12.20310245 7.746708158 20.62725105 9.50E-05 0.001995984 O88379 TRINITY_DN296373_c0_g2_i1 5.10E-06 Bromodomain adjacent to zinc finger domain protein 1A (Cbp146) chromatin remodeling [GO:0006338]; DNA-dependent DNA replication [GO:0006261] CHRAC [GO:0008623]; nuclear chromosome [GO:0000228] metal ion binding [GO:0046872] GO:0000228; GO:0006261; GO:0006338; GO:0008623; GO:0046872 reviewed Mus musculus (Mouse) 49 TRINITY_DN296708_c0_g1 21.68291002 14.66491937 140.7743929 1.09E-13 1.40E-10 Q54CI5 TRINITY_DN296708_c0_g1_i1 2.10E-13 DPH4 homolog (DnaJ homolog subfamily C member 24) peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]; tRNA wobble uridine modification [GO:0002098] cytosol [GO:0005829]; nucleus [GO:0005634] metal ion binding [GO:0046872] GO:0002098; GO:0005634; GO:0005829; GO:0017183; GO:0046872 reviewed Dictyostelium discoideum (Slime mold) 50 TRINITY_DN296759_c4_g1 10.18549877 8.505905311 15.93328005 0.000328193 0.006005931 P02556 TRINITY_DN296759_c4_g1_i1 7.60E-08 Tubulin beta chain (Beta-tubulin) (Fragment) microtubule-based process [GO:0007017] cytoplasm [GO:0005737]; microtubule [GO:0005874] GTP binding [GO:0005525]; structural constituent of cytoskeleton [GO:0005200] GO:0005200; GO:0005525; GO:0005737; GO:0005874; GO:0007017 reviewed Lytechinus pictus (Painted sea urchin) 51 TRINITY_DN298167_c1_g1 -6.416088008 14.40118937 20.59162575 6.67E-05 0.001423701 Q94HW2 TRINITY_DN298167_c1_g1_i6 8.50E-06 Retrovirus-related Pol polyprotein from transposon RE1 (Retro element 1) (AtRE1) [Includes: Protease RE1 (EC 3.4.23.-); Reverse transcriptase RE1 (EC 2.7.7.49); Endonuclease RE1] DNA integration [GO:0015074]; DNA recombination [GO:0006310] retrotransposon nucleocapsid [GO:0000943] aspartic-type endopeptidase activity [GO:0004190]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; RNA-directed DNA polymerase activity [GO:0003964] GO:0000943; GO:0003676; GO:0003964; GO:0004190; GO:0004519; GO:0006310; GO:0015074; GO:0046872 reviewed Arabidopsis thaliana (Mouse-ear cress) 52 TRINITY_DN298834_c0_g6 11.02570006 7.581639882 17.02635536 0.000294612 0.005469542 P78970 TRINITY_DN298834_c0_g6_i1 2.50E-13 Sphingosine N-acyltransferase lag1 (EC 2.3.1.24) (Longevity assurance factor 1) (Longevity assurance protein 1) ceramide biosynthetic process [GO:0046513]; vacuolar acidification [GO:0007035] endoplasmic reticulum [GO:0005783]; integral component of endoplasmic reticulum membrane [GO:0030176] sphingosine N-acyltransferase activity [GO:0050291] GO:0005783; GO:0007035; GO:0030176; GO:0046513; GO:0050291 reviewed Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) 53 TRINITY_DN299755_c1_g3 15.21328196 8.894815231 34.98811912 2.21E-06 5.91E-05 P34221 TRINITY_DN299755_c1_g3_i4 1.30E-17 Protein phosphatase 2C homolog 3 (PP2C-3) (EC 3.1.3.16) cellular response to osmotic stress [GO:0071470]; inactivation of MAPK activity [GO:0000188]; negative regulation of stress-activated MAPK cascade [GO:0032873]; protein dephosphorylation [GO:0006470]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079] cytoplasm [GO:0005737]; nucleus [GO:0005634] magnesium-dependent protein serine/threonine phosphatase activity [GO:0004724]; MAP kinase serine/threonine phosphatase activity [GO:1990439]; metal ion binding [GO:0046872]; protein serine/threonine phosphatase activity [GO:0004722] GO:0000079; GO:0000188; GO:0004722; GO:0004724; GO:0005634; GO:0005737; GO:0006470; GO:0032873; GO:0046872; GO:0071470; GO:1990439 reviewed Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 54 TRINITY_DN299789_c0_g2 18.66962268 12.73087676 82.36110774 2.84E-10 1.21E-08 Q55E58 TRINITY_DN299789_c0_g2_i1 4.60E-20 Probable serine/threonine-protein kinase pats1 (EC 2.7.11.1) (Protein associated with the transduction of signal 1) cheating during chimeric sorocarp development [GO:0099139]; mitotic cytokinesis [GO:0000281]; protein dephosphorylation [GO:0006470] actomyosin [GO:0042641] ATP binding [GO:0005524]; GTP binding [GO:0005525]; phosphoprotein phosphatase activity [GO:0004721]; protein serine/threonine kinase activity [GO:0004674] GO:0000281; GO:0004674; GO:0004721; GO:0005524; GO:0005525; GO:0006470; GO:0042641; GO:0099139 reviewed Dictyostelium discoideum (Slime mold) 55 TRINITY_DN310761_c3_g1 -8.54953016 13.15583028 28.65438157 5.84E-06 0.000141095 P93285 TRINITY_DN310761_c3_g1_i4 1.90E-07 Cytochrome c oxidase subunit 2 (EC 1.9.3.1) (Cytochrome c oxidase polypeptide II) integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respirasome [GO:0070469] copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129] GO:0004129; GO:0005507; GO:0005743; GO:0016021; GO:0070469 reviewed Arabidopsis thaliana (Mouse-ear cress) 56 TRINITY_DN310761_c3_g3 -7.856979701 15.13332378 29.28617321 4.89E-06 0.000120539 P93285 TRINITY_DN310761_c3_g3_i3 3.00E-10 Cytochrome c oxidase subunit 2 (EC 1.9.3.1) (Cytochrome c oxidase polypeptide II) integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respirasome [GO:0070469] copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129] GO:0004129; GO:0005507; GO:0005743; GO:0016021; GO:0070469 reviewed Arabidopsis thaliana (Mouse-ear cress) 57 TRINITY_DN310763_c1_g1 9.375239699 6.93898092 10.55254341 0.002987654 0.039455514 Q94HW2 TRINITY_DN310763_c1_g1_i1 1.10E-11 Retrovirus-related Pol polyprotein from transposon RE1 (Retro element 1) (AtRE1) [Includes: Protease RE1 (EC 3.4.23.-); Reverse transcriptase RE1 (EC 2.7.7.49); Endonuclease RE1] DNA integration [GO:0015074]; DNA recombination [GO:0006310] retrotransposon nucleocapsid [GO:0000943] aspartic-type endopeptidase activity [GO:0004190]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; RNA-directed DNA polymerase activity [GO:0003964] GO:0000943; GO:0003676; GO:0003964; GO:0004190; GO:0004519; GO:0006310; GO:0015074; GO:0046872 reviewed Arabidopsis thaliana (Mouse-ear cress) 58 TRINITY_DN310763_c3_g1 -10.51187197 7.853460209 17.00375381 0.00024408 0.004737366 Q9ZT94 TRINITY_DN310763_c3_g1_i1 3.40E-08 Retrovirus-related Pol polyprotein from transposon RE2 (Retro element 2) (AtRE2) [Includes: Protease RE2 (EC 3.4.23.-); Reverse transcriptase RE2 (EC 2.7.7.49); Endonuclease RE2] DNA integration [GO:0015074]; DNA recombination [GO:0006310] retrotransposon nucleocapsid [GO:0000943] aspartic-type endopeptidase activity [GO:0004190]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; RNA-directed DNA polymerase activity [GO:0003964] GO:0000943; GO:0003676; GO:0003964; GO:0004190; GO:0004519; GO:0006310; GO:0015074; GO:0046872 reviewed Arabidopsis thaliana (Mouse-ear cress) 59 TRINITY_DN311418_c0_g1 22.38336023 12.25049505 124.1045562 7.41E-12 7.09E-10 C3K732 TRINITY_DN311418_c0_g1_i1 6.20E-24 Thiopurine S-methyltransferase (EC 2.1.1.67) (Thiopurine methyltransferase) response to metal ion [GO:0010038] cytoplasm [GO:0005737] thiopurine S-methyltransferase activity [GO:0008119] GO:0005737; GO:0008119; GO:0010038 reviewed Pseudomonas fluorescens (strain SBW25) 60 TRINITY_DN311461_c0_g1 19.65830343 13.96098349 99.11265671 1.19E-11 8.49E-10 O34787 TRINITY_DN311461_c0_g1_i1 5.80E-80 Polyketide biosynthesis protein PksE [Includes: Malonyl CoA-acyl carrier protein transacylase (MCT) (EC 2.3.1.39)] antibiotic biosynthetic process [GO:0017000]; fatty acid biosynthetic process [GO:0006633] cytosol [GO:0005829] [acyl-carrier-protein] S-malonyltransferase activity [GO:0004314]; nitronate monooxygenase activity [GO:0018580] GO:0004314; GO:0005829; GO:0006633; GO:0017000; GO:0018580 reviewed Bacillus subtilis (strain 168) 61 TRINITY_DN311484_c1_g5 14.16580307 8.473310482 33.13832524 3.40E-06 8.55E-05 Q52828 TRINITY_DN311484_c1_g5_i1 2.30E-18 Protein GstA transferase activity [GO:0016740] GO:0016740 reviewed Rhizobium leguminosarum 62 TRINITY_DN311486_c4_g1 -7.339634451 11.51295582 21.89026863 4.39E-05 0.000953623 Q94HW2 TRINITY_DN311486_c4_g1_i7 4.20E-10 Retrovirus-related Pol polyprotein from transposon RE1 (Retro element 1) (AtRE1) [Includes: Protease RE1 (EC 3.4.23.-); Reverse transcriptase RE1 (EC 2.7.7.49); Endonuclease RE1] DNA integration [GO:0015074]; DNA recombination [GO:0006310] retrotransposon nucleocapsid [GO:0000943] aspartic-type endopeptidase activity [GO:0004190]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; RNA-directed DNA polymerase activity [GO:0003964] GO:0000943; GO:0003676; GO:0003964; GO:0004190; GO:0004519; GO:0006310; GO:0015074; GO:0046872 reviewed Arabidopsis thaliana (Mouse-ear cress) 63 TRINITY_DN311489_c3_g5 13.50661112 8.196502905 29.76671118 7.74E-06 0.000183509 Q9H0A6 TRINITY_DN311489_c3_g5_i3 4.50E-15 RING finger protein 32 aggresome [GO:0016235]; endosome [GO:0005768] metal ion binding [GO:0046872] GO:0005768; GO:0016235; GO:0046872 reviewed Homo sapiens (Human) 64 TRINITY_DN311493_c0_g1 11.38031087 9.699307412 14.23156426 0.000612911 0.010755327 P13607 TRINITY_DN311493_c0_g1_i1 6.20E-31 Sodium/potassium-transporting ATPase subunit alpha (Na(+)/K(+) ATPase alpha subunit) (EC 7.2.2.13) (Sodium pump subunit alpha) "adult locomotory behavior [GO:0008344]; ATP hydrolysis coupled proton transport [GO:0015991]; cation transport [GO:0006812]; cellular potassium ion homeostasis [GO:0030007]; cellular sodium ion homeostasis [GO:0006883]; chemical synaptic transmission [GO:0007268]; determination of adult lifespan [GO:0008340]; jump response [GO:0007630]; locomotory behavior [GO:0007626]; neuromuscular process [GO:0050905]; potassium ion import across plasma membrane [GO:1990573]; regulation of tube diameter, open tracheal system [GO:0035158]; regulation of tube length, open tracheal system [GO:0035159]; response to mechanical stimulus [GO:0009612]; response to temperature stimulus [GO:0009266]; sensory perception of sound [GO:0007605]; septate junction assembly [GO:0019991]; sodium ion export across plasma membrane [GO:0036376]; synaptic growth at neuromuscular junction [GO:0051124]; tissue homeostasis [GO:0001894]; trachea morphogenesis [GO:0060439]" basolateral plasma membrane [GO:0016323]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; septate junction [GO:0005918]; sodium:potassium-exchanging ATPase complex [GO:0005890] ATP binding [GO:0005524]; sodium:potassium-exchanging ATPase activity [GO:0005391] GO:0001894; GO:0005391; GO:0005524; GO:0005634; GO:0005737; GO:0005886; GO:0005890; GO:0005918; GO:0006812; GO:0006883; GO:0007268; GO:0007605; GO:0007626; GO:0007630; GO:0008340; GO:0008344; GO:0009266; GO:0009612; GO:0015991; GO:0016323; GO:0019991; GO:0030007; GO:0035158; GO:0035159; GO:0036376; GO:0050905; GO:0051124; GO:0060439; GO:1990573 reviewed Drosophila melanogaster (Fruit fly) 65 TRINITY_DN311716_c0_g1 18.04054754 11.37183288 87.84648429 1.35E-10 6.16E-09 Q8K4H1 TRINITY_DN311716_c0_g1_i1 1.40E-07 Kynurenine formamidase (KFA) (KFase) (EC 3.5.1.9) (Arylformamidase) (N-formylkynurenine formamidase) (FKF) 'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; tryptophan catabolic process to kynurenine [GO:0019441] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634] arylformamidase activity [GO:0004061] GO:0004061; GO:0005634; GO:0005737; GO:0005829; GO:0019441; GO:0034354 reviewed Mus musculus (Mouse) 66 TRINITY_DN311716_c0_g2 20.77659826 11.47194003 102.5660702 6.51E-11 3.47E-09 Q8N3Y7 TRINITY_DN311716_c0_g2_i1 6.70E-24 Epidermal retinol dehydrogenase 2 (EPHD-2) (RDH-E2) (EC 1.1.1.105) (Retinal short-chain dehydrogenase reductase 2) (retSDR2) (Short-chain dehydrogenase/reductase family 16C member 5) keratinocyte proliferation [GO:0043616]; negative regulation of histone acetylation [GO:0035067]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of histone deacetylation [GO:0031065]; retinal metabolic process [GO:0042574]; retinol metabolic process [GO:0042572] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; lipid droplet [GO:0005811]; nucleus [GO:0005634]; transcriptional repressor complex [GO:0017053] activating transcription factor binding [GO:0033613]; retinol dehydrogenase activity [GO:0004745]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134] GO:0000122; GO:0003714; GO:0004745; GO:0005634; GO:0005783; GO:0005789; GO:0005811; GO:0008134; GO:0016021; GO:0017053; GO:0031065; GO:0033613; GO:0035067; GO:0042572; GO:0042574; GO:0043616 reviewed Homo sapiens (Human) 67 TRINITY_DN311731_c0_g1 13.0577743 8.022670624 26.95866432 1.59E-05 0.00035827 G5EEM5 TRINITY_DN311731_c0_g1_i1 6.60E-07 Zygote defective protein 9 cell division [GO:0051301]; centrosome duplication [GO:0051298]; embryo development ending in birth or egg hatching [GO:0009792]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; meiotic spindle organization [GO:0000212]; microtubule-based process [GO:0007017]; microtubule polymerization [GO:0046785]; spindle elongation [GO:0051231]; spindle organization [GO:0007051] centrosome [GO:0005813]; cytoplasm [GO:0005737]; kinetochore [GO:0000776]; meiotic spindle [GO:0072687]; microtubule [GO:0005874]; spindle pole [GO:0000922] microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010] GO:0000212; GO:0000776; GO:0000922; GO:0005737; GO:0005813; GO:0005874; GO:0007017; GO:0007051; GO:0008017; GO:0009792; GO:0030951; GO:0046785; GO:0051010; GO:0051231; GO:0051298; GO:0051301; GO:0072687 reviewed Caenorhabditis elegans 68 TRINITY_DN311753_c2_g6 15.358577 9.301833048 34.63662028 2.40E-06 6.27E-05 P04146 TRINITY_DN311753_c2_g6_i1 1.50E-06 Copia protein (Gag-int-pol protein) [Cleaved into: Copia VLP protein; Copia protease (EC 3.4.23.-)] DNA integration [GO:0015074] retrotransposon nucleocapsid [GO:0000943] aspartic-type endopeptidase activity [GO:0004190]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]; zinc ion binding [GO:0008270] GO:0000943; GO:0003676; GO:0004190; GO:0005524; GO:0008270; GO:0015074 reviewed Drosophila melanogaster (Fruit fly) 69 TRINITY_DN312002_c0_g1 18.65497786 13.95319864 102.1568598 8.08E-12 7.09E-10 A8X0C4 TRINITY_DN312002_c0_g1_i7 7.10E-11 Serine/threonine-protein kinase par-4 (EC 2.7.11.1) establishment of cell polarity [GO:0030010]; glucose homeostasis [GO:0042593]; mitotic cell cycle [GO:0000278]; multicellular organism development [GO:0007275]; regulation of cell growth [GO:0001558]; regulation of cytokinesis [GO:0032465] cell cortex [GO:0005938]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; spindle pole [GO:0000922] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein kinase activator activity [GO:0030295]; protein serine/threonine kinase activity [GO:0004674] GO:0000278; GO:0000922; GO:0001558; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005938; GO:0007275; GO:0030010; GO:0030295; GO:0032465; GO:0042593; GO:0046872 reviewed Caenorhabditis briggsae 70 TRINITY_DN312005_c1_g1 9.770060165 7.021388309 13.98677469 0.000830329 0.013995414 Q4PBY6 TRINITY_DN312005_c1_g1_i1 6.30E-06 "Cytochrome c peroxidase, mitochondrial (CCP) (EC 1.11.1.5)" cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302] chloroplast [GO:0009507]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759] cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601] GO:0000302; GO:0004130; GO:0004601; GO:0005758; GO:0005759; GO:0009507; GO:0020037; GO:0034599; GO:0042744; GO:0046872 reviewed Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus) 71 TRINITY_DN312006_c1_g5 -11.74636701 8.460980218 13.1439879 0.000981429 0.016118081 Q58A42 TRINITY_DN312006_c1_g5_i1 4.30E-121 Protein DD3-3 integral component of membrane [GO:0016021] GO:0016021 reviewed Dictyostelium discoideum (Slime mold) 72 TRINITY_DN312093_c0_g3 22.24464612 12.26004776 123.1893943 8.08E-12 7.09E-10 Q2M5E4 TRINITY_DN312093_c0_g3_i1 3.90E-10 Regulator of G-protein signaling 21 (RGS21) G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968] plasma membrane [GO:0005886] GTPase activity [GO:0003924] GO:0003924; GO:0005886; GO:0007186; GO:0009968 reviewed Homo sapiens (Human) 73 TRINITY_DN312701_c0_g2 16.97230683 10.82614004 58.0219398 1.29E-08 4.25E-07 Q9HC07 TRINITY_DN312701_c0_g2_i1 9.00E-09 Transmembrane protein 165 (Transmembrane protein PT27) (Transmembrane protein TPARL) cellular calcium ion homeostasis [GO:0006874]; Golgi calcium ion transport [GO:0032472]; protein N-linked glycosylation [GO:0006487]; regulation of lysosomal lumen pH [GO:0035751] early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; trans-Golgi network membrane [GO:0032588] GO:0005765; GO:0005794; GO:0006487; GO:0006874; GO:0010008; GO:0016021; GO:0031901; GO:0031902; GO:0032472; GO:0032588; GO:0035751; GO:0043231 reviewed Homo sapiens (Human) 74 TRINITY_DN312701_c0_g3 17.81120991 12.23120407 84.2138572 9.28E-11 4.40E-09 Q93Y38 TRINITY_DN312701_c0_g3_i1 3.00E-21 GDT1-like protein 3 Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021] GO:0005794; GO:0016021 reviewed Arabidopsis thaliana (Mouse-ear cress) 75 TRINITY_DN312702_c0_g1 13.69689136 8.661179046 17.91618933 0.000220763 0.004418701 Q0DB53 TRINITY_DN312702_c0_g1_i3 1.40E-06 DEAD-box ATP-dependent RNA helicase 52A (EC 3.6.4.13) ATP binding [GO:0005524]; helicase activity [GO:0004386]; RNA binding [GO:0003723] GO:0003723; GO:0004386; GO:0005524 reviewed Oryza sativa subsp. japonica (Rice) 76 TRINITY_DN312722_c5_g1 -6.211857714 10.59374475 14.96476803 0.000466856 0.008306152 P23324 TRINITY_DN312722_c5_g1_i6 9.50E-06 Polyubiquitin [Cleaved into: Ubiquitin] cytoplasm [GO:0005737]; nucleus [GO:0005634] GO:0005634; GO:0005737 reviewed Euplotes eurystomus (Ciliate) 77 TRINITY_DN312726_c1_g4 19.49740552 15.24884959 100.7679884 9.64E-12 7.72E-10 P51906 TRINITY_DN312726_c1_g4_i1 4.30E-48 Excitatory amino acid transporter 3 (Excitatory amino-acid carrier 1) (Sodium-dependent glutamate/aspartate transporter 3) (Solute carrier family 1 member 1) chloride transmembrane transport [GO:1902476]; cysteine transmembrane transport [GO:1903712]; cysteine transport [GO:0042883]; D-aspartate import across plasma membrane [GO:0070779]; L-aspartate import across plasma membrane [GO:0140009]; L-glutamate import [GO:0051938]; L-glutamate import across plasma membrane [GO:0098712]; L-glutamate transmembrane transport [GO:0015813]; positive regulation of heart rate [GO:0010460]; protein homooligomerization [GO:0051260] apical plasma membrane [GO:0016324]; early endosome membrane [GO:0031901]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038] chloride transmembrane transporter activity [GO:0015108]; cysteine transmembrane transporter activity [GO:0033229]; glutamate:sodium symporter activity [GO:0015501]; glutamate binding [GO:0016595]; high-affinity glutamate transmembrane transporter activity [GO:0005314]; L-glutamate transmembrane transporter activity [GO:0005313]; metal ion binding [GO:0046872] GO:0005313; GO:0005314; GO:0005886; GO:0005887; GO:0010460; GO:0015108; GO:0015501; GO:0015813; GO:0016020; GO:0016324; GO:0016595; GO:0031901; GO:0033229; GO:0042883; GO:0046872; GO:0051260; GO:0051938; GO:0055038; GO:0070779; GO:0098712; GO:0140009; GO:1902476; GO:1903712 reviewed Mus musculus (Mouse) 78 TRINITY_DN312737_c1_g1 22.74767972 13.85165927 127.8846073 1.39E-12 6.02E-10 P52504 TRINITY_DN312737_c1_g1_i1 1.50E-08 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (Complex I-13kD-A) (CI-13kD-A) (NADH-ubiquinone oxidoreductase 13 kDa-A subunit)" "mitochondrial electron transport, NADH to ubiquinone [GO:0006120]" mitochondrial respiratory chain complex I [GO:0005747] GO:0005747; GO:0006120 reviewed Rattus norvegicus (Rat) 79 TRINITY_DN312737_c2_g2 16.51602456 9.764168498 40.38062098 6.77E-07 2.02E-05 Q8K3E5 TRINITY_DN312737_c2_g2_i1 2.60E-07 Jouberin (Abelson helper integration site 1 protein) (AHI-1) cellular protein localization [GO:0034613]; central nervous system development [GO:0007417]; cilium assembly [GO:0060271]; cloaca development [GO:0035844]; eye photoreceptor cell development [GO:0042462]; heart looping [GO:0001947]; hindbrain development [GO:0030902]; Kupffer's vesicle development [GO:0070121]; left/right axis specification [GO:0070986]; morphogenesis of a polarized epithelium [GO:0001738]; negative regulation of apoptotic process [GO:0043066]; negative regulation of glucose import [GO:0046325]; non-motile cilium assembly [GO:1905515]; otic vesicle development [GO:0071599]; photoreceptor cell outer segment organization [GO:0035845]; positive regulation of gene expression [GO:0010628]; positive regulation of growth [GO:0045927]; positive regulation of neuron projection development [GO:0010976]; positive regulation of polarized epithelial cell differentiation [GO:0030862]; positive regulation of receptor internalization [GO:0002092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; pronephric duct morphogenesis [GO:0039023]; pronephric nephron tubule morphogenesis [GO:0039008]; protein localization to organelle [GO:0033365]; regulation of behavior [GO:0050795]; regulation of protein secretion [GO:0050708]; retina development in camera-type eye [GO:0060041]; retina layer formation [GO:0010842]; retinal cone cell development [GO:0046549]; retinal rod cell development [GO:0046548]; specification of axis polarity [GO:0065001]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vesicle-mediated transport [GO:0016192]; vesicle targeting [GO:0006903] adherens junction [GO:0005912]; cell-cell junction [GO:0005911]; centriole [GO:0005814]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; cilium [GO:0005929]; cytoplasm [GO:0005737]; MKS complex [GO:0036038]; non-motile cilium [GO:0097730]; photoreceptor outer segment [GO:0001750] identical protein binding [GO:0042802] GO:0001738; GO:0001750; GO:0001947; GO:0002092; GO:0005737; GO:0005813; GO:0005814; GO:0005911; GO:0005912; GO:0005929; GO:0006903; GO:0007169; GO:0007417; GO:0010628; GO:0010842; GO:0010976; GO:0016192; GO:0030862; GO:0030902; GO:0033365; GO:0034613; GO:0035844; GO:0035845; GO:0036038; GO:0036064; GO:0039008; GO:0039023; GO:0042462; GO:0042802; GO:0043066; GO:0045927; GO:0045944; GO:0046325; GO:0046548; GO:0046549; GO:0050708; GO:0050795; GO:0060041; GO:0060271; GO:0065001; GO:0070121; GO:0070986; GO:0071599; GO:0097730; GO:1905515 reviewed Mus musculus (Mouse) 80 TRINITY_DN314232_c4_g4 -9.57218931 7.936025538 12.29167705 0.001359688 0.020985062 Q9UR07 TRINITY_DN314232_c4_g4_i1 2.80E-27 Transposon Tf2-11 polyprotein (Retrotransposable element Tf2 155 kDa protein) DNA integration [GO:0015074]; DNA recombination [GO:0006310] nucleus [GO:0005634] aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0015074; GO:0046872 reviewed Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) 81 TRINITY_DN314258_c2_g2 -6.985995006 10.08923859 11.96321401 0.001468935 0.021880292 Q9ZT94 TRINITY_DN314258_c2_g2_i1 5.60E-23 Retrovirus-related Pol polyprotein from transposon RE2 (Retro element 2) (AtRE2) [Includes: Protease RE2 (EC 3.4.23.-); Reverse transcriptase RE2 (EC 2.7.7.49); Endonuclease RE2] DNA integration [GO:0015074]; DNA recombination [GO:0006310] retrotransposon nucleocapsid [GO:0000943] aspartic-type endopeptidase activity [GO:0004190]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; RNA-directed DNA polymerase activity [GO:0003964] GO:0000943; GO:0003676; GO:0003964; GO:0004190; GO:0004519; GO:0006310; GO:0015074; GO:0046872 reviewed Arabidopsis thaliana (Mouse-ear cress) 82 TRINITY_DN314271_c0_g1 18.31552718 11.07072249 81.16131929 3.35E-10 1.36E-08 Q949G5 TRINITY_DN314271_c0_g1_i1 1.60E-06 MOB kinase activator-like 1A (Mob1 homolog 1A) (Mps one binder kinase activator-like 1A) (MsMob1-1) (MsMob1-2) (MsMob1-3) (MsMob1-A) cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phragmoplast [GO:0009524] metal ion binding [GO:0046872] GO:0005737; GO:0005856; GO:0009524; GO:0046872 reviewed Medicago sativa subsp. falcata (Sickle medic) (Medicago falcata) 83 TRINITY_DN314271_c1_g1 14.52432827 9.29812505 32.06826656 3.11E-06 7.98E-05 P04146 TRINITY_DN314271_c1_g1_i3 2.50E-37 Copia protein (Gag-int-pol protein) [Cleaved into: Copia VLP protein; Copia protease (EC 3.4.23.-)] DNA integration [GO:0015074] retrotransposon nucleocapsid [GO:0000943] aspartic-type endopeptidase activity [GO:0004190]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]; zinc ion binding [GO:0008270] GO:0000943; GO:0003676; GO:0004190; GO:0005524; GO:0008270; GO:0015074 reviewed Drosophila melanogaster (Fruit fly) 84 TRINITY_DN314627_c5_g1 -6.399750047 10.31708471 11.01619761 0.002149105 0.029923948 P10978 TRINITY_DN314627_c5_g1_i2 1.70E-08 Retrovirus-related Pol polyprotein from transposon TNT 1-94 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] DNA integration [GO:0015074] retrotransposon nucleocapsid [GO:0000943] aspartic-type endopeptidase activity [GO:0004190]; endonuclease activity [GO:0004519]; nucleic acid binding [GO:0003676]; RNA-directed DNA polymerase activity [GO:0003964]; zinc ion binding [GO:0008270] GO:0000943; GO:0003676; GO:0003964; GO:0004190; GO:0004519; GO:0008270; GO:0015074 reviewed Nicotiana tabacum (Common tobacco) 85 TRINITY_DN314629_c1_g3 -11.54037028 8.780989075 17.78551047 0.000196197 0.00398934 Q94HW2 TRINITY_DN314629_c1_g3_i1 1.40E-43 Retrovirus-related Pol polyprotein from transposon RE1 (Retro element 1) (AtRE1) [Includes: Protease RE1 (EC 3.4.23.-); Reverse transcriptase RE1 (EC 2.7.7.49); Endonuclease RE1] DNA integration [GO:0015074]; DNA recombination [GO:0006310] retrotransposon nucleocapsid [GO:0000943] aspartic-type endopeptidase activity [GO:0004190]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; RNA-directed DNA polymerase activity [GO:0003964] GO:0000943; GO:0003676; GO:0003964; GO:0004190; GO:0004519; GO:0006310; GO:0015074; GO:0046872 reviewed Arabidopsis thaliana (Mouse-ear cress) 86 TRINITY_DN314831_c1_g5 9.563815728 7.059218481 13.16543414 0.001114917 0.01763221 A8XDJ2 TRINITY_DN314831_c1_g5_i1 2.00E-12 Ubiquitin thioesterase otubain-like (EC 3.4.19.12) (Deubiquitinating enzyme otubain-like) (Ubiquitin-specific-processing protease otubain-like) protein K48-linked deubiquitination [GO:0071108] nucleus [GO:0005634] NEDD8-specific protease activity [GO:0019784]; thiol-dependent ubiquitin-specific protease activity [GO:0004843]; ubiquitin binding [GO:0043130] GO:0004843; GO:0005634; GO:0019784; GO:0043130; GO:0071108 reviewed Caenorhabditis briggsae 87 TRINITY_DN314888_c2_g4 -10.44624634 10.36853735 23.40365715 2.74E-05 0.000604181 Q94HW2 TRINITY_DN314888_c2_g4_i1 3.70E-133 Retrovirus-related Pol polyprotein from transposon RE1 (Retro element 1) (AtRE1) [Includes: Protease RE1 (EC 3.4.23.-); Reverse transcriptase RE1 (EC 2.7.7.49); Endonuclease RE1] DNA integration [GO:0015074]; DNA recombination [GO:0006310] retrotransposon nucleocapsid [GO:0000943] aspartic-type endopeptidase activity [GO:0004190]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; RNA-directed DNA polymerase activity [GO:0003964] GO:0000943; GO:0003676; GO:0003964; GO:0004190; GO:0004519; GO:0006310; GO:0015074; GO:0046872 reviewed Arabidopsis thaliana (Mouse-ear cress) 88 TRINITY_DN316234_c0_g1 8.652953447 10.81469926 16.82655359 0.00023875 0.004705212 Q00645 TRINITY_DN316234_c0_g1_i1 1.10E-06 Pectate lyase plyB (EC 4.2.2.2) cell wall organization [GO:0071555]; pectin catabolic process [GO:0045490] extracellular region [GO:0005576] metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570] GO:0005576; GO:0030570; GO:0045490; GO:0046872; GO:0071555 reviewed Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) 89 TRINITY_DN316237_c1_g2 -5.344180192 12.06777552 16.46476539 0.000271379 0.005188596 Q94HW2 TRINITY_DN316237_c1_g2_i5 1.50E-53 Retrovirus-related Pol polyprotein from transposon RE1 (Retro element 1) (AtRE1) [Includes: Protease RE1 (EC 3.4.23.-); Reverse transcriptase RE1 (EC 2.7.7.49); Endonuclease RE1] DNA integration [GO:0015074]; DNA recombination [GO:0006310] retrotransposon nucleocapsid [GO:0000943] aspartic-type endopeptidase activity [GO:0004190]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; RNA-directed DNA polymerase activity [GO:0003964] GO:0000943; GO:0003676; GO:0003964; GO:0004190; GO:0004519; GO:0006310; GO:0015074; GO:0046872 reviewed Arabidopsis thaliana (Mouse-ear cress) 90 TRINITY_DN316900_c0_g1 17.34857455 9.830848518 44.34658904 3.01E-07 9.18E-06 Q03168 TRINITY_DN316900_c0_g1_i5 3.60E-10 Lysosomal aspartic protease (EC 3.4.23.-) lysosome [GO:0005764] aspartic-type endopeptidase activity [GO:0004190] GO:0004190; GO:0005764 reviewed Aedes aegypti (Yellowfever mosquito) (Culex aegypti) 91 TRINITY_DN316936_c6_g6 -8.294308142 9.509645519 12.07703171 0.001404182 0.021271833 P10978 TRINITY_DN316936_c6_g6_i1 1.10E-86 Retrovirus-related Pol polyprotein from transposon TNT 1-94 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] DNA integration [GO:0015074] retrotransposon nucleocapsid [GO:0000943] aspartic-type endopeptidase activity [GO:0004190]; endonuclease activity [GO:0004519]; nucleic acid binding [GO:0003676]; RNA-directed DNA polymerase activity [GO:0003964]; zinc ion binding [GO:0008270] GO:0000943; GO:0003676; GO:0003964; GO:0004190; GO:0004519; GO:0008270; GO:0015074 reviewed Nicotiana tabacum (Common tobacco) 92 TRINITY_DN317247_c5_g1 -5.135485344 12.41473518 15.06273278 0.000450344 0.008125215 P10978 TRINITY_DN317247_c5_g1_i1 1.20E-29 Retrovirus-related Pol polyprotein from transposon TNT 1-94 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] DNA integration [GO:0015074] retrotransposon nucleocapsid [GO:0000943] aspartic-type endopeptidase activity [GO:0004190]; endonuclease activity [GO:0004519]; nucleic acid binding [GO:0003676]; RNA-directed DNA polymerase activity [GO:0003964]; zinc ion binding [GO:0008270] GO:0000943; GO:0003676; GO:0003964; GO:0004190; GO:0004519; GO:0008270; GO:0015074 reviewed Nicotiana tabacum (Common tobacco) 93 TRINITY_DN317297_c1_g3 15.79094956 9.128840514 36.19880689 1.68E-06 4.58E-05 Q9P2K9 TRINITY_DN317297_c1_g3_i3 4.90E-10 Protein dispatched homolog 3 (Patched domain-containing protein 2) cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of neural precursor cell proliferation [GO:2000179]; regulation of lipid transport [GO:0032368]; smoothened signaling pathway [GO:0007224] cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; nuclear membrane [GO:0031965] GO:0005737; GO:0005783; GO:0005789; GO:0007224; GO:0008203; GO:0016021; GO:0030659; GO:0031965; GO:0032368; GO:0042632; GO:0045665; GO:0045834; GO:2000179 reviewed Homo sapiens (Human) 94 TRINITY_DN317297_c2_g1 21.33990163 12.54171776 122.0424258 2.51E-12 6.02E-10 A0A0D3QS97 TRINITY_DN317297_c2_g1_i3 1.10E-06 Palmitoleoyl-protein carboxylesterase notum2 (EC 3.1.1.98) Wnt signaling pathway [GO:0016055] extracellular region [GO:0005576] carboxylic ester hydrolase activity [GO:0052689] GO:0005576; GO:0016055; GO:0052689 reviewed Xenopus laevis (African clawed frog) 95 TRINITY_DN384783_c0_g1 11.15855281 7.408287438 17.12886196 0.000284888 0.005366791 P55567 TRINITY_DN384783_c0_g1_i1 2.90E-12 Uncharacterized protein y4mH hydrolase activity [GO:0016787] GO:0016787 reviewed Sinorhizobium fredii (strain NBRC 101917 / NGR234) 96 TRINITY_DN449830_c0_g1 9.642015125 7.063410062 13.46867926 0.000999184 0.01620196 Q8IVF4 TRINITY_DN449830_c0_g1_i1 4.00E-65 "Dynein heavy chain 10, axonemal (Axonemal beta dynein heavy chain 10) (Ciliary dynein heavy chain 10)" microtubule-based movement [GO:0007018] axoneme [GO:0005930]; dynein complex [GO:0030286]; microtubule [GO:0005874] "ATP binding [GO:0005524]; ATP-dependent microtubule motor activity, minus-end-directed [GO:0008569]; dynein intermediate chain binding [GO:0045505]; dynein light chain binding [GO:0045503]; dynein light intermediate chain binding [GO:0051959]" GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0045503; GO:0045505; GO:0051959 reviewed Homo sapiens (Human) 97 TRINITY_DN52678_c0_g1 8.72647247 6.924226495 11.44808219 0.0021125 0.029737497 P08262 TRINITY_DN52678_c0_g1_i1 7.10E-13 5-aminolevulinate synthase (EC 2.3.1.37) (5-aminolevulinic acid synthase) (Delta-ALA synthase) (Delta-aminolevulinate synthase) protoporphyrinogen IX biosynthetic process [GO:0006782] 5-aminolevulinate synthase activity [GO:0003870]; pyridoxal phosphate binding [GO:0030170] GO:0003870; GO:0006782; GO:0030170 reviewed Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110) 98 TRINITY_DN54630_c0_g1 7.214400847 6.55812138 10.57233156 0.002964546 0.039455514 Q9FKP1 TRINITY_DN54630_c0_g1_i1 2.00E-06 Cation/calcium exchanger 1 (AtCCX1) (Protein CATION EXCHANGER 7) potassium ion transport [GO:0006813]; sodium ion transport [GO:0006814] integral component of membrane [GO:0016021]; vacuolar membrane [GO:0005774] antiporter activity [GO:0015297] GO:0005774; GO:0006813; GO:0006814; GO:0015297; GO:0016021 reviewed Arabidopsis thaliana (Mouse-ear cress) 99 TRINITY_DN54639_c0_g1 7.577527561 6.644372458 10.22324726 0.003402217 0.04402263 P92519 TRINITY_DN54639_c0_g1_i1 3.30E-21 Uncharacterized mitochondrial protein AtMg00810 (ORF240b) mitochondrion [GO:0005739]; retrotransposon nucleocapsid [GO:0000943] GO:0000943; GO:0005739 reviewed Arabidopsis thaliana (Mouse-ear cress) 100 TRINITY_DN66609_c0_g1 8.716100321 6.799184942 11.97994361 0.001727159 0.024859449 Q0V6M5 TRINITY_DN66609_c0_g1_i1 2.50E-09 Bifunctional lycopene cyclase/phytoene synthase [Includes: Lycopene beta-cyclase (EC 5.5.1.19) (Lycopene cyclase); Phytoene synthase (EC 2.5.1.32)] carotenoid biosynthetic process [GO:0016117]; ergosterol biosynthetic process [GO:0006696] integral component of membrane [GO:0016021] farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; geranylgeranyl-diphosphate geranylgeranyltransferase activity [GO:0016767]; intramolecular lyase activity [GO:0016872]; squalene synthase activity [GO:0051996] GO:0004310; GO:0006696; GO:0016021; GO:0016117; GO:0016767; GO:0016872; GO:0051996 reviewed Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Parastagonospora nodorum)