ID Gene Name Species BIOCARTA COG_ONTOLOGY GOTERM_BP_DIRECT GOTERM_CC_DIRECT GOTERM_MF_DIRECT INTERPRO KEGG_PATHWAY OMIM_DISEASE PIR_SUPERFAMILY SMART UP_KEYWORDS UP_SEQ_FEATURE A6H184 30S ribosomal protein S15(rpsO) Flavobacterium psychrophilum JIP02/86 GO:0006412~translation, GO:0005840~ribosome, GO:0003735~structural constituent of ribosome,GO:0019843~rRNA binding, IPR000589:Ribosomal protein S15,IPR005290:Ribosomal protein S15, bacterial-type,IPR009068:S15/NS1, RNA-binding, fps03010:Ribosome, SM01387:SM01387, Complete proteome,Reference proteome,Ribonucleoprotein,Ribosomal protein,RNA-binding,rRNA-binding, chain:30S ribosomal protein S15, Q1EHB3 ADAM metallopeptidase with thrombospondin type 1 motif, 7(Adamts7) Rattus norvegicus GO:0006508~proteolysis,GO:0032331~negative regulation of chondrocyte differentiation,GO:0051603~proteolysis involved in cellular protein catabolic process,GO:0071347~cellular response to interleukin-1,GO:0071356~cellular response to tumor necrosis factor,GO:0071773~cellular response to BMP stimulus,GO:0098779~mitophagy in response to mitochondrial depolarization, GO:0005578~proteinaceous extracellular matrix,GO:0009986~cell surface, GO:0004222~metalloendopeptidase activity,GO:0008237~metallopeptidase activity,GO:0008270~zinc ion binding, IPR000884:Thrombospondin, type 1 repeat,IPR001590:Peptidase M12B, ADAM/reprolysin,IPR002870:Peptidase M12B, propeptide,IPR010294:ADAM-TS Spacer 1,IPR010909:PLAC,IPR013273:Peptidase M12B, ADAM-TS,IPR024079:Metallopeptidase, catalytic domain, SM00209:TSP1, Alternative splicing,Cleavage on pair of basic residues,Complete proteome,Disulfide bond,Extracellular matrix,Glycoprotein,Hydrolase,Metal-binding,Metalloprotease,Protease,Proteoglycan,Reference proteome,Repeat,Secreted,Signal, chain:A disintegrin and metalloproteinase with thrombospondin motifs 7,compositionally biased region:Cys-rich,disulfide bond,domain:Disintegrin,domain:Peptidase M12B,domain:PLAC,domain:TSP type-1 1,domain:TSP type-1 2,domain:TSP type-1 3,domain:TSP type-1 4,domain:TSP type-1 5,domain:TSP type-1 6,domain:TSP type-1 7,domain:TSP type-1 8,glycosylation site:N-linked (GlcNAc...),metal ion-binding site:Zinc; catalytic,metal ion-binding site:Zinc; in inhibited form,region of interest:Spacer,short sequence motif:Cysteine switch,signal peptide,splice variant, Q969Q4 ADP ribosylation factor like GTPase 11(ARL11) Homo sapiens GO:0002244~hematopoietic progenitor cell differentiation,GO:0007264~small GTPase mediated signal transduction, GO:0005622~intracellular, GO:0005515~protein binding,GO:0005525~GTP binding, IPR005225:Small GTP-binding protein domain,IPR006689:Small GTPase superfamily, ARF/SAR type,IPR024156:Small GTPase superfamily, ARF type,IPR027417:P-loop containing nucleoside triphosphate hydrolase, Complete proteome,GTP-binding,Lipoprotein,Myristate,Nucleotide-binding,Polymorphism,Reference proteome, chain:ADP-ribosylation factor-like protein 11,lipid moiety-binding region:N-myristoyl glycine,modified residue,nucleotide phosphate-binding region:GTP,sequence variant, Q755N4 AFL221Cp(AGOS_AFL221C) Eremothecium gossypii ATCC 10895 GO:0000184~nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,GO:0006364~rRNA processing,GO:0010501~RNA secondary structure unwinding,GO:0071042~nuclear polyadenylation-dependent mRNA catabolic process,GO:1990120~messenger ribonucleoprotein complex assembly, GO:0005730~nucleolus,GO:0005739~mitochondrion,GO:0005829~cytosol, GO:0003723~RNA binding,GO:0004004~ATP-dependent RNA helicase activity,GO:0005524~ATP binding, IPR000629:RNA helicase, ATP-dependent, DEAD-box, conserved site,IPR001650:Helicase, C-terminal,IPR011545:DNA/RNA helicase, DEAD/DEAH box type, N-terminal,IPR014001:Helicase, superfamily 1/2, ATP-binding domain,IPR014014:RNA helicase, DEAD-box type, Q motif,IPR027417:P-loop containing nucleoside triphosphate hydrolase, ago03040:Spliceosome, SM00487:DEXDc,SM00490:HELICc, ATP-binding,Complete proteome,Cytoplasm,Helicase,Hydrolase,Nonsense-mediated mRNA decay,Nucleotide-binding,Nucleus,Reference proteome,Ribosome biogenesis,RNA-binding,rRNA processing, chain:ATP-dependent RNA helicase dbp2,domain:Helicase ATP-binding,domain:Helicase C-terminal,nucleotide phosphate-binding region:ATP,region of interest:RNA-binding RGG-box,short sequence motif:DEAD box,short sequence motif:Q motif, Q0V9S3 CBP80/20-dependent translation initiation factor(ctif) Xenopus tropicalis GO:0000184~nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,GO:0006446~regulation of translational initiation, GO:0048471~perinuclear region of cytoplasm, GO:0003723~RNA binding, IPR003890:MIF4G-like, type 3,IPR016021:MIF4-like, type 1/2/3,IPR016024:Armadillo-type fold, SM00543:MIF4G, Complete proteome,Cytoplasm,Nonsense-mediated mRNA decay,Reference proteome,Translation regulation, chain:CBP80/20-dependent translation initiation factor,domain:MIF4G, Q8I8U7 CG33554 gene product from transcript CG33554-RE(Nipped-A) Drosophila melanogaster GO:0000281~mitotic cytokinesis,GO:0006281~DNA repair,GO:0006351~transcription, DNA-templated,GO:0006355~regulation of transcription, DNA-templated,GO:0006909~phagocytosis,GO:0016573~histone acetylation,GO:0035222~wing disc pattern formation,GO:0043486~histone exchange,GO:0043966~histone H3 acetylation,GO:0045747~positive regulation of Notch signaling pathway, GO:0000123~histone acetyltransferase complex,GO:0000124~SAGA complex,GO:0005634~nucleus,GO:0005700~polytene chromosome,GO:0005703~polytene chromosome puff,GO:0005737~cytoplasm,GO:0005875~microtubule associated complex,GO:0035267~NuA4 histone acetyltransferase complex, GO:0004402~histone acetyltransferase activity,GO:0016301~kinase activity, IPR000403:Phosphatidylinositol 3-/4-kinase, catalytic domain,IPR003151:PIK-related kinase, FAT,IPR003152:PIK-related kinase, FATC,IPR011009:Protein kinase-like domain,IPR011989:Armadillo-like helical,IPR011990:Tetratricopeptide-like helical,IPR014009:PIK-related kinase,IPR016024:Armadillo-type fold, SM00146:PI3Kc,SM01343:SM01343, Activator,Acyltransferase,Chromatin regulator,Complete proteome,Nucleus,Proteomics identification,Reference proteome,Repeat,Transcription,Transcription regulation,Transferase, chain:Transcription-associated protein 1,domain:FAT,domain:FATC,domain:PI3K/PI4K,repeat:HEAT 1,repeat:HEAT 2,repeat:HEAT 3,repeat:HEAT 4,repeat:HEAT 5,repeat:HEAT 6,sequence conflict, Q9P0U4 CXXC finger protein 1(CXXC1) Homo sapiens GO:0006351~transcription, DNA-templated,GO:0006355~regulation of transcription, DNA-templated,GO:0036498~IRE1-mediated unfolded protein response,GO:0045893~positive regulation of transcription, DNA-templated,GO:0051568~histone H3-K4 methylation, GO:0005634~nucleus,GO:0005654~nucleoplasm,GO:0005737~cytoplasm,GO:0016363~nuclear matrix,GO:0016607~nuclear speck,GO:0035097~histone methyltransferase complex,GO:0048188~Set1C/COMPASS complex, GO:0000987~core promoter proximal region sequence-specific DNA binding,GO:0003677~DNA binding,GO:0005515~protein binding,GO:0008270~zinc ion binding,GO:0042800~histone methyltransferase activity (H3-K4 specific),GO:0045322~unmethylated CpG binding, IPR001965:Zinc finger, PHD-type,IPR002857:Zinc finger, CXXC-type,IPR011011:Zinc finger, FYVE/PHD-type,IPR013083:Zinc finger, RING/FYVE/PHD-type,IPR019786:Zinc finger, PHD-type, conserved site,IPR019787:Zinc finger, PHD-finger,IPR022056:CpG binding protein, C-terminal, SM00249:PHD, 3D-structure,Acetylation,Activator,Alternative splicing,Coiled coil,Complete proteome,DNA-binding,Isopeptide bond,Metal-binding,Nucleus,Phosphoprotein,Proteomics identification,Reference proteome,Transcription,Transcription regulation,Ubl conjugation,Zinc,Zinc-finger, chain:CpG-binding protein,compositionally biased region:Arg/Lys-rich (basic),compositionally biased region:Asp/Glu-rich (acidic),modified residue,mutagenesis site,sequence conflict,zinc finger region:CXXC-type,zinc finger region:PHD-type, Q60452 ERCC excision repair 2, TFIIH core complex helicase subunit(Ercc2) Cricetulus griseus GO:0006283~transcription-coupled nucleotide-excision repair,GO:0006366~transcription from RNA polymerase II promoter,GO:0006468~protein phosphorylation,GO:0006915~apoptotic process,GO:0006979~response to oxidative stress,GO:0007059~chromosome segregation,GO:0033683~nucleotide-excision repair, DNA incision,GO:0035315~hair cell differentiation,GO:0045893~positive regulation of transcription, DNA-templated,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,GO:1901990~regulation of mitotic cell cycle phase transition, GO:0005675~holo TFIIH complex,GO:0005737~cytoplasm,GO:0005819~spindle,GO:0071817~MMXD complex, GO:0003677~DNA binding,GO:0004003~ATP-dependent DNA helicase activity,GO:0005524~ATP binding,GO:0008022~protein C-terminus binding,GO:0043139~5'-3' DNA helicase activity,GO:0046872~metal ion binding,GO:0047485~protein N-terminus binding,GO:0051539~4 iron, 4 sulfur cluster binding, IPR001945:Xeroderma pigmentosum group D protein,IPR002464:DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site,IPR006554:Helicase-like, DEXD box c2 type,IPR006555:ATP-dependent helicase, C-terminal,IPR010614:DEAD2,IPR010643:Domain of unknown function DUF1227,IPR013020:DNA helicase (DNA repair), Rad3 type,IPR014013:Helicase, superfamily 1/2, ATP-binding domain, DinG/Rad3-type,IPR027417:P-loop containing nucleoside triphosphate hydrolase, cge03022:Basal transcription factors,cge03420:Nucleotide excision repair, SM00488:DEXDc2,SM00491:HELICc2, 4Fe-4S,ATP-binding,Chromosome partition,Cytoplasm,Cytoskeleton,DNA damage,DNA repair,DNA-binding,Helicase,Hydrolase,Iron,Iron-sulfur,Magnesium,Metal-binding,Nucleotide-binding,Nucleus,Polymorphism,Transcription,Transcription regulation,Ubl conjugation, Q03468 ERCC excision repair 6, chromatin remodeling factor(ERCC6) Homo sapiens GO:0000303~response to superoxide,GO:0006283~transcription-coupled nucleotide-excision repair,GO:0006284~base-excision repair,GO:0006290~pyrimidine dimer repair,GO:0006362~transcription elongation from RNA polymerase I promoter,GO:0006366~transcription from RNA polymerase II promoter,GO:0006979~response to oxidative stress,GO:0007256~activation of JNKK activity,GO:0007257~activation of JUN kinase activity,GO:0008630~intrinsic apoptotic signaling pathway in response to DNA damage,GO:0009411~response to UV,GO:0009636~response to toxic substance,GO:0010165~response to X-ray,GO:0010224~response to UV-B,GO:0010332~response to gamma radiation,GO:0032784~regulation of DNA-templated transcription, elongation,GO:0032786~positive regulation of DNA-templated transcription, elongation,GO:0035264~multicellular organism growth,GO:0045494~photoreceptor cell maintenance,GO:0045815~positive regulation of gene expression, epigenetic,GO:0061098~positive regulation of protein tyrosine kinase activity, GO:0005634~nucleus,GO:0005654~nucleoplasm,GO:0005730~nucleolus,GO:0008023~transcription elongation factor complex, GO:0003677~DNA binding,GO:0003678~DNA helicase activity,GO:0003682~chromatin binding,GO:0004386~helicase activity,GO:0005515~protein binding,GO:0005524~ATP binding,GO:0008022~protein C-terminus binding,GO:0008094~DNA-dependent ATPase activity,GO:0030296~protein tyrosine kinase activator activity,GO:0032403~protein complex binding,GO:0047485~protein N-terminus binding, IPR000330:SNF2-related,IPR001650:Helicase, C-terminal,IPR014001:Helicase, superfamily 1/2, ATP-binding domain,IPR027417:P-loop containing nucleoside triphosphate hydrolase, hsa03420:Nucleotide excision repair, 133540~Cockayne syndrome, type B,211980~Lung cancer, susceptibility to,214150~Cerebrooculofacioskeletal syndrome 1,278800~De Sanctis-Cacchione syndrome,600630~UV-sensitive syndrome 1,613761~Macular degeneration, age-related, susceptibility to 5, SM00487:DEXDc,SM00490:HELICc, 3D-structure,Age-related macular degeneration,ATP-binding,Cataract,Cockayne syndrome,Complete proteome,Deafness,Disease mutation,DNA damage,DNA repair,DNA-binding,Dwarfism,Helicase,Hydrolase,Mental retardation,Methylation,Nucleotide-binding,Nucleus,Phosphoprotein,Polymorphism,Proteomics identification,Reference proteome,Transcription,Transcription regulation,Ubl conjugation,Xeroderma pigmentosum, chain:DNA excision repair protein ERCC-6,compositionally biased region:Asp/Glu-rich (acidic),compositionally biased region:Gly-rich,domain:Helicase ATP-binding,domain:Helicase C-terminal,modified residue,nucleotide phosphate-binding region:ATP,sequence variant,short sequence motif:DEGH box,short sequence motif:Nuclear localization signal, Q8BH16 F-box and leucine-rich repeat protein 2(Fbxl2) Mus musculus GO:0006511~ubiquitin-dependent protein catabolic process,GO:0006513~protein monoubiquitination,GO:0010506~regulation of autophagy,GO:0014066~regulation of phosphatidylinositol 3-kinase signaling,GO:0016567~protein ubiquitination,GO:0031146~SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, GO:0016020~membrane,GO:0019005~SCF ubiquitin ligase complex, GO:0004842~ubiquitin-protein transferase activity,GO:0005515~protein binding,GO:0005516~calmodulin binding,GO:0019903~protein phosphatase binding,GO:0036312~phosphatidylinositol 3-kinase regulatory subunit binding, IPR001611:Leucine-rich repeat,IPR001810:F-box domain, cyclin-like,IPR006553:Leucine-rich repeat, cysteine-containing subtype, SM00256:FBOX,SM00367:LRR_CC, Calcium,Calmodulin-binding,Complete proteome,Leucine-rich repeat,Lipoprotein,Membrane,Prenylation,Reference proteome,Repeat,Ubl conjugation pathway, chain:F-box/LRR-repeat protein 2,domain:F-box,repeat:LRR 1,repeat:LRR 10,repeat:LRR 11,repeat:LRR 2,repeat:LRR 3,repeat:LRR 4,repeat:LRR 5,repeat:LRR 6,repeat:LRR 7,repeat:LRR 8,repeat:LRR 9,sequence conflict, Q6V0I7 FAT atypical cadherin 4(FAT4) Homo sapiens GO:0001658~branching involved in ureteric bud morphogenesis,GO:0003007~heart morphogenesis,GO:0007009~plasma membrane organization,GO:0007156~homophilic cell adhesion via plasma membrane adhesion molecules,GO:0007157~heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules,GO:0007219~Notch signaling pathway,GO:0008543~fibroblast growth factor receptor signaling pathway,GO:0021987~cerebral cortex development,GO:0022008~neurogenesis,GO:0035329~hippo signaling,GO:0043931~ossification involved in bone maturation,GO:0048565~digestive tract development,GO:0060122~inner ear receptor stereocilium organization,GO:0072137~condensed mesenchymal cell proliferation,GO:0072307~regulation of metanephric nephron tubule epithelial cell differentiation, GO:0005622~intracellular,GO:0005886~plasma membrane,GO:0016020~membrane,GO:0016021~integral component of membrane,GO:0045177~apical part of cell,GO:0070062~extracellular exosome, GO:0005509~calcium ion binding,GO:0005515~protein binding, IPR000152:EGF-type aspartate/asparagine hydroxylation site,IPR000742:Epidermal growth factor-like domain,IPR001791:Laminin G domain,IPR001881:EGF-like calcium-binding,IPR002126:Cadherin,IPR009030:Insulin-like growth factor binding protein, N-terminal,IPR013032:EGF-like, conserved site,IPR013320:Concanavalin A-like lectin/glucanase, subgroup,IPR015919:Cadherin-like,IPR018097:EGF-like calcium-binding, conserved site,IPR020894:Cadherin conserved site, 615546~Van Maldergem syndrome 2,616006~Hennekam lymphangiectasia-lymphedema syndrome 2, SM00112:CA,SM00179:EGF_CA,SM00181:EGF,SM00282:LamG, Alternative splicing,Calcium,Cell adhesion,Complete proteome,Deafness,Disease mutation,Disulfide bond,EGF-like domain,Glycoprotein,Membrane,Mental retardation,Phosphoprotein,Polymorphism,Reference proteome,Repeat,Signal,Transmembrane,Transmembrane helix, chain:Protocadherin Fat 4,disulfide bond,domain:Cadherin 1,domain:Cadherin 10,domain:Cadherin 11,domain:Cadherin 12,domain:Cadherin 13,domain:Cadherin 14,domain:Cadherin 15,domain:Cadherin 16,domain:Cadherin 17,domain:Cadherin 18,domain:Cadherin 19,domain:Cadherin 2,domain:Cadherin 20,domain:Cadherin 21,domain:Cadherin 22,domain:Cadherin 23,domain:Cadherin 24,domain:Cadherin 25,domain:Cadherin 26,domain:Cadherin 27,domain:Cadherin 28,domain:Cadherin 29,domain:Cadherin 3,domain:Cadherin 30,domain:Cadherin 31,domain:Cadherin 32,domain:Cadherin 33,domain:Cadherin 34,domain:Cadherin 4,domain:Cadherin 5,domain:Cadherin 6,domain:Cadherin 7,domain:Cadherin 8,domain:Cadherin 9,domain:EGF-like 1,domain:EGF-like 2; calcium-binding,domain:EGF-like 3; calcium-binding,domain:EGF-like 4,domain:EGF-like 5,domain:EGF-like 6,domain:Laminin G-like 1,domain:Laminin G-like 2,glycosylation site:N-linked (GlcNAc...),modified residue,sequence conflict,sequence variant,signal peptide,splice variant,topological domain:Cytoplasmic,topological domain:Extracellular,transmembrane region, Q5SZK8 FRAS1 related extracellular matrix protein 2(FREM2) Homo sapiens GO:0002009~morphogenesis of an epithelium,GO:0007154~cell communication,GO:0007155~cell adhesion,GO:0007507~heart development,GO:0048839~inner ear development, GO:0005604~basement membrane,GO:0005886~plasma membrane,GO:0016021~integral component of membrane,GO:0070062~extracellular exosome, GO:0046872~metal ion binding, IPR003644:Na-Ca exchanger/integrin-beta4, 219000~Fraser syndrome, SM00237:Calx_beta, Alternative splicing,Calcium,Cell adhesion,Cell membrane,Complete proteome,Developmental protein,Disease mutation,Glycoprotein,Membrane,Metal-binding,Polymorphism,Reference proteome,Repeat,Signal,Transmembrane,Transmembrane helix, chain:FRAS1-related extracellular matrix protein 2,domain:Calx-beta 1,domain:Calx-beta 2,domain:Calx-beta 3,domain:Calx-beta 4,domain:Calx-beta 5,glycosylation site:N-linked (GlcNAc...),repeat:CSPG 1,repeat:CSPG 10,repeat:CSPG 11,repeat:CSPG 12,repeat:CSPG 2,repeat:CSPG 3,repeat:CSPG 4,repeat:CSPG 5,repeat:CSPG 6,repeat:CSPG 7,repeat:CSPG 8,repeat:CSPG 9,sequence conflict,sequence variant,signal peptide,splice variant,topological domain:Cytoplasmic,topological domain:Extracellular,transmembrane region, A2A870 Fas (TNFRSF6) binding factor 1(Fbf1) Mus musculus GO:0030030~cell projection organization,GO:0042384~cilium assembly,GO:0043297~apical junction assembly,GO:0060271~cilium morphogenesis,GO:0090162~establishment of epithelial cell polarity, GO:0000922~spindle pole,GO:0005737~cytoplasm,GO:0005813~centrosome,GO:0005814~centriole,GO:0005856~cytoskeleton,GO:0030054~cell junction,GO:0043296~apical junction complex,GO:0045095~keratin filament,GO:0097539~ciliary transition fiber, GO:0005515~protein binding, Alternative splicing,Cell junction,Cilium biogenesis/degradation,Coiled coil,Complete proteome,Cytoplasm,Cytoskeleton,Phosphoprotein,Reference proteome, chain:Fas-binding factor 1,modified residue,sequence conflict,splice variant, Q9Y6R7 Fc fragment of IgG binding protein(FCGBP) Homo sapiens GO:0070062~extracellular exosome, GO:0005515~protein binding, IPR000742:Epidermal growth factor-like domain,IPR001007:von Willebrand factor, type C,IPR001846:von Willebrand factor, type D domain,IPR002919:Trypsin Inhibitor-like, cysteine rich domain,IPR003645:Follistatin-like, N-terminal,IPR014853:Uncharacterised domain, cysteine-rich,IPR025615:TILa domain, SM00181:EGF,SM00214:VWC,SM00215:VWC_out,SM00216:VWD,SM00274:FOLN,SM00832:SM00832, Complete proteome,Disulfide bond,Glycoprotein,Polymorphism,Proteomics identification,Reference proteome,Repeat,Secreted,Signal, chain:IgGFc-binding protein,compositionally biased region:Cys-rich,disulfide bond,domain:TIL 1,domain:TIL 10,domain:TIL 11,domain:TIL 12,domain:TIL 2,domain:TIL 3,domain:TIL 4,domain:TIL 5,domain:TIL 6,domain:TIL 7,domain:TIL 8,domain:TIL 9,domain:VWFD 1,domain:VWFD 10,domain:VWFD 11,domain:VWFD 12,domain:VWFD 13,domain:VWFD 2,domain:VWFD 3,domain:VWFD 4,domain:VWFD 5,domain:VWFD 6,domain:VWFD 7,domain:VWFD 8,domain:VWFD 9,glycosylation site:N-linked (GlcNAc...),region of interest:IgGFc-binding,sequence conflict,sequence variant,signal peptide, P20693 Fc receptor, IgE, low affinity II, alpha polypeptide(Fcer2a) Mus musculus GO:0002925~positive regulation of humoral immune response mediated by circulating immunoglobulin,GO:0051000~positive regulation of nitric-oxide synthase activity,GO:0051712~positive regulation of killing of cells of other organism,GO:0051770~positive regulation of nitric-oxide synthase biosynthetic process, GO:0005886~plasma membrane,GO:0009897~external side of plasma membrane,GO:0016020~membrane,GO:0016021~integral component of membrane,GO:0070062~extracellular exosome, GO:0019863~IgE binding,GO:0030246~carbohydrate binding,GO:0046872~metal ion binding, IPR001304:C-type lectin,IPR016186:C-type lectin-like,IPR016187:C-type lectin fold,IPR018378:C-type lectin, conserved site, mmu04640:Hematopoietic cell lineage,mmu05169:Epstein-Barr virus infection, SM00034:CLECT, 3D-structure,Alternative splicing,Calcium,Cell membrane,Coiled coil,Complete proteome,Disulfide bond,Glycoprotein,IgE-binding protein,Lectin,Lipoprotein,Membrane,Metal-binding,Palmitate,Receptor,Reference proteome,Repeat,Signal,Signal-anchor,Transmembrane,Transmembrane helix, chain:Low affinity immunoglobulin epsilon Fc receptor,disulfide bond,domain:C-type lectin,glycosylation site:N-linked (GlcNAc...),helix,splice variant,strand,topological domain:Cytoplasmic,topological domain:Extracellular,transmembrane region, Q8IYU2 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1(HACE1) Homo sapiens GO:0006351~transcription, DNA-templated,GO:0006355~regulation of transcription, DNA-templated,GO:0007030~Golgi organization,GO:0007049~cell cycle,GO:0016567~protein ubiquitination,GO:0016601~Rac protein signal transduction,GO:0030334~regulation of cell migration,GO:0042787~protein ubiquitination involved in ubiquitin-dependent protein catabolic process,GO:0061025~membrane fusion,GO:0070936~protein K48-linked ubiquitination, GO:0000139~Golgi membrane,GO:0005634~nucleus,GO:0005783~endoplasmic reticulum,GO:0032580~Golgi cisterna membrane, GO:0004842~ubiquitin-protein transferase activity,GO:0005515~protein binding,GO:0016874~ligase activity,GO:0017137~Rab GTPase binding,GO:0048365~Rac GTPase binding, IPR000569:HECT,IPR002110:Ankyrin repeat,IPR020683:Ankyrin repeat-containing domain, SM00119:HECTc,SM00248:ANK, Alternative splicing,ANK repeat,Cell cycle,Chromosomal rearrangement,Complete proteome,Cytoplasm,Disease mutation,Endoplasmic reticulum,Golgi apparatus,Hereditary spastic paraplegia,Membrane,Neurodegeneration,Polymorphism,Proteomics identification,Reference proteome,Repeat,Transcription,Transcription regulation,Transferase,Ubl conjugation pathway, active site:Glycyl thioester intermediate,chain:E3 ubiquitin-protein ligase HACE1,domain:HECT,mutagenesis site,repeat:ANK 1,repeat:ANK 2,repeat:ANK 3,repeat:ANK 4,repeat:ANK 5,repeat:ANK 6,sequence variant,splice variant, Q7Z6Z7 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase(HUWE1) Homo sapiens GO:0000209~protein polyubiquitination,GO:0006284~base-excision repair,GO:0006513~protein monoubiquitination,GO:0016574~histone ubiquitination,GO:0030154~cell differentiation,GO:0042787~protein ubiquitination involved in ubiquitin-dependent protein catabolic process,GO:1903955~positive regulation of protein targeting to mitochondrion, GO:0005634~nucleus,GO:0005654~nucleoplasm,GO:0005737~cytoplasm,GO:0005829~cytosol,GO:0016020~membrane,GO:0016021~integral component of membrane,GO:0070062~extracellular exosome, GO:0003677~DNA binding,GO:0004842~ubiquitin-protein transferase activity,GO:0005515~protein binding,GO:0016874~ligase activity,GO:0044822~poly(A) RNA binding, IPR000569:HECT,IPR004170:WWE domain,IPR009060:UBA-like,IPR010309:E3 ubiquitin ligase, domain of unknown function DUF908,IPR010314:E3 ubiquitin ligase, domain of unknown function DUF913,IPR015940:Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote,IPR016024:Armadillo-type fold,IPR025527:Domain of unknown function DUF4414, hsa04120:Ubiquitin mediated proteolysis, 300706~Mental retardation, X-linked syndromic, Turner type, SM00119:HECTc,SM00165:UBA, 3D-structure,Acetylation,Alternative splicing,Chromosomal rearrangement,Coiled coil,Complete proteome,Cytoplasm,Differentiation,Disease mutation,DNA damage,DNA repair,DNA-binding,Membrane,Mental retardation,Methylation,Nucleus,Phosphoprotein,Polymorphism,Proteomics identification,Reference proteome,Transferase,Transmembrane,Transmembrane helix,Ubl conjugation pathway, active site:Glycyl thioester intermediate,chain:E3 ubiquitin-protein ligase HUWE1,compositionally biased region:Asp-rich,compositionally biased region:Glu-rich,compositionally biased region:Thr-rich,domain:HECT,domain:UBA,domain:WWE,helix,modified residue,mutagenesis site,repeat:UIM,sequence conflict,sequence variant,splice variant,strand,turn, Q7ZXZ0 MCM3 minichromosome maintenance deficient 3 (S. cerevisiae)(mcm3) Xenopus laevis GO:0006270~DNA replication initiation,GO:0007049~cell cycle,GO:0030174~regulation of DNA-dependent DNA replication initiation, GO:0005634~nucleus,GO:0042555~MCM complex, GO:0003677~DNA binding,GO:0003678~DNA helicase activity,GO:0005524~ATP binding, IPR001208:Mini-chromosome maintenance, DNA-dependent ATPase,IPR003593:AAA+ ATPase domain,IPR008046:DNA replication licensing factor Mcm3,IPR012340:Nucleic acid-binding, OB-fold,IPR018525:Mini-chromosome maintenance, conserved site,IPR027417:P-loop containing nucleoside triphosphate hydrolase, xla03030:DNA replication,xla04110:Cell cycle, SM00350:MCM,SM00382:AAA, ATP-binding,Cell cycle,DNA replication,DNA-binding,Helicase,Hydrolase,Nucleotide-binding,Nucleus, chain:Zygotic DNA replication licensing factor mcm3,domain:MCM,nucleotide phosphate-binding region:ATP, Q9Y5N5 N-6 adenine-specific DNA methyltransferase 1 (putative)(N6AMT1) Homo sapiens GO:0006415~translational termination,GO:0006479~protein methylation,GO:0030307~positive regulation of cell growth,GO:0032259~methylation, GO:0005829~cytosol,GO:0043234~protein complex, GO:0003676~nucleic acid binding,GO:0005515~protein binding,GO:0008276~protein methyltransferase activity, IPR002052:DNA methylase, N-6 adenine-specific, conserved site,IPR004557:Eukaryotic/archaeal PrmC-related,IPR007848:Methyltransferase small domain, Alternative splicing,Complete proteome,Methyltransferase,Polymorphism,Proteomics identification,Reference proteome,S-adenosyl-L-methionine,Transferase, chain:N(6)-adenine-specific DNA methyltransferase 1,sequence variant, Q96AB6 N-terminal asparagine amidase(NTAN1) Homo sapiens GO:0007613~memory,GO:0008344~adult locomotory behavior, GO:0005634~nucleus,GO:0005737~cytoplasm, GO:0008418~protein-N-terminal asparagine amidohydrolase activity, IPR026750:Protein N-terminal asparagine amidohydrolase, Complete proteome,Cytoplasm,Hydrolase,Polymorphism,Proteomics identification,Reference proteome, chain:Protein N-terminal asparagine amidohydrolase,sequence variant, Q5ZI67 NHL repeat containing 2(NHLRC2) Gallus gallus GO:0045454~cell redox homeostasis, GO:0005623~cell, IPR001258:NHL repeat,IPR011042:Six-bladed beta-propeller, TolB-like,IPR012336:Thioredoxin-like fold,IPR013017:NHL repeat, subgroup,IPR013766:Thioredoxin domain, Complete proteome,Reference proteome,Repeat, chain:NHL repeat-containing protein 2,domain:Thioredoxin,repeat:NHL 1,repeat:NHL 2,repeat:NHL 3,repeat:NHL 4,repeat:NHL 5,repeat:NHL 6, B5DF93 PAT1 homolog 1, processing body mRNA decay factor(Patl1) Rattus norvegicus GO:0000290~deadenylation-dependent decapping of nuclear-transcribed mRNA,GO:0033962~cytoplasmic mRNA processing body assembly, GO:0000932~cytoplasmic mRNA processing body,GO:0016605~PML body,GO:0016607~nuclear speck,GO:0030014~CCR4-NOT complex,GO:0043231~intracellular membrane-bounded organelle, GO:0003723~RNA binding,GO:0008266~poly(U) RNA binding,GO:0034046~poly(G) binding,GO:0044822~poly(A) RNA binding, IPR019167:Topoisomerase II-associated protein PAT1, rno03018:RNA degradation, Complete proteome,Cytoplasm,Methylation,Nucleus,Phosphoprotein,Reference proteome,RNA-binding, Q9U489 Protein lin-41(lin-41) Caenorhabditis elegans GO:0000003~reproduction,GO:0002119~nematode larval development,GO:0006898~receptor-mediated endocytosis,GO:0006915~apoptotic process,GO:0007275~multicellular organism development,GO:0007276~gamete generation,GO:0008406~gonad development,GO:0009957~epidermal cell fate specification,GO:0010171~body morphogenesis,GO:0018991~oviposition,GO:0018996~molting cycle, collagen and cuticulin-based cuticle,GO:0040011~locomotion,GO:0040018~positive regulation of multicellular organism growth,GO:0040027~negative regulation of vulval development,GO:0040034~regulation of development, heterochronic,GO:0042787~protein ubiquitination involved in ubiquitin-dependent protein catabolic process,GO:0044268~multicellular organismal protein metabolic process,GO:0045138~nematode male tail tip morphogenesis,GO:0045604~regulation of epidermal cell differentiation, GO:0005622~intracellular,GO:0005737~cytoplasm, GO:0004842~ubiquitin-protein transferase activity,GO:0008270~zinc ion binding,GO:0046872~metal ion binding, IPR000315:Zinc finger, B-box,IPR001258:NHL repeat,IPR001298:Filamin/ABP280 repeat,IPR003649:B-box, C-terminal,IPR011042:Six-bladed beta-propeller, TolB-like,IPR013017:NHL repeat, subgroup,IPR013783:Immunoglobulin-like fold,IPR014756:Immunoglobulin E-set,IPR017868:Filamin/ABP280 repeat-like, SM00336:BBOX,SM00502:BBC,SM00557:IG_FLMN, 3D-structure,Alternative splicing,Coiled coil,Complete proteome,Cytoplasm,Developmental protein,Metal-binding,Reference proteome,Repeat,Zinc,Zinc-finger, chain:Protein lin-41,compositionally biased region:Gln-rich,compositionally biased region:Poly-Pro,repeat:Filamin,repeat:NHL 1,repeat:NHL 2,repeat:NHL 3,repeat:NHL 4,repeat:NHL 5,repeat:NHL 6,splice variant,zinc finger region:B box-type; atypical,zinc finger region:RING-type, P35832 Protein tyrosine phosphatase 99A(Ptp99A) Drosophila melanogaster GO:0006470~protein dephosphorylation,GO:0007414~axonal defasciculation,GO:0007415~defasciculation of motor neuron axon,GO:0008045~motor neuron axon guidance,GO:0010906~regulation of glucose metabolic process, GO:0005886~plasma membrane,GO:0016021~integral component of membrane,GO:0030424~axon, GO:0004725~protein tyrosine phosphatase activity,GO:0005001~transmembrane receptor protein tyrosine phosphatase activity, IPR000242:Protein-tyrosine phosphatase, receptor/non-receptor type,IPR000387:Protein-tyrosine/Dual specificity phosphatase,IPR003595:Protein-tyrosine phosphatase, catalytic,IPR003961:Fibronectin, type III,IPR007110:Immunoglobulin-like domain,IPR013783:Immunoglobulin-like fold,IPR016130:Protein-tyrosine phosphatase, active site, SM00060:FN3,SM00194:PTPc,SM00404:PTPc_motif, Alternative splicing,Coiled coil,Complete proteome,Glycoprotein,Hydrolase,Membrane,Protein phosphatase,Reference proteome,Repeat,Signal,Transmembrane,Transmembrane helix, active site:Phosphocysteine intermediate,chain:Tyrosine-protein phosphatase 99A,compositionally biased region:Gln-rich,compositionally biased region:Poly-Ser,compositionally biased region:Ser-rich,domain:Fibronectin type-III 1,domain:Fibronectin type-III 2,domain:Fibronectin type-III 3,domain:Tyrosine-protein phosphatase 1,domain:Tyrosine-protein phosphatase 2,glycosylation site:N-linked (GlcNAc...),sequence conflict,signal peptide,splice variant,topological domain:Cytoplasmic,topological domain:Extracellular,transmembrane region, Q6DHC1 RAB18B, member RAS oncogene family(rab18b) Danio rerio GO:0001654~eye development,GO:0006810~transport,GO:0007264~small GTPase mediated signal transduction,GO:0007275~multicellular organism development,GO:0007420~brain development,GO:0015031~protein transport,GO:0034389~lipid particle organization,GO:0043009~chordate embryonic development, GO:0005622~intracellular, GO:0000166~nucleotide binding,GO:0005525~GTP binding, IPR001806:Small GTPase superfamily,IPR005225:Small GTP-binding protein domain,IPR025662:Sigma-54 interaction domain, ATP-binding site 1,IPR027417:P-loop containing nucleoside triphosphate hydrolase, Complete proteome,Developmental protein,GTP-binding,Lipoprotein,Methylation,Nucleotide-binding,Palmitate,Prenylation,Protein transport,Reference proteome,Transport, chain:Ras-related protein Rab-18-B,lipid moiety-binding region:S-geranylgeranyl cysteine,lipid moiety-binding region:S-palmitoyl cysteine,modified residue,nucleotide phosphate-binding region:GTP,propeptide:Removed in mature form,short sequence motif:Effector region, Q8CGC6 RNA binding motif protein 28(Rbm28) Mus musculus GO:0006397~mRNA processing,GO:0008380~RNA splicing, GO:0005634~nucleus,GO:0005681~spliceosomal complex,GO:0005730~nucleolus, GO:0000166~nucleotide binding,GO:0003676~nucleic acid binding,GO:0003723~RNA binding,GO:0044822~poly(A) RNA binding, IPR000504:RNA recognition motif domain,IPR012677:Nucleotide-binding, alpha-beta plait, mmu03008:Ribosome biogenesis in eukaryotes, SM00360:RRM, 3D-structure,Acetylation,Complete proteome,mRNA processing,mRNA splicing,Nucleus,Phosphoprotein,Proteomics identification,Reference proteome,Repeat,RNA-binding,Spliceosome, chain:RNA-binding protein 28,compositionally biased region:Asp/Glu-rich (acidic),domain:RRM 1,domain:RRM 2,domain:RRM 3,domain:RRM 4,helix,modified residue,sequence conflict,strand,turn, Q8VC34 RNA polymerase II associated protein 2(Rpap2) Mus musculus GO:0006351~transcription, DNA-templated,GO:0006355~regulation of transcription, DNA-templated,GO:0009301~snRNA transcription,GO:0070940~dephosphorylation of RNA polymerase II C-terminal domain, GO:0005634~nucleus,GO:0005730~nucleolus,GO:0005737~cytoplasm,GO:0016591~DNA-directed RNA polymerase II, holoenzyme, GO:0004721~phosphoprotein phosphatase activity,GO:0004722~protein serine/threonine phosphatase activity,GO:0008420~CTD phosphatase activity,GO:0016787~hydrolase activity,GO:0046872~metal ion binding, IPR007308:Protein of unknown function DUF408, Acetylation,Alternative splicing,Coiled coil,Complete proteome,Cytoplasm,Hydrolase,Metal-binding,Nucleus,Phosphoprotein,Protein phosphatase,Proteomics identification,Reference proteome,Transcription,Transcription regulation,Zinc,Zinc-finger, chain:RNA polymerase II-associated protein 2,sequence conflict,splice variant,transmembrane region, Q06455 RUNX1 translocation partner 1(RUNX1T1) Homo sapiens GO:0006091~generation of precursor metabolites and energy,GO:0006351~transcription, DNA-templated,GO:0045599~negative regulation of fat cell differentiation,GO:0045892~negative regulation of transcription, DNA-templated, GO:0005654~nucleoplasm,GO:0005737~cytoplasm,GO:0005739~mitochondrion,GO:0016363~nuclear matrix, GO:0003677~DNA binding,GO:0003700~transcription factor activity, sequence-specific DNA binding,GO:0003714~transcription corepressor activity,GO:0005515~protein binding,GO:0046872~metal ion binding, IPR002893:Zinc finger, MYND-type,IPR003894:TAFH/NHR1,IPR013289:Eight-Twenty-One,IPR013290:Myeloid transforming gene on chromosome 8 (MTG8),IPR014896:NHR2-like, hsa05200:Pathways in cancer,hsa05202:Transcriptional misregulation in cancer,hsa05221:Acute myeloid leukemia, SM00549:TAFH, 3D-structure,Alternative splicing,Chromosomal rearrangement,Coiled coil,Complete proteome,DNA-binding,Metal-binding,Nucleus,Phosphoprotein,Polymorphism,Proteomics identification,Proto-oncogene,Reference proteome,Repressor,Transcription,Transcription regulation,Zinc,Zinc-finger, chain:Protein CBFA2T1,compositionally biased region:Poly-Pro,compositionally biased region:Poly-Ser,domain:TAFH,helix,modified residue,mutagenesis site,region of interest:Important for oligomerization,sequence conflict,sequence variant,site:Breakpoint for translocation to form AML1-MTG8 in AML-M2,splice variant,strand,zinc finger region:MYND-type, Q9BY12 S-phase cyclin A associated protein in the ER(SCAPER) Homo sapiens GO:0005634~nucleus,GO:0005737~cytoplasm,GO:0005783~endoplasmic reticulum, GO:0003676~nucleic acid binding,GO:0008270~zinc ion binding, IPR003604:Zinc finger, U1-type, SM00451:ZnF_U1, Alternative splicing,Coiled coil,Complete proteome,Endoplasmic reticulum,Metal-binding,Nucleus,Phosphoprotein,Polymorphism,Proteomics identification,Reference proteome,Zinc,Zinc-finger, chain:S phase cyclin A-associated protein in the endoplasmic reticulum,compositionally biased region:Glu-rich,modified residue,mutagenesis site,sequence conflict,sequence variant,splice variant,zinc finger region:C2H2-type, Q5QNA6 SCAR-like protein 2(LOC9268854) Oryza sativa Japonica Group GO:0030036~actin cytoskeleton organization, GO:0005737~cytoplasm,GO:0005856~cytoskeleton, IPR003124:WH2 domain, Actin-binding,Complete proteome,Cytoplasm,Cytoskeleton,Reference proteome, P53992 SEC24 homolog C, COPII coat complex component(SEC24C) Homo sapiens Intracellular trafficking and secretion, GO:0002474~antigen processing and presentation of peptide antigen via MHC class I,GO:0006886~intracellular protein transport,GO:0006888~ER to Golgi vesicle-mediated transport,GO:0019886~antigen processing and presentation of exogenous peptide antigen via MHC class II,GO:0048208~COPII vesicle coating, GO:0000139~Golgi membrane,GO:0005789~endoplasmic reticulum membrane,GO:0005829~cytosol,GO:0012507~ER to Golgi transport vesicle membrane,GO:0030127~COPII vesicle coat,GO:0048471~perinuclear region of cytoplasm, GO:0005515~protein binding,GO:0008270~zinc ion binding, IPR002035:von Willebrand factor, type A,IPR006895:Zinc finger, Sec23/Sec24-type,IPR006896:Sec23/Sec24, trunk domain,IPR006900:Sec23/Sec24, helical domain,IPR007123:Gelsolin domain,IPR012990:Sec23/Sec24 beta-sandwich, hsa04141:Protein processing in endoplasmic reticulum, 3D-structure,Alternative splicing,Complete proteome,Cytoplasm,Endoplasmic reticulum,ER-Golgi transport,Golgi apparatus,Membrane,Phosphoprotein,Polymorphism,Protein transport,Proteomics identification,Reference proteome,Transport, chain:Protein transport protein Sec24C,helix,modified residue,region of interest:Zinc finger-like,sequence variant,strand,turn, Q5F3X8 SEC31 homolog A (S. cerevisiae)(SEC31A) Gallus gallus GO:0015031~protein transport,GO:0016192~vesicle-mediated transport,GO:0051592~response to calcium ion, GO:0005789~endoplasmic reticulum membrane,GO:0012507~ER to Golgi transport vesicle membrane,GO:0030120~vesicle coat,GO:0030134~ER to Golgi transport vesicle,GO:0048471~perinuclear region of cytoplasm,GO:0070971~endoplasmic reticulum exit site, IPR001680:WD40 repeat,IPR015943:WD40/YVTN repeat-like-containing domain,IPR017986:WD40-repeat-containing domain, gga04141:Protein processing in endoplasmic reticulum, SM00320:WD40, Coiled coil,Complete proteome,Cytoplasm,Cytoplasmic vesicle,Endoplasmic reticulum,ER-Golgi transport,Membrane,Protein transport,Reference proteome,Repeat,Transport,WD repeat, chain:Protein transport protein Sec31A,compositionally biased region:Pro-rich,repeat:WD 1,repeat:WD 2,repeat:WD 3,repeat:WD 4,repeat:WD 5,repeat:WD 6,repeat:WD 7, Q6P5D8 SMC hinge domain containing 1(Smchd1) Mus musculus GO:0009048~dosage compensation by inactivation of X chromosome,GO:0051276~chromosome organization,GO:0060821~inactivation of X chromosome by DNA methylation, GO:0000784~nuclear chromosome, telomeric region,GO:0001740~Barr body,GO:0005694~chromosome, GO:0005524~ATP binding, IPR003594:Histidine kinase-like ATPase, ATP-binding domain,IPR010935:SMCs flexible hinge, SM00968:SM00968, Acetylation,Chromosome,Complete proteome,Isopeptide bond,Phosphoprotein,Reference proteome,Ubl conjugation, chain:Structural maintenance of chromosomes flexible hinge domain-containing protein 1,modified residue,sequence conflict, A0JPH4 SREBF chaperone S homeolog(scap.S) Xenopus laevis GO:0008203~cholesterol metabolic process,GO:0032933~SREBP signaling pathway, GO:0000139~Golgi membrane,GO:0005789~endoplasmic reticulum membrane,GO:0012507~ER to Golgi transport vesicle membrane,GO:0016021~integral component of membrane, GO:0015485~cholesterol binding, IPR000731:Sterol-sensing domain,IPR001680:WD40 repeat,IPR015943:WD40/YVTN repeat-like-containing domain,IPR017986:WD40-repeat-containing domain,IPR019775:WD40 repeat, conserved site, SM00320:WD40, Cholesterol metabolism,Cytoplasmic vesicle,Endoplasmic reticulum,Glycoprotein,Golgi apparatus,Lipid metabolism,Membrane,Repeat,Steroid metabolism,Sterol metabolism,Transmembrane,Transmembrane helix,WD repeat, chain:Sterol regulatory element-binding protein cleavage-activating protein,domain:SSD,glycosylation site:N-linked (GlcNAc...),region of interest:ER export signal,region of interest:Interaction with srebf,repeat:WD 1,repeat:WD 2,repeat:WD 3,repeat:WD 4,repeat:WD 5,repeat:WD 6,repeat:WD 7,topological domain:Cytoplasmic,topological domain:Lumenal,transmembrane region, Q5FVJ8 SUMO/sentrin peptidase family member, NEDD8 specific(Senp8) Rattus norvegicus GO:0006508~proteolysis, GO:0008234~cysteine-type peptidase activity, IPR003653:Peptidase C48, SUMO/Sentrin/Ubl1, Acetylation,Complete proteome,Hydrolase,Protease,Reference proteome,Thiol protease,Ubl conjugation pathway, active site:Nucleophile,chain:Sentrin-specific protease 8,modified residue,region of interest:Protease, Q9H270 VPS11, CORVET/HOPS core subunit(VPS11) Homo sapiens GO:0006886~intracellular protein transport,GO:0006904~vesicle docking involved in exocytosis,GO:0006914~autophagy,GO:0007032~endosome organization,GO:0007040~lysosome organization,GO:0008333~endosome to lysosome transport,GO:0016192~vesicle-mediated transport,GO:0031647~regulation of protein stability,GO:0034058~endosomal vesicle fusion,GO:0035542~regulation of SNARE complex assembly,GO:1901998~toxin transport,GO:1902115~regulation of organelle assembly,GO:1903364~positive regulation of cellular protein catabolic process,GO:1903955~positive regulation of protein targeting to mitochondrion,GO:2000643~positive regulation of early endosome to late endosome transport, GO:0005622~intracellular,GO:0005764~lysosome,GO:0005765~lysosomal membrane,GO:0005768~endosome,GO:0005769~early endosome,GO:0005770~late endosome,GO:0005776~autophagosome,GO:0005884~actin filament,GO:0030123~AP-3 adaptor complex,GO:0030136~clathrin-coated vesicle,GO:0030139~endocytic vesicle,GO:0030897~HOPS complex,GO:0031902~late endosome membrane,GO:0033263~CORVET complex, GO:0000166~nucleotide binding,GO:0005515~protein binding,GO:0008270~zinc ion binding,GO:0019904~protein domain specific binding,GO:0019905~syntaxin binding,GO:0030674~protein binding, bridging, IPR000547:Clathrin, heavy chain/VPS, 7-fold repeat,IPR001841:Zinc finger, RING-type,IPR011990:Tetratricopeptide-like helical,IPR013083:Zinc finger, RING/FYVE/PHD-type,IPR015943:WD40/YVTN repeat-like-containing domain,IPR016024:Armadillo-type fold,IPR016528:Vacuolar protein sorting-associated protein 11,IPR017986:WD40-repeat-containing domain,IPR024763:Vacuolar protein sorting protein 11, C-terminal, SM00184:RING, Acetylation,Autophagy,Coiled coil,Complete proteome,Cytoplasmic vesicle,Disease mutation,Endosome,Leukodystrophy,Lysosome,Membrane,Metal-binding,Methylation,Nucleotide-binding,Phosphoprotein,Polymorphism,Protein transport,Proteomics identification,Reference proteome,Repeat,Transport,Zinc,Zinc-finger, chain:Vacuolar protein sorting-associated protein 11 homolog,modified residue,repeat:Clathrin,sequence conflict,sequence variant,zinc finger region:RING-type, Q8C190 VPS9 domain containing 1(Vps9d1) Mus musculus IPR003123:Vacuolar sorting protein 9,IPR007330:MIT, SM00167:VPS9, Alternative splicing,Complete proteome,Phosphoprotein,Proteomics identification,Reference proteome, chain:Uncharacterized protein C16orf7 homolog,domain:VPS9,splice variant, Q6PAX7 WD repeat domain 1 S homeolog(wdr1.S) Xenopus laevis GO:0030043~actin filament fragmentation, GO:0005634~nucleus,GO:0005737~cytoplasm,GO:0005884~actin filament,GO:0005886~plasma membrane, GO:0003779~actin binding,GO:0051015~actin filament binding, IPR001680:WD40 repeat,IPR011045:Nitrous oxide reductase, N-terminal,IPR015943:WD40/YVTN repeat-like-containing domain,IPR017986:WD40-repeat-containing domain,IPR019775:WD40 repeat, conserved site,IPR020472:G-protein beta WD-40 repeat,IPR024977:Anaphase-promoting complex subunit 4, WD40 domain, SM00320:WD40, Actin-binding,Cell membrane,Cytoplasm,Cytoskeleton,Membrane,Nucleus,Repeat,WD repeat, chain:WD repeat-containing protein 1-B,repeat:WD 1,repeat:WD 10,repeat:WD 11,repeat:WD 2,repeat:WD 3,repeat:WD 4,repeat:WD 5,repeat:WD 6,repeat:WD 7,repeat:WD 8,repeat:WD 9, Q9D994 WD repeat domain 38(Wdr38) Mus musculus GO:0002244~hematopoietic progenitor cell differentiation, IPR001680:WD40 repeat,IPR015943:WD40/YVTN repeat-like-containing domain,IPR017986:WD40-repeat-containing domain,IPR019775:WD40 repeat, conserved site,IPR020472:G-protein beta WD-40 repeat, SM00320:WD40, Complete proteome,Reference proteome,Repeat,WD repeat, chain:WD repeat-containing protein 38,repeat:WD 1,repeat:WD 2,repeat:WD 3,repeat:WD 4,repeat:WD 5,repeat:WD 6,repeat:WD 7, Q61824 a disintegrin and metallopeptidase domain 12 (meltrin alpha)(Adam12) Mus musculus m_cardiacEGFPathway:Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, GO:0006508~proteolysis,GO:0007155~cell adhesion,GO:0007173~epidermal growth factor receptor signaling pathway, GO:0005654~nucleoplasm,GO:0005739~mitochondrion,GO:0005886~plasma membrane,GO:0016020~membrane,GO:0016021~integral component of membrane, GO:0004222~metalloendopeptidase activity,GO:0008233~peptidase activity,GO:0008237~metallopeptidase activity,GO:0016787~hydrolase activity,GO:0017124~SH3 domain binding,GO:0046872~metal ion binding, IPR000742:Epidermal growth factor-like domain,IPR001590:Peptidase M12B, ADAM/reprolysin,IPR001762:Blood coagulation inhibitor, Disintegrin,IPR002870:Peptidase M12B, propeptide,IPR006586:ADAM, cysteine-rich,IPR018358:Disintegrin, conserved site,IPR024079:Metallopeptidase, catalytic domain, SM00050:DISIN,SM00608:ACR, Cell adhesion,Cleavage on pair of basic residues,Complete proteome,Disulfide bond,EGF-like domain,Glycoprotein,Hydrolase,Membrane,Metal-binding,Metalloprotease,Phosphoprotein,Protease,Reference proteome,SH3-binding,Signal,Transmembrane,Transmembrane helix,Zinc,Zymogen, chain:Disintegrin and metalloproteinase domain- containing protein 12,compositionally biased region:Cys-rich,disulfide bond,domain:Disintegrin,domain:EGF-like,domain:Peptidase M12B,glycosylation site:N-linked (GlcNAc...),metal ion-binding site:Zinc; catalytic,metal ion-binding site:Zinc; in inhibited form,modified residue,short sequence motif:Cysteine switch,short sequence motif:SH3-binding; class I,short sequence motif:SH3-binding; class II,signal peptide,topological domain:Cytoplasmic,topological domain:Extracellular,transmembrane region, Q3B7N2 actinin alpha 1(ACTN1) Bos taurus GO:0030220~platelet formation,GO:0043462~regulation of ATPase activity,GO:0045214~sarcomere organization,GO:0046928~regulation of neurotransmitter secretion,GO:0048041~focal adhesion assembly,GO:0048741~skeletal muscle fiber development,GO:0051017~actin filament bundle assembly,GO:0051234~establishment of localization,GO:0051271~negative regulation of cellular component movement,GO:0051639~actin filament network formation,GO:0051764~actin crosslink formation,GO:1903506~regulation of nucleic acid-templated transcription, GO:0001725~stress fiber,GO:0001726~ruffle,GO:0005615~extracellular space,GO:0005884~actin filament,GO:0005903~brush border,GO:0005915~zonula adherens,GO:0005916~fascia adherens,GO:0005923~bicellular tight junction,GO:0005925~focal adhesion,GO:0012506~vesicle membrane,GO:0016328~lateral plasma membrane,GO:0030018~Z disc,GO:0030027~lamellipodium,GO:0030486~smooth muscle dense body,GO:0031252~cell leading edge,GO:0042383~sarcolemma,GO:0070062~extracellular exosome,GO:0090636~outer dense plaque of desmosome,GO:0090637~inner dense plaque of desmosome,GO:0097433~dense body,GO:1990357~terminal web, GO:0003725~double-stranded RNA binding,GO:0005178~integrin binding,GO:0005509~calcium ion binding,GO:0005523~tropomyosin binding,GO:0017166~vinculin binding,GO:0030374~ligand-dependent nuclear receptor transcription coactivator activity,GO:0042803~protein homodimerization activity,GO:0043495~protein anchor,GO:0044325~ion channel binding,GO:0051015~actin filament binding,GO:0051393~alpha-actinin binding, IPR001589:Actinin-type, actin-binding, conserved site,IPR001715:Calponin homology domain,IPR002017:Spectrin repeat,IPR002048:EF-hand domain,IPR011992:EF-hand-like domain,IPR014837:EF-hand, Ca insensitive,IPR018159:Spectrin/alpha-actinin,IPR018247:EF-Hand 1, calcium-binding site,IPR026921:Alpha-actinin, bta04510:Focal adhesion,bta04520:Adherens junction,bta04530:Tight junction,bta04670:Leukocyte transendothelial migration,bta04810:Regulation of actin cytoskeleton,bta05146:Amoebiasis,bta05203:Viral carcinogenesis,bta05322:Systemic lupus erythematosus, SM00033:CH,SM00054:EFh,SM00150:SPEC, Acetylation,Actin-binding,Calcium,Cell junction,Cell membrane,Cell projection,Coiled coil,Complete proteome,Cytoplasm,Cytoskeleton,Membrane,Metal-binding,Phosphoprotein,Reference proteome,Repeat, chain:Alpha-actinin-1,domain:Actin-binding,domain:CH 1,domain:CH 2,domain:EF-hand 1,domain:EF-hand 2,modified residue,region of interest:Interaction with DDN,repeat:Spectrin 1,repeat:Spectrin 2,repeat:Spectrin 3,repeat:Spectrin 4, P12814 actinin alpha 1(ACTN1) Homo sapiens h_cell2cellPathway:Cell to Cell Adhesion Signaling,h_integrinPathway:Integrin Signaling Pathway,h_uCalpainPathway:uCalpain and friends in Cell spread, GO:0002576~platelet degranulation,GO:0007015~actin filament organization,GO:0030168~platelet activation,GO:0030220~platelet formation,GO:0036344~platelet morphogenesis,GO:0042981~regulation of apoptotic process,GO:0048041~focal adhesion assembly,GO:0051017~actin filament bundle assembly,GO:0051271~negative regulation of cellular component movement,GO:0051639~actin filament network formation,GO:0051764~actin crosslink formation,GO:0070527~platelet aggregation,GO:1903506~regulation of nucleic acid-templated transcription, GO:0001725~stress fiber,GO:0001726~ruffle,GO:0005576~extracellular region,GO:0005615~extracellular space,GO:0005622~intracellular,GO:0005737~cytoplasm,GO:0005829~cytosol,GO:0005884~actin filament,GO:0005886~plasma membrane,GO:0005903~brush border,GO:0005911~cell-cell junction,GO:0005916~fascia adherens,GO:0005925~focal adhesion,GO:0030018~Z disc,GO:0031093~platelet alpha granule lumen,GO:0031143~pseudopodium,GO:0042995~cell projection,GO:0070062~extracellular exosome, GO:0003725~double-stranded RNA binding,GO:0005178~integrin binding,GO:0005509~calcium ion binding,GO:0005515~protein binding,GO:0017166~vinculin binding,GO:0030374~ligand-dependent nuclear receptor transcription coactivator activity,GO:0042803~protein homodimerization activity,GO:0044325~ion channel binding,GO:0051015~actin filament binding, IPR001589:Actinin-type, actin-binding, conserved site,IPR001715:Calponin homology domain,IPR002017:Spectrin repeat,IPR002048:EF-hand domain,IPR011992:EF-hand-like domain,IPR014837:EF-hand, Ca insensitive,IPR018159:Spectrin/alpha-actinin,IPR018247:EF-Hand 1, calcium-binding site,IPR026921:Alpha-actinin, hsa04510:Focal adhesion,hsa04520:Adherens junction,hsa04530:Tight junction,hsa04670:Leukocyte transendothelial migration,hsa04810:Regulation of actin cytoskeleton,hsa05146:Amoebiasis,hsa05203:Viral carcinogenesis,hsa05322:Systemic lupus erythematosus, 615193~Bleeding disorder, platelet-type, 15, SM00033:CH,SM00054:EFh,SM00150:SPEC, 3D-structure,Acetylation,Actin-binding,Alternative splicing,Calcium,Cell junction,Cell membrane,Cell projection,Coiled coil,Complete proteome,Cytoplasm,Cytoskeleton,Direct protein sequencing,Disease mutation,Membrane,Metal-binding,Phosphoprotein,Polymorphism,Proteomics identification,Reference proteome,Repeat, chain:Alpha-actinin-1,domain:Actin-binding,domain:CH 1,domain:CH 2,domain:EF-hand 1,domain:EF-hand 2,helix,modified residue,region of interest:Interaction with DDN,repeat:Spectrin 1,repeat:Spectrin 2,repeat:Spectrin 3,repeat:Spectrin 4,sequence conflict,sequence variant,strand,turn, P79098 alanyl aminopeptidase, membrane(ANPEP) Bos taurus Amino acid transport and metabolism, GO:0001525~angiogenesis,GO:0006508~proteolysis,GO:0030154~cell differentiation,GO:0043171~peptide catabolic process,GO:0046718~viral entry into host cell, GO:0005615~extracellular space,GO:0005737~cytoplasm,GO:0005765~lysosomal membrane,GO:0005793~endoplasmic reticulum-Golgi intermediate compartment,GO:0005886~plasma membrane,GO:0009897~external side of plasma membrane,GO:0016021~integral component of membrane,GO:0070062~extracellular exosome, GO:0001618~virus receptor activity,GO:0008237~metallopeptidase activity,GO:0008270~zinc ion binding,GO:0042277~peptide binding,GO:0070006~metalloaminopeptidase activity, IPR001930:Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase,IPR014782:Peptidase M1, membrane alanine aminopeptidase, N-terminal,IPR024571:Domain of unknown function DUF3358, bta00480:Glutathione metabolism,bta01100:Metabolic pathways,bta04614:Renin-angiotensin system,bta04640:Hematopoietic cell lineage, Aminopeptidase,Angiogenesis,Complete proteome,Developmental protein,Differentiation,Disulfide bond,Glycoprotein,Host cell receptor for virus entry,Hydrolase,Membrane,Metal-binding,Metalloprotease,Protease,Receptor,Reference proteome,Signal-anchor,Sulfation,Transmembrane,Transmembrane helix,Zinc, active site:Proton donor,chain:Aminopeptidase N,glycosylation site:N-linked (GlcNAc...),metal ion-binding site:Zinc; catalytic,modified residue,region of interest:Cytosolic Ser/Thr-rich junction,region of interest:Metalloprotease,topological domain:Cytoplasmic,transmembrane region, Q5RE52 anaphase promoting complex subunit 5(ANAPC5) Pongo abelii GO:0007067~mitotic nuclear division,GO:0051301~cell division,GO:0070979~protein K11-linked ubiquitination, GO:0005680~anaphase-promoting complex, IPR011990:Tetratricopeptide-like helical,IPR019734:Tetratricopeptide repeat,IPR026000:Anaphase-promoting complex subunit 5,TPR-containing domain, pon04110:Cell cycle,pon04114:Oocyte meiosis,pon04120:Ubiquitin mediated proteolysis,pon04914:Progesterone-mediated oocyte maturation,pon05166:HTLV-I infection, SM00028:TPR, Cell cycle,Cell division,Complete proteome,Mitosis,Phosphoprotein,Reference proteome,Repeat,TPR repeat,Ubl conjugation pathway, chain:Anaphase-promoting complex subunit 5,modified residue,repeat:TPR 1,repeat:TPR 2,repeat:TPR 3,repeat:TPR 4, O15084 ankyrin repeat domain 28(ANKRD28) Homo sapiens General function prediction only, GO:0048208~COPII vesicle coating, GO:0000139~Golgi membrane,GO:0005654~nucleoplasm,GO:0005829~cytosol, GO:0005515~protein binding, IPR002110:Ankyrin repeat,IPR020683:Ankyrin repeat-containing domain, SM00248:ANK, Alternative promoter usage,Alternative splicing,ANK repeat,Complete proteome,Nucleus,Phosphoprotein,Proteomics identification,Reference proteome,Repeat, chain:Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A,modified residue,mutagenesis site,repeat:ANK 1,repeat:ANK 10,repeat:ANK 11,repeat:ANK 12,repeat:ANK 13,repeat:ANK 14,repeat:ANK 15,repeat:ANK 16,repeat:ANK 17,repeat:ANK 18,repeat:ANK 19,repeat:ANK 2,repeat:ANK 20,repeat:ANK 21,repeat:ANK 22,repeat:ANK 23,repeat:ANK 24,repeat:ANK 25,repeat:ANK 26,repeat:ANK 27,repeat:ANK 3,repeat:ANK 4,repeat:ANK 5,repeat:ANK 6,repeat:ANK 7,repeat:ANK 8,repeat:ANK 9,sequence conflict,splice variant, Q8BHY3 anoctamin 1, calcium activated chloride channel(Ano1) Mus musculus GO:0006810~transport,GO:0006811~ion transport,GO:0006812~cation transport,GO:0006821~chloride transport,GO:0007200~phospholipase C-activating G-protein coupled receptor signaling pathway,GO:0007275~multicellular organism development,GO:0015705~iodide transport,GO:0034605~cellular response to heat,GO:0035774~positive regulation of insulin secretion involved in cellular response to glucose stimulus,GO:0042391~regulation of membrane potential,GO:0050965~detection of temperature stimulus involved in sensory perception of pain,GO:0050966~detection of mechanical stimulus involved in sensory perception of pain,GO:0060438~trachea development,GO:1902476~chloride transmembrane transport, GO:0005737~cytoplasm,GO:0005886~plasma membrane,GO:0009897~external side of plasma membrane,GO:0016020~membrane,GO:0016021~integral component of membrane,GO:0016324~apical plasma membrane,GO:0034707~chloride channel complex,GO:0070062~extracellular exosome, GO:0005227~calcium activated cation channel activity,GO:0005229~intracellular calcium activated chloride channel activity,GO:0005247~voltage-gated chloride channel activity,GO:0005254~chloride channel activity,GO:0015111~iodide transmembrane transporter activity,GO:0017128~phospholipid scramblase activity,GO:0042803~protein homodimerization activity,GO:0046982~protein heterodimerization activity,GO:0046983~protein dimerization activity, IPR007632:Anoctamin/TMEM 16, Alternative splicing,Calcium,Cell membrane,Chloride,Chloride channel,Complete proteome,Cytoplasm,Developmental protein,Glycoprotein,Ion channel,Ion transport,Membrane,Phosphoprotein,Proteomics identification,Reference proteome,Transmembrane,Transmembrane helix,Transport, chain:Anoctamin-1,glycosylation site:N-linked (GlcNAc...),mutagenesis site,splice variant,topological domain:Cytoplasmic,topological domain:Extracellular,transmembrane region, P07293 calcium voltage-gated channel subunit alpha1 S(CACNA1S) Oryctolagus cuniculus GO:0006936~muscle contraction, GO:0005891~voltage-gated calcium channel complex,GO:0030315~T-tubule,GO:0031674~I band, GO:0005245~voltage-gated calcium channel activity,GO:0008331~high voltage-gated calcium channel activity,GO:0046872~metal ion binding, IPR002077:Voltage-dependent calcium channel, alpha-1 subunit,IPR005446:Voltage-dependent calcium channel, L-type, alpha-1 subunit,IPR005450:Voltage-dependent calcium channel, L-type, alpha-1S subunit,IPR005821:Ion transport domain,IPR014873:Voltage-dependent calcium channel, alpha-1 subunit, IQ domain,IPR027359:Voltage-dependent potassium channel, four helix bundle domain, ocu04010:MAPK signaling pathway,ocu04020:Calcium signaling pathway,ocu04022:cGMP-PKG signaling pathway,ocu04024:cAMP signaling pathway,ocu04260:Cardiac muscle contraction,ocu04261:Adrenergic signaling in cardiomyocytes,ocu04270:Vascular smooth muscle contraction,ocu04723:Retrograde endocannabinoid signaling,ocu04725:Cholinergic synapse,ocu04726:Serotonergic synapse,ocu04727:GABAergic synapse,ocu04911:Insulin secretion,ocu04912:GnRH signaling pathway,ocu04921:Oxytocin signaling pathway,ocu04924:Renin secretion,ocu04925:Aldosterone synthesis and secretion,ocu05010:Alzheimer's disease,ocu05410:Hypertrophic cardiomyopathy (HCM),ocu05412:Arrhythmogenic right ventricular cardiomyopathy (ARVC),ocu05414:Dilated cardiomyopathy, SM01062:SM01062, 3D-structure,Calcium,Calcium channel,Calcium transport,Complete proteome,Direct protein sequencing,Disulfide bond,Glycoprotein,Ion channel,Ion transport,Membrane,Metal-binding,Phosphoprotein,Polymorphism,Reference proteome,Repeat,Transmembrane,Transmembrane helix,Transport,Voltage-gated channel, chain:Voltage-dependent L-type calcium channel subunit alpha-1S,compositionally biased region:Poly-Leu,glycosylation site:N-linked (GlcNAc...),helix,modified residue,region of interest:Binding to the beta subunit,region of interest:Dihydropyridine binding,region of interest:Phenylalkylamine binding,repeat:I,repeat:II,repeat:III,repeat:IV,sequence conflict,sequence variant,site:Calcium ion selectivity and permeability,site:Cleavage,topological domain:Cytoplasmic,topological domain:Extracellular,transmembrane region,turn, Q8BUG5 calcyphosphine 2(Caps2) Mus musculus GO:0005509~calcium ion binding,GO:0046872~metal ion binding, IPR002048:EF-hand domain,IPR011992:EF-hand-like domain,IPR018247:EF-Hand 1, calcium-binding site, Alternative splicing,Calcium,Complete proteome,Metal-binding,Reference proteome,Repeat, calcium-binding region:1,calcium-binding region:2,chain:Calcyphosin-2,domain:EF-hand 1,domain:EF-hand 2,domain:EF-hand 3,sequence conflict,splice variant, Q5T5Y3 calmodulin regulated spectrin associated protein 1(CAMSAP1) Homo sapiens GO:0007010~cytoskeleton organization,GO:0022604~regulation of cell morphogenesis,GO:0031175~neuron projection development, GO:0005737~cytoplasm,GO:0005874~microtubule, GO:0005516~calmodulin binding,GO:0008017~microtubule binding,GO:0030507~spectrin binding, IPR001715:Calponin homology domain,IPR011033:PRC-barrel-like,IPR014797:CKK domain,IPR022613:Calmodulin-regulated spectrin-associated protein, CH domain, SM01051:SM01051, Alternative splicing,Coiled coil,Complete proteome,Cytoplasm,Cytoskeleton,Microtubule,Phosphoprotein,Polymorphism,Reference proteome, chain:Calmodulin-regulated spectrin-associated protein 1,compositionally biased region:Poly-Glu,compositionally biased region:Poly-Ser,domain:CKK,modified residue,sequence conflict,sequence variant,splice variant, Q3U2J5 calmodulin-lysine N-methyltransferase(Camkmt) Mus musculus GO:0007005~mitochondrion organization,GO:0018022~peptidyl-lysine methylation,GO:0032259~methylation, GO:0005634~nucleus,GO:0005737~cytoplasm,GO:0005794~Golgi apparatus, GO:0008168~methyltransferase activity,GO:0016740~transferase activity,GO:0018025~calmodulin-lysine N-methyltransferase activity, IPR019410:Nicotinamide N-methyltransferase-like,IPR025800:Calmodulin-lysine N-methyltransferase, mmu00310:Lysine degradation, Alternative splicing,Complete proteome,Cytoplasm,Golgi apparatus,Methyltransferase,Nucleus,Reference proteome,S-adenosyl-L-methionine,Transferase, chain:Uncharacterized protein C2orf34 homolog,splice variant, Q80UY1 carnosine N-methyltransferase 1(Carnmt1) Mus musculus GO:0032259~methylation,GO:0035498~carnosine metabolic process, GO:0005634~nucleus,GO:0005737~cytoplasm,GO:0005829~cytosol, GO:0008168~methyltransferase activity,GO:0016740~transferase activity,GO:0030735~carnosine N-methyltransferase activity, IPR012901:N2227-like, SM01296:SM01296, Complete proteome,Cytoplasm,Methyltransferase,Nucleus,Reference proteome,S-adenosyl-L-methionine,Transferase, chain:UPF0586 protein C9orf41 homolog,sequence conflict, U3JAG9 centrosomal protein 131(cep131) Danio rerio GO:0006810~transport,GO:0010824~regulation of centrosome duplication,GO:0030030~cell projection organization,GO:0030154~cell differentiation,GO:0032402~melanosome transport,GO:0035721~intraciliary retrograde transport,GO:0035735~intraciliary transport involved in cilium morphogenesis,GO:0050953~sensory perception of light stimulus,GO:0060271~cilium morphogenesis,GO:0060287~epithelial cilium movement involved in determination of left/right asymmetry,GO:0070121~Kupffer's vesicle development,GO:0090317~negative regulation of intracellular protein transport, GO:0000775~chromosome, centromeric region,GO:0005694~chromosome,GO:0005929~cilium,GO:0034451~centriolar satellite, Centromere,Chromosome,Cilium biogenesis/degradation,Coiled coil,Complete proteome,Differentiation,Proteomics identification,Reference proteome,Transport, Q28FA8 centrosomal protein 41kDa(cep41) Xenopus tropicalis GO:0015031~protein transport,GO:0016337~single organismal cell-cell adhesion,GO:0018095~protein polyglutamylation,GO:0042384~cilium assembly, GO:0005814~centriole,GO:0005886~plasma membrane,GO:0005911~cell-cell junction,GO:0009986~cell surface,GO:0036064~ciliary basal body,GO:0072372~primary cilium, IPR001763:Rhodanese-like domain, SM00450:RHOD, Cell projection,Ciliopathy,Cilium,Cilium biogenesis/degradation,Complete proteome,Cytoplasm,Cytoskeleton,Protein transport,Reference proteome,Transport, Q5JTW2 centrosomal protein 78(CEP78) Homo sapiens GO:0000086~G2/M transition of mitotic cell cycle, GO:0005813~centrosome,GO:0005829~cytosol, IPR001611:Leucine-rich repeat,IPR026212:Centrosomal protein of 78kDa, Alternative splicing,Coiled coil,Complete proteome,Cytoplasm,Cytoskeleton,Phosphoprotein,Proteomics identification,Reference proteome, chain:Centrosomal protein of 78 kDa,modified residue,repeat:LRR 1,repeat:LRR 2,repeat:LRR 3,sequence conflict,splice variant, O70496 chloride channel, voltage-sensitive 7(Clcn7) Mus musculus GO:0006810~transport,GO:0006811~ion transport,GO:0006821~chloride transport,GO:0009268~response to pH,GO:0055085~transmembrane transport,GO:1902476~chloride transmembrane transport, GO:0005764~lysosome,GO:0005765~lysosomal membrane,GO:0016020~membrane,GO:0016021~integral component of membrane,GO:0031410~cytoplasmic vesicle, GO:0000166~nucleotide binding,GO:0005216~ion channel activity,GO:0005247~voltage-gated chloride channel activity,GO:0005524~ATP binding,GO:0015297~antiporter activity,GO:0031404~chloride ion binding, IPR000644:Cystathionine beta-synthase, core,IPR001807:Chloride channel, voltage gated,IPR002249:Chloride channel ClC-7,IPR014743:Chloride channel, core, SM00116:CBS, Antiport,ATP-binding,CBS domain,Chloride,Complete proteome,Ion transport,Lysosome,Membrane,Nucleotide-binding,Phosphoprotein,Proteomics identification,Reference proteome,Repeat,Transmembrane,Transmembrane helix,Transport, binding site:Chloride,binding site:Chloride; via amide nitrogen,chain:H(+)/Cl(-) exchange transporter 7,domain:CBS 1,domain:CBS 2,modified residue,nucleotide phosphate-binding region:ATP,region of interest:In-membrane helix,region of interest:In-membrane loop between two helices,short sequence motif:Selectivity filter part_1,short sequence motif:Selectivity filter part_2,short sequence motif:Selectivity filter part_3,site:Mediates proton transfer from the outer aqueous phase to the interior of the protein; involved in linking H(+) and Cl(-) transport,site:Mediates proton transfer from the protein to the inner aqueous phase,topological domain:Cytoplasmic,transmembrane region, Q96N23 cilia and flagella associated protein 54(CFAP54) Homo sapiens GO:0007283~spermatogenesis,GO:0030154~cell differentiation,GO:0042384~cilium assembly,GO:0060271~cilium morphogenesis,GO:0060294~cilium movement involved in cell motility, GO:0005737~cytoplasm,GO:0005930~axoneme,GO:0016021~integral component of membrane, IPR011990:Tetratricopeptide-like helical, Alternative splicing,Cell projection,Cilium,Cilium biogenesis/degradation,Complete proteome,Cytoplasm,Cytoskeleton,Differentiation,Membrane,Polymorphism,Proteomics identification,Reference proteome,Spermatogenesis,Transmembrane,Transmembrane helix, chain:Uncharacterized protein C12orf55,sequence variant, P53621 coatomer protein complex subunit alpha(COPA) Homo sapiens h_arapPathway:ADP-Ribosylation Factor, GO:0006886~intracellular protein transport,GO:0006888~ER to Golgi vesicle-mediated transport,GO:0006890~retrograde vesicle-mediated transport, Golgi to ER,GO:0006891~intra-Golgi vesicle-mediated transport,GO:0030157~pancreatic juice secretion, GO:0000139~Golgi membrane,GO:0005615~extracellular space,GO:0005737~cytoplasm,GO:0005789~endoplasmic reticulum membrane,GO:0005829~cytosol,GO:0016020~membrane,GO:0030126~COPI vesicle coat,GO:0030133~transport vesicle,GO:0070062~extracellular exosome, GO:0005179~hormone activity,GO:0005198~structural molecule activity, IPR001680:WD40 repeat,IPR006692:Coatomer, WD associated region,IPR010714:Coatomer, alpha subunit, C-terminal,IPR011048:Cytochrome cd1-nitrite reductase-like, C-terminal haem d1,IPR015943:WD40/YVTN repeat-like-containing domain,IPR016391:Coatomer alpha subunit,IPR017986:WD40-repeat-containing domain,IPR019775:WD40 repeat, conserved site,IPR020472:G-protein beta WD-40 repeat,IPR024977:Anaphase-promoting complex subunit 4, WD40 domain, 616414~Autoimmune interstitial lung, joint, and kidney disease, PIRSF003354:coatomer, alpha subunit, SM00320:WD40, Alternative splicing,Complete proteome,Cytoplasm,Cytoplasmic vesicle,Direct protein sequencing,Disease mutation,ER-Golgi transport,Golgi apparatus,Hormone,Membrane,Methylation,Phosphoprotein,Polymorphism,Protein transport,Reference proteome,Repeat,RNA editing,Secreted,Transport,WD repeat, chain:Coatomer subunit alpha,modified residue,peptide:Proxenin,peptide:Xenin,repeat:WD 1,repeat:WD 2,repeat:WD 3,repeat:WD 4,repeat:WD 5,repeat:WD 6,sequence conflict,sequence variant,splice variant, Q07DZ5 cortactin binding protein 2(CTTNBP2) Ornithorhynchus anatinus GO:0005938~cell cortex,GO:0016021~integral component of membrane,GO:0043197~dendritic spine, IPR002110:Ankyrin repeat,IPR019131:Cortactin-binding protein-2, N-terminal,IPR020683:Ankyrin repeat-containing domain, SM00248:ANK, ANK repeat,Cell projection,Coiled coil,Complete proteome,Cytoplasm,Membrane,Methylation,Phosphoprotein,Reference proteome,Repeat,Transmembrane,Transmembrane helix, Q6GPF3 cullin 3 S homeolog(cul3.S) Xenopus laevis GO:0006513~protein monoubiquitination,GO:0006888~ER to Golgi vesicle-mediated transport,GO:0007080~mitotic metaphase plate congression,GO:0007229~integrin-mediated signaling pathway,GO:0016477~cell migration,GO:0016567~protein ubiquitination,GO:0017145~stem cell division,GO:0035024~negative regulation of Rho protein signal transduction,GO:0040016~embryonic cleavage,GO:0043149~stress fiber assembly,GO:0043161~proteasome-mediated ubiquitin-dependent protein catabolic process,GO:0045842~positive regulation of mitotic metaphase/anaphase transition,GO:0048208~COPII vesicle coating, GO:0000139~Golgi membrane,GO:0005634~nucleus,GO:0005827~polar microtubule,GO:0031463~Cul3-RING ubiquitin ligase complex, IPR001373:Cullin, N-terminal,IPR011991:Winged helix-turn-helix DNA-binding domain,IPR016157:Cullin, conserved site,IPR016158:Cullin homology,IPR016159:Cullin repeat-like-containing domain,IPR019559:Cullin protein, neddylation domain, xla04120:Ubiquitin mediated proteolysis, SM00182:CULLIN,SM00884:SM00884, ER-Golgi transport,Isopeptide bond,Nucleus,Transport,Ubl conjugation, chain:Cullin-3-B,cross-link:Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in NEDD8), Q91WT9 cystathionine beta-synthase(Cbs) Mus musculus m_methioninePathway:Catabolic Pathways for Methionine, Isoleucine, Threonine and Valine, GO:0001958~endochondral ossification,GO:0001974~blood vessel remodeling,GO:0006535~cysteine biosynthetic process from serine,GO:0006563~L-serine metabolic process,GO:0006801~superoxide metabolic process,GO:0008652~cellular amino acid biosynthetic process,GO:0019343~cysteine biosynthetic process via cystathionine,GO:0019344~cysteine biosynthetic process,GO:0019346~transsulfuration,GO:0021587~cerebellum morphogenesis,GO:0030823~regulation of cGMP metabolic process,GO:0043066~negative regulation of apoptotic process,GO:0043418~homocysteine catabolic process,GO:0043506~regulation of JUN kinase activity,GO:0050667~homocysteine metabolic process,GO:0050880~regulation of blood vessel size,GO:0051593~response to folic acid,GO:0060135~maternal process involved in female pregnancy,GO:0060351~cartilage development involved in endochondral bone morphogenesis,GO:0070814~hydrogen sulfide biosynthetic process,GO:0071456~cellular response to hypoxia, GO:0005634~nucleus,GO:0005737~cytoplasm,GO:0005829~cytosol, GO:0004122~cystathionine beta-synthase activity,GO:0004124~cysteine synthase activity,GO:0016829~lyase activity,GO:0019825~oxygen binding,GO:0019899~enzyme binding,GO:0020037~heme binding,GO:0030170~pyridoxal phosphate binding,GO:0031625~ubiquitin protein ligase binding,GO:0042802~identical protein binding,GO:0042803~protein homodimerization activity,GO:0046872~metal ion binding,GO:0050421~nitrite reductase (NO-forming) activity,GO:0070025~carbon monoxide binding,GO:0070026~nitric oxide binding,GO:0072341~modified amino acid binding,GO:1904047~S-adenosyl-L-methionine binding, IPR000644:Cystathionine beta-synthase, core,IPR001216:Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site,IPR001926:Tryptophan synthase beta subunit-like PLP-dependent enzymes superfamily,IPR005857:Cystathionine beta-synthase, mmu00260:Glycine, serine and threonine metabolism,mmu00270:Cysteine and methionine metabolism,mmu01100:Metabolic pathways,mmu01130:Biosynthesis of antibiotics,mmu01230:Biosynthesis of amino acids, SM00116:CBS, Alternative splicing,Amino-acid biosynthesis,CBS domain,Complete proteome,Cysteine biosynthesis,Cytoplasm,Heme,Iron,Isopeptide bond,Lyase,Metal-binding,Nucleus,Phosphoprotein,Proteomics identification,Pyridoxal phosphate,Reference proteome,Ubl conjugation, binding site:Pyridoxal phosphate,chain:Cystathionine beta-synthase,cross-link:Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO),domain:CBS,metal ion-binding site:Iron (heme axial ligand),modified residue,region of interest:Pyridoxal phosphate binding,splice variant, P32929 cystathionine gamma-lyase(CTH) Homo sapiens h_methioninePathway:Catabolic Pathways for Methionine, Isoleucine, Threonine and Valine, GO:0000098~sulfur amino acid catabolic process,GO:0006534~cysteine metabolic process,GO:0018272~protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine,GO:0019343~cysteine biosynthetic process via cystathionine,GO:0019344~cysteine biosynthetic process,GO:0019346~transsulfuration,GO:0030968~endoplasmic reticulum unfolded protein response,GO:0043123~positive regulation of I-kappaB kinase/NF-kappaB signaling,GO:0044524~protein sulfhydration,GO:0051092~positive regulation of NF-kappaB transcription factor activity,GO:0051289~protein homotetramerization,GO:0070814~hydrogen sulfide biosynthetic process,GO:0071266~'de novo' L-methionine biosynthetic process,GO:1904831~positive regulation of aortic smooth muscle cell differentiation,GO:2001234~negative regulation of apoptotic signaling pathway, GO:0005634~nucleus,GO:0005737~cytoplasm,GO:0005829~cytosol,GO:0070062~extracellular exosome, GO:0003962~cystathionine gamma-synthase activity,GO:0004123~cystathionine gamma-lyase activity,GO:0005515~protein binding,GO:0005516~calmodulin binding,GO:0016846~carbon-sulfur lyase activity,GO:0030170~pyridoxal phosphate binding,GO:0042802~identical protein binding,GO:0044540~L-cystine L-cysteine-lyase (deaminating),GO:0047982~homocysteine desulfhydrase activity,GO:0080146~L-cysteine desulfhydrase activity, IPR000277:Cys/Met metabolism, pyridoxal phosphate-dependent enzyme,IPR015421:Pyridoxal phosphate-dependent transferase, major region, subdomain 1,IPR015422:Pyridoxal phosphate-dependent transferase, major region, subdomain 2,IPR015424:Pyridoxal phosphate-dependent transferase, hsa00260:Glycine, serine and threonine metabolism,hsa00270:Cysteine and methionine metabolism,hsa00450:Selenocompound metabolism,hsa01100:Metabolic pathways,hsa01130:Biosynthesis of antibiotics,hsa01230:Biosynthesis of amino acids, 219500~Cystathioninuria,Homocysteine, total plasma, elevated~Homocysteine, total plasma, elevated, PIRSF001434:cystathionine gamma-synthase, 3D-structure,Alternative splicing,Amino-acid biosynthesis,Calmodulin-binding,Complete proteome,Cysteine biosynthesis,Cytoplasm,Disease mutation,Lyase,Polymorphism,Pyridoxal phosphate,Reference proteome, binding site:Substrate,chain:Cystathionine gamma-lyase,helix,modified residue,sequence variant,splice variant,strand,turn, Q7T3Q2 cysteine rich transmembrane BMP regulator 1 (chordin-like)(crim1) Danio rerio GO:0001558~regulation of cell growth,GO:0001568~blood vessel development,GO:0001756~somitogenesis,GO:0048570~notochord morphogenesis, GO:0005576~extracellular region,GO:0016020~membrane,GO:0016021~integral component of membrane, GO:0004857~enzyme inhibitor activity,GO:0004867~serine-type endopeptidase inhibitor activity,GO:0005520~insulin-like growth factor binding, IPR000867:Insulin-like growth factor-binding protein, IGFBP,IPR001007:von Willebrand factor, type C,IPR004094:Proteinase inhibitor I15, antistasin-like,IPR009030:Insulin-like growth factor binding protein, N-terminal,IPR011061:Proteinase inhibitor I14/I15, hirudin/antistatin, SM00121:IB,SM00214:VWC,SM00215:VWC_out, Complete proteome,Glycoprotein,Membrane,Reference proteome,Repeat,Signal,Transmembrane,Transmembrane helix, chain:Cysteine-rich motor neuron 1 protein,domain:Antistasin-like 1,domain:Antistasin-like 2,domain:Antistasin-like 3,domain:Antistasin-like 4,domain:IGFBP N-terminal,domain:VWFC 1,domain:VWFC 2,domain:VWFC 3,domain:VWFC 4,domain:VWFC 5,domain:VWFC 6,glycosylation site:N-linked (GlcNAc...),short sequence motif:Cell attachment site,signal peptide,topological domain:Cytoplasmic,topological domain:Extracellular,transmembrane region, P78329 cytochrome P450 family 4 subfamily F member 2(CYP4F2) Homo sapiens Secondary metabolites biosynthesis, transport, and catabolism, GO:0000038~very long-chain fatty acid metabolic process,GO:0001676~long-chain fatty acid metabolic process,GO:0003091~renal water homeostasis,GO:0003095~pressure natriuresis,GO:0006690~icosanoid metabolic process,GO:0006691~leukotriene metabolic process,GO:0007596~blood coagulation,GO:0008217~regulation of blood pressure,GO:0017144~drug metabolic process,GO:0019369~arachidonic acid metabolic process,GO:0019373~epoxygenase P450 pathway,GO:0032304~negative regulation of icosanoid secretion,GO:0032305~positive regulation of icosanoid secretion,GO:0036101~leukotriene B4 catabolic process,GO:0042360~vitamin E metabolic process,GO:0042361~menaquinone catabolic process,GO:0042376~phylloquinone catabolic process,GO:0042377~vitamin K catabolic process,GO:0055078~sodium ion homeostasis,GO:0055114~oxidation-reduction process,GO:0097267~omega-hydroxylase P450 pathway, GO:0005737~cytoplasm,GO:0005789~endoplasmic reticulum membrane,GO:0016021~integral component of membrane,GO:0016324~apical plasma membrane,GO:0031090~organelle membrane,GO:0043231~intracellular membrane-bounded organelle, GO:0004497~monooxygenase activity,GO:0005506~iron ion binding,GO:0005515~protein binding,GO:0008392~arachidonic acid epoxygenase activity,GO:0016705~oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen,GO:0016709~oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen,GO:0018685~alkane 1-monooxygenase activity,GO:0020037~heme binding,GO:0050051~leukotriene-B4 20-monooxygenase activity,GO:0052869~arachidonic acid omega-hydroxylase activity,GO:0052871~alpha-tocopherol omega-hydroxylase activity,GO:0052872~tocotrienol omega-hydroxylase activity,GO:0097258~20-hydroxy-leukotriene B4 omega oxidase activity,GO:0097259~20-aldehyde-leukotriene B4 20-monooxygenase activity, IPR001128:Cytochrome P450,IPR002401:Cytochrome P450, E-class, group I,IPR017972:Cytochrome P450, conserved site, hsa00590:Arachidonic acid metabolism,hsa01100:Metabolic pathways, Alternative splicing,Complete proteome,Direct protein sequencing,Endoplasmic reticulum,Heme,Iron,Membrane,Metal-binding,Microsome,Monooxygenase,NADP,Oxidoreductase,Polymorphism,Proteomics identification,Reference proteome,Signal,Transmembrane,Transmembrane helix, binding site:Heme (covalent; via 1 link),chain:Leukotriene-B(4) omega-hydroxylase 1,metal ion-binding site:Iron (heme axial ligand),sequence conflict,sequence variant, Q15438 cytohesin 1(CYTH1) Homo sapiens h_arapPathway:ADP-Ribosylation Factor, GO:0016192~vesicle-mediated transport,GO:0030155~regulation of cell adhesion,GO:0032012~regulation of ARF protein signal transduction,GO:0043547~positive regulation of GTPase activity, GO:0000139~Golgi membrane,GO:0005737~cytoplasm,GO:0005829~cytosol,GO:0005886~plasma membrane,GO:0031234~extrinsic component of cytoplasmic side of plasma membrane, GO:0005086~ARF guanyl-nucleotide exchange factor activity,GO:0005515~protein binding,GO:0008289~lipid binding, IPR000904:SEC7-like,IPR001849:Pleckstrin homology domain,IPR011993:Pleckstrin homology-like domain,IPR023394:SEC7-like, alpha orthogonal bundle, hsa04144:Endocytosis, SM00222:Sec7,SM00233:PH, 3D-structure,Acetylation,Alternative splicing,Cell membrane,Coiled coil,Complete proteome,Cytoplasm,Guanine-nucleotide releasing factor,Lipid-binding,Membrane,Proteomics identification,Reference proteome, chain:Cytohesin-1,domain:PH,domain:SEC7,helix,sequence conflict,splice variant,strand,turn, O60879 diaphanous related formin 2(DIAPH2) Homo sapiens GO:0000910~cytokinesis,GO:0007015~actin filament organization,GO:0007275~multicellular organism development,GO:0007292~female gamete generation,GO:0048477~oogenesis, GO:0005730~nucleolus,GO:0005739~mitochondrion,GO:0005769~early endosome,GO:0005794~Golgi apparatus,GO:0005829~cytosol,GO:0043231~intracellular membrane-bounded organelle, GO:0003779~actin binding,GO:0005102~receptor binding,GO:0017048~Rho GTPase binding, IPR010465:DRF autoregulatory,IPR010472:Diaphanous FH3,IPR010473:Diaphanous GTPase-binding,IPR014767:Diaphanous autoregulatory,IPR014768:GTPase-binding/formin homology 3,IPR015425:Actin-binding FH2,IPR016024:Armadillo-type fold, hsa04810:Regulation of actin cytoskeleton, 300511~Premature ovarian failure, SM00498:FH2,SM01139:SM01139,SM01140:SM01140, Acetylation,Alternative splicing,Coiled coil,Complete proteome,Cytoplasm,Developmental protein,Differentiation,Endosome,Oogenesis,Polymorphism,Premature ovarian failure,Proteomics identification,Reference proteome,Repeat, chain:Protein diaphanous homolog 2,compositionally biased region:Arg/Lys-rich (basic),compositionally biased region:Poly-Leu,compositionally biased region:Poly-Lys,compositionally biased region:Poly-Pro,compositionally biased region:Poly-Ser,domain:DAD,domain:FH1,domain:FH2,domain:GBD/FH3,modified residue,sequence variant,splice variant, P09623 dihydrolipoamide dehydrogenase(DLD) Sus scrofa GO:0006120~mitochondrial electron transport, NADH to ubiquinone,GO:0006508~proteolysis,GO:0007369~gastrulation,GO:0042391~regulation of membrane potential,GO:0045454~cell redox homeostasis,GO:0048240~sperm capacitation,GO:0055114~oxidation-reduction process, GO:0005654~nucleoplasm,GO:0005739~mitochondrion,GO:0005759~mitochondrial matrix,GO:0005929~cilium,GO:0043159~acrosomal matrix,GO:0043209~myelin sheath,GO:0045254~pyruvate dehydrogenase complex, GO:0004148~dihydrolipoyl dehydrogenase activity,GO:0016668~oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor,GO:0034604~pyruvate dehydrogenase (NAD+) activity,GO:0050660~flavin adenine dinucleotide binding, IPR004099:Pyridine nucleotide-disulphide oxidoreductase, dimerisation,IPR006258:Dihydrolipoamide dehydrogenase,IPR012999:Pyridine nucleotide-disulphide oxidoreductase, class I, active site,IPR016156:FAD/NAD-linked reductase, dimerisation,IPR023753:Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain, ssc00010:Glycolysis / Gluconeogenesis,ssc00020:Citrate cycle (TCA cycle),ssc00260:Glycine, serine and threonine metabolism,ssc00280:Valine, leucine and isoleucine degradation,ssc00620:Pyruvate metabolism,ssc00630:Glyoxylate and dicarboxylate metabolism,ssc01100:Metabolic pathways,ssc01130:Biosynthesis of antibiotics,ssc01200:Carbon metabolism, Acetylation,Complete proteome,Direct protein sequencing,Disulfide bond,FAD,Flavoprotein,Mitochondrion,NAD,Oxidoreductase,Phosphoprotein,Proteomics identification,Redox-active center,Reference proteome,Transit peptide, active site:Proton acceptor,binding site:FAD,binding site:FAD; via amide nitrogen and carbonyl oxygen,binding site:NAD,binding site:NAD; via amide nitrogen,binding site:NAD; via amide nitrogen and carbonyl oxygen,chain:Dihydrolipoyl dehydrogenase, mitochondrial,disulfide bond,modified residue,nucleotide phosphate-binding region:FAD,nucleotide phosphate-binding region:NAD,sequence conflict,transit peptide:Mitochondrion, P15330 dorsal(dl) Drosophila melanogaster GO:0000122~negative regulation of transcription from RNA polymerase II promoter,GO:0000381~regulation of alternative mRNA splicing, via spliceosome,GO:0001715~ectodermal cell fate specification,GO:0006355~regulation of transcription, DNA-templated,GO:0006357~regulation of transcription from RNA polymerase II promoter,GO:0006952~defense response,GO:0006955~immune response,GO:0006964~positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria,GO:0007249~I-kappaB kinase/NF-kappaB signaling,GO:0007369~gastrulation,GO:0007398~ectoderm development,GO:0007419~ventral cord development,GO:0007498~mesoderm development,GO:0007501~mesodermal cell fate specification,GO:0007507~heart development,GO:0008063~Toll signaling pathway,GO:0008354~germ cell migration,GO:0009950~dorsal/ventral axis specification,GO:0009952~anterior/posterior pattern specification,GO:0009953~dorsal/ventral pattern formation,GO:0010004~gastrulation involving germ band extension,GO:0010629~negative regulation of gene expression,GO:0010906~regulation of glucose metabolic process,GO:0034097~response to cytokine,GO:0035006~melanization defense response,GO:0035206~regulation of hemocyte proliferation,GO:0038061~NIK/NF-kappaB signaling,GO:0042387~plasmatocyte differentiation,GO:0045892~negative regulation of transcription, DNA-templated,GO:0045893~positive regulation of transcription, DNA-templated,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,GO:0048935~peripheral nervous system neuron development, GO:0005634~nucleus,GO:0005737~cytoplasm,GO:0005829~cytosol,GO:0031594~neuromuscular junction,GO:0033256~I-kappaB/NF-kappaB complex,GO:0071212~subsynaptic reticulum, GO:0000977~RNA polymerase II regulatory region sequence-specific DNA binding,GO:0001077~transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding,GO:0003677~DNA binding,GO:0003682~chromatin binding,GO:0003700~transcription factor activity, sequence-specific DNA binding,GO:0003705~transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding,GO:0005515~protein binding,GO:0043565~sequence-specific DNA binding,GO:0070379~high mobility group box 1 binding,GO:0070491~repressing transcription factor binding, IPR000451:NF-kappa-B/Rel/Dorsal,IPR002909:Cell surface receptor IPT/TIG,IPR008967:p53-like transcription factor, DNA-binding,IPR011363:Dorsal protein,IPR011539:Rel homology domain,IPR013783:Immunoglobulin-like fold,IPR014756:Immunoglobulin E-set, PIRSF001716:dorsal protein, SM00429:IPT, Activator,Alternative splicing,Complete proteome,Cytoplasm,Developmental protein,DNA-binding,Nucleus,Phosphoprotein,Proteomics identification,Reference proteome,Transcription,Transcription regulation, chain:Embryonic polarity protein dorsal,compositionally biased region:Gln-rich,compositionally biased region:Pro-rich,domain:RHD,modified residue,sequence conflict,short sequence motif:Nuclear localization signal,splice variant, B9EJR8 dynein, axonemal assembly factor 5(Dnaaf5) Mus musculus GO:0003341~cilium movement,GO:0030030~cell projection organization,GO:0036158~outer dynein arm assembly,GO:0036159~inner dynein arm assembly, GO:0005737~cytoplasm,GO:0031514~motile cilium, GO:0045505~dynein intermediate chain binding, IPR011989:Armadillo-like helical,IPR016024:Armadillo-type fold, Acetylation,Cilium biogenesis/degradation,Complete proteome,Cytoplasm,Proteomics identification,Reference proteome,Repeat, Q16206 ecto-NOX disulfide-thiol exchanger 2(ENOX2) Homo sapiens GO:0007624~ultradian rhythm,GO:0016049~cell growth,GO:0040008~regulation of growth,GO:0055114~oxidation-reduction process, GO:0005615~extracellular space,GO:0005829~cytosol,GO:0009897~external side of plasma membrane, GO:0000166~nucleotide binding,GO:0003676~nucleic acid binding,GO:0015035~protein disulfide oxidoreductase activity, IPR000504:RNA recognition motif domain,IPR012677:Nucleotide-binding, alpha-beta plait, SM00360:RRM, Alternative splicing,Biological rhythms,Cell membrane,Coiled coil,Complete proteome,Copper,Direct protein sequencing,Electron transport,Glycoprotein,Growth regulation,Membrane,NAD,Oxidoreductase,Polymorphism,Proteomics identification,Reference proteome,Secreted,Transport, chain:Ecto-NOX disulfide-thiol exchanger 2,compositionally biased region:Pro-rich,domain:RRM,mutagenesis site,sequence conflict,splice variant, Q9EST3 eukaryotic translation initiation factor 4E nuclear import factor 1(Eif4enif1) Mus musculus GO:0006810~transport,GO:0015031~protein transport,GO:0017148~negative regulation of translation,GO:0019827~stem cell population maintenance,GO:0045665~negative regulation of neuron differentiation, GO:0000932~cytoplasmic mRNA processing body,GO:0005634~nucleus,GO:0005737~cytoplasm,GO:0005829~cytosol,GO:0016020~membrane,GO:0016605~PML body,GO:0016607~nuclear speck,GO:0043231~intracellular membrane-bounded organelle, GO:0003729~mRNA binding,GO:0005515~protein binding,GO:0044822~poly(A) RNA binding, IPR018862:Eukaryotic translation initiation factor 4E transporter, Acetylation,Alternative splicing,Complete proteome,Cytoplasm,Nucleus,Phosphoprotein,Protein transport,Proteomics identification,Reference proteome,Transport, chain:Eukaryotic translation initiation factor 4E transporter,compositionally biased region:Arg-rich,modified residue,region of interest:EIF4E-binding,sequence conflict,short sequence motif:Nuclear export signal,short sequence motif:Nuclear localization signal,splice variant, Q5ZLT0 exportin 7(XPO7) Gallus gallus Nuclear structure / Intracellular trafficking and secretion, GO:0006611~protein export from nucleus, GO:0005643~nuclear pore,GO:0005737~cytoplasm, GO:0005049~nuclear export signal receptor activity,GO:0008536~Ran GTPase binding, IPR001494:Importin-beta, N-terminal,IPR016024:Armadillo-type fold, SM00913:SM00913, Complete proteome,Cytoplasm,Nucleus,Protein transport,Reference proteome,Transport, chain:Exportin-7,domain:Importin N-terminal, Q66KE9 family with sequence similarity 161 member A L homeolog(fam161a.L) Xenopus laevis GO:0030030~cell projection organization, GO:0005737~cytoplasm,GO:0005856~cytoskeleton,GO:0005929~cilium, IPR019579:Uncharacterised protein family UPF0564, Cell projection,Cilium,Cilium biogenesis/degradation,Coiled coil,Cytoplasm,Cytoskeleton, chain:Protein FAM161A, Q5ZML6 family with sequence similarity 210 member A(FAM210A) Gallus gallus GO:0005739~mitochondrion,GO:0016021~integral component of membrane, IPR009688:Domain of unknown function DUF1279, Coiled coil,Complete proteome,Membrane,Mitochondrion,Reference proteome,Transmembrane,Transmembrane helix, chain:Uncharacterized protein C18orf19 homolog,domain:DUF1279,transmembrane region, Q5ZKN5 family with sequence similarity 53 member A(FAM53A) Gallus gallus GO:0006606~protein import into nucleus, GO:0005634~nucleus, Complete proteome,Nucleus,Reference proteome, chain:Protein FAM53A,sequence conflict,short sequence motif:Nuclear localization signal, Q5F3L9 family with sequence similarity 65, member B(FAM65B) Gallus gallus GO:0007605~sensory perception of sound,GO:0048741~skeletal muscle fiber development, GO:0005737~cytoplasm,GO:0060171~stereocilium membrane, IPR011989:Armadillo-like helical,IPR016024:Armadillo-type fold,IPR026136:Protein FAM65, Cell membrane,Cell projection,Coiled coil,Complete proteome,Cytoplasm,Hearing,Membrane,Reference proteome, chain:Protein FAM65B,region of interest:Interacts with NCAM, Q80U16 family with sequence similarity 65, member B(Fam65b) Mus musculus GO:0007605~sensory perception of sound,GO:0048741~skeletal muscle fiber development, GO:0005737~cytoplasm,GO:0005886~plasma membrane,GO:0016020~membrane,GO:0016324~apical plasma membrane,GO:0042995~cell projection,GO:0060171~stereocilium membrane, GO:0005515~protein binding, IPR011989:Armadillo-like helical,IPR016024:Armadillo-type fold,IPR026136:Protein FAM65, Alternative splicing,Cell membrane,Cell projection,Coiled coil,Complete proteome,Cytoplasm,Hearing,Membrane,Phosphoprotein,Proteomics identification,Reference proteome, chain:Protein FAM65B,modified residue,sequence conflict,splice variant, Q9JJN1 fibroblast growth factor 21(Fgf21) Mus musculus GO:0008284~positive regulation of cell proliferation,GO:0008543~fibroblast growth factor receptor signaling pathway,GO:0010898~positive regulation of triglyceride catabolic process,GO:0014823~response to activity,GO:0030968~endoplasmic reticulum unfolded protein response,GO:0031667~response to nutrient levels,GO:0035690~cellular response to drug,GO:0046326~positive regulation of glucose import,GO:0070374~positive regulation of ERK1 and ERK2 cascade,GO:0071333~cellular response to glucose stimulus,GO:0071377~cellular response to glucagon stimulus,GO:0071404~cellular response to low-density lipoprotein particle stimulus,GO:0072577~endothelial cell apoptotic process,GO:0090080~positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway,GO:1901215~negative regulation of neuron death,GO:1904640~response to methionine,GO:2000352~negative regulation of endothelial cell apoptotic process, GO:0005576~extracellular region,GO:0005615~extracellular space,GO:0005623~cell, GO:0005102~receptor binding,GO:0005104~fibroblast growth factor receptor binding,GO:0008083~growth factor activity, IPR002209:Heparin-binding growth factor/Fibroblast growth factor,IPR008996:Cytokine, IL-1-like, mmu04010:MAPK signaling pathway,mmu04014:Ras signaling pathway,mmu04015:Rap1 signaling pathway,mmu04151:PI3K-Akt signaling pathway,mmu04810:Regulation of actin cytoskeleton,mmu05200:Pathways in cancer,mmu05218:Melanoma, SM00442:FGF, Complete proteome,Growth factor,Reference proteome,Secreted,Signal, chain:Fibroblast growth factor 21,signal peptide, Q6ZPF4 formin-like 3(Fmnl3) Mus musculus GO:0001525~angiogenesis,GO:0007010~cytoskeleton organization,GO:0007275~multicellular organism development,GO:0008360~regulation of cell shape,GO:0016043~cellular component organization,GO:0016477~cell migration,GO:0030036~actin cytoskeleton organization, GO:0005737~cytoplasm,GO:0005886~plasma membrane,GO:0016020~membrane, GO:0003779~actin binding,GO:0005515~protein binding,GO:0017048~Rho GTPase binding,GO:0032794~GTPase activating protein binding, IPR010472:Diaphanous FH3,IPR010473:Diaphanous GTPase-binding,IPR014768:GTPase-binding/formin homology 3,IPR015425:Actin-binding FH2,IPR016024:Armadillo-type fold, SM00498:FH2,SM01139:SM01139,SM01140:SM01140, 3D-structure,Alternative splicing,Angiogenesis,Cell membrane,Coiled coil,Complete proteome,Cytoplasm,Developmental protein,Lipoprotein,Membrane,Myristate,Phosphoprotein,Proteomics identification,Reference proteome, chain:Formin-like protein 3,compositionally biased region:Pro-rich,domain:FH2,domain:GBD/FH3,modified residue,splice variant, Q9P2T1 guanosine monophosphate reductase 2(GMPR2) Homo sapiens GO:0006144~purine nucleobase metabolic process,GO:0006163~purine nucleotide metabolic process,GO:0015951~purine ribonucleotide interconversion,GO:0043101~purine-containing compound salvage,GO:0046037~GMP metabolic process,GO:0055114~oxidation-reduction process, GO:0005737~cytoplasm,GO:0005829~cytosol,GO:1902560~GMP reductase complex, GO:0003824~catalytic activity,GO:0003920~GMP reductase activity,GO:0016491~oxidoreductase activity,GO:0046872~metal ion binding, IPR001093:IMP dehydrogenase/GMP reductase,IPR005993:Guanosine monophosphate reductase 1,IPR013785:Aldolase-type TIM barrel,IPR015875:IMP dehydrogenase / GMP reductase, conserved site, hsa00230:Purine metabolism, PIRSF000235:GMP reductase, 3D-structure,Acetylation,Alternative splicing,Complete proteome,Metal-binding,NADP,Oxidoreductase,Polymorphism,Potassium,Proteomics identification,Purine metabolism,Reference proteome, active site:Thioimidate intermediate,binding site:NADP,chain:GMP reductase 2,helix,metal ion-binding site:Potassium; via carbonyl oxygen,modified residue,nucleotide phosphate-binding region:NADP,sequence conflict,sequence variant,strand,turn, P14625 heat shock protein 90 beta family member 1(HSP90B1) Homo sapiens GO:0001666~response to hypoxia,GO:0002224~toll-like receptor signaling pathway,GO:0006457~protein folding,GO:0006898~receptor-mediated endocytosis,GO:0006950~response to stress,GO:0015031~protein transport,GO:0030433~ER-associated ubiquitin-dependent protein catabolic process,GO:0030970~retrograde protein transport, ER to cytosol,GO:0031247~actin rod assembly,GO:0034975~protein folding in endoplasmic reticulum,GO:0034976~response to endoplasmic reticulum stress,GO:0036500~ATF6-mediated unfolded protein response,GO:0043066~negative regulation of apoptotic process,GO:0043666~regulation of phosphoprotein phosphatase activity,GO:0051208~sequestering of calcium ion,GO:0071318~cellular response to ATP, GO:0005576~extracellular region,GO:0005634~nucleus,GO:0005783~endoplasmic reticulum,GO:0005788~endoplasmic reticulum lumen,GO:0005789~endoplasmic reticulum membrane,GO:0005829~cytosol,GO:0005886~plasma membrane,GO:0005925~focal adhesion,GO:0016020~membrane,GO:0030496~midbody,GO:0031012~extracellular matrix,GO:0034663~endoplasmic reticulum chaperone complex,GO:0042470~melanosome,GO:0048471~perinuclear region of cytoplasm,GO:0070062~extracellular exosome,GO:0071682~endocytic vesicle lumen, GO:0003723~RNA binding,GO:0005509~calcium ion binding,GO:0005515~protein binding,GO:0005524~ATP binding,GO:0019903~protein phosphatase binding,GO:0046790~virion binding,GO:0050750~low-density lipoprotein particle receptor binding,GO:0051082~unfolded protein binding, IPR001404:Heat shock protein Hsp90,IPR003594:Histidine kinase-like ATPase, ATP-binding domain,IPR019805:Heat shock protein Hsp90, conserved site,IPR020568:Ribosomal protein S5 domain 2-type fold,IPR020575:Heat shock protein Hsp90, N-terminal, hsa04141:Protein processing in endoplasmic reticulum,hsa04151:PI3K-Akt signaling pathway,hsa04915:Estrogen signaling pathway,hsa04918:Thyroid hormone synthesis,hsa05200:Pathways in cancer,hsa05215:Prostate cancer, PIRSF002583:heat shock protein, HSP90/HTPG types, SM00387:HATPase_c, 3D-structure,Acetylation,ATP-binding,Calcium,Chaperone,Coiled coil,Complete proteome,Direct protein sequencing,Disulfide bond,Endoplasmic reticulum,Glycoprotein,Nucleotide-binding,Phosphoprotein,Proteomics identification,Reference proteome,Signal,Stress response, binding site:ATP,binding site:ATP; via amide nitrogen,chain:Endoplasmin,disulfide bond,glycosylation site:N-linked (GlcNAc...),modified residue,sequence conflict,short sequence motif:Prevents secretion from ER,signal peptide, Q6NYU2 helicase with zinc finger(helz) Danio rerio GO:0006355~regulation of transcription, DNA-templated, GO:0005634~nucleus, GO:0000166~nucleotide binding,GO:0003677~DNA binding,GO:0003700~transcription factor activity, sequence-specific DNA binding,GO:0004386~helicase activity,GO:0005524~ATP binding,GO:0016787~hydrolase activity,GO:0046872~metal ion binding, IPR000571:Zinc finger, CCCH-type,IPR011539:Rel homology domain,IPR027417:P-loop containing nucleoside triphosphate hydrolase, SM00356:ZnF_C3H1, ATP-binding,Complete proteome,Helicase,Hydrolase,Metal-binding,Nucleotide-binding,Nucleus,Proteomics identification,Reference proteome,Zinc,Zinc-finger, chain:Probable helicase with zinc finger domain,nucleotide phosphate-binding region:ATP,short sequence motif:DEAA box,zinc finger region:C3H1-type, A2CG49 kalirin, RhoGEF kinase(Kalrn) Mus musculus GO:0001662~behavioral fear response,GO:0006468~protein phosphorylation,GO:0007266~Rho protein signal transduction,GO:0007399~nervous system development,GO:0007409~axonogenesis,GO:0007528~neuromuscular junction development,GO:0007595~lactation,GO:0007613~memory,GO:0008344~adult locomotory behavior,GO:0009612~response to mechanical stimulus,GO:0014909~smooth muscle cell migration,GO:0016310~phosphorylation,GO:0035023~regulation of Rho protein signal transduction,GO:0035176~social behavior,GO:0035556~intracellular signal transduction,GO:0042711~maternal behavior,GO:0043547~positive regulation of GTPase activity,GO:0046959~habituation,GO:0048148~behavioral response to cocaine,GO:0048168~regulation of neuronal synaptic plasticity,GO:0048659~smooth muscle cell proliferation,GO:0050773~regulation of dendrite development,GO:0051966~regulation of synaptic transmission, glutamatergic,GO:0060125~negative regulation of growth hormone secretion,GO:0060137~maternal process involved in parturition,GO:0060999~positive regulation of dendritic spine development,GO:0061003~positive regulation of dendritic spine morphogenesis,GO:0061368~behavioral response to formalin induced pain,GO:1900273~positive regulation of long-term synaptic potentiation,GO:1903076~regulation of protein localization to plasma membrane, GO:0005737~cytoplasm,GO:0005856~cytoskeleton,GO:0014069~postsynaptic density,GO:0043005~neuron projection,GO:0043025~neuronal cell body,GO:0048471~perinuclear region of cytoplasm,GO:0070062~extracellular exosome, GO:0000166~nucleotide binding,GO:0004672~protein kinase activity,GO:0004674~protein serine/threonine kinase activity,GO:0005085~guanyl-nucleotide exchange factor activity,GO:0005089~Rho guanyl-nucleotide exchange factor activity,GO:0005515~protein binding,GO:0005524~ATP binding,GO:0016301~kinase activity,GO:0016740~transferase activity,GO:0019899~enzyme binding,GO:0030676~Rac guanyl-nucleotide exchange factor activity,GO:0046872~metal ion binding, IPR000219:Dbl homology (DH) domain,IPR000719:Protein kinase, catalytic domain,IPR001251:CRAL-TRIO domain,IPR001452:Src homology-3 domain,IPR001849:Pleckstrin homology domain,IPR002017:Spectrin repeat,IPR003598:Immunoglobulin subtype 2,IPR003599:Immunoglobulin subtype,IPR003961:Fibronectin, type III,IPR007110:Immunoglobulin-like domain,IPR008271:Serine/threonine-protein kinase, active site,IPR011009:Protein kinase-like domain,IPR011993:Pleckstrin homology-like domain,IPR013098:Immunoglobulin I-set,IPR013783:Immunoglobulin-like fold,IPR017441:Protein kinase, ATP binding site,IPR018159:Spectrin/alpha-actinin, SM00060:FN3,SM00150:SPEC,SM00220:S_TKc,SM00233:PH,SM00325:RhoGEF,SM00326:SH3,SM00408:IGc2,SM00409:IG,SM00516:SEC14, 3D-structure,Alternative initiation,Alternative splicing,ATP-binding,Coiled coil,Complete proteome,Cytoplasm,Cytoskeleton,Direct protein sequencing,Disulfide bond,Guanine-nucleotide releasing factor,Immunoglobulin domain,Kinase,Magnesium,Metal-binding,Nucleotide-binding,Phosphoprotein,Proteomics identification,Reference proteome,Repeat,Serine/threonine-protein kinase,SH3 domain,Transferase, active site:Proton acceptor,binding site:ATP,chain:Kalirin,compositionally biased region:Poly-Gln,disulfide bond,domain:CRAL-TRIO,domain:DH 1,domain:DH 2,domain:Fibronectin type-III,domain:Ig-like C2-type,domain:PH 1,domain:PH 2,domain:Protein kinase,domain:SH3 1,domain:SH3 2,modified residue,nucleotide phosphate-binding region:ATP,repeat:Spectrin 1,repeat:Spectrin 2,repeat:Spectrin 3,repeat:Spectrin 4,repeat:Spectrin 5,sequence conflict,splice variant,strand, O95198 kelch like family member 2(KLHL2) Homo sapiens GO:0016567~protein ubiquitination, GO:0001726~ruffle,GO:0005737~cytoplasm,GO:0005829~cytosol,GO:0015629~actin cytoskeleton,GO:0016021~integral component of membrane,GO:0030027~lamellipodium,GO:0031463~Cul3-RING ubiquitin ligase complex, GO:0003779~actin binding,GO:0004842~ubiquitin-protein transferase activity,GO:0005515~protein binding,GO:0042802~identical protein binding, IPR000210:BTB/POZ-like,IPR006652:Kelch repeat type 1,IPR011333:BTB/POZ fold,IPR011705:BTB/Kelch-associated,IPR015916:Galactose oxidase, beta-propeller,IPR017096:Kelch-like protein, gigaxonin, PIRSF037037:kelch-like protein, gigaxonin type, SM00225:BTB,SM00612:Kelch,SM00875:SM00875, 3D-structure,Actin-binding,Alternative splicing,Cell projection,Complete proteome,Cytoplasm,Cytoskeleton,Kelch repeat,Membrane,Reference proteome,Repeat,Transmembrane,Transmembrane helix,Ubl conjugation pathway, chain:Kelch-like protein 2,domain:BTB,repeat:Kelch 1,repeat:Kelch 2,repeat:Kelch 3,repeat:Kelch 4,repeat:Kelch 5,repeat:Kelch 6,sequence conflict, Q7T163 kinase D-interacting substrate 220b(kidins220b) Danio rerio General function prediction only, GO:0007399~nervous system development,GO:0038180~nerve growth factor signaling pathway,GO:0045859~regulation of protein kinase activity, GO:0005768~endosome,GO:0005770~late endosome,GO:0016020~membrane,GO:0016021~integral component of membrane, GO:0019887~protein kinase regulator activity,GO:0030165~PDZ domain binding, IPR002110:Ankyrin repeat,IPR011646:KAP P-loop,IPR020683:Ankyrin repeat-containing domain, SM00248:ANK, ANK repeat,Complete proteome,Endosome,Membrane,Neurogenesis,Proteomics identification,Reference proteome,Repeat,Transmembrane,Transmembrane helix, chain:Kinase D-interacting substrate of 220 kDa,domain:KAP NTPase,repeat:ANK 1,repeat:ANK 10,repeat:ANK 11,repeat:ANK 2,repeat:ANK 3,repeat:ANK 4,repeat:ANK 5,repeat:ANK 6,repeat:ANK 7,repeat:ANK 8,repeat:ANK 9,sequence conflict,topological domain:Cytoplasmic,topological domain:Exoplasmic loop,transmembrane region, Q96FN5 kinesin family member 12(KIF12) Homo sapiens GO:0007018~microtubule-based movement, GO:0005737~cytoplasm,GO:0005815~microtubule organizing center,GO:0005871~kinesin complex,GO:0005874~microtubule,GO:0070062~extracellular exosome, GO:0003777~microtubule motor activity,GO:0005524~ATP binding,GO:0008017~microtubule binding,GO:0016887~ATPase activity, IPR001752:Kinesin, motor domain,IPR019821:Kinesin, motor region, conserved site,IPR027417:P-loop containing nucleoside triphosphate hydrolase, SM00129:KISc, ATP-binding,Coiled coil,Complete proteome,Cytoplasm,Cytoskeleton,Microtubule,Motor protein,Nucleotide-binding,Phosphoprotein,Proteomics identification,Reference proteome, chain:Kinesin-like protein KIF12,compositionally biased region:Pro-rich,domain:Kinesin-motor,nucleotide phosphate-binding region:ATP, Q9D2Z8 kinesin family member 12(Kif12) Mus musculus GO:0007018~microtubule-based movement, GO:0005737~cytoplasm,GO:0005815~microtubule organizing center,GO:0005856~cytoskeleton,GO:0005871~kinesin complex,GO:0005874~microtubule,GO:0070062~extracellular exosome, GO:0000166~nucleotide binding,GO:0003777~microtubule motor activity,GO:0005524~ATP binding,GO:0008017~microtubule binding,GO:0016887~ATPase activity, IPR001752:Kinesin, motor domain,IPR019821:Kinesin, motor region, conserved site,IPR027417:P-loop containing nucleoside triphosphate hydrolase, SM00129:KISc, ATP-binding,Coiled coil,Complete proteome,Cytoplasm,Cytoskeleton,Microtubule,Motor protein,Nucleotide-binding,Phosphoprotein,Reference proteome, chain:Kinesin-like protein KIF12,compositionally biased region:Pro-rich,domain:Kinesin-motor,nucleotide phosphate-binding region:ATP,sequence conflict, Q9EQW7 kinesin family member 13A(Kif13a) Mus musculus GO:0000910~cytokinesis,GO:0006810~transport,GO:0006886~intracellular protein transport,GO:0007018~microtubule-based movement,GO:0007049~cell cycle,GO:0008333~endosome to lysosome transport,GO:0015031~protein transport,GO:0032438~melanosome organization,GO:0035459~cargo loading into vesicle,GO:0043001~Golgi to plasma membrane protein transport,GO:0051301~cell division,GO:0072383~plus-end-directed vesicle transport along microtubule, GO:0005622~intracellular,GO:0005623~cell,GO:0005737~cytoplasm,GO:0005768~endosome,GO:0005794~Golgi apparatus,GO:0005813~centrosome,GO:0005856~cytoskeleton,GO:0005871~kinesin complex,GO:0005874~microtubule,GO:0010008~endosome membrane,GO:0016020~membrane,GO:0030496~midbody,GO:0032588~trans-Golgi network membrane, GO:0000166~nucleotide binding,GO:0003777~microtubule motor activity,GO:0005515~protein binding,GO:0005524~ATP binding,GO:0008017~microtubule binding,GO:0016887~ATPase activity, IPR000253:Forkhead-associated (FHA) domain,IPR001752:Kinesin, motor domain,IPR008984:SMAD/FHA domain,IPR019821:Kinesin, motor region, conserved site,IPR022140:Kinesin protein 1B,IPR022164:Kinesin-like,IPR027417:P-loop containing nucleoside triphosphate hydrolase, SM00129:KISc, 3D-structure,ATP-binding,Cell cycle,Cell division,Coiled coil,Complete proteome,Cytoplasm,Cytoskeleton,Endosome,Golgi apparatus,Membrane,Microtubule,Motor protein,Nucleotide-binding,Phosphoprotein,Protein transport,Proteomics identification,Reference proteome,Transport, chain:Kinesin-like protein KIF13A,domain:FHA,domain:Kinesin-motor,modified residue,nucleotide phosphate-binding region:ATP,sequence conflict, B0W6M9 leucine-rich repeat protein SHOC-2(CpipJ_CPIJ002780) Culex quinquefasciatus IPR001611:Leucine-rich repeat,IPR003591:Leucine-rich repeat, typical subtype,IPR025875:Leucine rich repeat 4, SM00369:LRR_TYP, Complete proteome,Leucine-rich repeat,Reference proteome,Repeat, chain:Leucine-rich repeat protein soc-2 homolog,repeat:LRR 1,repeat:LRR 10,repeat:LRR 11,repeat:LRR 12,repeat:LRR 13,repeat:LRR 14,repeat:LRR 15,repeat:LRR 16,repeat:LRR 17,repeat:LRR 18,repeat:LRR 19,repeat:LRR 2,repeat:LRR 20,repeat:LRR 3,repeat:LRR 4,repeat:LRR 5,repeat:LRR 6,repeat:LRR 7,repeat:LRR 8,repeat:LRR 9, Q86XE3 mitochondrial calcium uptake family member 3(MICU3) Homo sapiens GO:0005739~mitochondrion,GO:0016021~integral component of membrane, GO:0005509~calcium ion binding, IPR002048:EF-hand domain,IPR011992:EF-hand-like domain,IPR018247:EF-Hand 1, calcium-binding site, SM00054:EFh, Calcium,Complete proteome,Membrane,Metal-binding,Mitochondrion,Proteomics identification,Reference proteome,Repeat,Transmembrane,Transmembrane helix, calcium-binding region:1,calcium-binding region:2,chain:EF-hand domain-containing family member A2,compositionally biased region:Poly-Ala,compositionally biased region:Poly-Arg,domain:EF-hand 1,domain:EF-hand 2,domain:EF-hand 3,sequence conflict,transmembrane region, Q58DQ5 mitochondrial ribosomal protein S9(MRPS9) Bos taurus GO:0000462~maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA),GO:0006412~translation,GO:0070124~mitochondrial translational initiation,GO:0070125~mitochondrial translational elongation, GO:0005730~nucleolus,GO:0005743~mitochondrial inner membrane,GO:0005763~mitochondrial small ribosomal subunit, GO:0003735~structural constituent of ribosome,GO:0044822~poly(A) RNA binding, IPR000754:Ribosomal protein S9,IPR014721:Ribosomal protein S5 domain 2-type fold, subgroup,IPR020568:Ribosomal protein S5 domain 2-type fold,IPR020574:Ribosomal protein S9, conserved site, bta03010:Ribosome, 3D-structure,Alternative splicing,Complete proteome,Direct protein sequencing,Mitochondrion,Reference proteome,Ribonucleoprotein,Ribosomal protein,Transit peptide, chain:28S ribosomal protein S9, mitochondrial,modified residue,sequence conflict,splice variant,transit peptide:Mitochondrion, Q99MD8 myoneurin(Mynn) Mus musculus Transcription / Cell division and chromosome partitioning, GO:0006351~transcription, DNA-templated,GO:0006355~regulation of transcription, DNA-templated, GO:0005634~nucleus, GO:0003676~nucleic acid binding,GO:0003677~DNA binding,GO:0046872~metal ion binding, IPR000210:BTB/POZ-like,IPR007087:Zinc finger, C2H2,IPR011333:BTB/POZ fold,IPR013087:Zinc finger C2H2-type/integrase DNA-binding domain,IPR015880:Zinc finger, C2H2-like, SM00225:BTB,SM00355:ZnF_C2H2, Alternative splicing,Complete proteome,DNA-binding,Metal-binding,Nucleus,Reference proteome,Repeat,Transcription,Transcription regulation,Zinc,Zinc-finger, chain:Myoneurin,compositionally biased region:Poly-Lys,domain:BTB,sequence conflict,short sequence motif:Nuclear localization signal,splice variant,zinc finger region:C2H2-type 1,zinc finger region:C2H2-type 2,zinc finger region:C2H2-type 3,zinc finger region:C2H2-type 4,zinc finger region:C2H2-type 5,zinc finger region:C2H2-type 6,zinc finger region:C2H2-type 7,zinc finger region:C2H2-type 8, Q8K4Q6 nei endonuclease VIII-like 1 (E. coli)(Neil1) Mus musculus GO:0006281~DNA repair,GO:0006284~base-excision repair,GO:0006289~nucleotide-excision repair,GO:0006974~cellular response to DNA damage stimulus,GO:0006979~response to oxidative stress,GO:0008152~metabolic process,GO:0032074~negative regulation of nuclease activity, GO:0005634~nucleus,GO:0005694~chromosome,GO:0005737~cytoplasm,GO:0005815~microtubule organizing center,GO:0005856~cytoskeleton, GO:0003676~nucleic acid binding,GO:0003677~DNA binding,GO:0003684~damaged DNA binding,GO:0003824~catalytic activity,GO:0003906~DNA-(apurinic or apyrimidinic site) lyase activity,GO:0008022~protein C-terminus binding,GO:0008270~zinc ion binding,GO:0016787~hydrolase activity,GO:0016798~hydrolase activity, acting on glycosyl bonds,GO:0016799~hydrolase activity, hydrolyzing N-glycosyl compounds,GO:0016829~lyase activity,GO:0019104~DNA N-glycosylase activity, IPR010979:Ribosomal protein S13-like, H2TH,IPR012319:DNA glycosylase/AP lyase, catalytic domain,IPR015371:Endonuclease VIII-like 1, DNA binding,IPR015886:DNA glycosylase/AP lyase, H2TH DNA-binding, mmu03410:Base excision repair, SM00898:SM00898,SM01232:SM01232, Alternative splicing,Chromosome,Complete proteome,Cytoplasm,Cytoskeleton,DNA damage,DNA repair,DNA-binding,Glycosidase,Hydrolase,Lyase,Multifunctional enzyme,Nucleus,Reference proteome, active site:Proton donor,active site:Proton donor; for beta-elimination activity,active site:Schiff-base intermediate with DNA,binding site:DNA,chain:Endonuclease VIII-like 1,splice variant, O42101 nuclear receptor subfamily 5, group A, member 2(NR5A2) Gallus gallus GO:0006351~transcription, DNA-templated,GO:0008206~bile acid metabolic process,GO:0009755~hormone-mediated signaling pathway,GO:0009888~tissue development,GO:0030522~intracellular receptor signaling pathway,GO:0030855~epithelial cell differentiation,GO:0042127~regulation of cell proliferation,GO:0042632~cholesterol homeostasis,GO:0043401~steroid hormone mediated signaling pathway,GO:0045070~positive regulation of viral genome replication,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,GO:0061113~pancreas morphogenesis, GO:0005634~nucleus,GO:0005737~cytoplasm,GO:0090575~RNA polymerase II transcription factor complex, GO:0000976~transcription regulatory region sequence-specific DNA binding,GO:0000978~RNA polymerase II core promoter proximal region sequence-specific DNA binding,GO:0000980~RNA polymerase II distal enhancer sequence-specific DNA binding,GO:0001077~transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding,GO:0003682~chromatin binding,GO:0003700~transcription factor activity, sequence-specific DNA binding,GO:0003707~steroid hormone receptor activity,GO:0004879~RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding,GO:0005543~phospholipid binding,GO:0008270~zinc ion binding,GO:0043565~sequence-specific DNA binding, IPR000536:Nuclear hormone receptor, ligand-binding, core,IPR001628:Zinc finger, nuclear hormone receptor-type,IPR001723:Steroid hormone receptor,IPR013088:Zinc finger, NHR/GATA-type,IPR016355:Steroidogenic factor 1, PIRSF002530:steroidogenic factor-like nuclear receptor, SM00399:ZnF_C4,SM00430:HOLI, Complete proteome,DNA-binding,Metal-binding,Nucleus,Receptor,Reference proteome,Transcription,Transcription regulation,Zinc,Zinc-finger, chain:Nuclear receptor subfamily 5 group A member 2,DNA-binding region:Nuclear receptor,region of interest:Ligand-binding,short sequence motif:FTZ-F1 box,zinc finger region:NR C4-type, Q6NRY2 nucleolar protein 6 L homeolog(nol6.L) Xenopus laevis GO:0005730~nucleolus, GO:0003723~RNA binding, IPR005554:Nrap protein, xla03008:Ribosome biogenesis in eukaryotes, Nucleus,RNA-binding, chain:Nucleolar protein 6, Q7T3C6 nudix hydrolase 21(nudt21) Danio rerio GO:0006378~mRNA polyadenylation,GO:0006397~mRNA processing, GO:0005634~nucleus,GO:0005849~mRNA cleavage factor complex,GO:0042382~paraspeckles, GO:0003723~RNA binding,GO:0003729~mRNA binding,GO:0016787~hydrolase activity,GO:0017091~AU-rich element binding, IPR000086:NUDIX hydrolase domain,IPR015797:NUDIX hydrolase domain-like,IPR016706:Cleavage/polyadenylation specificity factor subunit 5, dre03015:mRNA surveillance pathway, PIRSF017888:cleavage and polyadenylation specificity factor subunit 5, Complete proteome,mRNA processing,Nucleus,Reference proteome,RNA-binding, chain:Cleavage and polyadenylation specificity factor subunit 5,domain:Nudix hydrolase,short sequence motif:Nudix box, Q8CI95 oxysterol binding protein-like 11(Osbpl11) Mus musculus GO:0006810~transport,GO:0006869~lipid transport,GO:0010890~positive regulation of sequestering of triglyceride,GO:0045444~fat cell differentiation, GO:0005768~endosome,GO:0005794~Golgi apparatus,GO:0016020~membrane,GO:0031902~late endosome membrane, GO:0008289~lipid binding, IPR000648:Oxysterol-binding protein,IPR001849:Pleckstrin homology domain,IPR011993:Pleckstrin homology-like domain,IPR018494:Oxysterol-binding protein, conserved site, SM00233:PH, Acetylation,Complete proteome,Endosome,Golgi apparatus,Lipid transport,Lipid-binding,Membrane,Phosphoprotein,Proteomics identification,Reference proteome,Transport, chain:Oxysterol-binding protein-related protein 11,domain:PH,modified residue, O75439 peptidase, mitochondrial processing beta subunit(PMPCB) Homo sapiens General function prediction only, GO:0006122~mitochondrial electron transport, ubiquinol to cytochrome c,GO:0009060~aerobic respiration,GO:0016485~protein processing, GO:0005750~mitochondrial respiratory chain complex III,GO:0005759~mitochondrial matrix, GO:0003824~catalytic activity,GO:0004222~metalloendopeptidase activity,GO:0008270~zinc ion binding,GO:0046872~metal ion binding, IPR001431:Peptidase M16, zinc-binding site,IPR007863:Peptidase M16, C-terminal domain,IPR011237:Peptidase M16 domain,IPR011249:Metalloenzyme, LuxS/M16 peptidase-like,IPR011765:Peptidase M16, N-terminal, Complete proteome,Direct protein sequencing,Hydrolase,Metal-binding,Metalloprotease,Mitochondrion,Polymorphism,Protease,Proteomics identification,Reference proteome,Transit peptide,Zinc, active site:Proton acceptor,chain:Mitochondrial-processing peptidase subunit beta,metal ion-binding site:Zinc,sequence conflict,sequence variant,transit peptide:Mitochondrion, P08478 peptidylglycine alpha-amidating monooxygenase L homeolog(pam.L) Xenopus laevis Function unknown, GO:0006518~peptide metabolic process, GO:0016021~integral component of membrane,GO:0030658~transport vesicle membrane, GO:0004504~peptidylglycine monooxygenase activity,GO:0004598~peptidylamidoglycolate lyase activity,GO:0005507~copper ion binding, IPR000323:Copper type II, ascorbate-dependent monooxygenase, N-terminal,IPR000720:Peptidyl-glycine alpha-amidating monooxygenase,IPR001258:NHL repeat,IPR008977:PHM/PNGase F domain,IPR011042:Six-bladed beta-propeller, TolB-like,IPR013017:NHL repeat, subgroup,IPR014783:Copper type II, ascorbate-dependent monooxygenase, histidine-cluster-2 conserved site,IPR014784:Copper type II, ascorbate-dependent monooxygenase-like, C-terminal,IPR020611:Copper type II, ascorbate-dependent monooxygenase, histidine-cluster-1 conserved site, Alternative splicing,Copper,Cytoplasmic vesicle,Direct protein sequencing,Disulfide bond,Glycoprotein,Lyase,Membrane,Metal-binding,Monooxygenase,Multifunctional enzyme,Oxidoreductase,Repeat,Signal,Transmembrane,Transmembrane helix,Zinc, chain:Peptidyl-glycine alpha-amidating monooxygenase A,disulfide bond,glycosylation site:N-linked (GlcNAc...),metal ion-binding site:Copper A,metal ion-binding site:Copper B,region of interest:Peptidyl-alpha-hydroxyglycine alpha- amidating lyase,region of interest:Peptidylglycine alpha-hydroxylating monooxygenase,repeat:NHL 1,repeat:NHL 2,repeat:NHL 3,repeat:NHL 4,signal peptide,splice variant,topological domain:Cytoplasmic,topological domain:Intragranular,transmembrane region, P14925 peptidylglycine alpha-amidating monooxygenase(Pam) Rattus norvegicus Function unknown, GO:0001519~peptide amidation,GO:0001666~response to hypoxia,GO:0001676~long-chain fatty acid metabolic process,GO:0006357~regulation of transcription from RNA polymerase II promoter,GO:0006518~peptide metabolic process,GO:0007417~central nervous system development,GO:0007507~heart development,GO:0007595~lactation,GO:0009268~response to pH,GO:0009404~toxin metabolic process,GO:0018032~protein amidation,GO:0019538~protein metabolic process,GO:0022602~ovulation cycle process,GO:0032355~response to estradiol,GO:0032956~regulation of actin cytoskeleton organization,GO:0042476~odontogenesis,GO:0042493~response to drug,GO:0046688~response to copper ion,GO:0050708~regulation of protein secretion,GO:0051260~protein homooligomerization,GO:0051384~response to glucocorticoid,GO:0055114~oxidation-reduction process,GO:0060135~maternal process involved in female pregnancy,GO:0060173~limb development, GO:0005615~extracellular space,GO:0005802~trans-Golgi network,GO:0005886~plasma membrane,GO:0009986~cell surface,GO:0016020~membrane,GO:0016021~integral component of membrane,GO:0030141~secretory granule,GO:0030658~transport vesicle membrane,GO:0030667~secretory granule membrane,GO:0043005~neuron projection,GO:0043025~neuronal cell body,GO:0043204~perikaryon,GO:0048471~perinuclear region of cytoplasm,GO:0070062~extracellular exosome, GO:0004504~peptidylglycine monooxygenase activity,GO:0004598~peptidylamidoglycolate lyase activity,GO:0005507~copper ion binding,GO:0005509~calcium ion binding,GO:0005515~protein binding,GO:0008270~zinc ion binding,GO:0019901~protein kinase binding,GO:0031418~L-ascorbic acid binding, IPR000323:Copper type II, ascorbate-dependent monooxygenase, N-terminal,IPR000720:Peptidyl-glycine alpha-amidating monooxygenase,IPR001258:NHL repeat,IPR008977:PHM/PNGase F domain,IPR011042:Six-bladed beta-propeller, TolB-like,IPR013017:NHL repeat, subgroup,IPR014783:Copper type II, ascorbate-dependent monooxygenase, histidine-cluster-2 conserved site,IPR014784:Copper type II, ascorbate-dependent monooxygenase-like, C-terminal,IPR020611:Copper type II, ascorbate-dependent monooxygenase, histidine-cluster-1 conserved site, 3D-structure,Alternative splicing,Cleavage on pair of basic residues,Complete proteome,Copper,Cytoplasmic vesicle,Direct protein sequencing,Disulfide bond,Glycoprotein,Lyase,Membrane,Metal-binding,Monooxygenase,Multifunctional enzyme,Oxidoreductase,Phosphoprotein,Reference proteome,Repeat,Signal,Sulfation,Transmembrane,Transmembrane helix,Vitamin C,Zinc, chain:Peptidyl-glycine alpha-amidating monooxygenase,disulfide bond,glycosylation site:N-linked (GlcNAc...),helix,metal ion-binding site:Copper A,metal ion-binding site:Copper B,modified residue,region of interest:Interaction with RASSF9,region of interest:Peptidyl-alpha-hydroxyglycine alpha- amidating lyase,region of interest:Peptidylglycine alpha-hydroxylating monooxygenase,repeat:NHL 1,repeat:NHL 2,repeat:NHL 3,repeat:NHL 4,repeat:NHL 5,sequence conflict,signal peptide,splice variant,strand,topological domain:Cytoplasmic,topological domain:Intragranular,transmembrane region,turn, Q9D787 peptidylprolyl isomerase (cyclophilin)-like 2(Ppil2) Mus musculus GO:0000209~protein polyubiquitination,GO:0000413~protein peptidyl-prolyl isomerization,GO:0006457~protein folding,GO:0016567~protein ubiquitination,GO:0072659~protein localization to plasma membrane, GO:0005634~nucleus,GO:0005654~nucleoplasm,GO:0005737~cytoplasm,GO:0005886~plasma membrane, GO:0003755~peptidyl-prolyl cis-trans isomerase activity,GO:0004842~ubiquitin-protein transferase activity,GO:0016853~isomerase activity,GO:0016874~ligase activity,GO:0034450~ubiquitin-ubiquitin ligase activity,GO:0061630~ubiquitin protein ligase activity, IPR002130:Cyclophilin-like peptidyl-prolyl cis-trans isomerase domain,IPR003613:U box domain,IPR013083:Zinc finger, RING/FYVE/PHD-type,IPR020892:Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site,IPR024936:Cyclophilin-type peptidyl-prolyl cis-trans isomerase, mmu04120:Ubiquitin mediated proteolysis, SM00504:Ubox, Acetylation,Coiled coil,Complete proteome,Isomerase,Ligase,Nucleus,Proteomics identification,Reference proteome,Rotamase,Ubl conjugation pathway, chain:Peptidyl-prolyl cis-trans isomerase-like 2,domain:PPIase cyclophilin-type,domain:U-box,modified residue,sequence conflict, Q969N2 phosphatidylinositol glycan anchor biosynthesis class T(PIGT) Homo sapiens GO:0016255~attachment of GPI anchor to protein,GO:0030182~neuron differentiation,GO:0051402~neuron apoptotic process, GO:0005789~endoplasmic reticulum membrane,GO:0016020~membrane,GO:0016023~cytoplasmic, membrane-bounded vesicle,GO:0030176~integral component of endoplasmic reticulum membrane,GO:0042765~GPI-anchor transamidase complex, GO:0003923~GPI-anchor transamidase activity,GO:0005515~protein binding, IPR007245:GPI transamidase component PIG-T, hsa00563:Glycosylphosphatidylinositol(GPI)-anchor biosynthesis,hsa01100:Metabolic pathways, 615398~Multiple congenital anomalies-hypotonia-seizures syndrome 3,615399~Paroxysmal nocturnal hemoglobinuria 2, Alternative splicing,Complete proteome,Direct protein sequencing,Disease mutation,Disulfide bond,Endoplasmic reticulum,Epilepsy,Glycoprotein,GPI-anchor biosynthesis,Membrane,Polymorphism,Proteomics identification,Reference proteome,Signal,Transmembrane,Transmembrane helix, chain:GPI transamidase component PIG-T,disulfide bond,glycosylation site:N-linked (GlcNAc...),mutagenesis site,sequence variant,signal peptide,splice variant,topological domain:Cytoplasmic,topological domain:Lumenal,transmembrane region, Q803C9 phosphatidylserine synthase 1a(ptdss1a) Danio rerio GO:0006629~lipid metabolic process,GO:0006659~phosphatidylserine biosynthetic process,GO:0008654~phospholipid biosynthetic process, GO:0005783~endoplasmic reticulum,GO:0005789~endoplasmic reticulum membrane,GO:0016020~membrane,GO:0016021~integral component of membrane, GO:0016740~transferase activity, IPR004277:Phosphatidyl serine synthase, dre00564:Glycerophospholipid metabolism,dre01100:Metabolic pathways, Complete proteome,Endoplasmic reticulum,Lipid biosynthesis,Lipid metabolism,Membrane,Phospholipid biosynthesis,Phospholipid metabolism,Reference proteome,Transferase,Transmembrane,Transmembrane helix, Q9JMB7 piwi-like RNA-mediated gene silencing 1(Piwil1) Mus musculus GO:0000239~pachytene,GO:0006417~regulation of translation,GO:0007275~multicellular organism development,GO:0007283~spermatogenesis,GO:0007286~spermatid development,GO:0030154~cell differentiation,GO:0031047~gene silencing by RNA,GO:0034587~piRNA metabolic process,GO:0051321~meiotic cell cycle, GO:0005634~nucleus,GO:0005737~cytoplasm,GO:0005829~cytosol,GO:0005844~polysome,GO:0005845~mRNA cap binding complex,GO:0033391~chromatoid body,GO:0043186~P granule,GO:0097433~dense body, GO:0003676~nucleic acid binding,GO:0003723~RNA binding,GO:0003727~single-stranded RNA binding,GO:0003729~mRNA binding,GO:0005515~protein binding,GO:0019901~protein kinase binding,GO:0034584~piRNA binding, IPR003100:Argonaute/Dicer protein, PAZ,IPR003165:Stem cell self-renewal protein Piwi,IPR012337:Ribonuclease H-like domain,IPR014811:Domain of unknown function DUF1785, mmu04320:Dorso-ventral axis formation, SM00949:SM00949,SM00950:SM00950,SM01379:SM01379, 3D-structure,Alternative splicing,Complete proteome,Cytoplasm,Developmental protein,Differentiation,Meiosis,Methylation,Proteomics identification,Reference proteome,RNA-binding,RNA-mediated gene silencing,Spermatogenesis,Translation regulation, chain:Piwi-like protein 1,domain:PAZ,domain:Piwi,modified residue,region of interest:RNA-binding,sequence conflict,splice variant, Q460N5 poly(ADP-ribose) polymerase family member 14(PARP14) Homo sapiens GO:0006351~transcription, DNA-templated,GO:0006355~regulation of transcription, DNA-templated, GO:0005634~nucleus,GO:0005737~cytoplasm,GO:0016020~membrane, GO:0003950~NAD+ ADP-ribosyltransferase activity, IPR002589:Appr-1-p processing,IPR004170:WWE domain,IPR012317:Poly(ADP-ribose) polymerase, catalytic domain, SM00506:A1pp, 3D-structure,Alternative splicing,Complete proteome,Cytoplasm,Glycosyltransferase,NAD,Nucleus,Phosphoprotein,Proteomics identification,Reference proteome,Repeat,Transcription,Transcription regulation,Transferase, chain:Poly [ADP-ribose] polymerase 14,domain:Macro 1,domain:Macro 2,domain:Macro 3,domain:PARP catalytic,domain:WWE,helix,sequence conflict,splice variant,strand,turn, Q9UKK3 poly(ADP-ribose) polymerase family member 4(PARP4) Homo sapiens GO:0006281~DNA repair,GO:0006464~cellular protein modification process,GO:0006471~protein ADP-ribosylation,GO:0006810~transport,GO:0006954~inflammatory response,GO:0006974~cellular response to DNA damage stimulus,GO:0008219~cell death,GO:0042493~response to drug, GO:0005634~nucleus,GO:0005737~cytoplasm,GO:0005876~spindle microtubule,GO:0016020~membrane,GO:0030529~intracellular ribonucleoprotein complex,GO:0070062~extracellular exosome, GO:0003677~DNA binding,GO:0003950~NAD+ ADP-ribosyltransferase activity,GO:0005515~protein binding,GO:0019899~enzyme binding, IPR001357:BRCT domain,IPR002035:von Willebrand factor, type A,IPR004102:Poly(ADP-ribose) polymerase, regulatory domain,IPR012317:Poly(ADP-ribose) polymerase, catalytic domain,IPR013694:VIT domain, hsa03410:Base excision repair, SM00292:BRCT,SM00327:VWA,SM00609:VIT, Complete proteome,Cytoplasm,Cytoskeleton,Direct protein sequencing,Glycosyltransferase,Methylation,NAD,Nucleus,Phosphoprotein,Polymorphism,Reference proteome,Ribonucleoprotein,Transferase, chain:Poly [ADP-ribose] polymerase 4,domain:BRCT,domain:PARP alpha-helical,domain:PARP catalytic,domain:VIT,domain:VWFA,modified residue,region of interest:Interaction with the major vault protein,sequence conflict,sequence variant,short sequence motif:Nuclear localization signal, A2A559 post-GPI attachment to proteins 3(Pgap3) Mus musculus GO:0006505~GPI anchor metabolic process,GO:0006506~GPI anchor biosynthetic process, GO:0000139~Golgi membrane,GO:0005783~endoplasmic reticulum,GO:0005794~Golgi apparatus,GO:0016020~membrane,GO:0016021~integral component of membrane,GO:0031227~intrinsic component of endoplasmic reticulum membrane, GO:0016788~hydrolase activity, acting on ester bonds, IPR007217:Per1-like, Alternative splicing,Complete proteome,Endoplasmic reticulum,Glycoprotein,Golgi apparatus,GPI-anchor biosynthesis,Membrane,Reference proteome,Signal,Transmembrane,Transmembrane helix, chain:Post-GPI attachment to proteins factor 3,glycosylation site:N-linked (GlcNAc...),sequence conflict,signal peptide,splice variant,topological domain:Cytoplasmic,topological domain:Lumenal,transmembrane region, Q5ZJ85 pre-mRNA processing factor 3(PRPF3) Gallus gallus GO:0000244~spliceosomal tri-snRNP complex assembly,GO:0000398~mRNA splicing, via spliceosome, GO:0005634~nucleus,GO:0005681~spliceosomal complex,GO:0005737~cytoplasm,GO:0015030~Cajal body,GO:0016607~nuclear speck,GO:0046540~U4/U6 x U5 tri-snRNP complex, GO:0044822~poly(A) RNA binding, IPR002483:PWI domain,IPR010541:Domain of unknown function DUF1115,IPR013881:Pre-mRNA-splicing factor 3,IPR027104:U4/U6 small nuclear ribonucleoprotein Prp3, gga03040:Spliceosome, SM00311:PWI, Complete proteome,mRNA processing,mRNA splicing,Nucleus,Phosphoprotein,Reference proteome,Spliceosome, chain:U4/U6 small nuclear ribonucleoprotein PRP3,compositionally biased region:Poly-Val,domain:PWI, O75400 pre-mRNA processing factor 40 homolog A(PRPF40A) Homo sapiens RNA processing and modification, GO:0000398~mRNA splicing, via spliceosome,GO:0007010~cytoskeleton organization,GO:0007049~cell cycle,GO:0008360~regulation of cell shape,GO:0016477~cell migration,GO:0032465~regulation of cytokinesis,GO:0051301~cell division, GO:0005654~nucleoplasm,GO:0005685~U1 snRNP,GO:0005737~cytoplasm,GO:0016020~membrane,GO:0016363~nuclear matrix,GO:0016607~nuclear speck,GO:0071004~U2-type prespliceosome, GO:0003723~RNA binding,GO:0005515~protein binding,GO:0044822~poly(A) RNA binding,GO:0070064~proline-rich region binding, IPR001202:WW domain,IPR002713:FF domain, hsa03040:Spliceosome, SM00441:FF,SM00456:WW, 3D-structure,Acetylation,Alternative splicing,Cell cycle,Cell division,Complete proteome,Isopeptide bond,Methylation,mRNA processing,mRNA splicing,Nucleus,Phosphoprotein,Proteomics identification,Reference proteome,Repeat,Ubl conjugation, chain:Pre-mRNA-processing factor 40 homolog A,domain:FF 1,domain:FF 2,domain:FF 3,domain:FF 4,domain:FF 5,domain:WW 1,domain:WW 2,helix,modified residue,sequence conflict,splice variant,strand,turn, Q32L99 prostaglandin reductase 2(PTGR2) Bos taurus General function prediction only, GO:0006693~prostaglandin metabolic process,GO:0055114~oxidation-reduction process, GO:0005739~mitochondrion, GO:0008270~zinc ion binding,GO:0016491~oxidoreductase activity,GO:0036132~13-prostaglandin reductase activity,GO:0047522~15-oxoprostaglandin 13-oxidase activity, IPR002085:Alcohol dehydrogenase superfamily, zinc-type,IPR011032:GroES-like,IPR013149:Alcohol dehydrogenase, C-terminal,IPR016040:NAD(P)-binding domain, Complete proteome,Cytoplasm,NADP,Oxidoreductase,Reference proteome, chain:Prostaglandin reductase 2,nucleotide phosphate-binding region:NADP, P57096 prostate stem cell antigen(Psca) Mus musculus GO:0005886~plasma membrane,GO:0016020~membrane,GO:0031225~anchored component of membrane,GO:0070062~extracellular exosome, IPR016054:Ly-6 antigen / uPA receptor -like,IPR018363:CD59 antigen, conserved site, SM00134:LU, Cell membrane,Complete proteome,Disulfide bond,Glycoprotein,GPI-anchor,Lipoprotein,Membrane,Reference proteome,Signal, chain:Prostate stem cell antigen,disulfide bond,domain:UPAR/Ly6,glycosylation site:N-linked (GlcNAc...),lipid moiety-binding region:GPI-anchor amidated asparagine,propeptide:Removed in mature form,signal peptide, Q4N4N8 protein disulfide isomerase(TP02_0602) Theileria parva strain Muguga GO:0045454~cell redox homeostasis, GO:0005789~endoplasmic reticulum membrane,GO:0016021~integral component of membrane, IPR012336:Thioredoxin-like fold,IPR013766:Thioredoxin domain, Complete proteome,Disulfide bond,Endoplasmic reticulum,Membrane,Redox-active center,Reference proteome,Signal,Transmembrane,Transmembrane helix, chain:Thioredoxin domain-containing protein,disulfide bond,domain:Thioredoxin,short sequence motif:Di-lysine motif,signal peptide,topological domain:Cytoplasmic,topological domain:Lumenal,transmembrane region, Q91WG5 protein kinase, AMP-activated, gamma 2 non-catalytic subunit(Prkag2) Mus musculus GO:0005977~glycogen metabolic process,GO:0006110~regulation of glycolytic process,GO:0006469~negative regulation of protein kinase activity,GO:0006629~lipid metabolic process,GO:0006631~fatty acid metabolic process,GO:0006633~fatty acid biosynthetic process,GO:0007005~mitochondrion organization,GO:0010800~positive regulation of peptidyl-threonine phosphorylation,GO:0019217~regulation of fatty acid metabolic process,GO:0035556~intracellular signal transduction,GO:0045860~positive regulation of protein kinase activity,GO:0050790~regulation of catalytic activity,GO:0061024~membrane organization, GO:0005615~extracellular space,GO:0005654~nucleoplasm,GO:0005829~cytosol,GO:0031588~nucleotide-activated protein kinase complex, GO:0000166~nucleotide binding,GO:0004679~AMP-activated protein kinase activity,GO:0004862~cAMP-dependent protein kinase inhibitor activity,GO:0005524~ATP binding,GO:0008603~cAMP-dependent protein kinase regulator activity,GO:0008607~phosphorylase kinase regulator activity,GO:0016208~AMP binding,GO:0016301~kinase activity,GO:0019901~protein kinase binding,GO:0030295~protein kinase activator activity,GO:0043531~ADP binding, IPR000644:Cystathionine beta-synthase, core, mmu04068:FoxO signaling pathway,mmu04152:AMPK signaling pathway,mmu04710:Circadian rhythm,mmu04910:Insulin signaling pathway,mmu04920:Adipocytokine signaling pathway,mmu04921:Oxytocin signaling pathway,mmu04922:Glucagon signaling pathway,mmu04931:Insulin resistance,mmu04932:Non-alcoholic fatty liver disease (NAFLD),mmu05410:Hypertrophic cardiomyopathy (HCM), SM00116:CBS, Alternative splicing,ATP-binding,CBS domain,Complete proteome,Fatty acid biosynthesis,Fatty acid metabolism,Kinase,Lipid biosynthesis,Lipid metabolism,Nucleotide-binding,Phosphoprotein,Proteomics identification,Reference proteome,Repeat,Transferase, chain:5'-AMP-activated protein kinase subunit gamma-2,domain:CBS 1,domain:CBS 2,domain:CBS 3,domain:CBS 4,modified residue,sequence conflict,splice variant, Q92932 protein tyrosine phosphatase, receptor type N2(PTPRN2) Homo sapiens GO:0006470~protein dephosphorylation,GO:0006629~lipid metabolic process,GO:0007269~neurotransmitter secretion,GO:0034260~negative regulation of GTPase activity,GO:0035335~peptidyl-tyrosine dephosphorylation,GO:0035773~insulin secretion involved in cellular response to glucose stimulus, GO:0005788~endoplasmic reticulum lumen,GO:0005887~integral component of plasma membrane,GO:0016021~integral component of membrane,GO:0030054~cell junction,GO:0030667~secretory granule membrane,GO:0030672~synaptic vesicle membrane,GO:0043195~terminal bouton,GO:0043235~receptor complex, GO:0004725~protein tyrosine phosphatase activity,GO:0005001~transmembrane receptor protein tyrosine phosphatase activity, IPR000242:Protein-tyrosine phosphatase, receptor/non-receptor type,IPR000387:Protein-tyrosine/Dual specificity phosphatase,IPR003595:Protein-tyrosine phosphatase, catalytic,IPR016130:Protein-tyrosine phosphatase, active site,IPR021613:Protein-tyrosine phosphatase receptor IA-2, hsa04940:Type I diabetes mellitus, SM00194:PTPc,SM00404:PTPc_motif, 3D-structure,Acetylation,Alternative splicing,Cell junction,Complete proteome,Cytoplasmic vesicle,Diabetes mellitus,Glycoprotein,Hydrolase,Lipid metabolism,Membrane,Phospholipid metabolism,Phosphoprotein,Polymorphism,Protein phosphatase,Proteomics identification,Receptor,Reference proteome,Signal,Synapse,Transmembrane,Transmembrane helix, active site:Phosphocysteine intermediate,chain:Receptor-type tyrosine-protein phosphatase N2,domain:Tyrosine-protein phosphatase,glycosylation site:N-linked (GlcNAc...),helix,modified residue,mutagenesis site,sequence conflict,sequence variant,signal peptide,site:Cleavage,splice variant,strand,topological domain:Cytoplasmic,topological domain:Extracellular,transmembrane region,turn, Q99571 purinergic receptor P2X 4(P2RX4) Homo sapiens GO:0001894~tissue homeostasis,GO:0002028~regulation of sodium ion transport,GO:0006810~transport,GO:0007165~signal transduction,GO:0007596~blood coagulation,GO:0008217~regulation of blood pressure,GO:0010524~positive regulation of calcium ion transport into cytosol,GO:0010614~negative regulation of cardiac muscle hypertrophy,GO:0019228~neuronal action potential,GO:0019233~sensory perception of pain,GO:0032308~positive regulation of prostaglandin secretion,GO:0033198~response to ATP,GO:0034220~ion transmembrane transport,GO:0034405~response to fluid shear stress,GO:0035590~purinergic nucleotide receptor signaling pathway,GO:0042118~endothelial cell activation,GO:0045429~positive regulation of nitric oxide biosynthetic process,GO:0050850~positive regulation of calcium-mediated signaling,GO:0051260~protein homooligomerization,GO:0051899~membrane depolarization,GO:0051928~positive regulation of calcium ion transport,GO:0055117~regulation of cardiac muscle contraction,GO:0055119~relaxation of cardiac muscle,GO:0071318~cellular response to ATP,GO:0097190~apoptotic signaling pathway,GO:0098655~cation transmembrane transport, GO:0005639~integral component of nuclear inner membrane,GO:0005765~lysosomal membrane,GO:0005886~plasma membrane,GO:0005887~integral component of plasma membrane,GO:0014069~postsynaptic density,GO:0016020~membrane,GO:0030054~cell junction,GO:0043025~neuronal cell body,GO:0043195~terminal bouton,GO:0043197~dendritic spine,GO:0048471~perinuclear region of cytoplasm,GO:0070062~extracellular exosome, GO:0001614~purinergic nucleotide receptor activity,GO:0004931~extracellular ATP-gated cation channel activity,GO:0005102~receptor binding,GO:0005507~copper ion binding,GO:0005515~protein binding,GO:0005524~ATP binding,GO:0008144~drug binding,GO:0008270~zinc ion binding,GO:0042803~protein homodimerization activity,GO:0045296~cadherin binding, IPR001429:P2X purinoreceptor,IPR003047:P2X4 purinoceptor,IPR027309:P2X purinoreceptor extracellular domain, hsa04020:Calcium signaling pathway,hsa04080:Neuroactive ligand-receptor interaction, PIRSF005713:ATP-gated ion channel P2X4 receptor, Alternative splicing,Complete proteome,Disulfide bond,Glycoprotein,Ion channel,Ion transport,Ligand-gated ion channel,Membrane,Polymorphism,Proteomics identification,Receptor,Reference proteome,Transmembrane,Transmembrane helix,Transport, chain:P2X purinoceptor 4,glycosylation site:N-linked (GlcNAc...),modified residue,sequence conflict,sequence variant,topological domain:Cytoplasmic,topological domain:Extracellular,transmembrane region, E1C2U2 replication timing regulatory factor 1(RIF1) Gallus gallus GO:0019827~stem cell population maintenance,GO:2001034~positive regulation of double-strand break repair via nonhomologous end joining, GO:0000781~chromosome, telomeric region,GO:0001939~female pronucleus,GO:0001940~male pronucleus,GO:0005886~plasma membrane, IPR016024:Armadillo-type fold,IPR022031:Rap1-interacting factor 1 N-terminal, Complete proteome,Reference proteome, P02362 ribosomal protein S8(rps7) Xenopus laevis GO:0006412~translation, GO:0005840~ribosome, GO:0003735~structural constituent of ribosome, IPR000554:Ribosomal protein S7e, xla03010:Ribosome, Ribonucleoprotein,Ribosomal protein, chain:40S ribosomal protein S7,compositionally biased region:Arg/Lys-rich (basic), Q61909 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)(Runx1t1) Mus musculus GO:0006351~transcription, DNA-templated,GO:0006355~regulation of transcription, DNA-templated,GO:0010977~negative regulation of neuron projection development,GO:0045444~fat cell differentiation,GO:0045599~negative regulation of fat cell differentiation,GO:0045892~negative regulation of transcription, DNA-templated,GO:0051101~regulation of DNA binding, GO:0005634~nucleus,GO:0005654~nucleoplasm,GO:0005737~cytoplasm,GO:0005739~mitochondrion,GO:0016021~integral component of membrane,GO:0016363~nuclear matrix,GO:0017053~transcriptional repressor complex, GO:0003677~DNA binding,GO:0003700~transcription factor activity, sequence-specific DNA binding,GO:0003714~transcription corepressor activity,GO:0005515~protein binding,GO:0042803~protein homodimerization activity,GO:0046872~metal ion binding, IPR002893:Zinc finger, MYND-type,IPR003894:TAFH/NHR1,IPR013289:Eight-Twenty-One,IPR013290:Myeloid transforming gene on chromosome 8 (MTG8),IPR014896:NHR2-like, mmu05200:Pathways in cancer,mmu05202:Transcriptional misregulation in cancer,mmu05221:Acute myeloid leukemia, SM00549:TAFH, Coiled coil,Complete proteome,Cyclin,DNA-binding,Membrane,Metal-binding,Nucleus,Phosphoprotein,Proteomics identification,Reference proteome,Repressor,Transcription,Transcription regulation,Transmembrane,Transmembrane helix,Zinc,Zinc-finger, chain:Protein CBFA2T1,compositionally biased region:Poly-Pro,compositionally biased region:Poly-Ser,domain:TAFH,modified residue,region of interest:Important for oligomerization,zinc finger region:MYND-type, Q3T106 serine and arginine rich splicing factor 7(SRSF7) Bos taurus GO:0006397~mRNA processing,GO:0008380~RNA splicing,GO:0048025~negative regulation of mRNA splicing, via spliceosome,GO:0051028~mRNA transport, GO:0005654~nucleoplasm,GO:0005737~cytoplasm,GO:0070062~extracellular exosome, GO:0000166~nucleotide binding,GO:0008270~zinc ion binding,GO:0044822~poly(A) RNA binding, IPR000504:RNA recognition motif domain,IPR001878:Zinc finger, CCHC-type,IPR012677:Nucleotide-binding, alpha-beta plait, bta03040:Spliceosome,bta05168:Herpes simplex infection, SM00360:RRM, Acetylation,Complete proteome,Cytoplasm,Metal-binding,mRNA processing,mRNA splicing,mRNA transport,Nucleus,Phosphoprotein,Reference proteome,Repeat,Repressor,RNA-binding,Transport,Zinc,Zinc-finger, chain:Splicing factor, arginine/serine-rich 7,compositionally biased region:Arg/Ser-rich (RS domain),domain:RRM,modified residue,region of interest:6 X 8 AA repeats of R-R-S-R-S-X-S-X,repeat:1,repeat:2,repeat:3,repeat:4,repeat:5; approximate,repeat:6; approximate,zinc finger region:CCHC-type, Q6DRC0 seryl-tRNA synthetase(sars) Danio rerio GO:0001525~angiogenesis,GO:0001569~patterning of blood vessels,GO:0006418~tRNA aminoacylation for protein translation,GO:0006434~seryl-tRNA aminoacylation, GO:0005737~cytoplasm, GO:0000166~nucleotide binding,GO:0004812~aminoacyl-tRNA ligase activity,GO:0004828~serine-tRNA ligase activity,GO:0005524~ATP binding,GO:0016874~ligase activity, IPR002314:Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved domain,IPR002317:Serine-tRNA ligase, type1,IPR006195:Aminoacyl-tRNA synthetase, class II,IPR010978:tRNA-binding arm,IPR015866:Serine-tRNA synthetase, type1, N-terminal, dre00970:Aminoacyl-tRNA biosynthesis, PIRSF001529:serine-tRNA ligase, Aminoacyl-tRNA synthetase,Complete proteome,Ligase,Proteomics identification,Reference proteome, A8DZE7 short chain dehydrogenase/reductase family 42E, member 1(sdr42e1) Danio rerio Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism, GO:0006694~steroid biosynthetic process,GO:0055114~oxidation-reduction process, GO:0016020~membrane,GO:0016021~integral component of membrane, GO:0000252~C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity,GO:0003854~3-beta-hydroxy-delta5-steroid dehydrogenase activity,GO:0004033~aldo-keto reductase (NADP) activity,GO:0004448~isocitrate dehydrogenase activity,GO:0004495~mevaldate reductase activity,GO:0008875~gluconate dehydrogenase activity,GO:0016229~steroid dehydrogenase activity,GO:0016491~oxidoreductase activity,GO:0016616~oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor,GO:0018451~epoxide dehydrogenase activity,GO:0018452~5-exo-hydroxycamphor dehydrogenase activity,GO:0018453~2-hydroxytetrahydrofuran dehydrogenase activity,GO:0019152~acetoin dehydrogenase activity,GO:0032442~phenylcoumaran benzylic ether reductase activity,GO:0032866~D-xylose:NADP reductase activity,GO:0032867~L-arabinose:NADP reductase activity,GO:0033709~D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity,GO:0033764~steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor,GO:0033765~steroid dehydrogenase activity, acting on the CH-CH group of donors,GO:0034831~(R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity,GO:0034840~3-hydroxymenthone dehydrogenase activity,GO:0035380~very long-chain-3-hydroxyacyl-CoA dehydrogenase activity,GO:0035410~dihydrotestosterone 17-beta-dehydrogenase activity,GO:0043713~(R)-2-hydroxyisocaproate dehydrogenase activity,GO:0044103~L-arabinose 1-dehydrogenase (NADP+) activity,GO:0044105~L-xylulose reductase (NAD+) activity,GO:0048258~3-ketoglucose-reductase activity,GO:0051990~(R)-2-hydroxyglutarate dehydrogenase activity,GO:0052677~D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity, IPR002225:3-beta hydroxysteroid dehydrogenase/isomerase,IPR016040:NAD(P)-binding domain, Complete proteome,Membrane,NAD,Oxidoreductase,Reference proteome,Transmembrane,Transmembrane helix, active site:Proton acceptor,binding site:NAD,chain:Short chain dehydrogenase/reductase family 42E member 1,sequence conflict,transmembrane region, Q5ZJ75 solute carrier family 9 member A8(SLC9A8) Gallus gallus GO:0006885~regulation of pH,GO:0035725~sodium ion transmembrane transport,GO:0051453~regulation of intracellular pH,GO:0071805~potassium ion transmembrane transport,GO:1902600~hydrogen ion transmembrane transport, GO:0000139~Golgi membrane,GO:0005794~Golgi apparatus,GO:0016021~integral component of membrane, GO:0015385~sodium:proton antiporter activity,GO:0015386~potassium:proton antiporter activity, IPR004709:Na+/H+ exchanger,IPR006153:Cation/H+ exchanger,IPR018409:Na+/H+ exchanger, isoform 8, eukaryotic,IPR018422:Cation/H+ exchanger, CPA1 family, Antiport,Complete proteome,Golgi apparatus,Ion transport,Membrane,Reference proteome,Sodium,Sodium transport,Transmembrane,Transmembrane helix,Transport, chain:Sodium/hydrogen exchanger 8,transmembrane region, F1Q506 sorting nexin 10a(snx10a) Danio rerio GO:0001947~heart looping,GO:0006810~transport,GO:0006897~endocytosis,GO:0015031~protein transport,GO:0016050~vesicle organization,GO:0030030~cell projection organization,GO:0042384~cilium assembly,GO:0060271~cilium morphogenesis,GO:0061512~protein localization to cilium,GO:0070121~Kupffer's vesicle development,GO:0070986~left/right axis specification,GO:0071539~protein localization to centrosome, GO:0005737~cytoplasm,GO:0005768~endosome,GO:0005813~centrosome,GO:0005815~microtubule organizing center,GO:0005856~cytoskeleton,GO:0010008~endosome membrane,GO:0016020~membrane,GO:0019898~extrinsic component of membrane, GO:0008289~lipid binding,GO:0035091~phosphatidylinositol binding, IPR001683:Phox homologous domain, SM00312:PX, Alternative splicing,Cilium biogenesis/degradation,Complete proteome,Cytoplasm,Cytoskeleton,Endosome,Lipid-binding,Membrane,Protein transport,Reference proteome,Transport, Q08BC4 sperm-tail PG-rich repeat containing 2(stpg2) Danio rerio IPR010736:Sperm-tail PG-rich repeat, Complete proteome,Reference proteome,Repeat, chain:Uncharacterized protein C4orf37 homolog, Q8CHC4 synaptojanin 1(Synj1) Mus musculus m_ndkDynaminPathway:Endocytotic role of NDK, Phosphins and Dynamin, GO:0006836~neurotransmitter transport,GO:0007420~brain development,GO:0007612~learning,GO:0014015~positive regulation of gliogenesis,GO:0016082~synaptic vesicle priming,GO:0016191~synaptic vesicle uncoating,GO:0032526~response to retinoic acid,GO:0034097~response to cytokine,GO:0046488~phosphatidylinositol metabolic process,GO:0046855~inositol phosphate dephosphorylation,GO:0046856~phosphatidylinositol dephosphorylation,GO:0048015~phosphatidylinositol-mediated signaling,GO:0048260~positive regulation of receptor-mediated endocytosis,GO:0048488~synaptic vesicle endocytosis,GO:0048489~synaptic vesicle transport,GO:1903423~positive regulation of synaptic vesicle recycling,GO:1904980~positive regulation of endosome organization, GO:0005737~cytoplasm,GO:0005829~cytosol,GO:0005874~microtubule,GO:0012506~vesicle membrane,GO:0030117~membrane coat,GO:0030118~clathrin coat,GO:0030132~clathrin coat of coated pit,GO:0043005~neuron projection,GO:0043195~terminal bouton,GO:0043234~protein complex,GO:0097060~synaptic membrane,GO:0098793~presynapse, GO:0000166~nucleotide binding,GO:0003676~nucleic acid binding,GO:0003723~RNA binding,GO:0004438~phosphatidylinositol-3-phosphatase activity,GO:0004439~phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity,GO:0005515~protein binding,GO:0008022~protein C-terminus binding,GO:0017124~SH3 domain binding,GO:0032403~protein complex binding,GO:0034595~phosphatidylinositol phosphate 5-phosphatase activity,GO:0042578~phosphoric ester hydrolase activity,GO:0043812~phosphatidylinositol-4-phosphate phosphatase activity, IPR000300:Inositol polyphosphate-related phosphatase,IPR000504:RNA recognition motif domain,IPR002013:Synaptojanin, N-terminal,IPR005135:Endonuclease/exonuclease/phosphatase,IPR012677:Nucleotide-binding, alpha-beta plait,IPR015047:Domain of unknown function DUF1866, mmu00562:Inositol phosphate metabolism,mmu01100:Metabolic pathways,mmu04070:Phosphatidylinositol signaling system, SM00128:IPPc,SM01165:SM01165, Complete proteome,Cytoplasm,Endocytosis,Hydrolase,Methylation,Phosphoprotein,Proteomics identification,Reference proteome,Repeat,RNA-binding, chain:Synaptojanin-1,compositionally biased region:Pro-rich,domain:RRM,domain:SAC,modified residue, Q3T0C9 synaptojanin 2 binding protein(SYNJ2BP) Bos taurus GO:0001937~negative regulation of endothelial cell proliferation,GO:0002092~positive regulation of receptor internalization,GO:0006605~protein targeting,GO:0006897~endocytosis,GO:0007266~Rho protein signal transduction,GO:0008593~regulation of Notch signaling pathway,GO:0010596~negative regulation of endothelial cell migration,GO:0016525~negative regulation of angiogenesis,GO:0032926~negative regulation of activin receptor signaling pathway,GO:0032927~positive regulation of activin receptor signaling pathway,GO:0070373~negative regulation of ERK1 and ERK2 cascade,GO:1903671~negative regulation of sprouting angiogenesis,GO:2000010~positive regulation of protein localization to cell surface, GO:0005739~mitochondrion,GO:0005741~mitochondrial outer membrane,GO:0009986~cell surface,GO:0016021~integral component of membrane,GO:0048471~perinuclear region of cytoplasm, IPR001478:PDZ domain, SM00228:PDZ, Complete proteome,Cytoplasm,Endocytosis,Membrane,Mitochondrion,Mitochondrion outer membrane,Reference proteome,Signal-anchor,Transmembrane,Transmembrane helix, chain:Synaptojanin-2-binding protein,domain:PDZ,topological domain:Cytoplasmic,topological domain:Mitochondrial intermembrane,transmembrane region, Q5EAR5 tRNA phosphotransferase 1(trpt1) Danio rerio GO:0006388~tRNA splicing, via endonucleolytic cleavage and ligation,GO:0008033~tRNA processing, GO:0000215~tRNA 2'-phosphotransferase activity,GO:0016740~transferase activity,GO:0016772~transferase activity, transferring phosphorus-containing groups, IPR002745:Phosphotransferase KptA/Tpt1, Complete proteome,NAD,Reference proteome,Transferase,tRNA processing, chain:tRNA 2'-phosphotransferase 1, Q6NUS6 tectonic family member 3(TCTN3) Homo sapiens GO:0006915~apoptotic process,GO:0007224~smoothened signaling pathway,GO:0060271~cilium morphogenesis, GO:0016021~integral component of membrane,GO:0060170~ciliary membrane,GO:0070062~extracellular exosome, IPR011677:Domain of unknown function DUF1619, 258860~Orofaciodigital syndrome IV,614815~Joubert syndrome 18, Alternative splicing,Apoptosis,Ciliopathy,Cilium biogenesis/degradation,Complete proteome,Disease mutation,Glycoprotein,Joubert syndrome,Membrane,Proteomics identification,Reference proteome,Signal,Transmembrane,Transmembrane helix, chain:Tectonic-3,compositionally biased region:Cys-rich,glycosylation site:N-linked (GlcNAc...),sequence conflict,signal peptide,splice variant,topological domain:Cytoplasmic,topological domain:Extracellular,transmembrane region, Q4R9E0 tectonic family member 3(TCTN3) Macaca fascicularis GO:0006915~apoptotic process,GO:0007224~smoothened signaling pathway,GO:0060271~cilium morphogenesis, GO:0016021~integral component of membrane, IPR011677:Domain of unknown function DUF1619, Apoptosis,Cilium biogenesis/degradation,Glycoprotein,Membrane,Signal,Transmembrane,Transmembrane helix, P37837 transaldolase 1(TALDO1) Homo sapiens GO:0005975~carbohydrate metabolic process,GO:0005999~xylulose biosynthetic process,GO:0006002~fructose 6-phosphate metabolic process,GO:0006098~pentose-phosphate shunt,GO:0009052~pentose-phosphate shunt, non-oxidative branch, GO:0005634~nucleus,GO:0005737~cytoplasm,GO:0005829~cytosol,GO:0043231~intracellular membrane-bounded organelle,GO:0070062~extracellular exosome, GO:0003824~catalytic activity,GO:0004801~sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity,GO:0005515~protein binding,GO:0048029~monosaccharide binding, IPR001585:Transaldolase,IPR004730:Transaldolase type 1,IPR013785:Aldolase-type TIM barrel,IPR018225:Transaldolase, active site, hsa00030:Pentose phosphate pathway,hsa01100:Metabolic pathways,hsa01130:Biosynthesis of antibiotics,hsa01200:Carbon metabolism,hsa01230:Biosynthesis of amino acids, 606003~Transaldolase deficiency, 3D-structure,Acetylation,Complete proteome,Cytoplasm,Disease mutation,Pentose shunt,Phosphoprotein,Proteomics identification,Reference proteome,Schiff base,Transferase, chain:Transaldolase,helix,modified residue,sequence variant,strand,turn, F7H9X2 tripartite motif containing 2(TRIM2) Callithrix jacchus GO:0043523~regulation of neuron apoptotic process, GO:0005622~intracellular,GO:0005737~cytoplasm, GO:0004842~ubiquitin-protein transferase activity,GO:0008270~zinc ion binding,GO:0016874~ligase activity, IPR000315:Zinc finger, B-box,IPR001258:NHL repeat,IPR001298:Filamin/ABP280 repeat,IPR001841:Zinc finger, RING-type,IPR003649:B-box, C-terminal,IPR011042:Six-bladed beta-propeller, TolB-like,IPR013017:NHL repeat, subgroup,IPR013083:Zinc finger, RING/FYVE/PHD-type,IPR013783:Immunoglobulin-like fold,IPR014756:Immunoglobulin E-set,IPR017868:Filamin/ABP280 repeat-like,IPR017907:Zinc finger, RING-type, conserved site,IPR027370:RING-type zinc-finger, LisH dimerisation motif, SM00184:RING,SM00336:BBOX,SM00502:BBC,SM00557:IG_FLMN, Complete proteome,Cytoplasm,Ligase,Metal-binding,Phosphoprotein,Reference proteome,Repeat,Ubl conjugation,Ubl conjugation pathway,Zinc,Zinc-finger, D2GXS7 tripartite motif containing 2(TRIM2) Ailuropoda melanoleuca GO:0043523~regulation of neuron apoptotic process, GO:0005737~cytoplasm, GO:0004842~ubiquitin-protein transferase activity,GO:0008270~zinc ion binding,GO:0016874~ligase activity, IPR000315:Zinc finger, B-box,IPR001258:NHL repeat,IPR001298:Filamin/ABP280 repeat,IPR001841:Zinc finger, RING-type,IPR003649:B-box, C-terminal,IPR011042:Six-bladed beta-propeller, TolB-like,IPR013017:NHL repeat, subgroup,IPR013083:Zinc finger, RING/FYVE/PHD-type,IPR013783:Immunoglobulin-like fold,IPR014756:Immunoglobulin E-set,IPR017868:Filamin/ABP280 repeat-like,IPR017907:Zinc finger, RING-type, conserved site,IPR027370:RING-type zinc-finger, LisH dimerisation motif, SM00184:RING,SM00336:BBOX,SM00502:BBC,SM00557:IG_FLMN, Complete proteome,Cytoplasm,Ligase,Metal-binding,Phosphoprotein,Reference proteome,Repeat,Ubl conjugation,Ubl conjugation pathway,Zinc,Zinc-finger, O75382 tripartite motif containing 3(TRIM3) Homo sapiens GO:0007399~nervous system development,GO:0015031~protein transport,GO:0016567~protein ubiquitination, GO:0005622~intracellular,GO:0005737~cytoplasm,GO:0005769~early endosome,GO:0005794~Golgi apparatus,GO:0030425~dendrite, GO:0005515~protein binding,GO:0008022~protein C-terminus binding,GO:0008270~zinc ion binding,GO:0061630~ubiquitin protein ligase activity, IPR000315:Zinc finger, B-box,IPR001258:NHL repeat,IPR001298:Filamin/ABP280 repeat,IPR001841:Zinc finger, RING-type,IPR003649:B-box, C-terminal,IPR011042:Six-bladed beta-propeller, TolB-like,IPR013017:NHL repeat, subgroup,IPR013083:Zinc finger, RING/FYVE/PHD-type,IPR013783:Immunoglobulin-like fold,IPR014756:Immunoglobulin E-set,IPR017868:Filamin/ABP280 repeat-like,IPR017907:Zinc finger, RING-type, conserved site,IPR027370:RING-type zinc-finger, LisH dimerisation motif, SM00184:RING,SM00336:BBOX,SM00502:BBC,SM00557:IG_FLMN, Acetylation,Alternative splicing,Cell projection,Coiled coil,Complete proteome,Cytoplasm,Endosome,Golgi apparatus,Metal-binding,Phosphoprotein,Polymorphism,Protein transport,Proteomics identification,Reference proteome,Repeat,Signal,Transport,Zinc,Zinc-finger, chain:Tripartite motif-containing protein 3,modified residue,repeat:Filamin,repeat:NHL 1,repeat:NHL 2,repeat:NHL 3,repeat:NHL 4,repeat:NHL 5,repeat:NHL 6,sequence conflict,sequence variant,splice variant,zinc finger region:B box-type,zinc finger region:RING-type, Q9BTW9 tubulin folding cofactor D(TBCD) Homo sapiens Posttranslational modification, protein turnover, chaperones / Cytoskeleton, GO:0006457~protein folding,GO:0007021~tubulin complex assembly,GO:0007023~post-chaperonin tubulin folding pathway,GO:0010812~negative regulation of cell-substrate adhesion,GO:0031115~negative regulation of microtubule polymerization,GO:0034333~adherens junction assembly,GO:0043547~positive regulation of GTPase activity,GO:0070830~bicellular tight junction assembly, GO:0005737~cytoplasm,GO:0005874~microtubule,GO:0005912~adherens junction,GO:0005923~bicellular tight junction,GO:0016328~lateral plasma membrane, GO:0005096~GTPase activator activity,GO:0005515~protein binding,GO:0048487~beta-tubulin binding,GO:0051087~chaperone binding, IPR011989:Armadillo-like helical,IPR016024:Armadillo-type fold,IPR022577:Tubulin-specific chaperone D, C-terminal, Alternative splicing,Cell junction,Cell membrane,Chaperone,Complete proteome,Cytoplasm,GTPase activation,Membrane,Polymorphism,Proteomics identification,Reference proteome,Repeat,Tight junction, chain:Tubulin-specific chaperone D,repeat:HEAT 1,repeat:HEAT 2,repeat:HEAT 3,sequence conflict,sequence variant,splice variant, Q62769 unc-13 homolog B(Unc13b) Rattus norvegicus GO:0007268~chemical synaptic transmission,GO:0007528~neuromuscular junction development,GO:0010808~positive regulation of synaptic vesicle priming,GO:0016081~synaptic vesicle docking,GO:0016082~synaptic vesicle priming,GO:0031914~negative regulation of synaptic plasticity,GO:0035249~synaptic transmission, glutamatergic,GO:0035556~intracellular signal transduction,GO:0045921~positive regulation of exocytosis,GO:0048172~regulation of short-term neuronal synaptic plasticity,GO:0050714~positive regulation of protein secretion,GO:0060384~innervation,GO:0061669~spontaneous neurotransmitter secretion,GO:0071333~cellular response to glucose stimulus,GO:0090382~phagosome maturation,GO:0097151~positive regulation of inhibitory postsynaptic potential,GO:1900426~positive regulation of defense response to bacterium, GO:0005622~intracellular,GO:0005737~cytoplasm,GO:0005794~Golgi apparatus,GO:0005829~cytosol,GO:0005886~plasma membrane,GO:0030054~cell junction,GO:0031594~neuromuscular junction,GO:0032009~early phagosome,GO:0043195~terminal bouton,GO:0044305~calyx of Held,GO:0048786~presynaptic active zone,GO:0097060~synaptic membrane,GO:0097470~ribbon synapse,GO:0098793~presynapse, GO:0005515~protein binding,GO:0005516~calmodulin binding,GO:0017075~syntaxin-1 binding,GO:0019905~syntaxin binding,GO:0019992~diacylglycerol binding,GO:0046872~metal ion binding, IPR000008:C2 calcium-dependent membrane targeting,IPR002219:Protein kinase C-like, phorbol ester/diacylglycerol binding,IPR010439:Calcium-dependent secretion activator,IPR014770:Munc13 homology 1,IPR014772:Mammalian uncoordinated homology 13, domain 2,IPR019558:Mammalian uncoordinated homology 13, subgroup, domain 2,IPR027080:Uncoordinated protein 13 (Unc-13), rno04721:Synaptic vesicle cycle, SM00109:C1,SM00239:C2,SM01145:SM01145, Alternative splicing,Cell junction,Cell membrane,Coiled coil,Complete proteome,Cytoplasm,Exocytosis,Membrane,Metal-binding,Phosphoprotein,Reference proteome,Repeat,Synapse,Zinc,Zinc-finger, chain:Protein unc-13 homolog B,domain:C2 1,domain:C2 2,domain:C2 3,domain:MHD1,domain:MHD2,modified residue,splice variant,zinc finger region:Phorbol-ester/DAG-type, Q80TY5 vacuolar protein sorting 13B(Vps13b) Mus musculus Intracellular trafficking and secretion, GO:0006810~transport,GO:0015031~protein transport, GO:0016021~integral component of membrane, IPR009543:Vacuolar protein sorting-associated protein 13 domain,IPR026854:Vacuolar protein sorting-associated protein 13A N-terminal domain, Complete proteome,Membrane,Phosphoprotein,Protein transport,Proteomics identification,Reference proteome,Signal,Transmembrane,Transmembrane helix,Transport, chain:Vacuolar protein sorting-associated protein 13B,modified residue,sequence conflict, Q9UJU3 zinc finger protein 112(ZNF112) Homo sapiens General function prediction only, GO:0006351~transcription, DNA-templated,GO:0006355~regulation of transcription, DNA-templated, GO:0005622~intracellular,GO:0005634~nucleus, GO:0003676~nucleic acid binding,GO:0003677~DNA binding,GO:0003700~transcription factor activity, sequence-specific DNA binding,GO:0046872~metal ion binding, IPR001909:Krueppel-associated box,IPR007087:Zinc finger, C2H2,IPR013087:Zinc finger C2H2-type/integrase DNA-binding domain,IPR015880:Zinc finger, C2H2-like, SM00349:KRAB,SM00355:ZnF_C2H2, Alternative splicing,Complete proteome,DNA-binding,Metal-binding,Nucleus,Polymorphism,Reference proteome,Repeat,Transcription,Transcription regulation,Zinc,Zinc-finger, chain:Zinc finger protein 112 homolog,domain:KRAB,sequence conflict,sequence variant,zinc finger region:C2H2-type 10,zinc finger region:C2H2-type 11,zinc finger region:C2H2-type 12,zinc finger region:C2H2-type 13,zinc finger region:C2H2-type 14,zinc finger region:C2H2-type 15,zinc finger region:C2H2-type 16,zinc finger region:C2H2-type 17,zinc finger region:C2H2-type 1; degenerate,zinc finger region:C2H2-type 2; degenerate,zinc finger region:C2H2-type 3; degenerate,zinc finger region:C2H2-type 4; degenerate,zinc finger region:C2H2-type 5,zinc finger region:C2H2-type 6,zinc finger region:C2H2-type 7,zinc finger region:C2H2-type 8,zinc finger region:C2H2-type 9,