**Annotation**
Of 153,982 sequences that remained after screening for putative non-eukaryote matches, 22,974 (15%) had similarity with proteins in the Swiss-Prot/Uniprot database. Corrresponding Biological Process Gene Ontology information was obtained for 19, 393 contigs.
Protein similarities were 12.2 % RNA metabolism, 11.5 % transport, 10.6 % protein metabolism and 18.9 % and 17.0 % with other metabolic and biological processes, respectively (Fig. )
**Figure .** *Panopea generosa* transcriptome gene ontology annotation.
**Fig.** *Panopea generosa* transcriptome gene ontology annotation without bacterial annotation but with reproduction annotation (extracted from other other biological processes).
In comparing the Panopea transcriptome with previously described gene sets two contigs were identifed as putatively sex-specific based on work in _Crassostrea gigas_. This incudes contig comp142444, analogous to Forkhead box protein L2 and comp137246 with homology to actin, cytoplasmic A3a and comp142462_c1_seq1 analogous to the sperm-associated antigen 6 (involved in sperm motility). $$$need to confirm not non-euk$$$. There were 173 contigs that corresponded to gene identified in _Crassostrea gigas_ to be differentially expressed through gametogenesis.
Fig. with Dheilly's ( Cluster Des.)
| Panopea_contig | evalue | Sigenae_id | Description | Cluster | Cluster Des. | Tissue-enriched expression | High expression | Adj p value |
|---------------------|-----------|------------|----------------------------------------------------------------------------------------------------------------------------------------|---------|--------------------|----------------------------|------------------------|-------------|
| comp142515_c0_seq2 | 0 | CU683354 | (sp:P18091) Alpha-actinin, sarcomeric OS=Drosophila melanogaster GN=Actn PE=2 SV=2 | 1 | Stage 0 | | Adductor muscle | 2.58E-07 |
| comp137246_c1_seq26 | 3.00E-64 | CU684679 | (sp:P00544) Tyrosine-protein kinase transforming protein Fgr OS=Feline sarcoma virus (strain Gardner-Rasheed) GN=V-FGR PE=3 SV=1 | 1 | Stage 0 | | #N/A | 3.61E-06 |
| comp116682_c1_seq2 | 1.00E-71 | EW778003 | (sp:P04412) Epidermal growth factor receptor OS=Drosophila melanogaster GN=Egfr PE=1 SV=3 | 1 | Stage 0 | | Adductor muscle | 4.05E-06 |
| comp143196_c0_seq1 | 1.00E-136 | CU996492 | (sp:P04040) Catalase OS=Homo sapiens GN=CAT PE=1 SV=3 | 1 | Stage 0 | | hemocytes | 4.41E-06 |
| comp124055_c0_seq3 | 6.00E-151 | CU686207 | (sp:P24733) Myosin heavy chain, striated muscle OS=Aequipecten irradians PE=1 SV=1 | 1 | Stage 0 | adductor muscle | Adductor muscle | 4.14E-07 |
| comp127090_c0_seq1 | 4.00E-80 | DW713853 | (sp:O08584) Krueppel-like factor 6 OS=Mus musculus GN=Klf6 PE=2 SV=3 | 1 | Stage 0 | | hemocytes | 4.20E-06 |
| comp141240_c0_seq5 | 5.00E-71 | FP010851 | (sp:A2APV2) Formin-like protein 2 OS=Mus musculus GN=Fmnl2 PE=2 SV=2 | 1 | Stage 0 | | Adductor muscle | 2.78E-06 |
| comp142437_c1_seq3 | 1.00E-70 | AM864624 | (sp:Q6GYQ0) Ral GTPase-activating protein alpha subunit 1 OS=Homo sapiens GN=RALGAPA1 PE=1 SV=1 | 1 | Stage 0 | | hemocytes | 4.43E-06 |
| comp142424_c2_seq1 | 2.00E-95 | CU995837 | (sp:Q14315) Filamin-C OS=Homo sapiens GN=FLNC PE=1 SV=3 | 2 | Mature Female only | | #N/A | 5.84E-06 |
| comp133082_c0_seq2 | 2.00E-117 | DV736298 | (sp:Q9PU85) Serine/threonine-protein kinase Pim-3 OS=Coturnix coturnix japonica GN=PIM3 PE=2 SV=1 | 2 | Mature Female only | | #N/A | 6.16E-06 |
| comp143573_c0_seq1 | 0 | EW778397 | (sp:P35224) Catenin beta OS=Urechis caupo PE=2 SV=1 | 2 | Mature Female only | female gonad | #N/A | 5.87E-07 |
| comp143196_c0_seq1 | 0 | EF687775 | (sp:Q9PWF7) Catalase OS=Rana rugosa GN=cat PE=2 SV=3 | 2 | Mature Female only | | #N/A | 1.05E-06 |
| comp140491_c1_seq2 | 1.00E-101 | AJ535669 | (sp:Q25410) Putative molluscan insulin-related peptide(s) receptor OS=Lymnaea stagnalis PE=2 SV=1 | 2 | Mature Female only | | #N/A | 2.46E-06 |
| comp142337_c2_seq1 | 3.00E-78 | AM862948 | (sp:Q6P1R4) tRNA-dihydrouridine synthase 1-like OS=Homo sapiens GN=DUS1L PE=1 SV=1 | 2 | Mature Female only | | #N/A | 2.00E-07 |
| comp144262_c1_seq8 | 2.00E-117 | AM863520 | (sp:Q5R416) Catenin alpha-2 OS=Pongo abelii GN=CTNNA2 PE=2 SV=3 | 3 | Female stage 2 | | #N/A | 1.52E-07 |
| comp136546_c0_seq2 | 2.00E-93 | AM868009 | (sp:Q8VBV4) F-box/WD repeat-containing protein 7 OS=Mus musculus GN=Fbxw7 PE=1 SV=1 | 3 | Female stage 2 | | #N/A | 1.87E-09 |
| comp140336_c1_seq1 | 5.00E-113 | AM867657 | (sp:Q9NXV2) BTB/POZ domain-containing protein KCTD5 OS=Homo sapiens GN=KCTD5 PE=1 SV=1 | 3 | Female stage 2 | female gonad | #N/A | 1.02E-06 |
| comp140253_c0_seq2 | 2.00E-64 | AM854424 | (sp:Q9CY50) Translocon-associated protein subunit alpha OS=Mus musculus GN=Ssr1 PE=1 SV=1 | 3 | Female stage 2 | | #N/A | 1.95E-07 |
| comp138450_c0_seq1 | 3.00E-119 | AM860854 | (sp:Q13415) Origin recognition complex subunit 1 OS=Homo sapiens GN=ORC1L PE=1 SV=2 | 3 | Female stage 2 | | #N/A | 4.89E-08 |
| comp140963_c2_seq2 | 5.00E-114 | AM857825 | (sp:Q09472) Histone acetyltransferase p300 OS=Homo sapiens GN=EP300 PE=1 SV=2 | 3 | Female stage 2 | | #N/A | 4.59E-06 |
| comp139776_c0_seq1 | 2.00E-94 | AM858464 | (sp:P49366) Deoxyhypusine synthase OS=Homo sapiens GN=DHPS PE=1 SV=1 | 3 | Female stage 2 | | #N/A | 4.38E-06 |
| comp143626_c0_seq1 | 8.00E-76 | CU994233 | (sp:Q9BYJ9) YTH domain family protein 1 OS=Homo sapiens GN=YTHDF1 PE=1 SV=1 | 3 | Female stage 2 | | #N/A | 5.81E-06 |
| comp138448_c0_seq6 | 6.00E-103 | AM858915 | (sp:O75925) E3 SUMO-protein ligase PIAS1 OS=Homo sapiens GN=PIAS1 PE=1 SV=2 | 3 | Female stage 2 | | #N/A | 5.77E-06 |
| comp137128_c0_seq1 | 4.00E-109 | AM861629 | (sp:Q60809) CCR4-NOT transcription complex subunit 7 OS=Mus musculus GN=Cnot7 PE=1 SV=1 | 3 | Female stage 2 | female gonad | #N/A | 1.11E-08 |
| comp123995_c0_seq1 | 4.00E-96 | AM867308 | (sp:Q5ZKN1) Cell division protein kinase 9 OS=Gallus gallus GN=CDK9 PE=2 SV=1 | 3 | Female stage 2 | | #N/A | 6.03E-06 |
| comp142670_c2_seq1 | 4.00E-94 | AM861996 | (sp:B2GUV7) Eukaryotic translation initiation factor 5B OS=Rattus norvegicus GN=Eif5b PE=1 SV=1 | 3 | Female stage 2 | | #N/A | 5.91E-06 |
| comp139276_c1_seq1 | 2.00E-180 | AY551096 | (sp:Q4R502) Isocitrate dehydrogenase [NADP], mitochondrial OS=Macaca fascicularis GN=IDH2 PE=2 SV=1 | 4 | Female early stage | | #N/A | 3.42E-08 |
| comp142444_c0_seq2 | 9.00E-63 | AM860211 | (sp:Q6VFT5) Forkhead box protein L2 OS=Oryctolagus cuniculus GN=FOXL2 PE=4 SV=1 | 4 | Female early stage | female gonad | #N/A | 5.03E-07 |
| comp142747_c0_seq1 | 0 | AM860498 | (sp:Q4R6T7) IQ and ubiquitin-like domain-containing protein OS=Macaca fascicularis GN=IQUB PE=2 SV=2 | 4 | Female early stage | female gonad | #N/A | 1.49E-09 |
| comp144028_c0_seq3 | 4.00E-98 | CU989217 | (sp:Q499P8) UPF0420 protein C16orf58 homolog OS=Rattus norvegicus PE=2 SV=1 | 4 | Female early stage | female gonad | #N/A | 0 |
| comp138731_c0_seq1 | 3.00E-67 | AM855680 | (sp:Q13889) General transcription factor IIH subunit 3 OS=Homo sapiens GN=GTF2H3 PE=1 SV=2 | 4 | Female early stage | female gonad | #N/A | 4.22E-06 |
| comp141098_c0_seq4 | 6.00E-99 | AM862974 | (sp:P56839) Phosphoenolpyruvate phosphomutase OS=Mytilus edulis PE=1 SV=3 | 4 | Female early stage | | #N/A | 3.78E-07 |
| comp142230_c1_seq2 | 7.00E-74 | AJ563467 | (sp:Q24800) Severin OS=Echinococcus granulosus GN=AG8 PE=2 SV=3 | 4 | Female early stage | | #N/A | 3.00E-09 |
| comp123534_c0_seq1 | 5.00E-88 | CU686151 | (sp:Q5RFA3) Alanine--glyoxylate aminotransferase 2, mitochondrial OS=Pongo abelii GN=AGXT2 PE=2 SV=1 | 4 | Female early stage | | #N/A | 4.62E-06 |
| comp143076_c0_seq6 | 2.00E-107 | FP003042 | (sp:P35611) Alpha-adducin OS=Homo sapiens GN=ADD1 PE=1 SV=2 | 4 | Female early stage | female gonad | #N/A | 1.01E-06 |
| comp141720_c0_seq4 | 7.00E-172 | BQ427315 | (sp:P80467) Alcohol dehydrogenase class-3 OS=Uromastyx hardwickii PE=1 SV=1 | 4 | Female early stage | | #N/A | 6.19E-06 |
| comp135897_c0_seq2 | 1.00E-91 | AM866953 | (sp:A4IF62) DNA-directed RNA polymerase III subunit RPC1 OS=Bos taurus GN=POLR3A PE=2 SV=1 | 4 | Female early stage | | #N/A | 6.20E-06 |
| comp142890_c1_seq1 | 1.00E-96 | EE677697 | (sp:Q7QC84) Probable methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial OS=Anopheles gambiae GN=AGAP002499 PE=3 SV=2 | 4 | Female early stage | | #N/A | 1.29E-06 |
| comp140153_c0_seq2 | 3.00E-80 | AM855747 | (sp:Q5R4R4) Protein LSM14 homolog A OS=Pongo abelii GN=LSM14A PE=2 SV=1 | 4 | Female early stage | | #N/A | 6.87E-10 |
| comp117801_c0_seq1 | 3.00E-80 | CU987737 | (sp:Q3SZR5) UPF0573 protein C2orf70 homolog OS=Bos taurus PE=2 SV=1 | 5 | Mature Male only | | Labial palps and gills | 8.71E-07 |
| comp137961_c2_seq3 | 2.00E-159 | AM855102 | (sp:Q9DAK2) Parkin coregulated gene protein homolog OS=Mus musculus GN=Pacrg PE=2 SV=1 | 5 | Mature Male only | | Labial palps and gills | 4.37E-06 |
| comp136738_c2_seq4 | 6.00E-87 | AM868587 | (sp:P14100) Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A OS=Bos taurus GN=PDE1A PE=1 SV=3 | 5 | Mature Male only | male gonad | #N/A | 8.26E-13 |
| comp142462_c1_seq1 | 2.00E-93 | AM860311 | (sp:Q9JLI7) Sperm-associated antigen 6 OS=Mus musculus GN=Spag6 PE=1 SV=1 | 5 | Mature Male only | | Labial palps and gills | 2.57E-06 |
| comp142462_c0_seq1 | 2.00E-136 | CU684841 | (sp:Q9JLI7) Sperm-associated antigen 6 OS=Mus musculus GN=Spag6 PE=1 SV=1 | 5 | Mature Male only | | Labial palps and gills | 4.60E-06 |
| comp134276_c0_seq1 | 0 | AM855501 | (sp:Q26630) 33 kDa inner dynein arm light chain, axonemal OS=Strongylocentrotus purpuratus PE=1 SV=1 | 5 | Mature Male only | | Labial palps and gills | 4.86E-07 |
| comp108487_c0_seq1 | 6.00E-71 | ES789247 | (sp:Q6SP97) Enkurin OS=Mus musculus GN=Enkur PE=1 SV=1 | 5 | Mature Male only | | Labial palps and gills | 4.92E-06 |
| comp115977_c0_seq1 | 9.00E-97 | AM866946 | (sp:Q5PPV3) MORN repeat-containing protein 3 OS=Xenopus laevis GN=morn3 PE=2 SV=1 | 5 | Mature Male only | male gonad | Labial palps and gills | 5.39E-06 |
| comp94584_c0_seq1 | 1.00E-63 | ES789955 | (sp:A6NL82) Protein FAM183A OS=Homo sapiens GN=FAM183A PE=2 SV=2 | 5 | Mature Male only | | Labial palps and gills | 2.43E-07 |
| comp140956_c1_seq6 | 2.00E-97 | AM860858 | (sp:Q3UFY4) Radial spoke head protein 3 homolog A OS=Mus musculus GN=Rsph3a PE=2 SV=1 | 5 | Mature Male only | | Labial palps and gills | 1.80E-08 |
| comp117922_c0_seq1 | 7.00E-67 | AM859590 | (sp:Q9UHP6) Rhabdoid tumor deletion region protein 1 OS=Homo sapiens GN=RTDR1 PE=2 SV=1 | 5 | Mature Male only | | Labial palps and gills | 3.00E-07 |
| comp142747_c0_seq1 | 1.00E-173 | CU998233 | (sp:Q4R6T7) IQ and ubiquitin-like domain-containing protein OS=Macaca fascicularis GN=IQUB PE=2 SV=2 | 5 | Mature Male only | | Labial palps and gills | 2.88E-06 |
| comp141774_c1_seq1 | 3.00E-154 | AM857935 | (sp:Q66IS6) Bardet-Biedl syndrome 5 protein homolog OS=Xenopus laevis GN=bbs5 PE=2 SV=1 | 5 | Mature Male only | male gonad | Labial palps and gills | 8.98E-07 |
| comp135381_c0_seq1 | 2.00E-173 | ES789943 | (sp:Q80Y75) DnaJ homolog subfamily B member 13 OS=Mus musculus GN=Dnajb13 PE=2 SV=1 | 5 | Mature Male only | | Labial palps and gills | 6.11E-07 |
| comp137961_c2_seq3 | 4.00E-155 | CU992930 | (sp:Q9DAK2) Parkin coregulated gene protein homolog OS=Mus musculus GN=Pacrg PE=2 SV=1 | 5 | Mature Male only | | Labial palps and gills | 6.13E-07 |
| comp133634_c0_seq1 | 5.00E-104 | CU682555 | (sp:Q4R7Y8) Uncharacterized protein C14orf45 homolog OS=Macaca fascicularis GN=QtsA-11302 PE=2 SV=2 | 5 | Mature Male only | | Labial palps and gills | 9.80E-07 |
| comp28306_c0_seq1 | 3.00E-91 | AM861826 | (sp:Q4V7T8) Ropporin-1-like protein OS=Xenopus laevis GN=ropn1l PE=2 SV=1 | 5 | Mature Male only | | Labial palps and gills | 2.30E-08 |
| comp144411_c0_seq3 | 5.00E-89 | AM859337 | (sp:P0C5J2) B9 domain-containing protein 1 OS=Rattus norvegicus GN=B9d1 PE=2 SV=1 | 5 | Mature Male only | | #N/A | 6.23E-07 |
| comp127584_c0_seq1 | 7.00E-151 | AM853323 | (sp:O15990) Arginine kinase OS=Liolophura japonica PE=2 SV=1 | 5 | Mature Male only | male gonad | #N/A | 5.35E-06 |
| comp143382_c0_seq4 | 1.00E-107 | AM866114 | (sp:Q8IWZ6) Bardet-Biedl syndrome 7 protein OS=Homo sapiens GN=BBS7 PE=1 SV=2 | 5 | Mature Male only | | Labial palps and gills | 2.46E-06 |
| comp125539_c0_seq1 | 5.00E-120 | DV736572 | (sp:P56597) Nucleoside diphosphate kinase homolog 5 OS=Homo sapiens GN=NME5 PE=1 SV=1 | 5 | Mature Male only | | Labial palps and gills | 2.23E-09 |
| comp141715_c0_seq3 | 3.00E-67 | AM854208 | (sp:Q28G94) Dynein light chain 1, axonemal OS=Xenopus tropicalis GN=dnal1 PE=2 SV=1 | 5 | Mature Male only | | Labial palps and gills | 1.90E-06 |
| comp130790_c0_seq2 | 7.00E-130 | AM862765 | (sp:Q9Z1K5) Protein ariadne-1 homolog OS=Mus musculus GN=Arih1 PE=2 SV=3 | 5 | Mature Male only | male gonad | #N/A | 3.95E-10 |
| comp130334_c1_seq1 | 2.00E-87 | AM866620 | (sp:Q8CCB4) Vacuolar protein sorting-associated protein 53 homolog OS=Mus musculus GN=Vps53 PE=2 SV=1 | 5 | Mature Male only | male gonad | Visceral ganglion | 6.55E-08 |
| comp143876_c0_seq7 | 7.00E-86 | BQ426960 | (sp:A1A5Q4) UPF0704 protein C6orf165 homolog OS=Rattus norvegicus PE=2 SV=1 | 5 | Mature Male only | | Labial palps and gills | 8.13E-08 |
| comp138578_c1_seq1 | 1.00E-105 | CU993384 | (sp:Q5JVL4) EF-hand domain-containing protein 1 OS=Homo sapiens GN=EFHC1 PE=1 SV=1 | 5 | Mature Male only | | Labial palps and gills | 1.92E-06 |
| comp138578_c0_seq1 | 3.00E-96 | ES789239 | (sp:Q9D9T8) EF-hand domain-containing protein 1 OS=Mus musculus GN=Efhc1 PE=1 SV=1 | 5 | Mature Male only | | Labial palps and gills | 1.56E-06 |
| comp141641_c0_seq2 | 6.00E-78 | CU685202 | (sp:Q5T655) Coiled-coil domain-containing protein 147 OS=Homo sapiens GN=CCDC147 PE=2 SV=1 | 5 | Mature Male only | | Labial palps and gills | 2.50E-07 |
| comp137723_c0_seq1 | 1.00E-91 | AM856886 | (sp:Q0VFN8) Uncharacterized protein C9orf117 homolog OS=Xenopus tropicalis PE=2 SV=1 | 5 | Mature Male only | | Labial palps and gills | 1.65E-07 |
| comp142619_c0_seq8 | 3.00E-81 | CU994336 | (sp:Q9BZ19) Ankyrin repeat domain-containing protein 60 OS=Homo sapiens GN=ANKRD60 PE=2 SV=3 | 5 | Mature Male only | | Labial palps and gills | 1.84E-07 |
| comp50630_c0_seq1 | 1.00E-141 | CU983935 | (sp:Q567I9) Cytochrome b5 domain-containing protein 1 OS=Danio rerio GN=cyb5d1 PE=2 SV=1 | 5 | Mature Male only | | Labial palps and gills | 5.40E-08 |
| comp59400_c0_seq1 | 2.00E-66 | AM864903 | (sp:Q96M60) Uncharacterized protein C15orf33 OS=Homo sapiens GN=C15orf33 PE=2 SV=2 | 5 | Mature Male only | male gonad | Labial palps and gills | 5.54E-06 |
| comp144123_c0_seq3 | 5.00E-77 | EE677599 | (sp:O43805) Sjoegren syndrome nuclear autoantigen 1 OS=Homo sapiens GN=SSNA1 PE=1 SV=2 | 5 | Mature Male only | | #N/A | 5.91E-06 |
| comp111825_c0_seq1 | 5.00E-100 | CU987413 | (sp:Q28FE4) MORN repeat-containing protein 5 OS=Xenopus tropicalis GN=morn5 PE=2 SV=1 | 5 | Mature Male only | male gonad | Labial palps and gills | 4.03E-09 |
| comp143022_c0_seq8 | 1.00E-94 | AM864669 | (sp:Q6NZQ0) Coiled-coil domain-containing protein C16orf93 homolog OS=Mus musculus GN=Gm166 PE=2 SV=2 | 5 | Mature Male only | | Labial palps and gills | 2.05E-07 |
| comp131335_c0_seq1 | 1.00E-128 | AM857430 | (sp:Q0VC09) RIB43A-like with coiled-coils protein 1 OS=Bos taurus GN=RIBC1 PE=2 SV=1 | 5 | Mature Male only | | Labial palps and gills | 5.50E-06 |
| comp142462_c0_seq1 | 9.00E-138 | CU990254 | (sp:Q9JLI7) Sperm-associated antigen 6 OS=Mus musculus GN=Spag6 PE=1 SV=1 | 5 | Mature Male only | | Labial palps and gills | 1.46E-06 |
| comp140104_c0_seq1 | 4.00E-108 | AM858229 | (sp:Q4R642) T-complex-associated testis-expressed protein 1 OS=Macaca fascicularis GN=TCTE1 PE=2 SV=1 | 5 | Mature Male only | | Labial palps and gills | 1.66E-06 |
| comp141939_c0_seq2 | 0 | AM857837 | (sp:A7MBF6) Uncharacterized protein C1orf228 homolog OS=Bos taurus PE=2 SV=1 | 5 | Mature Male only | | Labial palps and gills | 4.65E-07 |
| comp140126_c0_seq2 | 1.00E-139 | AM869290 | (sp:P12370) cAMP-dependent protein kinase catalytic subunit OS=Drosophila melanogaster GN=Pka-C1 PE=1 SV=3 | 6 | Male 1-3 increase | | #N/A | 1.01E-07 |
| comp122083_c0_seq1 | 1.00E-76 | AM854428 | (sp:P62870) Transcription elongation factor B polypeptide 2 OS=Rattus norvegicus GN=Tceb2 PE=1 SV=1 | 6 | Male 1-3 increase | | #N/A | 3.35E-09 |
| comp123774_c0_seq1 | 0 | AJ431728 | (sp:P41383) Tubulin alpha-2/alpha-4 chain OS=Patella vulgata GN=TUB2 PE=2 SV=1 | 6 | Male 1-3 increase | male gonad | #N/A | 4.67E-07 |
| comp131711_c0_seq2 | 4.00E-127 | DW713885 | (sp:Q95NR9) Calmodulin OS=Metridium senile PE=1 SV=3 | 6 | Male 1-3 increase | | #N/A | 4.10E-09 |
| comp130892_c0_seq2 | 3.00E-65 | FP008556 | (sp:Q3SXZ7) Probable tubulin polyglutamylase TTLL9 OS=Homo sapiens GN=TTLL9 PE=2 SV=3 | 6 | Male 1-3 increase | | Labial palps and gills | 9.98E-07 |
| comp137246_c1_seq24 | 7.00E-117 | CF369133 | (sp:Q25010) Actin, cytoplasmic A3a OS=Helicoverpa armigera GN=actA3a PE=2 SV=1 | 6 | Male 1-3 increase | | #N/A | 7.24E-09 |
| comp140005_c4_seq4 | 1.00E-90 | AM858990 | (sp:O02485) Uncharacterized protein ZK1073.1 OS=Caenorhabditis elegans GN=ZK1073.1 PE=2 SV=1 | 6 | Male 1-3 increase | | #N/A | 6.25E-07 |
| comp142657_c2_seq1 | 2.00E-71 | AM859447 | (sp:Q9UPY8) Microtubule-associated protein RP/EB family member 3 OS=Homo sapiens GN=MAPRE3 PE=1 SV=1 | 6 | Male 1-3 increase | | #N/A | 5.16E-06 |
| comp143518_c1_seq3 | 4.00E-82 | AM863560 | (sp:Q7ZVC2) Clusterin-associated protein 1 homolog OS=Danio rerio GN=cluap1 PE=2 SV=2 | 7 | Males and Females | | #N/A | 9.85E-07 |
| comp143850_c0_seq23 | 2.00E-131 | CU995306 | (sp:P48380) Transcription factor RFX3 OS=Homo sapiens GN=RFX3 PE=2 SV=2 | 7 | Males and Females | | #N/A | 1.63E-07 |
| comp141725_c0_seq1 | 2.00E-69 | CU682645 | (sp:P67963) Casein kinase I isoform alpha OS=Xenopus laevis GN=csnk1a1 PE=2 SV=1 | 7 | Males and Females | | #N/A | 1.89E-06 |
| comp141064_c0_seq10 | 8.00E-69 | AM865392 | (sp:O14578) Citron Rho-interacting kinase OS=Homo sapiens GN=CIT PE=1 SV=2 | 7 | Males and Females | | #N/A | 2.35E-07 |
| comp139568_c4_seq3 | 8.00E-107 | AM857512 | (sp:P54279) Mismatch repair endonuclease PMS2 OS=Mus musculus GN=Pms2 PE=1 SV=1 | 7 | Males and Females | | #N/A | 6.15E-06 |
| comp123636_c0_seq1 | 8.00E-61 | CX069346 | (sp:Q6QLW4) Cytochrome c OS=Pectinaria gouldii PE=3 SV=1 | 7 | Males and Females | | #N/A | 4.97E-08 |
| comp134267_c0_seq5 | 3.00E-122 | AM864416 | (sp:Q92630) Dual specificity tyrosine-phosphorylation-regulated kinase 2 OS=Homo sapiens GN=DYRK2 PE=1 SV=3 | 7 | Males and Females | | #N/A | 1.14E-08 |
| comp110047_c0_seq2 | 1.00E-90 | FP003003 | (sp:Q922R1) UPF0183 protein C16orf70 homolog OS=Mus musculus PE=2 SV=1 | 7 | Males and Females | | #N/A | 1.49E-06 |
| comp137292_c0_seq2 | 1.00E-107 | AM861293 | (sp:Q96GG9) DCN1-like protein 1 OS=Homo sapiens GN=DCUN1D1 PE=1 SV=1 | 7 | Males and Females | | #N/A | 5.91E-06 |
| comp133345_c1_seq2 | 7.00E-64 | AM859011 | (sp:Q5VVX9) Ubiquitin-conjugating enzyme E2 U OS=Homo sapiens GN=UBE2U PE=1 SV=1 | 7 | Males and Females | | #N/A | 1.67E-07 |
| comp139567_c0_seq6 | 4.00E-155 | AM868574 | (sp:P51892) DNA ligase 1 OS=Xenopus laevis GN=lig1 PE=2 SV=1 | 7 | Males and Females | | #N/A | 5.92E-09 |
| comp132821_c0_seq1 | 4.00E-86 | AM856856 | (sp:Q8CFP6) DnaJ homolog subfamily C member 27 OS=Mus musculus GN=Dnajc27 PE=2 SV=1 | 7 | Males and Females | | #N/A | 2.40E-06 |
| comp144394_c0_seq3 | 4.00E-66 | ES789731 | (sp:Q13099) Intraflagellar transport protein 88 homolog OS=Homo sapiens GN=IFT88 PE=1 SV=2 | 7 | Males and Females | | #N/A | 6.02E-08 |
| comp142811_c0_seq2 | 1.00E-109 | BQ427333 | (sp:Q9BPU9) B9 domain-containing protein 2 OS=Homo sapiens GN=B9D2 PE=2 SV=2 | 7 | Males and Females | | #N/A | 4.10E-06 |
| comp144511_c0_seq9 | 2.00E-116 | AM237648 | (sp:Q801E2) Actin-binding protein anillin OS=Xenopus laevis GN=anln PE=1 SV=1 | 7 | Males and Females | | #N/A | 1.26E-09 |
| comp129985_c0_seq1 | 2.00E-103 | AM861092 | (sp:O75800) Zinc finger MYND domain-containing protein 10 OS=Homo sapiens GN=ZMYND10 PE=1 SV=2 | 7 | Males and Females | | #N/A | 1.68E-07 |
| comp143973_c1_seq2 | 5.00E-109 | AM859992 | (sp:Q9DE46) DNA polymerase alpha catalytic subunit OS=Xenopus laevis GN=pola1 PE=2 SV=1 | 7 | Males and Females | | #N/A | 2.13E-07 |
| comp140707_c3_seq1 | 3.00E-122 | AM862862 | (sp:Q7YR39) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Pan troglodytes GN=DHX16 PE=3 SV=1 | 7 | Males and Females | | #N/A | 6.21E-06 |
| comp112669_c1_seq1 | 7.00E-63 | CU995701 | (sp:Q8TAM2) Tetratricopeptide repeat protein 8 OS=Homo sapiens GN=TTC8 PE=1 SV=1 | 7 | Males and Females | | #N/A | 5.96E-06 |
| comp138574_c1_seq1 | 9.00E-116 | AM864177 | (sp:Q68FX0) Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial OS=Rattus norvegicus GN=Idh3B PE=2 SV=1 | 8 | Males and Females | male gonad | #N/A | 2.95E-06 |
| comp136486_c0_seq2 | 2.00E-80 | AM863722 | (sp:Q3MHN0) Proteasome subunit beta type-6 OS=Bos taurus GN=PSMB6 PE=1 SV=1 | 8 | Males and Females | | #N/A | 1.10E-06 |
| comp130260_c0_seq1 | 5.00E-96 | CU991591 | (sp:P70040) Flap endonuclease 1-A OS=Xenopus laevis GN=fen1-A PE=1 SV=1 | 8 | Males and Females | | #N/A | 3.54E-08 |
| comp143568_c0_seq2 | 9.00E-163 | CU991150 | (sp:P49739) Maternal DNA replication licensing factor mcm3 OS=Xenopus laevis GN=mmcm3 PE=1 SV=2 | 8 | Males and Females | | #N/A | 1.17E-07 |
| comp131711_c0_seq3 | 4.00E-148 | CD526833 | (sp:Q8STF0) Calmodulin OS=Strongylocentrotus intermedius PE=2 SV=3 | 8 | Males and Females | | #N/A | 3.85E-07 |
| comp122280_c0_seq1 | 2.00E-71 | AM864414 | (sp:O73672) Proteasome subunit alpha type-2 OS=Carassius auratus GN=psma2 PE=2 SV=3 | 8 | Males and Females | | #N/A | 5.88E-07 |
| comp142222_c0_seq2 | 1.00E-88 | AM859623 | (sp:Q99J62) Replication factor C subunit 4 OS=Mus musculus GN=Rfc4 PE=1 SV=1 | 8 | Males and Females | | #N/A | 1.75E-07 |
| comp134749_c0_seq1 | 7.00E-151 | BQ426386 | (sp:Q9PTW9) Proteasome subunit alpha type-7 OS=Carassius auratus GN=psma7 PE=2 SV=1 | 8 | Males and Females | | #N/A | 8.88E-08 |
| comp142431_c0_seq2 | 7.00E-124 | CU986637 | (sp:P62489) DNA-directed RNA polymerase II subunit RPB7 OS=Rattus norvegicus GN=Polr2g PE=2 SV=1 | 8 | Males and Females | | #N/A | 2.38E-08 |
| comp142594_c0_seq1 | 1.00E-114 | AM861427 | (sp:P20664) DNA primase small subunit OS=Mus musculus GN=Prim1 PE=1 SV=1 | 8 | Males and Females | | #N/A | 1.02E-06 |
| comp123874_c0_seq2 | 2.00E-69 | FP005816 | (sp:Q9CY94) DNA replication complex GINS protein PSF3 OS=Mus musculus GN=Gins3 PE=2 SV=1 | 8 | Males and Females | | #N/A | 1.19E-06 |
| comp143216_c1_seq8 | 2.00E-67 | AM864974 | (sp:Q556Y9) Mitotic spindle assembly checkpoint protein MAD2A OS=Dictyostelium discoideum GN=mad2l1-1 PE=3 SV=1 | 8 | Males and Females | | #N/A | 1.56E-08 |
| comp138574_c1_seq1 | 8.00E-88 | CU989074 | (sp:Q68FX0) Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial OS=Rattus norvegicus GN=Idh3B PE=2 SV=1 | 8 | Males and Females | male gonad | #N/A | 2.16E-06 |
| comp139946_c0_seq6 | 5.00E-113 | AM861838 | (sp:P35250) Replication factor C subunit 2 OS=Homo sapiens GN=RFC2 PE=1 SV=3 | 8 | Males and Females | | #N/A | 4.32E-07 |
| comp124268_c0_seq1 | 7.00E-120 | AM864705 | (sp:P70195) Proteasome subunit beta type-7 OS=Mus musculus GN=Psmb7 PE=1 SV=1 | 8 | Males and Females | | #N/A | 1.83E-07 |
| comp50528_c0_seq1 | 1.00E-64 | AM858935 | (sp:Q0MQI7) NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial OS=Pongo pygmaeus GN=NDUFV2 PE=2 SV=1 | 8 | Males and Females | | #N/A | 7.97E-07 |
| comp143707_c0_seq1 | 8.00E-80 | AM856942 | (sp:Q7T0M6) Histone chaperone asf1-B OS=Xenopus laevis GN=asf1-B PE=2 SV=1 | 8 | Males and Females | | #N/A | 2.98E-07 |
| comp144423_c1_seq2 | 3.00E-97 | AM862425 | (sp:P50532) Structural maintenance of chromosomes protein 4 OS=Xenopus laevis GN=smc4 PE=1 SV=1 | 8 | Males and Females | | #N/A | 1.74E-07 |
| comp140479_c0_seq1 | 9.00E-110 | AM864373 | (sp:Q91917) DNA repair protein RAD51 homolog B OS=Xenopus laevis GN=rad51-B PE=2 SV=1 | 8 | Males and Females | | #N/A | 2.58E-08 |
| comp91488_c0_seq2 | 3.00E-73 | AM864330 | (sp:O73817) Proteasome subunit beta type-3 OS=Oncorhynchus mykiss GN=psmb3 PE=2 SV=1 | 8 | Males and Females | | #N/A | 6.14E-06 |
| comp132461_c0_seq1 | 7.00E-153 | AM858476 | (sp:Q8R323) Replication factor C subunit 3 OS=Mus musculus GN=Rfc3 PE=2 SV=1 | 8 | Males and Females | | #N/A | 1.66E-06 |
| comp136877_c1_seq2 | 4.00E-123 | AM858831 | (sp:P40937) Replication factor C subunit 5 OS=Homo sapiens GN=RFC5 PE=1 SV=1 | 8 | Males and Females | | #N/A | 1.87E-10 |
| comp120086_c0_seq1 | 2.00E-140 | CU992983 | (sp:Q9CPY6) Uncharacterized protein C17orf39 homolog OS=Mus musculus PE=2 SV=1 | 8 | Males and Females | | #N/A | 6.11E-07 |
| comp140093_c0_seq3 | 2.00E-74 | AM858776 | (sp:P07735) Glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic OS=Drosophila virilis GN=Gpdh PE=1 SV=3 | 8 | Males and Females | male gonad | #N/A | 6.44E-07 |
| comp28280_c0_seq1 | 2.00E-135 | AM868500 | (sp:P62335) 26S protease regulatory subunit S10B OS=Spermophilus tridecemlineatus GN=PSMC6 PE=2 SV=1 | 8 | Males and Females | | #N/A | 4.27E-06 |
| comp133131_c0_seq2 | 2.00E-100 | BQ426921 | (sp:P83941) Transcription elongation factor B polypeptide 1 OS=Rattus norvegicus GN=Tceb1 PE=1 SV=1 | 8 | Males and Females | | #N/A | 4.34E-09 |
| comp48421_c0_seq1 | 1.00E-102 | BQ427163 | (sp:Q5BJ65) Histone H2A.V OS=Xenopus tropicalis GN=h2afv PE=2 SV=3 | 8 | Males and Females | | #N/A | 6.84E-12 |
| comp140617_c0_seq2 | 0 | AM858396 | (sp:Q6P2U9) COP9 signalosome complex subunit 3 OS=Danio rerio GN=cops3 PE=2 SV=1 | 8 | Males and Females | | #N/A | 5.18E-06 |
| comp130760_c0_seq1 | 6.00E-111 | BQ426947 | (sp:O42149) Protein mago nashi homolog OS=Xenopus laevis GN=magoh PE=2 SV=1 | 8 | Males and Females | | #N/A | 1.82E-06 |
| comp137927_c0_seq1 | 4.00E-76 | AM869337 | (sp:Q29RZ2) Peptidylprolyl isomerase domain and WD repeat-containing protein 1 OS=Bos taurus GN=PPWD1 PE=2 SV=1 | 8 | Males and Females | male gonad | #N/A | 2.81E-08 |
| comp108941_c0_seq1 | 5.00E-109 | BQ426475 | (sp:Q9CZ15) DNA replication complex GINS protein PSF1 OS=Mus musculus GN=Gins1 PE=2 SV=1 | 8 | Males and Females | | #N/A | 3.69E-10 |
| comp136624_c0_seq1 | 0 | AM859534 | (sp:P46470) 26S protease regulatory subunit 8 OS=Xenopus laevis GN=psmc5 PE=2 SV=2 | 8 | Males and Females | | #N/A | 3.56E-06 |
| comp110084_c0_seq1 | 2.00E-91 | AM866236 | (sp:Q9Y248) DNA replication complex GINS protein PSF2 OS=Homo sapiens GN=GINS2 PE=1 SV=1 | 8 | Males and Females | | #N/A | 1.82E-11 |
| comp143167_c1_seq1 | 1.00E-134 | BQ426799 | (sp:P28075) Proteasome subunit beta type-5 OS=Rattus norvegicus GN=Psmb5 PE=1 SV=3 | 8 | Males and Females | | #N/A | 3.03E-08 |
| comp122176_c0_seq1 | 3.00E-67 | AM855687 | (sp:P61959) Small ubiquitin-related modifier 2 OS=Rattus norvegicus GN=Sumo2 PE=1 SV=1 | 9 | Males and Females | | #N/A | 6.91E-10 |
| comp135745_c0_seq1 | 1.00E-63 | AM862973 | (sp:Q9QYE0) Zinc finger protein PLAG1 OS=Mus musculus GN=Plag1 PE=2 SV=1 | 9 | Males and Females | | #N/A | 1.37E-07 |
| comp143111_c1_seq1 | 2.00E-99 | AM859520 | (sp:P30664) DNA replication licensing factor mcm4-B OS=Xenopus laevis GN=mcm4-B PE=1 SV=3 | 9 | Males and Females | | #N/A | 8.83E-08 |
| comp137929_c0_seq1 | 9.00E-92 | AM854229 | (sp:O44437) Small nuclear ribonucleoprotein Sm D3 OS=Drosophila melanogaster GN=SmD3 PE=1 SV=1 | 9 | Males and Females | | #N/A | 2.56E-06 |
| comp139145_c0_seq2 | 2.00E-90 | AM866997 | (sp:Q8BMB3) Eukaryotic translation initiation factor 4E type 2 OS=Mus musculus GN=Eif4e2 PE=1 SV=1 | 9 | Males and Females | | #N/A | 5.86E-06 |
| comp134037_c0_seq2 | 2.00E-79 | AM860755 | (sp:P60899) DNA-directed RNA polymerase II subunit RPB9 OS=Sus scrofa GN=POLR2I PE=3 SV=1 | 9 | Males and Females | | #N/A | 6.18E-06 |
| comp139393_c0_seq2 | 0 | FP089861 | (sp:Q24572) Probable histone-binding protein Caf1 OS=Drosophila melanogaster GN=Caf1 PE=1 SV=1 | 9 | Males and Females | | #N/A | 9.77E-07 |
| comp140689_c0_seq2 | 7.00E-119 | CU990820 | (sp:Q561P5) DNA replication licensing factor mcm5 OS=Xenopus tropicalis GN=mcm5 PE=2 SV=1 | 9 | Males and Females | | #N/A | 1.65E-12 |
| comp144251_c0_seq2 | 2.00E-107 | AM237674 | (sp:Q7ZXB1) DNA replication licensing factor mcm7-B OS=Xenopus laevis GN=mcm7-B PE=2 SV=1 | 9 | Males and Females | | #N/A | 4.98E-11 |
| comp139165_c0_seq2 | 5.00E-83 | AM237649 | (sp:P07201) Ribonucleoside-diphosphate reductase small chain OS=Spisula solidissima PE=2 SV=2 | 9 | Males and Females | | #N/A | 2.75E-13 |
| comp143445_c0_seq12 | 8.00E-111 | AM863306 | (sp:P83917) Chromobox protein homolog 1 OS=Mus musculus GN=Cbx1 PE=1 SV=1 | 9 | Males and Females | | #N/A | 2.27E-07 |
| comp144116_c0_seq6 | 3.00E-97 | AM861509 | (sp:Q6DIH3) DNA replication licensing factor mcm2 OS=Xenopus tropicalis GN=mcm2 PE=2 SV=1 | 9 | Males and Females | | #N/A | 1.30E-07 |
| comp116084_c0_seq1 | 6.00E-82 | AM860925 | (sp:Q28165) Polyadenylate-binding protein 2 OS=Bos taurus GN=PABPN1 PE=1 SV=3 | 9 | Males and Females | | #N/A | 2.92E-06 |
| comp141596_c0_seq6 | 1.00E-155 | AM858460 | (sp:P28021) Casein kinase II subunit beta OS=Xenopus laevis GN=csnk2b PE=1 SV=1 | 9 | Males and Females | | #N/A | 6.13E-06 |
| comp143362_c0_seq2 | 9.00E-65 | AM859331 | (sp:Q5R7Q4) Replication protein A 70 kDa DNA-binding subunit OS=Pongo abelii GN=RPA1 PE=2 SV=1 | 9 | Males and Females | | #N/A | 6.16E-06 |
| comp144251_c0_seq2 | 2.00E-99 | AM862562 | (sp:Q6NX31) DNA replication licensing factor mcm7 OS=Xenopus tropicalis GN=mcm7 PE=2 SV=1 | 9 | Males and Females | | #N/A | 0 |
| comp139393_c0_seq2 | 0 | CB617555 | (sp:Q09028) Histone-binding protein RBBP4 OS=Homo sapiens GN=RBBP4 PE=1 SV=3 | 9 | Males and Females | | #N/A | 1.95E-07 |
| comp144629_c0_seq1 | 3.00E-98 | CU686554 | (sp:Q7ZUY3) Histone H2A.x OS=Danio rerio GN=h2afx PE=2 SV=3 | 9 | Males and Females | | #N/A | 1.31E-08 |
| comp144423_c1_seq2 | 8.00E-108 | AM859381 | (sp:Q9FJL0) Structural maintenance of chromosomes protein 4 OS=Arabidopsis thaliana GN=SMC4 PE=2 SV=1 | 9 | Males and Females | | #N/A | 8.77E-08 |
| comp122176_c0_seq1 | 3.00E-67 | CU992682 | (sp:P61959) Small ubiquitin-related modifier 2 OS=Rattus norvegicus GN=Sumo2 PE=1 SV=1 | 9 | Males and Females | | #N/A | 2.65E-08 |
| comp141044_c0_seq2 | 1.00E-63 | CU685382 | (sp:Q9V3J8) Protein will die slowly OS=Drosophila melanogaster GN=wds PE=2 SV=1 | 9 | Males and Females | | #N/A | 3.72E-06 |
| comp141803_c0_seq1 | 1.00E-91 | DV736591 | (sp:Q5R637) T-complex protein 1 subunit delta OS=Pongo abelii GN=CCT4 PE=2 SV=3 | 9 | Males and Females | | #N/A | 5.93E-06 |
| comp122176_c0_seq1 | 5.00E-65 | FP011152 | (sp:P61959) Small ubiquitin-related modifier 2 OS=Rattus norvegicus GN=Sumo2 PE=1 SV=1 | 9 | Males and Females | female gonad | #N/A | 5.81E-06 |
| comp141861_c1_seq1 | 5.00E-152 | AM857246 | (sp:P60892) Ribose-phosphate pyrophosphokinase 1 OS=Rattus norvegicus GN=Prps1 PE=1 SV=2 | 9 | Males and Females | | #N/A | 7.94E-09 |
| comp141289_c0_seq6 | 3.00E-62 | CU998781 | (sp:P62311) U6 snRNA-associated Sm-like protein LSm3 OS=Mus musculus GN=Lsm3 PE=2 SV=2 | 9 | Males and Females | | #N/A | 2.55E-08 |
| comp134387_c0_seq1 | 1.00E-97 | CU996024 | (sp:Q08013) Translocon-associated protein subunit gamma OS=Rattus norvegicus GN=Ssr3 PE=1 SV=2 | 9 | Males and Females | | #N/A | 7.87E-08 |
| comp129247_c0_seq2 | 9.00E-110 | AM869433 | (sp:P28370) Probable global transcription activator SNF2L1 OS=Homo sapiens GN=SMARCA1 PE=1 SV=2 | 9 | Males and Females | female gonad | #N/A | 6.26E-07 |
| comp125113_c0_seq1 | 7.00E-62 | AM856760 | (sp:Q642A5) DNA polymerase epsilon subunit 3 OS=Rattus norvegicus GN=Pole3 PE=2 SV=1 | 9 | Males and Females | | #N/A | 1.23E-11 |
| comp140352_c2_seq9 | 2.00E-140 | FP000294 | (sp:Q1JPX3) Phenylalanyl-tRNA synthetase alpha chain OS=Danio rerio GN=farsa PE=2 SV=2 | 9 | Males and Females | | #N/A | 6.21E-06 |
| comp134387_c0_seq1 | 1.00E-96 | CX069186 | (sp:Q08013) Translocon-associated protein subunit gamma OS=Rattus norvegicus GN=Ssr3 PE=1 SV=2 | 9 | Males and Females | | #N/A | 8.42E-08 |
| comp132248_c0_seq1 | 2.00E-177 | AM856889 | (sp:Q9Z2U1) Proteasome subunit alpha type-5 OS=Mus musculus GN=Psma5 PE=1 SV=1 | 9 | Males and Females | | #N/A | 1.05E-06 |
| comp137842_c0_seq1 | 4.00E-128 | FP000131 | (sp:Q8BTM8) Filamin-A OS=Mus musculus GN=Flna PE=1 SV=4 | 10 | Males and Females | | Adductor muscle | 5.16E-06 |
| comp144461_c0_seq7 | 3.00E-87 | CU999937 | (sp:Q9Y490) Talin-1 OS=Homo sapiens GN=TLN1 PE=1 SV=3 | 10 | Males and Females | | Adductor muscle | 1.74E-06 |