# studies

dbdate: 04/16/2014
author: Chung CM
date: 03/03/2014
journal: Diabetes Metab Res Rev
link: http://www.ncbi.nlm.nih.gov/pubmed/24123702
trait: Resistin levels
initial_samplesize: 382 Han Chinese ancestry indiviudals
replication_samplesize: 559 Han Chinese ancestry indiviudals
study:
Common quantitative trait locus downstream of RETN gene identified by genome-wide association study is associated with risk of type 2 diabetes mellitus in Han Chinese: a Mendelian randomization effect.


dbdate: 08/02/2014
author: Ferreira MA
date: 12/30/2013
journal: J Allergy Clin Immunol
link: http://www.ncbi.nlm.nih.gov/pubmed/24388013
trait: Asthma and hay fever
initial_samplesize: 6,685 European ancestry cases, 14,091 European ancestry controls
replication_samplesize: 878 European ancestry cases, 2,455 European ancestry controls
study:
Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype.


dbdate: 08/02/2014
author: Zhou L
date: 12/30/2013
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/24386095
trait: Lipid traits
initial_samplesize: 3,451 Han Chinese ancestry individuals
replication_samplesize: 8,830 Han Chinese ancestry individuals
study:
A genome wide association study identifies common variants associated with lipid levels in the Chinese population.


dbdate: 08/05/2014
author: Okada Y
date: 12/25/2013
journal: Nature
link: http://www.ncbi.nlm.nih.gov/pubmed/24390342
study: Genetics of rheumatoid arthritis contributes to biology and drug discovery.
trait: Rheumatoid arthritis
initial_samplesize:
up to 14,361 European ancestry cases, up to 42,923 European ancestry controls, up to 4,873 East Asian ancestry cases, up to 17,642 East Asian ancestry controls

replication_samplesize:
up to 3,775 European ancestry cases, up to 5,801 European ancestry controls, up to 6,871 East Asian ancestry cases, up to 6,392 East Asian ancestry controls


dbdate: 08/02/2014
author: Williams AL
date: 12/25/2013
journal: Nature
link: http://www.ncbi.nlm.nih.gov/pubmed/24390345
study: Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico.
trait: Type 2 diabetes
initial_samplesize:
3,848 Mexican and other Latin American ancestry cases, 4,366 Mexican and other Latin American ancestry controls

replication_samplesize:
896 Mexican American cases, 832 Mexican American controls, 2,768 East Asian ancestry cases, 2,880 East Asian ancestry controls, 1,082 South Asian ancestry cases, 1,105 South Asian ancestry controls, 1,874 European ancestry cases, 1,333 European ancestry controls, 2,127 African American cases, 2,103 African American controls, 698 Native Hawaiian ancestry cases, 579 Native Hawaiian ancestry controls, 2,009 Singaporean cases, 1959 Singaporean controls


dbdate: 08/01/2014
author: Miki D
date: 12/20/2013
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/24376798
trait: Chronic hepatitis C infection
initial_samplesize: 481 Japanese ancestry cases, 2,963 Japanese ancestry controls
replication_samplesize: 5,737 Japanese ancestry cases, 26,931 Japanese ancestry controls
study:
HLA-DQB1*03 confers susceptibility to chronic hepatitis C in Japanese: a genome-wide association study.


dbdate: 08/03/2014
author: Rocanin-Arjo A
date: 12/19/2013
journal: Blood
link: http://www.ncbi.nlm.nih.gov/pubmed/24357727
trait: Thrombin generation potential phenotypes
initial_samplesize: 714 European ancestry venous thrombosis cases, 1,253 European ancestry individuals
replication_samplesize: 714 European ancestry venous thrombosis cases, 543 European ancestry individuals
study:
A meta-analysis of genome-wide association studies identifies ORM1 as a novel gene controlling thrombin generation potential.


dbdate: 08/05/2014
author: Nanayakkara S
date: 12/18/2013
journal: J Occup Health
link: http://www.ncbi.nlm.nih.gov/pubmed/24351856
trait: Chronic kidney disease
initial_samplesize: 301 Sinhalese Sri Lankan ancestry cases, 276 Sinhalese Sri Lankan ancestry controls
study:
An integrative study of the genetic, social and environmental determinants of chronic kidney disease characterized by tubulointerstitial damages in the North Central Region of Sri Lanka.


dbdate: 08/02/2014
author: Shaffer JR
date: 12/17/2013
journal: G3 (Bethesda)
link: http://www.ncbi.nlm.nih.gov/pubmed/24347629
trait: Periodontal disease-related phenotypes
initial_samplesize: 93 European ancestry cases, 83 European ancestry individuals, 497 European ancestry controls
study:
Genome-wide association study of periodontal health measured by probing depth in adults ages 18-49 years.


dbdate: 07/30/2014
author: Voruganti VS
date: 12/16/2013
journal: Front Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/24379826
trait: Serum uric acid levels
initial_samplesize: 632 Mexican American individuals
study:
Genome-wide association analysis confirms and extends the association of SLC2A9 with serum uric acid levels to Mexican Americans.


dbdate: 07/29/2014
author: Simino J
date: 12/12/2013
journal: Front Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/24376456
trait: Diastolic blood pressure (alcohol consumption interaction)
initial_samplesize: up to 6,882 European ancestry individuals
study:
Gene-alcohol interactions identify several novel blood pressure loci including a promising locus near SLC16A9.


dbdate: 07/28/2014
author: Winham SJ
date: 12/10/2013
journal: Mol Psychiatry
link: http://www.ncbi.nlm.nih.gov/pubmed/24322204
trait: Bipolar disorder (body mass index interaction)
initial_samplesize: 388 European ancestry cases, 1,020 European ancestry controls
study:
Genome-wide association study of bipolar disorder accounting for effect of body mass index identifies a new risk allele in TCF7L2.


dbdate: 07/29/2014
author: Purrington KS
date: 12/09/2013
journal: Carcinogenesis
link: http://www.ncbi.nlm.nih.gov/pubmed/24325915
initial_samplesize: 1,529 European ancestry cases, 3,399 European ancestry controls
replication_samplesize: 2,148 European ancestry cases, 1,309 European ancestry controls
study:
Genome-wide association study identifies 25 known breast cancer susceptibility loci as risk factors for triple-negative breast cancer.

trait:
Breast cancer (estrogen-receptor negative, progesterone-receptor negative, and human epidermal growth factor-receptor negative)


dbdate: 07/29/2014
author: van der Valk RJ
date: 12/05/2013
journal: J Allergy Clin Immunol
link: http://www.ncbi.nlm.nih.gov/pubmed/24315451
trait: Fractional exhaled nitric oxide (childhood)
initial_samplesize: 5,131 European ancestry individuals, 1,155 Hispanic individuals, 2,572 individuals
study:
Fraction of exhaled nitric oxide values in childhood are associated with 17q11.2-q12 and 17q12-q21 variants.


dbdate: 07/29/2014
author: An P
date: 12/04/2013
journal: Metabolism
link: http://www.ncbi.nlm.nih.gov/pubmed/24405752
trait: Glycated hemoglobin levels
initial_samplesize: 4,088 European ancestry non-diabetic elderly individuals
replication_samplesize: up to 47,822 European ancestry non-diabetic elderly individuals
study:
Genome-wide association study identifies common loci influencing circulating glycated hemoglobin (HbA1c) levels in non-diabetic subjects: the Long Life Family Study (LLFS).


dbdate: 07/26/2014
author: Yatagai Y
date: 12/04/2013
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/24324648
trait: IgE levels
initial_samplesize: 967 Japanese ancestry individuals, 213 Japanese ancestry asthmatics
replication_samplesize: 1,894 Japanese ancestry individuals, 580 Japanese ancestry asthmatics
study:
Genome-wide association study for levels of total serum IgE identifies HLA-C in a Japanese population.


dbdate: 07/29/2014
author: Namjou B
date: 12/03/2013
journal: Front Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/24348519
trait: Body mass index
initial_samplesize: up to 2,860 European ancestry children
study:
EMR-linked GWAS study: investigation of variation landscape of loci for body mass index in children.


dbdate: 08/06/2014
author: Domarkiene I
date: 12/01/2013
journal: Balkan J Med Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/24778558
trait: Coronary heart disease
initial_samplesize: 31 European ancestry cases and 63 European ancestry controls from 32 families
study:
RTN4 and FBXL17 Genes are Associated with Coronary Heart Disease in Genome-Wide Association Analysis of Lithuanian Families.


dbdate: 03/13/2014
author: Negi S
date: 12/01/2013
journal: Arthritis Rheum
link: http://www.ncbi.nlm.nih.gov/pubmed/23918589
trait: Rheumatoid arthritis
initial_samplesize: 706 North Indian ancestry cases, 761 North Indian ancestry controls
replication_samplesize: 927 North Indian ancestry cases, 1,148 North Indian ancestry controls
study:
A genome-wide association study reveals ARL15, a novel non-HLA susceptibility gene for rheumatoid arthritis in North Indians.


dbdate: 06/19/2014
author: Speedy HE
date: 12/01/2013
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/24292274
trait: Chronic lymphocytic leukemia
initial_samplesize: 1,739 European ancestry cases, 5,199 European ancestry controls
replication_samplesize: 1,144 European ancestry cases, 3,151 European ancestry controls
study:
A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia.


dbdate: 06/21/2014
author: Pan L
date: 11/28/2013
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/24282030
trait: Hepatitis B vaccine response
initial_samplesize: 108 Han Chinese ancestry high-responder cases, 77 Han Chinese ancestry non-responder controls
replication_samplesize: 1,336 Han Chinese ancestry high-responder cases, 420 Han Chinese ancestry non-responder controls
study:
A genome-wide association study identifies polymorphisms in the HLA-DR region associated with non-response to hepatitis B vaccination in Chinese Han populations.


dbdate: 07/25/2014
author: Boardman JD
date: 11/27/2013
journal: Demography
link: http://www.ncbi.nlm.nih.gov/pubmed/24281739
trait: Body mass index (education interaction)
initial_samplesize: 816 non-college graduate individuals and 1,061 college graduate individuals
study:
Is the gene-environment interaction paradigm relevant to genome-wide studies? The case of education and body mass index.


dbdate: 06/28/2014
author: Quillen EE
date: 11/26/2013
journal: Am J Med Genet B Neuropsychiatr Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/24277619
trait: Alcohol consumption (maxi-drinks)
initial_samplesize: 272 Han Chinese ancestry individuals
study:
ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural chinese sample.


dbdate: 06/28/2014
author: Ruderfer DM
date: 11/26/2013
journal: Mol Psychiatry
link: http://www.ncbi.nlm.nih.gov/pubmed/24280982
study: Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia.
trait: Schizophrenia or bipolar disorder
initial_samplesize:
up to 2,461 European ancestry schizophrenia cases, up to 6,908 schizophrenia cases, up to 4,903 European ancestry bipolar disorder cases, up to 5,507 bipolar disorder cases, up to 7,213 European ancestry controls, up to 12,210 controls


dbdate: 07/25/2014
author: Wu AC
date: 11/23/2013
journal: J Allergy Clin Immunol
link: http://www.ncbi.nlm.nih.gov/pubmed/24280104
trait: Bronchodilator response in asthma (inhaled corticosteroid treatment interaction)
initial_samplesize: 172 European ancestry cases, 409 European ancestry controls
replication_samplesize: 227 European ancestry cases
study:
Inhaled corticosteroid treatment modulates ZNF432 gene variant's effect on bronchodilator response in asthmatics.


dbdate: 07/23/2014
author: Dichgans M
date: 11/21/2013
journal: Stroke
link: http://www.ncbi.nlm.nih.gov/pubmed/24262325
trait: Coronary artery disease
initial_samplesize: 33,398 cases, 75,726 controls
study:
Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.


dbdate: 07/23/2014
author: Deng X
date: 11/20/2013
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/24324551
trait: Antibody status in Tripanosoma cruzi seropositivity
initial_samplesize: 580 Brazilian ancestry individuals
study:
Genome wide association study (GWAS) of Chagas cardiomyopathy in Trypanosoma cruzi seropositive subjects.


dbdate: 05/28/2014
author: Fogh I
date: 11/20/2013
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/24256812
trait: Amyotrophic lateral sclerosis (sporadic)
initial_samplesize: 6,100 European ancestry cases, 7,125 European ancestry controls
replication_samplesize: 2,074 European ancestry cases, 2,556 European ancestry controls
study:
A genome-wide association meta-analysis identifies a novel locus at 17q11.2 associated with sporadic amyotrophic lateral sclerosis.


dbdate: 07/22/2014
author: Lencz T
date: 11/19/2013
journal: Nat Commun
link: http://www.ncbi.nlm.nih.gov/pubmed/24253340
study: Genome-wide association study implicates NDST3 in schizophrenia and bipolar disorder.
trait: Schizophrenia
initial_samplesize: 904 Ashkenzai Jewish cases, 1,640 Ashkenzai Jewish controls
replication_samplesize:
3,944 European ancestry cases, 3,049 European ancestry controls, 921 African American cases, 954 African American controls, 550 Japanese ancestry cases, 530 Japanese ancestry controls


dbdate: 07/25/2014
author: Bonnelykke K
date: 11/17/2013
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/24241537
trait: Asthma (childhood, severe)
initial_samplesize: 1,173 European ancestry cases, 2,511 European ancestry controls
replication_samplesize: 7,178 European ancestry cases, 10,383 European ancestry controls, 63 cases, 3,605 controls
study:
A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations.


dbdate: 07/20/2014
author: Zhang L
date: 11/17/2013
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/24249740
study: Multistage genome-wide association meta-analyses identified two new loci for bone mineral density.
trait: Bone mineral density
initial_samplesize:
5,833 European ancestry females, 2,639 European ancestry males, 784 Han Chinese ancestry females, 763 Han Chinese ancestry males, 712 African American females, 409 Hispanic females

replication_samplesize:
7,010 European ancestry females, 3,772 European ancestry males, 2,980 East Asian ancestry females, 2,159 East Asian ancestry males


dbdate: 07/22/2014
author: Goris A
date: 11/13/2013
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/24234648
trait: Multiple sclerosis or amyotrophic lateral sclerosis
initial_samplesize: 4,088 Multiple sclerosis cases, 3,762 Amyotrophic lateralsclerosis cases, 12,030 controls
study:
No evidence for shared genetic basis of common variants in multiple sclerosis and amyotrophic lateral sclerosis.


dbdate: 07/22/2014
author: Chen P
date: 11/07/2013
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/24244560
trait: Glycated hemoglobin levels
study:
A study assessing the association of glycated hemoglobin A1C (HbA1C) associated variants with HbA1C, chronic kidney disease and diabetic retinopathy in populations of Asian ancestry.

initial_samplesize:
3,427 Chinese ancestry individuals, 1,735 Malay ancestry individuals, 1,520 Asian Indian ancestry individuals


dbdate: 05/13/2014
author: Behr ER
date: 11/06/2013
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/24223155
trait: Drug-induced torsades de pointes
study:
Genome wide analysis of drug-induced torsades de pointes: lack of common variants with large effect sizes.

initial_samplesize:
216 European ancestry cases, 386 European ancestry drug-exposed controls, 385 European ancestry population controls


dbdate: 07/23/2014
author: Xia K
date: 11/05/2013
journal: Mol Psychiatry
link: http://www.ncbi.nlm.nih.gov/pubmed/24189344
study: Common genetic variants on 1p13.2 associate with risk of autism.
trait: Autism
replication_samplesize: 1,299 cases and 2,598 controls from 1,299 European ancestry trios
initial_samplesize:
275 cases and 550 controls from 275 Chinese ancestry trios, 136 Chinese ancestry cases, 984 Chinese ancestry controls


dbdate: 04/02/2014
author: Rudolph A
date: 11/04/2013
journal: Endocr Relat Cancer
link: http://www.ncbi.nlm.nih.gov/pubmed/24080446
trait: Breast cancer (menopausal hormone therapy interaction)
initial_samplesize: 2,920 European ancestry cases
replication_samplesize: 7,689 European ancestry cases, 9,266 European ancestry controls
study:
Genetic modifiers of menopausal hormone replacement therapy and breast cancer risk: a genome-wide interaction study.


dbdate: 06/26/2014
author: Cornejo-Garcia JA
date: 11/01/2013
journal: Pharmacogenomics
link: http://www.ncbi.nlm.nih.gov/pubmed/24236485
trait: Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced)
study:
Genome-wide association study in NSAID-induced acute urticaria/angioedema in Spanish and Han Chinese populations.

initial_samplesize:
112 European ancestry cases, 124 European ancestry controls, 120 Han Chinese ancestry cases, 101 Han Chinese ancestry controls


dbdate: 04/15/2014
author: Haga S
date: 10/31/2013
journal: J Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/24172245
study: A genome-wide association study of third molar agenesis in Japanese and Korean populations.
trait: Tooth agenesis (mandibular third molar)
replication_samplesize: N/A
initial_samplesize:
80 East Asian ancestry mandibular cases, 69 East Asian ancestry maxillary cases, 338 East Asian ancestry controls


dbdate: 05/13/2014
author: Han F
date: 10/31/2013
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/24204295
trait: Narcolepsy
initial_samplesize: 1,189 Chinese ancestry cases, 1,997 Chinese ancestry controls
replication_samplesize: 2,693 European ancestry cases, 11,495 European ancestry controls
study:
Genome wide analysis of narcolepsy in China implicates novel immune loci and reveals changes in association prior to versus after the 2009 H1N1 influenza pandemic.


dbdate: 05/03/2014
author: Sleiman P
date: 10/29/2013
journal: Sci Rep
link: http://www.ncbi.nlm.nih.gov/pubmed/24166486
study: GWAS meta analysis identifies TSNARE1 as a novel Schizophrenia / Bipolar susceptibility locus.
trait: Schizophrenia, schizoaffective disorder or bipolar disorder
replication_samplesize: 2652 individuals
initial_samplesize:
11,985 schizophrenia cases, 377 schizoaffective disorder cases, 1,032 bipolar disorder cases, 34,676 controls


dbdate: 04/26/2014
author: He J
date: 10/28/2013
journal: Circ Cardiovasc Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/24165912
trait: Blood pressure measurement (cold pressor test)
initial_samplesize: 1,881 Han Chinese ancestry individuals
replication_samplesize: 698 Han Chinese ancestry individuals
study:
Genome-wide association study identifies 8 novel loci associated with blood pressure responses to interventions in Han Chinese.


dbdate: 05/13/2014
author: Zheng JS
date: 10/28/2013
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/24204828
trait: Fasting insulin (interaction)
initial_samplesize: 820 European ancestry individuals
study:
Genome-wide contribution of genotype by environment interaction to variation of diabetes-related traits.


dbdate: 04/15/2014
author: Hu Z
date: 10/27/2013
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/24162738
study: New loci associated with chronic hepatitis B virus infection in Han Chinese.
trait: Hepatitis B
initial_samplesize: 951 Han Chinese ancestry HBV carrier cases, 937 Han Chinese ancestry HBV cleared controls
replication_samplesize:
4,230 Chinese ancestry HBV carrier cases, 3,051 Chinese ancestry HBV cleared controls, 2,622 Chinese ancestry controls


dbdate: 05/02/2014
author: Seppala I
date: 10/24/2013
journal: Eur Heart J
link: http://www.ncbi.nlm.nih.gov/pubmed/24159190
trait: Serum dimethylarginine levels (asymmetric)
initial_samplesize: 5110 European ancestry individuals
study:
Genome-wide association study on dimethylarginines reveals novel AGXT2 variants associated with heart rate variability but not with overall mortality.


dbdate: 04/15/2014
author: Goodbourn PT
date: 10/23/2013
journal: Genes Brain Behav
link: http://www.ncbi.nlm.nih.gov/pubmed/24152035
trait: Contrast sensitivity
initial_samplesize: 985 European ancestry individuals
replication_samplesize: N/A
study:
Variants in the 1q21 risk region are associated with a visual endophenotype of autism and schizophrenia.


dbdate: 04/25/2014
author: Gelernter J
date: 10/19/2013
journal: Biol Psychiatry
link: http://www.ncbi.nlm.nih.gov/pubmed/24143882
trait: Opioid sensitivity
replication_samplesize: 2,116 European ancestry individuals, 4,496 African American individuals
study:
Genome-wide association study of opioid dependence: multiple associations mapped to calcium and potassium pathways.

initial_samplesize:
1,383 European ancestry cases, 996 European ancestry controls, 683 African American cases, 2,635 African Amercian controls


dbdate: 04/26/2014
author: Wu Y
date: 10/14/2013
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/24105470
trait: Adiponectin levels
initial_samplesize: 6,110 East Asian ancestry individuals, 1,717 Filipino ancestry individuals
replication_samplesize: 10,252 East Asian ancestry individuals
study:
A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2.


dbdate: 04/10/2014
author: Levine DM
date: 10/13/2013
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/24121790
trait: Barrett's esophagus
initial_samplesize: 2,416 European ancestry cases, 3,206 European ancestry controls
replication_samplesize: 759 European ancestry cases, 6,911 European ancestry controls
study:
A genome-wide association study identifies new susceptibility loci for esophageal adenocarcinoma and Barrett's esophagus.


dbdate: 04/11/2014
author: Jones RM
date: 10/11/2013
journal: Front Hum Neurosci
link: http://www.ncbi.nlm.nih.gov/pubmed/24133439
trait: Social autistic-like traits
initial_samplesize: 965 European ancestry young adults
study:
Genome-wide association study of autistic-like traits in a general population study of young adults.


dbdate: 04/25/2014
author: Pei YF
date: 10/08/2013
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/24064335
study: Meta-analysis of genome-wide association data identifies novel susceptibility loci for obesity.
trait: Body mass index
replication_samplesize: 4,979 European ancestry individuals, 2,740 Han Chinese ancestry individuals
initial_samplesize:
8,463 European ancestry individuals, 7,478 African American individuals, 3,348 Hispanic individuals, 1,624 Han Chinese ancestry individuals


dbdate: 04/08/2014
author: Song YQ
date: 10/08/2013
journal: J Clin Invest
link: http://www.ncbi.nlm.nih.gov/pubmed/24216480
study: Lumbar disc degeneration is linked to a carbohydrate sulfotransferase 3 variant.
trait: Disc degeneration (lumbar)
initial_samplesize: 366 Japanese ancestry cases, 3,331 Japanese ancestry controls
replication_samplesize:
1,628 East Asian ancestry cases, 17,469 East Asian ancestry controls, 399 European ancestry cases, 5,035 European ancestry control


dbdate: 05/01/2014
author: Hanson RL
date: 10/07/2013
journal: Diabetes
link: http://www.ncbi.nlm.nih.gov/pubmed/24101674
trait: Type 2 diabetes
study:
A genome-wide association study in American Indians implicates DNER as a susceptibility locus for type 2 diabetes.

initial_samplesize:
278 American Indian ancestry young-onset cases, 129 American Indian ancestry cases, and 424 American Indian ancestry controls from 514 sibships

replication_samplesize:
1,273 American Indian ancestry cases, 1,635 American Indian ancestry controls, 793 cases, 3,133 controls


dbdate: 04/04/2014
author: Li Y
date: 10/06/2013
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/24097066
trait: Sj�gren's syndrome
initial_samplesize: 542 Han Chinese ancestry cases, 1,050 Han Chinese ancestry controls
replication_samplesize: 1,303 Han Chinese ancestry cases, 2,727 Han Chinese ancestry controls
study:
A genome-wide association study in Han Chinese identifies a susceptibility locus for primary Sj&#x000f6;gren's syndrome at 7q11.23.


dbdate: 03/26/2014
author: Hong KW
date: 09/30/2013
journal: Genomics Inform
link: http://www.ncbi.nlm.nih.gov/pubmed/24124408
trait: Orthostatic hypotension
initial_samplesize: 667 Korean ancestry cases, 5,761 Korean ancestry controls
study:
Genome-wide association study of orthostatic hypotension and supine-standing blood pressure changes in two korean populations.


dbdate: 04/04/2014
author: Orozco G
date: 09/24/2013
journal: Arthritis Rheumatol
link: http://www.ncbi.nlm.nih.gov/pubmed/24449572
trait: Rheumatoid arthritis
initial_samplesize: 3,034 European ancestry cases, 5,271 European ancestry controls
replication_samplesize: 4,726 European ancestry cases, 2,625 European ancestry controls
study:
Novel rheumatoid arthritis susceptibility locus at 22q12 identified in an extended UK genome-wide association study.


dbdate: 04/09/2014
author: Wang Q
date: 09/24/2013
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/24086445
trait: Gray matter volume (schizophrenia interaction)
initial_samplesize: 74 Han Chinese ancestry cases, 51 Han Chinese ancestry controls
study:
Genome-wide association analysis with gray matter volume as a quantitative phenotype in first-episode treatment-na&#x000ef;ve patients with schizophrenia.


dbdate: 03/27/2014
author: O'Seaghdha CM
date: 09/19/2013
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/24068962
trait: Calcium levels
initial_samplesize: 39,400 European ancestry individuals
replication_samplesize: Up to 21,679 European ancestry individuals
study:
Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations.


dbdate: 04/04/2014
author: Chen Z
date: 09/18/2013
journal: J Med Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/24049095
trait: Follicule stimulating hormone
initial_samplesize: 1,999 Han Chinese ancestry individuals
replication_samplesize: 1,496 East Asian ancestry individuals
study:
Genome-wide association study of sex hormones, gonadotropins and sex hormone-binding protein in Chinese men.


dbdate: 04/10/2014
author: Chimusa ER
date: 09/18/2013
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/24057671
trait: Tuberculosis
initial_samplesize: 642 South African coloured cases, 91 South African coloured controls
study:
Genome-wide association study of ancestry-specific TB risk in the South African Coloured population.


dbdate: 03/26/2014
author: Kleber ME
date: 09/18/2013
journal: Circ Cardiovasc Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/24047826
trait: Homoarginine levels
initial_samplesize: 5,143 European ancestry individuals
replication_samplesize: 1,474 European ancestry individuals
study:
Genome-wide association study identifies 3 genomic loci significantly associated with serum levels of homoarginine: the AtheroRemo Consortium.


dbdate: 03/23/2014
author: Pyun JA
date: 09/16/2013
journal: Menopause
link: http://www.ncbi.nlm.nih.gov/pubmed/24045676
trait: Menopause (age at onset)
initial_samplesize: 1,827 Korean ancestry females
study:
Genome-wide association studies and epistasis analyses of candidate genes related to age at menarche and age at natural menopause in a Korean population.


dbdate: 04/01/2014
author: McGrath LM
date: 09/13/2013
journal: Am J Med Genet B Neuropsychiatr Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/24039173
trait: Functional impairment in major depressive disorder, bipolar disorder and schizophrenia
initial_samplesize: 2,246 European ancestry individuals
study:
Genetic predictors of risk and resilience in psychiatric disorders: a cross-disorder genome-wide association study of functional impairment in major depressive disorder, bipolar disorder, and schizophrenia.


dbdate: 03/22/2014
author: Sandholm N
date: 09/12/2013
journal: J Am Soc Nephrol
link: http://www.ncbi.nlm.nih.gov/pubmed/24029427
study: Chromosome 2q31.1 associates with ESRD in women with type 1 diabetes.
trait: End-stage renal disease in Type 1 diabetics
initial_samplesize:
258 European ancestry female cases, 935 European ancestry female controls, 387 European ancestry male cases, 655 European ancestry male controls

replication_samplesize:
178 European ancestry female cases, 594 European ancestry female controls, 251 European ancestry male cases, 494 European ancestry male controls, 252 female cases, 479 female controls, 256 male cases, 342 male controls


dbdate: 03/25/2014
author: Shameer K
date: 09/12/2013
journal: Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/24026423
trait: Mean platelet volume
initial_samplesize: 6,291 European ancestry individuals
study:
A genome- and phenome-wide association study to identify genetic variants influencing platelet count and volume and their pleiotropic effects.


dbdate: 04/04/2014
author: Wu Y
date: 09/10/2013
journal: J Lipid Res
link: http://www.ncbi.nlm.nih.gov/pubmed/24023260
trait: Lipid traits
initial_samplesize: 1,782 Filipino ancestry mothers
replication_samplesize: 1,719 Filipino ancestry offsprings
study:
Genetic association with lipids in Filipinos: waist circumference modifies an APOA5 effect on triglyceride levels.


dbdate: 03/22/2014
author: Kasperaviciute D
date: 09/06/2013
journal: Brain
link: http://www.ncbi.nlm.nih.gov/pubmed/24014518
trait: Mesial temporal lobe epilepsy with hippocampal sclerosis
initial_samplesize: up to 1,018 European ancestry cases, 7,552 European ancestry controls
replication_samplesize: 959 European ancestry cases, 3,591 European ancestry controls
study:
Epilepsy, hippocampal sclerosis and febrile seizures linked by common genetic variation around SCN1A.


dbdate: 04/02/2014
author: Miyake A
date: 09/04/2013
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/24023777
trait: Adolescent idiopathic scoliosis (severe)
initial_samplesize: 554 Japanese ancestry cases, 1,474 Japanese ancestry controls
replication_samplesize: 839 East Asian ancestry cases, 10,149 East Asian ancestry controls
study:
Identification of a susceptibility locus for severe adolescent idiopathic scoliosis on chromosome 17q24.3.


dbdate: 03/26/2014
author: Kelly TN
date: 09/03/2013
journal: Hypertension
link: http://www.ncbi.nlm.nih.gov/pubmed/24001895
trait: Blood pressure
initial_samplesize: 22,275 East Asian ancestry individuals, 4,325 South East Asian ancestry individuals
replication_samplesize: 28,783 East Asian ancestry individuals
study:
Genome-wide association study meta-analysis reveals transethnic replication of mean arterial and pulse pressure loci.


dbdate: 12/10/2013
author: Xie G
date: 09/01/2013
journal: Arthritis Rheum
link: http://www.ncbi.nlm.nih.gov/pubmed/23740775
trait: Wegener's granulomatosis
initial_samplesize: 459 European ancestry cases, 1,503 European ancestry controls
replication_samplesize: 291 European ancestry cases, 317 European ancestry controls
study:
Association of granulomatosis with polyangiitis (Wegener's) with HLA-DPB1*04 and SEMA6A gene variants: evidence from genome-wide analysis.


dbdate: 03/15/2014
author: Jiang J
date: 08/30/2013
journal: Front Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/24009623
trait: Response to mTOR inhibitor (everolimus)
study:
Genome-wide association study for biomarker identification of Rapamycin and Everolimus using a lymphoblastoid cell line system.

initial_samplesize:
87 European ancestry individuals, 91 African American individuals, 94 Han Chinese ancestry individuals


dbdate: 03/18/2014
author: Migliorini G
date: 08/30/2013
journal: Blood
link: http://www.ncbi.nlm.nih.gov/pubmed/23996088
trait: Acute lymphoblastic leukemia (B-cell precursor)
initial_samplesize: 1,658 European ancestry child cases, 4,723 European ancestry controls
replication_samplesize: 1,449 European ancestry child cases, 1,488 European ancestry controls
study:
Variation at 10p12.2 and 10p14 influences risk of childhood B-cell acute lymphoblastic leukemia and phenotype.


dbdate: 03/18/2014
author: Evangelou E
date: 08/29/2013
journal: Ann Rheum Dis
link: http://www.ncbi.nlm.nih.gov/pubmed/23989986
trait: Osteoarthritis (hip)
initial_samplesize: up to 4,734 European ancestry cases, up to 46,903 European ancestry controls
replication_samplesize: up to 6,928 European ancestry cases, up to 20,570 European ancestry controls
study:
A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip.


dbdate: 03/14/2014
author: Himes BE
date: 08/28/2013
journal: BMC Med Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23984888
study: ITGB5 and AGFG1 variants are associated with severity of airway responsiveness.
trait: Airway hyperresponsiveness
initial_samplesize: 994 European ancestry asthma cases
replication_samplesize:
650 European ancestry asthma cases, 3,354 European ancestry chronic obstructive pulmonary disease cases


dbdate: 03/14/2014
author: Qi L
date: 08/28/2013
journal: JAMA
link: http://www.ncbi.nlm.nih.gov/pubmed/23982368
trait: Cardiovascular heart disease in diabetics
initial_samplesize: 669 European ancestry cases, 1,641 European ancestry controls
replication_samplesize: 848 European ancestry cases, 1,030 European ancestry controls
study:
Association between a genetic variant related to glutamic acid metabolism and coronary heart disease in individuals with type 2 diabetes.


dbdate: 03/14/2014
author: Miller FW
date: 08/27/2013
journal: Arthritis Rheum
link: http://www.ncbi.nlm.nih.gov/pubmed/23983088
trait: Dermatomyositis
initial_samplesize: 1,178 European ancestry cases, 4,724 European ancestry controls
study:
Genome-wide association study of dermatomyositis reveals genetic overlap with other autoimmune disorders.


dbdate: 03/18/2014
author: Ripke S
date: 08/25/2013
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23974872
study: Genome-wide association analysis identifies 13 new risk loci for schizophrenia.
trait: Schizophrenia
initial_samplesize: 5,001 European ancestry cases, 6,243 European ancestry controls, 8,832 cases, 12,067 controls
replication_samplesize:
4,801 European ancestry cases, 4,741 European ancestry controls, 2,612 cases, 15,021 controls, 581 trios


dbdate: 03/19/2014
author: Allen EK
date: 08/23/2013
journal: J Assoc Res Otolaryngol
link: http://www.ncbi.nlm.nih.gov/pubmed/23974705
trait: Otitis media (chronic/recurrent)
initial_samplesize: 373 cases and 229 controls from 143 families
replication_samplesize: 932 European ancestry cases and 652 European ancestry controls from 441 families
study:
A genome-wide association study of chronic otitis media with effusion and recurrent otitis media identifies a novel susceptibility locus on chromosome 2.


dbdate: 03/14/2014
author: Sabater-Lleal M
date: 08/22/2013
journal: Circulation
link: http://www.ncbi.nlm.nih.gov/pubmed/23969696
trait: Fibrinogen
initial_samplesize: 91,323 European ancestry individuals
replication_samplesize: 8,423 African American individuals, 1,447 Hispanic individuals
study:
Multiethnic meta-analysis of genome-wide association studies in &gt;100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease.


dbdate: 03/21/2014
author: Feenstra B
date: 08/21/2013
journal: JAMA
link: http://www.ncbi.nlm.nih.gov/pubmed/23989729
trait: Infantile hypertrophic pyloric stenosis
initial_samplesize: 1,001 European ancestry cases, 2,371 European ancestry controls
study:
Plasma lipids, genetic variants near APOA1, and the risk of infantile hypertrophic pyloric stenosis.

replication_samplesize:
925 European ancestry cases, 1,621 European ancestry controls, 738 other ancestry cases, 697 other ancestry controls


dbdate: 03/15/2014
author: Franceschini N
date: 08/20/2013
journal: Am J Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23972371
trait: Blood pressure
initial_samplesize: 28,190 African American individuals, 1,188 Nigerian ancestry individuals
study:
Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations.

replication_samplesize:
69,395 European ancestry individuals, 5,266 African American individuals, 6,497 African ancestry individuals, 19,601 East Asian ancestry individuals


dbdate: 03/20/2014
author: Gelernter J
date: 08/20/2013
journal: Mol Psychiatry
link: http://www.ncbi.nlm.nih.gov/pubmed/23958962
trait: Cocaine dependence
replication_samplesize: 4,498 European ancestry individuals, 2,114 African American individuals
study:
Genome-wide association study of cocaine dependence and related traits: FAM53B identified as a risk gene.

initial_samplesize:
1,809 European ancestry cases, 570 European ancestry controls, 2,482 African American cases, 836 African American controls


dbdate: 03/13/2014
author: Ledda M
date: 08/20/2013
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23966204
trait: Bitter taste perception
initial_samplesize: 503 Brazillian ancestry individuals
replication_samplesize: 104 Brazillian ancestry individuals
study:
GWAS of human bitter taste perception identifies new loci and reveals additional complexity of bitter taste genetics.


dbdate: 03/20/2014
author: Speed D
date: 08/19/2013
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23962720
trait: Epilepsy (remission after treatment)
initial_samplesize: 889 Epilepsy cases
study:
A genome-wide association study and biological pathway analysis of epilepsy prognosis in a prospective cohort of newly treated epilepsy.


dbdate: 03/11/2014
author: Hara K
date: 08/14/2013
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23945395
study: Genome-wide association study identifies three novel loci for type 2 diabetes.
trait: Type 2 diabetes
initial_samplesize: 5,976 Japanese ancestry cases, 20,829 Japanese ancestry controls
replication_samplesize:
18,207 Japanese ancestry cases, 6,780 Japanese ancestry controls, 6,209 Chinese ancestry cases, 7,205 Chinese ancestry controls


dbdate: 03/04/2014
author: Yu B
date: 08/11/2013
journal: Genet Epidemiol
link: http://www.ncbi.nlm.nih.gov/pubmed/23934736
trait: Metabolite levels (X-11787)
initial_samplesize: 1,260 African American individuals
study:
Genome-wide association study of a heart failure related metabolomic profile among African Americans in the Atherosclerosis Risk in Communities (ARIC) study.


dbdate: 02/25/2014
author: Cheng CY
date: 08/08/2013
journal: Am J Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/24144296
trait: Axial length
initial_samplesize: 12,531 European ancestry individuals
replication_samplesize: 8,216 Asian ancestry individuals
study:
Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.


dbdate: 03/20/2014
author: Ostensson M
date: 08/02/2013
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/23936387
trait: Celiac disease
initial_samplesize: 206 European ancestry trios
study:
A possible mechanism behind autoimmune disorders discovered by genome-wide linkage and association analysis in celiac disease.


dbdate: 03/01/2014
author: Hayes MG
date: 07/31/2013
journal: Diabetes
link: http://www.ncbi.nlm.nih.gov/pubmed/23903356
trait: Glycemic traits (pregnancy)
replication_samplesize: 2,798 European ancestry individuals, 228 French Canadian founder population individuals
study:
Identification of HKDC1 and BACE2 as genes influencing glycemic traits during pregnancy through genome-wide association studies.

initial_samplesize:
1,367 European ancestry individuals, 817 Hispanic individuals, 1,075 Afro-Caribbean ancestry individuals, 1,178 Thai ancestry individuals


dbdate: 02/25/2014
author: Kim DS
date: 07/31/2013
journal: Int Arch Allergy Immunol
link: http://www.ncbi.nlm.nih.gov/pubmed/23921680
trait: Allergic dermatitis (nickel)
initial_samplesize: up to 24 Korean ancestry cases, 52 Korean ancestry controls
study:
A genome-wide association study in Koreans identifies susceptibility loci for allergic nickel dermatitis.


dbdate: 02/21/2014
author: McRae JF
date: 07/31/2013
journal: Curr Biol
link: http://www.ncbi.nlm.nih.gov/pubmed/23910658
trait: Odorant perception (&beta;-damascenone)
initial_samplesize: 187 European ancestry individuals
replication_samplesize: 89 European ancestry individuals
study:
Identification of regions associated with variation in sensitivity to food-related odors in the human genome.


dbdate: 02/18/2014
author: Pistis G
date: 07/31/2013
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/23935956
trait: Red blood cell traits
initial_samplesize: 1,664 Val Borbera individuals
replication_samplesize: 619 Friuli Venezia Giulia individuals, 16,145 European ancestry individuals
study:
Genome wide association analysis of a founder population identified TAF3 as a gene for MCHC in humans.


dbdate: 03/02/2014
author: Pooley KA
date: 07/29/2013
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23900074
trait: Telomere length
initial_samplesize: 2,240 European ancestry individuals
replication_samplesize: 11,024 breast cancer cases, 15,065 controls
study:
A genome-wide association scan (GWAS) for mean telomere length within the COGS project: identified loci show little association with hormone-related cancer risk.


dbdate: 02/08/2014
author: Wang H
date: 07/29/2013
journal: Pediatrics
link: http://www.ncbi.nlm.nih.gov/pubmed/23897914
study: A genome-wide association study (GWAS) for bronchopulmonary dysplasia.
trait: Bronchopulmonary dysplasia
replication_samplesize: 371 newborn cases, 424 newborn controls
initial_samplesize:
117 African American newborn cases, 108 African American newborn controls, 448 Hispanic newborn cases, 460 Hispanic newborn controls, 74 Asian or Pacific Islander ancestry newborn cases, 93 Asian or Pacific Islander ancestry newborn control, 174 European ancestry newborn cases, 216 European ancestry newborn controls, 14 newborn cases, 22 newborn controls


dbdate: 02/25/2014
author: McLaren PJ
date: 07/25/2013
journal: PLoS Pathog
link: http://www.ncbi.nlm.nih.gov/pubmed/23935489
trait: HIV-1 susceptibility
initial_samplesize: 6,334 European ancestry cases, 7,247 European ancestry controls
study:
Association study of common genetic variants and HIV-1 acquisition in 6,300 infected cases and 7,200 controls.


dbdate: 02/11/2014
author: Weidinger S
date: 07/25/2013
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23886662
trait: Atopic dermatitis
initial_samplesize: 1563 European ancestry cases, 4,054 European ancestry controls
replication_samplesize: 2,286 European ancestry cases, 3,160 European ancestry controls
study:
A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis.


dbdate: 01/22/2014
author: Bezzina CR
date: 07/21/2013
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23872634
trait: Brugada syndrome
initial_samplesize: 312 European ancestry cases, 1,115 European ancestry controls
study:
Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death.

replication_samplesize:
594 European ancestry cases, 806 European ancestry controls, 208 Japanese ancestry cases, 1,1016 Japanese controls


dbdate: 02/04/2014
author: Power RA
date: 07/15/2013
journal: Am J Med Genet B Neuropsychiatr Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23857890
trait: Major depressive disorder
initial_samplesize: 805 European ancestry cases, 805 European ancestry controls
study:
Genome-wide association analysis accounting for environmental factors through propensity-score matching: application to stressful live events in major depressive disorder.


dbdate: 02/04/2014
author: Yang SK
date: 07/14/2013
journal: Gut
link: http://www.ncbi.nlm.nih.gov/pubmed/23850713
trait: Crohn's disease
initial_samplesize: 532 Korean ancestry cases, 733 Korean ancestry controls
replication_samplesize: 1,779 Korean ancestry cases, 1,709 Korean ancestry controls
study:
Genome-wide association study of Crohn's disease in Koreans revealed three new susceptibility loci and common attributes of genetic susceptibility across ethnic populations.


dbdate: 02/12/2014
author: Kobayashi D
date: 07/08/2013
journal: Mol Pain
link: http://www.ncbi.nlm.nih.gov/pubmed/23834954
trait: Sensory disturbances after bilateral sagittal split ramus osteotomy
initial_samplesize: Up to 105 individuals
replication_samplesize: Up to 200 individuals
study:
Genome-wide association study of sensory disturbances in the inferior alveolar nerve after bilateral sagittal split ramus osteotomy.


dbdate: 02/05/2014
author: The Blue Mountains Eye Study (BMES) and The Wellcome Trust Case Control Consortium 2 (WTCCC2)
date: 07/07/2013
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23836780
trait: Intraocular pressure
initial_samplesize: 2,175 European ancestry individuals
replication_samplesize: 4,866 European ancestry individuals
study:
Genome-wide association study of intraocular pressure identifies the GLCCI1/ICA1 region as a glaucoma susceptibility locus.


dbdate: 02/06/2014
author: Ding L
date: 07/05/2013
journal: Hum Genomics
link: http://www.ncbi.nlm.nih.gov/pubmed/23829686
trait: Asthma (childhood onset)
initial_samplesize: 429 European ancestry affected offspring trios
replication_samplesize: 52 African American affected offspring trios, 46 Hispanic affected offspring trios
study:
Rank-based genome-wide analysis reveals the association of ryanodine receptor-2 gene variants with childhood asthma among human populations.


dbdate: 01/31/2014
author: van Meurs JB
date: 07/03/2013
journal: Am J Clin Nutr
link: http://www.ncbi.nlm.nih.gov/pubmed/23824729
trait: Homocysteine levels
initial_samplesize: 44,147 European ancestry individuals
study:
Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease.


dbdate: 01/10/2014
author: Dorajoo R
date: 07/02/2013
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/23844046
trait: C-reactive protein
study:
Are C-reactive protein associated genetic variants associated with serum levels and retinal markers of microvascular pathology in Asian populations from Singapore?

initial_samplesize:
2,179 Chinese ancestry individuals, 2,275 Malay ancestry individuals, 2,238 Asian Indian ancestry individuals


dbdate: 01/08/2014
author: Bonnelykke K
date: 06/30/2013
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23817571
trait: Allergic sensitization
initial_samplesize: 5,789 European ancestry cases, 10,056 European ancestry controls
replication_samplesize: 6,114 European ancestry cases, 9,920 European ancestry controls
study:
Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization.


dbdate: 01/09/2014
author: Hinds DA
date: 06/30/2013
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23817569
trait: Self-reported allergy
initial_samplesize: 53,862 European ancestry individuals
study:
A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci.


dbdate: 12/12/2013
author: Shi Y
date: 06/30/2013
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23817570
trait: Cervical cancer
initial_samplesize: Up to 1,364 Han Chinese ancestry cases, up to 3,028 Han Chinese ancestry controls
replication_samplesize: 4,167 Han Chinese ancestry cases, 7,196 Han Chinese ancestry controls
study:
A genome-wide association study identifies two new cervical cancer susceptibility loci at 4q12 and 17q12.


dbdate: 12/12/2013
author: Leandro-Garcia LJ
date: 06/17/2013
journal: J Med Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23776197
trait: Paclitaxel-induced neuropathy
initial_samplesize: 143 European ancestry individuals
study:
Genome-wide association study identifies ephrin type A receptors implicated in paclitaxel induced peripheral sensory neuropathy.


dbdate: 12/11/2013
author: Kim YJ
date: 06/10/2013
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23760081
trait: Chronic hepatitis B infection
initial_samplesize: 400 Korean ancestry cases, 1,000 Korean ancestry controls
replication_samplesize: 971 Korean ancestry cases, 1,938 Korean ancestry controls
study:
A genome-wide association study identified new variants associated with the risk of chronic hepatitis B.


dbdate: 12/11/2013
author: Martin JE
date: 06/10/2013
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23740937
trait: Systemic lupus erythematosus and Systemic sclerosis
study:
A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility loci.

initial_samplesize:
up to 2,761 European ancestry systemic sclerosis cases, 769 European ancestry systemic lupus erythematosus cases, 7,381 European ancestry controls

replication_samplesize:
up to 1,578 European ancestry systemic sclerosis cases, 1,727 European ancestry systemic lupus erythematosus cases, 6,893 European ancestry controls


dbdate: 12/05/2013
author: Turner ST
date: 06/10/2013
journal: Hypertension
link: http://www.ncbi.nlm.nih.gov/pubmed/23753411
trait: Response to diuretic therapy in hypertension
initial_samplesize: 424 European ancestry individuals
replication_samplesize: 841 European ancestry individuals
study:
Genomic association analysis of common variants influencing antihypertensive response to hydrochlorothiazide.


dbdate: 12/05/2013
author: Tan DE
date: 06/09/2013
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23749188
trait: B cell non-Hodgkin lymphoma
initial_samplesize: 253 Singaporean Chinese ancestry cases; 1,438 Singaporean Chinese ancestry controls
replication_samplesize: 1,175 Han Chinese ancestry cases, 5,492 Han Chinese ancestry controls
study:
Genome-wide association study of B cell non-Hodgkin lymphoma identifies 3q27 as a susceptibility locus in the Chinese population.


dbdate: 12/16/2013
author: Kapoor M
date: 06/07/2013
journal: Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23743675
trait: Alcohol consumption
initial_samplesize: 2,322 European ancestry individuals from 118 families, 2,593 European ancestry individuals
study:
A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.


dbdate: 01/09/2014
author: Randall JC
date: 06/06/2013
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23754948
trait: Sexual dimorphism in anthropometric traits
initial_samplesize: up to 60,586 Europrean ancestry men, up to 73,137 European ancestry women
replication_samplesize: up to 62,395 Europrean ancestry men, up to 74,657 European ancestry women
study:
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits.


dbdate: 12/06/2013
author: Yazar S
date: 06/06/2013
journal: Mol Vis
link: http://www.ncbi.nlm.nih.gov/pubmed/23761726
trait: Corneal astigmatism
initial_samplesize: 2,784 European ancestry individuals
study:
Interrogation of the platelet-derived growth factor receptor alpha locus and corneal astigmatism in Australians of Northern European ancestry: results of a genome-wide association study.


dbdate: 12/03/2013
author: Perera MA
date: 06/05/2013
journal: Lancet
link: http://www.ncbi.nlm.nih.gov/pubmed/23755828
trait: Warfarin maintenance dose
initial_samplesize: 533 African American individuals
replication_samplesize: 432 African American individuals
study:
Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study.


dbdate: 12/03/2013
author: Renteria ME
date: 06/03/2013
journal: Twin Res Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23725790
trait: DNA methylation (parent-of-origin)
initial_samplesize: 1,024 European ancestry individuals
study:
GWAS of DNA methylation variation within imprinting control regions suggests parent-of-origin association.


dbdate: 11/20/2013
author: Yang L
date: 05/31/2013
journal: Am J Med Genet B Neuropsychiatr Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23728934
trait: Attention deficit hyperactivity disorder
initial_samplesize: 1,040 Han Chinese ancestry cases, 963 Han Chinese ancestry controls
study:
Polygenic transmission and complex neuro developmental network for attention deficit hyperactivity disorder: genome-wide association study of both common and rare variants.


dbdate: 12/03/2013
author: Coram MA
date: 05/29/2013
journal: Am J Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23726366
trait: HDL cholesterol
initial_samplesize: 7,917 African American individuals, 3,506 Hispanic individuals
replication_samplesize: 7,138 African American individuals
study:
Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations.


dbdate: 11/14/2013
author: Xie P
date: 05/28/2013
journal: Biol Psychiatry
link: http://www.ncbi.nlm.nih.gov/pubmed/23726511
study: Genome-wide association study identifies new susceptibility loci for posttraumatic stress disorder.
trait: Post-traumatic stress disorder
initial_samplesize:
300 European ancestry cases, up to 1,538 European ancestry controls, 444 African American cases, up to 2,936 African American controls

replication_samplesize:
207 European ancestry cases, up to 1,692 European ancestry controls, 89 African American cases, up to 655 African American controls


dbdate: 11/20/2013
author: Cordell HJ
date: 05/26/2013
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23708191
trait: Congenital heart disease
study:
Genome-wide association study of multiple congenital heart disease phenotypes identifies a susceptibility locus for atrial septal defect at chromosome 4p16.

initial_samplesize:
1,479 European ancestry congenital heart disease cases, 340 European ancestry ostium secundum atrial septal defect cases, 5,159 European ancestry controls

replication_samplesize:
417 European ancestry ostium secundum atrial septal defect cases, 209 European ancestry ventricular septal defect cases, 2,520 European ancestry controls


dbdate: 11/15/2013
author: Hu Z
date: 05/26/2013
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23708190
trait: Congenital heart malformation
initial_samplesize: 945 Han Chinese ancestry cases, 1,246 Han Chinese ancestry controls
replication_samplesize: 2,160 Han Chinese ancestry cases, 3,866 Han Chinese ancestry controls
study:
A genome-wide association study identifies two risk loci for congenital heart malformations in Han Chinese populations.


dbdate: 11/15/2013
author: Kerns SL
date: 05/26/2013
journal: Radiother Oncol
link: http://www.ncbi.nlm.nih.gov/pubmed/23719583
trait: Adverse response to radiation therapy
study:
Genome-wide association study identifies a region on chromosome 11q14.3 associated with late rectal bleeding following radiation therapy for prostate cancer.

initial_samplesize:
79 European, African, Asian, and Hispanic ancestry cases, 241 European, African, Asian, and Hispanic ancestry controls

replication_samplesize:
107 European, African, Asian, and Hispanic ancestry cases, 671 European, African, Asian, and Hispanic ancestry controls


dbdate: 11/15/2013
author: Fatemifar G
date: 05/23/2013
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23704328
trait: Primary tooth development (number of teeth)
initial_samplesize: 11,513 European ancestry individuals
study:
Genome-wide association study of primary tooth eruption identifies pleiotropic loci associated with height and craniofacial distances.


dbdate: 11/13/2013
author: Ding K
date: 05/20/2013
journal: G3 (Bethesda)
link: http://www.ncbi.nlm.nih.gov/pubmed/23696099
trait: Red blood cell traits
initial_samplesize: 1904 African American individuals
replication_samplesize: 411 African American individuals
study:
Genetic variants that confer resistance to malaria are associated with red blood cell traits in African-Americans: an electronic medical record-based genome-wide association study.


dbdate: 11/14/2013
author: Kim JJ
date: 05/16/2013
journal: J Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23677057
trait: Coronary arterial lesions in patients with Kawasaki disease
initial_samplesize: 17 Korean ancestry cases, 123 Korean ancestry controls
replication_samplesize: 32 Korean ancestry cases, 191 Korean ancestry controls
study:
Identification of KCNN2 as a susceptibility locus for coronary artery aneurysms in Kawasaki disease using genome-wide association analysis.


dbdate: 11/03/2013
author: Graff M
date: 05/12/2013
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23669352
trait: Body mass index
initial_samplesize: Up to 13,627 European ancestry individuals
replication_samplesize: Up to 16,253 European ancestry individuals
study:
Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course.


dbdate: 09/27/2013
author: Kou I
date: 05/12/2013
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23666238
study: Genetic variants in GPR126 are associated with adolescent idiopathic scoliosis.
trait: Scoliosis
initial_samplesize: 1,033 Japanese ancestry cases, 1,473 Japanese ancestry controls
replication_samplesize:
786 Japanese ancestry cases, 24,466 Japanese ancestry controls, 743 Han Chinese ancestry cases, 1,209 Han Chinese ancestry controls, 447 European ancestry cases, 737 European ancestry controls


dbdate: 11/09/2013
author: Ruark E
date: 05/12/2013
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23666240
trait: Testicular germ cell tumor
initial_samplesize: 986 European ancestry cases, 4,946 European ancestry controls
replication_samplesize: 1,064 European ancestry cases, 10,082 European ancestry controls
study:
Identification of nine new susceptibility loci for testicular cancer, including variants near DAZL and PRDM14.


dbdate: 09/28/2013
author: Dubinsky MC
date: 05/09/2013
journal: Inflamm Bowel Dis
link: http://www.ncbi.nlm.nih.gov/pubmed/23665963
trait: Crohn's disease (need for surgery)
study:
Multidimensional prognostic risk assessment identifies association between IL12B variation and surgery in Crohn's disease.

initial_samplesize:
239 European ancestry cases that required surgery within 5 year, 375 European ancestry cases that did not require surgery within 5 years


dbdate: 09/21/2013
author: Tang W
date: 05/05/2013
journal: Genet Epidemiol
link: http://www.ncbi.nlm.nih.gov/pubmed/23650146
trait: Venous thromboembolism
initial_samplesize: 1,618 European ancestry cases, 42,881 European ancestry controls
replication_samplesize: 3,231 European ancestry cases, 3,536 European ancestry controls
study:
A genome-wide association study for venous thromboembolism: the extended cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium.


dbdate: 09/20/2013
author: Wu C
date: 05/05/2013
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23644492
trait: Esophageal squamous cell cancer (length of survival)
initial_samplesize: 1,331 Chinese ancestry cases
replication_samplesize: 1,062 Chinese ancestry individuals
study:
Genome-wide association study identifies common variants in SLC39A6 associated with length of survival in esophageal squamous-cell carcinoma.


dbdate: 11/14/2013
author: Low SK
date: 05/04/2013
journal: Cancer Sci
link: http://www.ncbi.nlm.nih.gov/pubmed/23648065
trait: Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)
initial_samplesize: 177 Japanese ancestry cases, 952 Japanese ancestry controls
study:
Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan.


dbdate: 09/21/2013
author: Cheong KA
date: 05/02/2013
journal: J Korean Med Sci
link: http://www.ncbi.nlm.nih.gov/pubmed/23678272
trait: Vitiligo (non-segmental)
initial_samplesize: 20 Korean ancestry cases, 192 Korean ancestry controls
replication_samplesize: 184 Korean ancestry cases, 192 Korean ancestry controls
study:
Three new single nucleotide polymorphisms identified by a genome-wide association study in Korean patients with vitiligo.


dbdate: 11/16/2013
author: Naj AC
date: 05/01/2013
journal: Ann Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23577725
trait: Age-related macular degeneration
initial_samplesize: 1,207 European ancestry cases, 686 European ancestry controls
replication_samplesize: 122 European ancestry cases, 86 European ancestry controls
study:
Genetic factors in nonsmokers with age-related macular degeneration revealed through genome-wide gene-environment interaction analysis.


dbdate: 09/18/2013
author: Tanaka T
date: 05/01/2013
journal: Am J Clin Nutr
link: http://www.ncbi.nlm.nih.gov/pubmed/23636237
trait: Dietary macronutrient intake
initial_samplesize: 37,537 European ancestry individuals
replication_samplesize: 33,533 European ancestry individuals
study:
Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake.


dbdate: 09/16/2013
author: Rinella ES
date: 04/30/2013
journal: J Clin Endocrinol Metab
link: http://www.ncbi.nlm.nih.gov/pubmed/23633212
trait: Weight loss (gastric bypass surgery)
initial_samplesize: 86 European ancestry individuals with least EBWL, 89 European ancestry individuals with most EBWL
replication_samplesize: 164 European ancestry individuals with least EBWL, 169 European ancestry individuals with most EBWL
study:
Genome-wide association of single-nucleotide polymorphisms with weight loss outcomes after Roux-en-Y gastric bypass surgery.


dbdate: 09/14/2013
author: Sulkava S
date: 04/29/2013
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23620144
trait: Job-related exhaustion
initial_samplesize: 1,256 European ancestry individuals
replication_samplesize: 13,864 European ancestry individuals
study:
Genome-wide scan of job-related exhaustion with three replication studies implicate a susceptibility variant at the UST gene locus.


dbdate: 09/14/2013
author: Zhao SX
date: 04/29/2013
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23612905
trait: Graves' disease
initial_samplesize: 1,442 Han Chinese ancestry cases, 1,468 Han Chinese ancestry controls
replication_samplesize: 7,891 Han Chinese ancestry cases, 8,351 Han Chinese ancestry controls
study:
Robust evidence for five new Graves' disease risk loci from a staged genome-wide association analysis.


dbdate: 09/12/2013
author: Deng M
date: 04/28/2013
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23624525
trait: Amyotrophic lateral sclerosis
initial_samplesize: 506 Han Chinese ancestry cases, 1,859 Han Chinese ancestry controls
replication_samplesize: 706 Han Chinese ancestry cases, 1,777 Han Chinese ancestry controls
study:
Genome-wide association analyses in Han Chinese identify two new susceptibility loci for amyotrophic lateral sclerosis.


dbdate: 09/10/2013
author: Reiner AP
date: 04/24/2013
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23620142
trait: Circulating myeloperoxidase levels (plasma)
initial_samplesize: 9,260 European ancestry individuals
study:
Genome-wide and gene-centric analyses of circulating myeloperoxidase levels in the charge and care consortia.


dbdate: 09/07/2013
author: Cox AJ
date: 04/19/2013
journal: Atherosclerosis
link: http://www.ncbi.nlm.nih.gov/pubmed/23642732
trait: Bilirubin levels
initial_samplesize: 1,180 European ancestry individuals from ~475 families
study:
Association of SNPs in the UGT1A gene cluster with total bilirubin and mortality in the Diabetes Heart Study.


dbdate: 08/06/2014
author: Noth I
date: 04/17/2013
journal: Lancet Respir Med
link: http://www.ncbi.nlm.nih.gov/pubmed/24429156
trait: Idiopathic pulmonary fibrosis
initial_samplesize: 542 European ancestry patients, 542 European ancestry controls
replication_samplesize: 868 European ancestry patients, 1,389 European ancestry controls
study:
Genetic variants associated with idiopathic pulmonary fibrosis susceptibility and mortality: a genome-wide association study.


dbdate: 08/23/2013
author: Monda KL
date: 04/14/2013
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23583978
trait: Body mass index
initial_samplesize: 37,956 African American individuals, 1,188 Nigerian ancestry individuals
study:
A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry.

replication_samplesize:
27,661 African America/Afro-Caribbean individuals, 4,607 Sub-Saharan African ancestry individuals, 123,706 European ancestry inidividuals


dbdate: 08/20/2013
author: den Hoed M
date: 04/14/2013
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23583979
trait: Heart rate
initial_samplesize: 85,787 European ancestry individuals, 6,568 Indian Asian ancestry indiviudals
replication_samplesize: 88,823 European ancestry individuals
study:
Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.


dbdate: 08/23/2013
author: Go MJ
date: 04/11/2013
journal: J Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23575436
trait: Glycemic traits
initial_samplesize: 7,696 Korean ancestry individuals
replication_samplesize: 6,536 Korean ancestry individuals
study:
New susceptibility loci in MYL2, C12orf51 and OAS1 associated with 1-h plasma glucose as predisposing risk factors for type 2 diabetes in the Korean population.


dbdate: 08/13/2013
author: Kirin M
date: 04/11/2013
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23585552
trait: Rhegmatogenous retinal detachment
initial_samplesize: 867 European ancestry cases, 1,953 European ancestry controls
replication_samplesize: 1,966 European ancestry cases, 5,918 European ancestry controls
study:
Genome-wide association study identifies genetic risk underlying primary rhegmatogenous retinal detachment.


dbdate: 08/24/2013
author: Reitz C
date: 04/10/2013
journal: JAMA
link: http://www.ncbi.nlm.nih.gov/pubmed/23571587
trait: Alzheimer's disease (late onset)
initial_samplesize: 1,968 African American cases, 3,928 African American controls
study:
Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E &#x003f5;4,and the risk of late-onset Alzheimer disease in African Americans.


dbdate: 08/17/2013
author: Urbanek M
date: 04/10/2013
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23575227
trait: Adiposity in newborns
replication_samplesize: 2,296 European ancestry individuals
study:
The chromosome 3q25 genomic region is associated with measures of adiposity in newborns in a multi-ethnic genome-wide association study.

initial_samplesize:
1,095 Afro-Caribbean ancestry individuals, 1,363 European ancestry individuals, 616 Mexican American individuals, 1,207 Thai ancestry individuals


dbdate: 08/07/2013
author: Zheng HF
date: 04/09/2013
journal: J Med Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23572186
trait: Bone mineral density
initial_samplesize: 5,866 European ancestry individuals
replication_samplesize: 715 Mexican American individuals
study:
Meta-analysis of genome-wide studies identifies MEF2C SNPs associated with bone mineral density at forearm.


dbdate: 09/12/2013
author: Berndt SI
date: 04/07/2013
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23563607
trait: Body mass index
study:
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.

initial_samplesize:
7,962 European ancestry individuals with high body mass index, 8,106 European ancestry individuals with low body mass index

replication_samplesize:
4,900 European ancestry individuals with high body mass index, 4,891 European ancestry individuals with low body mass index


dbdate: 10/24/2013
author: Wheeler E
date: 04/07/2013
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23563609
trait: Obesity (early onset extreme)
initial_samplesize: 1,509 European ancestry cases, 5,380 European ancestry controls
replication_samplesize: 971 European ancestry cases, 1,990 European ancestry controls
study:
Genome-wide SNP and CNV analysis identifies common and low-frequency variants associated with severe early-onset obesity.


dbdate: 09/24/2013
author: Ran S
date: 04/04/2013
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/23593202
trait: Femoral neck bone geometry and menarche (age at onset)
initial_samplesize: 1,728 European ancestry individuals
replication_samplesize: 501 European ancestry individuals, 826 Chinese ancestry individuals
study:
Bivariate genome-wide association analyses identified genes with pleiotropic effects for femoral neck bone geometry and age at menarche.


dbdate: 07/12/2013
author: Miyashita A
date: 04/02/2013
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/23565137
trait: Alzheimer's disease (late onset)
initial_samplesize: 891 Japanese ancestry cases, 844 Japanese ancestry controls
study:
SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians.

replication_samplesize:
1,224 East Asian ancestry cases, 2,114 East Asian ancestry controls, 11,840 European ancestry cases, 10,931 European ancestry controls


dbdate: 09/27/2013
author: Zhao L
date: 04/02/2013
journal: Ann Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23551011
trait: Preeclampsia
study:
Genome-Wide Association Study of Pre-Eclampsia Detects Novel Maternal Single Nucleotide Polymorphisms and Copy-Number Variants in Subsets of the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study Cohort.

initial_samplesize:
21 Afro-Caribbean ancestry cases, 1,010 Afro-Caribbean ancestry controls, 50 European ancestry cases, 1,202 European ancestry controls, 62 Hispanic cases, 658 Hispanic controls


dbdate: 09/27/2013
author: Ebejer JL
date: 04/01/2013
journal: Twin Res Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23527680
trait: Attention deficit hyperactivity disorder (combined symptoms)
initial_samplesize: 1,851 individuals
replication_samplesize: 155 individuals
study:
Genome-wide association study of inattention and hyperactivity-impulsivity measured as quantitative traits.


dbdate: 09/16/2013
author: Eeles RA
date: 04/01/2013
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23535732
trait: Prostate cancer
initial_samplesize: 11,085 European ancestry cases, 11,463 European ancestry controls
replication_samplesize: 19,662 European ancestry cases, 19,715 European ancestry controls
study:
Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array.


dbdate: 10/30/2013
author: Melen E
date: 04/01/2013
journal: Clin Exp Allergy
link: http://www.ncbi.nlm.nih.gov/pubmed/23517042
study: Genome-wide association study of body mass index in 23 000 individuals with and without asthma.
trait: Body mass index (asthmatics)
replication_samplesize: 979 European ancestry children, 921 Hispanic children, 120 Other ancestry children
initial_samplesize:
1,881 European ancestry children, 109 European and other ancestry children, 701 Other ancestry children


dbdate: 07/12/2013
author: Pharoah PD
date: 04/01/2013
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23535730
study: GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer.
trait: Ovarian cancer
initial_samplesize: 3,769 European ancestry cases, 4,396 European ancestry controls
replication_samplesize:
211 East Asian cases, 972 East Asian controls, 39,674 European ancestry individuals, 106 Malaysian cases, 106 Malaysian controls


dbdate: 07/27/2013
author: Yang SK
date: 04/01/2013
journal: Inflamm Bowel Dis
link: http://www.ncbi.nlm.nih.gov/pubmed/23511034
trait: Ulcerative colitis
initial_samplesize: 388 Korean ancestry cases, 739 Korean ancestry controls
replication_samplesize: 810 Korean ancestry cases, 1709 Korean ancestry controls
study:
Genome-wide association study of ulcerative colitis in Koreans suggests extensive overlapping of genetic susceptibility with Caucasians.


dbdate: 08/10/2013
author: Zhang M
date: 04/01/2013
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23548203
trait: Eye color
initial_samplesize: 3871 European ancestry individuals
replication_samplesize: 2,496 European ancestry individuals
study:
Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans.


dbdate: 07/25/2013
author: Cui J
date: 03/28/2013
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23555300
trait: Response to anti-TNF treatment in rheumatoid arthritis
initial_samplesize: Up to 2,706 European ancestry cases
study:
Genome-wide association study and gene expression analysis identifies CD84 as a predictor of response to etanercept therapy in rheumatoid arthritis.


dbdate: 07/31/2013
author: Jeff JM
date: 03/28/2013
journal: Ann Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23534349
trait: Heart rate
initial_samplesize: 455 African American individuals
study:
Generalization of variants identified by genome-wide association studies for electrocardiographic traits in african americans.


dbdate: 07/05/2013
author: Kitamoto T
date: 03/28/2013
journal: Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23535911
trait: Non-alcoholic fatty liver disease
initial_samplesize: 392 Japanese ancestry cases, 934 Japanese ancestry controls
replication_samplesize: 172 Japanese ancestry cases, 1,012 Japanese ancestry controls
study:
Genome-wide scan revealed that polymorphisms in the PNPLA3, SAMM50, and PARVB genes are associated with development and progression of nonalcoholic fatty liver disease in Japan.


dbdate: 07/05/2013
author: Tin A
date: 03/28/2013
journal: J Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23535967
trait: Glomerular filtration rate
initial_samplesize: 9,049 European ancestry individuals
study:
Using multiple measures for quantitative trait association analyses: application to estimated glomerular filtration rate.


dbdate: 08/02/2013
author: Couch FJ
date: 03/27/2013
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23544013
trait: Breast Cancer in BRCA1 mutation carriers
initial_samplesize: 1,426 European ancestry cases, 1,301 European ancestry controls
replication_samplesize: 6,031 European ancestry cases, 5,933 European ancestry controls
study:
Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk.


dbdate: 06/27/2013
author: Li X
date: 03/27/2013
journal: J Allergy Clin Immunol
link: http://www.ncbi.nlm.nih.gov/pubmed/23541324
trait: Pulmonary function in asthmatics
initial_samplesize: 1,544 European ancestry individuals
study:
Genome-wide association study identifies TH1 pathway genes associated with lung function in asthmatic patients.


dbdate: 06/26/2013
author: Ma RC
date: 03/27/2013
journal: Diabetologia
link: http://www.ncbi.nlm.nih.gov/pubmed/23532257
trait: Type 2 diabetes
initial_samplesize: 684 Han Chinese ancestry cases, 955 Han Chinese ancestry controls
study:
Genome-wide association study in a Chinese population identifies a susceptibility locus for type 2 diabetes at 7q32 near PAX4.

replication_samplesize:
18,954 East Asian ancestry cases, 18,029 East Asian ancestry controls, 794 Singaporean Malay ancestry cases, 1,204 Singaporean Malay ancestry controls, 977 Singaporean Indian ancestry cases, 1,169 Singaporean Indian ancestry controls, 8,130 European ancestry cases, 38,987 European ancestry controls


dbdate: 06/26/2013
author: Liu M
date: 03/21/2013
journal: Mol Endocrinol
link: http://www.ncbi.nlm.nih.gov/pubmed/23518928
study: TSPYL5 SNPs: association with plasma estradiol concentrations and aromatase expression.
trait: Estradiol plasma levels (breast cancer)
initial_samplesize:
700 European ancestry cases, 50 African ancestry cases, 17 Asian ancestry cases, 5 American Indian cases


dbdate: 07/26/2013
author: Xu H
date: 03/19/2013
journal: J Natl Cancer Inst
link: http://www.ncbi.nlm.nih.gov/pubmed/23512250
trait: Acute lymphoblastic leukemia (childhood)
study:
Novel susceptibility variants at 10p12.31-12.2 for childhood acute lymphoblastic leukemia in ethnically diverse populations.

initial_samplesize:
972 European ancestry cases, 1,386 European ancestry controls, 89 African American cases, 1,363 African American controls, 305 Hispanic cases, 1,008 Hispanic controls

replication_samplesize:
574 European ancestry cases, 2,601 European ancestry controls, 128 African American cases, 1,075 African American controls, 143 Hispanic cases, 640 Hispanic controls


dbdate: 06/20/2013
author: Luca G
date: 03/18/2013
journal: J Sleep Res
link: http://www.ncbi.nlm.nih.gov/pubmed/23496005
trait: Narcolepsy with cataplexy
initial_samplesize: 585 European ancestry cases
replication_samplesize: 387 European ancestry cases
study:
Clinical, polysomnographic and genome-wide association analyses of narcolepsy with cataplexy: a European Narcolepsy Network study.


dbdate: 07/01/2013
author: Zhou G
date: 03/18/2013
journal: J Biol Chem
link: http://www.ncbi.nlm.nih.gov/pubmed/23508960
trait: Aspirin hydrolysis (plasma)
initial_samplesize: 2,054 European ancestry individuals
study:
Aspirin hydrolysis in plasma is a variable function of butyrylcholinesterase and platelet-activating factor acetylhydrolase 1b2 (PAFAH1b2).


dbdate: 06/21/2013
author: Germain M
date: 03/17/2013
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23502781
trait: Pulmonary arterial hypertension (without BMPR2 mutations)
initial_samplesize: 340 European ancestry cases, 1,068 European ancestry controls
replication_samplesize: 285 cases, 457 controls
study:
Genome-wide association analysis identifies a susceptibility locus for pulmonary arterial hypertension.


dbdate: 06/18/2013
author: van Setten J
date: 03/13/2013
journal: Atherosclerosis
link: http://www.ncbi.nlm.nih.gov/pubmed/23561647
trait: Coronary artery calcification
initial_samplesize: 2,620 European ancestry males
study:
Genome-wide association study of coronary and aortic calcification implicates risk loci for coronary artery disease and myocardial infarction.


dbdate: 07/01/2013
author: Han JY
date: 03/12/2013
journal: Pharmacogenomics J
link: http://www.ncbi.nlm.nih.gov/pubmed/23478653
trait: Response to irinotecan and platinum-based chemotherapy in non-small-cell lung cancer
initial_samplesize: 139 individuals
study:
A genome-wide association study of survival in small-cell lung cancer patients treated with irinotecan plus cisplatin chemotherapy.


dbdate: 06/16/2013
author: Stambolian D
date: 03/07/2013
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23474815
trait: Refractive error
initial_samplesize: 6,597 European ancestry individuals, 683 Sardinian inidividuals
replication_samplesize: 19,763 European ancestry individuals
study:
Meta-analysis of genome-wide association studies in five cohorts reveals common variants in RBFOX1, a regulator of tissue-specific splicing, associated with refractive error.


dbdate: 06/21/2013
author: Zeng Z
date: 03/07/2013
journal: J Dent Res
link: http://www.ncbi.nlm.nih.gov/pubmed/23470693
trait: Pit-and-Fissure caries
initial_samplesize: 996 European ancestry individuals
study:
Genome-wide association studies of pit-and-fissure- and smooth-surface caries in permanent dentition.


dbdate: 06/28/2013
author: Pare G
date: 03/06/2013
journal: Circulation
link: http://www.ncbi.nlm.nih.gov/pubmed/23467860
study: Genetic determinants of dabigatran plasma levels and their relation to bleeding.
trait: Response to dabigatran etexilate treatment
initial_samplesize: 1,490 European ancestry atrial fibrillation patients at risk of stroke
replication_samplesize:
204 European ancestry atrial fibrillation patients at risk of stroke, 66 Latin American ancestry atrial fibrillation patients at risk of stroke, 1 Arab ancestry atrial fibrillation patient at risk of stroke, 5 Black African atrial fibrillation patients at risk of stroke, 21 Chinese ancestry atrial fibrillation patients at risk of stroke, 1 Colored African atrial fibrillation patient at risk of stroke, 4 Japanese ancestry atrial fibrillation patients at risk of stroke, 9 South Asian ancestry atrial fibrillation patients at risk of stroke, 15 other Asian ancestry atrial fibrillation patients at risk of stroke and 134 atrial fibrillation patients at risk of stroke


dbdate: 06/14/2013
author: Avery CL
date: 03/05/2013
journal: Pharmacogenomics J
link: http://www.ncbi.nlm.nih.gov/pubmed/23459443
trait: QT interval (interaction)
initial_samplesize: 33,781 Euroepan ancestry individuals
study:
Drug-gene interactions and the search for missing heritability: a cross-sectional pharmacogenomics study of the QT interval.


dbdate: 06/18/2013
author: Jahanshad N
date: 03/05/2013
journal: Proc Natl Acad Sci U S A
link: http://www.ncbi.nlm.nih.gov/pubmed/23471985
trait: Brain connectivity
initial_samplesize: 331 European ancestry individuals
study:
Genome-wide scan of healthy human connectome discovers SPON1 gene variant influencing dementia severity.


dbdate: 06/13/2013
author: Mero IL
date: 03/05/2013
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/23472185
trait: Multiple sclerosis (OCB status)
initial_samplesize: 1,367 European ancestry OCB positive cases, 161 European ancestry OCB negative cases
replication_samplesize: 3,029 European ancestry OCB positive cases, 374 European ancestry OCB negative cases
study:
Oligoclonal band status in Scandinavian multiple sclerosis patients is associated with specific genetic risk alleles.


dbdate: 04/11/2013
author: Crosslin DR
date: 03/03/2013
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23314186
study: Genetic variation associated with circulating monocyte count in the eMERGE Network.
trait: Monocyte count
initial_samplesize:
9,849 European ancestry individuals, 894 African ancestry individuals, 271 other ancestry individuals


dbdate: 07/31/2013
author: Fritsche LG
date: 03/03/2013
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23455636
study: Seven new loci associated with age-related macular degeneration.
trait: Age-related macular degeneration
initial_samplesize:
6,713 European ancestry cases, 48,402 European ancestry contols, 110 Southern Indian ancestry cases, 119 Southern Indian ancestry controls, 827 Japanese ancestry cases, 3,323 Japanese ancestry controls

replication_samplesize:
9,070 European ancestry cases, 7,683 European ancestry contols, 461 East Asian ancestry cases, 547 East Asian ancestry controls


dbdate: 06/18/2013
author: Park BL
date: 03/01/2013
journal: Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23456092
trait: Alcohol dependence
initial_samplesize: 117 Korean ancestry cases, 279 Korean ancestry controls
replication_samplesize: 504 Korean ancestry cases, 471 Korean ancestry controls
study:
Extended genetic effects of ADH cluster genes on the risk of alcohol dependence: from GWAS to replication.


dbdate: 05/30/2013
author: Liu Z
date: 02/28/2013
journal: ScientificWorldJournal
link: http://www.ncbi.nlm.nih.gov/pubmed/23533358
study: NCK2 is significantly associated with opiates addiction in African-origin men.
trait: Addiction
initial_samplesize:
1,393 European ancestry women, 1,131 European ancestry men, 568 African ancestry women, 535 African ancestry men


dbdate: 05/26/2013
author: Shi Y
date: 02/28/2013
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23406873
trait: Myopia (pathological)
initial_samplesize: 665 Han Chinese ancestry cases, 960 Han Chinese ancestry controls
replication_samplesize: 2,128 Han Chinese ancestry cases, 3,683 Han Chinese ancestry controls
study:
A genome-wide meta-analysis identifies two novel loci associated with high myopia in the Han Chinese population.


dbdate: 05/31/2013
author: Cousminer DL
date: 02/27/2013
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23449627
trait: Pubertal anthropometrics
initial_samplesize: 7,161 European ancestry males, 6,879 European ancestry females
replication_samplesize: 5,133 European ancestry males, 4,577 European ancestry females
study:
Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.


dbdate: 06/06/2013
author: Smoller JW
date: 02/27/2013
journal: Lancet
link: http://www.ncbi.nlm.nih.gov/pubmed/23453885
study:
Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.

trait:
Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined)

initial_samplesize:
6,990 European ancestry Bipolar disorder cases, 9,227 European ancestry Major depressive disorder cases, 9,379 European ancestry Schizophrenia cases, 161 European ancestry Autism spectrum disorder cases, 4,788 European ancestry Autism spectrum disorder trio cases, 840 European ancestry Attention deficit-hyperactivity disorder cases, 1,947 European ancestry Attention defcit-hyperactivity disorder trio cases, 27,888 European ancestry controls


dbdate: 05/26/2013
author: Zuo L
date: 02/27/2013
journal: Drug Alcohol Depend
link: http://www.ncbi.nlm.nih.gov/pubmed/23455491
trait: Alcohol dependence
initial_samplesize: 1,409 European ancestry cases, 1,518 European ancestry controls
replication_samplesize: 6,438 European ancestry individuals from 1,645 affected families
study:
NKAIN1-SERINC2 is a functional, replicable and genome-wide significant risk gene region specific for alcohol dependence in subjects of European descent.


dbdate: 06/28/2013
author: Chen Z
date: 02/26/2013
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23446634
study: Genome-wide association analysis of red blood cell traits in African Americans: the COGENT Network.
trait: Red blood cell traits
initial_samplesize: Up to 16,485 African American individuals
replication_samplesize:
9,692 African American individuals, 21,020 European ancestry individuals, 14,088 Japanese ancestry individuals


dbdate: 05/26/2013
author: Kamboh MI
date: 02/24/2013
journal: Autoimmune Dis
link: http://www.ncbi.nlm.nih.gov/pubmed/23509613
study: Genome-wide association study of antiphospholipid antibodies.
trait: Presence of antiphospholipid antibodies
initial_samplesize:
183 European ancestry ACL-positive cases, 487 European ancestry ACL-negative controls, 127 European ancestry LAC-positive cases, 581 European ancestry LAC-negative controls, 136 European ancestry Anti-B2GPI-positive cases, 360 European ancestry Anti-B2GPI-negative controls


dbdate: 05/21/2013
author: Paternoster L
date: 02/21/2013
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23437003
trait: Bone mineral density
initial_samplesize: up to 5,878 European ancestry individuals
replication_samplesize: up to 1,052 European ancestry individuals
study:
Genetic determinants of trabecular and cortical volumetric bone mineral densities and bone microstructure.


dbdate: 06/06/2013
author: Duggal P
date: 02/19/2013
journal: Ann Intern Med
link: http://www.ncbi.nlm.nih.gov/pubmed/23420232
trait: Chronic hepatitis C infection
initial_samplesize: 1,482 chronic HCV patients, 919 spontaneously cleared HCV patients
replication_samplesize: 461 chronic HCV patients, 284 spontaneously cleared HCV patients
study:
Genome-wide association study of spontaneous resolution of hepatitis C virus infection: data from multiple cohorts.


dbdate: 05/17/2013
author: Ludwig KU
date: 02/19/2013
journal: Transl Psychiatry
link: http://www.ncbi.nlm.nih.gov/pubmed/23423138
trait: Mathematical ability in children with dyslexia
initial_samplesize: 200 European ancestry cases
replication_samplesize: 510 European ancestry cases
study:
A common variant in myosin-18B contributes to mathematical abilities in children with dyslexia and intraparietal sulcus variability in adults.


dbdate: 06/06/2013
author: Ramanan VK
date: 02/19/2013
journal: Mol Psychiatry
link: http://www.ncbi.nlm.nih.gov/pubmed/23419831
trait: Alzheimer's disease biomarkers
initial_samplesize: 555 European ancestry individuals
study:
APOE and BCHE as modulators of cerebral amyloid deposition: a florbetapir PET genome-wide association study.


dbdate: 08/21/2013
author: Thanassoulis G
date: 02/17/2013
journal: N Engl J Med
link: http://www.ncbi.nlm.nih.gov/pubmed/23388002
study: Genetic associations with valvular calcification and aortic stenosis.
trait: Aortic-valve calcification
initial_samplesize: 6,942 European ancestry individuals
replication_samplesize:
745 European ancestry individuals, 2,497 African American individuals, 2,027 Hispanic individuals, 774 Chinese ancestry individuals


dbdate: 06/06/2013
author: Tin A
date: 02/16/2013
journal: Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23417110
trait: Beta-2 microglubulin plasma levels
initial_samplesize: 6,728 European ancestry individuals
study:
Genome-wide association study identified the human leukocyte antigen region as a novel locus for plasma beta-2 microglobulin.


dbdate: 05/11/2013
author: Del-Aguila JL
date: 02/12/2013
journal: Pharmacogenomics J
link: http://www.ncbi.nlm.nih.gov/pubmed/23400010
trait: Thiazide-induced adverse metabolic effects in hypertensive patients
initial_samplesize: 425 European ancestry cases, 342 African American cases
study:
Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans.


dbdate: 06/06/2013
author: Verhoeven VJ
date: 02/10/2013
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23396134
trait: Refractive error
study:
Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia.

initial_samplesize:
37,382 European ancestry individuals, 578 Han Chinese ancestry individuals, 3,417 Singaporean Chinese ancestry individuals, 2,273 Singaporean Malay ancestry individuals, 2,108 Singaporean Indian ancestry individuals


dbdate: 05/14/2013
author: Porcu E
date: 02/07/2013
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23408906
trait: Thyroid hormone levels
study:
A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function.

initial_samplesize:
up to 12,289 European ancestry females, up to 9,019 European ancestry males, up to 433 Old Order Amish females, up to 592 Old Order Amish males, 2,170 Sardinian females, 1,917 Sardinian males


dbdate: 05/09/2013
author: Verweij N
date: 02/04/2013
journal: Hypertension
link: http://www.ncbi.nlm.nih.gov/pubmed/23381795
trait: Circulating vasoactive peptide levels
initial_samplesize: 3,444 Euorpean ancestry individuals
replication_samplesize: 3,230 European ancestry individuals
study:
Genome-wide association study on plasma levels of midregional-proadrenomedullin and C-terminal-pro-endothelin-1.


dbdate: 05/08/2013
author: Aberg KA
date: 02/01/2013
journal: JAMA Psychiatry
link: http://www.ncbi.nlm.nih.gov/pubmed/23894747
study: A comprehensive family-based replication study of schizophrenia genes.
trait: Schizophrenia
initial_samplesize: 11,185 European ancestry cases, 10,768 European ancestry controls
replication_samplesize:
1,262 African American ancestry individuals, 2,740 European ancestry individuals, 2,296 Asian ancestry individuals


dbdate: 05/09/2013
author: GENDEP Investigators
date: 02/01/2013
journal: Am J Psychiatry
link: http://www.ncbi.nlm.nih.gov/pubmed/23377640
trait: Major depressive disorder
initial_samplesize: Up to 2,256 European ancestry cases
study:
Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.


dbdate: 05/09/2013
author: Xie W
date: 02/01/2013
journal: Diabetes
link: http://www.ncbi.nlm.nih.gov/pubmed/23378610
trait: Metabolite levels
initial_samplesize: 1,004 European ancestry individuals
replication_samplesize: 339 European ancestry individuals
study:
Genetic variants associated with glycine metabolism and their role in insulin sensitivity and type 2 diabetes.


dbdate: 05/09/2013
author: Dai X
date: 01/31/2013
journal: Genet Epidemiol
link: http://www.ncbi.nlm.nih.gov/pubmed/23371916
trait: Bilirubin levels
initial_samplesize: 1,452 Han Chinese ancestry individuals
replication_samplesize: 8,830 Han Chinese ancestry individuals
study:
A genome-wide association study for serum bilirubin levels and gene-environment interaction in a Chinese population.


dbdate: 05/09/2013
author: Kerns SL
date: 01/31/2013
journal: J Urol
link: http://www.ncbi.nlm.nih.gov/pubmed/23376709
trait: Urinary symptoms in response to radiotherapy in prostate cancer
initial_samplesize: 346 European, African, Hispanic and Asian ancestry individuals
replication_samplesize: 377 European, African, Hispanic and Asian ancestry individuals
study:
A 2-stage genome-wide association study to identify single nucleotide polymorphisms associated with development of urinary symptoms after radiotherapy for prostate cancer.


dbdate: 06/14/2013
author: Lauc G
date: 01/31/2013
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23382691
trait: IgG glycosylation
initial_samplesize: 1,848 European ancestry individuals
study:
Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.


dbdate: 05/02/2013
author: Borglum AD
date: 01/29/2013
journal: Mol Psychiatry
link: http://www.ncbi.nlm.nih.gov/pubmed/23358160
trait: Schizophrenia
initial_samplesize: 888 European ancestry cases, 882 European ancestry controls
replication_samplesize: 2539 European ancestry cases, 5486 European ancestry controls
study:
Genome-wide study of association and interaction with maternal cytomegalovirus infection suggests new schizophrenia loci.


dbdate: 05/02/2013
author: Martinelli-Boneschi F
date: 01/29/2013
journal: Neurobiol Aging
link: http://www.ncbi.nlm.nih.gov/pubmed/23374588
trait: Response to cholinesterase inhibitors in Alzheimer's disease
initial_samplesize: 92 European ancestry cases, 77 European ancestry controls
replication_samplesize: 94 European ancestry cases, 74 European ancestry controls
study:
Pharmacogenomics in Alzheimer's disease: a genome-wide association study of response to cholinesterase inhibitors.


dbdate: 06/05/2013
author: Wu JH
date: 01/29/2013
journal: Circ Cardiovasc Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23362303
trait: Oleic acid (18:1n-9) plasma levels
initial_samplesize: 8,961 European ancestry individuals
study:
Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.


dbdate: 05/01/2013
author: Xu C
date: 01/29/2013
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/23382809
trait: Schizophrenia (negative symptoms)
initial_samplesize: 1,774 European ancestry cases, 2,726 European ancestry controls
study:
BCL9 and C9orf5 are associated with negative symptoms in schizophrenia: meta-analysis of two genome-wide association studies.


dbdate: 04/23/2013
author: Fernandez-Rozadilla C
date: 01/26/2013
journal: BMC Genomics
link: http://www.ncbi.nlm.nih.gov/pubmed/23350875
trait: Colorectal cancer
initial_samplesize: 882 European ancestry cases, 473 European ancestry controls
replication_samplesize: 1,436 European ancestry cases, 1,780 European ancestry controls
study:
A colorectal cancer genome-wide association study in a Spanish cohort identifies two variants associated with colorectal cancer risk at 1p33 and 8p12.


dbdate: 04/24/2013
author: Rinella ES
date: 01/25/2013
journal: Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23354978
trait: Breast cancer
initial_samplesize: 477 Ashkenazi Jewish cases, 524 Ashkenazi Jewish controls
replication_samplesize: 203 Ashkenazi Jewish cases, 263 Ashkenazi Jewish contols
study:
Genetic variants associated with breast cancer risk for Ashkenazi Jewish women with strong family histories but no identifiable BRCA1/2 mutation.


dbdate: 04/17/2013
author: Dong J
date: 01/17/2013
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23341777
trait: Squamous cell carcinoma
initial_samplesize: 833 Han Chinese ancestry cases, 3,094 Han Chinese ancestry controls
replication_samplesize: 2,223 Han Chinese ancestry cases, 6,409 Han Chinese ancestry controls
study:
Genome-wide association study identifies a novel susceptibility locus at 12q23.1 for lung squamous cell carcinoma in han chinese.


dbdate: 04/17/2013
author: Vijai J
date: 01/17/2013
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23349640
study: Susceptibility loci associated with specific and shared subtypes of lymphoid malignancies.
trait: Lymphoma
initial_samplesize:
275 Follicular non-Hodgkin�s Lymphoma cases, 269 diffuse large B-cell non-Hodgkin�s Lymphoma cases, 198 other non-Hodgkin�s Lymphoma cases, 202 Hodgkin�s Lymphoma cases, 4,044 controls

replication_samplesize:
202 European ancestry Follicular non-Hodgkin�s Lymphoma cases, 367 European ancestry diffuse large B-cell non-Hodgkin�s Lymphoma cases, 577 European ancestry other non-Hodgkin�s Lymphoma cases, 99 European ancestry Hodgkin�s Lymphoma cases, 2,596 European ancestry controls


dbdate: 04/04/2013
author: Tin A
date: 01/16/2013
journal: Nephrol Dial Transplant
link: http://www.ncbi.nlm.nih.gov/pubmed/23328707
trait: Beta-trace protein levels
initial_samplesize: 6,720 European ancestry individuals
replication_samplesize: 1,734 African American individuals
study:
Genome-wide significant locus of beta-trace protein, a novel kidney function biomarker, identified in European and African Americans.


dbdate: 03/26/2013
author: Urabe Y
date: 01/12/2013
journal: J Hepatol
link: http://www.ncbi.nlm.nih.gov/pubmed/23321320
trait: Hepatitis C induced liver cirrhosis
initial_samplesize: 682 Japanese ancestry cases, 1,045 Japanese ancestry controls
replication_samplesize: 936 Japanese ancestry cases, 3,809 Japanese ancestry controls
study:
A genome-wide association study of HCV-induced liver cirrhosis in the Japanese population identifies novel susceptibility loci at the MHC region.


dbdate: 04/19/2013
author: Holliday EG
date: 01/11/2013
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/23326517
trait: Age-related macular degeneration
initial_samplesize: 3,772 European ancestry cases, 16,033 European ancestry controls
replication_samplesize: 264 Asian ancestry cases, 3,926 Asian ancestry controls
study:
Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.


dbdate: 04/12/2013
author: Greenwood TA
date: 01/10/2013
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/23326512
trait: Bipolar disorder (mania)
replication_samplesize: 121 European ancestry Irritable maniacases, 1026 European ancestry Elated mania cases
study:
Genome-wide association study of irritable vs. elated mania suggests genetic differences between clinical subtypes of bipolar disorder.

initial_samplesize:
117 European ancestry Irritable mania cases, 843 European ancestry Elated mania cases, 1033 European ancestry controls


dbdate: 05/01/2013
author: Rubicz R
date: 01/10/2013
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23326239
trait: Epstein-Barr virus immune response (EBNA-1)
initial_samplesize: 1,367 Mexican American indivduals
replication_samplesize: 589 Mexican American indivduals
study:
A genome-wide integrative genomic study localizes genetic factors influencing antibodies against Epstein-Barr virus nuclear antigen 1 (EBNA-1).


dbdate: 03/27/2013
author: Saxena R
date: 01/08/2013
journal: Diabetes
link: http://www.ncbi.nlm.nih.gov/pubmed/23300278
trait: Type 2 diabetes
initial_samplesize: 842 Punjabi Sikh cases, 774 Punjabi Sikh controls
study:
Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.

replication_samplesize:
up to 2,512 Punjabi Sikh cases and 3,201 Punjabi Sikh controls; up to 16,128 South Asian cases and 23,846 South Asian controls; up to 16,746 East Asian ancestry cases and 16,961 East Asian ancestry controls; up to 8,130 European ancestry cases and 38,987 European ancestry controls


dbdate: 04/17/2013
author: Cordell HJ
date: 01/07/2013
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23297363
trait: Tetralogy of Fallot
initial_samplesize: 835 European ancestry cases, 5,159 European ancestry controls
replication_samplesize: 798 European ancestry cases and 2,931 European ancestry controls
study:
Genome-wide association study identifies loci on 12q24 and 13q32 associated with tetralogy of Fallot.


dbdate: 04/11/2013
author: He M
date: 01/07/2013
journal: Gut
link: http://www.ncbi.nlm.nih.gov/pubmed/23300138
trait: Tumor biomarkers
initial_samplesize: 3,451 Han Chinese ancestry individuals
replication_samplesize: 10,326 Chinese ancestry individuals
study:
A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and &#x003b1; fetoprotein and their associations with cancer risk.


dbdate: 03/21/2013
author: Donnelly
date: 01/06/2013
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23291585
trait: Leishmaniasis (visceral)
replication_samplesize: 889 Indian ancestry cases, 948 Indian ancestry controls.
study:
Common variants in the HLA-DRB1-HLA-DQA1 HLA class II region are associated with susceptibility to visceral leishmaniasis.

initial_samplesize:
889 Indian ancestry cases, 977 Indian ancestry controls, 357 Brazilian ancestry cases, and 1,615 Brazilian ancestry unaffected relatives


dbdate: 03/27/2013
author: Kirino Y
date: 01/06/2013
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23291587
trait: Behcet's disease
initial_samplesize: 435 Turkish cases with uveitis, 780 Turkish cases without uveitis, 1,278 Turkish controls
study:
Genome-wide association analysis identifies new susceptibility loci for Beh&#x000e7;et's disease and epistasis between HLA-B*51 and ERAP1.

replication_samplesize:
355 Turkish cases with uveitis, 483 Turkish cases without uveitis, 601 Turkish controls, up to 612 Japanese ancestry cases, up to 740 Japanese ancestry controls


dbdate: 03/28/2013
author: Lu Y
date: 01/06/2013
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23291589
trait: Corneal structure
study:
Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.

initial_samplesize:
13,057 European ancestry individuals, 2,538 Indian ancestry individuals, 2,542 Malay ancestry individuals, 1,883 Chinese ancestry individuals


dbdate: 03/20/2013
author: Guggenheim JA
date: 01/03/2013
journal: Mol Vis
link: http://www.ncbi.nlm.nih.gov/pubmed/23401653
trait: Corneal curvature
initial_samplesize: 2,023 European ancestry children
study:
A genome-wide association study for corneal curvature identifies the platelet-derived growth factor receptor &#x003b1; gene as a quantitative trait locus for eye size in white Europeans.

replication_samplesize:
2,008 Chinese ancestry adults, 2,281 Malay ancestry adults, 2,142 Indian ancestry adults, 929 Chinese ancestry children


dbdate: 03/19/2013
author: Athanasiadis G
date: 01/02/2013
journal: J Thromb Haemost
link: http://www.ncbi.nlm.nih.gov/pubmed/23279374
trait: &beta;2-Glycoprotein I (&beta;2-GPI) plasma levels
initial_samplesize: 306 European ancestry individuals
study:
Genetic determinants of plasma &#x003b2;&#x02082;-glycoprotein I levels: a genome-wide association study in extended pedigrees from Spain.


dbdate: 06/18/2013
author: Li WD
date: 01/02/2013
journal: Obesity (Silver Spring)
link: http://www.ncbi.nlm.nih.gov/pubmed/23703922
trait: Uric acid levels
initial_samplesize: 487 European ancestry obese individuals, 472 non-obese individuals
study:
A genome wide association study of plasma uric acid levels in obese cases and never-overweight controls.


dbdate: 03/27/2013
author: Jin G
date: 01/01/2013
journal: Neoplasia
link: http://www.ncbi.nlm.nih.gov/pubmed/23359319
trait: Prostate-specific antigen levels
initial_samplesize: 3,192 European ancestry individuals
replication_samplesize: 1,722 European ancestry individuals
study:
Genome-wide association study identifies loci at ATF7IP and KLK2 associated with percentage of circulating free PSA.


dbdate: 03/22/2013
author: Sun J
date: 12/27/2012
journal: Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23269536
trait: Prostate-specific antigen levels
initial_samplesize: 1,999 Chinese ancestry males
replication_samplesize: 1,496 Chinese ancestry males
study:
Genome-wide association study identified novel genetic variant on SLC45A3 gene associated with serum levels prostate-specific antigen (PSA) in a Chinese population.


dbdate: 02/21/2013
author: Yang W
date: 12/27/2012
journal: Am J Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23273568
trait: Systemic lupus erythematosus
initial_samplesize: 1,656 Han Chinese ancestry cases, 3,394 Han Chinese ancestry controls
study:
Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.

replication_samplesize:
3,256 Han Chinese ancestry cases, 5,667 Han Chinese ancestry controls, 453 Thai ancestry cases, 963 Thai ancestry controls


dbdate: 02/21/2013
author: Desch KC
date: 12/24/2012
journal: Proc Natl Acad Sci U S A
link: http://www.ncbi.nlm.nih.gov/pubmed/23267103
trait: Coagulation factor levels
initial_samplesize: 3,250 European ancestry individuals, up to 212 individuals
study:
Linkage analysis identifies a locus for plasma von Willebrand factor undetected by genome-wide association.


dbdate: 03/05/2013
author: Jia WH
date: 12/23/2012
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23263487
trait: Colorectal cancer
initial_samplesize: 2,098 East Asian ancestry cases, 5,749 East Asian ancestry controls
study:
Genome-wide association analyses in East Asians identify new susceptibility loci for colorectal cancer.

replication_samplesize:
5,358 East Asian ancestry cases, 5,922 East Asian ancestry controls, 26,060 European ancestry individuals


dbdate: 02/19/2013
author: Peters U
date: 12/21/2012
journal: Gastroenterology
link: http://www.ncbi.nlm.nih.gov/pubmed/23266556
study: Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis.
trait: Colorectal cancer
initial_samplesize: 12,696 European ancestry colorectal tumor cases, and 15,113 European ancestry controls
replication_samplesize:
958 European ancestry colorectal tumor cases, up to 2,098 East Asian ancestry colorectal tumor cases, 909 European ancestry controls, up to 5,749 East Asian ancestry controls


dbdate: 02/26/2013
author: Wang X
date: 12/21/2012
journal: BMC Oral Health
link: http://www.ncbi.nlm.nih.gov/pubmed/23259602
study: Genome-wide association scan of dental caries in the permanent dentition.
trait: Dental caries
initial_samplesize:
1,483 comparatively younger European ancestry individuals, 5,960 comparatively older European ancestry individuals


dbdate: 02/27/2013
author: Yamazaki K
date: 12/21/2012
journal: Gastroenterology
link: http://www.ncbi.nlm.nih.gov/pubmed/23266558
trait: Crohn's disease
initial_samplesize: 372 Japanese ancestry cases and 3,389 Japanese ancestry controls
replication_samplesize: Up to 1,151 Japanese ancestry cases and up to 15,800 Japanese ancestry controls
study:
A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population.


dbdate: 02/27/2013
author: Hancock DB
date: 12/20/2012
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23284291
trait: Pulmonary function (interaction)
initial_samplesize: 50,047 European ancestry individuals
study:
Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function.


dbdate: 03/15/2013
author: Li J
date: 12/20/2012
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23263863
trait: Hematology traits
initial_samplesize: 7,943 African American children, 6,234 European ancestry children
study:
GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.


dbdate: 03/06/2013
author: Makela KM
date: 12/17/2012
journal: Circ Cardiovasc Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23247145
trait: LDL (oxidized)
initial_samplesize: 2,080 European ancestry individuals
replication_samplesize: 4,238 European ancestry individuals
study:
Genome-wide association study pinpoints a new functional apolipoprotein B variant influencing oxidized low-density lipoprotein levels but not cardiovascular events: AtheroRemo Consortium.


dbdate: 03/11/2013
author: Jiang DK
date: 12/16/2012
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23242368
trait: Hepatocellular carcinoma (hepatitis B virus related)
initial_samplesize: 1,161 Chinese ancestry cases, 1,353 Chinese ancestry controls
replication_samplesize: 4,319 Chinese ancestry cases, 4,966 Chinese ancestry controls
study:
Genetic variants in STAT4 and HLA-DQ genes confer risk of hepatitis B virus-related hepatocellular carcinoma.


dbdate: 02/27/2013
author: Yu B
date: 12/16/2012
journal: Circ Cardiovasc Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23247143
trait: Cardiac Troponin-T levels
initial_samplesize: 9,491 European ancestry individuals, up to 2,053 African American individuals
study:
Association of genome-wide variation with highly sensitive cardiac troponin-T levels in European Americans and Blacks: a meta-analysis from atherosclerosis risk in communities and cardiovascular health studies.


dbdate: 02/19/2013
author: Clark SL
date: 12/12/2012
journal: Pharmacogenet Genomics
link: http://www.ncbi.nlm.nih.gov/pubmed/23241943
trait: Response to antipsychotic treatment
study:
Genome-wide association study of patient-rated and clinician-rated global impression of severity during antipsychotic treatment.

initial_samplesize:
Up to 421 European ancestry Schizophrenia cases, up to 214 African American individuals, up to 103 individuals


dbdate: 02/19/2013
author: Aragam N
date: 12/11/2012
journal: J Mol Neurosci
link: http://www.ncbi.nlm.nih.gov/pubmed/23229837
trait: Neuroticism
initial_samplesize: 2,748 European ancestry cases
study:
TMPRSS9 and GRIN2B are associated with neuroticism: a genome-wide association study in a European sample.


dbdate: 03/15/2013
author: Ramsey LB
date: 12/11/2012
journal: Blood
link: http://www.ncbi.nlm.nih.gov/pubmed/23233662
study: Genome-wide study of methotrexate clearance replicates SLCO1B1.
trait: Methotrexate clearance (acute lymphoblastic leukemia)
replication_samplesize: 699 European ancestry cases
initial_samplesize:
22 East Asian ancestry cases, 58 African ancestry, African American, or Afro-Caribbean ancestry cases, 266 Hispanic, or Latin American ancestry cases, 806 European ancestry cases, 127 other ancestry cases


dbdate: 12/16/2012
author: Hou S
date: 12/06/2012
journal: Arthritis Rheum
link: http://www.ncbi.nlm.nih.gov/pubmed/23001997
trait: Behcet's disease
initial_samplesize: 147 Han Chinese ancestry cases, 951 Han Chinese ancestry controls
replication_samplesize: 554 Han Chinese ancestry cases, 1,159 Han Chinese ancestry controls
study:
Identification of a susceptibility locus in STAT4 for Beh&#x000e7;et's disease in Han Chinese in a genome-wide association study.


dbdate: 02/08/2013
author: Le Clerc S
date: 12/06/2012
journal: J Invest Dermatol
link: http://www.ncbi.nlm.nih.gov/pubmed/23223146
trait: Aging (facial)
initial_samplesize: 502 European ancestry women
study:
A genome-wide association study in Caucasian women points out a putative role of the STXBP5L gene in facial photoaging.


dbdate: 03/05/2013
author: Zuo L
date: 12/06/2012
journal: Alcohol Clin Exp Res
link: http://www.ncbi.nlm.nih.gov/pubmed/23216389
trait: Alcohol and nictotine co-dependence
initial_samplesize: 818 European ancestry cases, 1,396 European ancestry controls
study:
Genome-wide significant association signals in IPO11-HTR1A region specific for alcohol and nicotine codependence.

replication_samplesize:
Up to 907 European ancestry cases, up to 2,830 European ancestry controls, up to 449 African American cases, up to 480 African American controls


dbdate: 02/20/2013
author: Adams LA
date: 12/05/2012
journal: Hepatology
link: http://www.ncbi.nlm.nih.gov/pubmed/23213074
trait: Non-alcoholic fatty liver disease histology (other)
initial_samplesize: 126 European ancestry adolescent cases, 802 European ancestry adolescent controls
study:
Association between liver-specific gene polymorphisms and their expression levels with nonalcoholic fatty liver disease.


dbdate: 04/09/2013
author: Comuzzie AG
date: 12/04/2012
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/23251661
trait: Obesity-related traits
initial_samplesize: 815 Hispanic children from 263 families
study:
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.


dbdate: 03/05/2013
author: Lasky-Su J
date: 12/04/2012
journal: Clin Exp Allergy
link: http://www.ncbi.nlm.nih.gov/pubmed/23181788
trait: Asthma
initial_samplesize: Up to 1,238 European ancestry cases, up to 2,617 European ancestry controls
study:
HLA-DQ strikes again: genome-wide association study further confirms HLA-DQ in the diagnosis of asthma among adults.

replication_samplesize:
Up to 1,837 European ancestry cases, up to 3,803 European ancestry controls, up to 2,806 cases, up to 2,150 controls, up to 603 Costa Rican ancestry cases and their parents


dbdate: 03/05/2013
author: Sprooten E
date: 12/04/2012
journal: Psychiatry Res
link: http://www.ncbi.nlm.nih.gov/pubmed/23218918
trait: White matter integrity
initial_samplesize: 70 unaffected relatives of patients with bipolar disorder, 80 controls
study:
White matter integrity as an intermediate phenotype: exploratory genome-wide association analysis in individuals at high risk of bipolar disorder.


dbdate: 03/19/2013
author: Tabassum R
date: 12/03/2012
journal: Diabetes
link: http://www.ncbi.nlm.nih.gov/pubmed/23209189
trait: Type 2 diabetes
initial_samplesize: 1,101 Indo-European ancestry cases, 1,027 Indo-European ancestry controls
study:
Genome-wide association study for type 2 diabetes in Indians identifies a new susceptibility locus at 2q21.

replication_samplesize:
3,607 Indo-European ancestry cases, 2,924 Indo-European ancestry controls, 1,184 Dravidian ancestry cases, 1,061 Dravidian ancestry controls, 11,285 European ancestry cases, 11,285 European ancestry controls


dbdate: 02/28/2013
author: Horikoshi M
date: 12/02/2012
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23202124
trait: Birth weight
initial_samplesize: Up to 26,836 European ancestry individuals
replication_samplesize: Up to 42,519 European ancestry individuals
study:
New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism.


dbdate: 02/20/2013
author: Fanous AH
date: 12/01/2012
journal: Am J Psychiatry
link: http://www.ncbi.nlm.nih.gov/pubmed/23212062
trait: Schizophrenia
initial_samplesize: 2,454 European ancestry cases
study:
Genome-wide association study of clinical dimensions of schizophrenia: polygenic effect on disorganized symptoms.


dbdate: 02/14/2013
author: Velez Edwards DR
date: 11/29/2012
journal: Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23192594
trait: Body mass index (interaction)
initial_samplesize: 8,203 African American women, 3,484 Hispanic ancestry women
study:
Gene-environment interactions and obesity traits among postmenopausal African-American and Hispanic women in the Women's Health Initiative SHARe Study.


dbdate: 02/06/2013
author: Deo R
date: 11/23/2012
journal: Heart Rhythm
link: http://www.ncbi.nlm.nih.gov/pubmed/23183192
trait: Resting heart rate
initial_samplesize: 13,372 African American individuals
study:
Common genetic variation near the connexin-43 gene is associated with resting heart rate in African Americans: a genome-wide association study of 13,372 participants.


dbdate: 01/30/2013
author: Justice CM
date: 11/18/2012
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23160099
trait: Sagittal craniosynostosis
initial_samplesize: 130 European ancestry trios
replication_samplesize: 172 Other ancestry cases, 548 Other ancestry controls
study:
A genome-wide association study identifies susceptibility loci for nonsyndromic sagittal craniosynostosis near BMP2 and within BBS9.


dbdate: 02/13/2014
author: Jonsson T
date: 11/14/2012
journal: N Engl J Med
link: http://www.ncbi.nlm.nih.gov/pubmed/23150908
study: Variant of TREM2 associated with the risk of Alzheimer's disease.
trait: Alzheimer's disease
initial_samplesize: 3,550 European ancestry cases, 8,888 European ancestry controls
replication_samplesize:
694 European ancestry cases, 4,375 European ancestry controls, 1,343 Other ancestry cases, 5,352 Other ancestry controls


dbdate: 02/01/2013
author: Lan Q
date: 11/11/2012
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23143601
trait: Lung cancer
initial_samplesize: 5,510 East Asian ancestry cases, 4,544 East Asian ancestry controls
replication_samplesize: 1,099 East Asian ancestry cases, 2,913 East Asian ancestry controls
study:
Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia.


dbdate: 01/23/2013
author: Whitcomb DC
date: 11/11/2012
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23143602
trait: Pancreatitis
initial_samplesize: 676 European ancestry cases, 4,507 European ancestry controls
replication_samplesize: 910 European ancestry cases, 4,170 European ancestry controls
study:
Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis.


dbdate: 01/29/2013
author: Aslibekyan S
date: 11/10/2012
journal: Nutr Metab Cardiovasc Dis
link: http://www.ncbi.nlm.nih.gov/pubmed/23149075
trait: Response to fenofibrate (adiponectin levels)
initial_samplesize: 793 European ancestry individuals
study:
Preliminary evidence of genetic determinants of adiponectin response to fenofibrate in the Genetics of Lipid Lowering Drugs and Diet Network.


dbdate: 02/06/2013
author: Levin AM
date: 11/10/2012
journal: J Allergy Clin Immunol
link: http://www.ncbi.nlm.nih.gov/pubmed/23146381
trait: IgE levels
initial_samplesize: 2,469 African American individuals, 259 Latino individuals, 1,564 European ancestry individuals
study:
A meta-analysis of genome-wide association studies for serum total IgE in diverse study populations.

replication_samplesize:
2,961 African American individuals, 1,477 Latino individuals, 649 European ancestry individuals, 680 Hutterites


dbdate: 01/18/2013
author: Butler AM
date: 11/08/2012
journal: Circ Cardiovasc Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23139255
trait: PR interval
initial_samplesize: 13,415 African American individuals
study:
Novel loci associated with PR interval in a genome-wide association study of 10 African American cohorts.


dbdate: 01/25/2013
author: Lee Y
date: 11/08/2012
journal: Carcinogenesis
link: http://www.ncbi.nlm.nih.gov/pubmed/23144319
trait: Non-small cell lung cancer
initial_samplesize: 348 Korean ancestry cases
study:
Prognostic implications of genetic variants in advanced non-small cell lung cancer: a genome-wide association study.


dbdate: 01/23/2013
author: Betcheva ET
date: 11/07/2012
journal: Psychiatr Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23142968
trait: Schizophrenia
initial_samplesize: 188 European ancestry cases, 376 European ancestry controls
replication_samplesize: 99 European ancestry cases, 328 European ancestry controls
study:
Whole-genome-wide association study in the Bulgarian population reveals HHAT as schizophrenia susceptibility gene.


dbdate: 01/22/2013
author: Brown CC
date: 11/01/2012
journal: Pharmacogenet Genomics
link: http://www.ncbi.nlm.nih.gov/pubmed/23047291
trait: Response to temozolomide
initial_samplesize: 516 European ancestry lymphoblastoid cell lines
study:
A genome-wide association analysis of temozolomide response using lymphoblastoid cell lines shows a clinically relevant association with MGMT.


dbdate: 01/30/2013
author: Chu AY
date: 11/01/2012
journal: Circ Cardiovasc Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23118302
trait: Lipoprotein-associated phospholipase A2 activity and mass
initial_samplesize: 6,851 European ancestry individuals
replication_samplesize: 13,664 European ancestry individuals
study:
Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.


dbdate: 01/11/2013
author: Candille SI
date: 10/31/2012
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/23118974
trait: Eye color
initial_samplesize: 175 European ancestry individuals
replication_samplesize: 293 European ancestry individuals
study:
Genome-wide association studies of quantitatively measured skin, hair, and eye pigmentation in four European populations.


dbdate: 01/11/2013
author: Yang M
date: 10/31/2012
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/23118916
trait: IgM levels
initial_samplesize: 1,999 Han Chinese ancestry individuals
replication_samplesize: 1,496 East Asian ancestry individuals
study:
Genome-wide scan identifies variant in TNFSF13 associated with serum IgM in a healthy Chinese male population.


dbdate: 01/16/2013
author: Guo YF
date: 10/30/2012
journal: Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23108985
trait: Body mass (lean)
initial_samplesize: 1,627 Han Chinese individuals
replication_samplesize: 2,286 European ancestry individuals
study:
Suggestion of GLYAT gene underlying variation of bone size and body lean mass as revealed by a bivariate genome-wide association study.


dbdate: 01/15/2013
author: Wang LE
date: 10/29/2012
journal: Cancer Res
link: http://www.ncbi.nlm.nih.gov/pubmed/23108145
trait: Lung Cancer (DNA repair capacity)
initial_samplesize: 914 European ancestry non-small cell lung cancer cases, 860 European ancestry controls
replication_samplesize: 679 European ancestry ancestry non-small cell lung cancer cases, 695 European ancestry controls
study:
Genome-wide association study reveals novel genetic determinants of DNA repair capacity in lung cancer.


dbdate: 01/11/2013
author: Nyholt DR
date: 10/28/2012
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23104006
study: Genome-wide association meta-analysis identifies new endometriosis risk loci.
trait: Endometriosis
replication_samplesize: 1,044 Japanese ancestry, 4,017 Japanese ancestry controls
initial_samplesize:
3,181 European ancestry cases, 8,075 European ancestry controls, 1,423 Japanese ancestry cases, 1,318 Japanese ancestry controls


dbdate: 01/18/2013
author: Jin G
date: 10/25/2012
journal: Am J Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23103227
study: Genetic variants at 6p21.1 and 7p15.3 are associated with risk of multiple cancers in Han Chinese.
trait: Multiple cancers (lung cancer, gastric cancer, and squamous cell carcinoma)
initial_samplesize:
2,331 Han Chinese ancestry lung cancer cases, 1,006 Han Chinese ancestry non-cardia gastric cancer cases, 2,031 Han Chinese ancestry esophageal squamous-cell carcinoma cases, 4,006 Han Chinese ancestry controls

replication_samplesize:
2,665 Han Chinese ancestry lung cancer cases, 3,330 Han Chinese ancestry non-cardia gastric cancer cases, 3,006 Han Chinese ancestry esophageal squamous-cell carcinoma cases, 11,436 Han Chinese ancestry controls


dbdate: 01/10/2013
author: Amin Al Olama A
date: 10/12/2012
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23065704
trait: Prostate cancer
study:
A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease.

initial_samplesize:
5,132 European ancestry non-aggressive cases, 5,953 European ancestry aggressive cases, 11,463 European ancestry controls

replication_samplesize:
22,387 European ancestry non-aggressive cases, 2,008 European ancestry aggressive cases, up to 24,726 European ancestry controls


dbdate: 01/16/2013
author: Meng W
date: 10/09/2012
journal: Invest Ophthalmol Vis Sci
link: http://www.ncbi.nlm.nih.gov/pubmed/23049088
trait: Myopia (pathological)
initial_samplesize: 187 European ancestry cases, 1064 European ancestry controls
study:
A genome-wide association study provides evidence for association of chromosome 8p23 (MYP10) and 10q21.1 (MYP15) with high myopia in the French Population.


dbdate: 12/21/2012
author: Hirota T
date: 10/07/2012
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23042114
trait: Atopic dermatitis
initial_samplesize: 1,472 Japanese ancestry cases, 7,971 Japanese ancestry controls
replication_samplesize: 1,856 Japanese ancestry cases, 7,021 Japanese ancestry controls
study:
Genome-wide association study identifies eight new susceptibility loci for atopic dermatitis in the Japanese population.


dbdate: 01/09/2013
author: Lee YH
date: 10/07/2012
journal: Mol Biol Rep
link: http://www.ncbi.nlm.nih.gov/pubmed/23053960
trait: Systemic lupus erythematosus
initial_samplesize: 1,527 European ancestry cases, 3,421 European ancestry controls,
study:
Genome-wide pathway analysis of genome-wide association studies on systemic lupus erythematosus and rheumatoid arthritis.


dbdate: 01/09/2013
author: Traylor M
date: 10/05/2012
journal: Lancet Neurol
link: http://www.ncbi.nlm.nih.gov/pubmed/23041239
trait: Stroke (ischemic)
initial_samplesize: 12,389 European ancestry cases, 62,004 European ancestry controls
study:
Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies.

replication_samplesize:
1,322 Pakistani ancestry cases, 1,143 Pakistani ancestry controls, 12,025 European ancestry cases, 27,940 European ancestry controls


dbdate: 12/21/2012
author: Surakka I
date: 10/03/2012
journal: Twin Res Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23031429
trait: Apolipoprotein Levels
initial_samplesize: 1,720 European ancestry monozygotic twins
study:
A genome-wide association study of monozygotic twin-pairs suggests a locus related to variability of serum high-density lipoprotein cholesterol.


dbdate: 12/11/2012
author: Xu J
date: 09/30/2012
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23023329
trait: Prostate cancer
initial_samplesize: 1,417 Han Chinese ancestry cases, 1,008 Han Chinese ancestry controls
replication_samplesize: 3,067 Han Chinese ancestry cases, 7,926 Han Chinese ancestry controls
study:
Genome-wide association study in Chinese men identifies two new prostate cancer risk loci at 9q31.2 and 19q13.4.


dbdate: 12/07/2012
author: Ramasamy A
date: 09/28/2012
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/23028483
trait: Asthma
initial_samplesize: 1,716 European ancestry cases, 16,888 European ancestry controls
replication_samplesize: 4,035 European ancestry cases, 11,251 European ancestry controls
study:
Genome-wide association studies of asthma in population-based cohorts confirm known and suggested loci and identify an additional association near HLA.


dbdate: 12/21/2012
author: Kumasaka N
date: 09/25/2012
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/23049750
trait: Smoking behavior
initial_samplesize: 11,696 Japanese ancestry smokers
replication_samplesize: 5,462 Japanese ancestry smokers
study:
Haplotypes with copy number and single nucleotide polymorphisms in CYP2A6 locus are associated with smoking quantity in a Japanese population.


dbdate: 12/05/2012
author: Mangino M
date: 09/25/2012
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23001564
trait: Telomere length
initial_samplesize: 9,190 European ancestry individuals
replication_samplesize: 2,226 individuals
study:
Genome-wide meta-analysis points to CTC1 and ZNF676 as genes regulating telomere homeostasis in humans.


dbdate: 12/06/2012
author: Niu N M D Ph D
date: 09/24/2012
journal: BMC Cancer
link: http://www.ncbi.nlm.nih.gov/pubmed/23006423
trait: Response to taxane treatment (docetaxel)
study:
Genetic association with overall survival of taxane-treated lung cancer patients - A genome-wide association study in human lymphoblastoid cell lines followed by a clinical association study.

initial_samplesize:
96 African American lymphoblastoid cell lines, 96 European ancestry lymphoblastoid cell lines, 96 Han Chinese ancestry lymphoblastoid cell lines


dbdate: 12/04/2012
author: Voruganti VS
date: 09/24/2012
journal: Cytokine
link: http://www.ncbi.nlm.nih.gov/pubmed/23017229
trait: Monocyte chemoattractant protein-1
initial_samplesize: 815 Hispanic children
study:
Genome-wide association replicates the association of Duffy antigen receptor for chemokines (DARC) polymorphisms with serum monocyte chemoattractant protein-1 (MCP-1) levels in Hispanic children.


dbdate: 12/06/2012
author: Yang JJ
date: 09/24/2012
journal: Blood
link: http://www.ncbi.nlm.nih.gov/pubmed/23007406
trait: Acute lymphoblastic leukemia (childhood)
study:
Genome-wide association study identifies germline polymorphisms associated with relapse of childhood acute lymphoblastic leukemia.

initial_samplesize:
1,268 cases of European, South Asian, East Asian, African American/Afro-Caribbean, Hispanic and other ancestries

replication_samplesize:
1,267 cases of European, South Asian, East Asian, African American/Afro-Caribbean, Hispanic and other ancestries


dbdate: 12/02/2012
author: Orr N
date: 09/23/2012
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23001122
trait: Breast cancer (male)
initial_samplesize: 823 European ancestry cases, 2,795 European ancestry controls
replication_samplesize: 438 European ancestry cases, 474 European ancestry controls
study:
Genome-wide association study identifies a common variant in RAD51B associated with male breast cancer risk.


dbdate: 12/04/2012
author: Arning A
date: 09/20/2012
journal: Blood
link: http://www.ncbi.nlm.nih.gov/pubmed/22990015
trait: Stroke (pediatric)
initial_samplesize: 270 European ancestry trios
study:
A genome-wide association study identifies a gene network of ADAMTS genes in the predisposition to pediatric stroke.


dbdate: 12/11/2012
author: Sandholm N
date: 09/20/2012
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23028342
study: New susceptibility loci associated with kidney disease in type 1 diabetes.
trait: Type 1 diabetes nephropathy
initial_samplesize:
Up to 2,916 European ancestry Type 1 Diabetes cases with nephropathy, 3,315 European ancestry Type 1 Diabetes cases without nephropathy

replication_samplesize:
Up to 1,493 European ancestry Type 1 Diabetes cases with nephropathy, 3,191 European ancestry Type 1 Diabetes cases without nephropathy


dbdate: 12/06/2012
author: Williams FM
date: 09/19/2012
journal: Ann Rheum Dis
link: http://www.ncbi.nlm.nih.gov/pubmed/22993228
trait: Disc degeneration (lumbar)
initial_samplesize: 4,683 European ancestry individuals
study:
Novel genetic variants associated with lumbar disc degeneration in northern Europeans: a meta-analysis of 4600 subjects.


dbdate: 11/28/2012
author: Huang J
date: 09/18/2012
journal: Blood
link: http://www.ncbi.nlm.nih.gov/pubmed/22990020
trait: Plasminogen activator inhibitor type 1 levels (PAI-1)
initial_samplesize: 19,599 European ancestry individuals
replication_samplesize: 10,764 European ancestry individuals
study:
Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation.


dbdate: 11/29/2012
author: Nakamura M
date: 09/18/2012
journal: Am J Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23000144
trait: Primary biliary cirrhosis
initial_samplesize: 487 Japanese ancestry cases, 476 Japanese ancestry controls
replication_samplesize: 787 Japanese ancestry cases, 615 Japanese ancestry controls
study:
Genome-wide association study identifies TNFSF15 and POU2AF1 as susceptibility loci for primary biliary cirrhosis in the Japanese population.


dbdate: 11/28/2012
author: Myouzen K
date: 09/13/2012
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/23028356
trait: Rheumatoid arthritis
initial_samplesize: 2,303 Japanese ancestry cases, 3,380 Japanese ancestry controls
replication_samplesize: 5,604 Japanese ancestry cases, 31,982 Japanese ancestry controls
study:
Functional variants in NFKBIE and RTKN2 involved in activation of the NF-&#x003ba;B pathway are associated with rheumatoid arthritis in Japanese.


dbdate: 11/30/2012
author: Siddiq A
date: 09/13/2012
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22976474
trait: Breast cancer
study:
A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11.

initial_samplesize:
3,666 European ancestry cases, 28,864 European ancestry controls, 1,004 African American cases, 2,744 African American controls

replication_samplesize:
562 European ancestry cases, 6,410 European ancestry controls, 84 Japanese ancestry cases, 830 Japanese ancestry controls, 300 Latino cases, 1,164 Latino controls


dbdate: 04/09/2013
author: Tang WH
date: 09/13/2012
journal: Arterioscler Thromb Vasc Biol
link: http://www.ncbi.nlm.nih.gov/pubmed/22982463
trait: Paraoxonase activity
initial_samplesize: 2,136 European ancestry individuals
study:
Clinical and genetic association of serum paraoxonase and arylesterase activities with cardiovascular risk.


dbdate: 12/11/2012
author: Wu C
date: 09/09/2012
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22960999
trait: Esophageal cancer (alcohol interaction)
initial_samplesize: 2,031 Han Chinese ancestry cases, 2,044 Han Chinese ancestry controls
replication_samplesize: 8,092 Chinese ancestry cases, 8,620 Chinese ancestry controls
study:
Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions.


dbdate: 01/15/2013
author: Buck D
date: 09/08/2012
journal: Ann Neurol
link: http://www.ncbi.nlm.nih.gov/pubmed/23225573
trait: IgG levels
initial_samplesize: 229 European ancestry multiple sclerosis cases
replication_samplesize: 409 European ancestry multiple sclerosis cases
study:
Genetic variants in the immunoglobulin heavy chain locus are associated with the IgG index in multiple sclerosis.


dbdate: 11/06/2012
author: Elgazzar S
date: 09/06/2012
journal: J Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22951594
trait: Breast cancer
initial_samplesize: 1,086 Japanese ancestry cases, 1,816 Japanese ancestry controls
replication_samplesize: 1,653 Japanese ancestry cases, 2,797 Japanese ancestry controls
study:
A genome-wide association study identifies a genetic variant in the SIAH2 locus associated with hormonal receptor-positive breast cancer in Japanese.


dbdate: 11/13/2012
author: Foroud T
date: 09/06/2012
journal: Stroke
link: http://www.ncbi.nlm.nih.gov/pubmed/22961961
trait: Intracranial aneurysm
initial_samplesize: 1,483 European ancestry cases, 1,683 European ancestry controls
study:
Genome-wide association study of intracranial aneurysms confirms role of Anril and SOX17 in disease risk.


dbdate: 11/15/2012
author: Li H
date: 09/06/2012
journal: Diabetes
link: http://www.ncbi.nlm.nih.gov/pubmed/22961080
trait: Type 2 diabetes
initial_samplesize: 1,839 Han Chinese ancestry cases, 1,873 Han Chinese ancestry controls
study:
A genome-wide association study identifies GRK5 and RASGRP1 as type 2 diabetes loci in Chinese Hans.

replication_samplesize:
15,979 East Asian ancestry cases, 19,360 East Asian ancestry controls, 794 Singaporean Malay ancestry cases, 1,240 Singaporean Malay ancestry controls, 159 South Asian ancestry cases, 1,624 South Asian ancestry controls


dbdate: 11/13/2012
author: Peters MJ
date: 09/06/2012
journal: Ann Rheum Dis
link: http://www.ncbi.nlm.nih.gov/pubmed/22956598
trait: Pain
initial_samplesize: 1,308 European ancestry female cases, 5,791 European ancestry female controls
replication_samplesize: 1,480 European ancestry female cases, 7,989 European ancestry female controls
study:
Genome-wide association study meta-analysis of chronic widespread pain: evidence for involvement of the 5p15.2 region.


dbdate: 11/02/2012
author: EPICURE Consortium
date: 09/04/2012
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22949513
trait: Epilepsy (generalized)
study:
Genome-wide association analysis of genetic generalized epilepsies implicates susceptibility loci at 1q43, 2p16.1, 2q22.3 and 17q21.32

initial_samplesize:
702 European ancestry GAE cases, 586 European ancestry JME cases, 239 European ancestry other GGE cases, 2,461 European ancestry controls

replication_samplesize:
347 European ancestry GAE parent-child trios, 166 European ancestry JME parent-child trios, 91 European ancestry other GGE parent-child trios, 385 European ancestry GAE cases, 382 European ancestry JME cases, 122 European ancestry other GGE cases, up to 889 European ancestry controls


dbdate: 11/02/2012
author: Diskin SJ
date: 09/02/2012
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22941191
study: Common variation at 6q16 within HACE1 and LIN28B influences susceptibility to neuroblastoma.
trait: Neuroblastoma
initial_samplesize: 2,101 European ancestry cases, 4,202 European ancestry controls
replication_samplesize:
351 European ancestry cases, 780 European ancestry controls, 365 African American cases, 2,491 African American controls


dbdate: 11/02/2012
author: Holliday EG
date: 09/02/2012
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22941190
study: Common variants at 6p21.1 are associated with large artery atherosclerotic stroke.
trait: Stroke (ischemic)
initial_samplesize:
421 European ancestry large artery atherosclerosis cases, 741 European ancestry ischemic stroke cases, 1,244 European ancestry controls

replication_samplesize:
1,715 European ancestry large artery atherosclerosis cases, 9,552 European ancestry ischemic stroke cases, 52,695 European ancestry controls


dbdate: 11/19/2012
author: Cummings AC
date: 09/01/2012
journal: Ann Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22881374
trait: Alzheimer's disease (late onset)
initial_samplesize: 109 Amish cases, 689 Amish controls
study:
Genome-wide association and linkage study in the Amish detects a novel candidate late-onset Alzheimer disease gene.


dbdate: 11/28/2012
author: Levinson DF
date: 09/01/2012
journal: Am J Psychiatry
link: http://www.ncbi.nlm.nih.gov/pubmed/22885689
study: Genome-wide association study of multiplex schizophrenia pedigrees.
trait: Schizophrenia
initial_samplesize:
1,218 European ancestry cases, 990 European ancestry controls, 139 Other ancestry cases, 114 Other ancestry controls


dbdate: 11/05/2012
author: Han Y
date: 08/31/2012
journal: Bone
link: http://www.ncbi.nlm.nih.gov/pubmed/22960237
trait: Comprehensive strength and appendicular lean mass
initial_samplesize: 825 Chinese ancestry females, 802 Chinese ancestry males
replication_samplesize: 1,059 European ancestry males, 2,227 European ancestry females
study:
Bivariate genome-wide association study suggests fatty acid desaturase genes and cadherin DCHS2 for variation of both compressive strength index and appendicular lean mass in males.


dbdate: 10/28/2012
author: Jin G
date: 08/30/2012
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22936694
trait: Androgen levels
initial_samplesize: 3,225 European ancestry males
study:
Genome-wide association study identifies a new locus JMJD1C at 10q21 that may influence serum androgen levels in men.


dbdate: 11/16/2012
author: Julia A
date: 08/30/2012
journal: Gut
link: http://www.ncbi.nlm.nih.gov/pubmed/22936669
trait: Crohn's disease
initial_samplesize: 1,277 European ancestry cases, 1,488 European ancestry controls
replication_samplesize: 1,365 European ancestry cases, 1,396 European ancestry controls
study:
A genome-wide association study on a southern European population identifies a new Crohn's disease susceptibility locus at RBX1-EP300.


dbdate: 11/05/2012
author: Hart AB
date: 08/28/2012
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/22952603
trait: Response to amphetamines
study:
Genome-wide association study of d-amphetamine response in healthy volunteers identifies putative associations, including cadherin 13 (CDH13).

initial_samplesize:
1 American Indian ancestry individual, 18 African American individuals, 10 Asian ancestry individuals, 325 European ancestry individuals, 17 Hispanic individuals, 6 other ancestry individuals, 4 individuals


dbdate: 11/02/2012
author: Reiner AP
date: 08/28/2012
journal: Am J Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22939635
trait: C-reactive protein
initial_samplesize: 8,280 African American females, 3,548 Hispanic females
replication_samplesize: 3,787 African American females, 3,548 Hispanic females, 5,656 European ancestry individuals
study:
Genome-wide association and population genetic analysis of C-reactive protein in African American and Hispanic American women.


dbdate: 10/24/2012
author: Vithana EN
date: 08/26/2012
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22922875
trait: Glaucoma (primary open-angle)
study:
Genome-wide association analyses identify three new susceptibility loci for primary angle closure glaucoma.

initial_samplesize:
1,281 East Asian ancestry cases, 1,987 East Asian ancestry controls, 3,065 Singaporean Malay ancestry controls, 573 Singaporean Asian Indian ancestry cases, 2,538 Singaporean Asian Indian ancestry controls, 2,018 Vietnamese ancestry controls

replication_samplesize:
1,545 East Asian ancestry cases, 3,756 East Asian ancestry controls, 165 Saudi Arabian ancestry cases, 175 Saudi Arabian ancestry controls, 127 European ancestry cases, 4,703 European ancestry controls, 80 Indian ancestry cases, 309 Indian ancestry controls


dbdate: 11/19/2012
author: Lee HJ
date: 08/25/2012
journal: J Affect Disord
link: http://www.ncbi.nlm.nih.gov/pubmed/22925353
trait: Bipolar disorder
initial_samplesize: 2,191 European ancestry cases, 1,434 European ancestry controls
study:
A genome-wide association study of seasonal pattern mania identifies NF1A as a possible susceptibility gene for bipolar disorder.


dbdate: 10/23/2012
author: Cheng I
date: 08/24/2012
journal: Cancer Epidemiol Biomarkers Prev
link: http://www.ncbi.nlm.nih.gov/pubmed/22923026
study: Evaluating genetic risk for prostate cancer among Japanese and Latinos.
trait: Prostate cancer
initial_samplesize:
1,033 Japanese ancestry cases, 1,042 Japanese ancestry controls, 1,043 Latino cases, 1,057 Latino controls

replication_samplesize:
1,583 Japanese ancestry cases, 3,386 Japanese ancestry  controls, 1,854 European ancestry cases, 3,748 European ancestry controls


dbdate: 11/19/2012
author: Rasmussen-Torvik LJ
date: 08/23/2012
journal: Clin Transl Sci
link: http://www.ncbi.nlm.nih.gov/pubmed/23067351
trait: LDL cholesterol
initial_samplesize: 1,249 African American individuals
study:
High density GWAS for LDL cholesterol in African Americans using electronic medical records reveals a strong protective variant in APOE.


dbdate: 10/23/2012
author: Boraska V
date: 08/22/2012
journal: Am J Med Genet B Neuropsychiatr Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22911880
trait: Eating disorders
initial_samplesize: Up to 2,567 European ancestry individuals
replication_samplesize: Up to 767 European ancestry cases, up to 486 European ancestry controls
study:
Genome-wide association analysis of eating disorder-related symptoms, behaviors, and personality traits.


dbdate: 10/12/2012
author: Hibar DP
date: 08/18/2012
journal: Brain Imaging Behav
link: http://www.ncbi.nlm.nih.gov/pubmed/22903471
trait: Lentiform nucleus volume
study:
Genome-wide association identifies genetic variants associated with lentiform nucleus volume in N&#x02009;=&#x02009;1345 young and elderly subjects.

initial_samplesize:
162 European ancestry Alzheimer's disease cases, 346 European ancestry mild cognitive impairment cases, 198 European ancestry controls, 639 European ancestry individuals from 364 families


dbdate: 11/21/2012
author: Inouye M
date: 08/16/2012
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22916037
trait: Metabolite levels
initial_samplesize: 6,608 European ancestry individuals
study:
Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.


dbdate: 11/22/2012
author: Timofeeva MN
date: 08/16/2012
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22899653
trait: Lung cancer
initial_samplesize: up to 14,900 European ancestry cases, up to 29,485 European ancestry controls
replication_samplesize: 2,338 Han Chinese ancestry cases, 3,077 Han Chinese ancestry controls
study:
Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls.


dbdate: 10/23/2012
author: Scharf JM
date: 08/14/2012
journal: Mol Psychiatry
link: http://www.ncbi.nlm.nih.gov/pubmed/22889924
study: Genome-wide association study of Tourette's syndrome.
trait: Tourette syndrome
replication_samplesize: 211 Latin American ancestry cases, 285 Latin American ancestry controls
initial_samplesize:
778 European ancestry cases, 4,414 European ancestry controls, 242 Ashkenazi Jewish cases, 354 Ashkenazi Jewish controls, 265 French Canadian founder cases, 196 French Canadian founder controls


dbdate: 10/12/2012
author: Stewart SE
date: 08/14/2012
journal: Mol Psychiatry
link: http://www.ncbi.nlm.nih.gov/pubmed/22889921
study: Genome-wide association study of obsessive-compulsive disorder.
trait: Obsessive-compulsive disorder
initial_samplesize:
1,279 European ancestry cases, 5,139 European ancestry controls, 93 South African Afrikaner ancestry cases, 158  South African Afrikaner ancestry controls, 93 Ashkenazi Jewish cases, 260 Ashkenazi Jewish controls, 299 European ancestry trios, 101 trios


dbdate: 10/09/2012
author: Frazier-Wood AC
date: 08/09/2012
journal: Pharmacogenet Genomics
link: http://www.ncbi.nlm.nih.gov/pubmed/22890011
trait: Response to fenofibrate
initial_samplesize: 817 European ancestry individuals
study:
Genome-wide association study indicates variants associated with insulin signaling and inflammation mediate lipoprotein responses to fenofibrate.


dbdate: 10/23/2012
author: Hu L
date: 08/07/2012
journal: Clin Cancer Res
link: http://www.ncbi.nlm.nih.gov/pubmed/22872573
trait: Response to platinum-based chemotherapy in non-small-cell lung cancer
initial_samplesize: 528 Han Chinese ancestry cases
replication_samplesize: 340 Han Chinese ancestry cases, 409 European ancestry cases
study:
Genome-wide association study of prognosis in advanced non-small cell lung cancer patients receiving platinum-based chemotherapy.


dbdate: 09/29/2012
author: Irish Schizophrenia Genomics Consortium & the Wellcome Trust Case Control Consortium 2
date: 08/07/2012
journal: Biol Psychiatry
link: http://www.ncbi.nlm.nih.gov/pubmed/22883433
trait: Schizophrenia
initial_samplesize: 1,606 European ancestry cases, 1,794 European ancestry controls
replication_samplesize: 13,195 European ancestry cases, 31,021 European ancestry controls
study:
Genome-wide association study implicates HLA-C*01:02 as a risk factor at the major histocompatibility complex locus in schizophrenia.


dbdate: 10/13/2012
author: Cheung CL
date: 08/05/2012
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22863731
trait: Thyrotoxic hypokalemic periodic paralysis
initial_samplesize: 69 Chinese ancestry cases, 1,170 East Asian ancestry controls,
replication_samplesize: 54 Chinese ancestry cases, 400 Taiwanese ancestry controls
study:
Genome-wide association study identifies a susceptibility locus for thyrotoxic periodic paralysis at 17q24.3.


dbdate: 10/09/2012
author: Ludwig KU
date: 08/05/2012
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22863734
trait: Orofacial clefts
initial_samplesize: Up to 666 European ancestry trios, 399 European ancestry cases, 1,318 European ancestry controls
replication_samplesize: up to 795 East Asian ancestry trios
study:
Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci.


dbdate: 10/13/2012
author: Yang C
date: 08/03/2012
journal: Immunogenetics
link: http://www.ncbi.nlm.nih.gov/pubmed/22864923
trait: IgA levels
initial_samplesize: 1,999 Han Chinese ancestry males
replication_samplesize: 1,496 East Asian ancestry males
study:
Genome-wide association study identifies TNFSF13 as a susceptibility gene for IgA in a South Chinese population in smokers.


dbdate: 09/26/2012
author: Patin E
date: 07/26/2012
journal: Gastroenterology
link: http://www.ncbi.nlm.nih.gov/pubmed/22841784
trait: Hepatitis C induced liver fibrosis
initial_samplesize: 1,161 European ancestry HCV-infected individuals
replication_samplesize: 1,181 European ancestry HCV-infected individuals
study:
Genome-wide association study identifies variants associated with progression of liver fibrosis from HCV infection.


dbdate: 09/21/2012
author: Qi Q
date: 07/26/2012
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22843503
trait: Resistin levels
initial_samplesize: 3,248 European ancestry individuals
replication_samplesize: 659 European ancestry individuals
study:
Genome-wide association analysis identifies TYW3/CRYZ and NDST4 loci associated with circulating resistin levels.


dbdate: 09/26/2012
author: Wilk JB
date: 07/26/2012
journal: Am J Respir Crit Care Med
link: http://www.ncbi.nlm.nih.gov/pubmed/22837378
trait: Airflow obstruction
initial_samplesize: up to 3,368 European ancestry cases, up to 29,507 European ancestry controls
replication_samplesize: 331 European ancestry cases, 2,550 European ancestry controls
study:
Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.


dbdate: 09/20/2012
author: Verweij KJ
date: 07/24/2012
journal: Addict Biol
link: http://www.ncbi.nlm.nih.gov/pubmed/22823124
trait: Cannabis use (initiation)
initial_samplesize: 10,091 individuals from 4,622 families
study:
The genetic aetiology of cannabis use initiation: a meta-analysis of genome-wide association studies and a SNP-based heritability estimation.


dbdate: 09/26/2012
author: Ellinghaus D
date: 07/23/2012
journal: Hepatology
link: http://www.ncbi.nlm.nih.gov/pubmed/22821403
trait: Sclerosing cholangitis and ulcerative colitis (combined)
study:
Genome-wide association analysis in primary sclerosing cholangitis and ulcerative colitis identifies risk loci at GPR35 and TCF4.

initial_samplesize:
Up to 389 European ancestry primary sclerosing cholangitis cases, 987 European ancestry ulcerative colitis cases, 2,968 European ancestry controls

replication_samplesize:
1,012 European ancestry primary sclerosing cholangitis cases, 4,444 European ancestry ulcerative colitis cases, 11,659 European ancestry controls


dbdate: 09/18/2012
author: Hoehn R
date: 07/20/2012
journal: Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22814818
trait: Central corneal thickness
initial_samplesize: 3,931 European ancestry individuals
replication_samplesize: 1,418 European ancestry individuals
study:
Population-based meta-analysis in Caucasians confirms association with COL5A1 and ZNF469 but not COL8A2 with central corneal thickness.


dbdate: 09/25/2012
author: Coviello AD
date: 07/19/2012
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22829776
trait: Sex hormone-binding globulin levels
initial_samplesize: 21,791 European ancestry individuals
replication_samplesize: 8,175 European ancestry individuals
study:
A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation.


dbdate: 11/22/2012
author: Gregersen PK
date: 07/16/2012
journal: Ann Neurol
link: http://www.ncbi.nlm.nih.gov/pubmed/23055271
trait: Myasthenia gravis
initial_samplesize: 400 European ancestry cases, 5,505 European ancestry controls
replication_samplesize: 249 European ancestry cases, 3,415 European ancestry controls
study:
Risk for myasthenia gravis maps to a (151) Pro&#x02192;Ala change in TNIP1 and to human leukocyte antigen-B*08.


dbdate: 09/18/2012
author: Okada Y
date: 07/15/2012
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22797727
trait: Renal function-related traits (BUN)
initial_samplesize: 39,717 East Asian ancestry individuals
replication_samplesize: 17,461 East Asian ancestry individuals
study:
Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.


dbdate: 09/20/2012
author: Shiraishi K
date: 07/15/2012
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22797724
trait: Lung adenocarcinoma
initial_samplesize: 1,695 Japanese ancestry cases, 5,333 Japanese ancestry controls
replication_samplesize: 4,334 Japanese ancestry cases, 8,202 Japanese ancestry controls
study:
A genome-wide association study identifies two new susceptibility loci for lung adenocarcinoma in the Japanese population.


dbdate: 09/12/2012
author: Chen G
date: 07/12/2012
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22791750
trait: Insulin-related traits
initial_samplesize: 927 African American non-diabetic individuals
replication_samplesize: 570 West African ancestry non-diabetic individuals
study:
Genome-wide association study identifies novel loci association with fasting insulin and insulin resistance in African Americans.


dbdate: 09/20/2012
author: Li S
date: 07/12/2012
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22807686
trait: Hepatocellular carcinoma
initial_samplesize: 1,538 Han Chinese ancestry HBV-positive HCC cases, 1,465 Han Chinese ancestry chronic HBV carriers
replication_samplesize: 4,431 Han Chinese ancestry HBV-positive HCC cases, 4,725 Han Chinese ancestry chronic HBV carriers
study:
GWAS identifies novel susceptibility loci on 6p21.32 and 21q21.3 for hepatocellular carcinoma in chronic hepatitis B virus carriers.


dbdate: 07/19/2012
author: Liao M
date: 07/07/2012
journal: Genes Immun
link: http://www.ncbi.nlm.nih.gov/pubmed/22673310
trait: IgG levels
initial_samplesize: 1,999 Chinese ancestry males
replication_samplesize: 1,496 Chinese ancestry males
study:
Genome-wide association study identifies common variants at TNFRSF13B associated with IgG level in a healthy Chinese male population.


dbdate: 09/12/2012
author: Himes BE
date: 07/05/2012
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22792082
trait: Asthma (bronchodilator response)
initial_samplesize: 1,644 European ancestry asthmatic cases
replication_samplesize: 1,051 European ancestry asthmatic cases
study:
Genome-wide association analysis in asthma subjects identifies SPATS2L as a novel bronchodilator response gene.


dbdate: 09/11/2012
author: Medina-Gomez C
date: 07/05/2012
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22792070
trait: Bone mineral density
initial_samplesize: 1,834 European ancestry children, 825 children
replication_samplesize: 11,052 European ancestry individuals
study:
Meta-analysis of genome-wide scans for total body BMD in children and adults reveals allelic heterogeneity and age-specific effects at the WNT16 locus.


dbdate: 09/12/2012
author: Zheng HF
date: 07/05/2012
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22792071
trait: Bone mineral density
initial_samplesize: 5672 European ancestry individuals
study:
WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk.


dbdate: 09/21/2012
author: Adkins DE
date: 07/03/2012
journal: Transl Psychiatry
link: http://www.ncbi.nlm.nih.gov/pubmed/22760553
study: Genome-wide pharmacogenomic study of citalopram-induced side effects in STAR*D.
trait: Response to citalopram treatment
initial_samplesize:
1,392 European ancestry depression cases, 264 African American depression cases, 106 depression cases


dbdate: 09/12/2012
author: Loughlin
date: 07/02/2012
journal: Lancet
link: http://www.ncbi.nlm.nih.gov/pubmed/22763110
trait: Osteoarthritis
initial_samplesize: 7,410 European ancestry cases, 11,009 European ancestry controls
replication_samplesize: 7,473 European ancestry cases, 42,938 European ancestry controls
study:
Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study.


dbdate: 09/08/2012
author: Byrne EM
date: 07/01/2012
journal: Sleep
link: http://www.ncbi.nlm.nih.gov/pubmed/22754043
trait: Insomnia (caffeine-induced)
initial_samplesize: 2,402 European ancestry individuals from 1,470 families
study:
A genome-wide association study of caffeine-related sleep disturbance: confirmation of a role for a common variant in the adenosine receptor.


dbdate: 09/20/2012
author: Lu X
date: 07/01/2012
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22751097
trait: Coronary heart disease
initial_samplesize: 1,515 Han Chinese ancestry cases, 5,019 Han Chinese ancestry controls
replication_samplesize: 15,460 Han Chinese ancestry cases, 11,472 Han Chinese ancestry controls
study:
Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease.


dbdate: 08/10/2012
author: Hai R
date: 06/29/2012
journal: Sci China Life Sci
link: http://www.ncbi.nlm.nih.gov/pubmed/22744181
trait: Lean body mass and age at menarche (combined)
initial_samplesize: 801 Han Chinese ancestry females
replication_samplesize: 1,692 European ancestry females
study:
Bivariate genome-wide association study suggests that the DARC gene influences lean body mass and age at menarche.


dbdate: 08/10/2012
author: Nishida N
date: 06/21/2012
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/22737229
trait: Hepatitis B (viral clearance)
study:
Genome-wide association study confirming association of HLA-DP with protection against chronic hepatitis B and viral clearance in Japanese and Korean.

initial_samplesize:
181 East Asian ancestry HBV carriers, 184 East Asian ancestry controls, 185 East Asian ancestry spontaneously HBV-resolved individuals

replication_samplesize:
Up to 8,045 East Asian ancestry HBV carriers, up to 9,003 East Asian ancestry controls, and up to 3,995 East Asian ancestry spontaneously HBV-resolved individuals


dbdate: 08/08/2012
author: Hager J
date: 06/20/2012
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/22745674
trait: Coronary heart disease
initial_samplesize: 1,949 Middle Eastern ancestry individuals
replication_samplesize: 2,547 Middle Eastern ancestry individuals
study:
Genome-wide association study in a Lebanese cohort confirms PHACTR1 as a major determinant of coronary artery stenosis.


dbdate: 08/30/2012
author: Sobrin L
date: 06/15/2012
journal: Ophthalmology
link: http://www.ncbi.nlm.nih.gov/pubmed/22705344
trait: Age-related macular degeneration (CNV vs. GA)
study:
Heritability and genome-wide association study to assess genetic differences between advanced age-related macular degeneration subtypes.

initial_samplesize:
1,775 European ancestry choroidal neovascularization cases, 819 European ancestry geographic atrophy cases,

replication_samplesize:
4,515 European and unknown ancestry choroidal neovascularization cases, 868 European and unknown ancestry geographic atrophy cases


dbdate: 08/10/2012
author: Kawaguchi T
date: 06/14/2012
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/22719876
trait: Nonalcoholic fatty liver disease
initial_samplesize: 529 Japanese ancestry cases, 932 Japanese ancestry controls
study:
Genetic polymorphisms of the human PNPLA3 gene are strongly associated with severity of non-alcoholic fatty liver disease in Japanese.


dbdate: 08/15/2012
author: Tang W
date: 06/14/2012
journal: Am J Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22703881
trait: Activated partial thromboplastin time
initial_samplesize: 9,240 European ancestry individuals
replication_samplesize: 2611 European ancestry individuals
study:
Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease.


dbdate: 08/08/2012
author: Cipriani V
date: 06/13/2012
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22694956
trait: Age-related macular degeneration
initial_samplesize: 893 European ancestry cases, 2,199 European ancestry controls
replication_samplesize: 1,411 European ancestry cases, 1,431 European ancestry controls
study:
Genome-wide association study of age-related macular degeneration identifies associated variants in the TNXB-FKBPL-NOTCH4 region of chromosome 6p21.3.


dbdate: 08/07/2012
author: Hotaling JM
date: 06/13/2012
journal: J Urol
link: http://www.ncbi.nlm.nih.gov/pubmed/22704111
trait: Erectile dysfunction
study:
Pilot genome-wide association search identifies potential loci for risk of erectile dysfunction in type 1 diabetes using the DCCT/EDIC study cohort.

initial_samplesize:
125 European ancestry Erectile dysfunction cases with Type 1 Diabetes, 403 European ancestry non Erectile dysfunction controls with Type 1 Diabetes


dbdate: 08/14/2012
author: Bergen SE
date: 06/12/2012
journal: Mol Psychiatry
link: http://www.ncbi.nlm.nih.gov/pubmed/22688191
trait: Bipolar disorder
initial_samplesize: 836 European ancestry cases, 2,093 European ancestry controls
study:
Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.


dbdate: 08/07/2012
author: Sinner MF
date: 06/06/2012
journal: Heart Rhythm
link: http://www.ncbi.nlm.nih.gov/pubmed/22683750
trait: Cardiac repolarization
initial_samplesize: 7,482 European ancestry individuals
replication_samplesize: 7,151 European ancestry individuals
study:
A meta-analysis of genome-wide association studies of the electrocardiographic early repolarization pattern.


dbdate: 07/19/2012
author: Han JY
date: 06/05/2012
journal: Pharmacogenomics J
link: http://www.ncbi.nlm.nih.gov/pubmed/22664479
trait: Response to irinotecan in non-small-cell lung cancer
initial_samplesize: 101 non-small-cell lung cancer cases
replication_samplesize: 146 non-small-cell lung cancer cases
study:
A genome-wide association study for irinotecan-related severe toxicities in patients with advanced non-small-cell lung cancer.


dbdate: 08/15/2012
author: Heit JA
date: 06/05/2012
journal: J Thromb Haemost
link: http://www.ncbi.nlm.nih.gov/pubmed/22672568
trait: Venous thromboembolism
initial_samplesize: 1,503 European and other ancestry cases, 1,459 European and other ancestry controls
replication_samplesize: 1,407 Other ancestry cases, 1,418 Other ancestry controls
study:
A genome-wide association study of venous thromboembolism identifies risk variants in chromosomes 1q24.2 and 9q.


dbdate: 07/27/2012
author: Prescott J
date: 06/04/2012
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/22675492
trait: Estradiol levels
initial_samplesize: 1,583 European ancestry females
study:
Genome-wide association study of circulating estradiol, testosterone, and sex hormone-binding globulin in postmenopausal women.


dbdate: 08/15/2012
author: Li R
date: 05/31/2012
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22693459
trait: Male-pattern baldness
initial_samplesize: 3,891 European ancestry cases, 8,915 European ancestry controls
study:
Six novel susceptibility Loci for early-onset androgenetic alopecia and their unexpected association with common diseases.


dbdate: 08/07/2012
author: Perry JR
date: 05/31/2012
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22693455
trait: Type 2 diabetes
initial_samplesize: 2,112 lean type 2 diabetes cases, 4,123 obese type 2 diabetes cases, 54,412 controls
replication_samplesize: 2,881 lean type 2 diabetes cases, 8,702 obese type 2 diabetes cases, 18,957 controls
study:
Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases.


dbdate: 07/19/2012
author: Wang KS
date: 05/31/2012
journal: J Mol Neurosci
link: http://www.ncbi.nlm.nih.gov/pubmed/22648509
trait: Formal thought disorder in schizophrenia
initial_samplesize: 835 European ancestry cases, 2,694 European ancestry controls
study:
PKNOX2 is associated with formal thought disorder in schizophrenia: a meta-analysis of two genome-wide association studies.


dbdate: 07/17/2012
author: Pajewski NM
date: 05/30/2012
journal: Vaccine
link: http://www.ncbi.nlm.nih.gov/pubmed/22658931
trait: Immune response to anthrax vaccine
initial_samplesize: 726 European ancestry individuals
study:
A genome-wide association study of host genetic determinants of the antibody response to Anthrax Vaccine Adsorbed.


dbdate: 07/19/2012
author: Shiffman D
date: 05/30/2012
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/22666496
trait: Response to statin therapy
replication_samplesize: 590 individuals with an event, 4,654 individuals without an event
study:
Genome-wide study of gene variants associated with differential cardiovascular event reduction by pravastatin therapy.

initial_samplesize:
667 European ancestry event individuals, 2,246 European ancestry non-event individuals, 18 African American event individuals, 60 African American non-event individuals, 20 Hispanic event individuals, 65 Hispanic non-event individuals, 6 Asian, Pacific or other ancestry event individuals, 27 Asian, Pacific or other ancestry non-event individuals


dbdate: 07/17/2012
author: Dunlop MG
date: 05/27/2012
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22634755
study: Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk.
trait: Colorectal cancer
initial_samplesize: 8,323 European ancestry cases, 9,457 European ancestry controls
replication_samplesize:
19,513 European ancestry cases, 17,657 European ancestry controls, 1,583 Japanese ancestry cases, 1,898 Japanese ancestry controls


dbdate: 07/17/2012
author: Wei S
date: 05/27/2012
journal: Carcinogenesis
link: http://www.ncbi.nlm.nih.gov/pubmed/22637743
trait: Lung cancer-asbestos exposure interaction
initial_samplesize: 1,154 European ancestry cases, 1,137 European ancestry controls
study:
Genome-wide gene-environment interaction analysis for asbestos exposure in lung cancer susceptibility.


dbdate: 08/07/2012
author: Kennedy RB
date: 05/19/2012
journal: Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22610502
trait: Immune reponse to smallpox (secreted IFN-alpha)
initial_samplesize: Up to 512 European ancestry individuals, up to 199 African American individuals
study:
Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients.


dbdate: 07/31/2012
author: Melville SA
date: 05/15/2012
journal: Ann Neurol
link: http://www.ncbi.nlm.nih.gov/pubmed/22745009
study: Multiple loci influencing hippocampal degeneration identified by genome scan.
trait: Hippocampal atrophy
replication_samplesize: 419 African American Alzheimer disease cases
initial_samplesize:
1149 European ancestry Alzheimer disease cases, 336 European ancestry individuals with mild cognitive impairment, 188 European ancestry controls


dbdate: 07/11/2012
author: Sasayama D
date: 05/15/2012
journal: Pharmacogenomics J
link: http://www.ncbi.nlm.nih.gov/pubmed/22584459
trait: Response to antidepressants
initial_samplesize: 92 Japanese ancestry cases
replication_samplesize: 136 Japanese ancestry cases
study:
Possible association of CUX1 gene polymorphisms with antidepressant response in major depressive disorder.


dbdate: 08/15/2012
author: Manning AK
date: 05/13/2012
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22581228
trait: Fasting glucose-related traits (interaction with BMI)
initial_samplesize: Up to 58,074 European ancestry individuals
replication_samplesize: Up tp 38,422 European ancestry individuals
study:
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.


dbdate: 08/17/2012
author: Fox CS
date: 05/10/2012
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22589738
trait: Subcutaneous adipose tissue
initial_samplesize: 5,560 European ancestry females and 4,997 European ancestry males
study:
Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women.


dbdate: 07/27/2012
author: Castano Betancourt MC
date: 05/07/2012
journal: Proc Natl Acad Sci U S A
link: http://www.ncbi.nlm.nih.gov/pubmed/22566624
trait: Osteoarthritis
initial_samplesize: 6,523 European ancestry individuals
replication_samplesize: 4,442 European ancestry individuals
study:
Genome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritis.


dbdate: 08/09/2012
author: Malhotra AK
date: 05/07/2012
journal: Arch Gen Psychiatry
link: http://www.ncbi.nlm.nih.gov/pubmed/22566560
trait: Antipsychotic drug-induced weight gain
initial_samplesize: 77 European ancestry individuals, 32 African American individuals, 30 Other ancestry individuals
replication_samplesize: 183 European ancestry individuals, 22 African American individuals
study:
Association between common variants near the melanocortin 4 receptor gene and severe antipsychotic drug-induced weight gain.


dbdate: 07/21/2012
author: Turner ST
date: 05/07/2012
journal: Hypertension
link: http://www.ncbi.nlm.nih.gov/pubmed/22566498
trait: Response to angiotensin II receptor blocker therapy
initial_samplesize: 198 European ancestry hypertensive individuals, 193 African American hypertensive individuals
study:
Genomic association analysis identifies multiple loci influencing antihypertensive response to an angiotensin II receptor blocker.


dbdate: 07/10/2012
author: Krintel SB
date: 05/06/2012
journal: Pharmacogenet Genomics
link: http://www.ncbi.nlm.nih.gov/pubmed/22569225
trait: Response to TNF-alpha inhibitors in rheumatoid arthritis
initial_samplesize: 196 European ancestry cases
study:
Investigation of single nucleotide polymorphisms and biological pathways associated with response to TNF&#x003b1; inhibitors in patients with rheumatoid arthritis.


dbdate: 06/20/2012
author: Kenny EE
date: 05/04/2012
journal: Science
link: http://www.ncbi.nlm.nih.gov/pubmed/22556244
study: Melanesian blond hair is caused by an amino acid change in TYRP1.
trait: Hair color
initial_samplesize:
43 Solomon Islander ancestry blond haired individuals, 42 Solomon Islander ancestry dark haired individuals


dbdate: 07/03/2012
author: Kang SJ
date: 05/03/2012
journal: Genes Brain Behav
link: http://www.ncbi.nlm.nih.gov/pubmed/22554406
trait: Electroencephalographic traits in alcoholism
initial_samplesize: 1,560 European ancestry individuals from 117 families
study:
Family-based genome-wide association study of frontal &#x003b8; oscillations identifies potassium channel gene KCNJ6.


dbdate: 06/22/2012
author: Osman W
date: 04/27/2012
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/22558069
trait: Non-albumin protein levels
initial_samplesize: Up to 9,103 Japanese ancestry individuals
replication_samplesize: Up to 1,629 Japanese ancestry individuals
study:
Association of common variants in TNFRSF13B, TNFSF13, and ANXA3 with serum levels of non-albumin protein and immunoglobulin isotypes in Japanese.


dbdate: 06/18/2012
author: Wiggs JL
date: 04/26/2012
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22570617
trait: Glaucoma (primary open-angle)
initial_samplesize: 3,146 European ancestry cases, 3,487 European ancestry controls
study:
Common variants at 9p21 and 8q22 are associated with increased susceptibility to optic nerve degeneration in glaucoma.


dbdate: 06/18/2012
author: Zhao H
date: 04/26/2012
journal: Am J Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22541561
trait: Non-obstructive azoospermia
initial_samplesize: 802 Han Chinese ancestry cases, 1,863 Han Chinese ancestry controls
replication_samplesize: 1,424 Han Chinese ancestry cases, 2,713 Han Chinese ancestry controls
study:
A genome-wide association study reveals that variants within the HLA region are associated with risk for nonobstructive azoospermia.


dbdate: 06/18/2012
author: Rice JP
date: 04/24/2012
journal: Addiction
link: http://www.ncbi.nlm.nih.gov/pubmed/22524403
trait: Nicotine dependence
initial_samplesize: 2,267 European ancestry individuals, 99 Hispanic individuals, 999 African American individuals
replication_samplesize: 835 individuals
study:
CHRNB3 is more strongly associated with Fagerstr&#x000f6;m test for cigarette dependence-based nicotine dependence than cigarettes per day: phenotype definition changes genome-wide association studies results.


dbdate: 06/19/2012
author: Rasmussen-Torvik LJ
date: 04/16/2012
journal: Genet Epidemiol
link: http://www.ncbi.nlm.nih.gov/pubmed/22508271
trait: Fasting plasma glucose
study:
Fasting glucose GWAS candidate region analysis across ethnic groups in the Multiethnic Study of Atherosclerosis (MESA).

initial_samplesize:
2,349 European ancestry individuals, 664 Chinese ancestry individuals, 1,366 African American individuals, 1,171 Hispanic individuals


dbdate: 06/18/2012
author: Rawal R
date: 04/16/2012
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22494929
trait: Thyroid function
initial_samplesize: 3,736 European ancestry individuals
replication_samplesize: 3,727 European ancestry individuals
study:
Meta-analysis of two genome-wide association studies identifies four genetic loci associated with thyroid function.


dbdate: 04/11/2013
author: Estrada K
date: 04/15/2012
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22504420
trait: Bone mineral density
initial_samplesize: Up to 32,961 European and East Asian ancestry individuals
replication_samplesize: Up to 50,933 European and East Asian ancestry individuals
study:
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.


dbdate: 06/21/2012
author: Stein JL
date: 04/15/2012
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22504417
study: Identification of common variants associated with human hippocampal and intracranial volumes.
trait: Brain structure
initial_samplesize: 2,020 European ancestry neuropsychiatric disorder cases, 5,775 European ancestry controls
replication_samplesize:
599 European ancestry neuropsychiatric disorder cases, 11,915 European ancestry controls, 143 European ancestry and African American neuropsychiatric disorder cases, 94 European ancestry and African American controls, 605 Hispanic controls


dbdate: 05/25/2012
author: Jylhava J
date: 04/12/2012
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/22511988
trait: Circulating cell-free DNA
initial_samplesize: 1,841 individuals
study:
A genome-wide association study identifies UGT1A1 as a regulator of serum cell-free DNA in young adults: The Cardiovascular Risk in Young Finns Study.


dbdate: 06/19/2012
author: Wang J
date: 04/10/2012
journal: Pharmacogenomics J
link: http://www.ncbi.nlm.nih.gov/pubmed/22491018
trait: Response to tocilizumab in rheumatoid arthritis
initial_samplesize: 1,157 European and other ancestry rheumatoid arthritis cases
replication_samplesize: 526 European and other ancestry rheumatoid arthritis cases
study:
Genome-wide association analysis implicates the involvement of eight loci with response to tocilizumab for the treatment of rheumatoid arthritis.


dbdate: 07/16/2012
author: Ellinghaus D
date: 04/06/2012
journal: Am J Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22482804
trait: Crohn's disease and psoriasis
study:
Combined analysis of genome-wide association studies for Crohn disease and psoriasis identifies seven shared susceptibility loci.

initial_samplesize:
2,529 European ancestry psoriasis cases, 2,142 European ancestry Crohn's disease cases, 10,460 European ancestry controls

replication_samplesize:
Up to 3,187 European ancestry psoriasis cases, 4,073 European ancestry Crohn's disease cases, 10,100 European ancestry controls


dbdate: 05/11/2012
author: Doumatey AP
date: 04/05/2012
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22492993
trait: C-reactive protein
initial_samplesize: 837 African American individuals
replication_samplesize: 486 West African ancestry individuals
study:
C-reactive protein (CRP) promoter polymorphisms influence circulating CRP levels in a genome-wide association study of African Americans.


dbdate: 05/15/2012
author: Zuo L
date: 04/04/2012
journal: Am J Med Genet B Neuropsychiatr Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22488850
study: Genome-wide search for replicable risk gene regions in alcohol and nicotine co-dependence.
trait: Alcohol and nictotine co-dependence
initial_samplesize:
818 European ancestry cases, 1,396 European ancestry controls, 449 African American cases, 480 African American controls


dbdate: 04/28/2012
author: Boraska V
date: 03/29/2012
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/22479309
trait: Brachial circumference
initial_samplesize: 18,753 European ancestry individuals
replication_samplesize: 3,623 European ancestry individuals
study:
Genome-wide association study to identify common variants associated with brachial circumference: a meta-analysis of 14 cohorts.


dbdate: 05/10/2012
author: Dastani Z
date: 03/29/2012
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22479202
trait: Adiponectin levels
initial_samplesize: 29,347 European ancestry individuals
replication_samplesize: 10,536 European ancestry individuals
study:
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.


dbdate: 04/28/2012
author: Imamura M
date: 03/28/2012
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22456796
trait: Type 2 diabetes
initial_samplesize: 4,470 Japanese ancestry cases, 3,071 Japanese ancestry controls
replication_samplesize: 7,605 Japanese ancestry cases, 3,534 Japanese ancestry controls
study:
A single-nucleotide polymorphism in ANK1 is associated with susceptibility to type 2 diabetes in Japanese populations.


dbdate: 04/28/2012
author: Kim HC
date: 03/27/2012
journal: Breast Cancer Res
link: http://www.ncbi.nlm.nih.gov/pubmed/22452962
trait: Breast cancer
initial_samplesize: 2,273 Korean ancestry cases, 2,052 Korean ancestry controls
replication_samplesize: 4,049 Korean ancestry cases, 3,845 Korean ancestry controls
study:
A genome-wide association study identifies a breast cancer risk variant in ERBB4 at 2q34: results from the Seoul Breast Cancer Study.


dbdate: 04/25/2012
author: Lee YC
date: 03/25/2012
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22446961
trait: Kawasaki disease
initial_samplesize: 622 Taiwanese Han Chinese ancestry cases, 1,107 Taiwanese Han Chinese ancestry controls
replication_samplesize: 261 Taiwanese Han Chinese ancestry cases, 550 Taiwanese Han Chinese ancestry controls
study:
Two new susceptibility loci for Kawasaki disease identified through genome-wide association analysis.


dbdate: 04/27/2012
author: Okada Y
date: 03/25/2012
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22446963
trait: Rheumatoid arthritis
initial_samplesize: 4,074 Japanese ancestry cases, 16,891 Japanese ancestry controls
replication_samplesize: 5,277 Japanese ancestry cases, 21,684 Japanese ancestry controls
study:
Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population.


dbdate: 04/20/2012
author: Kurose K
date: 03/23/2012
journal: Psychiatry Res
link: http://www.ncbi.nlm.nih.gov/pubmed/22445761
trait: Sexual dysfunction (SSRI/SNRI-related)
initial_samplesize: 201 Japanese ancestry individuals
study:
Genome-wide association study of SSRI/SNRI-induced sexual dysfunction in a Japanese cohort with major depression.


dbdate: 04/06/2012
author: Osman W
date: 03/22/2012
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22419738
trait: Glaucoma (primary open-angle)
initial_samplesize: 1,394 Japanese ancestry cases, 6,599 Japanese ancestry controls
replication_samplesize: 1,802 Japanese ancestry cases, 7,212 Japanese ancestry controls
study:
A genome-wide association study in the Japanese population confirms 9p21 and 14q23 as susceptibility loci for primary open angle glaucoma.


dbdate: 06/18/2012
author: Major JM
date: 03/21/2012
journal: J Nutr
link: http://www.ncbi.nlm.nih.gov/pubmed/22437554
trait: Response to Vitamin E supplementation
initial_samplesize: 2,112 European ancestry individuals
study:
Genome-wide association study identifies three common variants associated with serologic response to vitamin E supplementation in men.


dbdate: 04/18/2012
author: Wang KS
date: 03/16/2012
journal: Gene
link: http://www.ncbi.nlm.nih.gov/pubmed/22446040
trait: Body mass index
initial_samplesize: 5,218 European ancestry individuals
replication_samplesize: 762 European ancestry individuals
study:
A novel locus for body mass index on 5p15.2: a meta-analysis of two genome-wide association studies.


dbdate: 05/18/2012
author: Lill CM
date: 03/15/2012
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22438815
trait: Parkinson's disease
initial_samplesize: 2,197 Other ancestry cases, 2,061 Other ancestry controls
replication_samplesize: Up to 98,080 individuals of European and Asian ancestry
study:
Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database.


dbdate: 04/18/2012
author: Lopez LM
date: 03/15/2012
journal: Neurobiol Aging
link: http://www.ncbi.nlm.nih.gov/pubmed/22425255
trait: White matter integrity
initial_samplesize: 535 European ancestry individuals
study:
A genome-wide search for genetic influences and biological pathways related to the brain's white matter integrity.


dbdate: 04/06/2012
author: Athanasiu L
date: 03/12/2012
journal: Psychiatry Res
link: http://www.ncbi.nlm.nih.gov/pubmed/22417934
trait: Body mass index and cholesterol (psychopharmacological treatment)
study:
Genome-wide association study identifies genetic loci associated with body mass index and high density lipoprotein-cholesterol levels during psychopharmacological treatment - a cross-sectional naturalistic study.

initial_samplesize:
283 European ancestry schizophrenia cases, 213 European ancestry bipolar disorder cases, 98 European ancestry psychosis cases


dbdate: 04/03/2012
author: Nakano M
date: 03/12/2012
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/22428042
trait: Glaucoma (primary open-angle)
initial_samplesize: 833 Japanese ancestry cases, 686 Japanese ancestry controls
replication_samplesize: 411 Japanese ancestry cases, 289 Japanese ancestry controls
study:
Common variants in CDKN2B-AS1 associated with optic-nerve vulnerability of glaucoma identified by genome-wide association studies in Japanese.


dbdate: 03/30/2012
author: Jongjaroenprasert W
date: 03/08/2012
journal: J Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22399142
trait: Thyrotoxic hypokalemic periodic paralysis
initial_samplesize: 78 Thai ancestry cases, 74 Thai ancestry controls
replication_samplesize: 28 Thai ancestry cases, 48 Thai ancestry controls
study:
A genome-wide association study identifies novel susceptibility genetic variation for thyrotoxic hypokalemic periodic paralysis.


dbdate: 04/03/2012
author: Qayyum R
date: 03/08/2012
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22423221
trait: Mean platelet volume
initial_samplesize: 16,388 African American individuals
study:
A meta-analysis and genome-wide association study of platelet count and mean platelet volume in african americans.


dbdate: 04/03/2012
author: Kristiansson K
date: 03/07/2012
journal: Circ Cardiovasc Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22399527
trait: Metabolic syndrome
initial_samplesize: 2,637 European ancestry cases, 7,927 European ancestry controls
study:
Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.


dbdate: 03/27/2012
author: Froguel P
date: 03/05/2012
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/22403646
trait: Haptoglobin levels
initial_samplesize: 631 European ancestry children
replication_samplesize: 2,957 European ancestry family members, 1,434 European ancestry individuals
study:
A genome-wide association study identifies rs2000999 as a strong genetic determinant of circulating haptoglobin levels.


dbdate: 03/20/2012
author: Tanikawa C
date: 03/04/2012
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22387998
trait: Duodenal ulcer
initial_samplesize: 1,043 Japanese ancestry cases, 21,694 Japanese ancestry controls
replication_samplesize: 5,992 Japanese ancestry cases, 3,629 Japanese ancestry controls
study:
A genome-wide association study identifies two susceptibility loci for duodenal ulcer in the Japanese population.


dbdate: 04/03/2012
author: McCormack M
date: 03/01/2012
journal: Pharmacogenomics
link: http://www.ncbi.nlm.nih.gov/pubmed/22379998
trait: Adverse response to lamotrigine and phenytoin
study:
Genome-wide mapping for clinically relevant predictors of lamotrigine- and phenytoin-induced hypersensitivity reactions.

initial_samplesize:
34 European ancestry lamotrigine-induced hypersensitivity cases, 42 European ancestry phenytoin-induced hypersensitivity cases, 1,296 European ancestry controls


dbdate: 03/20/2012
author: Urabe Y
date: 03/01/2012
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22396660
trait: Nephrolithiasis
initial_samplesize: 904 Japanese ancestry cases, 7,471 Japanese ancestry controls
replication_samplesize: 4,892 Japanese ancestry cases, 9,873 Japanese ancestry controls
study:
A genome-wide association study of nephrolithiasis in the Japanese population identifies novel susceptible Loci at 5q35.3, 7p14.3, and 13q14.1.


dbdate: 03/17/2012
author: Deshmukh HA
date: 02/24/2012
journal: J Lipid Res
link: http://www.ncbi.nlm.nih.gov/pubmed/22368281
trait: Response to statin therapy
initial_samplesize: 2,702 European ancestry individuals
replication_samplesize: 2,550 European ancestry individuals
study:
Genome-wide association study of genetic determinants of LDL-c response to atorvastatin therapy: importance of Lp(a).


dbdate: 03/20/2012
author: Guo Y
date: 02/24/2012
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/22384028
trait: Hypertension
initial_samplesize: 315 Hong Kong Chinese ancestry individuals from 111 families
study:
A genome-wide linkage and association scan reveals novel loci for hypertension and blood pressure traits.


dbdate: 03/17/2012
author: Lin X
date: 02/24/2012
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22367966
trait: Vitamin B12 levels
initial_samplesize: 1,999 Han Chinese ancestry individuals
replication_samplesize: 1,496 Chinese ancestry individuals
study:
Genome-wide association study identifies novel loci associated with serum level of vitamin B12 in Chinese men.


dbdate: 03/17/2012
author: Long J
date: 02/23/2012
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22383897
trait: Breast cancer
initial_samplesize: 2,918 Chinese ancestry cases, 2,324 Chinese ancestry controls
replication_samplesize: up to 16,173 East Asian ancestry cases, up to 18,282 East Asian ancestry controls
study:
Genome-wide association study in east Asians identifies novel susceptibility loci for breast cancer.


dbdate: 04/28/2012
author: Clark PJ
date: 02/22/2012
journal: J Viral Hepat
link: http://www.ncbi.nlm.nih.gov/pubmed/22497812
trait: Lipid levels in hepatitis C treatment
initial_samplesize: 1,017 European ancestry cases, 207 African American cases, 95 Hispanic cases
study:
Interleukin 28B polymorphisms are the only common genetic variants associated with low-density lipoprotein cholesterol (LDL-C) in genotype-1 chronic hepatitis C and determine the association between LDL-C and treatment response.


dbdate: 03/30/2012
author: Greenwood TA
date: 02/22/2012
journal: Biol Psychiatry
link: http://www.ncbi.nlm.nih.gov/pubmed/22365631
trait: Temperament (bipolar disorder)
initial_samplesize: 1,263 European ancestry cases, 1,434 European ancestry controls
study:
Genome-wide association study of temperament in bipolar disorder reveals significant associations with three novel Loci.


dbdate: 03/30/2012
author: Thompson SD
date: 02/21/2012
journal: Arthritis Rheum
link: http://www.ncbi.nlm.nih.gov/pubmed/22354554
trait: Arthritis (juvenile idiopathic)
initial_samplesize: 814 European ancestry cases, 658 European ancestry controls, 2,400 controls
replication_samplesize: 1,744 European ancestry cases, 7,010 European ancestry controls
study:
Genome-wide association analysis of juvenile idiopathic arthritis identifies a new susceptibility locus at chromosomal region 3q13.


dbdate: 03/19/2012
author: Wen W
date: 02/19/2012
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22344219
study: Meta-analysis identifies common variants associated with body mass index in east Asians.
trait: Body mass index
replication_samplesize: 53,215 East Asian ancestry results, 2,118 Malay ancestry individuals
initial_samplesize:
22,762 East Asian ancestry individuals, 2,522 Malay ancestry individuals, 2,431 Chinese, Malay and Asian Indian ancestry individuals


dbdate: 03/13/2012
author: Bakken TE
date: 02/16/2012
journal: Proc Natl Acad Sci U S A
link: http://www.ncbi.nlm.nih.gov/pubmed/22343285
trait: Cortical structure
initial_samplesize: 421 European ancestry individuals
replication_samplesize: 760 European ancestry individuals
study:
Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans.


dbdate: 03/27/2012
author: Demirkan A
date: 02/16/2012
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22359512
trait: Phospholipid levels (plasma)
initial_samplesize: 4,034 European ancestry individuals
study:
Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations.


dbdate: 03/13/2012
author: Paternoster L
date: 02/16/2012
journal: Am J Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22341974
trait: Facial morphology
initial_samplesize: 2,185 European ancestry adolescents
replication_samplesize: 1,622 European ancestry adolescents
study:
Genome-wide association study of three-dimensional facial morphology identifies a variant in PAX3 associated with nasion position.


dbdate: 03/14/2012
author: Chasman DI
date: 02/13/2012
journal: Circ Cardiovasc Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22331829
trait: Response to statin therapy (LDL-C)
initial_samplesize: 6,989 European ancestry individuals
study:
Genetic determinants of statin-induced low-density lipoprotein cholesterol reduction: the Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER) trial.


dbdate: 03/08/2012
author: Cha PC
date: 02/09/2012
journal: J Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22318345
trait: Gallbladder cancer
initial_samplesize: 41 Japanese ancestry cases, 866 Japanese ancestry controls
replication_samplesize: 30 Japanese ancestry cases, 898 Japanese ancestry controls
study:
A genome-wide association study identifies SNP in DCC is associated with gallbladder cancer in the Japanese population.


dbdate: 03/03/2012
author: Kim SJ
date: 02/09/2012
journal: Circ J
link: http://www.ncbi.nlm.nih.gov/pubmed/22322875
trait: Hypertension risk in short sleep duration
initial_samplesize: 4,965 Korean ancestry individuals
study:
Genetic association of short sleep duration with hypertension incidence--a 6-year follow-up in the Korean genome and epidemiology study.


dbdate: 03/08/2012
author: Davies RW
date: 02/07/2012
journal: Circ Cardiovasc Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22319020
trait: Coronary heart disease
initial_samplesize: 7,123 European ancestry cases, 6,826 European ancestry controls
replication_samplesize: 5,211 European ancestry cases, 5,821 European ancestry controls
study:
A genome-wide association study for coronary artery disease identifies a novel susceptibility locus in the major histocompatibility complex.


dbdate: 03/13/2012
author: Man M
date: 02/07/2012
journal: Pharmacogenomics J
link: http://www.ncbi.nlm.nih.gov/pubmed/22310353
trait: Treatment response for severe sepsis
initial_samplesize: 1,446 individuals
study:
Beyond single-marker analyses: mining whole genome scans for insights into treatment responses in severe sepsis.


dbdate: 03/09/2012
author: Bellenguez C
date: 02/05/2012
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22306652
trait: Stroke
initial_samplesize: 3,548 European ancestry cases, 5,972 European ancestry controls
replication_samplesize: 6,594 European ancestry cases, 34,864 European ancestry controls
study:
Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke.


dbdate: 03/09/2012
author: Thye T
date: 02/05/2012
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22306650
study: Common variants at 11p13 are associated with susceptibility to tuberculosis.
trait: Tuberculosis
initial_samplesize: 1,329 African ancestry cases, 1,847 African ancestry controls
replication_samplesize:
2,024 African ancestry cases, 5,154 African ancestry controls, 1,025 Indonesian ancestry cases, 983 Indonesian ancestry controls, 4,441 European ancestry cases, 5,874 European ancestry controls


dbdate: 03/10/2012
author: Huang J
date: 02/01/2012
journal: Eur J Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22293688
trait: Crohn's disease
initial_samplesize: 16,179 European ancestry individuals
study:
1000 Genomes-based imputation identifies novel and refined associations for the Wellcome Trust Case Control Consortium phase 1 Data.


dbdate: 02/25/2012
author: Ryu J
date: 01/30/2012
journal: Hum Mutat
link: http://www.ncbi.nlm.nih.gov/pubmed/22290723
trait: Glycated hemoglobin levels
initial_samplesize: 4,275 Korean ancestry individuals
replication_samplesize: 3,782 Korean ancestry individuals
study:
Association of glycosylated hemoglobin with the gene encoding CDKAL1 in the Korean Association Resource (KARE) study.


dbdate: 03/23/2012
author: Kiyotani K
date: 01/29/2012
journal: Pharmacogenet Genomics
link: http://www.ncbi.nlm.nih.gov/pubmed/22293537
trait: Response to gemcitabine in pancreatic cancer
initial_samplesize: 21 Japanese ancestry adverse reaction cases, 58 Japanese ancestry non-adverse reaction individuals
replication_samplesize: 33 Japanese ancestry adverse reaction cases, 62 Japanese ancestry non-adverse reaction individuals
study:
A genome-wide association study identifies four genetic markers for hematological toxicities in cancer patients receiving gemcitabine therapy.


dbdate: 02/25/2012
author: Cusanovich DA
date: 01/27/2012
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22286170
trait: Lymphocyte counts
initial_samplesize: 462 Hutterite individuals
study:
The combination of a genome-wide association study of lymphocyte count and analysis of gene expression data reveals novel asthma candidate genes.


dbdate: 02/23/2012
author: Low SK
date: 01/27/2012
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22286173
trait: Intracranial aneurysm
initial_samplesize: 1,383 Japanese ancestry cases, 5,484 Japanese ancestry controls
replication_samplesize: 1,048 Japanese ancestry cases, 7,212 Japanese ancestry controls
study:
Genome-wide association study for intracranial aneurysm in the Japanese population identifies three candidate susceptible loci and a functional genetic variant at EDNRA.


dbdate: 02/23/2012
author: Urayama KY
date: 01/27/2012
journal: J Natl Cancer Inst
link: http://www.ncbi.nlm.nih.gov/pubmed/22286212
trait: Hodgkin's lymphoma
initial_samplesize: 1,200 European ancestry cases, 6,417 European ancestry controls
replication_samplesize: 563 European ancestry cases, 613 European ancestry controls
study:
Genome-wide association study of classical Hodgkin lymphoma and Epstein-Barr virus status-defined subgroups.


dbdate: 02/22/2012
author: Naitza S
date: 01/26/2012
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22291609
trait: Inflammatory biomarkers
initial_samplesize: 4,694 European ancestry individuals
replication_samplesize: 1,392 European ancestry individuals
study:
A genome-wide association scan on the levels of markers of inflammation in Sardinians reveals associations that underpin its complex regulation.


dbdate: 02/21/2012
author: Okada Y
date: 01/26/2012
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22291604
trait: Systemic lupus erythematosus
initial_samplesize: 891 Japanese ancestry cases, 3,384 Japanese ancestry controls
replication_samplesize: 1,387 Japanese ancestry cases, 28,564 Japanese ancestry controls
study:
A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese.


dbdate: 02/10/2012
author: Stolk L
date: 01/22/2012
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22267201
trait: Menopause (age at onset)
initial_samplesize: 38,968 European ancestry females
replication_samplesize: Up to 14,435 European ancestry females
study:
Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways.


dbdate: 03/20/2012
author: Zhang CK
date: 01/19/2012
journal: Am J Hematol
link: http://www.ncbi.nlm.nih.gov/pubmed/22388998
trait: Gaucher disease severity
initial_samplesize: 139 Ashkenazi Jewish cases
study:
Genome-wide association study of N370S homozygous Gaucher disease reveals the candidacy of CLN8 gene as a genetic modifier contributing to extreme phenotypic variation.


dbdate: 04/25/2012
author: Oudot-Mellakh T
date: 01/16/2012
journal: Br J Haematol
link: http://www.ncbi.nlm.nih.gov/pubmed/22443383
trait: Hemostatic factors and hematological phenotypes
initial_samplesize: 951 European ancestry individuals
study:
Genome wide association study for plasma levels of natural anticoagulant inhibitors and protein C anticoagulant pathway: the MARTHA project.


dbdate: 02/09/2012
author: Murray SS
date: 01/11/2012
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/22247754
trait: Life threatening arrhythmia
initial_samplesize: 607 European ancestry cases, 297 European ancestry controls
study:
Genome-wide association of implantable cardioverter-defibrillator activation with life-threatening arrhythmias.


dbdate: 02/08/2012
author: Karns R
date: 01/09/2012
journal: Ann Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22229870
trait: Uric acid levels
initial_samplesize: 1,300 European ancestry individuals
study:
Genome-wide association of serum uric acid concentration: replication of sequence variants in an island population of the Adriatic coast of Croatia.


dbdate: 03/10/2012
author: Aslibekyan S
date: 01/05/2012
journal: Pharmacogenet Genomics
link: http://www.ncbi.nlm.nih.gov/pubmed/22228203
trait: Inflammatory biomarkers
initial_samplesize: 1,092 European ancestry individuals
study:
A genome-wide association study of inflammatory biomarker changes in response to fenofibrate treatment in the Genetics of Lipid Lowering Drug and Diet Network.


dbdate: 03/31/2012
author: Tao S
date: 01/04/2012
journal: Carcinogenesis
link: http://www.ncbi.nlm.nih.gov/pubmed/22219177
trait: Prostate cancer (gene x gene interaction)
initial_samplesize: 4,723 European ancestry cases, 4,792 European ancestry controls
study:
A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.


dbdate: 10/16/2012
author: O'Donnell PH
date: 01/03/2012
journal: Cancer
link: http://www.ncbi.nlm.nih.gov/pubmed/22864933
study: Identification of novel germline polymorphisms governing capecitabine sensitivity.
trait: Capecitabine sensitivity
initial_samplesize:
Up to 84 East Asian ancestry lymphoblastoid cell lines, up to 164 European ancestry lymphoblastoid cell lines, up to 173 African ancestry lymphoblastoid cell lines, up to 82 African American lymphoblastoid cell lines


dbdate: 01/20/2012
author: Mead S
date: 12/30/2011
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22210626
trait: Prion diseases
study:
Genome-wide association study in multiple human prion diseases suggests genetic risk factors additional to PRNP.

initial_samplesize:
1,281 European ancestry cases, 6,015 European ancestry controls, 290 Papua New Guinea cases, 286 Papua New Guinea controls.


dbdate: 01/10/2012
author: Tan A
date: 12/30/2011
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22171074
trait: Triglycerides
initial_samplesize: 1,999 Chinese ancestry individuals
replication_samplesize: 1,496 Chinese ancestry individuals.
study:
A genome-wide association and gene-environment interaction study for serum triglycerides levels in a healthy Chinese male population.


dbdate: 01/19/2012
author: Hu Z
date: 12/25/2011
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22197933
trait: Non-obstructive azoospermia
initial_samplesize: 981 Chinese ancestry cases, 1,657 Chinese ancestry controls.
replication_samplesize: 1,946 Chinese ancestry cases, 4,077 Chinese ancestry controls.
study:
A genome-wide association study in Chinese men identifies three risk loci for non-obstructive azoospermia.


dbdate: 01/28/2012
author: Paternoster L
date: 12/25/2011
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22197932
trait: Atopic dermatitis
initial_samplesize: 5,606 European ancestry cases, 20,565 European ancestry controls
replication_samplesize: 5,419 European ancestry cases, 19,833 European ancestry controls
study:
Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis.


dbdate: 01/24/2012
author: Yu XQ
date: 12/25/2011
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22197929
trait: IgA nephropathy
initial_samplesize: 1,434 Chinese ancestry cases, 4,270 Chinese ancestry controls.
replication_samplesize: 2,703 Chinese ancestry cases, 3,464 Chinese ancestry controls.
study:
A genome-wide association study in Han Chinese identifies multiple susceptibility loci for IgA nephropathy.


dbdate: 01/27/2012
author: Murabito JM
date: 12/23/2011
journal: Circ Cardiovasc Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22199011
trait: Ankle-brachial index
initial_samplesize: 41,692 European ancestry individuals
replication_samplesize: 16,717 European ancestry individuals
study:
Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies.


dbdate: 01/27/2012
author: Chen DT
date: 12/20/2011
journal: Mol Psychiatry
link: http://www.ncbi.nlm.nih.gov/pubmed/22182935
trait: Bipolar disorder
replication_samplesize: 1,115 European ancestry cases, 2,728 European ancestry controls
study:
Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder.

initial_samplesize:
5,568 European ancestry cases, 7,187 European ancestry controls, 1,000 Taiwanese cases, 1,000 Taiwanese controls


dbdate: 01/14/2012
author: Kiyotani K
date: 12/16/2011
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22180457
trait: Response to tamoxifen in breast cancer
initial_samplesize: 240 Japanese ancestry cases
replication_samplesize: 222 Japanese ancestry cases
study:
A genome-wide association study identifies locus at 10q22 associated with clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients in Japanese.


dbdate: 01/11/2012
author: Rankinen T
date: 12/15/2011
journal: J Appl Physiol (1985)
link: http://www.ncbi.nlm.nih.gov/pubmed/22174390
trait: Heart rate variability traits
initial_samplesize: 472 European ancestry individuals from 99 families
study:
Heritability of submaximal exercise heart rate response to exercise training is accounted for by nine SNPs.


dbdate: 01/31/2012
author: Lingappa JR
date: 12/12/2011
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/22174851
trait: HIV-1 susceptibility
initial_samplesize: 798 African ancestry
study:
Genomewide association study for determinants of HIV-1 acquisition and viral set point in HIV-1 serodiscordant couples with quantified virus exposure.


dbdate: 01/18/2012
author: Cho YS
date: 12/11/2011
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22158537
trait: Type 2 diabetes
study:
Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians.

initial_samplesize:
4,026 Chinese ancestry cases, 1,042 Korean ancestry cases, 794 Malaysian ancestry cases, 931 Japanese ancestry cases, 159 Filipino ancestry cases, 4,654 Chinese ancestry controls, 2,943 Korean ancestry controls, 1,240 Malaysian ancestry controls, 1,404 Japanese ancestry controls, 1,624 Filipino ancestry controls.

replication_samplesize:
9,723 Japanese ancestry cases, 1,815 Korean ancestry cases, 6,589 Chinese ancestry cases, 8,974 Japanese ancestry controls, 2,066 Korean ancestry controls, Chinese ancestry controls.


dbdate: 01/18/2012
author: Wu C
date: 12/11/2011
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22158540
trait: Pancreatic cancer
initial_samplesize: 981 Chinese ancestry cases, 1,991 Chinese ancestry contorls.
replication_samplesize: 2,603 Chinese ancestry cases, 2,877 Chinese ancestry controls.
study:
Genome-wide association study identifies five loci associated with susceptibility to pancreatic cancer in Chinese populations.


dbdate: 01/06/2012
author: Innocenti F
date: 12/05/2011
journal: Clin Cancer Res
link: http://www.ncbi.nlm.nih.gov/pubmed/22142827
trait: Response to gemcitabine in pancreatic cancer
initial_samplesize: 294 European ancestry cases
study:
A genome-wide association study of overall survival in pancreatic cancer patients treated with gemcitabine in CALGB 80303.


dbdate: 01/06/2012
author: O'Donnell CJ
date: 12/05/2011
journal: Circulation
link: http://www.ncbi.nlm.nih.gov/pubmed/22144573
trait: Coronary artery calcification
initial_samplesize: 9,961 European ancestry individuals
replication_samplesize: 6,032 European ancestry individuals
study:
Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction.


dbdate: 01/04/2012
author: Lin Z
date: 12/04/2011
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22138694
trait: Ankylosing spondylitis
initial_samplesize: 1,837 Han Chinese cases, 4,231 Han Chinese controls
replication_samplesize: 2,100 Han Chinese cases, 3,496 Han Chinese controls
study:
A genome-wide association study in Han Chinese identifies new susceptibility loci for ankylosing spondylitis.


dbdate: 12/24/2011
author: Fan Q
date: 12/01/2011
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22144915
trait: Corneal astigmatism
study:
Genome-wide meta-analysis of five Asian cohorts identifies PDGFRA as a susceptibility locus for corneal astigmatism.

initial_samplesize:
1,231 Chinese ancestry cases, 785 Chinese ancestry controls, 1,018 Malaysian ancestry cases, 1,220 Malaysian ancestry controls

replication_samplesize:
825 Indian ancestry cases, 1,314 Indian ancestry controls, 760 Chinese ancestry cases, 169 Chinese ancestry controls, 1,191 Chinese ancestry individuals from 397 parent-trios


dbdate: 08/21/2013
author: Irvin MR
date: 12/01/2011
journal: Pharmacogenet Genomics
link: http://www.ncbi.nlm.nih.gov/pubmed/21897333
trait: Fat distribution (HIV)
initial_samplesize: 192 European ancestry male cases
study:
Genes linked to energy metabolism and immunoregulatory mechanisms are associated with subcutaneous adipose tissue distribution in HIV-infected men.


dbdate: 01/11/2012
author: Nam RK
date: 12/01/2011
journal: Cancer Biol Ther
link: http://www.ncbi.nlm.nih.gov/pubmed/22130093
trait: Prostate cancer
initial_samplesize: 316 cases, 229 controls
study:
New variants at 10q26 and 15q21 are associated with aggressive prostate cancer in a genome-wide association study from a prostate biopsy screening cohort.

replication_samplesize:
55 Asian ancestry cases, 1,382 European ancestry cases, 184 African American ancestry cases, 42 Other ancestry cases, 134 Asian ancestry controls, 1,428 European ancestry controls, 127 African American ancestry controls, 87 Other ancestry controls


dbdate: 12/20/2011
author: LeBlanc M
date: 11/28/2011
journal: J Psychiatr Res
link: http://www.ncbi.nlm.nih.gov/pubmed/22126837
trait: Cognitive function
study:
Genome-wide study identifies PTPRO and WDR72 and FOXQ1-SUMO1P1 interaction associated with neurocognitive function.

initial_samplesize:
190 European ancestry schizophrenia cases, 157 European ancestry  bipolar disorder cases, 353 European ancestry controls


dbdate: 12/20/2011
author: Guo Y
date: 11/24/2011
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22116939
trait: Epilepsy
initial_samplesize: 504 Han Chinese cases, 2,947 Han Chinese controls
replication_samplesize: 583 Han Chinese cases, 497 Han Chinese controls
study:
Two-stage genome-wide association study identifies variants in CAMSAP1L1 as susceptibility loci for epilepsy in Chinese.


dbdate: 01/11/2012
author: Schuh-Huerta SM
date: 11/24/2011
journal: Hum Reprod
link: http://www.ncbi.nlm.nih.gov/pubmed/22116950
trait: Ovarian reserve
initial_samplesize: 232 European ancestry women, 200 African American ancestry women
study:
Genetic variants and environmental factors associated with hormonal markers of ovarian reserve in Caucasian and African American women.


dbdate: 12/17/2011
author: Kho AN
date: 11/19/2011
journal: J Am Med Inform Assoc
link: http://www.ncbi.nlm.nih.gov/pubmed/22101970
trait: Type 2 diabetes
study:
Use of diverse electronic medical record systems to identify genetic risk for type 2 diabetes within a genome-wide association study.

initial_samplesize:
2,413 European ancestry cases, 810 African American cases, 2,392 European ancestry controls, 873 African American controls


dbdate: 12/20/2011
author: Lange CM
date: 11/16/2011
journal: Hepatology
link: http://www.ncbi.nlm.nih.gov/pubmed/22095909
trait: Response to hepatitis C treatment
initial_samplesize: 707 European ancestry cases
study:
Serum ferritin levels are associated with a distinct phenotype of chronic hepatitis C poorly responding to pegylated interferon-alpha and ribavirin therapy.


dbdate: 12/17/2011
author: Khor CC
date: 11/13/2011
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22081228
study: Genome-wide association study identifies FCGR2A as a susceptibility locus for Kawasaki disease.
trait: Kawasaki disease
initial_samplesize: 405 European ancestry cases, 6,252 European ancestry controls
replication_samplesize:
1815 European ancestry individuals and 405 non-European ancestry individuals from 740 trios, 139 additional discordant European ancestry siblings, 1,028 East Asian ancestry cases, 1,512 East Asian ancestry controls


dbdate: 01/06/2012
author: Ellinghaus E
date: 11/11/2011
journal: Leukemia
link: http://www.ncbi.nlm.nih.gov/pubmed/22076464
trait: Acute lymphoblastic leukemia (childhood)
initial_samplesize: 419 European ancestry cases, 474 European ancestry controls
replication_samplesize: Up to 1,277 European ancestry cases and 3,061 European ancestry controls
study:
Identification of germline susceptibility loci in ETV6-RUNX1-rearranged childhood acute lymphoblastic leukemia.


dbdate: 12/03/2011
author: Mitchell GF
date: 11/08/2011
journal: Circ Cardiovasc Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22068335
trait: Aortic stiffness
initial_samplesize: 20,634 European ancestry individuals
replication_samplesize: 5,306 European ancestry individuals
study:
Common genetic variation in the 3'-BCL11B gene desert is associated with carotid-femoral pulse wave velocity and excess cardiovascular disease risk: the AortaGen Consortium.


dbdate: 12/14/2011
author: Morisaki H
date: 11/07/2011
journal: Hum Mutat
link: http://www.ncbi.nlm.nih.gov/pubmed/22065538
trait: Adiponectin levels
initial_samplesize: 3,310 Japanese ancestry individuals
study:
CDH13 gene coding T-cadherin influences variations in plasma adiponectin levels in the Japanese population.


dbdate: 12/14/2011
author: Sun L
date: 11/07/2011
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/22087292
trait: Femoral neck bone geometry
initial_samplesize: 1,627 Han Chinese individuals
replication_samplesize: 2,286 European ancestry individuals
study:
Bivariate genome-wide association analyses of femoral neck bone geometry and appendicular lean mass.


dbdate: 12/03/2011
author: Bown MJ
date: 11/04/2011
journal: Am J Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22055160
trait: Abdominal aortic aneurysm
initial_samplesize: 1,866 cases, 5,435 controls
replication_samplesize: 4,362 cases, 43,747 controls
study:
Abdominal aortic aneurysm is associated with a variant in low-density lipoprotein receptor-related protein 1.


dbdate: 12/03/2011
author: Foster MC
date: 11/01/2011
journal: BMC Med Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22044751
trait: Renal sinus fat
initial_samplesize: 2,809 European ancestry individuals
study:
Heritability and genome-wide association analysis of renal sinus fat accumulation in the Framingham Heart Study.


dbdate: 12/08/2011
author: Middelberg RP
date: 11/01/2011
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22010049
trait: Gamma gluatamyl transferase levels
initial_samplesize: 12,526 European ancestry individuals
study:
Loci affecting gamma-glutamyl transferase in adults and adolescents show age &#x000d7; SNP interaction and cardiometabolic disease associations.


dbdate: 12/01/2011
author: Ramasamy A
date: 11/01/2011
journal: J Allergy Clin Immunol
link: http://www.ncbi.nlm.nih.gov/pubmed/22036096
trait: Allergic rhinitis
initial_samplesize: 3,933 European ancestry cases, 8,965 European ancestry controls
study:
A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order.


dbdate: 12/16/2011
author: Crosslin DR
date: 10/30/2011
journal: Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22037903
trait: White blood cell count
study:
Genetic variants associated with the white blood cell count in 13,923 subjects in the eMERGE Network.

initial_samplesize:
62 American Indian or Alaska Native ancestry individuals, 158 Asian ancestry individuals, 3,272 African American ancestry individuals, 114 other ancestry individuals, 23,244 European ancestry individuals, 996 unknown ancestry individuals


dbdate: 11/24/2011
author: Haiman CA
date: 10/30/2011
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22037553
trait: Breast cancer
replication_samplesize: 2,222 European ancestry cases, 16,363 European ancestry controls
study:
A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor-negative breast cancer.

initial_samplesize:
1,004 African ancestry cases, 2,745 African ancestry controls,1,718 European ancestry cases, 3,670 European ancestry controls


dbdate: 12/02/2011
author: Shi Y
date: 10/30/2011
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22037551
trait: Gastric cancer
initial_samplesize: 1,006 Chinese ancestry cases, 2,273 Chinese ancestry controls
replication_samplesize: 3,288 Chinese ancestry cases, 3,609 Chinese ancestry controls
study:
A genome-wide association study identifies new susceptibility loci for non-cardia gastric cancer at 3q13.31 and 5p13.1.


dbdate: 12/02/2011
author: Yue WH
date: 10/30/2011
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22037552
trait: Schizophrenia
initial_samplesize: 746 Chinese ancestry cases, 1,599 Chinese ancestry controls
replication_samplesize: 4,027 Chinese ancestry cases, 5,603 Chinese ancestry controls
study:
Genome-wide association study identifies a susceptibility locus for schizophrenia in Han Chinese at 11p11.2.


dbdate: 12/13/2011
author: Brockschmidt FF
date: 10/27/2011
journal: Br J Dermatol
link: http://www.ncbi.nlm.nih.gov/pubmed/22032556
trait: Male-pattern baldness
initial_samplesize: 581 European ancestry male cases, 617 European ancestry male controls
replication_samplesize: 461 European ancestry male cases, 151 European ancestry male controls
study:
Susceptibility variants on chromosome 7p21.1 suggest HDAC9 as a new candidate gene for male-pattern baldness.


dbdate: 11/24/2011
author: Takahashi Y
date: 10/23/2011
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22019779
trait: Scoliosis
initial_samplesize: 1,033 Japanese ancestry adolescent female cases, 1,473 Japanese ancestry female controls
replication_samplesize: 326 Japanese ancestry adolescent female cases, 9,823 Japanese ancestry female controls
study:
A genome-wide association study identifies common variants near LBX1 associated with adolescent idiopathic scoliosis.


dbdate: 11/25/2011
author: Carty CL
date: 10/21/2011
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22021425
trait: Height
initial_samplesize: 8,149 African American ancestry women
replication_samplesize: Up to 20,809 African American ancestry and African ancestry individuals
study:
Genome-wide association study of body height in African Americans: the Women's Health Initiative SNP Health Association Resource (SHARe).


dbdate: 11/24/2011
author: Won HH
date: 10/21/2011
journal: Cancer
link: http://www.ncbi.nlm.nih.gov/pubmed/22020760
trait: Response to platinum-based agents
initial_samplesize: 96 colon cancer cases
replication_samplesize: 247 colon cancer cases
study:
Polymorphic markers associated with severe oxaliplatin-induced, chronic peripheral neuropathy in colon cancer patients.


dbdate: 11/30/2011
author: Surakka I
date: 10/20/2011
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22028671
trait: Lipid traits
initial_samplesize: Up to 32,225 European ancestry individuals
replication_samplesize: 22,702 European ancestry individuals
study:
A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol.


dbdate: 11/30/2011
author: Hinney A
date: 10/19/2011
journal: Am J Med Genet B Neuropsychiatr Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22012869
study: Genome-wide association study in German patients with attention deficit/hyperactivity disorder.
trait: Attention deficit hyperactivity disorder
initial_samplesize: 495 European ancestry child and adolescent cases, 1,300 European ancestry adult controls
replication_samplesize:
1023 individuals (from 320 families with at least one affected child), 896 controls and 2455 cases (from 2064 trios)


dbdate: 11/18/2011
author: Frank J
date: 10/18/2011
journal: Addict Biol
link: http://www.ncbi.nlm.nih.gov/pubmed/22004471
trait: Alcohol dependence
initial_samplesize: 1,333 European ancestry cases, 2,168 European ancestry controls
study:
Genome-wide significant association between alcohol dependence and a variant in the ADH gene cluster.


dbdate: 11/19/2011
author: Hollingworth P
date: 10/18/2011
journal: Mol Psychiatry
link: http://www.ncbi.nlm.nih.gov/pubmed/22005930
study: Genome-wide association study of Alzheimer's disease with psychotic symptoms.
trait: Alzheimer's disease
initial_samplesize:
1,299 European ancestry, African American ancestry and Native American ancestry cases with psychosis, 735 European ancestry, African American ancestry and Native American ancestry cases without psychosis, 5,659 European ancestry, African American ancestry and Native American ancestry controls


dbdate: 11/09/2011
author: Wu X
date: 10/18/2011
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22010048
trait: Renal cell carcinoma
initial_samplesize: 894 European ancestry cases, 1,516 European ancestry controls
replication_samplesize: 3,772 European ancestry cases, 8,505 European ancestry controls
study:
A genome-wide association study identifies a novel susceptibility locus for renal cell carcinoma on 12p11.23.


dbdate: 11/15/2011
author: Yoon D
date: 10/18/2011
journal: Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22006218
trait: Smoking behavior
initial_samplesize: 8,842 Korean ancestry individuals
replication_samplesize: 1,366 African American ancestry individuals, 671 European ancestry individuals
study:
Large-scale genome-wide association study of Asian population reveals genetic factors in FRMD4A and other loci influencing smoking initiation and nicotine dependence.


dbdate: 11/18/2011
author: Chambers JC
date: 10/16/2011
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22001757
trait: Liver enzyme levels (alanine transaminase)
initial_samplesize: Up to 52,350 European ancestry individuals, up to 8,739 Indian Asian individuals
study:
Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.


dbdate: 11/09/2011
author: Khor CC
date: 10/16/2011
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/22001756
trait: Dengue shock syndrome
initial_samplesize: 2,008 Vietnamese ancestry cases, 2,018 Vietnamese ancestry controls
replication_samplesize: 1,737 Vietnamese ancestry cases, 2,934 Vietnamese ancestry controls
study:
Genome-wide association study identifies susceptibility loci for dengue shock syndrome at MICB and PLCE1.


dbdate: 11/16/2011
author: Grallert H
date: 10/14/2011
journal: Eur Heart J
link: http://www.ncbi.nlm.nih.gov/pubmed/22003152
trait: Lipoprotein-associated phospholipase A2 activity and mass
initial_samplesize: 12,126 European ancestry individuals, 1,538 Other ancestry individuals
study:
Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies.


dbdate: 11/18/2011
author: Kuparinen T
date: 10/13/2011
journal: Genes Immun
link: http://www.ncbi.nlm.nih.gov/pubmed/21993531
trait: Cytomegalovirus antibody response
initial_samplesize: 1,485 European ancestry sero-postitive individuals, 648 European ancestry sero-negative individuals
study:
Genome-wide association study does not reveal major genetic determinants for anti-cytomegalovirus antibody response.


dbdate: 11/04/2011
author: Drago A
date: 10/11/2011
journal: Am J Med Genet B Neuropsychiatr Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21990027
trait: Response to antipsychotic therapy (extrapyramidal side effects)
initial_samplesize: 409 European or other ancestry bipolar cases
study:
The genetics of antipsychotic induced tremors: a genome-wide pathway analysis on the STEP-BD SCP sample.


dbdate: 12/10/2011
author: Denny JC
date: 10/07/2011
journal: Am J Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21981779
trait: Hypothyroidism
initial_samplesize: 1,317 European ancestry cases, 5,053 European ancestry controls
replication_samplesize: 263 European ancestry cases, 1,616 European ancestry controls
study:
Variants near FOXE1 are associated with hypothyroidism and other thyroid conditions: using electronic medical records for genome- and phenome-wide studies.


dbdate: 11/04/2011
author: Li X
date: 10/06/2011
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21979947
trait: Corneal structure
initial_samplesize: 222 European ancestry cases, 3,324 European ancestry controls
study:
A genome-wide association study identifies a potential novel gene locus for keratoconus, one of the commonest causes for corneal transplantation in developed countries.

replication_samplesize:
304 European ancestry cases, 518 European ancestry controls, 146 European ancestry cases and 161 European ancestry controls from 70 families


dbdate: 11/08/2011
author: N'Diaye A
date: 10/06/2011
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21998595
trait: Height
initial_samplesize: 20,427 African ancestry individuals
replication_samplesize: Up to 16,436 African American individuals
study:
Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry.


dbdate: 11/04/2011
author: Liu L
date: 10/01/2011
journal: Viral Immunol
link: http://www.ncbi.nlm.nih.gov/pubmed/22004137
trait: Hepatitis B
initial_samplesize: 1,944 Han Chinese ancestry progressed cases, 854 Han Chinese ancestry asymptomatic carriers
study:
A genome-wide association study with DNA pooling identifies the variant rs11866328 in the GRIN2A gene that affects disease progression of chronic HBV infection.


dbdate: 10/22/2011
author: Zuo L
date: 09/28/2011
journal: Neuropsychopharmacology
link: http://www.ncbi.nlm.nih.gov/pubmed/21956439
study: Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q.
trait: Alcohol dependence
initial_samplesize:
1,409 European ancestry cases, 1,518 European ancestry controls, 681 African American cases, 508 African American controls


dbdate: 10/20/2011
author: Middelberg RP
date: 09/24/2011
journal: BMC Med Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21943158
trait: Cardiovascular disease risk factors
initial_samplesize: 11,683 European ancestry individuals
study:
Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.


dbdate: 10/07/2011
author: Amos CI
date: 09/22/2011
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21926416
study: Genome-wide association study identifies novel loci predisposing to cutaneous melanoma.
trait: Melanoma
initial_samplesize: 1,804 European ancestry cases, 1,026 European ancestry controls
replication_samplesize:
6,483 European and Middle East/North African ancestry cases, 23,324 European and Middle East/North African ancestry controls


dbdate: 10/19/2011
author: Sklar P
date: 09/18/2011
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21926972
trait: Bipolar disorder
initial_samplesize: 7,481 European ancestry cases, 9,250 European ancestry controls
replication_samplesize: 4,496 European ancestry cases, 42,422 European ancestry controls
study:
Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4.


dbdate: 10/06/2011
author: Paternoster L
date: 09/15/2011
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/21935397
trait: Obesity (extreme)
initial_samplesize: 2,633 European ancestry extremely obese adults, 2,740 European ancestry controls
replication_samplesize: 29,181 European ancestry individuals
study:
Genome-wide population-based association study of extremely overweight young adults--the GOYA study.


dbdate: 10/07/2011
author: Tohkin M
date: 09/13/2011
journal: Pharmacogenomics J
link: http://www.ncbi.nlm.nih.gov/pubmed/21912425
trait: Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS-TEN)
initial_samplesize: 14 Japanese ancestry cases, 991 Japanese ancestry controls
study:
A whole-genome association study of major determinants for allopurinol-related Stevens-Johnson syndrome and toxic epidermal necrolysis in Japanese patients.


dbdate: 10/05/2011
author: Arakawa S
date: 09/11/2011
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21909106
trait: Age-related macular degeneration
initial_samplesize: 827 Japanese ancestry cases, 3,323 Japanese ancestry controls
replication_samplesize: 709 Japanese ancestry cases, 15,571 Japanese ancestry controls
study:
Genome-wide association study identifies two susceptibility loci for exudative age-related macular degeneration in the Japanese population.


dbdate: 10/07/2011
author: Bis JC
date: 09/11/2011
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21909108
trait: Carotid intima media thickness
initial_samplesize: Up to 31,211 European ancestry individuals
replication_samplesize: 11,273 European ancestry individuals
study:
Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque.


dbdate: 10/11/2011
author: Kim YJ
date: 09/11/2011
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21909109
trait: Gamma glutamyl transpeptidase
initial_samplesize: 12,545 Korean ancestry individuals
replication_samplesize: Up to 30,395 East Asian ancestry individuals
study:
Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.


dbdate: 10/06/2011
author: Lemaire SA
date: 09/11/2011
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21909107
trait: Thoracic aortic aneurysms and dissections
initial_samplesize: 765 European ancestry cases, 874 European ancestry controls
replication_samplesize: 548 European ancestry cases, 626 European ancestry controls
study:
Genome-wide association study identifies a susceptibility locus for thoracic aortic aneurysms and aortic dissections spanning FBN1 at 15q21.1.


dbdate: 10/11/2011
author: Wain LV
date: 09/11/2011
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21909110
trait: Blood pressure
initial_samplesize: 74,064 European ancestry individuals
replication_samplesize: 48,607 European ancestry individuals
study:
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure.


dbdate: 10/01/2011
author: Chen D
date: 09/10/2011
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21896673
study: Genome-wide association study of HPV seropositivity.
trait: HPV seropositivity
replication_samplesize: 1,307 Hispanic head and neck cancer cases, 1,037 Hispanic controls
initial_samplesize:
1,286 European ancestry lung cancer cases, 679 European ancestry head and neck cancer cases, 811 European ancestry kidney cancer cases, 2,035 European ancestry controls


dbdate: 09/30/2011
author: Cai Q
date: 09/09/2011
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21908515
trait: Breast cancer
initial_samplesize: 2,062 East Asian ancestry cases, 2,066 East Asian ancestry controls
replication_samplesize: 15,091 East Asian ancestry cases, 14,877 East Asian ancestry controls
study:
Genome-wide association study identifies breast cancer risk variant at 10q21.2: results from the Asia Breast Cancer Consortium.


dbdate: 09/30/2011
author: Nakabayashi K
date: 09/08/2011
journal: J Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21900946
trait: Graves' disease
initial_samplesize: 1,119 Japanese ancestry cases, 2,718 Japanese ancestry controls
replication_samplesize: 432 Japanese ancestry cases, 1,157 Japanese ancestry controls
study:
Identification of independent risk loci for Graves' disease within the MHC in the Japanese population.


dbdate: 02/10/2012
author: Nicholson G
date: 09/08/2011
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21931564
trait: Metabolite levels
initial_samplesize: 142 European ancestry female twins
replication_samplesize: 202 European ancestry individuals
study:
A genome-wide metabolic QTL analysis in Europeans implicates two loci shaped by recent positive selection.


dbdate: 09/30/2011
author: Qi Q
date: 09/06/2011
journal: Eur Heart J
link: http://www.ncbi.nlm.nih.gov/pubmed/21900290
trait: Lp (a) levels
initial_samplesize: 1,450 European ancestry individuals
study:
Genetic variants, plasma lipoprotein(a) levels, and risk of cardiovascular morbidity and mortality among two prospective cohorts of type 2 diabetes.


dbdate: 09/30/2011
author: Amin N
date: 08/30/2011
journal: Mol Psychiatry
link: http://www.ncbi.nlm.nih.gov/pubmed/21876539
trait: Coffee consumption
initial_samplesize: 18,176 European ancestry individuals
replication_samplesize: 7,929 European ancestry individuals
study:
Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM.


dbdate: 09/28/2011
author: Sampietro ML
date: 08/30/2011
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21878436
trait: Coronary restenosis
initial_samplesize: 295 European ancestry cases, 571 European ancestry controls
replication_samplesize: 455 European ancestry cases, 2,880 European ancestry controls
study:
A genome-wide association study identifies a region at chromosome 12 as a potential susceptibility locus for restenosis after percutaneous coronary intervention.


dbdate: 09/28/2011
author: Kooner JS
date: 08/28/2011
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21874001
trait: Type 2 diabetes
initial_samplesize: 5,561 South Asian ancestry cases, 14,458 South Asian ancestry controls
replication_samplesize: 13,170 South Asian ancestry cases, 25,398 South Asian ancestry controls
study:
Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci.


dbdate: 09/27/2011
author: Lydall GJ
date: 08/26/2011
journal: Psychiatr Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21876473
trait: Alcohol dependence
initial_samplesize: 506 European ancestry cases, 510 European ancestry controls
study:
Confirmation of prior evidence of genetic susceptibility to alcoholism in a genome-wide association study of comorbid alcoholism and bipolar disorder.


dbdate: 09/27/2011
author: Strawbridge RJ
date: 08/26/2011
journal: Diabetes
link: http://www.ncbi.nlm.nih.gov/pubmed/21873549
trait: Proinsulin levels
initial_samplesize: 10,701 European ancestry individuals
replication_samplesize: 16,378 European ancestry individuals
study:
Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes.


dbdate: 09/27/2011
author: Ahn MJ
date: 08/25/2011
journal: Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21866343
trait: Non-small cell lung cancer
initial_samplesize: 445 Korean ancestry cases, 497 Korean ancestry controls
replication_samplesize: 396 Korean ancestry cases, 998 Korean ancestry controls
study:
The 18p11.22 locus is associated with never smoker non-small cell lung cancer susceptibility in Korean populations.


dbdate: 09/27/2011
author: Irvin MR
date: 08/25/2011
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/21901158
trait: Insulin resistance/response
initial_samplesize: 1,040 African American individuals
study:
Genome-wide detection of allele specific copy number variation associated with insulin resistance in African Americans from the HyperGEN study.


dbdate: 09/22/2011
author: Benyamin B
date: 08/23/2011
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21862451
trait: Butyrylcholinesterase levels
initial_samplesize: 6,879 European ancestry adults
replication_samplesize: 1,260 European ancestry adults, 652 European ancestry adolescents
study:
GWAS of butyrylcholinesterase activity identifies four novel loci, independent effects within BCHE and secondary associations with metabolic risk factors.


dbdate: 09/23/2011
author: Larsson M
date: 08/12/2011
journal: Am J Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21835309
trait: Iris characteristics
initial_samplesize: 2,121 European ancestry individuals
replication_samplesize: 499 European ancestry adolescent twins and siblings, 73 European ancestry adults
study:
GWAS findings for human iris patterns: associations with variants in genes that influence normal neuronal pattern development.


dbdate: 09/21/2011
author: Yang TH
date: 08/09/2011
journal: BMC Med Genomics
link: http://www.ncbi.nlm.nih.gov/pubmed/21827660
trait: Glioma
initial_samplesize: 781 European ancestry cases, 3,992 European ancestry controls
study:
Combinations of newly confirmed Glioma-Associated loci link regions on chromosomes 1 and 9 to increased disease risk.


dbdate: 09/17/2011
author: Garcia-Closas M
date: 08/08/2011
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21824976
trait: Bladder cancer
initial_samplesize: 4,501 European ancestry cases, 6,076 European ancestry controls
replication_samplesize: 1,382 European ancestry cases, 2,201 European ancestry controls
study:
A genome-wide association study of bladder cancer identifies a new susceptibility locus within SLC14A1, a urea transporter gene on chromosome 18q12.3.


dbdate: 09/14/2011
author: Liu X
date: 08/03/2011
journal: BMC Med Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21812969
trait: Parkinson's disease
initial_samplesize: 268 Ashkenazi Jewish cases, 178 Ashkenazi Jewish controls
replication_samplesize: 1,782 European ancestry cases, 1,658 European ancestry controls
study:
Genome-wide association study identifies candidate genes for Parkinson's disease in an Ashkenazi Jewish population.


dbdate: 09/06/2011
author: Chantarangsu S
date: 08/01/2011
journal: Clin Infect Dis
link: http://www.ncbi.nlm.nih.gov/pubmed/21810746
trait: Nevirapine-induced rash
replication_samplesize: 88 Thai ancestry nevirapine-induced rash HIV cases, 145 Thai ancestry nevirapine-tolerant HIV cases
study:
Genome-wide association study identifies variations in 6p21.3 associated with nevirapine-induced rash.

initial_samplesize:
72 Thai ancestry nevirapine-induced rash HIV cases, 77 Thai ancestry nevirapine-tolerant rash HIV cases


dbdate: 09/06/2011
author: Mehta NN
date: 08/01/2011
journal: Circ Cardiovasc Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21846871
trait: Coronary heart disease
initial_samplesize: 8,424 European ancestry cases, 6,996 South Asian cases, 15,062 controls
replication_samplesize: 21,408 cases, 19,185 controls
study:
A genome-wide association study in europeans and South asians identifies 5 new Loci for coronary artery disease.


dbdate: 08/27/2011
author: Hirota T
date: 07/31/2011
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21804548
trait: Asthma
initial_samplesize: 1,532 Japanese ancestry cases, 3,304 Japanese ancestry controls
replication_samplesize: 5,639 Japanese ancestry cases, 24,608 Japanese ancestry controls
study:
Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population.


dbdate: 08/20/2011
author: Torgerson DG
date: 07/31/2011
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21804549
trait: Asthma
study:
Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.

initial_samplesize:
2,088 European ancestry cases, 1,612 African American and African Caribbean cases, 1,688 Hispanic cases

replication_samplesize:
2,727 European ancestry cases, 2,147 African American and African Caribbean cases, 2,299 Hispanic cases


dbdate: 09/01/2011
author: Lemaitre RN
date: 07/28/2011
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21829377
trait: Phospholipid levels (plasma)
initial_samplesize: 8,866 European ancestry individuals
study:
Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.


dbdate: 08/18/2011
author: Traglia M
date: 07/25/2011
journal: J Med Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21785125
trait: Hepcidin levels
initial_samplesize: 1,657 Val Borbera individuals
study:
Association of HFE and TMPRSS6 genetic variants with iron and erythrocyte parameters is only in part dependent on serum hepcidin concentrations.


dbdate: 08/18/2011
author: Cui B
date: 07/22/2011
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/21799836
trait: Type 2 diabetes
initial_samplesize: 793 Han Chinese ancestry cases, 806 Han Chinese ancestry controls
replication_samplesize: 4,445 Han Chinese ancestry cases, 4,458 Han Chinese ancestry controls
study:
A genome-wide association study confirms previously reported loci for type 2 diabetes in Han Chinese.


dbdate: 09/02/2011
author: Noguchi E
date: 07/21/2011
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21814517
trait: Asthma
initial_samplesize: 938 Japanese ancestry cases, 2,376 Japanese ancestry controls
replication_samplesize: 1653 East Asian ancestry cases, 1453 East Asian ancestry controls
study:
Genome-wide association study identifies HLA-DP as a susceptibility gene for pediatric asthma in Asian populations.


dbdate: 08/18/2011
author: Chung CM
date: 07/19/2011
journal: Diabetes
link: http://www.ncbi.nlm.nih.gov/pubmed/21771975
trait: Adiponectin levels
initial_samplesize: 382 Han Chinese ancestry young-onset-hypertensive cases
replication_samplesize: 559 Han Chinese ancestry young-onset-hypertensive cases
study:
A genome-wide association study reveals a quantitative trait locus of adiponectin on CDH13 that predicts cardiometabolic outcomes.


dbdate: 08/12/2011
author: Tin A
date: 07/18/2011
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21768215
trait: Urate levels
initial_samplesize: 8,651 African American individuals
replication_samplesize: 1,996 African American individuals
study:
Genome-wide association study for serum urate concentrations and gout among African Americans identifies genomic risk loci and a novel URAT1 loss-of-function allele.


dbdate: 08/06/2011
author: Png E
date: 07/15/2011
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21764829
trait: Hepatitis B vaccine response
initial_samplesize: 1,683 Indonesian ancestry individuals
replication_samplesize: 1,931 Indonesian ancestry individuals
study:
A genome-wide association study of hepatitis B vaccine response in an Indonesian population reveals multiple independent risk variants in the HLA region.


dbdate: 08/12/2011
author: Debette S
date: 07/14/2011
journal: Circ Res
link: http://www.ncbi.nlm.nih.gov/pubmed/21757650
trait: Vascular endothelial growth factor levels
initial_samplesize: 3,527 European ancestry individuals
replication_samplesize: 1,727 European ancestry individuals
study:
Identification of cis- and trans-acting genetic variants explaining up to half the variation in circulating vascular endothelial growth factor levels.


dbdate: 08/12/2011
author: Gorlova O
date: 07/14/2011
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21779181
trait: Systemic sclerosis
initial_samplesize: 2,296 European ancestry cases, 5,172 European ancestry controls
replication_samplesize: 3,175 European ancestry cases, 4,210 European ancestry controls
study:
Identification of novel genetic markers associated with clinical phenotypes of systemic sclerosis through a genome-wide association strategy.


dbdate: 08/12/2011
author: Lovely RS
date: 07/14/2011
journal: Arterioscler Thromb Vasc Biol
link: http://www.ncbi.nlm.nih.gov/pubmed/21757653
trait: Fibrinogen
initial_samplesize: 3,042 individuals
study:
Assessment of genetic determinants of the association of &#x003b3;' fibrinogen in relation to cardiovascular disease.


dbdate: 08/15/2011
author: Schurks M
date: 07/14/2011
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/21779381
trait: Cardiovascular disease risk factors
initial_samplesize: 5,122 European ancestry female migrain cases
study:
Genetic determinants of cardiovascular events among women with migraine: a genome-wide association study.


dbdate: 08/15/2011
author: Winkelmann J
date: 07/14/2011
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21779176
trait: Restless legs syndrome
initial_samplesize: 922 European ancestry cases, 1,526 European ancestry controls
replication_samplesize: 3,935 European ancestry cases, 5,754 European ancestry controls
study:
Genome-wide association study identifies novel restless legs syndrome susceptibility loci on 2p14 and 16q12.1.


dbdate: 08/05/2011
author: Mbarek H
date: 07/12/2011
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21750111
trait: Hepatitis B
initial_samplesize: 458 Japanese ancestry cases, 2,056 Japanese ancestry controls
replication_samplesize: 2,209 Japanese ancestry cases, 4,440 Japanese ancestry controls
study:
A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population.


dbdate: 08/05/2011
author: Rafnar T
date: 07/12/2011
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21750109
trait: Bladder cancer
initial_samplesize: 2,234 European ancestry cases, 41,603 European ancestry controls
study:
European genome-wide association study identifies SLC14A1 as a new urinary bladder cancer susceptibility gene.

replication_samplesize:
3,371 European ancestry cases, 10,261 European ancestry controls, 269 Iranian ancestry cases, 246 Iranian ancestry controls


dbdate: 07/30/2011
author: Evans DM
date: 07/10/2011
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21743469
trait: Ankylosing spondylitis
initial_samplesize: 3,023 European ancestry cases, 8,779 European ancestry controls
replication_samplesize: 2,111 European ancestry cases, 4,483 European ancestry controls
study:
Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility.


dbdate: 08/22/2011
author: Kote-Jarai Z
date: 07/10/2011
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21743467
trait: Prostate cancer
initial_samplesize: 6,621 European ancestry cases, 6,939 European ancestry controls
study:
Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study.

replication_samplesize:
22,957 European ancestry cases, 23,234 European ancestry controls, 420 East Asian ancestry cases, 433 East Asian ancestry controls, 112 African American cases, 298 African American controls, 7,140 Other ancestry cases, 5,455 Other ancestry controls


dbdate: 08/03/2011
author: Major JM
date: 07/05/2011
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21729881
trait: Vitamin E levels
initial_samplesize: 2,402 European ancestry cases, 1612 European ancestry controls
study:
Genome-wide association study identifies common variants associated with circulating vitamin E levels.

replication_samplesize:
475 European ancestry cases, 517 European ancestry controls, 1,416 Other ancestry cases, 1,359 Other ancestry controls


dbdate: 08/03/2011
author: Hu Z
date: 07/03/2011
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21725308
trait: Lung cancer
initial_samplesize: 2,331 Han Chinese ancestry cases, 3,077 Han Chinese ancestry controls
replication_samplesize: 6,313 Han Chinese ancestry cases, 6,409 Han Chinese ancestry controls
study:
A genome-wide association study identifies two new lung cancer susceptibility loci at 13q12.12 and 22q12.2 in Han Chinese.


dbdate: 07/29/2011
author: Miki D
date: 07/03/2011
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21725309
trait: Chronic hepatitis C infection
study:
Variation in the DEPDC5 locus is associated with progression to hepatocellular carcinoma in chronic hepatitis C virus carriers.

initial_samplesize:
212 Japanese ancestry chronic hepatitis C with hepatocellular carcinoma cases, 765 Japanese ancestry chronic hepatitis C without hepatocellular carcinoma cases

replication_samplesize:
710 Japanses ancestry chronic hepatitis C with hepatocellular carcinoma cases, 1,625 Japanese ancestry chronic hepatitis C without hepatocellular carcinoma cases


dbdate: 08/06/2011
author: Nyberg F
date: 07/01/2011
journal: Pharmacogenomics
link: http://www.ncbi.nlm.nih.gov/pubmed/21787189
trait: Interstitial lung disease
initial_samplesize: 80 Japanese ancestry cases, 194 Japanese ancestry controls
study:
Interstitial lung disease in gefitinib-treated Japanese patients with non-small-cell lung cancer: genome-wide analysis of genetic data.


dbdate: 07/19/2011
author: Arking DE
date: 06/30/2011
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21738491
trait: Sudden cardiac arrest
initial_samplesize: 1,283 European ancestry cases, ~20,000 European ancestry controls
replication_samplesize: 3,119 European ancestry cases, 11,146 European ancestry controls
study:
Identification of a sudden cardiac death susceptibility locus at 2q24.2 through genome-wide association in European ancestry individuals.


dbdate: 07/21/2011
author: Okada Y
date: 06/30/2011
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21738478
trait: White blood cell types
initial_samplesize: 8,794 Japanese ancestry individuals
replication_samplesize: 5,998 Japanese ancestry individuals
study:
Identification of nine novel loci associated with white blood cell subtypes in a Japanese population.


dbdate: 07/27/2011
author: Reiner AP
date: 06/30/2011
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21738479
trait: White blood cell count
initial_samplesize: 16,388 African American individuals
study:
Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT).

replication_samplesize:
3,551 Hispanic individuals, 14,767 Japanese ancestry individuals, 19,509 European ancestry individuals


dbdate: 07/27/2011
author: Smith EN
date: 06/30/2011
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21738484
trait: Bipolar disorder
initial_samplesize: 1,190 European and unknown ancestry cases, 401 European and unknown ancestry controls
replication_samplesize: 16,179 individuals
study:
Genome-wide association of bipolar disorder suggests an enrichment of replicable associations in regions near genes.


dbdate: 07/20/2011
author: Nebel A
date: 06/29/2011
journal: Mech Ageing Dev
link: http://www.ncbi.nlm.nih.gov/pubmed/21740922
trait: Longevity
initial_samplesize: 763 European ancestry individuals, 1,058 European ancestry individuals
replication_samplesize: 754 European ancestry individuals, 860 European ancestry individuals
study:
A genome-wide association study confirms APOE as the major gene influencing survival in long-lived individuals.


dbdate: 07/20/2011
author: Teerlink C
date: 06/26/2011
journal: Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21706340
trait: Melanoma
initial_samplesize: 156 European ancestry cases from 34 high-risk families, 2,150 European ancestry controls
study:
A unique genome-wide association analysis in extended Utah high-risk pedigrees identifies a novel melanoma risk variant on chromosome arm 10q.


dbdate: 07/20/2011
author: Do CB
date: 06/23/2011
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21738487
trait: Parkinson's disease
initial_samplesize: 3,426 European ancestry cases, 29,624 European ancestry controls
study:
Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.


dbdate: 07/13/2011
author: Nan H
date: 06/23/2011
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21700618
trait: Basal cell carcinoma
initial_samplesize: 2,045 European ancestry cases, 6,013 European ancestry controls
replication_samplesize: 1,426 cases, 4,845 controls
study:
Genome-wide association study identifies novel alleles associated with risk of cutaneous basal cell carcinoma and squamous cell carcinoma.


dbdate: 07/14/2011
author: Wang KS
date: 06/22/2011
journal: J Psychiatr Res
link: http://www.ncbi.nlm.nih.gov/pubmed/21703634
trait: Alcohol dependence
initial_samplesize: 1,283 European ancestry cases, 1,416 European ancestry controls
replication_samplesize: 1,650 European ancestry cases and 1,684 European ancestry controls from 778 nuclear families
study:
A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence.


dbdate: 07/12/2011
author: Okada Y
date: 06/20/2011
journal: Gastroenterology
link: http://www.ncbi.nlm.nih.gov/pubmed/21699788
trait: Inflammatory bowel disease
initial_samplesize: 372 Japanese ancestry Crohn's disease cases, 372 Japanese ancestry ulcerative colitis cases
study:
HLA-Cw*1202-B*5201-DRB1*1502 haplotype increases risk for ulcerative colitis but reduces risk for Crohn's disease.

replication_samplesize:
607 Japanese ancestry Crohn's disease cases, 376 Japanese ancestry ulcerative colitis cases, 905 Japanese ancestry controls


dbdate: 07/14/2011
author: Hoglinger GU
date: 06/19/2011
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21685912
study: Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy.
trait: Progressive supranuclear palsy
replication_samplesize: 1,051 European ancestry cases, 3,560 European ancestry controls
initial_samplesize:
1,069 European ancestry cases, 2,958 European ancestry controls, 45 cases, 329 Other ancestry controls


dbdate: 06/29/2011
author: Eleftherohorinou H
date: 06/13/2011
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21653640
trait: Rheumatoid arthritis
study:
Pathway-driven gene stability selection of two rheumatoid arthritis GWAS identifies and validates new susceptibility genes in receptor mediated signalling pathways.

initial_samplesize:
1,860 European ancestry cases, 2,938 European ancestry controls, 908 Other ancestry cases, 1,260 Other ancestry controls


dbdate: 06/29/2011
author: Sun LD
date: 06/13/2011
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21666691
trait: Atopic dermatitis
initial_samplesize: 1,012 Han Chinese ancestry cases, 1,362 Han Chinese ancestry controls
study:
Genome-wide association study identifies two new susceptibility loci for atopic dermatitis in the Chinese Han population.

replication_samplesize:
3,624 Han Chinese ancestry cases, 12,197 Han Chinese ancestry controls, 1,806 European ancestry cases, 3,256 European ancestry controls


dbdate: 06/23/2011
author: Chasman DI
date: 06/12/2011
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21666692
trait: Migraine
initial_samplesize: 5,122 European ancestry cases, 18,108 European ancestry controls
replication_samplesize: 3,831 European ancestry cases, 13,889 European ancestry controls
study:
Genome-wide association study reveals three susceptibility loci for common migraine in the general population.


dbdate: 07/20/2011
author: Aouizerat BE
date: 06/10/2011
journal: BMC Cardiovasc Disord
link: http://www.ncbi.nlm.nih.gov/pubmed/21658281
trait: Sudden cardiac arrest
initial_samplesize: 88 European ancestry cases, 517 European ancestry controls
study:
GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.


dbdate: 06/29/2011
author: Han S
date: 06/10/2011
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21665993
trait: Corneal curvature
initial_samplesize: 2,008 Chinese ancestry inidividuals, 2,281 Malay ancestry individuals
replication_samplesize: 2,142 Asian Indian ancestry individuals, 929 Chinese ancestry children
study:
Association of variants in FRAP1 and PDGFRA with corneal curvature in Asian populations from Singapore.


dbdate: 06/29/2011
author: Yu Y
date: 06/10/2011
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21665990
trait: Age-related macular degeneration
initial_samplesize: 2,594 European ancestry cases, 4,134 European ancestry controls
replication_samplesize: 5,640 European ancestry cases, 52,174 European ancestry controls
study:
Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration.


dbdate: 06/25/2011
author: Tanaka Y
date: 06/09/2011
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21659334
trait: Response to hepatitis C treatment
initial_samplesize: 303 Japanese ancestry cases
replication_samplesize: 391 Japanese ancestry cases
study:
Genome-wide association study identified ITPA/DDRGK1 variants reflecting thrombocytopenia in pegylated interferon and ribavirin therapy for chronic hepatitis C.


dbdate: 06/25/2011
author: Wade R
date: 06/09/2011
journal: Haematologica
link: http://www.ncbi.nlm.nih.gov/pubmed/21659360
trait: Response to antineoplastic agents
initial_samplesize: 356 European ancestary cases
replication_samplesize: 380 European ancestry cases
study:
Association between single nucleotide polymorphism-genotype and outcome of patients with chronic lymphocytic leukemia in a randomized chemotherapy trial.


dbdate: 06/18/2011
author: Below JE
date: 06/07/2011
journal: Diabetologia
link: http://www.ncbi.nlm.nih.gov/pubmed/21647700
trait: Type 2 diabetes
initial_samplesize: 837 Mexican-American cases, 436 Mexican-American controls
replication_samplesize: 967 Mexican ancestry cases, 343 Mexican ancestry controls
study:
Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals.


dbdate: 06/18/2011
author: Wu Y
date: 06/07/2011
journal: Inflammation
link: http://www.ncbi.nlm.nih.gov/pubmed/21647738
trait: C-reactive protein
initial_samplesize: 1,709 Filipino ancestry females
study:
Genome-wide association with C-reactive protein levels in CLHNS: evidence for the CRP and HNF1A loci and their interaction with exposure to a pathogenic environment.


dbdate: 06/20/2011
author: Bielinski SJ
date: 06/06/2011
journal: Mayo Clin Proc
link: http://www.ncbi.nlm.nih.gov/pubmed/21646302
trait: Bilirubin levels
initial_samplesize: 6,307 European ancestry individuals
study:
Mayo Genome Consortia: a genotype-phenotype resource for genome-wide association studies with an application to the analysis of circulating bilirubin levels.


dbdate: 06/16/2011
author: Wu C
date: 06/05/2011
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21642993
trait: Esophageal cancer
initial_samplesize: 2,031 Han Chinese ancestry cases, 2,044 Han Chinese ancestry controls
replication_samplesize: 3,986 Han Chinese ancestry cases, 4,157 Han Chinese ancestry controls
study:
Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations.


dbdate: 06/23/2011
author: Antunez C
date: 05/31/2011
journal: Genome Med
link: http://www.ncbi.nlm.nih.gov/pubmed/21627779
trait: Alzheimer's disease
initial_samplesize: 319 European ancestry cases, 769 European ancestry controls, 2,690 cases, 2,237 controls
study:
The membrane-spanning 4-domains, subfamily A (MS4A) gene cluster contains a common variant associated with Alzheimer's disease.

replication_samplesize:
4,982 European ancestry cases, 7,961 European ancestry controls, 2,190 Other ancestry cases, 3,374 Other ancestry controls


dbdate: 06/14/2011
author: Aragam N
date: 05/26/2011
journal: J Affect Disord
link: http://www.ncbi.nlm.nih.gov/pubmed/21621269
trait: Major depressive disorder
initial_samplesize: 1,726 Other ancestry cases, 1,630 Other ancestry controls
study:
Genome-wide association analysis of gender differences in major depressive disorder in the Netherlands NESDA and NTR population-based samples.


dbdate: 06/14/2011
author: Malovini A
date: 05/25/2011
journal: Rejuvenation Res
link: http://www.ncbi.nlm.nih.gov/pubmed/21612516
trait: Longevity
initial_samplesize: 410 European ancestry long-living individuals, 553 European ancestry young individuals
replication_samplesize: 116 European ancestry long-living individuals, 160 European ancestry young individuals
study:
Association study on long-living individuals from Southern Italy identifies rs10491334 in the CAMKIV gene that regulates survival proteins.


dbdate: 06/04/2011
author: Wild PS
date: 05/23/2011
journal: Circ Cardiovasc Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21606135
trait: Coronary heart disease
initial_samplesize: 2,078 European ancestry cases, 2,953 European ancestry controls
replication_samplesize: 19,350 European ancestry cases, 35,408 European ancestry controls
study:
A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease.


dbdate: 06/03/2011
author: Haiman CA
date: 05/22/2011
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21602798
trait: Prostate cancer
initial_samplesize: 3,425 African American cases, 3,290 African American controls
study:
Genome-wide association study of prostate cancer in men of African ancestry identifies a susceptibility locus at 17q21.

replication_samplesize:
1,500 African American/Afro-Caribbean cases, 1,908 African American/Afro-Caribbean controls, 344 Sub-Saharan African ancestry cases, 1,361 Sub-Saharan African ancestry controls


dbdate: 06/07/2011
author: Wright FA
date: 05/22/2011
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21602797
trait: Cystic fibrosis severity
initial_samplesize: 2,317 European ancestry cases, 177 cases
replication_samplesize: 898 European ancestry sibling pair cases, 75 sibling pair cases
study:
Genome-wide association and linkage identify modifier loci of lung disease severity in cystic fibrosis at 11p13 and 20q13.2.


dbdate: 07/30/2011
author: Thompson AJ
date: 05/20/2011
journal: J Hepatol
link: http://www.ncbi.nlm.nih.gov/pubmed/21703177
study: Genome-wide association study of interferon-related cytopenia in chronic hepatitis C patients.
trait: IFN-related cytopenia
initial_samplesize:
984 European ancestry with genotype 1 HCV cases, 201 African American genotype 1 HCV cases, 99 Hispanic genotype 1 HCV cases


dbdate: 07/13/2011
author: Kato N
date: 05/15/2011
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21572416
trait: Blood pressure
initial_samplesize: 19,608 East Asian ancestry individuals
replication_samplesize: 30,765 East Asian ancestry individuals
study:
Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians.


dbdate: 06/03/2011
author: Parra EJ
date: 05/15/2011
journal: Diabetologia
link: http://www.ncbi.nlm.nih.gov/pubmed/21573907
trait: Type 2 diabetes
initial_samplesize: 1,804 Hispanic cases, 780 Hispanic controls
replication_samplesize: (NR) European ancestry individuals
study:
Genome-wide association study of type 2 diabetes in a sample from Mexico City and a meta-analysis of a Mexican-American sample from Starr County, Texas.


dbdate: 06/01/2011
author: Teumer A
date: 05/13/2011
journal: Am J Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21565293
trait: Thyroid volume
initial_samplesize: 3,620 European ancestry individuals
replication_samplesize: 1,290 European ancestry individuals
study:
Genome-wide association study identifies four genetic loci associated with thyroid volume and goiter risk.


dbdate: 05/27/2011
author: Kanetsky PA
date: 05/06/2011
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21551455
trait: Testicular cancer
initial_samplesize: 349 European ancestry cases, 919 European ancestry controls
replication_samplesize: 439 European ancestry cases,960 European ancestry controls
study:
A second independent locus within DMRT1 is associated with testicular germ cell tumor susceptibility.


dbdate: 06/01/2011
author: Guerrero JA
date: 05/03/2011
journal: Haematologica
link: http://www.ncbi.nlm.nih.gov/pubmed/21546496
trait: Platelet function and related traits
initial_samplesize: 70 children
replication_samplesize: 286 children
study:
Novel loci involved in platelet function and platelet count identified by a genome-wide study performed in children.


dbdate: 06/01/2011
author: Kim DH
date: 05/03/2011
journal: Blood
link: http://www.ncbi.nlm.nih.gov/pubmed/21540461
trait: Chronic myeloid leukemia
initial_samplesize: 201 Korean ancestry cases, 497 Korean ancestry controls
study:
A genome-wide association study identifies novel loci associated with susceptibility to chronic myeloid leukemia.

replication_samplesize:
237 Korean ancestry cases, 1,000 Korean ancestry controls, 232 European ancestry cases, 576 European ancestry controls


dbdate: 06/01/2011
author: Burdon KP
date: 05/01/2011
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21532571
trait: Glaucoma
initial_samplesize: 590 European ancestry cases, 3,956 European ancestry controls
replication_samplesize: 892 European ancestry advanced cases, 4,582 European ancestry less severe cases
study:
Genome-wide association study identifies susceptibility loci for open angle glaucoma at TMCO1 and CDKN2B-AS1.


dbdate: 06/01/2011
author: Ramsuran V
date: 05/01/2011
journal: Clin Infect Dis
link: http://www.ncbi.nlm.nih.gov/pubmed/21507922
trait: Neutrophil count
initial_samplesize: 115 African ancestry HIV-negative individuals
study:
Duffy-null-associated low neutrophil counts influence HIV-1 susceptibility in high-risk South African black women.


dbdate: 05/28/2011
author: Heath AC
date: 04/27/2011
journal: Biol Psychiatry
link: http://www.ncbi.nlm.nih.gov/pubmed/21529783
trait: Alcoholism (12-month weekly alcohol consumption)
initial_samplesize: 2,062 European ancestry alcohol dependence cases, 6,692 European ancestry controls
replication_samplesize: 3,393 European ancestry individuals
study:
A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications.


dbdate: 05/27/2011
author: Duncan EL
date: 04/21/2011
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21533022
trait: Bone mineral density
replication_samplesize: 20,898 European ancestry females
study:
Genome-wide association study using extreme truncate selection identifies novel genes affecting bone mineral density and fracture risk.

initial_samplesize:
900 European ancestry females with low hip bone mineral density, 1,055 European ancestry females with high hip bone mineral density


dbdate: 05/27/2011
author: Pare G
date: 04/21/2011
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21533024
trait: Soluble ICAM-1
initial_samplesize: 22,435 European ancestry females
replication_samplesize: 9,813 Other ancestry individuals
study:
Genome-wide association analysis of soluble ICAM-1 concentration reveals novel associations at the NFKBIK, PNPLA3, RELA, and SH2B3 loci.


dbdate: 05/25/2011
author: Smedby KE
date: 04/21/2011
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21533074
trait: Follicular lymphoma
initial_samplesize: 379 European ancestry cases, 791 European ancestry controls
replication_samplesize: 1,049 European ancestry cases, 3,952 European ancestry controls
study:
GWAS of follicular lymphoma reveals allelic heterogeneity at 6p21.32 and suggests shared genetic susceptibility with diffuse large B-cell lymphoma.


dbdate: 05/26/2011
author: Dorajoo R
date: 04/19/2011
journal: Int J Obes (Lond)
link: http://www.ncbi.nlm.nih.gov/pubmed/21544081
study: Replication of 13 obesity loci among Singaporean Chinese, Malay and Asian-Indian populations.
trait: Obesity
initial_samplesize:
5,429 Chinese anacestry individuals, 2,431 Malay ancestry individuals, 2,531 Asian Indian ancestry individuals


dbdate: 05/13/2011
author: Li Z
date: 04/19/2011
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21505071
trait: Myopia (pathological)
initial_samplesize: 102 Han Chinese ancestry cases, 335 Han Chinese ancestry controls
replication_samplesize: 2,891 Han Chinese ancestry cases, 10,071 Han Chinese ancestry controls
study:
A genome-wide association study reveals association between common variants in an intergenic region of 4q25 and high-grade myopia in the Chinese Han population.


dbdate: 05/26/2011
author: Stein JL
date: 04/19/2011
journal: Mol Psychiatry
link: http://www.ncbi.nlm.nih.gov/pubmed/21502949
trait: Caudate nucleus volume
initial_samplesize: 734 European ancestry individuals
replication_samplesize: 464 European ancestry individuals
study:
Discovery and replication of dopamine-related gene effects on caudate volume in young and elderly populations (N=1198) using genome-wide search.


dbdate: 05/25/2011
author: Terao C
date: 04/19/2011
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21505073
trait: Rheumatoid arthritis
initial_samplesize: 1,247 Japanese ancestry cases, 1,486 Japanese ancestry controls
replication_samplesize: 4,168 Japanese ancestry cases, 5,003 Japanese ancestry controls
study:
The human AIRE gene at chromosome 21q22 is a genetic determinant for the predisposition to rheumatoid arthritis in Japanese population.


dbdate: 05/25/2011
author: Weber F
date: 04/19/2011
journal: Pharmacogenomics J
link: http://www.ncbi.nlm.nih.gov/pubmed/21502966
trait: Response to interferon beta therapy
study:
Single-nucleotide polymorphisms in HLA- and non-HLA genes associated with the development of antibodies to interferon-&#x003b2; therapy in multiple sclerosis patients.

initial_samplesize:
178 European ancestry antibody-positive individuals, 184 European ancestry antibody-negative individuals

replication_samplesize:
350 European ancestry antibody-positive individuals, 468 European ancestry antibody-negative individuals


dbdate: 05/11/2011
author: Kumar V
date: 04/17/2011
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21499248
trait: Hepatocellular carcinoma
initial_samplesize: 721 Japanese ancestry cases, 2,890 Japanese ancestry controls
replication_samplesize: 673 Japanese ancestry cases, 2,596 Japanese ancestry controls
study:
Genome-wide association study identifies a susceptibility locus for HCV-induced hepatocellular carcinoma.


dbdate: 05/24/2011
author: Spurdle AB
date: 04/17/2011
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21499250
trait: Endometrial cancer
initial_samplesize: 1,265 European ancestry cases, 5,190 European ancestry controls
replication_samplesize: 3,957 European ancestry cases, 6,886 European ancestry controls
study:
Genome-wide association study identifies a common variant associated with risk of endometrial cancer.


dbdate: 05/26/2011
author: Zhai G
date: 04/14/2011
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21533175
trait: Dehydroepiandrosterone sulphate levels
initial_samplesize: 14,846 European ancestry individuals
study:
Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms.


dbdate: 05/27/2011
author: Lucena MI
date: 04/12/2011
journal: Gastroenterology
link: http://www.ncbi.nlm.nih.gov/pubmed/21570397
trait: Drug-induced liver injury (amoxicillin-clavulanate)
initial_samplesize: 201 European ancestry cases, 532 European ancestry controls
study:
Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class I and II alleles.


dbdate: 05/11/2011
author: Wu X
date: 04/11/2011
journal: J Natl Cancer Inst
link: http://www.ncbi.nlm.nih.gov/pubmed/21483023
trait: Response to platinum-based chemotherapy in non-small-cell lung cancer
initial_samplesize: 327 European ancestry individuals
replication_samplesize: 735 European ancestry individuals
study:
Genome-wide association study of survival in non-small cell lung cancer patients receiving platinum-based chemotherapy.


dbdate: 05/11/2011
author: Nan H
date: 04/09/2011
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21478494
trait: Cutaneous nevi
initial_samplesize: 9,136 European ancestry individuals
replication_samplesize: 3,581 European ancestry individuals
study:
Genome-wide association study identifies nidogen 1 (NID1) as a susceptibility locus to cutaneous nevi and melanoma risk.


dbdate: 05/26/2011
author: Cornelis MC
date: 04/07/2011
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21490707
trait: Caffeine consumption
initial_samplesize: 47,431 European ancestry individuals
study:
Genome-wide meta-analysis identifies regions on 7p21 (AHR) and 15q24 (CYP1A2) as determinants of habitual caffeine consumption.


dbdate: 05/11/2011
author: Fliers EA
date: 04/07/2011
journal: World J Biol Psychiatry
link: http://www.ncbi.nlm.nih.gov/pubmed/21473668
trait: Attention deficit hyperactivity disorder motor coordination
initial_samplesize: 890 European ancestry children
replication_samplesize: 296 European ancestry children
study:
Genome-wide association study of motor coordination problems in ADHD identifies genes for brain and muscle function.


dbdate: 05/24/2011
author: Sim X
date: 04/07/2011
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21490949
study: Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia.
trait: Type 2 diabetes
initial_samplesize:
2,010 Chinese ancestry cases, 1,945 Chinese ancestry controls, 794 Malay ancestry cases, 1,240 Malay ancestry controls, 977 Asian Indian ancestry cases, 1,169 Asian Indian ancestry controls


dbdate: 05/24/2011
author: Schumann G
date: 04/06/2011
journal: Proc Natl Acad Sci U S A
link: http://www.ncbi.nlm.nih.gov/pubmed/21471458
trait: Alcohol consumption
initial_samplesize: 26,316 European ancestry individuals
replication_samplesize: 21,185 European ancestry individuals
study:
Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption.


dbdate: 05/02/2011
author: Cha PC
date: 04/03/2011
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21460842
trait: Uterine fibroids
initial_samplesize: 1,607 Japanese ancestry cases, 1,428 Japanese ancestry controls
replication_samplesize: 3,439 Japanese ancestry cases, 3,244 Japanese ancestry controls
study:
A genome-wide association study identifies three loci associated with susceptibility to uterine fibroids.


dbdate: 05/02/2011
author: Hollingworth P
date: 04/03/2011
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21460840
trait: Alzheimer's disease
initial_samplesize: 6,688 European ancestry cases, 13,685 European ancestry controls
replication_samplesize: 13,182 European ancestry cases, 26,161 European ancestry controls
study:
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.


dbdate: 05/24/2011
author: Naj AC
date: 04/03/2011
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21460841
trait: Alzheimer's disease (late onset)
initial_samplesize: 8,309 European ancestry cases, 7,366 European ancestry controls
replication_samplesize: 10,523 European ancestry cases, 28,231 European ancestry controls
study:
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.


dbdate: 04/29/2011
author: Gu J
date: 04/02/2011
journal: Cancer Prev Res (Phila)
link: http://www.ncbi.nlm.nih.gov/pubmed/21460395
trait: Telomere length
initial_samplesize: 459 Other ancestry individuals
replication_samplesize: 1,160 Other ancestry individuals
study:
A genome-wide association study identifies a locus on chromosome 14q21 as a predictor of leukocyte telomere length and as a marker of susceptibility for bladder cancer.


dbdate: 04/29/2011
author: Freudenberg J
date: 04/01/2011
journal: Arthritis Rheum
link: http://www.ncbi.nlm.nih.gov/pubmed/21452313
trait: Rheumatoid arthritis
initial_samplesize: 801 Korean ancestry cases, 757 Korean ancestry controls
replication_samplesize: 718 Korean ancestry cases, 719 Korean ancestry controls
study:
Genome-wide association study of rheumatoid arthritis in Koreans: population-specific loci as well as overlap with European susceptibility loci.


dbdate: 04/29/2011
author: Villard E
date: 04/01/2011
journal: Eur Heart J
link: http://www.ncbi.nlm.nih.gov/pubmed/21459883
trait: Dilated cardiomyopathy
initial_samplesize: 1,179 European ancestry cases, 1,108 European ancestry controls
replication_samplesize: 1,165 European ancestry cases, 1,302 European ancestry controls
study:
A genome-wide association study identifies two loci associated with heart failure due to dilated cardiomyopathy.


dbdate: 04/13/2011
author: Ligthart L
date: 03/30/2011
journal: Eur J Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21448238
study: Meta-analysis of genome-wide association for migraine in six population-based European cohorts.
trait: Migraine
replication_samplesize: 2,957 European ancestry cases, 5,774 European ancestry controls
initial_samplesize:
2,116 European ancestry cases, 7,318 European ancestry controls, 330 Dutch founder cases, 1,216 Dutch founder controls


dbdate: 04/13/2011
author: Miller EK
date: 03/25/2011
journal: Vaccine
link: http://www.ncbi.nlm.nih.gov/pubmed/21396408
trait: Vaccine-related adverse events
initial_samplesize: 6 European ancestry cases,55 European ancestry controls
study:
Atopy history and the genomics of wheezing after influenza vaccination in children 6-59 months of age.


dbdate: 04/23/2013
author: Deelen J
date: 03/21/2011
journal: Aging Cell
link: http://www.ncbi.nlm.nih.gov/pubmed/21418511
trait: Longevity
initial_samplesize: 403 European ancestry cases, 1,670 European ancestry controls
study:
Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited.

replication_samplesize:
1,578 European ancestry cases, 1,997 European ancestry controls, 1,208 Other ancestry cases, 2,090 Other ancestry controls, 960 cases, 1,825 controls


dbdate: 04/13/2011
author: Sehrawat B
date: 03/19/2011
journal: Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21424380
trait: Breast cancer
initial_samplesize: 302 European ancestry female cases, 321 European ancestry female controls
replication_samplesize: 1,153 European ancestry female cases, 1,215 European ancestry female controls
study:
Potential novel candidate polymorphisms identified in genome-wide association study for breast cancer susceptibility.


dbdate: 04/13/2011
author: McKay JD
date: 03/17/2011
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21437268
trait: Upper aerodigestive tract cancers
initial_samplesize: 2,091 European ancestry cases, 8,334 European ancestry controls
replication_samplesize: 6,574 European ancestry cases, 7,892 European ancestry controls
study:
A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium.


dbdate: 04/12/2011
author: Gharavi AG
date: 03/13/2011
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21399633
study: Genome-wide association study identifies susceptibility loci for IgA nephropathy.
trait: Nephropathy
initial_samplesize: 1,194 Han Chinese ancestry cases, 902 Han Chinese ancestry controls
replication_samplesize:
712 Han Chinese ancestry cases, 748 Han Chinese ancestry controls, 1,238 European ancestry cases, 1,172 European ancestry controls


dbdate: 04/11/2011
author: Speliotes EK
date: 03/10/2011
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21423719
trait: Nonalcoholic fatty liver disease
initial_samplesize: 880 Amish individuals, 6,296 European ancestry individuals
replication_samplesize: 592 European ancestry cases, 1,405 European ancestry controls
study:
Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits.


dbdate: 04/08/2011
author: Marciante KD
date: 03/06/2011
journal: Pharmacogenet Genomics
link: http://www.ncbi.nlm.nih.gov/pubmed/21386754
study: Cerivastatin, genetic variants, and the risk of rhabdomyolysis.
trait: Response to cerivastatin
initial_samplesize:
168 European ancestry cases, 17 Other ancestry cases, 636 European ancestry controls, 96 Other ancestry controls


dbdate: 04/11/2011
author: The Coronary Artery Disease (C4D) Genetics Consortium
date: 03/06/2011
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21378988
trait: Coronary heart disease
study:
A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease.

initial_samplesize:
8,424 European ancestry cases, 7,268 European ancestry controls, 6,996 South Asian ancestry cases, 7,794 South Asian ancestry controls

replication_samplesize:
18,049 European ancestry cases, 16,357 European ancestry controls, 3,359 South Asian ancestry cases, 2,828 South Asian ancestry controls


dbdate: 04/07/2011
author: Chung SA
date: 03/03/2011
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21408207
trait: Systemic lupus erythematosus
study:
Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.

initial_samplesize:
811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls


dbdate: 04/07/2011
author: Takeuchi F
date: 03/01/2011
journal: Circ J
link: http://www.ncbi.nlm.nih.gov/pubmed/21372407
trait: Drinking behavior
initial_samplesize: 733 Japanese ancestry cases, 729 Japanese ancestry controls
study:
Confirmation of ALDH2 as a Major locus of drinking behavior and of its variants regulating multiple metabolic phenotypes in a Japanese population.

replication_samplesize:
2,794 Japanese ancestry drinkers, 1,521 Japanese ancestry chance drinkers, 1,351 Japanese ancestry non-drinkers


dbdate: 04/30/2013
author: Kim Y
date: 02/28/2011
journal: World J Biol Psychiatry
link: http://www.ncbi.nlm.nih.gov/pubmed/23480133
trait: Vascular dementia
initial_samplesize: 84 Korean ancestry cases, 200 Korean ancestry controls
replication_samplesize: 113 Korean ancestry cases, 255 Korean ancestry controls
study:
Association of intronic sequence variant in the gene encoding spleen tyrosine kinase with susceptibility to vascular dementia.


dbdate: 04/06/2011
author: Bol SM
date: 02/25/2011
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/21364930
trait: HIV-1 replication
initial_samplesize: 191 European ancestry individuals
replication_samplesize: 31 individuals
study:
Genome-wide association study identifies single nucleotide polymorphism in DYRK1A associated with replication of HIV-1 in monocyte-derived macrophages.


dbdate: 04/06/2011
author: Hu X
date: 02/24/2011
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/21390209
trait: Alzheimer's disease (late onset)
initial_samplesize: 1,831 European ancestry cases, 1,764 European ancestry controls
replication_samplesize: 751 cases, 751 controls
study:
Meta-analysis for genome-wide association study identifies multiple variants at the BIN1 locus associated with late-onset Alzheimer's disease.


dbdate: 04/06/2011
author: Zhernakova A
date: 02/24/2011
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21383967
trait: Celiac disease and Rheumatoid arthritis
study:
Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci.

initial_samplesize:
4,533 European ancestry celiac disease cases, 5,539 European ancestry rheumatoid arthritis cases, 27,981 European ancestry controls

replication_samplesize:
2,169 European ancestry celiac disease cases, 2,845 European ancestry rheumatoid arthritis cases, European ancestry 7,199 controls


dbdate: 04/06/2011
author: Cichon S
date: 02/23/2011
journal: Am J Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21353194
trait: Bipolar disorder
initial_samplesize: 682 European ancestry cases, 1,300 European ancestry controls
replication_samplesize: 7,759 European ancestry cases, 34,062 European ancestry controls
study:
Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder.


dbdate: 04/06/2011
author: Liu X
date: 02/22/2011
journal: Mol Psychiatry
link: http://www.ncbi.nlm.nih.gov/pubmed/21339755
trait: 5-HTT brain serotonin transporter levels
initial_samplesize: 16 unmedicated bipolar disorder cases, 17 unmedicated major depressive disorder cases, 22 controls
replication_samplesize: 51 European ancestry individuals
study:
A non-synonymous polymorphism in galactose mutarotase (GALM) is associated with serotonin transporter binding potential in the human thalamus: results of a genome-wide association study.


dbdate: 04/04/2011
author: Bhatnagar P
date: 02/17/2011
journal: J Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21326311
trait: F-cell distribution
initial_samplesize: 440 African American individuals
study:
Genome-wide association study identifies genetic variants influencing F-cell levels in sickle-cell patients.


dbdate: 04/04/2011
author: Jin Y
date: 02/17/2011
journal: J Invest Dermatol
link: http://www.ncbi.nlm.nih.gov/pubmed/21326295
trait: Vitiligo
initial_samplesize: 1,339 European ancestry cases
replication_samplesize: 677 European ancestry cases
study:
Genome-wide analysis identifies a quantitative trait locus in the MHC class II region associated with generalized vitiligo age of onset.


dbdate: 04/04/2011
author: Wijsman EM
date: 02/17/2011
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21379329
trait: Alzheimer's disease (late onset)
initial_samplesize: 1,848 European ancestry affected individuals, 1,991 European ancestry unaffected individuals
study:
Genome-wide association of familial late-onset Alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE.

replication_samplesize:
231 Caribbean Hispanic cases, 187 Caribbean Hispanic controls, 386 European ancestry cases, 386 European ancestry controls


dbdate: 04/04/2011
author: Kendler KS
date: 02/11/2011
journal: Alcohol Clin Exp Res
link: http://www.ncbi.nlm.nih.gov/pubmed/21314694
trait: Alcohol dependence
initial_samplesize: 2,357 European ancestry individuals, 812 African American individuals
study:
Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.


dbdate: 04/07/2011
author: Lettre G
date: 02/10/2011
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21347282
trait: Coronary heart disease
initial_samplesize: 8,090 African American individuals
replication_samplesize: 8,849 African American or African-Caribbean ancestry individuals
study:
Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.


dbdate: 03/29/2011
author: Khor CC
date: 02/09/2011
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21307088
trait: Optic disc parameters
initial_samplesize: 2,132 Indian ancestry individuals, 2,313 Malay ancestry individuals
replication_samplesize: 9,326 European ancestry individuals
study:
Genome-wide association studies in Asians confirm the involvement of ATOH7 and TGFBR3, and further identify CARD10 as a novel locus influencing optic disc area.


dbdate: 03/23/2011
author: Huang YC
date: 02/08/2011
journal: Ophthalmology
link: http://www.ncbi.nlm.nih.gov/pubmed/21310492
study: Genome-wide association study of diabetic retinopathy in a Taiwanese population.
trait: Diabetic retinopathy
initial_samplesize:
174 Han Chinese ancestry Type 2 diabetics with diabetic retinopathy, 575 Han Chinese ancestry Type 2 diabetics without diabetic retinopathy, 100 Han Chinese ancestry controls


dbdate: 03/28/2011
author: Dehghan A
date: 02/07/2011
journal: Circulation
link: http://www.ncbi.nlm.nih.gov/pubmed/21300955
trait: C-reactive protein
initial_samplesize: 66,185 European ancestry individuals
replication_samplesize: 16,540 European ancestry individuals
study:
Meta-analysis of genome-wide association studies in &gt;80 000 subjects identifies multiple loci for C-reactive protein levels.


dbdate: 03/29/2011
author: Anderson CA
date: 02/06/2011
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21297633
trait: Ulcerative colitis
initial_samplesize: 6,687 European ancestry cases, 19,718 European ancestry controls
replication_samplesize: 9,628 European ancestry cases, 12,917 European ancestry controls
study:
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.


dbdate: 03/18/2011
author: Tsai FJ
date: 02/04/2011
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/21326860
trait: Kawasaki disease
initial_samplesize: 250 Han Chinese ancestry cases, 446 Han Chinese ancestry controls
replication_samplesize: 208 Han Chinese ancestry cases, 366 Han Chinese ancestry controls
study:
Identification of novel susceptibility Loci for kawasaki disease in a Han chinese population by a genome-wide association study.


dbdate: 03/18/2011
author: Nalls MA
date: 02/01/2011
journal: Lancet
link: http://www.ncbi.nlm.nih.gov/pubmed/21292315
trait: Parkinson's disease
initial_samplesize: 5,333 European ancestry cases, 12,019 European ancestry controls
replication_samplesize: 7,053 European ancestry cases, 9,007 European ancestry controls
study:
Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies.


dbdate: 03/28/2011
author: Parsa A
date: 02/01/2011
journal: Clin Transl Sci
link: http://www.ncbi.nlm.nih.gov/pubmed/21348951
trait: Cardiac hypertrophy
initial_samplesize: 851 Old Order Amish individuals
study:
Hypertrophy-associated polymorphisms ascertained in a founder cohort applied to heart failure risk and mortality.


dbdate: 01/20/2012
author: Chen X
date: 01/27/2011
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/21298047
trait: Substance dependence
initial_samplesize: 2,524 European ancestry individuals, 1,103 African ancestry individuals
study:
The nuclear transcription factor PKNOX2 is a candidate gene for substance dependence in European-origin women.


dbdate: 03/02/2011
author: Del Greco M F
date: 01/27/2011
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21273288
trait: Natriuretic peptide levels
initial_samplesize: 1,325 European ancestry individuals
replication_samplesize: 1,746 European ancestry individuals
study:
Genome-wide association analysis and fine mapping of NT-proBNP level provide novel insight into the role of the MTHFR-CLCN6-NPPA-NPPB gene cluster.


dbdate: 03/18/2011
author: Festen EA
date: 01/27/2011
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21298027
trait: Crohn's disease and celiac disease
study:
A meta-analysis of genome-wide association scans identifies IL18RAP, PTPN2, TAGAP, and PUS10 as shared risk loci for Crohn's disease and celiac disease.

initial_samplesize:
3,230 European ancestry Crohn's disease cases, 768 European ancestry celiac disease cases, 6,251 European ancestry controls

replication_samplesize:
1,835 European ancestry Crohn's disease cases, 3,149 European ancestry celiac disease cases, 6,383 European ancestry controls


dbdate: 02/23/2011
author: Reilly MP
date: 01/14/2011
journal: Lancet
link: http://www.ncbi.nlm.nih.gov/pubmed/21239051
trait: Coronary heart disease
study:
Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies.

initial_samplesize:
1,808 European ancestry AngCAD cases, 915 European ancestry AngCAD controls, 4,572 European ancestry AngCAD with MI cases, 2,739 European ancestry AngCAD without MI controls

replication_samplesize:
10,585 European ancestry AngCAD cases, 6,468 European ancestry AngCAD controls, 1,211 European ancestry AngCAD with MI cases, 905 European ancestry AngCAD without MI controls


dbdate: 02/23/2011
author: Ochi H
date: 01/12/2011
journal: J Gen Virol
link: http://www.ncbi.nlm.nih.gov/pubmed/21228123
trait: Response to hepatitis C treatment
initial_samplesize: 2,101 East Asian ancestry cases, 282 Japanese ancestry controls
study:
IL-28B predicts response to chronic hepatitis C therapy--fine-mapping and replication study in Asian populations.


dbdate: 03/04/2011
author: Wineinger NE
date: 01/11/2011
journal: BMC Med Genomics
link: http://www.ncbi.nlm.nih.gov/pubmed/21223598
trait: Aortic root size
initial_samplesize: 1,086 African American individuals
study:
Genome-wide joint SNP and CNV analysis of aortic root diameter in African Americans: the HyperGEN study.


dbdate: 01/27/2011
author: Kim JJ
date: 01/09/2011
journal: Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21221998
trait: Kawasaki disease
initial_samplesize: 186 Korean ancestry child cases, 600 Korean ancestry controls
replication_samplesize: 514 East Asian ancestry child cases, 1,042 East Asian ancestry controls
study:
A genome-wide association analysis reveals 1p31 and 2p13.3 as susceptibility loci for Kawasaki disease.


dbdate: 02/22/2011
author: Kaplan RC
date: 01/07/2011
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21216879
trait: Insulin-like growth factors
initial_samplesize: 10,280 European ancestry individuals
study:
A genome-wide association study identifies novel loci associated with circulating IGF-I and IGFBP-3.


dbdate: 01/27/2011
author: Sharma S
date: 01/07/2011
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21216876
trait: Adolescent idiopathic scoliosis
initial_samplesize: 1,113 individuals from 418 families
replication_samplesize: 562 European ancestry cases, 137 cases, 666 European ancestry controls, 2,126 controls
study:
Genome-wide association studies of adolescent idiopathic scoliosis suggest candidate susceptibility genes.


dbdate: 02/03/2011
author: Pichler I
date: 01/04/2011
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21208937
trait: Iron levels
initial_samplesize: Up to 5,633 European ancestry individuals
replication_samplesize: Up to 3,457 European ancestry individuals
study:
Identification of a common variant in the TFR2 gene implicated in the physiological regulation of serum iron levels.


dbdate: 01/16/2011
author: Okada Y
date: 12/31/2010
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21196492
trait: C-reactive protein
initial_samplesize: 10,112 Japanese ancestry individuals
replication_samplesize: 2,742 Japanese ancestry individuals
study:
Genome-wide association study for C-reactive protein levels identified pleiotropic associations in the IL6 locus.


dbdate: 01/15/2011
author: Lauc G
date: 12/23/2010
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21203500
trait: N-glycan levels
initial_samplesize: 2,559 European ancestry individuals
study:
Genomics meets glycomics-the first GWAS study of human N-Glycome identifies HNF1&#x003b1; as a master regulator of plasma protein fucosylation.


dbdate: 01/18/2011
author: Moyer AM
date: 12/22/2010
journal: Toxicol Sci
link: http://www.ncbi.nlm.nih.gov/pubmed/21177773
study: Acetaminophen-NAPQI hepatotoxicity: a cell line model system genome-wide association study.
trait: Response to acetaminophen (hepatotoxicity)
initial_samplesize:
60 European ancestry lymphoblastoid cell lines, 56 African American lymphoblastoid cell lines, 60 Han Chinese American lymphoblastoid cell lines


dbdate: 07/02/2014
author: Padyukov L
date: 12/14/2010
journal: Ann Rheum Dis
link: http://www.ncbi.nlm.nih.gov/pubmed/21156761
trait: Rheumatoid arthritis
replication_samplesize: 887 European ancestry ACPA positive RA cases, 1,218 European ancestry controls
study:
A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis.

initial_samplesize:
1,147 European ancestry ACPA positive RA cases, 774 European ancestry ACPA negative RA cases, 1,079 European ancestry controls


dbdate: 01/19/2011
author: Petrovski S
date: 12/14/2010
journal: AIDS
link: http://www.ncbi.nlm.nih.gov/pubmed/21160409
trait: HIV-1 susceptibility
initial_samplesize: 531 Sub-Saharan African ancestry cases, 848 Sub-Saharan African ancestry controls
study:
Common human genetic variants and HIV-1 susceptibility: a genome-wide survey in a homogeneous African population.


dbdate: 01/16/2011
author: Chen ZJ
date: 12/12/2010
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21151128
trait: Polycystic ovary syndrome
initial_samplesize: 744 Han Chinese ancestry cases, 895 Han Chinese ancestry controls
replication_samplesize: 3,338 Han Chinese ancestry cases, 5,792 Han Chinese ancestry controls
study:
Genome-wide association study identifies susceptibility loci for polycystic ovary syndrome on chromosome 2p16.3, 2p21 and 9q33.3.


dbdate: 01/15/2011
author: Melum E
date: 12/12/2010
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21151127
trait: Primary sclerosing cholangitis
initial_samplesize: 715 European ancestry cases, 2,962 European ancestry controls
replication_samplesize: 1,025 European ancestry cases, 2,174 European ancestry controls
study:
Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci.


dbdate: 01/14/2011
author: Carrasquillo MM
date: 12/10/2010
journal: Am J Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21087763
trait: Progranulin levels
initial_samplesize: 518 European ancestry controls
replication_samplesize: 459 European ancestry controls
study:
Genome-wide screen identifies rs646776 near sortilin as a regulator of progranulin levels in human plasma.


dbdate: 01/15/2011
author: Oexle K
date: 12/10/2010
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21149283
trait: Iron status biomarkers
initial_samplesize: Up to 6,616 individuals
study:
Novel association to the proprotein convertase PCSK7 gene locus revealed by analysing soluble transferrin receptor (sTfR) levels.


dbdate: 01/11/2011
author: Ferreira MA
date: 12/08/2010
journal: Eur J Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21150878
trait: Asthma
initial_samplesize: 986 European ancestry cases, 1,846 European ancestry controls
replication_samplesize: 391 European ancestry cases, 213 European ancestry controls
study:
Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.


dbdate: 01/11/2011
author: Walsh KM
date: 12/07/2010
journal: Endocr Relat Cancer
link: http://www.ncbi.nlm.nih.gov/pubmed/21139019
trait: Ileal carcinoids
initial_samplesize: 239 European ancestry cases, 107 European ancestry controls
study:
A pilot genome-wide association study shows genomic variants enriched in the non-tumor cells of patients with well-differentiated neuroendocrine tumors of the ileum.


dbdate: 01/15/2011
author: Purdue MP
date: 12/05/2010
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21131975
trait: Renal cell carcinoma
initial_samplesize: 3,772 European ancestry cases, 8,505 European ancestry controls
replication_samplesize: 2,198 European ancestry cases, 4,918 European ancestry controls
study:
Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3.


dbdate: 01/10/2011
author: Clifford RJ
date: 12/01/2010
journal: Hepatology
link: http://www.ncbi.nlm.nih.gov/pubmed/21105107
trait: Hepatocellular carcinoma
initial_samplesize: 180 Korean ancestry cases, 271 Korean ancestry controls
replication_samplesize: 206 Korean ancestry cases, 416 East Asian ancestry controls,
study:
Genetic variations at loci involved in the immune response are risk factors for hepatocellular carcinoma.


dbdate: 01/12/2011
author: Kim S
date: 12/01/2010
journal: Neurology
link: http://www.ncbi.nlm.nih.gov/pubmed/21123754
study: Genome-wide association study of CSF biomarkers Abeta1-42, t-tau, and p-tau181p in the ADNI cohort.
trait: Alzheimer's disease biomarkers
initial_samplesize:
96 European ancestry Alzheimer disease cases, 176 European ancestry individuals with mild cognitive impairment, 102 European ancestry controls


dbdate: 07/01/2014
author: Mick E
date: 12/01/2010
journal: Prog Neuropsychopharmacol Biol Psychiatry
link: http://www.ncbi.nlm.nih.gov/pubmed/21130132
trait: Response to methylphenidate treatment in attention-deficit/hyperactivity disorder (blood pressure)
initial_samplesize: 140 child cases
study:
Genome-wide association study of blood pressure response to methylphenidate treatment of attention-deficit/hyperactivity disorder.


dbdate: 01/12/2011
author: Furney SJ
date: 11/30/2010
journal: Mol Psychiatry
link: http://www.ncbi.nlm.nih.gov/pubmed/21116278
trait: Entorhinal cortical thickness
study:
Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease.

initial_samplesize:
Up to 434 European ancestry MCI cases, 245 European ancestry AD cases, 284 European ancestry controls


dbdate: 12/09/2010
author: Wu C
date: 11/30/2010
journal: Cancer Res
link: http://www.ncbi.nlm.nih.gov/pubmed/21118971
trait: Small-cell lung cancer (survival)
initial_samplesize: 245 Han Chinese ancestry cases
replication_samplesize: 305 Han Chinese ancestry cases
study:
Genome-wide interrogation identifies YAP1 variants associated with survival of small-cell lung cancer patients.


dbdate: 01/08/2011
author: van der Zanden LF
date: 11/28/2010
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21113153
study: Common variants in DGKK are strongly associated with risk of hypospadias.
trait: Hypospadias
initial_samplesize: 436 European ancestry cases, 494 European ancestry controls
replication_samplesize:
133 European ancestry cases and their parents, 266 European ancestry cases, 402 European ancestry controls


dbdate: 01/08/2011
author: McClay JL
date: 11/24/2010
journal: Neuropsychopharmacology
link: http://www.ncbi.nlm.nih.gov/pubmed/21107309
trait: Response to antipsychotic treatment
initial_samplesize: 738 European ancestry, African-American, and other ancestry cases
study:
Genome-wide pharmacogenomic study of neurocognition as an indicator of antipsychotic treatment response in schizophrenia.


dbdate: 07/01/2014
author: Elks CE
date: 11/21/2010
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21102462
trait: Menarche (age at onset)
initial_samplesize: 86,142 European ancestry women, 557 Old Order Amish women, 1,103 Erasmus Rucphen women
study:
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies.

replication_samplesize:
Up to 12,813 European ancestry women, 910 Val Borbera women, 348 Orcadian women, 338 Friuli Venezia Giulia women, 322 Carlantino women


dbdate: 10/19/2012
author: Franke A
date: 11/21/2010
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21102463
trait: Crohn's disease
initial_samplesize: 6,333 European ancestry cases, 15,056 European ancestry controls
study:
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.

replication_samplesize:
15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry parent-offspring trios


dbdate: 01/07/2011
author: Li YJ
date: 11/20/2010
journal: Ophthalmology
link: http://www.ncbi.nlm.nih.gov/pubmed/21095009
trait: Myopia (pathological)
replication_samplesize: 959 Japanese ancestry cases, 2,128 Japanese ancestry controls
study:
Genome-wide association studies reveal genetic variants in CTNND2 for high myopia in Singapore Chinese.

initial_samplesize:
65 Singaporean Chinese child cases, 238 Singaporean Chinese child controls, 222 Singaporean Chinese adult cases, 455 Singaporean Chinese adult cases


dbdate: 01/06/2011
author: Erdmann J
date: 11/18/2010
journal: Eur Heart J
link: http://www.ncbi.nlm.nih.gov/pubmed/21088011
trait: Coronary heart disease
initial_samplesize: 1,157 European ancestry cases, 1,748 European ancestry controls
replication_samplesize: 7,887 European ancestry cases, 8,244 European ancestry controls
study:
Genome-wide association study identifies a new locus for coronary artery disease on chromosome 10p11.23.


dbdate: 06/24/2014
author: Marzi C
date: 11/18/2010
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21124955
trait: Amyloid A serum levels
initial_samplesize: 3,329 European ancestry individuals, 882 Sorbian individuals
replication_samplesize: 2,136 European ancestry individuals
study:
Genome-wide association study identifies two novel regions at 11p15.5-p13 and 1p31 with major impact on acute-phase serum amyloid A.


dbdate: 01/12/2011
author: Paternoster L
date: 11/18/2010
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21124946
trait: Bone mineral density
initial_samplesize: 1,934 European ancestry individuals
replication_samplesize: Up to 3,835 European ancestry individuals
study:
Genome-wide association meta-analysis of cortical bone mineral density unravels allelic heterogeneity at the RANKL locus and potential pleiotropic effects on bone.


dbdate: 01/06/2011
author: Saad M
date: 11/17/2010
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21084426
trait: Parkinson's disease
initial_samplesize: 1,039 European ancestry cases, 1,984 European ancestry controls
replication_samplesize: 3,232 European ancestry cases, 7,064 European ancestry controls
study:
Genome-wide association study confirms BST1 and suggests a locus on 12q24 as the risk loci for Parkinson's disease in the European population.


dbdate: 12/09/2010
author: Sato Y
date: 11/12/2010
journal: J Thorac Oncol
link: http://www.ncbi.nlm.nih.gov/pubmed/21079520
trait: Non-small cell lung cancer (survival)
initial_samplesize: 105 East Asian ancestry cases
study:
Genome-wide association study on overall survival of advanced non-small cell lung cancer patients treated with carboplatin and paclitaxel.


dbdate: 01/06/2011
author: Evangelou E
date: 11/10/2010
journal: Ann Rheum Dis
link: http://www.ncbi.nlm.nih.gov/pubmed/21068099
trait: Osteoarthritis
initial_samplesize: 2,371 European ancestry cases, 35,909 European ancestry controls
study:
Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22.

replication_samplesize:
4,338 European ancestry cases, 8,530 European ancestry controls, 1,183 East Asian ancestry cases, 1,245 East Asian ancestry controls


dbdate: 01/14/2011
author: Shen H
date: 11/08/2010
journal: Arch Intern Med
link: http://www.ncbi.nlm.nih.gov/pubmed/21059979
trait: LDL cholesterol
initial_samplesize: 841 Amish individuals
replication_samplesize: 663 Amish inidividuals
study:
Familial defective apolipoprotein B-100 and increased low-density lipoprotein cholesterol and coronary artery calcification in the old order amish.


dbdate: 08/02/2011
author: Agrawal A
date: 11/04/2010
journal: Addict Biol
link: http://www.ncbi.nlm.nih.gov/pubmed/21668797
study: A genome-wide association study of DSM-IV cannabis dependence.
trait: Cannabis dependence
initial_samplesize:
708 African American or European ancestry cases, 2,346 African American or European ancestry controls


dbdate: 01/11/2011
author: Curtis D
date: 11/04/2010
journal: Psychiatr Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21057379
trait: Bipolar disorder and schizophrenia
study:
Case-case genome-wide association analysis shows markers differentially associated with schizophrenia and bipolar disorder and implicates calcium channel genes.

initial_samplesize:
506 European ancestry bipolar 1 disorder cases, 523 European ancestry schizophrenia cases, 505 European ancestry controls


dbdate: 01/13/2011
author: Pereyra F
date: 11/04/2010
journal: Science
link: http://www.ncbi.nlm.nih.gov/pubmed/21051598
study: The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.
trait: HIV-1 control
initial_samplesize:
516 European cases, 1,196 European controls, 341 African American cases, 892 African American controls, 117 Hispanic ancestry controls, 560 Hispanic ancestry controls


dbdate: 01/03/2011
author: Spencer CC
date: 11/02/2010
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21044948
trait: Parkinson's disease
initial_samplesize: 1,705 European ancestry cases, 5,175 European ancestry controls
replication_samplesize: 1,039 European ancestry cases, 1,984 European ancestry controls
study:
Dissection of the genetics of Parkinson's disease identifies an additional association 5' of SNCA and multiple associated haplotypes at 17q21.


dbdate: 01/04/2011
author: Wray NR
date: 11/02/2010
journal: Mol Psychiatry
link: http://www.ncbi.nlm.nih.gov/pubmed/21042317
trait: Major depressive disorder
initial_samplesize: 2,431 European ancestry cases, 3,673 European ancestry controls
replication_samplesize: 3,332 European ancestry cases, 3,228 European ancestry controls
study:
Genome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learned.


dbdate: 01/03/2011
author: Yang J
date: 11/02/2010
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21044949
study: ELF1 is associated with systemic lupus erythematosus in Asian populations.
trait: Systemic lupus erythematosus
initial_samplesize: 612 Chinese ancestry cases, 1,160 Chinese ancestry controls
replication_samplesize:
2,090 Chinese ancestry cases, 1,981 Chinese ancestry controls, 462 Thai ancestry cases, 951 Thai ancestry controls


dbdate: 01/03/2011
author: Zlojutro M
date: 11/02/2010
journal: Am J Med Genet B Neuropsychiatr Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21184583
trait: Event-related brain oscillations
replication_samplesize: 683 alcohol dependence cases and 412 controls from multiplex families
study:
Genome-wide association study of theta band event-related oscillations identifies serotonin receptor gene HTR7 influencing risk of alcohol dependence.

initial_samplesize:
431 European ancestry alcohol dependence cases, 340 European ancestry controls, 209 African American alcohol dependence cases, 84 African American controls


dbdate: 01/03/2011
author: Denny JC
date: 11/01/2010
journal: Circulation
link: http://www.ncbi.nlm.nih.gov/pubmed/21041692
trait: Atrioventricular conduction
initial_samplesize: 2,334 European ancestry individuals
study:
Identification of genomic predictors of atrioventricular conduction: using electronic medical records as a tool for genome science.


dbdate: 08/20/2013
author: Haritunians T
date: 11/01/2010
journal: Inflamm Bowel Dis
link: http://www.ncbi.nlm.nih.gov/pubmed/20848476
study: Genetic predictors of medically refractory ulcerative colitis.
trait: Ulcerative colitis
initial_samplesize:
324 European ancestry medically refractory ulcerative colitis cases, 537 European ancestry non-medically refractory ulcerative colitis cases, 2,601 European ancestry controls


dbdate: 01/07/2014
author: Perlis RH
date: 11/01/2010
journal: Am J Psychiatry
link: http://www.ncbi.nlm.nih.gov/pubmed/21041247
study: Genome-wide association study of suicide attempts in mood disorder patients.
trait: Suicide risk
replication_samplesize: 2,698 European ancestry Bipolar disorder cases, 1,649 Major depressive disorder cases
initial_samplesize:
3,117 European ancestry Bipolar disorder cases, 1,273 European ancestry Major depressive disorder cases


dbdate: 01/03/2011
author: Enciso-Mora V
date: 10/31/2010
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21037568
trait: Hodgkin's lymphoma
initial_samplesize: 589 European ancestry cases, 5,199 European ancestry controls
replication_samplesize: 2,057 European ancestry cases, 3,416 European ancestry controls
study:
A genome-wide association study of Hodgkin's lymphoma identifies new susceptibility loci at 2p16.1 (REL), 8q24.21 and 10p14 (GATA3).


dbdate: 12/16/2010
author: Padmanabhan S
date: 10/28/2010
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/21082022
trait: Hypertension
initial_samplesize: 1,621 extreme cases, 1,699 controls
replication_samplesize: 19,845 extreme cases, 16,541 controls
study:
Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension.


dbdate: 12/09/2010
author: Houlston RS
date: 10/24/2010
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20972440
trait: Colorectal cancer
initial_samplesize: 3,334 European ancestry cases, 4,628 European ancestry controls
replication_samplesize: 14,851 European ancestry cases, 15,569 European ancestry controls
study:
Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33.


dbdate: 12/08/2010
author: Rothman N
date: 10/24/2010
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20972438
trait: Bladder cancer
initial_samplesize: 3,532 European ancestry cases, 5,120 European ancestry controls
replication_samplesize: 8,381 cases, 48,275 controls
study:
A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci.


dbdate: 12/03/2010
author: Croteau-Chonka DC
date: 10/21/2010
journal: Obesity (Silver Spring)
link: http://www.ncbi.nlm.nih.gov/pubmed/20966902
trait: Body mass index
initial_samplesize: 1,780 Filipino ancestry women
study:
Genome-wide association study of anthropometric traits and evidence of interactions with age and study year in Filipino women.


dbdate: 12/01/2010
author: Ellinghaus E
date: 10/17/2010
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20953188
study: Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2.
trait: Psoriasis
initial_samplesize: 472 European ancestry cases, 1,146 European ancestry controls
replication_samplesize:
2,668, European ancestry cases, 762 French Canadian founder population cases, 2,585 cases, 3,485 European ancestry controls, 994 French Canadian founder population controls, 2,412 controls


dbdate: 11/30/2010
author: Huffmeier U
date: 10/17/2010
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20953186
trait: Psoriatic arthritis
initial_samplesize: 572 European ancestry cases, 888 European ancestry controls
replication_samplesize: Up to 1,761 European ancestry cases, 3,727 European ancestry controls
study:
Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis.


dbdate: 01/18/2011
author: Strange A
date: 10/17/2010
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20953190
trait: Psoriasis
initial_samplesize: 2,178 European ancestry cases, 5,175 European ancestry controls
replication_samplesize: 3,174 European ancestry cases, 5,464 European ancestry controls
study:
A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.


dbdate: 11/17/2010
author: Heid IM
date: 10/10/2010
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20935629
trait: Waist-hip ratio
initial_samplesize: Up to 77,167 European ancestry individuals
replication_samplesize: Up to 113,636 European ancestry individuals
study:
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.


dbdate: 11/23/2010
author: Han MR
date: 10/08/2010
journal: BMC Neurol
link: http://www.ncbi.nlm.nih.gov/pubmed/20932310
trait: Cerebrospinal AB1-42 levels
study:
Genome-wide association reveals genetic effects on human A&#x003b2;42 and &#x003c4; protein levels in cerebrospinal fluids: a case control study.

initial_samplesize:
172 European ancestry Alzheimer's disease cases, 109 European ancestry mild cognitive impairment cases, 109 European ancestry controls


dbdate: 11/15/2010
author: Kerns SL
date: 10/05/2010
journal: Int J Radiat Oncol Biol Phys
link: http://www.ncbi.nlm.nih.gov/pubmed/20932654
trait: Erectile dysfunction and prostate cancer treatment
initial_samplesize: 27 African American cases, 52 African American controls
study:
Genome-wide association study to identify single nucleotide polymorphisms (SNPs) associated with the development of erectile dysfunction in African-American men after radiotherapy for prostate cancer.


dbdate: 11/23/2010
author: Niu N
date: 10/05/2010
journal: Genome Res
link: http://www.ncbi.nlm.nih.gov/pubmed/20923822
trait: Radiation response
study:
Radiation pharmacogenomics: a genome-wide association approach to identify radiation response biomarkers using human lymphoblastoid cell lines.

initial_samplesize:
Human lymphoblastoid cell lines; 93 of African American, 89 of European ancestry, and 95 of Han Chinese American ancestry


dbdate: 01/14/2011
author: Shatunov A
date: 10/01/2010
journal: Lancet Neurol
link: http://www.ncbi.nlm.nih.gov/pubmed/20801717
trait: Amyotrophic lateral sclerosis
initial_samplesize: 4,857 European ancestry cases, 8,987 European ancestry controls
study:
Chromosome 9p21 in sporadic amyotrophic lateral sclerosis in the UK and seven other countries: a genome-wide association study.


dbdate: 11/02/2012
author: Wang KS
date: 10/01/2010
journal: Schizophr Res
link: http://www.ncbi.nlm.nih.gov/pubmed/20889312
trait: Bipolar disorder and schizophrenia
study:
A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.

initial_samplesize:
651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls


dbdate: 10/15/2010
author: Yang Q
date: 09/30/2010
journal: Circ Cardiovasc Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20884846
trait: Urate levels
initial_samplesize: 28,283 European ancestry individuals
replication_samplesize: 22,054 European ancestry individuals
study:
Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors.


dbdate: 10/15/2010
author: Perroud N
date: 09/28/2010
journal: Pharmacogenomics J
link: http://www.ncbi.nlm.nih.gov/pubmed/20877300
trait: Suicidal ideation
initial_samplesize: 706 European ancestry individuals
study:
Genome-wide association study of increasing suicidal ideation during antidepressant treatment in the GENDEP project.


dbdate: 10/15/2010
author: Yoon KA
date: 09/28/2010
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20876614
trait: Non-small cell lung cancer
initial_samplesize: 621 Korean ancestry cases, 1,541 Korean ancestry controls
replication_samplesize: 804 Korean ancestry cases, 1,470 Korean ancestry controls
study:
A genome-wide association study reveals susceptibility variants for non-small cell lung cancer in the Korean population.


dbdate: 10/15/2010
author: Ingle JN
date: 09/27/2010
journal: J Clin Oncol
link: http://www.ncbi.nlm.nih.gov/pubmed/20876420
trait: Adverse response to aromatase inhibitors
initial_samplesize: 293 cases, 585 controls
study:
Genome-wide associations and functional genomic studies of musculoskeletal adverse events in women receiving aromatase inhibitors.


dbdate: 10/07/2010
author: Wu Y
date: 09/27/2010
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20876611
trait: Adiponectin levels
initial_samplesize: 1,776 Filipino ancestry women
replication_samplesize: 1,774 independent Filipino ancestry offspring
study:
Genome-wide association study for adiponectin levels in Filipino women identifies CDH13 and a novel uncommon haplotype at KNG1-ADIPOQ.


dbdate: 10/07/2010
author: Miki D
date: 09/26/2010
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20871597
trait: Lung adenocarcinoma
initial_samplesize: 1,004 Japanese ancestry cases, 1,900 Japanese ancestry controls
replication_samplesize: 1,094 East Asian ancestry cases, 9,148 East Asian ancestry controls
study:
Variation in TP63 is associated with lung adenocarcinoma susceptibility in Japanese and Korean populations.


dbdate: 10/14/2010
author: Kopplin LJ
date: 09/23/2010
journal: Genes Immun
link: http://www.ncbi.nlm.nih.gov/pubmed/20861866
trait: Age-related macular degeneration
initial_samplesize: 684 European ancestry cases, 188 European ancestry controls
replication_samplesize: 1,896 European ancestry cases, 1,866 European ancestry controls
study:
Genome-wide association identifies SKIV2L and MYRIP as protective factors for age-related macular degeneration.


dbdate: 10/14/2010
author: Naj AC
date: 09/23/2010
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20885792
trait: Alzheimer's disease (late onset)
initial_samplesize: 931 cases, 1,104 controls
replication_samplesize: 1,338 cases, 2,003 controls
study:
Dementia revealed: novel chromosome 6 locus for late-onset Alzheimer disease provides genetic evidence for folate-pathway abnormalities.


dbdate: 10/07/2010
author: Soranzo N
date: 09/21/2010
journal: Diabetes
link: http://www.ncbi.nlm.nih.gov/pubmed/20858683
trait: Glycated hemoglobin levels
initial_samplesize: up to 46,368 European ancestry individuals
study:
Common variants at 10 genomic loci influence hemoglobin A&#x02081;(C) levels via glycemic and nonglycemic pathways.


dbdate: 10/07/2010
author: Antoniou AC
date: 09/19/2010
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20852631
trait: Breast cancer
initial_samplesize: 1,193 European ancestry cases, 1,190 European ancestry controls
replication_samplesize: 2,974 European ancestry cases, 3,012 European ancestry controls
study:
A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population.


dbdate: 10/06/2010
author: Adachi S
date: 09/16/2010
journal: J Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20844546
trait: Endometriosis
initial_samplesize: 696 Japanese ancestry cases, 825 Japanese ancestry controls
study:
Meta-analysis of genome-wide association scans for genetic susceptibility to endometriosis in Japanese population.


dbdate: 10/05/2010
author: Franklin CS
date: 09/16/2010
journal: Ann Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20849430
trait: Glycated hemoglobin levels
initial_samplesize: 1,782 European ancestry individuals
study:
The TCF7L2 diabetes risk variant is associated with HbA&#x02081;(C) levels: a genome-wide association meta-analysis.


dbdate: 10/12/2010
author: Shu XO
date: 09/16/2010
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20862305
study: Identification of new genetic risk variants for type 2 diabetes.
trait: Type 2 diabetes
initial_samplesize: 1,019 Chinese ancestry cases, 1,710 Chinese ancestry controls
replication_samplesize:
2,591 European ancestry cases, 3,052 European ancestry controls, 6,184 East Asian cases, 9,853 East Asian controls


dbdate: 10/05/2010
author: Hysi PG
date: 09/12/2010
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20835236
trait: Refractive error
initial_samplesize: 4,270 European ancestry individuals
replication_samplesize: 13,414 European ancestry individuals
study:
A genome-wide association study for myopia and refractive error identifies a susceptibility locus at 15q25.


dbdate: 10/05/2010
author: Solouki AM
date: 09/12/2010
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20835239
trait: Refractive error
initial_samplesize: 5,328 European ancestry individuals
replication_samplesize: 10,280 European ancestry individuals
study:
A genome-wide association study identifies a susceptibility locus for refractive errors and myopia at 15q14.


dbdate: 10/05/2010
author: Cha PC
date: 09/10/2010
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20833655
trait: Warfarin maintenance dose
initial_samplesize: 807 low dose Japanese ancestry individuals, 701 high dose Japanese ancestry individuals
replication_samplesize: 444 individuals
study:
Genome-wide association study identifies genetic determinants of warfarin responsiveness for Japanese.


dbdate: 09/28/2010
author: Smith EN
date: 09/09/2010
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20838585
trait: Cardiovascular disease risk factors
initial_samplesize: 525 European ancestry individuals
replication_samplesize: 2,265 European ancestry individuals
study:
Longitudinal genome-wide association of cardiovascular disease risk factors in the Bogalusa heart study.


dbdate: 09/28/2010
author: Yamauchi T
date: 09/05/2010
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20818381
trait: Type 2 diabetes
initial_samplesize: 4,470 Japanese ancestry cases, 3,071 Japanese ancestry controls
study:
A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B.

replication_samplesize:
10,692 Japanese ancestry cases, 9,597 Japanese ancestry controls, 6,980 European ancestry cases, 8,615 European ancestry controls


dbdate: 09/27/2010
author: Baranzini SE
date: 09/01/2010
journal: Brain
link: http://www.ncbi.nlm.nih.gov/pubmed/20802204
trait: Multiple sclerosis--Brain Glutamate Levels
initial_samplesize: 382 cases
study:
Genetic variation influences glutamate concentrations in brains of patients with multiple sclerosis.


dbdate: 09/24/2010
author: Uhl GR
date: 08/24/2010
journal: Mol Med
link: http://www.ncbi.nlm.nih.gov/pubmed/20811658
trait: Smoking cessation
initial_samplesize: 369 European ancestry individuals
study:
Genome-wide association for smoking cessation success in a trial of precessation nicotine replacement.


dbdate: 09/23/2010
author: Abnet CC
date: 08/22/2010
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20729852
trait: Esophageal cancer and gastric cancer
study:
A shared susceptibility locus in PLCE1 at 10q23 for gastric adenocarcinoma and esophageal squamous cell carcinoma.

initial_samplesize:
1,625 Chinese ancestry gastric cancer cases, 1,898 Chinese ancestry ESCC cases, 2,100 Chinese ancestry controls


dbdate: 09/22/2010
author: Huang J
date: 08/16/2010
journal: Am J Psychiatry
link: http://www.ncbi.nlm.nih.gov/pubmed/20713499
study: Cross-disorder genomewide analysis of schizophrenia, bipolar disorder, and depression.
trait: Schizophrenia, bipolar disorder and depression (combined)
initial_samplesize:
402 European ancestry schizophrenia cases, 1,021 European ancestry bipolar I cases, 493 European ancestry bipolar II cases, 1,210 European ancestry MDD cases, 1,060 European ancestry controls


dbdate: 09/22/2010
author: Hamza TH
date: 08/15/2010
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20711177
trait: Parkinson's disease
initial_samplesize: 2,000 European ancestry cases, 1,986 European ancestry controls
replication_samplesize: Up to 1,447 cases, 1,468 controls
study:
Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease.


dbdate: 09/22/2010
author: Hor H
date: 08/15/2010
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20711174
trait: Narcolepsy
initial_samplesize: 562 European ancestry cases, 702 European ancestry controls
replication_samplesize: 370 cases, 495 controls
study:
Genome-wide association study identifies new HLA class II haplotypes strongly protective against narcolepsy.


dbdate: 09/22/2010
author: Nakashima M
date: 08/15/2010
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20711176
trait: Keloid
initial_samplesize: 178 Japanese ancestry cases, 906 Japanese ancestry controls
replication_samplesize: 621 Japanese ancestry cases, 2,271 Japanese ancestry controls
study:
A genome-wide association study identifies four susceptibility loci for keloid in the Japanese population.


dbdate: 09/21/2010
author: O'Seaghdha CM
date: 08/12/2010
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20705733
trait: Calcium levels
initial_samplesize: 20,611 European ancestry individuals
study:
Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels.


dbdate: 09/24/2010
author: Chalasani N
date: 08/10/2010
journal: Gastroenterology
link: http://www.ncbi.nlm.nih.gov/pubmed/20708005
trait: Non-alcoholic fatty liver disease histology (AST)
initial_samplesize: 236 European Ancestry cases
study:
Genome-wide association study identifies variants associated with histologic features of nonalcoholic Fatty liver disease.


dbdate: 09/15/2010
author: Davila S
date: 08/08/2010
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20694013
trait: Meningococcal disease
initial_samplesize: 475 European ancestry cases, 4,703 European ancestry controls
replication_samplesize: 929 European ancestry cases, 1,351 European ancestry controls
study:
Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease.


dbdate: 09/16/2010
author: Thye T
date: 08/08/2010
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20694014
trait: Tuberculosis
initial_samplesize: 2,237 Sub-Saharan African ancestry cases, 3,122 Sub-Saharan African ancestry controls
replication_samplesize: 1,462 Sub-Saharan African ancestry cases, 4,604 Sub-Saharan African ancestry controls
study:
Genome-wide association analyses identifies a susceptibility locus for tuberculosis on chromosome 18q11.2.


dbdate: 09/15/2010
author: Meyer TE
date: 08/05/2010
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20700443
trait: Magnesium levels
initial_samplesize: 15,366 European ancestry individuals
replication_samplesize: 8,463 European ancestry individuals
study:
Genome-wide association studies of serum magnesium, potassium, and sodium concentrations identify six Loci influencing serum magnesium levels.


dbdate: 09/14/2010
author: Verweij KJ
date: 08/04/2010
journal: Biol Psychol
link: http://www.ncbi.nlm.nih.gov/pubmed/20691247
trait: Personality dimensions
initial_samplesize: 5,117 European ancestry individuals from 2567 families
study:
A genome-wide association study of Cloninger's temperament scales: implications for the evolutionary genetics of personality.


dbdate: 08/16/2013
author: Dubinsky MC
date: 08/01/2010
journal: Inflamm Bowel Dis
link: http://www.ncbi.nlm.nih.gov/pubmed/20014019
trait: Response to anti-TNF alpha therapy in inflammatory bowel disease
initial_samplesize: 94 Other ancestry pediatric cases
study:
Genome wide association (GWA) predictors of anti-TNFalpha therapeutic responsiveness in pediatric inflammatory bowel disease.


dbdate: 09/11/2010
author: Takata R
date: 08/01/2010
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20676098
trait: Prostate cancer
initial_samplesize: 1,583 Japanese ancestry cases, 3,386 Japanese ancestry controls
replication_samplesize: 3,001 Japanese ancestry cases, 5,415 Japanese ancestry controls
study:
Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population.


dbdate: 09/11/2010
author: Zhang H
date: 08/01/2010
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20676096
trait: Hepatocellular carcinoma
initial_samplesize: 348 Chinese ancestry cases, 359 Chinese ancestry controls
replication_samplesize: 2,121 Chinese ancestry cases, 1,748 Chinese ancestry controls
study:
Genome-wide association study identifies 1p36.22 as a new susceptibility locus for hepatocellular carcinoma in chronic hepatitis B virus carriers.


dbdate: 09/14/2010
author: Reed DR
date: 07/31/2010
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20675712
trait: Bitter taste response
initial_samplesize: 1,457 European ancestry individuals
replication_samplesize: 73 European ancestry individuals
study:
The perception of quinine taste intensity is associated with common genetic variants in a bitter receptor cluster on chromosome 12.


dbdate: 09/11/2010
author: Gudbjartsson DF
date: 07/29/2010
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20686651
trait: Chronic kidney disease and serum creatinine levels
initial_samplesize: 1,689 European ancestry cases, 37,076 European ancestry controls
replication_samplesize: 1,972 European ancestry cases, 6,125 European ancestry controls
study:
Association of variants at UMOD with chronic kidney disease and kidney stones-role of age and comorbid diseases.


dbdate: 09/10/2010
author: Kim HN
date: 07/29/2010
journal: J Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20668459
trait: Height
initial_samplesize: 518 individuals from 165 Vietnamese-Korean families
study:
Genetic variants that affect length/height in infancy/early childhood in Vietnamese-Korean families.


dbdate: 09/10/2010
author: Rietschel M
date: 07/29/2010
journal: Biol Psychiatry
link: http://www.ncbi.nlm.nih.gov/pubmed/20673876
trait: Major depressive disorder
initial_samplesize: 597 European ancestry cases, 1,295 European ancestry controls
replication_samplesize: 409 European ancestry cases, 541 European ancestry controls
study:
Genome-wide association-, replication-, and neuroimaging study implicates HOMER1 in the etiology of major depression.


dbdate: 09/10/2010
author: Genovese G
date: 07/28/2010
journal: Kidney Int
link: http://www.ncbi.nlm.nih.gov/pubmed/20668430
trait: Glomerulosclerosis
replication_samplesize: 299 European ancestry cases
study:
A risk allele for focal segmental glomerulosclerosis in African Americans is located within a region containing APOL1 and MYH9.

initial_samplesize:
56 African American cases, 61 European ancestry cases, 1,759 African American controls, 1,531 European ancestry controls


dbdate: 09/07/2010
author: Clancy RM
date: 07/26/2010
journal: Arthritis Rheum
link: http://www.ncbi.nlm.nih.gov/pubmed/20662065
trait: Neonatal lupus
initial_samplesize: 116 European ancestry cases, 3,351 European ancestry controls
study:
Identification of candidate loci at 6p21 and 21q22 in a genome-wide association study of cardiac manifestations of neonatal lupus.


dbdate: 09/10/2010
author: Johansen CT
date: 07/25/2010
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20657596
trait: Hypertriglyceridemia
initial_samplesize: 463 European ancestry cases, 1,197 European ancestry controls
study:
Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia.


dbdate: 09/07/2010
author: Kapur K
date: 07/22/2010
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20661308
trait: Calcium levels
initial_samplesize: 8,918 European ancestry individuals, 3,947 Indian Asians ancestry individuals
replication_samplesize: 4,126 European ancestry individuals
study:
Genome-wide meta-analysis for serum calcium identifies significantly associated SNPs near the calcium-sensing receptor (CASR) gene.


dbdate: 09/01/2010
author: Ochi H
date: 07/13/2010
journal: Gastroenterology
link: http://www.ncbi.nlm.nih.gov/pubmed/20637204
trait: Ribavirin-induced anemia
initial_samplesize: 453 Japanese ancestry individuals
replication_samplesize: 470 Japanese ancestry individuals
study:
ITPA polymorphism affects ribavirin-induced anemia and outcomes of therapy--a genome-wide study of Japanese HCV virus patients.


dbdate: 09/01/2010
author: Gretarsdottir S
date: 07/11/2010
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20622881
trait: Abdominal aortic aneurysm
initial_samplesize: 1,292 European ancestry cases, 30,503 European ancestry controls
replication_samplesize: 3,267 European ancestry cases, 7,451 European ancestry controls
study:
Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm.


dbdate: 08/30/2010
author: Mizuki N
date: 07/11/2010
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20622879
trait: Behcet's disease
initial_samplesize: 611 Japanese ancestry cases, 737 Japanese ancestry controls
study:
Genome-wide association studies identify IL23R-IL12RB2 and IL10 as Beh&#x000e7;et's disease susceptibility loci.

replication_samplesize:
119 Korean ancestry cases, 140 Korean ancestry controls, 1,215 Turkish cases, 1,279 Turkish controls


dbdate: 08/18/2010
author: Remmers EF
date: 07/11/2010
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20622878
trait: Behcet's disease
initial_samplesize: 1,215 Turkish ancestry cases, 1,278 Turkish ancestry controls
study:
Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Beh&#x000e7;et's disease.

replication_samplesize:
Up to 111 Turkish ancestry cases, 225 Turkish ancestry controls, 189 Middle Eastern Arab ancestry cases, 163 Middle Eastern Arab ancestry controls, 227 European ancestry cases, 203 European ancestry controls, 688 East Asian ancestry cases, 791 East Asian ancestry controls


dbdate: 08/11/2010
author: Uno S
date: 07/04/2010
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20601957
trait: Endometriosis
initial_samplesize: 1,423 Japanese ancestry cases, 1,318 Japanese ancestry controls
replication_samplesize: 484 Japanese ancestry cases, 3,974 Japanese ancestry controls
study:
A genome-wide association study identifies genetic variants in the CDKN2BAS locus associated with endometriosis in Japanese.


dbdate: 08/17/2010
author: Koriyama H
date: 07/02/2010
journal: J Atheroscler Thromb
link: http://www.ncbi.nlm.nih.gov/pubmed/20610895
trait: Peripheral artery disease
initial_samplesize: 195 Japanese ancestry cases, 1,358 Japanese ancestry controls
replication_samplesize: 699 Japanese ancestry cases, 1,540 Japanese ancestry controls
study:
Identification of evidence suggestive of an association with peripheral arterial disease at the OSBPL10 locus by genome-wide investigation in the Japanese population.


dbdate: 11/09/2013
author: Chen SH
date: 06/30/2010
journal: Clin Pharmacol Ther
link: http://www.ncbi.nlm.nih.gov/pubmed/20592726
study: Genetic variations in GRIA1 on chromosome 5q33 related to asparaginase hypersensitivity.
trait: Asparaginase hypersensitivity in acute lymphoblastic leukemia
initial_samplesize:
211 European ancestry child cases, 40 Black child cases, 46 Hispanic child cases, 4 Asian child cases, 21 Other ancestry child cases

replication_samplesize:
99 European ancestry child cases, 33 Black child cases, 24 Hispanic child cases, 2 Asian child cases, 5 Other ancestry child cases


dbdate: 07/13/2010
author: Dick DM
date: 06/27/2010
journal: Mol Psychiatry
link: http://www.ncbi.nlm.nih.gov/pubmed/20585324
study: Genome-wide association study of conduct disorder symptomatology.
trait: Conduct disorder
initial_samplesize:
872 European, African American and other ancestry substance dependence cases; 3,091 European, African American and other ancestry controls


dbdate: 07/12/2010
author: Long J
date: 06/24/2010
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20585626
trait: Breast cancer
initial_samplesize: 2,073 Chinese ancestry cases, 2,084 Chinese ancestry controls
study:
Identification of a functional genetic variant at 16q12.1 for breast cancer risk: results from the Asia Breast Cancer Consortium.

replication_samplesize:
15,159 East Asian ancestry cases, 12,993 East Asian ancestry controls, 2,797 European ancestry cases, 2,662 European ancestry controls


dbdate: 07/04/2010
author: Hsu YH
date: 06/10/2010
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20548944
trait: Osteoporosis-related phenotypes
initial_samplesize: 2,038 European ancestry women, 1,531 European ancestry men
replication_samplesize: 5,595 European ancestry women, 2,126 European ancestry men
study:
An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits.


dbdate: 07/01/2010
author: Bostrom MA
date: 06/08/2010
journal: Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20532800
trait: End-stage renal disease (non-diabetic)
initial_samplesize: 464 African American cases, 478 African American controls
replication_samplesize: 336 African American cases, 363 African American controls
study:
Candidate genes for non-diabetic ESRD in African Americans: a genome-wide association study using pooled DNA.


dbdate: 06/22/2010
author: Johnson AD
date: 06/06/2010
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20526338
trait: Platelet aggregation
initial_samplesize: Up to 3,991 European ancestry individuals
replication_samplesize: Up to 840 African American individuals
study:
Genome-wide meta-analyses identifies seven loci associated with platelet aggregation in response to agonists.


dbdate: 06/14/2010
author: Bei JX
date: 05/30/2010
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20512145
trait: Nasopharyngeal carcinoma
initial_samplesize: 1,583 Chinese ancestry cases, 1,894 Chinese ancestry controls
replication_samplesize: 3,507 Chinese ancestry cases, 3,063 Chinese ancestry controls, 284 Chinese ancestry trios
study:
A genome-wide association study of nasopharyngeal carcinoma identifies three new susceptibility loci.


dbdate: 06/14/2010
author: Lu Y
date: 05/13/2010
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20485516
trait: Central corneal thickness
study:
Common genetic variants near the Brittle Cornea Syndrome locus ZNF469 influence the blinding disease risk factor central corneal thickness.

initial_samplesize:
3,473 European ancestry twins in 1,905 families, 301 European ancestry thin CCT cases, 301 European ancestry thick CCT controls


dbdate: 06/02/2010
author: Smith NL
date: 05/05/2010
journal: Circ Cardiovasc Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20445134
trait: Heart failure
initial_samplesize: 20,926 European ancestry individuals, 2,895 African ancestry individuals
study:
Association of genome-wide variation with the risk of incident heart failure in adults of European and African ancestry: a prospective meta-analysis from the cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium.


dbdate: 05/31/2010
author: Albagha OM
date: 05/02/2010
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20436471
trait: Paget's disease
initial_samplesize: 692 European ancestry cases, 1,001 European ancestry controls
replication_samplesize: 256 European ancestry cases, 488 European ancestry controls
study:
Genome-wide association study identifies variants at CSF1, OPTN and TNFRSF11A as genetic risk factors for Paget's disease of bone.


dbdate: 05/26/2010
author: Beaty TH
date: 05/02/2010
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20436469
trait: Cleft lip
initial_samplesize: 825 European ancestry trios, 1,038 Asian ancestry trios
study:
A genome-wide association study of cleft lip with and without cleft palate identifies risk variants near MAFB and ABCA4.

replication_samplesize:
2,194 Asian ancestry family members, 322 South Asian ancestry family members, 3,830 European ancestry family members, 1,769 South and Central American ancestry family members


dbdate: 06/26/2014
author: Scherag A
date: 04/22/2010
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20421936
trait: Obesity (early onset extreme)
initial_samplesize: 1,138 European ancestry cases, 1,120 European ancestry normal or lean controls
study:
Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups.

replication_samplesize:
1,181 European ancestry cases, 1,960 European ancestry normal or lean controls, 981 European ancestry cases  and 1,430 European ancestry controls from 715 families


dbdate: 05/18/2010
author: Jin Y
date: 04/21/2010
journal: N Engl J Med
link: http://www.ncbi.nlm.nih.gov/pubmed/20410501
study: Variant of TYR and autoimmunity susceptibility loci in generalized vitiligo.
trait: Vitiligo
initial_samplesize: 1,392 European ancestry cases, 2,629 European ancestry controls
replication_samplesize:
647 European ancestry cases, 1,056 European ancestry controls, 183 European ancestry trios, 1,383 European ancestry individuals from 332 families


dbdate: 05/23/2010
author: Morrison AC
date: 04/17/2010
journal: Circ Cardiovasc Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20400778
trait: Mortality in heart failure
study:
Genomic variation associated with mortality among adults of European and African ancestry with heart failure: the cohorts for heart and aging research in genomic epidemiology consortium.

initial_samplesize:
1,645 European ancestry cases, 881 European ancestry controls, 281 African ancestry cases, 185 African ancestry controls


dbdate: 07/01/2014
author: Chen W
date: 04/12/2010
journal: Proc Natl Acad Sci U S A
link: http://www.ncbi.nlm.nih.gov/pubmed/20385819
trait: Age-related macular degeneration
initial_samplesize: 2,157 European ancestry cases, 1,150 European ancestry controls
study:
Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration.

replication_samplesize:
7,892 European ancestry cases, 678 Japanese cases, 5,998 European ancestry controls, 336 Japanese controls


dbdate: 05/06/2010
author: Neale BM
date: 04/12/2010
journal: Proc Natl Acad Sci U S A
link: http://www.ncbi.nlm.nih.gov/pubmed/20385826
trait: Age-related macular degeneration
initial_samplesize: 979 cases, 1,709 controls
replication_samplesize: 868 European ancestry cases, 410 European ancestry controls, 4,921 cases, 3,824 controls
study:
Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC).


dbdate: 04/27/2010
author: Freathy RM
date: 04/06/2010
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20372150
study: Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight.
trait: Birth weight
initial_samplesize: 10,623 European ancestry individuals
replication_samplesize:
27,591 European ancestry individuals, 1,415 Filipino ancestry individuals, 746 North African ancestry individuals, 333 Turkish ancestry individuals


dbdate: 05/03/2010
author: Meguro A
date: 04/02/2010
journal: Ophthalmology
link: http://www.ncbi.nlm.nih.gov/pubmed/20363506
trait: Glaucoma
initial_samplesize: 305 Japanese ancestry cases, 355 Japanese ancestry controls
study:
Genome-wide association study of normal tension glaucoma: common variants in SRBD1 and ELOVL5 contribute to disease susceptibility.


dbdate: 04/15/2010
author: Liu Y
date: 03/30/2010
journal: Mol Psychiatry
link: http://www.ncbi.nlm.nih.gov/pubmed/20351715
study: Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.
trait: Bipolar disorder and major depressive disorder (combined)
initial_samplesize:
4,387 European ancestry bipolar cases, 1,695 European ancestry major depressive disorder cases, 7,970 European ancestry controls


dbdate: 11/03/2013
author: Takahashi M
date: 03/29/2010
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20350937
trait: Thyroid cancer (Papillary, radiation-related)
initial_samplesize: 401 European ancestry cases, 620 European ancestry controls,
replication_samplesize: 259 Other ancestry cases, 648 Other ancestry controls
study:
The FOXE1 locus is a major genetic determinant for radiation-related thyroid carcinoma in Chernobyl.


dbdate: 10/18/2013
author: Kim S
date: 03/23/2010
journal: Mol Psychiatry
link: http://www.ncbi.nlm.nih.gov/pubmed/20308991
trait: Brain cytoarchitecture
study:
Integrative genome-wide association analysis of cytoarchitectural abnormalities in the prefrontal cortex of psychiatric disorders.

initial_samplesize:
14 European ancestry bipolar cases, 15 European ancestry depression cases, 13 European ancestry schizophrenia cases, 14 European ancestry controls


dbdate: 03/29/2010
author: Li Y
date: 03/19/2010
journal: Lancet Oncol
link: http://www.ncbi.nlm.nih.gov/pubmed/20304703
study: Genetic variants and risk of lung cancer in never smokers: a genome-wide association study.
trait: Lung cancer
initial_samplesize:
364 European ancestry cases, 364 European ancestry controls, 13 Other ancestry cases, 13 Other ancestry controls

replication_samplesize:
446 European ancestry cases, 853 European ancestry controls, 65 Other ancestry cases, 154 Other ancestry controls


dbdate: 04/12/2010
author: Houlihan LM
date: 03/18/2010
journal: Am J Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20303064
trait: Activated partial thromboplastin time
initial_samplesize: 1,431 European ancestry individuals
study:
Common variants of large effect in F12, KNG1, and HRG are associated with activated partial thromboplastin time.


dbdate: 04/02/2010
author: Medland SE
date: 03/18/2010
journal: Am J Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20303062
trait: Digit length ratio
initial_samplesize: 2,889 European ancestry children and adolescents
replication_samplesize: 3,659 European ancestry children
study:
A variant in LIN28B is associated with 2D:4D finger-length ratio, a putative retrospective biomarker of prenatal testosterone exposure.


dbdate: 04/02/2010
author: Nakajima M
date: 03/18/2010
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/20305777
trait: Knee osteoarthritis
initial_samplesize: 899 Japanese ancestry cases, 3,396 Japanese ancestry controls
study:
New sequence variants in HLA class II/III region associated with susceptibility to knee osteoarthritis identified by genome-wide association study.

replication_samplesize:
167 Japanese ancestry cases, 347 Japanese ancestry controls, 813 European ancestry  cases, 1071 European ancestry controls,


dbdate: 04/12/2010
author: Newman AB
date: 03/18/2010
journal: J Gerontol A Biol Sci Med Sci
link: http://www.ncbi.nlm.nih.gov/pubmed/20304771
trait: Longevity
initial_samplesize: 1,836 long-lived European ancestry individuals, 1,955 European ancestry controls
replication_samplesize: 2,594 long-lived European ancestry individuals, 3,431 European ancestry controls
study:
A meta-analysis of four genome-wide association studies of survival to age 90 years or older: the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium.


dbdate: 03/26/2010
author: Smith NL
date: 03/15/2010
journal: Circulation
link: http://www.ncbi.nlm.nih.gov/pubmed/20231535
trait: Coagulation factor levels
initial_samplesize: Up to 23,608 European ancestry individuals
replication_samplesize: Up to 7,604 European ancestry individuals
study:
Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium.


dbdate: 03/24/2010
author: Franke A
date: 03/14/2010
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20228798
trait: Ulcerative colitis
initial_samplesize: 1,043 European ancestry cases, 1,703 European ancestry controls
replication_samplesize: 2,539 European ancestry cases, 5,428 European ancestry controls
study:
Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 (IL17REL).


dbdate: 03/30/2010
author: Buil A
date: 03/08/2010
journal: Blood
link: http://www.ncbi.nlm.nih.gov/pubmed/20212171
trait: C4b binding protein levels
initial_samplesize: 352 related European ancestry individuals
study:
C4BPB/C4BPA is a new susceptibility locus for venous thrombosis with unknown protein S-independent mechanism: results from genome-wide association and gene expression analyses followed by case-control studies.


dbdate: 09/27/2013
author: Stein JL
date: 03/01/2010
journal: Neuroimage
link: http://www.ncbi.nlm.nih.gov/pubmed/20197096
trait: Brain structure (hippocampal volume)
study:
Genome-wide analysis reveals novel genes influencing temporal lobe structure with relevance to neurodegeneration in Alzheimer's disease.

initial_samplesize:
162 European ancestry Alzheimer's disease cases, 343 European ancestry amnestic mild cognitive impairment cases, 193 European ancestry healthy elderly controls


dbdate: 03/25/2010
author: Okada Y
date: 02/26/2010
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20189936
trait: Height
initial_samplesize: 19,633 Japanese ancestry individuals
study:
A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.


dbdate: 03/25/2010
author: Pillas D
date: 02/26/2010
journal: PLoS Genet
trait: Primary tooth development (number of teeth)
initial_samplesize: 5,752 European ancestry related individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/20195514?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=14

study:
Genome-wide association study reveals multiple loci associated with primary tooth development during infancy.


dbdate: 03/25/2010
author: Athanasiu L
date: 02/23/2010
journal: J Psychiatr Res
link: http://www.ncbi.nlm.nih.gov/pubmed/20185149
trait: Schizophrenia
initial_samplesize: 201 European ancestry cases, 305 European ancestry controls
replication_samplesize: 2,663 European ancestry cases, 13,780 European ancestry controls
study:
Gene variants associated with schizophrenia in a Norwegian genome-wide study are replicated in a large European cohort.


dbdate: 03/17/2010
author: Qi L
date: 02/22/2010
journal: Hum Mol Genet
trait: E-selectin levels
initial_samplesize: 501 European ancestry type 2 diabetes women cases, 504 European ancestry women controls
replication_samplesize: 518 European ancestry women
link:
http://www.ncbi.nlm.nih.gov/pubmed/20147318?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=1

study:
Genetic variants in ABO blood group region, plasma soluble E-selectin levels and risk of type 2 diabetes.


dbdate: 03/17/2010
author: Sun Q
date: 02/22/2010
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20167575
trait: Soluble leptin receptor levels
initial_samplesize: 684 European ancestry type 2 diabetes women cases, 820 European ancestry women controls
replication_samplesize: 875 European ancestry males
study:
Genome-wide association study identifies polymorphisms in LEPR as determinants of plasma soluble leptin receptor levels.


dbdate: 03/17/2010
author: Cho MH
date: 02/21/2010
journal: Nat Genet
study: Variants in FAM13A are associated with chronic obstructive pulmonary disease.
trait: Chronic obstructive pulmonary disease
initial_samplesize: 2,940 European ancestry cases, 1,380 European ancestry controls
replication_samplesize: 502 European ancestry cases, 504 European ancestry controls, 1,110 cases, 2,698 controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/20173748?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=1


dbdate: 03/15/2010
author: Ellinor PT
date: 02/21/2010
journal: Nat Genet
study: Common variants in KCNN3 are associated with lone atrial fibrillation.
trait: Atrial fibrillation
initial_samplesize: 1,335 European ancestry cases, 12,844 European ancestry controls
replication_samplesize: 1,164 European ancestry cases, 3,607 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/20173747?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=1


dbdate: 03/17/2010
author: Tsai FJ
date: 02/19/2010
journal: PLoS Genet
trait: Type 2 diabetes
initial_samplesize: 995 Han Chinese ancestry cases, 894 Han Chinese ancestry controls
replication_samplesize: 1,803 Han Chinese ancestry cases, 1,473 Han Chinese ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/20174558?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=1

study:
A genome-wide association study identifies susceptibility variants for type 2 diabetes in Han Chinese.


dbdate: 03/15/2010
author: Barbalic M
date: 02/18/2010
journal: Hum Mol Genet
study: Large-scale genomic studies reveal central role of ABO in sP-selectin and sICAM-1 levels.
trait: Soluble levels of adhesion molecules
initial_samplesize: Up to 9,813 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/20167578?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=1


dbdate: 03/12/2010
author: Okada Y
date: 02/18/2010
journal: Hum Mol Genet
study: Common variations in PSMD3-CSF3 and PLCB4 are associated with neutrophil count.
trait: Neutrophil count
initial_samplesize: 5,771 Japanese ancestry individuals
replication_samplesize: 1,894 Japanese ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/20172861?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=1


dbdate: 03/23/2010
author: Stein JL
date: 02/17/2010
journal: Neuroimage
study: Voxelwise genome-wide association study (vGWAS).
trait: Brain structure
initial_samplesize: 740 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/20171287?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=1


dbdate: 09/25/2013
author: Herbeck JT
date: 02/15/2010
journal: J Infect Dis
link: http://www.ncbi.nlm.nih.gov/pubmed/20064070
trait: HIV-1 progression
replication_samplesize: 590 European ancestry seroconverter males
study:
Multistage genomewide association study identifies a locus at 1q41 associated with rate of HIV-1 disease progression to clinical AIDS.

initial_samplesize:
51 European ancestry rapid progressor males, 57 European ancestry moderate progressor males, 48 European ancestry long-term progressor males


dbdate: 03/09/2010
author: Lange LA
date: 02/13/2010
journal: Hum Mol Genet
trait: Homocysteine levels
initial_samplesize: 1,786 Filipino ancestry women
replication_samplesize: 1,679 Filipino ancestry offspring
link:
http://www.ncbi.nlm.nih.gov/pubmed/20154341?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=3

study:
Genome-wide association study of homocysteine levels in Filipinos provides evidence for CPS1 in women and a stronger MTHFR effect in young adults.


dbdate: 03/07/2010
author: Jakkula E
date: 02/12/2010
journal: Am J Hum Genet
trait: Multiple sclerosis
initial_samplesize: 68 Finland founder cases, 136 Finland founder controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/20159113?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=1

study:
Genome-wide association study in a high-risk isolate for multiple sclerosis reveals associated variants in STAT3 gene.

replication_samplesize:
83 Finland founder cases, 365 Finland founder controls 3,285 European ancestry cases, 6,379 European ancestry controls, 342 Other ancestry cases, 1,679 Other ancestry controls, 860 cases, 1,720 controls


dbdate: 03/06/2010
author: Yang W
date: 02/12/2010
journal: PLoS Genet
trait: Systemic lupus erythematosus
initial_samplesize: 314 Chinese ancestry cases, 1,484 Chinese ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/20169177?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=2

study:
Genome-wide association study in Asian populations identifies variants in ETS1 and WDFY4 associated with systemic lupus erythematosus.

replication_samplesize:
2,630 Chinese ancestry cases, 2,155 Chinese ancestry controls, 314 Thai ancestry cases, 519 Thai ancestry controls


dbdate: 03/06/2010
author: He M
date: 02/11/2010
journal: Arterioscler Thromb Vasc Biol
trait: Interleukin-18 levels
initial_samplesize: 1,523 European ancestry women
replication_samplesize: 435 European ancestry women
link:
http://www.ncbi.nlm.nih.gov/pubmed/20150558?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=6

study:
Genome-wide association study identifies variants at the IL18-BCO2 locus associated with interleukin-18 levels.


dbdate: 10/18/2013
author: Xing C
date: 02/11/2010
journal: Am J Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20152958
trait: Fasting plasma glucose
initial_samplesize: 2,029 African American individuals, 7,428 European ancestry individuals
replication_samplesize: 1,571 African American individuals, 3,825 European ancestry individuals
study:
A weighted false discovery rate control procedure reveals alleles at FOXA2 that influence fasting glucose levels.


dbdate: 03/06/2010
author: Codd V
date: 02/07/2010
journal: Nat Genet
study: Common variants near TERC are associated with mean telomere length.
trait: Telomere length
initial_samplesize: 2,917 European ancestry individuals
replication_samplesize: 9,492 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/20139977?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=1


dbdate: 11/13/2012
author: Cirulli ET
date: 02/03/2010
journal: Eur J Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20125193
study: Common genetic variation and performance on standardized cognitive tests.
trait: Cognitive performance
initial_samplesize:
Up to 813 European ancestry individuals, up to 167 East Asian ancestry individuals, up to 7 Hispanic/Latin American amncestry individuals, up to 74 South Asian ancestry individuals


dbdate: 03/02/2010
author: Shi J
date: 02/02/2010
journal: Mol Psychiatry
study: Genome-wide association study of recurrent early-onset major depressive disorder.
trait: Major depressive disorder
initial_samplesize: 1,020 European ancestry cases, 1,636 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/20125088?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=1


dbdate: 03/05/2010
author: Li X
date: 02/01/2010
journal: J Allergy Clin Immunol
study: Genome-wide association study of asthma identifies RAD50-IL13 and HLA-DR/DQ regions.
trait: Asthma
initial_samplesize: 607 European ancestry cases, 3,294 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/20159242?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=1


dbdate: 02/28/2010
author: Petersen GM
date: 01/24/2010
journal: Nat Genet
trait: Pancreatic cancer
link:
http://www.ncbi.nlm.nih.gov/pubmed/20101243?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=11

study:
A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33.

initial_samplesize:
3,851 cases of European, Chinese or other ancestries, 3,934 controls of European, Chinese or other ancestries


dbdate: 02/12/2010
author: Shen L
date: 01/22/2010
journal: Neuroimage
trait: Brain imaging
link:
http://www.ncbi.nlm.nih.gov/pubmed/20100581?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=1

study:
Whole genome association study of brain-wide imaging phenotypes for identifying quantitative trait loci in MCI and AD: A study of the ADNI cohort.

initial_samplesize:
175 European ancestry Alzheimer cases, 354 European ancestry amnestic mild cognitive impairment cases, 204 European ancestry controls


dbdate: 02/10/2010
author: Kung AW
date: 01/20/2010
journal: Am J Hum Genet
trait: Bone mineral density
initial_samplesize: 785 Han Chinese ancestry extreme high and low BMD women
link:
http://www.ncbi.nlm.nih.gov/pubmed/20096396?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=4

study:
Association of JAG1 with bone mineral density and osteoporotic fractures: a genome-wide association study and follow-up replication studies.

replication_samplesize:
264 Han Chinese ancestry High BMD individuals, 456 Han Chinese ancestry Low BMD individuals, 3,465 Han Chinese ancestry individuals, 13,913 European ancestry individuals


dbdate: 02/28/2010
author: Dupuis J
date: 01/17/2010
journal: Nat Genet
trait: Fasting glucose-related traits
initial_samplesize: up to 46,186 European descent individuals
replication_samplesize: up to 76,558 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/20081858?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=1

study:
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.


dbdate: 02/08/2010
author: McMahon FJ
date: 01/17/2010
journal: Nat Genet
trait: Major mood disorders
initial_samplesize: 6,686 European ancestry cases, 9,068 European ancestry controls
replication_samplesize: 1,930 European ancestry cases, 2,747 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/20081856?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=2

study:
Meta-analysis of genome-wide association data identifies a risk locus for major mood disorders on 3p21.1.


dbdate: 02/08/2010
author: Saxena R
date: 01/17/2010
journal: Nat Genet
trait: Two-hour glucose challenge
initial_samplesize: 15,234 individuals
replication_samplesize: up to 30,620 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/20081857?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=3

study:
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.


dbdate: 02/05/2010
author: Edwards TL
date: 01/13/2010
journal: Ann Hum Genet
trait: Parkinson's disease
initial_samplesize: 1,752 European ancestry cases, 1,745 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/20070850?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=3

study:
Genome-wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease.


dbdate: 02/04/2010
author: Van Laer L
date: 01/13/2010
journal: Eur J Hum Genet
study: A genome-wide association study for age-related hearing impairment in the Saami.
trait: Hearing impairment
initial_samplesize: 347 Finnish Saami individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/20068591?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=2


dbdate: 02/02/2010
author: Chung CM
date: 01/12/2010
journal: Pharmacogenomics J
trait: Angiotensin-converting enzyme activity
initial_samplesize: 400 Han Chinese ancestry hypertensive cases
replication_samplesize: 623 Han Chinese ancestry hypertensive cases
link:
http://www.ncbi.nlm.nih.gov/pubmed/20066004?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=4

study:
A genome-wide association study identifies new loci for ACE activity: potential implications for response to ACE inhibitor.


dbdate: 01/29/2010
author: Chambers JC
date: 01/10/2010
journal: Nat Genet
study: Genetic variation in SCN10A influences cardiac conduction.
trait: Electrocardiographic traits
initial_samplesize: 6,543 Indian Asian ancestry individuals
replication_samplesize: 6,243 Indian Asian ancestry individuals, 5,370 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/20062061?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=2


dbdate: 02/02/2010
author: Holm H
date: 01/10/2010
journal: Nat Genet
study: Several common variants modulate heart rate, PR interval and QRS duration.
trait: Electrocardiographic traits
initial_samplesize: Up to 12,670 European ancestry individuals
replication_samplesize: Up to 10,352 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/20062063?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=2


dbdate: 02/04/2010
author: Pfeufer A
date: 01/10/2010
journal: Nat Genet
study: Genome-wide association study of PR interval.
trait: PR interval
initial_samplesize: 28,517 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/20062060?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=1


dbdate: 02/02/2010
author: Reveille JD
date: 01/10/2010
journal: Nat Genet
study: Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci.
trait: Ankylosing spondylitis
initial_samplesize: 2,053 European ancestry cases, 5,140 European ancestry controls
replication_samplesize: 898 European ancestry cases, 1,518 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/20062062?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=1


dbdate: 01/28/2010
author: Guo Y
date: 01/08/2010
journal: PLoS Genet
study: Genome-wide association study identifies ALDH7A1 as a novel susceptibility gene for osteoporosis.
trait: Osteoporosis
initial_samplesize: 350 Han Chinese ancestry cases, 350 Han Chinese ancestry controls
replication_samplesize: 390 Han Chinese ancestry cases, 516 Han Chinsese ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/20072603?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=2


dbdate: 01/21/2010
author: Igl W
date: 01/08/2010
journal: PLoS Genet
trait: Cholesterol
initial_samplesize: 656 European ancestry individuals
replication_samplesize: Up to 3,282 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/20066028?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=1

study:
Modeling of environmental effects in genome-wide association studies identifies SLC2A2 and HP as novel loci influencing serum cholesterol levels.


dbdate: 02/28/2010
author: Kerkhof HJ
date: 01/07/2010
journal: Arthritis Rheum
trait: Osteoarthritis
initial_samplesize: 1,341 European ancestry cases, 3,496 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/20112360?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=1

study:
A genome-wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22.

replication_samplesize:
9,779 European ancestry cases, up to 31,818 European ancestry controls, 1,861 Other ancestry cases, 5,536 Other ancestry controls, 1,957 cases, 1,742 controls


dbdate: 01/21/2010
author: Rauch A
date: 01/07/2010
journal: Gastroenterology
trait: Chronic hepatitis C infection
link:
http://www.ncbi.nlm.nih.gov/pubmed/20060832?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=4

study:
Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: a genome-wide association study.

initial_samplesize:
1,015 European ancestry chronic HCV carriers, 347 European ancestry spontaneously cleared HCV individuals


dbdate: 03/17/2010
author: Liu X
date: 01/01/2010
journal: J Am Acad Child Adolesc Psychiatry
link: http://www.ncbi.nlm.nih.gov/pubmed/20215924
study: A genome-wide association study of amygdala activation in youths with and without bipolar disorder.
trait: Functional MRI
initial_samplesize:
36 European ancestry BD cases, 1 African American BD case, 2 Other ancestry BD cases, 21 European ancestry controls, 5 African American controls, 3 Other ancestry controls


dbdate: 01/19/2010
author: Shrestha S
date: 01/01/2010
journal: AIDS
study: A genome-wide association study of carotid atherosclerosis in HIV-infected men.
trait: Carotid atherosclerosis in HIV infection
initial_samplesize: 177 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/20009918?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=4


dbdate: 08/30/2010
author: Ferreira MA
date: 12/31/2009
journal: Am J Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20045101
trait: CD4:CD8 lymphocyte ratio
initial_samplesize: 2,538 European ancestry twins from 1,089 families
replication_samplesize: 988 individuals from 550 families
study:
Quantitative trait loci for CD4:CD8 lymphocyte ratio are associated with risk of type 1 diabetes and HIV-1 immune control.


dbdate: 01/19/2010
author: Shyn SI
date: 12/29/2009
journal: Mol Psychiatry
trait: Major depressive disorder (broad)
initial_samplesize: 3,957 European ancestry cases, 3,428 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/20038947?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=1

study:
Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies.


dbdate: 01/19/2010
author: Fellay J
date: 12/24/2009
journal: PLoS Genet
study: Common genetic variation and the control of HIV-1 in humans.
trait: HIV-1 control
initial_samplesize: 2,362 European ancestry cases
link:
http://www.ncbi.nlm.nih.gov/pubmed/20041166?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=1


dbdate: 01/13/2010
author: Sleiman PM
date: 12/23/2009
journal: N Engl J Med
study: Variants of DENND1B associated with asthma in children.
trait: Asthma
initial_samplesize: 793 European ancestry cases, 1,988 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/20032318?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=1

replication_samplesize:
917 European ancestry cases, 1,546 European ancestry controls, 1,667 African American cases, 2,045 African American controls


dbdate: 12/28/2009
author: Mangold E
date: 12/20/2009
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20023658
trait: Orofacial clefts
initial_samplesize: 399 European ancestry cases, 1,318 European ancestry controls
replication_samplesize: 655 European ancestry triads
study:
Genome-wide association study identifies two susceptibility loci for nonsyndromic cleft lip with or without cleft palate.


dbdate: 11/09/2013
author: Solovieff N
date: 12/16/2009
journal: Blood
link: http://www.ncbi.nlm.nih.gov/pubmed/20018918
trait: Fetal hemoglobin levels
initial_samplesize: 848 Black cases
replication_samplesize: 305 Black cases, 406 Chinese ancestry cases, 113 Thai ancestry cases
study:
Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5' olfactory receptor gene cluster.


dbdate: 12/28/2009
author: Zhang FR
date: 12/16/2009
journal: N Engl J Med
study: Genomewide association study of leprosy.
trait: Leprosy
initial_samplesize: 706 Han Chinese ancestry cases, 1,225 Han Chinese ancestry controls
replication_samplesize: 3,254 Chinese ancestry cases, 5,955 Chinese ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/20018961?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=1


dbdate: 01/13/2010
author: Hancock DB
date: 12/13/2009
journal: Nat Genet
trait: Pulmonary function
initial_samplesize: 20,890 European ancestry individuals
replication_samplesize: 16,178 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/20010835?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=5

study:
Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function.


dbdate: 12/28/2009
author: Repapi E
date: 12/13/2009
journal: Nat Genet
study: Genome-wide association study identifies five loci associated with lung function.
trait: Pulmonary function
initial_samplesize: 20,288 European ancestry individuals
replication_samplesize: up to 54,276 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/20010834?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=1


dbdate: 12/28/2009
author: Castro-Giner F
date: 12/06/2009
journal: BMC Med Genet
trait: Atopy
replication_samplesize: 429 European ancestry atopy cases, 222 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19961619?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=2

study:
A pooling-based genome-wide analysis identifies new potential candidate genes for atopy in the European Community Respiratory Health Survey (ECRHS).

initial_samplesize:
75 European ancestry atopy and asthma cases, 75 European ancestry atopy only cases, 75 European ancestry controls


dbdate: 12/28/2009
author: Wallace C
date: 12/06/2009
journal: Nat Genet
study: The imprinted DLK1-MEG3 gene region on chromosome 14q32.2 alters susceptibility to type 1 diabetes.
trait: Type 1 diabetes
initial_samplesize: 7,514 European ancestry cases, 9,045 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19966805?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=7

replication_samplesize:
4,840 European ancestry cases, 2,670 European ancestry controls, 5,766 European ancestry familial triads


dbdate: 01/07/2010
author: Richards JB
date: 12/05/2009
journal: PLoS Genet
study: A genome-wide association study reveals variants in ARL15 that influence adiponectin levels.
trait: Adiponectin levels
initial_samplesize: 8,531 European ancestry individuals
replication_samplesize: 6,202 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/20011104?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=2


dbdate: 01/13/2010
author: Heid IM
date: 12/02/2009
journal: Atherosclerosis
trait: Adiponectin levels
initial_samplesize: 4,659 European ancestry individuals
replication_samplesize: 13,795 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/20018283?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=1

study:
Clear detection of ADIPOQ locus as the major gene for plasma adiponectin: results of genome-wide association analyses including 4659 European individuals.


dbdate: 09/24/2013
author: Chasman DI
date: 11/20/2009
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/19936222
trait: Lipid metabolism phenotypes
initial_samplesize: Up to 17,296 European ancestry women
study:
Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.

replication_samplesize:
Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls


dbdate: 12/28/2009
author: Nuinoon M
date: 11/19/2009
journal: Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20183929
trait: Beta thalassemia/hemoglobin E disease
initial_samplesize: 235 mild Thai-Chinese ancesry cases, 383 severe Thai-Chinese ancestry cases
replication_samplesize: 52 mild Indonesian ancestry cases, 122 severe Indonesian ancestry cases
study:
A genome-wide association identified the common genetic variants influence disease severity in beta0-thalassemia/hemoglobin E.


dbdate: 12/14/2009
author: Asano K
date: 11/15/2009
journal: Nat Genet
trait: Ulcerative colitis
initial_samplesize: 376 Japanese ancestry cases, 934 Japanese ancestry controls
replication_samplesize: 376 Japanese ancestry cases, 1,097 Japanese ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19915573?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=3

study:
A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population.


dbdate: 12/11/2009
author: Barrett JC
date: 11/15/2009
journal: Nat Genet
trait: Ulcerative colitis
initial_samplesize: 2,361 European ancestry cases, 5,417 European ancestry controls
replication_samplesize: 2,321 European ancestry cases, 4,818 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19915572?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=1

study:
Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region.


dbdate: 12/10/2009
author: Imielinski M
date: 11/15/2009
journal: Nat Genet
study: Common variants at five new loci associated with early-onset inflammatory bowel disease.
trait: Inflammatory bowel disease (early onset)
initial_samplesize: 2,413 European ancestry cases, 6,158 European ancestry controls
replication_samplesize: 1,013 European ancestry cases, 5,805 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19915574?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=1


dbdate: 12/10/2009
author: Satake W
date: 11/15/2009
journal: Nat Genet
trait: Parkinson's disease
initial_samplesize: 988 Japanese ancestry cases, 2,521 Japanese ancestry controls
replication_samplesize: 933 Japanese ancestry cases, 15,753 Japanese ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19915576?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=1

study:
Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease.


dbdate: 12/10/2009
author: Simon-Sanchez J
date: 11/15/2009
journal: Nat Genet
study: Genome-wide association study reveals genetic risk underlying Parkinson's disease.
trait: Parkinson's disease
initial_samplesize: 1,713 European ancestry cases, 3,978 European ancestry controls
replication_samplesize: 3,361 European ancestry cases, 4,573 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19915575?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=1


dbdate: 09/24/2013
author: Trevino LR
date: 11/09/2009
journal: J Clin Oncol
link: http://www.ncbi.nlm.nih.gov/pubmed/19901119
trait: Methotrexate phramacokinetics (acute lymphoblastic leukemia)
study:
Germline genetic variation in an organic anion transporter polypeptide associated with methotrexate pharmacokinetics and clinical effects.

initial_samplesize:
315 European ancestry cases; 73 African American cases; 41 Other ancestry cases, 5 Asian unspecified cases; 206 cases


dbdate: 12/04/2009
author: Schaefer AS
date: 11/06/2009
journal: Hum Mol Genet
study: A genome-wide association study identifies GLT6D1 as a susceptibility locus for periodontitis.
trait: Periodontitis
initial_samplesize: 283 European ancestry cases, 972 European ancestry controls
replication_samplesize: 155 European ancestry cases, 341 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19897590?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=3


dbdate: 12/03/2009
author: Birlea SA
date: 11/05/2009
journal: J Invest Dermatol
trait: Vitiligo
initial_samplesize: 32 Romanian founder cases, 44 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19890347?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=1

study:
Genome-wide association study of generalized vitiligo in an isolated European founder population identifies SMOC2, in close proximity to IDDM8.


dbdate: 12/04/2009
author: Medland SE
date: 11/04/2009
journal: Am J Hum Genet
study: Common variants in the trichohyalin gene are associated with straight hair in Europeans.
trait: Hair morphology
initial_samplesize: 4,845 European ancestry individuals from 2,892 families, 16,140 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/19896111?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=2


dbdate: 12/01/2009
author: Tanaka T
date: 10/30/2009
journal: Blood
study: A genome-wide association analysis of serum iron concentrations.
trait: Iron levels
initial_samplesize: 1,919 European ancestry individuals
replication_samplesize: 569 females
link:
http://www.ncbi.nlm.nih.gov/pubmed/19880490?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=1


dbdate: 12/01/2009
author: Guo Y
date: 10/29/2009
journal: J Bone Miner Res
trait: Bone mineral density
initial_samplesize: 983 European ancestry individuals
replication_samplesize: 2,557 European ancestry individuals from 750 families
link:
http://www.ncbi.nlm.nih.gov/pubmed/19874204?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=1

study:
IL21R and PTH may underlie variation of femoral neck bone mineral density as revealed by a genome-wide association study.


dbdate: 11/30/2009
author: Aberg K
date: 10/27/2009
journal: Biol Psychiatry
study: Genomewide association study of movement-related adverse antipsychotic effects.
trait: Response to antipsychotic therapy (extrapyramidal side effects)
link:
http://www.ncbi.nlm.nih.gov/pubmed/19875103?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=2

initial_samplesize:
421 European ancestry schizophrenia cases, 214 African American schizophrenia cases, 103 Other ancestry schizophrenia cases


dbdate: 11/18/2009
author: Johansson A
date: 10/22/2009
journal: Obesity (Silver Spring)
trait: Body mass index
link:
http://www.ncbi.nlm.nih.gov/pubmed/19851299?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=4

study:
Linkage and genome-wide association analysis of obesity-related phenotypes: association of weight with the MGAT1 gene.

initial_samplesize:
1,079 South Tyrolian individuals, 790 Dutch founder individuals, 2,060 European ancestry individuals


dbdate: 11/25/2009
author: Garriock HA
date: 10/19/2009
journal: Biol Psychiatry
study: A genomewide association study of citalopram response in major depressive disorder.
trait: Response to citalopram treatment
link:
http://www.ncbi.nlm.nih.gov/pubmed/19846067?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=1

initial_samplesize:
Up to 659 European ancestry responders, up to 121 African American responders, up to 103 Hispanic responders, 408 European ancestry non-responders, 120 African American non-responders, 80 Hispanic non-responders


dbdate: 11/09/2009
author: Han JW
date: 10/18/2009
journal: Nat Genet
trait: Systemic lupus erythematosus
initial_samplesize: 1,047 Han Chinese ancestry cases, 1,205 Han Chinese ancestry controls
replication_samplesize: 3,152 Han Chinese ancestry cases, 7,050 Han Chinese ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19838193?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=2

study:
Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.


dbdate: 11/09/2009
author: Landi MT
date: 10/15/2009
journal: Am J Hum Genet
trait: Lung adenocarcinoma
initial_samplesize: 5,739 European ancestry cases, 5,848 European ancestry controls
replication_samplesize: 7,561 European ancestry cases, 13,818 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19836008?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=5

study:
A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.


dbdate: 11/05/2009
author: Benyamin B
date: 10/11/2009
journal: Nat Genet
study: Common variants in TMPRSS6 are associated with iron status and erythrocyte volume.
trait: Iron status biomarkers
initial_samplesize: 4,818 European ancestry individuals
replication_samplesize: 3,470 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/19820699?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 11/05/2009
author: Chambers JC
date: 10/11/2009
journal: Nat Genet
study: Genome-wide association study identifies variants in TMPRSS6 associated with hemoglobin levels.
trait: Hemoglobin
initial_samplesize: 6,316 European ancestry individuals, 9,685 Indian Asian ancestry individuals
replication_samplesize: 5,187 European ancestry individuals, 6,721 Indian Asian ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/19820698?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 11/03/2009
author: Ganesh SK
date: 10/11/2009
journal: Nat Genet
study: Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.
trait: Hematocrit
initial_samplesize: 24,167 European ancestry individuals
replication_samplesize: 9,456 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/19862010?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=1


dbdate: 10/30/2009
author: Soranzo N
date: 10/11/2009
journal: Nat Genet
trait: Hematological parameters
initial_samplesize: 4,627 European ancestry individuals
replication_samplesize: 9,316 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/19820697?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.


dbdate: 10/23/2009
author: Weiss LA
date: 10/08/2009
journal: Nature
study: A genome-wide linkage and association scan reveals novel loci for autism.
trait: Autism
initial_samplesize: 1,553 probands from 1,031 families
replication_samplesize: 2,073 trios
link:
http://www.ncbi.nlm.nih.gov/pubmed/19812673?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 10/16/2009
author: Rivadeneira F
date: 10/04/2009
journal: Nat Genet
trait: Bone mineral density (hip)
initial_samplesize: 19,195 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/19801982?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies.


dbdate: 11/04/2009
author: Hicks AA
date: 10/02/2009
journal: PLoS Genet
study: Genetic determinants of circulating sphingolipid concentrations in European populations.
trait: Sphingolipid levels
initial_samplesize: 4,110 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/19798445?ordinalpos=4&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 10/06/2009
author: Roeske D
date: 09/29/2009
journal: Mol Psychiatry
trait: Speech perception in dyslexia
initial_samplesize: 200 European ancestry cases
replication_samplesize: 186 European ancestry cases
link:
http://www.ncbi.nlm.nih.gov/pubmed/19786962?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
First genome-wide association scan on neurophysiological endophenotypes points to trans-regulation effects on SLC2A3 in dyslexic children.


dbdate: 10/06/2009
author: Nakanishi H
date: 09/25/2009
journal: PLoS Genet
trait: Myopia (pathological)
initial_samplesize: 297 Japanese ancestry cases, 934 Japanese ancestry controls
replication_samplesize: 533 Japanese ancestry cases, 977 Japanese ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19779542?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
A genome-wide association analysis identified a novel susceptible locus for pathological myopia at 11q24.1.


dbdate: 10/05/2009
author: Latourelle JC
date: 09/22/2009
journal: BMC Med Genet
study: Genomewide association study for onset age in Parkinson disease.
trait: Parkinson's disease (age of onset)
initial_samplesize: 857 European ancestry familial cases, 440 idiopathic cases
replication_samplesize: 747 European ancestry idiopathic cases
link:
http://www.ncbi.nlm.nih.gov/pubmed/19772629?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 12/29/2009
author: Eeles RA
date: 09/20/2009
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/19767753
trait: Prostate cancer
initial_samplesize: 1,854 European ancestry cases, 1,894 European ancestry controls
study:
Identification of seven new prostate cancer susceptibility loci through a genome-wide association study.

replication_samplesize:
19,879 cases and 18,761 controls of European, East Asian, African American, Latino, and Hawaiian ancestry


dbdate: 10/05/2009
author: Gudmundsson J
date: 09/20/2009
journal: Nat Genet
trait: Prostate cancer
initial_samplesize: Up to 1,968 European ancestry cases, 35,382 European ancestry controls
replication_samplesize: Up to 11,806 European ancestry cases, 12,387 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19767754?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Genome-wide association and replication studies identify four variants associated with prostate cancer susceptibility.


dbdate: 09/30/2009
author: Le Clerc S
date: 09/15/2009
journal: J Infect Dis
trait: AIDS
initial_samplesize: 85 European ancestry cases, 2,049 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19754311?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Genomewide association study of a rapid progression cohort identifies new susceptibility alleles for AIDS (ANRS Genomewide Association Study 03).


dbdate: 09/30/2009
author: Suppiah V
date: 09/13/2009
journal: Nat Genet
study: IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy.
trait: Response to hepatitis C treatment
initial_samplesize: 131 European ancestry responders, 162 European ancestry non-responders
replication_samplesize: 261 European ancestry responders, 294 European ancestry non-responders
link:
http://www.ncbi.nlm.nih.gov/pubmed/19749758?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 09/30/2009
author: Tanaka Y
date: 09/13/2009
journal: Nat Genet
trait: Response to hepatitis C treatment
initial_samplesize: 64 Japanese ancestry responders, 78 Japanese ancestry non-responders
replication_samplesize: 122 Japanese ancestry responders, 50 Japanese ancestry non-responders
link:
http://www.ncbi.nlm.nih.gov/pubmed/19749757?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C.


dbdate: 09/29/2009
author: Harold D
date: 09/06/2009
journal: Nat Genet
trait: Alzheimer's disease
initial_samplesize: 3,941 European ancestry cases, 7,848 European ancestry controls
replication_samplesize: 2,023 European ancestry cases, 2,340 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19734902?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease.


dbdate: 09/29/2009
author: Lambert JC
date: 09/06/2009
journal: Nat Genet
trait: Alzheimer's disease
initial_samplesize: 2,032 European ancestry cases, 5,328 European ancestry controls
replication_samplesize: 3,978 European ancestry cases, 3,297 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19734903?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease.


dbdate: 09/29/2009
author: Rung J
date: 09/06/2009
journal: Nat Genet
trait: Type 2 diabetes and other traits
initial_samplesize: 679 French ancestry cases, 697 French ancestry controls
replication_samplesize: 5,579 European ancestry cases, 7,096 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19734900?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia.


dbdate: 09/29/2009
author: van Es MA
date: 09/06/2009
journal: Nat Genet
trait: Amyotrophic lateral sclerosis
initial_samplesize: 2,323 European ancestry cases, 9,013 European ancestry controls
replication_samplesize: 2,532 European ancestry cases, 5,940 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19734901?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis.


dbdate: 11/08/2012
author: Need AC
date: 09/04/2009
journal: Hum Mol Genet
study: A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.
trait: Cognitive performance
initial_samplesize: Up to 1,295 individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/19734545?ordinalpos=4&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 09/28/2009
author: Paterson AD
date: 09/03/2009
journal: Arterioscler Thromb Vasc Biol
trait: Soluble E-selectin levels
initial_samplesize: 685 European ancestry individuals with type 1 diabetes
replication_samplesize: 477 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/19729612?ordinalpos=5&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Genome-wide association identifies the ABO blood group as a major locus associated with serum levels of soluble E-selectin.


dbdate: 09/28/2009
author: Tonjes A
date: 09/03/2009
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/19729412
trait: Height
initial_samplesize: 929 Sorbian individuals
replication_samplesize: 5,758 European ancestry individuals
study:
Genetic variation in GPR133 is associated with height: genome wide association study in the self-contained population of Sorbs.


dbdate: 09/28/2009
author: De Moor MH
date: 09/02/2009
journal: Med Sci Sports Exerc
study: Genome-wide association study of exercise behavior in Dutch and American adults.
trait: Exercise (leisure time)
initial_samplesize: 2,622 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/19727025?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 09/28/2009
author: McClay JL
date: 09/01/2009
journal: Mol Psychiatry
study: Genome-wide pharmacogenomic analysis of response to treatment with antipsychotics.
trait: Response to antipsychotic treatment
initial_samplesize: 494 European ancestry cases, 244 African American and other ancestry cases
link:
http://www.ncbi.nlm.nih.gov/pubmed/19721433?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 09/09/2009
author: Hancock DB
date: 08/28/2009
journal: PLoS Genet
trait: Asthma (childhood onset)
initial_samplesize: 492 Mexican ancestry trios
replication_samplesize: 177 Mexican ancestry trios
link:
http://www.ncbi.nlm.nih.gov/pubmed/19714205?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Genome-wide association study implicates chromosome 9q21.31 as a susceptibility locus for asthma in mexican children.


dbdate: 09/24/2009
author: Liu YZ
date: 08/28/2009
journal: PLoS One
trait: Obesity and osteoporosis
initial_samplesize: 499 European ancestry males, 501 European ancestry females
replication_samplesize: 1,370 European ancestry males and 1,985 European ancestry females from 975 families
link:
http://www.ncbi.nlm.nih.gov/pubmed/19714249?ordinalpos=5&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Powerful bivariate genome-wide association analyses suggest the SOX6 gene influencing both obesity and osteoporosis phenotypes in males.


dbdate: 09/09/2009
author: Shuldiner AR
date: 08/26/2009
journal: JAMA
link: http://www.ncbi.nlm.nih.gov/pubmed/19706858
trait: Response to clopidogrel therapy
initial_samplesize: 429 Amish individuals
replication_samplesize: 140 European ancestry individuals, 83 African American individuals, 4 Other ancestry individuals
study:
Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy.


