# studies

dbdate: 09/09/2009
author: Cui R
date: 08/18/2009
journal: Gastroenterology
link: http://www.ncbi.nlm.nih.gov/pubmed/19698717
trait: Esophageal cancer
initial_samplesize: 182 Japanese ancestry cases, 927 Japanese ancestry controls
replication_samplesize: 782 Japanese ancestry cases, 1,898 Japanese ancestry controls
study:
Functional variants in ADH1B and ALDH2 coupled with alcohol and smoking synergistically enhance esophageal cancer risk.


dbdate: 09/04/2009
author: Papaemmanuil E
date: 08/16/2009
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/19684604
trait: Acute lymphoblastic leukemia (childhood)
initial_samplesize: 907 European ancestry cases, 2,398 European ancestry controls
study:
Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia.


dbdate: 09/11/2009
author: Trevino LR
date: 08/16/2009
journal: Nat Genet
study: Germline genomic variants associated with childhood acute lymphoblastic leukemia.
trait: Acute lymphoblastic leukemia (childhood)
initial_samplesize: 317 European descent cases, 17,958 European descent controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19684603?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 09/04/2009
author: Alkelai A
date: 08/13/2009
journal: Psychopharmacology (Berl)
trait: Response to antipsychotic treatment
link:
http://www.ncbi.nlm.nih.gov/pubmed/19680635?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Genome-wide association study of antipsychotic-induced parkinsonism severity among schizophrenia patients.

initial_samplesize:
140 European ancestry cases, 57 African American cases, 2 Other ancestry cases, 117 European ancestry controls, 72 African American controls, 9 Other ancestry controls


dbdate: 09/09/2009
author: Potkin SG
date: 08/07/2009
journal: PLoS One
trait: Hippocampal atrophy
link:
http://www.ncbi.nlm.nih.gov/pubmed/19668339?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease.

initial_samplesize:
162 European ancestry cases, 7 African American cases, 1 Asian ancestry cases, 2 Other ancestry cases, 192 European ancestry controls, 14 African American controls, 3 Asian ancestry controls


dbdate: 09/04/2009
author: Tse KP
date: 08/05/2009
journal: Am J Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/19664746
trait: Nasopharyngeal carcinoma
initial_samplesize: 277 Han Chinese ancestry cases, 285 Han Chinese ancestry controls
replication_samplesize: 635 Han Chinese ancestry cases, 1,640 Han Chinese ancestry controls
study:
Genome-wide association study reveals multiple nasopharyngeal carcinoma-associated loci within the HLA region at chromosome 6p21.3.


dbdate: 09/14/2009
author: Broderick P
date: 08/04/2009
journal: Cancer Res
link: http://www.ncbi.nlm.nih.gov/pubmed/19654303
trait: Lung cancer
initial_samplesize: 1,952 European ancestry cases, 1,438 European ancestry controls
study:
Deciphering the impact of common genetic variation on lung cancer risk: a genome-wide association study.

replication_samplesize:
2,465 European ancestry cases, 3,005 European ancestry controls, 3,143 individuals, 3,762 individuals


dbdate: 09/04/2009
author: Chambers JC
date: 08/03/2009
journal: Diabetes
link: http://www.ncbi.nlm.nih.gov/pubmed/19651812
trait: Fasting plasma glucose
initial_samplesize: 698 Asian Indian ancestry cases, 6,776 Asian Indian ancestry controls
replication_samplesize: 4,462 European ancestry controls
study:
Common genetic variation near melatonin receptor MTNR1B contributes to raised plasma glucose and increased risk of type 2 diabetes among Indian Asians and European Caucasians.


dbdate: 09/04/2009
author: Grant SF
date: 08/03/2009
journal: J Pediatr
link: http://www.ncbi.nlm.nih.gov/pubmed/19656524
trait: Orofacial clefts
initial_samplesize: 111 European ancestry cases, 5,951 European ancestry controls
study:
A genome-wide association study identifies a locus for nonsyndromic cleft lip with or without cleft palate on 8q24.


dbdate: 09/04/2009
author: Amundadottir L
date: 08/02/2009
journal: Nat Genet
trait: Pancreatic cancer
initial_samplesize: 1,771 European ancestry cases, 1,805 European ancestry controls
replication_samplesize: 2,120 European ancestry cases, 2,127 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19648918?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer.


dbdate: 09/04/2009
author: Song H
date: 08/02/2009
journal: Nat Genet
study: A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2.
trait: Ovarian cancer
initial_samplesize: 1,817 European ancestry cases, 2,353 European ancestry controls
replication_samplesize: 6,944 European ancestry cases, 9,477 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19648919?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 08/21/2009
author: Wu X
date: 08/02/2009
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/19648920
trait: Bladder cancer
initial_samplesize: 969 European ancestry cases, 957 European ancestry controls
replication_samplesize: 5,698 European ancestry cases, 38,633 European ancestry controls
study:
Genetic variation in the prostate stem cell antigen gene PSCA confers susceptibility to urinary bladder cancer.


dbdate: 12/29/2009
author: Cheng YC
date: 08/01/2009
journal: Circ Cardiovasc Genet
trait: Matrix metalloproteinase levels
initial_samplesize: 778 Old Order Amish individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/20031604?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=2

study:
Genome-wide association scan identifies variants near Matrix Metalloproteinase (MMP) genes on chromosome 11q21-22 strongly associated with serum MMP-1 levels.


dbdate: 12/29/2009
author: Marroni F
date: 08/01/2009
journal: Circ Cardiovasc Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20031603
trait: QT interval
initial_samplesize: 2,325 European ancestry individuals
study:
A genome-wide association scan of RR and QT interval duration in 3 European genetically isolated populations: the EUROSPAN project.


dbdate: 08/21/2009
author: Skibola CF
date: 07/20/2009
journal: Nat Genet
study: Genetic variants at 6p21.33 are associated with susceptibility to follicular lymphoma.
trait: Follicular lymphoma
initial_samplesize: 189 European ancestry cases, 592 European controls
replication_samplesize: 456 European ancestry cases, 2,785 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19620980?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 08/12/2009
author: Adeyemo A
date: 07/17/2009
journal: PLoS Genet
study: A genome-wide association study of hypertension and blood pressure in African Americans.
trait: Hypertension
initial_samplesize: 509 African American cases, 508 African American controls
replication_samplesize: 366 West African ancestry cases, 614 West African ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19609347?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 08/04/2009
author: Benjamin EJ
date: 07/13/2009
journal: Nat Genet
study: Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry.
trait: Atrial fibrillation
initial_samplesize: 3,413 cases, 37,105 referents
replication_samplesize: 2,145 cases, 4,073 controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19597492?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 07/30/2009
author: Gudbjartsson DF
date: 07/13/2009
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/19597491
study: A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke.
trait: Atrial fibrillation
initial_samplesize: 2,385 European ancestry cases, 33,752 European ancestry controls
replication_samplesize:
up to 2,427 European ancestry cases, 3,379 European ancestry controls, 286 Han Chinese ancestry cases, 2,763 Han Chinese ancestry controls


dbdate: 07/24/2009
author: Nolte IM
date: 07/09/2009
journal: PLoS One
link: http://www.ncbi.nlm.nih.gov/pubmed/19587794
trait: QT interval
initial_samplesize: 3,558 European ancestry individuals
replication_samplesize: 29,527 European ancestry individuals
study:
Common genetic variation near the phospholamban gene is associated with cardiac repolarisation: meta-analysis of three genome-wide association studies.


dbdate: 08/07/2009
author: Vasan RS
date: 07/08/2009
journal: JAMA
trait: Aortic root size
initial_samplesize: 12,612 European ancestry individuals
replication_samplesize: 4,094 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/19584346?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data.


dbdate: 07/16/2009
author: Bishop DT
date: 07/05/2009
journal: Nat Genet
study: Genome-wide association study identifies three loci associated with melanoma risk.
trait: Melanoma
initial_samplesize: 1,539 European ancestry cases, 3,917 European ancestry controls
replication_samplesize: 2,312 European ancestry cases, 1,867 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19578364?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 07/13/2009
author: Falchi M
date: 07/05/2009
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/19578365
trait: Cutaneous nevi
initial_samplesize: 1,524 European ancestry twins
study:
Genome-wide association study identifies variants at 9p21 and 22q13 associated with development of cutaneous nevi.

replication_samplesize:
4,107 European ancestry individuals, 3,131 European ancestry cases, 4,276 European ancestry controls


dbdate: 07/12/2009
author: Shete S
date: 07/05/2009
journal: Nat Genet
study: Genome-wide association study identifies five susceptibility loci for glioma.
trait: Glioma
initial_samplesize: 1,878 European ancestry cases, 3,670 European ancestry controls
replication_samplesize: 2,545 European ancestry cases, 2,953 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19578367?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 07/12/2009
author: Wrensch M
date: 07/05/2009
journal: Nat Genet
study: Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility.
trait: Glioma (high-grade)
initial_samplesize: 692 European ancestry cases, 3,992 European ancestry controls
replication_samplesize: 176 cases, 174 controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19578366?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 07/24/2009
author: Estrada K
date: 07/01/2009
journal: Hum Mol Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/19570815
trait: Height
initial_samplesize: 10,074 European ancestry individuals
replication_samplesize: 6,912 European ancestry individuals
study:
A genome-wide association study of northwestern Europeans involves the C-type natriuretic peptide signaling pathway in the etiology of human height variation.


dbdate: 07/10/2009
author: Shi J
date: 07/01/2009
journal: Nature
link: http://www.ncbi.nlm.nih.gov/pubmed/19571809
study: Common variants on chromosome 6p22.1 are associated with schizophrenia.
trait: Schizophrenia
replication_samplesize: 5,327 European ancestry cases, 16,424 European ancestry controls
initial_samplesize:
2,681 European ancestry cases, 2,653 European ancestry controls, 1,286 African American cases, 973 African American controls


dbdate: 07/01/2009
author: Heard-Costa NL
date: 06/26/2009
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/19557197
trait: Waist circumference
initial_samplesize: 31,373 European ancestry individuals
replication_samplesize: 38,641 individuals
study:
NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium.


dbdate: 07/01/2009
author: Lindgren CM
date: 06/26/2009
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/19557161
trait: Adiposity
initial_samplesize: 38,580 European ancestry individuals
replication_samplesize: Up to 102,064 European ancestry individuals
study:
Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution.


dbdate: 06/30/2009
author: Bahlo
date: 06/14/2009
journal: Nat Genet
trait: Multiple sclerosis
initial_samplesize: 1,618 European ancestry cases, 3,413 European ancestry controls
replication_samplesize: 2,256 European ancestry cases, 2,310 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19525955?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20.


dbdate: 06/29/2009
author: De Jager PL
date: 06/14/2009
journal: Nat Genet
trait: Multiple sclerosis
initial_samplesize: 2,624 European ancestry cases, 7,220 European ancestry controls
replication_samplesize: 2,215 European ancestry cases, 2,116 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19525953?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.


dbdate: 06/17/2009
author: Gregersen PK
date: 06/07/2009
journal: Nat Genet
trait: Rheumatoid arthritis
initial_samplesize: 2,418 European ancestry cases, 4,504 European ancestry controls
replication_samplesize: 2,604 cases, 2,882 controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19503088?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis.


dbdate: 06/22/2009
author: Kolz M
date: 06/05/2009
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/19503597
trait: Uric acid levels
initial_samplesize: 12,328 European ancestry males, 15,813 European ancestry females
study:
Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations.


dbdate: 06/16/2009
author: Smith EN
date: 06/02/2009
journal: Mol Psychiatry
link: http://www.ncbi.nlm.nih.gov/pubmed/19488044
trait: Bipolar disorder
study:
Genome-wide association study of bipolar disorder in European American and African American individuals.

initial_samplesize:
1,001 European ancestry cases, 1,033 European ancestry controls, 345 African American cases, 670 African American controls

replication_samplesize:
1,550 European ancestry individuals from 250 families, 1,263 European ancestry cases, 431 European ancestry controls


dbdate: 06/15/2009
author: Daly AK
date: 05/31/2009
journal: Nat Genet
study: HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin.
trait: Drug-induced liver injury (flucloxacillin)
initial_samplesize: 58 European ancestry cases, 282 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19483685?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 06/14/2009
author: Rapley EA
date: 05/31/2009
journal: Nat Genet
study: A genome-wide association study of testicular germ cell tumor.
trait: Testicular germ cell tumor
initial_samplesize: 730 cases, 1,435 controls
replication_samplesize: 571 cases, 1,806 controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19483681?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 06/16/2009
author: Aston KI
date: 05/28/2009
journal: J Androl
link: http://www.ncbi.nlm.nih.gov/pubmed/19478329
trait: Male infertility
study:
Genome-wide study of single-nucleotide polymorphisms associated with azoospermia and severe oligozoospermia.

initial_samplesize:
52 European ancestry oligozoospermic cases, 40 European ancestry non-obstructive azoospermic cases, 80 European ancestry controls


dbdate: 06/10/2009
author: Ma D
date: 05/28/2009
journal: Ann Hum Genet
study: A genome-wide association study of autism reveals a common novel risk locus at 5p14.1.
trait: Autism
initial_samplesize: 1,390 European ancestry individuals from 438 families
replication_samplesize: 2,390 European ancestry individuals from 457 families
link:
http://www.ncbi.nlm.nih.gov/pubmed/19456320?ordinalpos=9&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 06/21/2009
author: Hirschfield GM
date: 05/20/2009
journal: N Engl J Med
study: Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants.
trait: Primary biliary cirrhosis
initial_samplesize: 505 European ancestry cases, 1,507 European ancestry controls
replication_samplesize: 526 Eurpopean ancestry cases, 1,206 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19458352?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 06/14/2009
author: Arnett DK
date: 05/19/2009
journal: BMC Med Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/19454037
trait: Left ventricular mass
initial_samplesize: 101 European ancestry cases, 101 European ancestry controls
replication_samplesize: 704 European ancestry individuals, 1,467 African American individuals
study:
Genome-wide association study identifies single-nucleotide polymorphism in KCNB1 associated with left ventricular mass in humans: the HyperGEN Study.


dbdate: 06/04/2009
author: Landers JE
date: 05/18/2009
journal: Proc Natl Acad Sci U S A
trait: Amyotrophic lateral sclerosis
initial_samplesize: 1,821 cases, 2,258 controls
replication_samplesize: 538 cases, 556 controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19451621?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Reduced expression of the Kinesin-Associated Protein 3 (KIFAP3) gene increases survival in sporadic amyotrophic lateral sclerosis.


dbdate: 06/04/2009
author: He C
date: 05/17/2009
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/19448621
trait: Menarche and menopause (age at onset)
initial_samplesize: 17,438 European ancestry women
study:
Genome-wide association studies identify loci associated with age at menarche and age at natural menopause.


dbdate: 06/01/2009
author: Ong KK
date: 05/17/2009
journal: Nat Genet
study: Genetic variation in LIN28B is associated with the timing of puberty.
trait: Menarche (age at onset)
initial_samplesize: 4,714 European ancestry women
replication_samplesize: 16,373 women
link:
http://www.ncbi.nlm.nih.gov/pubmed/19448623?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 05/28/2009
author: Perry JR
date: 05/17/2009
journal: Nat Genet
study: Meta-analysis of genome-wide association data identifies two loci influencing age at menarche.
trait: Menarche (age at onset)
initial_samplesize: 17,510 European ancestry women
link:
http://www.ncbi.nlm.nih.gov/pubmed/19448620?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 05/28/2009
author: Stolk L
date: 05/15/2009
journal: Nat Genet
study: Loci at chromosomes 13, 19 and 20 influence age at natural menopause.
trait: Menopause (age at onset)
initial_samplesize: 2,979 European ancestry women
replication_samplesize: 2,560 European ancestry women
link:
http://www.ncbi.nlm.nih.gov/pubmed/19448619?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 06/01/2009
author: Barrett JC
date: 05/10/2009
journal: Nat Genet
trait: Type 1 diabetes
initial_samplesize: 7,514 cases, 9,045 controls
replication_samplesize: 4,267 cases, 4,670 controls, 4,342 trios from 2,319 families
link:
http://www.ncbi.nlm.nih.gov/pubmed/19430480?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.


dbdate: 05/27/2009
author: Kottgen A
date: 05/10/2009
journal: Nat Genet
study: Multiple loci associated with indices of renal function and chronic kidney disease.
trait: Renal function and chronic kidney disease
initial_samplesize: 2,388 European ancestry cases, 17,489 European ancestry controls
replication_samplesize: 1,932 cases, 19,534 controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19430482?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 05/19/2009
author: Levy D
date: 05/10/2009
journal: Nat Genet
study: Genome-wide association study of blood pressure and hypertension.
trait: Diastolic blood pressure
initial_samplesize: 29,136 European ancestry individuals
replication_samplesize: 34,433 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/19430479?ordinalpos=4&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 05/19/2009
author: Newton-Cheh C
date: 05/10/2009
journal: Nat Genet
study: Genome-wide association study identifies eight loci associated with blood pressure.
trait: Diastolic blood pressure
initial_samplesize: 34,433 European ancestry individuals
replication_samplesize: Up to 100,347 European ancestry individuals, up to 12,889 Indian Asian ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/19430483?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 05/20/2009
author: Himes BE
date: 05/07/2009
journal: Am J Hum Genet
study: Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene.
trait: Asthma
initial_samplesize: 359 European ancestry cases, 846 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19426955?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

replication_samplesize:
2,981 European ancestry cases, 12,358 European ancestry controls, 769 European ancestry and hispanic cases, 1,007 European ancestry and hispanic controls, 592 Hispanic cases with their 1,184 Hispanic parental controls, 2,258 African American cases, 3,006 African American controls


dbdate: 05/19/2009
author: Sanna S
date: 05/06/2009
journal: Hum Mol Genet
trait: Bilirubin levels
initial_samplesize: 4,300 Sardinian individuals
replication_samplesize: 1,860 Sardinian individuals, 832 Old Order Amish individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/19419973?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia.


dbdate: 05/14/2009
author: Scott LJ
date: 05/05/2009
journal: Proc Natl Acad Sci U S A
study: Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry.
trait: Bipolar disorder
initial_samplesize: 3,683 European ancestry cases, 14,507 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19416921?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 05/12/2009
author: Johnson AD
date: 05/04/2009
journal: Hum Mol Genet
study: Genome-wide association meta-analysis for total serum bilirubin levels.
trait: Bilirubin levels
initial_samplesize: 9,464 individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/19414484?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 05/07/2009
author: Capasso M
date: 05/03/2009
journal: Nat Genet
study: Common variations in BARD1 influence susceptibility to high-risk neuroblastoma.
trait: Neuroblastoma (high-risk)
initial_samplesize: 397 European ancestry cases, 2,043 European ancestry controls
replication_samplesize: 371 European ancestry cases, 2,119 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19412175?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 05/07/2009
author: Hallmayer J
date: 05/03/2009
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/19412176
study: Narcolepsy is strongly associated with the T-cell receptor alpha locus.
trait: Narcolepsy
initial_samplesize: 807 European ancestry cases, 1,074 European ancestry controls
replication_samplesize:
363 European ancestry cases, 355 European ancestry  controls, 133 African American cases, 144 African American controls, 561 Asian ancestry cases, 605 Asian ancestry controls


dbdate: 05/07/2009
author: Takeuchi F
date: 04/29/2009
journal: Diabetes
link: http://www.ncbi.nlm.nih.gov/pubmed/19401414
trait: Type 2 diabetes
initial_samplesize: 519 Japanese ancestry cases, 503 Japanese ancestry controls
replication_samplesize: 5,110 Japanese ancestry cases, 6,867 Japanese ancestry controls
study:
Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population.


dbdate: 05/11/2009
author: Wang K
date: 04/28/2009
journal: Nature
study: Common genetic variants on 5p14.1 associate with autism spectrum disorders.
trait: Autism
link:
http://www.ncbi.nlm.nih.gov/pubmed/19404256?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

initial_samplesize:
3,101 European ancestry individuals from 780 families, 1,204 European ancestry cases, 6,491 European ancestry controls

replication_samplesize:
1,390 European ancestry individuals from 447 families, 108 European ancestry cases, 540 European ancestry controls


dbdate: 05/05/2009
author: Cho YS
date: 04/26/2009
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/19396169
trait: Biomedical quantitative traits
initial_samplesize: 8,842 Korean ancestry individuals
replication_samplesize: 7,861 Korean ancestry individuals
study:
A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits.


dbdate: 04/22/2009
author: Poduslo SE
date: 04/14/2009
journal: Am J Med Genet B Neuropsychiatr Genet
trait: Aging
link:
http://www.ncbi.nlm.nih.gov/pubmed/19367585?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
A genome screen of successful aging without cognitive decline identifies LRP1B by haplotype analysis.

initial_samplesize:
89 European ancestry and African American successfully aged individuals, 227 European ancestry Alzheimers cases


dbdate: 05/05/2009
author: Hiura Y
date: 04/10/2009
journal: Circ J
link: http://www.ncbi.nlm.nih.gov/pubmed/19359809
trait: HDL cholesterol
initial_samplesize: 900 Japanese ancestry individuals
replication_samplesize: 1,810 Japanese ancestry individuals
study:
Identification of genetic markers associated with high-density lipoprotein-cholesterol by genome-wide screening in a Japanese population: the Suita study.


dbdate: 04/22/2009
author: Mangino M
date: 04/08/2009
journal: J Med Genet
trait: Telomere length
initial_samplesize: 1,625 European ancestry women
replication_samplesize: 1,165 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/19359265?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
A genome-wide association study identifies a novel locus on chromosome 18q12.2 influencing white cell telomere length.


dbdate: 04/14/2009
author: Esparza-Gordillo J
date: 04/06/2009
journal: Nat Genet
study: A common variant on chromosome 11q13 is associated with atopic dermatitis.
trait: Atopic dermatitis
replication_samplesize: 2,637 European ancestry cases, 3,957 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19349984?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

initial_samplesize:
939 European ancestry cases, 975 European ancestry controls, 1,097 European ancestry individuals from 270 families


dbdate: 04/16/2009
author: Kamatani Y
date: 04/06/2009
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/19349983
trait: Hepatitis B
initial_samplesize: 179 Japanese ancestry cases, 934 Japanese ancestry controls
study:
A genome-wide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians.

replication_samplesize:
1,599 Japanese ancestry cases, 2,821 Japanese ancestry controls, 308 Thai ancestry cases, 546 Thai ancestry controls


dbdate: 04/22/2009
author: Soranzo N
date: 04/03/2009
journal: PLoS Genet
trait: Height
initial_samplesize: 12,611 European ancestry individuals
replication_samplesize: 7,187 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/19343178?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Meta-analysis of genome-wide scans for human adult stature identifies novel Loci and associations with measures of skeletal frame size.


dbdate: 04/13/2009
author: Nan H
date: 04/02/2009
journal: J Invest Dermatol
study: Genome-wide association study of tanning phenotype in a population of European ancestry.
trait: Tanning
initial_samplesize: 2,287 European ancestry women
replication_samplesize: 870 European ancestry women
link:
http://www.ncbi.nlm.nih.gov/pubmed/19340012?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 12/29/2009
author: Danik JS
date: 04/01/2009
journal: Circ Cardiovasc Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20031577
trait: Fibrinogen
initial_samplesize: 17,686 European ancestry women
study:
Novel loci, including those related to Crohn disease, psoriasis, and inflammation, identified in a genome-wide association study of fibrinogen in 17 686 women: the Women's Genome Health Study.


dbdate: 12/29/2009
author: Dehghan A
date: 04/01/2009
journal: Circ Cardiovasc Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20031576
trait: Fibrinogen
initial_samplesize: 22,096 European ancestry individuals
replication_samplesize: 17,686 European ancestry women
study:
Association of novel genetic Loci with circulating fibrinogen levels: a genome-wide association study in 6 population-based cohorts.


dbdate: 12/29/2009
author: Pare G
date: 04/01/2009
journal: Circ Cardiovasc Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20031578
trait: Homocysteine levels
initial_samplesize: 13,974 European ancestry females
replication_samplesize: 840 European ancestry females
study:
Novel associations of CPS1, MUT, NOX4, and DPEP1 with plasma homocysteine in a healthy population: a genome-wide evaluation of 13 974 participants in the Women's Genome Health Study.


dbdate: 04/03/2009
author: Thomas G
date: 03/29/2009
journal: Nat Genet
trait: Breast cancer
initial_samplesize: 1,145 European ancestry cases, 1,142 European ancestry controls
replication_samplesize: 8,625 European ancestry cases, 9,657 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19330030?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1).


dbdate: 03/31/2009
author: Newton-Cheh C
date: 03/22/2009
journal: Nat Genet
study: Common variants at ten loci influence QT interval duration in the QTGEN Study.
trait: QT interval
initial_samplesize: 13,685 European ancestry individuals
replication_samplesize: 15,854 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/19305408?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 04/02/2009
author: Pfeufer A
date: 03/22/2009
journal: Nat Genet
study: Common variants at ten loci modulate the QT interval duration in the QTSCD Study.
trait: QT interval
initial_samplesize: 15,842 European ancestry individuals
replication_samplesize: up to 13,602 individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/19305409?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 04/02/2009
author: Org E
date: 03/20/2009
journal: Hum Mol Genet
trait: Hypertension
initial_samplesize: 364 European ancestry cases, 590 European ancestry controls
replication_samplesize: 1,043 European ancestry cases, 1,769 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19304780?ordinalpos=4&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Genome-wide scan identifies CDH13 as a novel susceptibility locus contributing to blood pressure determination in two European populations.


dbdate: 03/31/2009
author: Pillai SG
date: 03/20/2009
journal: PLoS Genet
trait: Chronic obstructive pulmonary disease
initial_samplesize: 823 cases, 810 controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19300482?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci.

replication_samplesize:
1,891 European ancestry individuals from 606 families, 389 European ancestry cases, 472 European ancestry controls, 949 individuals from 127 families


dbdate: 03/30/2009
author: Takeuchi F
date: 03/20/2009
journal: PLoS Genet
trait: Warfarin maintenance dose
initial_samplesize: 1,053 European ancestry individuals
replication_samplesize: 588 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/19300499?ordinalpos=4&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
A genome-wide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinants of warfarin dose.


dbdate: 03/31/2009
author: Wilk JB
date: 03/20/2009
journal: PLoS Genet
study: A genome-wide association study of pulmonary function measures in the Framingham Heart Study.
trait: Pulmonary function
initial_samplesize: 7,691 European ancestry individuals
replication_samplesize: 835 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/19300500?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 04/01/2009
author: Tanaka T
date: 03/18/2009
journal: Am J Hum Genet
trait: Folate pathway vitamin levels
initial_samplesize: 2,934 European ancestry individuals
replication_samplesize: 686 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/19303062?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Genome-wide association study of vitamin B6, vitamin B12, folate, and homocysteine blood concentrations.


dbdate: 03/31/2009
author: Kilpivaara O
date: 03/15/2009
journal: Nat Genet
trait: Myeloproliferative neoplasms
initial_samplesize: 324 European ancestry cases, 2,999 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19287384?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
A germline JAK2 SNP is associated with predisposition to the development of JAK2(V617F)-positive myeloproliferative neoplasms.


dbdate: 03/31/2009
author: Cui J
date: 03/14/2009
journal: Mol Med
trait: Anti-cyclic Citrullinated Peptide Antibody
initial_samplesize: 531 European ancestry cases
replication_samplesize: 849 European ancestry cases
link:
http://www.ncbi.nlm.nih.gov/pubmed/19287509?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Genome-wide association study of determinants of anti-cyclic citrullinated peptide antibody titer in adults with rheumatoid arthritis.


dbdate: 03/30/2009
author: Tregouet DA
date: 03/10/2009
journal: Blood
trait: Venous thromboembolism
initial_samplesize: 419 European ancestry cases, 1,228 European ancestry controls
replication_samplesize: 1,757 European ancestry cases, 1,480 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19278955?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Common susceptibility alleles are unlikely to contribute as strongly as the FV and ABO loci to VTE risk: results from a GWAS approach.


dbdate: 03/28/2009
author: Birnbaum S
date: 03/08/2009
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/19270707
trait: Orofacial clefts
initial_samplesize: 224 European ancestry cases, 383 European ancestry controls
replication_samplesize: 246 cases, 954 controls
study:
Key susceptibility locus for nonsyndromic cleft lip with or without cleft palate on chromosome 8q24.


dbdate: 03/24/2009
author: Liu XG
date: 03/04/2009
journal: Am J Hum Genet
trait: Body mass (lean)
initial_samplesize: 973 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/19268274?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Genome-wide association and replication studies identified TRHR as an important gene for lean body mass.

replication_samplesize:
1,488 European ancestry individuals,  1,972 European ancestry individuals from 593 families, 2,955 Chinese ancestry individuals


dbdate: 04/01/2009
author: Caporaso N
date: 02/27/2009
journal: PLoS One
study: Genome-wide and candidate gene association study of cigarette smoking behaviors.
trait: Smoking behavior
initial_samplesize: 2,617 European ancestry smokers, 1,725 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19247474?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 03/18/2009
author: Xiong DH
date: 02/25/2009
journal: Am J Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/19249006
trait: Bone mineral density
initial_samplesize: 1,000 European ancestry individuals
study:
Genome-wide association and follow-up replication studies identified ADAMTS18 and TGFBR3 as bone mass candidate genes in different ethnic groups.

replication_samplesize:
4,925 European ancestry individuals, 350 Chinese ancestry hip fracture cases, 350 Chinese ancestry hip fracture controls, 2,955 Chinese ancestry individuals, 908 West African ancestry men


dbdate: 03/01/2009
author: Schrauwen I
date: 02/18/2009
journal: Am J Hum Genet
study: A genome-wide analysis identifies genetic variants in the RELN gene associated with otosclerosis.
trait: Otosclerosis
initial_samplesize: 302 cases, 302 controls
replication_samplesize: 847 cases, 872 controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19230858?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 05/07/2009
author: Smith JG
date: 02/15/2009
journal: Heart Rhythm
link: http://www.ncbi.nlm.nih.gov/pubmed/19389651
trait: Electrocardiographic conduction measures
initial_samplesize: 1,262 Kosraen individuals
study:
Genome-wide association study of electrocardiographic conduction measures in an isolated founder population: Kosrae.


dbdate: 02/28/2009
author: Zheng W
date: 02/15/2009
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/19219042
study: Genome-wide association study identifies a new breast cancer susceptibility locus at 6q25.1.
trait: Breast cancer
initial_samplesize: 1,505 Chinese ancestry cases, 1,522 Chinese ancestry controls
replication_samplesize:
5,026 Chinese ancestry cases, 2,476 Chinese ancestry controls, 1,591 European ancestry cases, 1,466 European ancestry controls


dbdate: 02/28/2009
author: Soranzo N
date: 02/12/2009
journal: Blood
study: A novel variant on chromosome 7q22.3 associated with mean platelet volume, counts, and function.
trait: Mean platelet volume
initial_samplesize: 1,221 individuals
replication_samplesize: 7,365 individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/19221038?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 03/01/2009
author: Erdmann J
date: 02/08/2009
journal: Nat Genet
study: New susceptibility locus for coronary artery disease on chromosome 3q22.3.
trait: Coronary heart disease
initial_samplesize: 1,222 European ancestry cases, 1,298 European ancestry controls
replication_samplesize: 18,185 European ancestry cases, 20,068 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19198612?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 03/01/2009
author: Kathiresan S
date: 02/08/2009
journal: Nat Genet
trait: Myocardial infarction (early onset)
initial_samplesize: 2,967 European ancestry cases, 3,075 European ancestry controls
replication_samplesize: 9,746 European ancestry cases, 9,746 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19198609?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants.


dbdate: 02/28/2009
author: Gudmundsson J
date: 02/06/2009
journal: Nat Genet
study: Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in European populations.
trait: Thyroid cancer
initial_samplesize: 192 European ancestry cases, 37,196 European ancestry controls
replication_samplesize: 432 European ancestry cases, 1,727 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19198613?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 10/15/2009
author: Lowe JK
date: 02/06/2009
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/19197348
trait: Quantitative traits
initial_samplesize: 2,906 Kosraen individuals
study:
Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae.


dbdate: 02/28/2009
author: Kim SH
date: 02/01/2009
journal: Clin Exp Allergy
link: http://www.ncbi.nlm.nih.gov/pubmed/19187332
trait: Asthma (toluene diisocyanate-induced)
initial_samplesize: 84 Korean ancestry cases, 263 Korean ancestry controls
study:
Alpha-T-catenin (CTNNA3) gene was identified as a risk variant for toluene diisocyanate-induced asthma by genome-wide association analysis.


dbdate: 03/30/2009
author: Polasek O
date: 02/01/2009
journal: Croat Med J
study: Genome-wide association study of anthropometric traits in Korcula Island, Croatia.
trait: Anthropometric traits
initial_samplesize: 898 Korculan's individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/19260139?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 12/29/2009
author: Ridker PM
date: 02/01/2009
journal: Circ Cardiovasc Genet
trait: HDL cholesterol
initial_samplesize: 18,245 European ancestry females
link:
http://www.ncbi.nlm.nih.gov/pubmed/20031564?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=6

study:
Polymorphism in the CETP gene region, HDL cholesterol, and risk of future myocardial infarction: Genomewide analysis among 18 245 initially healthy women from the Women's Genome Health Study.


dbdate: 02/25/2009
author: Stefansson H
date: 02/01/2009
journal: Nat Genet
study: Variant in the sequence of the LINGO1 gene confers risk of essential tremor.
trait: Essential tremor
initial_samplesize: 452 European ancestry cases, 14,378 European ancestry controls
replication_samplesize: 301 European ancestry cases, 1,419 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19182806?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 03/31/2009
author: Zemunik T
date: 02/01/2009
journal: Croat Med J
study: Genome-wide association study of biochemical traits in Korcula Island, Croatia.
trait: Biochemical measures
initial_samplesize: 898 Korculan individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/19260141?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 02/28/2009
author: Ferrucci L
date: 01/29/2009
journal: Am J Hum Genet
trait: Carotenoid and tocopherol levels
initial_samplesize: 1,191 European ancestry individuals
replication_samplesize: 2,540 European ancestry individuals, 211 individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/19185284?ordinalpos=9&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Common variation in the beta-carotene 15,15'-monooxygenase 1 gene affects circulating levels of carotenoids: a genome-wide association study.


dbdate: 02/26/2009
author: Yang JJ
date: 01/28/2009
journal: JAMA
trait: Response to treatment for acute lymphoblastic leukemia
initial_samplesize: 356 European ancestry cases, 53 Black cases, 78 Other ancestry cases
link:
http://www.ncbi.nlm.nih.gov/pubmed/19176441?ordinalpos=9&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia.


dbdate: 02/06/2009
author: Nair RP
date: 01/25/2009
journal: Nat Genet
study: Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways.
trait: Psoriasis
initial_samplesize: 1,359 European ancestry cases, 1,400 European ancestry controls
replication_samplesize: 5,048 European ancestry cases, 5,041 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19169254?ordinalpos=4&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 02/07/2009
author: Zhang XJ
date: 01/25/2009
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/19169255
trait: Psoriasis
initial_samplesize: 1,139 Han Chinese ancestry cases, 1,132 Han Chinese ancestry controls
replication_samplesize: 5,721 Chinese ancestry cases, 7,340 Chinese ancestry controls
study:
Psoriasis genome-wide association study identifies susceptibility variants within LCE gene cluster at 1q21.


dbdate: 02/25/2009
author: Ling H
date: 01/22/2009
journal: Obesity (Silver Spring)
trait: Adiponectin levels
initial_samplesize: 997 European ancestry cases, 989 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19165155?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Genome-wide linkage and association analyses to identify genes influencing adiponectin levels: the GEMS Study.


dbdate: 03/03/2009
author: Meyre D
date: 01/18/2009
journal: Nat Genet
trait: Obesity
link:
http://www.ncbi.nlm.nih.gov/pubmed/19151714?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations.

initial_samplesize:
695 European ancestry obese adults, 731 European ancestry lean adults, 685 European ancestry obese children, 685 European ancestry lean children

replication_samplesize:
1,171 European ancestry obese adults, 1,114 European ancestry lean adults, 4,417 European ancestry adults, 856 European ancestry obese children, European ancestry 1,297 lean children and young adults, 5,291 European ancestry children


dbdate: 02/27/2009
author: Carrasquillo MM
date: 01/11/2009
journal: Nat Genet
study: Genetic variation in PCDH11X is associated with susceptibility to late-onset Alzheimer's disease.
trait: Alzheimer's disease
initial_samplesize: 844 European ancestry cases, 1,255 European ancestry controls
replication_samplesize: 1,547 European ancestry cases, 1,209 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19136949?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 01/21/2009
author: Burgner D
date: 01/09/2009
journal: PLoS Genet
trait: Kawasaki disease
initial_samplesize: 107 European ancestry cases, 134 European ancestry controls
replication_samplesize: 583 European ancestry cases, 1,357 European ancestry controls from 583 families
link:
http://www.ncbi.nlm.nih.gov/pubmed/19132087?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
A genome-wide association study identifies novel and functionally related susceptibility Loci for Kawasaki disease.


dbdate: 02/25/2009
author: Feulner TM
date: 01/07/2009
journal: Mol Psychiatry
study: Examination of the current top candidate genes for AD in a genome-wide association study.
trait: Alzheimer's disease
initial_samplesize: 491 European ancestry cases, 479 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19125160?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 01/21/2009
author: Ober C
date: 01/07/2009
journal: J Lipid Res
trait: Lp (a) levels
initial_samplesize: 357 Hutterite individuals
replication_samplesize: 1,054 European ancestry males
link:
http://www.ncbi.nlm.nih.gov/pubmed/19124843?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Genome-wide association study of plasma lipoprotein(a) levels identifies multiple genes on chromosome 6q.


dbdate: 01/21/2009
author: Silverberg MS
date: 01/04/2009
journal: Nat Genet
study: Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study.
trait: Ulcerative colitis
initial_samplesize: 1,022 European ancestry cases, 2,503 European ancestry controls
replication_samplesize: 1,387 European ancestry cases, 1,115 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19122664?ordinalpos=4&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 01/21/2009
author: Beecham GW
date: 01/03/2009
journal: Am J Hum Genet
trait: Alzheimer's disease
initial_samplesize: 492 European ancestry cases, 496 European ancestry controls
replication_samplesize: 238 European ancestry cases, 220 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19118814?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Genome-wide association study implicates a chromosome 12 risk locus for late-onset Alzheimer disease.


dbdate: 02/27/2009
author: Hinks A
date: 01/01/2009
journal: Arthritis Rheum
trait: Arthritis (juvenile idiopathic)
initial_samplesize: 279 European ancestry cases, 184 European ancestry controls
replication_samplesize: up to 654 European ancestry cases, 2,024 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19116933?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Identification of a novel susceptibility locus for juvenile idiopathic arthritis by genome-wide association analysis.


dbdate: 01/16/2009
author: Limou S
date: 01/01/2009
journal: J Infect Dis
trait: AIDS progression
replication_samplesize: (see Fellay 2007)
link:
http://www.ncbi.nlm.nih.gov/pubmed/19115949?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Genomewide association study of an AIDS-nonprogression cohort emphasizes the role played by HLA genes (ANRS Genomewide Association Study 02).

initial_samplesize:
275 European ancestry seropositive non-progressors, 86 European ancestry seropositive rapid progressors, 1,352 European ancestry seronegative controls


dbdate: 02/26/2009
author: Sun J
date: 01/01/2009
journal: Cancer Res
study: Sequence variants at 22q13 are associated with prostate cancer risk.
trait: Prostate cancer
initial_samplesize: 1,235 European ancestry aggressive cases, 1,599 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19117981?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

replication_samplesize:
1,215 European ancestry aggressive cases, 2,213 European ancestry non-aggressive cases, 1,208 European ancestry controls, 1,034 aggressive cases, 921 non-aggressive cases, 2,231 controls


dbdate: 01/14/2009
author: Wang Y
date: 12/29/2008
journal: Proc Natl Acad Sci U S A
trait: Blood pressure
initial_samplesize: 542 Old Order Amish individuals
replication_samplesize: 5,229 European ancestry individuals, 1,347 Amish individuals, 575 Hutterite individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/19114657?ordinalpos=13&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
From the Cover: Whole-genome association study identifies STK39 as a hypertension susceptibility gene.


dbdate: 01/14/2009
author: Meisinger C
date: 12/24/2008
journal: Am J Hum Genet
study: A genome-wide association study identifies three loci associated with mean platelet volume.
trait: Mean platelet volume
initial_samplesize: 1,606 European ancestry individuals
replication_samplesize: 8,617 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/19110211?ordinalpos=4&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 02/04/2009
author: Muglia P
date: 12/23/2008
journal: Mol Psychiatry
trait: Major depressive disorder
initial_samplesize: 1,359 European ancestry cases, 1,782 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19107115?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Genome-wide association study of recurrent major depressive disorder in two European case-control cohorts.


dbdate: 06/22/2009
author: Pare G
date: 12/19/2008
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/19096518
trait: Glycated hemoglobin levels
initial_samplesize: 14,618 European ancestry women
replication_samplesize: 455 European ancestry individuals
study:
Novel association of HK1 with glycated hemoglobin in a non-diabetic population: a genome-wide evaluation of 14,618 participants in the Women's Genome Health Study.


dbdate: 01/14/2009
author: Benyamin B
date: 12/17/2008
journal: Am J Hum Genet
study: Variants in TF and HFE explain approximately 40% of genetic variation in serum-transferrin levels.
trait: Iron status biomarkers
initial_samplesize: 411 European ancestry individuals from 150 families
link:
http://www.ncbi.nlm.nih.gov/pubmed/19084217?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 01/14/2009
author: Pollin TI
date: 12/17/2008
journal: Science
trait: Triglycerides
initial_samplesize: 809 Old Order Amish individuals
replication_samplesize: 698 Old Order Amish individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/19074352?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
A null mutation in human APOC3 confers a favorable plasma lipid profile and apparent cardioprotection.


dbdate: 01/16/2009
author: Styrkarsdottir U
date: 12/14/2008
journal: Nat Genet
study: New sequence variants associated with bone mineral density.
trait: Bone mineral density (hip)
initial_samplesize: 6,865 European ancestry individuals
replication_samplesize: 8,510 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/19079262?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 01/15/2009
author: Thorleifsson G
date: 12/14/2008
journal: Nat Genet
trait: Body mass index
initial_samplesize: 72,598 European ancestry individuals, 1,160 African American individuals
replication_samplesize: Up to 11,036 European ancestry individuals, 32,615 individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/19079260?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity.


dbdate: 01/12/2009
author: Willer CJ
date: 12/14/2008
journal: Nat Genet
trait: Body mass index
initial_samplesize: 32,387 European ancestry individuals
replication_samplesize: 59,082 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/19079261?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation.


dbdate: 02/05/2009
author: Mead S
date: 12/11/2008
journal: Lancet Neurol
study: Genetic risk factors for variant Creutzfeldt-Jakob disease: a genome-wide association study.
trait: Creutzfeldt-Jakob disease
initial_samplesize: 117 European ancestry cases, 3,083 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19081515?ordinalpos=5&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

replication_samplesize:
2 European ancestry vCJD cases, 506 Oceania ancestry sCJD cases, 28 Oceania ancestry iCJD cases, 151 Oceania ancestry Kuru cases, 125 Oceania ancestry Kuru resistant cases, 3,608 European ancestry controls, 562 Oceania ancestry controls


dbdate: 01/12/2009
author: Aulchenko YS
date: 12/07/2008
journal: Nat Genet
study: Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.
trait: Cholesterol, total
initial_samplesize: 21,848 European ancestry individuals, 714 Orcadian individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/19060911?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 01/07/2009
author: Bouatia-Naji N
date: 12/07/2008
journal: Nat Genet
trait: Fasting plasma glucose
initial_samplesize: 2,151 European ancestry individuals
replication_samplesize: 16,094 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/19060909?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk.


dbdate: 01/12/2009
author: Kathiresan S
date: 12/07/2008
journal: Nat Genet
study: Common variants at 30 loci contribute to polygenic dyslipidemia.
trait: HDL cholesterol
initial_samplesize: 19,840 European ancestry individuals
replication_samplesize: Up to 20,623 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/19060906?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 01/12/2009
author: Sabatti C
date: 12/07/2008
journal: Nat Genet
study: Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.
trait: HDL cholesterol
initial_samplesize: 4,763 Northern Finnish individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/19060910?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 05/07/2009
author: Lasky-Su J
date: 12/05/2008
journal: Am J Med Genet B Neuropsychiatr Genet
trait: Attention deficit hyperactivity disorder
initial_samplesize: 930 European ancestry trios
link:
http://www.ncbi.nlm.nih.gov/pubmed/18821565?ordinalpos=8&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations.


dbdate: 05/07/2009
author: Lasky-Su J
date: 12/05/2008
journal: Am J Med Genet B Neuropsychiatr Genet
study: Genome-wide association scan of the time to onset of attention deficit hyperactivity disorder.
trait: Attention deficit hyperactivity disorder (time to onset)
initial_samplesize: 930 European ancestry trios
link:
http://www.ncbi.nlm.nih.gov/pubmed/18937294?ordinalpos=5&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 01/15/2009
author: Timpson NJ
date: 12/03/2008
journal: Diabetes
trait: Type 2 diabetes
replication_samplesize: Up to 3,757 European ancestry cases, up to 5,346 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19056611?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Adiposity-related heterogeneity in patterns of type 2 diabetes susceptibility observed in genome-wide association data.

initial_samplesize:
958 European ancestry obese cases, 955 European ancestry non-obese cases, 2,938 European ancestry controls


dbdate: 02/26/2009
author: Prokopenko I
date: 12/01/2008
journal: Nat Genet
study: Variants in MTNR1B influence fasting glucose levels.
trait: Fasting plasma glucose
initial_samplesize: 35,812 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/19060907?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 12/09/2008
author: Terracciano A
date: 11/24/2008
journal: Mol Psychiatry
study: Genome-wide association scan for five major dimensions of personality.
trait: Personality dimensions
initial_samplesize: 3,972 Sardinian individuals
replication_samplesize: 3,903 Other ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/18957941?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 01/06/2009
author: Potkin SG
date: 11/20/2008
journal: Schizophr Bull
trait: Brain imaging in schizophrenia (interaction)
initial_samplesize: 46 European ancestry cases, 60 European ancestry controls, 18 cases, 14 controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19023125?ordinalpos=4&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
A genome-wide association study of schizophrenia using brain activation as a quantitative phenotype.


dbdate: 12/01/2008
author: Houlston RS
date: 11/16/2008
journal: Nat Genet
trait: Colorectal cancer
initial_samplesize: 1,902 European ancestry cases, 1,929 European ancestry controls
replication_samplesize: 18,284 European ancestry cases, 18,926 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19011631?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer.


dbdate: 01/16/2009
author: Baranzini SE
date: 11/14/2008
journal: Hum Mol Genet
study: Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.
trait: Brain lesion load
initial_samplesize: 791 European ancestry cases, 883 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/19010793?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 12/09/2008
author: Aulchenko YS
date: 11/09/2008
journal: Nat Genet
study: Genetic variation in the KIF1B locus influences susceptibility to multiple sclerosis.
trait: Multiple sclerosis
initial_samplesize: 45 Dutch cases,195 Dutch controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18997785?ordinalpos=&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.SmartSearch&log$=citationsensor

replication_samplesize:
1,316 European ancestry cases, 1,423 European ancestry controls, 1,318 Other ancestry cases and 1,507 Other ancestry controls from 756 families


dbdate: 12/09/2008
author: Pankratz N
date: 11/06/2008
journal: Hum Genet
study: Genomewide association study for susceptibility genes contributing to familial Parkinson disease.
trait: Parkinson's disease (familial)
initial_samplesize: 1,119 European ancestry cases, 1,127 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18985386?ordinalpos=4&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 12/09/2008
author: Cronin S
date: 11/05/2008
journal: Eur J Hum Genet
study: Screening for replication of genome-wide SNP associations in sporadic ALS.
trait: Amyotrophic lateral sclerosis
initial_samplesize: 958 European ancestry cases, 932 European ancestry controls
replication_samplesize: 309 European ancestry cases, 404 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18987618?ordinalpos=6&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSu


dbdate: 11/25/2008
author: Cooper JD
date: 11/02/2008
journal: Nat Genet
trait: Type 1 diabetes
initial_samplesize: 3,561 European ancestry cases, 4,646 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18978792?ordinalpos=4&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci.

replication_samplesize:
6,225 European ancestry cases, 6,946 European ancestry controls, 3,064 European ancestry trios from 2,828 families


dbdate: 12/09/2008
author: McKay JD
date: 11/02/2008
journal: Nat Genet
study: Lung cancer susceptibility locus at 5p15.33.
trait: Lung cancer
initial_samplesize: 2,971 European ancestry cases, 3,746 European ancestry controls
replication_samplesize: 2,899 European ancestry cases, 5,573 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18978790?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Wang Y
date: 11/02/2008
journal: Nat Genet
study: Common 5p15.33 and 6p21.33 variants influence lung cancer risk.
trait: Lung cancer
initial_samplesize: 5,095 European ancestry cases, 5,200 European ancestry cases
replication_samplesize: 2,448 European ancestry cases, 2,983 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18978787?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 12/09/2008
author: Bertram L
date: 10/29/2008
journal: Am J Hum Genet
trait: Alzheimer's disease
initial_samplesize: 941 European ancestry cases and 404 European ancestry controls from 410 families
replication_samplesize: 1,767 European ancestry cases and 838 European ancestry controls from 875 families
link:
http://www.ncbi.nlm.nih.gov/pubmed/18976728?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Genome-wide association analysis reveals putative Alzheimer's disease susceptibility loci in addition to APOE.


dbdate: 12/09/2008
author: Anney RJ
date: 10/24/2008
journal: Am J Med Genet B Neuropsychiatr Genet
trait: Attention deficit hyperactivity disorder and conduct disorder
initial_samplesize: 938 European ancestry trios
link:
http://www.ncbi.nlm.nih.gov/pubmed/18951430?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study.


dbdate: 12/01/2008
author: Johansson A
date: 10/24/2008
journal: Hum Mol Genet
trait: Height
initial_samplesize: 3,009 European ancestry individuals, 916 Dutch individuals
replication_samplesize: Up to 39,859 European ancestry individuals, Up to 1,148 African American individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/18952825?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Common variants in the JAZF1 gene associated with height identified by linkage and genome-wide association analysis.


dbdate: 12/09/2008
author: Comabella M
date: 10/22/2008
journal: PLoS One
trait: Multiple sclerosis
initial_samplesize: 242 European ancestry cases, 242 European ancestry controls
replication_samplesize: 553 European ancestry cases, 1,033 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18941528?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Identification of a novel risk locus for multiple sclerosis at 13q31.3 by a pooled genome-wide scan of 500,000 single nucleotide polymorphisms.


dbdate: 11/25/2008
author: Hillmer AM
date: 10/12/2008
journal: Nat Genet
study: Susceptibility variants for male-pattern baldness on chromosome 20p11.
trait: Male-pattern baldness
initial_samplesize: 296 European ancestry cases, 347 European ancestry controls
replication_samplesize: 319 European ancestry cases, 234 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18849994?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Richards JB
date: 10/12/2008
journal: Nat Genet
study: Male-pattern baldness susceptibility locus at 20p11.
trait: Male-pattern baldness
initial_samplesize: 578 European ancestry cases, 547 European ancestry controls
replication_samplesize: 1,351 European ancestry cases, 2,485 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18849991?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Stacey SN
date: 10/12/2008
journal: Nat Genet
trait: Basal cell carcinoma
initial_samplesize: 930 European ancestry cases, 33,117 European ancestry controls
replication_samplesize: 1,216 European ancestry cases, 2,844 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18849993?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Common variants on 1p36 and 1q42 are associated with cutaneous basal cell carcinoma but not with melanoma or pigmentation traits.


dbdate: 12/01/2008
author: Yuan X
date: 10/10/2008
journal: Am J Hum Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/18940312
trait: Liver enzyme levels
initial_samplesize: 7,751 European ancestry individuals
replication_samplesize: 1,005 European ancestry individuals, 3,669 Asian Indian ancestry individuals
study:
Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes.


dbdate: 11/25/2008
author: Grant SF
date: 10/07/2008
journal: Diabetes
study: Follow-up analysis of genome-wide association data identifies novel loci for type 1 diabetes.
trait: Type 1 diabetes
initial_samplesize: 563 European ancestry cases, 1,146 European ancestry controls, 483 European ancestry trios
replication_samplesize: 3,303 European ancestry cases, 4,673 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18840781?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 05/07/2009
author: Lesch KP
date: 10/07/2008
journal: J Neural Transm
trait: Attention deficit hyperactivity disorder
initial_samplesize: 343 European ancestry cases, 250 European ancestry controls, 54 controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18839057?ordinalpos=16&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Molecular genetics of adult ADHD: converging evidence from genome-wide association and extended pedigree linkage studies.


dbdate: 12/09/2008
author: Sonuga-Barke EJ
date: 10/07/2008
journal: Am J Med Genet B Neuropsychiatr Genet
trait: Attention deficit hyperactivity disorder symptoms (interaction)
initial_samplesize: 909 European ancestry trios
link:
http://www.ncbi.nlm.nih.gov/pubmed/18846501?ordinalpos=9&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Does parental expressed emotion moderate genetic effects in ADHD? An exploration using a genome wide association scan.


dbdate: 11/25/2008
author: Franke A
date: 10/05/2008
journal: Nat Genet
trait: Ulcerative colitis
initial_samplesize: 1,167 European ancestry cases, 777 European ancestry controls
replication_samplesize: 1,855 European ancestry cases, 3,091 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18836448?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility.


dbdate: 11/25/2008
author: Dehghan A
date: 10/01/2008
journal: Lancet
trait: Urate levels
initial_samplesize: 11,847 European ancestry individuals
replication_samplesize: 11,024 European ancestry individuals, 3,843 African American individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/18834626?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study.


dbdate: 12/09/2008
author: Gretarsdottir S
date: 10/01/2008
journal: Ann Neurol
study: Risk variants for atrial fibrillation on chromosome 4q25 associate with ischemic stroke.
trait: Stroke (ischemic)
initial_samplesize: 1,661 European ancestry cases, 10,815 European ancestry controls
replication_samplesize: 4,576 European ancestry cases, 19,343 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18991354?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 01/13/2010
author: Heid IM
date: 10/01/2008
journal: Circ Cardiovasc Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/20031538
trait: HDL cholesterol
initial_samplesize: Up to 4,274 European ancestry individuals
replication_samplesize: Up to 15,873 European ancestry individuals
study:
Genome-wide association analysis of high-density lipoprotein cholesterol in the population-based KORA study sheds new light on intergenic regions.


dbdate: 11/25/2008
author: Mushiroda T
date: 10/01/2008
journal: J Med Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/18835860
trait: Idiopathic pulmonary fibrosis
initial_samplesize: 159 Japanese ancestry cases, 934 Japanese ancestry controls
replication_samplesize: 83 Japanese ancestry cases, 535 Japanese ancestry controls
study:
A genome-wide association study identifies an association of a common variant in TERT with susceptibility to idiopathic pulmonary fibrosis.


dbdate: 11/25/2008
author: Abraham R
date: 09/29/2008
journal: BMC Med Genomics
study: A genome-wide association study for late-onset Alzheimer's disease using DNA pooling.
trait: Alzheimer's disease
initial_samplesize: 1,082 European ancestry cases, 1,239 European ancestry controls
replication_samplesize: 1,400 controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18823527?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Miyagawa T
date: 09/28/2008
journal: Nat Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/18820697
study: Variant between CPT1B and CHKB associated with susceptibility to narcolepsy.
trait: Narcolepsy
initial_samplesize: 222 Japanese ancestry cases, 389 Japanese ancestry controls
replication_samplesize:
274 East Asian ancestry cases, 499 East Asian ancestry controls, 388 European ancestry cases, 397 European ancestry controls, 86 African American cases, 98 African American controls


dbdate: 11/25/2008
author: Mick E
date: 09/26/2008
journal: Am J Med Genet B Neuropsychiatr Genet
trait: Attention deficit hyperactivity disorder
initial_samplesize: 105 European ancestry cases, 34 Hispanic cases, 26 African American cases, 22 Other ancestry cases
link:
http://www.ncbi.nlm.nih.gov/pubmed/18821564?ordinalpos=&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.SmartSearch&log$=citationsensor

study:
Genome-wide association study of response to methylphenidate in 187 children with attention-deficit/hyperactivity disorder.


dbdate: 12/09/2008
author: Burkhardt R
date: 09/18/2008
journal: Arterioscler Thromb Vasc Biol
link: http://www.ncbi.nlm.nih.gov/pubmed/18802019
trait: LDL cholesterol
initial_samplesize: 2,346 Micronesian ancestry individuals
study:
Common SNPs in HMGCR in micronesians and whites associated with LDL-cholesterol levels affect alternative splicing of exon13.


dbdate: 11/25/2008
author: Liu P
date: 09/17/2008
journal: J Natl Cancer Inst
study: Familial aggregation of common sequence variants on 15q24-25.1 in lung cancer.
trait: Lung cancer
initial_samplesize: 194 European ancestry cases, 219 European ancestry controls
replication_samplesize: 3,878 cases, 4,831 controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18780872?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Kiemeney LA
date: 09/14/2008
journal: Nat Genet
study: Sequence variant on 8q24 confers susceptibility to urinary bladder cancer.
trait: Urinary bladder cancer
initial_samplesize: 1,803 European ancestry cases, 34,336 European ancestry controls
replication_samplesize: 2,165 European ancestry cases, 3,800 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18794855?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Raychaudhuri S
date: 09/14/2008
journal: Nat Genet
study: Common variants at CD40 and other loci confer risk of rheumatoid arthritis.
trait: Rheumatoid arthritis
initial_samplesize: 3,393 European ancestry cases, 12,460 European ancestry controls
replication_samplesize: 3,929 European ancestry cases, 5,807 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18794853?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Liu YZ
date: 09/08/2008
journal: PLoS One
trait: Hip bone size
initial_samplesize: 501 European ancestry women, 499 European ancestry men
replication_samplesize: 1,216 European ancestry women
link:
http://www.ncbi.nlm.nih.gov/pubmed/18776929?ordinalpos=8&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Identification of PLCL1 gene for hip bone size variation in females in a genome-wide association study.


dbdate: 11/25/2008
author: Hazra A
date: 09/07/2008
journal: Nat Genet
study: Common variants of FUT2 are associated with plasma vitamin B12 levels.
trait: Vitamin B12 levels
initial_samplesize: 1,658 European ancestry women
replication_samplesize: 1,059 European ancestry women
link:
http://www.ncbi.nlm.nih.gov/pubmed/18776911?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: McArdle PF
date: 09/01/2008
journal: Arthritis Rheum
trait: Uric acid levels
initial_samplesize: 408 Old Order Amish women, 460 Old Order Amish men
replication_samplesize: Framingham Heart Study (Sample size NR)
link:
http://www.ncbi.nlm.nih.gov/pubmed/18759275?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Association of a common nonsynonymous variant in GLUT9 with serum uric acid levels in old order amish.


dbdate: 11/25/2008
author: van den Oord EJ
date: 09/01/2008
journal: Arch Gen Psychiatry
trait: Neuroticism
initial_samplesize: 1,227 European ancestry individuals
replication_samplesize: 1,880 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/18762592?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
Genomewide association analysis followed by a replication study implicates a novel candidate gene for neuroticism.


dbdate: 11/25/2008
author: Di Bernardo MC
date: 08/31/2008
journal: Nat Genet
trait: Chronic lymphocytic leukemia
initial_samplesize: 505 European ancestry cases, 1,438 European ancestry controls
replication_samplesize: 1,024 European ancestry cases, 1,677 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18758461?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia.


dbdate: 11/25/2008
author: Kugathasan S
date: 08/31/2008
journal: Nat Genet
study: Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease.
trait: Inflammatory bowel disease
initial_samplesize: 1,011 European ancestry cases, 4,250 European ancestry controls
replication_samplesize: 1,922 European ancestry cases, 14,124 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18758464?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Weidinger S
date: 08/22/2008
journal: PLoS Genet
study: Genome-wide scan on total serum IgE levels identifies FCER1A as novel susceptibility locus.
trait: IgE levels
initial_samplesize: 1,530 European ancesrty individuals
replication_samplesize: 9,769 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/18846228?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Ferreira MA
date: 08/17/2008
journal: Nat Genet
trait: Bipolar disorder
initial_samplesize: 4,387 European ancestry cases, 6,209 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18711365?ordinalpos=4&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.


dbdate: 04/10/2009
author: Unoki H
date: 08/17/2008
journal: Nat Genet
trait: Type 2 diabetes
initial_samplesize: 194 Japanese ancestry cases, 1,558 Japanese ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18711366?ordinalpos=4&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

study:
SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations.

replication_samplesize:
5,324 East Asian ancestry cases, 7,037 East Asian ancestry controls, 4,085 European ancestry cases, 5,302 European ancestry controls


dbdate: 04/03/2009
author: Yasuda K
date: 08/17/2008
journal: Nat Genet
study: Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus.
trait: Type 2 diabetes
initial_samplesize: 187 Japanese cases, 1,504 Japanese controls
replication_samplesize: 6,552 Asian cases, 6,621 Asian controls, 2,830 cases, 3,740 controls (Swedish)
link:
http://www.ncbi.nlm.nih.gov/pubmed/18711367?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Julia A
date: 08/01/2008
journal: Arthritis Rheum
trait: Rheumatoid arthritis
initial_samplesize: 400 European ancestry cases, 400 European ancestry controls
replication_samplesize: 410 European ancestry cases, 394 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18668548?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
Genome-wide association study of rheumatoid arthritis in the Spanish population: KLF12 as a risk locus for rheumatoid arthritis susceptibility.


dbdate: 11/25/2008
author: O'Donovan MC
date: 07/30/2008
journal: Nat Genet
study: Identification of loci associated with schizophrenia by genome-wide association and follow-up.
trait: Schizophrenia
initial_samplesize: 479 European ancestry cases, 2,937 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18677311?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

replication_samplesize:
4,143 European ancestry cases, 6,515 European ancestry controls, 1,782 East Asian ancestry cases, 1,865 East Asian ancestry controls, 741 Other ancestry cases, 1,517 Other ancestry controls


dbdate: 11/25/2008
author: Schormair B
date: 07/27/2008
journal: Nat Genet
study: PTPRD (protein tyrosine phosphatase receptor type delta) is associated with restless legs syndrome.
trait: Restless legs syndrome
initial_samplesize: 628 European ancestry cases, 1,644 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18660810?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

replication_samplesize:
1,550 European ancestry cases, 2,269 European ancestry controls, 285 French Canadian founder cases, 842 French Canadian founder controls


dbdate: 11/25/2008
author: Link E
date: 07/23/2008
journal: N Engl J Med
study: SLCO1B1 variants and statin-induced myopathy--a genomewide study.
trait: Response to statin therapy
initial_samplesize: 85 European ancestry cases, 90 European ancestry controls
replication_samplesize: 21 European ancestry cases, 16,643 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18650507?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Franke A
date: 07/21/2008
journal: Gastroenterology
trait: Crohn's disease and sarcoidosis (combined)
link:
http://www.ncbi.nlm.nih.gov/pubmed/18723019?ordinalpos=6&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
Genome-wide association analysis in sarcoidosis and Crohn's disease unravels a common susceptibility locus on 10p12.2.

initial_samplesize:
382 European ancestry Crohn's disease cases, 398 European ancestry Sarcoidosis cases, 394 European ancestry controls

replication_samplesize:
660 European ancestry Crohn's disease cases, 657 European ancestry Sarcoidosis cases, 1,091 European ancestry controls


dbdate: 11/25/2008
author: Liu C
date: 07/10/2008
journal: Mol Med
trait: Response to TNF antagonist treatment
initial_samplesize: 89 European ancestry cases
link:
http://www.ncbi.nlm.nih.gov/pubmed/18615156?ordinalpos=6&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
Genome-wide association scan identifies candidate polymorphisms associated with differential response to anti-TNF treatment in rheumatoid arthritis.


dbdate: 11/25/2008
author: Pare G
date: 07/04/2008
journal: PLoS Genet
trait: Soluble ICAM-1
initial_samplesize: 4,570 European ancestry women
replication_samplesize: 2,008 European ancestry women
link:
http://www.ncbi.nlm.nih.gov/pubmed/18604267?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
Novel association of ABO histo-blood group antigen with soluble ICAM-1: results of a genome-wide association study of 6,578 women.


dbdate: 11/25/2008
author: Sarasquete ME
date: 07/01/2008
journal: Blood
trait: Osteonecrosis of the jaw
initial_samplesize: 22 European ancestry cases, 65 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18594024?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
Bisphosphonate-related osteonecrosis of the jaw is associated with polymorphisms of the cytochrome P450 CYP2C8 in multiple myeloma: a genome-wide single nucleotide polymorphism analysis.


dbdate: 11/25/2008
author: Barrett JC
date: 06/29/2008
journal: Nat Genet
study: Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.
trait: Crohn's disease
initial_samplesize: 3,230 European ancestry cases, 4,829 European ancestry controls
replication_samplesize: 1,339 European ancestry trios, 2,325 European ancestry cases, 1,809 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18587394?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Behrens EM
date: 06/24/2008
journal: Arthritis Rheum
study: Association of the TRAF1-C5 locus on chromosome 9 with juvenile idiopathic arthritis.
trait: Arthritis (juvenile idiopathic)
initial_samplesize: 67 European ancestry cases, 1,952 European ancestry controls, 63 cases
link:
http://www.ncbi.nlm.nih.gov/pubmed/18576341?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Bouatia-Naji N
date: 06/19/2008
journal: Science
study: A polymorphism within the G6PC2 gene is associated with fasting plasma glucose levels.
trait: Fasting plasma glucose
initial_samplesize: 654 European ancestry individuals
replication_samplesize: 9,353 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/18451265?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Cooper GM
date: 06/05/2008
journal: Blood
study: A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose.
trait: Warfarin maintenance dose
initial_samplesize: 181 European ancestry individuals
replication_samplesize: 374 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/18535201?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Chen WM
date: 06/04/2008
journal: J Clin Invest
study: Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels.
trait: Fasting plasma glucose
initial_samplesize: 5,088 European ancestry individuals
replication_samplesize: 18,436 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/18521185?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Volpi S
date: 06/03/2008
journal: Mol Psychiatry
trait: Response to iloperidone treatment (QT prolongation)
link:
http://www.ncbi.nlm.nih.gov/pubmed/18521091?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
Whole genome association study identifies polymorphisms associated with QT prolongation during iloperidone treatment of schizophrenia.

initial_samplesize:
91 African American Schizophrenia cases, 69 European ancestry Schizophrenia cases, 16 Asian unspecified Schizophrenia cases, 7 Other ancestry Schizophrenia cases


dbdate: 11/25/2008
author: Brown KM
date: 05/18/2008
journal: Nat Genet
study: Common sequence variants on 20q11.22 confer melanoma susceptibility.
trait: Melanoma
initial_samplesize: 864 European ancestry cases, 864 European ancestry controls
replication_samplesize: 1,230 European ancestry cases, 1,251 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18488026?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Sulem P
date: 05/18/2008
journal: Nat Genet
study: Two newly identified genetic determinants of pigmentation in Europeans.
trait: Blond vs. brown hair color
initial_samplesize: 5,130 European ancestry individuals
replication_samplesize: 3,330 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/18488028?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Han J
date: 05/16/2008
journal: PLoS Genet
trait: Black vs. blond hair color
initial_samplesize: 2,287 European ancestry women
replication_samplesize: 8,465 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/18483556?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation.


dbdate: 11/25/2008
author: Maris JM
date: 05/09/2008
journal: N Engl J Med
study: Chromosome 6p22 locus associated with clinically aggressive neuroblastoma.
trait: Neuroblastoma
initial_samplesize: 1,032 European ancestry cases, 2,043 European ancestry controls
replication_samplesize: 720 European ancestry cases, 2,128 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18463370?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Melzer D
date: 05/09/2008
journal: PLoS Genet
study: A genome-wide association study identifies protein quantitative trait loci (pQTLs).
trait: Protein quantitative trait loci
initial_samplesize: 1,200 European ancestry individuals
replication_samplesize: up to 4,590 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/18464913?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Valdes AM
date: 05/08/2008
journal: Am J Hum Genet
trait: Knee osteoarthritis
initial_samplesize: 357 European ancestry cases, 285 European ancestry controls
replication_samplesize: 1,177 European ancestry cases, 2,372 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18471798?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
Genome-wide association scan identifies a prostaglandin-endoperoxide synthase 2 variant involved in risk of knee osteoarthritis.


dbdate: 11/25/2008
author: Loos RJ
date: 05/04/2008
journal: Nat Genet
study: Common variants near MC4R are associated with fat mass, weight and risk of obesity.
trait: Body mass index
initial_samplesize: 16,876 European ancestry adults
replication_samplesize: 60,352 European ancestry adults, 5,988 European ancestry children
link:
http://www.ncbi.nlm.nih.gov/pubmed/18454148?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Richards JB
date: 04/29/2008
journal: Lancet
study: Bone mineral density, osteoporosis, and osteoporotic fractures: a genome-wide association study.
trait: Bone mineral density
initial_samplesize: 2,094 European ancestry women
replication_samplesize: 6,463 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/18455228?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Styrkarsdottir U
date: 04/29/2008
journal: N Engl J Med
study: Multiple genetic loci for bone mineral density and fractures.
trait: Bone mineral density (hip)
initial_samplesize: 5,861 European ancestry individuals
replication_samplesize: 7,925 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/18445777?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Reiner AP
date: 04/24/2008
journal: Am J Hum Genet
trait: C-reactive protein
initial_samplesize: 909 European ancestry individuals
replication_samplesize: 5,106 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/18439552?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein.


dbdate: 11/25/2008
author: Ridker PM
date: 04/24/2008
journal: Am J Hum Genet
trait: C-reactive protein
initial_samplesize: 6,345 European ancestry women
link:
http://www.ncbi.nlm.nih.gov/pubmed/18439548?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
Loci related to metabolic-syndrome pathways including LEPR,HNF1A, IL6R, and GCKR associate with plasma C-reactive protein: the Women's Genome Health Study.


dbdate: 11/25/2008
author: Ober C
date: 04/09/2008
journal: N Engl J Med
study: Effect of variation in CHI3L1 on serum YKL-40 level, risk of asthma, and lung function.
trait: YKL-40 levels
initial_samplesize: 632 Hutterite individuals
replication_samplesize: 443 European ancestry cases, 491 European ancestry controls, 206 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/18403759?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Gudbjartsson DF
date: 04/06/2008
journal: Nat Genet
study: Many sequence variants affecting diversity of adult human height.
trait: Height
initial_samplesize: 30,968 European ancestry individuals
replication_samplesize: 8,541 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/18391951?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Lettre G
date: 04/06/2008
journal: Nat Genet
trait: Height
initial_samplesize: 15,821 European ancestry individuals
replication_samplesize: Up to 17,801 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/18391950?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
Identification of ten loci associated with height highlights new biological pathways in human growth.


dbdate: 11/25/2008
author: Weedon MN
date: 04/06/2008
journal: Nat Genet
study: Genome-wide association analysis identifies 20 loci that influence adult height.
trait: Height
initial_samplesize: 13,665 European ancestry individuals
replication_samplesize: 16,482 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/18391952?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Liu Y
date: 04/04/2008
journal: PLoS Genet
study: A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci.
trait: Psoriasis
initial_samplesize: 218 European ancestry cases, 519 European ancestry controls
replication_samplesize: 1,153 European ancestry cases, 1,217 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18369459?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Amos CI
date: 04/03/2008
journal: Nat Genet
trait: Lung cancer
initial_samplesize: 1,154 European ancestry cases, 1,137 European ancestry controls
replication_samplesize: 2,724 European ancestry cases, 3,694 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18385676?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1.


dbdate: 11/25/2008
author: Hung RJ
date: 04/03/2008
journal: Nature
trait: Lung cancer
initial_samplesize: 1,926 European ance other ancestry cases, 2,522 European and other ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18385738?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25.

replication_samplesize:
332 European ancestry cases, 462 European ancestry controls, 2,181 European and other ancestry cases, 4,290 European and other ancestry controls


dbdate: 11/25/2008
author: Thorgeirsson TE
date: 04/03/2008
journal: Nature
study: A variant associated with nicotine dependence, lung cancer and peripheral arterial disease.
trait: Nicotine dependence
initial_samplesize: 10,995 European ancestry individuals
replication_samplesize: 4,848 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/18385739?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Tenesa A
date: 03/30/2008
journal: Nat Genet
trait: Colorectal cancer
initial_samplesize: 981 European ancestry cases, 1,002 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18372901?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21.

replication_samplesize:
10,287 European ancestry cases, 10,401 European ancestry controls, 4,400 Japanese ancestry cases, 3,179 Japanese ancestry controls, 1,789 Other ancestry cases, 1,771 Other ancestry controls


dbdate: 11/25/2008
author: Tomlinson IP
date: 03/30/2008
journal: Nat Genet
trait: Colorectal cancer
initial_samplesize: 922 European ancestry cases, 927 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18372905?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3.

replication_samplesize:
17,089 European ancestry cases, 16,862 European ancestry controls, 783 Other ancestry cases, 664 Other ancestry controls


dbdate: 11/25/2008
author: Zeggini E
date: 03/30/2008
journal: Nat Genet
trait: Type 2 diabetes
initial_samplesize: 4,549 European ancestry cases, 5,579 European ancestry controls
replication_samplesize: 24,194 European ancestry cases, 55,598 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18372903?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes.


dbdate: 11/25/2008
author: Capon F
date: 03/25/2008
journal: Hum Mol Genet
study: Identification of ZNF313/RNF114 as a novel psoriasis susceptibility gene.
trait: Psoriasis
initial_samplesize: 318 European ancestry cases, 288 European ancestry controls
replication_samplesize: 2,361 European ancestry cases, 1,927 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18364390?ordinalpos=12&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Sullivan PF
date: 03/18/2008
journal: Mol Psychiatry
study: Genomewide association for schizophrenia in the CATIE study: results of stage 1.
trait: Schizophrenia
link:
http://www.ncbi.nlm.nih.gov/pubmed/18347602?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

initial_samplesize:
417 European ancestry cases, 411 European ancestry controls, 217 African American cases, 219 African American controls, 104 cases of American Indian, Asian unspecified, Pacific Islander, or Hispanic/Latino ancestry, 103 controls of American Indian, Asian unspecified, Pacific Islander, or Hispanic/Latino ancestry


dbdate: 11/25/2008
author: Gold B
date: 03/11/2008
journal: Proc Natl Acad Sci U S A
link: http://www.ncbi.nlm.nih.gov/pubmed/18326623
study: Genome-wide association study provides evidence for a breast cancer risk locus at 6q22.33.
trait: Breast cancer
initial_samplesize:
249 Ashkenazi Jewish ancestry non-BRCA1/2 carriers cases, 299 Ashkenazi Jewish ancestry non-BRCA1/2 carriers controls

replication_samplesize:
1,193 Ashkenazi Jewish ancestry non-BRCA1/2 carriers  cases,1,166 Ashkenazi Jewish ancestry non-BRCA1/2 carriers controls


dbdate: 11/25/2008
author: Kirov G
date: 03/11/2008
journal: Mol Psychiatry
study: A genome-wide association study in 574 schizophrenia trios using DNA pooling.
trait: Schizophrenia
initial_samplesize: 574 European ancestry trios, 605 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18332876?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Doring A
date: 03/09/2008
journal: Nat Genet
study: SLC2A9 influences uric acid concentrations with pronounced sex-specific effects.
trait: Urate levels
initial_samplesize: 1,644 European ancestry individuals
replication_samplesize: 9,947 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/18327256?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Vitart V
date: 03/09/2008
journal: Nat Genet
trait: Urate levels
initial_samplesize: 794 European ancestry individuals
replication_samplesize: 706 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/18327257?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout.


dbdate: 11/25/2008
author: Hunt KA
date: 03/02/2008
journal: Nat Genet
study: Newly identified genetic risk variants for celiac disease related to the immune response.
trait: Celiac disease
initial_samplesize: 767 European ancestry cases, 1,422 European ancestry controls
replication_samplesize: 1,643 European ancestry cases, 3,406 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18311140?ordinalpos=7&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Shifman S
date: 02/15/2008
journal: PLoS Genet
trait: Schizophrenia
initial_samplesize: 660 Ashkenazi Jewish cases, 2,271 Ashkenazi Jewish controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18282107?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
Genome-wide association identifies a common variant in the reelin gene that increases the risk of schizophrenia only in women.

replication_samplesize:
1,859 European ancestry cases, 3,943 European ancestry controls, 759 Ashkenazi Jewish cases, 3,389 Ashkenazi Jewish controls, 415 Han Chinese ancestry cases, 458 Han Chinese ancestry controls


dbdate: 11/25/2008
author: Eeles RA
date: 02/10/2008
journal: Nat Genet
study: Multiple newly identified loci associated with prostate cancer susceptibility.
trait: Prostate cancer
initial_samplesize: 1,854 European ancestry cases, 1,894 European ancestry controls
replication_samplesize: 3,268 European ancestry cases, 3,366 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18264097?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Gudmundsson J
date: 02/10/2008
journal: Nat Genet
study: Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer.
trait: Prostate cancer
initial_samplesize: 1,854 European ancestry cases, 21,372 European ancestry controls
replication_samplesize: 8,239 European ancestry cases, 7,590 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18264098?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Thomas G
date: 02/10/2008
journal: Nat Genet
study: Multiple loci identified in a genome-wide association study of prostate cancer.
trait: Prostate cancer
initial_samplesize: 1,172 European ancestry cases, 1,157 European ancestry controls
replication_samplesize: 3,941 European ancestry cases, 3,964 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18264096?ordinalpos=6&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Sandhu MS
date: 02/09/2008
journal: Lancet
study: LDL-cholesterol concentrations: a genome-wide association study.
trait: LDL cholesterol
initial_samplesize: 11,685 European ancestry individuals
replication_samplesize: Up to 4,979 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/18262040?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Uda M
date: 02/05/2008
journal: Proc Natl Acad Sci U S A
trait: Fetal hemoglobin levels
initial_samplesize: 4,305 European ancestry individuals
replication_samplesize: 521 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/18245381?rdinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of beta-thalassemia.


dbdate: 11/25/2008
author: Kong A
date: 02/02/2008
journal: Science
study: Sequence variants in the RNF212 gene associate with genome-wide recombination rate.
trait: Recombination rate (females)
initial_samplesize: 1,702 women
replication_samplesize: 1,663 women
link:
http://www.ncbi.nlm.nih.gov/pubmed/18239089?ordinalpos=7&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Kayser M
date: 01/24/2008
journal: Am J Hum Genet
trait: Iris color
initial_samplesize: 925 Erasmus Ruchpen individuals, 481 European ancestry women
replication_samplesize: 5,575 European ancestry individuals, 1,292 Erasmus Ruchpen individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/18252221?ordinalpos=4&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
Three genome-wide association studies and a linkage analysis identify HERC2 as a human iris color gene.


dbdate: 11/25/2008
author: Harley JB
date: 01/20/2008
journal: Nat Genet
trait: Systemic lupus erythematosus
initial_samplesize: 720 European ancestry female cases, 2,337 European ancestry female controls
replication_samplesize: 1,846 European ancestry female cases, 1,825 European ancestry female controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18204446?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.


dbdate: 11/25/2008
author: Hom G
date: 01/20/2008
journal: N Engl J Med
study: Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX.
trait: Systemic lupus erythematosus
initial_samplesize: 1,311 European ancestry cases, 3,340 European ancestry controls
replication_samplesize: 793 European ancestry cases, 857 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18204098?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Kozyrev SV
date: 01/20/2008
journal: Nat Genet
study: Functional variants in the B-cell gene BANK1 are associated with systemic lupus erythematosus.
trait: Systemic lupus erythematosus
initial_samplesize: 279 European ancestry cases, 515 European ancestry controls
replication_samplesize: 1,757 European ancestry cases, 1,540 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18204447?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Hakonarson H
date: 01/15/2008
journal: Diabetes
trait: Type 1 diabetes
initial_samplesize: 467 European ancestry trios, 561 European ancestry cases, 1,143 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18198356?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
A novel susceptibility locus for type 1 diabetes on Chr12q13 identified by a genome-wide association study.

replication_samplesize:
946 European ancestry cases and 1,098 European ancestry controls from 549 families, 364 European ancestry trios


dbdate: 11/25/2008
author: Kathiresan S
date: 01/13/2008
journal: Nat Genet
trait: HDL cholesterol
initial_samplesize: 2,758 individuals
replication_samplesize: 18,544 individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/18193044?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.


dbdate: 11/25/2008
author: Kooner JS
date: 01/13/2008
journal: Nat Genet
study: Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides.
trait: Triglycerides
initial_samplesize: 1,005 European ancestry males, 1,006 Indian Asian ancestry males
link:
http://www.ncbi.nlm.nih.gov/pubmed/18193046?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

replication_samplesize:
6,827 European ancestry individuals, 2,528 Mexican ancestry individuals, 1,181 Indian Asian ancestry women


dbdate: 11/25/2008
author: Sanna S
date: 01/13/2008
journal: Nat Genet
study: Common variants in the GDF5-UQCC region are associated with variation in human height.
trait: Height
initial_samplesize: 1,084 European ancestry cases, 1,287 European ancestry controls, 4,298 European individuals
replication_samplesize: 23,684 European ancestry individuals, 3,860 African American individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/18193045?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Willer CJ
date: 01/13/2008
journal: Nat Genet
study: Newly identified loci that influence lipid concentrations and risk of coronary artery disease.
trait: HDL cholesterol
initial_samplesize: 8,656 European ancestry individuals
replication_samplesize: 11,437 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/18193043?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Wallace C
date: 01/10/2008
journal: Am J Hum Genet
trait: LDL cholesterol
initial_samplesize: 1,955 European ancestry hypertensive individuals
replication_samplesize: 2,033 European ancestry individuals from 519 families; 1,461 European ancestry twins
link:
http://www.ncbi.nlm.nih.gov/pubmed/18179892?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia.


dbdate: 11/25/2008
author: Hinney A
date: 12/26/2007
journal: PLoS One
trait: Obesity (early onset extreme)
initial_samplesize: 487 European ancestry cases, 442 European ancestry controls
replication_samplesize: 2,269 European ancestry individuals from 644 families
link:
http://www.ncbi.nlm.nih.gov/pubmed/18159244?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
Genome wide association (GWA) study for early onset extreme obesity supports the role of fat mass and obesity associated gene (FTO) variants.


dbdate: 11/25/2008
author: van Es MA
date: 12/16/2007
journal: Nat Genet
study: Genetic variation in DPP6 is associated with susceptibility to amyotrophic lateral sclerosis.
trait: Amyotrophic lateral sclerosis
initial_samplesize: 737 European ancestry cases, 721 European ancestry controls
replication_samplesize: 1,030 European ancestry cases, 1,195 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18084291?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Cronin S
date: 12/07/2007
journal: Hum Mol Genet
study: A genome-wide association study of sporadic ALS in a homogenous Irish population.
trait: Amyotrophic lateral sclerosis
initial_samplesize: 221 Genetically Homogenous Irish cases, 211 Genetically Homogenous Irish controls
replication_samplesize: 737 European ancestry cases, 721 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18057069?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Suzuki S
date: 11/17/2007
journal: Pharmacogenet Genomics
trait: Coronary spasm
initial_samplesize: 50 Japanese ancestry female cases, 50 Japanese ancestry female controls
replication_samplesize: 151 Japanese ancestry female cases, 160 Japanese ancestry female controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/18075462?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
A novel genetic marker for coronary spasm in women from a genome-wide single nucleotide polymorphism analysis.


dbdate: 11/25/2008
author: Li H
date: 11/12/2007
journal: Arch Neurol
study: Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease.
trait: Alzheimer's disease
initial_samplesize: 753 European ancestry cases, 736 European ancestry controls
replication_samplesize: 418 European ancestry cases, 249 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17998437?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Plenge RM
date: 11/04/2007
journal: Nat Genet
study: Two independent alleles at 6q23 associated with risk of rheumatoid arthritis.
trait: Rheumatoid arthritis
initial_samplesize: 397 European ancestry cases, 1,211 Other ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17982456?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

replication_samplesize:
1,408 Other ancestry cases, 2,426 Other ancestry controls, 875 European ancestry cases, 832 European ancestry controls


dbdate: 11/25/2008
author: Webster JA
date: 11/01/2007
journal: Neurodegener Dis
study: Sorl1 as an Alzheimer's disease predisposition gene?
trait: Alzheimer's disease
initial_samplesize: 664 cases, 422 controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17975299?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Sulem P
date: 10/21/2007
journal: Nat Genet
study: Genetic determinants of hair, eye and skin pigmentation in Europeans.
trait: Blond vs. brown hair color
initial_samplesize: 2,986 European ancestry individuals
replication_samplesize: 3,932 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/17952075?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Stokowski RP
date: 10/15/2007
journal: Am J Hum Genet
study: A genomewide association study of skin pigmentation in a South Asian population.
trait: Skin pigmentation
initial_samplesize: 363 South Asian ancestry low maxL* individuals, 374 South Asian ancestry high maxL* individuals
replication_samplesize: 116 South Asian ancestry low maxL* individuals, 115 South Asian ancestry high maxL* individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/17999355?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Broderick P
date: 10/14/2007
journal: Nat Genet
trait: Colorectal cancer
initial_samplesize: 930 European ancestry cases, 960 European ancestry controls
replication_samplesize: 7,473 European ancestry cases, 5,984 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17934461?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk.


dbdate: 11/25/2008
author: Benjamin EJ
date: 09/19/2007
journal: BMC Med Genet
study: Genome-wide association with select biomarker traits in the Framingham Heart Study.
trait: Select biomarker traits
initial_samplesize: 1,012 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/17903293?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Fox CS
date: 09/19/2007
journal: BMC Med Genet
trait: Body mass index
initial_samplesize: 1,341 European ancestry individuals from 310 families
link:
http://www.ncbi.nlm.nih.gov/pubmed/17903300?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
Genome-wide association to body mass index and waist circumference: the Framingham Heart Study 100K project.


dbdate: 08/01/2014
author: Gottlieb DJ
date: 09/19/2007
journal: BMC Med Genet
study: Genome-wide association of sleep and circadian phenotypes.
trait: Sleep-related phenotypes
initial_samplesize: up to 738 individuals from 203 families
link:
http://www.ncbi.nlm.nih.gov/pubmed/17903308?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Hwang SJ
date: 09/19/2007
journal: BMC Med Genet
trait: Cystatin C
initial_samplesize: 981 individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/17903292?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
A genome-wide association for kidney function and endocrine-related traits in the NHLBI's Framingham Heart Study.


dbdate: 11/25/2008
author: Kiel DP
date: 09/19/2007
journal: BMC Med Genet
study: Genome-wide association with bone mass and geometry in the Framingham Heart Study.
trait: Bone mineral density
initial_samplesize: Up to 1,141 individuals from 241 families
link:
http://www.ncbi.nlm.nih.gov/pubmed/17903296?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Larson MG
date: 09/19/2007
journal: BMC Med Genet
study: Framingham Heart Study 100K project: genome-wide associations for cardiovascular disease outcomes.
trait: Atrial fibrillation
initial_samplesize: 151 Other ancestry cases and 1,190 Other ancestry controls from 310 families
link:
http://www.ncbi.nlm.nih.gov/pubmed/17903304?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Levy D
date: 09/19/2007
journal: BMC Med Genet
trait: Blood pressure
initial_samplesize: Up to 1,327 Other ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/17903302?ordinalpos=7&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
Framingham Heart Study 100K Project: genome-wide associations for blood pressure and arterial stiffness.


dbdate: 11/25/2008
author: Lunetta KL
date: 09/19/2007
journal: BMC Med Genet
trait: Aging traits
initial_samplesize: 1,345 individuals from 330 families
link:
http://www.ncbi.nlm.nih.gov/pubmed/17903295?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study.


dbdate: 11/25/2008
author: Meigs JB
date: 09/19/2007
journal: BMC Med Genet
study: Genome-wide association with diabetes-related traits in the Framingham Heart Study.
trait: Diabetes (incident)
initial_samplesize: 91 cases, 1,083 controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17903298?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Murabito JM
date: 09/19/2007
journal: BMC Med Genet
trait: Breast cancer
initial_samplesize: 58 cases, 665 controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17903305?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
A genome-wide association study of breast and prostate cancer in the NHLBI's Framingham Heart Study.


dbdate: 11/25/2008
author: Newton-Cheh C
date: 09/19/2007
journal: BMC Med Genet
trait: Electrocardiographic traits
initial_samplesize: 1,951 European ancestry individuals from 355 families
link:
http://www.ncbi.nlm.nih.gov/pubmed/17903306?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
Genome-wide association study of electrocardiographic and heart rate variability traits: the Framingham Heart Study.


dbdate: 11/25/2008
author: O'Donnell CJ
date: 09/19/2007
journal: BMC Med Genet
trait: Coronary artery calcification
initial_samplesize: Up to 678 individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/17903303?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
Genome-wide association study for subclinical atherosclerosis in major arterial territories in the NHLBI's Framingham Heart Study.


dbdate: 11/25/2008
author: Seshadri S
date: 09/19/2007
journal: BMC Med Genet
trait: Cognitive test performance
initial_samplesize: 694 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/17903297?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
Genetic correlates of brain aging on MRI and cognitive test measures: a genome-wide association and linkage analysis in the Framingham Study.


dbdate: 11/25/2008
author: Vasan RS
date: 09/19/2007
journal: BMC Med Genet
trait: Echocardiographic traits
initial_samplesize: Up to 1,238 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/17903301?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
Genome-wide association of echocardiographic dimensions, brachial artery endothelial function and treadmill exercise responses in the Framingham Heart Study.


dbdate: 11/25/2008
author: Yang Q
date: 09/19/2007
journal: BMC Med Genet
trait: Factor VII
initial_samplesize: 886 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/17903294?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study.


dbdate: 11/25/2008
author: van Es MA
date: 09/07/2007
journal: Lancet Neurol
trait: Amyotrophic lateral sclerosis
initial_samplesize: 461 European ancestry cases, 450 European ancestry controls
replication_samplesize: 876 European ancestry cases, 906 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17827064?ordinalpos=13&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
ITPR2 as a susceptibility gene in sporadic amyotrophic lateral sclerosis: a genome-wide association study.


dbdate: 11/25/2008
author: Plenge RM
date: 09/05/2007
journal: N Engl J Med
study: TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study.
trait: Rheumatoid arthritis
initial_samplesize: 1,522 European ancestry cases, 1,850 European ancestry controls
replication_samplesize: 1,053 European ancestry cases, 1,858 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17804836?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Raelson JV
date: 09/05/2007
journal: Proc Natl Acad Sci U S A
trait: Crohn's disease
initial_samplesize: 382 French Canadian founder trios
replication_samplesize: 750 European ancestry cases, 828 European ancestry controls, 521 Europeann ancestry trios
link:
http://www.ncbi.nlm.nih.gov/pubmed/17804789?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci.


dbdate: 11/25/2008
author: Menzel S
date: 09/02/2007
journal: Nat Genet
trait: F-cell distribution
initial_samplesize: 179 European ancestry individuals
replication_samplesize: 90 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/17767159?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
A QTL influencing F cell production maps to a gene encoding a zinc-finger protein on chromosome 2p15.


dbdate: 11/25/2008
author: Weedon MN
date: 09/02/2007
journal: Nat Genet
study: A common variant of HMGA2 is associated with adult and childhood height in the general population.
trait: Height
initial_samplesize: 4,921 European ancestry individuals
replication_samplesize: 19,064 European ancestry adults, 6,827 European ancestry children
link:
http://www.ncbi.nlm.nih.gov/pubmed/17767157?ordinalpos=7&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Thorleifsson G
date: 08/09/2007
journal: Science
study: Common sequence variants in the LOXL1 gene confer susceptibility to exfoliation glaucoma.
trait: Glaucoma (exfoliation)
initial_samplesize: 75 European ancestry cases, 14,474 European ancestry controls
replication_samplesize: 199 European ancestry cases, 198 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17690259?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Franke A
date: 08/08/2007
journal: PLoS One
study: Systematic association mapping identifies NELL1 as a novel IBD disease gene.
trait: Crohn's disease
initial_samplesize: 393 European ancestry cases, 399 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17684544?ordinalpos=6&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

replication_samplesize:
375 European ancestry trios, 1,395 European ancestry cases, 1,603 European ancestry controls, 454 French Canadian founder trios, 466 French Canadian founder cases, 358 French Canadian founder controls


dbdate: 11/25/2008
author: Maeda S
date: 08/01/2007
journal: Kidney Int Suppl
trait: Type 2 diabetes nephropathy
initial_samplesize: 94 Japanese ancestry cases, 94 Japanese ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17653210?ordinalpos=6&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
Genetic variations associated with diabetic nephropathy and type II diabetes in a Japanese population.


dbdate: 11/25/2008
author: Shifman S
date: 07/31/2007
journal: Mol Psychiatry
study: A whole genome association study of neuroticism using DNA pooling.
trait: Neuroticism
initial_samplesize: 1,038 European ancestry cases, 1,016 European ancestry controls
replication_samplesize: 831 European ancestry cases, 702 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17667963?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Hafler DA
date: 07/29/2007
journal: N Engl J Med
study: Risk alleles for multiple sclerosis identified by a genomewide study.
trait: Multiple sclerosis
initial_samplesize: 931 European ancestry trios, 2,431 European ancestry controls
replication_samplesize: 609 European ancestry trios, 2,322 European ancestry cases, 2,987 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17660530?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Scuteri A
date: 07/20/2007
journal: PLoS Genet
trait: Obesity-related traits
initial_samplesize: 4,741 Sardinia individuals
replication_samplesize: 3,205 African American, Hispanic, and European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/17658951?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits.


dbdate: 11/25/2008
author: Stefansson H
date: 07/19/2007
journal: N Engl J Med
study: A genetic risk factor for periodic limb movements in sleep.
trait: Restless legs syndrome
initial_samplesize: 306 European ancestry cases, 15,664 European ancestry controls
replication_samplesize: 311 European ancestry cases, 1,895 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17634447?ordinalpos=4&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Samani NJ
date: 07/18/2007
journal: N Engl J Med
study: Genomewide association analysis of coronary artery disease.
trait: Coronary heart disease
initial_samplesize: 1,926 European ancestry cases, 2,938 European ancestry controls
replication_samplesize: 875 European ancestry cases, 1,644 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17634449?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Winkelmann J
date: 07/18/2007
journal: Nat Genet
trait: Restless legs syndrome
initial_samplesize: 401 European ancestry cases, 1,644 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17637780?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
Genome-wide association study of restless legs syndrome identifies common variants in three genomic regions.

replication_samplesize:
906 European ancestry cases, 891 European ancestry controls, 255 French Canadian cases, 287 French Canadian controls


dbdate: 11/25/2008
author: Buch S
date: 07/15/2007
journal: Nat Genet
trait: Gallstones
initial_samplesize: 280 European ancestry cases, 360 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17632509?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
A genome-wide association scan identifies the hepatic cholesterol transporter ABCG8 as a susceptibility factor for human gallstone disease.

replication_samplesize:
1,833 European ancestry cases, 1,035 European ancestry controls, 167 Hispanic cases, 167 Hispanic controls


dbdate: 11/25/2008
author: Hakonarson H
date: 07/15/2007
journal: Nature
study: A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene.
trait: Type 1 diabetes
initial_samplesize: 467 European ancestry trios, 561 European ancestry cases, 1,143 European ancestry controls
replication_samplesize: 390 European ancestry trios, 1,333 European ancestry cases from 549 families
link:
http://www.ncbi.nlm.nih.gov/pubmed/17632545?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Tomlinson I
date: 07/08/2007
journal: Nat Genet
trait: Colorectal cancer
initial_samplesize: 930 European ancestry cases, 960 European ancestry controls
replication_samplesize: 7,334 European ancestry cases, 5,246 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17618284?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21.


dbdate: 11/25/2008
author: Zanke BW
date: 07/08/2007
journal: Nat Genet
trait: Colorectal cancer
initial_samplesize: 1,257 Other ancestry cases, 1,336 Other ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17618283?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24.

replication_samplesize:
5,084 European ancestry cases, 5,388 European ancestry controls, 1,139 Other ancestry cases, 1,055 European ancestry controls


dbdate: 11/25/2008
author: Gudbjartsson DF
date: 07/01/2007
journal: Nature
study: Variants conferring risk of atrial fibrillation on chromosome 4q25.
trait: Atrial fibrillation/atrial flutter
initial_samplesize: 550 European ancestry cases, 4,476 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17603472?ordinalpos=5&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

replication_samplesize:
3,030 European ancestry cases, 14,780 European ancestry controls, 333 Han Chinese ancestry cases, 2,836 Han Chinese ancestry controls


dbdate: 11/25/2008
author: Gudmundsson J
date: 07/01/2007
journal: Nat Genet
trait: Prostate cancer
initial_samplesize: 1,501 European ancestry cases, 11,290 European ancestry controls
replication_samplesize: 1,992 European ancestry cases, 3,058 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17603485?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes.


dbdate: 11/25/2008
author: Salonen JT
date: 06/26/2007
journal: Am J Hum Genet
study: Type 2 diabetes whole-genome association study in four populations: the DiaGen consortium.
trait: Type 2 diabetes
replication_samplesize: 2,573 European ancestry cases, 2,776 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17668382?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

initial_samplesize:
201 Finland founder cases, 200 Finland founder controls, 200 Ashkenazi Jewish cases, 197 Ashkenazi Jewish controls, 99 European ancestry cases, 100 European ancestry controls


dbdate: 11/25/2008
author: van Heel DA
date: 06/10/2007
journal: Nat Genet
trait: Celiac disease
initial_samplesize: 778 European ancestry cases, 1,422 European ancestry controls
replication_samplesize: 991 European ancestry cases, 1,489 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17558408?ordinalpos=4&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21.


dbdate: 11/25/2008
author: Reiman EM
date: 06/07/2007
journal: Neuron
study: GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers.
trait: Alzheimer's disease (late onset)
initial_samplesize: 446 cases, 290 controls
replication_samplesize: 415 Other ancestry cases, 260 Other ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17553421?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Parkes M
date: 06/06/2007
journal: Nat Genet
trait: Crohn's disease
initial_samplesize: 1,748 cases, 2,938 controls
replication_samplesize: 1,182 European ancestry cases, 2,024 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17554261?ordinalpos=4&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility.


dbdate: 11/25/2008
author: Todd JA
date: 06/06/2007
journal: Nat Genet
study: Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes.
trait: Type 1 diabetes
initial_samplesize: 2,000 European ancestry cases, 3,000 European ancestry controls
replication_samplesize: 2,997 European ancestry trios, 4,000 European ancestry cases, 5,000 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17554260?ordinalpos=11&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Hunter DJ
date: 05/27/2007
journal: Nat Genet
trait: Breast cancer
initial_samplesize: 1,145 European ancestry cases, 1,142 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17529973?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer.

replication_samplesize:
874 European ancestry cases, 1,478 European ancestry controls, 302 Other ancestry cases, 594 Other ancestry controls


dbdate: 11/25/2008
author: Stacey SN
date: 05/27/2007
journal: Nat Genet
trait: Breast cancer
initial_samplesize: 1,599 European ancestry cases, 11,546 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17529974?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
Common variants on chromosomes 2q35 and 16q12 confer susceptibility to estrogen receptor-positive breast cancer.

replication_samplesize:
2,954 European ancestry cases, 5,967 European ancestry controls, Up to 561 Japanese ancestry cases, Up to 565 Japanese ancestry control, Up to 422 Afican American cases, Up to 448 African American controls, Up to 418 Hispanic cases, Up to 422 Hispanic controls, Up to 148 Other ancestry cases, Up to 293 Other ancestry controls


dbdate: 11/25/2008
author: Baum AE
date: 05/08/2007
journal: Mol Psychiatry
trait: Bipolar disorder
initial_samplesize: 461 European ancestry cases, 563 European ancestry controls
replication_samplesize: 772 European ancestry cases, 876 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17486107?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder.


dbdate: 11/25/2008
author: Matarin M
date: 05/06/2007
journal: Lancet Neurol
trait: Stroke
initial_samplesize: 259 European ancestry cases, 269 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17434096?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
A genome-wide genotyping study in patients with ischaemic stroke: initial analysis and data release.


dbdate: 11/25/2008
author: Helgadottir A
date: 05/03/2007
journal: Science
study: A common variant on chromosome 9p21 affects the risk of myocardial infarction.
trait: Myocardial infarction
initial_samplesize: 1,607 European ancestry cases, 6,728 European ancestry controls
replication_samplesize: 2,980 European ancestry cases, 6,309 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17478679?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 02/13/2009
author: Saxena R
date: 04/26/2007
journal: Science
study: Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.
trait: Triglycerides
initial_samplesize: Up to 5,217 European ancestry individuals
link:
http://www.ncbi.nlm.nih.gov/pubmed/17463246?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Scott LJ
date: 04/26/2007
journal: Science
trait: Type 2 diabetes
initial_samplesize: 1,161 European ancestry cases, 1,174 European ancestry controls
replication_samplesize: 1,215 European ancestry cases, 1,258 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17463248?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants.


dbdate: 11/25/2008
author: Steinthorsdottir V
date: 04/26/2007
journal: Nat Genet
study: A variant in CDKAL1 influences insulin response and risk of type 2 diabetes.
trait: Type 2 diabetes
initial_samplesize: 1,399 European ancestry cases, 5,275 European ancestry controls
replication_samplesize: 2,174 European ancestry cases, 7,287 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17460697?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Zeggini E
date: 04/26/2007
journal: Science
study: Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes.
trait: Type 2 diabetes
initial_samplesize: 1,924 European ancestry cases, 2,938 European ancestry controls
replication_samplesize: 3,757 European ancestry cases, 5,346 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17463249?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Rioux JD
date: 04/15/2007
journal: Nat Genet
trait: Crohn's disease
initial_samplesize: 946 Other ancestry cases, 977 Other ancestry controls
replication_samplesize: 530 Other ancestry trios, 353 Other ancestry cases, 207 Other ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17435756?ordinalpos=4&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis.


dbdate: 11/25/2008
author: Frayling TM
date: 04/12/2007
journal: Science
trait: Body mass index
initial_samplesize: 5,483 European ancestry type 2 diabetes cases, 5,174 European ancestry controls
replication_samplesize: 19,424 European ancestry adults, 10,172 European ancestry children
link:
http://www.ncbi.nlm.nih.gov/pubmed/17434869?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity.


dbdate: 11/25/2008
author: Coon KD
date: 04/01/2007
journal: J Clin Psychiatry
trait: Alzheimer's disease (late onset)
initial_samplesize: 664 European ancestry cases, 422 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17474819?ordinalpos=4&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease.


dbdate: 11/25/2008
author: Gudmundsson J
date: 04/01/2007
journal: Nat Genet
study: Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24.
trait: Prostate cancer
initial_samplesize: 1,453 European ancestry cases, 3,064 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17401366?ordinalpos=26&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

replication_samplesize:
1,210 European ancestry cases, 2,445 European ancestry controls; 373 African American cases, 372 African American controls


dbdate: 11/25/2008
author: Hanson RL
date: 04/01/2007
journal: Diabetes
trait: End-stage renal disease
initial_samplesize: 105 Pima Indian cases, 102 Pima indian controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17395743?ordinalpos=8&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
Identification of PVT1 as a candidate gene for end-stage renal disease in type 2 diabetes using a pooling-based genome-wide single nucleotide polymorphism association study.


dbdate: 11/25/2008
author: Yeager M
date: 04/01/2007
journal: Nat Genet
study: Genome-wide association study of prostate cancer identifies a second risk locus at 8q24.
trait: Prostate cancer
initial_samplesize: 1,172 European ancestry cases, 1,157 European ancestry controls
replication_samplesize: 3,124 European ancestry cases, 3,142 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17401363?ordinalpos=5&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Lencz T
date: 03/20/2007
journal: Mol Psychiatry
study: Converging evidence for a pseudoautosomal cytokine receptor gene locus in schizophrenia.
trait: Schizophrenia
initial_samplesize: 178 European ancestry cases, 144 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17522711?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Libioulle C
date: 03/05/2007
journal: PLoS Genet
link: http://www.ncbi.nlm.nih.gov/pubmed/17447842
trait: Crohn's disease
initial_samplesize: 547 European ancestry cases, 928 European ancestry controls
replication_samplesize: 1,266 European ancestry cases, 559 European ancestry controls, Up to 428 European ancestry trios
study:
Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4.


dbdate: 11/25/2008
author: Schymick JC
date: 02/20/2007
journal: Lancet Neurol
trait: Amyotrophic lateral sclerosis
initial_samplesize: 276 European ancestry cases, 271 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17362836?ordinalpos=5&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
Genome-wide genotyping in amyotrophic lateral sclerosis and neurologically normal controls: first stage analysis and public release of data.


dbdate: 11/25/2008
author: Sladek R
date: 02/11/2007
journal: Nature
study: A genome-wide association study identifies novel risk loci for type 2 diabetes.
trait: Type 2 diabetes
initial_samplesize: 661 European ancestry cases, 614 European ancestry controls
replication_samplesize: 2,617 European ancestry cases, 2,894 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17293876?ordinalpos=24&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Bierut LJ
date: 12/07/2006
journal: Hum Mol Genet
study: Novel genes identified in a high-density genome wide association study for nicotine dependence.
trait: Nicotine dependence
initial_samplesize: 482 European ancestry cases, 466 European ancestry controls
replication_samplesize: 568 European ancestry cases, 413 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17158188?ordinalpos=4&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Duerr RH
date: 10/26/2006
journal: Science
study: A genome-wide association study identifies IL23R as an inflammatory bowel disease gene.
trait: Inflammatory bowel disease
initial_samplesize: 547 European ancestry cases, 548 European ancestry controls
replication_samplesize: 1,151 Other ancestry cases from 595 families, 433 Other ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17068223?ordinalpos=8&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Dewan A
date: 10/19/2006
journal: Science
study: HTRA1 promoter polymorphism in wet age-related macular degeneration.
trait: Age-related macular degeneration (wet)
initial_samplesize: 96 Southeast Asian ancestry cases, 130 Southeast Asian ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17053108?ordinalpos=5&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


dbdate: 11/25/2008
author: Fung HC
date: 09/28/2006
journal: Lancet Neurol
trait: Parkinson's disease
initial_samplesize: 267 European ancestry cases, 270 European ancestry controls
link:
http://www.ncbi.nlm.nih.gov/pubmed/17052657?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

study:
Genome-wide genotyping in Parkinson's disease and neurologically normal controls: first stage analysis and public release of data.


dbdate: 11/25/2008
author: Arking DE
date: 04/30/2006
journal: Nat Genet
study: A common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarization.
trait: QT interval
initial_samplesize: 100 European ancestry females > 445ms, 100 European ancestry females < 386ms
link:
http://www.ncbi.nlm.nih.gov/pubmed/16648850?ordinalpos=10&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

replication_samplesize:
200 European ancestry females > 85th pct, 200 European ancestry females < 15th pct, 4,451 European ancestry individuals


dbdate: 11/25/2008
author: Maraganore DM
date: 09/09/2005
journal: Am J Hum Genet
study: High-resolution whole-genome association study of Parkinson disease.
trait: Parkinson's disease
link:
http://www.ncbi.nlm.nih.gov/pubmed/16252231?ordinalpos=6&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

initial_samplesize:
381 European ancestry cases, 363 European ancestry controls, 62 Other ancestry cases,79 Other ancestry controls, 1 Asian ancestry control from 443 sibships

replication_samplesize:
269 European ancestry cases, 272 European ancestry controls, 62 Other ancestry cases, 60 Other ancesty controls, 1 Asian ancestry case


# assocs

region: 12q13.2
chrom: 12
mapped_gene: OR6C64P
strongest_risk_snp: rs12230513
or_beta: 2.69
reported_genes:
OR9K2, OR10A7, OR6C74, OR6C6, OR6C1, OR6C3, OR6C75, OR6C65, OR6C76, OR6C2, OR6C70, OR6C68, OR6C4, OR10P1


region: 10q24.32
chrom: 10
mapped_gene: AS3MT;C10orf32-ASMT
strongest_risk_snp: rs7085104
strongest_risk_allele: A
or_beta: 1.11
reported_genes:
C10orf32, AS3MT, CALHM1, CALHM2, CALHM3,CNNM2, CYP17A1, INA, MIR1307, NT5C2, PCGF6, PDCD11, SFXN2, ST13P13, TAF5, USMG5, WBP1L


region: 19p13.11
chrom: 19
mapped_gene: MAU2 - GATAD2A
strongest_risk_snp: rs2905424
strongest_risk_allele: T
or_beta: 1.09
reported_genes:
MAU2, CILP2, GATAD2A, GMIP, HAPLN4, LPAR2, MIR640, NCAN, NDUFA13, PBX4, SUGP1, TM6SF2, TSSK6, YJEFN3


region: 3p21.1
chrom: 3
mapped_gene: ITIH3
strongest_risk_snp: rs4687552
strongest_risk_allele: T
or_beta: 1.09
reported_genes:
ITIH3, ALAS1, ALDOAP1, BAP1, C3orf78, DNAH1, GLT8D1, GLYCTK, GNL3, ITIH1, ITIH4, MIR135A1, MIRLET7G, MUSTN1, NEK4, NISCH, NT5DC2, PBRM1, PHF7, PPM1M, RFT1, SEMA3G, SFMBT1, SPCS1, STAB1, TLR9, TMEM110, TNNC1, TWF2, WDR82


region: 1q21.3
chrom: 1
mapped_gene: KCNN3
strongest_risk_snp: rs1218582
strongest_risk_allele: G
or_beta: 1.06
reported_genes:
ADAM15, ADAR, CKS1B, DCST1, DCST2, DPM3, EFNA1, EFNA3,EFNA4, FLAD1, KCNN3, LENEP, LOC10050, LOC100505666,MIR4258, PBXIP1, PMVK, PYGO2, SHC1, SLC50A1, ZBTB7B


region: 6p21.32
chrom: 6
mapped_gene: NOTCH4
strongest_risk_snp: rs3096702
strongest_risk_allele: A
or_beta: 1.07
reported_genes:
AGER, AGPAT1, ATF6B, BTNL2, C2, C4A, C4B, C6orf10, CFB,CYP21A1P, CYP21A2, DOM3Z, EGFL8, FKBPL, GPSM3,HCG23, HLA-DQA1, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB5,HLA-DRB6, LOC10029, LOC100293534, LOC10050,LOC100507547, MIR1236, NOTCH4, PBX2, PPT2, PPT2-EGF,PPT2-EGFL8, PRRT1, RDBP, RNF5, RNF5P1, SKIV2L, STK19,TNXA, TNXB


region: 10q24.32
chrom: 10
mapped_gene: TRIM8
strongest_risk_snp: rs3850699
strongest_risk_allele: A
or_beta: 1.10
reported_genes:
ACTR1A, ARL3, AS3MT, C10orf32, C10orf32-AS3MT, C10orf95,CNNM2, CUEDC2, CYP17A1, FBXL15, LOC100505761,MIR146B, PSD, SFXN2, SUFU, TMEM180, TRIM8, WBP1L


region: 20q13.33
chrom: 20
mapped_gene: RBBP8NL - GATA5
strongest_risk_snp: rs2427345
strongest_risk_allele: G
or_beta: 1.06
reported_genes:
ADRM1, C20orf15, C20orf151, C20orf166, C20orf166-AS1,CABLES2, GATA5, GTPBP5, HRH3, LAMA5, MIR1-1,MIR133A2, MIR4758, OSBPL2, RPS21


region: 20q13.33
chrom: 20
mapped_gene: ZGPAT
strongest_risk_snp: rs6062509
strongest_risk_allele: A
or_beta: 1.12
reported_genes:
ABHD16B, ARFRP1, C20orf195, DNAJC5, EEF1A2, GMEB2,LIME1, LOC100505815, MIR1914, MIR647, MIR941-1,MIR941-2, MIR941-3, MIR941-4, PPDPF, PRIC285, PRPF6,PTK6, RTEL1, RTEL1-TN, RTEL1-TNFRSF6B, SAMD10,SLC2A4RG, SRMS, STMN3, TNFRSF6B, TPD52L2, UCKL1,UCKL1-AS1, ZBTB46, ZGPAT, ZNF512B


region: 17q12
chrom: 17
mapped_gene: HNF1B
strongest_risk_snp: rs757210
strongest_risk_allele: G
or_beta: 1.12
reported_genes:
HNF1B, ACACA, C17orf78, TADA2A, DUSP14, SYNRG, DDX52, TBC1D3F, TBC1D3, MRPL45, GPR179, SOCS7, ARHGAP23


region: 5q31.3
chrom: 5
reported_genes: PCDHAC1
strongest_risk_snp: rs31872
strongest_risk_allele: G
mapped_gene:
PCDHA9;PCDHAC2;PCDHAC1;PCDHA13;PCDHA12;PCDHA11;PCDHA10;PCDHA8;PCDHA7;PCDHA6;PCDHA5;PCDHA4;PCDHA3;PCDHA2;PCDHA1


region: 11q13.2
chrom: 11
mapped_gene: C11orf80
strongest_risk_snp: rs10896135
strongest_risk_allele: G
or_beta: 1.12
reported_genes:
ZDHHC24, YIF1A, TMEM151A, SYT12, SPTBN2,SLC29A2, SF3B2, RIN1, RCE1, RBM4B, RBM4, RBM14, RAB1B, PELI3, PC, PACS1, NPAS4, MRPL11, LRFN4, KLC2, GAL3ST3, DPP3, CTSF, CNIH2, CD248, CCS, CCDC87, C11orf86, C11orf80, BRMS1, BBS1, B3GNT1, ACTN3


region: 3p21.1
chrom: 3
mapped_gene: ITIH3
strongest_risk_snp: rs736408
strongest_risk_allele: C
or_beta: 1.10
reported_genes:
WDR82, TWF2, TNNC1, TMEM110, TLR9, STAB1,SPCS1, SNORD69, SNORD19, SNORD19B, SFMBT1, SEMA3G, RFT1, PRKCD, PPM1M, PHF7, PBRM1, NT5DC2, NISCH, NEK4, MUSTN1, LOC440957, ITIH1, ITIH3, ITIH4, GNL3, GLYCTK, GLT8D1, DNAH1, BAP1, ALAS1


region: 6p21.33
chrom: 6
mapped_gene: DDX39B;SNORD117;ATP6V1G2-DDX39B
strongest_risk_snp: rs2734583
or_beta: 66.80
reported_genes:
BAT1, HCP5, MICC, PPIAP9, PSORS1C1, POLR2LP, CCHCR1, TCF19, POU5F1, HLA-C, HCP5, PSORS1C3, HLA-B*5801


