#TARGET FUNCTIONS ##GABABR What: Gamma-aminobutyric acid receptor Function: Receptors receive signals that could be related to signals needed for immediate actions such as closing the shell or moving in response to stimuli ##PGE/EP4 What: Prostaglandin E receptor 4 (EP4) Function: Receptor for Prostaglandin E2 which suppresses inflammation due to injury ##HSPb11 What: Heat Shock Protein beta-11 Function: Small Heat Shock Protein also used during gonad development ##BMP2 What: Bone Morphogenic Protein 2 Function: Directs calcification in shell creation ##PGRP What: Peptidoglycan recognition protein Function: Recognition of bacteria in an immune response Works with: TNFa, HSP70 ##HSP70 What: Heat Shock Protein 70kDa Function: Molecular chaperone and protein preservation in heat response Works with: PGRP ##H2A What: Histone 2A Function: One of 5 main Histone Proteins involved in the structure of chromatin and the open reading frame of DNA Works with: H3.3, H2A.V ##H2A.V What: Histone 2A.V Function: One of 5 main Histone Proteins involved in the structure of chromatin and the open reading frame of DNA Works with: H2A, H3.3 ##H3.3 What: Histone 3.3 Function: One of 5 main Histone Proteins involved in the structure of chromatin and the open reading frame of DNA Works with: H2A, H2A.V ##TLR What: Toll-like Receptor 2 Function: Recognize foreign pathogens and endogenous materials for consumption by phagocytes in early stages of inflammation. Works with: TNFa ##Actin What: Actin Function: Globular protein that forms microfilaments ##CRAF What: Tumor Necrosis Factor receptor-associated factor 3 Function: Related to immune response specifically cell death initiation Works with: NFkBINA ##CARM What: Coactivator-associated arginine methyltransferase 1 Function: Transfers methyl groups to H3 and H4 to change how DNA is bound up in Chromatin Works with: H3.3, H2A.V, H2A ##GRB2 What: Growth factor receptor-bound protein 2 Function: Signal Transduction/Cell Communication ##p29ING What: Inhibitor of growth protein 4 Function: Inhibits cell growth and induces apoptosis