Coefficient of Variation	GO IDs																																																																																																																					
CHOYP_ABCA1.2.3	P41233	m.11687	sp	ABCA1_MOUSE	40	675	344	13	258	903	1180	1822	1.21E-130	437	ABCA1_MOUSE	reviewed	ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ABC-1) (ATP-binding cassette 1)	x	Abca1 Abc1	Mus musculus (Mouse)	2261	"cellular response to cholesterol [GO:0071397]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to retinoic acid [GO:0071300]; cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; endosomal transport [GO:0016197]; G-protein coupled receptor signaling pathway [GO:0007186]; high-density lipoprotein particle assembly [GO:0034380]; interleukin-1 beta secretion [GO:0050702]; intracellular cholesterol transport [GO:0032367]; lipoprotein biosynthetic process [GO:0042158]; lipoprotein metabolic process [GO:0042157]; lysosome organization [GO:0007040]; peptide secretion [GO:0002790]; phagocytosis, engulfment [GO:0006911]; phospholipid efflux [GO:0033700]; phospholipid homeostasis [GO:0055091]; phospholipid translocation [GO:0045332]; platelet dense granule organization [GO:0060155]; positive regulation of cAMP biosynthetic process [GO:0030819]; positive regulation of cholesterol efflux [GO:0010875]; protein lipidation [GO:0006497]; regulation of Cdc42 protein signal transduction [GO:0032489]; response to drug [GO:0042493]; response to laminar fluid shear stress [GO:0034616]; response to low-density lipoprotein particle [GO:0055098]; response to nutrient [GO:0007584]; reverse cholesterol transport [GO:0043691]"		0	0	0	PF00005;	59	m.11687	135848.2857	5214020.5	320156	1375048.889	232384.7143	267251.5556	520005.75	1782210.364	1596007.75	748949.4167	0.675294117	1.253314851	GO:0002790	GO:0005102	GO:0005524	GO:0005548	GO:0005794	GO:0005886	GO:0005887	GO:0006497	GO:0006911	GO:0007040	GO:0007186	GO:0007584	GO:0008203	GO:0008509	GO:0009897	GO:0010875	GO:0016197	GO:0017127	GO:0019905	GO:0030139	GO:0030819	GO:0031267	GO:0032367	GO:0032489	GO:0033344	GO:0033700	GO:0034185	GO:0034186	GO:0034188	GO:0034364	GO:0034380	GO:0034616	GO:0042157	GO:0042158	GO:0042493	GO:0042626	GO:0042632	GO:0043231	GO:0043691	GO:0045121	GO:0045332	GO:0045335	GO:0048471	GO:0050702	GO:0051117	GO:0055091	GO:0055098	GO:0060155	GO:0071222	GO:0071300	GO:0071397																																																																			
CHOYP_AIFM1.1.1	O95831	m.1582	sp	AIFM1_HUMAN	47.135	541	262	8	70	601	83	608	1.24E-157	468	AIFM1_HUMAN	reviewed	"Apoptosis-inducing factor 1, mitochondrial (EC 1.1.1.-) (Programmed cell death protein 8)"	x	AIFM1 AIF PDCD8	Homo sapiens (Human)	613	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cell redox homeostasis [GO:0045454]; cellular response to aldosterone [GO:1904045]; cellular response to estradiol stimulus [GO:0071392]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to nitric oxide [GO:0071732]; cellular response to oxygen-glucose deprivation [GO:0090650]; chromosome condensation [GO:0030261]; DNA catabolic process [GO:0006308]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; mitochondrial respiratory chain complex I assembly [GO:0032981]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; positive regulation of apoptotic process [GO:0043065]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of apoptotic DNA fragmentation [GO:1902510]; response to ischemia [GO:0002931]; response to L-glutamate [GO:1902065]; response to toxic substance [GO:0009636]		0	0	0	PF14721;PF07992;	222	m.1582	973976.6	84310	1359083.667	479589.75	315224.8	3251126.5	300368	479530.6	1802073.6	1379353.222	2.245341515	0.921483289	GO:0002931	GO:0003677	GO:0005634	GO:0005739	GO:0005743	GO:0005758	GO:0005829	GO:0006308	GO:0006915	GO:0006919	GO:0009055	GO:0009636	GO:0016174	GO:0016651	GO:0030182	GO:0030261	GO:0032981	GO:0043065	GO:0043525	GO:0045454	GO:0048471	GO:0051402	GO:0070059	GO:0070301	GO:0071392	GO:0071732	GO:0071949	GO:0090650	GO:1902065	GO:1902510	GO:1904045																																																																																							
CHOYP_BRAFLDRAFT_119799.1.1	P30044	m.23765	sp	PRDX5_HUMAN	59.524	168	66	1	18	183	43	210	7.18E-69	211	PRDX5_HUMAN	reviewed	"Peroxiredoxin-5, mitochondrial (EC 1.11.1.15) (Alu corepressor 1) (Antioxidant enzyme B166) (AOEB166) (Liver tissue 2D-page spot 71B) (PLP) (Peroxiredoxin V) (Prx-V) (Peroxisomal antioxidant enzyme) (TPx type VI) (Thioredoxin peroxidase PMP20) (Thioredoxin reductase)"	x	PRDX5 ACR1 SBBI10	Homo sapiens (Human)	214	cell redox homeostasis [GO:0045454]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; inflammatory response [GO:0006954]; NADPH oxidation [GO:0070995]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of transcription from RNA polymerase III promoter [GO:0016480]; positive regulation of collagen biosynthetic process [GO:0032967]; reactive nitrogen species metabolic process [GO:2001057]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; response to oxidative stress [GO:0006979]; response to reactive oxygen species [GO:0000302]		0	0	0	PF08534;	478	m.23765	23982944.17	13890076.81	4635772	2601289.75	17147594.83	1161584.636	5768779.182	967580.7	5408679.8	31874359.25	0.725709428	0.989366319	GO:0000302	GO:0001016	GO:0004601	GO:0005102	GO:0005615	GO:0005634	GO:0005737	GO:0005739	GO:0005759	GO:0005777	GO:0005782	GO:0005829	GO:0006954	GO:0006979	GO:0008379	GO:0016209	GO:0016480	GO:0031410	GO:0032967	GO:0034614	GO:0042744	GO:0043027	GO:0043066	GO:0043231	GO:0045454	GO:0046983	GO:0048471	GO:0051354	GO:0051920	GO:0060785	GO:0070062	GO:0070995	GO:0072541	GO:2001057																																																																																				
CHOYP_BRAFLDRAFT_90929.1.1	Q14831	m.54455	sp	GRM7_HUMAN	27.789	475	300	13	538	988	46	501	2.19E-46	184	GRM7_HUMAN	reviewed	Metabotropic glutamate receptor 7 (mGluR7)	x	GRM7 GPRC1G MGLUR7	Homo sapiens (Human)	915	"adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway [GO:0007196]; adult behavior [GO:0030534]; chemical synaptic transmission [GO:0007268]; conditioned taste aversion [GO:0001661]; multicellular organismal response to stress [GO:0033555]; negative regulation of adenylate cyclase activity [GO:0007194]; negative regulation of cAMP biosynthetic process [GO:0030818]; negative regulation of glutamate secretion [GO:0014050]; regulation of synaptic transmission, glutamatergic [GO:0051966]; sensory perception of smell [GO:0007608]; sensory perception of sound [GO:0007605]; short-term memory [GO:0007614]; transmission of nerve impulse [GO:0019226]"		0	0	0	PF00003;PF01094;PF07562;	1032	m.54454	93479	30483	43294	74151	132143	217504	35097	1817412.333	20942003.5	1019406.5	64.33254807	2.674513807	GO:0001642	GO:0001661	GO:0005245	GO:0005246	GO:0005509	GO:0005886	GO:0005887	GO:0005938	GO:0007194	GO:0007196	GO:0007268	GO:0007605	GO:0007608	GO:0007614	GO:0008066	GO:0010855	GO:0014050	GO:0016021	GO:0016595	GO:0019226	GO:0030165	GO:0030424	GO:0030425	GO:0030534	GO:0030818	GO:0032279	GO:0033555	GO:0042734	GO:0043198	GO:0043235	GO:0045211	GO:0048786	GO:0051966	GO:0070905																																																																																				
CHOYP_CATA.1.3	Q9PWF7	m.11120	sp	CATA_RUGRU	66.794	262	86	1	44	305	238	498	1.91E-124	369	CATA_RUGRU	reviewed	Catalase (EC 1.11.1.6)	x	cat	Rugosa rugosa (Japanese wrinkled frog) (Glandirana rugosa)	528	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]		0	0	0	PF00199;PF06628;	1164	m.11120	217389.2857	189117.2222	414395.2	616062.8462	733193.4286	391679.2727	255387.3	239523.8333	424081.4	375916.75	0.777173169	0.458616818	GO:0004096	GO:0005777	GO:0006979	GO:0020037	GO:0042744	GO:0046872																																																																																																																
CHOYP_CRYAB.2.5	P04792	m.23200	sp	HSPB1_HUMAN	37.234	94	57	2	46	138	89	181	2.28E-09	58.5	HSPB1_HUMAN	reviewed	Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27)	x	HSPB1 HSP27 HSP28	Homo sapiens (Human)	205	cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]		0	0	0	PF00011;	1764	m.23201	483273.625	372271.3333	7342004.5	286184.5	542089.5	246745.6667	4659260.889	1075265.714	1637214.4	3352081.083	1.215464473	1.196391219	GO:0000502	GO:0001895	GO:0005080	GO:0005615	GO:0005634	GO:0005737	GO:0005819	GO:0005829	GO:0005856	GO:0005886	GO:0005925	GO:0006446	GO:0006469	GO:0006928	GO:0006986	GO:0008426	GO:0009615	GO:0010506	GO:0019901	GO:0030018	GO:0031012	GO:0032731	GO:0035556	GO:0035924	GO:0038033	GO:0042535	GO:0042802	GO:0043066	GO:0043122	GO:0043130	GO:0043488	GO:0043536	GO:0044822	GO:0045766	GO:0048010	GO:0070062	GO:0070527	GO:1902176	GO:2001028																																																																															
CHOYP_DNJC3.1.1	Q27968	m.52309	sp	DNJC3_BOVIN	55.4	500	210	6	50	536	5	504	0	526	DNJC3_BOVIN	reviewed	"DnaJ homolog subfamily C member 3 (Interferon-induced, double-stranded RNA-activated protein kinase inhibitor) (Protein kinase inhibitor of 58 kDa) (Protein kinase inhibitor p58)"	x	DNAJC3 P58IPK	Bos taurus (Bovine)	504	cellular response to cold [GO:0070417]; negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation [GO:1903912]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of translation initiation in response to endoplasmic reticulum stress [GO:0036494]; response to unfolded protein [GO:0006986]		0	0	cd06257;	PF00226;PF09976;PF13181;	1897	m.52309	680976.5	340475.7143	285811.25	195196.1111	87705.2	422222.4286	100637.6	1724223.714	462403.7143	208907.375	1.835278254	1.069669022	GO:0004860	GO:0005783	GO:0005829	GO:0006469	GO:0006986	GO:0019901	GO:0036494	GO:0070417	GO:1903912																																																																																																													
CHOYP_DPER_GL22446.1.1	P04792	m.52315	sp	HSPB1_HUMAN	37.838	74	45	1	28	100	95	168	1.34E-11	61.2	HSPB1_HUMAN	reviewed	Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27)	x	HSPB1 HSP27 HSP28	Homo sapiens (Human)	205	cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]		0	0	0	PF00011;	1904	m.52315	636340	340809.8333	7943169.909	362777.6667	568209	237382.25	5959749.143	1408708.4	1734680.25	4352681.556	1.389988397	1.168746732	GO:0000502	GO:0001895	GO:0005080	GO:0005615	GO:0005634	GO:0005737	GO:0005819	GO:0005829	GO:0005856	GO:0005886	GO:0005925	GO:0006446	GO:0006469	GO:0006928	GO:0006986	GO:0008426	GO:0009615	GO:0010506	GO:0019901	GO:0030018	GO:0031012	GO:0032731	GO:0035556	GO:0035924	GO:0038033	GO:0042535	GO:0042802	GO:0043066	GO:0043122	GO:0043130	GO:0043488	GO:0043536	GO:0044822	GO:0045766	GO:0048010	GO:0070062	GO:0070527	GO:1902176	GO:2001028																																																																															
CHOYP_DPER_GL22446.1.1	P42930	m.52312	sp	HSPB1_RAT	35.443	79	50	1	46	123	93	171	3.49E-06	47.8	HSPB1_RAT	reviewed	Heat shock protein beta-1 (HspB1) (Heat shock 27 kDa protein) (HSP 27)	x	Hspb1 Hsp27	Rattus norvegicus (Rat)	206	aging [GO:0007568]; cellular response to butyrate [GO:1903545]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-11 [GO:0071348]; female pregnancy [GO:0007565]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced cell death [GO:1903202]; positive regulation of neuron projection development [GO:0010976]; response to angiotensin [GO:1990776]; response to ischemia [GO:0002931]; response to muscle stretch [GO:0035994]		0	0	0	PF00011;	1903	m.52311	150372	1061472	56760	1460974	15160	131588.5	1822599	21110	39365	431946	0.891381436	1.303305422	GO:0000502	GO:0002931	GO:0005634	GO:0005737	GO:0005819	GO:0005886	GO:0007565	GO:0007568	GO:0010976	GO:0030424	GO:0030425	GO:0031430	GO:0031674	GO:0035994	GO:0043066	GO:0043130	GO:0043204	GO:0045202	GO:0070301	GO:0071348	GO:0097512	GO:0098839	GO:1903202	GO:1903545	GO:1990776																																																																																													
CHOYP_G6PD.1.2	P05370	m.38380	sp	G6PD_RAT	68.487	476	140	5	62	530	9	481	0	692	G6PD_RAT	reviewed	Glucose-6-phosphate 1-dehydrogenase (G6PD) (EC 1.1.1.49)	x	G6pdx G6pd	Rattus norvegicus (Rat)	515	"cellular response to oxidative stress [GO:0034599]; cholesterol biosynthetic process [GO:0006695]; erythrocyte maturation [GO:0043249]; glucose 6-phosphate metabolic process [GO:0051156]; glucose metabolic process [GO:0006006]; glutathione metabolic process [GO:0006749]; NADPH regeneration [GO:0006740]; NADP metabolic process [GO:0006739]; negative regulation of cell growth involved in cardiac muscle cell development [GO:0061052]; negative regulation of protein glutathionylation [GO:0010734]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; pentose biosynthetic process [GO:0019322]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, oxidative branch [GO:0009051]; positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel [GO:1904879]; regulation of neuron apoptotic process [GO:0043523]; response to ethanol [GO:0045471]; response to food [GO:0032094]; response to iron(III) ion [GO:0010041]; response to organic cyclic compound [GO:0014070]; ribose phosphate biosynthetic process [GO:0046390]; substantia nigra development [GO:0021762]"		PATHWAY: Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.	0	0	PF02781;PF00479;	2201	m.38380	1144157	3013439.8	549546.5385	607411.3077	1562046.636	428645.9091	6152029.4	527677.4545	567266.2857	1130303.455	1.280563194	1.140978726	GO:0004345	GO:0005536	GO:0005634	GO:0005813	GO:0005829	GO:0006006	GO:0006098	GO:0006695	GO:0006739	GO:0006740	GO:0006749	GO:0009051	GO:0009898	GO:0010041	GO:0010734	GO:0014070	GO:0019322	GO:0021762	GO:0030246	GO:0032094	GO:0034599	GO:0043231	GO:0043249	GO:0043523	GO:0045471	GO:0046390	GO:0050661	GO:0051156	GO:0061052	GO:0070062	GO:1904879	GO:2000378																																																																																						
CHOYP_GSK3B.1.1	Q9WV60	m.62139	sp	GSK3B_MOUSE	79.167	408	78	4	1	401	1	408	0	666	GSK3B_MOUSE	reviewed	Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)	x	Gsk3b	Mus musculus (Mouse)	420	aging [GO:0007568]; axonogenesis [GO:0007409]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in positive regulation of apoptotic process [GO:0044337]; cell migration [GO:0016477]; cell proliferation [GO:0008283]; cellular response to dopamine [GO:1903351]; cellular response to erythropoietin [GO:0036018]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-3 [GO:0036016]; cellular response to iron(II) ion [GO:0071282]; cellular response to lithium ion [GO:0071285]; cellular response to mechanical stimulus [GO:0071260]; circadian rhythm [GO:0007623]; cytoskeleton organization [GO:0007010]; epithelial to mesenchymal transition [GO:0001837]; ER overload response [GO:0006983]; establishment of cell polarity [GO:0030010]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fat cell differentiation [GO:0045444]; glycogen metabolic process [GO:0005977]; hippocampus development [GO:0021766]; hypermethylation of CpG island [GO:0044027]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; myoblast fusion [GO:0007520]; myotube differentiation [GO:0014902]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of dendrite morphogenesis [GO:0050774]; negative regulation of dopaminergic neuron differentiation [GO:1904339]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron maturation [GO:0014043]; negative regulation of neuron migration [GO:2001223]; negative regulation of neuron projection development [GO:0010977]; negative regulation of NFAT protein import into nucleus [GO:0051534]; negative regulation of nitric-oxide synthase activity [GO:0051001]; negative regulation of protein binding [GO:0032091]; negative regulation of protein complex assembly [GO:0031333]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; organ morphogenesis [GO:0009887]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; phosphorylation [GO:0016310]; positive regulation of axon extension [GO:0045773]; positive regulation of cardiac muscle cell differentiation [GO:2000727]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of GTPase activity [GO:0043547]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901030]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein binding [GO:0032092]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of stem cell differentiation [GO:2000738]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein autophosphorylation [GO:0046777]; protein export from nucleus [GO:0006611]; protein localization to microtubule [GO:0035372]; protein phosphorylation [GO:0006468]; re-entry into mitotic cell cycle [GO:0000320]; regulation of gene expression by genetic imprinting [GO:0006349]; regulation of microtubule-based process [GO:0032886]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of neuron projection development [GO:0010975]; response to activity [GO:0014823]; response to angiotensin [GO:1990776]; response to drug [GO:0042493]; response to epinephrine [GO:0071871]; response to estradiol [GO:0032355]; response to insulin [GO:0032868]; response to insulin-like growth factor stimulus [GO:1990418]; response to L-glutamate [GO:1902065]; response to ultrasound [GO:1990478]; superior temporal gyrus development [GO:0071109]; Wnt signaling pathway [GO:0016055]		0	0	0	PF00069;	2283	m.62139	1432424.833	243861	732079	327384.2	105283.3333	515224	2014174	669985	1655806.667	180484	1.772480218	0.857598721	GO:0000320	GO:0001085	GO:0001837	GO:0001954	GO:0002039	GO:0004672	GO:0004674	GO:0005524	GO:0005634	GO:0005654	GO:0005737	GO:0005739	GO:0005813	GO:0005829	GO:0005886	GO:0005977	GO:0006349	GO:0006468	GO:0006611	GO:0006983	GO:0007010	GO:0007409	GO:0007520	GO:0007568	GO:0007623	GO:0008013	GO:0008283	GO:0009887	GO:0010614	GO:0010628	GO:0010800	GO:0010918	GO:0010975	GO:0010977	GO:0014043	GO:0014069	GO:0014823	GO:0014902	GO:0016020	GO:0016055	GO:0016301	GO:0016310	GO:0016477	GO:0018105	GO:0018107	GO:0019901	GO:0021766	GO:0030010	GO:0030424	GO:0030426	GO:0030529	GO:0030877	GO:0031333	GO:0031334	GO:0031625	GO:0032091	GO:0032092	GO:0032355	GO:0032436	GO:0032868	GO:0032886	GO:0033138	GO:0034236	GO:0034392	GO:0035372	GO:0035556	GO:0035729	GO:0036016	GO:0036018	GO:0042493	GO:0043025	GO:0043066	GO:0043197	GO:0043198	GO:0043227	GO:0043407	GO:0043525	GO:0043547	GO:0044027	GO:0044297	GO:0044337	GO:0045121	GO:0045444	GO:0045773	GO:0045944	GO:0046777	GO:0046827	GO:0048168	GO:0048471	GO:0048661	GO:0050321	GO:0050774	GO:0051001	GO:0051059	GO:0051534	GO:0060070	GO:0070059	GO:0070301	GO:0071109	GO:0071260	GO:0071282	GO:0071285	GO:0071871	GO:0097192	GO:1901030	GO:1901216	GO:1902065	GO:1903351	GO:1904339	GO:1990418	GO:1990478	GO:1990776	GO:1990909	GO:2000463	GO:2000573	GO:2000727	GO:2000738	GO:2001223
CHOYP_HMCN1.44.44	A4IGL7	m.67044	sp	PXDN_XENTR	27.966	354	217	15	7	355	287	607	2.55E-29	124	PXDN_XENTR	reviewed	Peroxidasin (EC 1.11.1.7)	x	pxdn pxn	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	1457	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]		0	0	0	PF03098;PF07679;PF13855;PF00093;	2324	m.67044	550553.4	25633	NA	616589.5	41867	860098	102608	122130.5	322093	1078181.333	1.610253998	0.929128752	GO:0004601	GO:0005576	GO:0006979	GO:0020037	GO:0042744	GO:0046872																																																																																																																
CHOYP_HS74L.1.1	O95757	m.24610	sp	HS74L_HUMAN	51.001	849	390	10	1	833	1	839	0	850	HS74L_HUMAN	reviewed	Heat shock 70 kDa protein 4L (Heat shock 70-related protein APG-1) (Osmotic stress protein 94)	x	HSPA4L APG1 OSP94	Homo sapiens (Human)	839	protein folding [GO:0006457]; response to unfolded protein [GO:0006986]		0	0	0	PF00012;	2362	m.24610	2872580.188	112740.7857	4411670.667	1201676.667	1124563.429	1094158.353	3284951.133	2351002.5	872038.6667	267942.5882	0.809411259	0.800052181	GO:0005524	GO:0005634	GO:0005737	GO:0005829	GO:0006457	GO:0006986																																																																																																																
CHOYP_HS90A.1.3	P04809	m.7724	sp	HSP83_DROPS	80.184	434	84	1	18	451	269	700	0	735	HSP83_DROPS	reviewed	Heat shock protein 83 (HSP 82)	x	Hsp83 Hsp82 GA11622	Drosophila pseudoobscura pseudoobscura (Fruit fly)	717	protein folding [GO:0006457]; response to stress [GO:0006950]		0	0	0	PF02518;PF00183;	2363	m.7724	7325354.96	10949054.77	9864588.92	5515392.909	5017594.406	7180385.591	13770965.14	6327870.893	59548259.7	3882865.063	2.34563455	1.286826464	GO:0005524	GO:0005737	GO:0006457	GO:0006950																																																																																																																		
CHOYP_HS90A.3.3	Q90474	m.28299	sp	H90A1_DANRE	77.655	631	135	5	21	647	97	725	0	983	H90A1_DANRE	reviewed	Heat shock protein HSP 90-alpha 1	x	hsp90a.1 hsp90 hsp90a hsp90aa1 zgc:86652	Danio rerio (Zebrafish) (Brachydanio rerio)	725	leukocyte migration [GO:0050900]; muscle organ development [GO:0007517]; myofibril assembly [GO:0030239]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; protein folding [GO:0006457]; response to metal ion [GO:0010038]; response to stress [GO:0006950]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; skeletal myofibril assembly [GO:0014866]; striated muscle myosin thick filament assembly [GO:0071688]		0	0	0	PF02518;PF00183;	2365	m.28299	6336167.448	9992789.118	8415240.6	5084407.194	4785630.914	5979604.593	12388561.62	5766617.969	53132814.89	3463185.139	2.332300095	1.28808981	GO:0005524	GO:0006457	GO:0006950	GO:0007517	GO:0010038	GO:0014866	GO:0030018	GO:0030235	GO:0030239	GO:0030240	GO:0030241	GO:0031672	GO:0042470	GO:0045429	GO:0048471	GO:0048769	GO:0050900	GO:0071688																																																																																																				
CHOYP_HYOU1.3.3	Q9Y4L1	m.28442	sp	HYOU1_HUMAN	43.75	208	108	3	2	207	739	939	5.24E-41	154	HYOU1_HUMAN	reviewed	Hypoxia up-regulated protein 1 (150 kDa oxygen-regulated protein) (ORP-150) (170 kDa glucose-regulated protein) (GRP-170)	x	HYOU1 GRP170 ORP150	Homo sapiens (Human)	999	cellular response to hypoxia [GO:0071456]; ER to Golgi vesicle-mediated transport [GO:0006888]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903382]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; receptor-mediated endocytosis [GO:0006898]; response to endoplasmic reticulum stress [GO:0034976]; response to ischemia [GO:0002931]		0	0	0	PF00012;	2406	m.28442	349834.6667	186919	5250015.75	857059	43037	349373.6667	765713.5	458386	121379.3333	39706.5	0.259397923	1.869121031	GO:0002931	GO:0005524	GO:0005576	GO:0005783	GO:0005788	GO:0005790	GO:0005925	GO:0006888	GO:0006898	GO:0016020	GO:0034663	GO:0034976	GO:0036498	GO:0051087	GO:0070062	GO:0071456	GO:0071682	GO:1903298	GO:1903382																																																																																																			
CHOYP_ISCW_ISCW008219.1.2	P08228	m.46822	sp	SODC_MOUSE	70.588	153	45	0	4	156	2	154	1.28E-74	223	SODC_MOUSE	reviewed	Superoxide dismutase [Cu-Zn] (EC 1.15.1.1)	x	Sod1	Mus musculus (Mouse)	154	activation of MAPK activity [GO:0000187]; aging [GO:0007568]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antibiotic [GO:0046677]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to nutrient levels [GO:0031667]; response to organic substance [GO:0010033]; response to oxidative stress [GO:0006979]; response to reactive oxygen species [GO:0000302]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]		0	0	cd00305;	PF00080;	2475	m.46822	3670563.4	468776.25	492295.75	89802.83333	365171.2222	320819.5	281210	369576.8571	1610264.2	335148	0.573470124	1.361991698	GO:0000187	GO:0000302	GO:0000303	GO:0001541	GO:0001819	GO:0001895	GO:0001975	GO:0002262	GO:0004784	GO:0005507	GO:0005615	GO:0005634	GO:0005654	GO:0005737	GO:0005739	GO:0005758	GO:0005764	GO:0005777	GO:0005829	GO:0005886	GO:0006749	GO:0006801	GO:0006879	GO:0006979	GO:0007283	GO:0007566	GO:0007568	GO:0007569	GO:0007605	GO:0007626	GO:0008089	GO:0008090	GO:0008217	GO:0008270	GO:0009408	GO:0010033	GO:0019226	GO:0019430	GO:0030346	GO:0031012	GO:0031045	GO:0031410	GO:0031667	GO:0032287	GO:0032839	GO:0032930	GO:0034465	GO:0035865	GO:0040014	GO:0042493	GO:0042542	GO:0042554	GO:0042802	GO:0043025	GO:0043066	GO:0043085	GO:0043087	GO:0043209	GO:0043234	GO:0043524	GO:0045471	GO:0045541	GO:0045859	GO:0046677	GO:0046688	GO:0046716	GO:0048365	GO:0048678	GO:0050665	GO:0051087	GO:0051881	GO:0060047	GO:0060052	GO:0060087	GO:0060088	GO:0070062	GO:0071276	GO:0071318	GO:0072593	GO:0097332	GO:1902177	GO:1904115																																				
CHOYP_ISCW_ISCW010532.2.4	Q9NL98	m.35454	sp	PRDX_ASCSU	73.846	195	51	0	1	195	1	195	8.32E-109	312	PRDX_ASCSU	reviewed	Peroxiredoxin (EC 1.11.1.15) (AsPrx) (Thioredoxin peroxidase)	x	0	Ascaris suum (Pig roundworm) (Ascaris lumbricoides)	195	cell redox homeostasis [GO:0045454]; response to oxidative stress [GO:0006979]		0	0	0	PF10417;PF00578;	2487	m.35454	512133.2857	399627.7778	254216.5714	592246.3333	459379.875	69883.16667	284040.1429	196095.6	1176951.833	368687	0.945009971	0.705391595	GO:0004601	GO:0005737	GO:0006979	GO:0008379	GO:0016209	GO:0045454																																																																																																																
CHOYP_ISCW_ISCW012366.1.1	P53563	m.3692	sp	B2CL1_RAT	30.921	152	96	3	115	258	82	232	7.30E-17	80.5	B2CL1_RAT	reviewed	Bcl-2-like protein 1 (Bcl2-L-1) (Apoptosis regulator Bcl-X)	x	Bcl2l1 Bclx Blc2l	Rattus norvegicus (Rat)	233	aging [GO:0007568]; apoptotic process [GO:0006915]; cerebral cortex development [GO:0021987]; cytokinesis [GO:0000910]; endocytosis [GO:0006897]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of apoptotic process [GO:0043066]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; ovarian follicle development [GO:0001541]; regulation of apoptotic process [GO:0042981]; response to electrical stimulus [GO:0051602]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to inorganic substance [GO:0010035]; response to ischemia [GO:0002931]; response to lead ion [GO:0010288]; response to organic cyclic compound [GO:0014070]; response to organonitrogen compound [GO:0010243]; response to oxidative stress [GO:0006979]; response to peptide hormone [GO:0043434]		0	0	0	PF00452;PF02180;	2495	m.3691	5954836.833	449406	266357.1667	375873	197061.8334	206763.75	2988434.8	1828123.5	183205.75	485289.75	0.785778999	1.452370643	GO:0000910	GO:0001541	GO:0001666	GO:0002931	GO:0005739	GO:0005740	GO:0005741	GO:0005743	GO:0005759	GO:0005813	GO:0005829	GO:0006897	GO:0006915	GO:0006979	GO:0007093	GO:0007568	GO:0008630	GO:0010035	GO:0010243	GO:0010288	GO:0014070	GO:0016021	GO:0021987	GO:0030054	GO:0030672	GO:0031965	GO:0042542	GO:0042803	GO:0042981	GO:0043027	GO:0043066	GO:0043434	GO:0046982	GO:0051400	GO:0051602	GO:0097192	GO:0097371	GO:2001243																																																																																
CHOYP_ISCW_ISCW014481.1.1	P56524	m.61217	sp	HDAC4_HUMAN	44.028	1013	420	27	99	1005	93	1064	0	732	HDAC4_HUMAN	reviewed	Histone deacetylase 4 (HD4) (EC 3.5.1.98)	x	HDAC4 KIAA0288	Homo sapiens (Human)	1084	"B cell activation [GO:0042113]; B cell differentiation [GO:0030183]; cardiac muscle hypertrophy in response to stress [GO:0014898]; cellular response to mechanical stimulus [GO:0071260]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to tumor necrosis factor [GO:0071356]; chromatin modification [GO:0016568]; chromatin remodeling [GO:0006338]; histone deacetylation [GO:0016575]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; inflammatory response [GO:0006954]; negative regulation of cell proliferation [GO:0008285]; negative regulation of glycolytic process [GO:0045820]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nervous system development [GO:0007399]; osteoblast development [GO:0002076]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of cell proliferation [GO:0008284]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein sumoylation [GO:0033235]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of gene expression, epigenetic [GO:0040029]; regulation of protein binding [GO:0043393]; regulation of skeletal muscle fiber development [GO:0048742]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; response to drug [GO:0042493]; response to interleukin-1 [GO:0070555]; skeletal system development [GO:0001501]; transcription, DNA-templated [GO:0006351]"		0	0	0	PF12203;PF00850;	2505	m.61217	1761534	1532941	3260356.75	682510	30869	NA	20216773.75	903436	3183750	95814	4.196317118	1.810861403	GO:0000118	GO:0000122	GO:0001025	GO:0001047	GO:0001501	GO:0002076	GO:0003682	GO:0003714	GO:0004407	GO:0005634	GO:0005654	GO:0005737	GO:0005829	GO:0006338	GO:0006351	GO:0006954	GO:0007399	GO:0008134	GO:0008270	GO:0008284	GO:0008285	GO:0010592	GO:0010832	GO:0010882	GO:0014894	GO:0014898	GO:0014911	GO:0016568	GO:0016575	GO:0017053	GO:0030018	GO:0030183	GO:0030955	GO:0031594	GO:0031672	GO:0032041	GO:0033235	GO:0033558	GO:0033613	GO:0034983	GO:0040029	GO:0042113	GO:0042493	GO:0042641	GO:0042826	GO:0043393	GO:0043433	GO:0043525	GO:0045668	GO:0045820	GO:0045892	GO:0045893	GO:0045944	GO:0048661	GO:0048742	GO:0051091	GO:0070491	GO:0070555	GO:0070932	GO:0070933	GO:0071260	GO:0071356	GO:0071374	GO:1903428																																																						
CHOYP_LOC100114171.1.1	O42254	m.50280	sp	IF2B1_CHICK	35.333	600	342	13	22	601	1	574	9.14E-106	333	IF2B1_CHICK	reviewed	Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2 mRNA-binding protein 1) (IMP-1) (IGF-II mRNA-binding protein 1) (VICKZ family member 1) (Zip-code binding polypeptide) (Zipcode-binding protein 1) (ZBP-1)	x	IGF2BP1 VICKZ1 ZBP1	Gallus gallus (Chicken)	576	CRD-mediated mRNA stabilization [GO:0070934]; mRNA transport [GO:0051028]; negative regulation of translation [GO:0017148]; neuronal stem cell population maintenance [GO:0097150]; pallium cell proliferation in forebrain [GO:0022013]; positive regulation of neuron projection development [GO:0010976]; regulation of mRNA stability involved in response to stress [GO:0010610]		0	0	0	PF00013;PF00076;	2706	m.50280	365245.2	211759.5455	573434.7059	582694.7857	1516110.75	917042.8333	1333250.333	482998.8462	1581996.059	366701.4286	1.440946903	0.643417737	GO:0000166	GO:0003729	GO:0003730	GO:0005634	GO:0010494	GO:0010610	GO:0010976	GO:0017148	GO:0022013	GO:0030027	GO:0030175	GO:0030426	GO:0045182	GO:0048027	GO:0048471	GO:0051028	GO:0070934	GO:0070937	GO:0097150																																																																																																			
CHOYP_LOC100174996.1.1	P42297	m.27300	sp	YXIE_BACSU	27.586	145	97	4	4	141	5	148	2.50E-09	55.5	YXIE_BACSU	reviewed	Universal stress protein YxiE (USP YxiE)	x	yxiE BSU39250 N17E	Bacillus subtilis (strain 168)	148	response to stress [GO:0006950]		0	0	0	PF00582;	2800	m.27300	15768	10356709	51504	92034	2104413.667	45672	14985274	31533	57969	138696	1.209082861	1.922524858	GO:0006950																																																																																																																					
CHOYP_LOC100177679.1.1	P74148	m.54177	sp	Y1388_SYNY3	28.824	170	104	6	11	180	2	154	2.95E-13	67.4	Y1388_SYNY3	reviewed	Universal stress protein Sll1388 (USP Sll1388)	x	sll1388	Synechocystis sp. (strain PCC 6803 / Kazusa)	154	response to stress [GO:0006950]		0	0	0	PF00582;	2812	m.54177	16813	149382	482708	31923	80985	808288	16392	2398202	1484143	203691	6.446108024	1.402272923	GO:0006950																																																																																																																					
CHOYP_LOC100180023.4.7	Q2FXL6	m.33650	sp	Y1819_STAA8	30.303	165	85	5	15	177	7	143	7.54E-10	58.2	Y1819_STAA8	reviewed	Putative universal stress protein SAOUHSC_01819	x	SAOUHSC_01819	Staphylococcus aureus (strain NCTC 8325)	166	response to stress [GO:0006950]		0	0	0	PF00582;	2822	m.33650	NA	68444	120155	211663	63945	3433784.5	22435	99430	13806	863883	7.640278583	2.049485734	GO:0005737	GO:0006950																																																																																																																				
CHOYP_LOC100180023.5.7	A0QZA1	m.56825	sp	Y3950_MYCS2	28.571	154	94	4	4	153	10	151	4.48E-10	59.7	Y3950_MYCS2	reviewed	Universal stress protein MSMEG_3950/MSMEI_3859 (USP MSMEG_3950)	x	MSMEG_3950 MSMEI_3859	Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)	294	response to stress [GO:0006950]		0	0	0	PF00582;	2823	m.56825	20097	103615	324919	NA	27665	NA	12744413	23790	20127.5	24708	26.9014195	2.696616574	GO:0006950																																																																																																																					
CHOYP_LOC100180023.6.7	P74897	m.63800	sp	YQA3_THEAQ	40.26	77	36	1	76	142	61	137	3.77E-08	52	YQA3_THEAQ	reviewed	Universal stress protein in QAH/OAS sulfhydrylase 3'region (USP)	x	0	Thermus aquaticus	137	response to stress [GO:0006950]		0	0	0	PF00582;	2824	m.63800	126517.5	1692581	562901.6667	444647.3333	27671.66667	19255766.75	118501.3333	1829603.333	367406	24992483.78	16.31343885	1.857172894	GO:0006950																																																																																																																					
CHOYP_LOC100180855.1.4	Q2FXL6	m.29179	sp	Y1819_STAA8	33.813	139	87	4	15	150	7	143	7.12E-12	62.8	Y1819_STAA8	reviewed	Putative universal stress protein SAOUHSC_01819	x	SAOUHSC_01819	Staphylococcus aureus (strain NCTC 8325)	166	response to stress [GO:0006950]		0	0	0	PF00582;	2831	m.29179	NA	68444	120155	211663	63945	3433784.5	22435	99430	13806	863883	7.640278583	2.049485734	GO:0005737	GO:0006950																																																																																																																				
CHOYP_LOC100180855.2.4	Q8LGG8	m.46097	sp	USPAL_ARATH	28.261	138	87	5	14	141	27	162	2.22E-11	61.6	USPAL_ARATH	reviewed	Universal stress protein A-like protein	x	At3g01520 F4P13.7	Arabidopsis thaliana (Mouse-ear cress)	175	response to stress [GO:0006950]		0	0	0	PF00582;	2832	m.46097	993920	202067.5	146146.5	298265	1299322.5	83000	1563098.333	370494	50451	321543	0.812521299	1.024429849	GO:0005886	GO:0006950	GO:0016208																																																																																																																			
CHOYP_LOC100181607.2.2	O07552	m.55285	sp	NHAX_BACSU	26.25	160	102	4	73	216	7	166	5.90E-09	56.6	NHAX_BACSU	reviewed	Stress response protein NhaX	x	nhaX yheK BSU09690	Bacillus subtilis (strain 168)	166	response to stress [GO:0006950]		0	0	0	PF00582;	2841	m.55285	494980	31084	64158.5	223025.3333	128777	205825.5	269893	22560	621286	133610.6667	1.330299502	0.903562525	GO:0006950																																																																																																																					
CHOYP_LOC100211409.1.1	P04792	m.4742	sp	HSPB1_HUMAN	38.667	75	43	2	161	233	95	168	3.82E-10	60.8	HSPB1_HUMAN	reviewed	Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27)	x	HSPB1 HSP27 HSP28	Homo sapiens (Human)	205	cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]		0	0	0	PF00011;	2894	m.4742	651414.5556	337618.1	6317623.786	378199.4438	467184	338760.75	3826765.727	2681237.5	1244984.25	2706129.875	1.324561491	1.051346873	GO:0000502	GO:0001895	GO:0005080	GO:0005615	GO:0005634	GO:0005737	GO:0005819	GO:0005829	GO:0005856	GO:0005886	GO:0005925	GO:0006446	GO:0006469	GO:0006928	GO:0006986	GO:0008426	GO:0009615	GO:0010506	GO:0019901	GO:0030018	GO:0031012	GO:0032731	GO:0035556	GO:0035924	GO:0038033	GO:0042535	GO:0042802	GO:0043066	GO:0043122	GO:0043130	GO:0043488	GO:0043536	GO:0044822	GO:0045766	GO:0048010	GO:0070062	GO:0070527	GO:1902176	GO:2001028																																																																															
CHOYP_LOC100371043.4.5	P00184	m.34262	sp	CP1A1_MOUSE	25.688	109	80	1	10	118	178	285	1.49E-06	49.3	CP1A1_MOUSE	reviewed	Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) (Cytochrome P450-P1)	x	Cyp1a1 Cyp1a-1	Mus musculus (Mouse)	524	9-cis-retinoic acid biosynthetic process [GO:0042904]; aging [GO:0007568]; amine metabolic process [GO:0009308]; camera-type eye development [GO:0043010]; cell proliferation [GO:0008283]; cellular response to organic cyclic compound [GO:0071407]; coumarin metabolic process [GO:0009804]; digestive tract development [GO:0048565]; drug metabolic process [GO:0017144]; embryo development ending in birth or egg hatching [GO:0009792]; flavonoid metabolic process [GO:0009812]; hepatocyte differentiation [GO:0070365]; heterocycle metabolic process [GO:0046483]; hydrogen peroxide biosynthetic process [GO:0050665]; insecticide metabolic process [GO:0017143]; maternal process involved in parturition [GO:0060137]; oxidation-reduction process [GO:0055114]; porphyrin-containing compound metabolic process [GO:0006778]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; response to antibiotic [GO:0046677]; response to arsenic-containing substance [GO:0046685]; response to drug [GO:0042493]; response to food [GO:0032094]; response to herbicide [GO:0009635]; response to hyperoxia [GO:0055093]; response to hypoxia [GO:0001666]; response to immobilization stress [GO:0035902]; response to iron(III) ion [GO:0010041]; response to lipopolysaccharide [GO:0032496]; response to nematode [GO:0009624]; response to toxic substance [GO:0009636]; response to virus [GO:0009615]; response to vitamin A [GO:0033189]; response to wounding [GO:0009611]; toxin metabolic process [GO:0009404]		0	0	0	PF00067;	3191	m.34263	186407	54401	1397167	260581.6667	22764.5	44155.5	298899.5	131393	65384.5	302437	0.438380378	1.476627112	GO:0001666	GO:0004497	GO:0005506	GO:0005739	GO:0005789	GO:0006778	GO:0007568	GO:0008283	GO:0008395	GO:0009308	GO:0009404	GO:0009611	GO:0009615	GO:0009624	GO:0009635	GO:0009636	GO:0009792	GO:0009804	GO:0009812	GO:0010041	GO:0016491	GO:0016679	GO:0016711	GO:0016712	GO:0017143	GO:0017144	GO:0020037	GO:0031090	GO:0032094	GO:0032451	GO:0032496	GO:0033189	GO:0035902	GO:0042493	GO:0042904	GO:0043010	GO:0043231	GO:0046483	GO:0046677	GO:0046685	GO:0048565	GO:0050665	GO:0055093	GO:0055114	GO:0060137	GO:0070330	GO:0070365	GO:0070576	GO:0071407	GO:1900087																																																																				
CHOYP_LOC100374573.1.1	P31689	m.24523	sp	DNJA1_HUMAN	65.594	404	125	5	1	398	1	396	4.75E-179	506	DNJA1_HUMAN	reviewed	DnaJ homolog subfamily A member 1 (DnaJ protein homolog 2) (HSDJ) (Heat shock 40 kDa protein 4) (Heat shock protein J2) (HSJ-2) (Human DnaJ protein 2) (hDj-2)	x	DNAJA1 DNAJ2 HDJ2 HSJ2 HSPF4	Homo sapiens (Human)	397	"androgen receptor signaling pathway [GO:0030521]; DNA damage response, detection of DNA damage [GO:0042769]; negative regulation of apoptotic process [GO:0043066]; negative regulation of establishment of protein localization to mitochondrion [GO:1903748]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway [GO:1905259]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of apoptotic process [GO:0043065]; protein folding [GO:0006457]; protein localization to mitochondrion [GO:0070585]; regulation of protein transport [GO:0051223]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; spermatogenesis [GO:0007283]; sperm motility [GO:0030317]; toxin transport [GO:1901998]"		0	0	cd06257;	PF00226;PF01556;PF00684;	3405	m.24523	309802.2	353796.6667	79159	386589.25	1288476.2	1920633.333	342487	276688	117232	4563791.667	2.986501102	1.445522413	GO:0001664	GO:0005524	GO:0005634	GO:0005739	GO:0005829	GO:0006457	GO:0006986	GO:0007283	GO:0009408	GO:0016020	GO:0030317	GO:0030521	GO:0030544	GO:0030957	GO:0031397	GO:0031625	GO:0042769	GO:0043065	GO:0043066	GO:0043508	GO:0046872	GO:0048471	GO:0050750	GO:0051087	GO:0051223	GO:0055131	GO:0070062	GO:0070585	GO:0098554	GO:1901998	GO:1903748	GO:1905259																																																																																						
CHOYP_LOC100377173.1.2	P04792	m.37699	sp	HSPB1_HUMAN	38.667	75	43	2	161	233	95	168	1.68E-09	59.3	HSPB1_HUMAN	reviewed	Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27)	x	HSPB1 HSP27 HSP28	Homo sapiens (Human)	205	cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]		0	0	0	PF00011;	3596	m.37698	2755969.8	72264.1	698586.8667	685428.0769	198614.6667	379931.6667	524564.4615	294265.0833	1047699.833	1460404.467	0.840394518	0.984186386	GO:0000502	GO:0001895	GO:0005080	GO:0005615	GO:0005634	GO:0005737	GO:0005819	GO:0005829	GO:0005856	GO:0005886	GO:0005925	GO:0006446	GO:0006469	GO:0006928	GO:0006986	GO:0008426	GO:0009615	GO:0010506	GO:0019901	GO:0030018	GO:0031012	GO:0032731	GO:0035556	GO:0035924	GO:0038033	GO:0042535	GO:0042802	GO:0043066	GO:0043122	GO:0043130	GO:0043488	GO:0043536	GO:0044822	GO:0045766	GO:0048010	GO:0070062	GO:0070527	GO:1902176	GO:2001028																																																																															
CHOYP_LOC589012.1.1	P16056	m.26892	sp	MET_MOUSE	27.807	748	441	24	42	731	635	1341	4.59E-74	266	MET_MOUSE	reviewed	Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)	x	Met	Mus musculus (Mouse)	1379	activation of MAPK activity [GO:0000187]; adult behavior [GO:0030534]; brain development [GO:0007420]; branching morphogenesis of an epithelial tube [GO:0048754]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; chemical synaptic transmission [GO:0007268]; endothelial cell morphogenesis [GO:0001886]; excitatory postsynaptic potential [GO:0060079]; glucose homeostasis [GO:0042593]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; liver development [GO:0001889]; modulation of synaptic transmission [GO:0050804]; muscle cell migration [GO:0014812]; muscle organ development [GO:0007517]; myoblast proliferation [GO:0051450]; myotube differentiation [GO:0014902]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-mediated programmed cell death [GO:1901299]; negative regulation of transforming growth factor beta production [GO:0071635]; placenta development [GO:0001890]; positive chemotaxis [GO:0050918]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of glucose transport [GO:0010828]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein autophosphorylation [GO:0046777]; reactive oxygen species metabolic process [GO:0072593]; regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling [GO:0060665]; regulation of cellular response to oxidative stress [GO:1900407]; regulation of interleukin-6 production [GO:0032675]; semaphorin-plexin signaling pathway [GO:0071526]; skeletal muscle tissue development [GO:0007519]		0	0	0	PF07714;PF01437;PF01403;PF01833;	4533	m.26892	59396	278817.25	441964.5	100422.4	75555	87041.5	1927668	49157	98312.25	69018.25	2.333509368	1.816442791	GO:0000187	GO:0001886	GO:0001889	GO:0001890	GO:0004672	GO:0005008	GO:0005524	GO:0007268	GO:0007420	GO:0007517	GO:0007519	GO:0009925	GO:0009986	GO:0010629	GO:0010828	GO:0014812	GO:0014902	GO:0016020	GO:0016021	GO:0019903	GO:0030534	GO:0032675	GO:0042593	GO:0045944	GO:0046777	GO:0048012	GO:0048754	GO:0050804	GO:0050918	GO:0051450	GO:0055013	GO:0060048	GO:0060079	GO:0060665	GO:0071526	GO:0071635	GO:0072593	GO:0098794	GO:1900407	GO:1900745	GO:1901299	GO:2001028																																																																												
CHOYP_MRP1.10.10	Q8CG09	m.64931	sp	MRP1_RAT	46.497	1570	782	19	4	1554	2	1532	0	1395	MRP1_RAT	reviewed	Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter)	x	Abcc1 Mrp1	Rattus norvegicus (Rat)	1532	cell chemotaxis [GO:0060326]; daunorubicin transport [GO:0043215]; drug export [GO:0046618]; drug transmembrane transport [GO:0006855]; glutathione transmembrane transport [GO:0034775]; negative regulation of neuron death [GO:1901215]; phospholipid efflux [GO:0033700]; plasma membrane long-chain fatty acid transport [GO:0015911]; positive regulation of cell migration [GO:0030335]; response to drug [GO:0042493]; response to oxidative stress [GO:0006979]; transmembrane transport [GO:0055085]; xenobiotic transport [GO:0042908]		0	0	0	PF00664;PF00005;	4871	m.64931	70780.33333	34651.66667	293493.5	50868.66667	44886.33333	142494	333917.6667	33090	172906.5	57362.4	1.495451239	0.898224035	GO:0005324	GO:0005524	GO:0005737	GO:0005886	GO:0005887	GO:0006855	GO:0006979	GO:0008559	GO:0015238	GO:0015431	GO:0015562	GO:0015911	GO:0016020	GO:0016323	GO:0016491	GO:0030335	GO:0033700	GO:0034040	GO:0034634	GO:0034775	GO:0042493	GO:0042908	GO:0043215	GO:0046618	GO:0046624	GO:0055085	GO:0060326	GO:1901215																																																																																										
CHOYP_RNP1B.1.1	P04792	m.59889	sp	HSPB1_HUMAN	36.145	83	52	1	46	127	89	171	9.52E-09	54.7	HSPB1_HUMAN	reviewed	Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27)	x	HSPB1 HSP27 HSP28	Homo sapiens (Human)	205	cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]		0	0	0	PF00011;	5723	m.59889	1996542	25739	171339.5	665833.5	17751	388418.5	80537.5	6428505	591267.3333	768276.25	2.869800582	1.758080064	GO:0000502	GO:0001895	GO:0005080	GO:0005615	GO:0005634	GO:0005737	GO:0005819	GO:0005829	GO:0005856	GO:0005886	GO:0005925	GO:0006446	GO:0006469	GO:0006928	GO:0006986	GO:0008426	GO:0009615	GO:0010506	GO:0019901	GO:0030018	GO:0031012	GO:0032731	GO:0035556	GO:0035924	GO:0038033	GO:0042535	GO:0042802	GO:0043066	GO:0043122	GO:0043130	GO:0043488	GO:0043536	GO:0044822	GO:0045766	GO:0048010	GO:0070062	GO:0070527	GO:1902176	GO:2001028																																																																															
CHOYP_SC31A.1.2	O57521	m.8241	sp	HS90B_DANRE	76.718	262	56	2	1	258	465	725	7.55E-140	412	HS90B_DANRE	reviewed	Heat shock protein HSP 90-beta	x	hsp90ab1 hsp90b	Danio rerio (Zebrafish) (Brachydanio rerio)	725	blood vessel development [GO:0001568]; leukocyte migration [GO:0050900]; muscle organ development [GO:0007517]; protein folding [GO:0006457]; response to estrogen [GO:0043627]; response to stress [GO:0006950]		0	0	0	PF02518;PF00183;	5990	m.8240	9164404.2	1361520.667	116619.3333	185248.3333	1829547	9327987.6	1016510.25	4068249	527168.6667	15804239.17	2.428958677	1.227667935	GO:0001568	GO:0005524	GO:0005634	GO:0005737	GO:0006457	GO:0006950	GO:0007517	GO:0043627	GO:0050900																																																																																																													
CHOYP_SMP_049250.1.1	P42930	m.1835	sp	HSPB1_RAT	32.71	107	70	2	15	119	67	173	5.31E-08	55.1	HSPB1_RAT	reviewed	Heat shock protein beta-1 (HspB1) (Heat shock 27 kDa protein) (HSP 27)	x	Hspb1 Hsp27	Rattus norvegicus (Rat)	206	aging [GO:0007568]; cellular response to butyrate [GO:1903545]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-11 [GO:0071348]; female pregnancy [GO:0007565]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced cell death [GO:1903202]; positive regulation of neuron projection development [GO:0010976]; response to angiotensin [GO:1990776]; response to ischemia [GO:0002931]; response to muscle stretch [GO:0035994]		0	0	0	PF00011;	6101	m.1835	150372	1061472	56760	1460974	15160	131588.5	1822599	21110	39365	431946	0.891381436	1.303305422	GO:0000502	GO:0002931	GO:0005634	GO:0005737	GO:0005819	GO:0005886	GO:0007565	GO:0007568	GO:0010976	GO:0030424	GO:0030425	GO:0031430	GO:0031674	GO:0035994	GO:0043066	GO:0043130	GO:0043204	GO:0045202	GO:0070301	GO:0071348	GO:0097512	GO:0098839	GO:1903202	GO:1903545	GO:1990776																																																																																													
CHOYP_SODM.1.2	P04179	m.45531	sp	SODM_HUMAN	63.182	220	79	2	6	224	2	220	3.23E-102	298	SODM_HUMAN	reviewed	"Superoxide dismutase [Mn], mitochondrial (EC 1.15.1.1)"	x	SOD2	Homo sapiens (Human)	222	age-dependent response to reactive oxygen species [GO:0001315]; negative regulation of cell proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; oxygen homeostasis [GO:0032364]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to reactive oxygen species [GO:0000302]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]; vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure [GO:0003069]		0	0	0	PF02777;PF00081;	6155	m.45530	78490.66667	205071	1617600.75	761757.5	19247.5	55224.5	179952	489340.6667	436601.75	183744	0.501409013	1.206078094	GO:0000302	GO:0000303	GO:0001315	GO:0001836	GO:0003069	GO:0004784	GO:0005739	GO:0005759	GO:0006357	GO:0006801	GO:0008217	GO:0008285	GO:0019430	GO:0030145	GO:0032364	GO:0042802	GO:0043524	GO:0051289	GO:0070062	GO:1902176																																																																																																		
CHOYP_STIP1.2.2	P31948	m.54723	sp	STIP1_HUMAN	52.065	557	243	5	24	576	7	543	0	551	STIP1_HUMAN	reviewed	Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (Renal carcinoma antigen NY-REN-11) (Transformation-sensitive protein IEF SSP 3521)	x	STIP1	Homo sapiens (Human)	543	response to stress [GO:0006950]		0	0	0	PF13414;PF07719;PF13181;	6204	m.54723	277224.5	239394.2857	564827.6	542207.6923	112510.4	1514133	336436.5833	1347760.615	276059.2143	9033543.176	7.204347714	1.90652305	GO:0005634	GO:0005794	GO:0006950	GO:0043209	GO:0043234	GO:0044822																																																																																																																
CHOYP_TRAP1.1.1	Q5XHZ0	m.60651	sp	TRAP1_RAT	60.777	566	216	4	13	574	143	706	0	720	TRAP1_RAT	reviewed	"Heat shock protein 75 kDa, mitochondrial (HSP 75) (TNFR-associated protein 1) (Tumor necrosis factor type 1 receptor-associated protein) (TRAP-1)"	x	Trap1 Hsp75	Rattus norvegicus (Rat)	706	negative regulation of cellular respiration [GO:1901856]; negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide [GO:1903751]; protein folding [GO:0006457]; response to stress [GO:0006950]; translational attenuation [GO:0009386]		0	0	0	PF00183;	6426	m.60651	580726.1818	659955.9333	270457.4545	147976.0667	1759394.467	2201730.882	3965564.308	237882.6429	877740.7222	1262641.474	2.499790778	0.990699714	GO:0005524	GO:0005654	GO:0005743	GO:0005758	GO:0005759	GO:0005811	GO:0006457	GO:0006950	GO:0009386	GO:0019901	GO:0044822	GO:0070062	GO:1901856	GO:1903751																																																																																																								
CHOYP_contig_012079	P74897	m.13840	sp	YQA3_THEAQ	30.612	147	88	4	4	150	3	135	9.77E-11	59.3	YQA3_THEAQ	reviewed	Universal stress protein in QAH/OAS sulfhydrylase 3'region (USP)	x	0	Thermus aquaticus	137	response to stress [GO:0006950]		0	0	0	PF00582;	1377	m.13839	NA	58863	32283	35933	28376	706159.6667	27690	30125	493471.25	54103	6.749471766	1.555452384	GO:0006950																																																																																																																					
CHOYP_contig_050645	Q08420	m.60289	sp	SODE_RAT	26.667	150	103	6	31	179	48	191	1.87E-09	58.9	SODE_RAT	reviewed	Extracellular superoxide dismutase [Cu-Zn] (EC-SOD) (EC 1.15.1.1) (Superoxide dismutase B)	x	Sod3 Sod-3	Rattus norvegicus (Rat)	244	response to copper ion [GO:0046688]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]; response to superoxide [GO:0000303]		0	0	cd00305;	PF00080;	1664	m.60289	149280	145904.5	715463.6	294631.5	178660.6667	579099.6667	494118	846515.83	402935	452613.6	1.870211463	0.566196417	GO:0000303	GO:0001666	GO:0004784	GO:0005507	GO:0005615	GO:0005634	GO:0005737	GO:0005802	GO:0006979	GO:0008270	GO:0031012	GO:0046688	GO:0070062																																																																																																									
																																																																																																																																																															
CHOYP_ARNT.1.1		m.19078	sp	ARNT_DROME	69.87	385	109	4	77	456	8	390	0	579	ARNT_DROME	reviewed	Aryl hydrocarbon receptor nuclear translocator homolog (dARNT) (Hypoxia-inducible factor 1-beta) (Protein tango)	x	tgo ARNT HIF-1-beta CG11987	Drosophila melanogaster (Fruit fly)	642	"brain development [GO:0007420]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; central nervous system development [GO:0007417]; dendrite morphogenesis [GO:0048813]; epithelial cell fate determination, open tracheal system [GO:0007425]; glial cell migration [GO:0008347]; limb development [GO:0060173]; muscle organ development [GO:0007517]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron development [GO:0048666]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; peripheral nervous system development [GO:0007422]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of R7 cell differentiation [GO:0045676]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription from RNA polymerase II promoter [GO:0006366]"	GO:0000122; GO:0000981; GO:0003700; GO:0005634; GO:0005667; GO:0005737; GO:0006355; GO:0006357; GO:0006366; GO:0007417; GO:0007420; GO:0007422; GO:0007424; GO:0007425; GO:0007517; GO:0008347; GO:0017022; GO:0032869; GO:0043234; GO:0043565; GO:0045676; GO:0045944; GO:0046982; GO:0048477; GO:0048666; GO:0048813; GO:0060173; GO:0071456	0	0	0	PF00010;PF00989;																																																																																																																																				
CHOYP_LOC411534.2.2		m.52136	sp	HIF1A_ONCMY	22.581	341	225	9	4	331	40	354	1.08E-17	91.3	HIF1A_ONCMY	reviewed	Hypoxia-inducible factor 1-alpha (HIF-1-alpha) (HIF1-alpha)	x	hif1a	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)	766	"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]"	GO:0003677; GO:0005623; GO:0005634; GO:0005737; GO:0006351; GO:0006355; GO:0016607	0	0	0	PF11413;PF08778;PF08447;PF13426;																																																																																																																																				
CHOYP_LOC101067536.1.1		m.63102	sp	HIF1A_ONCMY	40.708	565	273	14	7	516	12	569	1.78E-122	385	HIF1A_ONCMY	reviewed	Hypoxia-inducible factor 1-alpha (HIF-1-alpha) (HIF1-alpha)	x	hif1a	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)	766	"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]"	GO:0003677; GO:0005623; GO:0005634; GO:0005737; GO:0006351; GO:0006355; GO:0016607	0	0	0	PF11413;PF08778;PF08447;PF13426;																																																																																																																																				
CHOYP_HIF1N.1.1		m.53726	sp	HIF1N_HUMAN	57.862	318	131	2	20	334	32	349	5.70E-137	395	HIF1N_HUMAN	reviewed	Hypoxia-inducible factor 1-alpha inhibitor (EC 1.14.11.30) (EC 1.14.11.n4) (Factor inhibiting HIF-1) (FIH-1) (Hypoxia-inducible factor asparagine hydroxylase)	x	HIF1AN FIH1	Homo sapiens (Human)	349	"negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061428]; oxidation-reduction process [GO:0055114]; peptidyl-asparagine hydroxylation [GO:0042265]; peptidyl-aspartic acid hydroxylation [GO:0042264]; peptidyl-histidine hydroxylation [GO:0036138]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of vasculogenesis [GO:2001214]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; transcription, DNA-templated [GO:0006351]"	GO:0005112; GO:0005506; GO:0005654; GO:0005737; GO:0005829; GO:0006351; GO:0008270; GO:0016706; GO:0019826; GO:0031406; GO:0036138; GO:0036139; GO:0036140; GO:0042264; GO:0042265; GO:0042803; GO:0045663; GO:0045746; GO:0048037; GO:0048471; GO:0051059; GO:0055114; GO:0061418; GO:0061428; GO:0071532; GO:2001214	0	0	0	0