CHOYP_BRAFLDRAFT_114859.1.1	Q15119	m.37271	sp	PDK2_HUMAN	46.523	417	194	6	18	428	11	404	6.99E-132	389	PDK2_HUMAN	reviewed	"[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 2) (PDH kinase 2) (PDKII)"	PDK2 PDHK2	Homo sapiens (Human)	407	cellular response to nutrient [GO:0031670]; cellular response to reactive oxygen species [GO:0034614]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; insulin receptor signaling pathway [GO:0008286]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; regulation of acetyl-CoA biosynthetic process from pyruvate [GO:0010510]; regulation of cellular ketone metabolic process [GO:0010565]; regulation of gluconeogenesis [GO:0006111]; regulation of glucose metabolic process [GO:0010906]; regulation of pH [GO:0006885]	GO:0004672; GO:0004740; GO:0005524; GO:0005654; GO:0005737; GO:0005739; GO:0005759; GO:0005967; GO:0006006; GO:0006111; GO:0006885; GO:0008286; GO:0010510; GO:0010565; GO:0010906; GO:0031670; GO:0034614; GO:0042593; GO:0042803; GO:0072332	0	0	0	PF10436;PF02518;	412	m.37271	498683	162647	151645	2475057.5	266396	379961	325376.5	456311	361949	855889	0.669442781
CHOYP_LOC100371983.1.3	P9WK87	m.2863	sp	NLHH_MYCTU	34.286	245	148	5	85	320	54	294	1.22E-33	129	NLHH_MYCTU	reviewed	Carboxylesterase NlhH (EC 3.1.1.1)	nlhH lipH Rv1399c	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	319	catabolic process [GO:0009056]	GO:0009056; GO:0034338	0	0	0	PF07859;	3239	m.2863	133346.75	427847.625	900145.4667	352643.2857	209781.4	80202.5	99214.8	275870.75	586416.7143	601089.4286	0.811751649
CHOYP_LOC100371983.2.3	P9WK87	m.48879	sp	NLHH_MYCTU	33.878	245	149	6	60	295	54	294	7.64E-33	126	NLHH_MYCTU	reviewed	Carboxylesterase NlhH (EC 3.1.1.1)	nlhH lipH Rv1399c	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	319	catabolic process [GO:0009056]	GO:0009056; GO:0034338	0	0	0	PF07859;	3240	m.48879	133346.75	427847.625	900145.4667	352643.2857	209781.4	80202.5	99214.8	275870.75	586416.7143	601089.4286	0.811751649
CHOYP_LOC100371983.3.3	P9WK87	m.66662	sp	NLHH_MYCTU	34	150	95	3	57	206	51	196	1.15E-16	80.1	NLHH_MYCTU	reviewed	Carboxylesterase NlhH (EC 3.1.1.1)	nlhH lipH Rv1399c	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	319	catabolic process [GO:0009056]	GO:0009056; GO:0034338	0	0	0	PF07859;	3241	m.66662	105778	639015.8	900145.4667	354720.25	255530	58131.33333	99685	482151.5	646092.4	187098	0.653230348
CHOYP_LOC100375292.1.1	P50430	m.20844	sp	ARSB_RAT	41.509	477	236	7	19	457	34	505	3.04E-126	387	ARSB_RAT	reviewed	Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S)	Arsb	Rattus norvegicus (Rat)	528	autophagy [GO:0006914]; central nervous system development [GO:0007417]; colon epithelial cell migration [GO:0061580]; metabolic process [GO:0008152]; positive regulation of neuron projection development [GO:0010976]; regulation of epithelial cell migration [GO:0010632]; response to estrogen [GO:0043627]; response to methylmercury [GO:0051597]; response to nutrient [GO:0007584]; response to pH [GO:0009268]	GO:0003943; GO:0004065; GO:0005739; GO:0005764; GO:0005791; GO:0005794; GO:0006914; GO:0007417; GO:0007584; GO:0008152; GO:0008484; GO:0009268; GO:0009986; GO:0010632; GO:0010976; GO:0043627; GO:0046872; GO:0051597; GO:0061580; GO:0070062	0	0	0	PF00884;	3478	m.20844	443864	37788	324918	282229	407591	151821	650502	390779	2847279.25	315310	2.910799491
CHOYP_LOC100377677.2.2	P50430	m.27049	sp	ARSB_RAT	53.673	490	202	7	25	491	40	527	0	545	ARSB_RAT	reviewed	Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S)	Arsb	Rattus norvegicus (Rat)	528	autophagy [GO:0006914]; central nervous system development [GO:0007417]; colon epithelial cell migration [GO:0061580]; metabolic process [GO:0008152]; positive regulation of neuron projection development [GO:0010976]; regulation of epithelial cell migration [GO:0010632]; response to estrogen [GO:0043627]; response to methylmercury [GO:0051597]; response to nutrient [GO:0007584]; response to pH [GO:0009268]	GO:0003943; GO:0004065; GO:0005739; GO:0005764; GO:0005791; GO:0005794; GO:0006914; GO:0007417; GO:0007584; GO:0008152; GO:0008484; GO:0009268; GO:0009986; GO:0010632; GO:0010976; GO:0043627; GO:0046872; GO:0051597; GO:0061580; GO:0070062	0	0	0	PF00884;	3627	m.27049	206266	57516	7635236.667	172719	196721.5	404826	65956	23313	903772	377678	0.214737107
CHOYP_LOC100543859.1.1	Q99NH7	m.25074	sp	S26A5_MOUSE	32.271	722	411	9	14	731	36	683	3.29E-120	382	S26A5_MOUSE	reviewed	Prestin (Solute carrier family 26 member 5)	Slc26a5 Pres	Mus musculus (Mouse)	744	bicarbonate transport [GO:0015701]; chloride transmembrane transport [GO:1902476]; cochlea development [GO:0090102]; fructose transport [GO:0015755]; negative regulation of ion transmembrane transport [GO:0034766]; positive regulation of cell motility [GO:2000147]; positive regulation of cell size [GO:0045793]; protein tetramerization [GO:0051262]; regulation of cell shape [GO:0008360]; regulation of intracellular pH [GO:0051453]; regulation of membrane potential [GO:0042391]; response to auditory stimulus [GO:0010996]; response to drug [GO:0042493]; response to ischemia [GO:0002931]; response to potassium ion [GO:0035864]; response to salicylic acid [GO:0009751]; response to salt [GO:1902074]; response to thyroid hormone [GO:0097066]; sensory perception of sound [GO:0007605]	GO:0002931; GO:0005254; GO:0005737; GO:0005886; GO:0005887; GO:0007605; GO:0008271; GO:0008360; GO:0009751; GO:0010996; GO:0015106; GO:0015116; GO:0015301; GO:0015701; GO:0015755; GO:0016323; GO:0016328; GO:0019531; GO:0030507; GO:0034766; GO:0035864; GO:0042391; GO:0042493; GO:0045793; GO:0051262; GO:0051453; GO:0090102; GO:0097066; GO:1902074; GO:1902476; GO:2000147	0	0	0	PF01740;PF00916;	3782	m.25074	218410	1745636	83543	19009	15766	5134960	1142870	20150	392162	25274	3.224900162
CHOYP_LOC100898717.3.3	Q6AI14	m.37207	sp	SL9A4_HUMAN	41.152	243	140	2	5	247	14	253	1.93E-51	183	SL9A4_HUMAN	reviewed	Sodium/hydrogen exchanger 4 (Na(+)/H(+) exchanger 4) (NHE-4) (Solute carrier family 9 member 4)	SLC9A4 NHE4	Homo sapiens (Human)	798	epithelial cell development [GO:0002064]; gastric acid secretion [GO:0001696]; ion transport [GO:0006811]; potassium ion transmembrane transport [GO:0071805]; regulation of intracellular pH [GO:0051453]; sodium ion import across plasma membrane [GO:0098719]	GO:0001696; GO:0002064; GO:0005886; GO:0006811; GO:0015385; GO:0015386; GO:0016021; GO:0016323; GO:0016324; GO:0051453; GO:0071805; GO:0098719	0	0	0	PF00999;PF16644;	4153	m.37209	57475.5	54083.25	4954462	182535.3333	1057733.286	339644.5	146028.4	123970.75	695638.6667	202434	0.239081372
CHOYP_PPIH.1.1	O43447	m.18923	sp	PPIH_HUMAN	80.347	173	33	1	33	205	6	177	1.21E-101	294	PPIH_HUMAN	reviewed	Peptidyl-prolyl cis-trans isomerase H (PPIase H) (EC 5.2.1.8) (Rotamase H) (Small nuclear ribonucleoprotein particle-specific cyclophilin H) (CypH) (U-snRNP-associated cyclophilin SnuCyp-20) (USA-CYP)	PPIH CYP20 CYPH	Homo sapiens (Human)	177	"mRNA splicing, via spliceosome [GO:0000398]; positive regulation of viral genome replication [GO:0045070]; protein complex assembly [GO:0006461]; protein folding [GO:0006457]"	GO:0000398; GO:0003755; GO:0005654; GO:0005681; GO:0005737; GO:0006457; GO:0006461; GO:0016018; GO:0016607; GO:0043021; GO:0045070; GO:0046540; GO:0071001	0	0	0	PF00160;	5394	m.18923	209844.75	68743.75	192701	357724.6667	1351029.6	133420.5	101653.25	68793	248719.25	90439.8	0.294960042
CHOYP_RB11B.1.1	P22129	m.22118	sp	RB11B_DIPOM	58.411	214	77	2	1	202	1	214	2.56E-88	261	RB11B_DIPOM	reviewed	Ras-related protein Rab-11B (ORA3)	0	Diplobatis ommata (Ocellated electric ray) (Discopyge ommata)	218	"cellular response to acidic pH [GO:0071468]; constitutive secretory pathway [GO:0045054]; insulin secretion involved in cellular response to glucose stimulus [GO:0035773]; melanosome transport [GO:0032402]; receptor recycling [GO:0001881]; regulated exocytosis [GO:0045055]; regulation of anion transport [GO:0044070]; regulation of endocytic recycling [GO:2001135]; regulation of protein localization to cell surface [GO:2000008]; retrograde transport, endosome to plasma membrane [GO:1990126]; small GTPase mediated signal transduction [GO:0007264]; transferrin transport [GO:0033572]"	GO:0001881; GO:0003924; GO:0005525; GO:0007264; GO:0008021; GO:0019003; GO:0030054; GO:0030670; GO:0030672; GO:0032402; GO:0033572; GO:0035773; GO:0044070; GO:0045054; GO:0045055; GO:0045335; GO:0055038; GO:0071468; GO:1990126; GO:2000008; GO:2001135	0	0	0	PF00071;	5524	m.22118	879941.5	1367993	903330	NA	605610	48193	1131217	142999	92828	5624477.857	1.499057763
CHOYP_RS9.10.13	O43447	m.48533	sp	PPIH_HUMAN	79.339	121	24	1	1	121	58	177	4.50E-68	205	PPIH_HUMAN	reviewed	Peptidyl-prolyl cis-trans isomerase H (PPIase H) (EC 5.2.1.8) (Rotamase H) (Small nuclear ribonucleoprotein particle-specific cyclophilin H) (CypH) (U-snRNP-associated cyclophilin SnuCyp-20) (USA-CYP)	PPIH CYP20 CYPH	Homo sapiens (Human)	177	"mRNA splicing, via spliceosome [GO:0000398]; positive regulation of viral genome replication [GO:0045070]; protein complex assembly [GO:0006461]; protein folding [GO:0006457]"	GO:0000398; GO:0003755; GO:0005654; GO:0005681; GO:0005737; GO:0006457; GO:0006461; GO:0016018; GO:0016607; GO:0043021; GO:0045070; GO:0046540; GO:0071001	0	0	0	PF00160;	5927	m.48531	855930	112884672.8	212559371.3	106337.6667	46292413.67	12751110.25	40643218	33946765	2548879.25	10153462.67	0.268429775
CHOYP_RS9.10.13	O43447	m.48533	sp	PPIH_HUMAN	79.339	121	24	1	1	121	58	177	4.50E-68	205	PPIH_HUMAN	reviewed	Peptidyl-prolyl cis-trans isomerase H (PPIase H) (EC 5.2.1.8) (Rotamase H) (Small nuclear ribonucleoprotein particle-specific cyclophilin H) (CypH) (U-snRNP-associated cyclophilin SnuCyp-20) (USA-CYP)	PPIH CYP20 CYPH	Homo sapiens (Human)	177	"mRNA splicing, via spliceosome [GO:0000398]; positive regulation of viral genome replication [GO:0045070]; protein complex assembly [GO:0006461]; protein folding [GO:0006457]"	GO:0000398; GO:0003755; GO:0005654; GO:0005681; GO:0005737; GO:0006457; GO:0006461; GO:0016018; GO:0016607; GO:0043021; GO:0045070; GO:0046540; GO:0071001	0	0	0	PF00160;	5928	m.48533	209844.75	68743.75	192701	357724.6667	1351029.6	133420.5	101653.25	68793	248719.25	90439.8	0.294960042
CHOYP_RS9.11.13	O43447	m.49923	sp	PPIH_HUMAN	79.339	121	24	1	1	121	58	177	4.50E-68	205	PPIH_HUMAN	reviewed	Peptidyl-prolyl cis-trans isomerase H (PPIase H) (EC 5.2.1.8) (Rotamase H) (Small nuclear ribonucleoprotein particle-specific cyclophilin H) (CypH) (U-snRNP-associated cyclophilin SnuCyp-20) (USA-CYP)	PPIH CYP20 CYPH	Homo sapiens (Human)	177	"mRNA splicing, via spliceosome [GO:0000398]; positive regulation of viral genome replication [GO:0045070]; protein complex assembly [GO:0006461]; protein folding [GO:0006457]"	GO:0000398; GO:0003755; GO:0005654; GO:0005681; GO:0005737; GO:0006457; GO:0006461; GO:0016018; GO:0016607; GO:0043021; GO:0045070; GO:0046540; GO:0071001	0	0	0	PF00160;	5929	m.49921	855930	112884672.8	212559371.3	106337.6667	46292413.67	12751110.25	40643218	33946765	2548879.25	10153462.67	0.268429775
CHOYP_RS9.11.13	O43447	m.49923	sp	PPIH_HUMAN	79.339	121	24	1	1	121	58	177	4.50E-68	205	PPIH_HUMAN	reviewed	Peptidyl-prolyl cis-trans isomerase H (PPIase H) (EC 5.2.1.8) (Rotamase H) (Small nuclear ribonucleoprotein particle-specific cyclophilin H) (CypH) (U-snRNP-associated cyclophilin SnuCyp-20) (USA-CYP)	PPIH CYP20 CYPH	Homo sapiens (Human)	177	"mRNA splicing, via spliceosome [GO:0000398]; positive regulation of viral genome replication [GO:0045070]; protein complex assembly [GO:0006461]; protein folding [GO:0006457]"	GO:0000398; GO:0003755; GO:0005654; GO:0005681; GO:0005737; GO:0006457; GO:0006461; GO:0016018; GO:0016607; GO:0043021; GO:0045070; GO:0046540; GO:0071001	0	0	0	PF00160;	5930	m.49923	209844.75	68743.75	192701	357724.6667	1351029.6	133420.5	101653.25	68793	248719.25	90439.8	0.294960042
CHOYP_S26A5.2.2	P58743	m.9883	sp	S26A5_HUMAN	31.893	787	456	18	38	813	17	734	1.75E-128	405	S26A5_HUMAN	reviewed	Prestin (Solute carrier family 26 member 5)	SLC26A5 PRES	Homo sapiens (Human)	744	bicarbonate transport [GO:0015701]; chloride transmembrane transport [GO:1902476]; cochlea development [GO:0090102]; fructose transport [GO:0015755]; negative regulation of ion transmembrane transport [GO:0034766]; positive regulation of cell motility [GO:2000147]; positive regulation of cell size [GO:0045793]; protein tetramerization [GO:0051262]; regulation of cell shape [GO:0008360]; regulation of intracellular pH [GO:0051453]; regulation of membrane potential [GO:0042391]; response to auditory stimulus [GO:0010996]; response to drug [GO:0042493]; response to ischemia [GO:0002931]; response to potassium ion [GO:0035864]; response to salicylic acid [GO:0009751]; response to salt [GO:1902074]; response to thyroid hormone [GO:0097066]; sensory perception of sound [GO:0007605]	GO:0002931; GO:0005254; GO:0005737; GO:0005887; GO:0007605; GO:0008271; GO:0008360; GO:0009751; GO:0010996; GO:0015106; GO:0015116; GO:0015301; GO:0015701; GO:0015755; GO:0016323; GO:0016328; GO:0019531; GO:0034766; GO:0035864; GO:0042391; GO:0042493; GO:0045793; GO:0051262; GO:0051453; GO:0090102; GO:0097066; GO:1902074; GO:1902476; GO:2000147	0	0	0	PF01740;PF00916;	5963	m.9883	379891.9091	982219	334708	386745.8	182057.7143	1421679.625	427219.375	226192.1429	4036022.75	360711.2143	2.856532951
CHOYP_S4A10.3.4	Q8JZR6	m.28397	sp	S4A8_MOUSE	48	1100	504	22	6	1069	19	1086	0	986	S4A8_MOUSE	reviewed	Electroneutral sodium bicarbonate exchanger 1 (Electroneutral Na+-driven Cl-HCO3 exchanger) (Solute carrier family 4 member 8) (k-NBC3)	Slc4a8 Kiaa0739	Mus musculus (Mouse)	1089	anion transmembrane transport [GO:0098656]; bicarbonate transport [GO:0015701]; regulation of intracellular pH [GO:0051453]; sodium ion transport [GO:0006814]	GO:0005452; GO:0005886; GO:0005887; GO:0006814; GO:0008509; GO:0015301; GO:0015701; GO:0016020; GO:0032809; GO:0043005; GO:0051453; GO:0098656	0	0	0	PF07565;PF00955;	5966	m.28397	247875.4444	485743.0952	545415.75	2450002	606938.1667	1797841.455	642519.375	564532.6364	862307	4129405.032	1.84424645
CHOYP_SL9A7.1.2	Q8BZ00	m.40514	sp	SL9A9_MOUSE	51.661	602	251	12	72	656	30	608	0	587	SL9A9_MOUSE	reviewed	Sodium/hydrogen exchanger 9 (Na(+)/H(+) exchanger 9) (NHE-9) (Solute carrier family 9 member 9)	Slc9a9 Nhe9	Mus musculus (Mouse)	644	regulation of pH [GO:0006885]	GO:0006885; GO:0015385; GO:0016021; GO:0031902; GO:0055037	0	0	0	PF00999;	6070	m.40514	196853	373755	1319347	139011	119418	148746	383577.5	159994	1333870	37343	0.960503569
CHOYP_SL9A7.2.2	Q8BZ00	m.45572	sp	SL9A9_MOUSE	50	620	256	12	81	687	30	608	0	583	SL9A9_MOUSE	reviewed	Sodium/hydrogen exchanger 9 (Na(+)/H(+) exchanger 9) (NHE-9) (Solute carrier family 9 member 9)	Slc9a9 Nhe9	Mus musculus (Mouse)	644	regulation of pH [GO:0006885]	GO:0006885; GO:0015385; GO:0016021; GO:0031902; GO:0055037	0	0	0	PF00999;	6071	m.45572	196853	373755	1319347	139011	119418	148746	383577.5	159994	1333870	37343	0.960503569