CHOYP_14332.1.2	P62325	m.5644	sp	BTG1_MOUSE	47.205	161	80	2	1	156	11	171	2.18E-47	155	BTG1_MOUSE	reviewed	Protein BTG1 (B-cell translocation gene 1 protein)	Btg1	Mus musculus (Mouse)	171	negative regulation of cell proliferation [GO:0008285]; positive regulation of angiogenesis [GO:0045766]; positive regulation of catalytic activity [GO:0043085]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of fibroblast apoptotic process [GO:2000271]; positive regulation of myoblast differentiation [GO:0045663]; protein methylation [GO:0006479]; response to oxidative stress [GO:0006979]; response to peptide hormone [GO:0043434]; spermatogenesis [GO:0007283]	GO:0005634; GO:0005737; GO:0006479; GO:0006979; GO:0007283; GO:0008285; GO:0019899; GO:0043085; GO:0043434; GO:0045603; GO:0045663; GO:0045766; GO:2000271	0	0	0	PF07742;	1	m.5643	3293219.556	1726699.5	2716275.545	13976900.44	2243615.1	4909780.357	3073463.222	1943599.9	5308420.417	1708631.273	0.707271369
CHOYP_ACT.9.27	P62325	m.24631	sp	BTG1_MOUSE	47.205	161	80	2	1	156	11	171	2.18E-47	155	BTG1_MOUSE	reviewed	Protein BTG1 (B-cell translocation gene 1 protein)	Btg1	Mus musculus (Mouse)	171	negative regulation of cell proliferation [GO:0008285]; positive regulation of angiogenesis [GO:0045766]; positive regulation of catalytic activity [GO:0043085]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of fibroblast apoptotic process [GO:2000271]; positive regulation of myoblast differentiation [GO:0045663]; protein methylation [GO:0006479]; response to oxidative stress [GO:0006979]; response to peptide hormone [GO:0043434]; spermatogenesis [GO:0007283]	GO:0005634; GO:0005737; GO:0006479; GO:0006979; GO:0007283; GO:0008285; GO:0019899; GO:0043085; GO:0043434; GO:0045603; GO:0045663; GO:0045766; GO:2000271	0	0	0	PF07742;	131	m.24629	6945383.727	302723107.2	72394162.85	210980052.5	181571192.2	372065.8571	298992616.5	25577198.86	1416715827	1617153.444	2.250508111
CHOYP_ACT.9.27	P62325	m.24631	sp	BTG1_MOUSE	47.205	161	80	2	1	156	11	171	2.18E-47	155	BTG1_MOUSE	reviewed	Protein BTG1 (B-cell translocation gene 1 protein)	Btg1	Mus musculus (Mouse)	171	negative regulation of cell proliferation [GO:0008285]; positive regulation of angiogenesis [GO:0045766]; positive regulation of catalytic activity [GO:0043085]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of fibroblast apoptotic process [GO:2000271]; positive regulation of myoblast differentiation [GO:0045663]; protein methylation [GO:0006479]; response to oxidative stress [GO:0006979]; response to peptide hormone [GO:0043434]; spermatogenesis [GO:0007283]	GO:0005634; GO:0005737; GO:0006479; GO:0006979; GO:0007283; GO:0008285; GO:0019899; GO:0043085; GO:0043434; GO:0045603; GO:0045663; GO:0045766; GO:2000271	0	0	0	PF07742;	132	m.24630	1220132	180739.9231	1041195.892	383632.1667	641262.9	740840.3636	378081.2308	562590.6222	358103.0769	2347862.5	1.265510461
CHOYP_AKT1.1.2	Q8INB9	m.23291	sp	AKT1_DROME	81.224	245	46	0	1	245	323	567	5.96E-151	437	AKT1_DROME	reviewed	RAC serine/threonine-protein kinase (DAkt) (DRAC-PK) (Dakt1) (EC 2.7.11.1) (Akt) (Protein kinase B) (PKB)	Akt1 CG4006	Drosophila melanogaster (Fruit fly)	611	"apoptotic process [GO:0006915]; chitin-based embryonic cuticle biosynthetic process [GO:0008362]; circadian rhythm [GO:0007623]; dendrite regeneration [GO:0031104]; epithelial cell migration, open tracheal system [GO:0007427]; insulin receptor signaling pathway [GO:0008286]; intracellular signal transduction [GO:0035556]; lipid metabolic process [GO:0006629]; lipid storage [GO:0019915]; long term synaptic depression [GO:0060292]; multicellular organism growth [GO:0035264]; myoblast fusion [GO:0007520]; negative regulation of apoptotic process [GO:0043066]; negative regulation of neuron death [GO:1901215]; negative regulation of peptide hormone secretion [GO:0090278]; negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of axon regeneration [GO:0048680]; positive regulation of cell growth [GO:0030307]; positive regulation of cell size [GO:0045793]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of organ growth [GO:0046622]; protein phosphorylation [GO:0006468]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of dendrite development [GO:0050773]; regulation of glucose metabolic process [GO:0010906]; regulation of hemocyte proliferation [GO:0035206]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein import into nucleus [GO:0042306]; response to oxidative stress [GO:0006979]; somatic muscle development [GO:0007525]"	GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006468; GO:0006629; GO:0006915; GO:0006979; GO:0007424; GO:0007427; GO:0007520; GO:0007525; GO:0007623; GO:0008286; GO:0008360; GO:0008361; GO:0008362; GO:0009986; GO:0010906; GO:0018105; GO:0019915; GO:0030307; GO:0031104; GO:0035091; GO:0035206; GO:0035264; GO:0035556; GO:0040014; GO:0040018; GO:0042306; GO:0043025; GO:0043066; GO:0045793; GO:0045886; GO:0046620; GO:0046622; GO:0048477; GO:0048680; GO:0050773; GO:0060292; GO:0090278; GO:1901215	0	0	0	PF00169;PF00069;PF00433;	228	m.23291	101574	NA	42517	131933	83082	101967	113421	56333	337843.5	194345	1.790912989
CHOYP_AKT1.2.2	Q8INB9	m.51125	sp	AKT1_DROME	63.2	500	139	5	10	474	107	596	0	639	AKT1_DROME	reviewed	RAC serine/threonine-protein kinase (DAkt) (DRAC-PK) (Dakt1) (EC 2.7.11.1) (Akt) (Protein kinase B) (PKB)	Akt1 CG4006	Drosophila melanogaster (Fruit fly)	611	"apoptotic process [GO:0006915]; chitin-based embryonic cuticle biosynthetic process [GO:0008362]; circadian rhythm [GO:0007623]; dendrite regeneration [GO:0031104]; epithelial cell migration, open tracheal system [GO:0007427]; insulin receptor signaling pathway [GO:0008286]; intracellular signal transduction [GO:0035556]; lipid metabolic process [GO:0006629]; lipid storage [GO:0019915]; long term synaptic depression [GO:0060292]; multicellular organism growth [GO:0035264]; myoblast fusion [GO:0007520]; negative regulation of apoptotic process [GO:0043066]; negative regulation of neuron death [GO:1901215]; negative regulation of peptide hormone secretion [GO:0090278]; negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of axon regeneration [GO:0048680]; positive regulation of cell growth [GO:0030307]; positive regulation of cell size [GO:0045793]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of organ growth [GO:0046622]; protein phosphorylation [GO:0006468]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of dendrite development [GO:0050773]; regulation of glucose metabolic process [GO:0010906]; regulation of hemocyte proliferation [GO:0035206]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein import into nucleus [GO:0042306]; response to oxidative stress [GO:0006979]; somatic muscle development [GO:0007525]"	GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006468; GO:0006629; GO:0006915; GO:0006979; GO:0007424; GO:0007427; GO:0007520; GO:0007525; GO:0007623; GO:0008286; GO:0008360; GO:0008361; GO:0008362; GO:0009986; GO:0010906; GO:0018105; GO:0019915; GO:0030307; GO:0031104; GO:0035091; GO:0035206; GO:0035264; GO:0035556; GO:0040014; GO:0040018; GO:0042306; GO:0043025; GO:0043066; GO:0045793; GO:0045886; GO:0046620; GO:0046622; GO:0048477; GO:0048680; GO:0050773; GO:0060292; GO:0090278; GO:1901215	0	0	0	PF00169;PF00069;PF00433;	229	m.51125	101574	NA	42517	131933	83082	101967	113421	56333	337843.5	194345	1.790912989
CHOYP_BRAFLDRAFT_113892.1.1	P48508	m.44055	sp	GSH0_RAT	37.5	256	159	1	12	266	16	271	5.47E-65	207	GSH0_RAT	reviewed	Glutamate--cysteine ligase regulatory subunit (GCS light chain) (Gamma-ECS regulatory subunit) (Gamma-glutamylcysteine synthetase regulatory subunit) (Glutamate--cysteine ligase modifier subunit)	Gclm Glclr	Rattus norvegicus (Rat)	274	aging [GO:0007568]; apoptotic mitochondrial changes [GO:0008637]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to glucose stimulus [GO:0071333]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to thyroxine stimulus [GO:0097069]; cysteine metabolic process [GO:0006534]; glutamate metabolic process [GO:0006536]; glutathione biosynthetic process [GO:0006750]; hepatic stellate cell activation [GO:0035733]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of glutamate-cysteine ligase activity [GO:0035229]; regulation of blood vessel size [GO:0050880]; regulation of mitochondrial depolarization [GO:0051900]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to human chorionic gonadotropin [GO:0044752]; response to nitrosative stress [GO:0051409]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]	GO:0004357; GO:0006534; GO:0006536; GO:0006750; GO:0006979; GO:0007568; GO:0007584; GO:0008637; GO:0014823; GO:0017109; GO:0030234; GO:0035226; GO:0035229; GO:0035729; GO:0035733; GO:0042493; GO:0043524; GO:0044344; GO:0044752; GO:0046982; GO:0050880; GO:0051409; GO:0051900; GO:0071333; GO:0071372; GO:0097069; GO:2001237	PATHWAY: Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 1/2.	0	0	PF00248;	394	m.44055	81002	124806	256648	185693.25	75789.66667	67788.5	101137	52280	471324	104628.3333	1.101139633
CHOYP_BRAFLDRAFT_119799.1.1	P30044	m.23765	sp	PRDX5_HUMAN	59.524	168	66	1	18	183	43	210	7.18E-69	211	PRDX5_HUMAN	reviewed	"Peroxiredoxin-5, mitochondrial (EC 1.11.1.15) (Alu corepressor 1) (Antioxidant enzyme B166) (AOEB166) (Liver tissue 2D-page spot 71B) (PLP) (Peroxiredoxin V) (Prx-V) (Peroxisomal antioxidant enzyme) (TPx type VI) (Thioredoxin peroxidase PMP20) (Thioredoxin reductase)"	PRDX5 ACR1 SBBI10	Homo sapiens (Human)	214	cell redox homeostasis [GO:0045454]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; inflammatory response [GO:0006954]; NADPH oxidation [GO:0070995]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of transcription from RNA polymerase III promoter [GO:0016480]; positive regulation of collagen biosynthetic process [GO:0032967]; reactive nitrogen species metabolic process [GO:2001057]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; response to oxidative stress [GO:0006979]; response to reactive oxygen species [GO:0000302]	GO:0000302; GO:0001016; GO:0004601; GO:0005102; GO:0005615; GO:0005634; GO:0005737; GO:0005739; GO:0005759; GO:0005777; GO:0005782; GO:0005829; GO:0006954; GO:0006979; GO:0008379; GO:0016209; GO:0016480; GO:0031410; GO:0032967; GO:0034614; GO:0042744; GO:0043027; GO:0043066; GO:0043231; GO:0045454; GO:0046983; GO:0048471; GO:0051354; GO:0051920; GO:0060785; GO:0070062; GO:0070995; GO:0072541; GO:2001057	0	0	0	PF08534;	478	m.23765	23982944.17	13890076.81	4635772	2601289.75	17147594.83	1161584.636	5768779.182	967580.7	5408679.8	31874359.25	0.725709428
CHOYP_BRAFLDRAFT_203655.1.2	P09874	m.12	sp	PARP1_HUMAN	42.609	115	60	2	1	114	696	805	3.08E-23	96.3	PARP1_HUMAN	reviewed	Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 1) (ARTD1) (NAD(+) ADP-ribosyltransferase 1) (ADPRT 1) (Poly[ADP-ribose] synthase 1)	PARP1 ADPRT PPOL	Homo sapiens (Human)	1014	"ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; DNA damage response, detection of DNA damage [GO:0042769]; DNA ligation involved in DNA repair [GO:0051103]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; lagging strand elongation [GO:0006273]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of SMAD protein import into nucleus [GO:0060391]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; protein sumoylation [GO:0016925]; regulation of cellular protein localization [GO:1903827]; signal transduction involved in regulation of gene expression [GO:0023019]; transcription from RNA polymerase II promoter [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]"	GO:0000122; GO:0000715; GO:0000717; GO:0000724; GO:0000784; GO:0003677; GO:0003910; GO:0003950; GO:0005634; GO:0005635; GO:0005654; GO:0005667; GO:0005730; GO:0005739; GO:0006273; GO:0006281; GO:0006293; GO:0006294; GO:0006295; GO:0006296; GO:0006302; GO:0006366; GO:0006471; GO:0006974; GO:0007005; GO:0007179; GO:0008134; GO:0008270; GO:0010613; GO:0016020; GO:0016540; GO:0016925; GO:0019899; GO:0019901; GO:0023019; GO:0030225; GO:0032042; GO:0032869; GO:0033683; GO:0034599; GO:0036211; GO:0042769; GO:0042802; GO:0043234; GO:0043504; GO:0044822; GO:0045944; GO:0047485; GO:0051103; GO:0051287; GO:0060391; GO:0070212; GO:0070911; GO:1903827; GO:1904357; GO:1990966; GO:2000679	0	0	0	PF00533;PF08063;PF00644;PF02877;PF05406;PF00645;	623	m.12	68866	17367	17733	124245.5	212698.5	229406.6667	17093	57229	76547.66667	73861.33333	1.030000832
CHOYP_BRAFLDRAFT_61845.1.1	P56597	m.37831	sp	NDK5_HUMAN	67.839	199	64	0	17	215	4	202	3.66E-107	310	NDK5_HUMAN	reviewed	Nucleoside diphosphate kinase homolog 5 (NDK-H 5) (NDP kinase homolog 5) (Inhibitor of p53-induced apoptosis-beta) (IPIA-beta) (Testis-specific nm23 homolog) (nm23-H5)	NME5	Homo sapiens (Human)	212	cilium assembly [GO:0042384]; CTP biosynthetic process [GO:0006241]; epithelial cilium movement [GO:0003351]; GTP biosynthetic process [GO:0006183]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; nucleoside metabolic process [GO:0009116]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]; UTP biosynthetic process [GO:0006228]; ventricular system development [GO:0021591]	GO:0003351; GO:0004550; GO:0005622; GO:0006183; GO:0006228; GO:0006241; GO:0007283; GO:0007286; GO:0009116; GO:0021591; GO:0036126; GO:0042384; GO:1902176	0	0	0	PF05186;PF00334;	852	m.37831	288598.5	29334	192991	650690	71418	159705	153020	1577694	598702	3769738.143	5.075992903
CHOYP_CATA.1.3	Q9PWF7	m.11120	sp	CATA_RUGRU	66.794	262	86	1	44	305	238	498	1.91E-124	369	CATA_RUGRU	reviewed	Catalase (EC 1.11.1.6)	cat	Rugosa rugosa (Japanese wrinkled frog) (Glandirana rugosa)	528	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	GO:0004096; GO:0005777; GO:0006979; GO:0020037; GO:0042744; GO:0046872	0	0	0	PF00199;PF06628;	1164	m.11120	217389.2857	189117.2222	414395.2	616062.8462	733193.4286	391679.2727	255387.3	239523.8333	424081.4	375916.75	0.777173169
CHOYP_CATA.2.3	Q9PWF7	m.18456	sp	CATA_RUGRU	62	150	56	1	1	150	350	498	4.98E-58	192	CATA_RUGRU	reviewed	Catalase (EC 1.11.1.6)	cat	Rugosa rugosa (Japanese wrinkled frog) (Glandirana rugosa)	528	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	GO:0004096; GO:0005777; GO:0006979; GO:0020037; GO:0042744; GO:0046872	0	0	0	PF00199;PF06628;	1165	m.18454	564396.7647	367283.6364	705840.0714	416959.6667	404097.5455	522593.3125	440098.7778	395214.6923	1367748.25	818153.3125	1.441405886
CHOYP_CATA.2.3	Q9PWF7	m.18456	sp	CATA_RUGRU	62	150	56	1	1	150	350	498	4.98E-58	192	CATA_RUGRU	reviewed	Catalase (EC 1.11.1.6)	cat	Rugosa rugosa (Japanese wrinkled frog) (Glandirana rugosa)	528	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	GO:0004096; GO:0005777; GO:0006979; GO:0020037; GO:0042744; GO:0046872	0	0	0	PF00199;PF06628;	1166	m.18456	59230.66667	218247.6667	549006.5	1407834.8	2466046.5	1077172.333	152714.6667	51178	83431	301492.6667	0.354438063
CHOYP_CATA.3.3	Q9PWF7	m.21642	sp	CATA_RUGRU	69.293	495	149	2	4	496	5	498	0	731	CATA_RUGRU	reviewed	Catalase (EC 1.11.1.6)	cat	Rugosa rugosa (Japanese wrinkled frog) (Glandirana rugosa)	528	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	GO:0004096; GO:0005777; GO:0006979; GO:0020037; GO:0042744; GO:0046872	0	0	0	PF00199;PF06628;	1167	m.21642	539767.45	313699.1765	367464.8696	950809.8889	538571.2	399029.9474	247616.3571	240972.5882	1029219.842	338429.12	0.832106181
CHOYP_CRYAB.2.5	P04792	m.23200	sp	HSPB1_HUMAN	37.234	94	57	2	46	138	89	181	2.28E-09	58.5	HSPB1_HUMAN	reviewed	Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27)	HSPB1 HSP27 HSP28	Homo sapiens (Human)	205	cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028	0	0	0	PF00011;	1763	m.23200	656032.1667	491253.6667	589739.5	275663.5	539560.6667	427730.8333	123881.8333	3278779.125	1646641	558611.7	2.364833254
CHOYP_CRYAB.2.5	P04792	m.23200	sp	HSPB1_HUMAN	37.234	94	57	2	46	138	89	181	2.28E-09	58.5	HSPB1_HUMAN	reviewed	Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27)	HSPB1 HSP27 HSP28	Homo sapiens (Human)	205	cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028	0	0	0	PF00011;	1764	m.23201	483273.625	372271.3333	7342004.5	286184.5	542089.5	246745.6667	4659260.889	1075265.714	1637214.4	3352081.083	1.215464473
CHOYP_CRYAB.2.5	P04792	m.23201	sp	HSPB1_HUMAN	38.667	75	43	2	49	121	95	168	3.24E-11	61.2	HSPB1_HUMAN	reviewed	Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27)	HSPB1 HSP27 HSP28	Homo sapiens (Human)	205	cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028	0	0	0	PF00011;	1763	m.23200	656032.1667	491253.6667	589739.5	275663.5	539560.6667	427730.8333	123881.8333	3278779.125	1646641	558611.7	2.364833254
CHOYP_CRYAB.2.5	P04792	m.23201	sp	HSPB1_HUMAN	38.667	75	43	2	49	121	95	168	3.24E-11	61.2	HSPB1_HUMAN	reviewed	Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27)	HSPB1 HSP27 HSP28	Homo sapiens (Human)	205	cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028	0	0	0	PF00011;	1764	m.23201	483273.625	372271.3333	7342004.5	286184.5	542089.5	246745.6667	4659260.889	1075265.714	1637214.4	3352081.083	1.215464473
CHOYP_CYT5.1.1	P14841	m.29962	sp	CYTC_RAT	30.208	96	63	2	3	95	35	129	9.33E-06	44.7	CYTC_RAT	reviewed	Cystatin-C (Cystatin-3)	Cst3	Rattus norvegicus (Rat)	140	"apoptotic process [GO:0006915]; brain development [GO:0007420]; cell activation [GO:0001775]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to oxidative stress [GO:0034599]; circadian sleep/wake cycle, REM sleep [GO:0042747]; embryo implantation [GO:0007566]; eye development [GO:0001654]; male gonad development [GO:0008584]; negative regulation of cell death [GO:0060548]; positive regulation of cell proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; regulation of programmed cell death [GO:0043067]; response to axon injury [GO:0048678]; response to carbohydrate [GO:0009743]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to inorganic substance [GO:0010035]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; salivary gland development [GO:0007431]; Sertoli cell development [GO:0060009]"	GO:0001654; GO:0001666; GO:0001775; GO:0002020; GO:0004869; GO:0005604; GO:0005615; GO:0005737; GO:0005764; GO:0005771; GO:0005783; GO:0006915; GO:0006979; GO:0007420; GO:0007431; GO:0007566; GO:0008284; GO:0008584; GO:0009636; GO:0009743; GO:0010035; GO:0014070; GO:0030414; GO:0030424; GO:0031667; GO:0031965; GO:0031982; GO:0032355; GO:0034599; GO:0042493; GO:0042747; GO:0042995; GO:0043025; GO:0043067; GO:0043292; GO:0045740; GO:0048471; GO:0048678; GO:0060009; GO:0060548; GO:0070301	0	0	0	PF00031;	1802	m.29960	66898.8	126269.5	64611	712184.25	326682.45	417565.75	530142	295340.6667	1428826.833	764116	2.649906952
CHOYP_CYT5.1.1	P14841	m.29962	sp	CYTC_RAT	30.208	96	63	2	3	95	35	129	9.33E-06	44.7	CYTC_RAT	reviewed	Cystatin-C (Cystatin-3)	Cst3	Rattus norvegicus (Rat)	140	"apoptotic process [GO:0006915]; brain development [GO:0007420]; cell activation [GO:0001775]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to oxidative stress [GO:0034599]; circadian sleep/wake cycle, REM sleep [GO:0042747]; embryo implantation [GO:0007566]; eye development [GO:0001654]; male gonad development [GO:0008584]; negative regulation of cell death [GO:0060548]; positive regulation of cell proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; regulation of programmed cell death [GO:0043067]; response to axon injury [GO:0048678]; response to carbohydrate [GO:0009743]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to inorganic substance [GO:0010035]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; salivary gland development [GO:0007431]; Sertoli cell development [GO:0060009]"	GO:0001654; GO:0001666; GO:0001775; GO:0002020; GO:0004869; GO:0005604; GO:0005615; GO:0005737; GO:0005764; GO:0005771; GO:0005783; GO:0006915; GO:0006979; GO:0007420; GO:0007431; GO:0007566; GO:0008284; GO:0008584; GO:0009636; GO:0009743; GO:0010035; GO:0014070; GO:0030414; GO:0030424; GO:0031667; GO:0031965; GO:0031982; GO:0032355; GO:0034599; GO:0042493; GO:0042747; GO:0042995; GO:0043025; GO:0043067; GO:0043292; GO:0045740; GO:0048471; GO:0048678; GO:0060009; GO:0060548; GO:0070301	0	0	0	PF00031;	1803	m.29962	183189	92815	172106	157191	244696	60465	108336	236467	107114	716706.5	1.445991574
CHOYP_DPER_GL22446.1.1	P04792	m.52315	sp	HSPB1_HUMAN	37.838	74	45	1	28	100	95	168	1.34E-11	61.2	HSPB1_HUMAN	reviewed	Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27)	HSPB1 HSP27 HSP28	Homo sapiens (Human)	205	cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028	0	0	0	PF00011;	1903	m.52311	150372	1061472	56760	1460974	15160	131588.5	1822599	21110	39365	431946	0.891381436
CHOYP_DPER_GL22446.1.1	P04792	m.52315	sp	HSPB1_HUMAN	37.838	74	45	1	28	100	95	168	1.34E-11	61.2	HSPB1_HUMAN	reviewed	Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27)	HSPB1 HSP27 HSP28	Homo sapiens (Human)	205	cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028	0	0	0	PF00011;	1904	m.52315	636340	340809.8333	7943169.909	362777.6667	568209	237382.25	5959749.143	1408708.4	1734680.25	4352681.556	1.389988397
CHOYP_DPER_GL22446.1.1	P42930	m.52312	sp	HSPB1_RAT	35.443	79	50	1	46	123	93	171	3.49E-06	47.8	HSPB1_RAT	reviewed	Heat shock protein beta-1 (HspB1) (Heat shock 27 kDa protein) (HSP 27)	Hspb1 Hsp27	Rattus norvegicus (Rat)	206	aging [GO:0007568]; cellular response to butyrate [GO:1903545]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-11 [GO:0071348]; female pregnancy [GO:0007565]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced cell death [GO:1903202]; positive regulation of neuron projection development [GO:0010976]; response to angiotensin [GO:1990776]; response to ischemia [GO:0002931]; response to muscle stretch [GO:0035994]	GO:0000502; GO:0002931; GO:0005634; GO:0005737; GO:0005819; GO:0005886; GO:0007565; GO:0007568; GO:0010976; GO:0030424; GO:0030425; GO:0031430; GO:0031674; GO:0035994; GO:0043066; GO:0043130; GO:0043204; GO:0045202; GO:0070301; GO:0071348; GO:0097512; GO:0098839; GO:1903202; GO:1903545; GO:1990776	0	0	0	PF00011;	1903	m.52311	150372	1061472	56760	1460974	15160	131588.5	1822599	21110	39365	431946	0.891381436
CHOYP_DPER_GL22446.1.1	P42930	m.52312	sp	HSPB1_RAT	35.443	79	50	1	46	123	93	171	3.49E-06	47.8	HSPB1_RAT	reviewed	Heat shock protein beta-1 (HspB1) (Heat shock 27 kDa protein) (HSP 27)	Hspb1 Hsp27	Rattus norvegicus (Rat)	206	aging [GO:0007568]; cellular response to butyrate [GO:1903545]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-11 [GO:0071348]; female pregnancy [GO:0007565]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced cell death [GO:1903202]; positive regulation of neuron projection development [GO:0010976]; response to angiotensin [GO:1990776]; response to ischemia [GO:0002931]; response to muscle stretch [GO:0035994]	GO:0000502; GO:0002931; GO:0005634; GO:0005737; GO:0005819; GO:0005886; GO:0007565; GO:0007568; GO:0010976; GO:0030424; GO:0030425; GO:0031430; GO:0031674; GO:0035994; GO:0043066; GO:0043130; GO:0043204; GO:0045202; GO:0070301; GO:0071348; GO:0097512; GO:0098839; GO:1903202; GO:1903545; GO:1990776	0	0	0	PF00011;	1904	m.52315	636340	340809.8333	7943169.909	362777.6667	568209	237382.25	5959749.143	1408708.4	1734680.25	4352681.556	1.389988397
CHOYP_DUOX1.1.4	Q8HZK2	m.14285	sp	DUOX2_PIG	38.25	1634	853	34	28	1627	34	1545	0	1068	DUOX2_PIG	reviewed	Dual oxidase 2 (EC 1.11.1.-) (EC 1.6.3.1) (NADH/NADPH thyroid oxidase p138-tox)	DUOX2	Sus scrofa (Pig)	1545	cuticle development [GO:0042335]; cytokine-mediated signaling pathway [GO:0019221]; hormone biosynthetic process [GO:0042446]; hydrogen peroxide biosynthetic process [GO:0050665]; hydrogen peroxide catabolic process [GO:0042744]; oxidation-reduction process [GO:0055114]; response to cAMP [GO:0051591]; response to oxidative stress [GO:0006979]; thyroid hormone generation [GO:0006590]	GO:0004601; GO:0005509; GO:0006590; GO:0006979; GO:0016021; GO:0016174; GO:0016324; GO:0019221; GO:0020037; GO:0030054; GO:0042335; GO:0042446; GO:0042744; GO:0050665; GO:0051591; GO:0055114	PATHWAY: Hormone biosynthesis; thyroid hormone biosynthesis.	0	0	PF03098;PF00036;PF13202;PF08022;PF01794;PF08030;	1933	m.14284	298045.5	364715.8571	1546533.667	118162.1667	246316.5	298884.5	122879.75	125764	522952.75	1490645.4	0.995086091
CHOYP_DUOX1.1.4	Q8HZK2	m.14285	sp	DUOX2_PIG	38.25	1634	853	34	28	1627	34	1545	0	1068	DUOX2_PIG	reviewed	Dual oxidase 2 (EC 1.11.1.-) (EC 1.6.3.1) (NADH/NADPH thyroid oxidase p138-tox)	DUOX2	Sus scrofa (Pig)	1545	cuticle development [GO:0042335]; cytokine-mediated signaling pathway [GO:0019221]; hormone biosynthetic process [GO:0042446]; hydrogen peroxide biosynthetic process [GO:0050665]; hydrogen peroxide catabolic process [GO:0042744]; oxidation-reduction process [GO:0055114]; response to cAMP [GO:0051591]; response to oxidative stress [GO:0006979]; thyroid hormone generation [GO:0006590]	GO:0004601; GO:0005509; GO:0006590; GO:0006979; GO:0016021; GO:0016174; GO:0016324; GO:0019221; GO:0020037; GO:0030054; GO:0042335; GO:0042446; GO:0042744; GO:0050665; GO:0051591; GO:0055114	PATHWAY: Hormone biosynthesis; thyroid hormone biosynthesis.	0	0	PF03098;PF00036;PF13202;PF08022;PF01794;PF08030;	1934	m.14285	310680	17683	24969	166763.3333	218740	979111.5	52798	23701	203451	46921	1.767623232
CHOYP_DUOX1.2.4	Q8HZK2	m.33964	sp	DUOX2_PIG	39.888	1612	853	34	6	1572	5	1545	0	1139	DUOX2_PIG	reviewed	Dual oxidase 2 (EC 1.11.1.-) (EC 1.6.3.1) (NADH/NADPH thyroid oxidase p138-tox)	DUOX2	Sus scrofa (Pig)	1545	cuticle development [GO:0042335]; cytokine-mediated signaling pathway [GO:0019221]; hormone biosynthetic process [GO:0042446]; hydrogen peroxide biosynthetic process [GO:0050665]; hydrogen peroxide catabolic process [GO:0042744]; oxidation-reduction process [GO:0055114]; response to cAMP [GO:0051591]; response to oxidative stress [GO:0006979]; thyroid hormone generation [GO:0006590]	GO:0004601; GO:0005509; GO:0006590; GO:0006979; GO:0016021; GO:0016174; GO:0016324; GO:0019221; GO:0020037; GO:0030054; GO:0042335; GO:0042446; GO:0042744; GO:0050665; GO:0051591; GO:0055114	PATHWAY: Hormone biosynthesis; thyroid hormone biosynthesis.	0	0	PF03098;PF00036;PF13202;PF08022;PF01794;PF08030;	1935	m.33964	140121.5	25799	323976.3333	126041	497758.75	503392	35481	2397699.25	556731.5	66118.33333	3.196042923
CHOYP_DUOX1.4.4	Q8HZK2	m.44612	sp	DUOX2_PIG	38.372	1634	851	34	28	1627	34	1545	0	1072	DUOX2_PIG	reviewed	Dual oxidase 2 (EC 1.11.1.-) (EC 1.6.3.1) (NADH/NADPH thyroid oxidase p138-tox)	DUOX2	Sus scrofa (Pig)	1545	cuticle development [GO:0042335]; cytokine-mediated signaling pathway [GO:0019221]; hormone biosynthetic process [GO:0042446]; hydrogen peroxide biosynthetic process [GO:0050665]; hydrogen peroxide catabolic process [GO:0042744]; oxidation-reduction process [GO:0055114]; response to cAMP [GO:0051591]; response to oxidative stress [GO:0006979]; thyroid hormone generation [GO:0006590]	GO:0004601; GO:0005509; GO:0006590; GO:0006979; GO:0016021; GO:0016174; GO:0016324; GO:0019221; GO:0020037; GO:0030054; GO:0042335; GO:0042446; GO:0042744; GO:0050665; GO:0051591; GO:0055114	PATHWAY: Hormone biosynthesis; thyroid hormone biosynthesis.	0	0	PF03098;PF00036;PF13202;PF08022;PF01794;PF08030;	1936	m.44612	310680	17683	24969	166763.3333	218740	979111.5	52798	23701	203451	46921	1.767623232
CHOYP_DUOX1.4.4	Q8HZK2	m.44612	sp	DUOX2_PIG	38.372	1634	851	34	28	1627	34	1545	0	1072	DUOX2_PIG	reviewed	Dual oxidase 2 (EC 1.11.1.-) (EC 1.6.3.1) (NADH/NADPH thyroid oxidase p138-tox)	DUOX2	Sus scrofa (Pig)	1545	cuticle development [GO:0042335]; cytokine-mediated signaling pathway [GO:0019221]; hormone biosynthetic process [GO:0042446]; hydrogen peroxide biosynthetic process [GO:0050665]; hydrogen peroxide catabolic process [GO:0042744]; oxidation-reduction process [GO:0055114]; response to cAMP [GO:0051591]; response to oxidative stress [GO:0006979]; thyroid hormone generation [GO:0006590]	GO:0004601; GO:0005509; GO:0006590; GO:0006979; GO:0016021; GO:0016174; GO:0016324; GO:0019221; GO:0020037; GO:0030054; GO:0042335; GO:0042446; GO:0042744; GO:0050665; GO:0051591; GO:0055114	PATHWAY: Hormone biosynthesis; thyroid hormone biosynthesis.	0	0	PF03098;PF00036;PF13202;PF08022;PF01794;PF08030;	1937	m.44613	54325.25	409026.6667	302146.4	103545.3333	208297.6	35503	28723.5	17213.66667	95731	3884256.182	3.769861544
CHOYP_ETFD.1.1	Q921G7	m.6881	sp	ETFD_MOUSE	74.787	587	144	3	35	619	32	616	0	936	ETFD_MOUSE	reviewed	"Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial (ETF-QO) (ETF-ubiquinone oxidoreductase) (EC 1.5.5.1) (Electron-transferring-flavoprotein dehydrogenase) (ETF dehydrogenase)"	Etfdh	Mus musculus (Mouse)	616	electron transport chain [GO:0022900]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; response to oxidative stress [GO:0006979]	GO:0004174; GO:0005739; GO:0005743; GO:0006979; GO:0009055; GO:0016020; GO:0016491; GO:0017133; GO:0022900; GO:0031305; GO:0031966; GO:0033539; GO:0043783; GO:0046872; GO:0048038; GO:0048039; GO:0051539	0	0	0	PF05187;	2113	m.6881	1514806.556	720342.7143	2784355.25	2616840.909	520876.8571	890803.6667	397596.4615	471962.2857	193417.75	552681.8889	0.307269064
CHOYP_G6PD.1.2	P05370	m.38380	sp	G6PD_RAT	68.487	476	140	5	62	530	9	481	0	692	G6PD_RAT	reviewed	Glucose-6-phosphate 1-dehydrogenase (G6PD) (EC 1.1.1.49)	G6pdx G6pd	Rattus norvegicus (Rat)	515	"cellular response to oxidative stress [GO:0034599]; cholesterol biosynthetic process [GO:0006695]; erythrocyte maturation [GO:0043249]; glucose 6-phosphate metabolic process [GO:0051156]; glucose metabolic process [GO:0006006]; glutathione metabolic process [GO:0006749]; NADPH regeneration [GO:0006740]; NADP metabolic process [GO:0006739]; negative regulation of cell growth involved in cardiac muscle cell development [GO:0061052]; negative regulation of protein glutathionylation [GO:0010734]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; pentose biosynthetic process [GO:0019322]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, oxidative branch [GO:0009051]; positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel [GO:1904879]; regulation of neuron apoptotic process [GO:0043523]; response to ethanol [GO:0045471]; response to food [GO:0032094]; response to iron(III) ion [GO:0010041]; response to organic cyclic compound [GO:0014070]; ribose phosphate biosynthetic process [GO:0046390]; substantia nigra development [GO:0021762]"	GO:0004345; GO:0005536; GO:0005634; GO:0005813; GO:0005829; GO:0006006; GO:0006098; GO:0006695; GO:0006739; GO:0006740; GO:0006749; GO:0009051; GO:0009898; GO:0010041; GO:0010734; GO:0014070; GO:0019322; GO:0021762; GO:0030246; GO:0032094; GO:0034599; GO:0043231; GO:0043249; GO:0043523; GO:0045471; GO:0046390; GO:0050661; GO:0051156; GO:0061052; GO:0070062; GO:1904879; GO:2000378	PATHWAY: Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.	0	0	PF02781;PF00479;	2201	m.38380	1144157	3013439.8	549546.5385	607411.3077	1562046.636	428645.9091	6152029.4	527677.4545	567266.2857	1130303.455	1.280563194
CHOYP_G6PD.2.2	P05370	m.46923	sp	G6PD_RAT	68.836	507	148	5	43	542	9	512	0	745	G6PD_RAT	reviewed	Glucose-6-phosphate 1-dehydrogenase (G6PD) (EC 1.1.1.49)	G6pdx G6pd	Rattus norvegicus (Rat)	515	"cellular response to oxidative stress [GO:0034599]; cholesterol biosynthetic process [GO:0006695]; erythrocyte maturation [GO:0043249]; glucose 6-phosphate metabolic process [GO:0051156]; glucose metabolic process [GO:0006006]; glutathione metabolic process [GO:0006749]; NADPH regeneration [GO:0006740]; NADP metabolic process [GO:0006739]; negative regulation of cell growth involved in cardiac muscle cell development [GO:0061052]; negative regulation of protein glutathionylation [GO:0010734]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; pentose biosynthetic process [GO:0019322]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, oxidative branch [GO:0009051]; positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel [GO:1904879]; regulation of neuron apoptotic process [GO:0043523]; response to ethanol [GO:0045471]; response to food [GO:0032094]; response to iron(III) ion [GO:0010041]; response to organic cyclic compound [GO:0014070]; ribose phosphate biosynthetic process [GO:0046390]; substantia nigra development [GO:0021762]"	GO:0004345; GO:0005536; GO:0005634; GO:0005813; GO:0005829; GO:0006006; GO:0006098; GO:0006695; GO:0006739; GO:0006740; GO:0006749; GO:0009051; GO:0009898; GO:0010041; GO:0010734; GO:0014070; GO:0019322; GO:0021762; GO:0030246; GO:0032094; GO:0034599; GO:0043231; GO:0043249; GO:0043523; GO:0045471; GO:0046390; GO:0050661; GO:0051156; GO:0061052; GO:0070062; GO:1904879; GO:2000378	PATHWAY: Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.	0	0	PF02781;PF00479;	2202	m.46923	1144157	3013439.8	549546.5385	607411.3077	1562046.636	428645.9091	6152029.4	527677.4545	567266.2857	1130303.455	1.280563194
CHOYP_GPX4-A.1.1	Q9N2J2	m.257	sp	GPX4_BOVIN	48.936	47	24	0	76	122	26	72	3.17E-10	58.2	GPX4_BOVIN	reviewed	"Phospholipid hydroperoxide glutathione peroxidase, mitochondrial (PHGPx) (EC 1.11.1.12) (Glutathione peroxidase 4) (GPx-4) (GSHPx-4)"	GPX4	Bos taurus (Bovine)	197	multicellular organism development [GO:0007275]; response to oxidative stress [GO:0006979]	GO:0004602; GO:0005739; GO:0006979; GO:0007275; GO:0047066	0	0	cd00340;	PF00255;	2274	m.257	1257869	1181418.714	722201.375	1275580.4	1345332.273	841702.7778	1320608	40145.66667	858260.5	240788.8571	0.570957526
CHOYP_GPX5.1.1	P30710	m.44157	sp	GPX5_RAT	54.237	118	47	3	1	113	97	212	1.71E-36	127	GPX5_RAT	reviewed	Epididymal secretory glutathione peroxidase (EC 1.11.1.9) (Epididymis-specific glutathione peroxidase-like protein) (EGLP) (Glutathione peroxidase 5) (GPx-5) (GSHPx-5)	Gpx5	Rattus norvegicus (Rat)	221	response to oxidative stress [GO:0006979]	GO:0004602; GO:0005576; GO:0006979	0	0	cd00340;	PF00255;	2275	m.44157	432304	537989.6667	130165	123239.5	109869.5	268769	428152	2047205	5811862.5	234411	6.591641144
CHOYP_GSH1.1.1	P19468	m.8927	sp	GSH1_RAT	61.836	621	215	11	1	615	1	605	0	785	GSH1_RAT	reviewed	Glutamate--cysteine ligase catalytic subunit (EC 6.3.2.2) (GCS heavy chain) (Gamma-ECS) (Gamma-glutamylcysteine synthetase)	Gclc Glclc	Rattus norvegicus (Rat)	637	"aging [GO:0007568]; apoptotic mitochondrial changes [GO:0008637]; cell redox homeostasis [GO:0045454]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to glucose stimulus [GO:0071333]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to insulin stimulus [GO:0032869]; cellular response to mechanical stimulus [GO:0071260]; cellular response to thyroxine stimulus [GO:0097069]; cysteine metabolic process [GO:0006534]; glutamate metabolic process [GO:0006536]; glutathione biosynthetic process [GO:0006750]; L-ascorbic acid metabolic process [GO:0019852]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of hepatic stellate cell activation [GO:2000490]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; regulation of blood vessel size [GO:0050880]; regulation of mitochondrial depolarization [GO:0051900]; response to activity [GO:0014823]; response to arsenic-containing substance [GO:0046685]; response to cadmium ion [GO:0046686]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to human chorionic gonadotropin [GO:0044752]; response to interleukin-1 [GO:0070555]; response to nitrosative stress [GO:0051409]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to xenobiotic stimulus [GO:0009410]"	GO:0000287; GO:0004357; GO:0005524; GO:0005829; GO:0006534; GO:0006536; GO:0006750; GO:0006979; GO:0007568; GO:0007584; GO:0008637; GO:0009408; GO:0009410; GO:0009725; GO:0014823; GO:0016595; GO:0017109; GO:0019852; GO:0031397; GO:0032436; GO:0032869; GO:0035729; GO:0043066; GO:0043524; GO:0043531; GO:0044344; GO:0044752; GO:0045454; GO:0045892; GO:0046685; GO:0046686; GO:0046982; GO:0050662; GO:0050880; GO:0051409; GO:0051900; GO:0070555; GO:0071260; GO:0071333; GO:0071372; GO:0097069; GO:2000490; GO:2001237	PATHWAY: Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 1/2.	0	0	PF03074;	2281	m.8927	1286438.167	275908.8333	275332.2	1057362.25	582170.8	2091339.8	445481.6	1362115	407285.875	7113066.077	3.284035466
CHOYP_HMCN1.44.44	A4IGL7	m.67044	sp	PXDN_XENTR	27.966	354	217	15	7	355	287	607	2.55E-29	124	PXDN_XENTR	reviewed	Peroxidasin (EC 1.11.1.7)	pxdn pxn	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	1457	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	GO:0004601; GO:0005576; GO:0006979; GO:0020037; GO:0042744; GO:0046872	0	0	0	PF03098;PF07679;PF13855;PF00093;	2324	m.67044	550553.4	25633	NA	616589.5	41867	860098	102608	122130.5	322093	1078181.333	1.610253998
CHOYP_HS12A.25.33	Q3SZZ2	m.60353	sp	XBP1_BOVIN	37.5	248	123	6	5	220	14	261	1.74E-35	129	XBP1_BOVIN	reviewed	"X-box-binding protein 1 (XBP-1) [Cleaved into: X-box-binding protein 1, cytoplasmic form; X-box-binding protein 1, luminal form]"	XBP1	Bos taurus (Bovine)	261	adipose tissue development [GO:0060612]; angiogenesis [GO:0001525]; cell growth [GO:0016049]; cellular response to amino acid stimulus [GO:0071230]; cellular response to fluid shear stress [GO:0071498]; cellular response to fructose stimulus [GO:0071332]; cellular response to glucose starvation [GO:0042149]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-4 [GO:0071353]; cellular response to laminar fluid shear stress [GO:0071499]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient [GO:0031670]; cellular response to oxidative stress [GO:0034599]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular triglyceride homeostasis [GO:0035356]; cholesterol homeostasis [GO:0042632]; endothelial cell proliferation [GO:0001935]; epithelial cell maturation involved in salivary gland development [GO:0060691]; exocrine pancreas development [GO:0031017]; fatty acid homeostasis [GO:0055089]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; liver development [GO:0001889]; muscle organ development [GO:0007517]; negative regulation of apoptotic process [GO:0043066]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of endoplasmic reticulum unfolded protein response [GO:1900102]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron development [GO:0048666]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of autophagy [GO:0010508]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of hepatocyte proliferation [GO:2000347]; positive regulation of histone methylation [GO:0031062]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of lactation [GO:1903489]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of plasma cell differentiation [GO:1900100]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein acetylation [GO:1901985]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of TOR signaling [GO:0032008]; positive regulation of transcription factor import into nucleus [GO:0042993]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response [GO:0006990]; protein destabilization [GO:0031648]; regulation of autophagy [GO:0010506]; response to endoplasmic reticulum stress [GO:0034976]; response to insulin-like growth factor stimulus [GO:1990418]; sterol homeostasis [GO:0055092]; transcription from RNA polymerase II promoter [GO:0006366]; ubiquitin-dependent protein catabolic process [GO:0006511]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	GO:0000122; GO:0000977; GO:0000981; GO:0001047; GO:0001158; GO:0001525; GO:0001889; GO:0001934; GO:0001935; GO:0002639; GO:0003700; GO:0005634; GO:0005737; GO:0005783; GO:0005829; GO:0006366; GO:0006511; GO:0006990; GO:0007517; GO:0010506; GO:0010508; GO:0010832; GO:0014065; GO:0016049; GO:0030176; GO:0031017; GO:0031062; GO:0031490; GO:0031648; GO:0031670; GO:0032008; GO:0032869; GO:0034599; GO:0034976; GO:0035356; GO:0035924; GO:0042149; GO:0042632; GO:0042993; GO:0043066; GO:0045348; GO:0045579; GO:0045582; GO:0045600; GO:0045944; GO:0046982; GO:0048010; GO:0048666; GO:0051024; GO:0055089; GO:0055092; GO:0060612; GO:0060691; GO:0070059; GO:0071222; GO:0071230; GO:0071332; GO:0071333; GO:0071353; GO:0071375; GO:0071498; GO:0071499; GO:1900100; GO:1900102; GO:1900103; GO:1901800; GO:1901985; GO:1902236; GO:1903489; GO:1990418; GO:2000347; GO:2000353; GO:2000778	0	0	0	PF07716;	2357	m.60352	1061063	2385709.5	2264897	94215	1001035	2731855.333	803975.6667	1957162	1148877	1970376	1.265219311
CHOYP_ISCW_ISCW008219.1.2	P08228	m.46822	sp	SODC_MOUSE	70.588	153	45	0	4	156	2	154	1.28E-74	223	SODC_MOUSE	reviewed	Superoxide dismutase [Cu-Zn] (EC 1.15.1.1)	Sod1	Mus musculus (Mouse)	154	activation of MAPK activity [GO:0000187]; aging [GO:0007568]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antibiotic [GO:0046677]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to nutrient levels [GO:0031667]; response to organic substance [GO:0010033]; response to oxidative stress [GO:0006979]; response to reactive oxygen species [GO:0000302]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	GO:0000187; GO:0000302; GO:0000303; GO:0001541; GO:0001819; GO:0001895; GO:0001975; GO:0002262; GO:0004784; GO:0005507; GO:0005615; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005758; GO:0005764; GO:0005777; GO:0005829; GO:0005886; GO:0006749; GO:0006801; GO:0006879; GO:0006979; GO:0007283; GO:0007566; GO:0007568; GO:0007569; GO:0007605; GO:0007626; GO:0008089; GO:0008090; GO:0008217; GO:0008270; GO:0009408; GO:0010033; GO:0019226; GO:0019430; GO:0030346; GO:0031012; GO:0031045; GO:0031410; GO:0031667; GO:0032287; GO:0032839; GO:0032930; GO:0034465; GO:0035865; GO:0040014; GO:0042493; GO:0042542; GO:0042554; GO:0042802; GO:0043025; GO:0043066; GO:0043085; GO:0043087; GO:0043209; GO:0043234; GO:0043524; GO:0045471; GO:0045541; GO:0045859; GO:0046677; GO:0046688; GO:0046716; GO:0048365; GO:0048678; GO:0050665; GO:0051087; GO:0051881; GO:0060047; GO:0060052; GO:0060087; GO:0060088; GO:0070062; GO:0071276; GO:0071318; GO:0072593; GO:0097332; GO:1902177; GO:1904115	0	0	cd00305;	PF00080;	2475	m.46822	3670563.4	468776.25	492295.75	89802.83333	365171.2222	320819.5	281210	369576.8571	1610264.2	335148	0.573470124
CHOYP_ISCW_ISCW008219.2.2	P08228	m.63442	sp	SODC_MOUSE	70.588	153	45	0	4	156	2	154	1.28E-74	223	SODC_MOUSE	reviewed	Superoxide dismutase [Cu-Zn] (EC 1.15.1.1)	Sod1	Mus musculus (Mouse)	154	activation of MAPK activity [GO:0000187]; aging [GO:0007568]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antibiotic [GO:0046677]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to nutrient levels [GO:0031667]; response to organic substance [GO:0010033]; response to oxidative stress [GO:0006979]; response to reactive oxygen species [GO:0000302]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	GO:0000187; GO:0000302; GO:0000303; GO:0001541; GO:0001819; GO:0001895; GO:0001975; GO:0002262; GO:0004784; GO:0005507; GO:0005615; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005758; GO:0005764; GO:0005777; GO:0005829; GO:0005886; GO:0006749; GO:0006801; GO:0006879; GO:0006979; GO:0007283; GO:0007566; GO:0007568; GO:0007569; GO:0007605; GO:0007626; GO:0008089; GO:0008090; GO:0008217; GO:0008270; GO:0009408; GO:0010033; GO:0019226; GO:0019430; GO:0030346; GO:0031012; GO:0031045; GO:0031410; GO:0031667; GO:0032287; GO:0032839; GO:0032930; GO:0034465; GO:0035865; GO:0040014; GO:0042493; GO:0042542; GO:0042554; GO:0042802; GO:0043025; GO:0043066; GO:0043085; GO:0043087; GO:0043209; GO:0043234; GO:0043524; GO:0045471; GO:0045541; GO:0045859; GO:0046677; GO:0046688; GO:0046716; GO:0048365; GO:0048678; GO:0050665; GO:0051087; GO:0051881; GO:0060047; GO:0060052; GO:0060087; GO:0060088; GO:0070062; GO:0071276; GO:0071318; GO:0072593; GO:0097332; GO:1902177; GO:1904115	0	0	cd00305;	PF00080;	2476	m.63442	3670563.4	468776.25	492295.75	89802.83333	365171.2222	320819.5	281210	369576.8571	1610264.2	335148	0.573470124
CHOYP_ISCW_ISCW010532.1.4	Q9NL98	m.11493	sp	PRDX_ASCSU	74.359	195	50	0	44	238	1	195	9.37E-109	314	PRDX_ASCSU	reviewed	Peroxiredoxin (EC 1.11.1.15) (AsPrx) (Thioredoxin peroxidase)	0	Ascaris suum (Pig roundworm) (Ascaris lumbricoides)	195	cell redox homeostasis [GO:0045454]; response to oxidative stress [GO:0006979]	GO:0004601; GO:0005737; GO:0006979; GO:0008379; GO:0016209; GO:0045454	0	0	0	PF10417;PF00578;	2486	m.11493	512133.2857	399627.7778	254216.5714	592246.3333	459379.875	69883.16667	284040.1429	196095.6	1176951.833	368687	0.945009971
CHOYP_ISCW_ISCW010532.2.4	Q9NL98	m.35454	sp	PRDX_ASCSU	73.846	195	51	0	1	195	1	195	8.32E-109	312	PRDX_ASCSU	reviewed	Peroxiredoxin (EC 1.11.1.15) (AsPrx) (Thioredoxin peroxidase)	0	Ascaris suum (Pig roundworm) (Ascaris lumbricoides)	195	cell redox homeostasis [GO:0045454]; response to oxidative stress [GO:0006979]	GO:0004601; GO:0005737; GO:0006979; GO:0008379; GO:0016209; GO:0045454	0	0	0	PF10417;PF00578;	2487	m.35454	512133.2857	399627.7778	254216.5714	592246.3333	459379.875	69883.16667	284040.1429	196095.6	1176951.833	368687	0.945009971
CHOYP_ISCW_ISCW010532.3.4	Q9NL98	m.56458	sp	PRDX_ASCSU	74.359	195	50	0	31	225	1	195	7.54E-110	316	PRDX_ASCSU	reviewed	Peroxiredoxin (EC 1.11.1.15) (AsPrx) (Thioredoxin peroxidase)	0	Ascaris suum (Pig roundworm) (Ascaris lumbricoides)	195	cell redox homeostasis [GO:0045454]; response to oxidative stress [GO:0006979]	GO:0004601; GO:0005737; GO:0006979; GO:0008379; GO:0016209; GO:0045454	0	0	0	PF10417;PF00578;	2488	m.56458	512133.2857	399627.7778	254216.5714	592246.3333	459379.875	69883.16667	284040.1429	196095.6	1176951.833	368687	0.945009971
CHOYP_ISCW_ISCW010532.4.4	Q9NL98	m.62265	sp	PRDX_ASCSU	74.359	195	50	0	1	195	1	195	2.49E-109	313	PRDX_ASCSU	reviewed	Peroxiredoxin (EC 1.11.1.15) (AsPrx) (Thioredoxin peroxidase)	0	Ascaris suum (Pig roundworm) (Ascaris lumbricoides)	195	cell redox homeostasis [GO:0045454]; response to oxidative stress [GO:0006979]	GO:0004601; GO:0005737; GO:0006979; GO:0008379; GO:0016209; GO:0045454	0	0	0	PF10417;PF00578;	2489	m.62265	512133.2857	399627.7778	254216.5714	592246.3333	459379.875	69883.16667	284040.1429	196095.6	1176951.833	368687	0.945009971
CHOYP_ISCW_ISCW012366.1.1	P53563	m.3690	sp	B2CL1_RAT	30.921	152	96	3	130	273	82	232	7.48E-17	80.9	B2CL1_RAT	reviewed	Bcl-2-like protein 1 (Bcl2-L-1) (Apoptosis regulator Bcl-X)	Bcl2l1 Bclx Blc2l	Rattus norvegicus (Rat)	233	aging [GO:0007568]; apoptotic process [GO:0006915]; cerebral cortex development [GO:0021987]; cytokinesis [GO:0000910]; endocytosis [GO:0006897]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of apoptotic process [GO:0043066]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; ovarian follicle development [GO:0001541]; regulation of apoptotic process [GO:0042981]; response to electrical stimulus [GO:0051602]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to inorganic substance [GO:0010035]; response to ischemia [GO:0002931]; response to lead ion [GO:0010288]; response to organic cyclic compound [GO:0014070]; response to organonitrogen compound [GO:0010243]; response to oxidative stress [GO:0006979]; response to peptide hormone [GO:0043434]	GO:0000910; GO:0001541; GO:0001666; GO:0002931; GO:0005739; GO:0005740; GO:0005741; GO:0005743; GO:0005759; GO:0005813; GO:0005829; GO:0006897; GO:0006915; GO:0006979; GO:0007093; GO:0007568; GO:0008630; GO:0010035; GO:0010243; GO:0010288; GO:0014070; GO:0016021; GO:0021987; GO:0030054; GO:0030672; GO:0031965; GO:0042542; GO:0042803; GO:0042981; GO:0043027; GO:0043066; GO:0043434; GO:0046982; GO:0051400; GO:0051602; GO:0097192; GO:0097371; GO:2001243	0	0	0	PF00452;PF02180;	2495	m.3691	5954836.833	449406	266357.1667	375873	197061.8334	206763.75	2988434.8	1828123.5	183205.75	485289.75	0.785778999
CHOYP_ISCW_ISCW012366.1.1	P53563	m.3692	sp	B2CL1_RAT	30.921	152	96	3	115	258	82	232	7.30E-17	80.5	B2CL1_RAT	reviewed	Bcl-2-like protein 1 (Bcl2-L-1) (Apoptosis regulator Bcl-X)	Bcl2l1 Bclx Blc2l	Rattus norvegicus (Rat)	233	aging [GO:0007568]; apoptotic process [GO:0006915]; cerebral cortex development [GO:0021987]; cytokinesis [GO:0000910]; endocytosis [GO:0006897]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of apoptotic process [GO:0043066]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; ovarian follicle development [GO:0001541]; regulation of apoptotic process [GO:0042981]; response to electrical stimulus [GO:0051602]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to inorganic substance [GO:0010035]; response to ischemia [GO:0002931]; response to lead ion [GO:0010288]; response to organic cyclic compound [GO:0014070]; response to organonitrogen compound [GO:0010243]; response to oxidative stress [GO:0006979]; response to peptide hormone [GO:0043434]	GO:0000910; GO:0001541; GO:0001666; GO:0002931; GO:0005739; GO:0005740; GO:0005741; GO:0005743; GO:0005759; GO:0005813; GO:0005829; GO:0006897; GO:0006915; GO:0006979; GO:0007093; GO:0007568; GO:0008630; GO:0010035; GO:0010243; GO:0010288; GO:0014070; GO:0016021; GO:0021987; GO:0030054; GO:0030672; GO:0031965; GO:0042542; GO:0042803; GO:0042981; GO:0043027; GO:0043066; GO:0043434; GO:0046982; GO:0051400; GO:0051602; GO:0097192; GO:0097371; GO:2001243	0	0	0	PF00452;PF02180;	2495	m.3691	5954836.833	449406	266357.1667	375873	197061.8334	206763.75	2988434.8	1828123.5	183205.75	485289.75	0.785778999
CHOYP_ISCW_ISCW020302.1.1	Q17QJ7	m.37564	sp	P5CR2_BOVIN	52.222	270	120	3	15	277	1	268	4.30E-90	275	P5CR2_BOVIN	reviewed	Pyrroline-5-carboxylate reductase 2 (P5C reductase 2) (P5CR 2) (EC 1.5.1.2)	PYCR2	Bos taurus (Bovine)	320	cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; proline biosynthetic process [GO:0006561]	GO:0004735; GO:0005739; GO:0006561; GO:0034599; GO:0055129	PATHWAY: Amino-acid biosynthesis; L-proline biosynthesis; L-proline from L-glutamate 5-semialdehyde: step 1/1.	0	0	PF03807;PF14748;	2548	m.37564	423721	660120	897143.25	6067678.857	956357	817179	447929.3333	523851.6667	158505.6667	139265	0.231729707
CHOYP_LOC100083074.1.1	Q08420	m.1592	sp	SODE_RAT	24.176	182	118	6	49	216	48	223	2.37E-09	58.9	SODE_RAT	reviewed	Extracellular superoxide dismutase [Cu-Zn] (EC-SOD) (EC 1.15.1.1) (Superoxide dismutase B)	Sod3 Sod-3	Rattus norvegicus (Rat)	244	response to copper ion [GO:0046688]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]; response to superoxide [GO:0000303]	GO:0000303; GO:0001666; GO:0004784; GO:0005507; GO:0005615; GO:0005634; GO:0005737; GO:0005802; GO:0006979; GO:0008270; GO:0031012; GO:0046688; GO:0070062	0	0	cd00305;	PF00080;	2703	m.1592	149280	127898	715463.6	218126.3333	144283	501606.1429	376881.6667	846515.83	427851.1667	385176.1667	1.873015184
CHOYP_LOC100114636.1.1	O43396	m.11052	sp	TXNL1_HUMAN	55.052	287	125	3	5	288	4	289	1.01E-113	332	TXNL1_HUMAN	reviewed	Thioredoxin-like protein 1 (32 kDa thioredoxin-related protein)	TXNL1 TRP32 TXL TXNL	Homo sapiens (Human)	289	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glycerol ether metabolic process [GO:0006662]; protein folding [GO:0006457]; sulfate assimilation [GO:0000103]	GO:0000103; GO:0000502; GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0006662; GO:0015035; GO:0015036; GO:0016671; GO:0034599; GO:0045454; GO:0070062	0	0	0	PF06201;PF00085;	2717	m.11052	504370.7143	84335	185717.4	6961696.571	399403.25	1272540.143	161912	197437.8	2654498.9	527442.625	0.59170523
CHOYP_LOC100121999.1.4	Q9Y6E0	m.23944	sp	STK24_HUMAN	71.429	350	87	5	8	350	28	371	1.30E-161	471	STK24_HUMAN	reviewed	Serine/threonine-protein kinase 24 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 3) (MST-3) (STE20-like kinase MST3) [Cleaved into: Serine/threonine-protein kinase 24 36 kDa subunit (Mammalian STE20-like protein kinase 3 N-terminal) (MST3/N); Serine/threonine-protein kinase 24 12 kDa subunit (Mammalian STE20-like protein kinase 3 C-terminal) (MST3/C)]	STK24 MST3 STK3	Homo sapiens (Human)	443	cellular component disassembly involved in execution phase of apoptosis [GO:0006921]; execution phase of apoptosis [GO:0097194]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; mitotic cell cycle [GO:0000278]; negative regulation of cell migration [GO:0030336]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of axon regeneration [GO:0048679]; response to hydrogen peroxide [GO:0042542]; signal transduction [GO:0007165]	GO:0000278; GO:0004672; GO:0004674; GO:0004702; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0005913; GO:0006468; GO:0006921; GO:0007165; GO:0008631; GO:0016020; GO:0030336; GO:0042542; GO:0046777; GO:0046872; GO:0048679; GO:0070062; GO:0097194; GO:0098641	0	0	0	PF00069;	2760	m.23944	246911.5	2041324	855477.3333	46377.5	2257489.75	1435030.5	825556.6667	121255.3333	287718	153497.75	0.518222441
CHOYP_LOC100160839.1.1	O00506	m.53063	sp	STK25_HUMAN	56.695	478	128	6	9	485	13	412	3.92E-168	484	STK25_HUMAN	reviewed	Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response kinase 1) (SOK-1) (Ste20/oxidant stress response kinase 1)	STK25 SOK1 YSK1	Homo sapiens (Human)	426	establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Golgi localization [GO:0051645]; Golgi reassembly [GO:0090168]; intrinsic apoptotic signaling pathway in response to hydrogen peroxide [GO:0036481]; positive regulation of axonogenesis [GO:0050772]; positive regulation of stress-activated MAPK cascade [GO:0032874]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; response to hydrogen peroxide [GO:0042542]; response to oxidative stress [GO:0006979]; signal transduction [GO:0007165]	GO:0000139; GO:0004672; GO:0004702; GO:0005524; GO:0005737; GO:0006468; GO:0006979; GO:0007163; GO:0007165; GO:0032874; GO:0036481; GO:0042542; GO:0042803; GO:0046777; GO:0046872; GO:0050772; GO:0051645; GO:0051683; GO:0070062; GO:0090168	0	0	0	PF00069;	2780	m.53063	246911.5	2041324	855477.3333	46377.5	2257489.75	1435030.5	825556.6667	121255.3333	287718	153497.75	0.518222441
CHOYP_LOC100211409.1.1	P04792	m.4742	sp	HSPB1_HUMAN	38.667	75	43	2	161	233	95	168	3.82E-10	60.8	HSPB1_HUMAN	reviewed	Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27)	HSPB1 HSP27 HSP28	Homo sapiens (Human)	205	cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028	0	0	0	PF00011;	2894	m.4742	651414.5556	337618.1	6317623.786	378199.4438	467184	338760.75	3826765.727	2681237.5	1244984.25	2706129.875	1.324561491
CHOYP_LOC100211409.1.1	P04792	m.4743	sp	HSPB1_HUMAN	32.099	81	54	1	46	125	89	169	1.88E-06	50.1	HSPB1_HUMAN	reviewed	Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27)	HSPB1 HSP27 HSP28	Homo sapiens (Human)	205	cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028	0	0	0	PF00011;	2894	m.4742	651414.5556	337618.1	6317623.786	378199.4438	467184	338760.75	3826765.727	2681237.5	1244984.25	2706129.875	1.324561491
CHOYP_LOC100367895.1.1	P50093	m.23456	sp	PHB2_CAEEL	24.701	251	141	10	34	263	44	267	6.21E-06	50.4	PHB2_CAEEL	reviewed	Mitochondrial prohibitin complex protein 2 (Prohibitin-2)	phb-2 T24H7.1	Caenorhabditis elegans	294	defecation [GO:0030421]; embryo development ending in birth or egg hatching [GO:0009792]; gonad development [GO:0008406]; mitochondrion morphogenesis [GO:0070584]; oogenesis [GO:0048477]; positive regulation of multicellular organism growth [GO:0040018]; regulation of oxidative phosphorylation [GO:0002082]; regulation of pharyngeal pumping [GO:0043051]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	GO:0002082; GO:0005739; GO:0006979; GO:0007283; GO:0008406; GO:0009792; GO:0016021; GO:0030421; GO:0031966; GO:0035632; GO:0040018; GO:0043051; GO:0048477; GO:0070584	0	0	cd03401;	PF01145;	3042	m.23456	112635	56659	60334	128253	17742	114799	79891	33512	59806	134150	1.123887515
CHOYP_LOC100370583.1.1	Q05655	m.56859	sp	KPCD_HUMAN	53.21	701	284	8	6	694	4	672	0	766	KPCD_HUMAN	reviewed	Protein kinase C delta type (EC 2.7.11.13) (Tyrosine-protein kinase PRKCD) (EC 2.7.10.2) (nPKC-delta) [Cleaved into: Protein kinase C delta type regulatory subunit; Protein kinase C delta type catalytic subunit (Sphingosine-dependent protein kinase-1) (SDK1)]	PRKCD	Homo sapiens (Human)	676	activation of phospholipase C activity [GO:0007202]; activation of protein kinase activity [GO:0032147]; apoptotic process [GO:0006915]; B cell proliferation [GO:0042100]; cell chemotaxis [GO:0060326]; cell cycle [GO:0007049]; cellular component disassembly involved in execution phase of apoptosis [GO:0006921]; cellular response to angiotensin [GO:1904385]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hydroperoxide [GO:0071447]; cellular senescence [GO:0090398]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; histone phosphorylation [GO:0016572]; immunoglobulin mediated immune response [GO:0016064]; interferon-gamma-mediated signaling pathway [GO:0060333]; interleukin-10 production [GO:0032613]; interleukin-12 production [GO:0032615]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of filopodium assembly [GO:0051490]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of inflammatory response [GO:0050728]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of peptidyl-tyrosine phosphorylation [GO:0050732]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of protein binding [GO:0032091]; neutrophil activation [GO:0042119]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; platelet activation [GO:0030168]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of endodeoxyribonuclease activity [GO:0032079]; positive regulation of glucosylceramide catabolic process [GO:2000753]; positive regulation of phospholipid scramblase activity [GO:1900163]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of response to DNA damage stimulus [GO:2001022]; positive regulation of sphingomyelin catabolic process [GO:2000755]; positive regulation of superoxide anion generation [GO:0032930]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of mRNA stability [GO:0043488]; regulation of receptor activity [GO:0010469]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; termination of signal transduction [GO:0023021]	GO:0002223; GO:0004672; GO:0004674; GO:0004697; GO:0004699; GO:0004715; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005783; GO:0005829; GO:0005886; GO:0005911; GO:0006468; GO:0006915; GO:0006921; GO:0007049; GO:0007165; GO:0007202; GO:0008047; GO:0008631; GO:0010469; GO:0016064; GO:0016363; GO:0016572; GO:0018105; GO:0018107; GO:0019899; GO:0019900; GO:0019901; GO:0023021; GO:0030168; GO:0030837; GO:0032079; GO:0032091; GO:0032147; GO:0032613; GO:0032615; GO:0032930; GO:0032956; GO:0034351; GO:0035307; GO:0038096; GO:0042100; GO:0042119; GO:0042307; GO:0042742; GO:0043407; GO:0043488; GO:0043560; GO:0046627; GO:0046872; GO:0048471; GO:0050728; GO:0050732; GO:0050821; GO:0051490; GO:0060326; GO:0060333; GO:0070062; GO:0070301; GO:0071447; GO:0090331; GO:0090398; GO:1900163; GO:1904385; GO:2000304; GO:2000753; GO:2000755; GO:2001022; GO:2001235	0	0	0	PF00130;PF00069;PF00433;	3164	m.56859	321777.6667	215576.6667	401597.4	194346	93448.5	234549.25	155251.6667	1368883.4	1146157.333	1458051	3.556475277
CHOYP_LOC100371808.1.2	P56597	m.15364	sp	NDK5_HUMAN	63.871	155	56	0	2	156	24	178	5.67E-76	229	NDK5_HUMAN	reviewed	Nucleoside diphosphate kinase homolog 5 (NDK-H 5) (NDP kinase homolog 5) (Inhibitor of p53-induced apoptosis-beta) (IPIA-beta) (Testis-specific nm23 homolog) (nm23-H5)	NME5	Homo sapiens (Human)	212	cilium assembly [GO:0042384]; CTP biosynthetic process [GO:0006241]; epithelial cilium movement [GO:0003351]; GTP biosynthetic process [GO:0006183]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; nucleoside metabolic process [GO:0009116]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]; UTP biosynthetic process [GO:0006228]; ventricular system development [GO:0021591]	GO:0003351; GO:0004550; GO:0005622; GO:0006183; GO:0006228; GO:0006241; GO:0007283; GO:0007286; GO:0009116; GO:0021591; GO:0036126; GO:0042384; GO:1902176	0	0	0	PF05186;PF00334;	3227	m.15364	288598.5	29334	192991	650690	71418	159705	153020	1577694	598702	3769738.143	5.075992903
CHOYP_LOC100371808.2.2	P56597	m.62772	sp	NDK5_HUMAN	65.934	182	62	0	24	205	4	185	1.39E-93	276	NDK5_HUMAN	reviewed	Nucleoside diphosphate kinase homolog 5 (NDK-H 5) (NDP kinase homolog 5) (Inhibitor of p53-induced apoptosis-beta) (IPIA-beta) (Testis-specific nm23 homolog) (nm23-H5)	NME5	Homo sapiens (Human)	212	cilium assembly [GO:0042384]; CTP biosynthetic process [GO:0006241]; epithelial cilium movement [GO:0003351]; GTP biosynthetic process [GO:0006183]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; nucleoside metabolic process [GO:0009116]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]; UTP biosynthetic process [GO:0006228]; ventricular system development [GO:0021591]	GO:0003351; GO:0004550; GO:0005622; GO:0006183; GO:0006228; GO:0006241; GO:0007283; GO:0007286; GO:0009116; GO:0021591; GO:0036126; GO:0042384; GO:1902176	0	0	0	PF05186;PF00334;	3228	m.62772	288598.5	29334	192991	650690	71418	159705	153020	1577694	598702	3769738.143	5.075992903
CHOYP_LOC100373694.1.1	P0CB97	m.11753	sp	NDUS8_PONAB	76.882	186	43	0	38	223	25	210	1.25E-103	301	NDUS8_PONAB	reviewed	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3) (Complex I-23kD) (CI-23kD) (NADH-ubiquinone oxidoreductase 23 kDa subunit)"	NDUFS8	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	210	mitochondrial respiratory chain complex I assembly [GO:0032981]; response to oxidative stress [GO:0006979]	GO:0005739; GO:0005747; GO:0006979; GO:0008137; GO:0032981; GO:0046872; GO:0051539	0	0	0	PF12838;	3367	m.11753	614771	390877	243589	131818.5	76238	NA	146470	330137	168836	342798.5	0.847668555
CHOYP_LOC100373888.9.9	P29590	m.66033	sp	PML_HUMAN	25.51	392	233	15	54	420	31	388	6.95E-18	92	PML_HUMAN	reviewed	Protein PML (Promyelocytic leukemia protein) (RING finger protein 71) (Tripartite motif-containing protein 19)	PML MYL PP8675 RNF71 TRIM19	Homo sapiens (Human)	882	"activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell cycle arrest [GO:0007050]; cell fate commitment [GO:0045165]; cellular response to interleukin-4 [GO:0071353]; cellular senescence [GO:0090398]; circadian regulation of gene expression [GO:0032922]; common-partner SMAD protein phosphorylation [GO:0007182]; defense response to virus [GO:0051607]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endoplasmic reticulum calcium ion homeostasis [GO:0032469]; entrainment of circadian clock by photoperiod [GO:0043153]; extrinsic apoptotic signaling pathway [GO:0097191]; fibroblast migration [GO:0010761]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; maintenance of protein location in nucleus [GO:0051457]; myeloid cell differentiation [GO:0030099]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell growth [GO:0030308]; negative regulation of cell proliferation [GO:0008285]; negative regulation of interleukin-1 beta secretion [GO:0050713]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:2000059]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of translation in response to oxidative stress [GO:0032938]; negative regulation of viral release from host cell [GO:1902187]; PML body organization [GO:0030578]; positive regulation of apoptotic process involved in mammary gland involution [GO:0060058]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of protein localization to chromosome, telomeric region [GO:1904816]; positive regulation of telomere maintenance [GO:0032206]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein complex assembly [GO:0006461]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; protein targeting [GO:0006605]; regulation of calcium ion transport into cytosol [GO:0010522]; regulation of cell adhesion [GO:0030155]; regulation of circadian rhythm [GO:0042752]; regulation of double-strand break repair [GO:2000779]; regulation of MHC class I biosynthetic process [GO:0045343]; regulation of protein phosphorylation [GO:0001932]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription, DNA-templated [GO:0006355]; response to cytokine [GO:0034097]; response to gamma radiation [GO:0010332]; response to hypoxia [GO:0001666]; response to UV [GO:0009411]; retinoic acid receptor signaling pathway [GO:0048384]; SMAD protein import into nucleus [GO:0007184]; transcription, DNA-templated [GO:0006351]; transforming growth factor beta receptor signaling pathway [GO:0007179]"	GO:0000784; GO:0001666; GO:0001932; GO:0002230; GO:0003677; GO:0003713; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0006351; GO:0006355; GO:0006461; GO:0006605; GO:0006915; GO:0006919; GO:0006977; GO:0007050; GO:0007179; GO:0007182; GO:0007184; GO:0008270; GO:0008285; GO:0008630; GO:0008631; GO:0009411; GO:0010332; GO:0010522; GO:0010761; GO:0016363; GO:0016525; GO:0016605; GO:0016925; GO:0030099; GO:0030155; GO:0030308; GO:0030578; GO:0031065; GO:0031625; GO:0031901; GO:0031965; GO:0032183; GO:0032206; GO:0032211; GO:0032469; GO:0032922; GO:0032938; GO:0034097; GO:0042406; GO:0042752; GO:0042771; GO:0042803; GO:0043153; GO:0043161; GO:0045087; GO:0045165; GO:0045343; GO:0045892; GO:0045930; GO:0046982; GO:0048146; GO:0048384; GO:0050713; GO:0050821; GO:0050897; GO:0051457; GO:0051607; GO:0051974; GO:0060058; GO:0060333; GO:0060444; GO:0070059; GO:0071353; GO:0090398; GO:0097191; GO:1901796; GO:1902187; GO:1904816; GO:2000059; GO:2000779; GO:2001238	0	0	0	PF12126;PF00643;	3376	m.66033	40813	36983	755180	29621	29284	39954	35112	38534	3508465	20899	4.084585275
CHOYP_LOC100377173.1.2	P04792	m.37699	sp	HSPB1_HUMAN	38.667	75	43	2	161	233	95	168	1.68E-09	59.3	HSPB1_HUMAN	reviewed	Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27)	HSPB1 HSP27 HSP28	Homo sapiens (Human)	205	cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028	0	0	0	PF00011;	3596	m.37698	2755969.8	72264.1	698586.8667	685428.0769	198614.6667	379931.6667	524564.4615	294265.0833	1047699.833	1460404.467	0.840394518
CHOYP_LOC100377173.1.2	P04792	m.37699	sp	HSPB1_HUMAN	38.667	75	43	2	161	233	95	168	1.68E-09	59.3	HSPB1_HUMAN	reviewed	Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27)	HSPB1 HSP27 HSP28	Homo sapiens (Human)	205	cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028	0	0	0	PF00011;	3597	m.37699	651414.5556	337618.1	6317623.786	378199.4438	467184	338760.75	3826765.727	2681237.5	1244984.25	2706129.875	1.324561491
CHOYP_LOC100377736.1.1	P97478	m.251	sp	COQ7_MOUSE	65.909	176	60	0	20	195	42	217	2.59E-84	251	COQ7_MOUSE	reviewed	"5-demethoxyubiquinone hydroxylase, mitochondrial (DMQ hydroxylase) (EC 1.14.13.-) (Timing protein clk-1 homolog) (Ubiquinone biosynthesis monooxygenase COQ7)"	Coq7	Mus musculus (Mouse)	217	age-dependent response to oxidative stress [GO:0001306]; cellular response to oxidative stress [GO:0034599]; determination of adult lifespan [GO:0008340]; in utero embryonic development [GO:0001701]; mitochondrial ATP synthesis coupled electron transport [GO:0042775]; mitochondrion morphogenesis [GO:0070584]; neural tube formation [GO:0001841]; neurogenesis [GO:0022008]; respiratory electron transport chain [GO:0022904]; response to oxidative stress [GO:0006979]; ubiquinone biosynthetic process [GO:0006744]	GO:0001306; GO:0001701; GO:0001841; GO:0005634; GO:0005739; GO:0006744; GO:0006979; GO:0008340; GO:0016709; GO:0022008; GO:0022904; GO:0031314; GO:0034599; GO:0042775; GO:0046872; GO:0070584	PATHWAY: Cofactor biosynthesis; ubiquinone biosynthesis. {ECO:0000255|HAMAP-Rule:MF_03194}.	0	cd01042;	PF03232;	3630	m.251	9629044.286	2157134.333	151862407	40043782.5	437049.4	9288755.75	20225328.4	17160025.17	28197127.5	4312613.8	0.387910041
CHOYP_LOC100533387.1.1	P62325	m.56132	sp	BTG1_MOUSE	47.205	161	80	2	1	156	11	171	2.18E-47	155	BTG1_MOUSE	reviewed	Protein BTG1 (B-cell translocation gene 1 protein)	Btg1	Mus musculus (Mouse)	171	negative regulation of cell proliferation [GO:0008285]; positive regulation of angiogenesis [GO:0045766]; positive regulation of catalytic activity [GO:0043085]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of fibroblast apoptotic process [GO:2000271]; positive regulation of myoblast differentiation [GO:0045663]; protein methylation [GO:0006479]; response to oxidative stress [GO:0006979]; response to peptide hormone [GO:0043434]; spermatogenesis [GO:0007283]	GO:0005634; GO:0005737; GO:0006479; GO:0006979; GO:0007283; GO:0008285; GO:0019899; GO:0043085; GO:0043434; GO:0045603; GO:0045663; GO:0045766; GO:2000271	0	0	0	PF07742;	3762	m.56131	2543439.769	822958.3333	1283052.381	844081.4815	1205274.6	1072833	262935.6	20953698.08	905398.1053	1884177.545	3.743807511
CHOYP_LOC100638372.1.1	P97478	m.60469	sp	COQ7_MOUSE	66.092	174	59	0	20	193	42	215	2.02E-83	249	COQ7_MOUSE	reviewed	"5-demethoxyubiquinone hydroxylase, mitochondrial (DMQ hydroxylase) (EC 1.14.13.-) (Timing protein clk-1 homolog) (Ubiquinone biosynthesis monooxygenase COQ7)"	Coq7	Mus musculus (Mouse)	217	age-dependent response to oxidative stress [GO:0001306]; cellular response to oxidative stress [GO:0034599]; determination of adult lifespan [GO:0008340]; in utero embryonic development [GO:0001701]; mitochondrial ATP synthesis coupled electron transport [GO:0042775]; mitochondrion morphogenesis [GO:0070584]; neural tube formation [GO:0001841]; neurogenesis [GO:0022008]; respiratory electron transport chain [GO:0022904]; response to oxidative stress [GO:0006979]; ubiquinone biosynthetic process [GO:0006744]	GO:0001306; GO:0001701; GO:0001841; GO:0005634; GO:0005739; GO:0006744; GO:0006979; GO:0008340; GO:0016709; GO:0022008; GO:0022904; GO:0031314; GO:0034599; GO:0042775; GO:0046872; GO:0070584	PATHWAY: Cofactor biosynthesis; ubiquinone biosynthesis. {ECO:0000255|HAMAP-Rule:MF_03194}.	0	cd01042;	PF03232;	3849	m.60469	183480	292165	253051233.7	345996	76015	1553638	51530	157455	1019794	1694148	0.017627819
CHOYP_LOC100698842.1.1	Q08420	m.40947	sp	SODE_RAT	29.054	148	96	7	25	171	48	187	2.92E-09	57.8	SODE_RAT	reviewed	Extracellular superoxide dismutase [Cu-Zn] (EC-SOD) (EC 1.15.1.1) (Superoxide dismutase B)	Sod3 Sod-3	Rattus norvegicus (Rat)	244	response to copper ion [GO:0046688]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]; response to superoxide [GO:0000303]	GO:0000303; GO:0001666; GO:0004784; GO:0005507; GO:0005615; GO:0005634; GO:0005737; GO:0005802; GO:0006979; GO:0008270; GO:0031012; GO:0046688; GO:0070062	0	0	cd00305;	PF00080;	3928	m.40947	186559	208482	1126469.5	365970	206897.75	35060	79125	547840.3333	44132	51690	0.361848359
CHOYP_LOC100703866.1.2	Q8K4Q6	m.44331	sp	NEIL1_MOUSE	49.231	325	152	5	1	317	1	320	1.04E-103	315	NEIL1_MOUSE	reviewed	Endonuclease 8-like 1 (EC 3.2.2.-) (EC 4.2.99.18) (DNA glycosylase/AP lyase Neil1) (DNA-(apurinic or apyrimidinic site) lyase Neil1) (Endonuclease VIII-like 1) (Nei homolog 1) (NEH1) (Nei-like protein 1)	Neil1 Nei1	Mus musculus (Mouse)	389	base-excision repair [GO:0006284]; DNA repair [GO:0006281]; negative regulation of nuclease activity [GO:0032074]; nucleotide-excision repair [GO:0006289]; response to oxidative stress [GO:0006979]	GO:0003684; GO:0003906; GO:0005634; GO:0005694; GO:0005737; GO:0005815; GO:0006281; GO:0006284; GO:0006289; GO:0006979; GO:0008022; GO:0008270; GO:0016798; GO:0016829; GO:0019104; GO:0032074	0	0	0	PF01149;PF06831;PF09292;	3940	m.44330	612738.6667	90328311	159442182	146111.25	46292413.67	10210595.6	30487981.25	25471100.25	1754813.5	7664090.5	0.25465984
CHOYP_LOC100711559.1.1	Q6NW52	m.10313	sp	MSRB2_DANRE	70.079	127	38	0	64	190	50	176	4.42E-65	201	MSRB2_DANRE	reviewed	"Methionine-R-sulfoxide reductase B2, mitochondrial (MsrB2) (EC 1.8.4.-)"	msrb2 zgc:85965	Danio rerio (Zebrafish) (Brachydanio rerio)	180	actin filament polymerization [GO:0030041]; protein repair [GO:0030091]; response to oxidative stress [GO:0006979]	GO:0003779; GO:0005739; GO:0006979; GO:0030041; GO:0030091; GO:0033743; GO:0046872	0	0	0	PF01641;	3978	m.10313	38624	72782.5	406638	517682	7876774.333	1047783	277814.5	1184173	320791.5	239474.5	0.344464091
CHOYP_LOC100744089.1.1	Q7ZVK3	m.58530	sp	SIR2_DANRE	53.134	367	145	8	10	368	20	367	1.88E-124	366	SIR2_DANRE	reviewed	NAD-dependent protein deacetylase sirtuin-2 (EC 3.5.1.-) (Regulatory protein SIR2 homolog 2) (SIR2-like protein 2)	sirt2 zgc:77003	Danio rerio (Zebrafish) (Brachydanio rerio)	379	cellular response to caloric restriction [GO:0061433]; cellular response to hypoxia [GO:0071456]; cellular response to oxidative stress [GO:0034599]; cilium morphogenesis [GO:0060271]; histone H4 deacetylation [GO:0070933]; negative regulation of autophagy [GO:0010507]; negative regulation of cell proliferation [GO:0008285]; negative regulation of oligodendrocyte progenitor proliferation [GO:0070446]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061428]; positive regulation of DNA binding [GO:0043388]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia [GO:2000777]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein deacetylation [GO:0006476]; regulation of cell cycle [GO:0051726]; tubulin deacetylation [GO:0090042]	GO:0000122; GO:0004407; GO:0005634; GO:0005694; GO:0005720; GO:0005737; GO:0005813; GO:0005814; GO:0005819; GO:0005829; GO:0006476; GO:0008270; GO:0008285; GO:0010507; GO:0030496; GO:0032436; GO:0033010; GO:0033270; GO:0034599; GO:0034979; GO:0042177; GO:0042903; GO:0043204; GO:0043209; GO:0043220; GO:0043388; GO:0044224; GO:0045944; GO:0046970; GO:0048471; GO:0051726; GO:0060271; GO:0061428; GO:0061433; GO:0070403; GO:0070446; GO:0070933; GO:0071456; GO:0072686; GO:0072687; GO:0090042; GO:0097386; GO:1900119; GO:2000378; GO:2000777	0	0	0	PF02146;	4005	m.58530	326315	40446	97110	197819.5	50139	341792	61122	169866	1138766.5	213182.6667	2.703918799
CHOYP_LOC100893535.1.1	O43396	m.27958	sp	TXNL1_HUMAN	55.052	287	125	3	27	310	4	289	3.10E-113	332	TXNL1_HUMAN	reviewed	Thioredoxin-like protein 1 (32 kDa thioredoxin-related protein)	TXNL1 TRP32 TXL TXNL	Homo sapiens (Human)	289	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glycerol ether metabolic process [GO:0006662]; protein folding [GO:0006457]; sulfate assimilation [GO:0000103]	GO:0000103; GO:0000502; GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0006662; GO:0015035; GO:0015036; GO:0016671; GO:0034599; GO:0045454; GO:0070062	0	0	0	PF06201;PF00085;	4148	m.27958	504370.7143	84335	185717.4	6961696.571	399403.25	1272540.143	161912	197437.8	2654498.9	527442.625	0.59170523
CHOYP_LOC101070737.1.3	Q9CQZ5	m.1746	sp	NDUA6_MOUSE	53.608	97	45	0	21	117	21	117	2.65E-31	110	NDUA6_MOUSE	reviewed	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (Complex I-B14) (CI-B14) (NADH-ubiquinone oxidoreductase B14 subunit)	Ndufa6	Mus musculus (Mouse)	131	oxidation-reduction process [GO:0055114]; response to oxidative stress [GO:0006979]	GO:0005739; GO:0005747; GO:0006979; GO:0031966; GO:0055114	0	0	0	PF05347;	4243	m.1746	268325	579955.5	660821.5	150287	254186	243418	429551	110335	NA	248476	0.673987171
CHOYP_LOC101070737.2.3	Q9CQZ5	m.11531	sp	NDUA6_MOUSE	56.757	111	48	0	33	143	21	131	5.80E-42	138	NDUA6_MOUSE	reviewed	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (Complex I-B14) (CI-B14) (NADH-ubiquinone oxidoreductase B14 subunit)	Ndufa6	Mus musculus (Mouse)	131	oxidation-reduction process [GO:0055114]; response to oxidative stress [GO:0006979]	GO:0005739; GO:0005747; GO:0006979; GO:0031966; GO:0055114	0	0	0	PF05347;	4244	m.11531	268325	579955.5	660821.5	150287	254186	243418	429551	110335	NA	248476	0.673987171
CHOYP_LOC101070737.3.3	Q9CQZ5	m.20342	sp	NDUA6_MOUSE	56.25	112	49	0	19	130	20	131	6.48E-42	138	NDUA6_MOUSE	reviewed	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (Complex I-B14) (CI-B14) (NADH-ubiquinone oxidoreductase B14 subunit)	Ndufa6	Mus musculus (Mouse)	131	oxidation-reduction process [GO:0055114]; response to oxidative stress [GO:0006979]	GO:0005739; GO:0005747; GO:0006979; GO:0031966; GO:0055114	0	0	0	PF05347;	4245	m.20342	268325	579955.5	660821.5	150287	254186	243418	429551	110335	NA	248476	0.673987171
CHOYP_LOC101169658.1.3	Q08420	m.18820	sp	SODE_RAT	29.268	164	96	7	318	467	65	222	1.04E-08	59.3	SODE_RAT	reviewed	Extracellular superoxide dismutase [Cu-Zn] (EC-SOD) (EC 1.15.1.1) (Superoxide dismutase B)	Sod3 Sod-3	Rattus norvegicus (Rat)	244	response to copper ion [GO:0046688]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]; response to superoxide [GO:0000303]	GO:0000303; GO:0001666; GO:0004784; GO:0005507; GO:0005615; GO:0005634; GO:0005737; GO:0005802; GO:0006979; GO:0008270; GO:0031012; GO:0046688; GO:0070062	0	0	cd00305;	PF00080;	4295	m.18820	3199548.667	31548	NA	34315	558122	644544.5	NA	219611	102210	345421	0.343082241
CHOYP_LOC101169658.2.3	Q08420	m.20752	sp	SODE_RAT	25.654	191	112	8	147	323	48	222	4.94E-09	59.3	SODE_RAT	reviewed	Extracellular superoxide dismutase [Cu-Zn] (EC-SOD) (EC 1.15.1.1) (Superoxide dismutase B)	Sod3 Sod-3	Rattus norvegicus (Rat)	244	response to copper ion [GO:0046688]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]; response to superoxide [GO:0000303]	GO:0000303; GO:0001666; GO:0004784; GO:0005507; GO:0005615; GO:0005634; GO:0005737; GO:0005802; GO:0006979; GO:0008270; GO:0031012; GO:0046688; GO:0070062	0	0	cd00305;	PF00080;	4296	m.20752	149280	127898	715463.6	218126.3333	144283	501606.1429	376881.6667	846515.83	427851.1667	385176.1667	1.873015184
CHOYP_LOC586494.1.1	Q96T60	m.50214	sp	PNKP_HUMAN	43.75	352	195	3	85	434	153	503	5.64E-95	299	PNKP_HUMAN	reviewed	Bifunctional polynucleotide phosphatase/kinase (DNA 5'-kinase/3'-phosphatase) (Polynucleotide kinase-3'-phosphatase) [Includes: Polynucleotide 3'-phosphatase (EC 3.1.3.32) (2'(3')-polynucleotidase); Polynucleotide 5'-hydroxyl-kinase (EC 2.7.1.78)]	PNKP	Homo sapiens (Human)	521	"dephosphorylation [GO:0016311]; DNA 3' dephosphorylation involved in DNA repair [GO:0098504]; DNA damage response, detection of DNA damage [GO:0042769]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; nucleotide-excision repair, DNA damage removal [GO:0000718]; nucleotide phosphorylation [GO:0046939]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]"	GO:0000718; GO:0003684; GO:0003690; GO:0004519; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0006261; GO:0006281; GO:0006979; GO:0009314; GO:0016020; GO:0016311; GO:0017076; GO:0019201; GO:0032212; GO:0042769; GO:0046403; GO:0046404; GO:0046939; GO:0051973; GO:0098504; GO:1904355	0	0	0	PF08645;	4508	m.50214	38352	196480	17034	197169	231756.5	19112	182532	317064.5	4283751.667	309445	7.508767614
CHOYP_LOC589012.1.1	P16056	m.26892	sp	MET_MOUSE	27.807	748	441	24	42	731	635	1341	4.59E-74	266	MET_MOUSE	reviewed	Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)	Met	Mus musculus (Mouse)	1379	activation of MAPK activity [GO:0000187]; adult behavior [GO:0030534]; brain development [GO:0007420]; branching morphogenesis of an epithelial tube [GO:0048754]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; chemical synaptic transmission [GO:0007268]; endothelial cell morphogenesis [GO:0001886]; excitatory postsynaptic potential [GO:0060079]; glucose homeostasis [GO:0042593]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; liver development [GO:0001889]; modulation of synaptic transmission [GO:0050804]; muscle cell migration [GO:0014812]; muscle organ development [GO:0007517]; myoblast proliferation [GO:0051450]; myotube differentiation [GO:0014902]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-mediated programmed cell death [GO:1901299]; negative regulation of transforming growth factor beta production [GO:0071635]; placenta development [GO:0001890]; positive chemotaxis [GO:0050918]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of glucose transport [GO:0010828]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein autophosphorylation [GO:0046777]; reactive oxygen species metabolic process [GO:0072593]; regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling [GO:0060665]; regulation of cellular response to oxidative stress [GO:1900407]; regulation of interleukin-6 production [GO:0032675]; semaphorin-plexin signaling pathway [GO:0071526]; skeletal muscle tissue development [GO:0007519]	GO:0000187; GO:0001886; GO:0001889; GO:0001890; GO:0004672; GO:0005008; GO:0005524; GO:0007268; GO:0007420; GO:0007517; GO:0007519; GO:0009925; GO:0009986; GO:0010629; GO:0010828; GO:0014812; GO:0014902; GO:0016020; GO:0016021; GO:0019903; GO:0030534; GO:0032675; GO:0042593; GO:0045944; GO:0046777; GO:0048012; GO:0048754; GO:0050804; GO:0050918; GO:0051450; GO:0055013; GO:0060048; GO:0060079; GO:0060665; GO:0071526; GO:0071635; GO:0072593; GO:0098794; GO:1900407; GO:1900745; GO:1901299; GO:2001028	0	0	0	PF07714;PF01437;PF01403;PF01833;	4533	m.26892	59396	278817.25	441964.5	100422.4	75555	87041.5	1927668	49157	98312.25	69018.25	2.333509368
CHOYP_LOC593522.1.2	Q8VIJ6	m.5381	sp	SFPQ_MOUSE	53.986	276	127	0	137	412	283	558	1.82E-98	317	SFPQ_MOUSE	reviewed	"Splicing factor, proline- and glutamine-rich (DNA-binding p52/p100 complex, 100 kDa subunit) (Polypyrimidine tract-binding protein-associated-splicing factor) (PSF) (PTB-associated-splicing factor)"	Sfpq Psf	Mus musculus (Mouse)	699	"alternative mRNA splicing, via spliceosome [GO:0000380]; cellular response to DNA damage stimulus [GO:0006974]; chromosome organization [GO:0051276]; double-strand break repair via homologous recombination [GO:0000724]; histone H3 deacetylation [GO:0070932]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of sister chromatid cohesion [GO:0045876]; regulation of cell cycle [GO:0051726]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]"	GO:0000122; GO:0000166; GO:0000380; GO:0000724; GO:0000785; GO:0000976; GO:0000980; GO:0001047; GO:0003682; GO:0005634; GO:0005654; GO:0005737; GO:0006351; GO:0006974; GO:0016363; GO:0042382; GO:0042752; GO:0042754; GO:0042826; GO:0044212; GO:0044822; GO:0045876; GO:0045892; GO:0048511; GO:0051276; GO:0051726; GO:0070932; GO:0090575; GO:1902177	0	0	0	PF08075;PF00076;	4576	m.5381	702141.75	5968319.625	3565680.667	693003.8571	240771.2222	572577.5	13249886.14	2090472.3	32003783.67	1434927.167	4.418264365
CHOYP_LOC593522.2.2	Q8VIJ6	m.33859	sp	SFPQ_MOUSE	53.986	276	127	0	61	336	283	558	2.27E-99	313	SFPQ_MOUSE	reviewed	"Splicing factor, proline- and glutamine-rich (DNA-binding p52/p100 complex, 100 kDa subunit) (Polypyrimidine tract-binding protein-associated-splicing factor) (PSF) (PTB-associated-splicing factor)"	Sfpq Psf	Mus musculus (Mouse)	699	"alternative mRNA splicing, via spliceosome [GO:0000380]; cellular response to DNA damage stimulus [GO:0006974]; chromosome organization [GO:0051276]; double-strand break repair via homologous recombination [GO:0000724]; histone H3 deacetylation [GO:0070932]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of sister chromatid cohesion [GO:0045876]; regulation of cell cycle [GO:0051726]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]"	GO:0000122; GO:0000166; GO:0000380; GO:0000724; GO:0000785; GO:0000976; GO:0000980; GO:0001047; GO:0003682; GO:0005634; GO:0005654; GO:0005737; GO:0006351; GO:0006974; GO:0016363; GO:0042382; GO:0042752; GO:0042754; GO:0042826; GO:0044212; GO:0044822; GO:0045876; GO:0045892; GO:0048511; GO:0051276; GO:0051726; GO:0070932; GO:0090575; GO:1902177	0	0	0	PF08075;PF00076;	4577	m.33859	702141.75	5968319.625	3565680.667	693003.8571	240771.2222	572577.5	13249886.14	2090472.3	32003783.67	1434927.167	4.418264365
CHOYP_LOC732900.1.1	Q641Y2	m.62814	sp	NDUS2_RAT	74.596	433	106	2	50	480	33	463	0	694	NDUS2_RAT	reviewed	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3) (Complex I-49kD) (CI-49kD) (NADH-ubiquinone oxidoreductase 49 kDa subunit)"	Ndufs2	Rattus norvegicus (Rat)	463	response to oxidative stress [GO:0006979]	GO:0005654; GO:0005747; GO:0006979; GO:0008137; GO:0046872; GO:0048038; GO:0051287; GO:0051539	0	0	0	PF00346;	4690	m.62814	611978.2857	71807	151885.8571	607586.3636	364593.375	211992.1111	327024.4286	268393.7	928690.7778	680148.3571	1.336531348
CHOYP_LONM.1.1	Q8CGK3	m.7031	sp	LONM_MOUSE	56.443	939	362	11	80	1010	41	940	0	1064	LONM_MOUSE	reviewed	"Lon protease homolog, mitochondrial (EC 3.4.21.-) (Lon protease-like protein) (LONP) (Mitochondrial ATP-dependent protease Lon) (Serine protease 15)"	Lonp1 Prss15	Mus musculus (Mouse)	949	aging [GO:0007568]; cellular response to oxidative stress [GO:0034599]; chaperone-mediated protein complex assembly [GO:0051131]; misfolded or incompletely synthesized protein catabolic process [GO:0006515]; mitochondrion organization [GO:0007005]; oxidation-dependent protein catabolic process [GO:0070407]; protein homooligomerization [GO:0051260]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of mitochondrial DNA replication [GO:0090296]; response to aluminum ion [GO:0010044]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]	GO:0001666; GO:0003697; GO:0003727; GO:0004176; GO:0004252; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005759; GO:0006508; GO:0006515; GO:0007005; GO:0007568; GO:0009725; GO:0010044; GO:0016020; GO:0016887; GO:0034599; GO:0042645; GO:0043531; GO:0043565; GO:0051131; GO:0051260; GO:0051603; GO:0051880; GO:0070182; GO:0070361; GO:0070407; GO:0090296	0	0	0	PF00004;PF05362;PF02190;	4738	m.7031	341798.3636	228530.4545	1670853.929	462345.0769	8692922.643	279741.8333	6474960.125	382523.8182	175739.3529	332510.4737	0.670864637
CHOYP_MRP1.10.10	Q8CG09	m.64931	sp	MRP1_RAT	46.497	1570	782	19	4	1554	2	1532	0	1395	MRP1_RAT	reviewed	Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter)	Abcc1 Mrp1	Rattus norvegicus (Rat)	1532	cell chemotaxis [GO:0060326]; daunorubicin transport [GO:0043215]; drug export [GO:0046618]; drug transmembrane transport [GO:0006855]; glutathione transmembrane transport [GO:0034775]; negative regulation of neuron death [GO:1901215]; phospholipid efflux [GO:0033700]; plasma membrane long-chain fatty acid transport [GO:0015911]; positive regulation of cell migration [GO:0030335]; response to drug [GO:0042493]; response to oxidative stress [GO:0006979]; transmembrane transport [GO:0055085]; xenobiotic transport [GO:0042908]	GO:0005324; GO:0005524; GO:0005737; GO:0005886; GO:0005887; GO:0006855; GO:0006979; GO:0008559; GO:0015238; GO:0015431; GO:0015562; GO:0015911; GO:0016020; GO:0016323; GO:0016491; GO:0030335; GO:0033700; GO:0034040; GO:0034634; GO:0034775; GO:0042493; GO:0042908; GO:0043215; GO:0046618; GO:0046624; GO:0055085; GO:0060326; GO:1901215	0	0	0	PF00664;PF00005;	4871	m.64931	70780.33333	34651.66667	293493.5	50868.66667	44886.33333	142494	333917.6667	33090	172906.5	57362.4	1.495451239
CHOYP_MRP1.5.10	Q8CG09	m.34368	sp	MRP1_RAT	48.925	1582	738	20	4	1566	2	1532	0	1486	MRP1_RAT	reviewed	Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter)	Abcc1 Mrp1	Rattus norvegicus (Rat)	1532	cell chemotaxis [GO:0060326]; daunorubicin transport [GO:0043215]; drug export [GO:0046618]; drug transmembrane transport [GO:0006855]; glutathione transmembrane transport [GO:0034775]; negative regulation of neuron death [GO:1901215]; phospholipid efflux [GO:0033700]; plasma membrane long-chain fatty acid transport [GO:0015911]; positive regulation of cell migration [GO:0030335]; response to drug [GO:0042493]; response to oxidative stress [GO:0006979]; transmembrane transport [GO:0055085]; xenobiotic transport [GO:0042908]	GO:0005324; GO:0005524; GO:0005737; GO:0005886; GO:0005887; GO:0006855; GO:0006979; GO:0008559; GO:0015238; GO:0015431; GO:0015562; GO:0015911; GO:0016020; GO:0016323; GO:0016491; GO:0030335; GO:0033700; GO:0034040; GO:0034634; GO:0034775; GO:0042493; GO:0042908; GO:0043215; GO:0046618; GO:0046624; GO:0055085; GO:0060326; GO:1901215	0	0	0	PF00664;PF00005;	4872	m.34368	123865.75	90858.33333	1467877.75	264262.5	39696	122759.6667	1297777.75	85224.75	631839	199719.25	1.176566539
CHOYP_NEMVEDRAFT_V1G198897.2.6	Q3SZZ2	m.4751	sp	XBP1_BOVIN	49.593	123	55	2	5	120	14	136	3.34E-28	106	XBP1_BOVIN	reviewed	"X-box-binding protein 1 (XBP-1) [Cleaved into: X-box-binding protein 1, cytoplasmic form; X-box-binding protein 1, luminal form]"	XBP1	Bos taurus (Bovine)	261	adipose tissue development [GO:0060612]; angiogenesis [GO:0001525]; cell growth [GO:0016049]; cellular response to amino acid stimulus [GO:0071230]; cellular response to fluid shear stress [GO:0071498]; cellular response to fructose stimulus [GO:0071332]; cellular response to glucose starvation [GO:0042149]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-4 [GO:0071353]; cellular response to laminar fluid shear stress [GO:0071499]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient [GO:0031670]; cellular response to oxidative stress [GO:0034599]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular triglyceride homeostasis [GO:0035356]; cholesterol homeostasis [GO:0042632]; endothelial cell proliferation [GO:0001935]; epithelial cell maturation involved in salivary gland development [GO:0060691]; exocrine pancreas development [GO:0031017]; fatty acid homeostasis [GO:0055089]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; liver development [GO:0001889]; muscle organ development [GO:0007517]; negative regulation of apoptotic process [GO:0043066]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of endoplasmic reticulum unfolded protein response [GO:1900102]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron development [GO:0048666]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of autophagy [GO:0010508]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of hepatocyte proliferation [GO:2000347]; positive regulation of histone methylation [GO:0031062]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of lactation [GO:1903489]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of plasma cell differentiation [GO:1900100]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein acetylation [GO:1901985]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of TOR signaling [GO:0032008]; positive regulation of transcription factor import into nucleus [GO:0042993]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response [GO:0006990]; protein destabilization [GO:0031648]; regulation of autophagy [GO:0010506]; response to endoplasmic reticulum stress [GO:0034976]; response to insulin-like growth factor stimulus [GO:1990418]; sterol homeostasis [GO:0055092]; transcription from RNA polymerase II promoter [GO:0006366]; ubiquitin-dependent protein catabolic process [GO:0006511]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	GO:0000122; GO:0000977; GO:0000981; GO:0001047; GO:0001158; GO:0001525; GO:0001889; GO:0001934; GO:0001935; GO:0002639; GO:0003700; GO:0005634; GO:0005737; GO:0005783; GO:0005829; GO:0006366; GO:0006511; GO:0006990; GO:0007517; GO:0010506; GO:0010508; GO:0010832; GO:0014065; GO:0016049; GO:0030176; GO:0031017; GO:0031062; GO:0031490; GO:0031648; GO:0031670; GO:0032008; GO:0032869; GO:0034599; GO:0034976; GO:0035356; GO:0035924; GO:0042149; GO:0042632; GO:0042993; GO:0043066; GO:0045348; GO:0045579; GO:0045582; GO:0045600; GO:0045944; GO:0046982; GO:0048010; GO:0048666; GO:0051024; GO:0055089; GO:0055092; GO:0060612; GO:0060691; GO:0070059; GO:0071222; GO:0071230; GO:0071332; GO:0071333; GO:0071353; GO:0071375; GO:0071498; GO:0071499; GO:1900100; GO:1900102; GO:1900103; GO:1901800; GO:1901985; GO:1902236; GO:1903489; GO:1990418; GO:2000347; GO:2000353; GO:2000778	0	0	0	PF07716;	5041	m.4748	404447.4118	399862.6154	511241.3333	355512.5333	1024721.933	213654.2857	1321401.389	711064.7857	15319009.27	398925.3182	6.663754542
CHOYP_PDIA1.1.1	P04785	m.5297	sp	PDIA1_RAT	61.475	488	178	3	18	495	22	509	0	617	PDIA1_RAT	reviewed	Protein disulfide-isomerase (PDI) (EC 5.3.4.1) (Cellular thyroid hormone-binding protein) (Prolyl 4-hydroxylase subunit beta)	P4hb Pdia1	Rattus norvegicus (Rat)	509	cell redox homeostasis [GO:0045454]; cellular response to hypoxia [GO:0071456]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; positive regulation of viral entry into host cell [GO:0046598]; protein folding [GO:0006457]; regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902175]; response to endoplasmic reticulum stress [GO:0034976]	GO:0003756; GO:0004656; GO:0005783; GO:0005788; GO:0005793; GO:0005925; GO:0006457; GO:0009897; GO:0016222; GO:0018401; GO:0019899; GO:0034663; GO:0034976; GO:0042470; GO:0044822; GO:0045454; GO:0046598; GO:0046982; GO:0070062; GO:0071456; GO:1902175	0	0	0	PF00085;	5236	m.5297	1418696.52	1427371.708	2906920.391	2269920.917	1160875	1183863.421	1490713.5	864647.2778	3997461.32	2991380.348	1.14637553
CHOYP_PHUM_PHUM071280.1.1	Q9Y6E0	m.25507	sp	STK24_HUMAN	69.146	363	92	5	8	363	28	377	1.98E-162	472	STK24_HUMAN	reviewed	Serine/threonine-protein kinase 24 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 3) (MST-3) (STE20-like kinase MST3) [Cleaved into: Serine/threonine-protein kinase 24 36 kDa subunit (Mammalian STE20-like protein kinase 3 N-terminal) (MST3/N); Serine/threonine-protein kinase 24 12 kDa subunit (Mammalian STE20-like protein kinase 3 C-terminal) (MST3/C)]	STK24 MST3 STK3	Homo sapiens (Human)	443	cellular component disassembly involved in execution phase of apoptosis [GO:0006921]; execution phase of apoptosis [GO:0097194]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; mitotic cell cycle [GO:0000278]; negative regulation of cell migration [GO:0030336]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of axon regeneration [GO:0048679]; response to hydrogen peroxide [GO:0042542]; signal transduction [GO:0007165]	GO:0000278; GO:0004672; GO:0004674; GO:0004702; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0005913; GO:0006468; GO:0006921; GO:0007165; GO:0008631; GO:0016020; GO:0030336; GO:0042542; GO:0046777; GO:0046872; GO:0048679; GO:0070062; GO:0097194; GO:0098641	0	0	0	PF00069;	5275	m.25507	246911.5	2041324	855477.3333	46377.5	2257489.75	1435030.5	825556.6667	121255.3333	287718	153497.75	0.518222441
CHOYP_PHUM_PHUM596890.1.1	Q63073	m.10990	sp	BTG1_RAT	46.584	161	81	2	1	156	11	171	4.52E-47	154	BTG1_RAT	reviewed	Protein BTG1 (Anti-proliferative factor) (B-cell translocation gene 1 protein)	Btg1	Rattus norvegicus (Rat)	171	negative regulation of cell proliferation [GO:0008285]; positive regulation of angiogenesis [GO:0045766]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of fibroblast apoptotic process [GO:2000271]; protein methylation [GO:0006479]; response to oxidative stress [GO:0006979]; response to peptide hormone [GO:0043434]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]	GO:0005634; GO:0005737; GO:0006479; GO:0006979; GO:0007283; GO:0007286; GO:0008285; GO:0019899; GO:0043434; GO:0045603; GO:0045766; GO:2000271	0	0	0	PF07742;	5329	m.10989	1082034.333	675344.4706	1160378.294	1124097.611	887140.6154	719613.9375	970006.2174	1012582.526	5398580.053	1675689.5	1.983461454
CHOYP_PLSP.2.5	H2A0M7	m.40533	sp	PLSP_PINMG	42.75	669	314	17	2	629	60	700	3.24E-140	430	PLSP_PINMG	reviewed	Peroxidase-like protein	0	Pinctada margaritifera (Black-lipped pearl oyster)	793	response to oxidative stress [GO:0006979]	GO:0004601; GO:0005576; GO:0006979; GO:0020037	0	0	0	PF03098;	5358	m.40533	52347	94873	44280	494780	356927.5	308450	32671	NA	47791	2240733	3.150913169
CHOYP_PLSP.4.5	H2A0M7	m.44386	sp	PLSP_PINMG	42.751	676	319	16	73	708	60	707	3.32E-138	431	PLSP_PINMG	reviewed	Peroxidase-like protein	0	Pinctada margaritifera (Black-lipped pearl oyster)	793	response to oxidative stress [GO:0006979]	GO:0004601; GO:0005576; GO:0006979; GO:0020037	0	0	0	PF03098;	5359	m.44386	52347	94873	44280	494780	356927.5	308450	32671	NA	47791	2240733	3.150913169
CHOYP_PNCB.1.1	Q9VQX4	m.57201	sp	PNCB_DROME	67.103	535	176	0	36	570	21	555	0	748	PNCB_DROME	reviewed	Nicotinate phosphoribosyltransferase (NAPRTase) (EC 6.3.4.21)	CG3714	Drosophila melanogaster (Fruit fly)	555	NAD biosynthetic process [GO:0009435]; nicotinate nucleotide salvage [GO:0019358]; response to oxidative stress [GO:0006979]	GO:0004514; GO:0004516; GO:0005829; GO:0006979; GO:0009435; GO:0016874; GO:0019358	PATHWAY: Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1.	0	0	PF04095;	5372	m.57201	39938.5	1267824.667	157329.5	1180542	182526	468122	147241	NA	186544.5	1303218	0.930430476
CHOYP_RNP1B.1.1	P04792	m.59889	sp	HSPB1_HUMAN	36.145	83	52	1	46	127	89	171	9.52E-09	54.7	HSPB1_HUMAN	reviewed	Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27)	HSPB1 HSP27 HSP28	Homo sapiens (Human)	205	cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028	0	0	0	PF00011;	5723	m.59889	1996542	25739	171339.5	665833.5	17751	388418.5	80537.5	6428505	591267.3333	768276.25	2.869800582
CHOYP_RNP1B.1.1	P04792	m.59889	sp	HSPB1_HUMAN	36.145	83	52	1	46	127	89	171	9.52E-09	54.7	HSPB1_HUMAN	reviewed	Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27)	HSPB1 HSP27 HSP28	Homo sapiens (Human)	205	cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028	0	0	0	PF00011;	5724	m.59893	636340	340809.8333	7943169.909	362777.6667	568209	237382.25	5959749.143	1408708.4	1734680.25	4352681.556	1.389988397
CHOYP_RNP1B.1.1	P04792	m.59893	sp	HSPB1_HUMAN	37.838	74	45	1	28	100	95	168	1.34E-11	61.2	HSPB1_HUMAN	reviewed	Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27)	HSPB1 HSP27 HSP28	Homo sapiens (Human)	205	cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028	0	0	0	PF00011;	5723	m.59889	1996542	25739	171339.5	665833.5	17751	388418.5	80537.5	6428505	591267.3333	768276.25	2.869800582
CHOYP_RNP1B.1.1	P04792	m.59893	sp	HSPB1_HUMAN	37.838	74	45	1	28	100	95	168	1.34E-11	61.2	HSPB1_HUMAN	reviewed	Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27)	HSPB1 HSP27 HSP28	Homo sapiens (Human)	205	cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028	0	0	0	PF00011;	5724	m.59893	636340	340809.8333	7943169.909	362777.6667	568209	237382.25	5959749.143	1408708.4	1734680.25	4352681.556	1.389988397
CHOYP_RS21.1.4	O14463	m.13400	sp	TRX1_SCHPO	53.922	102	47	0	1	102	1	102	6.30E-35	118	TRX1_SCHPO	reviewed	Thioredoxin-1 (TR-1) (Trx-1)	trx1 trx2 SPAC7D4.07c	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	103	"cell redox homeostasis [GO:0045454]; cellular response to reactive oxygen species [GO:0034614]; glycerol ether metabolic process [GO:0006662]; hydrogen peroxide catabolic process [GO:0042744]; L-methionine biosynthetic process from methionine sulphoxide [GO:1990355]; positive regulation of cellular response to oxidative stress [GO:1900409]; protein folding [GO:0006457]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]"	GO:0005634; GO:0005737; GO:0005829; GO:0006457; GO:0006662; GO:0015035; GO:0016209; GO:0016671; GO:0019379; GO:0034614; GO:0042744; GO:0045454; GO:1900409; GO:1990355	0	0	0	PF00085;	5827	m.13400	131849.3333	734266	236332	378741.3333	1644346	1438813	434611.5	122780	344496.6667	24489965.45	8.584344593
CHOYP_RS6.3.12	Q99MQ3	m.5754	sp	PINK1_MOUSE	35.749	414	221	8	117	521	128	505	3.53E-75	254	PINK1_MOUSE	reviewed	"Serine/threonine-protein kinase PINK1, mitochondrial (EC 2.7.11.1) (BRPK) (PTEN-induced putative kinase protein 1)"	Pink1	Mus musculus (Mouse)	580	"cellular response to hypoxia [GO:0071456]; cellular response to oxidative stress [GO:0034599]; cellular response to toxic substance [GO:0097237]; establishment of protein localization to mitochondrion [GO:0072655]; intracellular signal transduction [GO:0035556]; maintenance of protein location in mitochondrion [GO:0072656]; mitochondrion organization [GO:0007005]; mitophagy [GO:0000422]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of autophagosome assembly [GO:1902902]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway [GO:1903384]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide [GO:1903751]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mitochondrial fission [GO:0090258]; negative regulation of mitophagy [GO:1903147]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced cell death [GO:1903202]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; peptidyl-serine autophosphorylation [GO:0036289]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of catecholamine secretion [GO:0033605]; positive regulation of cristae formation [GO:1903852]; positive regulation of dopamine secretion [GO:0033603]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of mitochondrial electron transport, NADH to ubiquinone [GO:1902958]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of synaptic transmission, dopaminergic [GO:0032226]; positive regulation of translation [GO:0045727]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of hydrogen peroxide metabolic process [GO:0010310]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mitochondrion organization [GO:0010821]; regulation of neuron apoptotic process [GO:0043523]; regulation of oxidative phosphorylation [GO:0002082]; regulation of protein complex assembly [GO:0043254]; regulation of protein targeting to mitochondrion [GO:1903214]; regulation of protein ubiquitination [GO:0031396]; regulation of reactive oxygen species metabolic process [GO:2000377]; respiratory electron transport chain [GO:0022904]; response to oxidative stress [GO:0006979]; response to stress [GO:0006950]"	GO:0000287; GO:0000422; GO:0000785; GO:0001934; GO:0002020; GO:0002082; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005739; GO:0005741; GO:0005742; GO:0005743; GO:0005758; GO:0005829; GO:0005856; GO:0006468; GO:0006950; GO:0006979; GO:0007005; GO:0010310; GO:0010629; GO:0010821; GO:0010857; GO:0016020; GO:0016239; GO:0016242; GO:0016301; GO:0016567; GO:0018105; GO:0022904; GO:0030424; GO:0031307; GO:0031396; GO:0031625; GO:0031932; GO:0032226; GO:0033138; GO:0033603; GO:0033605; GO:0034599; GO:0035307; GO:0035556; GO:0036289; GO:0043123; GO:0043254; GO:0043422; GO:0043523; GO:0043524; GO:0044297; GO:0045727; GO:0048471; GO:0050821; GO:0051091; GO:0051881; GO:0055131; GO:0071456; GO:0072655; GO:0072656; GO:0090141; GO:0090200; GO:0090258; GO:0097237; GO:0097449; GO:0098779; GO:1901727; GO:1902902; GO:1902958; GO:1903147; GO:1903202; GO:1903214; GO:1903298; GO:1903384; GO:1903751; GO:1903852; GO:1903955; GO:2000377; GO:2000378	0	0	0	PF00069;	5899	m.5755	222333.6667	10068763.57	65457.95	106437.8571	18187961	7527201.75	516518.6	11119337.4	411293.75	56527.77381	0.685173668
CHOYP_RSMB.2.2	P04792	m.37626	sp	HSPB1_HUMAN	38.667	75	43	2	161	233	95	168	3.82E-10	60.8	HSPB1_HUMAN	reviewed	Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27)	HSPB1 HSP27 HSP28	Homo sapiens (Human)	205	cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028	0	0	0	PF00011;	5940	m.37626	651414.5556	337618.1	6317623.786	378199.4438	467184	338760.75	3826765.727	2681237.5	1244984.25	2706129.875	1.324561491
CHOYP_RTJK.3.3	O14463	m.35968	sp	TRX1_SCHPO	53.922	102	47	0	1	102	1	102	6.30E-35	118	TRX1_SCHPO	reviewed	Thioredoxin-1 (TR-1) (Trx-1)	trx1 trx2 SPAC7D4.07c	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	103	"cell redox homeostasis [GO:0045454]; cellular response to reactive oxygen species [GO:0034614]; glycerol ether metabolic process [GO:0006662]; hydrogen peroxide catabolic process [GO:0042744]; L-methionine biosynthetic process from methionine sulphoxide [GO:1990355]; positive regulation of cellular response to oxidative stress [GO:1900409]; protein folding [GO:0006457]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]"	GO:0005634; GO:0005737; GO:0005829; GO:0006457; GO:0006662; GO:0015035; GO:0016209; GO:0016671; GO:0019379; GO:0034614; GO:0042744; GO:0045454; GO:1900409; GO:1990355	0	0	0	PF00085;	5953	m.35968	131849.3333	734266	236332	378741.3333	1644346	1438813	434611.5	122780	344496.6667	24489965.45	8.584344593
CHOYP_SFPQ.1.1	Q8VIJ6	m.15746	sp	SFPQ_MOUSE	53.986	276	127	0	137	412	283	558	2.63E-99	317	SFPQ_MOUSE	reviewed	"Splicing factor, proline- and glutamine-rich (DNA-binding p52/p100 complex, 100 kDa subunit) (Polypyrimidine tract-binding protein-associated-splicing factor) (PSF) (PTB-associated-splicing factor)"	Sfpq Psf	Mus musculus (Mouse)	699	"alternative mRNA splicing, via spliceosome [GO:0000380]; cellular response to DNA damage stimulus [GO:0006974]; chromosome organization [GO:0051276]; double-strand break repair via homologous recombination [GO:0000724]; histone H3 deacetylation [GO:0070932]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of sister chromatid cohesion [GO:0045876]; regulation of cell cycle [GO:0051726]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]"	GO:0000122; GO:0000166; GO:0000380; GO:0000724; GO:0000785; GO:0000976; GO:0000980; GO:0001047; GO:0003682; GO:0005634; GO:0005654; GO:0005737; GO:0006351; GO:0006974; GO:0016363; GO:0042382; GO:0042752; GO:0042754; GO:0042826; GO:0044212; GO:0044822; GO:0045876; GO:0045892; GO:0048511; GO:0051276; GO:0051726; GO:0070932; GO:0090575; GO:1902177	0	0	0	PF08075;PF00076;	6045	m.15746	702141.75	5968319.625	3565680.667	693003.8571	240771.2222	572577.5	13249886.14	2090472.3	32003783.67	1434927.167	4.418264365
CHOYP_SMP_049250.1.1	P42930	m.1835	sp	HSPB1_RAT	32.71	107	70	2	15	119	67	173	5.31E-08	55.1	HSPB1_RAT	reviewed	Heat shock protein beta-1 (HspB1) (Heat shock 27 kDa protein) (HSP 27)	Hspb1 Hsp27	Rattus norvegicus (Rat)	206	aging [GO:0007568]; cellular response to butyrate [GO:1903545]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-11 [GO:0071348]; female pregnancy [GO:0007565]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced cell death [GO:1903202]; positive regulation of neuron projection development [GO:0010976]; response to angiotensin [GO:1990776]; response to ischemia [GO:0002931]; response to muscle stretch [GO:0035994]	GO:0000502; GO:0002931; GO:0005634; GO:0005737; GO:0005819; GO:0005886; GO:0007565; GO:0007568; GO:0010976; GO:0030424; GO:0030425; GO:0031430; GO:0031674; GO:0035994; GO:0043066; GO:0043130; GO:0043204; GO:0045202; GO:0070301; GO:0071348; GO:0097512; GO:0098839; GO:1903202; GO:1903545; GO:1990776	0	0	0	PF00011;	6101	m.1835	150372	1061472	56760	1460974	15160	131588.5	1822599	21110	39365	431946	0.891381436
CHOYP_SODM.1.2	P04179	m.45531	sp	SODM_HUMAN	63.182	220	79	2	6	224	2	220	3.23E-102	298	SODM_HUMAN	reviewed	"Superoxide dismutase [Mn], mitochondrial (EC 1.15.1.1)"	SOD2	Homo sapiens (Human)	222	age-dependent response to reactive oxygen species [GO:0001315]; negative regulation of cell proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; oxygen homeostasis [GO:0032364]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to reactive oxygen species [GO:0000302]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]; vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure [GO:0003069]	GO:0000302; GO:0000303; GO:0001315; GO:0001836; GO:0003069; GO:0004784; GO:0005739; GO:0005759; GO:0006357; GO:0006801; GO:0008217; GO:0008285; GO:0019430; GO:0030145; GO:0032364; GO:0042802; GO:0043524; GO:0051289; GO:0070062; GO:1902176	0	0	0	PF02777;PF00081;	6155	m.45530	78490.66667	205071	1617600.75	761757.5	19247.5	55224.5	179952	489340.6667	436601.75	183744	0.501409013
CHOYP_TXND3.1.4	Q95YJ5	m.3505	sp	TXND3_CIOIN	51.832	573	235	7	2	550	65	620	0	561	TXND3_CIOIN	reviewed	Thioredoxin domain-containing protein 3 homolog (Dynein intermediate chain 3)	CiIC3	Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis)	653	cell differentiation [GO:0030154]; cell redox homeostasis [GO:0045454]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; multicellular organism development [GO:0007275]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; spermatogenesis [GO:0007283]; UTP biosynthetic process [GO:0006228]	GO:0004550; GO:0005622; GO:0006183; GO:0006228; GO:0006241; GO:0007275; GO:0007283; GO:0030154; GO:0045454; GO:1902176	0	0	0	PF00334;PF00085;	6535	m.3505	152669.6	106456.2222	314763.4444	236118.0833	127394.6923	468009.0714	901755.8	359669	5085400.679	459100.9	7.759675276
CHOYP_UBP37.1.1	Q08420	m.15559	sp	SODE_RAT	27.333	150	102	6	21	169	48	191	1.88E-10	61.6	SODE_RAT	reviewed	Extracellular superoxide dismutase [Cu-Zn] (EC-SOD) (EC 1.15.1.1) (Superoxide dismutase B)	Sod3 Sod-3	Rattus norvegicus (Rat)	244	response to copper ion [GO:0046688]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]; response to superoxide [GO:0000303]	GO:0000303; GO:0001666; GO:0004784; GO:0005507; GO:0005615; GO:0005634; GO:0005737; GO:0005802; GO:0006979; GO:0008270; GO:0031012; GO:0046688; GO:0070062	0	0	cd00305;	PF00080;	6572	m.15559	149280	145904.5	715463.6	294631.5	178660.6667	579099.6667	494118	846515.83	402935	452613.6	1.870211463
CHOYP_UBQL4.1.1	Q8R317	m.37426	sp	UBQL1_MOUSE	51.171	598	216	12	7	573	25	577	0	527	UBQL1_MOUSE	reviewed	Ubiquilin-1 (Protein linking IAP with cytoskeleton 1) (PLIC-1)	Ubqln1 Plic1	Mus musculus (Mouse)	582	aggrephagy [GO:0035973]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; cellular response to hypoxia [GO:0071456]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; macroautophagy [GO:0016236]; negative regulation of autophagosome maturation [GO:1901097]; negative regulation of store-operated calcium channel activity [GO:1901340]; negative regulation of toll-like receptor 3 signaling pathway [GO:0034140]; positive regulation of ER-associated ubiquitin-dependent protein catabolic process [GO:1903071]; positive regulation of protein ubiquitination [GO:0031398]; regulation of autophagosome assembly [GO:2000785]; regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902175]; regulation of protein ubiquitination [GO:0031396]; response to endoplasmic reticulum stress [GO:0034976]	GO:0000045; GO:0000502; GO:0005102; GO:0005654; GO:0005737; GO:0005776; GO:0005783; GO:0005886; GO:0016235; GO:0016236; GO:0019215; GO:0019900; GO:0030433; GO:0031396; GO:0031398; GO:0031410; GO:0031593; GO:0034140; GO:0034976; GO:0035973; GO:0042802; GO:0043234; GO:0048471; GO:0071456; GO:0097352; GO:1901097; GO:1901340; GO:1902175; GO:1903071; GO:2000785	0	0	0	PF00627;PF00240;	6575	m.37426	149614.875	613898.1429	1367740.857	689446.6667	1169927.333	1397881.714	272775.3333	5041098.571	350485.6667	77469.625	1.789119691
CHOYP_contig_050645	Q08420	m.60289	sp	SODE_RAT	26.667	150	103	6	31	179	48	191	1.87E-09	58.9	SODE_RAT	reviewed	Extracellular superoxide dismutase [Cu-Zn] (EC-SOD) (EC 1.15.1.1) (Superoxide dismutase B)	Sod3 Sod-3	Rattus norvegicus (Rat)	244	response to copper ion [GO:0046688]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]; response to superoxide [GO:0000303]	GO:0000303; GO:0001666; GO:0004784; GO:0005507; GO:0005615; GO:0005634; GO:0005737; GO:0005802; GO:0006979; GO:0008270; GO:0031012; GO:0046688; GO:0070062	0	0	cd00305;	PF00080;	1664	m.60289	149280	145904.5	715463.6	294631.5	178660.6667	579099.6667	494118	846515.83	402935	452613.6	1.870211463