CHOYP_4EBP1.1.1 Q13541 m.12045 sp 4EBP1_HUMAN 56.881 109 42 4 42 147 12 118 9.41E-34 117 4EBP1_HUMAN reviewed Eukaryotic translation initiation factor 4E-binding protein 1 (4E-BP1) (eIF4E-binding protein 1) (Phosphorylated heat- and acid-stable protein regulated by insulin 1) (PHAS-I) EIF4EBP1 Homo sapiens (Human) 118 cellular response to hypoxia [GO:0071456]; G1/S transition of mitotic cell cycle [GO:0000082]; insulin receptor signaling pathway [GO:0008286]; IRES-dependent translational initiation [GO:0002192]; lung development [GO:0030324]; negative regulation of protein complex assembly [GO:0031333]; negative regulation of translational initiation [GO:0045947]; positive regulation of mitotic cell cycle [GO:0045931]; response to ethanol [GO:0045471]; response to ischemia [GO:0002931]; TOR signaling [GO:0031929] GO:0000082; GO:0002192; GO:0002931; GO:0005654; GO:0005737; GO:0005829; GO:0008190; GO:0008286; GO:0030324; GO:0030371; GO:0031333; GO:0031929; GO:0043234; GO:0045471; GO:0045931; GO:0045947; GO:0071456 0 0 0 PF05456; 16 m.12045 604063.2 644443.4286 2124 1652333.273 1527421.333 1735288.1 992177.5 1408983.167 5571512.8 3639799.182 3.012776552 CHOYP_BAG1.1.2 Q99933 m.846 sp BAG1_HUMAN 36.923 195 118 3 1 194 139 329 2.01E-32 122 BAG1_HUMAN reviewed BAG family molecular chaperone regulator 1 (BAG-1) (Bcl-2-associated athanogene 1) BAG1 HAP Homo sapiens (Human) 345 apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0070389]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034] GO:0000774; GO:0005057; GO:0005634; GO:0005737; GO:0005829; GO:0006915; GO:0007166; GO:0043066; GO:0070389; GO:1900034 0 0 0 PF02179;PF00240; 331 m.846 1066671 1436990.5 46641 2873231.25 648607 549186.75 910454 1409270.5 4610789.5 1159230 1.422715827 CHOYP_BAG1.2.2 Q99933 m.60616 sp BAG1_HUMAN 37.427 171 106 1 43 213 170 339 7.68E-30 116 BAG1_HUMAN reviewed BAG family molecular chaperone regulator 1 (BAG-1) (Bcl-2-associated athanogene 1) BAG1 HAP Homo sapiens (Human) 345 apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0070389]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034] GO:0000774; GO:0005057; GO:0005634; GO:0005737; GO:0005829; GO:0006915; GO:0007166; GO:0043066; GO:0070389; GO:1900034 0 0 0 PF02179;PF00240; 332 m.60616 1066671 1436990.5 46641 2873231.25 648607 549186.75 910454 1409270.5 4610789.5 1159230 1.422715827 CHOYP_BAG3.1.1 O95429 m.15160 sp BAG4_HUMAN 38.776 98 56 1 344 437 360 457 3.30E-15 81.3 BAG4_HUMAN reviewed BAG family molecular chaperone regulator 4 (BAG-4) (Bcl-2-associated athanogene 4) (Silencer of death domains) BAG4 SODD Homo sapiens (Human) 457 "cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to tumor necrosis factor [GO:0071356]; negative regulation of apoptotic process [GO:0043066]; negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity [GO:2001145]; negative regulation of protein targeting to mitochondrion [GO:1903215]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell adhesion [GO:0045785]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of stress fiber assembly [GO:0051496]; protein folding [GO:0006457]; protein localization to plasma membrane [GO:0072659]; regulation of cellular response to heat [GO:1900034]; ruffle assembly [GO:0097178]; tumor necrosis factor-mediated signaling pathway [GO:0033209]" GO:0000774; GO:0005057; GO:0005634; GO:0005829; GO:0005886; GO:0006457; GO:0010763; GO:0030838; GO:0031625; GO:0033138; GO:0033209; GO:0043066; GO:0044822; GO:0045785; GO:0051496; GO:0051897; GO:0071356; GO:0071364; GO:0072659; GO:0097178; GO:1900034; GO:1903215; GO:2001145 0 0 0 PF02179; 333 m.15160 522634 66919.5 60152 1074832.5 44503 2129184 527999 60445 170897 44323 1.657874521 CHOYP_BRAFLDRAFT_113552.1.1 Q1W374 m.29171 sp PMM_WHEAT 57.085 247 104 1 17 263 1 245 2.56E-107 313 PMM_WHEAT reviewed Phosphomannomutase (EC 5.4.2.8) (TaPMM) 0 Triticum aestivum (Wheat) 249 GDP-mannose biosynthetic process [GO:0009298] GO:0004615; GO:0005737; GO:0009298 PATHWAY: Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; alpha-D-mannose 1-phosphate from D-fructose 6-phosphate: step 2/2. 0 0 PF03332; 389 m.29171 1772650.25 85632.66667 319026.6667 609792.5 539888.3333 101511.6667 184016.3333 936088 3036607.667 388349.75 1.396629637 CHOYP_BRAFLDRAFT_113596.1.1 A4IGP0 m.53557 sp HIKES_XENTR 56.345 197 83 3 1 195 1 196 5.59E-79 237 HIKES_XENTR reviewed Protein Hikeshi 0 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) 197 cellular response to heat [GO:0034605]; protein import into nucleus [GO:0006606]; protein transport [GO:0015031] GO:0005622; GO:0005634; GO:0005829; GO:0006606; GO:0008565; GO:0015031; GO:0030544; GO:0034605 0 0 0 PF05603; 390 m.53557 88459 273432 69648 22989 41091 571497 27582 28415 178057 1015153 3.673596049 CHOYP_BRAFLDRAFT_114843.1.2 P63018 m.14727 sp HSP7C_RAT 83.966 237 34 1 1 237 87 319 7.96E-141 411 HSP7C_RAT reviewed Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8) Hspa8 Hsc70 Hsc73 Rattus norvegicus (Rat) 646 "aging [GO:0007568]; axo-dendritic transport [GO:0008088]; cellular protein complex disassembly [GO:0043624]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; cerebellum development [GO:0021549]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein folding [GO:0061077]; chaperone mediated protein folding requiring cofactor [GO:0051085]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; clathrin coat disassembly [GO:0072318]; estrous cycle [GO:0044849]; forebrain development [GO:0030900]; G1/S transition of mitotic cell cycle [GO:0000082]; intracellular protein transmembrane import [GO:0044743]; kidney development [GO:0001822]; mRNA processing [GO:0006397]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of catalytic activity [GO:0043085]; positive regulation of gene expression [GO:0010628]; positive regulation of lysosomal membrane permeability [GO:0097214]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein refolding [GO:1904592]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein autophosphorylation [GO:0046777]; protein import into nucleus [GO:0006606]; protein refolding [GO:0042026]; regulation of protein complex stability [GO:0061635]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to nickel cation [GO:0010045]; response to odorant [GO:1990834]; response to progesterone [GO:0032570]; response to starvation [GO:0042594]; RNA splicing [GO:0008380]; sensory perception of smell [GO:0007608]; skeletal muscle tissue development [GO:0007519]; slow axonal transport [GO:1990832]; transcription, DNA-templated [GO:0006351]" GO:0000082; GO:0000974; GO:0001822; GO:0001916; GO:0001917; GO:0003723; GO:0005102; GO:0005524; GO:0005634; GO:0005681; GO:0005730; GO:0005737; GO:0005764; GO:0005765; GO:0005776; GO:0005829; GO:0005874; GO:0005882; GO:0005886; GO:0006351; GO:0006397; GO:0006606; GO:0007519; GO:0007568; GO:0007608; GO:0008021; GO:0008088; GO:0008134; GO:0008380; GO:0009408; GO:0009986; GO:0010045; GO:0010628; GO:0010667; GO:0014069; GO:0014823; GO:0016887; GO:0019899; GO:0021549; GO:0030424; GO:0030425; GO:0030529; GO:0030900; GO:0031686; GO:0032279; GO:0032355; GO:0032570; GO:0034605; GO:0042026; GO:0042277; GO:0042470; GO:0042493; GO:0042594; GO:0042623; GO:0043005; GO:0043025; GO:0043085; GO:0043195; GO:0043197; GO:0043198; GO:0043204; GO:0043234; GO:0043531; GO:0043624; GO:0044743; GO:0044849; GO:0045121; GO:0045471; GO:0045862; GO:0045892; GO:0046777; GO:0048471; GO:0050766; GO:0051082; GO:0051085; GO:0061077; GO:0061635; GO:0061684; GO:0061741; GO:0070062; GO:0071276; GO:0072318; GO:0097214; GO:1903206; GO:1904592; GO:1904593; GO:1904764; GO:1990124; GO:1990832; GO:1990833; GO:1990834; GO:1990836 0 0 0 PF00012; 408 m.14727 120382 14295 734687.5 173373 NA 47768 NA 432836 40636 193387 0.685337393 CHOYP_BRAFLDRAFT_114843.1.2 P63018 m.14727 sp HSP7C_RAT 83.966 237 34 1 1 237 87 319 7.96E-141 411 HSP7C_RAT reviewed Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8) Hspa8 Hsc70 Hsc73 Rattus norvegicus (Rat) 646 "aging [GO:0007568]; axo-dendritic transport [GO:0008088]; cellular protein complex disassembly [GO:0043624]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; cerebellum development [GO:0021549]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein folding [GO:0061077]; chaperone mediated protein folding requiring cofactor [GO:0051085]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; clathrin coat disassembly [GO:0072318]; estrous cycle [GO:0044849]; forebrain development [GO:0030900]; G1/S transition of mitotic cell cycle [GO:0000082]; intracellular protein transmembrane import [GO:0044743]; kidney development [GO:0001822]; mRNA processing [GO:0006397]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of catalytic activity [GO:0043085]; positive regulation of gene expression [GO:0010628]; positive regulation of lysosomal membrane permeability [GO:0097214]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein refolding [GO:1904592]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein autophosphorylation [GO:0046777]; protein import into nucleus [GO:0006606]; protein refolding [GO:0042026]; regulation of protein complex stability [GO:0061635]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to nickel cation [GO:0010045]; response to odorant [GO:1990834]; response to progesterone [GO:0032570]; response to starvation [GO:0042594]; RNA splicing [GO:0008380]; sensory perception of smell [GO:0007608]; skeletal muscle tissue development [GO:0007519]; slow axonal transport [GO:1990832]; transcription, DNA-templated [GO:0006351]" GO:0000082; GO:0000974; GO:0001822; GO:0001916; GO:0001917; GO:0003723; GO:0005102; GO:0005524; GO:0005634; GO:0005681; GO:0005730; GO:0005737; GO:0005764; GO:0005765; GO:0005776; GO:0005829; GO:0005874; GO:0005882; GO:0005886; GO:0006351; GO:0006397; GO:0006606; GO:0007519; GO:0007568; GO:0007608; GO:0008021; GO:0008088; GO:0008134; GO:0008380; GO:0009408; GO:0009986; GO:0010045; GO:0010628; GO:0010667; GO:0014069; GO:0014823; GO:0016887; GO:0019899; GO:0021549; GO:0030424; GO:0030425; GO:0030529; GO:0030900; GO:0031686; GO:0032279; GO:0032355; GO:0032570; GO:0034605; GO:0042026; GO:0042277; GO:0042470; GO:0042493; GO:0042594; GO:0042623; GO:0043005; GO:0043025; GO:0043085; GO:0043195; GO:0043197; GO:0043198; GO:0043204; GO:0043234; GO:0043531; GO:0043624; GO:0044743; GO:0044849; GO:0045121; GO:0045471; GO:0045862; GO:0045892; GO:0046777; GO:0048471; GO:0050766; GO:0051082; GO:0051085; GO:0061077; GO:0061635; GO:0061684; GO:0061741; GO:0070062; GO:0071276; GO:0072318; GO:0097214; GO:1903206; GO:1904592; GO:1904593; GO:1904764; GO:1990124; GO:1990832; GO:1990833; GO:1990834; GO:1990836 0 0 0 PF00012; 409 m.14729 120382 14295 734687.5 173373 NA 47768 NA 432836 40636 193387 0.685337393 CHOYP_BRAFLDRAFT_114843.1.2 P63018 m.14728 sp HSP7C_RAT 88.652 141 16 0 1 141 314 454 1.31E-79 251 HSP7C_RAT reviewed Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8) Hspa8 Hsc70 Hsc73 Rattus norvegicus (Rat) 646 "aging [GO:0007568]; axo-dendritic transport [GO:0008088]; cellular protein complex disassembly [GO:0043624]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; cerebellum development [GO:0021549]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein folding [GO:0061077]; chaperone mediated protein folding requiring cofactor [GO:0051085]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; clathrin coat disassembly [GO:0072318]; estrous cycle [GO:0044849]; forebrain development [GO:0030900]; G1/S transition of mitotic cell cycle [GO:0000082]; intracellular protein transmembrane import [GO:0044743]; kidney development [GO:0001822]; mRNA processing [GO:0006397]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of catalytic activity [GO:0043085]; positive regulation of gene expression [GO:0010628]; positive regulation of lysosomal membrane permeability [GO:0097214]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein refolding [GO:1904592]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein autophosphorylation [GO:0046777]; protein import into nucleus [GO:0006606]; protein refolding [GO:0042026]; regulation of protein complex stability [GO:0061635]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to nickel cation [GO:0010045]; response to odorant [GO:1990834]; response to progesterone [GO:0032570]; response to starvation [GO:0042594]; RNA splicing [GO:0008380]; sensory perception of smell [GO:0007608]; skeletal muscle tissue development [GO:0007519]; slow axonal transport [GO:1990832]; transcription, DNA-templated [GO:0006351]" GO:0000082; GO:0000974; GO:0001822; GO:0001916; GO:0001917; GO:0003723; GO:0005102; GO:0005524; GO:0005634; GO:0005681; GO:0005730; GO:0005737; GO:0005764; GO:0005765; GO:0005776; GO:0005829; GO:0005874; GO:0005882; GO:0005886; GO:0006351; GO:0006397; GO:0006606; GO:0007519; GO:0007568; GO:0007608; GO:0008021; GO:0008088; GO:0008134; GO:0008380; GO:0009408; GO:0009986; GO:0010045; GO:0010628; GO:0010667; GO:0014069; GO:0014823; GO:0016887; GO:0019899; GO:0021549; GO:0030424; GO:0030425; GO:0030529; GO:0030900; GO:0031686; GO:0032279; GO:0032355; GO:0032570; GO:0034605; GO:0042026; GO:0042277; GO:0042470; GO:0042493; GO:0042594; GO:0042623; GO:0043005; GO:0043025; GO:0043085; GO:0043195; GO:0043197; GO:0043198; GO:0043204; GO:0043234; GO:0043531; GO:0043624; GO:0044743; GO:0044849; GO:0045121; GO:0045471; GO:0045862; GO:0045892; GO:0046777; GO:0048471; GO:0050766; GO:0051082; GO:0051085; GO:0061077; GO:0061635; GO:0061684; GO:0061741; GO:0070062; GO:0071276; GO:0072318; GO:0097214; GO:1903206; GO:1904592; GO:1904593; GO:1904764; GO:1990124; GO:1990832; GO:1990833; GO:1990834; GO:1990836 0 0 0 PF00012; 408 m.14727 120382 14295 734687.5 173373 NA 47768 NA 432836 40636 193387 0.685337393 CHOYP_BRAFLDRAFT_114843.1.2 P63018 m.14728 sp HSP7C_RAT 88.652 141 16 0 1 141 314 454 1.31E-79 251 HSP7C_RAT reviewed Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8) Hspa8 Hsc70 Hsc73 Rattus norvegicus (Rat) 646 "aging [GO:0007568]; axo-dendritic transport [GO:0008088]; cellular protein complex disassembly [GO:0043624]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; cerebellum development [GO:0021549]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein folding [GO:0061077]; chaperone mediated protein folding requiring cofactor [GO:0051085]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; clathrin coat disassembly [GO:0072318]; estrous cycle [GO:0044849]; forebrain development [GO:0030900]; G1/S transition of mitotic cell cycle [GO:0000082]; intracellular protein transmembrane import [GO:0044743]; kidney development [GO:0001822]; mRNA processing [GO:0006397]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of catalytic activity [GO:0043085]; positive regulation of gene expression [GO:0010628]; positive regulation of lysosomal membrane permeability [GO:0097214]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein refolding [GO:1904592]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein autophosphorylation [GO:0046777]; protein import into nucleus [GO:0006606]; protein refolding [GO:0042026]; regulation of protein complex stability [GO:0061635]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to nickel cation [GO:0010045]; response to odorant [GO:1990834]; response to progesterone [GO:0032570]; response to starvation [GO:0042594]; RNA splicing [GO:0008380]; sensory perception of smell [GO:0007608]; skeletal muscle tissue development [GO:0007519]; slow axonal transport [GO:1990832]; transcription, DNA-templated [GO:0006351]" GO:0000082; GO:0000974; GO:0001822; GO:0001916; GO:0001917; GO:0003723; GO:0005102; GO:0005524; GO:0005634; GO:0005681; GO:0005730; GO:0005737; GO:0005764; GO:0005765; GO:0005776; GO:0005829; GO:0005874; GO:0005882; GO:0005886; GO:0006351; GO:0006397; GO:0006606; GO:0007519; GO:0007568; GO:0007608; GO:0008021; GO:0008088; GO:0008134; GO:0008380; GO:0009408; GO:0009986; GO:0010045; GO:0010628; GO:0010667; GO:0014069; GO:0014823; GO:0016887; GO:0019899; GO:0021549; GO:0030424; GO:0030425; GO:0030529; GO:0030900; GO:0031686; GO:0032279; GO:0032355; GO:0032570; GO:0034605; GO:0042026; GO:0042277; GO:0042470; GO:0042493; GO:0042594; GO:0042623; GO:0043005; GO:0043025; GO:0043085; GO:0043195; GO:0043197; GO:0043198; GO:0043204; GO:0043234; GO:0043531; GO:0043624; GO:0044743; GO:0044849; GO:0045121; GO:0045471; GO:0045862; GO:0045892; GO:0046777; GO:0048471; GO:0050766; GO:0051082; GO:0051085; GO:0061077; GO:0061635; GO:0061684; GO:0061741; GO:0070062; GO:0071276; GO:0072318; GO:0097214; GO:1903206; GO:1904592; GO:1904593; GO:1904764; GO:1990124; GO:1990832; GO:1990833; GO:1990834; GO:1990836 0 0 0 PF00012; 409 m.14729 120382 14295 734687.5 173373 NA 47768 NA 432836 40636 193387 0.685337393 CHOYP_BRAFLDRAFT_118658.1.2 Q13442 m.49602 sp HAP28_HUMAN 64.557 79 27 1 424 502 72 149 9.39E-22 95.9 HAP28_HUMAN reviewed 28 kDa heat- and acid-stable phosphoprotein (PDGF-associated protein) (PAP) (PDGFA-associated protein 1) (PAP1) PDAP1 HASPP28 Homo sapiens (Human) 181 cell proliferation [GO:0008283]; signal transduction [GO:0007165] GO:0007165; GO:0008283; GO:0044822 0 0 0 PF10252; 468 m.49602 335920 70956.66667 527300.3 72946 83594.5 71560.5 658715.3333 366610 314786 1663998.6 2.819859888 CHOYP_BRAFLDRAFT_118658.2.2 Q13442 m.56465 sp HAP28_HUMAN 66.667 78 25 1 106 183 73 149 1.26E-25 100 HAP28_HUMAN reviewed 28 kDa heat- and acid-stable phosphoprotein (PDGF-associated protein) (PAP) (PDGFA-associated protein 1) (PAP1) PDAP1 HASPP28 Homo sapiens (Human) 181 cell proliferation [GO:0008283]; signal transduction [GO:0007165] GO:0007165; GO:0008283; GO:0044822 0 0 0 PF10252; 469 m.56465 335920 70956.66667 527300.3 72946 83594.5 71560.5 658715.3333 366610 314786 1663998.6 2.819859888 CHOYP_BRAFLDRAFT_206907.11.11 Q9WU49 m.60962 sp CHSP1_RAT 63.063 111 41 0 42 152 30 140 1.32E-44 146 CHSP1_RAT reviewed Calcium-regulated heat stable protein 1 (Calcium-regulated heat-stable protein of 24 kDa) (CRHSP-24) Carhsp1 Rattus norvegicus (Rat) 147 "calcium-mediated signaling [GO:0019722]; regulation of mRNA stability [GO:0043488]; regulation of transcription, DNA-templated [GO:0006355]" GO:0000177; GO:0000932; GO:0003677; GO:0003730; GO:0005737; GO:0005829; GO:0006355; GO:0019722; GO:0043186; GO:0043488; GO:0070062 0 0 cd04458; PF00313; 634 m.60959 443864 37788 324918 282229 407591 151821 650502 390779 2847279.25 315310 2.910799491 CHOYP_BRAFLDRAFT_206907.11.11 Q9WU49 m.60962 sp CHSP1_RAT 63.063 111 41 0 42 152 30 140 1.32E-44 146 CHSP1_RAT reviewed Calcium-regulated heat stable protein 1 (Calcium-regulated heat-stable protein of 24 kDa) (CRHSP-24) Carhsp1 Rattus norvegicus (Rat) 147 "calcium-mediated signaling [GO:0019722]; regulation of mRNA stability [GO:0043488]; regulation of transcription, DNA-templated [GO:0006355]" GO:0000177; GO:0000932; GO:0003677; GO:0003730; GO:0005737; GO:0005829; GO:0006355; GO:0019722; GO:0043186; GO:0043488; GO:0070062 0 0 cd04458; PF00313; 635 m.60961 68645.5 235008 112005.6667 71522.33333 1233161.25 114368.25 71368 76316.5 1437601 241942 1.128609837 CHOYP_BRAFLDRAFT_206907.11.11 Q9WU49 m.60962 sp CHSP1_RAT 63.063 111 41 0 42 152 30 140 1.32E-44 146 CHSP1_RAT reviewed Calcium-regulated heat stable protein 1 (Calcium-regulated heat-stable protein of 24 kDa) (CRHSP-24) Carhsp1 Rattus norvegicus (Rat) 147 "calcium-mediated signaling [GO:0019722]; regulation of mRNA stability [GO:0043488]; regulation of transcription, DNA-templated [GO:0006355]" GO:0000177; GO:0000932; GO:0003677; GO:0003730; GO:0005737; GO:0005829; GO:0006355; GO:0019722; GO:0043186; GO:0043488; GO:0070062 0 0 cd04458; PF00313; 636 m.60962 68645.5 235008 112005.6667 71522.33333 1233161.25 114368.25 71368 76316.5 1437601 241942 1.128609837 CHOYP_BRAFLDRAFT_206907.11.11 Q9Y2V2 m.60961 sp CHSP1_HUMAN 63.063 111 41 0 42 152 30 140 1.97E-44 146 CHSP1_HUMAN reviewed Calcium-regulated heat-stable protein 1 (Calcium-regulated heat-stable protein of 24 kDa) (CRHSP-24) CARHSP1 Homo sapiens (Human) 147 "intracellular signal transduction [GO:0035556]; regulation of mRNA stability [GO:0043488]; regulation of transcription, DNA-templated [GO:0006355]" GO:0000177; GO:0000932; GO:0003677; GO:0003730; GO:0005829; GO:0006355; GO:0019902; GO:0035556; GO:0043186; GO:0043488; GO:0070062 0 0 cd04458; PF00313; 634 m.60959 443864 37788 324918 282229 407591 151821 650502 390779 2847279.25 315310 2.910799491 CHOYP_BRAFLDRAFT_206907.11.11 Q9Y2V2 m.60961 sp CHSP1_HUMAN 63.063 111 41 0 42 152 30 140 1.97E-44 146 CHSP1_HUMAN reviewed Calcium-regulated heat-stable protein 1 (Calcium-regulated heat-stable protein of 24 kDa) (CRHSP-24) CARHSP1 Homo sapiens (Human) 147 "intracellular signal transduction [GO:0035556]; regulation of mRNA stability [GO:0043488]; regulation of transcription, DNA-templated [GO:0006355]" GO:0000177; GO:0000932; GO:0003677; GO:0003730; GO:0005829; GO:0006355; GO:0019902; GO:0035556; GO:0043186; GO:0043488; GO:0070062 0 0 cd04458; PF00313; 635 m.60961 68645.5 235008 112005.6667 71522.33333 1233161.25 114368.25 71368 76316.5 1437601 241942 1.128609837 CHOYP_BRAFLDRAFT_206907.11.11 Q9Y2V2 m.60961 sp CHSP1_HUMAN 63.063 111 41 0 42 152 30 140 1.97E-44 146 CHSP1_HUMAN reviewed Calcium-regulated heat-stable protein 1 (Calcium-regulated heat-stable protein of 24 kDa) (CRHSP-24) CARHSP1 Homo sapiens (Human) 147 "intracellular signal transduction [GO:0035556]; regulation of mRNA stability [GO:0043488]; regulation of transcription, DNA-templated [GO:0006355]" GO:0000177; GO:0000932; GO:0003677; GO:0003730; GO:0005829; GO:0006355; GO:0019902; GO:0035556; GO:0043186; GO:0043488; GO:0070062 0 0 cd04458; PF00313; 636 m.60962 68645.5 235008 112005.6667 71522.33333 1233161.25 114368.25 71368 76316.5 1437601 241942 1.128609837 CHOYP_BRAFLDRAFT_206907.7.11 A4IGP0 m.42201 sp HIKES_XENTR 56.345 197 83 3 1 195 1 196 5.59E-79 237 HIKES_XENTR reviewed Protein Hikeshi 0 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) 197 cellular response to heat [GO:0034605]; protein import into nucleus [GO:0006606]; protein transport [GO:0015031] GO:0005622; GO:0005634; GO:0005829; GO:0006606; GO:0008565; GO:0015031; GO:0030544; GO:0034605 0 0 0 PF05603; 638 m.42200 443864 37788 324918 282229 407591 151821 650502 390779 2847279.25 315310 2.910799491 CHOYP_BRAFLDRAFT_206907.7.11 A4IGP0 m.42201 sp HIKES_XENTR 56.345 197 83 3 1 195 1 196 5.59E-79 237 HIKES_XENTR reviewed Protein Hikeshi 0 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) 197 cellular response to heat [GO:0034605]; protein import into nucleus [GO:0006606]; protein transport [GO:0015031] GO:0005622; GO:0005634; GO:0005829; GO:0006606; GO:0008565; GO:0015031; GO:0030544; GO:0034605 0 0 0 PF05603; 639 m.42201 88459 273432 69648 22989 41091 571497 27582 28415 178057 1015153 3.673596049 CHOYP_BRAFLDRAFT_225253.1.1 O75694 m.9264 sp NU155_HUMAN 49.818 1377 638 13 13 1342 20 1390 0 1373 NU155_HUMAN reviewed Nuclear pore complex protein Nup155 (155 kDa nucleoporin) (Nucleoporin Nup155) NUP155 KIAA0791 Homo sapiens (Human) 1391 atrial cardiac muscle cell action potential [GO:0086014]; gene silencing by RNA [GO:0031047]; intracellular transport of virus [GO:0075733]; mitotic nuclear envelope disassembly [GO:0007077]; mRNA export from nucleus [GO:0006406]; nuclear envelope organization [GO:0006998]; protein import into nucleus [GO:0006606]; protein sumoylation [GO:0016925]; protein targeting to nuclear inner membrane [GO:0036228]; regulation of cellular response to heat [GO:1900034]; regulation of glucose transport [GO:0010827]; RNA export from nucleus [GO:0006405]; transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000972]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083] GO:0000972; GO:0005215; GO:0005635; GO:0006405; GO:0006406; GO:0006409; GO:0006606; GO:0006998; GO:0007077; GO:0010827; GO:0016020; GO:0016032; GO:0016925; GO:0017056; GO:0019083; GO:0031047; GO:0031965; GO:0036228; GO:0044611; GO:0075733; GO:0086014; GO:1900034 0 0 0 PF03177;PF08801; 675 m.9264 186059.2308 388157.3 105924.1 264895.2857 448855.0909 212416.5 261886 230188.6667 329757.4 208958.9286 0.891897206 CHOYP_BRAFLDRAFT_240825.1.1 Q63186 m.43452 sp EI2BD_RAT 55.862 435 176 4 51 485 95 513 4.38E-171 495 EI2BD_RAT reviewed Translation initiation factor eIF-2B subunit delta (eIF-2B GDP-GTP exchange factor subunit delta) Eif2b4 Eif2bd Rattus norvegicus (Rat) 524 cellular response to stimulus [GO:0051716]; hippocampus development [GO:0021766]; myelination [GO:0042552]; negative regulation of guanyl-nucleotide exchange factor activity [GO:1905098]; oligodendrocyte development [GO:0014003]; ovarian follicle development [GO:0001541]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to peptide hormone [GO:0043434]; translational initiation [GO:0006413] GO:0001541; GO:0003743; GO:0005085; GO:0005737; GO:0005851; GO:0006413; GO:0009408; GO:0009749; GO:0014003; GO:0021766; GO:0031369; GO:0042552; GO:0043434; GO:0051716; GO:1905098 0 0 0 PF01008; 691 m.43452 97850 55456 205360 44808 165711 69324 178702 2222357 63820 167561 4.746723824 CHOYP_BRAFLDRAFT_280861.1.2 P12815 m.5389 sp PDCD6_MOUSE 72.455 167 46 0 2 168 24 190 1.13E-89 263 PDCD6_MOUSE reviewed Programmed cell death protein 6 (ALG-257) (PMP41) (Probable calcium-binding protein ALG-2) Pdcd6 Alg2 Mus musculus (Mouse) 191 activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cellular response to heat [GO:0034605]; intracellular protein transport [GO:0006886]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; response to calcium ion [GO:0051592]; vascular endothelial growth factor receptor-2 signaling pathway [GO:0036324] GO:0001525; GO:0001938; GO:0004198; GO:0005509; GO:0005634; GO:0005737; GO:0005768; GO:0005783; GO:0005789; GO:0006886; GO:0006915; GO:0006919; GO:0010595; GO:0030948; GO:0031410; GO:0031965; GO:0032007; GO:0034605; GO:0036324; GO:0042802; GO:0042803; GO:0043280; GO:0043495; GO:0045766; GO:0046983; GO:0048306; GO:0051592; GO:0051898; GO:0060090; GO:0070062; GO:0070971 0 0 0 PF13202;PF13499; 785 m.5389 312306.5 261285.3333 83920.5 606451.5 173257.3333 277223 231069.5 264564.3333 894283.5 200106.5 1.299206327 CHOYP_BRAFLDRAFT_280861.2.2 O75340 m.30165 sp PDCD6_HUMAN 71.257 167 48 0 22 188 24 190 1.32E-89 263 PDCD6_HUMAN reviewed Programmed cell death protein 6 (Apoptosis-linked gene 2 protein) (Probable calcium-binding protein ALG-2) PDCD6 ALG2 Homo sapiens (Human) 191 activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; apoptotic signaling pathway [GO:0097190]; cellular response to heat [GO:0034605]; intracellular protein transport [GO:0006886]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; response to calcium ion [GO:0051592]; vascular endothelial growth factor receptor-2 signaling pathway [GO:0036324] GO:0001525; GO:0001938; GO:0004198; GO:0005509; GO:0005634; GO:0005737; GO:0005768; GO:0005783; GO:0005789; GO:0006886; GO:0006919; GO:0010595; GO:0030948; GO:0031410; GO:0031965; GO:0032007; GO:0034605; GO:0036324; GO:0042802; GO:0043280; GO:0043495; GO:0045766; GO:0046983; GO:0048306; GO:0051592; GO:0051898; GO:0060090; GO:0070062; GO:0070971; GO:0097190 0 0 0 PF13202;PF13499; 786 m.30165 312306.5 261285.3333 83920.5 606451.5 173257.3333 277223 231069.5 264564.3333 894283.5 200106.5 1.299206327 CHOYP_CAN5.1.1 P80404 m.42243 sp GABT_HUMAN 51.02 490 231 2 20 500 9 498 0 534 GABT_HUMAN reviewed "4-aminobutyrate aminotransferase, mitochondrial (EC 2.6.1.19) ((S)-3-amino-2-methylpropionate transaminase) (EC 2.6.1.22) (GABA aminotransferase) (GABA-AT) (Gamma-amino-N-butyrate transaminase) (GABA transaminase) (GABA-T) (L-AIBAT)" ABAT GABAT Homo sapiens (Human) 500 aging [GO:0007568]; behavioral response to cocaine [GO:0048148]; cerebellum development [GO:0021549]; copulation [GO:0007620]; exploration behavior [GO:0035640]; gamma-aminobutyric acid biosynthetic process [GO:0009449]; gamma-aminobutyric acid catabolic process [GO:0009450]; locomotory behavior [GO:0007626]; negative regulation of blood pressure [GO:0045776]; negative regulation of dopamine secretion [GO:0033602]; negative regulation of gamma-aminobutyric acid secretion [GO:0014053]; negative regulation of platelet aggregation [GO:0090331]; neurotransmitter catabolic process [GO:0042135]; positive regulation of aspartate secretion [GO:1904450]; positive regulation of dopamine metabolic process [GO:0045964]; positive regulation of heat generation [GO:0031652]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of insulin secretion [GO:0032024]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of uterine smooth muscle contraction [GO:0070474]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to iron ion [GO:0010039]; response to nicotine [GO:0035094] GO:0001666; GO:0003867; GO:0005739; GO:0005759; GO:0007568; GO:0007620; GO:0007626; GO:0009449; GO:0009450; GO:0010039; GO:0014053; GO:0021549; GO:0030170; GO:0031652; GO:0032024; GO:0032144; GO:0032145; GO:0033602; GO:0035094; GO:0035640; GO:0042135; GO:0042493; GO:0042803; GO:0043005; GO:0045471; GO:0045776; GO:0045964; GO:0046872; GO:0047298; GO:0048148; GO:0051536; GO:0070062; GO:0070474; GO:0090331; GO:0097151; GO:1902722; GO:1904450 0 0 cd00610; PF00202; 1129 m.42242 74657.5 35315.5 148047 192209.3333 141378 163856 251433 299161.5 85572 268028.5 1.805337662 CHOYP_CAN5.1.1 P80404 m.42243 sp GABT_HUMAN 51.02 490 231 2 20 500 9 498 0 534 GABT_HUMAN reviewed "4-aminobutyrate aminotransferase, mitochondrial (EC 2.6.1.19) ((S)-3-amino-2-methylpropionate transaminase) (EC 2.6.1.22) (GABA aminotransferase) (GABA-AT) (Gamma-amino-N-butyrate transaminase) (GABA transaminase) (GABA-T) (L-AIBAT)" ABAT GABAT Homo sapiens (Human) 500 aging [GO:0007568]; behavioral response to cocaine [GO:0048148]; cerebellum development [GO:0021549]; copulation [GO:0007620]; exploration behavior [GO:0035640]; gamma-aminobutyric acid biosynthetic process [GO:0009449]; gamma-aminobutyric acid catabolic process [GO:0009450]; locomotory behavior [GO:0007626]; negative regulation of blood pressure [GO:0045776]; negative regulation of dopamine secretion [GO:0033602]; negative regulation of gamma-aminobutyric acid secretion [GO:0014053]; negative regulation of platelet aggregation [GO:0090331]; neurotransmitter catabolic process [GO:0042135]; positive regulation of aspartate secretion [GO:1904450]; positive regulation of dopamine metabolic process [GO:0045964]; positive regulation of heat generation [GO:0031652]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of insulin secretion [GO:0032024]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of uterine smooth muscle contraction [GO:0070474]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to iron ion [GO:0010039]; response to nicotine [GO:0035094] GO:0001666; GO:0003867; GO:0005739; GO:0005759; GO:0007568; GO:0007620; GO:0007626; GO:0009449; GO:0009450; GO:0010039; GO:0014053; GO:0021549; GO:0030170; GO:0031652; GO:0032024; GO:0032144; GO:0032145; GO:0033602; GO:0035094; GO:0035640; GO:0042135; GO:0042493; GO:0042803; GO:0043005; GO:0045471; GO:0045776; GO:0045964; GO:0046872; GO:0047298; GO:0048148; GO:0051536; GO:0070062; GO:0070474; GO:0090331; GO:0097151; GO:1902722; GO:1904450 0 0 cd00610; PF00202; 1130 m.42243 583881 286334.6667 78863.5 517564.4 49633.25 1178034.5 721463.6667 1482240.5 543327.3333 3179202.4 4.685337349 CHOYP_CARHSP1.1.1 Q9Y2V2 m.11310 sp CHSP1_HUMAN 63.063 111 41 0 21 131 30 140 8.95E-45 146 CHSP1_HUMAN reviewed Calcium-regulated heat-stable protein 1 (Calcium-regulated heat-stable protein of 24 kDa) (CRHSP-24) CARHSP1 Homo sapiens (Human) 147 "intracellular signal transduction [GO:0035556]; regulation of mRNA stability [GO:0043488]; regulation of transcription, DNA-templated [GO:0006355]" GO:0000177; GO:0000932; GO:0003677; GO:0003730; GO:0005829; GO:0006355; GO:0019902; GO:0035556; GO:0043186; GO:0043488; GO:0070062 0 0 cd04458; PF00313; 1146 m.11310 68645.5 235008 112005.6667 71522.33333 1233161.25 114368.25 71368 76316.5 1437601 241942 1.128609837 CHOYP_CH60.1.1 O02649 m.26967 sp CH60_DROME 75.681 551 131 2 1 550 1 549 0 845 CH60_DROME reviewed "60 kDa heat shock protein, mitochondrial (60 kDa chaperonin) (CPN60) (Heat shock protein 60) (HSP-60) (Hsp60) (Mitochondrial matrix protein P1)" Hsp60 Mmp-P1 CG12101 Drosophila melanogaster (Fruit fly) 573 cellular response to heat [GO:0034605]; mitochondrion organization [GO:0007005]; protein refolding [GO:0042026]; sleep [GO:0030431] GO:0005524; GO:0005739; GO:0005743; GO:0005759; GO:0005811; GO:0005875; GO:0007005; GO:0030431; GO:0034605; GO:0042026 0 0 0 PF00118; 1233 m.26967 6208055.704 932557.5263 484718.6818 10698078.26 3768224.429 7787373.25 671226.55 5383351.526 1017431.143 1347014.885 0.733598833 CHOYP_CHGG_10233.1.1 Q4I963 m.39238 sp COFI_GIBZE 39.007 141 84 1 3 141 4 144 4.67E-30 109 COFI_GIBZE reviewed Cofilin (Actin-depolymerizing factor 1) COF1 FGRRES_06245 FGSG_06245 Gibberella zeae (strain PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084) (Wheat head blight fungus) (Fusarium graminearum) 153 actin filament depolymerization [GO:0030042]; actin filament severing [GO:0051014]; cell cycle [GO:0007049]; cell division [GO:0051301]; endocytosis [GO:0006897]; Golgi to plasma membrane protein transport [GO:0043001] GO:0006897; GO:0007049; GO:0016363; GO:0030042; GO:0030479; GO:0043001; GO:0051014; GO:0051301 0 0 cd11286; PF00241; 1239 m.39238 1410350.4 149281.3333 255256.6 45100663.9 681123 256579.6667 549611.8 19005006.14 4548491.5 287565.1667 0.517835629 CHOYP_CLPB.1.3 Q60649 m.14233 sp CLPB_MOUSE 52.007 548 200 6 71 556 118 664 0 556 CLPB_MOUSE reviewed Caseinolytic peptidase B protein homolog (EC 3.6.1.3) (Suppressor of potassium transport defect 3) Clpb Skd3 Mus musculus (Mouse) 677 cellular response to heat [GO:0034605] GO:0005524; GO:0005739; GO:0016887; GO:0034605 0 0 0 PF07724;PF12796;PF10431; 1269 m.14233 58971 1798822.5 84660 45662.5 1775857 58006 100577 3017905.333 7938972.5 194787 3.004869544 CHOYP_CLPB.2.3 Q60649 m.19559 sp CLPB_MOUSE 61.314 548 203 4 90 629 118 664 0 695 CLPB_MOUSE reviewed Caseinolytic peptidase B protein homolog (EC 3.6.1.3) (Suppressor of potassium transport defect 3) Clpb Skd3 Mus musculus (Mouse) 677 cellular response to heat [GO:0034605] GO:0005524; GO:0005739; GO:0016887; GO:0034605 0 0 0 PF07724;PF12796;PF10431; 1270 m.19559 58971 1798822.5 84660 45662.5 1775857 58006 100577 3017905.333 7938972.5 194787 3.004869544 CHOYP_CRYAB.2.5 P04792 m.23200 sp HSPB1_HUMAN 37.234 94 57 2 46 138 89 181 2.28E-09 58.5 HSPB1_HUMAN reviewed Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27) HSPB1 HSP27 HSP28 Homo sapiens (Human) 205 cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028 0 0 0 PF00011; 1763 m.23200 656032.1667 491253.6667 589739.5 275663.5 539560.6667 427730.8333 123881.8333 3278779.125 1646641 558611.7 2.364833254 CHOYP_CRYAB.2.5 P04792 m.23200 sp HSPB1_HUMAN 37.234 94 57 2 46 138 89 181 2.28E-09 58.5 HSPB1_HUMAN reviewed Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27) HSPB1 HSP27 HSP28 Homo sapiens (Human) 205 cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028 0 0 0 PF00011; 1764 m.23201 483273.625 372271.3333 7342004.5 286184.5 542089.5 246745.6667 4659260.889 1075265.714 1637214.4 3352081.083 1.215464473 CHOYP_CRYAB.2.5 P04792 m.23201 sp HSPB1_HUMAN 38.667 75 43 2 49 121 95 168 3.24E-11 61.2 HSPB1_HUMAN reviewed Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27) HSPB1 HSP27 HSP28 Homo sapiens (Human) 205 cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028 0 0 0 PF00011; 1763 m.23200 656032.1667 491253.6667 589739.5 275663.5 539560.6667 427730.8333 123881.8333 3278779.125 1646641 558611.7 2.364833254 CHOYP_CRYAB.2.5 P04792 m.23201 sp HSPB1_HUMAN 38.667 75 43 2 49 121 95 168 3.24E-11 61.2 HSPB1_HUMAN reviewed Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27) HSPB1 HSP27 HSP28 Homo sapiens (Human) 205 cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028 0 0 0 PF00011; 1764 m.23201 483273.625 372271.3333 7342004.5 286184.5 542089.5 246745.6667 4659260.889 1075265.714 1637214.4 3352081.083 1.215464473 CHOYP_DNJA2.1.2 Q2HJ94 m.21835 sp DNJA2_BOVIN 51.643 426 187 5 32 456 5 412 3.87E-136 400 DNJA2_BOVIN reviewed DnaJ homolog subfamily A member 2 DNAJA2 Bos taurus (Bovine) 412 protein refolding [GO:0042026]; response to heat [GO:0009408] GO:0005524; GO:0005829; GO:0009408; GO:0016020; GO:0042026; GO:0046872; GO:0070062 0 0 cd06257; PF00226;PF01556;PF00684; 1895 m.21836 257660.1667 32226.33333 2292822.25 402425 189949.5 126841.25 309064.75 176920.75 370393.3333 587995 0.494857917 CHOYP_DNJC7.1.1 Q99615 m.8987 sp DNJC7_HUMAN 61.983 484 178 4 40 520 14 494 0 550 DNJC7_HUMAN reviewed DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2) DNAJC7 TPR2 TTC2 Homo sapiens (Human) 494 chaperone cofactor-dependent protein refolding [GO:0070389]; protein folding [GO:0006457]; regulation of cellular response to heat [GO:1900034] GO:0001671; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0006457; GO:0016020; GO:0031072; GO:0070062; GO:0070389; GO:1900034 0 0 cd06257; PF00226;PF13414;PF13181; 1898 m.8987 267313.7143 172512 100880.4444 206329.9 253769.2857 212094.1667 150080.1667 92418.125 373871.3636 388994.3846 1.216478522 CHOYP_DPER_GL22446.1.1 P04792 m.52315 sp HSPB1_HUMAN 37.838 74 45 1 28 100 95 168 1.34E-11 61.2 HSPB1_HUMAN reviewed Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27) HSPB1 HSP27 HSP28 Homo sapiens (Human) 205 cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028 0 0 0 PF00011; 1903 m.52311 150372 1061472 56760 1460974 15160 131588.5 1822599 21110 39365 431946 0.891381436 CHOYP_DPER_GL22446.1.1 P04792 m.52315 sp HSPB1_HUMAN 37.838 74 45 1 28 100 95 168 1.34E-11 61.2 HSPB1_HUMAN reviewed Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27) HSPB1 HSP27 HSP28 Homo sapiens (Human) 205 cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028 0 0 0 PF00011; 1904 m.52315 636340 340809.8333 7943169.909 362777.6667 568209 237382.25 5959749.143 1408708.4 1734680.25 4352681.556 1.389988397 CHOYP_GSH1.1.1 P19468 m.8927 sp GSH1_RAT 61.836 621 215 11 1 615 1 605 0 785 GSH1_RAT reviewed Glutamate--cysteine ligase catalytic subunit (EC 6.3.2.2) (GCS heavy chain) (Gamma-ECS) (Gamma-glutamylcysteine synthetase) Gclc Glclc Rattus norvegicus (Rat) 637 "aging [GO:0007568]; apoptotic mitochondrial changes [GO:0008637]; cell redox homeostasis [GO:0045454]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to glucose stimulus [GO:0071333]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to insulin stimulus [GO:0032869]; cellular response to mechanical stimulus [GO:0071260]; cellular response to thyroxine stimulus [GO:0097069]; cysteine metabolic process [GO:0006534]; glutamate metabolic process [GO:0006536]; glutathione biosynthetic process [GO:0006750]; L-ascorbic acid metabolic process [GO:0019852]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of hepatic stellate cell activation [GO:2000490]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; regulation of blood vessel size [GO:0050880]; regulation of mitochondrial depolarization [GO:0051900]; response to activity [GO:0014823]; response to arsenic-containing substance [GO:0046685]; response to cadmium ion [GO:0046686]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to human chorionic gonadotropin [GO:0044752]; response to interleukin-1 [GO:0070555]; response to nitrosative stress [GO:0051409]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to xenobiotic stimulus [GO:0009410]" GO:0000287; GO:0004357; GO:0005524; GO:0005829; GO:0006534; GO:0006536; GO:0006750; GO:0006979; GO:0007568; GO:0007584; GO:0008637; GO:0009408; GO:0009410; GO:0009725; GO:0014823; GO:0016595; GO:0017109; GO:0019852; GO:0031397; GO:0032436; GO:0032869; GO:0035729; GO:0043066; GO:0043524; GO:0043531; GO:0044344; GO:0044752; GO:0045454; GO:0045892; GO:0046685; GO:0046686; GO:0046982; GO:0050662; GO:0050880; GO:0051409; GO:0051900; GO:0070555; GO:0071260; GO:0071333; GO:0071372; GO:0097069; GO:2000490; GO:2001237 PATHWAY: Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 1/2. 0 0 PF03074; 2281 m.8927 1286438.167 275908.8333 275332.2 1057362.25 582170.8 2091339.8 445481.6 1362115 407285.875 7113066.077 3.284035466 CHOYP_HEATR7A.1.1 Q8NDA8 m.6534 sp MROH1_HUMAN 35.358 642 335 9 1 567 224 860 4.26E-126 408 MROH1_HUMAN reviewed Maestro heat-like repeat-containing protein family member 1 (HEAT repeat-containing protein 7A) MROH1 HEATR7A KIAA1833 Homo sapiens (Human) 1641 0 0 0 0 0 PF02985; 2303 m.6534 327289 1769599.5 297140 180639.5 198436.5 158154.5 144782.5 154003 163959.6667 69819.66667 0.249078004 CHOYP_HOW.5.5 O01367 m.58452 sp HOW_DROME 74.479 192 49 0 14 205 77 268 5.62E-98 301 HOW_DROME reviewed Protein held out wings (KH domain protein KH93F) (Protein muscle-specific) (Protein struthio) (Protein wings held out) (Putative RNA-binding protein) (Quaking-related 93F) how KH93F qkr93F stru who CG10293 Drosophila melanogaster (Fruit fly) 405 "apposition of dorsal and ventral imaginal disc-derived wing surfaces [GO:0007475]; axon ensheathment [GO:0008366]; cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; germ-line stem cell population maintenance [GO:0030718]; glial cell migration [GO:0008347]; mesodermal cell migration [GO:0008078]; mesoderm development [GO:0007498]; muscle attachment [GO:0016203]; muscle cell fate determination [GO:0007521]; muscle organ development [GO:0007517]; oenocyte development [GO:0007438]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of embryonic development [GO:0045995]; regulation of heart contraction [GO:0008016]; regulation of translation [GO:0006417]; sarcomere organization [GO:0045214]; somatic muscle development [GO:0007525]; spermatogonial cell division [GO:0007284]" GO:0000381; GO:0003727; GO:0003729; GO:0003730; GO:0005634; GO:0005737; GO:0006417; GO:0007155; GO:0007284; GO:0007438; GO:0007475; GO:0007498; GO:0007517; GO:0007521; GO:0007525; GO:0008016; GO:0008078; GO:0008347; GO:0008366; GO:0016203; GO:0016477; GO:0030154; GO:0030718; GO:0045214; GO:0045995 0 0 0 PF00013;PF16544; 2346 m.58452 53313 343640.5 205400 513767.6667 161731 36488 57108 215143 410181 116829 0.654026359 CHOYP_HSC70.1.1 P63018 m.333 sp HSP7C_RAT 91.213 239 21 0 1 239 314 552 1.72E-154 447 HSP7C_RAT reviewed Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8) Hspa8 Hsc70 Hsc73 Rattus norvegicus (Rat) 646 "aging [GO:0007568]; axo-dendritic transport [GO:0008088]; cellular protein complex disassembly [GO:0043624]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; cerebellum development [GO:0021549]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein folding [GO:0061077]; chaperone mediated protein folding requiring cofactor [GO:0051085]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; clathrin coat disassembly [GO:0072318]; estrous cycle [GO:0044849]; forebrain development [GO:0030900]; G1/S transition of mitotic cell cycle [GO:0000082]; intracellular protein transmembrane import [GO:0044743]; kidney development [GO:0001822]; mRNA processing [GO:0006397]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of catalytic activity [GO:0043085]; positive regulation of gene expression [GO:0010628]; positive regulation of lysosomal membrane permeability [GO:0097214]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein refolding [GO:1904592]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein autophosphorylation [GO:0046777]; protein import into nucleus [GO:0006606]; protein refolding [GO:0042026]; regulation of protein complex stability [GO:0061635]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to nickel cation [GO:0010045]; response to odorant [GO:1990834]; response to progesterone [GO:0032570]; response to starvation [GO:0042594]; RNA splicing [GO:0008380]; sensory perception of smell [GO:0007608]; skeletal muscle tissue development [GO:0007519]; slow axonal transport [GO:1990832]; transcription, DNA-templated [GO:0006351]" GO:0000082; GO:0000974; GO:0001822; GO:0001916; GO:0001917; GO:0003723; GO:0005102; GO:0005524; GO:0005634; GO:0005681; GO:0005730; GO:0005737; GO:0005764; GO:0005765; GO:0005776; GO:0005829; GO:0005874; GO:0005882; GO:0005886; GO:0006351; GO:0006397; GO:0006606; GO:0007519; GO:0007568; GO:0007608; GO:0008021; GO:0008088; GO:0008134; GO:0008380; GO:0009408; GO:0009986; GO:0010045; GO:0010628; GO:0010667; GO:0014069; GO:0014823; GO:0016887; GO:0019899; GO:0021549; GO:0030424; GO:0030425; GO:0030529; GO:0030900; GO:0031686; GO:0032279; GO:0032355; GO:0032570; GO:0034605; GO:0042026; GO:0042277; GO:0042470; GO:0042493; GO:0042594; GO:0042623; GO:0043005; GO:0043025; GO:0043085; GO:0043195; GO:0043197; GO:0043198; GO:0043204; GO:0043234; GO:0043531; GO:0043624; GO:0044743; GO:0044849; GO:0045121; GO:0045471; GO:0045862; GO:0045892; GO:0046777; GO:0048471; GO:0050766; GO:0051082; GO:0051085; GO:0061077; GO:0061635; GO:0061684; GO:0061741; GO:0070062; GO:0071276; GO:0072318; GO:0097214; GO:1903206; GO:1904592; GO:1904593; GO:1904764; GO:1990124; GO:1990832; GO:1990833; GO:1990834; GO:1990836 0 0 0 PF00012; 2367 m.336 53513.75 1728970 423534.5 41421 36153 6633885.75 49827 53835.66667 13072820.71 738965.3333 8.998688124 CHOYP_HSP7C.1.2 P63018 m.22077 sp HSP7C_RAT 80.13 614 121 1 1 614 1 613 0 1028 HSP7C_RAT reviewed Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8) Hspa8 Hsc70 Hsc73 Rattus norvegicus (Rat) 646 "aging [GO:0007568]; axo-dendritic transport [GO:0008088]; cellular protein complex disassembly [GO:0043624]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; cerebellum development [GO:0021549]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein folding [GO:0061077]; chaperone mediated protein folding requiring cofactor [GO:0051085]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; clathrin coat disassembly [GO:0072318]; estrous cycle [GO:0044849]; forebrain development [GO:0030900]; G1/S transition of mitotic cell cycle [GO:0000082]; intracellular protein transmembrane import [GO:0044743]; kidney development [GO:0001822]; mRNA processing [GO:0006397]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of catalytic activity [GO:0043085]; positive regulation of gene expression [GO:0010628]; positive regulation of lysosomal membrane permeability [GO:0097214]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein refolding [GO:1904592]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein autophosphorylation [GO:0046777]; protein import into nucleus [GO:0006606]; protein refolding [GO:0042026]; regulation of protein complex stability [GO:0061635]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to nickel cation [GO:0010045]; response to odorant [GO:1990834]; response to progesterone [GO:0032570]; response to starvation [GO:0042594]; RNA splicing [GO:0008380]; sensory perception of smell [GO:0007608]; skeletal muscle tissue development [GO:0007519]; slow axonal transport [GO:1990832]; transcription, DNA-templated [GO:0006351]" GO:0000082; GO:0000974; GO:0001822; GO:0001916; GO:0001917; GO:0003723; GO:0005102; GO:0005524; GO:0005634; GO:0005681; GO:0005730; GO:0005737; GO:0005764; GO:0005765; GO:0005776; GO:0005829; GO:0005874; GO:0005882; GO:0005886; GO:0006351; GO:0006397; GO:0006606; GO:0007519; GO:0007568; GO:0007608; GO:0008021; GO:0008088; GO:0008134; GO:0008380; GO:0009408; GO:0009986; GO:0010045; GO:0010628; GO:0010667; GO:0014069; GO:0014823; GO:0016887; GO:0019899; GO:0021549; GO:0030424; GO:0030425; GO:0030529; GO:0030900; GO:0031686; GO:0032279; GO:0032355; GO:0032570; GO:0034605; GO:0042026; GO:0042277; GO:0042470; GO:0042493; GO:0042594; GO:0042623; GO:0043005; GO:0043025; GO:0043085; GO:0043195; GO:0043197; GO:0043198; GO:0043204; GO:0043234; GO:0043531; GO:0043624; GO:0044743; GO:0044849; GO:0045121; GO:0045471; GO:0045862; GO:0045892; GO:0046777; GO:0048471; GO:0050766; GO:0051082; GO:0051085; GO:0061077; GO:0061635; GO:0061684; GO:0061741; GO:0070062; GO:0071276; GO:0072318; GO:0097214; GO:1903206; GO:1904592; GO:1904593; GO:1904764; GO:1990124; GO:1990832; GO:1990833; GO:1990834; GO:1990836 0 0 0 PF00012; 2373 m.22077 120382 14295 734687.5 173373 NA 47768 NA 432836 40636 193387 0.685337393 CHOYP_HSP7D.3.3 P63018 m.41777 sp HSP7C_RAT 88.469 529 57 1 1 529 61 585 0 969 HSP7C_RAT reviewed Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8) Hspa8 Hsc70 Hsc73 Rattus norvegicus (Rat) 646 "aging [GO:0007568]; axo-dendritic transport [GO:0008088]; cellular protein complex disassembly [GO:0043624]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; cerebellum development [GO:0021549]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein folding [GO:0061077]; chaperone mediated protein folding requiring cofactor [GO:0051085]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; clathrin coat disassembly [GO:0072318]; estrous cycle [GO:0044849]; forebrain development [GO:0030900]; G1/S transition of mitotic cell cycle [GO:0000082]; intracellular protein transmembrane import [GO:0044743]; kidney development [GO:0001822]; mRNA processing [GO:0006397]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of catalytic activity [GO:0043085]; positive regulation of gene expression [GO:0010628]; positive regulation of lysosomal membrane permeability [GO:0097214]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein refolding [GO:1904592]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein autophosphorylation [GO:0046777]; protein import into nucleus [GO:0006606]; protein refolding [GO:0042026]; regulation of protein complex stability [GO:0061635]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to nickel cation [GO:0010045]; response to odorant [GO:1990834]; response to progesterone [GO:0032570]; response to starvation [GO:0042594]; RNA splicing [GO:0008380]; sensory perception of smell [GO:0007608]; skeletal muscle tissue development [GO:0007519]; slow axonal transport [GO:1990832]; transcription, DNA-templated [GO:0006351]" GO:0000082; GO:0000974; GO:0001822; GO:0001916; GO:0001917; GO:0003723; GO:0005102; GO:0005524; GO:0005634; GO:0005681; GO:0005730; GO:0005737; GO:0005764; GO:0005765; GO:0005776; GO:0005829; GO:0005874; GO:0005882; GO:0005886; GO:0006351; GO:0006397; GO:0006606; GO:0007519; GO:0007568; GO:0007608; GO:0008021; GO:0008088; GO:0008134; GO:0008380; GO:0009408; GO:0009986; GO:0010045; GO:0010628; GO:0010667; GO:0014069; GO:0014823; GO:0016887; GO:0019899; GO:0021549; GO:0030424; GO:0030425; GO:0030529; GO:0030900; GO:0031686; GO:0032279; GO:0032355; GO:0032570; GO:0034605; GO:0042026; GO:0042277; GO:0042470; GO:0042493; GO:0042594; GO:0042623; GO:0043005; GO:0043025; GO:0043085; GO:0043195; GO:0043197; GO:0043198; GO:0043204; GO:0043234; GO:0043531; GO:0043624; GO:0044743; GO:0044849; GO:0045121; GO:0045471; GO:0045862; GO:0045892; GO:0046777; GO:0048471; GO:0050766; GO:0051082; GO:0051085; GO:0061077; GO:0061635; GO:0061684; GO:0061741; GO:0070062; GO:0071276; GO:0072318; GO:0097214; GO:1903206; GO:1904592; GO:1904593; GO:1904764; GO:1990124; GO:1990832; GO:1990833; GO:1990834; GO:1990836 0 0 0 PF00012; 2377 m.41777 120382 14295 734687.5 173373 NA 47768 NA 432836 40636 193387 0.685337393 CHOYP_HSP7D.3.3 P63018 m.41777 sp HSP7C_RAT 88.469 529 57 1 1 529 61 585 0 969 HSP7C_RAT reviewed Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8) Hspa8 Hsc70 Hsc73 Rattus norvegicus (Rat) 646 "aging [GO:0007568]; axo-dendritic transport [GO:0008088]; cellular protein complex disassembly [GO:0043624]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; cerebellum development [GO:0021549]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein folding [GO:0061077]; chaperone mediated protein folding requiring cofactor [GO:0051085]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; clathrin coat disassembly [GO:0072318]; estrous cycle [GO:0044849]; forebrain development [GO:0030900]; G1/S transition of mitotic cell cycle [GO:0000082]; intracellular protein transmembrane import [GO:0044743]; kidney development [GO:0001822]; mRNA processing [GO:0006397]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of catalytic activity [GO:0043085]; positive regulation of gene expression [GO:0010628]; positive regulation of lysosomal membrane permeability [GO:0097214]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein refolding [GO:1904592]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein autophosphorylation [GO:0046777]; protein import into nucleus [GO:0006606]; protein refolding [GO:0042026]; regulation of protein complex stability [GO:0061635]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to nickel cation [GO:0010045]; response to odorant [GO:1990834]; response to progesterone [GO:0032570]; response to starvation [GO:0042594]; RNA splicing [GO:0008380]; sensory perception of smell [GO:0007608]; skeletal muscle tissue development [GO:0007519]; slow axonal transport [GO:1990832]; transcription, DNA-templated [GO:0006351]" GO:0000082; GO:0000974; GO:0001822; GO:0001916; GO:0001917; GO:0003723; GO:0005102; GO:0005524; GO:0005634; GO:0005681; GO:0005730; GO:0005737; GO:0005764; GO:0005765; GO:0005776; GO:0005829; GO:0005874; GO:0005882; GO:0005886; GO:0006351; GO:0006397; GO:0006606; GO:0007519; GO:0007568; GO:0007608; GO:0008021; GO:0008088; GO:0008134; GO:0008380; GO:0009408; GO:0009986; GO:0010045; GO:0010628; GO:0010667; GO:0014069; GO:0014823; GO:0016887; GO:0019899; GO:0021549; GO:0030424; GO:0030425; GO:0030529; GO:0030900; GO:0031686; GO:0032279; GO:0032355; GO:0032570; GO:0034605; GO:0042026; GO:0042277; GO:0042470; GO:0042493; GO:0042594; GO:0042623; GO:0043005; GO:0043025; GO:0043085; GO:0043195; GO:0043197; GO:0043198; GO:0043204; GO:0043234; GO:0043531; GO:0043624; GO:0044743; GO:0044849; GO:0045121; GO:0045471; GO:0045862; GO:0045892; GO:0046777; GO:0048471; GO:0050766; GO:0051082; GO:0051085; GO:0061077; GO:0061635; GO:0061684; GO:0061741; GO:0070062; GO:0071276; GO:0072318; GO:0097214; GO:1903206; GO:1904592; GO:1904593; GO:1904764; GO:1990124; GO:1990832; GO:1990833; GO:1990834; GO:1990836 0 0 0 PF00012; 2378 m.41778 709464.6667 1485667.333 190120 163481.25 707586.75 179798.3333 730063.6667 72929.5 533810.6 487639.6667 0.615492878 CHOYP_HSP7D.3.3 P63018 m.41777 sp HSP7C_RAT 88.469 529 57 1 1 529 61 585 0 969 HSP7C_RAT reviewed Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8) Hspa8 Hsc70 Hsc73 Rattus norvegicus (Rat) 646 "aging [GO:0007568]; axo-dendritic transport [GO:0008088]; cellular protein complex disassembly [GO:0043624]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; cerebellum development [GO:0021549]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein folding [GO:0061077]; chaperone mediated protein folding requiring cofactor [GO:0051085]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; clathrin coat disassembly [GO:0072318]; estrous cycle [GO:0044849]; forebrain development [GO:0030900]; G1/S transition of mitotic cell cycle [GO:0000082]; intracellular protein transmembrane import [GO:0044743]; kidney development [GO:0001822]; mRNA processing [GO:0006397]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of catalytic activity [GO:0043085]; positive regulation of gene expression [GO:0010628]; positive regulation of lysosomal membrane permeability [GO:0097214]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein refolding [GO:1904592]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein autophosphorylation [GO:0046777]; protein import into nucleus [GO:0006606]; protein refolding [GO:0042026]; regulation of protein complex stability [GO:0061635]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to nickel cation [GO:0010045]; response to odorant [GO:1990834]; response to progesterone [GO:0032570]; response to starvation [GO:0042594]; RNA splicing [GO:0008380]; sensory perception of smell [GO:0007608]; skeletal muscle tissue development [GO:0007519]; slow axonal transport [GO:1990832]; transcription, DNA-templated [GO:0006351]" GO:0000082; GO:0000974; GO:0001822; GO:0001916; GO:0001917; GO:0003723; GO:0005102; GO:0005524; GO:0005634; GO:0005681; GO:0005730; GO:0005737; GO:0005764; GO:0005765; GO:0005776; GO:0005829; GO:0005874; GO:0005882; GO:0005886; GO:0006351; GO:0006397; GO:0006606; GO:0007519; GO:0007568; GO:0007608; GO:0008021; GO:0008088; GO:0008134; GO:0008380; GO:0009408; GO:0009986; GO:0010045; GO:0010628; GO:0010667; GO:0014069; GO:0014823; GO:0016887; GO:0019899; GO:0021549; GO:0030424; GO:0030425; GO:0030529; GO:0030900; GO:0031686; GO:0032279; GO:0032355; GO:0032570; GO:0034605; GO:0042026; GO:0042277; GO:0042470; GO:0042493; GO:0042594; GO:0042623; GO:0043005; GO:0043025; GO:0043085; GO:0043195; GO:0043197; GO:0043198; GO:0043204; GO:0043234; GO:0043531; GO:0043624; GO:0044743; GO:0044849; GO:0045121; GO:0045471; GO:0045862; GO:0045892; GO:0046777; GO:0048471; GO:0050766; GO:0051082; GO:0051085; GO:0061077; GO:0061635; GO:0061684; GO:0061741; GO:0070062; GO:0071276; GO:0072318; GO:0097214; GO:1903206; GO:1904592; GO:1904593; GO:1904764; GO:1990124; GO:1990832; GO:1990833; GO:1990834; GO:1990836 0 0 0 PF00012; 2379 m.41779 661583.3 974573.375 383651 626260 514006.3333 291435.375 784412.75 981852.9 2428556.2 198575.9091 1.48250741 CHOYP_HTR5B.1.1 A1A5F2 m.39330 sp HTR5B_XENTR 55.727 2078 850 15 1 2035 1 2051 0 2274 HTR5B_XENTR reviewed HEAT repeat-containing protein 5B heatr5b Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) 2052 0 0 0 0 0 0 2399 m.39330 34446 664023 75276 109310 535418 86445 378203 22322 195884 90597 0.54527016 CHOYP_IF2A.1.1 P68101 m.13279 sp IF2A_RAT 72.787 305 82 1 3 306 4 308 8.15E-165 464 IF2A_RAT reviewed Eukaryotic translation initiation factor 2 subunit 1 (Eukaryotic translation initiation factor 2 subunit alpha) (eIF-2-alpha) (eIF-2A) (eIF-2alpha) Eif2s1 Eif2a Rattus norvegicus (Rat) 315 aging [GO:0007568]; cellular response to amino acid starvation [GO:0034198]; cellular response to heat [GO:0034605]; cellular response to UV [GO:0034644]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of guanyl-nucleotide exchange factor activity [GO:1905098]; negative regulation of translational initiation in response to stress [GO:0032057]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of neuron death [GO:1901216]; positive regulation of type B pancreatic cell apoptotic process [GO:2000676]; protein autophosphorylation [GO:0046777]; response to endoplasmic reticulum stress [GO:0034976]; response to manganese-induced endoplasmic reticulum stress [GO:1990737]; translational initiation [GO:0006413]; xenophagy [GO:0098792] GO:0002230; GO:0003743; GO:0005634; GO:0005737; GO:0005840; GO:0005850; GO:0005851; GO:0006413; GO:0007568; GO:0010494; GO:0016020; GO:0032057; GO:0033290; GO:0034198; GO:0034605; GO:0034644; GO:0034976; GO:0043022; GO:0043614; GO:0044207; GO:0044822; GO:0046777; GO:0070062; GO:0097451; GO:0098779; GO:0098792; GO:1901216; GO:1905098; GO:1990737; GO:2000676 0 0 0 PF07541;PF00575; 2413 m.13279 11019606.4 1964395.333 5446832.167 337367.8 300885.75 200185.2 238561.6667 147715 865800 391535 0.096690357 CHOYP_ISCW_ISCW008219.1.2 P08228 m.46822 sp SODC_MOUSE 70.588 153 45 0 4 156 2 154 1.28E-74 223 SODC_MOUSE reviewed Superoxide dismutase [Cu-Zn] (EC 1.15.1.1) Sod1 Mus musculus (Mouse) 154 activation of MAPK activity [GO:0000187]; aging [GO:0007568]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antibiotic [GO:0046677]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to nutrient levels [GO:0031667]; response to organic substance [GO:0010033]; response to oxidative stress [GO:0006979]; response to reactive oxygen species [GO:0000302]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226] GO:0000187; GO:0000302; GO:0000303; GO:0001541; GO:0001819; GO:0001895; GO:0001975; GO:0002262; GO:0004784; GO:0005507; GO:0005615; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005758; GO:0005764; GO:0005777; GO:0005829; GO:0005886; GO:0006749; GO:0006801; GO:0006879; GO:0006979; GO:0007283; GO:0007566; GO:0007568; GO:0007569; GO:0007605; GO:0007626; GO:0008089; GO:0008090; GO:0008217; GO:0008270; GO:0009408; GO:0010033; GO:0019226; GO:0019430; GO:0030346; GO:0031012; GO:0031045; GO:0031410; GO:0031667; GO:0032287; GO:0032839; GO:0032930; GO:0034465; GO:0035865; GO:0040014; GO:0042493; GO:0042542; GO:0042554; GO:0042802; GO:0043025; GO:0043066; GO:0043085; GO:0043087; GO:0043209; GO:0043234; GO:0043524; GO:0045471; GO:0045541; GO:0045859; GO:0046677; GO:0046688; GO:0046716; GO:0048365; GO:0048678; GO:0050665; GO:0051087; GO:0051881; GO:0060047; GO:0060052; GO:0060087; GO:0060088; GO:0070062; GO:0071276; GO:0071318; GO:0072593; GO:0097332; GO:1902177; GO:1904115 0 0 cd00305; PF00080; 2475 m.46822 3670563.4 468776.25 492295.75 89802.83333 365171.2222 320819.5 281210 369576.8571 1610264.2 335148 0.573470124 CHOYP_ISCW_ISCW008219.2.2 P08228 m.63442 sp SODC_MOUSE 70.588 153 45 0 4 156 2 154 1.28E-74 223 SODC_MOUSE reviewed Superoxide dismutase [Cu-Zn] (EC 1.15.1.1) Sod1 Mus musculus (Mouse) 154 activation of MAPK activity [GO:0000187]; aging [GO:0007568]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antibiotic [GO:0046677]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to nutrient levels [GO:0031667]; response to organic substance [GO:0010033]; response to oxidative stress [GO:0006979]; response to reactive oxygen species [GO:0000302]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226] GO:0000187; GO:0000302; GO:0000303; GO:0001541; GO:0001819; GO:0001895; GO:0001975; GO:0002262; GO:0004784; GO:0005507; GO:0005615; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005758; GO:0005764; GO:0005777; GO:0005829; GO:0005886; GO:0006749; GO:0006801; GO:0006879; GO:0006979; GO:0007283; GO:0007566; GO:0007568; GO:0007569; GO:0007605; GO:0007626; GO:0008089; GO:0008090; GO:0008217; GO:0008270; GO:0009408; GO:0010033; GO:0019226; GO:0019430; GO:0030346; GO:0031012; GO:0031045; GO:0031410; GO:0031667; GO:0032287; GO:0032839; GO:0032930; GO:0034465; GO:0035865; GO:0040014; GO:0042493; GO:0042542; GO:0042554; GO:0042802; GO:0043025; GO:0043066; GO:0043085; GO:0043087; GO:0043209; GO:0043234; GO:0043524; GO:0045471; GO:0045541; GO:0045859; GO:0046677; GO:0046688; GO:0046716; GO:0048365; GO:0048678; GO:0050665; GO:0051087; GO:0051881; GO:0060047; GO:0060052; GO:0060087; GO:0060088; GO:0070062; GO:0071276; GO:0071318; GO:0072593; GO:0097332; GO:1902177; GO:1904115 0 0 cd00305; PF00080; 2476 m.63442 3670563.4 468776.25 492295.75 89802.83333 365171.2222 320819.5 281210 369576.8571 1610264.2 335148 0.573470124 CHOYP_ISCW_ISCW015266.1.1 Q20363 m.57174 sp SIP1_CAEEL 36.25 80 49 2 75 153 49 127 4.57E-09 55.5 SIP1_CAEEL reviewed Stress-induced protein 1 sip-1 F43D9.4 Caenorhabditis elegans 159 determination of adult lifespan [GO:0008340]; embryo development ending in birth or egg hatching [GO:0009792]; multicellular organismal protein metabolic process [GO:0044268]; response to heat [GO:0009408] GO:0005829; GO:0008340; GO:0009408; GO:0009792; GO:0044268; GO:0051082 0 0 0 PF00011; 2511 m.57174 241349 2181351 NA 2039118 NA NA 2655982.5 NA NA 855600 1.180544287 CHOYP_LOC100199246.1.1 Q20363 m.43478 sp SIP1_CAEEL 36.25 80 49 2 204 282 49 127 1.97E-08 55.8 SIP1_CAEEL reviewed Stress-induced protein 1 sip-1 F43D9.4 Caenorhabditis elegans 159 determination of adult lifespan [GO:0008340]; embryo development ending in birth or egg hatching [GO:0009792]; multicellular organismal protein metabolic process [GO:0044268]; response to heat [GO:0009408] GO:0005829; GO:0008340; GO:0009408; GO:0009792; GO:0044268; GO:0051082 0 0 0 PF00011; 2876 m.43478 150372 1061472 56760 1460974 15160 131588.5 1822599 21110 39365 431946 0.891381436 CHOYP_LOC100211409.1.1 P04792 m.4742 sp HSPB1_HUMAN 38.667 75 43 2 161 233 95 168 3.82E-10 60.8 HSPB1_HUMAN reviewed Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27) HSPB1 HSP27 HSP28 Homo sapiens (Human) 205 cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028 0 0 0 PF00011; 2894 m.4742 651414.5556 337618.1 6317623.786 378199.4438 467184 338760.75 3826765.727 2681237.5 1244984.25 2706129.875 1.324561491 CHOYP_LOC100211409.1.1 P04792 m.4743 sp HSPB1_HUMAN 32.099 81 54 1 46 125 89 169 1.88E-06 50.1 HSPB1_HUMAN reviewed Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27) HSPB1 HSP27 HSP28 Homo sapiens (Human) 205 cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028 0 0 0 PF00011; 2894 m.4742 651414.5556 337618.1 6317623.786 378199.4438 467184 338760.75 3826765.727 2681237.5 1244984.25 2706129.875 1.324561491 CHOYP_LOC100358262.2.3 P35244 m.28381 sp RFA3_HUMAN 40.678 118 69 1 1 118 4 120 3.27E-27 100 RFA3_HUMAN reviewed Replication protein A 14 kDa subunit (RP-A p14) (Replication factor A protein 3) (RF-A protein 3) RPA3 REPA3 RPA14 Homo sapiens (Human) 121 "base-excision repair [GO:0006284]; DNA damage response, detection of DNA damage [GO:0042769]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; G1/S transition of mitotic cell cycle [GO:0000082]; interstrand cross-link repair [GO:0036297]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; regulation of cell proliferation [GO:0042127]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; telomere maintenance via recombination [GO:0000722]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]" GO:0000082; GO:0000722; GO:0000724; GO:0003684; GO:0003697; GO:0005654; GO:0005662; GO:0006260; GO:0006283; GO:0006284; GO:0006289; GO:0006293; GO:0006294; GO:0006295; GO:0006296; GO:0006297; GO:0006298; GO:0007346; GO:0019985; GO:0033683; GO:0036297; GO:0042127; GO:0042276; GO:0042769; GO:0070987; GO:1900034; GO:1901796 0 0 0 PF08661; 2930 m.28381 36908 141738.5 448794 4948323.667 581128.5 565290 996840 1904431 2768083 NA 1.265785425 CHOYP_LOC100368486.1.1 O95433 m.18263 sp AHSA1_HUMAN 44.058 345 186 3 1 345 1 338 1.20E-106 318 AHSA1_HUMAN reviewed Activator of 90 kDa heat shock protein ATPase homolog 1 (AHA1) (p38) AHSA1 C14orf3 HSPC322 Homo sapiens (Human) 338 response to stress [GO:0006950] GO:0001671; GO:0005737; GO:0005783; GO:0005829; GO:0005913; GO:0006950; GO:0051087; GO:0070062; GO:0098641 0 0 0 PF09229;PF08327; 3067 m.18263 215968.5714 268639.4 1098960 318909.8889 85470.4 599456.6667 113610 145458.375 1112724.889 199669.5 1.092040208 CHOYP_LOC100370246.2.2 Q13442 m.45836 sp HAP28_HUMAN 66.667 78 25 1 91 168 73 149 1.50E-25 100 HAP28_HUMAN reviewed 28 kDa heat- and acid-stable phosphoprotein (PDGF-associated protein) (PAP) (PDGFA-associated protein 1) (PAP1) PDAP1 HASPP28 Homo sapiens (Human) 181 cell proliferation [GO:0008283]; signal transduction [GO:0007165] GO:0007165; GO:0008283; GO:0044822 0 0 0 PF10252; 3152 m.45834 353230 71983.5 373997.5 51339 659856 157121.3333 2798705.25 163554.5 346243 7064094.553 6.971449158 CHOYP_LOC100370246.2.2 Q13442 m.45836 sp HAP28_HUMAN 66.667 78 25 1 91 168 73 149 1.50E-25 100 HAP28_HUMAN reviewed 28 kDa heat- and acid-stable phosphoprotein (PDGF-associated protein) (PAP) (PDGFA-associated protein 1) (PAP1) PDAP1 HASPP28 Homo sapiens (Human) 181 cell proliferation [GO:0008283]; signal transduction [GO:0007165] GO:0007165; GO:0008283; GO:0044822 0 0 0 PF10252; 3153 m.45836 335920 70956.66667 527300.3 72946 83594.5 71560.5 658715.3333 366610 314786 1663998.6 2.819859888 CHOYP_LOC100371881.1.2 E9PVX6 m.3634 sp KI67_MOUSE 49.541 109 55 0 6 114 7 115 4.56E-29 131 KI67_MOUSE reviewed Proliferation marker protein Ki-67 (Antigen identified by monoclonal antibody Ki-67 homolog) (Antigen KI-67 homolog) (Antigen Ki67 homolog) Mki67 Mus musculus (Mouse) 3177 cell proliferation [GO:0008283]; cellular response to heat [GO:0034605]; cholangiocyte proliferation [GO:1990705]; DNA metabolic process [GO:0006259]; hepatocyte proliferation [GO:0072574]; hyaluronan metabolic process [GO:0030212]; meiotic nuclear division [GO:0007126]; organ regeneration [GO:0031100]; response to organic cyclic compound [GO:0014070] GO:0000775; GO:0000793; GO:0005634; GO:0005730; GO:0005737; GO:0006259; GO:0007126; GO:0008022; GO:0008283; GO:0014070; GO:0016020; GO:0030212; GO:0031100; GO:0034605; GO:0044822; GO:0072574; GO:1990705 0 0 0 PF00498;PF08065;PF15276; 3233 m.3634 414605.4091 940514.9412 1138740.963 942008.5 561584.1818 744479.36 290809.9655 182972.5 2162864.077 2741102.35 1.531531885 CHOYP_LOC100371881.2.2 E9PVX6 m.12634 sp KI67_MOUSE 49.091 110 56 0 5 114 6 115 3.69E-29 131 KI67_MOUSE reviewed Proliferation marker protein Ki-67 (Antigen identified by monoclonal antibody Ki-67 homolog) (Antigen KI-67 homolog) (Antigen Ki67 homolog) Mki67 Mus musculus (Mouse) 3177 cell proliferation [GO:0008283]; cellular response to heat [GO:0034605]; cholangiocyte proliferation [GO:1990705]; DNA metabolic process [GO:0006259]; hepatocyte proliferation [GO:0072574]; hyaluronan metabolic process [GO:0030212]; meiotic nuclear division [GO:0007126]; organ regeneration [GO:0031100]; response to organic cyclic compound [GO:0014070] GO:0000775; GO:0000793; GO:0005634; GO:0005730; GO:0005737; GO:0006259; GO:0007126; GO:0008022; GO:0008283; GO:0014070; GO:0016020; GO:0030212; GO:0031100; GO:0034605; GO:0044822; GO:0072574; GO:1990705 0 0 0 PF00498;PF08065;PF15276; 3234 m.12634 445166.2105 276503.75 1186197 1055477.45 553754.0588 826196.7727 315013.56 185771.2353 1055123.667 2860348.842 1.490562213 CHOYP_LOC100374573.1.1 P31689 m.24523 sp DNJA1_HUMAN 65.594 404 125 5 1 398 1 396 4.75E-179 506 DNJA1_HUMAN reviewed DnaJ homolog subfamily A member 1 (DnaJ protein homolog 2) (HSDJ) (Heat shock 40 kDa protein 4) (Heat shock protein J2) (HSJ-2) (Human DnaJ protein 2) (hDj-2) DNAJA1 DNAJ2 HDJ2 HSJ2 HSPF4 Homo sapiens (Human) 397 "androgen receptor signaling pathway [GO:0030521]; DNA damage response, detection of DNA damage [GO:0042769]; negative regulation of apoptotic process [GO:0043066]; negative regulation of establishment of protein localization to mitochondrion [GO:1903748]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway [GO:1905259]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of apoptotic process [GO:0043065]; protein folding [GO:0006457]; protein localization to mitochondrion [GO:0070585]; regulation of protein transport [GO:0051223]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; spermatogenesis [GO:0007283]; sperm motility [GO:0030317]; toxin transport [GO:1901998]" GO:0001664; GO:0005524; GO:0005634; GO:0005739; GO:0005829; GO:0006457; GO:0006986; GO:0007283; GO:0009408; GO:0016020; GO:0030317; GO:0030521; GO:0030544; GO:0030957; GO:0031397; GO:0031625; GO:0042769; GO:0043065; GO:0043066; GO:0043508; GO:0046872; GO:0048471; GO:0050750; GO:0051087; GO:0051223; GO:0055131; GO:0070062; GO:0070585; GO:0098554; GO:1901998; GO:1903748; GO:1905259 0 0 cd06257; PF00226;PF01556;PF00684; 3405 m.24523 309802.2 353796.6667 79159 386589.25 1288476.2 1920633.333 342487 276688 117232 4563791.667 2.986501102 CHOYP_LOC100375678.1.1 P70541 m.51537 sp EI2BG_RAT 41.111 450 255 5 1 446 1 444 1.08E-119 360 EI2BG_RAT reviewed Translation initiation factor eIF-2B subunit gamma (eIF-2B GDP-GTP exchange factor subunit gamma) Eif2b3 Eif2bg Rattus norvegicus (Rat) 452 cellular response to stimulus [GO:0051716]; hippocampus development [GO:0021766]; oligodendrocyte development [GO:0014003]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to peptide hormone [GO:0043434]; translation [GO:0006412]; translational initiation [GO:0006413] GO:0003743; GO:0005085; GO:0005737; GO:0005851; GO:0006412; GO:0006413; GO:0009408; GO:0009749; GO:0014003; GO:0016779; GO:0021766; GO:0043434; GO:0051716 0 0 0 PF00483; 3496 m.51537 230464 768359.5 140402 53685.25 157880 417747 29487 48654 58939.5 388500.75 0.698352613 CHOYP_LOC100375762.1.1 Q21313 m.3921 sp EPI1_CAEEL 35.632 174 99 7 12 182 3002 3165 3.45E-14 74.3 EPI1_CAEEL reviewed Laminin-like protein epi-1 epi-1 K08C7.3 Caenorhabditis elegans 3672 axonal defasciculation [GO:0007414]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; neuron migration [GO:0001764]; positive regulation of endopeptidase activity [GO:0010950]; positive regulation of locomotion [GO:0040017]; regulation of cell proliferation [GO:0042127]; reproduction [GO:0000003]; response to heat [GO:0009408]; response to misfolded protein [GO:0051788] GO:0000003; GO:0001764; GO:0005604; GO:0007155; GO:0007414; GO:0009408; GO:0010950; GO:0016477; GO:0040017; GO:0042127; GO:0051788; GO:0071711 0 0 0 PF00052;PF00053;PF00054;PF02210;PF06009;PF00055; 3498 m.3921 1596999.333 4182192 201329 52276 89294 645973 453889 916246 991501.5 702682.3333 0.606049835 CHOYP_LOC100377173.1.2 P04792 m.37699 sp HSPB1_HUMAN 38.667 75 43 2 161 233 95 168 1.68E-09 59.3 HSPB1_HUMAN reviewed Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27) HSPB1 HSP27 HSP28 Homo sapiens (Human) 205 cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028 0 0 0 PF00011; 3596 m.37698 2755969.8 72264.1 698586.8667 685428.0769 198614.6667 379931.6667 524564.4615 294265.0833 1047699.833 1460404.467 0.840394518 CHOYP_LOC100377173.1.2 P04792 m.37699 sp HSPB1_HUMAN 38.667 75 43 2 161 233 95 168 1.68E-09 59.3 HSPB1_HUMAN reviewed Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27) HSPB1 HSP27 HSP28 Homo sapiens (Human) 205 cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028 0 0 0 PF00011; 3597 m.37699 651414.5556 337618.1 6317623.786 378199.4438 467184 338760.75 3826765.727 2681237.5 1244984.25 2706129.875 1.324561491 CHOYP_LOC100561123.26.28 Q99933 m.57595 sp BAG1_HUMAN 36.842 171 107 1 43 213 170 339 2.34E-29 114 BAG1_HUMAN reviewed BAG family molecular chaperone regulator 1 (BAG-1) (Bcl-2-associated athanogene 1) BAG1 HAP Homo sapiens (Human) 345 apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0070389]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034] GO:0000774; GO:0005057; GO:0005634; GO:0005737; GO:0005829; GO:0006915; GO:0007166; GO:0043066; GO:0070389; GO:1900034 0 0 0 PF02179;PF00240; 3804 m.57595 1066671 1436990.5 46641 2873231.25 648607 549186.75 910454 1409270.5 4610789.5 1159230 1.422715827 CHOYP_LOC100696358.1.1 P30946 m.27371 sp HS90A_RABIT 80.336 417 62 3 7 423 12 408 0 668 HS90A_RABIT reviewed Heat shock protein HSP 90-alpha HSP90AA1 HSPCA Oryctolagus cuniculus (Rabbit) 694 protein folding [GO:0006457]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408] GO:0005524; GO:0005634; GO:0005737; GO:0005886; GO:0006457; GO:0009408; GO:0009409; GO:0042470; GO:0046677 0 0 0 PF02518;PF00183; 3917 m.27370 274228 860776.5 309889 1043447.333 409178 102018.6667 283799 201022.5 1549111 73198 0.762427889 CHOYP_LOC100696358.1.1 P30946 m.27371 sp HS90A_RABIT 80.336 417 62 3 7 423 12 408 0 668 HS90A_RABIT reviewed Heat shock protein HSP 90-alpha HSP90AA1 HSPCA Oryctolagus cuniculus (Rabbit) 694 protein folding [GO:0006457]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408] GO:0005524; GO:0005634; GO:0005737; GO:0005886; GO:0006457; GO:0009408; GO:0009409; GO:0042470; GO:0046677 0 0 0 PF02518;PF00183; 3918 m.27371 4283461.826 2286485.636 761342.6667 5735210.091 5186704.818 5146968.85 6657960.619 3454415.476 19866128.32 4696025.308 2.18161679 CHOYP_LOC100704237.1.2 Q96A56 m.6766 sp T53I1_HUMAN 29.518 166 98 8 24 181 85 239 6.24E-07 51.2 T53I1_HUMAN reviewed Tumor protein p53-inducible nuclear protein 1 (Stress-induced protein) (p53-dependent damage-inducible nuclear protein 1) (p53DINP1) TP53INP1 P53DINP1 SIP Homo sapiens (Human) 240 "apoptotic process [GO:0006915]; autophagic cell death [GO:0048102]; autophagosome assembly [GO:0000045]; cell cycle arrest [GO:0007050]; cellular response to ethanol [GO:0071361]; cellular response to hydroperoxide [GO:0071447]; cellular response to methyl methanesulfonate [GO:0072703]; cellular response to UV [GO:0034644]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of autophagy [GO:0010508]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of apoptotic process [GO:0042981]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to heat [GO:0009408]; response to stress [GO:0006950]; transcription, DNA-templated [GO:0006351]" GO:0000045; GO:0005634; GO:0005654; GO:0005737; GO:0005776; GO:0005829; GO:0006351; GO:0006915; GO:0006950; GO:0007050; GO:0008285; GO:0009408; GO:0010508; GO:0016209; GO:0016605; GO:0030336; GO:0031410; GO:0034644; GO:0042981; GO:0045893; GO:0048102; GO:0071361; GO:0071447; GO:0072703; GO:1901796; GO:2001235 0 0 0 PF14839; 3941 m.6768 507306 NA 171624 110176 46699 514788 56250 84206 151401 515857 1.265847417 CHOYP_LOC100863781.1.1 P20241 m.33751 sp NRG_DROME 29.283 1284 780 43 26 1257 28 1235 5.28E-133 443 NRG_DROME reviewed Neuroglian Nrg CG1634 Drosophila melanogaster (Fruit fly) 1302 "axon ensheathment [GO:0008366]; axon extension [GO:0048675]; axonogenesis [GO:0007409]; cell adhesion involved in heart morphogenesis [GO:0061343]; central complex development [GO:0048036]; dendrite morphogenesis [GO:0048813]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of glial blood-brain barrier [GO:0060857]; female courtship behavior [GO:0008050]; imaginal disc morphogenesis [GO:0007560]; male courtship behavior [GO:0008049]; melanotic encapsulation of foreign target [GO:0035011]; motor neuron axon guidance [GO:0008045]; mushroom body development [GO:0016319]; nerve maturation [GO:0021682]; neuron cell-cell adhesion [GO:0007158]; neuron projection morphogenesis [GO:0048812]; photoreceptor cell axon guidance [GO:0072499]; regulation of female receptivity [GO:0045924]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]; synapse organization [GO:0050808]" GO:0005509; GO:0005886; GO:0005918; GO:0005919; GO:0005923; GO:0007158; GO:0007173; GO:0007409; GO:0007560; GO:0008045; GO:0008049; GO:0008050; GO:0008366; GO:0016021; GO:0016319; GO:0016328; GO:0019991; GO:0021682; GO:0030175; GO:0035011; GO:0035151; GO:0045924; GO:0048036; GO:0048675; GO:0048812; GO:0048813; GO:0050808; GO:0060857; GO:0061343; GO:0072499 0 0 0 PF13882;PF00041;PF07679;PF00047; 4041 m.33751 199308.7778 883001.8571 965261.2222 542803.875 1057214 220068.6923 381349.5 7608617.875 2295522.538 144285 2.919693383 CHOYP_LOC100897892.1.1 P82147 m.1462 sp L2EFL_DROME 45.055 91 47 2 84 172 76 165 8.31E-16 74.7 L2EFL_DROME reviewed Protein lethal(2)essential for life (Protein Efl21) l(2)efl CG4533 Drosophila melanogaster (Fruit fly) 187 multicellular organism development [GO:0007275]; protein refolding [GO:0042026]; regulation of translational initiation by eIF2 alpha phosphorylation [GO:0010998]; response to heat [GO:0009408]; sarcomere organization [GO:0045214] GO:0007275; GO:0009408; GO:0010998; GO:0030018; GO:0042026; GO:0045214; GO:0048471 0 0 0 PF00011; 4152 m.1462 147038 54459.33333 391632 272975.3333 227513 404633.6 136895.25 326237.75 864669.5556 56337.16667 1.635647793 CHOYP_LOC100902807.1.4 Q9VN14 m.12152 sp CONT_DROME 30.047 1278 764 32 26 1230 139 1359 8.93E-172 550 CONT_DROME reviewed Contactin Cont CG1084 Drosophila melanogaster (Fruit fly) 1390 axon ensheathment [GO:0008366]; cell adhesion involved in heart morphogenesis [GO:0061343]; establishment of glial blood-brain barrier [GO:0060857]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; nerve maturation [GO:0021682]; septate junction assembly [GO:0019991] GO:0005886; GO:0005918; GO:0008366; GO:0019991; GO:0021682; GO:0031225; GO:0045197; GO:0060857; GO:0061343 0 0 0 PF00041;PF00047;PF00059; 4168 m.12152 77827 232536 29642 83736 598089 23468 100225 312367 12157518.33 13208567.5 25.25091828 CHOYP_LOC100902807.4.4 Q9VN14 m.59166 sp CONT_DROME 29.476 1106 675 26 153 1224 323 1357 1.62E-139 462 CONT_DROME reviewed Contactin Cont CG1084 Drosophila melanogaster (Fruit fly) 1390 axon ensheathment [GO:0008366]; cell adhesion involved in heart morphogenesis [GO:0061343]; establishment of glial blood-brain barrier [GO:0060857]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; nerve maturation [GO:0021682]; septate junction assembly [GO:0019991] GO:0005886; GO:0005918; GO:0008366; GO:0019991; GO:0021682; GO:0031225; GO:0045197; GO:0060857; GO:0061343 0 0 0 PF00041;PF00047;PF00059; 4169 m.59166 418992.5 390671.6 1232350.75 248297.3333 324351.7143 3908380.667 1107983.2 185518 3206126.556 131615 3.266050153 CHOYP_LOC101416772.1.1 Q9W6X3 m.30815 sp CH10_ORYLA 72.917 96 26 0 38 133 2 97 4.12E-45 145 CH10_ORYLA reviewed "10 kDa heat shock protein, mitochondrial (Hsp10) (10 kDa chaperonin) (Chaperonin 10) (CPN10)" hspe1 hsp10 Oryzias latipes (Japanese rice fish) (Japanese killifish) 99 protein folding [GO:0006457] GO:0005524; GO:0005759; GO:0006457 0 0 cd00320; PF00166; 4330 m.30815 92004 101511 33772 30870 194897 NA 212289 54063 116328 183264 1.561469494 CHOYP_LOC579737.1.1 Q64350 m.14356 sp EI2BE_RAT 40.087 686 376 12 30 687 38 716 7.49E-164 491 EI2BE_RAT reviewed Translation initiation factor eIF-2B subunit epsilon (eIF-2B GDP-GTP exchange factor subunit epsilon) Eif2b5 Eif2be Rattus norvegicus (Rat) 716 aging [GO:0007568]; astrocyte development [GO:0014002]; astrocyte differentiation [GO:0048708]; cellular response to drug [GO:0035690]; hippocampus development [GO:0021766]; myelination [GO:0042552]; oligodendrocyte development [GO:0014003]; ovarian follicle development [GO:0001541]; positive regulation of apoptotic process [GO:0043065]; positive regulation of translation [GO:0045727]; positive regulation of translational initiation [GO:0045948]; response to endoplasmic reticulum stress [GO:0034976]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to lithium ion [GO:0010226]; response to peptide hormone [GO:0043434]; translational initiation [GO:0006413] GO:0001541; GO:0003743; GO:0005085; GO:0005634; GO:0005737; GO:0005851; GO:0006413; GO:0007568; GO:0009408; GO:0009749; GO:0010226; GO:0014002; GO:0014003; GO:0021766; GO:0031369; GO:0034976; GO:0035690; GO:0042552; GO:0043065; GO:0043434; GO:0045727; GO:0045948; GO:0048708 0 0 0 PF00132;PF02020; 4435 m.14356 2481403 917910.5 448945.75 408889 34092 755422.6 839856.4 2704728 1576041.333 2507937.75 1.953744278 CHOYP_LOC585338.2.2 Q13442 m.40817 sp HAP28_HUMAN 66.667 78 25 1 91 168 73 149 1.50E-25 100 HAP28_HUMAN reviewed 28 kDa heat- and acid-stable phosphoprotein (PDGF-associated protein) (PAP) (PDGFA-associated protein 1) (PAP1) PDAP1 HASPP28 Homo sapiens (Human) 181 cell proliferation [GO:0008283]; signal transduction [GO:0007165] GO:0007165; GO:0008283; GO:0044822 0 0 0 PF10252; 4492 m.40816 52371744.25 16094800.65 19517021.64 7164769.824 29898509 37188397.04 38080610.67 25194416.09 95942565.82 31823891.32 1.825155047 CHOYP_LOC585338.2.2 Q13442 m.40817 sp HAP28_HUMAN 66.667 78 25 1 91 168 73 149 1.50E-25 100 HAP28_HUMAN reviewed 28 kDa heat- and acid-stable phosphoprotein (PDGF-associated protein) (PAP) (PDGFA-associated protein 1) (PAP1) PDAP1 HASPP28 Homo sapiens (Human) 181 cell proliferation [GO:0008283]; signal transduction [GO:0007165] GO:0007165; GO:0008283; GO:0044822 0 0 0 PF10252; 4493 m.40817 335920 70956.66667 527300.3 72946 83594.5 71560.5 658715.3333 366610 314786 1663998.6 2.819859888 CHOYP_LOC752244.2.2 Q9UDY4 m.45622 sp DNJB4_HUMAN 56.667 360 127 3 1 354 1 337 4.87E-132 383 DNJB4_HUMAN reviewed DnaJ homolog subfamily B member 4 (Heat shock 40 kDa protein 1 homolog) (HSP40 homolog) (Heat shock protein 40 homolog) (Human liver DnaJ-like protein) DNAJB4 DNAJW HLJ1 Homo sapiens (Human) 337 protein folding [GO:0006457]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986] GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0006457; GO:0006986; GO:0009408; GO:0051082; GO:0051087; GO:0070062 0 0 cd06257; PF00226;PF01556; 4697 m.45622 78111.16667 82843.25 1222879.333 227167.6 18023780 82598.25 196811 34118.75 410695.25 55038209.44 2.839982361 CHOYP_MROH1.1.1 Q8NDA8 m.24366 sp MROH1_HUMAN 36.659 1664 1007 15 14 1656 2 1639 0 1130 MROH1_HUMAN reviewed Maestro heat-like repeat-containing protein family member 1 (HEAT repeat-containing protein 7A) MROH1 HEATR7A KIAA1833 Homo sapiens (Human) 1641 0 0 0 0 0 PF02985; 4869 m.24366 175576.7778 439130.6 549810 112292.6 291701.3333 263226.6154 261635.6 218251.4545 1102237.583 360383.5556 1.406260059 CHOYP_MROH1.1.1 Q8NDA8 m.24366 sp MROH1_HUMAN 36.659 1664 1007 15 14 1656 2 1639 0 1130 MROH1_HUMAN reviewed Maestro heat-like repeat-containing protein family member 1 (HEAT repeat-containing protein 7A) MROH1 HEATR7A KIAA1833 Homo sapiens (Human) 1641 0 0 0 0 0 PF02985; 4870 m.24367 4419513.45 2397297.077 2898510.769 715977.4545 5065120.625 3004401.467 2882539.467 488953.875 305500.1333 1917694.563 0.554908156 CHOYP_MTOR.2.2 P42345 m.51573 sp MTOR_HUMAN 64.88 2537 818 16 8 2479 21 2549 0 3351 MTOR_HUMAN reviewed Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin and FKBP12 target 1) (Rapamycin target protein 1) MTOR FRAP FRAP1 FRAP2 RAFT1 RAPT1 Homo sapiens (Human) 2549 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; brain development [GO:0007420]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell growth [GO:0016049]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient levels [GO:0031669]; DNA repair [GO:0006281]; energy reserve metabolic process [GO:0006112]; germ cell development [GO:0007281]; growth [GO:0040007]; heart morphogenesis [GO:0003007]; heart valve morphogenesis [GO:0003179]; long-term memory [GO:0007616]; macroautophagy [GO:0016236]; maternal process involved in female pregnancy [GO:0060135]; mRNA stabilization [GO:0048255]; multicellular organism growth [GO:0035264]; negative regulation of autophagy [GO:0010507]; negative regulation of cell size [GO:0045792]; negative regulation of cholangiocyte apoptotic process [GO:1904193]; negative regulation of iodide transmembrane transport [GO:1904213]; negative regulation of macroautophagy [GO:0016242]; negative regulation of muscle atrophy [GO:0014736]; negative regulation of NFAT protein import into nucleus [GO:0051534]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein ubiquitination [GO:0031397]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphorylation [GO:0016310]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of eating behavior [GO:1904000]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulosa cell proliferation [GO:1904197]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of myotube differentiation [GO:0010831]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron maturation [GO:0014042]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of sensory perception of pain [GO:1904058]; positive regulation of skeletal muscle hypertrophy [GO:1904206]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of transcription from RNA polymerase III promoter [GO:0045945]; positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter [GO:1901838]; positive regulation of translation [GO:0045727]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein catabolic process [GO:0030163]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of brown fat cell differentiation [GO:0090335]; regulation of carbohydrate utilization [GO:0043610]; regulation of cellular response to heat [GO:1900034]; regulation of fatty acid beta-oxidation [GO:0031998]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of GTPase activity [GO:0043087]; regulation of membrane permeability [GO:0090559]; regulation of myelination [GO:0031641]; regulation of osteoclast differentiation [GO:0045670]; regulation of protein kinase activity [GO:0045859]; regulation of response to food [GO:0032095]; response to amino acid [GO:0043200]; response to cocaine [GO:0042220]; response to insulin [GO:0032868]; response to morphine [GO:0043278]; response to nutrient [GO:0007584]; response to stress [GO:0006950]; ruffle organization [GO:0031529]; signal transduction [GO:0007165]; social behavior [GO:0035176]; spinal cord development [GO:0021510]; T cell costimulation [GO:0031295]; TOR signaling [GO:0031929]; visual learning [GO:0008542]; voluntary musculoskeletal movement [GO:0050882]; wound healing [GO:0042060] GO:0000139; GO:0001030; GO:0001031; GO:0001032; GO:0001156; GO:0001933; GO:0001934; GO:0001938; GO:0003007; GO:0003179; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005741; GO:0005764; GO:0005765; GO:0005789; GO:0005829; GO:0005942; GO:0005979; GO:0006112; GO:0006207; GO:0006281; GO:0006468; GO:0006950; GO:0007050; GO:0007165; GO:0007281; GO:0007420; GO:0007569; GO:0007584; GO:0007616; GO:0008542; GO:0009791; GO:0010507; GO:0010592; GO:0010628; GO:0010831; GO:0012505; GO:0014042; GO:0014736; GO:0016020; GO:0016049; GO:0016236; GO:0016242; GO:0016301; GO:0016310; GO:0016605; GO:0018105; GO:0018107; GO:0021510; GO:0030163; GO:0030425; GO:0030838; GO:0031295; GO:0031397; GO:0031529; GO:0031641; GO:0031669; GO:0031929; GO:0031931; GO:0031932; GO:0031998; GO:0032095; GO:0032868; GO:0032956; GO:0035176; GO:0035264; GO:0040007; GO:0042060; GO:0042220; GO:0043022; GO:0043025; GO:0043087; GO:0043200; GO:0043278; GO:0043610; GO:0045429; GO:0045670; GO:0045727; GO:0045792; GO:0045859; GO:0045945; GO:0046777; GO:0046889; GO:0048015; GO:0048255; GO:0048661; GO:0048714; GO:0050731; GO:0050882; GO:0051219; GO:0051496; GO:0051534; GO:0051897; GO:0055013; GO:0060048; GO:0060135; GO:0060252; GO:0060999; GO:0061051; GO:0071456; GO:0090335; GO:0090559; GO:1900034; GO:1901216; GO:1901838; GO:1904000; GO:1904056; GO:1904058; GO:1904193; GO:1904197; GO:1904206; GO:1904213 0 0 0 PF11865;PF02259;PF02260;PF08771;PF00454; 4888 m.51573 134636.5 101621 83347 141601 109201 144805.5 56245 409431.5 1509876.333 22049 3.755930784 CHOYP_MYOF.2.3 Q69ZN7 m.15277 sp MYOF_MOUSE 47.696 2105 987 32 3 2055 2 2044 0 1870 MYOF_MOUSE reviewed Myoferlin (Fer-1-like protein 3) Myof Fer1l3 Kiaa1207 Mus musculus (Mouse) 2048 cellular response to heat [GO:0034605]; plasma membrane repair [GO:0001778]; regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030947] GO:0001778; GO:0005543; GO:0005886; GO:0005901; GO:0016021; GO:0030659; GO:0030947; GO:0031410; GO:0031965; GO:0034605; GO:0043231; GO:0070062 0 0 0 PF00168;PF08165;PF08150;PF08151;PF16165; 4917 m.15277 1662807.6 680631.75 1432951.789 19454362.96 1054852 1221313.688 1282018.05 1178905.474 5345119.2 1171354.294 0.419948782 CHOYP_NRG.1.1 P20241 m.10622 sp NRG_DROME 33.938 1158 692 23 68 1197 26 1138 0 592 NRG_DROME reviewed Neuroglian Nrg CG1634 Drosophila melanogaster (Fruit fly) 1302 "axon ensheathment [GO:0008366]; axon extension [GO:0048675]; axonogenesis [GO:0007409]; cell adhesion involved in heart morphogenesis [GO:0061343]; central complex development [GO:0048036]; dendrite morphogenesis [GO:0048813]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of glial blood-brain barrier [GO:0060857]; female courtship behavior [GO:0008050]; imaginal disc morphogenesis [GO:0007560]; male courtship behavior [GO:0008049]; melanotic encapsulation of foreign target [GO:0035011]; motor neuron axon guidance [GO:0008045]; mushroom body development [GO:0016319]; nerve maturation [GO:0021682]; neuron cell-cell adhesion [GO:0007158]; neuron projection morphogenesis [GO:0048812]; photoreceptor cell axon guidance [GO:0072499]; regulation of female receptivity [GO:0045924]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]; synapse organization [GO:0050808]" GO:0005509; GO:0005886; GO:0005918; GO:0005919; GO:0005923; GO:0007158; GO:0007173; GO:0007409; GO:0007560; GO:0008045; GO:0008049; GO:0008050; GO:0008366; GO:0016021; GO:0016319; GO:0016328; GO:0019991; GO:0021682; GO:0030175; GO:0035011; GO:0035151; GO:0045924; GO:0048036; GO:0048675; GO:0048812; GO:0048813; GO:0050808; GO:0060857; GO:0061343; GO:0072499 0 0 0 PF13882;PF00041;PF07679;PF00047; 5126 m.10622 316394.6 1970509.1 464232.1538 1406724.444 251095 512733.5385 67416.66667 319820.1818 97310 800996.8667 0.407869242 CHOYP_NRX4.1.1 Q94887 m.8135 sp NRX4_DROME 37.366 1215 685 27 1 1188 119 1284 0 768 NRX4_DROME reviewed Neurexin-4 (Neurexin IV) Nrx-IV Nrx CG6827 Drosophila melanogaster (Fruit fly) 1284 "axon ensheathment [GO:0008366]; cell adhesion involved in heart morphogenesis [GO:0061343]; cell-cell junction organization [GO:0045216]; dorsal closure [GO:0007391]; establishment of glial blood-brain barrier [GO:0060857]; establishment or maintenance of cell polarity [GO:0007163]; heart process [GO:0003015]; nerve maturation [GO:0021682]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]; synaptic target recognition [GO:0008039]; synaptic vesicle docking [GO:0016081]; synaptic vesicle targeting [GO:0016080]; terminal button organization [GO:0072553]" GO:0003015; GO:0005886; GO:0005887; GO:0005918; GO:0005919; GO:0007163; GO:0007391; GO:0008039; GO:0008104; GO:0008366; GO:0016080; GO:0016081; GO:0019991; GO:0021682; GO:0035151; GO:0045216; GO:0048786; GO:0060857; GO:0061343; GO:0072553; GO:0097105 0 0 0 PF00008;PF00754;PF02210; 5132 m.8135 262728.5 104543 149883.5 903287.0556 178791.375 4054948.833 175623 420431.9 2334874 1362073.417 5.219970387 CHOYP_NUP205.1.1 Q92621 m.54932 sp NU205_HUMAN 43.508 2064 1071 32 7 2031 2 2009 0 1640 NU205_HUMAN reviewed Nuclear pore complex protein Nup205 (205 kDa nucleoporin) (Nucleoporin Nup205) NUP205 C7orf14 KIAA0225 Homo sapiens (Human) 2012 "gene silencing by RNA [GO:0031047]; intracellular transport of virus [GO:0075733]; mitotic nuclear envelope disassembly [GO:0007077]; mRNA export from nucleus [GO:0006406]; nuclear pore complex assembly [GO:0051292]; nucleocytoplasmic transport [GO:0006913]; protein import into nucleus, docking [GO:0000059]; protein sumoylation [GO:0016925]; regulation of cellular response to heat [GO:1900034]; regulation of glucose transport [GO:0010827]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083]" GO:0000059; GO:0005635; GO:0005643; GO:0005654; GO:0005737; GO:0006406; GO:0006409; GO:0006913; GO:0007077; GO:0010827; GO:0016020; GO:0016032; GO:0016925; GO:0017056; GO:0019083; GO:0031047; GO:0031965; GO:0034399; GO:0044611; GO:0051292; GO:0075733; GO:1900034 0 0 0 PF11894; 5148 m.54932 353923.5714 363059.2222 551696 2111785.714 706560.1667 369630.4286 453156.2857 445860.8333 1460931.25 305309.5 0.742566669 CHOYP_NUP214.1.3 P35658 m.16350 sp NU214_HUMAN 36.341 399 237 10 5 391 11 404 1.51E-79 297 NU214_HUMAN reviewed Nuclear pore complex protein Nup214 (214 kDa nucleoporin) (Nucleoporin Nup214) (Protein CAN) NUP214 CAIN CAN KIAA0023 Homo sapiens (Human) 2090 gene silencing by RNA [GO:0031047]; intracellular transport of virus [GO:0075733]; mitotic nuclear envelope disassembly [GO:0007077]; mRNA export from nucleus [GO:0006406]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein sumoylation [GO:0016925]; regulation of cell cycle [GO:0051726]; regulation of cellular response to heat [GO:1900034]; regulation of glucose transport [GO:0010827]; regulation of mRNA stability [GO:0043488]; RNA export from nucleus [GO:0006405]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083] GO:0005049; GO:0005634; GO:0005654; GO:0005829; GO:0005925; GO:0006405; GO:0006406; GO:0006409; GO:0006606; GO:0006611; GO:0007077; GO:0008139; GO:0010827; GO:0016032; GO:0016925; GO:0017056; GO:0019083; GO:0031047; GO:0043231; GO:0043488; GO:0051726; GO:0075733; GO:1900034; GO:1990876 0 0 0 0 5149 m.16350 107254 322602 85799 482667 1830664 NA 1332825.5 88856.5 13061212.25 316734.6667 6.539281617 CHOYP_NUP214.2.3 P35658 m.20892 sp NU214_HUMAN 36.341 399 237 10 5 391 11 404 1.11E-79 297 NU214_HUMAN reviewed Nuclear pore complex protein Nup214 (214 kDa nucleoporin) (Nucleoporin Nup214) (Protein CAN) NUP214 CAIN CAN KIAA0023 Homo sapiens (Human) 2090 gene silencing by RNA [GO:0031047]; intracellular transport of virus [GO:0075733]; mitotic nuclear envelope disassembly [GO:0007077]; mRNA export from nucleus [GO:0006406]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein sumoylation [GO:0016925]; regulation of cell cycle [GO:0051726]; regulation of cellular response to heat [GO:1900034]; regulation of glucose transport [GO:0010827]; regulation of mRNA stability [GO:0043488]; RNA export from nucleus [GO:0006405]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083] GO:0005049; GO:0005634; GO:0005654; GO:0005829; GO:0005925; GO:0006405; GO:0006406; GO:0006409; GO:0006606; GO:0006611; GO:0007077; GO:0008139; GO:0010827; GO:0016032; GO:0016925; GO:0017056; GO:0019083; GO:0031047; GO:0043231; GO:0043488; GO:0051726; GO:0075733; GO:1900034; GO:1990876 0 0 0 0 5150 m.20892 107254 322602 85799 482667 1830664 NA 1332825.5 88856.5 13061212.25 316734.6667 6.539281617 CHOYP_NUP214.3.3 P35658 m.52826 sp NU214_HUMAN 36.341 399 237 10 5 391 11 404 4.40E-80 299 NU214_HUMAN reviewed Nuclear pore complex protein Nup214 (214 kDa nucleoporin) (Nucleoporin Nup214) (Protein CAN) NUP214 CAIN CAN KIAA0023 Homo sapiens (Human) 2090 gene silencing by RNA [GO:0031047]; intracellular transport of virus [GO:0075733]; mitotic nuclear envelope disassembly [GO:0007077]; mRNA export from nucleus [GO:0006406]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein sumoylation [GO:0016925]; regulation of cell cycle [GO:0051726]; regulation of cellular response to heat [GO:1900034]; regulation of glucose transport [GO:0010827]; regulation of mRNA stability [GO:0043488]; RNA export from nucleus [GO:0006405]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083] GO:0005049; GO:0005634; GO:0005654; GO:0005829; GO:0005925; GO:0006405; GO:0006406; GO:0006409; GO:0006606; GO:0006611; GO:0007077; GO:0008139; GO:0010827; GO:0016032; GO:0016925; GO:0017056; GO:0019083; GO:0031047; GO:0043231; GO:0043488; GO:0051726; GO:0075733; GO:1900034; GO:1990876 0 0 0 0 5151 m.52826 107254 322602 85799 482667 1830664 NA 1332825.5 88856.5 13061212.25 316734.6667 6.539281617 CHOYP_NUP50.1.1 Q9UKX7 m.17104 sp NUP50_HUMAN 49.412 170 68 5 547 701 292 458 2.87E-37 149 NUP50_HUMAN reviewed Nuclear pore complex protein Nup50 (50 kDa nucleoporin) (Nuclear pore-associated protein 60 kDa-like) (Nucleoporin Nup50) NUP50 NPAP60L PRO1146 Homo sapiens (Human) 468 gene silencing by RNA [GO:0031047]; intracellular transport of virus [GO:0075733]; mitotic nuclear envelope disassembly [GO:0007077]; mRNA export from nucleus [GO:0006406]; protein import into nucleus [GO:0006606]; protein sumoylation [GO:0016925]; regulation of cellular response to heat [GO:1900034]; regulation of glucose transport [GO:0010827]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083] GO:0005643; GO:0005654; GO:0005737; GO:0006406; GO:0006409; GO:0006606; GO:0007077; GO:0008536; GO:0010827; GO:0016032; GO:0016925; GO:0019083; GO:0031047; GO:0031965; GO:0075733; GO:1900034 0 0 0 PF08911;PF00638; 5152 m.17104 649485 138317 44314 616941 506377 323415 243671 196660.6667 691174 265019.5 0.879569531 CHOYP_PHUM_PHUM477110.1.1 P20241 m.53813 sp NRG_DROME 26.998 463 285 22 24 458 26 463 1.29E-28 126 NRG_DROME reviewed Neuroglian Nrg CG1634 Drosophila melanogaster (Fruit fly) 1302 "axon ensheathment [GO:0008366]; axon extension [GO:0048675]; axonogenesis [GO:0007409]; cell adhesion involved in heart morphogenesis [GO:0061343]; central complex development [GO:0048036]; dendrite morphogenesis [GO:0048813]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of glial blood-brain barrier [GO:0060857]; female courtship behavior [GO:0008050]; imaginal disc morphogenesis [GO:0007560]; male courtship behavior [GO:0008049]; melanotic encapsulation of foreign target [GO:0035011]; motor neuron axon guidance [GO:0008045]; mushroom body development [GO:0016319]; nerve maturation [GO:0021682]; neuron cell-cell adhesion [GO:0007158]; neuron projection morphogenesis [GO:0048812]; photoreceptor cell axon guidance [GO:0072499]; regulation of female receptivity [GO:0045924]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]; synapse organization [GO:0050808]" GO:0005509; GO:0005886; GO:0005918; GO:0005919; GO:0005923; GO:0007158; GO:0007173; GO:0007409; GO:0007560; GO:0008045; GO:0008049; GO:0008050; GO:0008366; GO:0016021; GO:0016319; GO:0016328; GO:0019991; GO:0021682; GO:0030175; GO:0035011; GO:0035151; GO:0045924; GO:0048036; GO:0048675; GO:0048812; GO:0048813; GO:0050808; GO:0060857; GO:0061343; GO:0072499 0 0 0 PF13882;PF00041;PF07679;PF00047; 5317 m.53813 1261178.5 141253 297746 373911.5 168897 186623.6667 17150 201437 87109 49149.5 0.241405504 CHOYP_RFA1.1.1 P27694 m.16020 sp RFA1_HUMAN 50.698 645 269 9 6 638 5 612 0 643 RFA1_HUMAN reviewed "Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]" RPA1 REPA1 RPA70 Homo sapiens (Human) 616 "base-excision repair [GO:0006284]; DNA damage response, detection of DNA damage [GO:0042769]; DNA-dependent DNA replication [GO:0006261]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; G1/S transition of mitotic cell cycle [GO:0000082]; interstrand cross-link repair [GO:0036297]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; protein sumoylation [GO:0016925]; regulation of cellular response to heat [GO:1900034]; regulation of signal transduction by p53 class mediator [GO:1901796]; telomere maintenance [GO:0000723]; telomere maintenance via recombination [GO:0000722]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]" GO:0000082; GO:0000722; GO:0000723; GO:0000724; GO:0000784; GO:0003684; GO:0003697; GO:0005634; GO:0005654; GO:0005662; GO:0006260; GO:0006261; GO:0006281; GO:0006283; GO:0006284; GO:0006289; GO:0006293; GO:0006294; GO:0006295; GO:0006296; GO:0006297; GO:0006298; GO:0006310; GO:0016605; GO:0016925; GO:0019985; GO:0033683; GO:0036297; GO:0042276; GO:0042769; GO:0046872; GO:0070987; GO:1900034; GO:1901796 0 0 0 PF04057;PF08646;PF16900;PF01336; 5542 m.16020 475423 1157909.889 846594.5 572171.6 227798.1667 96202 95007.66667 405697 308595.2 1227220.6 0.650240653 CHOYP_RNP1B.1.1 P04792 m.59889 sp HSPB1_HUMAN 36.145 83 52 1 46 127 89 171 9.52E-09 54.7 HSPB1_HUMAN reviewed Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27) HSPB1 HSP27 HSP28 Homo sapiens (Human) 205 cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028 0 0 0 PF00011; 5723 m.59889 1996542 25739 171339.5 665833.5 17751 388418.5 80537.5 6428505 591267.3333 768276.25 2.869800582 CHOYP_RNP1B.1.1 P04792 m.59889 sp HSPB1_HUMAN 36.145 83 52 1 46 127 89 171 9.52E-09 54.7 HSPB1_HUMAN reviewed Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27) HSPB1 HSP27 HSP28 Homo sapiens (Human) 205 cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028 0 0 0 PF00011; 5724 m.59893 636340 340809.8333 7943169.909 362777.6667 568209 237382.25 5959749.143 1408708.4 1734680.25 4352681.556 1.389988397 CHOYP_RNP1B.1.1 P04792 m.59893 sp HSPB1_HUMAN 37.838 74 45 1 28 100 95 168 1.34E-11 61.2 HSPB1_HUMAN reviewed Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27) HSPB1 HSP27 HSP28 Homo sapiens (Human) 205 cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028 0 0 0 PF00011; 5723 m.59889 1996542 25739 171339.5 665833.5 17751 388418.5 80537.5 6428505 591267.3333 768276.25 2.869800582 CHOYP_RNP1B.1.1 P04792 m.59893 sp HSPB1_HUMAN 37.838 74 45 1 28 100 95 168 1.34E-11 61.2 HSPB1_HUMAN reviewed Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27) HSPB1 HSP27 HSP28 Homo sapiens (Human) 205 cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028 0 0 0 PF00011; 5724 m.59893 636340 340809.8333 7943169.909 362777.6667 568209 237382.25 5959749.143 1408708.4 1734680.25 4352681.556 1.389988397 CHOYP_RSMB.2.2 P04792 m.37626 sp HSPB1_HUMAN 38.667 75 43 2 161 233 95 168 3.82E-10 60.8 HSPB1_HUMAN reviewed Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27) HSPB1 HSP27 HSP28 Homo sapiens (Human) 205 cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028 0 0 0 PF00011; 5940 m.37626 651414.5556 337618.1 6317623.786 378199.4438 467184 338760.75 3826765.727 2681237.5 1244984.25 2706129.875 1.324561491 CHOYP_TPR.1.2 Q5EE04 m.29645 sp TPR_XENLA 41.818 165 71 9 81 239 1739 1884 6.14E-21 99 TPR_XENLA reviewed Nucleoprotein TPR (NPC-associated intranuclear protein) (Translocated promoter region and nuclear basket protein) (Fragment) tpr Xenopus laevis (African clawed frog) 1997 cell division [GO:0051301]; cellular response to heat [GO:0034605]; MAPK import into nucleus [GO:0000189]; mitotic nuclear division [GO:0007067]; mitotic spindle assembly checkpoint [GO:0007094]; mRNA export from nucleus in response to heat stress [GO:0031990]; negative regulation of RNA export from nucleus [GO:0046832]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of translational initiation [GO:0045947]; positive regulation of heterochromatin assembly [GO:0031453]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein import into nucleus [GO:0042307]; regulation of mitotic sister chromatid separation [GO:0010965]; regulation of mitotic spindle assembly [GO:1901673]; response to epidermal growth factor [GO:0070849]; RNA export from nucleus [GO:0006405]; RNA import into nucleus [GO:0006404] GO:0000122; GO:0000189; GO:0000776; GO:0003682; GO:0003729; GO:0005487; GO:0005643; GO:0005737; GO:0005868; GO:0006404; GO:0006405; GO:0007067; GO:0007094; GO:0010965; GO:0019898; GO:0031072; GO:0031453; GO:0031965; GO:0031990; GO:0034399; GO:0034605; GO:0042307; GO:0042405; GO:0042803; GO:0044615; GO:0045947; GO:0046827; GO:0046832; GO:0051019; GO:0051301; GO:0070849; GO:0072686; GO:0090267; GO:0090316; GO:1901673 0 0 0 PF07926; 6422 m.29645 571120 7985 1101542 537214 883690 765499 666702 398041 228610 1867341.333 1.26588063 CHOYP_TPR.2.2 F1MA98 m.46877 sp TPR_RAT 32.401 1824 1071 28 14 1803 5 1700 0 785 TPR_RAT reviewed Nucleoprotein TPR (Megator) (NPC-associated intranuclear protein) (Translocated promoter region protein) Tpr Rattus norvegicus (Rat) 2360 cell division [GO:0051301]; cellular response to heat [GO:0034605]; cellular response to interferon-alpha [GO:0035457]; MAPK import into nucleus [GO:0000189]; mitotic nuclear division [GO:0007067]; mitotic spindle assembly checkpoint [GO:0007094]; mRNA export from nucleus in response to heat stress [GO:0031990]; negative regulation of RNA export from nucleus [GO:0046832]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of translational initiation [GO:0045947]; nuclear pore organization [GO:0006999]; positive regulation of heterochromatin assembly [GO:0031453]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; regulation of mitotic sister chromatid separation [GO:0010965]; regulation of mitotic spindle assembly [GO:1901673]; response to epidermal growth factor [GO:0070849]; RNA export from nucleus [GO:0006405]; RNA import into nucleus [GO:0006404] GO:0000122; GO:0000189; GO:0000776; GO:0003682; GO:0003729; GO:0005487; GO:0005635; GO:0005643; GO:0005737; GO:0005868; GO:0006404; GO:0006405; GO:0006611; GO:0006999; GO:0007067; GO:0007094; GO:0010965; GO:0019898; GO:0031072; GO:0031453; GO:0031965; GO:0031990; GO:0034399; GO:0034605; GO:0035457; GO:0042307; GO:0042405; GO:0042803; GO:0044615; GO:0045947; GO:0046827; GO:0046832; GO:0051019; GO:0051301; GO:0070849; GO:0072686; GO:0090267; GO:0090316; GO:1901673 0 0 0 PF07926; 6423 m.46877 145863.5385 155709.3333 1741161.813 112858.2 387180.6923 208318.2 2040074.545 847849.8333 255535.5 426889.5294 1.486041715 CHOYP_TSP_09282.1.1 Q20363 m.18814 sp SIP1_CAEEL 31.169 77 53 0 45 121 49 125 3.06E-08 52.4 SIP1_CAEEL reviewed Stress-induced protein 1 sip-1 F43D9.4 Caenorhabditis elegans 159 determination of adult lifespan [GO:0008340]; embryo development ending in birth or egg hatching [GO:0009792]; multicellular organismal protein metabolic process [GO:0044268]; response to heat [GO:0009408] GO:0005829; GO:0008340; GO:0009408; GO:0009792; GO:0044268; GO:0051082 0 0 0 PF00011; 6490 m.18814 834225 134981 239963 348262.3334 65866 45306 178638 144086 135198 45359 0.337946098 CHOYP_YBOXH.4.4 Q13442 m.45830 sp HAP28_HUMAN 66.667 78 25 1 91 168 73 149 1.50E-25 100 HAP28_HUMAN reviewed 28 kDa heat- and acid-stable phosphoprotein (PDGF-associated protein) (PAP) (PDGFA-associated protein 1) (PAP1) PDAP1 HASPP28 Homo sapiens (Human) 181 cell proliferation [GO:0008283]; signal transduction [GO:0007165] GO:0007165; GO:0008283; GO:0044822 0 0 0 PF10252; 6665 m.45830 335920 70956.66667 527300.3 72946 83594.5 71560.5 658715.3333 366610 314786 1663998.6 2.819859888