CHOYP_14332.1.2	P62325	m.5644	sp	BTG1_MOUSE	47.205	161	80	2	1	156	11	171	2.18E-47	155	BTG1_MOUSE	reviewed	Protein BTG1 (B-cell translocation gene 1 protein)	Btg1	Mus musculus (Mouse)	171	negative regulation of cell proliferation [GO:0008285]; positive regulation of angiogenesis [GO:0045766]; positive regulation of catalytic activity [GO:0043085]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of fibroblast apoptotic process [GO:2000271]; positive regulation of myoblast differentiation [GO:0045663]; protein methylation [GO:0006479]; response to oxidative stress [GO:0006979]; response to peptide hormone [GO:0043434]; spermatogenesis [GO:0007283]	GO:0005634; GO:0005737; GO:0006479; GO:0006979; GO:0007283; GO:0008285; GO:0019899; GO:0043085; GO:0043434; GO:0045603; GO:0045663; GO:0045766; GO:2000271	0	0	0	PF07742;	1	m.5643	3293219.556	1726699.5	2716275.545	13976900.44	2243615.1	4909780.357	3073463.222	1943599.9	5308420.417	1708631.273	0.707271369
CHOYP_1433G.2.2	Q4R979	m.63451	sp	RBM4_MACFA	43.571	140	75	2	10	146	69	207	1.80E-33	127	RBM4_MACFA	reviewed	RNA-binding protein 4 (RNA-binding motif protein 4)	RBM4 QtsA-10585	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	364	"cap-independent translational initiation [GO:0002190]; cell differentiation [GO:0030154]; circadian regulation of translation [GO:0097167]; entrainment of circadian clock by photoperiod [GO:0043153]; IRES-dependent translational initiation [GO:0002192]; miRNA mediated inhibition of translation [GO:0035278]; mRNA processing [GO:0006397]; negative regulation of translation [GO:0017148]; negative regulation of translational initiation [GO:0045947]; negative regulation of translation in response to stress [GO:0032055]; positive regulation of muscle cell differentiation [GO:0051149]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of nucleocytoplasmic transport [GO:0046822]; response to arsenic-containing substance [GO:0046685]; RNA splicing [GO:0008380]; stress-activated MAPK cascade [GO:0051403]"	GO:0000166; GO:0000381; GO:0002190; GO:0002192; GO:0003723; GO:0003729; GO:0003730; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0006397; GO:0008270; GO:0008380; GO:0010494; GO:0016607; GO:0017148; GO:0030154; GO:0032055; GO:0035198; GO:0035278; GO:0036002; GO:0043153; GO:0045947; GO:0046685; GO:0046822; GO:0051149; GO:0051403; GO:0097157; GO:0097158; GO:0097167	0	0	0	PF00076;PF00098;	6	m.63450	10460977.8	7264823.438	5228882.182	11503021.89	5483118.813	7031340	10340272.32	9302575	27924467.09	12652430.6	1.683768087
CHOYP_1433G.2.2	Q4R979	m.63451	sp	RBM4_MACFA	43.571	140	75	2	10	146	69	207	1.80E-33	127	RBM4_MACFA	reviewed	RNA-binding protein 4 (RNA-binding motif protein 4)	RBM4 QtsA-10585	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	364	"cap-independent translational initiation [GO:0002190]; cell differentiation [GO:0030154]; circadian regulation of translation [GO:0097167]; entrainment of circadian clock by photoperiod [GO:0043153]; IRES-dependent translational initiation [GO:0002192]; miRNA mediated inhibition of translation [GO:0035278]; mRNA processing [GO:0006397]; negative regulation of translation [GO:0017148]; negative regulation of translational initiation [GO:0045947]; negative regulation of translation in response to stress [GO:0032055]; positive regulation of muscle cell differentiation [GO:0051149]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of nucleocytoplasmic transport [GO:0046822]; response to arsenic-containing substance [GO:0046685]; RNA splicing [GO:0008380]; stress-activated MAPK cascade [GO:0051403]"	GO:0000166; GO:0000381; GO:0002190; GO:0002192; GO:0003723; GO:0003729; GO:0003730; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0006397; GO:0008270; GO:0008380; GO:0010494; GO:0016607; GO:0017148; GO:0030154; GO:0032055; GO:0035198; GO:0035278; GO:0036002; GO:0043153; GO:0045947; GO:0046685; GO:0046822; GO:0051149; GO:0051403; GO:0097157; GO:0097158; GO:0097167	0	0	0	PF00076;PF00098;	7	m.63451	229456.5556	780323.1111	351988.2222	755481.9091	4747114	2972555	112558.8571	362153	3853072.929	878322	1.191466832
CHOYP_ABCA1.2.3	P41233	m.11687	sp	ABCA1_MOUSE	40	675	344	13	258	903	1180	1822	1.21E-130	437	ABCA1_MOUSE	reviewed	ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ABC-1) (ATP-binding cassette 1)	Abca1 Abc1	Mus musculus (Mouse)	2261	"cellular response to cholesterol [GO:0071397]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to retinoic acid [GO:0071300]; cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; endosomal transport [GO:0016197]; G-protein coupled receptor signaling pathway [GO:0007186]; high-density lipoprotein particle assembly [GO:0034380]; interleukin-1 beta secretion [GO:0050702]; intracellular cholesterol transport [GO:0032367]; lipoprotein biosynthetic process [GO:0042158]; lipoprotein metabolic process [GO:0042157]; lysosome organization [GO:0007040]; peptide secretion [GO:0002790]; phagocytosis, engulfment [GO:0006911]; phospholipid efflux [GO:0033700]; phospholipid homeostasis [GO:0055091]; phospholipid translocation [GO:0045332]; platelet dense granule organization [GO:0060155]; positive regulation of cAMP biosynthetic process [GO:0030819]; positive regulation of cholesterol efflux [GO:0010875]; protein lipidation [GO:0006497]; regulation of Cdc42 protein signal transduction [GO:0032489]; response to drug [GO:0042493]; response to laminar fluid shear stress [GO:0034616]; response to low-density lipoprotein particle [GO:0055098]; response to nutrient [GO:0007584]; reverse cholesterol transport [GO:0043691]"	GO:0002790; GO:0005102; GO:0005524; GO:0005548; GO:0005794; GO:0005886; GO:0005887; GO:0006497; GO:0006911; GO:0007040; GO:0007186; GO:0007584; GO:0008203; GO:0008509; GO:0009897; GO:0010875; GO:0016197; GO:0017127; GO:0019905; GO:0030139; GO:0030819; GO:0031267; GO:0032367; GO:0032489; GO:0033344; GO:0033700; GO:0034185; GO:0034186; GO:0034188; GO:0034364; GO:0034380; GO:0034616; GO:0042157; GO:0042158; GO:0042493; GO:0042626; GO:0042632; GO:0043231; GO:0043691; GO:0045121; GO:0045332; GO:0045335; GO:0048471; GO:0050702; GO:0051117; GO:0055091; GO:0055098; GO:0060155; GO:0071222; GO:0071300; GO:0071397	0	0	0	PF00005;	59	m.11687	135848.2857	5214020.5	320156	1375048.889	232384.7143	267251.5556	520005.75	1782210.364	1596007.75	748949.4167	0.675294117
CHOYP_ABCA4.1.1	P41233	m.31461	sp	ABCA1_MOUSE	32.825	2163	1250	37	3010	5009	104	2226	0	1177	ABCA1_MOUSE	reviewed	ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ABC-1) (ATP-binding cassette 1)	Abca1 Abc1	Mus musculus (Mouse)	2261	"cellular response to cholesterol [GO:0071397]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to retinoic acid [GO:0071300]; cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; endosomal transport [GO:0016197]; G-protein coupled receptor signaling pathway [GO:0007186]; high-density lipoprotein particle assembly [GO:0034380]; interleukin-1 beta secretion [GO:0050702]; intracellular cholesterol transport [GO:0032367]; lipoprotein biosynthetic process [GO:0042158]; lipoprotein metabolic process [GO:0042157]; lysosome organization [GO:0007040]; peptide secretion [GO:0002790]; phagocytosis, engulfment [GO:0006911]; phospholipid efflux [GO:0033700]; phospholipid homeostasis [GO:0055091]; phospholipid translocation [GO:0045332]; platelet dense granule organization [GO:0060155]; positive regulation of cAMP biosynthetic process [GO:0030819]; positive regulation of cholesterol efflux [GO:0010875]; protein lipidation [GO:0006497]; regulation of Cdc42 protein signal transduction [GO:0032489]; response to drug [GO:0042493]; response to laminar fluid shear stress [GO:0034616]; response to low-density lipoprotein particle [GO:0055098]; response to nutrient [GO:0007584]; reverse cholesterol transport [GO:0043691]"	GO:0002790; GO:0005102; GO:0005524; GO:0005548; GO:0005794; GO:0005886; GO:0005887; GO:0006497; GO:0006911; GO:0007040; GO:0007186; GO:0007584; GO:0008203; GO:0008509; GO:0009897; GO:0010875; GO:0016197; GO:0017127; GO:0019905; GO:0030139; GO:0030819; GO:0031267; GO:0032367; GO:0032489; GO:0033344; GO:0033700; GO:0034185; GO:0034186; GO:0034188; GO:0034364; GO:0034380; GO:0034616; GO:0042157; GO:0042158; GO:0042493; GO:0042626; GO:0042632; GO:0043231; GO:0043691; GO:0045121; GO:0045332; GO:0045335; GO:0048471; GO:0050702; GO:0051117; GO:0055091; GO:0055098; GO:0060155; GO:0071222; GO:0071300; GO:0071397	0	0	0	PF00005;	60	m.31461	3968504.5	5314696.333	NA	9778382.667	1903748	772444	5286648	17234	2466055	8248519	0.640711071
CHOYP_ACT.9.27	P62325	m.24631	sp	BTG1_MOUSE	47.205	161	80	2	1	156	11	171	2.18E-47	155	BTG1_MOUSE	reviewed	Protein BTG1 (B-cell translocation gene 1 protein)	Btg1	Mus musculus (Mouse)	171	negative regulation of cell proliferation [GO:0008285]; positive regulation of angiogenesis [GO:0045766]; positive regulation of catalytic activity [GO:0043085]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of fibroblast apoptotic process [GO:2000271]; positive regulation of myoblast differentiation [GO:0045663]; protein methylation [GO:0006479]; response to oxidative stress [GO:0006979]; response to peptide hormone [GO:0043434]; spermatogenesis [GO:0007283]	GO:0005634; GO:0005737; GO:0006479; GO:0006979; GO:0007283; GO:0008285; GO:0019899; GO:0043085; GO:0043434; GO:0045603; GO:0045663; GO:0045766; GO:2000271	0	0	0	PF07742;	131	m.24629	6945383.727	302723107.2	72394162.85	210980052.5	181571192.2	372065.8571	298992616.5	25577198.86	1416715827	1617153.444	2.250508111
CHOYP_ACT.9.27	P62325	m.24631	sp	BTG1_MOUSE	47.205	161	80	2	1	156	11	171	2.18E-47	155	BTG1_MOUSE	reviewed	Protein BTG1 (B-cell translocation gene 1 protein)	Btg1	Mus musculus (Mouse)	171	negative regulation of cell proliferation [GO:0008285]; positive regulation of angiogenesis [GO:0045766]; positive regulation of catalytic activity [GO:0043085]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of fibroblast apoptotic process [GO:2000271]; positive regulation of myoblast differentiation [GO:0045663]; protein methylation [GO:0006479]; response to oxidative stress [GO:0006979]; response to peptide hormone [GO:0043434]; spermatogenesis [GO:0007283]	GO:0005634; GO:0005737; GO:0006479; GO:0006979; GO:0007283; GO:0008285; GO:0019899; GO:0043085; GO:0043434; GO:0045603; GO:0045663; GO:0045766; GO:2000271	0	0	0	PF07742;	132	m.24630	1220132	180739.9231	1041195.892	383632.1667	641262.9	740840.3636	378081.2308	562590.6222	358103.0769	2347862.5	1.265510461
CHOYP_AGAP_AGAP002686.1.1	Q8BRK8	m.5987	sp	AAPK2_MOUSE	52.885	104	47	1	1	102	244	347	2.51E-32	121	AAPK2_MOUSE	reviewed	5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK subunit alpha-2) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31)	Prkaa2	Mus musculus (Mouse)	552	"autophagy [GO:0006914]; cellular response to drug [GO:0035690]; cellular response to glucose starvation [GO:0042149]; cellular response to nutrient levels [GO:0031669]; cellular response to prostaglandin E stimulus [GO:0071380]; cholesterol biosynthetic process [GO:0006695]; fatty acid biosynthetic process [GO:0006633]; fatty acid homeostasis [GO:0055089]; glucose homeostasis [GO:0042593]; lipid biosynthetic process [GO:0008610]; membrane organization [GO:0061024]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of TOR signaling [GO:0032007]; positive regulation of autophagy [GO:0010508]; positive regulation of glycolytic process [GO:0045821]; protein phosphorylation [GO:0006468]; regulation of circadian rhythm [GO:0042752]; regulation of energy homeostasis [GO:2000505]; regulation of gene expression [GO:0010468]; regulation of macroautophagy [GO:0016241]; regulation of transcription, DNA-templated [GO:0006355]; response to muscle activity [GO:0014850]; response to stress [GO:0006950]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]; Wnt signaling pathway [GO:0016055]"	GO:0003682; GO:0004674; GO:0004679; GO:0004712; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006351; GO:0006355; GO:0006468; GO:0006633; GO:0006695; GO:0006914; GO:0006950; GO:0007005; GO:0008610; GO:0010468; GO:0010508; GO:0014850; GO:0016055; GO:0016241; GO:0031588; GO:0031669; GO:0032007; GO:0035174; GO:0035690; GO:0042149; GO:0042593; GO:0042752; GO:0043066; GO:0045821; GO:0046872; GO:0047322; GO:0048511; GO:0050405; GO:0055089; GO:0061024; GO:0071380; GO:2000505	0	0	0	PF16579;PF00069;	196	m.5987	48482	264022	174027.6667	186049	523740.75	914188.5	122785.5	93425	6666217	191879.5	6.677549518
CHOYP_AIFM1.1.1	O95831	m.1582	sp	AIFM1_HUMAN	47.135	541	262	8	70	601	83	608	1.24E-157	468	AIFM1_HUMAN	reviewed	"Apoptosis-inducing factor 1, mitochondrial (EC 1.1.1.-) (Programmed cell death protein 8)"	AIFM1 AIF PDCD8	Homo sapiens (Human)	613	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cell redox homeostasis [GO:0045454]; cellular response to aldosterone [GO:1904045]; cellular response to estradiol stimulus [GO:0071392]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to nitric oxide [GO:0071732]; cellular response to oxygen-glucose deprivation [GO:0090650]; chromosome condensation [GO:0030261]; DNA catabolic process [GO:0006308]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; mitochondrial respiratory chain complex I assembly [GO:0032981]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; positive regulation of apoptotic process [GO:0043065]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of apoptotic DNA fragmentation [GO:1902510]; response to ischemia [GO:0002931]; response to L-glutamate [GO:1902065]; response to toxic substance [GO:0009636]	GO:0002931; GO:0003677; GO:0005634; GO:0005739; GO:0005743; GO:0005758; GO:0005829; GO:0006308; GO:0006915; GO:0006919; GO:0009055; GO:0009636; GO:0016174; GO:0016651; GO:0030182; GO:0030261; GO:0032981; GO:0043065; GO:0043525; GO:0045454; GO:0048471; GO:0051402; GO:0070059; GO:0070301; GO:0071392; GO:0071732; GO:0071949; GO:0090650; GO:1902065; GO:1902510; GO:1904045	0	0	0	PF14721;PF07992;	222	m.1582	973976.6	84310	1359083.667	479589.75	315224.8	3251126.5	300368	479530.6	1802073.6	1379353.222	2.245341515
CHOYP_AKT1.1.2	Q8INB9	m.23291	sp	AKT1_DROME	81.224	245	46	0	1	245	323	567	5.96E-151	437	AKT1_DROME	reviewed	RAC serine/threonine-protein kinase (DAkt) (DRAC-PK) (Dakt1) (EC 2.7.11.1) (Akt) (Protein kinase B) (PKB)	Akt1 CG4006	Drosophila melanogaster (Fruit fly)	611	"apoptotic process [GO:0006915]; chitin-based embryonic cuticle biosynthetic process [GO:0008362]; circadian rhythm [GO:0007623]; dendrite regeneration [GO:0031104]; epithelial cell migration, open tracheal system [GO:0007427]; insulin receptor signaling pathway [GO:0008286]; intracellular signal transduction [GO:0035556]; lipid metabolic process [GO:0006629]; lipid storage [GO:0019915]; long term synaptic depression [GO:0060292]; multicellular organism growth [GO:0035264]; myoblast fusion [GO:0007520]; negative regulation of apoptotic process [GO:0043066]; negative regulation of neuron death [GO:1901215]; negative regulation of peptide hormone secretion [GO:0090278]; negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of axon regeneration [GO:0048680]; positive regulation of cell growth [GO:0030307]; positive regulation of cell size [GO:0045793]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of organ growth [GO:0046622]; protein phosphorylation [GO:0006468]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of dendrite development [GO:0050773]; regulation of glucose metabolic process [GO:0010906]; regulation of hemocyte proliferation [GO:0035206]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein import into nucleus [GO:0042306]; response to oxidative stress [GO:0006979]; somatic muscle development [GO:0007525]"	GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006468; GO:0006629; GO:0006915; GO:0006979; GO:0007424; GO:0007427; GO:0007520; GO:0007525; GO:0007623; GO:0008286; GO:0008360; GO:0008361; GO:0008362; GO:0009986; GO:0010906; GO:0018105; GO:0019915; GO:0030307; GO:0031104; GO:0035091; GO:0035206; GO:0035264; GO:0035556; GO:0040014; GO:0040018; GO:0042306; GO:0043025; GO:0043066; GO:0045793; GO:0045886; GO:0046620; GO:0046622; GO:0048477; GO:0048680; GO:0050773; GO:0060292; GO:0090278; GO:1901215	0	0	0	PF00169;PF00069;PF00433;	228	m.23291	101574	NA	42517	131933	83082	101967	113421	56333	337843.5	194345	1.790912989
CHOYP_AKT1.2.2	Q8INB9	m.51125	sp	AKT1_DROME	63.2	500	139	5	10	474	107	596	0	639	AKT1_DROME	reviewed	RAC serine/threonine-protein kinase (DAkt) (DRAC-PK) (Dakt1) (EC 2.7.11.1) (Akt) (Protein kinase B) (PKB)	Akt1 CG4006	Drosophila melanogaster (Fruit fly)	611	"apoptotic process [GO:0006915]; chitin-based embryonic cuticle biosynthetic process [GO:0008362]; circadian rhythm [GO:0007623]; dendrite regeneration [GO:0031104]; epithelial cell migration, open tracheal system [GO:0007427]; insulin receptor signaling pathway [GO:0008286]; intracellular signal transduction [GO:0035556]; lipid metabolic process [GO:0006629]; lipid storage [GO:0019915]; long term synaptic depression [GO:0060292]; multicellular organism growth [GO:0035264]; myoblast fusion [GO:0007520]; negative regulation of apoptotic process [GO:0043066]; negative regulation of neuron death [GO:1901215]; negative regulation of peptide hormone secretion [GO:0090278]; negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of axon regeneration [GO:0048680]; positive regulation of cell growth [GO:0030307]; positive regulation of cell size [GO:0045793]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of organ growth [GO:0046622]; protein phosphorylation [GO:0006468]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of dendrite development [GO:0050773]; regulation of glucose metabolic process [GO:0010906]; regulation of hemocyte proliferation [GO:0035206]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein import into nucleus [GO:0042306]; response to oxidative stress [GO:0006979]; somatic muscle development [GO:0007525]"	GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006468; GO:0006629; GO:0006915; GO:0006979; GO:0007424; GO:0007427; GO:0007520; GO:0007525; GO:0007623; GO:0008286; GO:0008360; GO:0008361; GO:0008362; GO:0009986; GO:0010906; GO:0018105; GO:0019915; GO:0030307; GO:0031104; GO:0035091; GO:0035206; GO:0035264; GO:0035556; GO:0040014; GO:0040018; GO:0042306; GO:0043025; GO:0043066; GO:0045793; GO:0045886; GO:0046620; GO:0046622; GO:0048477; GO:0048680; GO:0050773; GO:0060292; GO:0090278; GO:1901215	0	0	0	PF00169;PF00069;PF00433;	229	m.51125	101574	NA	42517	131933	83082	101967	113421	56333	337843.5	194345	1.790912989
CHOYP_ANXA4.2.2	P20072	m.57444	sp	ANXA7_BOVIN	62.416	149	56	0	4	152	153	301	1.33E-60	197	ANXA7_BOVIN	reviewed	Annexin A7 (Annexin VII) (Annexin-7) (Synexin)	ANXA7 ANX7	Bos taurus (Bovine)	463	autophagy [GO:0006914]; cell proliferation [GO:0008283]; cellular calcium ion homeostasis [GO:0006874]; cellular water homeostasis [GO:0009992]; epithelial cell differentiation [GO:0030855]; hemostasis [GO:0007599]; negative regulation of gene expression [GO:0010629]; regulation of cell shape [GO:0008360]; response to salt stress [GO:0009651]; social behavior [GO:0035176]	GO:0005509; GO:0005544; GO:0005635; GO:0005789; GO:0005829; GO:0005886; GO:0006874; GO:0006914; GO:0007599; GO:0008283; GO:0008360; GO:0009651; GO:0009992; GO:0010629; GO:0030855; GO:0035176; GO:0042584; GO:0042802; GO:0044822; GO:0048306; GO:0070062	0	0	0	PF00191;	267	m.57444	42641.5	126873	867329	84070.2	62815.25	599296.25	588864.5	578690.5	2222453.667	431413.8333	3.734570106
CHOYP_ANXA7.2.4	P20073	m.30574	sp	ANXA7_HUMAN	44.818	357	163	3	219	575	166	488	7.09E-93	296	ANXA7_HUMAN	reviewed	Annexin A7 (Annexin VII) (Annexin-7) (Synexin)	ANXA7 ANX7 SNX OK/SW-cl.95	Homo sapiens (Human)	488	autophagy [GO:0006914]; cell proliferation [GO:0008283]; cellular calcium ion homeostasis [GO:0006874]; cellular water homeostasis [GO:0009992]; epithelial cell differentiation [GO:0030855]; hemostasis [GO:0007599]; membrane fusion [GO:0061025]; negative regulation of gene expression [GO:0010629]; regulation of cell shape [GO:0008360]; response to calcium ion [GO:0051592]; response to organic cyclic compound [GO:0014070]; response to salt stress [GO:0009651]; social behavior [GO:0035176]	GO:0005178; GO:0005509; GO:0005544; GO:0005634; GO:0005635; GO:0005789; GO:0005829; GO:0005886; GO:0006874; GO:0006914; GO:0007599; GO:0008283; GO:0008360; GO:0009651; GO:0009992; GO:0010629; GO:0014070; GO:0016020; GO:0030855; GO:0035176; GO:0044822; GO:0048306; GO:0051592; GO:0061025; GO:0070062	0	0	0	PF00191;	268	m.30575	2035689.6	575917.3333	1564865.8	3338535.5	940249	523724.75	2367120	137041	5420484.8	1006087.8	1.118175129
CHOYP_BAG3.1.1	O95429	m.15160	sp	BAG4_HUMAN	38.776	98	56	1	344	437	360	457	3.30E-15	81.3	BAG4_HUMAN	reviewed	BAG family molecular chaperone regulator 4 (BAG-4) (Bcl-2-associated athanogene 4) (Silencer of death domains)	BAG4 SODD	Homo sapiens (Human)	457	"cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to tumor necrosis factor [GO:0071356]; negative regulation of apoptotic process [GO:0043066]; negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity [GO:2001145]; negative regulation of protein targeting to mitochondrion [GO:1903215]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell adhesion [GO:0045785]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of stress fiber assembly [GO:0051496]; protein folding [GO:0006457]; protein localization to plasma membrane [GO:0072659]; regulation of cellular response to heat [GO:1900034]; ruffle assembly [GO:0097178]; tumor necrosis factor-mediated signaling pathway [GO:0033209]"	GO:0000774; GO:0005057; GO:0005634; GO:0005829; GO:0005886; GO:0006457; GO:0010763; GO:0030838; GO:0031625; GO:0033138; GO:0033209; GO:0043066; GO:0044822; GO:0045785; GO:0051496; GO:0051897; GO:0071356; GO:0071364; GO:0072659; GO:0097178; GO:1900034; GO:1903215; GO:2001145	0	0	0	PF02179;	333	m.15160	522634	66919.5	60152	1074832.5	44503	2129184	527999	60445	170897	44323	1.657874521
CHOYP_BICD2.1.1	Q8BR07	m.9177	sp	BICD1_MOUSE	42.705	843	412	13	10	799	9	833	0	547	BICD1_MOUSE	reviewed	Protein bicaudal D homolog 1 (Bic-D 1)	Bicd1	Mus musculus (Mouse)	835	microtubule anchoring at microtubule organizing center [GO:0072393]; minus-end-directed organelle transport along microtubule [GO:0072385]; negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway [GO:1900737]; negative regulation of phospholipase C activity [GO:1900275]; positive regulation of receptor-mediated endocytosis [GO:0048260]; protein localization to organelle [GO:0033365]; regulation of proteinase activated receptor activity [GO:1900276]; stress granule assembly [GO:0034063]; viral process [GO:0016032]	GO:0005794; GO:0005802; GO:0005829; GO:0005881; GO:0008093; GO:0016020; GO:0016032; GO:0017137; GO:0031410; GO:0031871; GO:0033365; GO:0034063; GO:0034452; GO:0045502; GO:0048260; GO:0048471; GO:0072385; GO:0072393; GO:0072517; GO:1900275; GO:1900276; GO:1900737	0	0	0	PF09730;	348	m.9177	181242	23653	2663627	710199.3333	45206	NA	55396	237097.5	668633	970758.3333	0.666364366
CHOYP_BIG3.1.1	Q9Z2W1	m.51448	sp	STK25_MOUSE	78.618	304	63	2	9	310	13	316	1.42E-162	472	STK25_MOUSE	reviewed	Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response kinase 1) (SOK-1) (Ste20/oxidant stress response kinase 1)	Stk25 Sok1	Mus musculus (Mouse)	426	establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Golgi localization [GO:0051645]; Golgi reassembly [GO:0090168]; intrinsic apoptotic signaling pathway in response to hydrogen peroxide [GO:0036481]; positive regulation of axonogenesis [GO:0050772]; positive regulation of stress-activated MAPK cascade [GO:0032874]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; response to hydrogen peroxide [GO:0042542]	GO:0000139; GO:0004702; GO:0005524; GO:0005737; GO:0006468; GO:0007163; GO:0032874; GO:0036481; GO:0042542; GO:0042803; GO:0046777; GO:0046872; GO:0050772; GO:0051645; GO:0051683; GO:0070062; GO:0090168	0	0	0	PF00069;	352	m.51448	246911.5	2041324	855477.3333	46377.5	2257489.75	1435030.5	825556.6667	121255.3333	287718	153497.75	0.518222441
CHOYP_BRAFLDRAFT_113892.1.1	P48508	m.44055	sp	GSH0_RAT	37.5	256	159	1	12	266	16	271	5.47E-65	207	GSH0_RAT	reviewed	Glutamate--cysteine ligase regulatory subunit (GCS light chain) (Gamma-ECS regulatory subunit) (Gamma-glutamylcysteine synthetase regulatory subunit) (Glutamate--cysteine ligase modifier subunit)	Gclm Glclr	Rattus norvegicus (Rat)	274	aging [GO:0007568]; apoptotic mitochondrial changes [GO:0008637]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to glucose stimulus [GO:0071333]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to thyroxine stimulus [GO:0097069]; cysteine metabolic process [GO:0006534]; glutamate metabolic process [GO:0006536]; glutathione biosynthetic process [GO:0006750]; hepatic stellate cell activation [GO:0035733]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of glutamate-cysteine ligase activity [GO:0035229]; regulation of blood vessel size [GO:0050880]; regulation of mitochondrial depolarization [GO:0051900]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to human chorionic gonadotropin [GO:0044752]; response to nitrosative stress [GO:0051409]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]	GO:0004357; GO:0006534; GO:0006536; GO:0006750; GO:0006979; GO:0007568; GO:0007584; GO:0008637; GO:0014823; GO:0017109; GO:0030234; GO:0035226; GO:0035229; GO:0035729; GO:0035733; GO:0042493; GO:0043524; GO:0044344; GO:0044752; GO:0046982; GO:0050880; GO:0051409; GO:0051900; GO:0071333; GO:0071372; GO:0097069; GO:2001237	PATHWAY: Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 1/2.	0	0	PF00248;	394	m.44055	81002	124806	256648	185693.25	75789.66667	67788.5	101137	52280	471324	104628.3333	1.101139633
CHOYP_BRAFLDRAFT_119799.1.1	P30044	m.23765	sp	PRDX5_HUMAN	59.524	168	66	1	18	183	43	210	7.18E-69	211	PRDX5_HUMAN	reviewed	"Peroxiredoxin-5, mitochondrial (EC 1.11.1.15) (Alu corepressor 1) (Antioxidant enzyme B166) (AOEB166) (Liver tissue 2D-page spot 71B) (PLP) (Peroxiredoxin V) (Prx-V) (Peroxisomal antioxidant enzyme) (TPx type VI) (Thioredoxin peroxidase PMP20) (Thioredoxin reductase)"	PRDX5 ACR1 SBBI10	Homo sapiens (Human)	214	cell redox homeostasis [GO:0045454]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; inflammatory response [GO:0006954]; NADPH oxidation [GO:0070995]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of transcription from RNA polymerase III promoter [GO:0016480]; positive regulation of collagen biosynthetic process [GO:0032967]; reactive nitrogen species metabolic process [GO:2001057]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; response to oxidative stress [GO:0006979]; response to reactive oxygen species [GO:0000302]	GO:0000302; GO:0001016; GO:0004601; GO:0005102; GO:0005615; GO:0005634; GO:0005737; GO:0005739; GO:0005759; GO:0005777; GO:0005782; GO:0005829; GO:0006954; GO:0006979; GO:0008379; GO:0016209; GO:0016480; GO:0031410; GO:0032967; GO:0034614; GO:0042744; GO:0043027; GO:0043066; GO:0043231; GO:0045454; GO:0046983; GO:0048471; GO:0051354; GO:0051920; GO:0060785; GO:0070062; GO:0070995; GO:0072541; GO:2001057	0	0	0	PF08534;	478	m.23765	23982944.17	13890076.81	4635772	2601289.75	17147594.83	1161584.636	5768779.182	967580.7	5408679.8	31874359.25	0.725709428
CHOYP_BRAFLDRAFT_203655.1.2	P09874	m.12	sp	PARP1_HUMAN	42.609	115	60	2	1	114	696	805	3.08E-23	96.3	PARP1_HUMAN	reviewed	Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 1) (ARTD1) (NAD(+) ADP-ribosyltransferase 1) (ADPRT 1) (Poly[ADP-ribose] synthase 1)	PARP1 ADPRT PPOL	Homo sapiens (Human)	1014	"ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; DNA damage response, detection of DNA damage [GO:0042769]; DNA ligation involved in DNA repair [GO:0051103]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; lagging strand elongation [GO:0006273]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of SMAD protein import into nucleus [GO:0060391]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; protein sumoylation [GO:0016925]; regulation of cellular protein localization [GO:1903827]; signal transduction involved in regulation of gene expression [GO:0023019]; transcription from RNA polymerase II promoter [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]"	GO:0000122; GO:0000715; GO:0000717; GO:0000724; GO:0000784; GO:0003677; GO:0003910; GO:0003950; GO:0005634; GO:0005635; GO:0005654; GO:0005667; GO:0005730; GO:0005739; GO:0006273; GO:0006281; GO:0006293; GO:0006294; GO:0006295; GO:0006296; GO:0006302; GO:0006366; GO:0006471; GO:0006974; GO:0007005; GO:0007179; GO:0008134; GO:0008270; GO:0010613; GO:0016020; GO:0016540; GO:0016925; GO:0019899; GO:0019901; GO:0023019; GO:0030225; GO:0032042; GO:0032869; GO:0033683; GO:0034599; GO:0036211; GO:0042769; GO:0042802; GO:0043234; GO:0043504; GO:0044822; GO:0045944; GO:0047485; GO:0051103; GO:0051287; GO:0060391; GO:0070212; GO:0070911; GO:1903827; GO:1904357; GO:1990966; GO:2000679	0	0	0	PF00533;PF08063;PF00644;PF02877;PF05406;PF00645;	623	m.12	68866	17367	17733	124245.5	212698.5	229406.6667	17093	57229	76547.66667	73861.33333	1.030000832
CHOYP_BRAFLDRAFT_207882.1.1	Q5I0H9	m.352	sp	PDIA5_RAT	43.791	153	80	2	1	147	29	181	8.37E-39	140	PDIA5_RAT	reviewed	Protein disulfide-isomerase A5 (EC 5.3.4.1)	Pdia5	Rattus norvegicus (Rat)	517	cell redox homeostasis [GO:0045454]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976]	GO:0003756; GO:0005783; GO:0005788; GO:0006457; GO:0034976; GO:0045454	0	0	0	PF00085;	640	m.351	113728	195140.3333	1154887.667	699588.6	640335.6667	2456147.25	815110	518133	1384955.5	1371290.25	2.334658512
CHOYP_BRAFLDRAFT_207882.1.1	Q921X9	m.351	sp	PDIA5_MOUSE	44.318	176	92	3	1	172	186	359	1.89E-46	161	PDIA5_MOUSE	reviewed	Protein disulfide-isomerase A5 (EC 5.3.4.1) (Protein disulfide isomerase-related protein)	Pdia5 Pdir	Mus musculus (Mouse)	517	cell redox homeostasis [GO:0045454]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976]	GO:0003756; GO:0005783; GO:0005788; GO:0006457; GO:0034976; GO:0045454	0	0	0	PF00085;	640	m.351	113728	195140.3333	1154887.667	699588.6	640335.6667	2456147.25	815110	518133	1384955.5	1371290.25	2.334658512
CHOYP_BRAFLDRAFT_223429.1.2	Q13148	m.30136	sp	TADBP_HUMAN	62.909	275	97	4	36	308	1	272	6.33E-125	371	TADBP_HUMAN	reviewed	TAR DNA-binding protein 43 (TDP-43)	TARDBP TDP43	Homo sapiens (Human)	414	3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA processing [GO:0006397]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of gene expression [GO:0010629]; negative regulation of protein phosphorylation [GO:0001933]; nuclear fragmentation involved in apoptotic nuclear change [GO:0030264]; nuclear inner membrane organization [GO:0071765]; positive regulation of insulin secretion [GO:0032024]; regulation of cell cycle [GO:0051726]; response to endoplasmic reticulum stress [GO:0034976]; RNA splicing [GO:0008380]; transcription from RNA polymerase II promoter [GO:0006366]	GO:0000166; GO:0001205; GO:0001933; GO:0003690; GO:0003700; GO:0003723; GO:0003730; GO:0005634; GO:0005654; GO:0005726; GO:0005737; GO:0006366; GO:0006397; GO:0008380; GO:0010629; GO:0016607; GO:0030264; GO:0032024; GO:0034976; GO:0035061; GO:0042802; GO:0043922; GO:0044822; GO:0051726; GO:0070935; GO:0071765	0	0	0	PF00076;	672	m.30136	1980955.333	64965	74817	34245	1901338	25552	2688211.5	52265	853096	4837339.75	2.084762434
CHOYP_BRAFLDRAFT_61845.1.1	P56597	m.37831	sp	NDK5_HUMAN	67.839	199	64	0	17	215	4	202	3.66E-107	310	NDK5_HUMAN	reviewed	Nucleoside diphosphate kinase homolog 5 (NDK-H 5) (NDP kinase homolog 5) (Inhibitor of p53-induced apoptosis-beta) (IPIA-beta) (Testis-specific nm23 homolog) (nm23-H5)	NME5	Homo sapiens (Human)	212	cilium assembly [GO:0042384]; CTP biosynthetic process [GO:0006241]; epithelial cilium movement [GO:0003351]; GTP biosynthetic process [GO:0006183]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; nucleoside metabolic process [GO:0009116]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]; UTP biosynthetic process [GO:0006228]; ventricular system development [GO:0021591]	GO:0003351; GO:0004550; GO:0005622; GO:0006183; GO:0006228; GO:0006241; GO:0007283; GO:0007286; GO:0009116; GO:0021591; GO:0036126; GO:0042384; GO:1902176	0	0	0	PF05186;PF00334;	852	m.37831	288598.5	29334	192991	650690	71418	159705	153020	1577694	598702	3769738.143	5.075992903
CHOYP_BRAFLDRAFT_83361.1.1	Q8C7Q4	m.59005	sp	RBM4_MOUSE	46.212	132	67	2	41	169	77	207	3.93E-33	127	RBM4_MOUSE	reviewed	RNA-binding protein 4 (Lark homolog) (mLark) (RNA-binding motif protein 4) (RNA-binding motif protein 4a)	Rbm4 Rbm4a	Mus musculus (Mouse)	361	"cap-independent translational initiation [GO:0002190]; circadian regulation of gene expression [GO:0032922]; circadian regulation of translation [GO:0097167]; enteroendocrine cell differentiation [GO:0035883]; entrainment of circadian clock by photoperiod [GO:0043153]; glucose homeostasis [GO:0042593]; insulin secretion involved in cellular response to glucose stimulus [GO:0035773]; IRES-dependent translational initiation [GO:0002192]; miRNA mediated inhibition of translation [GO:0035278]; mRNA processing [GO:0006397]; negative regulation of translation [GO:0017148]; negative regulation of translational initiation [GO:0045947]; negative regulation of translation in response to stress [GO:0032055]; pancreas development [GO:0031016]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of translation [GO:0045727]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of gene expression [GO:0010468]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of nucleocytoplasmic transport [GO:0046822]; response to arsenic-containing substance [GO:0046685]; RNA splicing [GO:0008380]; stress-activated MAPK cascade [GO:0051403]"	GO:0000166; GO:0000381; GO:0002190; GO:0002192; GO:0003723; GO:0003729; GO:0003730; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0006397; GO:0008270; GO:0008380; GO:0010468; GO:0010494; GO:0016607; GO:0017148; GO:0031016; GO:0032055; GO:0032922; GO:0035198; GO:0035278; GO:0035773; GO:0035883; GO:0036002; GO:0042593; GO:0043153; GO:0044822; GO:0045727; GO:0045947; GO:0046626; GO:0046685; GO:0046822; GO:0048471; GO:0051149; GO:0051403; GO:0097157; GO:0097158; GO:0097167	0	0	0	PF00076;PF00098;	964	m.59005	229456.5556	780323.1111	351988.2222	755481.9091	4747114	2972555	112558.8571	362153	3853072.929	878322	1.191466832
CHOYP_BRAFLDRAFT_90929.1.1	Q14831	m.54455	sp	GRM7_HUMAN	27.789	475	300	13	538	988	46	501	2.19E-46	184	GRM7_HUMAN	reviewed	Metabotropic glutamate receptor 7 (mGluR7)	GRM7 GPRC1G MGLUR7	Homo sapiens (Human)	915	"adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway [GO:0007196]; adult behavior [GO:0030534]; chemical synaptic transmission [GO:0007268]; conditioned taste aversion [GO:0001661]; multicellular organismal response to stress [GO:0033555]; negative regulation of adenylate cyclase activity [GO:0007194]; negative regulation of cAMP biosynthetic process [GO:0030818]; negative regulation of glutamate secretion [GO:0014050]; regulation of synaptic transmission, glutamatergic [GO:0051966]; sensory perception of smell [GO:0007608]; sensory perception of sound [GO:0007605]; short-term memory [GO:0007614]; transmission of nerve impulse [GO:0019226]"	GO:0001642; GO:0001661; GO:0005245; GO:0005246; GO:0005509; GO:0005886; GO:0005887; GO:0005938; GO:0007194; GO:0007196; GO:0007268; GO:0007605; GO:0007608; GO:0007614; GO:0008066; GO:0010855; GO:0014050; GO:0016021; GO:0016595; GO:0019226; GO:0030165; GO:0030424; GO:0030425; GO:0030534; GO:0030818; GO:0032279; GO:0033555; GO:0042734; GO:0043198; GO:0043235; GO:0045211; GO:0048786; GO:0051966; GO:0070905	0	0	0	PF00003;PF01094;PF07562;	1032	m.54454	93479	30483	43294	74151	132143	217504	35097	1817412.333	20942003.5	1019406.5	64.33254807
CHOYP_BRAFLDRAFT_99019.8.8	Q07352	m.62208	sp	TISB_HUMAN	78.125	96	20	1	65	159	88	183	1.57E-47	167	TISB_HUMAN	reviewed	"Zinc finger protein 36, C3H1 type-like 1 (Butyrate response factor 1) (EGF-response factor 1) (ERF-1) (Protein TIS11B)"	ZFP36L1 BERG36 BRF1 ERF1 RNF162B TIS11B	Homo sapiens (Human)	338	"3'-UTR-mediated mRNA destabilization [GO:0061158]; apoptotic process [GO:0006915]; cell proliferation [GO:0008283]; cellular response to cAMP [GO:0071320]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to phorbol 13-acetate 12-myristate [GO:1904628]; cellular response to raffinose [GO:0097403]; cellular response to salt stress [GO:0071472]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cellular response to tumor necrosis factor [GO:0071356]; chorio-allantoic fusion [GO:0060710]; ERK1 and ERK2 cascade [GO:0070371]; heart development [GO:0007507]; MAPK cascade [GO:0000165]; mesendoderm development [GO:0048382]; mRNA transport [GO:0051028]; multicellular organism growth [GO:0035264]; negative regulation of erythrocyte differentiation [GO:0045647]; neural tube development [GO:0021915]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; nuclear-transcribed mRNA catabolic process, deadenylation-independent decay [GO:0031086]; p38MAPK cascade [GO:0038066]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of intracellular mRNA localization [GO:1904582]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; proepicardium development [GO:0003342]; protein kinase B signaling [GO:0043491]; regulation of gene expression [GO:0010468]; regulation of keratinocyte apoptotic process [GO:1902172]; regulation of keratinocyte differentiation [GO:0045616]; regulation of keratinocyte proliferation [GO:0010837]; regulation of mRNA 3'-end processing [GO:0031440]; regulation of mRNA stability [GO:0043488]; regulation of myoblast differentiation [GO:0045661]; regulation of stem cell proliferation [GO:0072091]; response to wounding [GO:0009611]; spongiotrophoblast layer development [GO:0060712]; T cell differentiation in thymus [GO:0033077]; vasculogenesis [GO:0001570]"	GO:0000165; GO:0000288; GO:0000932; GO:0001570; GO:0003342; GO:0003677; GO:0003700; GO:0003729; GO:0003730; GO:0005634; GO:0005737; GO:0005829; GO:0006915; GO:0007507; GO:0008283; GO:0009611; GO:0010468; GO:0010837; GO:0014065; GO:0021915; GO:0030529; GO:0031086; GO:0031440; GO:0032869; GO:0033077; GO:0035264; GO:0035925; GO:0038066; GO:0043488; GO:0043491; GO:0044344; GO:0044822; GO:0045600; GO:0045616; GO:0045647; GO:0045657; GO:0045661; GO:0046872; GO:0048382; GO:0051028; GO:0060710; GO:0060712; GO:0061158; GO:0070371; GO:0071320; GO:0071356; GO:0071364; GO:0071375; GO:0071385; GO:0071456; GO:0071472; GO:0071560; GO:0071889; GO:0072091; GO:0097403; GO:1900153; GO:1902172; GO:1904582; GO:1904628	0	0	0	PF04553;PF00642;	1069	m.62207	444133	28129368.4	19495068	2400805.333	6544654.906	78071.66667	364224	834174	1709445	66591.375	0.05353956
CHOYP_CATA.1.3	Q9PWF7	m.11120	sp	CATA_RUGRU	66.794	262	86	1	44	305	238	498	1.91E-124	369	CATA_RUGRU	reviewed	Catalase (EC 1.11.1.6)	cat	Rugosa rugosa (Japanese wrinkled frog) (Glandirana rugosa)	528	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	GO:0004096; GO:0005777; GO:0006979; GO:0020037; GO:0042744; GO:0046872	0	0	0	PF00199;PF06628;	1164	m.11120	217389.2857	189117.2222	414395.2	616062.8462	733193.4286	391679.2727	255387.3	239523.8333	424081.4	375916.75	0.777173169
CHOYP_CATA.2.3	Q9PWF7	m.18456	sp	CATA_RUGRU	62	150	56	1	1	150	350	498	4.98E-58	192	CATA_RUGRU	reviewed	Catalase (EC 1.11.1.6)	cat	Rugosa rugosa (Japanese wrinkled frog) (Glandirana rugosa)	528	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	GO:0004096; GO:0005777; GO:0006979; GO:0020037; GO:0042744; GO:0046872	0	0	0	PF00199;PF06628;	1165	m.18454	564396.7647	367283.6364	705840.0714	416959.6667	404097.5455	522593.3125	440098.7778	395214.6923	1367748.25	818153.3125	1.441405886
CHOYP_CATA.2.3	Q9PWF7	m.18456	sp	CATA_RUGRU	62	150	56	1	1	150	350	498	4.98E-58	192	CATA_RUGRU	reviewed	Catalase (EC 1.11.1.6)	cat	Rugosa rugosa (Japanese wrinkled frog) (Glandirana rugosa)	528	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	GO:0004096; GO:0005777; GO:0006979; GO:0020037; GO:0042744; GO:0046872	0	0	0	PF00199;PF06628;	1166	m.18456	59230.66667	218247.6667	549006.5	1407834.8	2466046.5	1077172.333	152714.6667	51178	83431	301492.6667	0.354438063
CHOYP_CATA.3.3	Q9PWF7	m.21642	sp	CATA_RUGRU	69.293	495	149	2	4	496	5	498	0	731	CATA_RUGRU	reviewed	Catalase (EC 1.11.1.6)	cat	Rugosa rugosa (Japanese wrinkled frog) (Glandirana rugosa)	528	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	GO:0004096; GO:0005777; GO:0006979; GO:0020037; GO:0042744; GO:0046872	0	0	0	PF00199;PF06628;	1167	m.21642	539767.45	313699.1765	367464.8696	950809.8889	538571.2	399029.9474	247616.3571	240972.5882	1029219.842	338429.12	0.832106181
CHOYP_CDC42.11.11	P57088	m.60003	sp	TMM33_HUMAN	57.2	250	99	2	18	266	5	247	2.58E-105	308	TMM33_HUMAN	reviewed	Transmembrane protein 33 (Protein DB83) (SHINC-3)	TMEM33 DB83	Homo sapiens (Human)	247	cellular protein localization [GO:0034613]; nuclear pore complex assembly [GO:0051292]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of PERK-mediated unfolded protein response [GO:1903899]; regulation of endoplasmic reticulum tubular network organization [GO:1903371]; response to endoplasmic reticulum stress [GO:0034976]	GO:0005635; GO:0005643; GO:0005783; GO:0005789; GO:0017056; GO:0030176; GO:0034613; GO:0034976; GO:0042470; GO:0051292; GO:0070062; GO:1903371; GO:1903896; GO:1903899	0	0	0	PF03661;	1201	m.60003	50511	1288292.667	154726	483424	17327	311126	150562	43697.5	111626	2595968.333	1.611097117
CHOYP_CDC42.11.11	P57088	m.60003	sp	TMM33_HUMAN	57.2	250	99	2	18	266	5	247	2.58E-105	308	TMM33_HUMAN	reviewed	Transmembrane protein 33 (Protein DB83) (SHINC-3)	TMEM33 DB83	Homo sapiens (Human)	247	cellular protein localization [GO:0034613]; nuclear pore complex assembly [GO:0051292]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of PERK-mediated unfolded protein response [GO:1903899]; regulation of endoplasmic reticulum tubular network organization [GO:1903371]; response to endoplasmic reticulum stress [GO:0034976]	GO:0005635; GO:0005643; GO:0005783; GO:0005789; GO:0017056; GO:0030176; GO:0034613; GO:0034976; GO:0042470; GO:0051292; GO:0070062; GO:1903371; GO:1903896; GO:1903899	0	0	0	PF03661;	1202	m.60004	2441898.417	910542.3333	901104.8182	855902.1	519689.2222	1897418.667	573841.75	348511.6	6239206.846	2821932.615	2.110609798
CHOYP_CLAP1.6.6	Q7Z460	m.57823	sp	CLAP1_HUMAN	43.481	1534	650	30	4	1336	5	1522	0	1122	CLAP1_HUMAN	reviewed	CLIP-associating protein 1 (Cytoplasmic linker-associated protein 1) (Multiple asters homolog 1) (Protein Orbit homolog 1) (hOrbit1)	CLASP1 KIAA0622 MAST1	Homo sapiens (Human)	1538	"astral microtubule organization [GO:0030953]; cell division [GO:0051301]; establishment of epithelial cell polarity [GO:0090162]; establishment of mitotic spindle localization [GO:0040001]; establishment of spindle orientation [GO:0051294]; establishment or maintenance of cell polarity [GO:0007163]; exit from mitosis [GO:0010458]; G2/M transition of mitotic cell cycle [GO:0000086]; Golgi organization [GO:0007030]; microtubule anchoring [GO:0034453]; microtubule bundle formation [GO:0001578]; microtubule cytoskeleton organization [GO:0000226]; microtubule nucleation [GO:0007020]; microtubule organizing center organization [GO:0031023]; mitotic spindle assembly [GO:0090307]; mitotic spindle organization [GO:0007052]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of microtubule polymerization or depolymerization [GO:0031111]; negative regulation of stress fiber assembly [GO:0051497]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of exocytosis [GO:0045921]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of microtubule polymerization [GO:0031116]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of focal adhesion assembly [GO:0051893]; regulation of gastrulation [GO:0010470]; regulation of microtubule cytoskeleton organization [GO:0070507]; sister chromatid cohesion [GO:0007062]; vesicle targeting [GO:0006903]"	GO:0000086; GO:0000226; GO:0000776; GO:0000777; GO:0001578; GO:0002162; GO:0005794; GO:0005813; GO:0005828; GO:0005829; GO:0005876; GO:0005881; GO:0005938; GO:0006903; GO:0007020; GO:0007026; GO:0007030; GO:0007052; GO:0007062; GO:0007163; GO:0008017; GO:0010458; GO:0010470; GO:0010634; GO:0010717; GO:0016020; GO:0030953; GO:0030981; GO:0031023; GO:0031111; GO:0031116; GO:0031592; GO:0034453; GO:0035371; GO:0040001; GO:0043515; GO:0045180; GO:0045921; GO:0051010; GO:0051294; GO:0051301; GO:0051497; GO:0051893; GO:0070062; GO:0070507; GO:0090091; GO:0090162; GO:0090307; GO:1903690; GO:1904261	0	0	0	PF12348;	1258	m.57823	187317.5	28220	63959	72711	124219	60439	50122	38305.5	64282.66667	257908	0.988729986
CHOYP_CNA1.1.1	P63329	m.65403	sp	PP2BA_RAT	80.785	484	82	2	5	478	8	490	0	840	PP2BA_RAT	reviewed	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform (EC 3.1.3.16) (CAM-PRP catalytic subunit) (Calmodulin-dependent calcineurin A subunit alpha isoform)	Ppp3ca Calna	Rattus norvegicus (Rat)	521	calcineurin-NFAT signaling cascade [GO:0033173]; calcium ion transport [GO:0006816]; cardiac muscle hypertrophy in response to stress [GO:0014898]; cellular response to drug [GO:0035690]; cellular response to glucose stimulus [GO:0071333]; excitatory postsynaptic potential [GO:0060079]; G1/S transition of mitotic cell cycle [GO:0000082]; modulation of synaptic transmission [GO:0050804]; multicellular organismal response to stress [GO:0033555]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of chromatin binding [GO:0035562]; negative regulation of dendrite morphogenesis [GO:0050774]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cardiac muscle hypertrophy in response to stress [GO:1903244]; positive regulation of NFAT protein import into nucleus [GO:0051533]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein dephosphorylation [GO:0006470]; protein import into nucleus [GO:0006606]; response to amphetamine [GO:0001975]; response to calcium ion [GO:0051592]; skeletal muscle fiber development [GO:0048741]; transition between fast and slow fiber [GO:0014883]	GO:0000082; GO:0001975; GO:0004721; GO:0004722; GO:0004723; GO:0005516; GO:0005654; GO:0005739; GO:0005829; GO:0005955; GO:0006470; GO:0006606; GO:0006816; GO:0008144; GO:0014883; GO:0014898; GO:0016020; GO:0030018; GO:0033173; GO:0033192; GO:0033555; GO:0035562; GO:0035690; GO:0042383; GO:0045944; GO:0045955; GO:0046676; GO:0046872; GO:0046982; GO:0048741; GO:0050774; GO:0050804; GO:0051091; GO:0051533; GO:0051592; GO:0060079; GO:0071333; GO:0098794; GO:1903244	0	0	0	PF00149;	1274	m.65403	747862.5	102873.25	36953.75	267182.2	183411.5	188070.8	78226.5	183013.5	1031260.2	278815	1.31465896
CHOYP_CRYAB.2.5	P04792	m.23200	sp	HSPB1_HUMAN	37.234	94	57	2	46	138	89	181	2.28E-09	58.5	HSPB1_HUMAN	reviewed	Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27)	HSPB1 HSP27 HSP28	Homo sapiens (Human)	205	cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028	0	0	0	PF00011;	1763	m.23200	656032.1667	491253.6667	589739.5	275663.5	539560.6667	427730.8333	123881.8333	3278779.125	1646641	558611.7	2.364833254
CHOYP_CRYAB.2.5	P04792	m.23200	sp	HSPB1_HUMAN	37.234	94	57	2	46	138	89	181	2.28E-09	58.5	HSPB1_HUMAN	reviewed	Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27)	HSPB1 HSP27 HSP28	Homo sapiens (Human)	205	cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028	0	0	0	PF00011;	1764	m.23201	483273.625	372271.3333	7342004.5	286184.5	542089.5	246745.6667	4659260.889	1075265.714	1637214.4	3352081.083	1.215464473
CHOYP_CRYAB.2.5	P04792	m.23201	sp	HSPB1_HUMAN	38.667	75	43	2	49	121	95	168	3.24E-11	61.2	HSPB1_HUMAN	reviewed	Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27)	HSPB1 HSP27 HSP28	Homo sapiens (Human)	205	cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028	0	0	0	PF00011;	1763	m.23200	656032.1667	491253.6667	589739.5	275663.5	539560.6667	427730.8333	123881.8333	3278779.125	1646641	558611.7	2.364833254
CHOYP_CRYAB.2.5	P04792	m.23201	sp	HSPB1_HUMAN	38.667	75	43	2	49	121	95	168	3.24E-11	61.2	HSPB1_HUMAN	reviewed	Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27)	HSPB1 HSP27 HSP28	Homo sapiens (Human)	205	cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028	0	0	0	PF00011;	1764	m.23201	483273.625	372271.3333	7342004.5	286184.5	542089.5	246745.6667	4659260.889	1075265.714	1637214.4	3352081.083	1.215464473
CHOYP_CUL3B.1.1	Q6GPF3	m.61643	sp	CUL3B_XENLA	79.051	759	152	3	9	761	11	768	0	1267	CUL3B_XENLA	reviewed	Cullin-3-B (CUL-3-B)	cul3b	Xenopus laevis (African clawed frog)	768	cell migration [GO:0016477]; COPII vesicle coating [GO:0048208]; embryonic cleavage [GO:0040016]; ER to Golgi vesicle-mediated transport [GO:0006888]; integrin-mediated signaling pathway [GO:0007229]; mitotic metaphase plate congression [GO:0007080]; negative regulation of Rho protein signal transduction [GO:0035024]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein monoubiquitination [GO:0006513]; protein ubiquitination [GO:0016567]; stem cell division [GO:0017145]; stress fiber assembly [GO:0043149]	GO:0000139; GO:0005634; GO:0005827; GO:0006513; GO:0006888; GO:0007080; GO:0007229; GO:0016477; GO:0016567; GO:0017145; GO:0031463; GO:0035024; GO:0040016; GO:0043149; GO:0043161; GO:0045842; GO:0048208	PATHWAY: Protein modification; protein ubiquitination.	0	0	PF00888;PF10557;	1787	m.61643	27508	44495	20686	7288768	153071	80835	NA	118382	116628	324292.5556	0.106200673
CHOYP_CUL3B.1.1	Q6GPF3	m.61643	sp	CUL3B_XENLA	79.051	759	152	3	9	761	11	768	0	1267	CUL3B_XENLA	reviewed	Cullin-3-B (CUL-3-B)	cul3b	Xenopus laevis (African clawed frog)	768	cell migration [GO:0016477]; COPII vesicle coating [GO:0048208]; embryonic cleavage [GO:0040016]; ER to Golgi vesicle-mediated transport [GO:0006888]; integrin-mediated signaling pathway [GO:0007229]; mitotic metaphase plate congression [GO:0007080]; negative regulation of Rho protein signal transduction [GO:0035024]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein monoubiquitination [GO:0006513]; protein ubiquitination [GO:0016567]; stem cell division [GO:0017145]; stress fiber assembly [GO:0043149]	GO:0000139; GO:0005634; GO:0005827; GO:0006513; GO:0006888; GO:0007080; GO:0007229; GO:0016477; GO:0016567; GO:0017145; GO:0031463; GO:0035024; GO:0040016; GO:0043149; GO:0043161; GO:0045842; GO:0048208	PATHWAY: Protein modification; protein ubiquitination.	0	0	PF00888;PF10557;	1788	m.61644	629266.8571	263750.4286	1817248.9	351080.8	792957.8889	818487.25	917944	379689.6	10976977.5	756066.5556	3.593167992
CHOYP_CYT5.1.1	P14841	m.29962	sp	CYTC_RAT	30.208	96	63	2	3	95	35	129	9.33E-06	44.7	CYTC_RAT	reviewed	Cystatin-C (Cystatin-3)	Cst3	Rattus norvegicus (Rat)	140	"apoptotic process [GO:0006915]; brain development [GO:0007420]; cell activation [GO:0001775]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to oxidative stress [GO:0034599]; circadian sleep/wake cycle, REM sleep [GO:0042747]; embryo implantation [GO:0007566]; eye development [GO:0001654]; male gonad development [GO:0008584]; negative regulation of cell death [GO:0060548]; positive regulation of cell proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; regulation of programmed cell death [GO:0043067]; response to axon injury [GO:0048678]; response to carbohydrate [GO:0009743]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to inorganic substance [GO:0010035]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; salivary gland development [GO:0007431]; Sertoli cell development [GO:0060009]"	GO:0001654; GO:0001666; GO:0001775; GO:0002020; GO:0004869; GO:0005604; GO:0005615; GO:0005737; GO:0005764; GO:0005771; GO:0005783; GO:0006915; GO:0006979; GO:0007420; GO:0007431; GO:0007566; GO:0008284; GO:0008584; GO:0009636; GO:0009743; GO:0010035; GO:0014070; GO:0030414; GO:0030424; GO:0031667; GO:0031965; GO:0031982; GO:0032355; GO:0034599; GO:0042493; GO:0042747; GO:0042995; GO:0043025; GO:0043067; GO:0043292; GO:0045740; GO:0048471; GO:0048678; GO:0060009; GO:0060548; GO:0070301	0	0	0	PF00031;	1802	m.29960	66898.8	126269.5	64611	712184.25	326682.45	417565.75	530142	295340.6667	1428826.833	764116	2.649906952
CHOYP_CYT5.1.1	P14841	m.29962	sp	CYTC_RAT	30.208	96	63	2	3	95	35	129	9.33E-06	44.7	CYTC_RAT	reviewed	Cystatin-C (Cystatin-3)	Cst3	Rattus norvegicus (Rat)	140	"apoptotic process [GO:0006915]; brain development [GO:0007420]; cell activation [GO:0001775]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to oxidative stress [GO:0034599]; circadian sleep/wake cycle, REM sleep [GO:0042747]; embryo implantation [GO:0007566]; eye development [GO:0001654]; male gonad development [GO:0008584]; negative regulation of cell death [GO:0060548]; positive regulation of cell proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; regulation of programmed cell death [GO:0043067]; response to axon injury [GO:0048678]; response to carbohydrate [GO:0009743]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to inorganic substance [GO:0010035]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; salivary gland development [GO:0007431]; Sertoli cell development [GO:0060009]"	GO:0001654; GO:0001666; GO:0001775; GO:0002020; GO:0004869; GO:0005604; GO:0005615; GO:0005737; GO:0005764; GO:0005771; GO:0005783; GO:0006915; GO:0006979; GO:0007420; GO:0007431; GO:0007566; GO:0008284; GO:0008584; GO:0009636; GO:0009743; GO:0010035; GO:0014070; GO:0030414; GO:0030424; GO:0031667; GO:0031965; GO:0031982; GO:0032355; GO:0034599; GO:0042493; GO:0042747; GO:0042995; GO:0043025; GO:0043067; GO:0043292; GO:0045740; GO:0048471; GO:0048678; GO:0060009; GO:0060548; GO:0070301	0	0	0	PF00031;	1803	m.29962	183189	92815	172106	157191	244696	60465	108336	236467	107114	716706.5	1.445991574
CHOYP_DNJC3.1.1	Q27968	m.52309	sp	DNJC3_BOVIN	55.4	500	210	6	50	536	5	504	0	526	DNJC3_BOVIN	reviewed	"DnaJ homolog subfamily C member 3 (Interferon-induced, double-stranded RNA-activated protein kinase inhibitor) (Protein kinase inhibitor of 58 kDa) (Protein kinase inhibitor p58)"	DNAJC3 P58IPK	Bos taurus (Bovine)	504	cellular response to cold [GO:0070417]; negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation [GO:1903912]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of translation initiation in response to endoplasmic reticulum stress [GO:0036494]; response to unfolded protein [GO:0006986]	GO:0004860; GO:0005783; GO:0005829; GO:0006469; GO:0006986; GO:0019901; GO:0036494; GO:0070417; GO:1903912	0	0	cd06257;	PF00226;PF09976;PF13181;	1897	m.52309	680976.5	340475.7143	285811.25	195196.1111	87705.2	422222.4286	100637.6	1724223.714	462403.7143	208907.375	1.835278254
CHOYP_DPER_GL22446.1.1	P04792	m.52315	sp	HSPB1_HUMAN	37.838	74	45	1	28	100	95	168	1.34E-11	61.2	HSPB1_HUMAN	reviewed	Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27)	HSPB1 HSP27 HSP28	Homo sapiens (Human)	205	cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028	0	0	0	PF00011;	1903	m.52311	150372	1061472	56760	1460974	15160	131588.5	1822599	21110	39365	431946	0.891381436
CHOYP_DPER_GL22446.1.1	P04792	m.52315	sp	HSPB1_HUMAN	37.838	74	45	1	28	100	95	168	1.34E-11	61.2	HSPB1_HUMAN	reviewed	Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27)	HSPB1 HSP27 HSP28	Homo sapiens (Human)	205	cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028	0	0	0	PF00011;	1904	m.52315	636340	340809.8333	7943169.909	362777.6667	568209	237382.25	5959749.143	1408708.4	1734680.25	4352681.556	1.389988397
CHOYP_DPER_GL22446.1.1	P42930	m.52312	sp	HSPB1_RAT	35.443	79	50	1	46	123	93	171	3.49E-06	47.8	HSPB1_RAT	reviewed	Heat shock protein beta-1 (HspB1) (Heat shock 27 kDa protein) (HSP 27)	Hspb1 Hsp27	Rattus norvegicus (Rat)	206	aging [GO:0007568]; cellular response to butyrate [GO:1903545]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-11 [GO:0071348]; female pregnancy [GO:0007565]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced cell death [GO:1903202]; positive regulation of neuron projection development [GO:0010976]; response to angiotensin [GO:1990776]; response to ischemia [GO:0002931]; response to muscle stretch [GO:0035994]	GO:0000502; GO:0002931; GO:0005634; GO:0005737; GO:0005819; GO:0005886; GO:0007565; GO:0007568; GO:0010976; GO:0030424; GO:0030425; GO:0031430; GO:0031674; GO:0035994; GO:0043066; GO:0043130; GO:0043204; GO:0045202; GO:0070301; GO:0071348; GO:0097512; GO:0098839; GO:1903202; GO:1903545; GO:1990776	0	0	0	PF00011;	1903	m.52311	150372	1061472	56760	1460974	15160	131588.5	1822599	21110	39365	431946	0.891381436
CHOYP_DPER_GL22446.1.1	P42930	m.52312	sp	HSPB1_RAT	35.443	79	50	1	46	123	93	171	3.49E-06	47.8	HSPB1_RAT	reviewed	Heat shock protein beta-1 (HspB1) (Heat shock 27 kDa protein) (HSP 27)	Hspb1 Hsp27	Rattus norvegicus (Rat)	206	aging [GO:0007568]; cellular response to butyrate [GO:1903545]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-11 [GO:0071348]; female pregnancy [GO:0007565]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced cell death [GO:1903202]; positive regulation of neuron projection development [GO:0010976]; response to angiotensin [GO:1990776]; response to ischemia [GO:0002931]; response to muscle stretch [GO:0035994]	GO:0000502; GO:0002931; GO:0005634; GO:0005737; GO:0005819; GO:0005886; GO:0007565; GO:0007568; GO:0010976; GO:0030424; GO:0030425; GO:0031430; GO:0031674; GO:0035994; GO:0043066; GO:0043130; GO:0043204; GO:0045202; GO:0070301; GO:0071348; GO:0097512; GO:0098839; GO:1903202; GO:1903545; GO:1990776	0	0	0	PF00011;	1904	m.52315	636340	340809.8333	7943169.909	362777.6667	568209	237382.25	5959749.143	1408708.4	1734680.25	4352681.556	1.389988397
CHOYP_DUOX1.1.4	Q8HZK2	m.14285	sp	DUOX2_PIG	38.25	1634	853	34	28	1627	34	1545	0	1068	DUOX2_PIG	reviewed	Dual oxidase 2 (EC 1.11.1.-) (EC 1.6.3.1) (NADH/NADPH thyroid oxidase p138-tox)	DUOX2	Sus scrofa (Pig)	1545	cuticle development [GO:0042335]; cytokine-mediated signaling pathway [GO:0019221]; hormone biosynthetic process [GO:0042446]; hydrogen peroxide biosynthetic process [GO:0050665]; hydrogen peroxide catabolic process [GO:0042744]; oxidation-reduction process [GO:0055114]; response to cAMP [GO:0051591]; response to oxidative stress [GO:0006979]; thyroid hormone generation [GO:0006590]	GO:0004601; GO:0005509; GO:0006590; GO:0006979; GO:0016021; GO:0016174; GO:0016324; GO:0019221; GO:0020037; GO:0030054; GO:0042335; GO:0042446; GO:0042744; GO:0050665; GO:0051591; GO:0055114	PATHWAY: Hormone biosynthesis; thyroid hormone biosynthesis.	0	0	PF03098;PF00036;PF13202;PF08022;PF01794;PF08030;	1933	m.14284	298045.5	364715.8571	1546533.667	118162.1667	246316.5	298884.5	122879.75	125764	522952.75	1490645.4	0.995086091
CHOYP_DUOX1.1.4	Q8HZK2	m.14285	sp	DUOX2_PIG	38.25	1634	853	34	28	1627	34	1545	0	1068	DUOX2_PIG	reviewed	Dual oxidase 2 (EC 1.11.1.-) (EC 1.6.3.1) (NADH/NADPH thyroid oxidase p138-tox)	DUOX2	Sus scrofa (Pig)	1545	cuticle development [GO:0042335]; cytokine-mediated signaling pathway [GO:0019221]; hormone biosynthetic process [GO:0042446]; hydrogen peroxide biosynthetic process [GO:0050665]; hydrogen peroxide catabolic process [GO:0042744]; oxidation-reduction process [GO:0055114]; response to cAMP [GO:0051591]; response to oxidative stress [GO:0006979]; thyroid hormone generation [GO:0006590]	GO:0004601; GO:0005509; GO:0006590; GO:0006979; GO:0016021; GO:0016174; GO:0016324; GO:0019221; GO:0020037; GO:0030054; GO:0042335; GO:0042446; GO:0042744; GO:0050665; GO:0051591; GO:0055114	PATHWAY: Hormone biosynthesis; thyroid hormone biosynthesis.	0	0	PF03098;PF00036;PF13202;PF08022;PF01794;PF08030;	1934	m.14285	310680	17683	24969	166763.3333	218740	979111.5	52798	23701	203451	46921	1.767623232
CHOYP_DUOX1.2.4	Q8HZK2	m.33964	sp	DUOX2_PIG	39.888	1612	853	34	6	1572	5	1545	0	1139	DUOX2_PIG	reviewed	Dual oxidase 2 (EC 1.11.1.-) (EC 1.6.3.1) (NADH/NADPH thyroid oxidase p138-tox)	DUOX2	Sus scrofa (Pig)	1545	cuticle development [GO:0042335]; cytokine-mediated signaling pathway [GO:0019221]; hormone biosynthetic process [GO:0042446]; hydrogen peroxide biosynthetic process [GO:0050665]; hydrogen peroxide catabolic process [GO:0042744]; oxidation-reduction process [GO:0055114]; response to cAMP [GO:0051591]; response to oxidative stress [GO:0006979]; thyroid hormone generation [GO:0006590]	GO:0004601; GO:0005509; GO:0006590; GO:0006979; GO:0016021; GO:0016174; GO:0016324; GO:0019221; GO:0020037; GO:0030054; GO:0042335; GO:0042446; GO:0042744; GO:0050665; GO:0051591; GO:0055114	PATHWAY: Hormone biosynthesis; thyroid hormone biosynthesis.	0	0	PF03098;PF00036;PF13202;PF08022;PF01794;PF08030;	1935	m.33964	140121.5	25799	323976.3333	126041	497758.75	503392	35481	2397699.25	556731.5	66118.33333	3.196042923
CHOYP_DUOX1.4.4	Q8HZK2	m.44612	sp	DUOX2_PIG	38.372	1634	851	34	28	1627	34	1545	0	1072	DUOX2_PIG	reviewed	Dual oxidase 2 (EC 1.11.1.-) (EC 1.6.3.1) (NADH/NADPH thyroid oxidase p138-tox)	DUOX2	Sus scrofa (Pig)	1545	cuticle development [GO:0042335]; cytokine-mediated signaling pathway [GO:0019221]; hormone biosynthetic process [GO:0042446]; hydrogen peroxide biosynthetic process [GO:0050665]; hydrogen peroxide catabolic process [GO:0042744]; oxidation-reduction process [GO:0055114]; response to cAMP [GO:0051591]; response to oxidative stress [GO:0006979]; thyroid hormone generation [GO:0006590]	GO:0004601; GO:0005509; GO:0006590; GO:0006979; GO:0016021; GO:0016174; GO:0016324; GO:0019221; GO:0020037; GO:0030054; GO:0042335; GO:0042446; GO:0042744; GO:0050665; GO:0051591; GO:0055114	PATHWAY: Hormone biosynthesis; thyroid hormone biosynthesis.	0	0	PF03098;PF00036;PF13202;PF08022;PF01794;PF08030;	1936	m.44612	310680	17683	24969	166763.3333	218740	979111.5	52798	23701	203451	46921	1.767623232
CHOYP_DUOX1.4.4	Q8HZK2	m.44612	sp	DUOX2_PIG	38.372	1634	851	34	28	1627	34	1545	0	1072	DUOX2_PIG	reviewed	Dual oxidase 2 (EC 1.11.1.-) (EC 1.6.3.1) (NADH/NADPH thyroid oxidase p138-tox)	DUOX2	Sus scrofa (Pig)	1545	cuticle development [GO:0042335]; cytokine-mediated signaling pathway [GO:0019221]; hormone biosynthetic process [GO:0042446]; hydrogen peroxide biosynthetic process [GO:0050665]; hydrogen peroxide catabolic process [GO:0042744]; oxidation-reduction process [GO:0055114]; response to cAMP [GO:0051591]; response to oxidative stress [GO:0006979]; thyroid hormone generation [GO:0006590]	GO:0004601; GO:0005509; GO:0006590; GO:0006979; GO:0016021; GO:0016174; GO:0016324; GO:0019221; GO:0020037; GO:0030054; GO:0042335; GO:0042446; GO:0042744; GO:0050665; GO:0051591; GO:0055114	PATHWAY: Hormone biosynthesis; thyroid hormone biosynthesis.	0	0	PF03098;PF00036;PF13202;PF08022;PF01794;PF08030;	1937	m.44613	54325.25	409026.6667	302146.4	103545.3333	208297.6	35503	28723.5	17213.66667	95731	3884256.182	3.769861544
CHOYP_DVIR_GJ11008.1.1	P20073	m.11917	sp	ANXA7_HUMAN	46.129	310	167	0	3	312	177	486	6.10E-95	292	ANXA7_HUMAN	reviewed	Annexin A7 (Annexin VII) (Annexin-7) (Synexin)	ANXA7 ANX7 SNX OK/SW-cl.95	Homo sapiens (Human)	488	autophagy [GO:0006914]; cell proliferation [GO:0008283]; cellular calcium ion homeostasis [GO:0006874]; cellular water homeostasis [GO:0009992]; epithelial cell differentiation [GO:0030855]; hemostasis [GO:0007599]; membrane fusion [GO:0061025]; negative regulation of gene expression [GO:0010629]; regulation of cell shape [GO:0008360]; response to calcium ion [GO:0051592]; response to organic cyclic compound [GO:0014070]; response to salt stress [GO:0009651]; social behavior [GO:0035176]	GO:0005178; GO:0005509; GO:0005544; GO:0005634; GO:0005635; GO:0005789; GO:0005829; GO:0005886; GO:0006874; GO:0006914; GO:0007599; GO:0008283; GO:0008360; GO:0009651; GO:0009992; GO:0010629; GO:0014070; GO:0016020; GO:0030855; GO:0035176; GO:0044822; GO:0048306; GO:0051592; GO:0061025; GO:0070062	0	0	0	PF00191;	1938	m.11917	6301442	231217.3333	797249.3333	720519.8	957503.25	12720984.6	48237588.56	633734	2211074.5	13962189.6	8.633010741
CHOYP_DVIR_GJ19769.1.1	Q5R896	m.46852	sp	EVL_PONAB	38.785	428	213	13	299	696	9	417	9.62E-51	185	EVL_PONAB	reviewed	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein-like)	EVL	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	422	actin polymerization or depolymerization [GO:0008154]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of ruffle assembly [GO:1900028]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of stress fiber assembly [GO:0051496]; protein homotetramerization [GO:0051289]	GO:0005737; GO:0005856; GO:0005925; GO:0008154; GO:0010633; GO:0016020; GO:0030027; GO:0030838; GO:0051289; GO:0051496; GO:1900028	0	0	0	PF08776;PF00568;	1940	m.46852	163368.3333	378904	118704	277027	448469.3333	173383	111854.5	131192	246491	148739.5	0.585413632
CHOYP_DYHC1.1.1	Q14204	m.2432	sp	DYHC1_HUMAN	72.34	4653	1250	21	10	4647	16	4646	0	7099	DYHC1_HUMAN	reviewed	"Cytoplasmic dynein 1 heavy chain 1 (Cytoplasmic dynein heavy chain 1) (Dynein heavy chain, cytosolic)"	DYNC1H1 DHC1 DNCH1 DNCL DNECL DYHC KIAA0325	Homo sapiens (Human)	4646	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cytoplasmic mRNA processing body assembly [GO:0033962]; ER to Golgi vesicle-mediated transport [GO:0006888]; establishment of spindle localization [GO:0051293]; G2/M transition of mitotic cell cycle [GO:0000086]; microtubule-based movement [GO:0007018]; mitotic spindle organization [GO:0007052]; stress granule assembly [GO:0034063]	GO:0000086; GO:0003777; GO:0005524; GO:0005813; GO:0005829; GO:0005868; GO:0005874; GO:0006888; GO:0007018; GO:0007052; GO:0016020; GO:0016887; GO:0019886; GO:0030175; GO:0031012; GO:0033962; GO:0034063; GO:0044822; GO:0051293; GO:0051959; GO:0070062	0	0	0	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;	1960	m.2432	887226.7813	1223529.886	508584.2208	1126328.169	1045237.771	444423.2712	259077.8594	568284.55	2313205.671	404661.8052	0.832755322
CHOYP_EIF3C.1.1	Q9Y297	m.7992	sp	FBW1A_HUMAN	79.92	498	84	4	33	528	121	604	0	833	FBW1A_HUMAN	reviewed	F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)	BTRC BTRCP FBW1A FBXW1A	Homo sapiens (Human)	605	"branching involved in mammary gland duct morphogenesis [GO:0060444]; cellular response to organic cyclic compound [GO:0071407]; Fc-epsilon receptor signaling pathway [GO:0038095]; G2/M transition of mitotic cell cycle [GO:0000086]; mammary gland epithelial cell proliferation [GO:0033598]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of proteolysis [GO:0045862]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition [GO:0051437]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein dephosphorylation [GO:0006470]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of circadian rhythm [GO:0042752]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of proteasomal protein catabolic process [GO:0061136]; rhythmic process [GO:0048511]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]"	GO:0000086; GO:0000209; GO:0002223; GO:0004842; GO:0005654; GO:0005829; GO:0006470; GO:0006511; GO:0007165; GO:0008013; GO:0016032; GO:0016055; GO:0016567; GO:0016874; GO:0019005; GO:0031146; GO:0031648; GO:0033598; GO:0038061; GO:0038095; GO:0042752; GO:0042753; GO:0043122; GO:0043161; GO:0043433; GO:0045862; GO:0045879; GO:0045892; GO:0045893; GO:0048511; GO:0050852; GO:0051403; GO:0051437; GO:0060444; GO:0060828; GO:0061136; GO:0061630; GO:0071407	PATHWAY: Protein modification; protein ubiquitination.	0	0	PF12125;PF12937;PF00400;	2050	m.7991	443355.3529	594059.7619	922474.25	704320.2143	613616.0313	752316.1923	763908.2069	796613.8571	1069667.267	992001.5	1.334575888
CHOYP_EIF3C.1.1	Q9Y297	m.7992	sp	FBW1A_HUMAN	79.92	498	84	4	33	528	121	604	0	833	FBW1A_HUMAN	reviewed	F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)	BTRC BTRCP FBW1A FBXW1A	Homo sapiens (Human)	605	"branching involved in mammary gland duct morphogenesis [GO:0060444]; cellular response to organic cyclic compound [GO:0071407]; Fc-epsilon receptor signaling pathway [GO:0038095]; G2/M transition of mitotic cell cycle [GO:0000086]; mammary gland epithelial cell proliferation [GO:0033598]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of proteolysis [GO:0045862]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition [GO:0051437]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein dephosphorylation [GO:0006470]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of circadian rhythm [GO:0042752]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of proteasomal protein catabolic process [GO:0061136]; rhythmic process [GO:0048511]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]"	GO:0000086; GO:0000209; GO:0002223; GO:0004842; GO:0005654; GO:0005829; GO:0006470; GO:0006511; GO:0007165; GO:0008013; GO:0016032; GO:0016055; GO:0016567; GO:0016874; GO:0019005; GO:0031146; GO:0031648; GO:0033598; GO:0038061; GO:0038095; GO:0042752; GO:0042753; GO:0043122; GO:0043161; GO:0043433; GO:0045862; GO:0045879; GO:0045892; GO:0045893; GO:0048511; GO:0050852; GO:0051403; GO:0051437; GO:0060444; GO:0060828; GO:0061136; GO:0061630; GO:0071407	PATHWAY: Protein modification; protein ubiquitination.	0	0	PF12125;PF12937;PF00400;	2051	m.7993	4186454.4	4579665.1	5325869	4242813.909	3604237.818	1403465.5	5848178	3184518.5	9245060.5	377188	0.914279307
CHOYP_ERP44.1.1	Q3T0L2	m.3853	sp	ERP44_BOVIN	51.456	412	175	3	38	449	16	402	1.63E-148	431	ERP44_BOVIN	reviewed	Endoplasmic reticulum resident protein 44 (ER protein 44) (ERp44) (Thioredoxin domain-containing protein 4)	ERP44 TXNDC4	Bos taurus (Bovine)	406	cell redox homeostasis [GO:0045454]; glycoprotein metabolic process [GO:0009100]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976]; response to unfolded protein [GO:0006986]	GO:0003756; GO:0005783; GO:0005788; GO:0005789; GO:0005793; GO:0006457; GO:0006986; GO:0009100; GO:0009986; GO:0034976; GO:0045454; GO:0070062	0	0	0	PF00085;	2111	m.3853	333622	278313.1111	245562	284246.3	516294.1538	130593.5556	290801.2222	469337.4444	364207.1429	965848.8333	1.33940765
CHOYP_ETFD.1.1	Q921G7	m.6881	sp	ETFD_MOUSE	74.787	587	144	3	35	619	32	616	0	936	ETFD_MOUSE	reviewed	"Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial (ETF-QO) (ETF-ubiquinone oxidoreductase) (EC 1.5.5.1) (Electron-transferring-flavoprotein dehydrogenase) (ETF dehydrogenase)"	Etfdh	Mus musculus (Mouse)	616	electron transport chain [GO:0022900]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; response to oxidative stress [GO:0006979]	GO:0004174; GO:0005739; GO:0005743; GO:0006979; GO:0009055; GO:0016020; GO:0016491; GO:0017133; GO:0022900; GO:0031305; GO:0031966; GO:0033539; GO:0043783; GO:0046872; GO:0048038; GO:0048039; GO:0051539	0	0	0	PF05187;	2113	m.6881	1514806.556	720342.7143	2784355.25	2616840.909	520876.8571	890803.6667	397596.4615	471962.2857	193417.75	552681.8889	0.307269064
CHOYP_FAS2.1.1	P13596	m.41201	sp	NCAM1_RAT	27.1	893	535	33	45	891	36	858	1.23E-61	228	NCAM1_RAT	reviewed	Neural cell adhesion molecule 1 (N-CAM-1) (NCAM-1) (CD antigen CD56)	Ncam1 Ncam	Rattus norvegicus (Rat)	858	aging [GO:0007568]; axon guidance [GO:0007411]; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules [GO:0016338]; cell adhesion [GO:0007155]; cellular response to inorganic substance [GO:0071241]; cellular response to molecule of bacterial origin [GO:0071219]; learning or memory [GO:0007611]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell death [GO:0060548]; neuron development [GO:0048666]; organ regeneration [GO:0031100]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; regulation of sensory perception of pain [GO:0051930]; regulation of synaptic plasticity [GO:0048167]; response to cocaine [GO:0042220]; response to drug [GO:0042493]; response to inorganic substance [GO:0010035]; response to lead ion [GO:0010288]; thalamus development [GO:0021794]	GO:0005104; GO:0005886; GO:0007155; GO:0007411; GO:0007568; GO:0007611; GO:0008092; GO:0008201; GO:0010035; GO:0010288; GO:0014012; GO:0016021; GO:0016338; GO:0019902; GO:0021794; GO:0030275; GO:0030426; GO:0031100; GO:0033555; GO:0042220; GO:0042493; GO:0043025; GO:0048167; GO:0048666; GO:0051930; GO:0060045; GO:0060548; GO:0071219; GO:0071241	0	0	0	PF00041;PF07679;	2138	m.41201	315614.8	924341.0769	525327.9231	1395813.25	906999.95	939825.6667	1610179.563	505503.4444	4964075.667	2869105.8	2.676605337
CHOYP_FYNA.1.1	P00523	m.63901	sp	SRC_CHICK	58.193	476	189	5	29	503	66	532	0	575	SRC_CHICK	reviewed	Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)	SRC	Gallus gallus (Chicken)	533	angiotensin-activated signaling pathway involved in heart process [GO:0086098]; bone resorption [GO:0045453]; cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell migration [GO:0016477]; cellular response to fluid shear stress [GO:0071498]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to reactive oxygen species [GO:0034614]; central nervous system development [GO:0007417]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; intracellular estrogen receptor signaling pathway [GO:0030520]; intracellular signal transduction [GO:0035556]; negative regulation of anoikis [GO:2000811]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of protein homooligomerization [GO:0032463]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; oogenesis [GO:0048477]; osteoclast development [GO:0036035]; peptidyl-tyrosine autophosphorylation [GO:0038083]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; progesterone receptor signaling pathway [GO:0050847]; protein destabilization [GO:0031648]; regulation of caveolin-mediated endocytosis [GO:2001286]; regulation of cell-cell adhesion [GO:0022407]; regulation of cell cycle [GO:0051726]; regulation of cell projection assembly [GO:0060491]; regulation of cell proliferation [GO:0042127]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of podosome assembly [GO:0071801]; regulation of protein binding [GO:0043393]; response to interleukin-1 [GO:0070555]; stress fiber assembly [GO:0043149]; substrate adhesion-dependent cell spreading [GO:0034446]; transforming growth factor beta receptor signaling pathway [GO:0007179]; uterus development [GO:0060065]	GO:0004713; GO:0004715; GO:0005524; GO:0005634; GO:0005743; GO:0005764; GO:0005770; GO:0005829; GO:0005884; GO:0005901; GO:0007049; GO:0007155; GO:0007173; GO:0007179; GO:0007229; GO:0007417; GO:0010008; GO:0010634; GO:0016477; GO:0019903; GO:0020037; GO:0022407; GO:0030520; GO:0030900; GO:0031234; GO:0031648; GO:0032211; GO:0032463; GO:0032587; GO:0033146; GO:0034446; GO:0034614; GO:0035556; GO:0036035; GO:0036120; GO:0038083; GO:0042127; GO:0043149; GO:0043154; GO:0043393; GO:0045087; GO:0045453; GO:0048008; GO:0048013; GO:0048471; GO:0048477; GO:0050847; GO:0051427; GO:0051726; GO:0051897; GO:0051902; GO:0051974; GO:0060065; GO:0060491; GO:0070062; GO:0070374; GO:0070555; GO:0070851; GO:0071498; GO:0071801; GO:0071803; GO:0071902; GO:0086098; GO:0090263; GO:2000394; GO:2000641; GO:2000811; GO:2001237; GO:2001243; GO:2001286	0	0	0	PF07714;PF00017;PF00018;	2200	m.63901	524788.6667	471083.5	3185989	208675.8571	755066.5	107169.1667	478132.5714	66267.66667	1700375.167	378622.5	0.530660215
CHOYP_G6PD.1.2	P05370	m.38380	sp	G6PD_RAT	68.487	476	140	5	62	530	9	481	0	692	G6PD_RAT	reviewed	Glucose-6-phosphate 1-dehydrogenase (G6PD) (EC 1.1.1.49)	G6pdx G6pd	Rattus norvegicus (Rat)	515	"cellular response to oxidative stress [GO:0034599]; cholesterol biosynthetic process [GO:0006695]; erythrocyte maturation [GO:0043249]; glucose 6-phosphate metabolic process [GO:0051156]; glucose metabolic process [GO:0006006]; glutathione metabolic process [GO:0006749]; NADPH regeneration [GO:0006740]; NADP metabolic process [GO:0006739]; negative regulation of cell growth involved in cardiac muscle cell development [GO:0061052]; negative regulation of protein glutathionylation [GO:0010734]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; pentose biosynthetic process [GO:0019322]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, oxidative branch [GO:0009051]; positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel [GO:1904879]; regulation of neuron apoptotic process [GO:0043523]; response to ethanol [GO:0045471]; response to food [GO:0032094]; response to iron(III) ion [GO:0010041]; response to organic cyclic compound [GO:0014070]; ribose phosphate biosynthetic process [GO:0046390]; substantia nigra development [GO:0021762]"	GO:0004345; GO:0005536; GO:0005634; GO:0005813; GO:0005829; GO:0006006; GO:0006098; GO:0006695; GO:0006739; GO:0006740; GO:0006749; GO:0009051; GO:0009898; GO:0010041; GO:0010734; GO:0014070; GO:0019322; GO:0021762; GO:0030246; GO:0032094; GO:0034599; GO:0043231; GO:0043249; GO:0043523; GO:0045471; GO:0046390; GO:0050661; GO:0051156; GO:0061052; GO:0070062; GO:1904879; GO:2000378	PATHWAY: Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.	0	0	PF02781;PF00479;	2201	m.38380	1144157	3013439.8	549546.5385	607411.3077	1562046.636	428645.9091	6152029.4	527677.4545	567266.2857	1130303.455	1.280563194
CHOYP_G6PD.2.2	P05370	m.46923	sp	G6PD_RAT	68.836	507	148	5	43	542	9	512	0	745	G6PD_RAT	reviewed	Glucose-6-phosphate 1-dehydrogenase (G6PD) (EC 1.1.1.49)	G6pdx G6pd	Rattus norvegicus (Rat)	515	"cellular response to oxidative stress [GO:0034599]; cholesterol biosynthetic process [GO:0006695]; erythrocyte maturation [GO:0043249]; glucose 6-phosphate metabolic process [GO:0051156]; glucose metabolic process [GO:0006006]; glutathione metabolic process [GO:0006749]; NADPH regeneration [GO:0006740]; NADP metabolic process [GO:0006739]; negative regulation of cell growth involved in cardiac muscle cell development [GO:0061052]; negative regulation of protein glutathionylation [GO:0010734]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; pentose biosynthetic process [GO:0019322]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, oxidative branch [GO:0009051]; positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel [GO:1904879]; regulation of neuron apoptotic process [GO:0043523]; response to ethanol [GO:0045471]; response to food [GO:0032094]; response to iron(III) ion [GO:0010041]; response to organic cyclic compound [GO:0014070]; ribose phosphate biosynthetic process [GO:0046390]; substantia nigra development [GO:0021762]"	GO:0004345; GO:0005536; GO:0005634; GO:0005813; GO:0005829; GO:0006006; GO:0006098; GO:0006695; GO:0006739; GO:0006740; GO:0006749; GO:0009051; GO:0009898; GO:0010041; GO:0010734; GO:0014070; GO:0019322; GO:0021762; GO:0030246; GO:0032094; GO:0034599; GO:0043231; GO:0043249; GO:0043523; GO:0045471; GO:0046390; GO:0050661; GO:0051156; GO:0061052; GO:0070062; GO:1904879; GO:2000378	PATHWAY: Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.	0	0	PF02781;PF00479;	2202	m.46923	1144157	3013439.8	549546.5385	607411.3077	1562046.636	428645.9091	6152029.4	527677.4545	567266.2857	1130303.455	1.280563194
CHOYP_GCN1L.1.1	E9PVA8	m.1352	sp	GCN1_MOUSE	51.119	2682	1286	16	6	2674	1	2670	0	2597	GCN1_MOUSE	reviewed	eIF-2-alpha kinase activator GCN1 (GCN1 eIF-2-alpha kinase activator homolog) (GCN1-like protein 1) (General control of amino-acid synthesis 1-like protein 1) (Translational activator GCN1)	Gcn1 Gcn1l1	Mus musculus (Mouse)	2671	cellular response to amino acid starvation [GO:0034198]; cellular response to leucine starvation [GO:1990253]; positive regulation of kinase activity [GO:0033674]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; regulation of translation [GO:0006417]	GO:0005737; GO:0005844; GO:0006417; GO:0016020; GO:0019887; GO:0033674; GO:0034198; GO:0036003; GO:0043022; GO:0044822; GO:1990253	0	0	0	0	2223	m.1352	1352037.714	432986.4483	1221570.564	434979.25	306553.9744	530097.3143	157778.9091	409519.0606	636971.027	1085987.286	0.752469935
CHOYP_GPX4-A.1.1	Q9N2J2	m.257	sp	GPX4_BOVIN	48.936	47	24	0	76	122	26	72	3.17E-10	58.2	GPX4_BOVIN	reviewed	"Phospholipid hydroperoxide glutathione peroxidase, mitochondrial (PHGPx) (EC 1.11.1.12) (Glutathione peroxidase 4) (GPx-4) (GSHPx-4)"	GPX4	Bos taurus (Bovine)	197	multicellular organism development [GO:0007275]; response to oxidative stress [GO:0006979]	GO:0004602; GO:0005739; GO:0006979; GO:0007275; GO:0047066	0	0	cd00340;	PF00255;	2274	m.257	1257869	1181418.714	722201.375	1275580.4	1345332.273	841702.7778	1320608	40145.66667	858260.5	240788.8571	0.570957526
CHOYP_GPX5.1.1	P30710	m.44157	sp	GPX5_RAT	54.237	118	47	3	1	113	97	212	1.71E-36	127	GPX5_RAT	reviewed	Epididymal secretory glutathione peroxidase (EC 1.11.1.9) (Epididymis-specific glutathione peroxidase-like protein) (EGLP) (Glutathione peroxidase 5) (GPx-5) (GSHPx-5)	Gpx5	Rattus norvegicus (Rat)	221	response to oxidative stress [GO:0006979]	GO:0004602; GO:0005576; GO:0006979	0	0	cd00340;	PF00255;	2275	m.44157	432304	537989.6667	130165	123239.5	109869.5	268769	428152	2047205	5811862.5	234411	6.591641144
CHOYP_GSH1.1.1	P19468	m.8927	sp	GSH1_RAT	61.836	621	215	11	1	615	1	605	0	785	GSH1_RAT	reviewed	Glutamate--cysteine ligase catalytic subunit (EC 6.3.2.2) (GCS heavy chain) (Gamma-ECS) (Gamma-glutamylcysteine synthetase)	Gclc Glclc	Rattus norvegicus (Rat)	637	"aging [GO:0007568]; apoptotic mitochondrial changes [GO:0008637]; cell redox homeostasis [GO:0045454]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to glucose stimulus [GO:0071333]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to insulin stimulus [GO:0032869]; cellular response to mechanical stimulus [GO:0071260]; cellular response to thyroxine stimulus [GO:0097069]; cysteine metabolic process [GO:0006534]; glutamate metabolic process [GO:0006536]; glutathione biosynthetic process [GO:0006750]; L-ascorbic acid metabolic process [GO:0019852]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of hepatic stellate cell activation [GO:2000490]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; regulation of blood vessel size [GO:0050880]; regulation of mitochondrial depolarization [GO:0051900]; response to activity [GO:0014823]; response to arsenic-containing substance [GO:0046685]; response to cadmium ion [GO:0046686]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to human chorionic gonadotropin [GO:0044752]; response to interleukin-1 [GO:0070555]; response to nitrosative stress [GO:0051409]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to xenobiotic stimulus [GO:0009410]"	GO:0000287; GO:0004357; GO:0005524; GO:0005829; GO:0006534; GO:0006536; GO:0006750; GO:0006979; GO:0007568; GO:0007584; GO:0008637; GO:0009408; GO:0009410; GO:0009725; GO:0014823; GO:0016595; GO:0017109; GO:0019852; GO:0031397; GO:0032436; GO:0032869; GO:0035729; GO:0043066; GO:0043524; GO:0043531; GO:0044344; GO:0044752; GO:0045454; GO:0045892; GO:0046685; GO:0046686; GO:0046982; GO:0050662; GO:0050880; GO:0051409; GO:0051900; GO:0070555; GO:0071260; GO:0071333; GO:0071372; GO:0097069; GO:2000490; GO:2001237	PATHWAY: Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 1/2.	0	0	PF03074;	2281	m.8927	1286438.167	275908.8333	275332.2	1057362.25	582170.8	2091339.8	445481.6	1362115	407285.875	7113066.077	3.284035466
CHOYP_GSK3B.1.1	Q9WV60	m.62139	sp	GSK3B_MOUSE	79.167	408	78	4	1	401	1	408	0	666	GSK3B_MOUSE	reviewed	Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)	Gsk3b	Mus musculus (Mouse)	420	aging [GO:0007568]; axonogenesis [GO:0007409]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in positive regulation of apoptotic process [GO:0044337]; cell migration [GO:0016477]; cell proliferation [GO:0008283]; cellular response to dopamine [GO:1903351]; cellular response to erythropoietin [GO:0036018]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-3 [GO:0036016]; cellular response to iron(II) ion [GO:0071282]; cellular response to lithium ion [GO:0071285]; cellular response to mechanical stimulus [GO:0071260]; circadian rhythm [GO:0007623]; cytoskeleton organization [GO:0007010]; epithelial to mesenchymal transition [GO:0001837]; ER overload response [GO:0006983]; establishment of cell polarity [GO:0030010]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fat cell differentiation [GO:0045444]; glycogen metabolic process [GO:0005977]; hippocampus development [GO:0021766]; hypermethylation of CpG island [GO:0044027]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; myoblast fusion [GO:0007520]; myotube differentiation [GO:0014902]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of dendrite morphogenesis [GO:0050774]; negative regulation of dopaminergic neuron differentiation [GO:1904339]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron maturation [GO:0014043]; negative regulation of neuron migration [GO:2001223]; negative regulation of neuron projection development [GO:0010977]; negative regulation of NFAT protein import into nucleus [GO:0051534]; negative regulation of nitric-oxide synthase activity [GO:0051001]; negative regulation of protein binding [GO:0032091]; negative regulation of protein complex assembly [GO:0031333]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; organ morphogenesis [GO:0009887]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; phosphorylation [GO:0016310]; positive regulation of axon extension [GO:0045773]; positive regulation of cardiac muscle cell differentiation [GO:2000727]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of GTPase activity [GO:0043547]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901030]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein binding [GO:0032092]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of stem cell differentiation [GO:2000738]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein autophosphorylation [GO:0046777]; protein export from nucleus [GO:0006611]; protein localization to microtubule [GO:0035372]; protein phosphorylation [GO:0006468]; re-entry into mitotic cell cycle [GO:0000320]; regulation of gene expression by genetic imprinting [GO:0006349]; regulation of microtubule-based process [GO:0032886]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of neuron projection development [GO:0010975]; response to activity [GO:0014823]; response to angiotensin [GO:1990776]; response to drug [GO:0042493]; response to epinephrine [GO:0071871]; response to estradiol [GO:0032355]; response to insulin [GO:0032868]; response to insulin-like growth factor stimulus [GO:1990418]; response to L-glutamate [GO:1902065]; response to ultrasound [GO:1990478]; superior temporal gyrus development [GO:0071109]; Wnt signaling pathway [GO:0016055]	GO:0000320; GO:0001085; GO:0001837; GO:0001954; GO:0002039; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005813; GO:0005829; GO:0005886; GO:0005977; GO:0006349; GO:0006468; GO:0006611; GO:0006983; GO:0007010; GO:0007409; GO:0007520; GO:0007568; GO:0007623; GO:0008013; GO:0008283; GO:0009887; GO:0010614; GO:0010628; GO:0010800; GO:0010918; GO:0010975; GO:0010977; GO:0014043; GO:0014069; GO:0014823; GO:0014902; GO:0016020; GO:0016055; GO:0016301; GO:0016310; GO:0016477; GO:0018105; GO:0018107; GO:0019901; GO:0021766; GO:0030010; GO:0030424; GO:0030426; GO:0030529; GO:0030877; GO:0031333; GO:0031334; GO:0031625; GO:0032091; GO:0032092; GO:0032355; GO:0032436; GO:0032868; GO:0032886; GO:0033138; GO:0034236; GO:0034392; GO:0035372; GO:0035556; GO:0035729; GO:0036016; GO:0036018; GO:0042493; GO:0043025; GO:0043066; GO:0043197; GO:0043198; GO:0043227; GO:0043407; GO:0043525; GO:0043547; GO:0044027; GO:0044297; GO:0044337; GO:0045121; GO:0045444; GO:0045773; GO:0045944; GO:0046777; GO:0046827; GO:0048168; GO:0048471; GO:0048661; GO:0050321; GO:0050774; GO:0051001; GO:0051059; GO:0051534; GO:0060070; GO:0070059; GO:0070301; GO:0071109; GO:0071260; GO:0071282; GO:0071285; GO:0071871; GO:0097192; GO:1901030; GO:1901216; GO:1902065; GO:1903351; GO:1904339; GO:1990418; GO:1990478; GO:1990776; GO:1990909; GO:2000463; GO:2000573; GO:2000727; GO:2000738; GO:2001223	0	0	0	PF00069;	2283	m.62139	1432424.833	243861	732079	327384.2	105283.3333	515224	2014174	669985	1655806.667	180484	1.772480218
CHOYP_HMCN1.44.44	A4IGL7	m.67044	sp	PXDN_XENTR	27.966	354	217	15	7	355	287	607	2.55E-29	124	PXDN_XENTR	reviewed	Peroxidasin (EC 1.11.1.7)	pxdn pxn	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	1457	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	GO:0004601; GO:0005576; GO:0006979; GO:0020037; GO:0042744; GO:0046872	0	0	0	PF03098;PF07679;PF13855;PF00093;	2324	m.67044	550553.4	25633	NA	616589.5	41867	860098	102608	122130.5	322093	1078181.333	1.610253998
CHOYP_HS12A.25.33	Q3SZZ2	m.60353	sp	XBP1_BOVIN	37.5	248	123	6	5	220	14	261	1.74E-35	129	XBP1_BOVIN	reviewed	"X-box-binding protein 1 (XBP-1) [Cleaved into: X-box-binding protein 1, cytoplasmic form; X-box-binding protein 1, luminal form]"	XBP1	Bos taurus (Bovine)	261	adipose tissue development [GO:0060612]; angiogenesis [GO:0001525]; cell growth [GO:0016049]; cellular response to amino acid stimulus [GO:0071230]; cellular response to fluid shear stress [GO:0071498]; cellular response to fructose stimulus [GO:0071332]; cellular response to glucose starvation [GO:0042149]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-4 [GO:0071353]; cellular response to laminar fluid shear stress [GO:0071499]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient [GO:0031670]; cellular response to oxidative stress [GO:0034599]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular triglyceride homeostasis [GO:0035356]; cholesterol homeostasis [GO:0042632]; endothelial cell proliferation [GO:0001935]; epithelial cell maturation involved in salivary gland development [GO:0060691]; exocrine pancreas development [GO:0031017]; fatty acid homeostasis [GO:0055089]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; liver development [GO:0001889]; muscle organ development [GO:0007517]; negative regulation of apoptotic process [GO:0043066]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of endoplasmic reticulum unfolded protein response [GO:1900102]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron development [GO:0048666]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of autophagy [GO:0010508]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of hepatocyte proliferation [GO:2000347]; positive regulation of histone methylation [GO:0031062]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of lactation [GO:1903489]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of plasma cell differentiation [GO:1900100]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein acetylation [GO:1901985]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of TOR signaling [GO:0032008]; positive regulation of transcription factor import into nucleus [GO:0042993]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response [GO:0006990]; protein destabilization [GO:0031648]; regulation of autophagy [GO:0010506]; response to endoplasmic reticulum stress [GO:0034976]; response to insulin-like growth factor stimulus [GO:1990418]; sterol homeostasis [GO:0055092]; transcription from RNA polymerase II promoter [GO:0006366]; ubiquitin-dependent protein catabolic process [GO:0006511]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	GO:0000122; GO:0000977; GO:0000981; GO:0001047; GO:0001158; GO:0001525; GO:0001889; GO:0001934; GO:0001935; GO:0002639; GO:0003700; GO:0005634; GO:0005737; GO:0005783; GO:0005829; GO:0006366; GO:0006511; GO:0006990; GO:0007517; GO:0010506; GO:0010508; GO:0010832; GO:0014065; GO:0016049; GO:0030176; GO:0031017; GO:0031062; GO:0031490; GO:0031648; GO:0031670; GO:0032008; GO:0032869; GO:0034599; GO:0034976; GO:0035356; GO:0035924; GO:0042149; GO:0042632; GO:0042993; GO:0043066; GO:0045348; GO:0045579; GO:0045582; GO:0045600; GO:0045944; GO:0046982; GO:0048010; GO:0048666; GO:0051024; GO:0055089; GO:0055092; GO:0060612; GO:0060691; GO:0070059; GO:0071222; GO:0071230; GO:0071332; GO:0071333; GO:0071353; GO:0071375; GO:0071498; GO:0071499; GO:1900100; GO:1900102; GO:1900103; GO:1901800; GO:1901985; GO:1902236; GO:1903489; GO:1990418; GO:2000347; GO:2000353; GO:2000778	0	0	0	PF07716;	2357	m.60352	1061063	2385709.5	2264897	94215	1001035	2731855.333	803975.6667	1957162	1148877	1970376	1.265219311
CHOYP_HS74L.1.1	O95757	m.24610	sp	HS74L_HUMAN	51.001	849	390	10	1	833	1	839	0	850	HS74L_HUMAN	reviewed	Heat shock 70 kDa protein 4L (Heat shock 70-related protein APG-1) (Osmotic stress protein 94)	HSPA4L APG1 OSP94	Homo sapiens (Human)	839	protein folding [GO:0006457]; response to unfolded protein [GO:0006986]	GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006457; GO:0006986	0	0	0	PF00012;	2362	m.24610	2872580.188	112740.7857	4411670.667	1201676.667	1124563.429	1094158.353	3284951.133	2351002.5	872038.6667	267942.5882	0.809411259
CHOYP_HS90A.1.3	P04809	m.7724	sp	HSP83_DROPS	80.184	434	84	1	18	451	269	700	0	735	HSP83_DROPS	reviewed	Heat shock protein 83 (HSP 82)	Hsp83 Hsp82 GA11622	Drosophila pseudoobscura pseudoobscura (Fruit fly)	717	protein folding [GO:0006457]; response to stress [GO:0006950]	GO:0005524; GO:0005737; GO:0006457; GO:0006950	0	0	0	PF02518;PF00183;	2363	m.7724	7325354.96	10949054.77	9864588.92	5515392.909	5017594.406	7180385.591	13770965.14	6327870.893	59548259.7	3882865.063	2.34563455
CHOYP_HS90A.2.3	Q90474	m.21992	sp	H90A1_DANRE	71.275	651	168	6	4	643	83	725	0	939	H90A1_DANRE	reviewed	Heat shock protein HSP 90-alpha 1	hsp90a.1 hsp90 hsp90a hsp90aa1 zgc:86652	Danio rerio (Zebrafish) (Brachydanio rerio)	725	leukocyte migration [GO:0050900]; muscle organ development [GO:0007517]; myofibril assembly [GO:0030239]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; protein folding [GO:0006457]; response to metal ion [GO:0010038]; response to stress [GO:0006950]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; skeletal myofibril assembly [GO:0014866]; striated muscle myosin thick filament assembly [GO:0071688]	GO:0005524; GO:0006457; GO:0006950; GO:0007517; GO:0010038; GO:0014866; GO:0030018; GO:0030235; GO:0030239; GO:0030240; GO:0030241; GO:0031672; GO:0042470; GO:0045429; GO:0048471; GO:0048769; GO:0050900; GO:0071688	0	0	0	PF02518;PF00183;	2364	m.21992	198417.3333	144770.5	696893.3333	272145	6118315.25	903979.6	8391114.667	1085952.25	321976.5	171559.3333	1.46349798
CHOYP_HS90A.3.3	Q90474	m.28299	sp	H90A1_DANRE	77.655	631	135	5	21	647	97	725	0	983	H90A1_DANRE	reviewed	Heat shock protein HSP 90-alpha 1	hsp90a.1 hsp90 hsp90a hsp90aa1 zgc:86652	Danio rerio (Zebrafish) (Brachydanio rerio)	725	leukocyte migration [GO:0050900]; muscle organ development [GO:0007517]; myofibril assembly [GO:0030239]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; protein folding [GO:0006457]; response to metal ion [GO:0010038]; response to stress [GO:0006950]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; skeletal myofibril assembly [GO:0014866]; striated muscle myosin thick filament assembly [GO:0071688]	GO:0005524; GO:0006457; GO:0006950; GO:0007517; GO:0010038; GO:0014866; GO:0030018; GO:0030235; GO:0030239; GO:0030240; GO:0030241; GO:0031672; GO:0042470; GO:0045429; GO:0048471; GO:0048769; GO:0050900; GO:0071688	0	0	0	PF02518;PF00183;	2365	m.28299	6336167.448	9992789.118	8415240.6	5084407.194	4785630.914	5979604.593	12388561.62	5766617.969	53132814.89	3463185.139	2.332300095
CHOYP_HS90A.3.3	Q90474	m.28299	sp	H90A1_DANRE	77.655	631	135	5	21	647	97	725	0	983	H90A1_DANRE	reviewed	Heat shock protein HSP 90-alpha 1	hsp90a.1 hsp90 hsp90a hsp90aa1 zgc:86652	Danio rerio (Zebrafish) (Brachydanio rerio)	725	leukocyte migration [GO:0050900]; muscle organ development [GO:0007517]; myofibril assembly [GO:0030239]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; protein folding [GO:0006457]; response to metal ion [GO:0010038]; response to stress [GO:0006950]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; skeletal myofibril assembly [GO:0014866]; striated muscle myosin thick filament assembly [GO:0071688]	GO:0005524; GO:0006457; GO:0006950; GO:0007517; GO:0010038; GO:0014866; GO:0030018; GO:0030235; GO:0030239; GO:0030240; GO:0030241; GO:0031672; GO:0042470; GO:0045429; GO:0048471; GO:0048769; GO:0050900; GO:0071688	0	0	0	PF02518;PF00183;	2366	m.28300	260097	594426.6	5273871.714	789097.5714	117454.5	6914007.714	5102818.375	3765063.375	1503822.571	1044424.091	2.605582547
CHOYP_HSP90AA1.1.1	Q90474	m.14867	sp	H90A1_DANRE	78.488	688	144	3	1	685	1	687	0	1094	H90A1_DANRE	reviewed	Heat shock protein HSP 90-alpha 1	hsp90a.1 hsp90 hsp90a hsp90aa1 zgc:86652	Danio rerio (Zebrafish) (Brachydanio rerio)	725	leukocyte migration [GO:0050900]; muscle organ development [GO:0007517]; myofibril assembly [GO:0030239]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; protein folding [GO:0006457]; response to metal ion [GO:0010038]; response to stress [GO:0006950]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; skeletal myofibril assembly [GO:0014866]; striated muscle myosin thick filament assembly [GO:0071688]	GO:0005524; GO:0006457; GO:0006950; GO:0007517; GO:0010038; GO:0014866; GO:0030018; GO:0030235; GO:0030239; GO:0030240; GO:0030241; GO:0031672; GO:0042470; GO:0045429; GO:0048471; GO:0048769; GO:0050900; GO:0071688	0	0	0	PF02518;PF00183;	2381	m.14867	5057275.892	8742467.487	6918216.243	4546101	4161302.634	5237264.258	11005770.52	4880322.079	44503170.89	2961469.233	2.330914197
CHOYP_HYOU1.3.3	Q9Y4L1	m.28442	sp	HYOU1_HUMAN	43.75	208	108	3	2	207	739	939	5.24E-41	154	HYOU1_HUMAN	reviewed	Hypoxia up-regulated protein 1 (150 kDa oxygen-regulated protein) (ORP-150) (170 kDa glucose-regulated protein) (GRP-170)	HYOU1 GRP170 ORP150	Homo sapiens (Human)	999	cellular response to hypoxia [GO:0071456]; ER to Golgi vesicle-mediated transport [GO:0006888]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903382]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; receptor-mediated endocytosis [GO:0006898]; response to endoplasmic reticulum stress [GO:0034976]; response to ischemia [GO:0002931]	GO:0002931; GO:0005524; GO:0005576; GO:0005783; GO:0005788; GO:0005790; GO:0005925; GO:0006888; GO:0006898; GO:0016020; GO:0034663; GO:0034976; GO:0036498; GO:0051087; GO:0070062; GO:0071456; GO:0071682; GO:1903298; GO:1903382	0	0	0	PF00012;	2406	m.28442	349834.6667	186919	5250015.75	857059	43037	349373.6667	765713.5	458386	121379.3333	39706.5	0.259397923
CHOYP_IF2A.1.1	P68101	m.13279	sp	IF2A_RAT	72.787	305	82	1	3	306	4	308	8.15E-165	464	IF2A_RAT	reviewed	Eukaryotic translation initiation factor 2 subunit 1 (Eukaryotic translation initiation factor 2 subunit alpha) (eIF-2-alpha) (eIF-2A) (eIF-2alpha)	Eif2s1 Eif2a	Rattus norvegicus (Rat)	315	aging [GO:0007568]; cellular response to amino acid starvation [GO:0034198]; cellular response to heat [GO:0034605]; cellular response to UV [GO:0034644]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of guanyl-nucleotide exchange factor activity [GO:1905098]; negative regulation of translational initiation in response to stress [GO:0032057]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of neuron death [GO:1901216]; positive regulation of type B pancreatic cell apoptotic process [GO:2000676]; protein autophosphorylation [GO:0046777]; response to endoplasmic reticulum stress [GO:0034976]; response to manganese-induced endoplasmic reticulum stress [GO:1990737]; translational initiation [GO:0006413]; xenophagy [GO:0098792]	GO:0002230; GO:0003743; GO:0005634; GO:0005737; GO:0005840; GO:0005850; GO:0005851; GO:0006413; GO:0007568; GO:0010494; GO:0016020; GO:0032057; GO:0033290; GO:0034198; GO:0034605; GO:0034644; GO:0034976; GO:0043022; GO:0043614; GO:0044207; GO:0044822; GO:0046777; GO:0070062; GO:0097451; GO:0098779; GO:0098792; GO:1901216; GO:1905098; GO:1990737; GO:2000676	0	0	0	PF07541;PF00575;	2413	m.13279	11019606.4	1964395.333	5446832.167	337367.8	300885.75	200185.2	238561.6667	147715	865800	391535	0.096690357
CHOYP_ISCW_ISCW000704.1.1	Q08E52	m.38250	sp	PAK1_BOVIN	37.132	272	141	6	62	311	75	338	4.04E-39	147	PAK1_BOVIN	reviewed	Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (Alpha-PAK) (p21-activated kinase 1) (PAK-1) (p65-PAK)	PAK1	Bos taurus (Bovine)	544	actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; branching morphogenesis of an epithelial tube [GO:0048754]; exocytosis [GO:0006887]; negative regulation of cell proliferation involved in contact inhibition [GO:0060244]; positive regulation of cell migration [GO:0030335]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of stress fiber assembly [GO:0051496]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; wound healing [GO:0042060]	GO:0001726; GO:0001934; GO:0004674; GO:0004702; GO:0005518; GO:0005524; GO:0005737; GO:0005794; GO:0005886; GO:0005911; GO:0005925; GO:0006468; GO:0006887; GO:0006915; GO:0007409; GO:0030036; GO:0030335; GO:0031532; GO:0032587; GO:0033138; GO:0033148; GO:0042060; GO:0043234; GO:0043507; GO:0046777; GO:0048754; GO:0051496; GO:0060244; GO:0071437	0	0	0	PF00786;PF00069;	2442	m.38250	245741.3	34537.33333	397327	125593	35677.125	480958.8	53658.42857	244053.5714	295609.5556	142820.75	1.45087171
CHOYP_ISCW_ISCW008219.1.2	P08228	m.46822	sp	SODC_MOUSE	70.588	153	45	0	4	156	2	154	1.28E-74	223	SODC_MOUSE	reviewed	Superoxide dismutase [Cu-Zn] (EC 1.15.1.1)	Sod1	Mus musculus (Mouse)	154	activation of MAPK activity [GO:0000187]; aging [GO:0007568]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antibiotic [GO:0046677]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to nutrient levels [GO:0031667]; response to organic substance [GO:0010033]; response to oxidative stress [GO:0006979]; response to reactive oxygen species [GO:0000302]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	GO:0000187; GO:0000302; GO:0000303; GO:0001541; GO:0001819; GO:0001895; GO:0001975; GO:0002262; GO:0004784; GO:0005507; GO:0005615; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005758; GO:0005764; GO:0005777; GO:0005829; GO:0005886; GO:0006749; GO:0006801; GO:0006879; GO:0006979; GO:0007283; GO:0007566; GO:0007568; GO:0007569; GO:0007605; GO:0007626; GO:0008089; GO:0008090; GO:0008217; GO:0008270; GO:0009408; GO:0010033; GO:0019226; GO:0019430; GO:0030346; GO:0031012; GO:0031045; GO:0031410; GO:0031667; GO:0032287; GO:0032839; GO:0032930; GO:0034465; GO:0035865; GO:0040014; GO:0042493; GO:0042542; GO:0042554; GO:0042802; GO:0043025; GO:0043066; GO:0043085; GO:0043087; GO:0043209; GO:0043234; GO:0043524; GO:0045471; GO:0045541; GO:0045859; GO:0046677; GO:0046688; GO:0046716; GO:0048365; GO:0048678; GO:0050665; GO:0051087; GO:0051881; GO:0060047; GO:0060052; GO:0060087; GO:0060088; GO:0070062; GO:0071276; GO:0071318; GO:0072593; GO:0097332; GO:1902177; GO:1904115	0	0	cd00305;	PF00080;	2475	m.46822	3670563.4	468776.25	492295.75	89802.83333	365171.2222	320819.5	281210	369576.8571	1610264.2	335148	0.573470124
CHOYP_ISCW_ISCW008219.2.2	P08228	m.63442	sp	SODC_MOUSE	70.588	153	45	0	4	156	2	154	1.28E-74	223	SODC_MOUSE	reviewed	Superoxide dismutase [Cu-Zn] (EC 1.15.1.1)	Sod1	Mus musculus (Mouse)	154	activation of MAPK activity [GO:0000187]; aging [GO:0007568]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antibiotic [GO:0046677]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to nutrient levels [GO:0031667]; response to organic substance [GO:0010033]; response to oxidative stress [GO:0006979]; response to reactive oxygen species [GO:0000302]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	GO:0000187; GO:0000302; GO:0000303; GO:0001541; GO:0001819; GO:0001895; GO:0001975; GO:0002262; GO:0004784; GO:0005507; GO:0005615; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005758; GO:0005764; GO:0005777; GO:0005829; GO:0005886; GO:0006749; GO:0006801; GO:0006879; GO:0006979; GO:0007283; GO:0007566; GO:0007568; GO:0007569; GO:0007605; GO:0007626; GO:0008089; GO:0008090; GO:0008217; GO:0008270; GO:0009408; GO:0010033; GO:0019226; GO:0019430; GO:0030346; GO:0031012; GO:0031045; GO:0031410; GO:0031667; GO:0032287; GO:0032839; GO:0032930; GO:0034465; GO:0035865; GO:0040014; GO:0042493; GO:0042542; GO:0042554; GO:0042802; GO:0043025; GO:0043066; GO:0043085; GO:0043087; GO:0043209; GO:0043234; GO:0043524; GO:0045471; GO:0045541; GO:0045859; GO:0046677; GO:0046688; GO:0046716; GO:0048365; GO:0048678; GO:0050665; GO:0051087; GO:0051881; GO:0060047; GO:0060052; GO:0060087; GO:0060088; GO:0070062; GO:0071276; GO:0071318; GO:0072593; GO:0097332; GO:1902177; GO:1904115	0	0	cd00305;	PF00080;	2476	m.63442	3670563.4	468776.25	492295.75	89802.83333	365171.2222	320819.5	281210	369576.8571	1610264.2	335148	0.573470124
CHOYP_ISCW_ISCW010532.1.4	Q9NL98	m.11493	sp	PRDX_ASCSU	74.359	195	50	0	44	238	1	195	9.37E-109	314	PRDX_ASCSU	reviewed	Peroxiredoxin (EC 1.11.1.15) (AsPrx) (Thioredoxin peroxidase)	0	Ascaris suum (Pig roundworm) (Ascaris lumbricoides)	195	cell redox homeostasis [GO:0045454]; response to oxidative stress [GO:0006979]	GO:0004601; GO:0005737; GO:0006979; GO:0008379; GO:0016209; GO:0045454	0	0	0	PF10417;PF00578;	2486	m.11493	512133.2857	399627.7778	254216.5714	592246.3333	459379.875	69883.16667	284040.1429	196095.6	1176951.833	368687	0.945009971
CHOYP_ISCW_ISCW010532.2.4	Q9NL98	m.35454	sp	PRDX_ASCSU	73.846	195	51	0	1	195	1	195	8.32E-109	312	PRDX_ASCSU	reviewed	Peroxiredoxin (EC 1.11.1.15) (AsPrx) (Thioredoxin peroxidase)	0	Ascaris suum (Pig roundworm) (Ascaris lumbricoides)	195	cell redox homeostasis [GO:0045454]; response to oxidative stress [GO:0006979]	GO:0004601; GO:0005737; GO:0006979; GO:0008379; GO:0016209; GO:0045454	0	0	0	PF10417;PF00578;	2487	m.35454	512133.2857	399627.7778	254216.5714	592246.3333	459379.875	69883.16667	284040.1429	196095.6	1176951.833	368687	0.945009971
CHOYP_ISCW_ISCW010532.3.4	Q9NL98	m.56458	sp	PRDX_ASCSU	74.359	195	50	0	31	225	1	195	7.54E-110	316	PRDX_ASCSU	reviewed	Peroxiredoxin (EC 1.11.1.15) (AsPrx) (Thioredoxin peroxidase)	0	Ascaris suum (Pig roundworm) (Ascaris lumbricoides)	195	cell redox homeostasis [GO:0045454]; response to oxidative stress [GO:0006979]	GO:0004601; GO:0005737; GO:0006979; GO:0008379; GO:0016209; GO:0045454	0	0	0	PF10417;PF00578;	2488	m.56458	512133.2857	399627.7778	254216.5714	592246.3333	459379.875	69883.16667	284040.1429	196095.6	1176951.833	368687	0.945009971
CHOYP_ISCW_ISCW010532.4.4	Q9NL98	m.62265	sp	PRDX_ASCSU	74.359	195	50	0	1	195	1	195	2.49E-109	313	PRDX_ASCSU	reviewed	Peroxiredoxin (EC 1.11.1.15) (AsPrx) (Thioredoxin peroxidase)	0	Ascaris suum (Pig roundworm) (Ascaris lumbricoides)	195	cell redox homeostasis [GO:0045454]; response to oxidative stress [GO:0006979]	GO:0004601; GO:0005737; GO:0006979; GO:0008379; GO:0016209; GO:0045454	0	0	0	PF10417;PF00578;	2489	m.62265	512133.2857	399627.7778	254216.5714	592246.3333	459379.875	69883.16667	284040.1429	196095.6	1176951.833	368687	0.945009971
CHOYP_ISCW_ISCW012366.1.1	P53563	m.3690	sp	B2CL1_RAT	30.921	152	96	3	130	273	82	232	7.48E-17	80.9	B2CL1_RAT	reviewed	Bcl-2-like protein 1 (Bcl2-L-1) (Apoptosis regulator Bcl-X)	Bcl2l1 Bclx Blc2l	Rattus norvegicus (Rat)	233	aging [GO:0007568]; apoptotic process [GO:0006915]; cerebral cortex development [GO:0021987]; cytokinesis [GO:0000910]; endocytosis [GO:0006897]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of apoptotic process [GO:0043066]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; ovarian follicle development [GO:0001541]; regulation of apoptotic process [GO:0042981]; response to electrical stimulus [GO:0051602]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to inorganic substance [GO:0010035]; response to ischemia [GO:0002931]; response to lead ion [GO:0010288]; response to organic cyclic compound [GO:0014070]; response to organonitrogen compound [GO:0010243]; response to oxidative stress [GO:0006979]; response to peptide hormone [GO:0043434]	GO:0000910; GO:0001541; GO:0001666; GO:0002931; GO:0005739; GO:0005740; GO:0005741; GO:0005743; GO:0005759; GO:0005813; GO:0005829; GO:0006897; GO:0006915; GO:0006979; GO:0007093; GO:0007568; GO:0008630; GO:0010035; GO:0010243; GO:0010288; GO:0014070; GO:0016021; GO:0021987; GO:0030054; GO:0030672; GO:0031965; GO:0042542; GO:0042803; GO:0042981; GO:0043027; GO:0043066; GO:0043434; GO:0046982; GO:0051400; GO:0051602; GO:0097192; GO:0097371; GO:2001243	0	0	0	PF00452;PF02180;	2495	m.3691	5954836.833	449406	266357.1667	375873	197061.8334	206763.75	2988434.8	1828123.5	183205.75	485289.75	0.785778999
CHOYP_ISCW_ISCW012366.1.1	P53563	m.3692	sp	B2CL1_RAT	30.921	152	96	3	115	258	82	232	7.30E-17	80.5	B2CL1_RAT	reviewed	Bcl-2-like protein 1 (Bcl2-L-1) (Apoptosis regulator Bcl-X)	Bcl2l1 Bclx Blc2l	Rattus norvegicus (Rat)	233	aging [GO:0007568]; apoptotic process [GO:0006915]; cerebral cortex development [GO:0021987]; cytokinesis [GO:0000910]; endocytosis [GO:0006897]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of apoptotic process [GO:0043066]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; ovarian follicle development [GO:0001541]; regulation of apoptotic process [GO:0042981]; response to electrical stimulus [GO:0051602]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to inorganic substance [GO:0010035]; response to ischemia [GO:0002931]; response to lead ion [GO:0010288]; response to organic cyclic compound [GO:0014070]; response to organonitrogen compound [GO:0010243]; response to oxidative stress [GO:0006979]; response to peptide hormone [GO:0043434]	GO:0000910; GO:0001541; GO:0001666; GO:0002931; GO:0005739; GO:0005740; GO:0005741; GO:0005743; GO:0005759; GO:0005813; GO:0005829; GO:0006897; GO:0006915; GO:0006979; GO:0007093; GO:0007568; GO:0008630; GO:0010035; GO:0010243; GO:0010288; GO:0014070; GO:0016021; GO:0021987; GO:0030054; GO:0030672; GO:0031965; GO:0042542; GO:0042803; GO:0042981; GO:0043027; GO:0043066; GO:0043434; GO:0046982; GO:0051400; GO:0051602; GO:0097192; GO:0097371; GO:2001243	0	0	0	PF00452;PF02180;	2495	m.3691	5954836.833	449406	266357.1667	375873	197061.8334	206763.75	2988434.8	1828123.5	183205.75	485289.75	0.785778999
CHOYP_ISCW_ISCW014481.1.1	P56524	m.61217	sp	HDAC4_HUMAN	44.028	1013	420	27	99	1005	93	1064	0	732	HDAC4_HUMAN	reviewed	Histone deacetylase 4 (HD4) (EC 3.5.1.98)	HDAC4 KIAA0288	Homo sapiens (Human)	1084	"B cell activation [GO:0042113]; B cell differentiation [GO:0030183]; cardiac muscle hypertrophy in response to stress [GO:0014898]; cellular response to mechanical stimulus [GO:0071260]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to tumor necrosis factor [GO:0071356]; chromatin modification [GO:0016568]; chromatin remodeling [GO:0006338]; histone deacetylation [GO:0016575]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; inflammatory response [GO:0006954]; negative regulation of cell proliferation [GO:0008285]; negative regulation of glycolytic process [GO:0045820]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nervous system development [GO:0007399]; osteoblast development [GO:0002076]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of cell proliferation [GO:0008284]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein sumoylation [GO:0033235]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of gene expression, epigenetic [GO:0040029]; regulation of protein binding [GO:0043393]; regulation of skeletal muscle fiber development [GO:0048742]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; response to drug [GO:0042493]; response to interleukin-1 [GO:0070555]; skeletal system development [GO:0001501]; transcription, DNA-templated [GO:0006351]"	GO:0000118; GO:0000122; GO:0001025; GO:0001047; GO:0001501; GO:0002076; GO:0003682; GO:0003714; GO:0004407; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006338; GO:0006351; GO:0006954; GO:0007399; GO:0008134; GO:0008270; GO:0008284; GO:0008285; GO:0010592; GO:0010832; GO:0010882; GO:0014894; GO:0014898; GO:0014911; GO:0016568; GO:0016575; GO:0017053; GO:0030018; GO:0030183; GO:0030955; GO:0031594; GO:0031672; GO:0032041; GO:0033235; GO:0033558; GO:0033613; GO:0034983; GO:0040029; GO:0042113; GO:0042493; GO:0042641; GO:0042826; GO:0043393; GO:0043433; GO:0043525; GO:0045668; GO:0045820; GO:0045892; GO:0045893; GO:0045944; GO:0048661; GO:0048742; GO:0051091; GO:0070491; GO:0070555; GO:0070932; GO:0070933; GO:0071260; GO:0071356; GO:0071374; GO:1903428	0	0	0	PF12203;PF00850;	2505	m.61217	1761534	1532941	3260356.75	682510	30869	NA	20216773.75	903436	3183750	95814	4.196317118
CHOYP_ISCW_ISCW014880.1.1	Q7L7X3	m.27977	sp	TAOK1_HUMAN	55.446	909	350	7	1	864	1	899	0	951	TAOK1_HUMAN	reviewed	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) (hKFC-B) (MARK Kinase) (MARKK) (Prostate-derived sterile 20-like kinase 2) (PSK-2) (PSK2) (Prostate-derived STE20-like kinase 2) (Thousand and one amino acid protein kinase 1) (TAOK1) (hTAOK1)	TAOK1 KIAA1361 MAP3K16 MARKK	Homo sapiens (Human)	1001	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; execution phase of apoptosis [GO:0097194]; G2 DNA damage checkpoint [GO:0031572]; positive regulation of JNK cascade [GO:0046330]; positive regulation of stress-activated MAPK cascade [GO:0032874]; protein phosphorylation [GO:0006468]; regulation of cytoskeleton organization [GO:0051493]; sister chromatid cohesion [GO:0007062]	GO:0004672; GO:0004674; GO:0004702; GO:0005524; GO:0005737; GO:0005829; GO:0006281; GO:0006468; GO:0006974; GO:0007062; GO:0016301; GO:0016740; GO:0031572; GO:0032874; GO:0046330; GO:0051493; GO:0070062; GO:0097194	0	0	0	PF00069;	2510	m.27977	427771	181109	482113	344678	730917	444137	104192	226972	79568	20568	0.404062517
CHOYP_ISCW_ISCW018425.1.1	P81623	m.35608	sp	ERP29_BOVIN	41.256	223	122	8	101	318	33	251	3.49E-45	157	ERP29_BOVIN	reviewed	Endoplasmic reticulum resident protein 29 (ERp29)	ERP29	Bos taurus (Bovine)	258	activation of MAPK activity [GO:0000187]; intracellular protein transport [GO:0006886]; negative regulation of gene expression [GO:0010629]; negative regulation of protein secretion [GO:0050709]; positive regulation of gene expression [GO:0010628]; protein folding [GO:0006457]; protein secretion [GO:0009306]; regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902235]	GO:0000187; GO:0005783; GO:0005788; GO:0006457; GO:0006886; GO:0009306; GO:0009986; GO:0010628; GO:0010629; GO:0016020; GO:0042470; GO:0050709; GO:0070062; GO:1902235	0	0	cd00238;	PF07749;PF07912;	2528	m.35608	69747.75	295087.25	108464.6667	51716.66667	69209.5	64239.75	64803.66667	3535293	193632.6667	100727.75	6.661939975
CHOYP_ISCW_ISCW020302.1.1	Q17QJ7	m.37564	sp	P5CR2_BOVIN	52.222	270	120	3	15	277	1	268	4.30E-90	275	P5CR2_BOVIN	reviewed	Pyrroline-5-carboxylate reductase 2 (P5C reductase 2) (P5CR 2) (EC 1.5.1.2)	PYCR2	Bos taurus (Bovine)	320	cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; proline biosynthetic process [GO:0006561]	GO:0004735; GO:0005739; GO:0006561; GO:0034599; GO:0055129	PATHWAY: Amino-acid biosynthesis; L-proline biosynthesis; L-proline from L-glutamate 5-semialdehyde: step 1/1.	0	0	PF03807;PF14748;	2548	m.37564	423721	660120	897143.25	6067678.857	956357	817179	447929.3333	523851.6667	158505.6667	139265	0.231729707
CHOYP_ISCW_ISCW022925.1.2	Q9UEW8	m.61535	sp	STK39_HUMAN	60.687	524	169	6	23	543	56	545	0	631	STK39_HUMAN	reviewed	STE20/SPS1-related proline-alanine-rich protein kinase (Ste-20-related kinase) (EC 2.7.11.1) (DCHT) (Serine/threonine-protein kinase 39)	STK39 SPAK	Homo sapiens (Human)	545	cellular hypotonic response [GO:0071476]; intracellular signal transduction [GO:0035556]; negative regulation of pancreatic juice secretion [GO:0090188]; negative regulation of potassium ion transmembrane transport [GO:1901380]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of rubidium ion transmembrane transporter activity [GO:2000687]; negative regulation of rubidium ion transport [GO:2000681]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of potassium ion transport [GO:0043268]; protein phosphorylation [GO:0006468]; regulation of blood pressure [GO:0008217]; regulation of inflammatory response [GO:0050727]; regulation of ion homeostasis [GO:2000021]; response to stress [GO:0006950]; signal transduction by protein phosphorylation [GO:0023014]	GO:0001933; GO:0004674; GO:0004702; GO:0005524; GO:0005634; GO:0005737; GO:0005856; GO:0006468; GO:0006950; GO:0008217; GO:0016323; GO:0016324; GO:0018105; GO:0018107; GO:0023014; GO:0035556; GO:0043268; GO:0050727; GO:0071476; GO:0090188; GO:1901017; GO:1901380; GO:2000021; GO:2000681; GO:2000687	0	0	0	PF12202;PF00069;	2562	m.61535	2399787.846	2505934.667	935534.4286	1839033.2	1872947.077	576080.5	1020774	580225.7	3821616.4	2506714.8	0.890317199
CHOYP_KDM1A.1.1	Q9C0D0	m.60230	sp	PHAR1_HUMAN	65.089	169	58	1	451	618	412	580	2.21E-58	209	PHAR1_HUMAN	reviewed	Phosphatase and actin regulator 1	PHACTR1 KIAA1733 RPEL1	Homo sapiens (Human)	580	actin cytoskeleton reorganization [GO:0031532]; actomyosin structure organization [GO:0031032]; cell motility [GO:0048870]; stress fiber assembly [GO:0043149]	GO:0003779; GO:0004864; GO:0005634; GO:0005829; GO:0008599; GO:0030054; GO:0031032; GO:0031532; GO:0043149; GO:0045202; GO:0048870	0	0	0	PF02755;	2621	m.60229	31950	39122	59251	NA	NA	13888506	NA	96991	NA	177643	108.6772097
CHOYP_KDM1A.1.1	Q9C0D0	m.60230	sp	PHAR1_HUMAN	65.089	169	58	1	451	618	412	580	2.21E-58	209	PHAR1_HUMAN	reviewed	Phosphatase and actin regulator 1	PHACTR1 KIAA1733 RPEL1	Homo sapiens (Human)	580	actin cytoskeleton reorganization [GO:0031532]; actomyosin structure organization [GO:0031032]; cell motility [GO:0048870]; stress fiber assembly [GO:0043149]	GO:0003779; GO:0004864; GO:0005634; GO:0005829; GO:0008599; GO:0030054; GO:0031032; GO:0031532; GO:0043149; GO:0045202; GO:0048870	0	0	0	PF02755;	2622	m.60231	140869	642343.2	127076	338620	173559.5	506683.75	72642.66667	173597.6667	87713.91667	449772.6	0.907163375
CHOYP_KS6A1.1.1	P51812	m.38386	sp	KS6A3_HUMAN	71.795	741	195	5	1	730	1	738	0	1105	KS6A3_HUMAN	reviewed	Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (p90RSK3) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPK-activated protein kinase 1b) (MAPKAP kinase 1b) (MAPKAPK-1b) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2)	RPS6KA3 ISPK1 MAPKAPK1B RSK2	Homo sapiens (Human)	740	cell cycle [GO:0007049]; central nervous system development [GO:0007417]; intracellular signal transduction [GO:0035556]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell growth [GO:0030307]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of DNA-templated transcription in response to stress [GO:0043620]; regulation of translation in response to stress [GO:0043555]; response to lipopolysaccharide [GO:0032496]; signal transduction [GO:0007165]; skeletal system development [GO:0001501]; toll-like receptor signaling pathway [GO:0002224]	GO:0000287; GO:0001501; GO:0002224; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0007049; GO:0007165; GO:0007417; GO:0016301; GO:0030307; GO:0032496; GO:0035556; GO:0043027; GO:0043066; GO:0043154; GO:0043555; GO:0043620; GO:0045597; GO:0045944	0	0	0	PF00069;PF00433;	2650	m.38386	1433008.647	11597379.08	629911.0909	266298.5833	375369.6923	494348.8571	1027168.417	2000882.083	1658894.647	390354.4286	0.389572175
CHOYP_KS6A1.1.1	P51812	m.38386	sp	KS6A3_HUMAN	71.795	741	195	5	1	730	1	738	0	1105	KS6A3_HUMAN	reviewed	Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (p90RSK3) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPK-activated protein kinase 1b) (MAPKAP kinase 1b) (MAPKAPK-1b) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2)	RPS6KA3 ISPK1 MAPKAPK1B RSK2	Homo sapiens (Human)	740	cell cycle [GO:0007049]; central nervous system development [GO:0007417]; intracellular signal transduction [GO:0035556]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell growth [GO:0030307]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of DNA-templated transcription in response to stress [GO:0043620]; regulation of translation in response to stress [GO:0043555]; response to lipopolysaccharide [GO:0032496]; signal transduction [GO:0007165]; skeletal system development [GO:0001501]; toll-like receptor signaling pathway [GO:0002224]	GO:0000287; GO:0001501; GO:0002224; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0007049; GO:0007165; GO:0007417; GO:0016301; GO:0030307; GO:0032496; GO:0035556; GO:0043027; GO:0043066; GO:0043154; GO:0043555; GO:0043620; GO:0045597; GO:0045944	0	0	0	PF00069;PF00433;	2651	m.38387	1312003.154	343031.5	1880393.818	120431.8889	1189529.556	128250.4444	26108355.3	3421062.375	1285026.125	431221.2222	6.475003251
CHOYP_LIPA1.1.1	Q13136	m.10892	sp	LIPA1_HUMAN	58.447	1172	406	18	1	1115	1	1148	0	1214	LIPA1_HUMAN	reviewed	Liprin-alpha-1 (LAR-interacting protein 1) (LIP-1) (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1)	PPFIA1 LIP1	Homo sapiens (Human)	1202	cell-matrix adhesion [GO:0007160]; glutamate secretion [GO:0014047]; negative regulation of establishment of protein localization to plasma membrane [GO:0090005]; negative regulation of stress fiber assembly [GO:0051497]; neurotransmitter secretion [GO:0007269]; signal transduction [GO:0007165]	GO:0004871; GO:0005737; GO:0005829; GO:0005925; GO:0007160; GO:0007165; GO:0007269; GO:0014047; GO:0048786; GO:0051497; GO:0090005	0	0	0	PF00536;PF07647;	2676	m.10892	26631	NA	76553649.33	100756	NA	235199	NA	88643	962654	332672.5	0.015836724
CHOYP_LOC100083074.1.1	Q08420	m.1592	sp	SODE_RAT	24.176	182	118	6	49	216	48	223	2.37E-09	58.9	SODE_RAT	reviewed	Extracellular superoxide dismutase [Cu-Zn] (EC-SOD) (EC 1.15.1.1) (Superoxide dismutase B)	Sod3 Sod-3	Rattus norvegicus (Rat)	244	response to copper ion [GO:0046688]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]; response to superoxide [GO:0000303]	GO:0000303; GO:0001666; GO:0004784; GO:0005507; GO:0005615; GO:0005634; GO:0005737; GO:0005802; GO:0006979; GO:0008270; GO:0031012; GO:0046688; GO:0070062	0	0	cd00305;	PF00080;	2703	m.1592	149280	127898	715463.6	218126.3333	144283	501606.1429	376881.6667	846515.83	427851.1667	385176.1667	1.873015184
CHOYP_LOC100114171.1.1	O42254	m.50280	sp	IF2B1_CHICK	35.333	600	342	13	22	601	1	574	9.14E-106	333	IF2B1_CHICK	reviewed	Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2 mRNA-binding protein 1) (IMP-1) (IGF-II mRNA-binding protein 1) (VICKZ family member 1) (Zip-code binding polypeptide) (Zipcode-binding protein 1) (ZBP-1)	IGF2BP1 VICKZ1 ZBP1	Gallus gallus (Chicken)	576	CRD-mediated mRNA stabilization [GO:0070934]; mRNA transport [GO:0051028]; negative regulation of translation [GO:0017148]; neuronal stem cell population maintenance [GO:0097150]; pallium cell proliferation in forebrain [GO:0022013]; positive regulation of neuron projection development [GO:0010976]; regulation of mRNA stability involved in response to stress [GO:0010610]	GO:0000166; GO:0003729; GO:0003730; GO:0005634; GO:0010494; GO:0010610; GO:0010976; GO:0017148; GO:0022013; GO:0030027; GO:0030175; GO:0030426; GO:0045182; GO:0048027; GO:0048471; GO:0051028; GO:0070934; GO:0070937; GO:0097150	0	0	0	PF00013;PF00076;	2706	m.50280	365245.2	211759.5455	573434.7059	582694.7857	1516110.75	917042.8333	1333250.333	482998.8462	1581996.059	366701.4286	1.440946903
CHOYP_LOC100114636.1.1	O43396	m.11052	sp	TXNL1_HUMAN	55.052	287	125	3	5	288	4	289	1.01E-113	332	TXNL1_HUMAN	reviewed	Thioredoxin-like protein 1 (32 kDa thioredoxin-related protein)	TXNL1 TRP32 TXL TXNL	Homo sapiens (Human)	289	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glycerol ether metabolic process [GO:0006662]; protein folding [GO:0006457]; sulfate assimilation [GO:0000103]	GO:0000103; GO:0000502; GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0006662; GO:0015035; GO:0015036; GO:0016671; GO:0034599; GO:0045454; GO:0070062	0	0	0	PF06201;PF00085;	2717	m.11052	504370.7143	84335	185717.4	6961696.571	399403.25	1272540.143	161912	197437.8	2654498.9	527442.625	0.59170523
CHOYP_LOC100121999.1.4	Q9Y6E0	m.23944	sp	STK24_HUMAN	71.429	350	87	5	8	350	28	371	1.30E-161	471	STK24_HUMAN	reviewed	Serine/threonine-protein kinase 24 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 3) (MST-3) (STE20-like kinase MST3) [Cleaved into: Serine/threonine-protein kinase 24 36 kDa subunit (Mammalian STE20-like protein kinase 3 N-terminal) (MST3/N); Serine/threonine-protein kinase 24 12 kDa subunit (Mammalian STE20-like protein kinase 3 C-terminal) (MST3/C)]	STK24 MST3 STK3	Homo sapiens (Human)	443	cellular component disassembly involved in execution phase of apoptosis [GO:0006921]; execution phase of apoptosis [GO:0097194]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; mitotic cell cycle [GO:0000278]; negative regulation of cell migration [GO:0030336]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of axon regeneration [GO:0048679]; response to hydrogen peroxide [GO:0042542]; signal transduction [GO:0007165]	GO:0000278; GO:0004672; GO:0004674; GO:0004702; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0005913; GO:0006468; GO:0006921; GO:0007165; GO:0008631; GO:0016020; GO:0030336; GO:0042542; GO:0046777; GO:0046872; GO:0048679; GO:0070062; GO:0097194; GO:0098641	0	0	0	PF00069;	2760	m.23944	246911.5	2041324	855477.3333	46377.5	2257489.75	1435030.5	825556.6667	121255.3333	287718	153497.75	0.518222441
CHOYP_LOC100121999.2.4	Q9Z2W1	m.44520	sp	STK25_MOUSE	78.618	304	63	2	9	310	13	316	3.44E-161	471	STK25_MOUSE	reviewed	Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response kinase 1) (SOK-1) (Ste20/oxidant stress response kinase 1)	Stk25 Sok1	Mus musculus (Mouse)	426	establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Golgi localization [GO:0051645]; Golgi reassembly [GO:0090168]; intrinsic apoptotic signaling pathway in response to hydrogen peroxide [GO:0036481]; positive regulation of axonogenesis [GO:0050772]; positive regulation of stress-activated MAPK cascade [GO:0032874]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; response to hydrogen peroxide [GO:0042542]	GO:0000139; GO:0004702; GO:0005524; GO:0005737; GO:0006468; GO:0007163; GO:0032874; GO:0036481; GO:0042542; GO:0042803; GO:0046777; GO:0046872; GO:0050772; GO:0051645; GO:0051683; GO:0070062; GO:0090168	0	0	0	PF00069;	2761	m.44520	246911.5	2041324	855477.3333	46377.5	2257489.75	1435030.5	825556.6667	121255.3333	287718	153497.75	0.518222441
CHOYP_LOC100121999.4.4	Q9Z2W1	m.63100	sp	STK25_MOUSE	78.618	304	63	2	9	310	13	316	1.42E-162	472	STK25_MOUSE	reviewed	Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response kinase 1) (SOK-1) (Ste20/oxidant stress response kinase 1)	Stk25 Sok1	Mus musculus (Mouse)	426	establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Golgi localization [GO:0051645]; Golgi reassembly [GO:0090168]; intrinsic apoptotic signaling pathway in response to hydrogen peroxide [GO:0036481]; positive regulation of axonogenesis [GO:0050772]; positive regulation of stress-activated MAPK cascade [GO:0032874]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; response to hydrogen peroxide [GO:0042542]	GO:0000139; GO:0004702; GO:0005524; GO:0005737; GO:0006468; GO:0007163; GO:0032874; GO:0036481; GO:0042542; GO:0042803; GO:0046777; GO:0046872; GO:0050772; GO:0051645; GO:0051683; GO:0070062; GO:0090168	0	0	0	PF00069;	2762	m.63100	246911.5	2041324	855477.3333	46377.5	2257489.75	1435030.5	825556.6667	121255.3333	287718	153497.75	0.518222441
CHOYP_LOC100160839.1.1	O00506	m.53063	sp	STK25_HUMAN	56.695	478	128	6	9	485	13	412	3.92E-168	484	STK25_HUMAN	reviewed	Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response kinase 1) (SOK-1) (Ste20/oxidant stress response kinase 1)	STK25 SOK1 YSK1	Homo sapiens (Human)	426	establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Golgi localization [GO:0051645]; Golgi reassembly [GO:0090168]; intrinsic apoptotic signaling pathway in response to hydrogen peroxide [GO:0036481]; positive regulation of axonogenesis [GO:0050772]; positive regulation of stress-activated MAPK cascade [GO:0032874]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; response to hydrogen peroxide [GO:0042542]; response to oxidative stress [GO:0006979]; signal transduction [GO:0007165]	GO:0000139; GO:0004672; GO:0004702; GO:0005524; GO:0005737; GO:0006468; GO:0006979; GO:0007163; GO:0007165; GO:0032874; GO:0036481; GO:0042542; GO:0042803; GO:0046777; GO:0046872; GO:0050772; GO:0051645; GO:0051683; GO:0070062; GO:0090168	0	0	0	PF00069;	2780	m.53063	246911.5	2041324	855477.3333	46377.5	2257489.75	1435030.5	825556.6667	121255.3333	287718	153497.75	0.518222441
CHOYP_LOC100169460.1.1	Q9UJZ1	m.41302	sp	STML2_HUMAN	62.876	299	111	0	37	335	22	320	8.71E-134	389	STML2_HUMAN	reviewed	"Stomatin-like protein 2, mitochondrial (SLP-2) (EPB72-like protein 2) (Paraprotein target 7) (Paratarg-7)"	STOML2 SLP2 HSPC108	Homo sapiens (Human)	356	"CD4-positive, alpha-beta T cell activation [GO:0035710]; cellular calcium ion homeostasis [GO:0006874]; interleukin-2 production [GO:0032623]; lipid localization [GO:0010876]; mitochondrial ATP synthesis coupled proton transport [GO:0042776]; mitochondrial calcium ion transport [GO:0006851]; mitochondrial protein processing [GO:0034982]; mitochondrion organization [GO:0007005]; positive regulation of cardiolipin metabolic process [GO:1900210]; positive regulation of mitochondrial DNA replication [GO:0090297]; positive regulation of mitochondrial membrane potential [GO:0010918]; protein oligomerization [GO:0051259]; stress-induced mitochondrial fusion [GO:1990046]; T cell receptor signaling pathway [GO:0050852]"	GO:0005102; GO:0005743; GO:0005758; GO:0005856; GO:0006851; GO:0006874; GO:0007005; GO:0010876; GO:0010918; GO:0019897; GO:0032623; GO:0034982; GO:0035710; GO:0042776; GO:0045121; GO:0050852; GO:0051020; GO:0051259; GO:0090297; GO:1900210; GO:1901612; GO:1990046	0	0	0	PF01145;PF16200;	2799	m.41302	162703	54117.4	99548	968465.375	170092.6	625394.3333	282617.2857	239068.4	164670.375	657196.8571	1.35329683
CHOYP_LOC100174996.1.1	P42297	m.27300	sp	YXIE_BACSU	27.586	145	97	4	4	141	5	148	2.50E-09	55.5	YXIE_BACSU	reviewed	Universal stress protein YxiE (USP YxiE)	yxiE BSU39250 N17E	Bacillus subtilis (strain 168)	148	response to stress [GO:0006950]	GO:0006950	0	0	0	PF00582;	2800	m.27300	15768	10356709	51504	92034	2104413.667	45672	14985274	31533	57969	138696	1.209082861
CHOYP_LOC100177679.1.1	P74148	m.54177	sp	Y1388_SYNY3	28.824	170	104	6	11	180	2	154	2.95E-13	67.4	Y1388_SYNY3	reviewed	Universal stress protein Sll1388 (USP Sll1388)	sll1388	Synechocystis sp. (strain PCC 6803 / Kazusa)	154	response to stress [GO:0006950]	GO:0006950	0	0	0	PF00582;	2812	m.54177	16813	149382	482708	31923	80985	808288	16392	2398202	1484143	203691	6.446108024
CHOYP_LOC100180023.1.7	P42297	m.11060	sp	YXIE_BACSU	26.974	152	94	5	6	148	5	148	7.42E-09	54.3	YXIE_BACSU	reviewed	Universal stress protein YxiE (USP YxiE)	yxiE BSU39250 N17E	Bacillus subtilis (strain 168)	148	response to stress [GO:0006950]	GO:0006950	0	0	0	PF00582;	2820	m.11060	126517.5	1692581	562901.6667	444647.3333	27671.66667	19255766.75	118501.3333	1829603.333	367406	24992483.78	16.31343885
CHOYP_LOC100180023.2.7	P42297	m.28766	sp	YXIE_BACSU	26.974	152	94	5	6	148	5	148	7.42E-09	54.3	YXIE_BACSU	reviewed	Universal stress protein YxiE (USP YxiE)	yxiE BSU39250 N17E	Bacillus subtilis (strain 168)	148	response to stress [GO:0006950]	GO:0006950	0	0	0	PF00582;	2821	m.28766	126517.5	1692581	562901.6667	444647.3333	27671.66667	19255766.75	118501.3333	1829603.333	367406	24992483.78	16.31343885
CHOYP_LOC100180023.4.7	Q2FXL6	m.33650	sp	Y1819_STAA8	30.303	165	85	5	15	177	7	143	7.54E-10	58.2	Y1819_STAA8	reviewed	Putative universal stress protein SAOUHSC_01819	SAOUHSC_01819	Staphylococcus aureus (strain NCTC 8325)	166	response to stress [GO:0006950]	GO:0005737; GO:0006950	0	0	0	PF00582;	2822	m.33650	NA	68444	120155	211663	63945	3433784.5	22435	99430	13806	863883	7.640278583
CHOYP_LOC100180023.5.7	A0QZA1	m.56825	sp	Y3950_MYCS2	28.571	154	94	4	4	153	10	151	4.48E-10	59.7	Y3950_MYCS2	reviewed	Universal stress protein MSMEG_3950/MSMEI_3859 (USP MSMEG_3950)	MSMEG_3950 MSMEI_3859	Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)	294	response to stress [GO:0006950]	GO:0006950	0	0	0	PF00582;	2823	m.56825	20097	103615	324919	NA	27665	NA	12744413	23790	20127.5	24708	26.9014195
CHOYP_LOC100180023.6.7	P74897	m.63800	sp	YQA3_THEAQ	40.26	77	36	1	76	142	61	137	3.77E-08	52	YQA3_THEAQ	reviewed	Universal stress protein in QAH/OAS sulfhydrylase 3'region (USP)	0	Thermus aquaticus	137	response to stress [GO:0006950]	GO:0006950	0	0	0	PF00582;	2824	m.63800	126517.5	1692581	562901.6667	444647.3333	27671.66667	19255766.75	118501.3333	1829603.333	367406	24992483.78	16.31343885
CHOYP_LOC100180855.1.4	Q2FXL6	m.29179	sp	Y1819_STAA8	33.813	139	87	4	15	150	7	143	7.12E-12	62.8	Y1819_STAA8	reviewed	Putative universal stress protein SAOUHSC_01819	SAOUHSC_01819	Staphylococcus aureus (strain NCTC 8325)	166	response to stress [GO:0006950]	GO:0005737; GO:0006950	0	0	0	PF00582;	2831	m.29179	NA	68444	120155	211663	63945	3433784.5	22435	99430	13806	863883	7.640278583
CHOYP_LOC100180855.2.4	Q8LGG8	m.46097	sp	USPAL_ARATH	28.261	138	87	5	14	141	27	162	2.22E-11	61.6	USPAL_ARATH	reviewed	Universal stress protein A-like protein	At3g01520 F4P13.7	Arabidopsis thaliana (Mouse-ear cress)	175	response to stress [GO:0006950]	GO:0005886; GO:0006950; GO:0016208	0	0	0	PF00582;	2832	m.46097	993920	202067.5	146146.5	298265	1299322.5	83000	1563098.333	370494	50451	321543	0.812521299
CHOYP_LOC100181607.1.2	O07552	m.36709	sp	NHAX_BACSU	33.333	81	54	0	113	193	86	166	1.96E-08	54.7	NHAX_BACSU	reviewed	Stress response protein NhaX	nhaX yheK BSU09690	Bacillus subtilis (strain 168)	166	response to stress [GO:0006950]	GO:0006950	0	0	0	PF00582;	2840	m.36709	494980	31084	64158.5	223025.3333	128777	205825.5	269893	22560	621286	133610.6667	1.330299502
CHOYP_LOC100181607.2.2	O07552	m.55285	sp	NHAX_BACSU	26.25	160	102	4	73	216	7	166	5.90E-09	56.6	NHAX_BACSU	reviewed	Stress response protein NhaX	nhaX yheK BSU09690	Bacillus subtilis (strain 168)	166	response to stress [GO:0006950]	GO:0006950	0	0	0	PF00582;	2841	m.55285	494980	31084	64158.5	223025.3333	128777	205825.5	269893	22560	621286	133610.6667	1.330299502
CHOYP_LOC100185549.1.6	Q8LGG8	m.31232	sp	USPAL_ARATH	27.465	142	90	4	37	166	19	159	9.07E-13	66.2	USPAL_ARATH	reviewed	Universal stress protein A-like protein	At3g01520 F4P13.7	Arabidopsis thaliana (Mouse-ear cress)	175	response to stress [GO:0006950]	GO:0005886; GO:0006950; GO:0016208	0	0	0	PF00582;	2853	m.31232	9392793.75	9362676.167	3288374.556	13621669.58	7987565.111	12743882.11	6355402.545	9557912.417	47197799.83	18264473	2.156078602
CHOYP_LOC100185549.3.6	Q8LGG8	m.43515	sp	USPAL_ARATH	28.169	142	89	4	21	150	19	159	5.99E-14	68.6	USPAL_ARATH	reviewed	Universal stress protein A-like protein	At3g01520 F4P13.7	Arabidopsis thaliana (Mouse-ear cress)	175	response to stress [GO:0006950]	GO:0005886; GO:0006950; GO:0016208	0	0	0	PF00582;	2854	m.43515	9392793.75	9362676.167	3288374.556	13621669.58	7987565.111	12743882.11	6355402.545	9557912.417	47197799.83	18264473	2.156078602
CHOYP_LOC100185549.4.6	Q8LGG8	m.57314	sp	USPAL_ARATH	28.244	131	84	3	17	138	30	159	1.07E-13	67.8	USPAL_ARATH	reviewed	Universal stress protein A-like protein	At3g01520 F4P13.7	Arabidopsis thaliana (Mouse-ear cress)	175	response to stress [GO:0006950]	GO:0005886; GO:0006950; GO:0016208	0	0	0	PF00582;	2855	m.57314	9392793.75	9362676.167	3288374.556	13621669.58	7987565.111	12743882.11	6355402.545	9557912.417	47197799.83	18264473	2.156078602
CHOYP_LOC100185549.5.6	Q57951	m.62694	sp	Y531_METJA	36.054	147	80	4	6	145	27	166	4.19E-12	63.5	Y531_METJA	reviewed	Universal stress protein MJ0531 (USP MJ0531)	MJ0531	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)	170	response to stress [GO:0006950]	GO:0006950	0	0	0	PF00582;	2856	m.62694	1012106	475406	55403	106649.5	129889	8840874	337367.4	166193	456820	34690.66667	5.527508905
CHOYP_LOC100185549.6.6	Q8LGG8	m.63147	sp	USPAL_ARATH	25.49	153	95	4	4	138	8	159	1.21E-12	65.1	USPAL_ARATH	reviewed	Universal stress protein A-like protein	At3g01520 F4P13.7	Arabidopsis thaliana (Mouse-ear cress)	175	response to stress [GO:0006950]	GO:0005886; GO:0006950; GO:0016208	0	0	0	PF00582;	2857	m.63147	9392793.75	9362676.167	3288374.556	13621669.58	7987565.111	12743882.11	6355402.545	9557912.417	47197799.83	18264473	2.156078602
CHOYP_LOC100211409.1.1	P04792	m.4742	sp	HSPB1_HUMAN	38.667	75	43	2	161	233	95	168	3.82E-10	60.8	HSPB1_HUMAN	reviewed	Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27)	HSPB1 HSP27 HSP28	Homo sapiens (Human)	205	cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028	0	0	0	PF00011;	2894	m.4742	651414.5556	337618.1	6317623.786	378199.4438	467184	338760.75	3826765.727	2681237.5	1244984.25	2706129.875	1.324561491
CHOYP_LOC100211409.1.1	P04792	m.4743	sp	HSPB1_HUMAN	32.099	81	54	1	46	125	89	169	1.88E-06	50.1	HSPB1_HUMAN	reviewed	Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27)	HSPB1 HSP27 HSP28	Homo sapiens (Human)	205	cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028	0	0	0	PF00011;	2894	m.4742	651414.5556	337618.1	6317623.786	378199.4438	467184	338760.75	3826765.727	2681237.5	1244984.25	2706129.875	1.324561491
CHOYP_LOC100367736.2.2	P20072	m.66862	sp	ANXA7_BOVIN	57.235	311	133	0	4	314	153	463	2.41E-129	379	ANXA7_BOVIN	reviewed	Annexin A7 (Annexin VII) (Annexin-7) (Synexin)	ANXA7 ANX7	Bos taurus (Bovine)	463	autophagy [GO:0006914]; cell proliferation [GO:0008283]; cellular calcium ion homeostasis [GO:0006874]; cellular water homeostasis [GO:0009992]; epithelial cell differentiation [GO:0030855]; hemostasis [GO:0007599]; negative regulation of gene expression [GO:0010629]; regulation of cell shape [GO:0008360]; response to salt stress [GO:0009651]; social behavior [GO:0035176]	GO:0005509; GO:0005544; GO:0005635; GO:0005789; GO:0005829; GO:0005886; GO:0006874; GO:0006914; GO:0007599; GO:0008283; GO:0008360; GO:0009651; GO:0009992; GO:0010629; GO:0030855; GO:0035176; GO:0042584; GO:0042802; GO:0044822; GO:0048306; GO:0070062	0	0	0	PF00191;	3035	m.66862	42641.5	126873	867329	84070.2	62815.25	599296.25	588864.5	578690.5	2222453.667	431413.8333	3.734570106
CHOYP_LOC100367895.1.1	P50093	m.23456	sp	PHB2_CAEEL	24.701	251	141	10	34	263	44	267	6.21E-06	50.4	PHB2_CAEEL	reviewed	Mitochondrial prohibitin complex protein 2 (Prohibitin-2)	phb-2 T24H7.1	Caenorhabditis elegans	294	defecation [GO:0030421]; embryo development ending in birth or egg hatching [GO:0009792]; gonad development [GO:0008406]; mitochondrion morphogenesis [GO:0070584]; oogenesis [GO:0048477]; positive regulation of multicellular organism growth [GO:0040018]; regulation of oxidative phosphorylation [GO:0002082]; regulation of pharyngeal pumping [GO:0043051]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	GO:0002082; GO:0005739; GO:0006979; GO:0007283; GO:0008406; GO:0009792; GO:0016021; GO:0030421; GO:0031966; GO:0035632; GO:0040018; GO:0043051; GO:0048477; GO:0070584	0	0	cd03401;	PF01145;	3042	m.23456	112635	56659	60334	128253	17742	114799	79891	33512	59806	134150	1.123887515
CHOYP_LOC100368486.1.1	O95433	m.18263	sp	AHSA1_HUMAN	44.058	345	186	3	1	345	1	338	1.20E-106	318	AHSA1_HUMAN	reviewed	Activator of 90 kDa heat shock protein ATPase homolog 1 (AHA1) (p38)	AHSA1 C14orf3 HSPC322	Homo sapiens (Human)	338	response to stress [GO:0006950]	GO:0001671; GO:0005737; GO:0005783; GO:0005829; GO:0005913; GO:0006950; GO:0051087; GO:0070062; GO:0098641	0	0	0	PF09229;PF08327;	3067	m.18263	215968.5714	268639.4	1098960	318909.8889	85470.4	599456.6667	113610	145458.375	1112724.889	199669.5	1.092040208
CHOYP_LOC100370583.1.1	Q05655	m.56859	sp	KPCD_HUMAN	53.21	701	284	8	6	694	4	672	0	766	KPCD_HUMAN	reviewed	Protein kinase C delta type (EC 2.7.11.13) (Tyrosine-protein kinase PRKCD) (EC 2.7.10.2) (nPKC-delta) [Cleaved into: Protein kinase C delta type regulatory subunit; Protein kinase C delta type catalytic subunit (Sphingosine-dependent protein kinase-1) (SDK1)]	PRKCD	Homo sapiens (Human)	676	activation of phospholipase C activity [GO:0007202]; activation of protein kinase activity [GO:0032147]; apoptotic process [GO:0006915]; B cell proliferation [GO:0042100]; cell chemotaxis [GO:0060326]; cell cycle [GO:0007049]; cellular component disassembly involved in execution phase of apoptosis [GO:0006921]; cellular response to angiotensin [GO:1904385]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hydroperoxide [GO:0071447]; cellular senescence [GO:0090398]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; histone phosphorylation [GO:0016572]; immunoglobulin mediated immune response [GO:0016064]; interferon-gamma-mediated signaling pathway [GO:0060333]; interleukin-10 production [GO:0032613]; interleukin-12 production [GO:0032615]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of filopodium assembly [GO:0051490]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of inflammatory response [GO:0050728]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of peptidyl-tyrosine phosphorylation [GO:0050732]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of protein binding [GO:0032091]; neutrophil activation [GO:0042119]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; platelet activation [GO:0030168]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of endodeoxyribonuclease activity [GO:0032079]; positive regulation of glucosylceramide catabolic process [GO:2000753]; positive regulation of phospholipid scramblase activity [GO:1900163]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of response to DNA damage stimulus [GO:2001022]; positive regulation of sphingomyelin catabolic process [GO:2000755]; positive regulation of superoxide anion generation [GO:0032930]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of mRNA stability [GO:0043488]; regulation of receptor activity [GO:0010469]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; termination of signal transduction [GO:0023021]	GO:0002223; GO:0004672; GO:0004674; GO:0004697; GO:0004699; GO:0004715; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005783; GO:0005829; GO:0005886; GO:0005911; GO:0006468; GO:0006915; GO:0006921; GO:0007049; GO:0007165; GO:0007202; GO:0008047; GO:0008631; GO:0010469; GO:0016064; GO:0016363; GO:0016572; GO:0018105; GO:0018107; GO:0019899; GO:0019900; GO:0019901; GO:0023021; GO:0030168; GO:0030837; GO:0032079; GO:0032091; GO:0032147; GO:0032613; GO:0032615; GO:0032930; GO:0032956; GO:0034351; GO:0035307; GO:0038096; GO:0042100; GO:0042119; GO:0042307; GO:0042742; GO:0043407; GO:0043488; GO:0043560; GO:0046627; GO:0046872; GO:0048471; GO:0050728; GO:0050732; GO:0050821; GO:0051490; GO:0060326; GO:0060333; GO:0070062; GO:0070301; GO:0071447; GO:0090331; GO:0090398; GO:1900163; GO:1904385; GO:2000304; GO:2000753; GO:2000755; GO:2001022; GO:2001235	0	0	0	PF00130;PF00069;PF00433;	3164	m.56859	321777.6667	215576.6667	401597.4	194346	93448.5	234549.25	155251.6667	1368883.4	1146157.333	1458051	3.556475277
CHOYP_LOC100371043.4.5	P00184	m.34262	sp	CP1A1_MOUSE	25.688	109	80	1	10	118	178	285	1.49E-06	49.3	CP1A1_MOUSE	reviewed	Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) (Cytochrome P450-P1)	Cyp1a1 Cyp1a-1	Mus musculus (Mouse)	524	9-cis-retinoic acid biosynthetic process [GO:0042904]; aging [GO:0007568]; amine metabolic process [GO:0009308]; camera-type eye development [GO:0043010]; cell proliferation [GO:0008283]; cellular response to organic cyclic compound [GO:0071407]; coumarin metabolic process [GO:0009804]; digestive tract development [GO:0048565]; drug metabolic process [GO:0017144]; embryo development ending in birth or egg hatching [GO:0009792]; flavonoid metabolic process [GO:0009812]; hepatocyte differentiation [GO:0070365]; heterocycle metabolic process [GO:0046483]; hydrogen peroxide biosynthetic process [GO:0050665]; insecticide metabolic process [GO:0017143]; maternal process involved in parturition [GO:0060137]; oxidation-reduction process [GO:0055114]; porphyrin-containing compound metabolic process [GO:0006778]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; response to antibiotic [GO:0046677]; response to arsenic-containing substance [GO:0046685]; response to drug [GO:0042493]; response to food [GO:0032094]; response to herbicide [GO:0009635]; response to hyperoxia [GO:0055093]; response to hypoxia [GO:0001666]; response to immobilization stress [GO:0035902]; response to iron(III) ion [GO:0010041]; response to lipopolysaccharide [GO:0032496]; response to nematode [GO:0009624]; response to toxic substance [GO:0009636]; response to virus [GO:0009615]; response to vitamin A [GO:0033189]; response to wounding [GO:0009611]; toxin metabolic process [GO:0009404]	GO:0001666; GO:0004497; GO:0005506; GO:0005739; GO:0005789; GO:0006778; GO:0007568; GO:0008283; GO:0008395; GO:0009308; GO:0009404; GO:0009611; GO:0009615; GO:0009624; GO:0009635; GO:0009636; GO:0009792; GO:0009804; GO:0009812; GO:0010041; GO:0016491; GO:0016679; GO:0016711; GO:0016712; GO:0017143; GO:0017144; GO:0020037; GO:0031090; GO:0032094; GO:0032451; GO:0032496; GO:0033189; GO:0035902; GO:0042493; GO:0042904; GO:0043010; GO:0043231; GO:0046483; GO:0046677; GO:0046685; GO:0048565; GO:0050665; GO:0055093; GO:0055114; GO:0060137; GO:0070330; GO:0070365; GO:0070576; GO:0071407; GO:1900087	0	0	0	PF00067;	3191	m.34263	186407	54401	1397167	260581.6667	22764.5	44155.5	298899.5	131393	65384.5	302437	0.438380378
CHOYP_LOC100371390.1.1	Q99700	m.8047	sp	ATX2_HUMAN	47.244	254	118	6	32	280	257	499	2.21E-66	245	ATX2_HUMAN	reviewed	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein)	ATXN2 ATX2 SCA2 TNRC13	Homo sapiens (Human)	1313	cytoplasmic mRNA processing body assembly [GO:0033962]; negative regulation of receptor internalization [GO:0002091]; regulation of cytoplasmic mRNA processing body assembly [GO:0010603]; regulation of translation [GO:0006417]; RNA metabolic process [GO:0016070]; RNA transport [GO:0050658]; stress granule assembly [GO:0034063]	GO:0002091; GO:0003723; GO:0005154; GO:0005654; GO:0005737; GO:0005794; GO:0005802; GO:0005844; GO:0006417; GO:0008022; GO:0010494; GO:0010603; GO:0016020; GO:0016070; GO:0030529; GO:0033962; GO:0034063; GO:0044822; GO:0048471; GO:0050658	0	0	0	PF06741;PF07145;PF14438;	3211	m.8047	159706.6	1062344.125	514401.2	72990.5	2158038.2	257529.8	186861.3333	70318.6	105033.5	248554.25	0.218853617
CHOYP_LOC100371808.1.2	P56597	m.15364	sp	NDK5_HUMAN	63.871	155	56	0	2	156	24	178	5.67E-76	229	NDK5_HUMAN	reviewed	Nucleoside diphosphate kinase homolog 5 (NDK-H 5) (NDP kinase homolog 5) (Inhibitor of p53-induced apoptosis-beta) (IPIA-beta) (Testis-specific nm23 homolog) (nm23-H5)	NME5	Homo sapiens (Human)	212	cilium assembly [GO:0042384]; CTP biosynthetic process [GO:0006241]; epithelial cilium movement [GO:0003351]; GTP biosynthetic process [GO:0006183]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; nucleoside metabolic process [GO:0009116]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]; UTP biosynthetic process [GO:0006228]; ventricular system development [GO:0021591]	GO:0003351; GO:0004550; GO:0005622; GO:0006183; GO:0006228; GO:0006241; GO:0007283; GO:0007286; GO:0009116; GO:0021591; GO:0036126; GO:0042384; GO:1902176	0	0	0	PF05186;PF00334;	3227	m.15364	288598.5	29334	192991	650690	71418	159705	153020	1577694	598702	3769738.143	5.075992903
CHOYP_LOC100371808.2.2	P56597	m.62772	sp	NDK5_HUMAN	65.934	182	62	0	24	205	4	185	1.39E-93	276	NDK5_HUMAN	reviewed	Nucleoside diphosphate kinase homolog 5 (NDK-H 5) (NDP kinase homolog 5) (Inhibitor of p53-induced apoptosis-beta) (IPIA-beta) (Testis-specific nm23 homolog) (nm23-H5)	NME5	Homo sapiens (Human)	212	cilium assembly [GO:0042384]; CTP biosynthetic process [GO:0006241]; epithelial cilium movement [GO:0003351]; GTP biosynthetic process [GO:0006183]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; nucleoside metabolic process [GO:0009116]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]; UTP biosynthetic process [GO:0006228]; ventricular system development [GO:0021591]	GO:0003351; GO:0004550; GO:0005622; GO:0006183; GO:0006228; GO:0006241; GO:0007283; GO:0007286; GO:0009116; GO:0021591; GO:0036126; GO:0042384; GO:1902176	0	0	0	PF05186;PF00334;	3228	m.62772	288598.5	29334	192991	650690	71418	159705	153020	1577694	598702	3769738.143	5.075992903
CHOYP_LOC100372340.1.3	Q921X9	m.9116	sp	PDIA5_MOUSE	44.489	499	258	8	43	527	7	500	2.40E-138	421	PDIA5_MOUSE	reviewed	Protein disulfide-isomerase A5 (EC 5.3.4.1) (Protein disulfide isomerase-related protein)	Pdia5 Pdir	Mus musculus (Mouse)	517	cell redox homeostasis [GO:0045454]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976]	GO:0003756; GO:0005783; GO:0005788; GO:0006457; GO:0034976; GO:0045454	0	0	0	PF00085;	3258	m.9116	1464705.545	396121.5	15340154	760174.4118	989724.7143	1619323.929	306404.4167	235856.2308	1442006.438	497221.1333	0.216391646
CHOYP_LOC100372340.2.3	Q921X9	m.43098	sp	PDIA5_MOUSE	44.012	334	174	7	1	328	174	500	6.81E-80	263	PDIA5_MOUSE	reviewed	Protein disulfide-isomerase A5 (EC 5.3.4.1) (Protein disulfide isomerase-related protein)	Pdia5 Pdir	Mus musculus (Mouse)	517	cell redox homeostasis [GO:0045454]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976]	GO:0003756; GO:0005783; GO:0005788; GO:0006457; GO:0034976; GO:0045454	0	0	0	PF00085;	3259	m.43098	1750104.333	454950.25	31951496.8	755199.0833	1039476.273	1796544.571	73879.7	180075	1479535.538	107414.5	0.101177335
CHOYP_LOC100372340.3.3	Q921X9	m.59986	sp	PDIA5_MOUSE	39.645	338	182	10	15	346	180	501	2.60E-63	213	PDIA5_MOUSE	reviewed	Protein disulfide-isomerase A5 (EC 5.3.4.1) (Protein disulfide isomerase-related protein)	Pdia5 Pdir	Mus musculus (Mouse)	517	cell redox homeostasis [GO:0045454]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976]	GO:0003756; GO:0005783; GO:0005788; GO:0006457; GO:0034976; GO:0045454	0	0	0	PF00085;	3260	m.59986	2541475	767105	34330258	1356874.5	2074228.2	2807007.25	33866.5	176272.4	1998023.714	48818.25	0.123301569
CHOYP_LOC100372481.1.1	P23727	m.21010	sp	P85A_BOVIN	38.599	614	329	15	346	933	128	719	8.43E-108	353	P85A_BOVIN	reviewed	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)	PIK3R1	Bos taurus (Bovine)	724	B cell differentiation [GO:0030183]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to UV [GO:0034644]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; growth hormone receptor signaling pathway [GO:0060396]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin receptor signaling pathway [GO:0008286]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of osteoclast differentiation [GO:0045671]; NFAT protein import into nucleus [GO:0051531]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol phosphorylation [GO:0046854]; positive regulation of cell migration [GO:0030335]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; positive regulation of glucose import [GO:0046326]; positive regulation of glucose import in response to insulin stimulus [GO:2001275]; positive regulation of RNA splicing [GO:0033120]; positive regulation of transcription factor import into nucleus [GO:0042993]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551]; regulation of stress fiber assembly [GO:0051492]; response to endoplasmic reticulum stress [GO:0034976]	GO:0001678; GO:0001953; GO:0005068; GO:0005158; GO:0005159; GO:0005634; GO:0005801; GO:0005829; GO:0005911; GO:0005942; GO:0005943; GO:0006468; GO:0008286; GO:0008625; GO:0008630; GO:0014065; GO:0030183; GO:0030335; GO:0032760; GO:0032869; GO:0033120; GO:0034644; GO:0034976; GO:0035014; GO:0042993; GO:0043066; GO:0043125; GO:0043548; GO:0043551; GO:0043560; GO:0045671; GO:0045944; GO:0046326; GO:0046854; GO:0046935; GO:0048009; GO:0050821; GO:0051492; GO:0051531; GO:0060396; GO:0090004; GO:1900103; GO:1990578; GO:2001275	0	0	0	PF16454;PF00620;PF00017;	3269	m.21010	180058	19924	1161900.25	449807.5	1019180	15944	37838	1482794	224607	428211.5	0.773399942
CHOYP_LOC100372481.1.1	P23727	m.21010	sp	P85A_BOVIN	38.599	614	329	15	346	933	128	719	8.43E-108	353	P85A_BOVIN	reviewed	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)	PIK3R1	Bos taurus (Bovine)	724	B cell differentiation [GO:0030183]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to UV [GO:0034644]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; growth hormone receptor signaling pathway [GO:0060396]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin receptor signaling pathway [GO:0008286]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of osteoclast differentiation [GO:0045671]; NFAT protein import into nucleus [GO:0051531]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol phosphorylation [GO:0046854]; positive regulation of cell migration [GO:0030335]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; positive regulation of glucose import [GO:0046326]; positive regulation of glucose import in response to insulin stimulus [GO:2001275]; positive regulation of RNA splicing [GO:0033120]; positive regulation of transcription factor import into nucleus [GO:0042993]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551]; regulation of stress fiber assembly [GO:0051492]; response to endoplasmic reticulum stress [GO:0034976]	GO:0001678; GO:0001953; GO:0005068; GO:0005158; GO:0005159; GO:0005634; GO:0005801; GO:0005829; GO:0005911; GO:0005942; GO:0005943; GO:0006468; GO:0008286; GO:0008625; GO:0008630; GO:0014065; GO:0030183; GO:0030335; GO:0032760; GO:0032869; GO:0033120; GO:0034644; GO:0034976; GO:0035014; GO:0042993; GO:0043066; GO:0043125; GO:0043548; GO:0043551; GO:0043560; GO:0045671; GO:0045944; GO:0046326; GO:0046854; GO:0046935; GO:0048009; GO:0050821; GO:0051492; GO:0051531; GO:0060396; GO:0090004; GO:1900103; GO:1990578; GO:2001275	0	0	0	PF16454;PF00620;PF00017;	3270	m.21011	711415.6667	1232484.667	5839820.4	996151.5	894481.75	970698.75	2548209.8	2881977.667	75299.33333	1651054.25	0.840080879
CHOYP_LOC100373694.1.1	P0CB97	m.11753	sp	NDUS8_PONAB	76.882	186	43	0	38	223	25	210	1.25E-103	301	NDUS8_PONAB	reviewed	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3) (Complex I-23kD) (CI-23kD) (NADH-ubiquinone oxidoreductase 23 kDa subunit)"	NDUFS8	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	210	mitochondrial respiratory chain complex I assembly [GO:0032981]; response to oxidative stress [GO:0006979]	GO:0005739; GO:0005747; GO:0006979; GO:0008137; GO:0032981; GO:0046872; GO:0051539	0	0	0	PF12838;	3367	m.11753	614771	390877	243589	131818.5	76238	NA	146470	330137	168836	342798.5	0.847668555
CHOYP_LOC100373864.2.2	O08605	m.55131	sp	MKNK1_MOUSE	56.345	394	148	5	71	460	35	408	4.52E-152	443	MKNK1_MOUSE	reviewed	MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (MAPK signal-integrating kinase 1) (Mnk1)	Mknk1 Mnk1	Mus musculus (Mouse)	427	extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of translation [GO:0006417]; response to salt stress [GO:0009651]	GO:0004674; GO:0004683; GO:0005516; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0006417; GO:0006468; GO:0009651; GO:0009931; GO:0018105; GO:0035556; GO:0046777; GO:0097192	0	0	0	PF00069;	3374	m.55132	3677122	1123913	4446058.5	51969	261188.5	21725000.67	1910958.75	3580302	402219	323378	2.922711801
CHOYP_LOC100373888.9.9	P29590	m.66033	sp	PML_HUMAN	25.51	392	233	15	54	420	31	388	6.95E-18	92	PML_HUMAN	reviewed	Protein PML (Promyelocytic leukemia protein) (RING finger protein 71) (Tripartite motif-containing protein 19)	PML MYL PP8675 RNF71 TRIM19	Homo sapiens (Human)	882	"activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell cycle arrest [GO:0007050]; cell fate commitment [GO:0045165]; cellular response to interleukin-4 [GO:0071353]; cellular senescence [GO:0090398]; circadian regulation of gene expression [GO:0032922]; common-partner SMAD protein phosphorylation [GO:0007182]; defense response to virus [GO:0051607]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endoplasmic reticulum calcium ion homeostasis [GO:0032469]; entrainment of circadian clock by photoperiod [GO:0043153]; extrinsic apoptotic signaling pathway [GO:0097191]; fibroblast migration [GO:0010761]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; maintenance of protein location in nucleus [GO:0051457]; myeloid cell differentiation [GO:0030099]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell growth [GO:0030308]; negative regulation of cell proliferation [GO:0008285]; negative regulation of interleukin-1 beta secretion [GO:0050713]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:2000059]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of translation in response to oxidative stress [GO:0032938]; negative regulation of viral release from host cell [GO:1902187]; PML body organization [GO:0030578]; positive regulation of apoptotic process involved in mammary gland involution [GO:0060058]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of protein localization to chromosome, telomeric region [GO:1904816]; positive regulation of telomere maintenance [GO:0032206]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein complex assembly [GO:0006461]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; protein targeting [GO:0006605]; regulation of calcium ion transport into cytosol [GO:0010522]; regulation of cell adhesion [GO:0030155]; regulation of circadian rhythm [GO:0042752]; regulation of double-strand break repair [GO:2000779]; regulation of MHC class I biosynthetic process [GO:0045343]; regulation of protein phosphorylation [GO:0001932]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription, DNA-templated [GO:0006355]; response to cytokine [GO:0034097]; response to gamma radiation [GO:0010332]; response to hypoxia [GO:0001666]; response to UV [GO:0009411]; retinoic acid receptor signaling pathway [GO:0048384]; SMAD protein import into nucleus [GO:0007184]; transcription, DNA-templated [GO:0006351]; transforming growth factor beta receptor signaling pathway [GO:0007179]"	GO:0000784; GO:0001666; GO:0001932; GO:0002230; GO:0003677; GO:0003713; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0006351; GO:0006355; GO:0006461; GO:0006605; GO:0006915; GO:0006919; GO:0006977; GO:0007050; GO:0007179; GO:0007182; GO:0007184; GO:0008270; GO:0008285; GO:0008630; GO:0008631; GO:0009411; GO:0010332; GO:0010522; GO:0010761; GO:0016363; GO:0016525; GO:0016605; GO:0016925; GO:0030099; GO:0030155; GO:0030308; GO:0030578; GO:0031065; GO:0031625; GO:0031901; GO:0031965; GO:0032183; GO:0032206; GO:0032211; GO:0032469; GO:0032922; GO:0032938; GO:0034097; GO:0042406; GO:0042752; GO:0042771; GO:0042803; GO:0043153; GO:0043161; GO:0045087; GO:0045165; GO:0045343; GO:0045892; GO:0045930; GO:0046982; GO:0048146; GO:0048384; GO:0050713; GO:0050821; GO:0050897; GO:0051457; GO:0051607; GO:0051974; GO:0060058; GO:0060333; GO:0060444; GO:0070059; GO:0071353; GO:0090398; GO:0097191; GO:1901796; GO:1902187; GO:1904816; GO:2000059; GO:2000779; GO:2001238	0	0	0	PF12126;PF00643;	3376	m.66033	40813	36983	755180	29621	29284	39954	35112	38534	3508465	20899	4.084585275
CHOYP_LOC100374573.1.1	P31689	m.24523	sp	DNJA1_HUMAN	65.594	404	125	5	1	398	1	396	4.75E-179	506	DNJA1_HUMAN	reviewed	DnaJ homolog subfamily A member 1 (DnaJ protein homolog 2) (HSDJ) (Heat shock 40 kDa protein 4) (Heat shock protein J2) (HSJ-2) (Human DnaJ protein 2) (hDj-2)	DNAJA1 DNAJ2 HDJ2 HSJ2 HSPF4	Homo sapiens (Human)	397	"androgen receptor signaling pathway [GO:0030521]; DNA damage response, detection of DNA damage [GO:0042769]; negative regulation of apoptotic process [GO:0043066]; negative regulation of establishment of protein localization to mitochondrion [GO:1903748]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway [GO:1905259]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of apoptotic process [GO:0043065]; protein folding [GO:0006457]; protein localization to mitochondrion [GO:0070585]; regulation of protein transport [GO:0051223]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; spermatogenesis [GO:0007283]; sperm motility [GO:0030317]; toxin transport [GO:1901998]"	GO:0001664; GO:0005524; GO:0005634; GO:0005739; GO:0005829; GO:0006457; GO:0006986; GO:0007283; GO:0009408; GO:0016020; GO:0030317; GO:0030521; GO:0030544; GO:0030957; GO:0031397; GO:0031625; GO:0042769; GO:0043065; GO:0043066; GO:0043508; GO:0046872; GO:0048471; GO:0050750; GO:0051087; GO:0051223; GO:0055131; GO:0070062; GO:0070585; GO:0098554; GO:1901998; GO:1903748; GO:1905259	0	0	cd06257;	PF00226;PF01556;PF00684;	3405	m.24523	309802.2	353796.6667	79159	386589.25	1288476.2	1920633.333	342487	276688	117232	4563791.667	2.986501102
CHOYP_LOC100377173.1.2	P04792	m.37699	sp	HSPB1_HUMAN	38.667	75	43	2	161	233	95	168	1.68E-09	59.3	HSPB1_HUMAN	reviewed	Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27)	HSPB1 HSP27 HSP28	Homo sapiens (Human)	205	cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028	0	0	0	PF00011;	3596	m.37698	2755969.8	72264.1	698586.8667	685428.0769	198614.6667	379931.6667	524564.4615	294265.0833	1047699.833	1460404.467	0.840394518
CHOYP_LOC100377173.1.2	P04792	m.37699	sp	HSPB1_HUMAN	38.667	75	43	2	161	233	95	168	1.68E-09	59.3	HSPB1_HUMAN	reviewed	Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27)	HSPB1 HSP27 HSP28	Homo sapiens (Human)	205	cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028	0	0	0	PF00011;	3597	m.37699	651414.5556	337618.1	6317623.786	378199.4438	467184	338760.75	3826765.727	2681237.5	1244984.25	2706129.875	1.324561491
CHOYP_LOC100377729.1.1	Q8IW41	m.51881	sp	MAPK5_HUMAN	49.785	466	208	8	13	461	11	467	1.24E-157	458	MAPK5_HUMAN	reviewed	MAP kinase-activated protein kinase 5 (MAPK-activated protein kinase 5) (MAPKAP kinase 5) (MAPKAP-K5) (MAPKAPK-5) (MK-5) (MK5) (EC 2.7.11.1) (p38-regulated/activated protein kinase) (PRAK)	MAPKAPK5 PRAK	Homo sapiens (Human)	473	negative regulation of TOR signaling [GO:0032007]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein autophosphorylation [GO:0046777]; Ras protein signal transduction [GO:0007265]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of translation [GO:0006417]; signal transduction [GO:0007165]; stress-induced premature senescence [GO:0090400]	GO:0002039; GO:0004674; GO:0004683; GO:0004708; GO:0005516; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006417; GO:0007165; GO:0007265; GO:0009931; GO:0018105; GO:0032007; GO:0032212; GO:0046777; GO:0051973; GO:0090400; GO:1901796; GO:1904355	0	0	0	PF00069;	3629	m.51881	29695	1215179	8862562.5	66663	1413225	937073.3333	918326	298571	3442730	2221973	0.674760885
CHOYP_LOC100377736.1.1	P97478	m.251	sp	COQ7_MOUSE	65.909	176	60	0	20	195	42	217	2.59E-84	251	COQ7_MOUSE	reviewed	"5-demethoxyubiquinone hydroxylase, mitochondrial (DMQ hydroxylase) (EC 1.14.13.-) (Timing protein clk-1 homolog) (Ubiquinone biosynthesis monooxygenase COQ7)"	Coq7	Mus musculus (Mouse)	217	age-dependent response to oxidative stress [GO:0001306]; cellular response to oxidative stress [GO:0034599]; determination of adult lifespan [GO:0008340]; in utero embryonic development [GO:0001701]; mitochondrial ATP synthesis coupled electron transport [GO:0042775]; mitochondrion morphogenesis [GO:0070584]; neural tube formation [GO:0001841]; neurogenesis [GO:0022008]; respiratory electron transport chain [GO:0022904]; response to oxidative stress [GO:0006979]; ubiquinone biosynthetic process [GO:0006744]	GO:0001306; GO:0001701; GO:0001841; GO:0005634; GO:0005739; GO:0006744; GO:0006979; GO:0008340; GO:0016709; GO:0022008; GO:0022904; GO:0031314; GO:0034599; GO:0042775; GO:0046872; GO:0070584	PATHWAY: Cofactor biosynthesis; ubiquinone biosynthesis. {ECO:0000255|HAMAP-Rule:MF_03194}.	0	cd01042;	PF03232;	3630	m.251	9629044.286	2157134.333	151862407	40043782.5	437049.4	9288755.75	20225328.4	17160025.17	28197127.5	4312613.8	0.387910041
CHOYP_LOC100533387.1.1	P62325	m.56132	sp	BTG1_MOUSE	47.205	161	80	2	1	156	11	171	2.18E-47	155	BTG1_MOUSE	reviewed	Protein BTG1 (B-cell translocation gene 1 protein)	Btg1	Mus musculus (Mouse)	171	negative regulation of cell proliferation [GO:0008285]; positive regulation of angiogenesis [GO:0045766]; positive regulation of catalytic activity [GO:0043085]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of fibroblast apoptotic process [GO:2000271]; positive regulation of myoblast differentiation [GO:0045663]; protein methylation [GO:0006479]; response to oxidative stress [GO:0006979]; response to peptide hormone [GO:0043434]; spermatogenesis [GO:0007283]	GO:0005634; GO:0005737; GO:0006479; GO:0006979; GO:0007283; GO:0008285; GO:0019899; GO:0043085; GO:0043434; GO:0045603; GO:0045663; GO:0045766; GO:2000271	0	0	0	PF07742;	3762	m.56131	2543439.769	822958.3333	1283052.381	844081.4815	1205274.6	1072833	262935.6	20953698.08	905398.1053	1884177.545	3.743807511
CHOYP_LOC100533447.2.3	O43639	m.44497	sp	NCK2_HUMAN	41.606	411	199	13	4	407	3	379	4.49E-96	295	NCK2_HUMAN	reviewed	Cytoplasmic protein NCK2 (Growth factor receptor-bound protein 4) (NCK adaptor protein 2) (Nck-2) (SH2/SH3 adaptor protein NCK-beta)	NCK2 GRB4	Homo sapiens (Human)	380	actin filament organization [GO:0007015]; cell migration [GO:0016477]; dendritic spine development [GO:0060996]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; immunological synapse formation [GO:0001771]; lamellipodium assembly [GO:0030032]; negative regulation of cell proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation [GO:1903912]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990441]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902237]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of translation in response to endoplasmic reticulum stress [GO:0036493]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vesicle-mediated transport [GO:0016192]	GO:0001771; GO:0005070; GO:0005086; GO:0005737; GO:0005783; GO:0005802; GO:0005829; GO:0007015; GO:0007165; GO:0007172; GO:0007173; GO:0007176; GO:0008093; GO:0008285; GO:0012506; GO:0016192; GO:0016477; GO:0030032; GO:0030159; GO:0030838; GO:0033137; GO:0036493; GO:0042102; GO:0042110; GO:0045202; GO:0045944; GO:0048010; GO:0048013; GO:0060996; GO:1902237; GO:1903898; GO:1903912; GO:1990441	0	0	0	PF00017;PF00018;PF14604;	3767	m.44496	10328782.03	497862.3913	3764196.654	12515428.81	9305536.231	10536600.91	12121259.5	7468543.938	2208347.545	7931059.577	1.105844938
CHOYP_LOC100561894.1.1	P20072	m.45814	sp	ANXA7_BOVIN	53.552	366	152	4	238	593	104	461	9.31E-131	394	ANXA7_BOVIN	reviewed	Annexin A7 (Annexin VII) (Annexin-7) (Synexin)	ANXA7 ANX7	Bos taurus (Bovine)	463	autophagy [GO:0006914]; cell proliferation [GO:0008283]; cellular calcium ion homeostasis [GO:0006874]; cellular water homeostasis [GO:0009992]; epithelial cell differentiation [GO:0030855]; hemostasis [GO:0007599]; negative regulation of gene expression [GO:0010629]; regulation of cell shape [GO:0008360]; response to salt stress [GO:0009651]; social behavior [GO:0035176]	GO:0005509; GO:0005544; GO:0005635; GO:0005789; GO:0005829; GO:0005886; GO:0006874; GO:0006914; GO:0007599; GO:0008283; GO:0008360; GO:0009651; GO:0009992; GO:0010629; GO:0030855; GO:0035176; GO:0042584; GO:0042802; GO:0044822; GO:0048306; GO:0070062	0	0	0	PF00191;	3808	m.45814	2674068.7	176396.5	64588.83333	183689.2857	87118.33333	1600141.444	100164.3333	83162.25	80778.71429	716540.9	0.81007524
CHOYP_LOC100561894.1.1	P20072	m.45814	sp	ANXA7_BOVIN	53.552	366	152	4	238	593	104	461	9.31E-131	394	ANXA7_BOVIN	reviewed	Annexin A7 (Annexin VII) (Annexin-7) (Synexin)	ANXA7 ANX7	Bos taurus (Bovine)	463	autophagy [GO:0006914]; cell proliferation [GO:0008283]; cellular calcium ion homeostasis [GO:0006874]; cellular water homeostasis [GO:0009992]; epithelial cell differentiation [GO:0030855]; hemostasis [GO:0007599]; negative regulation of gene expression [GO:0010629]; regulation of cell shape [GO:0008360]; response to salt stress [GO:0009651]; social behavior [GO:0035176]	GO:0005509; GO:0005544; GO:0005635; GO:0005789; GO:0005829; GO:0005886; GO:0006874; GO:0006914; GO:0007599; GO:0008283; GO:0008360; GO:0009651; GO:0009992; GO:0010629; GO:0030855; GO:0035176; GO:0042584; GO:0042802; GO:0044822; GO:0048306; GO:0070062	0	0	0	PF00191;	3809	m.45815	550612	NA	17870	313515.5	114234	16546	1237247	363960	1074780.5	47084	2.199984642
CHOYP_LOC100562954.1.1	O70309	m.27429	sp	ITB5_MOUSE	32.836	804	483	20	3	778	6	780	4.34E-152	467	ITB5_MOUSE	reviewed	Integrin beta-5	Itgb5	Mus musculus (Mouse)	798	cell-matrix adhesion [GO:0007160]; epithelial cell-cell adhesion [GO:0090136]; integrin-mediated signaling pathway [GO:0007229]; stress fiber assembly [GO:0043149]; transforming growth factor beta receptor signaling pathway [GO:0007179]	GO:0004872; GO:0005178; GO:0005886; GO:0005925; GO:0007160; GO:0007179; GO:0007229; GO:0009986; GO:0031252; GO:0034684; GO:0043149; GO:0043235; GO:0070062; GO:0090136	0	0	0	PF08725;PF07965;PF00362;	3811	m.27429	936189.8	387688.25	158992.2	226367.5	964465.5	759999.8	248347.6667	445229.5	1103245.4	1261770.286	1.428203617
CHOYP_LOC100638372.1.1	P97478	m.60469	sp	COQ7_MOUSE	66.092	174	59	0	20	193	42	215	2.02E-83	249	COQ7_MOUSE	reviewed	"5-demethoxyubiquinone hydroxylase, mitochondrial (DMQ hydroxylase) (EC 1.14.13.-) (Timing protein clk-1 homolog) (Ubiquinone biosynthesis monooxygenase COQ7)"	Coq7	Mus musculus (Mouse)	217	age-dependent response to oxidative stress [GO:0001306]; cellular response to oxidative stress [GO:0034599]; determination of adult lifespan [GO:0008340]; in utero embryonic development [GO:0001701]; mitochondrial ATP synthesis coupled electron transport [GO:0042775]; mitochondrion morphogenesis [GO:0070584]; neural tube formation [GO:0001841]; neurogenesis [GO:0022008]; respiratory electron transport chain [GO:0022904]; response to oxidative stress [GO:0006979]; ubiquinone biosynthetic process [GO:0006744]	GO:0001306; GO:0001701; GO:0001841; GO:0005634; GO:0005739; GO:0006744; GO:0006979; GO:0008340; GO:0016709; GO:0022008; GO:0022904; GO:0031314; GO:0034599; GO:0042775; GO:0046872; GO:0070584	PATHWAY: Cofactor biosynthesis; ubiquinone biosynthesis. {ECO:0000255|HAMAP-Rule:MF_03194}.	0	cd01042;	PF03232;	3849	m.60469	183480	292165	253051233.7	345996	76015	1553638	51530	157455	1019794	1694148	0.017627819
CHOYP_LOC100650469.1.2	Q9JM52	m.42139	sp	MINK1_MOUSE	77.174	368	68	2	7	374	9	360	0	573	MINK1_MOUSE	reviewed	Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (Mitogen-activated protein kinase kinase kinase kinase 6)	Mink1 Map4k6 Mink	Mus musculus (Mouse)	1308	actin cytoskeleton reorganization [GO:0031532]; chemical synaptic transmission [GO:0007268]; dendrite morphogenesis [GO:0048813]; intracellular signal transduction [GO:0035556]; multicellular organism development [GO:0007275]; negative thymic T cell selection [GO:0045060]; positive regulation of JNK cascade [GO:0046330]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity [GO:2000311]; regulation of cell-cell adhesion [GO:0022407]; regulation of cell-matrix adhesion [GO:0001952]; regulation of cell migration [GO:0030334]; response to stress [GO:0006950]	GO:0001952; GO:0004674; GO:0004702; GO:0005524; GO:0005737; GO:0005794; GO:0006468; GO:0006950; GO:0007268; GO:0007275; GO:0014069; GO:0022407; GO:0030054; GO:0030334; GO:0030424; GO:0030425; GO:0031532; GO:0035556; GO:0045060; GO:0045211; GO:0046330; GO:0046777; GO:0048813; GO:0070062; GO:2000311	0	0	0	PF00780;PF00069;	3882	m.42139	901641	1035336.333	251650	37681	535007	45542	752513	463726.5	1268428	543585	1.113163159
CHOYP_LOC100650469.2.2	Q9JM52	m.63001	sp	MINK1_MOUSE	80.453	353	68	1	7	359	9	360	0	583	MINK1_MOUSE	reviewed	Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (Mitogen-activated protein kinase kinase kinase kinase 6)	Mink1 Map4k6 Mink	Mus musculus (Mouse)	1308	actin cytoskeleton reorganization [GO:0031532]; chemical synaptic transmission [GO:0007268]; dendrite morphogenesis [GO:0048813]; intracellular signal transduction [GO:0035556]; multicellular organism development [GO:0007275]; negative thymic T cell selection [GO:0045060]; positive regulation of JNK cascade [GO:0046330]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity [GO:2000311]; regulation of cell-cell adhesion [GO:0022407]; regulation of cell-matrix adhesion [GO:0001952]; regulation of cell migration [GO:0030334]; response to stress [GO:0006950]	GO:0001952; GO:0004674; GO:0004702; GO:0005524; GO:0005737; GO:0005794; GO:0006468; GO:0006950; GO:0007268; GO:0007275; GO:0014069; GO:0022407; GO:0030054; GO:0030334; GO:0030424; GO:0030425; GO:0031532; GO:0035556; GO:0045060; GO:0045211; GO:0046330; GO:0046777; GO:0048813; GO:0070062; GO:2000311	0	0	0	PF00780;PF00069;	3883	m.63001	901641	1035336.333	251650	37681	535007	45542	752513	463726.5	1268428	543585	1.113163159
CHOYP_LOC100694623.1.1	Q8WY54	m.14876	sp	PPM1E_HUMAN	43.552	411	214	3	79	484	138	535	8.29E-108	352	PPM1E_HUMAN	reviewed	Protein phosphatase 1E (EC 3.1.3.16) (Ca(2+)/calmodulin-dependent protein kinase phosphatase N) (CaMKP-N) (CaMKP-nucleus) (CaMKN) (Partner of PIX 1) (Partner of PIX-alpha) (Partner of PIXA)	PPM1E CAMKN KIAA1072 POPX1	Homo sapiens (Human)	764	cellular response to drug [GO:0035690]; negative regulation of protein kinase activity [GO:0006469]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of stress fiber assembly [GO:0051496]	GO:0004722; GO:0005634; GO:0005730; GO:0005739; GO:0006469; GO:0035690; GO:0035970; GO:0043234; GO:0046872; GO:0051496	0	0	0	PF00481;	3905	m.14876	46495	107811.5	472147.6667	521644.75	1033410.2	42336	93152	2600712.5	715367	705021.6667	1.905373273
CHOYP_LOC100698842.1.1	Q08420	m.40947	sp	SODE_RAT	29.054	148	96	7	25	171	48	187	2.92E-09	57.8	SODE_RAT	reviewed	Extracellular superoxide dismutase [Cu-Zn] (EC-SOD) (EC 1.15.1.1) (Superoxide dismutase B)	Sod3 Sod-3	Rattus norvegicus (Rat)	244	response to copper ion [GO:0046688]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]; response to superoxide [GO:0000303]	GO:0000303; GO:0001666; GO:0004784; GO:0005507; GO:0005615; GO:0005634; GO:0005737; GO:0005802; GO:0006979; GO:0008270; GO:0031012; GO:0046688; GO:0070062	0	0	cd00305;	PF00080;	3928	m.40947	186559	208482	1126469.5	365970	206897.75	35060	79125	547840.3333	44132	51690	0.361848359
CHOYP_LOC100703866.1.2	Q8K4Q6	m.44331	sp	NEIL1_MOUSE	49.231	325	152	5	1	317	1	320	1.04E-103	315	NEIL1_MOUSE	reviewed	Endonuclease 8-like 1 (EC 3.2.2.-) (EC 4.2.99.18) (DNA glycosylase/AP lyase Neil1) (DNA-(apurinic or apyrimidinic site) lyase Neil1) (Endonuclease VIII-like 1) (Nei homolog 1) (NEH1) (Nei-like protein 1)	Neil1 Nei1	Mus musculus (Mouse)	389	base-excision repair [GO:0006284]; DNA repair [GO:0006281]; negative regulation of nuclease activity [GO:0032074]; nucleotide-excision repair [GO:0006289]; response to oxidative stress [GO:0006979]	GO:0003684; GO:0003906; GO:0005634; GO:0005694; GO:0005737; GO:0005815; GO:0006281; GO:0006284; GO:0006289; GO:0006979; GO:0008022; GO:0008270; GO:0016798; GO:0016829; GO:0019104; GO:0032074	0	0	0	PF01149;PF06831;PF09292;	3940	m.44330	612738.6667	90328311	159442182	146111.25	46292413.67	10210595.6	30487981.25	25471100.25	1754813.5	7664090.5	0.25465984
CHOYP_LOC100704237.1.2	Q96A56	m.6766	sp	T53I1_HUMAN	29.518	166	98	8	24	181	85	239	6.24E-07	51.2	T53I1_HUMAN	reviewed	Tumor protein p53-inducible nuclear protein 1 (Stress-induced protein) (p53-dependent damage-inducible nuclear protein 1) (p53DINP1)	TP53INP1 P53DINP1 SIP	Homo sapiens (Human)	240	"apoptotic process [GO:0006915]; autophagic cell death [GO:0048102]; autophagosome assembly [GO:0000045]; cell cycle arrest [GO:0007050]; cellular response to ethanol [GO:0071361]; cellular response to hydroperoxide [GO:0071447]; cellular response to methyl methanesulfonate [GO:0072703]; cellular response to UV [GO:0034644]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of autophagy [GO:0010508]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of apoptotic process [GO:0042981]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to heat [GO:0009408]; response to stress [GO:0006950]; transcription, DNA-templated [GO:0006351]"	GO:0000045; GO:0005634; GO:0005654; GO:0005737; GO:0005776; GO:0005829; GO:0006351; GO:0006915; GO:0006950; GO:0007050; GO:0008285; GO:0009408; GO:0010508; GO:0016209; GO:0016605; GO:0030336; GO:0031410; GO:0034644; GO:0042981; GO:0045893; GO:0048102; GO:0071361; GO:0071447; GO:0072703; GO:1901796; GO:2001235	0	0	0	PF14839;	3941	m.6768	507306	NA	171624	110176	46699	514788	56250	84206	151401	515857	1.265847417
CHOYP_LOC100706287.1.1	P10758	m.44791	sp	LITH_RAT	36.429	140	81	5	223	357	26	162	8.69E-21	91.3	LITH_RAT	reviewed	Lithostathine (Islet cells regeneration factor) (ICRF) (Islet of Langerhans regenerating protein) (REG) (Pancreatic stone protein) (PSP) (Pancreatic thread protein) (PTP)	Reg1 Reg	Rattus norvegicus (Rat)	165	calcium ion homeostasis [GO:0055074]; cellular response to chemokine [GO:1990869]; cellular response to gastrin [GO:1990878]; liver regeneration [GO:0097421]; midgut development [GO:0007494]; negative regulation of cell proliferation [GO:0008285]; pancreas regeneration [GO:1990798]; positive regulation of acinar cell proliferation [GO:1904699]; positive regulation of dendrite extension [GO:1903861]; positive regulation of gene expression [GO:0010628]; positive regulation of type B pancreatic cell proliferation [GO:1904692]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; response to acetylsalicylate [GO:1903492]; response to gastrin [GO:1990867]; response to growth hormone-releasing hormone [GO:1990864]; response to hypoxia [GO:0001666]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; response to water-immersion restraint stress [GO:1990785]; wound healing [GO:0042060]	GO:0001666; GO:0005102; GO:0005615; GO:0005829; GO:0007494; GO:0008083; GO:0008285; GO:0010628; GO:0014070; GO:0019902; GO:0019903; GO:0030246; GO:0030426; GO:0031667; GO:0032590; GO:0032809; GO:0042060; GO:0042588; GO:0042802; GO:0042803; GO:0043234; GO:0045178; GO:0048471; GO:0051260; GO:0051289; GO:0055074; GO:0097421; GO:1903492; GO:1903861; GO:1904692; GO:1904699; GO:1990785; GO:1990798; GO:1990864; GO:1990867; GO:1990869; GO:1990878	0	0	0	PF00059;	3949	m.44791	157243	29805	74519.5	457445	715383	17757.5	167426.6667	18565	1047033.333	1095611.75	1.635807035
CHOYP_LOC100711559.1.1	Q6NW52	m.10313	sp	MSRB2_DANRE	70.079	127	38	0	64	190	50	176	4.42E-65	201	MSRB2_DANRE	reviewed	"Methionine-R-sulfoxide reductase B2, mitochondrial (MsrB2) (EC 1.8.4.-)"	msrb2 zgc:85965	Danio rerio (Zebrafish) (Brachydanio rerio)	180	actin filament polymerization [GO:0030041]; protein repair [GO:0030091]; response to oxidative stress [GO:0006979]	GO:0003779; GO:0005739; GO:0006979; GO:0030041; GO:0030091; GO:0033743; GO:0046872	0	0	0	PF01641;	3978	m.10313	38624	72782.5	406638	517682	7876774.333	1047783	277814.5	1184173	320791.5	239474.5	0.344464091
CHOYP_LOC100720996.1.1	Q9ULJ8	m.24778	sp	NEB1_HUMAN	50	96	48	0	113	208	978	1073	6.17E-25	105	NEB1_HUMAN	reviewed	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A)	PPP1R9A KIAA1222	Homo sapiens (Human)	1098	actin filament organization [GO:0007015]; aging [GO:0007568]; calcium-mediated signaling [GO:0019722]; cellular response to toxic substance [GO:0097237]; excitatory postsynaptic potential [GO:0060079]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of spontaneous neurotransmitter secretion [GO:1904049]; negative regulation of stress fiber assembly [GO:0051497]; neuron projection development [GO:0031175]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of long term synaptic depression [GO:1900454]; positive regulation of protein kinase activity [GO:0045860]; regulation of actin filament polymerization [GO:0030833]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of filopodium assembly [GO:0051489]; regulation of synapse assembly [GO:0051963]; regulation of synapse structural plasticity [GO:0051823]	GO:0005737; GO:0005829; GO:0007015; GO:0007568; GO:0014069; GO:0015629; GO:0019722; GO:0030054; GO:0030175; GO:0030425; GO:0030833; GO:0030864; GO:0031175; GO:0031594; GO:0043025; GO:0044326; GO:0045860; GO:0051015; GO:0051489; GO:0051497; GO:0051823; GO:0051963; GO:0060079; GO:0060999; GO:0061001; GO:0097237; GO:1900272; GO:1900454; GO:1904049; GO:1990761	0	0	0	PF00595;PF07647;	3984	m.24778	NA	13782	87759	32629	38977	310425	30935	NA	160199	NA	3.862298124
CHOYP_LOC100744089.1.1	Q7ZVK3	m.58530	sp	SIR2_DANRE	53.134	367	145	8	10	368	20	367	1.88E-124	366	SIR2_DANRE	reviewed	NAD-dependent protein deacetylase sirtuin-2 (EC 3.5.1.-) (Regulatory protein SIR2 homolog 2) (SIR2-like protein 2)	sirt2 zgc:77003	Danio rerio (Zebrafish) (Brachydanio rerio)	379	cellular response to caloric restriction [GO:0061433]; cellular response to hypoxia [GO:0071456]; cellular response to oxidative stress [GO:0034599]; cilium morphogenesis [GO:0060271]; histone H4 deacetylation [GO:0070933]; negative regulation of autophagy [GO:0010507]; negative regulation of cell proliferation [GO:0008285]; negative regulation of oligodendrocyte progenitor proliferation [GO:0070446]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061428]; positive regulation of DNA binding [GO:0043388]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia [GO:2000777]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein deacetylation [GO:0006476]; regulation of cell cycle [GO:0051726]; tubulin deacetylation [GO:0090042]	GO:0000122; GO:0004407; GO:0005634; GO:0005694; GO:0005720; GO:0005737; GO:0005813; GO:0005814; GO:0005819; GO:0005829; GO:0006476; GO:0008270; GO:0008285; GO:0010507; GO:0030496; GO:0032436; GO:0033010; GO:0033270; GO:0034599; GO:0034979; GO:0042177; GO:0042903; GO:0043204; GO:0043209; GO:0043220; GO:0043388; GO:0044224; GO:0045944; GO:0046970; GO:0048471; GO:0051726; GO:0060271; GO:0061428; GO:0061433; GO:0070403; GO:0070446; GO:0070933; GO:0071456; GO:0072686; GO:0072687; GO:0090042; GO:0097386; GO:1900119; GO:2000378; GO:2000777	0	0	0	PF02146;	4005	m.58530	326315	40446	97110	197819.5	50139	341792	61122	169866	1138766.5	213182.6667	2.703918799
CHOYP_LOC100867381.1.8	Q9BX66	m.2154	sp	SRBS1_HUMAN	31.232	714	346	30	979	1617	286	929	7.90E-54	211	SRBS1_HUMAN	reviewed	Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3 domain protein 5) (SH3P12) (c-Cbl-associated protein) (CAP)	SORBS1 KIAA0894 KIAA1296 SH3D5	Homo sapiens (Human)	1292	cell-matrix adhesion [GO:0007160]; cellular response to insulin stimulus [GO:0032869]; focal adhesion assembly [GO:0048041]; glucose transport [GO:0015758]; insulin receptor signaling pathway [GO:0008286]; muscle contraction [GO:0006936]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; positive regulation of glucose import [GO:0046326]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of lipid biosynthetic process [GO:0046889]; stress fiber assembly [GO:0043149]	GO:0001725; GO:0003779; GO:0005070; GO:0005158; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0005829; GO:0005886; GO:0005913; GO:0005915; GO:0005924; GO:0005925; GO:0006936; GO:0007160; GO:0008092; GO:0008286; GO:0015758; GO:0016363; GO:0032869; GO:0043149; GO:0045121; GO:0045725; GO:0046326; GO:0046889; GO:0048041; GO:0090004	0	0	0	PF00018;PF07653;PF14604;PF02208;	4051	m.2154	489024.5714	227205.1429	229012.4444	662785.75	113703	193873.9	191588	300778.25	1539476.182	332340.5	1.485747174
CHOYP_LOC100867381.2.8	Q9BX66	m.14977	sp	SRBS1_HUMAN	31.215	724	346	29	466	1117	286	929	4.94E-58	224	SRBS1_HUMAN	reviewed	Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3 domain protein 5) (SH3P12) (c-Cbl-associated protein) (CAP)	SORBS1 KIAA0894 KIAA1296 SH3D5	Homo sapiens (Human)	1292	cell-matrix adhesion [GO:0007160]; cellular response to insulin stimulus [GO:0032869]; focal adhesion assembly [GO:0048041]; glucose transport [GO:0015758]; insulin receptor signaling pathway [GO:0008286]; muscle contraction [GO:0006936]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; positive regulation of glucose import [GO:0046326]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of lipid biosynthetic process [GO:0046889]; stress fiber assembly [GO:0043149]	GO:0001725; GO:0003779; GO:0005070; GO:0005158; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0005829; GO:0005886; GO:0005913; GO:0005915; GO:0005924; GO:0005925; GO:0006936; GO:0007160; GO:0008092; GO:0008286; GO:0015758; GO:0016363; GO:0032869; GO:0043149; GO:0045121; GO:0045725; GO:0046326; GO:0046889; GO:0048041; GO:0090004	0	0	0	PF00018;PF07653;PF14604;PF02208;	4052	m.14977	489024.5714	227205.1429	229012.4444	662785.75	113703	193873.9	191588	300778.25	1539476.182	332340.5	1.485747174
CHOYP_LOC100867381.3.8	Q9BX66	m.15890	sp	SRBS1_HUMAN	31.03	709	334	31	406	1025	287	929	8.07E-55	213	SRBS1_HUMAN	reviewed	Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3 domain protein 5) (SH3P12) (c-Cbl-associated protein) (CAP)	SORBS1 KIAA0894 KIAA1296 SH3D5	Homo sapiens (Human)	1292	cell-matrix adhesion [GO:0007160]; cellular response to insulin stimulus [GO:0032869]; focal adhesion assembly [GO:0048041]; glucose transport [GO:0015758]; insulin receptor signaling pathway [GO:0008286]; muscle contraction [GO:0006936]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; positive regulation of glucose import [GO:0046326]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of lipid biosynthetic process [GO:0046889]; stress fiber assembly [GO:0043149]	GO:0001725; GO:0003779; GO:0005070; GO:0005158; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0005829; GO:0005886; GO:0005913; GO:0005915; GO:0005924; GO:0005925; GO:0006936; GO:0007160; GO:0008092; GO:0008286; GO:0015758; GO:0016363; GO:0032869; GO:0043149; GO:0045121; GO:0045725; GO:0046326; GO:0046889; GO:0048041; GO:0090004	0	0	0	PF00018;PF07653;PF14604;PF02208;	4053	m.15890	489024.5714	227205.1429	229012.4444	662785.75	113703	193873.9	191588	300778.25	1539476.182	332340.5	1.485747174
CHOYP_LOC100867381.4.8	Q9BX66	m.28245	sp	SRBS1_HUMAN	33.034	669	315	27	305	865	286	929	5.05E-64	241	SRBS1_HUMAN	reviewed	Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3 domain protein 5) (SH3P12) (c-Cbl-associated protein) (CAP)	SORBS1 KIAA0894 KIAA1296 SH3D5	Homo sapiens (Human)	1292	cell-matrix adhesion [GO:0007160]; cellular response to insulin stimulus [GO:0032869]; focal adhesion assembly [GO:0048041]; glucose transport [GO:0015758]; insulin receptor signaling pathway [GO:0008286]; muscle contraction [GO:0006936]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; positive regulation of glucose import [GO:0046326]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of lipid biosynthetic process [GO:0046889]; stress fiber assembly [GO:0043149]	GO:0001725; GO:0003779; GO:0005070; GO:0005158; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0005829; GO:0005886; GO:0005913; GO:0005915; GO:0005924; GO:0005925; GO:0006936; GO:0007160; GO:0008092; GO:0008286; GO:0015758; GO:0016363; GO:0032869; GO:0043149; GO:0045121; GO:0045725; GO:0046326; GO:0046889; GO:0048041; GO:0090004	0	0	0	PF00018;PF07653;PF14604;PF02208;	4054	m.28245	489024.5714	227205.1429	229012.4444	662785.75	113703	193873.9	191588	300778.25	1539476.182	332340.5	1.485747174
CHOYP_LOC100867381.5.8	Q62417	m.37859	sp	SRBS1_MOUSE	41.434	251	116	7	1480	1720	980	1209	7.50E-44	179	SRBS1_MOUSE	reviewed	Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3 domain protein 5) (SH3P12) (c-Cbl-associated protein) (CAP)	Sorbs1 Kiaa1296 Sh3d5	Mus musculus (Mouse)	1290	cellular response to insulin stimulus [GO:0032869]; focal adhesion assembly [GO:0048041]; glucose transport [GO:0015758]; insulin receptor signaling pathway [GO:0008286]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; positive regulation of glucose import [GO:0046326]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of lipid biosynthetic process [GO:0046889]; stress fiber assembly [GO:0043149]	GO:0001725; GO:0005070; GO:0005158; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0005829; GO:0005856; GO:0005886; GO:0005913; GO:0005924; GO:0005925; GO:0008134; GO:0008286; GO:0015758; GO:0016020; GO:0016363; GO:0019901; GO:0032869; GO:0043149; GO:0045121; GO:0045725; GO:0046326; GO:0046889; GO:0048041; GO:0090004	0	0	0	PF00018;PF07653;PF14604;PF02208;	4055	m.37859	489024.5714	227205.1429	229012.4444	662785.75	113703	193873.9	191588	300778.25	1539476.182	332340.5	1.485747174
CHOYP_LOC100867381.6.8	Q9BX66	m.44771	sp	SRBS1_HUMAN	31.4	707	320	28	979	1583	286	929	1.03E-57	224	SRBS1_HUMAN	reviewed	Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3 domain protein 5) (SH3P12) (c-Cbl-associated protein) (CAP)	SORBS1 KIAA0894 KIAA1296 SH3D5	Homo sapiens (Human)	1292	cell-matrix adhesion [GO:0007160]; cellular response to insulin stimulus [GO:0032869]; focal adhesion assembly [GO:0048041]; glucose transport [GO:0015758]; insulin receptor signaling pathway [GO:0008286]; muscle contraction [GO:0006936]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; positive regulation of glucose import [GO:0046326]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of lipid biosynthetic process [GO:0046889]; stress fiber assembly [GO:0043149]	GO:0001725; GO:0003779; GO:0005070; GO:0005158; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0005829; GO:0005886; GO:0005913; GO:0005915; GO:0005924; GO:0005925; GO:0006936; GO:0007160; GO:0008092; GO:0008286; GO:0015758; GO:0016363; GO:0032869; GO:0043149; GO:0045121; GO:0045725; GO:0046326; GO:0046889; GO:0048041; GO:0090004	0	0	0	PF00018;PF07653;PF14604;PF02208;	4056	m.44771	489024.5714	227205.1429	229012.4444	662785.75	113703	193873.9	191588	300778.25	1539476.182	332340.5	1.485747174
CHOYP_LOC100867381.7.8	Q9BX66	m.50678	sp	SRBS1_HUMAN	30.844	723	321	28	305	927	286	929	9.60E-57	219	SRBS1_HUMAN	reviewed	Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3 domain protein 5) (SH3P12) (c-Cbl-associated protein) (CAP)	SORBS1 KIAA0894 KIAA1296 SH3D5	Homo sapiens (Human)	1292	cell-matrix adhesion [GO:0007160]; cellular response to insulin stimulus [GO:0032869]; focal adhesion assembly [GO:0048041]; glucose transport [GO:0015758]; insulin receptor signaling pathway [GO:0008286]; muscle contraction [GO:0006936]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; positive regulation of glucose import [GO:0046326]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of lipid biosynthetic process [GO:0046889]; stress fiber assembly [GO:0043149]	GO:0001725; GO:0003779; GO:0005070; GO:0005158; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0005829; GO:0005886; GO:0005913; GO:0005915; GO:0005924; GO:0005925; GO:0006936; GO:0007160; GO:0008092; GO:0008286; GO:0015758; GO:0016363; GO:0032869; GO:0043149; GO:0045121; GO:0045725; GO:0046326; GO:0046889; GO:0048041; GO:0090004	0	0	0	PF00018;PF07653;PF14604;PF02208;	4057	m.50678	489024.5714	227205.1429	229012.4444	662785.75	113703	193873.9	191588	300778.25	1539476.182	332340.5	1.485747174
CHOYP_LOC100867381.8.8	Q62417	m.53059	sp	SRBS1_MOUSE	41.434	251	116	7	1434	1674	980	1209	3.17E-44	180	SRBS1_MOUSE	reviewed	Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3 domain protein 5) (SH3P12) (c-Cbl-associated protein) (CAP)	Sorbs1 Kiaa1296 Sh3d5	Mus musculus (Mouse)	1290	cellular response to insulin stimulus [GO:0032869]; focal adhesion assembly [GO:0048041]; glucose transport [GO:0015758]; insulin receptor signaling pathway [GO:0008286]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; positive regulation of glucose import [GO:0046326]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of lipid biosynthetic process [GO:0046889]; stress fiber assembly [GO:0043149]	GO:0001725; GO:0005070; GO:0005158; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0005829; GO:0005856; GO:0005886; GO:0005913; GO:0005924; GO:0005925; GO:0008134; GO:0008286; GO:0015758; GO:0016020; GO:0016363; GO:0019901; GO:0032869; GO:0043149; GO:0045121; GO:0045725; GO:0046326; GO:0046889; GO:0048041; GO:0090004	0	0	0	PF00018;PF07653;PF14604;PF02208;	4058	m.53059	489024.5714	227205.1429	229012.4444	662785.75	113703	193873.9	191588	300778.25	1539476.182	332340.5	1.485747174
CHOYP_LOC100875671.1.1	Q62417	m.57087	sp	SRBS1_MOUSE	42.231	251	114	8	491	731	980	1209	1.09E-44	179	SRBS1_MOUSE	reviewed	Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3 domain protein 5) (SH3P12) (c-Cbl-associated protein) (CAP)	Sorbs1 Kiaa1296 Sh3d5	Mus musculus (Mouse)	1290	cellular response to insulin stimulus [GO:0032869]; focal adhesion assembly [GO:0048041]; glucose transport [GO:0015758]; insulin receptor signaling pathway [GO:0008286]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; positive regulation of glucose import [GO:0046326]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of lipid biosynthetic process [GO:0046889]; stress fiber assembly [GO:0043149]	GO:0001725; GO:0005070; GO:0005158; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0005829; GO:0005856; GO:0005886; GO:0005913; GO:0005924; GO:0005925; GO:0008134; GO:0008286; GO:0015758; GO:0016020; GO:0016363; GO:0019901; GO:0032869; GO:0043149; GO:0045121; GO:0045725; GO:0046326; GO:0046889; GO:0048041; GO:0090004	0	0	0	PF00018;PF07653;PF14604;PF02208;	4069	m.57087	563369	259214.8333	195476.6667	732535.7143	125162.6667	199416.8571	213987.5	340114.1429	1662404.7	346887.4	1.472902849
CHOYP_LOC100880757.1.2	P41777	m.19188	sp	NOLC1_RAT	56.818	88	37	1	362	448	617	704	9.23E-24	107	NOLC1_RAT	reviewed	Nucleolar and coiled-body phosphoprotein 1 (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar 130 kDa protein) (Nucleolar phosphoprotein p130)	Nolc1	Rattus norvegicus (Rat)	704	"box H/ACA snoRNA metabolic process [GO:0033979]; positive regulation of cell proliferation [GO:0008284]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of protein import into nucleus [GO:0042306]; response to osmotic stress [GO:0006970]"	GO:0003700; GO:0005524; GO:0005525; GO:0005654; GO:0005730; GO:0005737; GO:0006970; GO:0008134; GO:0008139; GO:0008284; GO:0019904; GO:0033979; GO:0034512; GO:0034513; GO:0042306; GO:0045893	0	0	0	PF05022;	4102	m.19188	234012.6667	19351.5	370541	99151	247817.6667	776612.5	41635	18735	576809	494931.6	1.965984698
CHOYP_LOC100893535.1.1	O43396	m.27958	sp	TXNL1_HUMAN	55.052	287	125	3	27	310	4	289	3.10E-113	332	TXNL1_HUMAN	reviewed	Thioredoxin-like protein 1 (32 kDa thioredoxin-related protein)	TXNL1 TRP32 TXL TXNL	Homo sapiens (Human)	289	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glycerol ether metabolic process [GO:0006662]; protein folding [GO:0006457]; sulfate assimilation [GO:0000103]	GO:0000103; GO:0000502; GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0006662; GO:0015035; GO:0015036; GO:0016671; GO:0034599; GO:0045454; GO:0070062	0	0	0	PF06201;PF00085;	4148	m.27958	504370.7143	84335	185717.4	6961696.571	399403.25	1272540.143	161912	197437.8	2654498.9	527442.625	0.59170523
CHOYP_LOC100929680.1.2	P15941	m.17333	sp	MUC1_HUMAN	37.158	915	459	32	2995	3843	78	942	6.20E-48	194	MUC1_HUMAN	reviewed	Mucin-1 (MUC-1) (Breast carcinoma-associated antigen DF3) (Cancer antigen 15-3) (CA 15-3) (Carcinoma-associated mucin) (Episialin) (H23AG) (Krebs von den Lungen-6) (KL-6) (PEMT) (Peanut-reactive urinary mucin) (PUM) (Polymorphic epithelial mucin) (PEM) (Tumor-associated epithelial membrane antigen) (EMA) (Tumor-associated mucin) (CD antigen CD227) [Cleaved into: Mucin-1 subunit alpha (MUC1-NT) (MUC1-alpha); Mucin-1 subunit beta (MUC1-beta) (MUC1-CT)]	MUC1 PUM	Homo sapiens (Human)	1255	"DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of transcription by competitive promoter binding [GO:0010944]; O-glycan processing [GO:0016266]; positive regulation of histone H4 acetylation [GO:0090240]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; regulation of transcription from RNA polymerase II promoter in response to stress [GO:0043618]"	GO:0000790; GO:0000978; GO:0002039; GO:0003712; GO:0005615; GO:0005796; GO:0005887; GO:0006977; GO:0006978; GO:0010944; GO:0016266; GO:0016324; GO:0031982; GO:0033629; GO:0036003; GO:0043618; GO:0070062; GO:0090240; GO:1902166	0	0	0	PF01390;	4199	m.17333	431289.3	505597.2857	538416.7273	1202877.5	569909.1818	882394	1194104.5	1179925.333	905584	393979.3636	1.402666553
CHOYP_LOC100929680.2.2	P15941	m.28318	sp	MUC1_HUMAN	37.146	918	461	32	1247	2098	75	942	1.05E-48	196	MUC1_HUMAN	reviewed	Mucin-1 (MUC-1) (Breast carcinoma-associated antigen DF3) (Cancer antigen 15-3) (CA 15-3) (Carcinoma-associated mucin) (Episialin) (H23AG) (Krebs von den Lungen-6) (KL-6) (PEMT) (Peanut-reactive urinary mucin) (PUM) (Polymorphic epithelial mucin) (PEM) (Tumor-associated epithelial membrane antigen) (EMA) (Tumor-associated mucin) (CD antigen CD227) [Cleaved into: Mucin-1 subunit alpha (MUC1-NT) (MUC1-alpha); Mucin-1 subunit beta (MUC1-beta) (MUC1-CT)]	MUC1 PUM	Homo sapiens (Human)	1255	"DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of transcription by competitive promoter binding [GO:0010944]; O-glycan processing [GO:0016266]; positive regulation of histone H4 acetylation [GO:0090240]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; regulation of transcription from RNA polymerase II promoter in response to stress [GO:0043618]"	GO:0000790; GO:0000978; GO:0002039; GO:0003712; GO:0005615; GO:0005796; GO:0005887; GO:0006977; GO:0006978; GO:0010944; GO:0016266; GO:0016324; GO:0031982; GO:0033629; GO:0036003; GO:0043618; GO:0070062; GO:0090240; GO:1902166	0	0	0	PF01390;	4200	m.28318	279292.375	31442	433928	453578.6667	23013	1865226.5	23156	1800895.8	215017.5	40717.5	3.230297027
CHOYP_LOC101070737.1.3	Q9CQZ5	m.1746	sp	NDUA6_MOUSE	53.608	97	45	0	21	117	21	117	2.65E-31	110	NDUA6_MOUSE	reviewed	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (Complex I-B14) (CI-B14) (NADH-ubiquinone oxidoreductase B14 subunit)	Ndufa6	Mus musculus (Mouse)	131	oxidation-reduction process [GO:0055114]; response to oxidative stress [GO:0006979]	GO:0005739; GO:0005747; GO:0006979; GO:0031966; GO:0055114	0	0	0	PF05347;	4243	m.1746	268325	579955.5	660821.5	150287	254186	243418	429551	110335	NA	248476	0.673987171
CHOYP_LOC101070737.2.3	Q9CQZ5	m.11531	sp	NDUA6_MOUSE	56.757	111	48	0	33	143	21	131	5.80E-42	138	NDUA6_MOUSE	reviewed	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (Complex I-B14) (CI-B14) (NADH-ubiquinone oxidoreductase B14 subunit)	Ndufa6	Mus musculus (Mouse)	131	oxidation-reduction process [GO:0055114]; response to oxidative stress [GO:0006979]	GO:0005739; GO:0005747; GO:0006979; GO:0031966; GO:0055114	0	0	0	PF05347;	4244	m.11531	268325	579955.5	660821.5	150287	254186	243418	429551	110335	NA	248476	0.673987171
CHOYP_LOC101070737.3.3	Q9CQZ5	m.20342	sp	NDUA6_MOUSE	56.25	112	49	0	19	130	20	131	6.48E-42	138	NDUA6_MOUSE	reviewed	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (Complex I-B14) (CI-B14) (NADH-ubiquinone oxidoreductase B14 subunit)	Ndufa6	Mus musculus (Mouse)	131	oxidation-reduction process [GO:0055114]; response to oxidative stress [GO:0006979]	GO:0005739; GO:0005747; GO:0006979; GO:0031966; GO:0055114	0	0	0	PF05347;	4245	m.20342	268325	579955.5	660821.5	150287	254186	243418	429551	110335	NA	248476	0.673987171
CHOYP_LOC101169658.1.3	Q08420	m.18820	sp	SODE_RAT	29.268	164	96	7	318	467	65	222	1.04E-08	59.3	SODE_RAT	reviewed	Extracellular superoxide dismutase [Cu-Zn] (EC-SOD) (EC 1.15.1.1) (Superoxide dismutase B)	Sod3 Sod-3	Rattus norvegicus (Rat)	244	response to copper ion [GO:0046688]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]; response to superoxide [GO:0000303]	GO:0000303; GO:0001666; GO:0004784; GO:0005507; GO:0005615; GO:0005634; GO:0005737; GO:0005802; GO:0006979; GO:0008270; GO:0031012; GO:0046688; GO:0070062	0	0	cd00305;	PF00080;	4295	m.18820	3199548.667	31548	NA	34315	558122	644544.5	NA	219611	102210	345421	0.343082241
CHOYP_LOC101169658.2.3	Q08420	m.20752	sp	SODE_RAT	25.654	191	112	8	147	323	48	222	4.94E-09	59.3	SODE_RAT	reviewed	Extracellular superoxide dismutase [Cu-Zn] (EC-SOD) (EC 1.15.1.1) (Superoxide dismutase B)	Sod3 Sod-3	Rattus norvegicus (Rat)	244	response to copper ion [GO:0046688]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]; response to superoxide [GO:0000303]	GO:0000303; GO:0001666; GO:0004784; GO:0005507; GO:0005615; GO:0005634; GO:0005737; GO:0005802; GO:0006979; GO:0008270; GO:0031012; GO:0046688; GO:0070062	0	0	cd00305;	PF00080;	4296	m.20752	149280	127898	715463.6	218126.3333	144283	501606.1429	376881.6667	846515.83	427851.1667	385176.1667	1.873015184
CHOYP_LOC579737.1.1	Q64350	m.14356	sp	EI2BE_RAT	40.087	686	376	12	30	687	38	716	7.49E-164	491	EI2BE_RAT	reviewed	Translation initiation factor eIF-2B subunit epsilon (eIF-2B GDP-GTP exchange factor subunit epsilon)	Eif2b5 Eif2be	Rattus norvegicus (Rat)	716	aging [GO:0007568]; astrocyte development [GO:0014002]; astrocyte differentiation [GO:0048708]; cellular response to drug [GO:0035690]; hippocampus development [GO:0021766]; myelination [GO:0042552]; oligodendrocyte development [GO:0014003]; ovarian follicle development [GO:0001541]; positive regulation of apoptotic process [GO:0043065]; positive regulation of translation [GO:0045727]; positive regulation of translational initiation [GO:0045948]; response to endoplasmic reticulum stress [GO:0034976]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to lithium ion [GO:0010226]; response to peptide hormone [GO:0043434]; translational initiation [GO:0006413]	GO:0001541; GO:0003743; GO:0005085; GO:0005634; GO:0005737; GO:0005851; GO:0006413; GO:0007568; GO:0009408; GO:0009749; GO:0010226; GO:0014002; GO:0014003; GO:0021766; GO:0031369; GO:0034976; GO:0035690; GO:0042552; GO:0043065; GO:0043434; GO:0045727; GO:0045948; GO:0048708	0	0	0	PF00132;PF02020;	4435	m.14356	2481403	917910.5	448945.75	408889	34092	755422.6	839856.4	2704728	1576041.333	2507937.75	1.953744278
CHOYP_LOC580840.1.1	Q55G87	m.45393	sp	CANB1_DICDI	24.419	172	128	1	1	172	1	170	1.50E-15	73.6	CANB1_DICDI	reviewed	Calcineurin subunit B type 1 (Calcineurin regulatory subunit 1) (Protein phosphatase 2B regulatory subunit 1)	cnbA DDB_G0267446	Dictyostelium discoideum (Slime mold)	180	positive regulation of sorocarp stalk cell differentiation [GO:0031287]; protein dephosphorylation [GO:0006470]; response to cation stress [GO:0043157]	GO:0005509; GO:0005955; GO:0006470; GO:0031287; GO:0043157	0	0	0	PF13499;	4447	m.45392	16517063.6	94408	11698471	58436894.5	1016621	122196.5	295433	2671174.333	17990891.67	190514.6667	0.242358387
CHOYP_LOC586494.1.1	Q96T60	m.50214	sp	PNKP_HUMAN	43.75	352	195	3	85	434	153	503	5.64E-95	299	PNKP_HUMAN	reviewed	Bifunctional polynucleotide phosphatase/kinase (DNA 5'-kinase/3'-phosphatase) (Polynucleotide kinase-3'-phosphatase) [Includes: Polynucleotide 3'-phosphatase (EC 3.1.3.32) (2'(3')-polynucleotidase); Polynucleotide 5'-hydroxyl-kinase (EC 2.7.1.78)]	PNKP	Homo sapiens (Human)	521	"dephosphorylation [GO:0016311]; DNA 3' dephosphorylation involved in DNA repair [GO:0098504]; DNA damage response, detection of DNA damage [GO:0042769]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; nucleotide-excision repair, DNA damage removal [GO:0000718]; nucleotide phosphorylation [GO:0046939]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]"	GO:0000718; GO:0003684; GO:0003690; GO:0004519; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0006261; GO:0006281; GO:0006979; GO:0009314; GO:0016020; GO:0016311; GO:0017076; GO:0019201; GO:0032212; GO:0042769; GO:0046403; GO:0046404; GO:0046939; GO:0051973; GO:0098504; GO:1904355	0	0	0	PF08645;	4508	m.50214	38352	196480	17034	197169	231756.5	19112	182532	317064.5	4283751.667	309445	7.508767614
CHOYP_LOC587133.1.1	P72745	m.61281	sp	Y1101_SYNY3	38.835	103	61	1	51	151	6	108	8.99E-15	68.9	Y1101_SYNY3	reviewed	Universal stress protein Slr1101 (USP Slr1101)	slr1101	Synechocystis sp. (strain PCC 6803 / Kazusa)	108	response to stress [GO:0006950]	GO:0006950	0	0	0	PF00582;	4514	m.61281	NA	61208.5	149232.5	5246573.6	380694.2	340942.6667	30429	483893.75	64313.5	1747485.333	0.365494661
CHOYP_LOC589012.1.1	P16056	m.26892	sp	MET_MOUSE	27.807	748	441	24	42	731	635	1341	4.59E-74	266	MET_MOUSE	reviewed	Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)	Met	Mus musculus (Mouse)	1379	activation of MAPK activity [GO:0000187]; adult behavior [GO:0030534]; brain development [GO:0007420]; branching morphogenesis of an epithelial tube [GO:0048754]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; chemical synaptic transmission [GO:0007268]; endothelial cell morphogenesis [GO:0001886]; excitatory postsynaptic potential [GO:0060079]; glucose homeostasis [GO:0042593]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; liver development [GO:0001889]; modulation of synaptic transmission [GO:0050804]; muscle cell migration [GO:0014812]; muscle organ development [GO:0007517]; myoblast proliferation [GO:0051450]; myotube differentiation [GO:0014902]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-mediated programmed cell death [GO:1901299]; negative regulation of transforming growth factor beta production [GO:0071635]; placenta development [GO:0001890]; positive chemotaxis [GO:0050918]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of glucose transport [GO:0010828]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein autophosphorylation [GO:0046777]; reactive oxygen species metabolic process [GO:0072593]; regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling [GO:0060665]; regulation of cellular response to oxidative stress [GO:1900407]; regulation of interleukin-6 production [GO:0032675]; semaphorin-plexin signaling pathway [GO:0071526]; skeletal muscle tissue development [GO:0007519]	GO:0000187; GO:0001886; GO:0001889; GO:0001890; GO:0004672; GO:0005008; GO:0005524; GO:0007268; GO:0007420; GO:0007517; GO:0007519; GO:0009925; GO:0009986; GO:0010629; GO:0010828; GO:0014812; GO:0014902; GO:0016020; GO:0016021; GO:0019903; GO:0030534; GO:0032675; GO:0042593; GO:0045944; GO:0046777; GO:0048012; GO:0048754; GO:0050804; GO:0050918; GO:0051450; GO:0055013; GO:0060048; GO:0060079; GO:0060665; GO:0071526; GO:0071635; GO:0072593; GO:0098794; GO:1900407; GO:1900745; GO:1901299; GO:2001028	0	0	0	PF07714;PF01437;PF01403;PF01833;	4533	m.26892	59396	278817.25	441964.5	100422.4	75555	87041.5	1927668	49157	98312.25	69018.25	2.333509368
CHOYP_LOC593522.1.2	Q8VIJ6	m.5381	sp	SFPQ_MOUSE	53.986	276	127	0	137	412	283	558	1.82E-98	317	SFPQ_MOUSE	reviewed	"Splicing factor, proline- and glutamine-rich (DNA-binding p52/p100 complex, 100 kDa subunit) (Polypyrimidine tract-binding protein-associated-splicing factor) (PSF) (PTB-associated-splicing factor)"	Sfpq Psf	Mus musculus (Mouse)	699	"alternative mRNA splicing, via spliceosome [GO:0000380]; cellular response to DNA damage stimulus [GO:0006974]; chromosome organization [GO:0051276]; double-strand break repair via homologous recombination [GO:0000724]; histone H3 deacetylation [GO:0070932]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of sister chromatid cohesion [GO:0045876]; regulation of cell cycle [GO:0051726]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]"	GO:0000122; GO:0000166; GO:0000380; GO:0000724; GO:0000785; GO:0000976; GO:0000980; GO:0001047; GO:0003682; GO:0005634; GO:0005654; GO:0005737; GO:0006351; GO:0006974; GO:0016363; GO:0042382; GO:0042752; GO:0042754; GO:0042826; GO:0044212; GO:0044822; GO:0045876; GO:0045892; GO:0048511; GO:0051276; GO:0051726; GO:0070932; GO:0090575; GO:1902177	0	0	0	PF08075;PF00076;	4576	m.5381	702141.75	5968319.625	3565680.667	693003.8571	240771.2222	572577.5	13249886.14	2090472.3	32003783.67	1434927.167	4.418264365
CHOYP_LOC593522.2.2	Q8VIJ6	m.33859	sp	SFPQ_MOUSE	53.986	276	127	0	61	336	283	558	2.27E-99	313	SFPQ_MOUSE	reviewed	"Splicing factor, proline- and glutamine-rich (DNA-binding p52/p100 complex, 100 kDa subunit) (Polypyrimidine tract-binding protein-associated-splicing factor) (PSF) (PTB-associated-splicing factor)"	Sfpq Psf	Mus musculus (Mouse)	699	"alternative mRNA splicing, via spliceosome [GO:0000380]; cellular response to DNA damage stimulus [GO:0006974]; chromosome organization [GO:0051276]; double-strand break repair via homologous recombination [GO:0000724]; histone H3 deacetylation [GO:0070932]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of sister chromatid cohesion [GO:0045876]; regulation of cell cycle [GO:0051726]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]"	GO:0000122; GO:0000166; GO:0000380; GO:0000724; GO:0000785; GO:0000976; GO:0000980; GO:0001047; GO:0003682; GO:0005634; GO:0005654; GO:0005737; GO:0006351; GO:0006974; GO:0016363; GO:0042382; GO:0042752; GO:0042754; GO:0042826; GO:0044212; GO:0044822; GO:0045876; GO:0045892; GO:0048511; GO:0051276; GO:0051726; GO:0070932; GO:0090575; GO:1902177	0	0	0	PF08075;PF00076;	4577	m.33859	702141.75	5968319.625	3565680.667	693003.8571	240771.2222	572577.5	13249886.14	2090472.3	32003783.67	1434927.167	4.418264365
CHOYP_LOC656201.1.1	Q13148	m.8657	sp	TADBP_HUMAN	49.423	433	170	12	1	429	1	388	6.76E-123	367	TADBP_HUMAN	reviewed	TAR DNA-binding protein 43 (TDP-43)	TARDBP TDP43	Homo sapiens (Human)	414	3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA processing [GO:0006397]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of gene expression [GO:0010629]; negative regulation of protein phosphorylation [GO:0001933]; nuclear fragmentation involved in apoptotic nuclear change [GO:0030264]; nuclear inner membrane organization [GO:0071765]; positive regulation of insulin secretion [GO:0032024]; regulation of cell cycle [GO:0051726]; response to endoplasmic reticulum stress [GO:0034976]; RNA splicing [GO:0008380]; transcription from RNA polymerase II promoter [GO:0006366]	GO:0000166; GO:0001205; GO:0001933; GO:0003690; GO:0003700; GO:0003723; GO:0003730; GO:0005634; GO:0005654; GO:0005726; GO:0005737; GO:0006366; GO:0006397; GO:0008380; GO:0010629; GO:0016607; GO:0030264; GO:0032024; GO:0034976; GO:0035061; GO:0042802; GO:0043922; GO:0044822; GO:0051726; GO:0070935; GO:0071765	0	0	0	PF00076;	4595	m.8657	1037240.833	274641.75	417983.25	46186	733437.4	117715.5	1412566.75	53143.66667	275626.75	3391486.833	2.092274169
CHOYP_LOC658201.1.1	O43639	m.42879	sp	NCK2_HUMAN	41.606	411	199	13	4	407	3	379	4.49E-96	295	NCK2_HUMAN	reviewed	Cytoplasmic protein NCK2 (Growth factor receptor-bound protein 4) (NCK adaptor protein 2) (Nck-2) (SH2/SH3 adaptor protein NCK-beta)	NCK2 GRB4	Homo sapiens (Human)	380	actin filament organization [GO:0007015]; cell migration [GO:0016477]; dendritic spine development [GO:0060996]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; immunological synapse formation [GO:0001771]; lamellipodium assembly [GO:0030032]; negative regulation of cell proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation [GO:1903912]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990441]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902237]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of translation in response to endoplasmic reticulum stress [GO:0036493]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vesicle-mediated transport [GO:0016192]	GO:0001771; GO:0005070; GO:0005086; GO:0005737; GO:0005783; GO:0005802; GO:0005829; GO:0007015; GO:0007165; GO:0007172; GO:0007173; GO:0007176; GO:0008093; GO:0008285; GO:0012506; GO:0016192; GO:0016477; GO:0030032; GO:0030159; GO:0030838; GO:0033137; GO:0036493; GO:0042102; GO:0042110; GO:0045202; GO:0045944; GO:0048010; GO:0048013; GO:0060996; GO:1902237; GO:1903898; GO:1903912; GO:1990441	0	0	0	PF00017;PF00018;PF14604;	4613	m.42880	18107520.81	1802925.625	11459912.86	28080285.21	19248978.69	18088344.08	18332420.71	15043990.74	961453.2	16154025.25	0.871417565
CHOYP_LOC658201.1.1	O43639	m.42879	sp	NCK2_HUMAN	41.606	411	199	13	4	407	3	379	4.49E-96	295	NCK2_HUMAN	reviewed	Cytoplasmic protein NCK2 (Growth factor receptor-bound protein 4) (NCK adaptor protein 2) (Nck-2) (SH2/SH3 adaptor protein NCK-beta)	NCK2 GRB4	Homo sapiens (Human)	380	actin filament organization [GO:0007015]; cell migration [GO:0016477]; dendritic spine development [GO:0060996]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; immunological synapse formation [GO:0001771]; lamellipodium assembly [GO:0030032]; negative regulation of cell proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation [GO:1903912]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990441]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902237]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of translation in response to endoplasmic reticulum stress [GO:0036493]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vesicle-mediated transport [GO:0016192]	GO:0001771; GO:0005070; GO:0005086; GO:0005737; GO:0005783; GO:0005802; GO:0005829; GO:0007015; GO:0007165; GO:0007172; GO:0007173; GO:0007176; GO:0008093; GO:0008285; GO:0012506; GO:0016192; GO:0016477; GO:0030032; GO:0030159; GO:0030838; GO:0033137; GO:0036493; GO:0042102; GO:0042110; GO:0045202; GO:0045944; GO:0048010; GO:0048013; GO:0060996; GO:1902237; GO:1903898; GO:1903912; GO:1990441	0	0	0	PF00017;PF00018;PF14604;	4614	m.42881	5532335.333	367878.2	526952.6	118395	239045.3333	855149.3333	46376.5	49216.75	1146716.667	2856372.333	0.730157542
CHOYP_LOC660338.1.1	Q91W90	m.33595	sp	TXND5_MOUSE	46.486	370	186	4	29	390	52	417	5.86E-121	359	TXND5_MOUSE	reviewed	Thioredoxin domain-containing protein 5 (Endoplasmic reticulum resident protein 46) (ER protein 46) (ERp46) (Plasma cell-specific thioredoxin-related protein) (PC-TRP) (Thioredoxin-like protein p46)	Txndc5 Tlp46	Mus musculus (Mouse)	417	apoptotic cell clearance [GO:0043277]; cell redox homeostasis [GO:0045454]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976]	GO:0003756; GO:0005788; GO:0006457; GO:0034976; GO:0043277; GO:0045454; GO:0070062	0	0	0	PF00085;	4644	m.33595	127774	104850	102122	83192	57765.66667	93535.6	92111	37998.75	101802.6	334672.75	1.387672087
CHOYP_LOC662357.1.1	P72745	m.64856	sp	Y1101_SYNY3	49.02	51	26	0	59	109	53	103	1.87E-10	56.6	Y1101_SYNY3	reviewed	Universal stress protein Slr1101 (USP Slr1101)	slr1101	Synechocystis sp. (strain PCC 6803 / Kazusa)	108	response to stress [GO:0006950]	GO:0006950	0	0	0	PF00582;	4667	m.64856	1420350	632221.4444	812775.0909	2180244.077	317680.2727	341688.0909	359091.8	1149345.286	6581515.083	693967.0769	1.701500359
CHOYP_LOC732900.1.1	Q641Y2	m.62814	sp	NDUS2_RAT	74.596	433	106	2	50	480	33	463	0	694	NDUS2_RAT	reviewed	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3) (Complex I-49kD) (CI-49kD) (NADH-ubiquinone oxidoreductase 49 kDa subunit)"	Ndufs2	Rattus norvegicus (Rat)	463	response to oxidative stress [GO:0006979]	GO:0005654; GO:0005747; GO:0006979; GO:0008137; GO:0046872; GO:0048038; GO:0051287; GO:0051539	0	0	0	PF00346;	4690	m.62814	611978.2857	71807	151885.8571	607586.3636	364593.375	211992.1111	327024.4286	268393.7	928690.7778	680148.3571	1.336531348
CHOYP_LOC754102.1.1	O07552	m.57575	sp	NHAX_BACSU	25.466	161	102	4	8	151	7	166	2.50E-10	59.3	NHAX_BACSU	reviewed	Stress response protein NhaX	nhaX yheK BSU09690	Bacillus subtilis (strain 168)	166	response to stress [GO:0006950]	GO:0006950	0	0	0	PF00582;	4702	m.57574	74768114	26086527	29808588.13	15096453.5	38162449.78	47981938.4	57023774.63	36178584.88	133947494.7	39203266.57	1.709065978
CHOYP_LOC754102.1.1	O07552	m.57575	sp	NHAX_BACSU	25.466	161	102	4	8	151	7	166	2.50E-10	59.3	NHAX_BACSU	reviewed	Stress response protein NhaX	nhaX yheK BSU09690	Bacillus subtilis (strain 168)	166	response to stress [GO:0006950]	GO:0006950	0	0	0	PF00582;	4703	m.57575	532078	261872	31404	1719258	34738	365047	44684	178120.5	1010793	80591.5	0.651030686
CHOYP_LOC754102.1.1	O07552	m.57575	sp	NHAX_BACSU	25.466	161	102	4	8	151	7	166	2.50E-10	59.3	NHAX_BACSU	reviewed	Stress response protein NhaX	nhaX yheK BSU09690	Bacillus subtilis (strain 168)	166	response to stress [GO:0006950]	GO:0006950	0	0	0	PF00582;	4704	m.57578	92633.5	232393.5714	1086489	174239.5	216741.3333	91322.2	1256973	515564.8333	1262933.222	111293.7143	1.796445232
CHOYP_LONM.1.1	Q8CGK3	m.7031	sp	LONM_MOUSE	56.443	939	362	11	80	1010	41	940	0	1064	LONM_MOUSE	reviewed	"Lon protease homolog, mitochondrial (EC 3.4.21.-) (Lon protease-like protein) (LONP) (Mitochondrial ATP-dependent protease Lon) (Serine protease 15)"	Lonp1 Prss15	Mus musculus (Mouse)	949	aging [GO:0007568]; cellular response to oxidative stress [GO:0034599]; chaperone-mediated protein complex assembly [GO:0051131]; misfolded or incompletely synthesized protein catabolic process [GO:0006515]; mitochondrion organization [GO:0007005]; oxidation-dependent protein catabolic process [GO:0070407]; protein homooligomerization [GO:0051260]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of mitochondrial DNA replication [GO:0090296]; response to aluminum ion [GO:0010044]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]	GO:0001666; GO:0003697; GO:0003727; GO:0004176; GO:0004252; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005759; GO:0006508; GO:0006515; GO:0007005; GO:0007568; GO:0009725; GO:0010044; GO:0016020; GO:0016887; GO:0034599; GO:0042645; GO:0043531; GO:0043565; GO:0051131; GO:0051260; GO:0051603; GO:0051880; GO:0070182; GO:0070361; GO:0070407; GO:0090296	0	0	0	PF00004;PF05362;PF02190;	4738	m.7031	341798.3636	228530.4545	1670853.929	462345.0769	8692922.643	279741.8333	6474960.125	382523.8182	175739.3529	332510.4737	0.670864637
CHOYP_LR16A.1.3	Q6EDY6	m.9037	sp	CARL1_MOUSE	35.915	1033	517	25	1	986	249	1183	4.14E-178	569	CARL1_MOUSE	reviewed	"F-actin-uncapping protein LRRC16A (CARMIL homolog) (Capping protein, Arp2/3 and myosin-I linker homolog 1) (Capping protein, Arp2/3 and myosin-I linker protein 1) (CARML1) (Leucine-rich repeat-containing protein 16A)"	Lrrc16a Carmil Lrrc16	Mus musculus (Mouse)	1374	actin filament network formation [GO:0051639]; barbed-end actin filament uncapping [GO:0051638]; cell migration [GO:0016477]; establishment or maintenance of cell polarity [GO:0007163]; lamellipodium assembly [GO:0030032]; macropinocytosis [GO:0044351]; negative regulation of barbed-end actin filament capping [GO:2000813]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell migration [GO:0030335]; positive regulation of lamellipodium organization [GO:1902745]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; ruffle organization [GO:0031529]; urate metabolic process [GO:0046415]	GO:0005634; GO:0005737; GO:0005886; GO:0007163; GO:0016477; GO:0030027; GO:0030032; GO:0030335; GO:0030838; GO:0031252; GO:0031529; GO:0031941; GO:0032403; GO:0044351; GO:0044354; GO:0045111; GO:0046415; GO:0051496; GO:0051638; GO:0051639; GO:0070062; GO:1900026; GO:1902745; GO:2000813	0	0	0	PF16000;PF13516;	4739	m.9037	41137	50095	167309	102155	37349.5	38748	22378	18707	48769	98761	0.571198519
CHOYP_LR16A.3.3	Q5VZK9	m.59538	sp	CARL1_HUMAN	37.909	1253	661	24	4	1214	5	1182	0	788	CARL1_HUMAN	reviewed	"F-actin-uncapping protein LRRC16A (CARMIL homolog) (Capping protein, Arp2/3 and myosin-I linker homolog 1) (Capping protein, Arp2/3 and myosin-I linker protein 1) (Leucine-rich repeat-containing protein 16A)"	LRRC16A CARMIL CARMIL1 LRRC16	Homo sapiens (Human)	1371	actin filament network formation [GO:0051639]; actin filament organization [GO:0007015]; barbed-end actin filament uncapping [GO:0051638]; blood coagulation [GO:0007596]; cell migration [GO:0016477]; lamellipodium assembly [GO:0030032]; macropinocytosis [GO:0044351]; negative regulation of barbed-end actin filament capping [GO:2000813]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell migration [GO:0030335]; positive regulation of lamellipodium organization [GO:1902745]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; ruffle organization [GO:0031529]; urate metabolic process [GO:0046415]	GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0007015; GO:0007596; GO:0016477; GO:0030027; GO:0030032; GO:0030335; GO:0030838; GO:0031252; GO:0031529; GO:0031941; GO:0032403; GO:0044351; GO:0044354; GO:0046415; GO:0051496; GO:0051638; GO:0051639; GO:0070062; GO:1900026; GO:1902745; GO:2000813	0	0	0	PF16000;PF13516;	4740	m.59538	41137	50095	167309	102155	37349.5	38748	22378	18707	48769	98761	0.571198519
CHOYP_MP2K5.1.1	Q13163	m.45311	sp	MP2K5_HUMAN	48.472	458	199	6	1	450	12	440	2.48E-144	422	MP2K5_HUMAN	reviewed	Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase 5) (MAPKK 5) (EC 2.7.12.2) (MAPK/ERK kinase 5) (MEK 5)	MAP2K5 MEK5 MKK5 PRKMK5	Homo sapiens (Human)	448	activation of MAPK activity [GO:0000187]; cellular response to growth factor stimulus [GO:0071363]; cellular response to laminar fluid shear stress [GO:0071499]; ERK5 cascade [GO:0070375]; heart development [GO:0007507]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000342]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of interleukin-8 biosynthetic process [GO:0045415]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of response to cytokine stimulus [GO:0060761]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of cell growth [GO:0030307]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; signal transduction [GO:0007165]	GO:0000122; GO:0000187; GO:0004672; GO:0004702; GO:0004713; GO:0005524; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0007165; GO:0007507; GO:0030307; GO:0032088; GO:0034115; GO:0043154; GO:0045415; GO:0045944; GO:0046872; GO:0050679; GO:0051247; GO:0060761; GO:0070375; GO:0071363; GO:0071499; GO:0090051; GO:2000342; GO:2001240	0	0	0	PF00564;PF00069;	4860	m.45312	2400227.4	2377276.833	2485643.571	545987	1049845.6	1624945.364	1345231.3	782379.4444	17797667.14	6228627	3.13567126
CHOYP_MRP1.10.10	Q8CG09	m.64931	sp	MRP1_RAT	46.497	1570	782	19	4	1554	2	1532	0	1395	MRP1_RAT	reviewed	Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter)	Abcc1 Mrp1	Rattus norvegicus (Rat)	1532	cell chemotaxis [GO:0060326]; daunorubicin transport [GO:0043215]; drug export [GO:0046618]; drug transmembrane transport [GO:0006855]; glutathione transmembrane transport [GO:0034775]; negative regulation of neuron death [GO:1901215]; phospholipid efflux [GO:0033700]; plasma membrane long-chain fatty acid transport [GO:0015911]; positive regulation of cell migration [GO:0030335]; response to drug [GO:0042493]; response to oxidative stress [GO:0006979]; transmembrane transport [GO:0055085]; xenobiotic transport [GO:0042908]	GO:0005324; GO:0005524; GO:0005737; GO:0005886; GO:0005887; GO:0006855; GO:0006979; GO:0008559; GO:0015238; GO:0015431; GO:0015562; GO:0015911; GO:0016020; GO:0016323; GO:0016491; GO:0030335; GO:0033700; GO:0034040; GO:0034634; GO:0034775; GO:0042493; GO:0042908; GO:0043215; GO:0046618; GO:0046624; GO:0055085; GO:0060326; GO:1901215	0	0	0	PF00664;PF00005;	4871	m.64931	70780.33333	34651.66667	293493.5	50868.66667	44886.33333	142494	333917.6667	33090	172906.5	57362.4	1.495451239
CHOYP_MRP1.5.10	Q8CG09	m.34368	sp	MRP1_RAT	48.925	1582	738	20	4	1566	2	1532	0	1486	MRP1_RAT	reviewed	Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter)	Abcc1 Mrp1	Rattus norvegicus (Rat)	1532	cell chemotaxis [GO:0060326]; daunorubicin transport [GO:0043215]; drug export [GO:0046618]; drug transmembrane transport [GO:0006855]; glutathione transmembrane transport [GO:0034775]; negative regulation of neuron death [GO:1901215]; phospholipid efflux [GO:0033700]; plasma membrane long-chain fatty acid transport [GO:0015911]; positive regulation of cell migration [GO:0030335]; response to drug [GO:0042493]; response to oxidative stress [GO:0006979]; transmembrane transport [GO:0055085]; xenobiotic transport [GO:0042908]	GO:0005324; GO:0005524; GO:0005737; GO:0005886; GO:0005887; GO:0006855; GO:0006979; GO:0008559; GO:0015238; GO:0015431; GO:0015562; GO:0015911; GO:0016020; GO:0016323; GO:0016491; GO:0030335; GO:0033700; GO:0034040; GO:0034634; GO:0034775; GO:0042493; GO:0042908; GO:0043215; GO:0046618; GO:0046624; GO:0055085; GO:0060326; GO:1901215	0	0	0	PF00664;PF00005;	4872	m.34368	123865.75	90858.33333	1467877.75	264262.5	39696	122759.6667	1297777.75	85224.75	631839	199719.25	1.176566539
CHOYP_MTOR.2.2	P42345	m.51573	sp	MTOR_HUMAN	64.88	2537	818	16	8	2479	21	2549	0	3351	MTOR_HUMAN	reviewed	Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin and FKBP12 target 1) (Rapamycin target protein 1)	MTOR FRAP FRAP1 FRAP2 RAFT1 RAPT1	Homo sapiens (Human)	2549	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; brain development [GO:0007420]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell growth [GO:0016049]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient levels [GO:0031669]; DNA repair [GO:0006281]; energy reserve metabolic process [GO:0006112]; germ cell development [GO:0007281]; growth [GO:0040007]; heart morphogenesis [GO:0003007]; heart valve morphogenesis [GO:0003179]; long-term memory [GO:0007616]; macroautophagy [GO:0016236]; maternal process involved in female pregnancy [GO:0060135]; mRNA stabilization [GO:0048255]; multicellular organism growth [GO:0035264]; negative regulation of autophagy [GO:0010507]; negative regulation of cell size [GO:0045792]; negative regulation of cholangiocyte apoptotic process [GO:1904193]; negative regulation of iodide transmembrane transport [GO:1904213]; negative regulation of macroautophagy [GO:0016242]; negative regulation of muscle atrophy [GO:0014736]; negative regulation of NFAT protein import into nucleus [GO:0051534]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein ubiquitination [GO:0031397]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphorylation [GO:0016310]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of eating behavior [GO:1904000]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulosa cell proliferation [GO:1904197]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of myotube differentiation [GO:0010831]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron maturation [GO:0014042]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of sensory perception of pain [GO:1904058]; positive regulation of skeletal muscle hypertrophy [GO:1904206]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of transcription from RNA polymerase III promoter [GO:0045945]; positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter [GO:1901838]; positive regulation of translation [GO:0045727]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein catabolic process [GO:0030163]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of brown fat cell differentiation [GO:0090335]; regulation of carbohydrate utilization [GO:0043610]; regulation of cellular response to heat [GO:1900034]; regulation of fatty acid beta-oxidation [GO:0031998]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of GTPase activity [GO:0043087]; regulation of membrane permeability [GO:0090559]; regulation of myelination [GO:0031641]; regulation of osteoclast differentiation [GO:0045670]; regulation of protein kinase activity [GO:0045859]; regulation of response to food [GO:0032095]; response to amino acid [GO:0043200]; response to cocaine [GO:0042220]; response to insulin [GO:0032868]; response to morphine [GO:0043278]; response to nutrient [GO:0007584]; response to stress [GO:0006950]; ruffle organization [GO:0031529]; signal transduction [GO:0007165]; social behavior [GO:0035176]; spinal cord development [GO:0021510]; T cell costimulation [GO:0031295]; TOR signaling [GO:0031929]; visual learning [GO:0008542]; voluntary musculoskeletal movement [GO:0050882]; wound healing [GO:0042060]	GO:0000139; GO:0001030; GO:0001031; GO:0001032; GO:0001156; GO:0001933; GO:0001934; GO:0001938; GO:0003007; GO:0003179; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005741; GO:0005764; GO:0005765; GO:0005789; GO:0005829; GO:0005942; GO:0005979; GO:0006112; GO:0006207; GO:0006281; GO:0006468; GO:0006950; GO:0007050; GO:0007165; GO:0007281; GO:0007420; GO:0007569; GO:0007584; GO:0007616; GO:0008542; GO:0009791; GO:0010507; GO:0010592; GO:0010628; GO:0010831; GO:0012505; GO:0014042; GO:0014736; GO:0016020; GO:0016049; GO:0016236; GO:0016242; GO:0016301; GO:0016310; GO:0016605; GO:0018105; GO:0018107; GO:0021510; GO:0030163; GO:0030425; GO:0030838; GO:0031295; GO:0031397; GO:0031529; GO:0031641; GO:0031669; GO:0031929; GO:0031931; GO:0031932; GO:0031998; GO:0032095; GO:0032868; GO:0032956; GO:0035176; GO:0035264; GO:0040007; GO:0042060; GO:0042220; GO:0043022; GO:0043025; GO:0043087; GO:0043200; GO:0043278; GO:0043610; GO:0045429; GO:0045670; GO:0045727; GO:0045792; GO:0045859; GO:0045945; GO:0046777; GO:0046889; GO:0048015; GO:0048255; GO:0048661; GO:0048714; GO:0050731; GO:0050882; GO:0051219; GO:0051496; GO:0051534; GO:0051897; GO:0055013; GO:0060048; GO:0060135; GO:0060252; GO:0060999; GO:0061051; GO:0071456; GO:0090335; GO:0090559; GO:1900034; GO:1901216; GO:1901838; GO:1904000; GO:1904056; GO:1904058; GO:1904193; GO:1904197; GO:1904206; GO:1904213	0	0	0	PF11865;PF02259;PF02260;PF08771;PF00454;	4888	m.51573	134636.5	101621	83347	141601	109201	144805.5	56245	409431.5	1509876.333	22049	3.755930784
CHOYP_NEB1.1.1	Q6R891	m.35802	sp	NEB2_MOUSE	40.377	478	179	13	793	1265	432	808	9.49E-82	291	NEB2_MOUSE	reviewed	Neurabin-2 (Neurabin-II) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin)	Ppp1r9b	Mus musculus (Mouse)	817	actin cytoskeleton organization [GO:0030036]; actin filament depolymerization [GO:0030042]; actin filament organization [GO:0007015]; aging [GO:0007568]; calcium-mediated signaling [GO:0019722]; cell migration [GO:0016477]; cellular response to drug [GO:0035690]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to light stimulus [GO:0071482]; cellular response to morphine [GO:0071315]; cellular response to peptide [GO:1901653]; cerebral cortex development [GO:0021987]; dendrite development [GO:0016358]; developmental process involved in reproduction [GO:0003006]; filopodium assembly [GO:0046847]; hippocampus development [GO:0021766]; learning [GO:0007612]; male mating behavior [GO:0060179]; modulation of synaptic transmission [GO:0050804]; negative regulation of cell growth [GO:0030308]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; positive regulation of protein localization to actin cortical patch [GO:1904372]; protein localization to actin cytoskeleton [GO:1903119]; protein localization to cell periphery [GO:1990778]; regulation of cell proliferation [GO:0042127]; regulation of opioid receptor signaling pathway [GO:2000474]; regulation of protein phosphorylation [GO:0001932]; reproductive system development [GO:0061458]; response to amphetamine [GO:0001975]; response to antidepressant [GO:0036276]; response to clozapine [GO:0097338]; response to immobilization stress [GO:0035902]; response to kainic acid [GO:1904373]; response to L-phenylalanine derivative [GO:1904386]; response to nicotine [GO:0035094]; response to prostaglandin E [GO:0034695]; response to steroid hormone [GO:0048545]	GO:0001932; GO:0001975; GO:0003006; GO:0003779; GO:0004672; GO:0004864; GO:0005654; GO:0005737; GO:0005886; GO:0005912; GO:0007015; GO:0007568; GO:0007612; GO:0014069; GO:0016358; GO:0016477; GO:0019722; GO:0021766; GO:0021987; GO:0030027; GO:0030036; GO:0030042; GO:0030175; GO:0030308; GO:0030425; GO:0030426; GO:0030864; GO:0032515; GO:0032587; GO:0034695; GO:0035094; GO:0035690; GO:0035902; GO:0036276; GO:0042127; GO:0043025; GO:0044326; GO:0044327; GO:0046847; GO:0048545; GO:0050804; GO:0051015; GO:0060179; GO:0061458; GO:0071315; GO:0071364; GO:0071392; GO:0071482; GO:0090004; GO:0097338; GO:1901653; GO:1903119; GO:1904372; GO:1904373; GO:1904386; GO:1990778; GO:1990780; GO:2000474	0	0	0	PF00595;	4988	m.35802	NA	13782	87759	32629	38977	310425	30935	NA	160199	NA	3.862298124
CHOYP_NEMVEDRAFT_V1G198897.2.6	Q3SZZ2	m.4751	sp	XBP1_BOVIN	49.593	123	55	2	5	120	14	136	3.34E-28	106	XBP1_BOVIN	reviewed	"X-box-binding protein 1 (XBP-1) [Cleaved into: X-box-binding protein 1, cytoplasmic form; X-box-binding protein 1, luminal form]"	XBP1	Bos taurus (Bovine)	261	adipose tissue development [GO:0060612]; angiogenesis [GO:0001525]; cell growth [GO:0016049]; cellular response to amino acid stimulus [GO:0071230]; cellular response to fluid shear stress [GO:0071498]; cellular response to fructose stimulus [GO:0071332]; cellular response to glucose starvation [GO:0042149]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-4 [GO:0071353]; cellular response to laminar fluid shear stress [GO:0071499]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient [GO:0031670]; cellular response to oxidative stress [GO:0034599]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular triglyceride homeostasis [GO:0035356]; cholesterol homeostasis [GO:0042632]; endothelial cell proliferation [GO:0001935]; epithelial cell maturation involved in salivary gland development [GO:0060691]; exocrine pancreas development [GO:0031017]; fatty acid homeostasis [GO:0055089]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; liver development [GO:0001889]; muscle organ development [GO:0007517]; negative regulation of apoptotic process [GO:0043066]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of endoplasmic reticulum unfolded protein response [GO:1900102]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron development [GO:0048666]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of autophagy [GO:0010508]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of hepatocyte proliferation [GO:2000347]; positive regulation of histone methylation [GO:0031062]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of lactation [GO:1903489]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of plasma cell differentiation [GO:1900100]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein acetylation [GO:1901985]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of TOR signaling [GO:0032008]; positive regulation of transcription factor import into nucleus [GO:0042993]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response [GO:0006990]; protein destabilization [GO:0031648]; regulation of autophagy [GO:0010506]; response to endoplasmic reticulum stress [GO:0034976]; response to insulin-like growth factor stimulus [GO:1990418]; sterol homeostasis [GO:0055092]; transcription from RNA polymerase II promoter [GO:0006366]; ubiquitin-dependent protein catabolic process [GO:0006511]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	GO:0000122; GO:0000977; GO:0000981; GO:0001047; GO:0001158; GO:0001525; GO:0001889; GO:0001934; GO:0001935; GO:0002639; GO:0003700; GO:0005634; GO:0005737; GO:0005783; GO:0005829; GO:0006366; GO:0006511; GO:0006990; GO:0007517; GO:0010506; GO:0010508; GO:0010832; GO:0014065; GO:0016049; GO:0030176; GO:0031017; GO:0031062; GO:0031490; GO:0031648; GO:0031670; GO:0032008; GO:0032869; GO:0034599; GO:0034976; GO:0035356; GO:0035924; GO:0042149; GO:0042632; GO:0042993; GO:0043066; GO:0045348; GO:0045579; GO:0045582; GO:0045600; GO:0045944; GO:0046982; GO:0048010; GO:0048666; GO:0051024; GO:0055089; GO:0055092; GO:0060612; GO:0060691; GO:0070059; GO:0071222; GO:0071230; GO:0071332; GO:0071333; GO:0071353; GO:0071375; GO:0071498; GO:0071499; GO:1900100; GO:1900102; GO:1900103; GO:1901800; GO:1901985; GO:1902236; GO:1903489; GO:1990418; GO:2000347; GO:2000353; GO:2000778	0	0	0	PF07716;	5041	m.4748	404447.4118	399862.6154	511241.3333	355512.5333	1024721.933	213654.2857	1321401.389	711064.7857	15319009.27	398925.3182	6.663754542
CHOYP_NEMVEDRAFT_V1G236573.2.2	Q57951	m.47233	sp	Y531_METJA	29.801	151	86	6	7	150	29	166	1.29E-07	51.6	Y531_METJA	reviewed	Universal stress protein MJ0531 (USP MJ0531)	MJ0531	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)	170	response to stress [GO:0006950]	GO:0006950	0	0	0	PF00582;	5059	m.47233	72222.5	5161887.333	76406.5	43000.66667	47376	41272.5	3630415.333	110496	158054.6667	42794.5	0.737476747
CHOYP_NEMVEDRAFT_V1G236658.1.6	P72745	m.1822	sp	Y1101_SYNY3	37.864	103	62	1	51	151	6	108	4.76E-13	64.7	Y1101_SYNY3	reviewed	Universal stress protein Slr1101 (USP Slr1101)	slr1101	Synechocystis sp. (strain PCC 6803 / Kazusa)	108	response to stress [GO:0006950]	GO:0006950	0	0	0	PF00582;	5061	m.1822	NA	87116	146000	3222080	804821.5	981013	30429	874659	19313	5167600	1.328260083
CHOYP_NEMVEDRAFT_V1G236658.2.6	P72745	m.2257	sp	Y1101_SYNY3	38.835	103	61	1	51	151	6	108	8.99E-15	68.9	Y1101_SYNY3	reviewed	Universal stress protein Slr1101 (USP Slr1101)	slr1101	Synechocystis sp. (strain PCC 6803 / Kazusa)	108	response to stress [GO:0006950]	GO:0006950	0	0	0	PF00582;	5062	m.2257	NA	61208.5	149232.5	5246573.6	380694.2	340942.6667	30429	483893.75	64313.5	1747485.333	0.365494661
CHOYP_NEMVEDRAFT_V1G236658.3.6	P74148	m.24704	sp	Y1388_SYNY3	33.981	103	66	1	52	154	54	154	5.18E-15	70.9	Y1388_SYNY3	reviewed	Universal stress protein Sll1388 (USP Sll1388)	sll1388	Synechocystis sp. (strain PCC 6803 / Kazusa)	154	response to stress [GO:0006950]	GO:0006950	0	0	0	PF00582;	5063	m.24704	249479	159989.8333	182803.4	505480.4	182921.75	335568	136533.3333	151895.6667	1053411.167	1063397.429	2.14012682
CHOYP_NEMVEDRAFT_V1G236658.5.6	O07552	m.34525	sp	NHAX_BACSU	30.12	166	94	4	3	149	4	166	9.18E-15	70.9	NHAX_BACSU	reviewed	Stress response protein NhaX	nhaX yheK BSU09690	Bacillus subtilis (strain 168)	166	response to stress [GO:0006950]	GO:0006950	0	0	0	PF00582;	5064	m.34525	3647758	2066800	4876605	9299957	57645	46317	2617149.5	5506400.5	36358936	5939894	2.529915862
CHOYP_NEMVEDRAFT_V1G242153.2.4	Q57951	m.15572	sp	Y531_METJA	34.965	143	87	5	6	145	27	166	1.28E-12	64.7	Y531_METJA	reviewed	Universal stress protein MJ0531 (USP MJ0531)	MJ0531	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)	170	response to stress [GO:0006950]	GO:0006950	0	0	0	PF00582;	5082	m.15572	37794	521132	34594	36095	NA	13190970	396433	54636	14465	48929	17.41436656
CHOYP_NEMVEDRAFT_V1G242153.3.4	O07552	m.17716	sp	NHAX_BACSU	24.375	160	105	3	8	151	7	166	1.31E-10	60.1	NHAX_BACSU	reviewed	Stress response protein NhaX	nhaX yheK BSU09690	Bacillus subtilis (strain 168)	166	response to stress [GO:0006950]	GO:0006950	0	0	0	PF00582;	5083	m.17716	532078	261872	31404	1719258	34738	365047	44684	178120.5	1010793	80591.5	0.651030686
CHOYP_NEMVEDRAFT_V1G242153.4.4	Q2FXL6	m.60071	sp	Y1819_STAA8	31.818	154	85	5	12	160	5	143	2.43E-11	61.6	Y1819_STAA8	reviewed	Putative universal stress protein SAOUHSC_01819	SAOUHSC_01819	Staphylococcus aureus (strain NCTC 8325)	166	response to stress [GO:0006950]	GO:0005737; GO:0006950	0	0	0	PF00582;	5084	m.60071	1420350	632221.4444	812775.0909	2180244.077	317680.2727	341688.0909	359091.8	1149345.286	6581515.083	693967.0769	1.701500359
CHOYP_NEMVEDRAFT_V1G244537.1.3	P72745	m.7917	sp	Y1101_SYNY3	38.835	103	61	1	51	151	6	108	8.99E-15	68.9	Y1101_SYNY3	reviewed	Universal stress protein Slr1101 (USP Slr1101)	slr1101	Synechocystis sp. (strain PCC 6803 / Kazusa)	108	response to stress [GO:0006950]	GO:0006950	0	0	0	PF00582;	5086	m.7917	NA	61208.5	149232.5	5246573.6	380694.2	340942.6667	30429	483893.75	64313.5	1747485.333	0.365494661
CHOYP_NEMVEDRAFT_V1G244537.2.3	P74148	m.10401	sp	Y1388_SYNY3	28.758	153	94	4	15	156	6	154	2.15E-11	61.6	Y1388_SYNY3	reviewed	Universal stress protein Sll1388 (USP Sll1388)	sll1388	Synechocystis sp. (strain PCC 6803 / Kazusa)	154	response to stress [GO:0006950]	GO:0006950	0	0	0	PF00582;	5087	m.10401	80288.25	1448493.75	42906	708872.4	76588.66667	64732.66667	29403	171431.5	310548.3333	106489.6667	0.289589308
CHOYP_PAK1.1.1	Q08E52	m.50796	sp	PAK1_BOVIN	51.471	476	199	7	42	495	75	540	7.78E-157	459	PAK1_BOVIN	reviewed	Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (Alpha-PAK) (p21-activated kinase 1) (PAK-1) (p65-PAK)	PAK1	Bos taurus (Bovine)	544	actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; branching morphogenesis of an epithelial tube [GO:0048754]; exocytosis [GO:0006887]; negative regulation of cell proliferation involved in contact inhibition [GO:0060244]; positive regulation of cell migration [GO:0030335]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of stress fiber assembly [GO:0051496]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; wound healing [GO:0042060]	GO:0001726; GO:0001934; GO:0004674; GO:0004702; GO:0005518; GO:0005524; GO:0005737; GO:0005794; GO:0005886; GO:0005911; GO:0005925; GO:0006468; GO:0006887; GO:0006915; GO:0007409; GO:0030036; GO:0030335; GO:0031532; GO:0032587; GO:0033138; GO:0033148; GO:0042060; GO:0043234; GO:0043507; GO:0046777; GO:0048754; GO:0051496; GO:0060244; GO:0071437	0	0	0	PF00786;PF00069;	5199	m.50796	371818.7778	31814	248695.8571	117279.8571	47584.75	501868.3333	43142.33333	259073	353015.6667	194198.875	1.653584659
CHOYP_PDI23.1.1	Q67UF5	m.52419	sp	PDI23_ORYSJ	38.961	77	39	2	52	122	170	244	9.48E-06	47.8	PDI23_ORYSJ	reviewed	Protein disulfide isomerase-like 2-3 (OsPDIL2-3) (EC 5.3.4.1) (Protein disulfide isomerase-like 5-1) (OsPDIL5-1)	PDIL2-3 PDIL5-1 Os09g0451500 LOC_Os09g27830 OJ1163_C07.26 P0488D02.3	Oryza sativa subsp. japonica (Rice)	441	cell redox homeostasis [GO:0045454]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976]	GO:0003756; GO:0005576; GO:0005783; GO:0006457; GO:0034976; GO:0045454	0	0	0	PF00085;	5235	m.52419	26051	5956856	131661.5	7798984	80839	3992073.5	118609	NA	83544	167614	0.389606124
CHOYP_PDIA1.1.1	P04785	m.5297	sp	PDIA1_RAT	61.475	488	178	3	18	495	22	509	0	617	PDIA1_RAT	reviewed	Protein disulfide-isomerase (PDI) (EC 5.3.4.1) (Cellular thyroid hormone-binding protein) (Prolyl 4-hydroxylase subunit beta)	P4hb Pdia1	Rattus norvegicus (Rat)	509	cell redox homeostasis [GO:0045454]; cellular response to hypoxia [GO:0071456]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; positive regulation of viral entry into host cell [GO:0046598]; protein folding [GO:0006457]; regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902175]; response to endoplasmic reticulum stress [GO:0034976]	GO:0003756; GO:0004656; GO:0005783; GO:0005788; GO:0005793; GO:0005925; GO:0006457; GO:0009897; GO:0016222; GO:0018401; GO:0019899; GO:0034663; GO:0034976; GO:0042470; GO:0044822; GO:0045454; GO:0046598; GO:0046982; GO:0070062; GO:0071456; GO:1902175	0	0	0	PF00085;	5236	m.5297	1418696.52	1427371.708	2906920.391	2269920.917	1160875	1183863.421	1490713.5	864647.2778	3997461.32	2991380.348	1.14637553
CHOYP_PDIA3.1.1	Q8JG64	m.60223	sp	PDIA3_CHICK	58.836	464	182	6	16	473	24	484	0	547	PDIA3_CHICK	reviewed	Protein disulfide-isomerase A3 (EC 5.3.4.1) (Endoplasmic reticulum resident protein 57) (ER protein 57) (ERp57) (Glucose-regulated thiol oxidoreductase 58 kDa protein)	PDIA3 ERP57 GRP58	Gallus gallus (Chicken)	505	cell redox homeostasis [GO:0045454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976]	GO:0003756; GO:0005634; GO:0005783; GO:0005788; GO:0005925; GO:0006457; GO:0009986; GO:0034976; GO:0042470; GO:0043209; GO:0044822; GO:0045454; GO:0070062; GO:2001238	0	0	0	PF00085;	5237	m.60223	11868696.27	9824658.774	11745838.6	11490595.67	1982051.107	2228632.917	9920179.148	6182997.889	41933325.22	12148705.46	1.543615428
CHOYP_PDIA4.1.1	P13667	m.54958	sp	PDIA4_HUMAN	54.031	583	263	5	43	621	64	645	0	639	PDIA4_HUMAN	reviewed	Protein disulfide-isomerase A4 (EC 5.3.4.1) (Endoplasmic reticulum resident protein 70) (ER protein 70) (ERp70) (Endoplasmic reticulum resident protein 72) (ER protein 72) (ERp-72) (ERp72)	PDIA4 ERP70 ERP72	Homo sapiens (Human)	645	cell redox homeostasis [GO:0045454]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein secretion [GO:0009306]; response to endoplasmic reticulum stress [GO:0034976]	GO:0003756; GO:0005788; GO:0006457; GO:0009306; GO:0009986; GO:0034976; GO:0042470; GO:0044822; GO:0045454; GO:0061077	0	0	0	PF00085;	5238	m.54958	1586307.444	496688.4	2135427.545	782607.4444	664229.2857	67293	179528.75	339763.25	1205159.625	234963.7143	0.35774321
CHOYP_PDIA6.1.2	Q922R8	m.9012	sp	PDIA6_MOUSE	63.027	403	139	4	3	400	43	440	0	522	PDIA6_MOUSE	reviewed	Protein disulfide-isomerase A6 (EC 5.3.4.1) (Thioredoxin domain-containing protein 7)	Pdia6 Txndc7	Mus musculus (Mouse)	440	apoptotic cell clearance [GO:0043277]; cell redox homeostasis [GO:0045454]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976]	GO:0003756; GO:0005788; GO:0005793; GO:0005886; GO:0006457; GO:0030168; GO:0034663; GO:0034976; GO:0042470; GO:0043277; GO:0045454; GO:0070062; GO:0070527	0	0	0	PF00085;	5239	m.9012	523903.7857	580897.5	218770.1	229623.8889	897095.7143	451242.4286	251150.4444	503889.375	2967423.813	854622.0909	2.052135103
CHOYP_PHUM_PHUM071280.1.1	Q9Y6E0	m.25507	sp	STK24_HUMAN	69.146	363	92	5	8	363	28	377	1.98E-162	472	STK24_HUMAN	reviewed	Serine/threonine-protein kinase 24 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 3) (MST-3) (STE20-like kinase MST3) [Cleaved into: Serine/threonine-protein kinase 24 36 kDa subunit (Mammalian STE20-like protein kinase 3 N-terminal) (MST3/N); Serine/threonine-protein kinase 24 12 kDa subunit (Mammalian STE20-like protein kinase 3 C-terminal) (MST3/C)]	STK24 MST3 STK3	Homo sapiens (Human)	443	cellular component disassembly involved in execution phase of apoptosis [GO:0006921]; execution phase of apoptosis [GO:0097194]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; mitotic cell cycle [GO:0000278]; negative regulation of cell migration [GO:0030336]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of axon regeneration [GO:0048679]; response to hydrogen peroxide [GO:0042542]; signal transduction [GO:0007165]	GO:0000278; GO:0004672; GO:0004674; GO:0004702; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0005913; GO:0006468; GO:0006921; GO:0007165; GO:0008631; GO:0016020; GO:0030336; GO:0042542; GO:0046777; GO:0046872; GO:0048679; GO:0070062; GO:0097194; GO:0098641	0	0	0	PF00069;	5275	m.25507	246911.5	2041324	855477.3333	46377.5	2257489.75	1435030.5	825556.6667	121255.3333	287718	153497.75	0.518222441
CHOYP_PHUM_PHUM305910.1.2	O35867	m.58404	sp	NEB1_RAT	39.226	594	228	16	785	1368	433	903	1.24E-86	311	NEB1_RAT	reviewed	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (PP1bp175) (Protein phosphatase 1 regulatory subunit 9A) (p180)	Ppp1r9a	Rattus norvegicus (Rat)	1095	actin filament organization [GO:0007015]; aging [GO:0007568]; calcium-mediated signaling [GO:0019722]; cellular response to toxic substance [GO:0097237]; excitatory postsynaptic potential [GO:0060079]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of spontaneous neurotransmitter secretion [GO:1904049]; negative regulation of stress fiber assembly [GO:0051497]; neuron development [GO:0048666]; neuron projection development [GO:0031175]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of long term synaptic depression [GO:1900454]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein kinase activity [GO:0045860]; regulation of actin filament polymerization [GO:0030833]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of filopodium assembly [GO:0051489]; regulation of synapse assembly [GO:0051963]; regulation of synapse structural plasticity [GO:0051823]	GO:0005829; GO:0005856; GO:0007015; GO:0007568; GO:0008022; GO:0008157; GO:0010976; GO:0014069; GO:0015629; GO:0019722; GO:0019901; GO:0019904; GO:0030027; GO:0030054; GO:0030175; GO:0030425; GO:0030426; GO:0030833; GO:0030864; GO:0031175; GO:0031594; GO:0032403; GO:0042803; GO:0043005; GO:0043025; GO:0043197; GO:0044325; GO:0044326; GO:0045202; GO:0045860; GO:0048666; GO:0051015; GO:0051020; GO:0051489; GO:0051497; GO:0051823; GO:0051963; GO:0060079; GO:0060999; GO:0061001; GO:0097237; GO:1900272; GO:1900454; GO:1904049; GO:1990761	0	0	0	PF00595;PF07647;	5299	m.58404	NA	13782	87759	32629	38977	310425	30935	NA	160199	NA	3.862298124
CHOYP_PHUM_PHUM305910.2.2	O35867	m.64762	sp	NEB1_RAT	36.74	822	321	22	126	934	439	1074	9.89E-116	384	NEB1_RAT	reviewed	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (PP1bp175) (Protein phosphatase 1 regulatory subunit 9A) (p180)	Ppp1r9a	Rattus norvegicus (Rat)	1095	actin filament organization [GO:0007015]; aging [GO:0007568]; calcium-mediated signaling [GO:0019722]; cellular response to toxic substance [GO:0097237]; excitatory postsynaptic potential [GO:0060079]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of spontaneous neurotransmitter secretion [GO:1904049]; negative regulation of stress fiber assembly [GO:0051497]; neuron development [GO:0048666]; neuron projection development [GO:0031175]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of long term synaptic depression [GO:1900454]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein kinase activity [GO:0045860]; regulation of actin filament polymerization [GO:0030833]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of filopodium assembly [GO:0051489]; regulation of synapse assembly [GO:0051963]; regulation of synapse structural plasticity [GO:0051823]	GO:0005829; GO:0005856; GO:0007015; GO:0007568; GO:0008022; GO:0008157; GO:0010976; GO:0014069; GO:0015629; GO:0019722; GO:0019901; GO:0019904; GO:0030027; GO:0030054; GO:0030175; GO:0030425; GO:0030426; GO:0030833; GO:0030864; GO:0031175; GO:0031594; GO:0032403; GO:0042803; GO:0043005; GO:0043025; GO:0043197; GO:0044325; GO:0044326; GO:0045202; GO:0045860; GO:0048666; GO:0051015; GO:0051020; GO:0051489; GO:0051497; GO:0051823; GO:0051963; GO:0060079; GO:0060999; GO:0061001; GO:0097237; GO:1900272; GO:1900454; GO:1904049; GO:1990761	0	0	0	PF00595;PF07647;	5300	m.64762	NA	13782	87759	32629	38977	310425	30935	NA	160199	NA	3.862298124
CHOYP_PHUM_PHUM596890.1.1	Q63073	m.10990	sp	BTG1_RAT	46.584	161	81	2	1	156	11	171	4.52E-47	154	BTG1_RAT	reviewed	Protein BTG1 (Anti-proliferative factor) (B-cell translocation gene 1 protein)	Btg1	Rattus norvegicus (Rat)	171	negative regulation of cell proliferation [GO:0008285]; positive regulation of angiogenesis [GO:0045766]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of fibroblast apoptotic process [GO:2000271]; protein methylation [GO:0006479]; response to oxidative stress [GO:0006979]; response to peptide hormone [GO:0043434]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]	GO:0005634; GO:0005737; GO:0006479; GO:0006979; GO:0007283; GO:0007286; GO:0008285; GO:0019899; GO:0043434; GO:0045603; GO:0045766; GO:2000271	0	0	0	PF07742;	5329	m.10989	1082034.333	675344.4706	1160378.294	1124097.611	887140.6154	719613.9375	970006.2174	1012582.526	5398580.053	1675689.5	1.983461454
CHOYP_PLSP.2.5	H2A0M7	m.40533	sp	PLSP_PINMG	42.75	669	314	17	2	629	60	700	3.24E-140	430	PLSP_PINMG	reviewed	Peroxidase-like protein	0	Pinctada margaritifera (Black-lipped pearl oyster)	793	response to oxidative stress [GO:0006979]	GO:0004601; GO:0005576; GO:0006979; GO:0020037	0	0	0	PF03098;	5358	m.40533	52347	94873	44280	494780	356927.5	308450	32671	NA	47791	2240733	3.150913169
CHOYP_PLSP.4.5	H2A0M7	m.44386	sp	PLSP_PINMG	42.751	676	319	16	73	708	60	707	3.32E-138	431	PLSP_PINMG	reviewed	Peroxidase-like protein	0	Pinctada margaritifera (Black-lipped pearl oyster)	793	response to oxidative stress [GO:0006979]	GO:0004601; GO:0005576; GO:0006979; GO:0020037	0	0	0	PF03098;	5359	m.44386	52347	94873	44280	494780	356927.5	308450	32671	NA	47791	2240733	3.150913169
CHOYP_PNCB.1.1	Q9VQX4	m.57201	sp	PNCB_DROME	67.103	535	176	0	36	570	21	555	0	748	PNCB_DROME	reviewed	Nicotinate phosphoribosyltransferase (NAPRTase) (EC 6.3.4.21)	CG3714	Drosophila melanogaster (Fruit fly)	555	NAD biosynthetic process [GO:0009435]; nicotinate nucleotide salvage [GO:0019358]; response to oxidative stress [GO:0006979]	GO:0004514; GO:0004516; GO:0005829; GO:0006979; GO:0009435; GO:0016874; GO:0019358	PATHWAY: Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1.	0	0	PF04095;	5372	m.57201	39938.5	1267824.667	157329.5	1180542	182526	468122	147241	NA	186544.5	1303218	0.930430476
CHOYP_RAC1.1.3	Q6RUV5	m.20871	sp	RAC1_RAT	89.583	192	19	1	1	191	1	192	2.58E-128	361	RAC1_RAT	reviewed	Ras-related C3 botulinum toxin substrate 1 (p21-Rac1)	Rac1	Rattus norvegicus (Rat)	192	"actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; actin filament polymerization [GO:0030041]; anatomical structure arrangement [GO:0048532]; auditory receptor cell morphogenesis [GO:0002093]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; cell-cell junction organization [GO:0045216]; cell motility [GO:0048870]; cell proliferation [GO:0008283]; cellular response to mechanical stimulus [GO:0071260]; cerebral cortex GABAergic interneuron development [GO:0021894]; cerebral cortex radially oriented cell migration [GO:0021799]; chemotaxis [GO:0006935]; cochlea morphogenesis [GO:0090103]; dendrite morphogenesis [GO:0048813]; dopaminergic neuron differentiation [GO:0071542]; embryonic olfactory bulb interneuron precursor migration [GO:0021831]; engulfment of apoptotic cell [GO:0043652]; epithelial cell morphogenesis [GO:0003382]; G-protein coupled receptor signaling pathway [GO:0007186]; homeostasis of number of cells within a tissue [GO:0048873]; hyperosmotic response [GO:0006972]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; mast cell chemotaxis [GO:0002551]; negative regulation of interleukin-23 production [GO:0032707]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of DNA replication [GO:0045740]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to plasma membrane [GO:0072659]; Rac protein signal transduction [GO:0016601]; regulation of cell migration [GO:0030334]; regulation of cell size [GO:0008361]; regulation of fibroblast migration [GO:0010762]; regulation of neuron maturation [GO:0014041]; regulation of respiratory burst [GO:0060263]; ruffle assembly [GO:0097178]; semaphorin-plexin signaling pathway [GO:0071526]; substrate adhesion-dependent cell spreading [GO:0034446]; synaptic transmission, GABAergic [GO:0051932]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]"	GO:0000139; GO:0001891; GO:0001934; GO:0002093; GO:0002551; GO:0003382; GO:0003924; GO:0005525; GO:0005634; GO:0005737; GO:0005802; GO:0005829; GO:0005884; GO:0005925; GO:0006935; GO:0006972; GO:0007015; GO:0007186; GO:0007411; GO:0008283; GO:0008361; GO:0010592; GO:0010762; GO:0014041; GO:0016020; GO:0016601; GO:0017137; GO:0019897; GO:0019901; GO:0021799; GO:0021831; GO:0021894; GO:0030027; GO:0030032; GO:0030036; GO:0030041; GO:0030334; GO:0030838; GO:0031410; GO:0031901; GO:0032587; GO:0032707; GO:0034446; GO:0036464; GO:0042470; GO:0042826; GO:0043552; GO:0043652; GO:0045216; GO:0045453; GO:0045740; GO:0048532; GO:0048813; GO:0048870; GO:0048873; GO:0051022; GO:0051496; GO:0051668; GO:0051894; GO:0051932; GO:0060071; GO:0060263; GO:0070062; GO:0071260; GO:0071526; GO:0071542; GO:0072659; GO:0090023; GO:0090103; GO:0097178; GO:1900026	0	0	0	PF00071;	5498	m.20870	118655.25	209786.6667	76244.33333	134581.75	134381	112971.75	368000	65606.33333	119534	123376.5	1.171958369
CHOYP_RAC1.1.3	Q6RUV5	m.20871	sp	RAC1_RAT	89.583	192	19	1	1	191	1	192	2.58E-128	361	RAC1_RAT	reviewed	Ras-related C3 botulinum toxin substrate 1 (p21-Rac1)	Rac1	Rattus norvegicus (Rat)	192	"actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; actin filament polymerization [GO:0030041]; anatomical structure arrangement [GO:0048532]; auditory receptor cell morphogenesis [GO:0002093]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; cell-cell junction organization [GO:0045216]; cell motility [GO:0048870]; cell proliferation [GO:0008283]; cellular response to mechanical stimulus [GO:0071260]; cerebral cortex GABAergic interneuron development [GO:0021894]; cerebral cortex radially oriented cell migration [GO:0021799]; chemotaxis [GO:0006935]; cochlea morphogenesis [GO:0090103]; dendrite morphogenesis [GO:0048813]; dopaminergic neuron differentiation [GO:0071542]; embryonic olfactory bulb interneuron precursor migration [GO:0021831]; engulfment of apoptotic cell [GO:0043652]; epithelial cell morphogenesis [GO:0003382]; G-protein coupled receptor signaling pathway [GO:0007186]; homeostasis of number of cells within a tissue [GO:0048873]; hyperosmotic response [GO:0006972]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; mast cell chemotaxis [GO:0002551]; negative regulation of interleukin-23 production [GO:0032707]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of DNA replication [GO:0045740]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to plasma membrane [GO:0072659]; Rac protein signal transduction [GO:0016601]; regulation of cell migration [GO:0030334]; regulation of cell size [GO:0008361]; regulation of fibroblast migration [GO:0010762]; regulation of neuron maturation [GO:0014041]; regulation of respiratory burst [GO:0060263]; ruffle assembly [GO:0097178]; semaphorin-plexin signaling pathway [GO:0071526]; substrate adhesion-dependent cell spreading [GO:0034446]; synaptic transmission, GABAergic [GO:0051932]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]"	GO:0000139; GO:0001891; GO:0001934; GO:0002093; GO:0002551; GO:0003382; GO:0003924; GO:0005525; GO:0005634; GO:0005737; GO:0005802; GO:0005829; GO:0005884; GO:0005925; GO:0006935; GO:0006972; GO:0007015; GO:0007186; GO:0007411; GO:0008283; GO:0008361; GO:0010592; GO:0010762; GO:0014041; GO:0016020; GO:0016601; GO:0017137; GO:0019897; GO:0019901; GO:0021799; GO:0021831; GO:0021894; GO:0030027; GO:0030032; GO:0030036; GO:0030041; GO:0030334; GO:0030838; GO:0031410; GO:0031901; GO:0032587; GO:0032707; GO:0034446; GO:0036464; GO:0042470; GO:0042826; GO:0043552; GO:0043652; GO:0045216; GO:0045453; GO:0045740; GO:0048532; GO:0048813; GO:0048870; GO:0048873; GO:0051022; GO:0051496; GO:0051668; GO:0051894; GO:0051932; GO:0060071; GO:0060263; GO:0070062; GO:0071260; GO:0071526; GO:0071542; GO:0072659; GO:0090023; GO:0090103; GO:0097178; GO:1900026	0	0	0	PF00071;	5499	m.20871	1698017.5	239534.2222	4290323.273	793678.625	439910.5	772760.2	1746402	1726022.889	16615995.82	1605572.5	3.011038189
CHOYP_RAC1.2.3	Q6RUV5	m.23406	sp	RAC1_RAT	88.333	180	21	0	23	202	13	192	5.39E-120	340	RAC1_RAT	reviewed	Ras-related C3 botulinum toxin substrate 1 (p21-Rac1)	Rac1	Rattus norvegicus (Rat)	192	"actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; actin filament polymerization [GO:0030041]; anatomical structure arrangement [GO:0048532]; auditory receptor cell morphogenesis [GO:0002093]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; cell-cell junction organization [GO:0045216]; cell motility [GO:0048870]; cell proliferation [GO:0008283]; cellular response to mechanical stimulus [GO:0071260]; cerebral cortex GABAergic interneuron development [GO:0021894]; cerebral cortex radially oriented cell migration [GO:0021799]; chemotaxis [GO:0006935]; cochlea morphogenesis [GO:0090103]; dendrite morphogenesis [GO:0048813]; dopaminergic neuron differentiation [GO:0071542]; embryonic olfactory bulb interneuron precursor migration [GO:0021831]; engulfment of apoptotic cell [GO:0043652]; epithelial cell morphogenesis [GO:0003382]; G-protein coupled receptor signaling pathway [GO:0007186]; homeostasis of number of cells within a tissue [GO:0048873]; hyperosmotic response [GO:0006972]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; mast cell chemotaxis [GO:0002551]; negative regulation of interleukin-23 production [GO:0032707]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of DNA replication [GO:0045740]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to plasma membrane [GO:0072659]; Rac protein signal transduction [GO:0016601]; regulation of cell migration [GO:0030334]; regulation of cell size [GO:0008361]; regulation of fibroblast migration [GO:0010762]; regulation of neuron maturation [GO:0014041]; regulation of respiratory burst [GO:0060263]; ruffle assembly [GO:0097178]; semaphorin-plexin signaling pathway [GO:0071526]; substrate adhesion-dependent cell spreading [GO:0034446]; synaptic transmission, GABAergic [GO:0051932]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]"	GO:0000139; GO:0001891; GO:0001934; GO:0002093; GO:0002551; GO:0003382; GO:0003924; GO:0005525; GO:0005634; GO:0005737; GO:0005802; GO:0005829; GO:0005884; GO:0005925; GO:0006935; GO:0006972; GO:0007015; GO:0007186; GO:0007411; GO:0008283; GO:0008361; GO:0010592; GO:0010762; GO:0014041; GO:0016020; GO:0016601; GO:0017137; GO:0019897; GO:0019901; GO:0021799; GO:0021831; GO:0021894; GO:0030027; GO:0030032; GO:0030036; GO:0030041; GO:0030334; GO:0030838; GO:0031410; GO:0031901; GO:0032587; GO:0032707; GO:0034446; GO:0036464; GO:0042470; GO:0042826; GO:0043552; GO:0043652; GO:0045216; GO:0045453; GO:0045740; GO:0048532; GO:0048813; GO:0048870; GO:0048873; GO:0051022; GO:0051496; GO:0051668; GO:0051894; GO:0051932; GO:0060071; GO:0060263; GO:0070062; GO:0071260; GO:0071526; GO:0071542; GO:0072659; GO:0090023; GO:0090103; GO:0097178; GO:1900026	0	0	0	PF00071;	5500	m.23406	1645025	299650.8333	5127921.75	488300.2	153692.1667	122679	2634216.8	2088013.286	19340154	669586	3.221771895
CHOYP_RAC1.3.3	Q6RUV5	m.57018	sp	RAC1_RAT	89.583	192	19	1	15	205	1	192	2.75E-128	362	RAC1_RAT	reviewed	Ras-related C3 botulinum toxin substrate 1 (p21-Rac1)	Rac1	Rattus norvegicus (Rat)	192	"actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; actin filament polymerization [GO:0030041]; anatomical structure arrangement [GO:0048532]; auditory receptor cell morphogenesis [GO:0002093]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; cell-cell junction organization [GO:0045216]; cell motility [GO:0048870]; cell proliferation [GO:0008283]; cellular response to mechanical stimulus [GO:0071260]; cerebral cortex GABAergic interneuron development [GO:0021894]; cerebral cortex radially oriented cell migration [GO:0021799]; chemotaxis [GO:0006935]; cochlea morphogenesis [GO:0090103]; dendrite morphogenesis [GO:0048813]; dopaminergic neuron differentiation [GO:0071542]; embryonic olfactory bulb interneuron precursor migration [GO:0021831]; engulfment of apoptotic cell [GO:0043652]; epithelial cell morphogenesis [GO:0003382]; G-protein coupled receptor signaling pathway [GO:0007186]; homeostasis of number of cells within a tissue [GO:0048873]; hyperosmotic response [GO:0006972]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; mast cell chemotaxis [GO:0002551]; negative regulation of interleukin-23 production [GO:0032707]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of DNA replication [GO:0045740]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to plasma membrane [GO:0072659]; Rac protein signal transduction [GO:0016601]; regulation of cell migration [GO:0030334]; regulation of cell size [GO:0008361]; regulation of fibroblast migration [GO:0010762]; regulation of neuron maturation [GO:0014041]; regulation of respiratory burst [GO:0060263]; ruffle assembly [GO:0097178]; semaphorin-plexin signaling pathway [GO:0071526]; substrate adhesion-dependent cell spreading [GO:0034446]; synaptic transmission, GABAergic [GO:0051932]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]"	GO:0000139; GO:0001891; GO:0001934; GO:0002093; GO:0002551; GO:0003382; GO:0003924; GO:0005525; GO:0005634; GO:0005737; GO:0005802; GO:0005829; GO:0005884; GO:0005925; GO:0006935; GO:0006972; GO:0007015; GO:0007186; GO:0007411; GO:0008283; GO:0008361; GO:0010592; GO:0010762; GO:0014041; GO:0016020; GO:0016601; GO:0017137; GO:0019897; GO:0019901; GO:0021799; GO:0021831; GO:0021894; GO:0030027; GO:0030032; GO:0030036; GO:0030041; GO:0030334; GO:0030838; GO:0031410; GO:0031901; GO:0032587; GO:0032707; GO:0034446; GO:0036464; GO:0042470; GO:0042826; GO:0043552; GO:0043652; GO:0045216; GO:0045453; GO:0045740; GO:0048532; GO:0048813; GO:0048870; GO:0048873; GO:0051022; GO:0051496; GO:0051668; GO:0051894; GO:0051932; GO:0060071; GO:0060263; GO:0070062; GO:0071260; GO:0071526; GO:0071542; GO:0072659; GO:0090023; GO:0090103; GO:0097178; GO:1900026	0	0	0	PF00071;	5501	m.57018	1698017.5	239534.2222	4290323.273	793678.625	439910.5	772760.2	1746402	1726022.889	16615995.82	1605572.5	3.011038189
CHOYP_RAC2.1.1	Q6RUV5	m.25357	sp	RAC1_RAT	81.699	153	28	0	1	153	1	153	8.98E-93	270	RAC1_RAT	reviewed	Ras-related C3 botulinum toxin substrate 1 (p21-Rac1)	Rac1	Rattus norvegicus (Rat)	192	"actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; actin filament polymerization [GO:0030041]; anatomical structure arrangement [GO:0048532]; auditory receptor cell morphogenesis [GO:0002093]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; cell-cell junction organization [GO:0045216]; cell motility [GO:0048870]; cell proliferation [GO:0008283]; cellular response to mechanical stimulus [GO:0071260]; cerebral cortex GABAergic interneuron development [GO:0021894]; cerebral cortex radially oriented cell migration [GO:0021799]; chemotaxis [GO:0006935]; cochlea morphogenesis [GO:0090103]; dendrite morphogenesis [GO:0048813]; dopaminergic neuron differentiation [GO:0071542]; embryonic olfactory bulb interneuron precursor migration [GO:0021831]; engulfment of apoptotic cell [GO:0043652]; epithelial cell morphogenesis [GO:0003382]; G-protein coupled receptor signaling pathway [GO:0007186]; homeostasis of number of cells within a tissue [GO:0048873]; hyperosmotic response [GO:0006972]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; mast cell chemotaxis [GO:0002551]; negative regulation of interleukin-23 production [GO:0032707]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of DNA replication [GO:0045740]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to plasma membrane [GO:0072659]; Rac protein signal transduction [GO:0016601]; regulation of cell migration [GO:0030334]; regulation of cell size [GO:0008361]; regulation of fibroblast migration [GO:0010762]; regulation of neuron maturation [GO:0014041]; regulation of respiratory burst [GO:0060263]; ruffle assembly [GO:0097178]; semaphorin-plexin signaling pathway [GO:0071526]; substrate adhesion-dependent cell spreading [GO:0034446]; synaptic transmission, GABAergic [GO:0051932]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]"	GO:0000139; GO:0001891; GO:0001934; GO:0002093; GO:0002551; GO:0003382; GO:0003924; GO:0005525; GO:0005634; GO:0005737; GO:0005802; GO:0005829; GO:0005884; GO:0005925; GO:0006935; GO:0006972; GO:0007015; GO:0007186; GO:0007411; GO:0008283; GO:0008361; GO:0010592; GO:0010762; GO:0014041; GO:0016020; GO:0016601; GO:0017137; GO:0019897; GO:0019901; GO:0021799; GO:0021831; GO:0021894; GO:0030027; GO:0030032; GO:0030036; GO:0030041; GO:0030334; GO:0030838; GO:0031410; GO:0031901; GO:0032587; GO:0032707; GO:0034446; GO:0036464; GO:0042470; GO:0042826; GO:0043552; GO:0043652; GO:0045216; GO:0045453; GO:0045740; GO:0048532; GO:0048813; GO:0048870; GO:0048873; GO:0051022; GO:0051496; GO:0051668; GO:0051894; GO:0051932; GO:0060071; GO:0060263; GO:0070062; GO:0071260; GO:0071526; GO:0071542; GO:0072659; GO:0090023; GO:0090103; GO:0097178; GO:1900026	0	0	0	PF00071;	5502	m.25357	1354954.5	163617	2058396.333	1337945.333	1225595.5	1196689.333	198115	694359.3333	4383809.5	2992520	1.541483561
CHOYP_RAN.1.3	Q5E936	m.3468	sp	TXD12_BOVIN	49.419	172	81	2	1	168	3	172	1.19E-48	158	TXD12_BOVIN	reviewed	Thioredoxin domain-containing protein 12 (EC 1.8.4.2)	TXNDC12	Bos taurus (Bovine)	172	cell redox homeostasis [GO:0045454]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]	GO:0005788; GO:0015037; GO:0019153; GO:0045454; GO:1902236	0	0	0	0	5512	m.3467	279512.5	506402.4286	649826.7143	943111.7778	56202.83333	173328.6	487011.6667	198655.3866	1350400.714	386317.4286	1.065976932
CHOYP_RAN.1.3	Q5E936	m.3468	sp	TXD12_BOVIN	49.419	172	81	2	1	168	3	172	1.19E-48	158	TXD12_BOVIN	reviewed	Thioredoxin domain-containing protein 12 (EC 1.8.4.2)	TXNDC12	Bos taurus (Bovine)	172	cell redox homeostasis [GO:0045454]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]	GO:0005788; GO:0015037; GO:0019153; GO:0045454; GO:1902236	0	0	0	0	5513	m.3468	218817	698598	126286	34363	307466	142440	76101	502443	1253623	70684.5	1.476179873
CHOYP_RGD1561408.1.2	P15941	m.4308	sp	MUC1_HUMAN	38.027	902	422	38	1771	2617	127	946	4.09E-46	188	MUC1_HUMAN	reviewed	Mucin-1 (MUC-1) (Breast carcinoma-associated antigen DF3) (Cancer antigen 15-3) (CA 15-3) (Carcinoma-associated mucin) (Episialin) (H23AG) (Krebs von den Lungen-6) (KL-6) (PEMT) (Peanut-reactive urinary mucin) (PUM) (Polymorphic epithelial mucin) (PEM) (Tumor-associated epithelial membrane antigen) (EMA) (Tumor-associated mucin) (CD antigen CD227) [Cleaved into: Mucin-1 subunit alpha (MUC1-NT) (MUC1-alpha); Mucin-1 subunit beta (MUC1-beta) (MUC1-CT)]	MUC1 PUM	Homo sapiens (Human)	1255	"DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of transcription by competitive promoter binding [GO:0010944]; O-glycan processing [GO:0016266]; positive regulation of histone H4 acetylation [GO:0090240]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; regulation of transcription from RNA polymerase II promoter in response to stress [GO:0043618]"	GO:0000790; GO:0000978; GO:0002039; GO:0003712; GO:0005615; GO:0005796; GO:0005887; GO:0006977; GO:0006978; GO:0010944; GO:0016266; GO:0016324; GO:0031982; GO:0033629; GO:0036003; GO:0043618; GO:0070062; GO:0090240; GO:1902166	0	0	0	PF01390;	5548	m.4308	354959	446327.875	461376.5385	1029962.385	524334.5	798390.5	1087654.636	897699	844591.6364	364821.75	1.417541285
CHOYP_RGD1561408.2.2	P15941	m.49667	sp	MUC1_HUMAN	36.92	539	276	15	176	661	127	654	4.32E-28	127	MUC1_HUMAN	reviewed	Mucin-1 (MUC-1) (Breast carcinoma-associated antigen DF3) (Cancer antigen 15-3) (CA 15-3) (Carcinoma-associated mucin) (Episialin) (H23AG) (Krebs von den Lungen-6) (KL-6) (PEMT) (Peanut-reactive urinary mucin) (PUM) (Polymorphic epithelial mucin) (PEM) (Tumor-associated epithelial membrane antigen) (EMA) (Tumor-associated mucin) (CD antigen CD227) [Cleaved into: Mucin-1 subunit alpha (MUC1-NT) (MUC1-alpha); Mucin-1 subunit beta (MUC1-beta) (MUC1-CT)]	MUC1 PUM	Homo sapiens (Human)	1255	"DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of transcription by competitive promoter binding [GO:0010944]; O-glycan processing [GO:0016266]; positive regulation of histone H4 acetylation [GO:0090240]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; regulation of transcription from RNA polymerase II promoter in response to stress [GO:0043618]"	GO:0000790; GO:0000978; GO:0002039; GO:0003712; GO:0005615; GO:0005796; GO:0005887; GO:0006977; GO:0006978; GO:0010944; GO:0016266; GO:0016324; GO:0031982; GO:0033629; GO:0036003; GO:0043618; GO:0070062; GO:0090240; GO:1902166	0	0	0	PF01390;	5549	m.49667	591733	390180	1122877.6	53477.5	307085.5	3677619	3409288.333	2962771.667	869184	111951	4.474333418
CHOYP_RL40.1.7	P74148	m.3623	sp	Y1388_SYNY3	27.152	151	100	2	8	149	5	154	1.16E-10	60.5	Y1388_SYNY3	reviewed	Universal stress protein Sll1388 (USP Sll1388)	sll1388	Synechocystis sp. (strain PCC 6803 / Kazusa)	154	response to stress [GO:0006950]	GO:0006950	0	0	0	PF00582;	5657	m.3623	87501.33333	1410777.75	489660	85239.33333	1345362	336613.6667	124811.5	240278	635072.3333	1690509.25	0.885548913
CHOYP_RNP1B.1.1	P04792	m.59889	sp	HSPB1_HUMAN	36.145	83	52	1	46	127	89	171	9.52E-09	54.7	HSPB1_HUMAN	reviewed	Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27)	HSPB1 HSP27 HSP28	Homo sapiens (Human)	205	cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028	0	0	0	PF00011;	5723	m.59889	1996542	25739	171339.5	665833.5	17751	388418.5	80537.5	6428505	591267.3333	768276.25	2.869800582
CHOYP_RNP1B.1.1	P04792	m.59889	sp	HSPB1_HUMAN	36.145	83	52	1	46	127	89	171	9.52E-09	54.7	HSPB1_HUMAN	reviewed	Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27)	HSPB1 HSP27 HSP28	Homo sapiens (Human)	205	cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028	0	0	0	PF00011;	5724	m.59893	636340	340809.8333	7943169.909	362777.6667	568209	237382.25	5959749.143	1408708.4	1734680.25	4352681.556	1.389988397
CHOYP_RNP1B.1.1	P04792	m.59893	sp	HSPB1_HUMAN	37.838	74	45	1	28	100	95	168	1.34E-11	61.2	HSPB1_HUMAN	reviewed	Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27)	HSPB1 HSP27 HSP28	Homo sapiens (Human)	205	cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028	0	0	0	PF00011;	5723	m.59889	1996542	25739	171339.5	665833.5	17751	388418.5	80537.5	6428505	591267.3333	768276.25	2.869800582
CHOYP_RNP1B.1.1	P04792	m.59893	sp	HSPB1_HUMAN	37.838	74	45	1	28	100	95	168	1.34E-11	61.2	HSPB1_HUMAN	reviewed	Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27)	HSPB1 HSP27 HSP28	Homo sapiens (Human)	205	cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028	0	0	0	PF00011;	5724	m.59893	636340	340809.8333	7943169.909	362777.6667	568209	237382.25	5959749.143	1408708.4	1734680.25	4352681.556	1.389988397
CHOYP_RS21.1.4	O14463	m.13400	sp	TRX1_SCHPO	53.922	102	47	0	1	102	1	102	6.30E-35	118	TRX1_SCHPO	reviewed	Thioredoxin-1 (TR-1) (Trx-1)	trx1 trx2 SPAC7D4.07c	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	103	"cell redox homeostasis [GO:0045454]; cellular response to reactive oxygen species [GO:0034614]; glycerol ether metabolic process [GO:0006662]; hydrogen peroxide catabolic process [GO:0042744]; L-methionine biosynthetic process from methionine sulphoxide [GO:1990355]; positive regulation of cellular response to oxidative stress [GO:1900409]; protein folding [GO:0006457]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]"	GO:0005634; GO:0005737; GO:0005829; GO:0006457; GO:0006662; GO:0015035; GO:0016209; GO:0016671; GO:0019379; GO:0034614; GO:0042744; GO:0045454; GO:1900409; GO:1990355	0	0	0	PF00085;	5827	m.13400	131849.3333	734266	236332	378741.3333	1644346	1438813	434611.5	122780	344496.6667	24489965.45	8.584344593
CHOYP_RS6.3.12	Q99MQ3	m.5754	sp	PINK1_MOUSE	35.749	414	221	8	117	521	128	505	3.53E-75	254	PINK1_MOUSE	reviewed	"Serine/threonine-protein kinase PINK1, mitochondrial (EC 2.7.11.1) (BRPK) (PTEN-induced putative kinase protein 1)"	Pink1	Mus musculus (Mouse)	580	"cellular response to hypoxia [GO:0071456]; cellular response to oxidative stress [GO:0034599]; cellular response to toxic substance [GO:0097237]; establishment of protein localization to mitochondrion [GO:0072655]; intracellular signal transduction [GO:0035556]; maintenance of protein location in mitochondrion [GO:0072656]; mitochondrion organization [GO:0007005]; mitophagy [GO:0000422]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of autophagosome assembly [GO:1902902]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway [GO:1903384]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide [GO:1903751]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mitochondrial fission [GO:0090258]; negative regulation of mitophagy [GO:1903147]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced cell death [GO:1903202]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; peptidyl-serine autophosphorylation [GO:0036289]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of catecholamine secretion [GO:0033605]; positive regulation of cristae formation [GO:1903852]; positive regulation of dopamine secretion [GO:0033603]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of mitochondrial electron transport, NADH to ubiquinone [GO:1902958]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of synaptic transmission, dopaminergic [GO:0032226]; positive regulation of translation [GO:0045727]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of hydrogen peroxide metabolic process [GO:0010310]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mitochondrion organization [GO:0010821]; regulation of neuron apoptotic process [GO:0043523]; regulation of oxidative phosphorylation [GO:0002082]; regulation of protein complex assembly [GO:0043254]; regulation of protein targeting to mitochondrion [GO:1903214]; regulation of protein ubiquitination [GO:0031396]; regulation of reactive oxygen species metabolic process [GO:2000377]; respiratory electron transport chain [GO:0022904]; response to oxidative stress [GO:0006979]; response to stress [GO:0006950]"	GO:0000287; GO:0000422; GO:0000785; GO:0001934; GO:0002020; GO:0002082; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005739; GO:0005741; GO:0005742; GO:0005743; GO:0005758; GO:0005829; GO:0005856; GO:0006468; GO:0006950; GO:0006979; GO:0007005; GO:0010310; GO:0010629; GO:0010821; GO:0010857; GO:0016020; GO:0016239; GO:0016242; GO:0016301; GO:0016567; GO:0018105; GO:0022904; GO:0030424; GO:0031307; GO:0031396; GO:0031625; GO:0031932; GO:0032226; GO:0033138; GO:0033603; GO:0033605; GO:0034599; GO:0035307; GO:0035556; GO:0036289; GO:0043123; GO:0043254; GO:0043422; GO:0043523; GO:0043524; GO:0044297; GO:0045727; GO:0048471; GO:0050821; GO:0051091; GO:0051881; GO:0055131; GO:0071456; GO:0072655; GO:0072656; GO:0090141; GO:0090200; GO:0090258; GO:0097237; GO:0097449; GO:0098779; GO:1901727; GO:1902902; GO:1902958; GO:1903147; GO:1903202; GO:1903214; GO:1903298; GO:1903384; GO:1903751; GO:1903852; GO:1903955; GO:2000377; GO:2000378	0	0	0	PF00069;	5899	m.5755	222333.6667	10068763.57	65457.95	106437.8571	18187961	7527201.75	516518.6	11119337.4	411293.75	56527.77381	0.685173668
CHOYP_RSMB.2.2	P04792	m.37626	sp	HSPB1_HUMAN	38.667	75	43	2	161	233	95	168	3.82E-10	60.8	HSPB1_HUMAN	reviewed	Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27)	HSPB1 HSP27 HSP28	Homo sapiens (Human)	205	cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; movement of cell or subcellular component [GO:0006928]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mRNA stability [GO:0043488]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	GO:0000502; GO:0001895; GO:0005080; GO:0005615; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0006446; GO:0006469; GO:0006928; GO:0006986; GO:0008426; GO:0009615; GO:0010506; GO:0019901; GO:0030018; GO:0031012; GO:0032731; GO:0035556; GO:0035924; GO:0038033; GO:0042535; GO:0042802; GO:0043066; GO:0043122; GO:0043130; GO:0043488; GO:0043536; GO:0044822; GO:0045766; GO:0048010; GO:0070062; GO:0070527; GO:1902176; GO:2001028	0	0	0	PF00011;	5940	m.37626	651414.5556	337618.1	6317623.786	378199.4438	467184	338760.75	3826765.727	2681237.5	1244984.25	2706129.875	1.324561491
CHOYP_RTJK.3.3	O14463	m.35968	sp	TRX1_SCHPO	53.922	102	47	0	1	102	1	102	6.30E-35	118	TRX1_SCHPO	reviewed	Thioredoxin-1 (TR-1) (Trx-1)	trx1 trx2 SPAC7D4.07c	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	103	"cell redox homeostasis [GO:0045454]; cellular response to reactive oxygen species [GO:0034614]; glycerol ether metabolic process [GO:0006662]; hydrogen peroxide catabolic process [GO:0042744]; L-methionine biosynthetic process from methionine sulphoxide [GO:1990355]; positive regulation of cellular response to oxidative stress [GO:1900409]; protein folding [GO:0006457]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]"	GO:0005634; GO:0005737; GO:0005829; GO:0006457; GO:0006662; GO:0015035; GO:0016209; GO:0016671; GO:0019379; GO:0034614; GO:0042744; GO:0045454; GO:1900409; GO:1990355	0	0	0	PF00085;	5953	m.35968	131849.3333	734266	236332	378741.3333	1644346	1438813	434611.5	122780	344496.6667	24489965.45	8.584344593
CHOYP_SC31A.1.2	O57521	m.8241	sp	HS90B_DANRE	76.718	262	56	2	1	258	465	725	7.55E-140	412	HS90B_DANRE	reviewed	Heat shock protein HSP 90-beta	hsp90ab1 hsp90b	Danio rerio (Zebrafish) (Brachydanio rerio)	725	blood vessel development [GO:0001568]; leukocyte migration [GO:0050900]; muscle organ development [GO:0007517]; protein folding [GO:0006457]; response to estrogen [GO:0043627]; response to stress [GO:0006950]	GO:0001568; GO:0005524; GO:0005634; GO:0005737; GO:0006457; GO:0006950; GO:0007517; GO:0043627; GO:0050900	0	0	0	PF02518;PF00183;	5990	m.8240	9164404.2	1361520.667	116619.3333	185248.3333	1829547	9327987.6	1016510.25	4068249	527168.6667	15804239.17	2.428958677
CHOYP_SC31A.1.2	O57521	m.8241	sp	HS90B_DANRE	76.718	262	56	2	1	258	465	725	7.55E-140	412	HS90B_DANRE	reviewed	Heat shock protein HSP 90-beta	hsp90ab1 hsp90b	Danio rerio (Zebrafish) (Brachydanio rerio)	725	blood vessel development [GO:0001568]; leukocyte migration [GO:0050900]; muscle organ development [GO:0007517]; protein folding [GO:0006457]; response to estrogen [GO:0043627]; response to stress [GO:0006950]	GO:0001568; GO:0005524; GO:0005634; GO:0005737; GO:0006457; GO:0006950; GO:0007517; GO:0043627; GO:0050900	0	0	0	PF02518;PF00183;	5991	m.8241	9826332.222	19181290.6	18316325.92	4030164.375	4402794.545	8289014.429	19269643.59	5099571.583	107212864.7	217946.0909	2.51249659
CHOYP_SDHC.1.1	Q8LGG8	m.31277	sp	USPAL_ARATH	30.769	91	62	1	2	92	70	159	2.01E-11	60.1	USPAL_ARATH	reviewed	Universal stress protein A-like protein	At3g01520 F4P13.7	Arabidopsis thaliana (Mouse-ear cress)	175	response to stress [GO:0006950]	GO:0005886; GO:0006950; GO:0016208	0	0	0	PF00582;	6011	m.31276	370478.2	428105.6667	7739387.286	140654.75	989035.8	403993	476930.2	326927.6	813003.5	279494	0.237942573
CHOYP_SDHC.1.1	Q8LGG8	m.31277	sp	USPAL_ARATH	30.769	91	62	1	2	92	70	159	2.01E-11	60.1	USPAL_ARATH	reviewed	Universal stress protein A-like protein	At3g01520 F4P13.7	Arabidopsis thaliana (Mouse-ear cress)	175	response to stress [GO:0006950]	GO:0005886; GO:0006950; GO:0016208	0	0	0	PF00582;	6012	m.31277	9392793.75	9362676.167	3288374.556	13621669.58	7987565.111	12743882.11	6355402.545	9557912.417	47197799.83	18264473	2.156078602
CHOYP_SFPQ.1.1	Q8VIJ6	m.15746	sp	SFPQ_MOUSE	53.986	276	127	0	137	412	283	558	2.63E-99	317	SFPQ_MOUSE	reviewed	"Splicing factor, proline- and glutamine-rich (DNA-binding p52/p100 complex, 100 kDa subunit) (Polypyrimidine tract-binding protein-associated-splicing factor) (PSF) (PTB-associated-splicing factor)"	Sfpq Psf	Mus musculus (Mouse)	699	"alternative mRNA splicing, via spliceosome [GO:0000380]; cellular response to DNA damage stimulus [GO:0006974]; chromosome organization [GO:0051276]; double-strand break repair via homologous recombination [GO:0000724]; histone H3 deacetylation [GO:0070932]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of sister chromatid cohesion [GO:0045876]; regulation of cell cycle [GO:0051726]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]"	GO:0000122; GO:0000166; GO:0000380; GO:0000724; GO:0000785; GO:0000976; GO:0000980; GO:0001047; GO:0003682; GO:0005634; GO:0005654; GO:0005737; GO:0006351; GO:0006974; GO:0016363; GO:0042382; GO:0042752; GO:0042754; GO:0042826; GO:0044212; GO:0044822; GO:0045876; GO:0045892; GO:0048511; GO:0051276; GO:0051726; GO:0070932; GO:0090575; GO:1902177	0	0	0	PF08075;PF00076;	6045	m.15746	702141.75	5968319.625	3565680.667	693003.8571	240771.2222	572577.5	13249886.14	2090472.3	32003783.67	1434927.167	4.418264365
CHOYP_SMAD3.1.1	P84025	m.51679	sp	SMAD3_RAT	76.941	425	87	3	1	414	1	425	0	674	SMAD3_RAT	reviewed	Mothers against decapentaplegic homolog 3 (MAD homolog 3) (Mad3) (Mothers against DPP homolog 3) (SMAD family member 3) (SMAD 3) (Smad3)	Smad3 Madh3	Rattus norvegicus (Rat)	425	"activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097296]; canonical Wnt signaling pathway [GO:0060070]; cell-cell junction organization [GO:0045216]; cell cycle arrest [GO:0007050]; developmental growth [GO:0048589]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic foregut morphogenesis [GO:0048617]; embryonic pattern specification [GO:0009880]; endoderm development [GO:0007492]; evasion or tolerance of host defenses by virus [GO:0019049]; extrinsic apoptotic signaling pathway [GO:0097191]; heart looping [GO:0001947]; immune response [GO:0006955]; immune system development [GO:0002520]; intracellular signal transduction [GO:0035556]; in utero embryonic development [GO:0001701]; lens fiber cell differentiation [GO:0070306]; liver development [GO:0001889]; mesoderm formation [GO:0001707]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell proliferation [GO:0008285]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of inflammatory response [GO:0050728]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of osteoblast proliferation [GO:0033689]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of wound healing [GO:0061045]; nodal signaling pathway [GO:0038092]; osteoblast development [GO:0002076]; paraxial mesoderm morphogenesis [GO:0048340]; pericardium development [GO:0060039]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of bone mineralization [GO:0030501]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of catenin import into nucleus [GO:0035413]; positive regulation of cell migration [GO:0030335]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of extracellular matrix assembly [GO:1901203]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of transcription factor import into nucleus [GO:0042993]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transforming growth factor beta3 production [GO:0032916]; protein stabilization [GO:0050821]; regulation of binding [GO:0051098]; regulation of epithelial cell proliferation [GO:0050678]; regulation of immune response [GO:0050776]; regulation of striated muscle tissue development [GO:0016202]; regulation of transforming growth factor beta2 production [GO:0032909]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; response to hypoxia [GO:0001666]; signal transduction involved in regulation of gene expression [GO:0023019]; SMAD protein complex assembly [GO:0007183]; SMAD protein signal transduction [GO:0060395]; somitogenesis [GO:0001756]; T cell activation [GO:0042110]; thyroid gland development [GO:0030878]; transcription, DNA-templated [GO:0006351]; transdifferentiation [GO:0060290]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transport [GO:0006810]; ureteric bud development [GO:0001657]"	GO:0000122; GO:0000790; GO:0000978; GO:0000983; GO:0000987; GO:0000988; GO:0001657; GO:0001666; GO:0001701; GO:0001707; GO:0001756; GO:0001889; GO:0001933; GO:0001947; GO:0002076; GO:0002520; GO:0003677; GO:0003700; GO:0005634; GO:0005637; GO:0005654; GO:0005667; GO:0005737; GO:0005886; GO:0006351; GO:0006810; GO:0006919; GO:0006955; GO:0007050; GO:0007179; GO:0007183; GO:0007492; GO:0008013; GO:0008134; GO:0008270; GO:0008285; GO:0009880; GO:0010694; GO:0010718; GO:0016202; GO:0017015; GO:0019049; GO:0019899; GO:0023019; GO:0030308; GO:0030335; GO:0030501; GO:0030618; GO:0030878; GO:0031490; GO:0032332; GO:0032731; GO:0032909; GO:0032916; GO:0033689; GO:0035413; GO:0035556; GO:0038092; GO:0042110; GO:0042177; GO:0042993; GO:0043066; GO:0043234; GO:0043235; GO:0043565; GO:0045216; GO:0045599; GO:0045668; GO:0045930; GO:0045944; GO:0046332; GO:0048340; GO:0048589; GO:0048617; GO:0048701; GO:0050678; GO:0050728; GO:0050776; GO:0050821; GO:0050927; GO:0051098; GO:0051496; GO:0051894; GO:0060039; GO:0060070; GO:0060290; GO:0060395; GO:0061045; GO:0070306; GO:0071141; GO:0071144; GO:0090263; GO:0097191; GO:0097296; GO:1901203	0	0	0	PF03165;PF03166;	6084	m.51679	197607	440337	30815	323514.25	443263	131741	72672	41552	1320392	89663.5	1.153590165
CHOYP_SMP_049250.1.1	P42930	m.1835	sp	HSPB1_RAT	32.71	107	70	2	15	119	67	173	5.31E-08	55.1	HSPB1_RAT	reviewed	Heat shock protein beta-1 (HspB1) (Heat shock 27 kDa protein) (HSP 27)	Hspb1 Hsp27	Rattus norvegicus (Rat)	206	aging [GO:0007568]; cellular response to butyrate [GO:1903545]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-11 [GO:0071348]; female pregnancy [GO:0007565]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced cell death [GO:1903202]; positive regulation of neuron projection development [GO:0010976]; response to angiotensin [GO:1990776]; response to ischemia [GO:0002931]; response to muscle stretch [GO:0035994]	GO:0000502; GO:0002931; GO:0005634; GO:0005737; GO:0005819; GO:0005886; GO:0007565; GO:0007568; GO:0010976; GO:0030424; GO:0030425; GO:0031430; GO:0031674; GO:0035994; GO:0043066; GO:0043130; GO:0043204; GO:0045202; GO:0070301; GO:0071348; GO:0097512; GO:0098839; GO:1903202; GO:1903545; GO:1990776	0	0	0	PF00011;	6101	m.1835	150372	1061472	56760	1460974	15160	131588.5	1822599	21110	39365	431946	0.891381436
CHOYP_SMUF2.1.1	P00523	m.14325	sp	SRC_CHICK	57.983	476	190	5	29	503	66	532	0	575	SRC_CHICK	reviewed	Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)	SRC	Gallus gallus (Chicken)	533	angiotensin-activated signaling pathway involved in heart process [GO:0086098]; bone resorption [GO:0045453]; cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell migration [GO:0016477]; cellular response to fluid shear stress [GO:0071498]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to reactive oxygen species [GO:0034614]; central nervous system development [GO:0007417]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; intracellular estrogen receptor signaling pathway [GO:0030520]; intracellular signal transduction [GO:0035556]; negative regulation of anoikis [GO:2000811]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of protein homooligomerization [GO:0032463]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; oogenesis [GO:0048477]; osteoclast development [GO:0036035]; peptidyl-tyrosine autophosphorylation [GO:0038083]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; progesterone receptor signaling pathway [GO:0050847]; protein destabilization [GO:0031648]; regulation of caveolin-mediated endocytosis [GO:2001286]; regulation of cell-cell adhesion [GO:0022407]; regulation of cell cycle [GO:0051726]; regulation of cell projection assembly [GO:0060491]; regulation of cell proliferation [GO:0042127]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of podosome assembly [GO:0071801]; regulation of protein binding [GO:0043393]; response to interleukin-1 [GO:0070555]; stress fiber assembly [GO:0043149]; substrate adhesion-dependent cell spreading [GO:0034446]; transforming growth factor beta receptor signaling pathway [GO:0007179]; uterus development [GO:0060065]	GO:0004713; GO:0004715; GO:0005524; GO:0005634; GO:0005743; GO:0005764; GO:0005770; GO:0005829; GO:0005884; GO:0005901; GO:0007049; GO:0007155; GO:0007173; GO:0007179; GO:0007229; GO:0007417; GO:0010008; GO:0010634; GO:0016477; GO:0019903; GO:0020037; GO:0022407; GO:0030520; GO:0030900; GO:0031234; GO:0031648; GO:0032211; GO:0032463; GO:0032587; GO:0033146; GO:0034446; GO:0034614; GO:0035556; GO:0036035; GO:0036120; GO:0038083; GO:0042127; GO:0043149; GO:0043154; GO:0043393; GO:0045087; GO:0045453; GO:0048008; GO:0048013; GO:0048471; GO:0048477; GO:0050847; GO:0051427; GO:0051726; GO:0051897; GO:0051902; GO:0051974; GO:0060065; GO:0060491; GO:0070062; GO:0070374; GO:0070555; GO:0070851; GO:0071498; GO:0071801; GO:0071803; GO:0071902; GO:0086098; GO:0090263; GO:2000394; GO:2000641; GO:2000811; GO:2001237; GO:2001243; GO:2001286	0	0	0	PF07714;PF00017;PF00018;	6149	m.14325	524788.6667	471083.5	3185989	208675.8571	755066.5	107169.1667	478132.5714	66267.66667	1700375.167	378622.5	0.530660215
CHOYP_SNF1A.1.1	P54646	m.52779	sp	AAPK2_HUMAN	63.621	580	175	9	1	572	1	552	0	735	AAPK2_HUMAN	reviewed	5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK subunit alpha-2) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31)	PRKAA2 AMPK AMPK2	Homo sapiens (Human)	552	"carnitine shuttle [GO:0006853]; cell cycle arrest [GO:0007050]; cellular response to drug [GO:0035690]; cellular response to glucose starvation [GO:0042149]; cellular response to nutrient levels [GO:0031669]; cellular response to prostaglandin E stimulus [GO:0071380]; cholesterol biosynthetic process [GO:0006695]; fatty acid biosynthetic process [GO:0006633]; fatty acid homeostasis [GO:0055089]; glucose homeostasis [GO:0042593]; histone-serine phosphorylation [GO:0035404]; intracellular signal transduction [GO:0035556]; lipid biosynthetic process [GO:0008610]; macroautophagy [GO:0016236]; negative regulation of apoptotic process [GO:0043066]; negative regulation of TOR signaling [GO:0032007]; positive regulation of autophagy [GO:0010508]; positive regulation of glycolytic process [GO:0045821]; positive regulation of macroautophagy [GO:0016239]; protein phosphorylation [GO:0006468]; regulation of circadian rhythm [GO:0042752]; regulation of energy homeostasis [GO:2000505]; regulation of fatty acid biosynthetic process [GO:0042304]; regulation of macroautophagy [GO:0016241]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription, DNA-templated [GO:0006355]; response to muscle activity [GO:0014850]; response to stress [GO:0006950]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; transcription, DNA-templated [GO:0006351]; Wnt signaling pathway [GO:0016055]"	GO:0003682; GO:0004672; GO:0004674; GO:0004679; GO:0004712; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006351; GO:0006355; GO:0006468; GO:0006633; GO:0006695; GO:0006853; GO:0006950; GO:0007050; GO:0007165; GO:0008610; GO:0010508; GO:0014850; GO:0016055; GO:0016236; GO:0016239; GO:0016241; GO:0031588; GO:0031669; GO:0032007; GO:0035174; GO:0035404; GO:0035556; GO:0035690; GO:0042149; GO:0042304; GO:0042593; GO:0042752; GO:0043066; GO:0045821; GO:0046872; GO:0047322; GO:0048511; GO:0050405; GO:0055089; GO:0071380; GO:1901796; GO:2000505	0	0	0	PF16579;PF00069;	6150	m.52779	38782.33333	166034	517031.875	210491.1667	352785.3333	381815	100647.75	75492.5	3070035.4	148944.25	2.938963725
CHOYP_SODM.1.2	P04179	m.45531	sp	SODM_HUMAN	63.182	220	79	2	6	224	2	220	3.23E-102	298	SODM_HUMAN	reviewed	"Superoxide dismutase [Mn], mitochondrial (EC 1.15.1.1)"	SOD2	Homo sapiens (Human)	222	age-dependent response to reactive oxygen species [GO:0001315]; negative regulation of cell proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; oxygen homeostasis [GO:0032364]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to reactive oxygen species [GO:0000302]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]; vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure [GO:0003069]	GO:0000302; GO:0000303; GO:0001315; GO:0001836; GO:0003069; GO:0004784; GO:0005739; GO:0005759; GO:0006357; GO:0006801; GO:0008217; GO:0008285; GO:0019430; GO:0030145; GO:0032364; GO:0042802; GO:0043524; GO:0051289; GO:0070062; GO:1902176	0	0	0	PF02777;PF00081;	6155	m.45530	78490.66667	205071	1617600.75	761757.5	19247.5	55224.5	179952	489340.6667	436601.75	183744	0.501409013
CHOYP_STIP1.1.2	P31948	m.12856	sp	STIP1_HUMAN	52.065	557	243	5	12	564	7	543	0	550	STIP1_HUMAN	reviewed	Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (Renal carcinoma antigen NY-REN-11) (Transformation-sensitive protein IEF SSP 3521)	STIP1	Homo sapiens (Human)	543	response to stress [GO:0006950]	GO:0005634; GO:0005794; GO:0006950; GO:0043209; GO:0043234; GO:0044822	0	0	0	PF13414;PF07719;PF13181;	6202	m.12856	277224.5	239394.2857	564827.6	542207.6923	112510.4	1514133	336436.5833	1347760.615	276059.2143	9033543.176	7.204347714
CHOYP_STIP1.2.2	P31948	m.54723	sp	STIP1_HUMAN	52.065	557	243	5	24	576	7	543	0	551	STIP1_HUMAN	reviewed	Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (Renal carcinoma antigen NY-REN-11) (Transformation-sensitive protein IEF SSP 3521)	STIP1	Homo sapiens (Human)	543	response to stress [GO:0006950]	GO:0005634; GO:0005794; GO:0006950; GO:0043209; GO:0043234; GO:0044822	0	0	0	PF13414;PF07719;PF13181;	6203	m.54722	84040.75	35006.4	90229	139432.5	71744.66667	180578	279015.4	617401.3333	487972.5	292924	4.418781253
CHOYP_STIP1.2.2	P31948	m.54723	sp	STIP1_HUMAN	52.065	557	243	5	24	576	7	543	0	551	STIP1_HUMAN	reviewed	Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (Renal carcinoma antigen NY-REN-11) (Transformation-sensitive protein IEF SSP 3521)	STIP1	Homo sapiens (Human)	543	response to stress [GO:0006950]	GO:0005634; GO:0005794; GO:0006950; GO:0043209; GO:0043234; GO:0044822	0	0	0	PF13414;PF07719;PF13181;	6204	m.54723	277224.5	239394.2857	564827.6	542207.6923	112510.4	1514133	336436.5833	1347760.615	276059.2143	9033543.176	7.204347714
CHOYP_STK24.1.1	Q9Z2W1	m.13301	sp	STK25_MOUSE	65.625	416	122	9	9	419	13	412	1.88E-177	505	STK25_MOUSE	reviewed	Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response kinase 1) (SOK-1) (Ste20/oxidant stress response kinase 1)	Stk25 Sok1	Mus musculus (Mouse)	426	establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Golgi localization [GO:0051645]; Golgi reassembly [GO:0090168]; intrinsic apoptotic signaling pathway in response to hydrogen peroxide [GO:0036481]; positive regulation of axonogenesis [GO:0050772]; positive regulation of stress-activated MAPK cascade [GO:0032874]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; response to hydrogen peroxide [GO:0042542]	GO:0000139; GO:0004702; GO:0005524; GO:0005737; GO:0006468; GO:0007163; GO:0032874; GO:0036481; GO:0042542; GO:0042803; GO:0046777; GO:0046872; GO:0050772; GO:0051645; GO:0051683; GO:0070062; GO:0090168	0	0	0	PF00069;	6205	m.13301	246911.5	2041324	855477.3333	46377.5	2257489.75	1435030.5	825556.6667	121255.3333	287718	153497.75	0.518222441
CHOYP_STK39.1.1	Q9UEW8	m.44512	sp	STK39_HUMAN	63.441	93	33	1	1	92	453	545	6.08E-32	119	STK39_HUMAN	reviewed	STE20/SPS1-related proline-alanine-rich protein kinase (Ste-20-related kinase) (EC 2.7.11.1) (DCHT) (Serine/threonine-protein kinase 39)	STK39 SPAK	Homo sapiens (Human)	545	cellular hypotonic response [GO:0071476]; intracellular signal transduction [GO:0035556]; negative regulation of pancreatic juice secretion [GO:0090188]; negative regulation of potassium ion transmembrane transport [GO:1901380]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of rubidium ion transmembrane transporter activity [GO:2000687]; negative regulation of rubidium ion transport [GO:2000681]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of potassium ion transport [GO:0043268]; protein phosphorylation [GO:0006468]; regulation of blood pressure [GO:0008217]; regulation of inflammatory response [GO:0050727]; regulation of ion homeostasis [GO:2000021]; response to stress [GO:0006950]; signal transduction by protein phosphorylation [GO:0023014]	GO:0001933; GO:0004674; GO:0004702; GO:0005524; GO:0005634; GO:0005737; GO:0005856; GO:0006468; GO:0006950; GO:0008217; GO:0016323; GO:0016324; GO:0018105; GO:0018107; GO:0023014; GO:0035556; GO:0043268; GO:0050727; GO:0071476; GO:0090188; GO:1901017; GO:1901380; GO:2000021; GO:2000681; GO:2000687	0	0	0	PF12202;PF00069;	6207	m.44512	2973853.4	2146259	662338.5	2138425.286	2096810.6	266722	995222.4286	552121.1667	4904194.364	4361729.6	1.106042722
CHOYP_TALDO.2.2	O08605	m.43333	sp	MKNK1_MOUSE	59.398	133	54	0	40	172	35	167	1.44E-49	168	MKNK1_MOUSE	reviewed	MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (MAPK signal-integrating kinase 1) (Mnk1)	Mknk1 Mnk1	Mus musculus (Mouse)	427	extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of translation [GO:0006417]; response to salt stress [GO:0009651]	GO:0004674; GO:0004683; GO:0005516; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0006417; GO:0006468; GO:0009651; GO:0009931; GO:0018105; GO:0035556; GO:0046777; GO:0097192	0	0	0	PF00069;	6254	m.43331	1214584.357	490739.2308	605883.9	1338553.923	9206026.2	1073947.538	199630.6667	1141202.2	382467.1667	1125379.083	0.305125347
CHOYP_TPR.1.2	Q5EE04	m.29645	sp	TPR_XENLA	41.818	165	71	9	81	239	1739	1884	6.14E-21	99	TPR_XENLA	reviewed	Nucleoprotein TPR (NPC-associated intranuclear protein) (Translocated promoter region and nuclear basket protein) (Fragment)	tpr	Xenopus laevis (African clawed frog)	1997	cell division [GO:0051301]; cellular response to heat [GO:0034605]; MAPK import into nucleus [GO:0000189]; mitotic nuclear division [GO:0007067]; mitotic spindle assembly checkpoint [GO:0007094]; mRNA export from nucleus in response to heat stress [GO:0031990]; negative regulation of RNA export from nucleus [GO:0046832]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of translational initiation [GO:0045947]; positive regulation of heterochromatin assembly [GO:0031453]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein import into nucleus [GO:0042307]; regulation of mitotic sister chromatid separation [GO:0010965]; regulation of mitotic spindle assembly [GO:1901673]; response to epidermal growth factor [GO:0070849]; RNA export from nucleus [GO:0006405]; RNA import into nucleus [GO:0006404]	GO:0000122; GO:0000189; GO:0000776; GO:0003682; GO:0003729; GO:0005487; GO:0005643; GO:0005737; GO:0005868; GO:0006404; GO:0006405; GO:0007067; GO:0007094; GO:0010965; GO:0019898; GO:0031072; GO:0031453; GO:0031965; GO:0031990; GO:0034399; GO:0034605; GO:0042307; GO:0042405; GO:0042803; GO:0044615; GO:0045947; GO:0046827; GO:0046832; GO:0051019; GO:0051301; GO:0070849; GO:0072686; GO:0090267; GO:0090316; GO:1901673	0	0	0	PF07926;	6422	m.29645	571120	7985	1101542	537214	883690	765499	666702	398041	228610	1867341.333	1.26588063
CHOYP_TPR.2.2	F1MA98	m.46877	sp	TPR_RAT	32.401	1824	1071	28	14	1803	5	1700	0	785	TPR_RAT	reviewed	Nucleoprotein TPR (Megator) (NPC-associated intranuclear protein) (Translocated promoter region protein)	Tpr	Rattus norvegicus (Rat)	2360	cell division [GO:0051301]; cellular response to heat [GO:0034605]; cellular response to interferon-alpha [GO:0035457]; MAPK import into nucleus [GO:0000189]; mitotic nuclear division [GO:0007067]; mitotic spindle assembly checkpoint [GO:0007094]; mRNA export from nucleus in response to heat stress [GO:0031990]; negative regulation of RNA export from nucleus [GO:0046832]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of translational initiation [GO:0045947]; nuclear pore organization [GO:0006999]; positive regulation of heterochromatin assembly [GO:0031453]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; regulation of mitotic sister chromatid separation [GO:0010965]; regulation of mitotic spindle assembly [GO:1901673]; response to epidermal growth factor [GO:0070849]; RNA export from nucleus [GO:0006405]; RNA import into nucleus [GO:0006404]	GO:0000122; GO:0000189; GO:0000776; GO:0003682; GO:0003729; GO:0005487; GO:0005635; GO:0005643; GO:0005737; GO:0005868; GO:0006404; GO:0006405; GO:0006611; GO:0006999; GO:0007067; GO:0007094; GO:0010965; GO:0019898; GO:0031072; GO:0031453; GO:0031965; GO:0031990; GO:0034399; GO:0034605; GO:0035457; GO:0042307; GO:0042405; GO:0042803; GO:0044615; GO:0045947; GO:0046827; GO:0046832; GO:0051019; GO:0051301; GO:0070849; GO:0072686; GO:0090267; GO:0090316; GO:1901673	0	0	0	PF07926;	6423	m.46877	145863.5385	155709.3333	1741161.813	112858.2	387180.6923	208318.2	2040074.545	847849.8333	255535.5	426889.5294	1.486041715
CHOYP_TRAP1.1.1	Q5XHZ0	m.60651	sp	TRAP1_RAT	60.777	566	216	4	13	574	143	706	0	720	TRAP1_RAT	reviewed	"Heat shock protein 75 kDa, mitochondrial (HSP 75) (TNFR-associated protein 1) (Tumor necrosis factor type 1 receptor-associated protein) (TRAP-1)"	Trap1 Hsp75	Rattus norvegicus (Rat)	706	negative regulation of cellular respiration [GO:1901856]; negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide [GO:1903751]; protein folding [GO:0006457]; response to stress [GO:0006950]; translational attenuation [GO:0009386]	GO:0005524; GO:0005654; GO:0005743; GO:0005758; GO:0005759; GO:0005811; GO:0006457; GO:0006950; GO:0009386; GO:0019901; GO:0044822; GO:0070062; GO:1901856; GO:1903751	0	0	0	PF00183;	6426	m.60651	580726.1818	659955.9333	270457.4545	147976.0667	1759394.467	2201730.882	3965564.308	237882.6429	877740.7222	1262641.474	2.499790778
CHOYP_TXD12.1.1	Q5E936	m.18602	sp	TXD12_BOVIN	49.419	172	81	2	1	168	3	172	3.05E-49	159	TXD12_BOVIN	reviewed	Thioredoxin domain-containing protein 12 (EC 1.8.4.2)	TXNDC12	Bos taurus (Bovine)	172	cell redox homeostasis [GO:0045454]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]	GO:0005788; GO:0015037; GO:0019153; GO:0045454; GO:1902236	0	0	0	0	6534	m.18602	218817	698598	126286	34363	307466	142440	76101	502443	1253623	70684.5	1.476179873
CHOYP_TXND3.1.4	Q95YJ5	m.3505	sp	TXND3_CIOIN	51.832	573	235	7	2	550	65	620	0	561	TXND3_CIOIN	reviewed	Thioredoxin domain-containing protein 3 homolog (Dynein intermediate chain 3)	CiIC3	Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis)	653	cell differentiation [GO:0030154]; cell redox homeostasis [GO:0045454]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; multicellular organism development [GO:0007275]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; spermatogenesis [GO:0007283]; UTP biosynthetic process [GO:0006228]	GO:0004550; GO:0005622; GO:0006183; GO:0006228; GO:0006241; GO:0007275; GO:0007283; GO:0030154; GO:0045454; GO:1902176	0	0	0	PF00334;PF00085;	6535	m.3505	152669.6	106456.2222	314763.4444	236118.0833	127394.6923	468009.0714	901755.8	359669	5085400.679	459100.9	7.759675276
CHOYP_UBE4B.1.1	Q9ES00	m.11223	sp	UBE4B_MOUSE	52.572	1069	463	10	74	1104	106	1168	0	1126	UBE4B_MOUSE	reviewed	Ubiquitin conjugation factor E4 B (EC 6.3.2.-) (Ubiquitin fusion degradation protein 2)	Ube4b Ufd2 Ufd2a	Mus musculus (Mouse)	1173	cellular protein catabolic process [GO:0044257]; granzyme-mediated apoptotic signaling pathway [GO:0008626]; neuron projection development [GO:0031175]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein folding [GO:0006457]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; response to endoplasmic reticulum stress [GO:0034976]; response to UV [GO:0009411]; ubiquitin-dependent protein catabolic process [GO:0006511]; ventricular trabecula myocardium morphogenesis [GO:0003222]	GO:0000151; GO:0000209; GO:0003222; GO:0005524; GO:0005634; GO:0005737; GO:0006457; GO:0006511; GO:0006513; GO:0008626; GO:0009411; GO:0016567; GO:0016874; GO:0019899; GO:0031175; GO:0034450; GO:0034976; GO:0042787; GO:0043161; GO:0044257; GO:0051082; GO:0051865; GO:0061630	PATHWAY: Protein modification; protein ubiquitination. {ECO:0000269|PubMed:11435423}.	0	0	PF04564;PF10408;	6561	m.11223	2096503.5	1764687	981297.5	352648.3333	7544529.667	186393	618783	1235023.333	1528208.5	13941557.5	1.374444615
CHOYP_UBP37.1.1	Q08420	m.15559	sp	SODE_RAT	27.333	150	102	6	21	169	48	191	1.88E-10	61.6	SODE_RAT	reviewed	Extracellular superoxide dismutase [Cu-Zn] (EC-SOD) (EC 1.15.1.1) (Superoxide dismutase B)	Sod3 Sod-3	Rattus norvegicus (Rat)	244	response to copper ion [GO:0046688]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]; response to superoxide [GO:0000303]	GO:0000303; GO:0001666; GO:0004784; GO:0005507; GO:0005615; GO:0005634; GO:0005737; GO:0005802; GO:0006979; GO:0008270; GO:0031012; GO:0046688; GO:0070062	0	0	cd00305;	PF00080;	6572	m.15559	149280	145904.5	715463.6	294631.5	178660.6667	579099.6667	494118	846515.83	402935	452613.6	1.870211463
CHOYP_UBQL4.1.1	Q8R317	m.37426	sp	UBQL1_MOUSE	51.171	598	216	12	7	573	25	577	0	527	UBQL1_MOUSE	reviewed	Ubiquilin-1 (Protein linking IAP with cytoskeleton 1) (PLIC-1)	Ubqln1 Plic1	Mus musculus (Mouse)	582	aggrephagy [GO:0035973]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; cellular response to hypoxia [GO:0071456]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; macroautophagy [GO:0016236]; negative regulation of autophagosome maturation [GO:1901097]; negative regulation of store-operated calcium channel activity [GO:1901340]; negative regulation of toll-like receptor 3 signaling pathway [GO:0034140]; positive regulation of ER-associated ubiquitin-dependent protein catabolic process [GO:1903071]; positive regulation of protein ubiquitination [GO:0031398]; regulation of autophagosome assembly [GO:2000785]; regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902175]; regulation of protein ubiquitination [GO:0031396]; response to endoplasmic reticulum stress [GO:0034976]	GO:0000045; GO:0000502; GO:0005102; GO:0005654; GO:0005737; GO:0005776; GO:0005783; GO:0005886; GO:0016235; GO:0016236; GO:0019215; GO:0019900; GO:0030433; GO:0031396; GO:0031398; GO:0031410; GO:0031593; GO:0034140; GO:0034976; GO:0035973; GO:0042802; GO:0043234; GO:0048471; GO:0071456; GO:0097352; GO:1901097; GO:1901340; GO:1902175; GO:1903071; GO:2000785	0	0	0	PF00627;PF00240;	6575	m.37426	149614.875	613898.1429	1367740.857	689446.6667	1169927.333	1397881.714	272775.3333	5041098.571	350485.6667	77469.625	1.789119691
CHOYP_contig_012079	P74897	m.13839	sp	YQA3_THEAQ	30.612	147	88	4	4	150	3	135	9.77E-11	59.3	YQA3_THEAQ	reviewed	Universal stress protein in QAH/OAS sulfhydrylase 3'region (USP)	0	Thermus aquaticus	137	response to stress [GO:0006950]	GO:0006950	0	0	0	PF00582;	1377	m.13839	NA	58863	32283	35933	28376	706159.6667	27690	30125	493471.25	54103	6.749471766
CHOYP_contig_012079	P74897	m.13839	sp	YQA3_THEAQ	30.612	147	88	4	4	150	3	135	9.77E-11	59.3	YQA3_THEAQ	reviewed	Universal stress protein in QAH/OAS sulfhydrylase 3'region (USP)	0	Thermus aquaticus	137	response to stress [GO:0006950]	GO:0006950	0	0	0	PF00582;	1378	m.13840	NA	58863	32283	35933	28376	706159.6667	27690	30125	493471.25	54103	6.749471766
CHOYP_contig_012079	P74897	m.13840	sp	YQA3_THEAQ	30.612	147	88	4	4	150	3	135	9.77E-11	59.3	YQA3_THEAQ	reviewed	Universal stress protein in QAH/OAS sulfhydrylase 3'region (USP)	0	Thermus aquaticus	137	response to stress [GO:0006950]	GO:0006950	0	0	0	PF00582;	1377	m.13839	NA	58863	32283	35933	28376	706159.6667	27690	30125	493471.25	54103	6.749471766
CHOYP_contig_012079	P74897	m.13840	sp	YQA3_THEAQ	30.612	147	88	4	4	150	3	135	9.77E-11	59.3	YQA3_THEAQ	reviewed	Universal stress protein in QAH/OAS sulfhydrylase 3'region (USP)	0	Thermus aquaticus	137	response to stress [GO:0006950]	GO:0006950	0	0	0	PF00582;	1378	m.13840	NA	58863	32283	35933	28376	706159.6667	27690	30125	493471.25	54103	6.749471766
CHOYP_contig_050645	Q08420	m.60289	sp	SODE_RAT	26.667	150	103	6	31	179	48	191	1.87E-09	58.9	SODE_RAT	reviewed	Extracellular superoxide dismutase [Cu-Zn] (EC-SOD) (EC 1.15.1.1) (Superoxide dismutase B)	Sod3 Sod-3	Rattus norvegicus (Rat)	244	response to copper ion [GO:0046688]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]; response to superoxide [GO:0000303]	GO:0000303; GO:0001666; GO:0004784; GO:0005507; GO:0005615; GO:0005634; GO:0005737; GO:0005802; GO:0006979; GO:0008270; GO:0031012; GO:0046688; GO:0070062	0	0	cd00305;	PF00080;	1664	m.60289	149280	145904.5	715463.6	294631.5	178660.6667	579099.6667	494118	846515.83	402935	452613.6	1.870211463