Fast Gene Set Enrichment Analysis


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Documentation for package ‘fgsea’ version 1.24.0

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calcGseaStat Calculates GSEA statistics for a given query gene set
calcGseaStatBatchCpp Calculates GSEA statistic valus for all gene sets in 'selectedStats' list.
collapsePathways Collapse list of enriched pathways to independent ones.
collapsePathwaysGeseca Collapse list of enriched pathways to independent ones (GESECA version, highly experimental).
collapsePathwaysORA Collapse list of enriched pathways to independent ones. Version for ORA hypergeometric test.
exampleExpressionMatrix Example of expression values obtained for GSE14308.
examplePathways Example list of mouse Reactome pathways.
exampleRanks Example vector of gene-level statistics obtained for Th1 polarization.
fgsea Wrapper to run methods for preranked gene set enrichment analysis.
fgseaLabel Runs label-permuring gene set enrichment analysis.
fgseaMultilevel Runs preranked gene set enrichment analysis.
fgseaSimple Runs preranked gene set enrichment analysis.
fgseaSimpleImpl Runs preranked gene set enrichment analysis for preprocessed input data.
fora Simple overrepresentation analysis based on hypergeometric test
geseca Runs multilevel Monte-Carlo variant for performing gene sets co-regulation analysis
gesecaSimple Runs simple variant for performing gene sets co-regulation analysis
gmtPathways Returns a list of pathways from a GMT file.
mapIdsList Effeciently converts collection of pathways using AnnotationDbi::mapIds function. Parameters are the sames as for mapIds except for keys, which is assumed to be a list of vectors.
multilevelError Calculates the expected error for the standard deviation of the P-value logarithm.
multilevelImpl Calculates P-values for preprocessed data.
plotCoregulationProfile Plots expression profile of a gene set
plotEnrichment Plots GSEA enrichment plot.
plotGesecaTable Plots table of gene set profiles.
plotGseaTable Plots table of enrichment graphs using ggplot and gridExtra.
reactomePathways Returns a list of Reactome pathways for given Entrez gene IDs
writeGmtPathways Write collection of pathways (list of vectors) to a gmt file