Category	Term	Count	%	PValue	Genes	List Total	Pop Hits	Pop Total	Fold Enrichment	Bonferroni	Benjamini	FDR
GOTERM_MF_DIRECT	GO:0008301~DNA binding, bending	7	5.88235294117647	1.7118387961170607E-9	O42130, Q24537, P63159	102	8	4937	42.35171568627451	4.485016606992076E-7	4.485017645826699E-7	4.074176334758605E-7
INTERPRO	IPR017967:HMG_boxA_CS	6	5.042016806722689	1.6806780477349592E-8	Q24537, P63159	108	6	5376	49.77777777777778	6.806723003127679E-6	6.806746093326584E-6	6.7899393128492355E-6
GOTERM_BP_DIRECT	GO:0017055~negative regulation of RNA polymerase II transcription preinitiation complex assembly	6	5.042016806722689	1.803766426753616E-8	Q24537, P63159	103	6	5048	49.00970873786408	1.4682551043088132E-5	1.4682658713774435E-5	1.3095344258231254E-5
UP_SEQ_FEATURE	DNA_BIND:HMG box 1	6	5.042016806722689	1.9227904454137606E-8	Q24537, P63159	107	6	5183	48.4392523364486	1.1267488661315106E-5	5.633776005062318E-6	5.393427199385598E-6
UP_SEQ_FEATURE	DNA_BIND:HMG box 2	6	5.042016806722689	1.9227904454137606E-8	Q24537, P63159	107	6	5183	48.4392523364486	1.1267488661315106E-5	5.633776005062318E-6	5.393427199385598E-6
GOTERM_CC_DIRECT	GO:0000793~condensed chromosome	7	5.88235294117647	5.747332016933007E-8	O42130, P63159, E9PVX6	109	12	5213	27.898318042813457	1.235668785659616E-5	1.2356763836405966E-5	1.1954450595220654E-5
GOTERM_BP_DIRECT	GO:0043537~negative regulation of blood vessel endothelial cell migration	6	5.042016806722689	1.6300019689778109E-7	A4UTP7, P63159	103	8	5048	36.75728155339806	1.326733691966453E-4	3.00031906300921E-5	2.6759602453865928E-5
GOTERM_BP_DIRECT	GO:0002053~positive regulation of mesenchymal cell proliferation	6	5.042016806722689	3.608771194085387E-7	P63159, O88572	103	9	5048	32.67313915857605	2.937108867139271E-4	3.00031906300921E-5	2.6759602453865928E-5
GOTERM_BP_DIRECT	GO:0014911~positive regulation of smooth muscle cell migration	6	5.042016806722689	7.101991975520108E-7	Q8BSK8, P63159	103	10	5048	29.405825242718446	5.779352831306594E-4	3.00031906300921E-5	2.6759602453865928E-5
GOTERM_BP_DIRECT	GO:0034145~positive regulation of toll-like receptor 4 signaling pathway	5	4.201680672268908	7.740380875085186E-7	P63159	103	5	5048	49.009708737864074	6.298687963980365E-4	3.00031906300921E-5	2.6759602453865928E-5
GOTERM_BP_DIRECT	GO:0002270~plasmacytoid dendritic cell activation	5	4.201680672268908	7.740380875085186E-7	P63159	103	5	5048	49.009708737864074	6.298687963980365E-4	3.00031906300921E-5	2.6759602453865928E-5
GOTERM_BP_DIRECT	GO:0050831~male-specific defense response to bacterium	5	4.201680672268908	7.740380875085186E-7	P63159	103	5	5048	49.009708737864074	6.298687963980365E-4	3.00031906300921E-5	2.6759602453865928E-5
GOTERM_BP_DIRECT	GO:0051106~positive regulation of DNA ligation	5	4.201680672268908	7.740380875085186E-7	P63159	103	5	5048	49.009708737864074	6.298687963980365E-4	3.00031906300921E-5	2.6759602453865928E-5
GOTERM_BP_DIRECT	GO:0071642~positive regulation of macrophage inflammatory protein 1 alpha production	5	4.201680672268908	7.740380875085186E-7	P63159	103	5	5048	49.009708737864074	6.298687963980365E-4	3.00031906300921E-5	2.6759602453865928E-5
GOTERM_BP_DIRECT	GO:0045639~positive regulation of myeloid cell differentiation	5	4.201680672268908	7.740380875085186E-7	P63159	103	5	5048	49.009708737864074	6.298687963980365E-4	3.00031906300921E-5	2.6759602453865928E-5
GOTERM_BP_DIRECT	GO:1905455~positive regulation of myeloid progenitor cell differentiation	5	4.201680672268908	7.740380875085186E-7	P63159	103	5	5048	49.009708737864074	6.298687963980365E-4	3.00031906300921E-5	2.6759602453865928E-5
GOTERM_BP_DIRECT	GO:0050930~induction of positive chemotaxis	5	4.201680672268908	7.740380875085186E-7	P63159	103	5	5048	49.009708737864074	6.298687963980365E-4	3.00031906300921E-5	2.6759602453865928E-5
GOTERM_BP_DIRECT	GO:0045063~T-helper 1 cell differentiation	5	4.201680672268908	7.740380875085186E-7	P63159	103	5	5048	49.009708737864074	6.298687963980365E-4	3.00031906300921E-5	2.6759602453865928E-5
GOTERM_BP_DIRECT	GO:2000426~negative regulation of apoptotic cell clearance	5	4.201680672268908	7.740380875085186E-7	P63159	103	5	5048	49.009708737864074	6.298687963980365E-4	3.00031906300921E-5	2.6759602453865928E-5
GOTERM_BP_DIRECT	GO:0002643~regulation of tolerance induction	5	4.201680672268908	7.740380875085186E-7	P63159	103	5	5048	49.009708737864074	6.298687963980365E-4	3.00031906300921E-5	2.6759602453865928E-5
GOTERM_BP_DIRECT	GO:0001773~myeloid dendritic cell activation	5	4.201680672268908	7.740380875085186E-7	P63159	103	5	5048	49.009708737864074	6.298687963980365E-4	3.00031906300921E-5	2.6759602453865928E-5
GOTERM_BP_DIRECT	GO:2001200~positive regulation of dendritic cell differentiation	5	4.201680672268908	7.740380875085186E-7	P63159	103	5	5048	49.009708737864074	6.298687963980365E-4	3.00031906300921E-5	2.6759602453865928E-5
GOTERM_BP_DIRECT	GO:0032425~positive regulation of mismatch repair	5	4.201680672268908	7.740380875085186E-7	P63159	103	5	5048	49.009708737864074	6.298687963980365E-4	3.00031906300921E-5	2.6759602453865928E-5
GOTERM_BP_DIRECT	GO:0097350~neutrophil clearance	5	4.201680672268908	7.740380875085186E-7	P63159	103	5	5048	49.009708737864074	6.298687963980365E-4	3.00031906300921E-5	2.6759602453865928E-5
GOTERM_BP_DIRECT	GO:0035711~T-helper 1 cell activation	5	4.201680672268908	7.740380875085186E-7	P63159	103	5	5048	49.009708737864074	6.298687963980365E-4	3.00031906300921E-5	2.6759602453865928E-5
GOTERM_BP_DIRECT	GO:0002840~regulation of T cell mediated immune response to tumor cell	5	4.201680672268908	7.740380875085186E-7	P63159	103	5	5048	49.009708737864074	6.298687963980365E-4	3.00031906300921E-5	2.6759602453865928E-5
GOTERM_MF_DIRECT	GO:0051861~glycolipid binding	5	4.201680672268908	8.127219073276981E-7	P63159	102	5	4937	48.40196078431373	2.1291055757732824E-4	2.3659237746650768E-5	2.149197932711024E-5
GOTERM_MF_DIRECT	GO:0019958~C-X-C chemokine binding	5	4.201680672268908	8.127219073276981E-7	P63159	102	5	4937	48.40196078431373	2.1291055757732824E-4	2.3659237746650768E-5	2.149197932711024E-5
GOTERM_MF_DIRECT	GO:0050786~RAGE receptor binding	5	4.201680672268908	8.127219073276981E-7	P63159	102	5	4937	48.40196078431373	2.1291055757732824E-4	2.3659237746650768E-5	2.149197932711024E-5
GOTERM_MF_DIRECT	GO:0000402~crossed form four-way junction DNA binding	5	4.201680672268908	8.127219073276981E-7	P63159	102	5	4937	48.40196078431373	2.1291055757732824E-4	2.3659237746650768E-5	2.149197932711024E-5
GOTERM_MF_DIRECT	GO:0010858~calcium-dependent protein kinase regulator activity	5	4.201680672268908	8.127219073276981E-7	P63159	102	5	4937	48.40196078431373	2.1291055757732824E-4	2.3659237746650768E-5	2.149197932711024E-5
GOTERM_MF_DIRECT	GO:0000405~bubble DNA binding	5	4.201680672268908	8.127219073276981E-7	P63159	102	5	4937	48.40196078431373	2.1291055757732824E-4	2.3659237746650768E-5	2.149197932711024E-5
GOTERM_MF_DIRECT	GO:0000401~open form four-way junction DNA binding	5	4.201680672268908	8.127219073276981E-7	P63159	102	5	4937	48.40196078431373	2.1291055757732824E-4	2.3659237746650768E-5	2.149197932711024E-5
GOTERM_MF_DIRECT	GO:0003681~bent DNA binding	5	4.201680672268908	8.127219073276981E-7	P63159	102	5	4937	48.40196078431373	2.1291055757732824E-4	2.3659237746650768E-5	2.149197932711024E-5
UP_SEQ_FEATURE	MUTAGEN:KKK->AAA: Partial cytoplasmic localization; when associated with 181-A--A-183.	5	4.201680672268908	8.139853090668788E-7	P63159	107	5	5183	48.4392523364486	4.76881840925758E-4	1.9874807963049624E-5	1.902690659943829E-5
UP_SEQ_FEATURE	REGION:LPS binding (Lipid A)	5	4.201680672268908	8.139853090668788E-7	P63159	107	5	5183	48.4392523364486	4.76881840925758E-4	1.9874807963049624E-5	1.902690659943829E-5
UP_SEQ_FEATURE	MUTAGEN:C->A: Disrupts interaction with TLR4:LY96 receptor complex and abolishes TNF release from macrophages.	5	4.201680672268908	8.139853090668788E-7	P63159	107	5	5183	48.4392523364486	4.76881840925758E-4	1.9874807963049624E-5	1.902690659943829E-5
UP_SEQ_FEATURE	MOTIF:Nuclear localization signal (NLS) 1	5	4.201680672268908	8.139853090668788E-7	P63159	107	5	5183	48.4392523364486	4.76881840925758E-4	1.9874807963049624E-5	1.902690659943829E-5
UP_SEQ_FEATURE	MUTAGEN:C->S: No effect on nuclear localization. Decreases interaction with BCN1 and impairs in autophagy induction. Abolishes cytokine-stimulating activity and no effect on chemoattractant activity; when associated with S-45.	5	4.201680672268908	8.139853090668788E-7	P63159	107	5	5183	48.4392523364486	4.76881840925758E-4	1.9874807963049624E-5	1.902690659943829E-5
UP_SEQ_FEATURE	MOTIF:Nuclear localization signal (NLS) 2	5	4.201680672268908	8.139853090668788E-7	P63159	107	5	5183	48.4392523364486	4.76881840925758E-4	1.9874807963049624E-5	1.902690659943829E-5
UP_SEQ_FEATURE	SITE:Cleavage; by thrombin:thrombomodulin	5	4.201680672268908	8.139853090668788E-7	P63159	107	5	5183	48.4392523364486	4.76881840925758E-4	1.9874807963049624E-5	1.902690659943829E-5
UP_SEQ_FEATURE	REGION:Binding to AGER/RAGE	5	4.201680672268908	8.139853090668788E-7	P63159	107	5	5183	48.4392523364486	4.76881840925758E-4	1.9874807963049624E-5	1.902690659943829E-5
UP_SEQ_FEATURE	MUTAGEN:C->S: No effect on nuclear localization. Decreases interaction with BCN1 and impairs autophagy induction. Abolishes cytokine-stimulating activity and no effect on chemoattractant activity; when associated with S-23.	5	4.201680672268908	8.139853090668788E-7	P63159	107	5	5183	48.4392523364486	4.76881840925758E-4	1.9874807963049624E-5	1.902690659943829E-5
UP_SEQ_FEATURE	MUTAGEN:KKK->QQQ: Partial cytoplasmic localization (mimicks acetylation); when associated with 181-Q--Q-183.	5	4.201680672268908	8.139853090668788E-7	P63159	107	5	5183	48.4392523364486	4.76881840925758E-4	1.9874807963049624E-5	1.902690659943829E-5
UP_SEQ_FEATURE	SITE:Cleavage; by CASP1	5	4.201680672268908	8.139853090668788E-7	P63159	107	5	5183	48.4392523364486	4.76881840925758E-4	1.9874807963049624E-5	1.902690659943829E-5
UP_SEQ_FEATURE	REGION:LPS binding (delipidated)	5	4.201680672268908	8.139853090668788E-7	P63159	107	5	5183	48.4392523364486	4.76881840925758E-4	1.9874807963049624E-5	1.902690659943829E-5
UP_SEQ_FEATURE	MUTAGEN:F->A: Disrupts association with chromatin; when associated A-38 and A-122.	5	4.201680672268908	8.139853090668788E-7	P63159	107	5	5183	48.4392523364486	4.76881840925758E-4	1.9874807963049624E-5	1.902690659943829E-5
UP_SEQ_FEATURE	MUTAGEN:C->S: Abolishes cytokine-stimulating activity; no effect on chemoattractant activity; impaired nuclear and enhanced cytoplasmic localization, retained activity in autophagy regulation.	5	4.201680672268908	8.139853090668788E-7	P63159	107	5	5183	48.4392523364486	4.76881840925758E-4	1.9874807963049624E-5	1.902690659943829E-5
UP_SEQ_FEATURE	MUTAGEN:KKK->QQQ: Partial cytoplasmic localization (mimicks acetylation); when associated with 27-Q--Q-29.	5	4.201680672268908	8.139853090668788E-7	P63159	107	5	5183	48.4392523364486	4.76881840925758E-4	1.9874807963049624E-5	1.902690659943829E-5
UP_SEQ_FEATURE	MUTAGEN:F->A: Disrupts association with chromatin; when associated A-103 and A-122.	5	4.201680672268908	8.139853090668788E-7	P63159	107	5	5183	48.4392523364486	4.76881840925758E-4	1.9874807963049624E-5	1.902690659943829E-5
UP_SEQ_FEATURE	CROSSLNK:Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-?)	5	4.201680672268908	8.139853090668788E-7	P63159	107	5	5183	48.4392523364486	4.76881840925758E-4	1.9874807963049624E-5	1.902690659943829E-5
UP_SEQ_FEATURE	MUTAGEN:I->A: Disrupts association with chromatin; when associated A-38 and A-103.	5	4.201680672268908	8.139853090668788E-7	P63159	107	5	5183	48.4392523364486	4.76881840925758E-4	1.9874807963049624E-5	1.902690659943829E-5
UP_SEQ_FEATURE	REGION:Cytokine-stimulating activity	5	4.201680672268908	8.139853090668788E-7	P63159	107	5	5183	48.4392523364486	4.76881840925758E-4	1.9874807963049624E-5	1.902690659943829E-5
UP_SEQ_FEATURE	DISULFID:In disulfide HMGB1; alternate	5	4.201680672268908	8.139853090668788E-7	P63159	107	5	5183	48.4392523364486	4.76881840925758E-4	1.9874807963049624E-5	1.902690659943829E-5
UP_SEQ_FEATURE	MUTAGEN:KKK->AAA: Partial cytoplasmic localization; when associated with 27-A--A-29.	5	4.201680672268908	8.139853090668788E-7	P63159	107	5	5183	48.4392523364486	4.76881840925758E-4	1.9874807963049624E-5	1.902690659943829E-5
UP_SEQ_FEATURE	REGION:Sufficient for interaction with HAVCR2	5	4.201680672268908	8.139853090668788E-7	P63159	107	5	5183	48.4392523364486	4.76881840925758E-4	1.9874807963049624E-5	1.902690659943829E-5
GOTERM_CC_DIRECT	GO:0035868~alphav-beta3 integrin-HMGB1 complex	5	4.201680672268908	8.578849968335097E-7	P63159	109	5	5213	47.8256880733945	1.844283444341066E-4	9.22226371596023E-5	8.922003967068501E-5
GOTERM_BP_DIRECT	GO:0033151~V(D)J recombination	5	4.201680672268908	2.2860389340348188E-6	P63159	103	6	5048	40.84142394822006	0.001859107534015414	6.002695781626911E-5	5.3537556971267046E-5
GOTERM_BP_DIRECT	GO:2000343~positive regulation of chemokine (C-X-C motif) ligand 2 production	5	4.201680672268908	2.2860389340348188E-6	P63159	103	6	5048	40.84142394822006	0.001859107534015414	6.002695781626911E-5	5.3537556971267046E-5
GOTERM_BP_DIRECT	GO:0032392~DNA geometric change	5	4.201680672268908	2.2860389340348188E-6	P63159	103	6	5048	40.84142394822006	0.001859107534015414	6.002695781626911E-5	5.3537556971267046E-5
GOTERM_BP_DIRECT	GO:0032103~positive regulation of response to external stimulus	5	4.201680672268908	2.2860389340348188E-6	P63159	103	6	5048	40.84142394822006	0.001859107534015414	6.002695781626911E-5	5.3537556971267046E-5
GOTERM_BP_DIRECT	GO:0051450~myoblast proliferation	5	4.201680672268908	2.2860389340348188E-6	P63159	103	6	5048	40.84142394822006	0.001859107534015414	6.002695781626911E-5	5.3537556971267046E-5
GOTERM_BP_DIRECT	GO:0002437~inflammatory response to antigenic stimulus	5	4.201680672268908	2.2860389340348188E-6	P63159	103	6	5048	40.84142394822006	0.001859107534015414	6.002695781626911E-5	5.3537556971267046E-5
GOTERM_BP_DIRECT	GO:0034137~positive regulation of toll-like receptor 2 signaling pathway	5	4.201680672268908	2.2860389340348188E-6	P63159	103	6	5048	40.84142394822006	0.001859107534015414	6.002695781626911E-5	5.3537556971267046E-5
GOTERM_BP_DIRECT	GO:0033034~positive regulation of myeloid cell apoptotic process	5	4.201680672268908	2.2860389340348188E-6	P63159	103	6	5048	40.84142394822006	0.001859107534015414	6.002695781626911E-5	5.3537556971267046E-5
GOTERM_BP_DIRECT	GO:0032732~positive regulation of interleukin-1 production	5	4.201680672268908	2.2860389340348188E-6	P63159	103	6	5048	40.84142394822006	0.001859107534015414	6.002695781626911E-5	5.3537556971267046E-5
GOTERM_BP_DIRECT	GO:0043371~negative regulation of CD4-positive, alpha-beta T cell differentiation	5	4.201680672268908	2.2860389340348188E-6	P63159	103	6	5048	40.84142394822006	0.001859107534015414	6.002695781626911E-5	5.3537556971267046E-5
GOTERM_MF_DIRECT	GO:0140297~DNA-binding transcription factor binding	10	8.403361344537815	3.1475067866773458E-6	Q91WA3, P49454, Q24537, Q9UKV0, A2VDZ3, P63159	102	61	4937	7.934747669559627	8.243081471179803E-4	8.246467781094645E-5	7.491066152292083E-5
GOTERM_BP_DIRECT	GO:0090303~positive regulation of wound healing	6	5.042016806722689	3.455760387831755E-6	Q8CIY2, P63159	103	13	5048	22.61986557132188	0.002809041056355044	8.790590486547026E-5	7.840256379893294E-5
GOTERM_MF_DIRECT	GO:0042277~peptide binding	7	5.88235294117647	3.6143641484482105E-6	Q68FD5, Q8BSK8, P63159	102	22	4937	15.400623885918003	9.465168882547559E-4	8.608758244485738E-5	7.820169703006128E-5
GOTERM_BP_DIRECT	GO:0005980~glycogen catabolic process	5	4.201680672268908	5.251263918292579E-6	P63159	103	7	5048	35.00693481276005	0.004265417209792455	1.187369119302822E-4	1.0590048901890035E-4
GOTERM_BP_DIRECT	GO:0002281~macrophage activation involved in immune response	5	4.201680672268908	5.251263918292579E-6	P63159	103	7	5048	35.00693481276005	0.004265417209792455	1.187369119302822E-4	1.0590048901890035E-4
GOTERM_BP_DIRECT	GO:0045819~positive regulation of glycogen catabolic process	5	4.201680672268908	5.251263918292579E-6	P63159	103	7	5048	35.00693481276005	0.004265417209792455	1.187369119302822E-4	1.0590048901890035E-4
GOTERM_BP_DIRECT	GO:0035767~endothelial cell chemotaxis	5	4.201680672268908	5.251263918292579E-6	P63159	103	7	5048	35.00693481276005	0.004265417209792455	1.187369119302822E-4	1.0590048901890035E-4
GOTERM_CC_DIRECT	GO:0005793~endoplasmic reticulum-Golgi intermediate compartment	8	6.722689075630252	8.314854760451655E-6	O57590, P55937, P63159, Q6P5E4	109	37	5213	10.340689313166378	0.0017861042197402366	4.7598869626851924E-4	4.604913898783814E-4
GOTERM_CC_DIRECT	GO:0017053~transcription repressor complex	6	5.042016806722689	8.855603651507335E-6	Q86NP2, P63159	109	15	5213	19.1302752293578	0.0019021518272799298	4.7598869626851924E-4	4.604913898783814E-4
GOTERM_BP_DIRECT	GO:0002318~myeloid progenitor cell differentiation	5	4.201680672268908	1.0339527639805144E-5	P63159	103	8	5048	30.631067961165048	0.008381100111008233	1.9572966276282298E-4	1.7456969922089618E-4
GOTERM_BP_DIRECT	GO:0032735~positive regulation of interleukin-12 production	5	4.201680672268908	1.0339527639805144E-5	P63159	103	8	5048	30.631067961165048	0.008381100111008233	1.9572966276282298E-4	1.7456969922089618E-4
GOTERM_BP_DIRECT	GO:0032689~negative regulation of type II interferon production	5	4.201680672268908	1.0339527639805144E-5	P63159	103	8	5048	30.631067961165048	0.008381100111008233	1.9572966276282298E-4	1.7456969922089618E-4
GOTERM_BP_DIRECT	GO:0071639~positive regulation of monocyte chemotactic protein-1 production	5	4.201680672268908	1.0339527639805144E-5	P63159	103	8	5048	30.631067961165048	0.008381100111008233	1.9572966276282298E-4	1.7456969922089618E-4
GOTERM_BP_DIRECT	GO:0008156~negative regulation of DNA replication	5	4.201680672268908	1.0339527639805144E-5	P63159	103	8	5048	30.631067961165048	0.008381100111008233	1.9572966276282298E-4	1.7456969922089618E-4
GOTERM_BP_DIRECT	GO:0034341~response to type II interferon	5	4.201680672268908	1.0339527639805144E-5	P63159	103	8	5048	30.631067961165048	0.008381100111008233	1.9572966276282298E-4	1.7456969922089618E-4
GOTERM_BP_DIRECT	GO:0034165~positive regulation of toll-like receptor 9 signaling pathway	5	4.201680672268908	1.0339527639805144E-5	P63159	103	8	5048	30.631067961165048	0.008381100111008233	1.9572966276282298E-4	1.7456969922089618E-4
GOTERM_MF_DIRECT	GO:0048018~receptor ligand activity	5	4.201680672268908	1.0850068989906355E-5	P63159	102	8	4937	30.251225490196077	0.002838696756480963	2.0305129109681895E-4	1.8445117282840805E-4
GOTERM_MF_DIRECT	GO:0097100~supercoiled DNA binding	5	4.201680672268908	1.0850068989906355E-5	P63159	102	8	4937	30.251225490196077	0.002838696756480963	2.0305129109681895E-4	1.8445117282840805E-4
GOTERM_MF_DIRECT	GO:0000400~four-way junction DNA binding	5	4.201680672268908	1.0850068989906355E-5	P63159	102	8	4937	30.251225490196077	0.002838696756480963	2.0305129109681895E-4	1.8445117282840805E-4
GOTERM_BP_DIRECT	GO:0045931~positive regulation of mitotic cell cycle	6	5.042016806722689	1.117513636729012E-5	Q8BSK8, P63159	103	16	5048	18.37864077669903	0.00905536282774444	2.067400227948672E-4	1.8438975006028696E-4
GOTERM_CC_DIRECT	GO:0045121~membrane raft	9	7.563025210084033	1.2338916855025013E-5	O46522, P36573, P63159, O88572, P43006	109	54	5213	7.970948012232417	0.0026493677049904685	5.305734247660756E-4	5.132989411690405E-4
GOTERM_BP_DIRECT	GO:0070374~positive regulation of ERK1 and ERK2 cascade	7	5.88235294117647	1.542613974457424E-5	P63159, Q9H4G4, Q3UVU3	103	28	5048	12.252427184466018	0.012478464758513552	2.7904172782407624E-4	2.4887505454579775E-4
GOTERM_CC_DIRECT	GO:0009986~cell surface	12	10.084033613445378	1.6506780971529394E-5	P28491, Q8BSK8, Q8N2E2, Q8CIY2, P63159, O75096, O88572, P43006	109	112	5213	5.1241808650065535	0.00354269698855858	5.914929848131366E-4	5.722350736796857E-4
UP_KW_BIOLOGICAL_PROCESS	KW-1064~Adaptive immunity	7	5.88235294117647	1.8122830139376362E-5	O62703, Q5RBP9, P63159	76	25	3159	11.638421052631578	0.001213503730248977	0.0012142296193382162	0.0011417382987807109
GOTERM_BP_DIRECT	GO:0032733~positive regulation of interleukin-10 production	5	4.201680672268908	1.832244805590255E-5	P63159	103	9	5048	27.22761596548004	0.014803937460413086	3.0437699423478925E-4	2.714713732364337E-4
GOTERM_BP_DIRECT	GO:0032757~positive regulation of interleukin-8 production	5	4.201680672268908	1.832244805590255E-5	P63159	103	9	5048	27.22761596548004	0.014803937460413086	3.0437699423478925E-4	2.714713732364337E-4
GOTERM_BP_DIRECT	GO:1905564~positive regulation of vascular endothelial cell proliferation	5	4.201680672268908	1.832244805590255E-5	P63159	103	9	5048	27.22761596548004	0.014803937460413086	3.0437699423478925E-4	2.714713732364337E-4
GOTERM_BP_DIRECT	GO:0090026~positive regulation of monocyte chemotaxis	5	4.201680672268908	1.832244805590255E-5	P63159	103	9	5048	27.22761596548004	0.014803937460413086	3.0437699423478925E-4	2.714713732364337E-4
GOTERM_MF_DIRECT	GO:0008097~5S rRNA binding	5	4.201680672268908	1.922351654852873E-5	P63159	102	9	4937	26.889978213507625	0.005023947295191955	3.3577075571430184E-4	3.050131292366559E-4
UP_SEQ_FEATURE	MOTIF:Cell attachment site	6	5.042016806722689	2.25646297942617E-5	P82198, P15989, P37889, A6NMZ7, P22105, A2AX52	107	18	5183	16.146417445482864	0.013135982154340864	5.289149223774943E-4	5.063502925832326E-4
GOTERM_BP_DIRECT	GO:0007204~positive regulation of cytosolic calcium ion concentration	6	5.042016806722689	2.834656285323103E-5	P63159, O88572	103	19	5048	15.47675012774655	0.022810250389118436	4.614820432506012E-4	4.1159209262891453E-4
GOTERM_MF_DIRECT	GO:0061629~RNA polymerase II-specific DNA-binding transcription factor binding	8	6.722689075630252	2.919361300852083E-5	A4UTP7, Q9UKV0, A2VDZ3, P63159	102	45	4937	8.60479302832244	0.007619660333856748	4.780454130145286E-4	4.3425499350174736E-4
GOTERM_BP_DIRECT	GO:0098761~cellular response to interleukin-7	5	4.201680672268908	3.0063947294662685E-5	P63159	103	10	5048	24.504854368932037	0.02417539915527267	4.7061640572798895E-4	4.1973895646009825E-4
GOTERM_BP_DIRECT	GO:0042104~positive regulation of activated T cell proliferation	5	4.201680672268908	3.0063947294662685E-5	P63159	103	10	5048	24.504854368932037	0.02417539915527267	4.7061640572798895E-4	4.1973895646009825E-4
GOTERM_MF_DIRECT	GO:0001530~lipopolysaccharide binding	5	4.201680672268908	3.1536460488101376E-5	P63159	102	10	4937	24.200980392156865	0.008228640796139164	4.860325086989742E-4	4.4151044683341927E-4
UP_KW_PTM	KW-0558~Oxidation	5	4.201680672268908	3.337425945125891E-5	P63159	83	9	3470	23.22623828647925	6.005662827500702E-4	6.341109295739193E-4	5.673624106714015E-4
UP_KW_DOMAIN	KW-0732~Signal	30	25.210084033613445	4.4087169720870224E-5	A4IGY6, P20481, A4QP81, Q28J24, Q9VDG5, P15989, Q8N2E2, Q8CIY2, P19477, P54315, Q8HZK2, Q5RBP9, Q99805, Q9I9M5, O88572, Q9XS79, Q9VAF5, Q9GMB0, Q641F3, P28491, P37889, O75096, A2AX52, Q6P5E4, P43307, A0A0K0YB03, P82198, A6NMZ7, P29617, P22105	76	670	3542	2.086802827965436	6.611034985506414E-4	6.613075458130534E-4	6.613075458130534E-4
GOTERM_BP_DIRECT	GO:0030099~myeloid cell differentiation	5	4.201680672268908	4.651123540252856E-5	P63159	103	11	5048	22.27714033539276	0.03715325784542889	6.883662839574227E-4	6.13948307313377E-4
GOTERM_BP_DIRECT	GO:0043277~apoptotic cell clearance	5	4.201680672268908	4.651123540252856E-5	P63159	103	11	5048	22.27714033539276	0.03715325784542889	6.883662839574227E-4	6.13948307313377E-4
GOTERM_BP_DIRECT	GO:1903672~positive regulation of sprouting angiogenesis	5	4.201680672268908	4.651123540252856E-5	P63159	103	11	5048	22.27714033539276	0.03715325784542889	6.883662839574227E-4	6.13948307313377E-4
GOTERM_MF_DIRECT	GO:0070182~DNA polymerase binding	5	4.201680672268908	4.8780079969077825E-5	P63159	102	11	4937	22.000891265597147	0.012699366460557249	7.10021163994355E-4	6.449810573689179E-4
UP_SEQ_FEATURE	DOMAIN:HMG box	6	5.042016806722689	5.1031253981261105E-5	Q24537, P63159	107	21	5183	13.839786381842456	0.029462345338172047	0.0011501659551161158	0.0011010974416725953
UP_KW_BIOLOGICAL_PROCESS	KW-0145~Chemotaxis	5	4.201680672268908	5.52732832322842E-5	P63159	76	10	3159	20.782894736842106	0.003696563153666066	0.0018516549882815207	0.0017411084218169524
GOTERM_BP_DIRECT	GO:0032868~response to insulin	6	5.042016806722689	6.1172724306584E-5	Q8BSK8, P63159	103	22	5048	13.366284201235658	0.04857661972307348	8.585275445786101E-4	7.657137559755171E-4
GOTERM_BP_DIRECT	GO:0009749~response to glucose	6	5.042016806722689	6.1172724306584E-5	Q8BSK8, P63159	103	22	5048	13.366284201235658	0.04857661972307348	8.585275445786101E-4	7.657137559755171E-4
GOTERM_BP_DIRECT	GO:0045663~positive regulation of myoblast differentiation	6	5.042016806722689	6.1172724306584E-5	A4UTP7, P63159	103	22	5048	13.366284201235658	0.04857661972307348	8.585275445786101E-4	7.657137559755171E-4
GOTERM_BP_DIRECT	GO:0009410~response to xenobiotic stimulus	8	6.722689075630252	6.243107501706209E-5	P49454, Q8BSK8, P63159, P43006	103	51	5048	7.687797449076717	0.049550721523421104	8.613372044726872E-4	7.682196688540182E-4
UP_SEQ_FEATURE	DNA_BIND:HMG box	6	5.042016806722689	6.497250539022365E-5	Q24537, P63159	107	22	5183	13.2107051826678	0.0373593802886909	0.0014101440058767057	0.0013499842786635359
GOTERM_BP_DIRECT	GO:0032731~positive regulation of interleukin-1 beta production	5	4.201680672268908	6.868625812467955E-5	P63159	103	12	5048	20.42071197411003	0.05437815829464032	9.318435685581525E-4	8.311037233086226E-4
SMART	SM00398:HMG	6	5.042016806722689	7.080974918577671E-5	Q24537, P63159	62	23	3035	12.769985974754558	0.005226401556479687	0.005239921439747476	0.005239921439747476
INTERPRO	IPR009071:HMG_box_dom	6	5.042016806722689	7.192185429055754E-5	Q24537, P63159	108	23	5376	12.985507246376809	0.02870922725428493	0.012071577046558948	0.012041770683481024
INTERPRO	IPR036910:HMG_box_dom_sf	6	5.042016806722689	8.941908923376998E-5	Q24537, P63159	108	24	5376	12.444444444444445	0.0355683842366985	0.012071577046558948	0.012041770683481024
GOTERM_BP_DIRECT	GO:0051384~response to glucocorticoid	5	4.201680672268908	9.767759045189021E-5	P63159	103	13	5048	18.849887976101567	0.07643439471303093	0.0013034353873416168	0.0011625234535749555
UP_KW_CELLULAR_COMPONENT	KW-0964~Secreted	16	13.445378151260504	1.3386304037924044E-4	P20481, Q641F3, P82198, P28491, P15989, P37889, A6NMZ7, Q8N2E2, P63159, P22105, P54315, A2AX52	102	238	4724	3.113527764046795	0.004141432543153356	0.002523753729350749	0.002523753729350749
GOTERM_BP_DIRECT	GO:0045089~positive regulation of innate immune response	5	4.201680672268908	1.3463275827800815E-4	P63159	103	14	5048	17.503467406380025	0.10380606415628901	0.0017123603943484161	0.001527240351716155
GOTERM_BP_DIRECT	GO:2000819~regulation of nucleotide-excision repair	5	4.201680672268908	1.3463275827800815E-4	P63159	103	14	5048	17.503467406380025	0.10380606415628901	0.0017123603943484161	0.001527240351716155
GOTERM_BP_DIRECT	GO:0032727~positive regulation of interferon-alpha production	5	4.201680672268908	1.3463275827800815E-4	P63159	103	14	5048	17.503467406380025	0.10380606415628901	0.0017123603943484161	0.001527240351716155
GOTERM_MF_DIRECT	GO:0001786~phosphatidylserine binding	6	5.042016806722689	1.516810016540254E-4	Q5NVM9, P63159	102	26	4937	11.169683257918551	0.03896402588682424	0.0020916011807028765	0.0019000041259820022
KEGG_PATHWAY	rno03410:Base excision repair	4	3.361344537815126	1.5602189253825508E-4	P63159	63	5	2412	30.628571428571426	0.034649179104032424	0.03526094771364565	0.03510492582110739
UP_KW_CELLULAR_COMPONENT	KW-0272~Extracellular matrix	8	6.722689075630252	1.6282282124843543E-4	Q641F3, P82198, P28491, P15989, P37889, A6NMZ7, P22105, A2AX52	102	56	4724	6.616246498599439	0.0050351990988328765	0.002523753729350749	0.002523753729350749
GOTERM_BP_DIRECT	GO:0002218~activation of innate immune response	5	4.201680672268908	1.80750971115656E-4	P63159	103	15	5048	16.336569579288025	0.13683083650466066	0.002195989410270806	0.001958585149700989
GOTERM_BP_DIRECT	GO:0032755~positive regulation of interleukin-6 production	5	4.201680672268908	1.80750971115656E-4	P63159	103	15	5048	16.336569579288025	0.13683083650466066	0.002195989410270806	0.001958585149700989
GOTERM_BP_DIRECT	GO:0001935~endothelial cell proliferation	5	4.201680672268908	1.80750971115656E-4	P63159	103	15	5048	16.336569579288025	0.13683083650466066	0.002195989410270806	0.001958585149700989
GOTERM_BP_DIRECT	GO:0031175~neuron projection development	7	5.88235294117647	2.224732943150839E-4	P15146, P63159, P22105	103	44	5048	7.796999117387466	0.16565926822431332	0.002663136199595269	0.0023752295834228074
GOTERM_BP_DIRECT	GO:0006935~chemotaxis	5	4.201680672268908	2.3727624936385438E-4	P63159	103	16	5048	15.315533980582524	0.17565470104037262	0.002799171985248949	0.002496558797654468
GOTERM_BP_DIRECT	GO:0032496~response to lipopolysaccharide	6	5.042016806722689	2.4653629352485405E-4	Q8BSK8, P63159	103	29	5048	10.139939738868431	0.18184648146243143	0.002866864898989017	0.002556933558557772
UP_KW_MOLECULAR_FUNCTION	KW-0358~Heparin-binding	5	4.201680672268908	2.6069044878267937E-4	P63159	69	16	3261	14.769021739130434	0.011148539929266565	0.011209689297655213	0.011209689297655213
GOTERM_BP_DIRECT	GO:0001654~eye development	5	4.201680672268908	3.0549093027086E-4	P63159	103	17	5048	14.414620217018845	0.2201920504448488	0.0034537446838955564	0.003080366880231172
GOTERM_BP_DIRECT	GO:0043536~positive regulation of blood vessel endothelial cell migration	5	4.201680672268908	3.0549093027086E-4	P63159	103	17	5048	14.414620217018845	0.2201920504448488	0.0034537446838955564	0.003080366880231172
GOTERM_BP_DIRECT	GO:0071222~cellular response to lipopolysaccharide	6	5.042016806722689	3.41606116085278E-4	A4UTP7, P63159	103	31	5048	9.485750078296274	0.24279017483019683	0.0038091421711426887	0.003397343017505641
GOTERM_MF_DIRECT	GO:0003725~double-stranded RNA binding	6	5.042016806722689	3.612522708585531E-4	Q68FD5, P63159	102	31	4937	9.368121442125236	0.09032255195566441	0.004732404748247045	0.004298902023216782
GOTERM_BP_DIRECT	GO:0031507~heterochromatin formation	5	4.201680672268908	3.86709537124126E-4	P63159	103	18	5048	13.61380798274002	0.27009613364131213	0.004253804908365386	0.00379393410746102
GOTERM_MF_DIRECT	GO:0030295~protein kinase activator activity	5	4.201680672268908	4.0503774024104616E-4	P63159	102	18	4937	13.444989106753813	0.10070250811383885	0.004823631270143368	0.004381771917153136
GOTERM_MF_DIRECT	GO:0005125~cytokine activity	5	4.201680672268908	4.0503774024104616E-4	P63159	102	18	4937	13.444989106753813	0.10070250811383885	0.004823631270143368	0.004381771917153136
GOTERM_BP_DIRECT	GO:0071347~cellular response to interleukin-1	5	4.201680672268908	4.822729969314975E-4	P63159	103	19	5048	12.897291773122125	0.32474502112541814	0.00516539762502946	0.00460697626016141
GOTERM_BP_DIRECT	GO:0006284~base-excision repair	5	4.201680672268908	4.822729969314975E-4	P63159	103	19	5048	12.897291773122125	0.32474502112541814	0.00516539762502946	0.00460697626016141
KEGG_PATHWAY	rno04217:Necroptosis	4	3.361344537815126	5.262449669508203E-4	P63159	63	7	2412	21.877551020408163	0.11215905411683125	0.0594656812654427	0.05920255878196729
GOTERM_BP_DIRECT	GO:0006954~inflammatory response	7	5.88235294117647	5.631038872928875E-4	O46522, Q9UKV0, P63159	103	52	5048	6.597460791635548	0.3677659788350941	0.005952812522810525	0.005309265223047225
GOTERM_MF_DIRECT	GO:0003697~single-stranded DNA binding	6	5.042016806722689	5.635266575971124E-4	Q24537, P63159	102	34	4937	8.54152249134948	0.13729769459219077	0.006151832678768477	0.005588306021171364
GOTERM_MF_DIRECT	GO:0005178~integrin binding	6	5.042016806722689	5.635266575971124E-4	P63159, P22105	102	34	4937	8.54152249134948	0.13729769459219077	0.006151832678768477	0.005588306021171364
GOTERM_MF_DIRECT	GO:0008201~heparin binding	6	5.042016806722689	6.468842635925173E-4	P63159, P22105	102	35	4937	8.297478991596638	0.15594575816580647	0.006779347082449582	0.006158338189400764
GOTERM_CC_DIRECT	GO:0062023~collagen-containing extracellular matrix	8	6.722689075630252	7.131881283893636E-4	Q641F3, P82198, P15989, P37889, A6NMZ7, P19477, P22105, A2AX52	109	73	5213	5.241171295714466	0.14220501402029206	0.021905063943387596	0.021191875814998234
GOTERM_BP_DIRECT	GO:1901224~positive regulation of non-canonical NF-kappaB signal transduction	5	4.201680672268908	7.218978325559773E-4	P63159	103	21	5048	11.66897827092002	0.4444724301167199	0.0074382890595008294	0.006634149701716955
GOTERM_BP_DIRECT	GO:0032760~positive regulation of tumor necrosis factor production	5	4.201680672268908	7.218978325559773E-4	P63159	103	21	5048	11.66897827092002	0.4444724301167199	0.0074382890595008294	0.006634149701716955
GOTERM_MF_DIRECT	GO:0016829~lyase activity	6	5.042016806722689	7.391545871336578E-4	Q8R5I6, P63159	102	36	4937	8.066993464052288	0.17611976779443306	0.007448403916500705	0.006766107374531175
GOTERM_BP_DIRECT	GO:0007623~circadian rhythm	5	4.201680672268908	8.687256343954142E-4	P63159	103	22	5048	11.13857016769638	0.5071005104536839	0.00883928332997334	0.007883685132138383
UP_KW_PTM	KW-0379~Hydroxylation	6	5.042016806722689	9.199328638086333E-4	Q9XS79, Q6P823, P28491, P15989, A6NMZ7, A2AX52	83	33	3470	7.601314348302299	0.01642994433247058	0.008739362206182016	0.007819429342373382
GOTERM_BP_DIRECT	GO:0032728~positive regulation of interferon-beta production	5	4.201680672268908	0.0010354217929374769	P63159	103	23	5048	10.654284508231322	0.5696988578753195	0.010405349869766743	0.009280447181143313
KEGG_PATHWAY	rno04613:Neutrophil extracellular trap formation	4	3.361344537815126	0.001217205953434582	P63159	63	9	2412	17.015873015873016	0.24062237917285045	0.09169618182540518	0.09129044650759364
GOTERM_BP_DIRECT	GO:0030324~lung development	5	4.201680672268908	0.0012233837370282372	P63159	103	24	5048	10.210355987055015	0.6308100519373497	0.012144321487085186	0.010831421866859758
GOTERM_BP_DIRECT	GO:0010976~positive regulation of neuron projection development	6	5.042016806722689	0.0012839296948717826	P63159, O88572	103	41	5048	7.172152498224012	0.6485860044246178	0.01259179242922447	0.011230517572011014
UP_KW_BIOLOGICAL_PROCESS	KW-0072~Autophagy	8	6.722689075630252	0.001372135165617625	Q5NVM9, Q68FD5, P23787, P63159	76	72	3159	4.618421052631579	0.08789137180802653	0.03064435203212696	0.028814838477970128
UP_KW_PTM	KW-0013~ADP-ribosylation	6	5.042016806722689	0.00138231380806308	Q6P823, P63159	83	36	3470	6.967871485943775	0.02459144163357807	0.00875465411773284	0.00783311157902412
GOTERM_BP_DIRECT	GO:0051402~neuron apoptotic process	5	4.201680672268908	0.0014340071530066652	P63159	103	25	5048	9.801941747572815	0.689048885970474	0.013732727324087358	0.012248108153915752
GOTERM_BP_DIRECT	GO:0000902~cell morphogenesis	5	4.201680672268908	0.0014340071530066652	P63159	103	25	5048	9.801941747572815	0.689048885970474	0.013732727324087358	0.012248108153915752
GOTERM_BP_DIRECT	GO:0043410~positive regulation of MAPK cascade	5	4.201680672268908	0.0019287903711212161	P63159	103	27	5048	9.075871988493349	0.7922773383455461	0.018256225140612443	0.016282579179465153
GOTERM_MF_DIRECT	GO:0003684~damaged DNA binding	5	4.201680672268908	0.0020168031420770526	P63159	102	27	4937	8.963326071169208	0.41076841106559037	0.01957046011941436	0.01777774621534587
GOTERM_MF_DIRECT	GO:0003727~single-stranded RNA binding	5	4.201680672268908	0.0023163737677483393	P63159	102	28	4937	8.643207282913165	0.45534020382583107	0.02167464025535946	0.019689177025860885
UP_SEQ_FEATURE	DOMAIN:VWFA 5	3	2.5210084033613445	0.0024203312269341563	P15989, A6NMZ7, A2AX52	107	4	5183	36.32943925233645	0.7582940244243342	0.04297921512070956	0.04114563085788066
UP_SEQ_FEATURE	DOMAIN:VWFA 3	3	2.5210084033613445	0.0024203312269341563	P15989, A6NMZ7, A2AX52	107	4	5183	36.32943925233645	0.7582940244243342	0.04297921512070956	0.04114563085788066
UP_SEQ_FEATURE	DOMAIN:VWFA 6	3	2.5210084033613445	0.0024203312269341563	P15989, A6NMZ7, A2AX52	107	4	5183	36.32943925233645	0.7582940244243342	0.04297921512070956	0.04114563085788066
UP_SEQ_FEATURE	DOMAIN:VWFA 8	3	2.5210084033613445	0.0024203312269341563	P15989, A6NMZ7, A2AX52	107	4	5183	36.32943925233645	0.7582940244243342	0.04297921512070956	0.04114563085788066
UP_SEQ_FEATURE	DOMAIN:VWFA 7	3	2.5210084033613445	0.0024203312269341563	P15989, A6NMZ7, A2AX52	107	4	5183	36.32943925233645	0.7582940244243342	0.04297921512070956	0.04114563085788066
UP_SEQ_FEATURE	DOMAIN:VWFA 4	3	2.5210084033613445	0.0024203312269341563	P15989, A6NMZ7, A2AX52	107	4	5183	36.32943925233645	0.7582940244243342	0.04297921512070956	0.04114563085788066
GOTERM_BP_DIRECT	GO:0010508~positive regulation of autophagy	5	4.201680672268908	0.0025307668808378595	P63159	103	29	5048	8.449949782390359	0.8728840215716047	0.0236786694368048	0.021118813281474552
INTERPRO	IPR008160:Collagen	4	3.361344537815126	0.0029302318234027355	Q641F3, P15989, A6NMZ7, A2AX52	108	15	5376	13.274074074074074	0.6953177991056096	0.21834963472837293	0.21781049982780906
GOTERM_BP_DIRECT	GO:0006310~DNA recombination	5	4.201680672268908	0.0032506910041009574	P63159	103	31	5048	7.904791731913561	0.9293751057013669	0.030068891787933857	0.026818200783832898
GOTERM_BP_DIRECT	GO:0043065~positive regulation of apoptotic process	7	5.88235294117647	0.003583346628899911	O42130, P63159, O88572	103	74	5048	4.6360535292574125	0.9461785238145919	0.03277352984184863	0.029230445534621747
INTERPRO	IPR013112:FAD-bd_8	3	2.5210084033613445	0.003773944303947187	O46522, Q8CIY2, Q8HZK2	108	5	5376	29.866666666666667	0.7837540491728323	0.21834963472837293	0.21781049982780906
INTERPRO	IPR013130:Fe3_Rdtase_TM_dom	3	2.5210084033613445	0.003773944303947187	O46522, Q8CIY2, Q8HZK2	108	5	5376	29.866666666666667	0.7837540491728323	0.21834963472837293	0.21781049982780906
INTERPRO	IPR013121:Fe_red_NAD-bd_6	3	2.5210084033613445	0.003773944303947187	O46522, Q8CIY2, Q8HZK2	108	5	5376	29.866666666666667	0.7837540491728323	0.21834963472837293	0.21781049982780906
GOTERM_BP_DIRECT	GO:0006914~autophagy	7	5.88235294117647	0.0038323303303170334	Q68FD5, P23787, P63159	103	75	5048	4.574239482200647	0.956085455956126	0.034661298765311835	0.03091413133122407
UP_KW_BIOLOGICAL_PROCESS	KW-0395~Inflammatory response	5	4.201680672268908	0.00389587915292373	P63159	76	28	3159	7.422462406015038	0.2301300592394423	0.06525597581147248	0.06136009665854875
UP_SEQ_FEATURE	DOMAIN:Ferric oxidoreductase	3	2.5210084033613445	0.003980070826954037	O46522, Q8CIY2, Q8HZK2	107	5	5183	29.06355140186916	0.9033805545407226	0.06859769131161958	0.06567116864474161
GOTERM_MF_DIRECT	GO:0016175~superoxide-generating NAD(P)H oxidase activity	3	2.5210084033613445	0.003980780572968886	O46522, Q8CIY2, Q8HZK2	102	5	4937	29.041176470588237	0.6483243377468749	0.03596429345233959	0.03266985435746879
GOTERM_CC_DIRECT	GO:0005783~endoplasmic reticulum	19	15.966386554621847	0.004053847684819723	Q9Z0R9, O57590, P28491, Q8TCJ2, Q8CIY2, Q8HZK2, Q6P5E4, Q1HG43, P43307, Q8BHL8, P23787, A6QL88, P63159, Q28XE2, O88572	109	444	5213	2.0465947598975123	0.5824490315071891	0.09753269674118316	0.09435721359147022
GOTERM_CC_DIRECT	GO:0043020~NADPH oxidase complex	3	2.5210084033613445	0.004082764049630923	O46522, Q8CIY2, Q8HZK2	109	5	5213	28.6954128440367	0.5850474391152047	0.09753269674118316	0.09435721359147022
GOTERM_BP_DIRECT	GO:0008284~positive regulation of cell population proliferation	7	5.88235294117647	0.004093948822715447	P43307, P63159, P22105	103	76	5048	4.514052120592743	0.9645387421511411	0.03662059716143268	0.032661613684521036
GOTERM_MF_DIRECT	GO:0000976~transcription cis-regulatory region binding	6	5.042016806722689	0.004276580740807984	A4UTP7, P63159	102	53	4937	5.479467258601554	0.6746542723127724	0.037348805136389725	0.03392754054374334
UP_KW_LIGAND	KW-0106~Calcium	13	10.92436974789916	0.004584430186679041	Q9VAF5, P24044, Q3KQ77, Q9VDG5, P28491, P37889, Q8CIY2, O75096, P54315, Q8HZK2, Q28EB4, Q9D4D4, P43307	43	281	2206	2.3734171977157987	0.11260869979761101	0.11919518485365506	0.11919518485365506
GOTERM_BP_DIRECT	GO:0046330~positive regulation of JNK cascade	5	4.201680672268908	0.0050856887731708	P63159	103	35	5048	7.0013869625520115	0.984240520634303	0.04499728979740251	0.04013271792741305
GOTERM_BP_DIRECT	GO:0007399~nervous system development	8	6.722689075630252	0.005590076738012526	P29617, P63159, O88572, P43006	103	107	5048	3.6642772888122668	0.9895702021092763	0.04892819854561501	0.04363866356771069
GOTERM_BP_DIRECT	GO:0042554~superoxide anion generation	3	2.5210084033613445	0.005751873607095929	O46522, Q8CIY2, Q8HZK2	103	6	5048	24.50485436893204	0.9908640873002486	0.04980877783166049	0.044424045093102604
UP_SEQ_FEATURE	DOMAIN:VWFA 2	3	2.5210084033613445	0.005890586163531347	P15989, A6NMZ7, A2AX52	107	6	5183	24.2196261682243	0.9686358702358578	0.09083903925866761	0.08696365362476542
UP_SEQ_FEATURE	REGION:Triple-helical region	3	2.5210084033613445	0.005890586163531347	P15989, A6NMZ7, A2AX52	107	6	5183	24.2196261682243	0.9686358702358578	0.09083903925866761	0.08696365362476542
UP_SEQ_FEATURE	REGION:Nonhelical region	3	2.5210084033613445	0.005890586163531347	P15989, A6NMZ7, A2AX52	107	6	5183	24.2196261682243	0.9686358702358578	0.09083903925866761	0.08696365362476542
UP_SEQ_FEATURE	DOMAIN:VWFA 1	3	2.5210084033613445	0.005890586163531347	P15989, A6NMZ7, A2AX52	107	6	5183	24.2196261682243	0.9686358702358578	0.09083903925866761	0.08696365362476542
GOTERM_CC_DIRECT	GO:0043005~neuron projection	8	6.722689075630252	0.006423584232845449	P15146, Q24524, Q8BSK8, P63159	109	107	5213	3.5757523793192147	0.7498076880880686	0.13260643116060633	0.12828901247165636
GOTERM_MF_DIRECT	GO:0003690~double-stranded DNA binding	5	4.201680672268908	0.006492146566575338	P63159	102	37	4937	6.540805511393747	0.8184978533688823	0.05486910969170124	0.04984293170467517
UP_SEQ_FEATURE	CARBOHYD:N-linked (GlcNAc...) asparagine	25	21.008403361344538	0.00711230317624994	O46522, A4IGY6, A4QP81, Q9VDG5, P15989, Q8N2E2, Q8CIY2, Q8HZK2, Q5RBP9, Q9I9M5, O88572, Q9VAF5, Q9GMB0, P37889, Q8TCJ2, O75096, Q9H1V8, A2AX52, Q6P5E4, Q1HG43, P43307, Q8NBI5, A6NMZ7, P22105, P43006	107	705	5183	1.717703983562007	0.9847427682811659	0.10686691439185808	0.10230774568913376
UP_KW_BIOLOGICAL_PROCESS	KW-0233~DNA recombination	5	4.201680672268908	0.007119311105265432	P63159	76	33	3159	6.297846889952153	0.38041159224874255	0.09063717147901824	0.08522599706236043
GOTERM_BP_DIRECT	GO:0065003~protein-containing complex assembly	5	4.201680672268908	0.007512023586929727	P63159	103	39	5048	6.283295992033856	0.9978404816855088	0.06436618105011366	0.05740767499064191
GOTERM_CC_DIRECT	GO:0005581~collagen trimer	4	3.361344537815126	0.007627210147531439	Q641F3, P15989, A6NMZ7, A2AX52	109	20	5213	9.5651376146789	0.8072065566254809	0.13260643116060633	0.12828901247165636
GOTERM_MF_DIRECT	GO:0003714~transcription corepressor activity	6	5.042016806722689	0.007797034855692307	Q9UKV0, P63159	102	61	4937	4.760848601735776	0.8713717418241602	0.06383822288098076	0.05799044673921153
GOTERM_CC_DIRECT	GO:0005694~chromosome	9	7.563025210084033	0.007806621443005603	O42130, Q86NP2, Q24537, P63159, E9PVX6	109	139	5213	3.0966272853277013	0.8145572956831503	0.13260643116060633	0.12828901247165636
GOTERM_BP_DIRECT	GO:0042744~hydrogen peroxide catabolic process	3	2.5210084033613445	0.007946886433569588	Q8CIY2, P0CB50, Q8HZK2	103	7	5048	21.004160887656035	0.9984884290736321	0.0673829745513088	0.06009832865387001
UP_KW_DOMAIN	KW-0176~Collagen	4	3.361344537815126	0.008023822488245156	Q641F3, P15989, A6NMZ7, A2AX52	76	20	3542	9.321052631578947	0.11382674391061498	0.06017866866183867	0.06017866866183867
UP_KW_BIOLOGICAL_PROCESS	KW-0029~Amino-acid transport	4	3.361344537815126	0.008116761624986708	Q9N1R6, Q9H1V8, P43006	76	18	3159	9.236842105263158	0.42076214675149726	0.09063717147901824	0.08522599706236043
KEGG_PATHWAY	rno04140:Autophagy - animal	4	3.361344537815126	0.00850682261179591	P63159	63	17	2412	9.008403361344538	0.8549629345229927	0.4806354775664689	0.4785087719135199
GOTERM_CC_DIRECT	GO:0016324~apical plasma membrane	8	6.722689075630252	0.0085997651582768	Q9N1R6, Q9VAF5, A4IGY6, Q8CIY2, O75096, Q8HZK2, O88572	109	113	5213	3.385889421125274	0.8438511642283697	0.13260643116060633	0.12828901247165636
GOTERM_CC_DIRECT	GO:0005615~extracellular space	11	9.243697478991598	0.008634837377899947	P82198, P15989, P63159, P19477, Q9H4G4, P22105, P54315	109	202	5213	2.6043691525115813	0.8450343380077534	0.13260643116060633	0.12828901247165636
GOTERM_BP_DIRECT	GO:0000122~negative regulation of transcription by RNA polymerase II	11	9.243697478991598	0.009111745528472652	Q86NP2, A4UTP7, Q24537, P29617, Q9UKV0, A2VDZ3, P63159	103	209	5048	2.5794583546244247	0.9994191152959983	0.07646351402244062	0.06819718818217675
GOTERM_CC_DIRECT	GO:0005769~early endosome	8	6.722689075630252	0.010325173781388853	Q9UL25, P63159, Q3UVU3, O88572	109	117	5213	3.27013251783894	0.8926276261966586	0.14799415753324024	0.14317574310192543
GOTERM_BP_DIRECT	GO:0015804~neutral amino acid transport	3	2.5210084033613445	0.010456934328404199	Q9N1R6, Q9H1V8	103	8	5048	18.37864077669903	0.9998077591745786	0.08685657697266344	0.07746667675940253
GOTERM_MF_DIRECT	GO:0015175~neutral L-amino acid transmembrane transporter activity	3	2.5210084033613445	0.010707640630351395	Q9N1R6, P43006	102	8	4937	18.150735294117645	0.9404256131104303	0.08501217712582017	0.07722480212192824
GOTERM_BP_DIRECT	GO:0030036~actin cytoskeleton organization	7	5.88235294117647	0.010845528906993957	Q24524, P63159, P22105	103	93	5048	3.688902808226328	0.9998603656155137	0.0891743487908392	0.07953387865128903
GOTERM_MF_DIRECT	GO:0005509~calcium ion binding	11	9.243697478991598	0.011916154569212838	Q9VAF5, P24044, Q3KQ77, Q9VDG5, P28491, P37889, Q8N2E2, Q8CIY2, O75096, P54315, Q8HZK2	102	215	4937	2.4763793889648884	0.9567510754637544	0.09182448520981658	0.08341308198448986
SMART	SM00327:VWA	4	3.361344537815126	0.014457498370808222	Q641F3, P15989, A6NMZ7, A2AX52	62	26	3035	7.531017369727047	0.6596102348388706	0.5349274397199042	0.5349274397199042
GOTERM_BP_DIRECT	GO:0030335~positive regulation of cell migration	5	4.201680672268908	0.015481043082736541	P63159	103	48	5048	5.105177993527508	0.9999969492720698	0.12601569069347546	0.11239237278066729
GOTERM_BP_DIRECT	GO:0048813~dendrite morphogenesis	4	3.361344537815126	0.0164800653593229	P15146, P29617, A2VDZ3, O75096	103	27	5048	7.260697590794678	0.9999986649489595	0.13281953665830534	0.11846066783038045
UP_KW_PTM	KW-1015~Disulfide bond	21	17.647058823529413	0.016527802079151437	P28491, P15989, P37889, Q8N2E2, P19477, O75096, P54315, Q8HZK2, Q9N1R6, Q5RBP9, P82198, P63159, P22105, P0CB50, Q9I9M5, O88572	83	522	3470	1.6819000138484972	0.2591716901340916	0.07850705987596933	0.07024315883639361
INTERPRO	IPR039261:FNR_nucleotide-bd	3	2.5210084033613445	0.019199132851370645	O46522, Q8CIY2, Q8HZK2	108	11	5376	13.575757575757574	0.9996107392066654	0.7758961210672267	0.7739803281757026
INTERPRO	IPR017927:FAD-bd_FR_type	3	2.5210084033613445	0.019199132851370645	O46522, Q8CIY2, Q8HZK2	108	11	5376	13.575757575757574	0.9996107392066654	0.7758961210672267	0.7739803281757026
INTERPRO	IPR017938:Riboflavin_synthase-like_b-brl	3	2.5210084033613445	0.019199132851370645	O46522, Q8CIY2, Q8HZK2	108	11	5376	13.575757575757574	0.9996107392066654	0.7758961210672267	0.7739803281757026
GOTERM_BP_DIRECT	GO:0006952~defense response	3	2.5210084033613445	0.019745551556764954	O46522, Q8CIY2, Q8HZK2	103	11	5048	13.366284201235658	0.999999910915742	0.157577244776536	0.14054186696285642
UP_SEQ_FEATURE	DOMAIN:FAD-binding FR-type	3	2.5210084033613445	0.020204655671584835	O46522, Q8CIY2, Q8HZK2	107	11	5183	13.2107051826678	0.9999936125472911	0.2959982055887178	0.2833702957939773
GOTERM_BP_DIRECT	GO:0001934~positive regulation of protein phosphorylation	5	4.201680672268908	0.02026334495947097	P63159	103	52	5048	4.712471994025392	0.9999999420549506	0.16013944463115892	0.14282707223860122
GOTERM_BP_DIRECT	GO:0045087~innate immune response	7	5.88235294117647	0.020530643437320403	O46522, Q9EPL8, P63159	103	107	5048	3.2062426277107337	0.9999999535960877	0.16069176690364237	0.1433196839951405
INTERPRO	IPR002035:VWF_A	4	3.361344537815126	0.02107372180676418	Q641F3, P15989, A6NMZ7, A2AX52	108	30	5376	6.637037037037037	0.9998206321255367	0.7758961210672267	0.7739803281757026
UP_KW_CELLULAR_COMPONENT	KW-0158~Chromosome	10	8.403361344537815	0.02140762922565259	P49454, Q86NP2, Q24537, Q6P823, P63159, E9PVX6	102	193	4724	2.3996748958650818	0.48872260197134987	0.1666087655615778	0.1666087655615778
UP_KW_MOLECULAR_FUNCTION	KW-0575~Peroxidase	3	2.5210084033613445	0.024713049692258137	Q8CIY2, P0CB50, Q8HZK2	69	12	3261	11.815217391304348	0.6590475863628078	0.2510281597872586	0.2510281597872586
UP_KW_CELLULAR_COMPONENT	KW-1003~Cell membrane	23	19.327731092436977	0.026806439014724216	O46522, Q9VAF5, A4IGY6, Q9VDG5, Q8CIY2, Q9ULC3, Q5RKJ1, O75096, Q3UVU3, Q8HZK2, Q9N1R6, Q5NVM9, Q8NBI5, O01393, P63159, Q9I9M5, O88572, P43006	102	678	4724	1.5711145815258258	0.5692988501663194	0.1666087655615778	0.1666087655615778
UP_KW_CELLULAR_COMPONENT	KW-0967~Endosome	11	9.243697478991598	0.026872381542189967	Q9UL25, Q9VAF5, A4IGY6, Q99805, P63159, Q9ULC3, Q3UVU3	102	234	4724	2.177140941846824	0.5702026301989558	0.1666087655615778	0.1666087655615778
UP_KW_MOLECULAR_FUNCTION	KW-0560~Oxidoreductase	10	8.403361344537815	0.026992177215057884	Q9Z0R9, O46522, Q9NWM0, Q3MHG7, A4QP81, Q8CIY2, C3ZAH2, P0CB50, Q3T145, Q8HZK2	69	208	3261	2.272157190635452	0.6916795915608182	0.2510281597872586	0.2510281597872586
UP_SEQ_FEATURE	TOPO_DOM:Extracellular	15	12.605042016806722	0.02817952360642034	O46522, Q9VAF5, A4IGY6, Q16932, Q9VDG5, Q8CIY2, O75096, Q9H1V8, Q3UVU3, Q8HZK2, Q9N1R6, Q1HG43, Q9I9M5, O88572	107	393	5183	1.8488264250552897	0.999999946859866	0.40276099593566633	0.3855783595902881
UP_KW_BIOLOGICAL_PROCESS	KW-0391~Immunity	8	6.722689075630252	0.02836030341473318	O62703, Q9VAF5, Q5RBP9, P63159	76	126	3159	2.6390977443609023	0.8545037733497124	0.2714486183981604	0.2552427307325986
UP_KW_MOLECULAR_FUNCTION	KW-9996~Developmental protein	13	10.92436974789916	0.02918932090549519	P49454, Q28J24, Q86NP2, P55937, A2VDZ3, Q9ULC3, O75096, Q28EB4, Q24524, A4UTP7, P29617, Q9I9M5, O88572	69	318	3261	1.9320481268799563	0.7202401185921133	0.2510281597872586	0.2510281597872586
UP_KW_MOLECULAR_FUNCTION	KW-0217~Developmental protein	13	10.92436974789916	0.02918932090549519	P49454, Q28J24, Q86NP2, P55937, A2VDZ3, Q9ULC3, O75096, Q28EB4, Q24524, A4UTP7, P29617, Q9I9M5, O88572	69	318	3261	1.9320481268799563	0.7202401185921133	0.2510281597872586	0.2510281597872586
UP_SEQ_FEATURE	DOMAIN:EGF-like 3	4	3.361344537815126	0.03388874062705925	Q8N2E2, P22105, O75096, O88572	107	35	5183	5.535914552736982	0.9999999983176896	0.47282861922516006	0.45265674980429144
GOTERM_BP_DIRECT	GO:0006366~transcription by RNA polymerase II	5	4.201680672268908	0.03406580684220245	P63159	103	61	5048	4.017189240808531	0.9999999999994411	0.264091112090979	0.23554072159465694
GOTERM_CC_DIRECT	GO:0005576~extracellular region	11	9.243697478991598	0.03582828660229488	P20481, Q641F3, P82198, P28491, P15989, P37889, A6NMZ7, Q8N2E2, P22105, P54315, A2AX52	109	253	5213	2.0793777423215	0.9996080839797276	0.4814426012183375	0.46576772582983345
GOTERM_BP_DIRECT	GO:0007155~cell adhesion	6	5.042016806722689	0.0376372568288386	P82198, P15989, A6NMZ7, Q5RKJ1, P22105, A2AX52	103	92	5048	3.196285352469397	0.9999999999999726	0.2890257269686285	0.25777970243147946
INTERPRO	IPR033896:MADS_MEF2-like	2	1.680672268907563	0.03941403654449933	A4UTP7, A2VDZ3	108	2	5376	49.77777777777778	0.9999999154379169	1.0	1.0
INTERPRO	IPR036879:TF_MADSbox_sf	2	1.680672268907563	0.03941403654449933	A4UTP7, A2VDZ3	108	2	5376	49.77777777777778	0.9999999154379169	1.0	1.0
INTERPRO	IPR022102:HJURP_C	2	1.680672268907563	0.03941403654449933	A4UTP7, A2VDZ3	108	2	5376	49.77777777777778	0.9999999154379169	1.0	1.0
INTERPRO	IPR002100:TF_MADSbox	2	1.680672268907563	0.03941403654449933	A4UTP7, A2VDZ3	108	2	5376	49.77777777777778	0.9999999154379169	1.0	1.0
SMART	SM00432:MADS	2	1.680672268907563	0.039800221324545575	A4UTP7, A2VDZ3	62	2	3035	48.95161290322581	0.9504825224740716	0.7435176212033692	0.7435176212033692
SMART	SM00181:EGF	5	4.201680672268908	0.0401901416866686	P37889, Q8N2E2, P22105, O75096, O88572	62	65	3035	3.7655086848635233	0.9519486861810839	0.7435176212033692	0.7435176212033692
GOTERM_BP_DIRECT	GO:0018279~protein N-linked glycosylation via asparagine	3	2.5210084033613445	0.04035566288426469	Q9GMB0, Q8TCJ2, Q6P5E4	103	16	5048	9.189320388349515	0.9999999999999972	0.3070047625027239	0.27381505844837534
UP_SEQ_FEATURE	DNA_BIND:Mef2-type	2	1.680672268907563	0.04048855501170463	A4UTP7, A2VDZ3	107	2	5183	48.4392523364486	0.9999999999697035	0.5392339372013389	0.5162290763992341
UP_SEQ_FEATURE	DOMAIN:MADS-box	2	1.680672268907563	0.04048855501170463	A4UTP7, A2VDZ3	107	2	5183	48.4392523364486	0.9999999999697035	0.5392339372013389	0.5162290763992341
GOTERM_MF_DIRECT	GO:0015184~L-cystine transmembrane transporter activity	2	1.680672268907563	0.040501075299441254	Q9N1R6	102	2	4937	48.40196078431372	0.9999802459113194	0.29223983333915515	0.2654697722699196
GOTERM_MF_DIRECT	GO:0180009~broad specificity neutral L-amino acid:basic L-amino acid antiporter activity	2	1.680672268907563	0.040501075299441254	Q9N1R6	102	2	4937	48.40196078431372	0.9999802459113194	0.29223983333915515	0.2654697722699196
GOTERM_MF_DIRECT	GO:0005518~collagen binding	3	2.5210084033613445	0.041270510815071534	P82198, P22105, A2AX52	102	16	4937	9.075367647058822	0.9999839906205562	0.29223983333915515	0.2654697722699196
UP_SEQ_FEATURE	TOPO_DOM:Cytoplasmic	22	18.487394957983195	0.042968457458494806	Q9Z0R9, O46522, Q9GMB0, Q9VAF5, A4IGY6, Q16932, Q9VDG5, Q8TCJ2, Q8CIY2, O75096, Q9H1V8, Q3UVU3, Q8HZK2, Q9N1R6, Q1HG43, P43307, A6QL88, Q99805, Q9I9M5, O88572, P43006	107	700	5183	1.5223765020026703	0.9999999999933505	0.5595448015706213	0.5356734363159019
UP_SEQ_FEATURE	DOMAIN:EGF-like 2	4	3.361344537815126	0.04464322724472469	P37889, Q8N2E2, P22105, O88572	107	39	5183	4.968128444763958	0.9999999999976175	0.5687158949001885	0.5444532713976207
GOTERM_CC_DIRECT	GO:0031526~brush border membrane	3	2.5210084033613445	0.04724007309414853	Q9N1R6, Q9VAF5	109	17	5213	8.439827307069617	0.9999696995748678	0.5974479832495255	0.5779961884460526
UP_KW_DOMAIN	KW-0245~EGF-like domain	5	4.201680672268908	0.04754881570996547	P37889, Q8N2E2, P22105, O75096, O88572	76	65	3542	3.58502024291498	0.5184505488616858	0.23774407854982735	0.23774407854982735
UP_KW_PTM	KW-0007~Acetylation	36	30.252100840336134	0.04839763564427366	P24044, Q3MHG7, Q68FD5, Q8BSK8, A2VDZ3, Q00341, Q3T145, Q5NVM9, O62703, Q8BHL8, Q5R5H1, Q8BN59, P31029, Q9GMB0, Q9UL25, Q9EPL8, P49454, Q8BGS2, P28491, P55937, Q8TCJ2, Q8BGD9, P11498, Q0MQC3, A4UTP7, Q6P823, A6QL88, Q98925, P63159, Q9TRY0, E9PVX6, Q5REU4	83	1160	3470	1.297465724968841	0.5905515574439313	0.18391101544823987	0.16455196119053042
KEGG_PATHWAY	mmu04150:mTOR signaling pathway	3	2.5210084033613445	0.04851221692520968	Q8BSK8, Q8BGD9, O88572	63	14	2412	8.204081632653061	0.999986843907869	1.0	1.0
INTERPRO	IPR000742:EGF-like_dom	5	4.201680672268908	0.04998425090854765	P37889, Q8N2E2, P22105, O75096, O88572	108	70	5376	3.5555555555555554	0.9999999990428589	1.0	1.0
GOTERM_CC_DIRECT	GO:0042470~melanosome	4	3.361344537815126	0.05221800391962921	Q5NVM9, Q9GMB0, Q68FD5, Q5REU4	109	41	5213	4.665920787648243	0.9999901753350177	0.6237150468177933	0.6034080452934931
UP_KW_BIOLOGICAL_PROCESS	KW-0399~Innate immunity	6	5.042016806722689	0.05395079192099112	Q5RBP9, P63159	76	87	3159	2.866606170598911	0.9756656541520855	0.45183788233830063	0.4248624863778051
GOTERM_MF_DIRECT	GO:0031072~heat shock protein binding	3	2.5210084033613445	0.05653687672526626	Q5NVM9, Q68FD5, Q9TRY0	102	19	4937	7.642414860681114	0.999999761256478	0.3898068868952568	0.354099385805615
UP_SEQ_FEATURE	TRANSMEM:Helical	29	24.369747899159663	0.05840625639353643	Q9Z0R9, O46522, A4IGY6, A4QP81, Q9VDG5, Q8CIY2, Q3UVU3, Q8HZK2, Q28EB4, Q5RBP9, Q99805, Q5RC32, Q9I9M5, O88572, Q9VAF5, Q9GMB0, Q3UMF9, Q16932, O57590, Q8TCJ2, O75096, Q9N1R6, Q1HG43, P43307, Q8NBI5, O01393, A6QL88, P43006	107	1027	5183	1.3678075148559	0.9999999999999996	0.7046011896479599	0.6745414119326033
INTERPRO	IPR034821:DUOX_peroxidase	2	1.680672268907563	0.05853995729076785	Q8CIY2, Q8HZK2	108	3	5376	33.18518518518518	0.9999999999754661	1.0	1.0
GOTERM_CC_DIRECT	GO:0005886~plasma membrane	29	24.369747899159663	0.0589313550998293	O46522, Q9VAF5, A4IGY6, Q8N2E2, Q8CIY2, Q9ULC3, Q00341, Q5RKJ1, O75096, Q3UVU3, Q9H1V8, Q8HZK2, Q9N1R6, Q5NVM9, Q1HG43, Q91WA3, P84770, O01393, P29617, Q99805, P63159, Q9I9M5, O88572, P43006	109	1014	5213	1.3677958127499414	0.9999978690156145	0.6668548077085947	0.6451432558297103
GOTERM_BP_DIRECT	GO:0072318~clathrin coat disassembly	2	1.680672268907563	0.059412998075880984	Q5NVM9, Q68FD5	103	3	5048	32.67313915857605	1.0	0.4396561857615193	0.3921257873008145
GOTERM_BP_DIRECT	GO:0055071~manganese ion homeostasis	2	1.680672268907563	0.059412998075880984	A4IGY6, Q3UVU3	103	3	5048	32.67313915857605	1.0	0.4396561857615193	0.3921257873008145
GOTERM_BP_DIRECT	GO:0015811~L-cystine transport	2	1.680672268907563	0.059412998075880984	Q9N1R6	103	3	5048	32.67313915857605	1.0	0.4396561857615193	0.3921257873008145
INTERPRO	IPR036465:vWFA_dom_sf	4	3.361344537815126	0.05954825378895131	Q641F3, P15989, A6NMZ7, A2AX52	108	45	5376	4.424691358024691	0.9999999999841039	1.0	1.0
UP_SEQ_FEATURE	DOMAIN:VWFA 9	2	1.680672268907563	0.0601195554307133	P15989, A6NMZ7	107	3	5183	32.29283489096573	0.9999999999999999	0.7046011896479599	0.6745414119326033
UP_SEQ_FEATURE	REGION:Peroxidase-like; mediates peroxidase activity	2	1.680672268907563	0.0601195554307133	Q8CIY2, Q8HZK2	107	3	5183	32.29283489096573	0.9999999999999999	0.7046011896479599	0.6745414119326033
UP_SEQ_FEATURE	REGION:Interaction with TXNDC11	2	1.680672268907563	0.0601195554307133	Q8CIY2, Q8HZK2	107	3	5183	32.29283489096573	0.9999999999999999	0.7046011896479599	0.6745414119326033
GOTERM_MF_DIRECT	GO:0106293~NADH oxidase H202-forming activity	2	1.680672268907563	0.0601382366766762	Q8CIY2, Q8HZK2	102	3	4937	32.267973856209146	0.9999999123477368	0.40400558998177344	0.3669974443345881
KEGG_PATHWAY	mmu05225:Hepatocellular carcinoma	3	2.5210084033613445	0.06191471960911188	Q8R5I6, Q8BSK8, O88572	63	16	2412	7.178571428571428	0.9999994669540506	1.0	1.0
GOTERM_MF_DIRECT	GO:0003676~nucleic acid binding	7	5.88235294117647	0.06242745429937913	Q8BN59, P63159, Q8BGD9	102	138	4937	2.4551719238420007	0.9999999537321831	0.4088998256609333	0.3714433530813058
GOTERM_BP_DIRECT	GO:0006325~chromatin organization	6	5.042016806722689	0.0644281847703738	Q91WA3, P63159	103	107	5048	2.7482079666092005	1.0	0.47247335498274123	0.4213951544440665
GOTERM_MF_DIRECT	GO:0046982~protein heterodimerization activity	5	4.201680672268908	0.0665923239478678	Q8BHL8, Q28J24, A4UTP7, Q6P823, A2VDZ3	102	75	4937	3.226797385620915	0.9999999855888568	0.4255411920571064	0.38656031950225694
UP_KW_PTM	KW-0325~Glycoprotein	25	21.008403361344538	0.06782000849479375	O46522, A4IGY6, A4QP81, Q9VDG5, P15989, Q8N2E2, Q8CIY2, Q8HZK2, Q5RBP9, Q9I9M5, O88572, Q9VAF5, Q9GMB0, P37889, Q8TCJ2, O75096, Q9H1V8, A2AX52, Q6P5E4, Q1HG43, P43307, Q8NBI5, A6NMZ7, P22105, P43006	83	757	3470	1.3806878770033901	0.71751461441578	0.21476336023351353	0.19215669073524896
GOTERM_BP_DIRECT	GO:0036503~ERAD pathway	4	3.361344537815126	0.06853342931406654	P28491, P23787, Q8TCJ2, Q6P5E4	103	47	5048	4.171039041520347	1.0	0.49809117376473366	0.4442434793036813
KEGG_PATHWAY	mmu04151:PI3K-Akt signaling pathway	3	2.5210084033613445	0.06903577254219109	Q8BSK8, Q8BGD9, A2AX52	63	17	2412	6.756302521008403	0.9999999047518577	1.0	1.0
UP_KW_BIOLOGICAL_PROCESS	KW-0893~Thyroid hormones biosynthesis	2	1.680672268907563	0.06956895012500933	Q8CIY2, Q8HZK2	76	3	3159	27.71052631578947	0.992022972922731	0.5179021842639583	0.4869826508750653
UP_SEQ_FEATURE	MOTIF:Nuclear localization signal	7	5.88235294117647	0.06977601232816727	O62703, Q28EB4, P49454, Q28J24, P29617, Q8BN59, Q5REU4	107	142	5183	2.3878504672897196	1.0	0.8017400632216867	0.76753613560984
GOTERM_BP_DIRECT	GO:0006898~receptor-mediated endocytosis	3	2.5210084033613445	0.0718756534953653	Q68FD5, O75096, O88572	103	22	5048	6.683142100617829	1.0	0.5177591322586492	0.46178517201447083
GOTERM_CC_DIRECT	GO:0031012~extracellular matrix	4	3.361344537815126	0.07275086431470609	P82198, A6NMZ7, P22105, A2AX52	109	47	5213	4.070271325395276	0.9999999114407369	0.7820717913830905	0.7566089888729434
KEGG_PATHWAY	ocu04974:Protein digestion and absorption	2	1.680672268907563	0.07517956974353272	Q9N1R6	63	3	2412	25.523809523809522	0.9999999786707376	1.0	1.0
INTERPRO	IPR010255:Haem_peroxidase_sf	2	1.680672268907563	0.07728855668974281	Q8CIY2, Q8HZK2	108	4	5376	24.88888888888889	0.9999999999999929	1.0	1.0
INTERPRO	IPR037120:Haem_peroxidase_sf_animal	2	1.680672268907563	0.07728855668974281	Q8CIY2, Q8HZK2	108	4	5376	24.88888888888889	0.9999999999999929	1.0	1.0
INTERPRO	IPR019791:Haem_peroxidase_animal	2	1.680672268907563	0.07728855668974281	Q8CIY2, Q8HZK2	108	4	5376	24.88888888888889	0.9999999999999929	1.0	1.0
GOTERM_BP_DIRECT	GO:0042446~hormone biosynthetic process	2	1.680672268907563	0.07842982150421528	Q8CIY2, Q8HZK2	103	4	5048	24.504854368932037	1.0	0.5456570487558225	0.48666709753897686
GOTERM_BP_DIRECT	GO:0042335~cuticle development	2	1.680672268907563	0.07842982150421528	Q8CIY2, Q8HZK2	103	4	5048	24.504854368932037	1.0	0.5456570487558225	0.48666709753897686
GOTERM_BP_DIRECT	GO:0006590~thyroid hormone generation	2	1.680672268907563	0.07842982150421528	Q8CIY2, Q8HZK2	103	4	5048	24.504854368932037	1.0	0.5456570487558225	0.48666709753897686
GOTERM_BP_DIRECT	GO:0030279~negative regulation of ossification	2	1.680672268907563	0.07842982150421528	A4UTP7, O75096	103	4	5048	24.504854368932037	1.0	0.5456570487558225	0.48666709753897686
UP_SEQ_FEATURE	DOMAIN:Histone deacetylase	2	1.680672268907563	0.07935263016558315	Q91WA3, Q9UKV0	107	4	5183	24.2196261682243	1.0	0.877370590132674	0.8399401042055122
UP_SEQ_FEATURE	REGION:Histone deacetylase	2	1.680672268907563	0.07935263016558315	Q91WA3, Q9UKV0	107	4	5183	24.2196261682243	1.0	0.877370590132674	0.8399401042055122
GOTERM_MF_DIRECT	GO:0016174~NAD(P)H oxidase H2O2-forming activity	2	1.680672268907563	0.07937740126833703	Q8CIY2, Q8HZK2	102	4	4937	24.20098039215686	0.9999999996115032	0.4836483519140536	0.43934468608986543
GOTERM_MF_DIRECT	GO:0042605~peptide antigen binding	2	1.680672268907563	0.07937740126833703	Q9N1R6	102	4	4937	24.20098039215686	0.9999999996115032	0.4836483519140536	0.43934468608986543
UP_SEQ_FEATURE	DOMAIN:EF-hand 3	4	3.361344537815126	0.08168017903673873	P24044, Q3KQ77, Q8CIY2, Q8HZK2	107	50	5183	3.8751401869158877	1.0	0.886381202139424	0.8485663044372301
GOTERM_BP_DIRECT	GO:0032869~cellular response to insulin stimulus	3	2.5210084033613445	0.08369569967235026	A4IGY6, Q8BSK8, Q9UKV0	103	24	5048	6.12621359223301	1.0	0.5773584706211281	0.5149413386620871
UP_KW_LIGAND	KW-0274~FAD	4	3.361344537815126	0.08503110916933211	O46522, Q9NWM0, Q8CIY2, Q8HZK2	43	55	2206	3.7310782241014797	0.9007879249491183	0.867241388735792	0.867241388735792
GOTERM_MF_DIRECT	GO:0005201~extracellular matrix structural constituent	3	2.5210084033613445	0.0854868147145052	P82198, P37889, P22105	102	24	4937	6.050245098039215	0.9999999999321152	0.4977232323377858	0.4521302644900497
GOTERM_MF_DIRECT	GO:0042826~histone deacetylase binding	3	2.5210084033613445	0.0854868147145052	A4UTP7, Q9UKV0, A2VDZ3	102	24	4937	6.050245098039215	0.9999999999321152	0.4977232323377858	0.4521302644900497
UP_KW_BIOLOGICAL_PROCESS	KW-0249~Electron transport	4	3.361344537815126	0.08974005522459165	Q9Z0R9, O46522, Q0MQC3, A4QP81	76	45	3159	3.694736842105263	0.9981631065313	0.5584142662576008	0.5250761011078934
UP_KW_BIOLOGICAL_PROCESS	KW-0376~Hydrogen peroxide	2	1.680672268907563	0.09167995416169566	Q8CIY2, Q8HZK2	76	4	3159	20.782894736842103	0.9984077684710093	0.5584142662576008	0.5250761011078934
INTERPRO	IPR023801:His_deacetylse_dom	2	1.680672268907563	0.09566720978596475	Q91WA3, Q9UKV0	108	5	5376	19.91111111111111	1.0	1.0	1.0
INTERPRO	IPR037138:His_deacetylse_dom_sf	2	1.680672268907563	0.09566720978596475	Q91WA3, Q9UKV0	108	5	5376	19.91111111111111	1.0	1.0	1.0
INTERPRO	IPR002293:AA/rel_permease1	2	1.680672268907563	0.09566720978596475	Q9N1R6	108	5	5376	19.91111111111111	1.0	1.0	1.0
INTERPRO	IPR000286:His_deacetylse	2	1.680672268907563	0.09566720978596475	Q91WA3, Q9UKV0	108	5	5376	19.91111111111111	1.0	1.0	1.0
GOTERM_BP_DIRECT	GO:0014033~neural crest cell differentiation	2	1.680672268907563	0.0970658560417506	A4UTP7, O88572	103	5	5048	19.603883495145627	1.0	0.6529884860990495	0.5823951362505035
GOTERM_BP_DIRECT	GO:0050771~negative regulation of axonogenesis	2	1.680672268907563	0.0970658560417506	P29617, O75096	103	5	5048	19.603883495145627	1.0	0.6529884860990495	0.5823951362505035
GOTERM_BP_DIRECT	GO:0048821~erythrocyte development	2	1.680672268907563	0.0970658560417506	Q9XS79, Q5RKJ1	103	5	5048	19.603883495145627	1.0	0.6529884860990495	0.5823951362505035
UP_SEQ_FEATURE	DOMAIN:EGF-like	4	3.361344537815126	0.0976106669003368	P37889, Q8N2E2, P22105, O88572	107	54	5183	3.588092765662859	1.0	0.9628294192203206	0.9217530788098972
UP_SEQ_FEATURE	SITE:Interaction with DNA	2	1.680672268907563	0.09819576999904454	O42130, P29617	107	5	5183	19.375700934579438	1.0	0.9628294192203206	0.9217530788098972
GOTERM_MF_DIRECT	GO:0005384~manganese ion transmembrane transporter activity	2	1.680672268907563	0.09822655644242283	A4IGY6, Q3UVU3	102	5	4937	19.360784313725492	0.99999999999828	0.5475608039981869	0.49740256241056663
GOTERM_MF_DIRECT	GO:0106294~NADPH oxidase H202-forming activity	2	1.680672268907563	0.09822655644242283	Q8CIY2, Q8HZK2	102	5	4937	19.360784313725492	0.99999999999828	0.5475608039981869	0.49740256241056663
KEGG_PATHWAY	ssc04141:Protein processing in endoplasmic reticulum	2	1.680672268907563	0.09898150692734337	Q9GMB0, P28491	63	4	2412	19.142857142857142	0.9999999999411404	1.0	1.0