CpG context (R1) ================ position count methylated count unmethylated % methylation coverage 1 221060 431252 33.89 652312 2 205451 464760 30.65 670211 3 189812 412143 31.53 601955 4 195671 320297 37.92 515968 5 187001 273891 40.57 460892 6 183320 231555 44.19 414875 7 199132 225626 46.88 424758 8 94977 264815 26.40 359792 9 86095 241435 26.29 327530 10 87662 231061 27.50 318723 11 92032 237254 27.95 329286 12 88942 241401 26.92 330343 13 86577 244943 26.12 331520 14 81027 244786 24.87 325813 15 78228 246327 24.10 324555 16 72109 242489 22.92 314598 17 67358 235953 22.21 303311 18 69258 240474 22.36 309732 19 68700 242806 22.05 311506 20 68957 246445 21.86 315402 21 69646 249259 21.84 318905 22 67812 246913 21.55 314725 23 67107 243561 21.60 310668 24 66640 243046 21.52 309686 25 64619 241789 21.09 306408 26 64808 237853 21.41 302661 27 64723 246253 20.81 310976 28 66348 244150 21.37 310498 29 64806 245471 20.89 310277 30 63577 243088 20.73 306665 31 65023 240023 21.32 305046 32 63665 235575 21.28 299240 33 64579 238709 21.29 303288 34 65832 238640 21.62 304472 35 64319 236632 21.37 300951 36 63396 239187 20.95 302583 37 61703 233449 20.91 295152 38 61817 234017 20.90 295834 39 63444 237571 21.08 301015 40 63073 234335 21.21 297408 41 62849 237095 20.95 299944 42 64158 241007 21.02 305165 43 63945 239977 21.04 303922 44 63171 236253 21.10 299424 45 63764 238020 21.13 301784 46 64343 239731 21.16 304074 47 63426 235285 21.23 298711 48 63110 235566 21.13 298676 49 65176 235618 21.67 300794 50 62824 239685 20.77 302509 51 63380 237386 21.07 300766 52 64073 244226 20.78 308299 53 62558 235197 21.01 297755 54 61958 233477 20.97 295435 55 61378 228905 21.14 290283 56 61555 227494 21.30 289049 57 61910 230339 21.18 292249 58 62720 230728 21.37 293448 59 63745 229927 21.71 293672 60 61535 232112 20.96 293647 61 63294 228485 21.69 291779 62 61344 231662 20.94 293006 63 60820 228207 21.04 289027 64 60218 228598 20.85 288816 65 61257 225264 21.38 286521 66 62076 227236 21.46 289312 67 61009 222864 21.49 283873 68 60288 222544 21.32 282832 69 58962 220383 21.11 279345 70 58869 219508 21.15 278377 71 57898 218200 20.97 276098 72 57366 217414 20.88 274780 73 57395 214464 21.11 271859 74 57654 212780 21.32 270434 75 55443 212683 20.68 268126 76 55497 210177 20.89 265674 77 56142 210530 21.05 266672 78 55925 211544 20.91 267469 79 54920 207820 20.90 262740 80 54334 207185 20.78 261519 81 53529 205904 20.63 259433 82 52439 204036 20.45 256475 83 53117 205278 20.56 258395 84 52882 206226 20.41 259108 85 52368 203249 20.49 255617 86 51715 200747 20.48 252462 87 50602 199654 20.22 250256 88 50626 198810 20.30 249436 89 49720 196066 20.23 245786 90 49809 196920 20.19 246729 91 49700 194442 20.36 244142 92 48437 192807 20.08 241244 93 48516 192713 20.11 241229 94 48477 191623 20.19 240100 95 47638 188688 20.16 236326 96 47565 191374 19.91 238939 97 46854 182914 20.39 229768 98 43667 172682 20.18 216349 99 34285 137146 20.00 171431 100 44535 173824 20.40 218359 101 40278 172294 18.95 212572 CHG context (R1) ================ position count methylated count unmethylated % methylation coverage 1 371779 440863 45.75 812642 2 219660 399500 35.48 619160 3 82013 395442 17.18 477455 4 36235 408271 8.15 444506 5 21678 377624 5.43 399302 6 17544 361412 4.63 378956 7 14787 462725 3.10 477512 8 6409 501586 1.26 507995 9 5441 465892 1.15 471333 10 5479 441411 1.23 446890 11 5898 444240 1.31 450138 12 5572 443683 1.24 449255 13 4895 426968 1.13 431863 14 4522 425424 1.05 429946 15 4402 437285 1.00 441687 16 3961 436495 0.90 440456 17 4053 430892 0.93 434945 18 4243 430115 0.98 434358 19 3538 430537 0.82 434075 20 3625 451555 0.80 455180 21 3674 458301 0.80 461975 22 3784 453707 0.83 457491 23 3875 458120 0.84 461995 24 3678 461841 0.79 465519 25 3575 448471 0.79 452046 26 4205 452728 0.92 456933 27 3701 457838 0.80 461539 28 3639 456047 0.79 459686 29 3995 459808 0.86 463803 30 3709 466236 0.79 469945 31 3538 455558 0.77 459096 32 3474 458136 0.75 461610 33 3563 461769 0.77 465332 34 3497 454021 0.76 457518 35 3779 456239 0.82 460018 36 3561 456180 0.77 459741 37 3557 446775 0.79 450332 38 3613 451918 0.79 455531 39 3616 450082 0.80 453698 40 3557 449773 0.78 453330 41 3506 449375 0.77 452881 42 3513 452043 0.77 455556 43 3389 445859 0.75 449248 44 3457 452799 0.76 456256 45 3628 452178 0.80 455806 46 3442 448196 0.76 451638 47 3558 449333 0.79 452891 48 3526 456796 0.77 460322 49 3497 447678 0.78 451175 50 3698 448018 0.82 451716 51 3579 452345 0.78 455924 52 3606 451503 0.79 455109 53 3698 450662 0.81 454360 54 3794 455217 0.83 459011 55 3751 449688 0.83 453439 56 3798 453736 0.83 457534 57 3843 453388 0.84 457231 58 4463 447359 0.99 451822 59 4117 451148 0.90 455265 60 4116 453456 0.90 457572 61 4239 448044 0.94 452283 62 4373 450859 0.96 455232 63 4354 447666 0.96 452020 64 4386 443864 0.98 448250 65 4714 443654 1.05 448368 66 4507 437596 1.02 442103 67 4411 429307 1.02 433718 68 4645 432142 1.06 436787 69 4475 434134 1.02 438609 70 4285 428125 0.99 432410 71 4335 426433 1.01 430768 72 4209 425160 0.98 429369 73 4377 420593 1.03 424970 74 4357 416888 1.03 421245 75 4360 420230 1.03 424590 76 4177 411308 1.01 415485 77 4412 413922 1.05 418334 78 4139 406026 1.01 410165 79 4208 400508 1.04 404716 80 4186 399705 1.04 403891 81 4214 397094 1.05 401308 82 4143 391075 1.05 395218 83 4167 397376 1.04 401543 84 4261 396168 1.06 400429 85 4197 389713 1.07 393910 86 4236 391436 1.07 395672 87 4266 390215 1.08 394481 88 4270 384123 1.10 388393 89 4357 382466 1.13 386823 90 4183 382752 1.08 386935 91 4272 376730 1.12 381002 92 4518 379454 1.18 383972 93 4556 376899 1.19 381455 94 4552 369230 1.22 373782 95 4524 369636 1.21 374160 96 4653 366127 1.25 370780 97 4485 335211 1.32 339696 98 4111 310425 1.31 314536 99 2649 202899 1.29 205548 100 3021 205790 1.45 208811 101 5688 331718 1.69 337406 CHH context (R1) ================ position count methylated count unmethylated % methylation coverage 1 364852 504486 41.97 869338 2 170128 548402 23.68 718530 3 76025 679003 10.07 755028 4 61080 735381 7.67 796461 5 53368 881840 5.71 935208 6 43003 967095 4.26 1010098 7 37718 1239825 2.95 1277543 8 22796 1337778 1.68 1360574 9 18208 1212459 1.48 1230667 10 17998 1177185 1.51 1195183 11 20053 1183233 1.67 1203286 12 18142 1204689 1.48 1222831 13 19983 1231320 1.60 1251303 14 20493 1266157 1.59 1286650 15 18834 1302540 1.43 1321374 16 17954 1335378 1.33 1353332 17 19380 1349509 1.42 1368889 18 17735 1399664 1.25 1417399 19 17936 1434643 1.23 1452579 20 19965 1482604 1.33 1502569 21 17702 1484270 1.18 1501972 22 18808 1491024 1.25 1509832 23 19970 1493115 1.32 1513085 24 17929 1497116 1.18 1515045 25 18460 1504936 1.21 1523396 26 19983 1518971 1.30 1538954 27 18237 1527082 1.18 1545319 28 18256 1529424 1.18 1547680 29 20058 1523865 1.30 1543923 30 17930 1510819 1.17 1528749 31 17915 1490938 1.19 1508853 32 18946 1498628 1.25 1517574 33 17825 1497196 1.18 1515021 34 19176 1507961 1.26 1527137 35 19565 1494239 1.29 1513804 36 17805 1508181 1.17 1525986 37 17605 1502476 1.16 1520081 38 19810 1506227 1.30 1526037 39 17698 1496398 1.17 1514096 40 18214 1500199 1.20 1518413 41 19919 1508673 1.30 1528592 42 18442 1516370 1.20 1534812 43 19204 1499921 1.26 1519125 44 19598 1510297 1.28 1529895 45 18432 1502295 1.21 1520727 46 18015 1508873 1.18 1526888 47 19303 1503640 1.27 1522943 48 17372 1505918 1.14 1523290 49 17631 1489637 1.17 1507268 50 18936 1489014 1.26 1507950 51 17435 1478778 1.17 1496213 52 18411 1473325 1.23 1491736 53 19204 1467011 1.29 1486215 54 17748 1471909 1.19 1489657 55 18325 1466740 1.23 1485065 56 19337 1465563 1.30 1484900 57 17604 1484259 1.17 1501863 58 19800 1471187 1.33 1490987 59 19623 1483897 1.31 1503520 60 17671 1466320 1.19 1483991 61 18443 1459429 1.25 1477872 62 19099 1450790 1.30 1469889 63 17588 1440033 1.21 1457621 64 18811 1432978 1.30 1451789 65 18816 1431795 1.30 1450611 66 17538 1427234 1.21 1444772 67 17675 1418758 1.23 1436433 68 18407 1415109 1.28 1433516 69 17353 1410902 1.21 1428255 70 17446 1400531 1.23 1417977 71 18518 1397064 1.31 1415582 72 17274 1396132 1.22 1413406 73 18347 1380405 1.31 1398752 74 18582 1380352 1.33 1398934 75 17116 1370775 1.23 1387891 76 17160 1368409 1.24 1385569 77 18249 1357307 1.33 1375556 78 16174 1349931 1.18 1366105 79 16664 1343408 1.23 1360072 80 17714 1336147 1.31 1353861 81 16455 1320637 1.23 1337092 82 17158 1311695 1.29 1328853 83 17584 1313955 1.32 1331539 84 16746 1298999 1.27 1315745 85 16027 1286779 1.23 1302806 86 17166 1276919 1.33 1294085 87 15742 1271229 1.22 1286971 88 15671 1265001 1.22 1280672 89 16980 1255793 1.33 1272773 90 15726 1252135 1.24 1267861 91 15995 1239942 1.27 1255937 92 16608 1238242 1.32 1254850 93 15657 1226616 1.26 1242273 94 15817 1218683 1.28 1234500 95 16911 1206933 1.38 1223844 96 15541 1184808 1.29 1200349 97 15199 1156289 1.30 1171488 98 15487 1077918 1.42 1093405 99 9832 749854 1.29 759686 100 10603 671557 1.55 682160 101 15028 1088478 1.36 1103506 CpG context (R2) ================ position count methylated count unmethylated % methylation coverage 1 156570 243419 39.14 399989 2 138471 220540 38.57 359011 3 150282 247278 37.80 397560 4 147044 281371 34.32 428415 5 60678 352975 14.67 413653 6 34717 190064 15.44 224781 7 31591 199708 13.66 231299 8 33737 189207 15.13 222944 9 29816 168394 15.04 198210 10 33371 184789 15.30 218160 11 35262 179662 16.41 214924 12 35191 173137 16.89 208328 13 35390 170969 17.15 206359 14 37759 174210 17.81 211969 15 36862 161727 18.56 198589 16 35303 157207 18.34 192510 17 41367 170071 19.56 211438 18 40615 164525 19.80 205140 19 39105 158501 19.79 197606 20 37000 155526 19.22 192526 21 38622 154761 19.97 193383 22 37682 155826 19.47 193508 23 35717 150137 19.22 185854 24 35066 143628 19.62 178694 25 38036 150631 20.16 188667 26 35059 144706 19.50 179765 27 37530 145834 20.47 183364 28 35265 141518 19.95 176783 29 36254 145920 19.90 182174 30 35632 136979 20.64 172611 31 33649 137995 19.60 171644 32 32725 131772 19.89 164497 33 35881 133981 21.12 169862 34 34870 138245 20.14 173115 35 40829 146341 21.81 187170 36 35403 133109 21.01 168512 37 35774 135302 20.91 171076 38 32966 130631 20.15 163597 39 34090 128433 20.98 162523 40 35542 130363 21.42 165905 41 32814 126453 20.60 159267 42 32970 129406 20.30 162376 43 33273 127430 20.70 160703 44 31150 123229 20.18 154379 45 36332 130639 21.76 166971 46 30917 117268 20.86 148185 47 31408 118153 21.00 149561 48 31036 116997 20.97 148033 49 29984 119131 20.11 149115 50 28867 112624 20.40 141491 51 29018 110514 20.80 139532 52 29240 113462 20.49 142702 53 29536 110152 21.14 139688 54 28738 109884 20.73 138622 55 29046 108919 21.05 137965 56 27023 107042 20.16 134065 57 27893 106219 20.80 134112 58 27418 105647 20.60 133065 59 26459 100357 20.86 126816 60 27316 101942 21.13 129258 61 24744 98104 20.14 122848 62 24726 97120 20.29 121846 63 26098 96287 21.32 122385 64 24983 95036 20.82 120019 65 24428 90353 21.28 114781 66 25248 93763 21.21 119011 67 24068 94694 20.27 118762 68 24947 96230 20.59 121177 69 23230 89447 20.62 112677 70 22880 89960 20.28 112840 71 23352 85727 21.41 109079 72 22283 84214 20.92 106497 73 22437 86215 20.65 108652 74 20921 83679 20.00 104600 75 21225 82997 20.37 104222 76 21276 81390 20.72 102666 77 21097 80705 20.72 101802 78 21026 81514 20.51 102540 79 20191 79926 20.17 100117 80 19801 77276 20.40 97077 81 19629 76786 20.36 96415 82 19782 76766 20.49 96548 83 19809 74478 21.01 94287 84 20873 79375 20.82 100248 85 19108 74215 20.48 93323 86 18558 73169 20.23 91727 87 18512 71635 20.54 90147 88 18681 71383 20.74 90064 89 19257 71722 21.17 90979 90 18706 71454 20.75 90160 91 18128 69690 20.64 87818 92 17541 68574 20.37 86115 93 17803 68587 20.61 86390 94 17921 67635 20.95 85556 95 17846 67371 20.94 85217 96 17674 67308 20.80 84982 97 18243 68999 20.91 87242 98 16642 61795 21.22 78437 99 14388 0 100.00 14388 CHG context (R2) ================ position count methylated count unmethylated % methylation coverage 1 56094 298803 15.81 354897 2 59184 309719 16.04 368903 3 56264 316849 15.08 373113 4 62339 331795 15.82 394134 5 4803 605334 0.79 610137 6 3596 715887 0.50 719483 7 2304 392086 0.58 394390 8 2365 417242 0.56 419607 9 1993 357300 0.55 359293 10 2028 342361 0.59 344389 11 2719 429837 0.63 432556 12 2262 359660 0.62 361922 13 2223 356892 0.62 359115 14 2321 351858 0.66 354179 15 2260 334100 0.67 336360 16 1935 314830 0.61 316765 17 2322 335920 0.69 338242 18 2332 301404 0.77 303736 19 2142 296389 0.72 298531 20 2119 295922 0.71 298041 21 2478 286369 0.86 288847 22 2304 306055 0.75 308359 23 2239 302109 0.74 304348 24 2114 278728 0.75 280842 25 2182 283534 0.76 285716 26 2236 294464 0.75 296700 27 2111 275259 0.76 277370 28 1998 264340 0.75 266338 29 2177 280542 0.77 282719 30 2201 275486 0.79 277687 31 2163 263907 0.81 266070 32 2084 269777 0.77 271861 33 2359 302487 0.77 304846 34 2081 264612 0.78 266693 35 2174 269491 0.80 271665 36 2125 266975 0.79 269100 37 1992 249529 0.79 251521 38 2098 258584 0.80 260682 39 2121 248375 0.85 250496 40 2083 243318 0.85 245401 41 2107 239433 0.87 241540 42 2151 226265 0.94 228416 43 2067 232570 0.88 234637 44 2042 235518 0.86 237560 45 1983 218996 0.90 220979 46 1876 221589 0.84 223465 47 2015 226390 0.88 228405 48 1921 218320 0.87 220241 49 1961 223280 0.87 225241 50 2065 219113 0.93 221178 51 1880 204405 0.91 206285 52 2106 203032 1.03 205138 53 2456 225326 1.08 227782 54 1959 206782 0.94 208741 55 1985 204776 0.96 206761 56 1895 205795 0.91 207690 57 2017 195753 1.02 197770 58 1748 193781 0.89 195529 59 1703 198754 0.85 200457 60 1574 191252 0.82 192826 61 1350 190897 0.70 192247 62 1454 194193 0.74 195647 63 1451 195216 0.74 196667 64 1257 181548 0.69 182805 65 1369 186763 0.73 188132 66 1193 174569 0.68 175762 67 1360 184063 0.73 185423 68 1256 181202 0.69 182458 69 1283 179571 0.71 180854 70 1220 178331 0.68 179551 71 1229 180709 0.68 181938 72 1184 169057 0.70 170241 73 1161 167259 0.69 168420 74 1209 173220 0.69 174429 75 1169 167356 0.69 168525 76 1030 160458 0.64 161488 77 1141 166448 0.68 167589 78 1110 158760 0.69 159870 79 1130 159185 0.70 160315 80 1104 155652 0.70 156756 81 1084 149810 0.72 150894 82 1020 149428 0.68 150448 83 1068 150701 0.70 151769 84 1000 145498 0.68 146498 85 1101 156138 0.70 157239 86 1069 145111 0.73 146180 87 1059 144120 0.73 145179 88 1018 139132 0.73 140150 89 1113 145904 0.76 147017 90 1058 141623 0.74 142681 91 1011 143507 0.70 144518 92 995 139111 0.71 140106 93 981 134090 0.73 135071 94 956 132181 0.72 133137 95 1011 136146 0.74 137157 96 1025 129685 0.78 130710 97 962 128118 0.75 129080 98 791 124097 0.63 124888 99 659 0 100.00 659 CHH context (R2) ================ position count methylated count unmethylated % methylation coverage 1 83907 425349 16.48 509256 2 69301 355488 16.31 424789 3 69804 365660 16.03 435464 4 70404 357505 16.45 427909 5 9784 675922 1.43 685706 6 10113 936242 1.07 946355 7 11107 1243952 0.88 1255059 8 10958 1234224 0.88 1245182 9 11537 1158564 0.99 1170101 10 11003 1191225 0.92 1202228 11 11125 1169056 0.94 1180181 12 11091 1089740 1.01 1100831 13 10542 1125983 0.93 1136525 14 10970 1137310 0.96 1148280 15 10816 1144944 0.94 1155760 16 9926 1093779 0.90 1103705 17 10758 1097747 0.97 1108505 18 10567 1094598 0.96 1105165 19 9600 1031870 0.92 1041470 20 10624 1072657 0.98 1083281 21 10158 1025164 0.98 1035322 22 10200 1000657 1.01 1010857 23 9842 982560 0.99 992402 24 9496 947546 0.99 957042 25 10128 949130 1.06 959258 26 9539 943497 1.00 953036 27 10397 989124 1.04 999521 28 9515 955757 0.99 965272 29 9687 938742 1.02 948429 30 9935 917907 1.07 927842 31 9292 903847 1.02 913139 32 9124 885721 1.02 894845 33 9740 871321 1.11 881061 34 9080 866799 1.04 875879 35 9787 892159 1.09 901946 36 9151 881428 1.03 890579 37 8933 870673 1.02 879606 38 9392 897829 1.04 907221 39 9304 841437 1.09 850741 40 8966 870029 1.02 878995 41 9042 832567 1.07 841609 42 9235 841391 1.09 850626 43 9008 809201 1.10 818209 44 8354 806168 1.03 814522 45 8965 806361 1.10 815326 46 8498 813952 1.03 822450 47 8280 801093 1.02 809373 48 8563 784695 1.08 793258 49 8162 788047 1.03 796209 50 8198 778427 1.04 786625 51 8401 763920 1.09 772321 52 7689 730357 1.04 738046 53 7724 732019 1.04 739743 54 7641 715482 1.06 723123 55 7515 729177 1.02 736692 56 7384 712687 1.03 720071 57 7351 724842 1.00 732193 58 7017 705915 0.98 712932 59 7095 686032 1.02 693127 60 6934 698699 0.98 705633 61 6650 673044 0.98 679694 62 6656 669074 0.99 675730 63 6380 665725 0.95 672105 64 6340 652639 0.96 658979 65 6070 655785 0.92 661855 66 6261 638383 0.97 644644 67 5940 636122 0.93 642062 68 6326 652416 0.96 658742 69 6344 633528 0.99 639872 70 5876 619105 0.94 624981 71 6048 614434 0.97 620482 72 6043 606828 0.99 612871 73 5939 602589 0.98 608528 74 5743 601432 0.95 607175 75 5647 598562 0.93 604209 76 5432 580183 0.93 585615 77 5691 575763 0.98 581454 78 5727 576748 0.98 582475 79 5625 582028 0.96 587653 80 5616 566338 0.98 571954 81 5732 562635 1.01 568367 82 5535 556706 0.98 562241 83 5131 552613 0.92 557744 84 5553 549028 1.00 554581 85 5170 541327 0.95 546497 86 5029 538046 0.93 543075 87 5186 529686 0.97 534872 88 4919 518395 0.94 523314 89 4913 515100 0.94 520013 90 5076 514484 0.98 519560 91 4926 511349 0.95 516275 92 4721 503039 0.93 507760 93 4718 499428 0.94 504146 94 4520 491506 0.91 496026 95 4676 484649 0.96 489325 96 4526 478963 0.94 483489 97 4279 473164 0.90 477443 98 3797 450436 0.84 454233 99 2695 0 100.00 2695