CpG context (R1) ================ position count methylated count unmethylated % methylation coverage 1 176849 261881 40.31 438730 2 172888 295366 36.92 468254 3 169044 272586 38.28 441630 4 181287 229367 44.15 410654 5 176654 200096 46.89 376750 6 181157 167130 52.01 348287 7 197204 165187 54.42 362391 8 94850 192390 33.02 287240 9 84831 179355 32.11 264186 10 83331 176142 32.12 259473 11 86632 182262 32.22 268894 12 85078 184111 31.61 269189 13 83239 187243 30.77 270482 14 79337 190522 29.40 269859 15 77062 191078 28.74 268140 16 71653 190365 27.35 262018 17 68540 186987 26.82 255527 18 69960 191538 26.75 261498 19 68554 191255 26.39 259809 20 68286 193432 26.09 261718 21 69040 195134 26.13 264174 22 67201 193106 25.82 260307 23 67093 192232 25.87 259325 24 66459 191934 25.72 258393 25 65542 191346 25.51 256888 26 66773 189393 26.07 256166 27 66360 193582 25.53 259942 28 67912 193979 25.93 261891 29 65858 192846 25.46 258704 30 65076 194533 25.07 259609 31 66345 191102 25.77 257447 32 64910 188164 25.65 253074 33 65922 191874 25.57 257796 34 66863 189890 26.04 256753 35 65561 189542 25.70 255103 36 64827 194116 25.04 258943 37 63870 189475 25.21 253345 38 62955 187829 25.10 250784 39 64961 190141 25.46 255102 40 63924 187913 25.38 251837 41 63839 187656 25.38 251495 42 65096 190875 25.43 255971 43 64059 188957 25.32 253016 44 63187 187842 25.17 251029 45 64309 188624 25.43 252933 46 64435 189797 25.34 254232 47 63373 186310 25.38 249683 48 63090 187503 25.18 250593 49 65661 187529 25.93 253190 50 63637 189010 25.19 252647 51 63875 187399 25.42 251274 52 64722 191574 25.25 256296 53 62715 185047 25.31 247762 54 61874 185210 25.04 247084 55 62029 181411 25.48 243440 56 62061 181788 25.45 243849 57 62962 182916 25.61 245878 58 64148 183504 25.90 247652 59 64836 181173 26.36 246009 60 63943 182348 25.96 246291 61 64704 180282 26.41 244986 62 62602 180421 25.76 243023 63 62287 179429 25.77 241716 64 61133 177437 25.62 238570 65 61749 175925 25.98 237674 66 62793 177257 26.16 240050 67 61563 173006 26.25 234569 68 60646 173492 25.90 234138 69 60143 171386 25.98 231529 70 59564 171397 25.79 230961 71 58083 166785 25.83 224868 72 57026 166694 25.49 223720 73 57073 164609 25.75 221682 74 56372 163179 25.68 219551 75 54866 164156 25.05 219022 76 54903 162388 25.27 217291 77 55607 158872 25.93 214479 78 54879 161396 25.37 216275 79 53967 158177 25.44 212144 80 53238 157017 25.32 210255 81 52863 156147 25.29 209010 82 51328 153981 25.00 205309 83 51979 154526 25.17 206505 84 51564 153295 25.17 204859 85 50718 151096 25.13 201814 86 49492 149301 24.90 198793 87 48355 147857 24.64 196212 88 48685 147699 24.79 196384 89 47886 144699 24.86 192585 90 47598 144312 24.80 191910 91 47129 142370 24.87 189499 92 46012 140714 24.64 186726 93 46191 140776 24.71 186967 94 45564 139540 24.62 185104 95 44973 137185 24.69 182158 96 45060 138289 24.58 183349 97 43703 132833 24.76 176536 98 41033 125748 24.60 166781 99 32483 99075 24.69 131558 100 42545 125721 25.28 168266 101 40415 126163 24.26 166578 CHG context (R1) ================ position count methylated count unmethylated % methylation coverage 1 231139 368133 38.57 599272 2 134926 363164 27.09 498090 3 59641 353263 14.44 412904 4 35050 345488 9.21 380538 5 24132 312554 7.17 336686 6 20620 294512 6.54 315132 7 16137 372880 4.15 389017 8 7370 405863 1.78 413233 9 6104 386743 1.55 392847 10 6116 374594 1.61 380710 11 6297 380515 1.63 386812 12 6045 379186 1.57 385231 13 5803 367576 1.55 373379 14 5414 368891 1.45 374305 15 5526 380000 1.43 385526 16 4700 379553 1.22 384253 17 5334 376112 1.40 381446 18 4779 375033 1.26 379812 19 4240 377053 1.11 381293 20 4435 396561 1.11 400996 21 4392 399607 1.09 403999 22 4608 394370 1.15 398978 23 4735 399818 1.17 404553 24 4509 404071 1.10 408580 25 4574 393539 1.15 398113 26 5451 394551 1.36 400002 27 4474 402204 1.10 406678 28 4634 401291 1.14 405925 29 5071 405647 1.23 410718 30 4417 407260 1.07 411677 31 4236 396743 1.06 400979 32 4400 403306 1.08 407706 33 4420 403572 1.08 407992 34 4455 396465 1.11 400920 35 4983 398179 1.24 403162 36 4577 401046 1.13 405623 37 4497 389624 1.14 394121 38 4844 395856 1.21 400700 39 4427 393929 1.11 398356 40 4348 393306 1.09 397654 41 4374 392892 1.10 397266 42 4369 396746 1.09 401115 43 4193 387949 1.07 392142 44 4373 394453 1.10 398826 45 4422 392852 1.11 397274 46 4335 389861 1.10 394196 47 4621 391267 1.17 395888 48 4420 399476 1.09 403896 49 4399 389214 1.12 393613 50 4704 387197 1.20 391901 51 4486 393500 1.13 397986 52 4569 390961 1.16 395530 53 4561 386213 1.17 390774 54 4741 394373 1.19 399114 55 4669 386867 1.19 391536 56 4798 390601 1.21 395399 57 4948 390647 1.25 395595 58 5131 385037 1.32 390168 59 5210 387513 1.33 392723 60 5184 390422 1.31 395606 61 5165 383217 1.33 388382 62 5378 382311 1.39 387689 63 5359 378285 1.40 383644 64 5454 375229 1.43 380683 65 6075 374948 1.59 381023 66 5445 367582 1.46 373027 67 5470 360266 1.50 365736 68 5698 362076 1.55 367774 69 5280 361732 1.44 367012 70 5108 352638 1.43 357746 71 5119 353150 1.43 358269 72 5086 352830 1.42 357916 73 5147 347801 1.46 352948 74 5326 346574 1.51 351900 75 4846 344403 1.39 349249 76 4790 335913 1.41 340703 77 5410 336498 1.58 341908 78 4966 331018 1.48 335984 79 5008 323868 1.52 328876 80 5037 324460 1.53 329497 81 4798 321424 1.47 326222 82 4700 314866 1.47 319566 83 5017 318857 1.55 323874 84 4958 318048 1.53 323006 85 4903 311656 1.55 316559 86 4982 311391 1.57 316373 87 4812 313110 1.51 317922 88 4874 304760 1.57 309634 89 4879 302004 1.59 306883 90 4637 302067 1.51 306704 91 4826 297500 1.60 302326 92 4999 296569 1.66 301568 93 5074 294156 1.70 299230 94 4798 288501 1.64 293299 95 4986 285741 1.72 290727 96 5012 283696 1.74 288708 97 4892 259331 1.85 264223 98 4494 240357 1.84 244851 99 2841 155034 1.80 157875 100 3448 156215 2.16 159663 101 6595 260221 2.47 266816 CHH context (R1) ================ position count methylated count unmethylated % methylation coverage 1 294946 495836 37.30 790782 2 163178 543499 23.09 706677 3 93350 612628 13.22 705978 4 85443 640611 11.77 726054 5 80160 758953 9.55 839113 6 65880 825346 7.39 891226 7 53470 1042859 4.88 1096329 8 37512 1130670 3.21 1168182 9 29262 1037902 2.74 1067164 10 28832 1004413 2.79 1033245 11 35434 1009739 3.39 1045173 12 30423 1018412 2.90 1048835 13 33751 1033938 3.16 1067689 14 36009 1063672 3.27 1099681 15 31520 1092857 2.80 1124377 16 30063 1108068 2.64 1138131 17 34077 1117493 2.96 1151570 18 29280 1156710 2.47 1185990 19 29874 1180576 2.47 1210450 20 34162 1218389 2.73 1252551 21 29767 1219556 2.38 1249323 22 32064 1222493 2.56 1254557 23 34783 1219015 2.77 1253798 24 29970 1218474 2.40 1248444 25 31959 1221075 2.55 1253034 26 34755 1233584 2.74 1268339 27 30332 1239190 2.39 1269522 28 29665 1246910 2.32 1276575 29 34553 1240276 2.71 1274829 30 29723 1231194 2.36 1260917 31 30404 1219420 2.43 1249824 32 32494 1219189 2.60 1251683 33 29761 1224612 2.37 1254373 34 33369 1230932 2.64 1264301 35 34470 1217570 2.75 1252040 36 29760 1229853 2.36 1259613 37 29294 1222213 2.34 1251507 38 34566 1228193 2.74 1262759 39 29742 1219404 2.38 1249146 40 30289 1216506 2.43 1246795 41 34066 1221005 2.71 1255071 42 30503 1226540 2.43 1257043 43 32376 1215490 2.59 1247866 44 33416 1224047 2.66 1257463 45 31188 1209784 2.51 1240972 46 30664 1215971 2.46 1246635 47 33033 1213109 2.65 1246142 48 28585 1212756 2.30 1241341 49 29532 1201928 2.40 1231460 50 32754 1198732 2.66 1231486 51 28652 1187417 2.36 1216069 52 30194 1185441 2.48 1215635 53 32569 1176561 2.69 1209130 54 28798 1178609 2.39 1207407 55 29943 1169012 2.50 1198955 56 32523 1168652 2.71 1201175 57 28752 1172751 2.39 1201503 58 29503 1171367 2.46 1200870 59 33035 1170732 2.74 1203767 60 28288 1157517 2.39 1185805 61 30311 1146470 2.58 1176781 62 31952 1134600 2.74 1166552 63 28397 1124316 2.46 1152713 64 29988 1116728 2.62 1146716 65 31216 1109261 2.74 1140477 66 27597 1102225 2.44 1129822 67 27826 1092512 2.48 1120338 68 29961 1084440 2.69 1114401 69 27133 1079507 2.45 1106640 70 27300 1069233 2.49 1096533 71 29676 1065057 2.71 1094733 72 26943 1061119 2.48 1088062 73 28742 1045066 2.68 1073808 74 29859 1040913 2.79 1070772 75 26515 1030217 2.51 1056732 76 26690 1024189 2.54 1050879 77 30083 1014308 2.88 1044391 78 25194 1007619 2.44 1032813 79 26258 1000596 2.56 1026854 80 28787 990698 2.82 1019485 81 26385 977069 2.63 1003454 82 26966 967526 2.71 994492 83 28653 966123 2.88 994776 84 25981 953444 2.65 979425 85 25013 941060 2.59 966073 86 27120 931094 2.83 958214 87 23977 922401 2.53 946378 88 24030 916311 2.56 940341 89 26983 904533 2.90 931516 90 23868 901863 2.58 925731 91 24478 889679 2.68 914157 92 25804 886305 2.83 912109 93 23582 877928 2.62 901510 94 23786 866844 2.67 890630 95 25971 854566 2.95 880537 96 22721 840297 2.63 863018 97 22798 818980 2.71 841778 98 24040 763034 3.05 787074 99 13941 532520 2.55 546461 100 15226 472097 3.12 487323 101 23549 772603 2.96 796152 CpG context (R2) ================ position count methylated count unmethylated % methylation coverage 1 160744 183803 46.65 344547 2 138208 157683 46.71 295891 3 146174 177866 45.11 324040 4 133350 195827 40.51 329177 5 58067 252640 18.69 310707 6 35851 137943 20.63 173794 7 30969 146653 17.44 177622 8 32835 138029 19.22 170864 9 28293 118445 19.28 146738 10 30421 130735 18.88 161156 11 32828 128944 20.29 161772 12 32125 124829 20.47 156954 13 33092 120729 21.51 153821 14 34091 124181 21.54 158272 15 33599 113770 22.80 147369 16 31353 108724 22.38 140077 17 37937 117556 24.40 155493 18 36042 112995 24.18 149037 19 34732 111675 23.72 146407 20 32054 107056 23.04 139110 21 33392 103542 24.39 136934 22 33510 109205 23.48 142715 23 31612 103663 23.37 135275 24 29832 101057 22.79 130889 25 33074 104401 24.06 137475 26 30473 99568 23.43 130041 27 32457 100785 24.36 133242 28 29938 94739 24.01 124677 29 31058 99635 23.76 130693 30 29790 93804 24.10 123594 31 28794 96475 22.99 125269 32 28035 90422 23.67 118457 33 31638 91453 25.70 123091 34 30267 95117 24.14 125384 35 36993 101755 26.66 138748 36 29685 90682 24.66 120367 37 31148 94536 24.78 125684 38 27834 88234 23.98 116068 39 29044 87562 24.91 116606 40 31650 87434 26.58 119084 41 27643 85381 24.46 113024 42 27918 88414 24.00 116332 43 27937 85324 24.67 113261 44 25940 82585 23.90 108525 45 31465 90405 25.82 121870 46 25428 77819 24.63 103247 47 25916 80255 24.41 106171 48 25965 80204 24.46 106169 49 24798 82776 23.05 107574 50 23688 75433 23.90 99121 51 23694 73924 24.27 97618 52 23691 75255 23.94 98946 53 24114 73639 24.67 97753 54 23625 73645 24.29 97270 55 23503 70713 24.95 94216 56 22150 69204 24.25 91354 57 22912 70460 24.54 93372 58 22088 70152 23.95 92240 59 20682 64500 24.28 85182 60 21500 65301 24.77 86801 61 19388 64186 23.20 83574 62 19790 61662 24.30 81452 63 20925 60901 25.57 81826 64 19538 61327 24.16 80865 65 19389 57439 25.24 76828 66 20440 60740 25.18 81180 67 18562 61506 23.18 80068 68 21021 62820 25.07 83841 69 18830 58478 24.36 77308 70 18025 58158 23.66 76183 71 18677 53241 25.97 71918 72 17571 53071 24.87 70642 73 17422 53782 24.47 71204 74 16181 52348 23.61 68529 75 16694 52804 24.02 69498 76 16607 50581 24.72 67188 77 16267 51194 24.11 67461 78 16177 51349 23.96 67526 79 15472 49186 23.93 64658 80 15321 47980 24.20 63301 81 14982 48960 23.43 63942 82 15360 48177 24.17 63537 83 15640 45686 25.50 61326 84 16925 50788 25.00 67713 85 14433 47570 23.28 62003 86 14328 46287 23.64 60615 87 14374 45236 24.11 59610 88 14215 44469 24.22 58684 89 15120 46077 24.71 61197 90 15013 45307 24.89 60320 91 13765 43528 24.03 57293 92 13422 43042 23.77 56464 93 13784 42959 24.29 56743 94 14273 42806 25.01 57079 95 13818 41598 24.94 55416 96 13206 41754 24.03 54960 97 14632 44453 24.76 59085 98 13044 39526 24.81 52570 99 11826 0 100.00 11826 CHG context (R2) ================ position count methylated count unmethylated % methylation coverage 1 45805 220159 17.22 265964 2 45101 224347 16.74 269448 3 42529 230360 15.58 272889 4 46502 246226 15.89 292728 5 5798 447868 1.28 453666 6 4242 546838 0.77 551080 7 2709 307266 0.87 309975 8 2638 330214 0.79 332852 9 2382 272363 0.87 274745 10 2451 260141 0.93 262592 11 3517 355466 0.98 358983 12 2596 278167 0.92 280763 13 2560 277102 0.92 279662 14 2664 265025 1.00 267689 15 2602 259056 0.99 261658 16 2310 240255 0.95 242565 17 2752 257438 1.06 260190 18 2908 225586 1.27 228494 19 2581 226993 1.12 229574 20 2461 224546 1.08 227007 21 2933 211691 1.37 214624 22 2788 234278 1.18 237066 23 2579 232950 1.09 235529 24 2325 207104 1.11 209429 25 2493 211826 1.16 214319 26 2668 222820 1.18 225488 27 2510 208058 1.19 210568 28 2492 200145 1.23 202637 29 2635 214586 1.21 217221 30 2604 203751 1.26 206355 31 2409 196160 1.21 198569 32 2362 199891 1.17 202253 33 2825 235900 1.18 238725 34 2363 193936 1.20 196299 35 2579 199834 1.27 202413 36 2491 198530 1.24 201021 37 2329 184294 1.25 186623 38 2618 198515 1.30 201133 39 2597 183157 1.40 185754 40 2444 180750 1.33 183194 41 2561 174691 1.44 177252 42 2585 163674 1.55 166259 43 2883 172535 1.64 175418 44 2385 168820 1.39 171205 45 2220 155287 1.41 157507 46 2386 155369 1.51 157755 47 2460 160068 1.51 162528 48 2389 152893 1.54 155282 49 2489 160593 1.53 163082 50 2612 153396 1.67 156008 51 2300 144015 1.57 146315 52 2383 141886 1.65 144269 53 2718 157812 1.69 160530 54 2270 142841 1.56 145111 55 2385 144557 1.62 146942 56 2100 141449 1.46 143549 57 2361 135326 1.71 137687 58 2011 136163 1.46 138174 59 1734 136991 1.25 138725 60 1563 130904 1.18 132467 61 1510 129866 1.15 131376 62 1362 135303 1.00 136665 63 1406 136230 1.02 137636 64 1242 122201 1.01 123443 65 1354 130806 1.02 132160 66 1259 118912 1.05 120171 67 1402 129678 1.07 131080 68 1330 125670 1.05 127000 69 1298 121610 1.06 122908 70 1224 121408 1.00 122632 71 1295 124492 1.03 125787 72 1228 113369 1.07 114597 73 1136 113107 0.99 114243 74 1169 116715 0.99 117884 75 1108 111084 0.99 112192 76 1080 108249 0.99 109329 77 1194 115634 1.02 116828 78 1146 109470 1.04 110616 79 1142 108984 1.04 110126 80 1025 105186 0.97 106211 81 1080 100887 1.06 101967 82 1056 99974 1.05 101030 83 1164 102481 1.12 103645 84 993 98109 1.00 99102 85 1116 109387 1.01 110503 86 1041 98958 1.04 99999 87 1103 98385 1.11 99488 88 1034 93864 1.09 94898 89 1171 99569 1.16 100740 90 1031 97405 1.05 98436 91 1097 100828 1.08 101925 92 1037 95868 1.07 96905 93 1033 91809 1.11 92842 94 992 90160 1.09 91152 95 1035 92254 1.11 93289 96 1059 87641 1.19 88700 97 1014 87630 1.14 88644 98 839 86512 0.96 87351 99 702 0 100.00 702 CHH context (R2) ================ position count methylated count unmethylated % methylation coverage 1 71720 292644 19.68 364364 2 60226 242581 19.89 302807 3 61146 244256 20.02 305402 4 61444 237637 20.54 299081 5 17603 481464 3.53 499067 6 17478 660135 2.58 677613 7 18705 888020 2.06 906725 8 17077 875742 1.91 892819 9 19707 825337 2.33 845044 10 17793 844704 2.06 862497 11 17678 829797 2.09 847475 12 16430 775958 2.07 792388 13 16199 800599 1.98 816798 14 17175 803284 2.09 820459 15 16674 828609 1.97 845283 16 14963 794190 1.85 809153 17 16550 796165 2.04 812715 18 15848 792013 1.96 807861 19 14621 732562 1.96 747183 20 16564 780119 2.08 796683 21 15999 725145 2.16 741144 22 15795 707510 2.18 723305 23 15671 692091 2.21 707762 24 14616 663681 2.15 678297 25 15723 659956 2.33 675679 26 14987 657171 2.23 672158 27 15769 700095 2.20 715864 28 14892 672025 2.17 686917 29 15114 659548 2.24 674662 30 15544 634522 2.39 650066 31 14647 618360 2.31 633007 32 14412 598599 2.35 613011 33 15417 592988 2.53 608405 34 14642 590953 2.42 605595 35 15641 612952 2.49 628593 36 14394 605978 2.32 620372 37 14216 593651 2.34 607867 38 15202 618266 2.40 633468 39 14618 569112 2.50 583730 40 14432 594713 2.37 609145 41 14565 559870 2.54 574435 42 14500 570876 2.48 585376 43 14304 540061 2.58 554365 44 13250 539700 2.40 552950 45 14144 536900 2.57 551044 46 13448 540096 2.43 553544 47 12836 527078 2.38 539914 48 13348 513015 2.54 526363 49 12747 522149 2.38 534896 50 12762 509178 2.45 521940 51 12907 495316 2.54 508223 52 11885 469445 2.47 481330 53 12206 473240 2.51 485446 54 11461 460998 2.43 472459 55 11229 474421 2.31 485650 56 11035 459737 2.34 470772 57 11002 469368 2.29 480370 58 10222 453382 2.20 463604 59 10485 435178 2.35 445663 60 9966 446915 2.18 456881 61 10202 424060 2.35 434262 62 9719 418714 2.27 428433 63 9511 422866 2.20 432377 64 9448 408499 2.26 417947 65 9328 416406 2.19 425734 66 9164 401732 2.23 410896 67 8788 401167 2.14 409955 68 8950 414172 2.12 423122 69 9112 403518 2.21 412630 70 8598 388708 2.16 397306 71 8636 382541 2.21 391177 72 9068 382747 2.31 391815 73 8390 376139 2.18 384529 74 8202 375737 2.14 383939 75 8439 375503 2.20 383942 76 7814 360751 2.12 368565 77 8487 360094 2.30 368581 78 8271 362554 2.23 370825 79 8029 368495 2.13 376524 80 8202 355442 2.26 363644 81 8220 356321 2.25 364541 82 8000 348857 2.24 356857 83 7729 347540 2.18 355269 84 8026 344812 2.27 352838 85 7660 337699 2.22 345359 86 7642 337566 2.21 345208 87 7449 333797 2.18 341246 88 7006 322074 2.13 329080 89 7280 320631 2.22 327911 90 7205 321332 2.19 328537 91 6847 318257 2.11 325104 92 6809 314823 2.12 321632 93 6829 311298 2.15 318127 94 6454 307710 2.05 314164 95 6841 299107 2.24 305948 96 6441 297400 2.12 303841 97 6055 297832 1.99 303887 98 5772 286677 1.97 292449 99 4102 0 100.00 4102