Ping-pong signatures for 100 pseudo-replicate datasets (1000000 reads each) based on sRNA-ACR-140_preproc.map (7898972 reads) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 ppZScore ppSequences ppReads 1 7344.19900759328 9554.62794889149 10068.2137019766 13929.1721471451 28111.7816134261 19184.0534223279 37880.5573657569 69070.3708793474 111577.50196225 1774209.68973882 119955.257444674 149348.605462194 35739.0662499566 28869.0068374168 29946.6779194349 12772.8549777938 19499.5611150387 13005.3465437595 20964.2882138154 11841.1464918489 8921.39763550138 8632.18183619604 8575.02297713423 6018.69212865567 5655.34771087239 6163.22755153894 2503.19880793506 1612.77237115959 449.728596640694 0 42.4391930773633 53904 260929 2 6953.98524990333 8195.54286648235 10368.6374179578 14722.5046739099 24741.4469310812 21379.2751806204 35938.2176672078 65793.6777852503 121412.093817456 1734396.82766259 115905.041458892 136666.350966767 32257.1123704011 28630.3969381085 28897.312239673 14222.7640884218 20431.0586738769 12948.2934067446 24835.9494499787 12814.955816334 8501.98455129903 7272.20712930143 9423.76602700271 5500.27303022404 7275.84030274431 6116.68074481507 2933.45240362956 1827.0941432882 772.463694317882 0 42.9236184204574 53527 258632 3 8010.8512148919 8761.0529757406 10636.865518486 15410.104006279 24339.6058813997 19919.3043889557 38316.3203524756 52700.1865912985 110531.234045117 1661379.63299767 105274.179503022 130208.863024277 34344.2145003734 26864.0691891325 35667.0603406743 13876.6785536727 19397.4852748473 12855.251577181 29337.5184262903 12978.6242562744 10424.9914251125 8101.51329880555 7941.47605494722 4941.66147447121 7515.97545527719 7896.84072428765 3145.92252393554 1705.95982614089 679.108209906319 0 45.2929254773114 54222 265228 4 7756.0567412197 6841.14175521144 11063.8152660013 14155.7154231063 26511.5981975104 19432.2110287054 34446.9453514187 54023.1581326157 98329.8041694467 1680997.77648587 107127.99968772 135941.94384271 32588.7475646541 28235.706556666 29563.5043296981 13437.075398889 19127.5914491279 12356.0520226719 25846.646276236 12315.9636396528 10543.7346435246 7136.03747241461 9029.26759332536 6309.7854912076 8022.7595969602 6883.50890871308 3473.85337114534 1590.86520607404 669.555092362743 0 45.802295250942 54045 263782 5 8700.5832433407 9990.59744869708 11735.3955777745 14747.9609979703 29988.8714348667 20184.0827136278 38650.5066996122 68321.4726331761 93412.9166036898 1741898.95706128 118126.713781058 127893.383310213 37354.728800066 27204.3430776445 27048.2361737011 14077.0512217035 21783.038722631 13799.9185452184 23832.5734818496 11567.6192905623 10223.0313251468 8720.39215661597 8568.40836356183 5922.20108695852 6542.14281496973 7345.35821136361 2888.16360756435 1457.28476003188 595.651362097537 0 47.647220463601 54080 260509 6 7698.50804742937 9763.61070889731 10450.4546684253 12971.7062234609 29020.6275357917 21005.5177941264 38411.4723573413 67326.1552206093 135268.646909559 1755688.11030097 116682.383732994 137335.146257136 35696.1654611593 29327.4924752441 31029.1416079216 14205.1667511208 20961.529284363 12588.059929803 23841.9867805606 12908.3481854411 9314.985689401 8871.75562247863 9507.60803852785 5237.92032073977 9412.59676990372 6207.89059460511 4643.24261695277 1250.88548806588 710.942052153038 0 41.66307980041 53912 255115 7 7769.97708151681 8957.13752605436 10501.1894183052 12521.0494494395 27220.5708829933 19328.1535177738 35126.5309116405 55086.1051184731 100737.079372672 1788025.76644439 119677.377879112 131009.560833989 36307.9050352357 28635.3814748137 28026.1253997646 14093.2078582312 19691.7070094301 12317.6050145111 24439.4361392638 13414.1855323382 8394.2576992781 7705.8712287597 8003.21735948273 4716.23401684734 6482.3020528398 8043.12707854589 3070.8619184124 1673.35643372055 381.311361632773 0 47.594061786516 53993 260986 8 7272.44115721295 8917.7405885748 10824.3388434751 13726.0528152728 27107.7974316411 22450.9042698541 35545.5198920999 61778.6074271492 109509.043004116 1773925.31381912 123452.544465266 111296.626750059 35243.0664183137 25987.8384093049 30276.7177606876 13563.0644385892 20916.2431211489 12948.0430490259 28152.3554119001 10953.8683862995 9515.1179621246 8156.48981586164 9605.38921720708 6966.53148413471 7381.66699683609 5703.08251859164 2268.95160606239 1740.61625643838 477.814463246953 0 48.4720371806695 53420 259185 9 8713.05796390458 10208.7978468679 10237.5445569317 16034.1661100974 26795.4122216399 21392.9789471386 39649.8203879451 62574.3772169709 122870.116058722 1578974.52754768 109929.024607611 141009.376475609 34975.0934172067 26750.4449570605 29873.3666432723 12975.8331413438 20072.336461934 13532.0433513885 22738.5086035086 12467.0390932347 9354.92944180911 6875.11071469241 11185.3753178716 6910.47278870618 6965.02899684333 6558.5177151331 2941.85579945804 1556.08337229958 755.568586896619 0 39.0870808865478 53667 258290 10 6490.47097130086 7664.5863036786 10298.2000381083 14847.5130593686 26698.0690461453 22029.3353584737 35801.9323458294 63994.2298497224 105452.849532252 1629588.91184397 114601.235475631 123924.346828586 35264.9739219012 30034.0171423675 28130.8009575369 14263.461026472 23176.8891885814 13865.7481527268 26460.9023330251 10893.2406562468 10623.5752015628 8087.1514636124 9987.60117476793 6341.22257227321 7284.32745532793 6016.41350864856 4062.11188425557 1496.59445612309 547.550593572427 0 44.3535388906742 53508 258256 11 7332.33729833661 8295.02444595018 10959.6602384644 14652.2513519702 27839.9167799667 19812.6591413287 37819.0476955745 58941.2435864491 93652.1461643097 1746487.17058068 113715.723094182 136782.613636187 33671.8487953902 27484.3860200643 32878.3832499025 12983.8961509113 20472.5011696776 12402.5895187969 20839.5155634641 12037.52858746 8686.78556419738 8119.67935949078 10293.7145738983 6162.06045527259 6159.19040628457 5648.81295250074 2418.12062095595 1533.13003579469 762.475541584215 0 46.8919449861969 53661 259486 12 8396.70356613958 7924.54747624085 11797.3231718732 14762.0608051752 25043.3008854205 20741.462970005 36848.3733500677 53066.4325321732 103843.584925729 1540351.3626459 102211.429888156 126962.206694076 34746.8153669326 28635.7592268646 32147.1814242737 13529.1271701649 21688.3490952902 12517.686226916 22854.494690277 11405.4650589248 8613.07815163311 8980.35795712323 9490.5680664693 6445.04357464308 8016.43583054789 6219.25602051134 3258.79389961494 1428.01870781109 510.95072059764 0 43.6100062813274 53845 259954 13 7096.69263548661 7701.70904536969 10225.1965464605 14083.5119899883 25088.0061611201 19081.0468389145 36407.5962255805 57215.2192834362 96415.791132948 1681189.63892381 108246.598617524 128035.671546686 33368.3918584315 27192.9909208617 28740.4140551183 13815.8659216382 19742.4967982657 12730.4681977816 24624.1802375523 12616.8135923655 8374.95379265779 7887.11247799671 11946.0196138722 7936.33105502683 9296.21035291559 5589.68484659185 5703.72551863123 1509.66589096459 985.799076941584 0 47.1979684084658 53331 259697 14 6257.72212224538 8812.00892435293 9780.47436400503 14359.9628225581 26714.4371855893 17946.8202497307 36096.5728565336 53572.8004216245 112605.025841849 1692877.34788892 125249.53279424 144075.126863022 33369.3675055879 30267.0091447933 32401.0024263174 13899.531563971 20921.2000282676 14086.5885828638 22851.4834669201 12116.893896083 10007.6642614077 8156.24826910395 8494.87396727906 5706.85830556421 8380.58472352144 6332.77088150612 3277.73421731388 1533.97944431361 547.02687744531 0 41.0398978067003 54257 257223 15 7484.46762194399 9895.30097777506 10319.8632657432 13983.4275140238 27156.6737309093 20062.1722365881 37493.0721299632 63230.3123959871 109128.16407396 1772173.48845505 118958.93723967 126376.905285765 33256.1698561495 26533.3912915398 31147.7117481916 13086.2797662016 17191.7985939674 10952.3312105884 20283.4813440055 10985.5342481646 9270.02155247876 7869.72501652685 10688.2522363767 5929.96041621283 6819.41041676754 6414.90457382266 2758.08682414656 1549.4080187953 552.854976693233 0 46.382839919647 53901 262947 16 8162.0468238829 7948.18494098157 10775.5889590266 14549.9431813118 25651.4851164892 19365.0598067175 36584.0617061876 56578.1056590609 92978.1399756317 1650097.73635843 113816.18013937 130593.839956231 32374.8950093214 29968.9263187061 31687.6476195215 16411.8528670651 18015.2934547776 14108.4152868752 29523.4273454708 13641.9265849553 8548.54196691383 7506.25266925256 10084.294781738 5814.02401286368 8480.01727655655 8128.15302183292 5415.74925346943 1578.27238054069 553.112287108705 0 45.8740230680905 53879 257703 17 7940.81001979251 10632.4723727291 10946.0587575211 13609.4335053574 25475.2900307712 19862.4271058831 38614.7907745294 61505.8901945269 98703.2718431528 1797400.22689009 113782.507942773 128772.79803308 35610.6617329577 31609.1045393894 31447.7231453554 12717.4616921043 21356.160826607 12851.0181657094 24145.2682682852 12209.5050179841 9055.06943220809 6951.83992206038 9200.3631777731 6091.87281829657 8101.62538973782 6474.90851668203 3397.14285187679 1583.94389198884 762.717154831163 0 49.338568440402 53896 259803 18 7401.67935871657 9983.89957736344 12041.8803894781 14919.2159911095 25335.089400596 21640.018675846 38856.9654132851 57706.2213653247 100721.40071014 1708994.88365559 114103.095000397 138064.127791799 33861.1021842828 27612.0472720631 34540.9597249876 14649.6558958005 21176.4527779642 12873.3849562736 26346.2777256179 13341.5360001386 8960.80088762374 8582.28353546255 8735.54440656603 6442.16087154193 6399.9231387679 6345.23656337646 3212.63671969137 1677.54462800461 904.752138869025 0 45.3213711530196 54001 257306 19 7040.38183975278 8729.92514019547 10946.4091739333 15583.7683758554 25777.6210890552 19530.5544134725 37179.1000816547 56911.0289575311 83646.1064552773 1646393.50103067 106805.718338794 134403.55353676 32711.3005934745 28192.1922540575 28510.5339971789 14390.7378533099 21196.847529913 14950.7533534472 23407.763291826 13594.1027152634 9472.87410178938 9519.83799047094 12069.4284061266 6210.76722718207 9847.94830011812 5676.31790708297 4929.1258505539 1687.8522247519 574.45958014293 0 46.9800327409943 53773 256469 20 9147.24773358983 10227.7293321855 10377.4471272527 15399.9502493048 28171.0370662945 19241.496617475 34760.7196027025 50225.3909548592 103214.985058127 1608063.93442791 105439.007083313 138326.937359374 33832.7815054357 28280.3899005591 26785.6233756552 12629.2939929563 18173.8543549642 13454.1708333394 24719.8630403668 11443.5440959719 9067.21139369241 7487.84160536088 8442.58753462113 4782.56737415779 5605.65884449504 5098.13867871925 2299.00296709285 1403.0546199486 744.818103738933 0 43.264637750335 53610 259373 21 7935.20206512213 8503.46095799711 10460.142247627 12746.2588030717 29248.6442556784 18216.6058247807 37279.4002900416 58639.1106382021 102593.710644716 1783267.39310619 120390.462723712 132130.555792766 32739.436125517 25941.7006965757 27380.3728480375 13095.3267017282 20640.4425942612 13361.8760047222 22310.4527111084 12051.8366751838 9707.37559950704 8119.81017723713 8293.73218472029 5514.35999090483 8931.23021140919 5926.23201722074 4001.73362707129 1353.87174992527 481.431965555964 0 46.662295894029 53746 256170 22 6667.98895529864 8307.54240067656 10461.5665514794 12511.3563138257 28972.7417599965 18249.9974582758 34265.4322369361 60043.7777546132 120991.803513619 1662846.47657585 123299.274305312 137916.829925409 35662.0387520637 25663.6609624565 27724.7162414202 15093.3628455785 20551.5967412216 14214.5894623957 26557.908571768 12967.8923143587 10999.5495375726 7314.86239239464 11065.9260180957 6289.05710616852 6186.90516433837 5579.9645492022 2281.70309062161 1747.63331261115 588.954035522359 0 40.3405888089569 53513 259394 23 7239.58053580304 6880.22024199507 10707.9738190347 14325.5516769789 26024.4767987645 17705.333763607 38737.8654270949 60281.9051442751 94356.0458219104 1775514.66764349 117573.101905033 125045.862598964 33080.8560213952 26422.00873475 26812.3982462824 14450.2165143286 18038.6490869013 14466.3593728216 25271.5396524701 11186.3465171427 8548.00168523008 8022.33243647856 9426.89569017492 5431.69438746801 6810.7435000846 7171.0282886919 3639.38564476525 1791.5799721361 443.386619972136 0 48.9680359636134 53741 255250 24 7449.08099774067 9337.28921641058 11827.8355900062 15842.8503735744 26291.933135562 21232.4032761012 36441.8831714751 57223.3528655956 112793.15380143 1694311.04985389 115175.856210623 109264.890895672 35039.458176334 30502.7075212752 25450.5131971703 13346.0063307401 18927.6395506787 13867.8735855479 26335.7840035429 15002.1002565408 8474.90801526162 6455.83156996155 10504.8735422756 6207.11598470478 6010.90734891345 7444.76737888235 2997.46417293274 1255.28046985672 695.809206823182 0 47.8777658255147 53952 263606 25 8500.85583554936 8215.11465507817 11436.1762550244 14939.9343681503 25102.352804559 19845.3019346665 38785.9637426216 54760.4680285466 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12955.6899778527 20804.6059416928 13383.0679875067 23413.3422820922 12475.8926210296 9190.1896209366 7164.21983278065 9910.28015738442 8300.20768201022 7618.21879917525 7815.83475403047 3382.03281446869 1449.69816708434 689.164266496748 0 45.4281581818782 53911 257734 96 7890.18855361294 7947.18046510767 11377.7715711533 13621.6813008992 26201.0357226386 20207.5711315667 35754.5276822802 60391.5036336344 116448.201213455 1724104.83752902 113128.761544295 140205.151879523 38178.5118767464 28646.5969434071 35086.6948177506 13447.4866525508 20181.8758531843 13794.8193544916 24241.3701711597 11780.3200079272 9360.93272551226 7760.14431549052 8378.33457287883 5898.72576708015 6416.84648144756 7506.32619504394 3106.91794562173 1814.39548805072 467.515932281497 0 43.2974078618741 53493 256664 97 9019.68599505142 7938.31862852504 11442.5744897024 13675.5936486343 29060.5594634924 21463.815938087 39220.145052897 55933.5307420031 97556.4650250263 1770302.16742649 118632.485377359 127684.772898856 30931.174610928 27710.3236892997 26133.2970013306 11059.4194495172 19245.9149502489 12447.0218581839 25242.5267133738 14163.1650540785 8921.69406784142 8405.01019929328 8191.39263679604 4852.91640467554 6014.14697951252 7195.79704167336 2709.76161228625 1294.29447161103 743.398284648467 0 48.2379973562657 53321 255757 98 8184.1074498695 8012.83101639836 11397.803236937 13264.1757523695 24939.5065057292 19756.888120296 37904.9948336298 51833.3901720517 102363.433367704 1719386.32803173 111501.08913709 115580.538271913 34057.0676717034 25407.3589323797 30344.1789391535 13290.1139659493 19913.6903616302 13225.7010173819 24481.7367429651 13070.8684764786 8854.01303699144 8018.70644583177 8947.93471956585 5677.77999796471 6169.60325219145 5620.21440021678 2583.31354929644 1733.1563668438 532.871778997223 0 49.642874291664 53775 260533 99 7306.1634117109 8413.96475745857 10885.7772088071 13026.2316578328 23126.1467705561 19271.5446917081 34554.4493876322 53565.2099343311 113029.009433074 1711643.38879883 110538.778360717 133787.40830014 35549.9843898228 28407.2474677931 27986.4775558349 12613.5760561752 20848.4196318373 13489.4386614724 25401.0256888737 12752.2439531925 11502.2420311127 7585.91257162864 9082.67686824721 6216.58065104991 6519.58946671409 6749.93178476722 2963.15580816472 1403.62168879338 550.300956202734 0 44.7656721097837 53564 254150 100 7454.45429087431 8370.75598825261 12794.2756003848 14096.6460001162 25839.0895072203 21427.4613803214 37335.5301165781 56648.4120445761 111384.16531471 1792928.31318977 117701.607487056 119117.10819057 34461.1669031891 27630.5371734629 26406.657833279 13820.8375097595 19926.3121540795 13137.0576236326 24067.212896475 12457.4281228529 8228.68026905886 7067.85226675656 10914.7141067801 7139.58133472505 6833.12046534269 8374.64839884632 3758.4414830801 1797.87677966318 802.582562941844 0 48.6799262506654 53813 263891 Average (AVG) ping-pong signature and standard deviation (DEV) per [nt] 5' overlap (last 3 columns refer to avg. ppZScore, avg. ppSequeces and avg. ppReads incl. standard deviation). 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 ppZScore ppSequences ppReads AVG 7687.09413139014 8673.17237952825 11082.2110192901 14354.9673919161 26797.562406392 20370.1768877432 36892.6968628949 58637.987600435 100357.00304638 1708755.19467126 116133.407912363 133178.299695755 34054.8120774112 28575.0554403324 29901.7000115487 13673.1255513557 19919.9930534731 13097.3343328709 24254.1378367715 12566.968254734 9181.20025291687 7893.34797779992 9580.21293714654 6216.90257249442 7259.12975897672 6655.82099957338 3275.99918365534 1525.98993265422 657.137570210966 0 45.5294464423446 53793.84 259236.93 DEV 608.236565897121 871.283670223808 654.690977544641 1192.41411145664 1487.74421487993 1186.84520531777 1590.85651344258 4885.96439847267 10390.5792785095 61616.8067503602 5163.67679281753 9536.48612519782 1618.68694404332 1457.54578119806 2691.69531155485 982.799033377549 1246.28954190093 908.692303365263 2119.83326671009 1019.53892545652 814.691376634633 787.129723443205 941.624502802597 813.106603384401 977.688969354795 848.448283077063 747.447689512579 174.280655970941 157.65028351858 0 2.45680377671887 325.532078910819 2915.49459013389 # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # Ping-pong signatures for 100 pseudo-replicate datasets (1000000 reads each) based on sRNA-ACR-145_preproc.map (8414719 reads) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 ppZScore ppSequences ppReads 1 38124.5584957518 10057.0183753722 11433.4889617406 11738.3006153328 31562.911852527 31576.7254965659 51437.957829033 124262.124050342 147510.424661382 2452108.89752804 174012.478502065 56294.3872419822 124073.61916524 26046.6292561669 46305.8239703522 20556.9564893859 20998.2286657839 70474.5084988278 25546.7584179135 18150.2686468912 19005.3131221081 6972.36921530757 12572.1341053481 9668.88327990828 8848.36977645628 10589.1567384753 3875.61910996872 1761.41719840146 358.492597273819 0 49.1536137199023 63995 318296 2 47458.2519065189 8979.34365655817 12547.4642553193 12658.5541774792 31171.9979926256 31950.4289529312 51438.6728377383 141275.725454842 118803.140748963 2397741.06365725 164949.283173241 54924.1931176831 128823.334485168 23647.0732405497 46091.4741271746 18653.6824327734 21036.2648508752 80083.7897709774 27333.6303002428 16157.1417255485 22513.6646414695 7726.67709880424 11558.1605423355 10083.6627678399 7840.62504151914 9895.47941150187 4078.56612162323 1515.62507756948 287.01212918261 0 49.6167331773789 64790 324682 3 41597.7147607066 9358.20314024323 13707.94130418 12270.5302809912 35434.5176686832 30858.2198173603 54101.440383916 131007.16557681 140425.025254532 2664187.63402009 156668.817121085 57068.8246953767 126283.495841309 25581.0385857566 49367.2869338966 21421.3009885339 20377.85269358 71403.211268842 23479.206909783 18462.1939371703 21577.105306852 7114.43755905262 13233.5578864342 10785.2043777147 8988.48548922436 8531.77407694999 5306.72565291612 1458.01967488192 368.021835886013 0 56.1232065574982 64733 323524 4 48050.478425454 10218.5034406498 17908.2607444527 11851.1436582914 32369.4290355867 29109.2958417598 52499.9115073478 130112.495607866 129814.15158951 2479585.24750417 158819.10721976 57523.4685405518 127446.666080099 24718.6934017053 44233.9738297926 19846.203050023 20674.4879431212 71628.0051517798 23426.8791542707 17814.6614647899 20201.1490179225 8205.78731590143 12351.810218162 9690.76796510572 8245.1530426915 9897.18807847546 4121.09807329095 1711.06371995045 423.271686370159 0 52.967902299025 64810 320242 5 39227.6977056438 9942.92635437188 15102.1504781635 13819.0514707626 30127.1090160331 30844.3931357953 52168.376304769 133296.358632042 148674.173799085 2492789.98530953 155518.606389758 60935.1872778123 125803.615792474 26488.6366661307 46432.811622369 21097.9232386506 23454.8671090567 71478.8473090063 27523.4756138103 17616.5171236815 19412.3969921893 8207.21227246216 11988.4538465183 9937.86237612605 8633.09249652493 9367.86432535648 4571.35125198089 1703.21703924256 451.797506200263 0 51.6680133734419 64701 322804 6 44942.0094199624 10190.0540332172 14215.316850745 11804.0197756144 32019.0865939598 30873.4915087151 55923.6938326838 130183.938819736 139904.635127252 2589857.02973306 169478.241176632 57098.6863759341 121571.478289763 23842.0523987303 47088.891378446 18945.0092758692 19615.095892136 74737.5561083892 25219.91552139 16774.7962862585 21152.6507716552 6572.84225570255 12086.7270581798 10530.6662020542 8219.35825933461 8039.00494567775 5010.4441142218 1793.89473443105 304.427670282935 0 52.9924495885943 64705 327981 7 44974.3648862222 9092.23102007864 13686.0219885072 12642.0310601209 36040.5121050802 29779.7065638526 57895.2832893546 136456.086586286 131733.036208059 2451654.14274299 176781.460785731 56986.4052950446 121732.825155305 27246.9645237544 47397.6753400824 20603.8229925198 19792.973516359 68352.0797734883 23766.7396673017 17618.2538297394 23016.9207215738 8494.65436775163 12525.1905714502 9315.62589074687 8996.31770975159 9247.83922986628 4424.9049980634 1905.27421997177 434.117465559359 0 49.6130887964214 64566 319494 8 52661.212505326 9304.39791474326 15284.6381528305 14114.9434986661 30931.6471536481 32688.9165827722 53667.5875515474 144432.166701461 125458.980452046 2434078.50826317 165683.10107347 61563.9511700114 127115.165750413 26179.0180240622 46234.3451254302 20527.3879031816 17757.6662425345 74168.0436516458 27120.415942331 18208.1954410216 20955.1237780057 7770.54470439227 12391.2985038531 8824.70353873519 7871.48931273051 10039.0532284781 3490.31359358962 1563.06489570033 414.949906442912 0 50.0813010311303 64340 314896 9 41807.8541121997 8004.00388964082 15007.1924697013 12994.3043842515 29643.7573935052 33409.0709333037 56154.1472349175 130943.594417678 153684.643361219 2480418.61482963 161209.24722206 61308.9815586225 142262.143872388 25660.403441335 47687.1740436954 20796.0814344551 20696.9411054461 68586.8720390034 26093.4429613262 15042.5881025796 19588.6197473531 7306.11890640396 11109.3109817875 10057.5885336859 8733.12813493688 7613.71034384856 4191.15763138618 1963.08808444528 291.234690038698 0 48.6657275064579 64299 319535 10 44741.4670309632 8433.76894687421 14154.4735629516 12018.5498530961 34400.8894700568 32939.4513555264 55326.3550614422 116512.342262145 105986.526286026 2421862.49145208 145974.806624835 65260.4345012328 123484.682180405 27150.5844852682 45037.4992535003 18302.0283052924 20728.9798367129 73122.4645575507 28221.14985375 16988.8404258556 19231.8953727994 8277.15847305101 12773.9358771483 9915.07031631603 9241.69641396634 10681.617225472 3818.57480703962 1398.11242261014 454.186666605421 0 57.8577043666081 64583 315015 11 39034.4850415861 9118.73366415643 14272.3072481302 12044.5391151849 32032.9629704063 33646.8839529545 56009.643736376 123662.457063926 127030.689245387 2528011.72246997 141939.838918283 53966.0778899883 120502.272900566 24364.1880429975 45173.7349980875 18843.1560356899 21286.6033897508 78164.2231312931 25547.9205643695 16376.6045951127 20839.9008486869 7682.61570326904 13130.9888485725 10889.2450340803 9326.86528726747 8426.45551054874 4560.17463611093 1849.58351754726 350.175600267845 0 57.8204207144407 64460 316900 12 43624.7659769219 8040.76004815655 14083.6642742325 12322.890908045 31478.9070846619 36554.8822316002 55799.7115012018 129196.866152608 133233.808997718 2629922.00512958 146775.658276118 55130.1536099116 122008.972334748 24242.3969780266 44131.3432050055 20351.4541346908 17000.3353790354 67675.0520777422 26548.0872467595 16701.3472276845 19131.2946878051 8372.66969881448 11703.0803644192 9502.57208215636 7571.51769972641 9325.74532987352 4671.04705552844 1511.50788770533 292.995468420891 0 58.1438253811575 64142 323426 13 44090.8315981845 9015.88072118686 14247.4015844985 12337.4276348761 32182.9101236379 28497.6123974523 58094.5525410706 133484.224817144 143926.292949665 2450048.73916193 160351.313460585 57169.9357649762 119873.657625561 26709.3188492096 41375.0687563239 20622.7564298956 21251.0085242092 63355.5647124268 24635.653206021 16887.6683372431 21705.6492657369 8493.69921281632 11918.7374659543 9473.07112934125 9120.96414160532 8490.18513823766 3881.32393340444 1618.14422380867 285.576996315404 0 50.9216296488559 64207 317394 14 40626.2008482979 8592.25923578985 15737.7189836052 13211.9041720986 32401.6765491527 30337.2372521622 52588.3714985663 134960.911192388 124093.502560781 2449309.59885454 159554.623278108 63180.1819652035 115037.182275581 26817.874344815 44810.2997187304 22553.0892127682 21271.03795058 73029.9178831795 25267.6217009219 18474.2776787705 19392.6878726706 7740.37709060368 13107.4168753137 9527.53060215635 7761.99789502841 10163.2751907881 3460.45506078898 1632.10877723678 295.510017704392 0 53.4603137969056 64517 321675 15 42988.2485910698 8044.91644841519 14453.991241793 12652.6760448405 32589.0810104168 32300.9406361638 57022.5686820578 123563.977949434 114592.918948875 2585500.09953347 153698.508769837 52651.2223101241 125113.489680841 28599.6892500368 48544.0802720724 19593.0408168459 23641.7434789632 79158.7873876152 24298.5590951442 17212.2398926953 19727.4615230986 7712.26920767425 12590.7607105468 8716.17614796043 7748.94962810358 8377.08992303801 3832.17181079661 2004.55469654961 356.025354420001 0 58.5089760116739 63732 309955 16 48333.4456975537 9351.99357090535 14104.127656257 12954.5282622444 29185.3769756731 30708.0360487582 55009.1370981311 134039.733948583 111254.527123777 2512507.10396986 160174.614649709 60806.5722183048 112784.087949428 24969.7104277938 47177.1778968201 20227.3771656459 21607.4742819824 70733.0104901336 23272.1130432568 15484.1538373206 19852.1954074361 6923.58798658324 11938.5676909824 9650.85761929919 10024.1701960928 8801.39067587668 5744.49343254656 1615.23902572288 340.756341010901 0 55.9846675756473 64190 317045 17 39495.4966369679 8336.54927123818 14003.6381105016 14008.6584469923 32470.6893106408 29707.9101803201 55491.7211917996 129227.360740774 130566.659206856 2504325.27548477 168370.252040979 53722.721196151 124069.175481753 25648.6795936787 46873.0954897357 19195.3890617479 19407.2137385606 72611.7485915263 26872.6733819837 16207.8927709633 20812.2363731374 6912.16894241093 11995.8411357678 9342.05552432682 8452.64084374348 12288.8012445089 4920.10919296263 1605.24080274798 348.449377486105 0 52.218643465364 64514 319117 18 43374.0138471013 8510.70467586302 12732.6820406106 14097.4919746083 30158.6754393685 29807.2358966095 53147.3054487677 124809.116048509 139082.284025093 2530132.99793942 163419.333452631 59189.4577802736 119900.843367388 24775.3471039142 45847.2468666036 18440.2697203435 18856.1451609226 67620.155688237 25574.7625263392 15725.1422944316 19502.1955763803 8667.24239203715 11169.1619770738 10087.2182625262 9434.28744047521 9986.21626920084 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13255.1609285207 31950.4551861417 36692.9123493953 53144.817054646 143208.471623983 142929.946164285 2410185.06618708 164830.452123299 56606.815444996 120658.614711607 25763.926320663 46082.7267508996 20136.2883470546 16491.8919036331 74367.3439346363 25067.6636715653 17171.1057854034 18019.5423679019 8673.35779166992 12042.1188452558 11221.7009239305 9542.21294188135 11445.3742309776 4309.77624749645 1717.24648052914 411.516641219229 0 48.4651315313682 64600 318324 90 48880.5575998876 8511.44470383682 16557.9342849798 13150.3465899518 34163.6143198202 33179.6540678528 56802.1888258514 137131.770215202 151849.906302121 2458086.58393617 178000.798049797 65285.8478588746 125103.037218095 28101.7070959544 45107.8723778704 19453.7829804688 18733.3515330524 68497.39667381 23616.6288042276 17721.7779622074 22539.8866896881 7969.03715725555 12002.227415459 9928.03322427532 9291.01588876878 9304.89437198697 3900.61949457529 1517.28623803457 485.643389310057 0 47.5329348733338 64467 318654 91 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10898.2143141748 3550.16522026018 1517.30221550397 499.681108466003 0 47.9560871331151 64895 324025 95 47772.1381820862 7592.65720388757 13852.6147658106 12589.8859915289 29650.0526829124 29423.5255950847 51221.7624236224 132857.257437 126422.783415596 2596030.90962769 167708.838682244 61163.0257557022 124545.00358979 25720.5942310144 45849.149675424 21889.1879696194 20001.2861062575 76217.043718285 24391.7072696466 17822.6259267238 18825.2037249158 8058.01053776645 11840.3148435966 9808.50607324594 8022.03692178595 10058.0140254435 5275.24831989225 1495.88056014934 303.131822343146 0 54.1383090447358 64715 322548 96 42941.1300566159 9043.30561289338 12640.3579778974 10574.2937433381 33360.9494705696 28688.9136699802 53043.7702777944 139520.592406611 131153.230872039 2525221.6572897 139759.12301151 60438.2939561415 123551.925140871 24223.3844601753 45816.6908001893 21592.3526030644 20791.9619179305 67035.0299354517 24350.5707061363 17116.0481512573 18508.4721514923 7242.81077955449 13005.3511681964 9123.75653474904 8137.74245947347 9597.89982016519 4602.07760242544 1522.70425401441 408.654491229285 0 55.4270757444458 64452 318895 97 44159.1933047281 8514.4894132367 15319.1455175718 13017.8610376161 32338.7865644348 31118.6779595832 55454.9459916391 121165.79316077 150826.42482088 2465904.83880813 164331.040059627 63833.21071386 129499.518271284 25928.2550787943 49142.4459991435 21686.7103024562 21024.2529984872 72042.9570314802 25724.7275540329 18532.285222447 19691.0759290915 8947.61461029416 12931.860168608 9396.95057195599 8081.32535821937 11441.4313018875 5519.50546159704 1584.51818222925 354.668479914827 0 50.3980115115027 65211 324448 98 45527.7097087323 9487.50892223396 12686.4090685017 13630.4580541701 32947.524928504 31019.5397838468 54555.0283953299 167966.206331618 131803.881582687 2516224.09939717 161994.990481618 58806.5689104498 121251.766230205 23533.4504805497 43253.1874819942 21111.5544000855 20995.2836070399 63875.7462483099 23577.8550477849 16753.9473795532 20054.6720549343 7925.69151114807 10351.2301201529 9684.72780492327 8732.52294777689 9063.86250275424 4806.49217782314 1532.66703739977 238.105297564717 0 49.3738916874224 64293 315573 99 48302.9281405485 9976.71503234515 15928.3897030796 14643.7656123216 33553.6595699087 35716.1374883356 51505.8378684486 138645.173646741 129776.096565627 2545490.73768012 167395.628443912 56472.8836536774 117468.000469404 21951.9166343444 42880.3254465302 20381.6558741809 20945.9807093045 65751.9011374537 23536.3742548196 17118.3801437979 21320.2147429054 8220.48657037533 12070.149598726 11009.8005338609 7129.82329978479 10688.6599053031 4308.72979202126 1785.31928313032 404.360243138965 0 53.4163549488645 64853 323612 100 42578.616181168 7989.79087693059 13099.4425128381 12782.4356539426 32728.177387351 36369.8962283736 54473.441475612 131751.007980694 138649.304540907 2404400.69084676 161192.30696334 57435.6259090139 137765.103351752 24816.7991270208 48041.2203413906 18969.6884078258 20738.9807945966 75049.4246577404 26842.0678782494 16694.4939796386 21624.8908320103 8217.55184642619 13421.3688115583 10910.1466111365 8651.30795261738 11743.9053552775 3936.83333308135 1661.62106041344 310.81366494449 0 48.8897064001458 64350 324659 Average (AVG) ping-pong signature and standard deviation (DEV) per [nt] 5' overlap (last 3 columns refer to avg. ppZScore, avg. ppSequeces and avg. ppReads incl. standard deviation). 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 ppZScore ppSequences ppReads AVG 45274.6403641471 8717.55293198017 14192.9576600736 12591.0338419893 32830.5871251901 33418.4365344502 54167.6105345372 133959.614407736 133418.988375637 2489305.44665048 161156.265735015 58965.1135811589 123991.497531854 25007.9132780744 46427.4330148607 20194.4652578002 20253.5136280383 71212.6647333819 24819.4229931977 17133.2069232117 20294.9700479866 7838.78839130989 12166.4202260563 9748.6592986076 8628.71037137162 9637.77092030815 4313.5745527431 1667.56476058671 353.617884299572 0 52.2130943010635 64361.34 319154.68 DEV 4934.20617719818 761.54911433089 1235.58951293981 934.759188164381 1625.63928743389 3544.93860638131 2330.93801295188 7993.48314782824 12958.6997355376 87232.8326483773 9294.04629410275 3517.77313211631 6022.16078882566 1514.30911068324 2504.75288187567 1185.57550756635 1367.27854334037 4362.75569830888 1540.28449561659 1059.32704433376 1155.4906119318 568.696786613314 997.5883919646 639.096615062766 736.607177713208 1043.1995720441 622.538833734649 188.544069047189 73.625194950995 0 2.75905188275164 389.940180540554 4201.24504136571 # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # Ping-pong signatures for 100 pseudo-replicate datasets (1000000 reads each) based on sRNA-ACR-150_preproc.map (8888658 reads) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 ppZScore ppSequences ppReads 1 11194.113915272 17094.5103365212 10781.7663773873 9242.25823708241 19327.7568564076 21147.9015698254 36335.7173535969 36837.9392844421 109612.662532481 1348983.94793377 105950.023136626 49811.2650451513 88779.9753874682 74411.396185852 3971315.78835939 19105.323679905 19556.0960045643 15173.9410097297 12380.5839443952 13841.370093255 9356.50171055265 8250.02681033888 7286.97604506685 7035.6042617924 3457.01333506233 4860.40766287478 3087.02424472493 746.324683923158 466.505843860218 0 1.25666666884861 45581 252532 2 12019.9892994577 15270.5602282462 10474.2550968007 8989.18131688571 14358.3199102267 18301.7605017796 39492.5690044749 36320.9933437618 121991.081813177 1228634.64599947 93461.8404469185 47512.1227626826 83995.7736700172 43372.1459817408 4232074.19009877 20609.612211289 26654.8499807716 16675.5777701119 13461.0978336996 12855.7443136078 7705.93342630723 7987.65450572962 7681.01273568073 5795.2740148223 5263.13579726299 5063.55300981967 2585.73719865033 1052.62933228266 421.029704797614 0 1.03711518965315 46077 256895 3 11729.954895901 16131.1133569719 10784.1673635435 9984.58351211322 22211.789449995 19317.1584521376 39330.1169857678 38817.9318329512 82288.2724706563 1256361.76484403 91627.3087124159 57672.2951565585 102246.635056795 51023.3366098212 4137791.01886628 18401.3666431068 18535.4382039843 18226.065274234 13649.0057554723 13815.1509401236 7830.92868822062 8938.28168431678 7841.06326082034 6683.41994212532 4198.97531005076 5672.14660857188 3394.1214809355 1020.49393617525 440.778614307054 0 1.09669465416925 46344 259385 4 10552.4002253652 14357.0592571624 9026.77871953822 9468.84155535718 18477.6747707996 18486.285586809 38394.0483485228 40760.6717776521 85152.1307245232 1302307.37735556 102282.079902115 43658.2491763313 89566.2426675104 49276.575529095 3870377.09228325 16738.53144592 21063.9301599775 21263.1558377226 12001.9001819595 13273.9854972441 9170.6204854234 7690.1667489338 7696.07005002427 5876.38380352707 3356.56724014044 6334.65918487 2075.33155508376 892.890889089162 424.28932988013 0 1.24409459271614 46016 256611 5 11371.9167431386 17715.4843387199 9534.65041844773 9246.3923744922 16478.9780006661 16396.2064729534 39837.5268811122 39604.1208986084 82769.1952531968 1258434.03031671 101384.292739896 53535.6677185872 88590.6449862875 57410.9082893209 4033027.86017065 17548.5611622734 19278.8977615614 15194.8128872267 12061.325732759 12448.2723472356 8707.79656501342 8557.27191141381 9733.11235212094 6754.34437529912 4660.73932777186 4066.54669743092 2052.86542576098 833.197158768207 273.99316066559 0 1.1345546789614 45683 257471 6 10768.1895412556 19634.9392328792 9676.99348564355 10090.2671149019 16399.2216647015 20715.4384296519 38829.8057364229 36380.169409482 84021.2372208787 1243093.07599364 98713.2164650425 49404.9146228376 87226.4373110805 60209.8549781471 4446311.75304947 15537.0547826843 20074.5957166277 15554.347164686 13477.0496380445 14004.983929152 9130.25542502955 8434.38668351547 8973.78454614292 6875.12366022174 3687.96441015185 4755.06810233996 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6958.41776595969 3665.46861306292 4852.5221520803 3134.93315275613 886.924697492844 303.178392238441 0 1.04374611134828 45319 251848 83 13642.0838242637 16160.4212955693 9523.97424899164 8310.82760216105 19077.5642957402 18402.733115526 35418.8635085428 34682.4690073014 87904.1105500571 1258472.15527354 92385.2695184713 53086.972839267 82088.3685536549 50668.2637243624 3834155.13761556 16361.1788587079 19188.0572090759 25560.6170521366 26767.3490026008 12597.9348224848 7876.36828307403 7475.82343694623 7628.54881357681 5414.97197670559 3237.93580951382 5258.37389972049 2394.10714810512 768.385210134601 338.322314704627 0 1.20629104986331 45635 260891 84 13841.7577222907 15198.1270935121 10094.2948059735 10211.6091802159 16273.6481008611 19746.4394051272 41425.5526086063 35909.8207577923 65899.3266669595 1257878.59523427 101214.837137509 49405.6345319718 86181.6193435309 67102.6630679928 4129892.01993241 15256.1043658764 21882.1340218683 15078.1510147785 21044.9423057122 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27018.6025106531 23682.5264220073 33406.8487324185 11687.1506758331 9798.15719299436 8301.6199098346 7977.50370959425 7352.62053211804 3711.07231409307 5514.21701100682 2631.95617618784 844.709801317175 517.512929658959 0 1.13859408994412 45536 254949 87 14659.7922008226 15379.7275093475 10551.7170077903 9267.519579782 19319.9859515967 17204.5416498187 42304.0646675994 38266.644804573 95670.630482374 1177613.54030733 90402.5383487093 50413.3505648001 88372.8181138281 46028.2527135422 4198665.83155717 15529.4201222528 19132.9994609553 15642.7712776794 20999.7634105373 14682.2319038555 8317.07578990857 7405.30184630114 6752.83371327655 6847.88688390219 3427.88442890528 4616.71277644062 1634.99247721276 931.927726190956 401.847034754384 0 0.993103214398617 45335 255867 88 14669.9570033819 15861.3868424401 9816.90592177924 10389.6359538254 16075.5909013403 16926.0057451475 41041.2813166633 36058.8736056929 71315.2569353294 1206529.83572554 98151.5745507423 42904.6164939393 91822.6132177903 41125.5161836412 4094834.93245026 18334.5408976531 20855.6533268261 23129.0621677926 14796.3796917423 14135.3560613331 9297.43205183539 8334.75468734623 8013.75123150784 7680.79316829928 4360.53941241058 5938.68390402116 3748.64203997187 899.756847330133 628.312959567006 0 1.05758259332788 45857 255003 89 12753.110506954 13861.3989430074 9417.76977914543 9412.91962255446 14996.3345304723 18030.8273863085 36177.2608577137 34129.9367164825 86337.8614992767 1160163.4731619 93810.533977975 64010.9015107119 99795.1458482684 46022.8425129989 4237716.0072331 15506.715521968 19922.4755519482 20506.1021820666 13064.1784960145 13099.4320002499 9384.11286316204 7095.47669952314 10138.1634890887 5469.01543570652 3171.50746512518 6094.97214641229 2556.94589038271 999.578556485238 473.78996130606 0 0.963189799520853 45534 253410 90 13196.3813753701 17764.6117020608 9310.06771216425 9130.23425477656 18338.6340241504 19993.2174780833 39577.4640595908 37497.7736732869 97219.4345956502 1285007.7922412 105014.65459123 49008.0874415569 92019.1494279527 62843.9667737285 4242421.21868311 30444.9997116793 21296.5485943255 14947.4121886567 12888.0054085508 11847.3293223591 7529.60892174615 7718.61454247962 9562.94430718436 6530.1773832417 3896.49404875725 5582.8678696707 2901.44609859204 1119.47160331943 367.275894735577 0 1.09288964849461 45568 253088 91 10202.359412288 14395.9354814378 9992.52970253167 8861.25368934816 15756.2362741539 17637.0357616814 40324.3496770013 39910.9473346531 96097.6630444964 1243061.71767833 96213.0244431183 49670.0456561979 86750.1242411609 55665.6117208043 4118332.10530684 21304.6021661005 19640.9570733266 15966.91242016 19674.8920921614 13565.6413610262 9659.64846194739 7475.58040598935 7687.46182032979 5845.9202925762 3698.93869745637 4636.80162578619 2533.20549714085 1269.00555730884 376.270021895419 0 1.08862531730941 45038 265784 92 11134.6070048049 17409.7133745826 9954.98916334271 9098.51878033269 15937.1496557426 19795.6847351548 40130.2062209147 38466.796266977 76748.9257176977 1255034.8802227 109893.813480264 41219.3993395456 87246.3241271498 56143.6764750431 3932015.49670514 20739.8604845095 20225.9909844172 14001.2808240344 20528.373223885 12935.5100892851 8247.2378323609 7256.81990893624 6889.52836323408 5365.70347059136 6124.84063274128 5484.70570395755 3480.2955860436 798.769379816718 432.669102920476 0 1.16609128345383 45284 253859 93 12635.0614831782 13558.2181995055 9585.44711140395 9013.27798761465 18224.0437120059 16531.1519400393 37070.9639794469 36857.6355814313 99536.8700376796 1194920.39714494 94863.6992323297 50102.3657169815 85458.1079394565 55712.2405001603 3983986.34478276 21942.9734787846 21465.713853531 18175.9724328833 20659.8999329014 11588.2003005308 8618.53281226243 9532.92292273622 7291.5686301557 6882.01738781676 5219.07536946147 4995.79806447299 2032.0964507952 858.534118809095 343.709802763387 0 1.07901438535653 45715 257789 94 14143.097265526 13929.4687534754 10224.2505666604 8913.060157217 16844.3650130235 17031.8632324835 41338.0442723376 38370.3353839863 71362.0796162871 1187853.49400207 95983.8484603558 56511.1901918722 85098.5364525836 57017.238063154 4099440.42638151 14157.8555414576 18343.507928446 22984.0114297678 20575.3334969439 11222.7436738191 9194.17384439788 7533.92247977112 6321.62230294536 7381.16221290838 3944.2757082547 5206.41519569863 2465.66123943967 909.750702876699 476.871550601181 0 1.03482212527733 45592 252999 95 14144.458486358 15472.5659302039 8439.14685786996 9430.99773708312 18018.4170745424 18326.2628637951 36548.752082077 35204.2020473499 97343.1460216361 1287558.04890826 109619.238006982 62518.8992829001 84558.995311446 63768.3447189991 4182255.99307646 17040.6790353483 18571.8005801042 21393.2293562852 20237.3448183096 12151.4187004341 8281.3767980951 7787.9849793374 6899.35930186563 6676.04723575398 4344.78058398974 4999.07549896005 2129.64106132094 1106.65818340578 271.287912205799 0 1.11487165250392 45848 255476 96 13380.0757297167 13104.9395381166 10519.7352468675 8796.96813100132 14253.6623891903 16201.6511805869 38340.3795550967 37000.3715500304 102174.642007972 1301480.82514943 106811.868288793 54788.4580119746 89194.1632104759 60917.87241635 4278257.50240008 14588.6610261032 21698.9697962539 15454.556315663 13742.6642284916 13745.5621020645 9834.14175306935 6582.70440532507 7124.32476872604 6587.73713101628 4196.65137654443 5378.15397892827 2900.16858218675 1043.95378209232 345.282408511681 0 1.09974023887148 45522 252385 97 7575.69621414006 15245.7879103635 10122.7120720234 9251.39066804411 17001.7982948391 18693.9968278616 40752.6825552001 34997.1412914818 77529.5330928975 1218198.56230993 97032.4823252771 54376.074714991 87408.0442873979 52633.4384098973 3717038.13065877 12025.024760454 19752.2807629456 18424.6462070343 19470.8408659692 12057.8994568953 9370.34775553214 7678.96595946657 7503.5239676977 6954.65553436257 4611.88932752473 4886.59517178141 2952.83238939966 1036.23048658121 382.748689479563 0 1.20390838364535 45609 255086 98 10658.000995165 15091.7437491248 9661.66120325938 8349.51919068873 16498.5710455056 19982.3284667985 35977.8288347137 38039.1096995698 87364.7329561068 1311915.78119094 103142.789713117 46236.3969213027 95653.3791434988 56359.463381616 4190319.95822776 16034.4015582744 19905.8911975462 16273.2852184199 12487.7674314652 14570.8265239363 9498.73626885713 8066.98614862742 7281.21083961245 6912.49345840747 4496.28031524281 4664.07228938986 3683.75396810403 1092.61252865357 393.069798638414 0 1.14022503830353 45802 254063 99 9988.7900097147 17589.6340782005 9431.32316324219 8399.78429425054 17554.7238152104 17811.270010117 34901.3155137239 36549.8578607651 101033.331519147 1245412.97106249 102332.486034073 45012.598473574 84744.3084687674 44724.2266648985 3960680.32362671 15004.3990746415 20033.3354547848 22299.1516110628 19613.9494934304 13112.601021467 9885.22241812985 9478.84161616473 7683.47267418673 6096.87417354826 5826.1011057106 5274.49103072525 2147.77449784274 1059.80566008193 399.246165806277 0 1.144921486845 45393 251070 100 10213.5016546577 12682.4462737037 9818.22961369332 8739.15669157706 17024.9852914928 16565.800798063 35753.54349164 36576.5923233954 87053.8465449795 1226843.88135599 96990.8263498285 40515.0613684012 88345.3006590764 60021.9863905512 4042151.34549502 19789.6054328233 22196.2841808459 23382.6414566075 11799.3571504489 13821.5175422512 8747.25599795668 7460.70136965617 9101.69890589123 6625.5186629151 5669.98628462667 5525.90150434102 2584.43822565235 820.881372969905 328.380936000862 0 1.09657589641531 45992 258191 Average (AVG) ping-pong signature and standard deviation (DEV) per [nt] 5' overlap (last 3 columns refer to avg. ppZScore, avg. ppSequeces and avg. ppReads incl. standard deviation). 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 ppZScore ppSequences ppReads AVG 11948.1961191539 15693.0525084693 9854.78054741449 9131.20512515025 17157.0513913049 18227.2059823137 37848.7951252111 36976.1202585842 87894.2340956687 1243204.51824929 98862.4634120836 49958.8100076644 88399.6181028596 55704.2346426204 4115933.9111141 18076.3980420578 21329.4519811555 18644.9311181404 16634.581264225 12890.3146242191 9002.77232165439 7897.92553739806 7996.68033210351 6637.80857329414 4273.84252403183 5208.02660332943 2715.20037521068 964.324161089839 369.838364419566 0 1.09201336166553 45569.06 256215.86 DEV 1881.18044571397 1795.52659145487 570.808049125886 705.259625961858 1717.35516819616 1457.64365363784 2429.37052587138 1741.17880312586 14816.227669725 42691.2296370686 6692.6491509343 6452.85648559446 4350.83213120888 8778.70835665263 162195.464072287 3965.93750748197 2684.77766860191 4130.42775682557 4986.10504963474 1035.53991729135 747.937421451055 636.54402223674 981.307618656109 651.694391640215 687.921471281081 618.151103209245 514.18270444763 165.239118129281 72.1012993566498 0 0.0718831447260135 321.686207972925 4506.3658351714 # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # Ping-pong signatures for 100 pseudo-replicate datasets (1000000 reads each) based on sRNA-ACR-173_preproc.map (7987330 reads) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 ppZScore ppSequences ppReads 1 36772.5277617648 19316.2339537702 10642.7520269067 28105.7201485728 22005.2817694551 30509.4783163383 35099.293890026 66492.0504959769 163123.763308846 2006466.67552895 135212.433198388 69104.6383726839 50012.2134545901 35246.9826043148 15677.2315637061 16810.9997460914 18430.3865410145 14717.3915726211 18760.4489427973 12317.8593089604 22390.8320625996 8328.93037576429 6707.61507661513 5940.92000928095 5463.4679451751 5377.88710918128 2742.62289249361 772.365263022309 286.512421866825 0 48.51649733468 55190 309684 2 37313.5535183784 17163.8061870022 13082.5340023917 26294.8382707308 21066.7196122805 31439.8661140435 39743.5544090079 67990.8711489013 165329.669213775 2022161.21204935 138679.626842911 71293.1296389873 45584.6914490961 34929.9280285727 16177.9499963462 19042.1322137507 17485.4416904496 15437.7202012743 19122.1381259033 11509.6726312794 21985.7278837159 6837.12022003723 5792.3648792318 6601.9773259609 5263.31377311443 4229.48041763255 2918.46848803724 1096.71171470038 681.900736350447 0 47.9548297204971 54838 315584 3 36746.8033667062 18072.4445308943 10716.3408715187 27823.967933277 19372.5161958869 30826.0468768381 40891.2580452066 62421.84282396 161135.712987022 1928719.24409613 129119.636926537 69744.249219713 47665.1720993839 30733.2417891006 15579.4930430517 18715.6804020657 16865.1162824888 17281.275823262 19663.004844068 11375.6627534391 22097.3070638569 7816.13572614027 5868.38310853831 5698.85768865236 5680.40285094748 3654.40641533622 2289.79918701819 849.929434489146 550.038786272883 0 47.9344493575873 54961 315008 4 39823.7393599447 16491.1705973258 11517.6617976196 25125.8098089945 21275.111537456 31103.4007362432 37548.9045028059 68518.2190085175 178412.584647967 1971602.44935691 136414.273156173 67495.2424999808 47403.3875199151 32832.9192751683 16164.2447814781 17674.1146905191 15348.2076670161 16000.0635849211 18648.8034169416 13517.5815392478 21446.9049678248 8679.53802658069 6253.50862658105 6564.27508054909 5721.21135219388 4046.52862213731 2809.04167850942 1367.17177752052 1240.67925039093 0 44.6753883216455 54934 312894 5 36569.4213583703 17859.7241361791 9697.01141232762 24362.8580940484 22846.9649992996 30985.673359054 36392.5180873618 55415.7245796391 158954.44441525 1936603.63566419 133145.513009615 71388.9866178802 46383.858915579 31150.8535591056 16423.536453955 17744.9263178023 16731.2040846131 15583.4056795755 18167.405427538 11680.4880700866 20972.7208290631 7712.79587626904 7211.9814906384 6267.2732953704 5359.33652989535 4523.61834490285 2542.18504144744 1165.42872299917 471.942696194859 0 47.9699063256004 55301 322168 6 40398.5041298401 19209.740138365 10153.1998979685 27156.391640965 21464.4009992427 32033.1188885156 40099.7840627363 61892.9179180383 169800.876596358 2006709.67037508 135164.696362592 68927.5970158917 48756.4103665067 34574.941938341 16025.6994692898 20165.3594423348 15285.6061193197 16480.8435570928 19809.5768120317 11540.8095561827 24973.5662658819 7010.1938657531 6381.90313323841 5899.19411504341 5132.22047867228 3854.58084449214 2927.05490013317 1385.55600525456 495.097711969721 0 47.5301774589175 55138 318760 7 38652.9289437116 17252.1082592395 11563.5577545826 23712.8002825478 21403.2698184655 33569.0827554244 37278.4112977596 67549.5050301351 161903.326086203 1970503.23203977 136474.348043817 76619.8863997343 44004.9468481811 32690.5368612588 16279.0552507896 16663.2786721963 18792.1778625649 15863.4363884127 20840.7641927404 12926.2119735464 24760.615947869 7743.36581067718 5735.46937809286 6039.03107430427 5462.23851502702 5221.85983081898 4205.69391492576 1064.27059227701 849.357724738439 0 47.3836345215714 54621 322575 8 39528.6976514675 21737.5930240777 11617.8732067229 33941.7527354402 22322.0161336644 36746.446695204 38154.7670388011 59220.5911927046 175215.370530518 1891612.52137827 132098.800940395 70211.8028699994 48174.7100878096 32329.2843049702 16306.5154447551 18337.7064596746 16469.2236470524 16280.9961595506 19260.2085620076 13080.8307403944 20076.7570636555 6549.92501146869 5697.07778583213 6398.40653838297 5501.36313275015 4412.82055674433 2196.99425312428 1201.94423128673 488.238685555962 0 44.4999285695406 54878 313177 9 37027.0301883879 16653.4986342431 10261.1995681885 30167.6047738947 20646.6364386775 31526.9199281625 36377.5701768217 70152.6320897429 176897.594373611 1894567.19877375 133223.010269216 73255.7038041329 45046.0812703299 32987.5729371678 17456.2683460832 18977.8494919158 15594.2920438055 15151.6161908671 19276.6734536309 12969.4769018209 23980.4553105355 7841.34362186692 5559.84927292063 6486.29930707501 5758.96077471167 4438.21921954231 2360.71172782324 1414.6063294865 611.352530050149 0 43.3382088707169 54697 311214 10 37880.5342214117 17134.315997275 14456.6851447609 28462.743172248 22312.1918728038 30129.3623424795 39109.4009098564 61922.3250018227 162014.097738646 1959082.26318246 131755.484886824 70848.0126817259 46980.6448459623 33140.7870073239 14960.8308394418 19489.0609365324 15945.5573331795 14048.4804641103 18733.9204645165 13748.8402377813 21222.990574441 7619.94396639936 5868.46179325776 6485.92994393612 5832.63419358464 4499.17932849837 2482.90601603432 1397.87983006512 482.816759903461 0 48.2987390529519 55115 312933 11 37184.9226295097 19001.8139533627 12088.6863124765 27579.8909352786 22921.2532693674 30162.5533965855 36070.8925929717 50525.5850861782 148880.155718313 2002510.02485967 141769.584106907 73957.9265432432 49289.0367879255 32703.7660249873 14853.0539724328 17244.958070998 15776.850851555 16281.7022543507 19023.6724677568 10922.4268643301 20763.8543087401 8302.58843776628 6537.10194701417 7613.58018929121 6696.69122706111 4755.69027803656 2925.16590150851 1552.83918469308 687.19493754149 0 50.2349747710241 55191 326210 12 36902.7215639626 17214.2635239759 10543.8392136358 26769.7401635501 19860.7156106532 31835.0967813223 42843.0547892087 54336.2996277088 156112.894456304 1934985.55227891 138993.23366095 74789.0545350576 44717.7615762374 31591.725884872 16829.6391432652 18161.7534294691 16707.1216960616 14512.6163868348 18500.9950094376 12464.0280295221 20818.6618438276 8155.06207956251 5466.50892741243 6571.22195003949 5222.95382418462 4516.97059462724 2314.00814184832 1608.30003119943 558.701011994132 0 47.4691009132757 54960 326471 13 33460.337172979 16240.9246803235 10895.9043081397 26499.4842834067 21777.4686301172 30766.0488033524 38017.02782646 56185.3210751541 158026.03596364 1985100.71442332 135933.387949294 71331.1066099293 46197.3216083913 33948.4709090477 14787.8053773841 19540.0208920531 20779.8178619232 14658.1421805503 18881.1614385095 13295.6053866705 23241.9533219039 7582.74758997236 5807.80603453901 6201.09068932338 5578.82650704552 5498.15026373079 2379.83941066413 1478.32331555093 455.694175697666 0 49.1597627286604 55209 310280 14 38358.248346672 17953.3673533821 11522.5306112301 30572.5535379917 20705.3963639235 32553.5959108443 38979.2703785381 57729.3638841023 167249.426507859 1942218.38029767 137574.645384329 77079.4278061064 46889.2183972927 35110.2036442734 15930.1885927732 18994.7306967188 15676.5663963641 15171.7849527902 18424.0062859637 12097.3776271504 22229.0485050954 7845.28597909419 7411.8933082031 5866.26350330816 5345.93070064211 4744.43121393179 2594.41788197486 1332.0407658472 471.588258979128 0 45.8331613086915 54486 316556 15 36165.4317789561 15583.770041643 10012.1254791895 26864.1952495802 20836.5949723643 31818.4095110084 36839.3963058436 65824.9284699599 166771.624661809 2002463.07829904 130213.457243497 68490.2182785986 44702.5005716632 35021.8393965315 16039.8191439241 16936.1643044526 16358.8004530367 16864.4665902302 17479.1056575688 11281.6378429692 22676.0279735128 8062.07035726342 6239.3295696376 6165.32483956263 5758.07202599091 4631.36300640937 2774.29062480155 1390.13549641286 859.730533866442 0 48.2709427058046 54309 318775 16 36526.5842861643 18349.6444854799 12286.3047748519 23314.0782249667 21090.7020997359 30325.2794379352 38006.3454909665 61595.2201160814 164132.88692324 1980025.07490169 131427.194144815 73924.0400445939 44707.296771093 31713.3178310416 16529.9594608977 19465.0667763046 17163.2661084741 15243.9507239848 18380.8675699123 11827.3924967166 19871.2974841601 8159.19894438181 5826.27214266603 6986.30489101107 5229.54829507073 5203.95213040631 2291.67044796835 1181.63546871335 1278.10659902784 0 48.1579158458073 54965 321362 17 39767.8354827297 19021.0426813567 10922.2217939863 28651.4968165377 22493.9460241842 29690.8248901739 39714.0377382475 59713.7996397614 154982.039027686 1971402.31597152 135210.411849915 74581.4683835467 46037.3322490145 31985.0551423386 17024.6043839237 18196.5923105841 15620.7487243023 15949.0436638864 18130.3206173757 13675.7046286481 24116.5889728374 8486.20361949489 6411.63715525658 5710.58972440084 5383.05470331843 4819.65016026062 2459.98612685026 1036.33122597274 425.997655843334 0 49.3147824272965 54575 311225 18 41170.9524650953 18306.2335843418 11106.6901349633 28467.3995518799 20688.1797049133 29183.7886923362 37468.4004259455 62680.3237751687 164273.321389291 1963917.4404264 137381.033065333 75739.9898950869 48826.4385999528 32798.6098362504 16996.2533859956 17191.7545285461 16724.2012845289 15225.4502306478 17414.051881216 12191.7941903998 22624.1148109168 8390.62008248766 6197.00954456853 6578.91791550745 5336.89333218567 4382.55296961404 2524.31210475047 1896.14192892549 529.79388257707 0 46.6986527695505 55072 308068 19 38265.8918841826 18770.7871447865 10642.1451526153 28090.7734032301 23400.9001306928 34470.5081993437 39876.7156460164 60746.5185007221 158217.284087548 1976216.09559116 133046.198340894 72936.8961834076 47862.5418876391 32491.7728852598 17187.1496008342 16462.7297022755 15413.2132050721 19746.9795094875 18309.2730641378 12872.4266494554 21705.0271692611 7939.56487654357 5385.03474982187 6759.01982829131 5719.93207350165 4151.31554235277 2491.31316525421 1172.53239504465 1072.17570164656 0 49.2989872547447 55248 312856 20 36690.6128870756 17389.7781691754 12676.1719043327 24796.1423952856 23295.3509292833 32512.0194827097 39125.9339460402 58086.7963878758 163119.570275139 2009549.48181062 131911.207652773 69359.252708418 45220.4624293937 33431.1966489724 17708.5020274526 20330.2966757821 15334.6457622041 15461.0660818398 19004.2351599982 14002.5554733414 20923.3662806468 7464.57664574523 6174.65248009045 5658.54848123396 5962.70072741683 5246.30687074787 2712.17918822582 1291.04926985916 793.514342405563 0 49.6372335800347 55289 316874 21 40137.9881631749 22925.4761859315 11733.5936452805 24945.3534738525 21339.4630477867 33003.7284820039 39205.3228286109 66259.6352210544 174642.360178519 2041795.37887878 133876.003426491 76441.0366481787 44830.0467032386 32641.0131400626 17979.7575745607 19268.5556452309 16354.8834992999 15037.3903664884 17709.3629824537 10562.8377739597 22084.8375025982 7766.22651199054 4933.61233958579 6610.63849678489 5345.98293765842 4723.96350929877 2610.91605654603 1085.33033211087 650.493550762413 0 47.2279058334996 55604 326603 22 35481.7170937802 17349.6811434522 11569.5993045042 31164.1191918649 21721.3873999802 31474.7076677843 40388.1590177655 63254.5953184065 188811.084793593 2071800.48548547 138648.415067414 70067.6675296848 42662.2617415158 30329.1245366004 17598.7315596067 19334.1337599596 16477.2569145783 16286.0556366795 19119.9596981165 11521.2790151822 19128.5787082007 7844.15192666125 6383.03033842863 5839.51170496222 5946.06999420989 4386.88195949687 3235.83840983889 1052.91677389841 1100.58692886528 0 45.1626619928686 54885 313390 23 35681.6223701523 18733.770646802 11525.0313930535 29103.0547512893 21506.4115761166 34066.7265788156 37857.3158061651 65115.5247552596 189822.15895548 1980262.27355856 130820.913301232 76645.0248160098 50901.585582606 32276.4050667678 15472.302164694 20190.2530527091 17662.2366962708 15859.1987507938 18656.1948964426 10884.6389963818 20560.8019868012 6995.25292953445 6752.15026604296 6221.29324445564 6069.63697185692 4616.23645506174 3061.08921157497 1023.05392776691 259.452532499693 0 43.454697681154 55429 325676 24 37993.0913812584 19174.2632705889 11846.7912368107 28130.1991504777 24006.1735873674 31420.5375599004 38165.413200472 58441.3432325972 169938.580322986 2044466.93171139 140920.181941172 71547.4061367932 50403.5053364488 35675.7672537047 16620.0028096204 18767.5122668103 16342.7691315539 15677.6489892882 18037.4296796226 11698.9035109525 21457.1088295942 7532.74970429533 6447.14137304277 5894.66073430723 5968.65953036633 5643.37377984069 2718.47677302142 1001.82391133647 334.537549979126 0 47.6616469148687 55525 324852 25 37094.5808367905 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21925.249690294 7656.78613400328 5749.64412386284 6897.95138994681 5923.48106802594 4426.45512547095 2442.81119077742 1933.29707612002 559.45479774947 0 42.5747883981042 54897 321710 90 38190.9949734006 16505.8899923649 10784.8866850692 24233.5357545412 20039.5164634101 31538.6011729482 38440.8896898765 66846.4250403607 159937.019235478 1914558.72183038 132060.451963278 74192.0607666161 47207.7237178234 33890.3344373291 17281.847317748 19241.263268124 16167.0149433112 15198.4124349061 18067.3830062824 11068.4881901515 23786.870072433 10146.2697990345 6221.60290000426 5731.47662419519 5465.68212430701 4446.47854174418 2485.89972162593 1061.72253256505 815.334716938726 0 46.8488074208371 55256 314957 91 36022.565250131 17993.4806702995 10480.4189531194 23426.9204006011 20691.24366392 32277.8786769269 36317.9220550616 65773.3148845307 158571.164265171 1955548.92817515 136271.702682359 77965.5215894013 45924.209044409 30122.031704311 15451.8433207246 17892.284857232 16053.031885892 15889.2028671189 17993.3371592512 12432.6785325358 19973.343258731 8717.59040074987 6801.72454505287 5619.84672714211 5941.91458320284 4688.25078496773 3130.10852596472 852.312930066368 623.971657270104 0 47.3045437950687 55189 307101 92 37129.6581880735 17919.0452104194 11306.0971977081 26696.1848496381 22262.8671014062 33649.2903593419 40933.3491939333 63399.4982537695 161765.165729968 1961678.59964549 136354.255259931 69466.5135509552 48022.0944411867 35252.5627473638 15399.4086943933 18540.5885504893 15804.1147664779 14969.4310333259 19617.5144249188 12775.0136995744 20788.3660672401 8436.55187690943 5682.25370810488 6151.43000980027 4027.56307941332 4254.73129576655 2385.74104458434 1792.05681797586 656.829008073363 0 47.6671143776251 54850 315568 93 36320.2224722994 17146.8106264472 10283.3794434486 24963.0309391548 22795.4971170269 32050.7686221588 34881.6695354427 62105.2694310426 173448.481784489 2091024.49265777 141015.111948567 70715.9668808083 49361.3233808325 34927.5554862363 15355.3915219189 19022.6423045733 17946.6889018673 14608.085776427 17226.8506815841 12764.5635658867 20505.8213652029 8903.2961132233 5901.28668815503 6725.75445432425 6218.92234144938 4731.45456318166 2433.83227846238 1459.89141974195 862.889683447162 0 47.7904365854746 55665 322672 94 40431.5764916259 21175.7516576017 11976.7450748013 26700.3843527673 21024.3737759025 31482.7339044188 38931.9442369412 56605.3227772219 161484.022804294 1949626.96184045 144058.070764389 71374.7483505086 47775.9075641782 33761.6385688195 14321.6059191695 19286.7279167611 16261.7567590571 15226.3492218054 18542.5699796295 12772.9022115576 22577.6329756739 9195.16064929764 6412.99226970752 5808.27189949616 4503.52944112682 4716.4153542457 3069.19292764697 828.236384614817 911.018555508032 0 46.428879650355 55127 310534 95 36808.9198525308 17371.7951039968 12178.8344030488 25084.3330994347 21327.8508136478 34982.4261946916 36208.8985213308 58492.0165069306 154835.008225387 1974600.35430828 124868.271418168 77359.0862011655 45888.8746570706 34808.1016585516 16551.6670614614 19977.0574367542 14193.8078932162 13719.3735031383 19449.5201306427 11957.4328645476 21006.8930826989 7844.12731672133 5642.16013089266 5945.32586068526 4490.00250633321 5042.96296694641 2428.48570566771 951.333023140909 1021.10698690093 0 50.738338619909 55012 311621 96 35897.3735716177 18724.2137708485 11270.0052174122 27065.425708614 22506.041200442 33984.6848852506 37557.7561697972 67226.5764553158 161759.640465322 1920093.73379748 135023.617299731 73590.1863358267 46931.4260492517 34136.2045097246 15396.1036107478 18257.047015216 13401.6301896744 15969.9562471391 19204.5508097376 12254.8027076069 22253.2428063725 8325.05066516588 6515.59588311187 7009.61423898496 5206.8504021916 4666.74020222663 2849.74910756198 768.027585912056 395.088229010149 0 46.4198405953422 55637 315493 97 40760.9489538124 21352.2204862972 11120.3188690243 30666.0639729603 20773.9050390732 34105.5647235667 36382.3600198134 57430.9658826249 163072.477480775 1903433.92114615 132670.904168707 75203.4835443887 45210.2531376738 34075.4011757734 17904.0891681936 18801.7187234921 14948.9526158398 14779.8171428019 20715.8972224827 13827.3264455585 19661.3334934696 6599.2579776973 5484.15689411927 6334.90238605974 6502.44936117764 4396.36806214975 2534.46503682569 693.923074669826 661.218280024477 0 46.6942684474132 55297 318029 98 38616.0798624839 20329.0726537539 13211.2744239569 30710.2505954982 19358.2036794752 30797.272533764 36858.7433526431 62812.7074796173 159294.043539564 1901408.91630387 130339.700874373 74562.0554605881 49488.5866558455 32944.1610873778 17840.4147247676 18924.746261037 17531.4304310996 16020.4673947793 19028.1337705999 11580.5860436721 22064.9623725742 8409.45674655703 5863.3823914287 6194.40046594388 5186.79302688522 4375.09127330215 2625.48910215211 1222.83208479742 708.517864986245 0 47.4783309862696 55287 315662 99 39241.2429713764 19249.7908167205 10825.5244760505 26043.9699894222 20692.3724928181 32753.8000135949 37692.5401126446 69241.8634869985 157859.112617962 1915833.66891053 134465.321822154 74506.5208781522 48471.8938814529 35166.1244305096 18067.2562722944 19905.8290084237 17807.560211481 15316.6081242392 20331.7552997259 12232.5372662987 23462.1842101556 7319.67591399351 6042.28438893705 6533.51633414092 4960.14329518205 4322.99745733614 2439.16091211933 1282.96067852558 286.660177698752 0 47.2386113481844 54767 306635 100 38236.3035888583 16980.6145740915 10576.4445807553 30916.4944681844 21357.1672356946 32921.0137521622 35375.7486120733 59591.8252820928 166327.160899967 1872111.94992499 137564.226580458 76912.7494911375 49032.2278751827 37506.6544499301 17138.8496248844 20108.9639178184 17604.8005550727 15702.8552642746 19852.4582929199 12101.7509881798 20948.7828689047 8584.13621227471 6088.95335671208 7152.64705239869 5068.52472026174 5237.07284498689 2491.66463635411 1109.76343221704 1156.32980027804 0 44.4036665355475 55243 324178 Average (AVG) ping-pong signature and standard deviation (DEV) per [nt] 5' overlap (last 3 columns refer to avg. ppZScore, avg. ppSequeces and avg. ppReads incl. standard deviation). 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 ppZScore ppSequences ppReads AVG 37966.4675596094 18531.9998445536 11417.5320666778 27786.7468299616 21619.506444315 31999.1212527067 38269.6499057532 61326.2784860903 168376.318826771 1965659.74086886 135715.261799749 72963.429529523 47106.3608916399 33595.7205755569 16426.8263448748 18707.6896016851 16595.7357408826 15731.6714555062 18760.2832464286 12209.7171611641 21850.5020565353 7820.33304640562 6238.24583329911 6266.71498337639 5512.02897310494 4712.70375804757 2648.28902849789 1163.873154664 668.824771897251 0 46.6037189240698 55031.45 316115.35 DEV 1823.73600740948 1683.63970956343 953.844481174936 2645.13162138575 1262.45761393756 1563.72635886792 2117.53478571193 4591.15700203291 12570.8747472985 53857.304942312 4605.87527406694 3357.59802085769 1871.17336114856 1894.16553740143 902.260610308301 1245.70081658842 1528.06155955675 957.53718268386 859.318578572709 1014.69751629256 1340.29398123901 803.217127310019 513.684288895494 581.413838896436 589.463231945797 510.147078480517 428.90606541616 277.017422409764 284.246723690616 0 2.32658692927183 315.885434137125 6592.88790497002 # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # Ping-pong signatures for 100 pseudo-replicate datasets (1000000 reads each) based on sRNA-ACR-178_preproc.map (6574605 reads) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 ppZScore ppSequences ppReads 1 16669.1069495318 29071.9875864159 13894.4850872799 21803.9192235417 30435.5381940331 40291.7528525107 69753.987071557 52098.5424858658 114248.763098362 1991196.42428242 113018.204379173 106552.257028699 83562.7513747599 33183.2616606531 130349.639766169 20482.7860776324 18012.3809651296 38955.7139643905 21260.9898091721 32101.3097277496 38871.1203784146 11692.8909772231 10256.8291926203 10814.9322661642 7736.77975532477 4473.91818851205 3496.1438779266 1411.50210213057 379.131929207873 0 51.6584311868113 55722 331816 2 17877.8546497017 30316.5950769697 12237.5940008629 23840.1317302563 30064.1968285175 45980.0245657206 72294.123489735 46427.4498301086 107837.567421037 1901385.43007856 111309.222708447 96074.2056776438 102414.0494038 31241.1946041167 127213.657122593 24220.7611911284 18723.948175199 40564.3772341334 20724.8025990182 35716.3761699219 35901.6955773121 11998.6267402837 10761.1177034959 11765.4510656574 8557.38245929981 11306.6935546497 3599.9500260876 1102.69894298596 287.540708868212 0 50.5441417993436 55592 329678 3 17532.972647807 27610.3021860681 9738.19671547677 22233.3114208864 35949.2420857783 44722.520494052 64738.3632515395 46677.8967882343 97845.2202060674 1918049.58155247 116409.29782109 102678.5691998 79740.436519838 32961.9358307837 108029.720172616 24803.9859384412 19096.8493736032 32426.1012910192 24458.1933777209 31251.3380464117 40717.212510469 10063.2895100788 10103.6651253445 10523.3823876182 8259.00858131179 4702.02380663459 2836.87355328463 1019.16773149452 389.131041207649 0 55.791985044562 55356 326351 4 16355.8858895398 27729.9913945748 10194.4580494522 16662.4822985473 28303.5405519329 46224.8295153522 66766.187586919 49161.9905321877 97167.536657927 1882895.32581887 122390.022420897 101861.548898584 80718.2023453276 33778.6071436717 92344.8061195903 24947.4584879365 15436.3552108152 42382.4959039533 21493.0576286793 32652.6991898981 39252.8781616725 11212.6014860659 10097.4940645164 11200.442632134 8134.82780443096 23913.6795569853 3589.52600518643 1063.52026892826 600.83895611485 0 54.8953378267465 55455 324193 5 16041.6513184823 25451.491121957 12308.3913316691 28913.2342248352 34567.3426870043 48150.6174794588 67033.6832425249 45026.202859773 97142.0530479766 1932159.90950279 111734.383109716 102560.334187235 90372.7312582765 32293.5166877745 88197.6112600836 21071.2955196385 23790.2158445917 38962.7548354452 22535.5075319589 37630.7309453379 34587.36443123 10537.846711512 9291.14786306613 11084.1329126097 8641.9149639944 5472.74087806693 4082.49146623153 835.158511738926 334.616478080451 0 59.6439734634901 55697 332791 6 16011.9914974593 39927.4085124765 12041.7600544232 19879.4122493902 33892.5809659233 43160.0517960111 66429.4439418902 49202.9400596713 99268.0138776473 1843184.84031254 108082.537331258 97092.390509353 86089.3622346283 31743.150671515 89242.0208776705 25570.8198070808 15788.3816194639 29769.5726095355 22516.706679964 37214.0897180104 42979.7076030613 10416.2440519115 9690.41765153528 14243.4784120339 8404.40734463039 5187.07113519502 3922.10962415159 1046.50896959034 636.580509350151 0 57.6174987870927 56023 334510 7 16702.5354024805 34859.1088504951 11890.9157763954 20658.5667212118 31853.8419572629 43658.1322969581 70867.6787751057 50166.142714066 106249.989152738 1931416.32386188 111630.66809027 102185.714940626 92981.3193883948 34666.1039880156 98446.1831086931 25912.8696939598 21289.7973537669 39340.9326494984 18369.3178384133 37079.9336495721 46321.9360604355 10909.6183128959 8806.4185003047 10684.5121492501 7417.76325566752 4646.91380637912 2962.62378324422 1144.99103022704 351.49337538896 0 56.2435227324979 56300 340615 8 17611.3436594839 28849.1041441305 9808.46856572103 23304.5616695046 27679.7122052979 41223.4985038892 63149.9197312411 47812.2618787381 99343.6176137671 1910672.0363633 107225.457802177 92202.7574764011 86559.4330998159 34497.5915217022 136229.512183661 24387.4598704298 25096.006921566 29010.3431849294 20360.2471840319 35840.7742884574 35361.0041219675 10492.5676199772 9134.21254656798 11834.4357818148 8172.33967723124 23157.6959302178 4045.13125575252 1055.39275895838 537.243640117512 0 52.4882454973043 55720 332234 9 15619.0390423031 24761.0120770164 12089.0332928214 25357.043072047 36386.0397606452 41840.2822417002 65187.4993802953 51007.8079066391 102588.718056729 1990148.23166734 111752.350917112 108830.449342739 85116.6246480021 34335.27333225 92730.4039657836 20852.6100128432 18386.3252356111 33999.2214997661 19827.6355220962 35355.6942047378 34933.8803664569 11103.3668627141 10389.9348784281 10711.2632957599 7767.618319783 5216.50476577721 4415.3888887014 945.127134246717 456.045141295658 0 58.5042718953899 55331 328668 10 16754.8432215692 27441.4219999497 11134.0892253833 21842.9944528986 44756.8349909611 44752.5469231976 62368.966938363 45956.6054343269 108572.418794658 1897850.58374413 104411.513586987 104342.160259391 78871.4755745223 31365.9806363917 120156.906343379 21773.378929817 18867.0372489659 35703.5147275971 19458.2339649748 33701.6051005776 34620.6533886393 10972.8471827978 11566.9666654055 11064.6955426613 8574.46221716884 4902.99753844825 3573.88981967629 955.002254563716 432.19058238787 0 53.3890873046838 55965 328270 11 17321.0824294828 24400.4781003935 10687.8959524048 19743.6376315041 32453.5792980497 41916.5781199933 66635.2944929196 49526.8348249483 98908.4812956466 1934095.92812271 121057.978830636 100200.974810335 84035.497453532 32080.3905516885 126731.99386004 23426.0819791813 25873.4234537675 34456.8470032563 21493.6188890512 32418.5825984973 32933.9665930779 9897.17154533405 9121.2347524014 11184.5243989196 7754.79174173424 5115.42633734887 3295.55994313712 1007.7388410974 415.572779785242 0 52.1249983398898 55856 333595 12 16272.4998174866 34345.4699781522 13058.5411296255 18790.4286311707 31355.9983576813 42124.6225311101 61738.186216421 51330.2021755692 102082.784974376 1898405.37270845 114950.22094199 98576.3304781881 77599.8234727334 35041.5056393155 145087.880708682 22659.1828983323 16640.9579923868 36488.552704896 19997.1764596482 32982.0350111607 37069.87269432 10024.5595097797 9416.84754667804 10734.5268369379 8339.47565048962 5330.59385516012 4090.35933764435 960.985329391464 495.758187745483 0 49.1885314468992 55452 330942 13 16685.8310268859 27160.8876913865 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22197.7908794963 40231.3224226501 36208.4974799126 10710.4974537983 9846.27784564676 10914.4552508176 8096.51635078038 5185.14038319094 3403.71793633246 973.465459104333 377.177985804691 0 57.1038608142289 55855 339288 80 17816.4017962336 28566.6897277644 10617.7175221077 23590.8194510775 26818.9850612971 42395.2605289553 63986.6935051545 46001.5504520186 110718.568431704 1897334.67111639 113209.639000939 92809.5716309279 84351.1337888155 34723.3829276105 109653.537541816 21129.2780437907 21358.3877808513 36268.5524993917 21158.310940086 35938.1548346294 40132.7647740401 10954.3972298698 9109.8585027296 10947.2490255361 7582.85628707616 3972.97449022731 3933.29904261529 1091.72056189163 346.164319962589 0 54.4202672929697 55071 325413 81 15394.7773473132 31035.5444363829 11292.9808189865 18977.2059379357 40133.9228194818 43441.6174734943 66417.8910665777 55490.8780676597 105811.433503697 1974647.6545831 115972.306828738 92922.5916869664 83014.0503389776 33768.405192782 103105.369847122 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86727.6723050172 32414.7888444913 120392.268826707 27374.8260863604 26264.3678099947 32300.7069391129 19798.6891111423 43783.358996637 39266.0955028128 10582.9169598006 11017.1879424737 11373.5933357694 8470.47491207165 17416.4474971039 3284.65624174222 1032.02881869318 457.4270933808 0 52.868910875125 56016 337684 84 16552.65989608 31650.1689011357 12836.7971229243 18357.9940936311 38772.1805247205 45789.0639984221 70654.0630083234 46890.3663142706 102371.914444951 1909382.05872252 115422.008494942 103423.70911632 87980.8959015065 32135.7810683412 126928.690014556 21613.7105750645 15538.6578083928 33904.9485389096 21193.0937251532 45386.4612284164 39773.8491122506 11405.4601773987 10691.9324301613 10911.8577880831 7872.55137596214 4688.90373329041 3814.32544462741 1108.68394421416 454.195665820927 0 51.200874845043 56154 334834 85 18839.7133203843 31160.2622851313 11785.0880393712 23123.0691824277 35858.0031023858 43528.5016966742 71874.5477230246 50337.2938975155 103710.123429668 1896998.66073383 112069.075275452 98658.2335913307 87756.7108933553 36012.4962986624 100924.75216001 24106.4330401254 16754.4234996135 33249.9996400889 23285.0153338273 34676.0944321211 40768.6010806017 10574.7623129928 10046.3173241621 10593.7808573008 8805.51534578621 11622.8420114467 4476.80598549381 1153.88574322603 556.366178451687 0 56.1485286330272 55318 333197 86 15205.4492217689 26799.9299467643 13521.8211896145 23468.8481873043 35996.5469735121 48365.3041965656 63400.0260789782 49558.1028997451 108500.929894386 1956915.34967558 119905.907965692 97064.4317999934 79575.9543023777 35394.9674037363 89717.1379646698 22438.2147637721 26826.1653957742 38307.4024616404 19303.8726709506 36672.5519427137 34997.8457119304 9699.83983828579 8747.83947681138 10867.4250858809 8389.65938083311 4542.86506612675 3809.78656048726 1096.76370574593 510.376296923443 0 58.915118943814 56198 338194 87 16718.1152864288 27720.9316192252 10258.1785812331 17629.6481706445 31643.4323363844 50224.2879024363 62889.8530674635 53608.2450998102 93764.6348119042 1922418.29302213 115166.271437319 98503.0096082072 98661.7118339864 33860.8328341002 129925.335710198 21850.6252638734 25590.1898942223 37471.5624991037 22325.5534890396 32852.4033280998 39078.1001707492 9268.07024245448 10013.9079912957 12565.8984280326 8028.82595833918 4421.94778840267 4420.29098452815 1160.87305552036 635.808681173401 0 51.7464886202587 55490 330833 88 16511.8364145732 30322.1213765949 12468.4150197109 19621.7112067855 28532.3537319781 46030.4151526481 65162.7450886488 49083.0480515172 98607.8086674795 1914987.44297754 111523.472049988 98219.5534153094 94450.1471533011 31814.3483866563 88905.6926217907 22796.5470890474 18185.9094667067 38882.2672672801 20977.3403748527 32418.5680633668 36532.4363792698 10129.9209579975 8665.13510221071 10921.4652517381 8264.1478995887 5689.38668517393 3511.0623528152 913.969307119363 462.75117356035 0 57.7648098018714 55104 327518 89 17302.9871880378 26048.6990092451 10250.522267883 21840.9299717415 40645.0881557303 50864.7226776264 68270.6761667426 46580.5967946068 98797.9615022858 1917053.84167195 113105.262114176 93247.1159965431 90629.6493764147 35803.0970675179 99330.6686945273 21942.0357905488 17725.7568530975 34709.0569712676 19519.1555877976 34051.3803616749 39374.4820629501 9929.80171715218 9287.59718514494 10996.6406459477 8702.45090899263 5720.93870594844 3097.91062922895 1097.78954170146 374.598047103328 0 57.2607866203397 56053 334273 90 16350.5845130351 24874.8933738521 10986.0978828751 16937.7671132611 35346.7759004568 44311.9044745312 64667.3908182184 49754.4911914663 99225.5785444889 1929957.80016108 115091.07431569 101040.673649183 87769.8232774951 31223.1418907522 85271.7806292046 22069.2293414513 19310.5955504289 40407.2683717564 23462.515196721 35903.4955088474 35716.378948687 10767.0330497958 9865.6968336574 11036.6668052189 8681.33758403358 4159.45210708379 3404.03674560808 1489.3184420501 509.952668548574 0 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2594.78281491533 1184.56024681125 541.95874780036 0 47.5907579030644 55762 330870 93 15721.2891653316 24261.6921933177 11888.1820949757 23899.949911318 33003.7149477276 48279.4210475608 70078.8905350385 46213.455487082 113368.904966988 1945666.05304465 119683.333215754 103645.663919815 79696.2679181437 31363.2382249855 104022.228769201 21293.9975508131 23224.5075922622 35471.8443781529 21049.413514228 34877.9960834898 35632.6288569734 11472.7186870978 9936.13171531221 10873.1183055048 8609.4786631418 5079.94967568313 3816.33650317607 1008.88554082588 384.008462898869 0 54.0122297791996 55938 332030 94 15588.7474569748 32528.9037293008 11052.3931251684 24136.1163173686 32556.3681175859 41371.4423252338 57597.5205828863 51044.3984219045 111273.536874316 1919798.36909113 115936.459660691 98425.919442609 83049.9815130232 32964.6291515003 112650.881173644 26878.1516632978 20236.8726445516 40461.1923661699 21251.7310063156 32690.99104988 35922.128504263 11301.0205032588 10203.0035707412 11336.872283803 8013.97010408814 4440.71971597778 4168.13950384958 1061.72743755203 433.769982701578 0 54.3197714671224 56182 335287 95 18837.3959144938 20450.94899402 11569.5443580011 21722.3452880485 30337.7882202942 40024.9726675624 70350.9654930694 50088.469767249 88648.3126555354 1877281.77985694 123139.602123655 102473.323679674 87419.9206777736 33050.8738179228 104010.855415399 27532.545456944 20651.6019359063 35362.207871838 22007.963036793 38906.4751616705 45730.9931267351 10727.1413044262 10429.7880861482 11174.0922481403 8122.41238162513 5230.11108260323 3297.10964219002 1424.01729566389 638.650824134408 0 54.0640187458294 55955 335346 96 17466.1144366305 26697.9299910681 11518.845539763 19520.4519552344 37836.6204232652 45386.7770431272 62704.7175832807 46619.2441247311 105084.109070625 1950967.25344081 106616.435136952 98635.429264736 89464.6788489256 35868.6320904979 106515.685427794 23704.5577949236 16737.436801518 33813.2901708318 20994.504943746 38927.0752197489 34247.9452304087 10935.7791810758 11118.1931620817 11297.8855177192 7505.9024176912 5136.76047208623 3761.05286544533 1030.04365058451 384.404202780821 0 57.2824599650414 55276 326399 97 15217.5785905978 32269.7340905093 10605.3196688177 18194.1560898554 33411.0981628993 42915.0697655983 63500.0997377951 48591.9254205455 95426.8231028177 1888989.43427971 123547.050399522 101004.65951182 83922.093756425 33198.3292515011 107386.361185723 23941.002670277 19497.3278101698 32019.43231093 20141.5227729772 35671.7409381971 34203.0905862409 10438.5799668198 9538.51742299839 11990.7785428227 7337.25825141154 4191.43866562287 3873.79497084135 1197.72560727676 629.878684864129 0 53.5465404422947 55487 330839 98 16957.2682537454 27333.8551978429 10350.2677817349 18466.8691114475 31830.8305571611 45074.5908829771 64352.7786287583 49292.3780405517 104778.840992427 1874325.3149603 111770.070358009 106150.735031736 84157.6715821978 32967.3278980438 118550.64179661 22269.4568150826 16205.399782985 31803.3409714363 20722.075991032 34370.0907277982 35482.372161271 10682.5064408594 9699.92145526471 11394.4557401272 6543.0896138083 4159.56985084774 4213.00570831949 1066.37696575342 267.626454661387 0 51.1200320069889 55875 334637 99 18225.2459795574 32776.4658469379 10083.1945736687 19839.4367189426 28733.669795741 44778.1885449944 74259.5725102884 48478.9167954766 100929.987952067 1892900.53412508 104964.841610019 96862.3563544992 83755.9620551127 30978.7015065786 88943.7750705315 21685.9688135061 19328.8852520582 34845.9719295509 18580.7404672432 35091.3453735523 35542.422468061 9631.00258144979 9922.76300169389 12088.9695388558 8886.58289981381 5269.56147585475 3497.36952423357 1229.67883855061 317.920082020014 0 58.6194467592479 55473 332413 100 16481.6238170071 28588.1234491185 10002.196853548 26480.4015661214 33576.7314599453 42386.0941741393 66227.7893677066 47535.53806315 99908.5242461103 1914155.09872839 115363.220400483 96189.5595192161 91148.0700725199 33666.4297309442 115850.57533243 20130.7469392589 18600.8904379842 33162.9966957175 21556.9750035102 30279.3455109523 39397.9640370709 11030.4387592634 8540.37398787107 11358.3567824111 8930.45358639919 4489.52287222712 4371.35565703365 1324.67582085812 347.284488787661 0 53.7189746848203 55693 329272 Average (AVG) ping-pong signature and standard deviation (DEV) per [nt] 5' overlap (last 3 columns refer to avg. ppZScore, avg. ppSequeces and avg. ppReads incl. standard deviation). 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 ppZScore ppSequences ppReads AVG 16689.1636352346 29215.4048151223 11287.0607530326 21173.3751937441 33479.5100981105 44573.6282256446 66860.1745791398 48643.3925971354 102486.877841444 1915442.71957831 113740.089580578 100446.936381933 86134.3108016282 33174.2963889873 106937.500918198 22281.4096806548 19882.2084625718 36297.0333128814 21016.3610364726 35216.5276465079 38765.4751900377 10497.9808805071 9784.76247953535 11030.0421292784 8292.34231356044 6259.46804824929 3759.66201380434 1090.27787820072 430.812353405806 0 55.0498426424581 55820.98 332973.4 DEV 1481.12564003583 3755.896858152 1427.2970717739 2600.30128614139 3184.78817412593 2687.60564052866 3051.61344292576 2620.72250462954 6815.95173389282 39135.1199752289 5035.35888368091 4503.24053175818 4942.13642040665 1444.91247981134 14865.1176622356 1905.89206475353 2939.11215997984 3558.59442641118 1307.89365307723 2873.82210999036 3951.18943490056 731.474087343665 706.162144917125 801.977310141935 608.429242516572 3598.52146919719 470.618595440964 147.358526300092 103.584794301021 0 2.76904543653185 355.282140840206 4353.09233074604 # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # Ping-pong signatures for 100 pseudo-replicate datasets (1000000 reads each) based on POR-73_preproc.map (4059217 reads) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 ppZScore ppSequences ppReads 1 6596.95704465174 5983.96134292307 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17847 158257 96 5841.47779190388 6750.2679137294 6410.08657988288 3251.68464118181 26975.0096932897 30098.7223788559 22693.6810535459 22518.1233449506 63200.8718056168 1132782.59084009 62048.2847079501 14300.5320011008 16537.1220935595 92780.8550518307 41283.7826957183 15232.156769227 12168.2821594646 8654.78524241045 8296.85412594433 5446.65640096314 9754.24754468543 3962.56826435227 5384.56244174191 9456.91978705692 1770.0466822924 2852.35722856864 1734.32617226507 4220.86974373556 246.288059684135 0 46.879412962922 17212 151665 97 5976.45228229218 6019.11950709124 5989.04902068048 4438.28049479553 30551.9054068257 29349.6765144898 27575.5797414776 23798.5739595846 57058.1985190379 1299580.96526612 57972.5439941007 16070.7771931917 20574.1597139703 114729.210442168 25996.6351410607 14116.2898870042 14277.0024714976 8215.02207103174 8612.64443323156 4912.99209924381 10208.4203015081 3938.42300617963 5904.87151207569 8685.84278480341 2502.87482912678 2096.51583331629 1733.58468500571 4297.05733337901 293.689864976294 0 48.6913724519553 17650 151946 98 6721.29802472462 4995.75204315248 5437.98663278516 3613.61106836836 34533.8821735276 29235.6061228046 25650.7947866261 23923.417400392 66652.297315009 1236196.81815441 57364.1137256293 15725.6541326623 17553.8573588547 108965.65929757 42640.2397504833 13856.9485339478 13976.4188664908 8367.72604201431 6184.93922412311 4773.7528939662 10216.9246295891 3402.60725873214 5578.73529592474 9369.99781710103 1732.29777296156 3986.12157799273 1787.11171908118 3488.76195369179 178.550326579839 0 45.8466234648705 17499 157305 99 7669.84411356283 6755.73382455309 6867.22110529352 4075.06260588376 35367.3422801192 28971.1206709739 24062.2776201896 23946.2883335537 78290.8087860967 1270609.94100026 55917.6069371788 12430.9986903168 17361.9696784465 111944.855250051 51897.0592005583 13988.3016880954 14999.8653869017 8348.41554251194 7473.81360131964 5547.34566840328 10233.784274654 4324.28979560896 5067.2723877108 7040.66151692139 2205.97155680184 3084.17846214724 1653.83404811698 3829.94546365896 194.934947231162 0 44.3792811888592 17412 155470 100 6863.61698029397 6244.8847794828 6069.78080076484 4237.21316501872 33161.1624105246 31368.8297869469 26313.4545701624 21406.6625410664 73964.1935735233 1245426.1085917 66307.1042236991 18994.8348342904 18185.4693687965 107766.972785148 30812.578088134 14308.5354213824 12706.8066488784 7025.94382986704 9086.20057902828 4640.09426075184 8559.78697829216 4478.89576515682 5274.179581647 9914.15443048556 2079.16306077945 8756.7475719449 1786.37088930732 3926.24958042539 291.553707423231 0 45.0945007177458 17703 156020 Average (AVG) ping-pong signature and standard deviation (DEV) per [nt] 5' overlap (last 3 columns refer to avg. ppZScore, avg. ppSequeces and avg. ppReads incl. standard deviation). 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 ppZScore ppSequences ppReads AVG 6857.4847873761 6241.01952500351 6120.80501253303 4423.84044076671 33319.976423618 32757.7341607663 23900.7086096537 23370.5066638173 66342.8460059732 1236380.20159964 59868.6269988362 17845.8172933129 16869.6404413867 109843.494746587 33892.9471477471 16135.0859678717 13513.5281041129 7837.59010256872 8061.7554644244 4764.55995888727 9001.66984085865 3482.4287636922 5361.29996541461 8927.84562819549 2113.64195097883 5807.23537880728 1761.14443174415 3491.98379156534 214.684316037413 0 45.9007108793695 17557.6 154244.3 DEV 709.734661490829 527.233884482769 552.952775290474 628.613566048143 3045.06254583777 3271.93358349183 2199.72063772613 2508.5652129998 5249.47769567736 48274.583111688 3597.323171206 2998.34352607074 2579.97525832292 8288.98636577056 6827.64216146951 1551.79071441797 928.46601327438 832.696764600602 827.944473318756 593.404640959624 657.937537928476 505.94808300171 474.798678098204 1202.1752007577 286.541536716083 3559.58209092945 239.157605597918 772.744791556759 68.9293316938316 0 1.6951290837984 153.750121951171 3677.34469012629 # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # Ping-pong signatures for 100 pseudo-replicate datasets (1000000 reads each) based on POR-79_preproc.map (4745025 reads) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 ppZScore ppSequences ppReads 1 4415.30179555 4056.66819669836 4634.73616620695 3179.80742882506 10354.9187988538 9827.6263970797 12903.3003547554 21610.2977270146 18488.6925600109 520771.279820183 17327.4284310472 15225.5197689987 6806.86927567629 12021.0327716149 11357.5568786634 4406.0268777146 8954.05433669362 4743.24130719914 5234.81097584748 4362.18300294832 4770.81700619964 2654.152075903 2794.33105216409 2435.61456189165 3578.80805585995 1311.31687073694 928.713761098504 203.329684558709 85.5138196019148 0 93.8850010087056 18532 121162 2 3336.16355428162 5516.86969288522 4867.22254565402 2559.65077686208 11133.4614300464 12736.9623790032 10991.9711654733 18228.79263508 19158.0309938302 541932.087064967 22685.9394524366 14679.2078425515 6473.54765914521 12885.4465652872 16116.3908360466 4389.87433311533 9142.83514252347 3927.07714104775 5167.99735254746 5800.39162668876 4252.85030196309 3128.5455433109 2899.48340678809 1983.00854134165 4112.63110609262 1331.37059213371 820.573063426601 154.257372457753 46.5566719398469 0 90.3489727610269 18191 120882 3 4311.93050387989 6327.05651766654 7110.00089206142 2624.82953078699 9563.74086553502 12081.6380586897 10490.6732488514 18066.5550019359 18670.8133347737 475117.71171905 17104.4718179223 12961.2584126171 6778.10719979693 13825.9779523099 9737.32303399202 3513.35417609472 8654.15884127366 4382.43967286834 5298.55502228852 3185.26101480844 5564.4169579826 2679.14026202547 2230.49812833893 2939.02612873781 3357.3135553567 1367.818198807 817.84783550852 243.379168175103 46.7937196465422 0 93.7203339773416 18090 113284 4 3922.32109300413 3986.73366354614 4532.02764804576 3303.94328280956 12100.5381341369 12905.7170939002 12445.397239668 23389.3751606115 17534.5709532696 600627.790619741 21175.7373909373 11769.7188080268 6469.66409578307 14361.4581746003 11069.6041694997 4124.61780008016 9434.41167966151 4839.86949441109 4955.6078933408 6527.3295170881 4976.85689783726 2466.16304295082 2495.56231108892 2567.48844851311 2875.98895926378 1062.65500319929 1169.79267093962 594.839073747988 106.106246947497 0 100.049748056112 18396 123604 5 3408.83465820232 6463.68992728573 6770.39649941946 2927.76044399631 11313.4764636395 13485.1183392723 11409.5335413348 26014.2103983378 18292.2764731494 500964.567214262 25323.2365085116 12660.2699988605 6521.75840038076 14281.7511642211 16345.6046828197 4239.04719735958 9112.22402510014 4872.62231490118 5556.63296848898 5019.09911947103 4512.01485038603 2555.57333302902 2685.31245969568 2437.05079473295 2921.09806673732 1507.96048763784 861.488543100378 296.086927543373 41.9627826976886 0 72.6749836839283 18098 121020 6 3818.78851901741 3408.53511812504 9731.34236481988 3031.4569802755 11674.0099260866 11727.4809600602 10248.3802613005 21258.2523723746 20773.0407051959 543201.464136825 18374.8784911742 14101.9140624798 7168.65877536956 15514.7818286895 16282.9702219564 4681.38550656506 8840.20981620932 4369.95479895219 5065.50842731971 4730.68327931992 4908.18372384826 2938.22893021172 3867.27985562547 2331.59418708657 3044.32558677477 1028.59798921701 1097.08567378349 625.130541528893 41.5809115401844 0 90.6976538756318 18286 127200 7 3624.36506368505 3998.89656844964 2417.7101337066 2134.74708328568 12413.3122481563 12758.3945530696 10995.9646877654 20183.8414271865 19328.9069124032 555504.034656609 19125.274691757 13115.1795820849 6975.48408469027 12212.6627440104 15273.5710454129 4860.43679913403 9098.79792922133 4262.10313547242 5275.10861250221 5698.70700702174 4278.54039282751 2928.64309798977 2343.07583614058 2476.83997648646 2751.42946021241 1156.84720435945 908.061303412229 293.64616154117 63.1928681900111 0 94.421985896741 18123 120738 8 4072.81346864229 4088.98069127301 9554.16030829767 3058.84448777775 9691.58739062065 12468.0134315392 11827.7755010653 19917.7212195679 17824.2650260967 551748.398808488 21953.5317131075 15786.5875994563 6330.79867222934 12793.3368807433 13900.6412229822 4744.66811718395 12131.1864509159 4157.50081107428 5073.43130658167 6340.52840010854 5009.16213900159 2623.46474130674 2619.4906047737 2348.04644020169 2748.85340058966 1113.77426538179 1042.27277134984 200.947040490395 68.1960097768334 0 96.1393878466267 18369 122738 9 4610.87412772542 5890.13775411258 2380.98008231865 2863.48002202389 10603.7610169622 12334.0164891605 11628.5141219689 21695.255831345 18055.550656257 495963.340397591 22736.0060157948 14618.0830109046 6289.03469804914 14579.2251185433 14787.7252420206 4664.66301598257 10696.7575222807 3836.23934793656 4939.71080379267 3354.67399459325 4853.1678830174 2504.02547476706 2237.45824342271 2535.43537819394 3135.08526268291 1141.69699972748 1197.56035705614 308.859819507906 20.0444784580499 0 77.7101559460914 18348 126197 10 2775.19430054827 4425.0169680731 4931.21869285754 2569.95200836342 10317.2084495081 13335.6415067921 11429.3324401679 20973.310849732 17572.4654040595 500991.01167794 21149.0862334322 12132.6186757968 7806.27379913895 13528.6288745827 10437.3001822007 4476.84916020329 9784.90880548631 3766.43857293457 5171.032925162 3577.39697449463 4608.56172613804 2189.3949372774 3136.33987535338 2384.42454777267 2837.46721256567 1473.06998391169 970.357110219576 624.376448492399 52.449880952381 0 85.3304426436512 18370 125755 11 4864.88485582217 5169.47278457004 5175.05115882546 2755.46996578879 7877.69327933656 10926.8419959039 11259.0538359667 17141.1329817469 17098.8298188289 509827.512532659 24193.2465220212 13035.807343214 8610.00895579386 16123.819930489 14819.7498017562 5295.22778354038 11517.8553093921 4536.27566074157 6087.90916537746 5542.99674583305 4753.22492593981 2401.39635726479 2802.14130105516 2245.71544744943 2699.46856999424 997.439023011597 1281.11733576649 610.1139006329 63.4719805194806 0 89.195773909734 18298 121203 12 3846.86802634894 6267.04269354568 2776.75417799255 2891.29035393586 10651.0303847347 11149.090106744 12566.2903543478 20795.2442739827 19921.165367054 544199.874591525 26142.7106007249 11601.8851592755 6999.67098469289 15012.1598468132 13993.418449352 5082.72625237861 9353.17227140817 4741.08212513065 5722.72629389919 6086.57767496858 4739.96325909276 2152.94557261109 2531.49866225689 2604.54449074863 2962.22006758623 1240.23103805863 677.253618625559 212.28615769013 37.9929723739714 0 83.583966832275 18197 121510 13 4115.84005866593 4271.31481831344 7802.11738745053 3873.8540959942 10725.5595047909 12688.5801598864 12228.9923904784 20910.0644383601 19028.2465518408 551231.372543615 21149.9940888836 15195.2631256982 6376.1612941602 13963.6115495281 12136.012089997 4043.12881636652 8661.08265343819 3725.85361430886 5094.06606821908 6033.81081979619 4039.93394700515 2500.61846121623 2420.84815725965 2322.84993932665 3180.07448012229 1286.75090264917 834.456087056508 205.176730609223 59.5036185767637 0 94.4233901336535 18169 127315 14 3828.62222088627 5533.19840825589 4938.2006313136 3146.457104621 10551.6220291334 14003.4539601406 11851.2811173632 20554.5086410806 20619.6871298809 477002.953325935 19689.624679544 17442.3927043201 6314.89464223031 15613.6079261174 14250.8077899744 4364.13913454032 10079.7250735537 3969.96355055237 5133.38320626116 3791.52516862135 5332.56009828609 2818.33135419887 2611.52770993745 2224.8320741244 3043.47201776229 1079.86311081138 946.212760420769 202.184470476626 32.4210217568927 0 76.0435411657503 18323 122438 15 3991.76913352939 4949.3709237552 7172.13562659569 3575.55401203046 10803.4873485568 12852.4853211929 9871.88894182705 21295.6593680525 19935.038843691 517456.662772201 20351.605108669 14458.4158833507 6697.94394036677 12864.9443827179 13012.9676377563 3819.89729876142 9365.94297332336 4523.43306674612 5421.74638735459 4050.51651371647 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4742.35360115503 5685.16552970441 4830.56559071367 4886.24998286219 2585.36112684481 2497.78441810297 2431.8777070539 2988.62546539298 1384.92638441849 971.429356531179 213.310063174271 65.1888431013432 0 72.9769533095357 18172 119237 18 4082.75891257034 4976.66333733278 7507.778025877 3248.85964262342 11216.0479436347 12671.7456076223 12049.5144670828 19034.3509882809 18670.5849395265 519957.643209199 22333.8487421311 15585.9291536569 7267.73450329734 12889.4589206116 9668.03318968203 5024.80170776475 7903.99282653134 4943.01576221755 5152.78135782366 5288.82876592049 4263.75357234114 2147.19179209791 2563.9401349805 2000.05926045516 3034.62988057849 1175.97887598256 712.821117035264 1101.75970105037 48.175 0 92.2002396830272 18267 119446 19 2928.14950256874 6162.59044288759 2337.90122570736 3071.29603952736 10251.2573323039 10659.9286527327 11173.9724873221 21381.4980276512 18082.1857920613 477443.578965901 18731.8031054165 12680.4974994721 6761.71389530313 15020.4326776846 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63.4036507936508 0 92.2362785842971 18219 118727 84 3352.93537862917 4331.16779709797 7169.02273458267 2470.69575540352 9478.77254461186 11729.5893870932 14591.7441237882 20175.7434190687 19779.2270670187 482607.734141987 18575.6868502844 13688.2832970426 7752.34513367055 13573.8534245382 12232.3826495515 4772.01950242251 12784.8814103663 4791.44320230557 5664.88559450933 3568.51009922785 5460.2208352101 2913.26428126851 2478.69860246123 2631.60214448793 3532.00219383066 1220.84192038211 860.148725103494 342.713340626269 37.662938265012 0 84.317173263803 18129 117337 85 3230.38279287551 6884.39859679732 4957.4694269807 1873.27680334314 11434.5777585056 12531.8162173096 8708.30104404407 21155.5025426605 19945.4348907235 530048.673361818 23099.4579665767 16896.9946362574 7373.64626510412 14262.3025628806 14639.0911139531 3685.69191354265 9363.97307606582 4540.06538982341 4998.58539743171 5426.49544544654 5090.37188645988 2663.88019488249 2702.50116929724 2757.54414511601 3309.31734925832 1186.2714732244 1391.63450328644 169.197495812773 45.2034314757183 0 82.1341060982617 18179 122830 86 2947.15466112277 6890.99260171689 2477.15969434529 2441.02492004571 9998.59676812999 12964.8244133076 11672.4926199208 23824.4839180651 24256.0648697071 541016.174301203 19778.0767081627 14894.7940227601 6210.29104285338 15279.150907935 20099.6880746247 4449.22455449382 7980.90871640402 4697.35173776055 5068.59894905609 4174.69866904901 4711.15785650255 2632.7183601693 2478.44903745545 2748.52623897484 2878.7350590938 1316.75300375889 1029.75147038601 288.417499031943 62.4282738095238 0 74.6779952330918 18304 125632 87 4462.72309478814 7154.14442026652 4796.40955744276 2294.70221446364 11959.404959001 11409.3411035616 9015.77121079167 22062.9764028499 23259.7295596718 510253.035866559 23493.937773436 14439.5194664667 7168.23511682593 15499.7060494883 15460.7601132433 5355.63671327004 11521.8635092203 4320.11581511894 4995.4778177171 5273.23384525088 4777.36917637161 2455.00216341312 3097.49207132821 2973.68767924378 2851.32925260929 1443.87574488705 678.236205189932 653.115122092359 58.7308948234448 0 76.1982305062013 18287 128042 88 4099.90653977825 4630.95064619999 2878.36729658772 2862.21006108721 11019.2092810597 11961.8693308083 13496.563842134 21409.1178883986 18274.8595106727 490794.569441643 18449.8395779098 13791.4443932501 6343.63537894034 14002.7326360787 11891.2427146908 4620.82838383958 9004.76560439039 4761.20802925206 5987.95918153784 4133.75846853402 4280.67395575433 1996.17276864959 2522.45798520905 2920.90086119144 2983.4049835786 1405.99766617613 978.09229111358 201.633620073716 50.22790424882 0 85.2252808488844 18581 124141 89 2667.08802248974 4116.22083832082 2962.8593799966 2995.31180430951 12015.4208545212 12855.2757207737 11925.9890456271 19055.5008556938 17694.7379818011 498519.754153205 21981.7736637017 13473.6462982056 6773.3407206705 14111.7933681262 13030.8466574799 5019.34020271021 9525.31373670521 4137.64385089524 5316.10066360607 3611.46439565929 4986.11765107248 2314.281294159 2529.06294818844 2482.61529509001 2797.86078671104 1336.85256516704 888.550599419528 725.065061013676 72.3541666666667 0 83.1988478380123 18298 118601 90 4290.70322854061 5453.25696154308 2726.78060626757 2793.70122533765 10459.99792749 11020.7369209026 9258.14276919077 21402.9264659344 20397.1112695487 500880.707393745 22521.0482148863 13716.9550934132 6812.60379532566 13630.9296462486 13128.3696320541 4688.6354432383 9724.71305329475 4536.14127333575 5225.53662568143 3516.64413538475 4780.34697174119 2217.36831731881 2538.58074935176 2377.66562964852 2941.836116169 1179.23576500176 753.953470510767 148.68360977903 54.864933525256 0 79.5854374509319 18286 121344 91 4312.88475169476 3583.83689077651 7500.30105317508 2951.1486050302 10955.1604127085 12716.8573467686 9558.90559980996 20344.1550031485 16967.146295713 563646.817546119 21071.3766945235 11940.0936836995 6236.1499483188 13940.801399391 17820.776652116 5206.80476544424 8638.78515805202 4683.53446883351 5828.97560418275 3787.62899685079 5065.08349444299 2412.23937722766 3156.40023055719 2475.01650885771 3017.76179242591 1350.83535995603 1222.43070694061 266.058367097313 32.6090409095545 0 96.9725972905322 18111 123579 92 3938.38545729966 4014.08700526544 4364.2983507644 2657.6527469466 11754.4534617486 12248.4557473721 12113.0824313342 22649.4817577952 18813.0210330745 555233.693753657 23806.820528914 17349.2994219946 7256.68898125592 13320.8794051479 14457.2480184244 4343.46640729912 9746.03805436581 4848.1980186114 6237.18301329462 4904.2249112869 4945.91523321963 2650.33659254997 3182.40376929593 2670.52188438008 3458.55790255855 1368.34660404387 933.334719281406 164.87010192446 30.3470953777405 0 84.6873897527098 18262 122176 93 3182.11991775519 5293.28831621599 2318.93381262206 2473.63057752604 10925.6235414165 12029.2288976026 11652.4328806375 19877.4851952516 18830.7916164573 524629.473423729 17185.4625878089 15068.4962305639 7076.52724315472 13345.803399957 12022.2406098772 4112.62335888301 10112.695885131 3790.64674553308 4715.21053098312 3444.54067288428 5944.87773782812 2207.05553732202 2711.52407963945 2386.91079140061 2955.16536835807 1056.11727678454 701.941382655713 179.379498039437 64.6881840353844 0 91.3515620303088 18386 123388 94 3649.22394700249 5913.56665547031 7343.85026985922 2960.56293140758 10041.6703250498 11964.6099598451 10137.4426026453 19278.2025950155 21079.3496929358 501424.845761241 15463.4372732496 14751.8434661225 5963.19500915059 14683.1865604433 11360.8651348489 5050.15342384253 12358.0756338789 4875.05505750359 5157.16348004967 4028.92576019331 4708.87188712037 2382.86147780528 2676.19518425474 2243.74481390998 2947.75139800278 1304.30465902332 935.531311349466 1020.01605627804 32.2300120444072 0 92.7805173068451 18044 119115 95 4231.17556278811 4692.62030740925 5386.73090714394 2509.35811532825 10548.1683581785 12658.4970478505 10819.5165432778 22621.4835295519 19290.0876847974 522701.915267183 19852.0206897944 13612.560016748 6346.49595351437 12032.9589950701 15361.0785490068 5230.27211830693 9811.75740829659 4233.69494961556 5193.90682752702 3208.17905975776 4754.77872828656 2342.49761401617 3160.2545521331 2351.48494813692 3089.39648178811 1193.50471033186 848.048087010817 236.351432797101 51.8611691086691 0 86.1160080512009 18199 119919 96 4276.66196386185 3761.53115664694 7364.15157646947 2689.59093479445 12018.5053268587 9645.10003531644 10793.6397370214 20133.6733576563 19425.9604417093 479862.585611509 19112.6430839071 15540.5349209849 8867.5762168877 13583.6411853739 13432.6039289981 4922.1923907622 8813.70728419092 5347.53710647251 5693.39769710593 5449.92465658456 4781.88506146158 2420.35796398459 2791.08664885065 2702.85308607757 2493.82273051938 1194.98531761855 1006.8135972366 606.911454553949 74.3820038491121 0 86.8396574160475 18097 122215 97 4274.44753358853 5307.90662742597 4935.18351352117 3119.49129326969 11611.3510324527 14095.5344188625 9918.15959146086 19498.1294704868 21241.4431998128 558670.682919329 18099.8700970861 14869.4426836239 6893.63212499798 15075.8011792354 16396.1387892898 4066.71956237885 10729.0147782499 3966.8256130542 5783.35087392538 4115.00935321863 5114.85699620958 2918.07714853199 3372.94523619512 2316.45441407526 3035.91856265057 1210.84975096393 1098.43172213147 303.601193384936 60.6501349904576 0 93.5473170924789 18295 118342 98 4304.7050973719 5191.15277346728 5205.42022126829 2812.55736758411 11117.4752875966 12034.7639803192 12161.7815001454 21709.7018895941 18334.6065092513 504531.432268381 22194.3436386727 13761.6086683764 6102.0403249611 13251.6472581449 9389.23713741879 4725.26113580955 8367.62540276945 4828.9493952458 5546.74033055885 8225.17809334367 4974.56701404863 2639.32584453641 2415.21754341192 2656.09022614371 3391.15235640559 1085.72049868299 576.854522701187 282.437446638997 49.6854070484609 0 86.8570518130654 18386 119987 99 3748.73657304465 4828.30070889541 4711.21770941576 3027.79954719015 11272.1710395446 11703.6842915694 10519.4443084711 21949.6669453736 21851.5297786359 526166.905532312 20426.4346611285 12505.0104226363 6922.78518987492 13225.5221651646 16063.2006885874 4239.50895533885 11196.7068398946 4395.82729454926 5594.25488448466 4706.57623669593 4547.05817189656 2295.56061444683 2642.31269735125 2176.40216498704 3610.8889718583 1564.69061632746 689.082493049102 800.850714279333 58.4665476190477 0 84.1123238613035 18085 121554 100 3195.0922585096 3245.63904188682 5037.07146681984 2081.53339618307 9929.52297655691 13627.4002268977 12002.4939194915 20143.1363322565 18791.2473587306 505193.495234126 21813.5285211495 15569.5132492831 6644.04481363157 13898.1372594095 14926.4527903194 4703.62750817263 8923.71993506098 5181.07758231452 5366.75509734438 5750.45387938071 5336.82741764754 2823.61928887381 3292.39966560988 2840.36768875128 3094.26841723824 1319.08239559541 1010.60156574398 214.957819040981 41.1518820861678 0 82.1754293068774 18077 118796 Average (AVG) ping-pong signature and standard deviation (DEV) per [nt] 5' overlap (last 3 columns refer to avg. ppZScore, avg. ppSequeces and avg. ppReads incl. standard deviation). 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 ppZScore ppSequences ppReads AVG 4013.93392559549 5093.35754927986 5035.65943930672 2850.5727905397 10855.3304829143 12173.6927806916 11560.5026848323 20827.1382691847 19516.2842922923 522670.739620498 21006.6433464389 13992.2055825729 6845.85555159086 14185.5068623838 13378.235518315 4532.4935520871 10101.5094663061 4482.41401189142 5271.41081496453 4825.57908582599 4926.34203848931 2545.99342160931 2669.68912949139 2556.00065257627 3154.19605178099 1245.5361151929 937.144661078594 321.635705503052 50.3823260739763 0 86.9436663955859 18243.48 121796.16 DEV 583.684525947654 1288.96557705847 2339.06228875176 376.19883551439 1037.3607135148 932.47709635737 1426.89407498189 1544.24328717769 1472.58121119227 26693.8652914122 2142.51667707773 1695.47708029536 655.999379978085 1452.89065090275 2199.38992948934 398.61310050455 1289.68092116698 405.677814074708 375.115479995149 967.179583687206 401.541051289532 265.777802088859 340.611052235899 266.896481194116 330.269600208211 158.554502328788 177.980356858699 207.125027141832 17.3933101264398 0 6.77804097078102 165.43908123536 3091.70341307183 # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # Ping-pong signatures for 100 pseudo-replicate datasets (1000000 reads each) based on POR-82_preproc.map (5874594 reads) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 ppZScore ppSequences ppReads 1 7015.70256985778 16082.8548302074 10553.0488680487 4292.1415663544 12227.6408071426 15525.5396051505 24274.3905056 27627.5512246907 32474.7795913147 842453.896087137 33107.9327967175 18555.893919588 16093.5056620701 34460.8044318878 20685.8306567761 7782.40128109608 19594.9171721782 9420.21963107302 7598.18192613381 16570.9404790163 8496.35665459083 3790.51217745492 4077.06947186969 3929.41473538889 3022.97736567908 1794.25174043883 1294.55789438718 385.761479109156 63.7049833405767 0 91.4318224787297 20191 138049 2 7506.41207177661 22142.5979759635 12888.1043002116 4999.46469742007 10204.2826903505 12769.1781463788 22314.3048131517 24329.7511945778 36886.8959853246 826763.807842785 29352.4271830336 18264.2074852374 14401.2543119215 30869.1992106351 27586.0671080105 8517.24035099717 23033.2056829421 8694.47203679108 7799.29287307914 28099.3115271287 8002.41733645657 3459.30543904947 4799.54124821128 4108.94817577648 3187.85180218071 2055.96235022436 1220.75630034009 432.572810058691 162.375575037939 0 87.2874130842863 20561 137424 3 5619.7813380781 16526.61644591 10971.5311998814 4290.43800621696 11095.8810155521 16830.030408969 25835.4827774962 25295.1828854826 33597.6762377228 740708.536092873 30994.9953193675 20699.3998731571 14473.6549721625 28514.6846575262 18001.0874074643 8388.21043598207 24119.9038318783 8525.00973196318 5364.54397524052 19058.6700148033 6752.79826886201 4831.82525322898 12606.9161552898 3496.59806133327 2625.40596661439 1585.13810907409 1749.97215082628 460.423887013097 183.882538347766 0 82.2674490856639 19883 136099 4 5283.97668203506 12209.2810522802 9315.33454624379 4535.28444288543 11120.4725904688 15213.9393838028 24177.8020302757 26026.5188964403 29353.558920602 837390.991956074 31836.3599735875 20328.2051530853 14702.97697872 34352.4462646295 27017.1428712356 8751.83795149449 22982.065754243 8720.40597459008 5743.23507026395 26157.4258252645 9465.09911775158 3383.5760698276 6732.36499589726 4098.55649837974 3025.8663252638 1826.11519547111 1708.13877518493 330.322196705493 116.889410728099 0 86.4628606256059 20245 133422 5 5902.58797441601 17183.3061576011 9639.79201116578 4957.13644269968 10244.4555861969 11355.4519940848 21242.8920087444 30163.4725411624 36117.1123958267 819526.789436409 33226.5366042348 22408.4588939183 15952.4808172281 32590.4555305204 22027.9675217714 8260.92046512338 22733.9592029261 7915.38329943402 9982.76197145952 25211.9208765156 6100.78968760301 4358.30917636145 4302.09389214872 3508.09801018284 3844.40186055669 1632.19165547418 1986.71340591833 332.905452652443 137.636918709692 0 82.4022673881709 20251 134133 6 6607.9782470297 18030.0849094411 9302.81718152746 4509.5416188727 10999.054898585 11792.085183702 19506.1878567288 23696.528687887 31813.8894547798 766584.307610304 33635.7528720699 17586.3551153836 13878.8386856705 29546.6333517588 15283.4686315579 7895.09015694265 26448.5049797997 8526.15256637114 7947.13167823606 25487.0801549775 8101.16246996657 4093.7011917945 4513.86203054628 4056.18357421415 3706.4292448488 2262.45380592726 1834.39623166425 403.003382408584 183.201520067291 0 84.2768637553681 20118 135676 7 6356.2927492923 16858.3237136206 13561.9914731132 3709.30303070212 12083.4354906325 12211.8145989825 23406.0428723967 27292.4648892398 33870.7744067356 848699.155980965 32586.8040839398 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7851.3694464198 21916.365305812 9878.06284772278 6371.38080179757 22548.0775776006 8442.51181445982 3984.12230081066 4995.18290857817 3545.01280615569 3522.65167277497 1121.73178262258 1342.43785020277 385.21680620431 180.808022915381 0 85.8040062007553 20020 134991 82 5140.49463611379 15792.4414970846 10482.4863622666 4230.46696174844 9916.56248676162 15361.7453665626 24628.0729835476 24936.4881967445 35856.0697407609 847551.220148124 29423.853889844 24526.575821129 12755.5311012968 28092.502936743 23153.1432345465 8141.40410254182 22146.8670101631 8067.12433210303 5468.74184451631 25944.218773194 8772.08755210163 3303.23400491089 8405.19662839965 3564.32013029397 3286.13828629484 1458.34760765257 1356.33703484404 613.605359161318 188.019435194092 0 88.8359693895119 20284 134803 83 4866.46119202081 16563.6666762297 11563.5399648729 4242.10448687102 10164.9332932913 12963.375338702 23596.2428769473 19974.5118693639 33521.4565800217 753265.456430976 29078.7493599837 17077.3698124361 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33331.0684274208 758324.464270235 33368.5127006412 19483.7518579085 15332.9833220539 29250.1444381958 18285.2512253375 7067.6172016752 21988.4381836576 7554.74298330391 6534.28718617539 30275.2362767732 7291.77191664617 6281.49239846812 5020.32389006806 3193.94812549835 2756.11542446272 1479.88255551129 1676.50222040125 446.831117957411 221.618218607088 0 75.4497114227791 20740 142029 86 5156.27312787854 14273.3840570769 11005.6751824507 4528.99050689858 8421.09569494593 14849.4044904904 22568.2360159425 28521.4278673953 36853.7336105705 767575.631241965 34972.9484071994 17730.9222672409 14493.049883596 28626.811825539 15053.414660566 7287.5687509924 23053.8663558546 6654.19068457782 6693.33267308341 22808.4112862593 7517.61553712845 4873.97286833263 5898.86887485021 3035.99460109724 3065.29709737975 1821.74711611584 1504.14446365703 441.646317707591 179.539311943895 0 76.6424430930712 20440 138102 87 5533.00283408155 15121.2318654661 12385.3281022976 4697.2998012113 10686.3206090013 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12092.6472893317 4695.55889649237 11485.8079400143 12076.5221311335 20022.8007179541 25195.3044145147 31711.9673965126 786177.124475278 29026.6309690713 20178.319332042 15345.8960226453 33703.4549769943 21628.1955841675 7741.93184451777 24088.7531493282 7830.34681639861 9397.11577061688 22353.4586941323 6828.06377892085 4286.83296444113 5117.36022105413 3748.20960096483 3889.1208323265 1726.11632340548 1474.84240907473 366.334983083799 77.0290884912511 0 89.8691420096094 20402 136089 90 5780.24592036768 16636.7506639394 10423.3043117744 4833.18162226108 11435.2623796489 11377.9200425033 19774.8958541273 23943.7747976512 27874.0353866027 833391.210101564 31254.1700464507 20998.7595474562 12919.9399347632 33050.5562115035 18274.1231734084 7881.67644017619 21983.4367261926 7186.04250109437 8274.32837899889 17577.3417737623 7797.45204078479 2939.83771264943 3920.41388867463 3420.09317406875 3471.50193630819 1753.49533251688 1276.15718618665 508.536817575892 76.5759327408672 0 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1411.91234253111 417.985489966884 135.685153909205 0 90.6600834375061 20255 130727 93 5225.38893463584 18315.9407447372 8346.09356096542 5086.55638914736 11139.826342737 10502.5068701775 20571.7450669178 26553.888844143 32541.4061927034 824352.029619515 34855.4376920396 20096.3761385557 14575.4659902322 30833.3981337298 16920.0848565115 8943.90805698707 21786.5170388195 8296.89609833875 7036.62118333876 22366.1227802333 6710.78818179904 3832.70116254762 4240.61713762415 3322.92289025538 3548.06591333133 2264.27146193918 1483.29219466733 408.194051195757 121.672459867871 0 88.0686851080251 20257 141720 94 6078.84128688442 13042.5740864994 9241.24909100601 3911.87672236446 13319.2115794329 13371.557022694 16604.6376464926 24298.8276666484 33031.3391833497 819400.485953814 30779.8681359914 18231.4935645439 14683.8584149956 30811.0484216104 17103.9434102672 8530.41817819423 24151.540732593 8073.72300153395 8912.45529533091 23359.781525751 7248.90105047843 3894.74750800789 5229.56257130769 3715.28745859336 3973.2164591999 1591.06300621032 1586.69252237704 445.812076880585 160.202236635659 0 93.5791688104727 19925 133121 95 5483.37791422808 13457.7717619037 8018.35961265148 4223.49485965807 10681.7084586332 13717.5419435247 23134.8799238418 30216.6615692485 32545.7677253948 795784.404556358 32803.0873981658 17634.2384728935 14764.9352383695 33234.2561659674 27279.1076948398 10483.1403583656 22353.7028318147 8067.06694423916 7824.66028597881 25629.1573610811 8003.42404555676 4249.57598985332 3911.50132213049 3351.60950496434 3276.04865209378 1985.25540159731 996.096997386353 432.47518542892 84.75 0 79.7003529657955 20636 140388 96 4269.25781643859 15286.8473039405 10043.5069372296 4598.97085220692 10504.900142997 14472.6426138331 22602.1571429519 23832.7793948868 29803.7849125814 803535.05052977 34014.5780445834 17213.4391421189 13102.842749819 29476.4829549838 21818.5455308292 10154.1051849621 21743.8595919215 7708.14723097953 6252.75443675584 27811.7910938678 7084.41769998604 4883.82852250474 4486.75302879878 4069.17308969773 3656.05565373474 1967.38773015127 1182.29676302512 451.707975425834 135.95622170182 0 87.6586005033784 20216 132469 97 6415.85473038724 16137.6217139794 8507.75273495151 5088.05668520627 7928.40251370516 10868.1926805449 20680.3665909954 25259.0271629559 33135.9581011793 778797.205133796 31968.4542927446 18657.7245687486 13474.2848550888 30005.0163675422 14625.7591990972 8313.44437380985 24545.1073066361 7300.21467718109 5927.10238975371 22164.6224526859 7266.85391666914 4759.37397856755 4383.29105306813 2631.87606656745 2689.14154360299 1580.59890837992 1524.10760019318 440.74971159337 92.835151147113 0 83.8476615459509 19710 126801 98 4776.02458888051 15532.4886832975 10861.0983612286 4135.09277353095 13016.9724653418 15726.1398686458 20162.3461822718 24499.5683842689 31394.3536406324 899576.15749425 31916.9239512016 20226.9130534714 13371.9133142087 31479.2998662613 29481.2234917385 8466.83000227438 23040.9671756803 6822.71940704708 6568.63829188356 11860.1664283889 7203.8051494988 3933.58472830513 4379.18238198778 2681.14590871518 2638.80846672468 1686.16753398349 1416.93906968259 339.680153144838 145.329832326452 0 96.0147126525333 20213 141070 99 5084.88162343717 15000.4839783235 12874.0349622328 4792.3547987564 10491.6075078091 13424.2955867679 22967.5925422892 24726.5821309227 33106.0613078025 803002.426498036 32415.2946284943 19652.7090224421 13590.7780349292 26588.2880552629 24306.539664798 8073.66052285121 20843.8650296964 8900.95247426461 6179.55506575052 21043.7577776855 8247.96863688094 3846.64242970827 4025.56791715003 3092.10516510858 3074.84515873939 1481.40934264006 1762.34353980311 359.225827743129 219.452689775934 0 91.0117940760155 20524 141243 100 4783.87480173563 15227.7101951165 8872.23585219674 4561.01222226074 10995.5282645269 15141.9793312419 18567.8486413948 24042.477555112 33574.2947060725 747465.522604084 28692.7573438034 22676.1942353143 16583.0221602228 31124.1287201174 20537.9778520106 9799.68849650512 22574.7210644344 8791.65973410969 6639.5072819185 19047.3248172248 8307.83610695998 3916.83168200447 6047.29247314896 3355.25063341771 2962.70584006166 1687.45096258527 1500.4692172929 316.198112771866 178.303089597554 0 85.6428389573763 20441 143025 Average (AVG) ping-pong signature and standard deviation (DEV) per [nt] 5' overlap (last 3 columns refer to avg. ppZScore, avg. ppSequeces and avg. ppReads incl. standard deviation). 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 ppZScore ppSequences ppReads AVG 5608.0101340459 16124.5880143302 9837.82602277062 4735.00174567699 10836.6403427673 13407.0031706803 21846.1875680927 26561.4201958969 32916.9811804158 814542.546466749 31887.5050031931 19295.8144170981 14196.8546740232 30809.8527547804 19967.5424272295 8067.41557930936 22583.0460765957 8208.60661544321 6894.09835030951 23214.0519152495 7814.68459868286 4057.11461622243 4933.48769068648 3478.2880817403 3411.29685194816 1743.49311266268 1444.0438875408 421.543335264664 133.830525280473 0 87.2653679214451 20278.53 137009.47 DEV 873.695719594356 2310.73256697359 1344.60901959992 542.618377282283 1054.50672229548 1445.15511865824 2684.25920733145 3204.35208110321 2055.91673548724 34796.5751375907 2255.63396922466 2222.66997663429 1108.87131411408 2033.1342698238 4146.31322558809 737.361590977729 1684.05278227053 728.80415144772 1169.67827315718 4188.30942004449 827.00638548569 626.437809307639 1515.80203790929 409.422753217395 419.546015618915 295.169731305354 261.944342682947 70.680993928237 47.3693607794373 0 5.43740625327009 230.973827738123 3972.22018134695 # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # Testing for significantly different ping-pong signatures (Mann-Whitney U-test) + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + group1 (sRNA-ACR-140_preproc.map, sRNA-ACR-145_preproc.map, sRNA-ACR-150_preproc.map, sRNA-ACR-173_preproc.map, sRNA-ACR-178_preproc.map) vs. group2 (POR-73_preproc.map, POR-79_preproc.map, POR-82_preproc.map) -> Scores for 10nt 5' overlaps are different with significance level: p<0.0001 (Z=22.24). Sorted scores and ranks for group1 2718012.92158017 800 2711872.00120478 799 2700450.78450985 798 2666026.78371462 797 2664187.63402009 796 2657278.63952419 795 2629922.00512958 794 2625031.71390824 793 2616420.27938062 792 2611826.91345613 791 2597616.70489144 790 2596030.90962769 789 2593979.73824922 788 2589857.02973306 787 2585500.09953347 786 2573842.98411916 785 2565329.44806353 784 2558412.16911938 783 2554381.27985533 782 2552153.86363848 781 2551440.69804121 780 2547920.82870593 779 2547435.67322693 778 2545490.73768012 777 2540527.96549249 776 2533797.06792466 775 2532955.11806628 774 2530132.99793942 773 2528973.10129213 772 2528011.72246997 771 2527754.04787591 770 2526601.78387263 769 2525221.6572897 768 2517035.92901867 767 2516224.09939717 766 2515962.43522174 765 2512507.10396986 764 2509643.78223652 763 2504325.27548477 762 2503501.69006116 761 2499980.29086188 760 2499498.6477084 759 2496409.90429514 758 2495812.75265748 757 2493121.0221561 756 2492789.98530953 755 2489629.23508029 754 2488052.67639693 753 2485486.96516912 752 2482167.9534757 751 2480418.61482963 750 2479585.24750417 749 2476675.90966676 748 2473865.14037277 747 2473079.45221646 746 2470850.64362629 745 2468772.36445819 744 2465904.83880813 743 2462808.40399934 742 2462218.61332303 741 2462020.89819961 740 2458086.58393617 739 2456780.88553867 738 2456465.6074273 737 2452439.17315246 736 2452108.89752804 735 2451654.14274299 734 2450048.73916193 733 2449309.59885454 732 2444694.29907236 731 2435219.82597616 730 2434078.50826317 729 2432941.75380614 728 2431828.42325671 727 2431660.53718126 726 2429904.48844817 725 2429687.85993403 724 2425121.7354107 723 2424814.87849021 722 2421862.49145208 721 2417721.22936332 720 2416977.78698048 719 2414130.62005845 718 2413575.59036878 717 2412161.9695326 716 2410185.06618708 715 2408726.53098396 714 2404400.69084676 713 2397741.06365725 712 2394277.70748149 711 2384821.99357504 710 2384482.80418737 709 2374440.73586597 708 2368321.22212545 707 2362531.95607692 706 2356634.86358691 705 2355923.42618883 704 2331199.25646647 703 2309637.35854332 702 2231197.18469668 701 2124353.40563912 700 2091024.49265777 699 2071800.48548547 698 2049708.17824771 697 2048221.41424267 696 2047374.71443836 695 2046296.20201891 694 2044466.93171139 693 2041795.37887878 692 2035462.64346615 691 2032918.07748992 690 2030418.97591934 689 2025414.92887117 688 2022161.21204935 687 2020868.55182898 686 2019193.61960649 685 2017877.19050092 684 2016899.12940475 683 2010251.01890838 682 2010133.36892527 681 2009549.48181062 680 2007849.17810051 679 2007838.73498448 678 2006733.20101842 677 2006709.67037508 676 2006466.67552895 675 2004397.8587212 674 2002510.02485967 673 2002463.07829904 672 2001814.052813 671 2001484.22815233 670 1997332.35660506 669 1996088.71845102 668 1991815.94506641 667 1991196.42428242 666 1991120.16730371 665 1990148.23166734 664 1987477.33610324 663 1986024.08403468 662 1985788.44060906 661 1985100.71442332 660 1984885.36614009 659 1984458.43053603 658 1983725.04883774 657 1980262.27355856 656 1980025.07490169 655 1976216.09559116 654 1974879.68273086 653 1974647.6545831 652 1974600.35430828 651 1972598.84814869 650 1972474.25154582 649 1971602.44935691 648 1971402.31597152 647 1971150.0326786 646 1970503.23203977 645 1969873.0590812 644 1966967.86149123 643 1966885.17850012 642 1965644.19859408 641 1965141.69841778 640 1964473.79427081 639 1964298.03456745 638 1963917.4404264 637 1963173.71526044 636 1961678.59964549 635 1959082.26318246 634 1958307.99229227 633 1956915.34967558 632 1956806.08264914 631 1956552.36619943 630 1955548.92817515 629 1954130.2924845 628 1953163.08308116 627 1953146.68169589 626 1952826.82246212 625 1952280.17687382 624 1951873.34347906 623 1951735.54445473 622 1950967.25344081 621 1950934.29422721 620 1949626.96184045 619 1949604.92207054 618 1948974.97946602 617 1948947.7548323 616 1948563.88201976 615 1947435.21097159 614 1945666.05304465 613 1943583.0674368 612 1942218.38029767 611 1941864.91855481 610 1937191.28750794 609 1936925.24522891 608 1936603.63566419 607 1936598.29479569 606 1936325.40872636 605 1934985.55227891 604 1934251.12013897 603 1934095.92812271 602 1933805.41193542 601 1932931.56812754 600 1932159.90950279 599 1931416.32386188 598 1930839.82518209 597 1930576.65949162 596 1929982.10807026 595 1929957.80016108 594 1929496.3627776 593 1929304.54005679 592 1928719.24409613 591 1927697.86040582 590 1927199.54720916 589 1926809.73788912 588 1924000.60434816 587 1923638.31558213 586 1923511.6680359 585 1923194.85488216 584 1922551.68608858 583 1922418.29302213 582 1920757.8555269 581 1920386.8401121 580 1920294.06351706 579 1920093.73379748 578 1919798.36909113 577 1918049.58155247 576 1917907.15215598 575 1917475.79754724 574 1917053.84167195 573 1916321.1024474 572 1915833.66891053 571 1915373.83741882 570 1914987.44297754 569 1914558.72183038 568 1914417.03662111 567 1914371.7090491 566 1914155.09872839 565 1911860.35019929 564 1911218.41264886 563 1910685.76329453 562 1910672.0363633 561 1909998.95200801 560 1909382.05872252 559 1908441.52580347 558 1907913.57851802 557 1907716.62309575 556 1907264.90503325 555 1907237.12208635 554 1905741.41701759 553 1904891.25601254 552 1904459.14242771 551 1904205.11831891 550 1903433.92114615 549 1901609.22096614 548 1901408.91630387 547 1901385.43007856 546 1901110.14077476 545 1899052.16256919 544 1898818.50417811 543 1898738.69536681 542 1898405.37270845 541 1897850.58374413 540 1897334.67111639 539 1896998.66073383 538 1896428.53871622 537 1894567.19877375 536 1892998.10348931 535 1892900.53412508 534 1892202.39988452 533 1891960.86772838 532 1891954.97919104 531 1891612.52137827 530 1889903.41184913 529 1888989.43427971 528 1887944.88436003 527 1887527.71353472 526 1886448.55035383 525 1885026.73110435 524 1883689.29194707 523 1882895.32581887 522 1881730.91757384 521 1881009.19008196 520 1878166.79538465 519 1877281.77985694 518 1874325.3149603 517 1872275.69592727 516 1872111.94992499 515 1870493.00260767 514 1869917.93380659 513 1863126.28731867 512 1861390.55573706 511 1859484.34203898 510 1857908.61917477 509 1857519.70288874 508 1855696.011626 507 1851663.68242281 506 1851585.61353275 505 1849480.40316823 504 1843184.84031254 503 1829340.20794868 502 1817017.84250765 501 1816605.52851059 500 1815836.90816817 499 1797400.22689009 498 1796689.03634089 497 1796541.97578455 496 1796413.80888713 495 1792928.31318977 494 1791446.12354921 493 1791202.8288755 492 1789049.23790039 491 1788025.76644439 490 1783267.39310619 489 1779067.47281053 488 1776658.46340451 487 1775514.66764349 486 1774209.68973882 485 1773925.31381912 484 1773554.9261846 483 1772173.48845505 482 1770302.16742649 481 1759802.15145336 480 1759725.77276541 479 1758623.87683101 478 1755688.11030097 477 1754697.8754951 476 1748034.69010684 475 1747564.67976699 474 1746487.17058068 473 1746010.49938675 472 1744193.31188697 471 1741898.95706128 470 1741107.43392722 469 1741054.54559495 468 1739448.17319858 467 1736563.23763207 466 1735876.23791214 465 1734724.60491711 464 1734396.82766259 463 1733632.47467786 462 1732928.6230869 461 1731739.0390359 460 1724104.83752902 459 1721877.73053121 458 1721864.44869584 457 1720452.9271438 456 1719386.32803173 455 1718530.35342487 454 1717271.20116031 453 1716862.11753395 452 1714353.31815789 451 1711643.38879883 450 1709054.67192888 449 1708994.88365559 448 1708504.75225693 447 1695658.46231408 446 1695460.60466391 445 1695295.92657693 444 1694311.04985389 443 1692877.34788892 442 1691685.66228569 441 1691409.1432145 440 1691050.04273851 439 1689340.91535386 438 1682853.87501236 437 1681189.63892381 436 1680997.77648587 435 1679450.87962933 434 1677161.58660727 433 1675226.14560874 432 1668996.55351844 431 1668660.37140742 430 1667950.5558992 429 1665645.0370988 428 1665107.95613385 427 1664873.64744647 426 1664769.17084428 425 1664455.03065334 424 1663390.64837357 423 1662846.47657585 422 1662168.31562731 421 1661763.15673133 420 1661379.63299767 419 1654829.03101718 418 1653328.92281436 417 1650097.73635843 416 1646393.50103067 415 1643680.97527404 414 1640942.75363358 413 1637400.02222879 412 1634402.360245 411 1631304.5864046 410 1629588.91184397 409 1627945.78517661 408 1624772.84202517 407 1608063.93442791 406 1604391.494534 405 1580581.73885048 404 1578974.52754768 403 1543416.64375057 402 1540351.3626459 401 1348983.94793377 400 1348063.80400189 399 1328603.94262366 397 1318756.76373658 392 1311915.78119094 388 1310906.93599424 387 1310627.80763757 386 1305109.42200111 382 1303929.86695519 380 1302307.37735556 379 1301480.82514943 378 1294030.00621827 376 1291832.77596273 374 1290219.09929198 371 1288161.40337488 369 1288030.02567487 368 1287558.04890826 367 1285007.7922412 365 1283784.63942048 364 1283652.01693565 363 1283208.76628788 362 1282370.56756529 361 1279131.37994297 360 1277964.63338167 358 1276568.7142163 357 1273858.38821497 354 1273823.4462105 353 1273533.39637548 352 1267333.83335907 345 1267230.37069947 344 1263417.65198809 340 1262571.80842022 338 1261197.18133056 336 1261143.62678129 335 1260256.79578183 334 1258472.15527354 331 1258434.03031671 330 1257878.59523427 329 1256361.76484403 327 1255167.13988888 323 1255034.8802227 322 1254076.23518327 321 1253044.22633448 320 1249710.91067157 319 1246294.7137385 316 1245412.97106249 312 1243628.55282382 309 1243093.07599364 308 1243061.71767833 307 1241252.37526285 306 1238975.11767333 304 1237940.18928292 302 1234455.54445882 298 1232417.00482647 296 1231845.40113572 295 1231728.05567747 293 1231520.17168065 292 1230485.82287698 291 1230126.29759352 290 1229659.52963088 289 1228634.64599947 288 1227757.253508 286 1226843.88135599 283 1225951.2348688 281 1224266.36421321 280 1223774.83691844 279 1223616.70480261 278 1221792.67547877 275 1220898.12207504 272 1219474.98875254 270 1218870.784851 269 1218430.03518791 268 1218379.22615414 267 1218198.56230993 265 1217934.27686708 264 1212335.8488061 259 1211091.04564908 255 1208094.67618371 251 1207561.47350967 250 1207385.40961268 248 1207370.25403079 247 1206529.83572554 245 1204419.31156813 243 1202079.49443779 239 1201313.56982682 238 1198692.05564049 236 1197534.89128763 234 1194920.39714494 232 1193886.09900475 231 1191228.58164425 228 1187853.49400207 226 1183263.45620337 222 1181400.48913099 219 1177613.54030733 217 1167434.78553817 212 1164363.96654326 211 1163734.50505135 210 1160539.58783865 207 1160163.4731619 206 1158168.66720657 204 Sorted scores and ranks for group2 1330158.3479775 398 1326672.51182689 396 1326294.40848943 395 1324655.64368469 394 1322461.78950314 393 1318418.87020406 391 1315360.19277171 390 1315121.45609755 389 1310409.08413898 385 1307646.16830954 384 1307627.9107723 383 1304767.572857 381 1299580.96526612 377 1293026.26663547 375 1291562.43989626 373 1290716.48202903 372 1290169.1750711 370 1285653.30190346 366 1278158.64233018 359 1276564.49495672 356 1276268.11421399 355 1272904.25325753 351 1271422.88370315 350 1270609.94100026 349 1269797.54783772 348 1269539.03143562 347 1268857.50207728 346 1265757.36544814 343 1264111.97530244 342 1263747.52973019 341 1263368.97545653 339 1261787.56876517 337 1260067.99018791 333 1259709.37079625 332 1256632.53498621 328 1255776.76179298 326 1255758.39454478 325 1255370.04189112 324 1248837.7827997 318 1247566.58645232 317 1245933.09232139 315 1245536.84665416 314 1245426.1085917 313 1244507.29201189 311 1244327.7036561 310 1240905.70340309 305 1237979.98527733 303 1236415.57913675 301 1236196.81815441 300 1235362.76699869 299 1233968.28621749 297 1231776.90211907 294 1228354.53450489 287 1227171.36123622 285 1227163.39191517 284 1226376.49039551 282 1223279.00069885 277 1222709.65705258 276 1221337.86621069 274 1221083.01028862 273 1220274.67726924 271 1218255.06143867 266 1215830.10117762 263 1215820.05624256 262 1215499.5647818 261 1214999.69879073 260 1212301.24416313 258 1212074.70402719 257 1211807.94425707 256 1209827.27821758 254 1209234.5345537 253 1208647.657025 252 1207517.42127864 249 1207031.41197589 246 1204429.7443567 244 1203472.30955947 242 1202745.50833386 241 1202297.58591811 240 1198900.16046901 237 1198375.67401087 235 1196752.87480503 233 1192281.15445936 230 1191773.40671532 229 1190237.54758351 227 1185721.18709895 225 1184044.06143811 224 1183727.09229821 223 1182738.07322506 221 1181880.48523824 220 1179935.57660111 218 1176069.15725504 216 1171239.89276537 215 1169107.83871725 214 1167756.98657573 213 1161207.65356952 209 1160713.04979705 208 1158705.64063771 205 1134884.24244514 203 1132782.59084009 202 1098389.03680631 201 899576.15749425 200 886317.540274934 199 878795.012717576 198 870323.454914473 197 867172.383983281 196 865094.657832686 195 862364.421257436 194 861929.405982098 193 861795.926907626 192 860956.904688139 191 859963.182207392 190 857219.562438967 189 851118.653128136 188 850224.641377708 187 848699.155980965 186 847551.220148124 185 847311.881439717 184 846794.547750118 183 845184.011257283 182 844863.650335081 181 844630.914066645 180 844148.98750479 179 842453.896087137 178 840473.465428238 177 839945.715693101 176 837390.991956074 175 835896.843030137 174 834990.509420601 173 834261.431923597 172 833670.355392054 171 833515.935030365 170 833391.210101564 169 833152.516097438 168 832326.198795485 167 831582.893433622 166 830865.02481632 165 829898.295046213 164 829795.638560562 163 828918.055353017 162 828810.721071803 161 828769.455946857 160 826763.807842785 159 824352.029619515 158 823682.565557433 157 822584.961569516 156 821476.18941436 155 821347.830425939 154 821042.996079151 153 819526.789436409 152 819400.485953814 151 818719.518593357 150 817839.395529089 149 816789.307704373 148 813970.855584668 147 813262.752224486 146 811757.675391589 145 810952.589646429 144 810434.188430538 143 810295.17365383 142 808465.399831234 141 808063.268571446 140 807819.302075511 139 805894.928718018 138 805646.141821052 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