# go_term

go_id: GO:0019682
term: glyceraldehyde-3-phosphate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving glyceraldehyde-3-phosphate, an important intermediate in glycolysis.


go_id: GO:0019683
term: glyceraldehyde-3-phosphate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of glyceraldehyde-3-phosphate, an important intermediate in glycolysis.


go_id: GO:0019684
term: photosynthesis, light reaction
ontology: BP
definition:
The light reactions of photosynthesis, which take place in photosystems II and I. Light energy is harvested and used to power the transfer of electrons among a series of electron donors and acceptors. The final electron acceptor is NADP+, which is reduced to NADPH. NADPH generated from light reactions is used in sugar synthesis in dark reactions. Light reactions also generate a proton motive force across the thylakoid membrane, and the proton gradient is used to synthesize ATP. There are two chemical reactions involved in the light reactions: water oxidation in photosystem II, and NADP reduction in photosystem I.


go_id: GO:0019685
term: photosynthesis, dark reaction
ontology: BP
definition:
A complex cycle of enzyme-mediated reactions which catalyzes the reduction of carbon dioxide to sugar. As well as carbon dioxide the cycle requires reducing power in the form of reduced nicotinamide adenine dinucleotide phosphate (NADP) and chemical energy in the form of adenosine triphosphate (ATP). The reduced NADP (NADPH) and ATP are produced by the 'light' reactions.


go_id: GO:0019686
term: purine nucleoside interconversion
ontology: BP
definition:
The chemical reactions and pathways by which a purine nucleoside is synthesized from another purine nucleoside.


go_id: GO:0019687
term: pyruvate biosynthetic process from acetate
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of pyruvate from other compounds, including acetate.


go_id: GO:0019688
term: purine deoxyribonucleoside interconversion
ontology: BP
definition:
The chemical reactions and pathways by which a purine deoxyribonucleoside is synthesized from another purine deoxyribonucleoside.


go_id: GO:0019689
term: pyrimidine nucleoside interconversion
ontology: BP
definition:
The chemical reactions and pathways by which a pyrimidine nucleoside is synthesized from another pyrimidine nucleoside.


go_id: GO:0019690
term: pyrimidine deoxyribonucleoside interconversion
ontology: BP
definition:
The chemical reactions and pathways by which a pyrimidine deoxyribonucleoside is synthesized from another deoxyribopyrimidine nucleoside.


go_id: GO:0019692
term: deoxyribose phosphate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose.


go_id: GO:0019694
term: alkanesulfonate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving alkanesulfonates, the anion of alkanesulfonic acids, sulfonic acid derivatives containing an aliphatic hydrocarbon group.


go_id: GO:0019695
term: choline metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.


go_id: GO:0019696
term: toluene oxidation via toluene-cis-1,2-dihydrodiol
ontology: BP
definition:
The degradation of toluene to form pyruvate and acetaldehyde; the first step in the pathway is the oxidation of toluene to form toluene-cis-1,2-dihydrodiol.


go_id: GO:0019697
term: L-xylitol catabolic process to xylulose 5-phosphate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of L-xylitol to form xylulose 5-phosphate. L-xylitol is converted into L-xylulose, which is then phosphorylated to L-xylulose-5-phosphate. This is converted to D-xylulose-5-phosphate via the intermediate L-ribulose-5-phosphate.


go_id: GO:0019698
term: D-galacturonate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of D-galacturonate, the D-enantiomer of galacturonate, the anion of galacturonic acid.


go_id: GO:0019700
term: organic phosphonate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of phosphonates, any organic compound containing one or more C-PO(OH)2 or C-PO(OR)2 (with R=alkyl, aryl) groups. Catabolism of phosphonic acid itself, an inorganic compound without the biochemically relevant C-P bond, is not included.


go_id: GO:0019701
term: peptidyl-arginine N5-methylation
ontology: BP
definition:
The methylation of peptidyl-arginine on the internal nitrogen-5 (N5) atom (also called delta-nitrogen) to form peptidyl-N5-methyl-L-arginine.


go_id: GO:0019702
term: protein-arginine N5-methyltransferase activity
ontology: MF
definition:
Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the delta-nitrogen atom of peptidyl-arginine residues. The reaction is S-adenosyl-L-methionine + [protein]-L-arginine = S-adenosyl-L-homocysteine + [protein]-N5-methyl-L-arginine.


go_id: GO:0019705
term: protein-cysteine S-myristoyltransferase activity
ontology: MF
definition:
Catalysis of the transfer of a myristoyl (systematic name, tetradecanoyl) group to a sulfur atom on a cysteine residue of a protein molecule in the reaction: tetradecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-tetradecanoyl-L-cysteinyl-[protein].


go_id: GO:0019706
term: protein-cysteine S-palmitoyltransferase activity
ontology: MF
definition:
Catalysis of the transfer of a palmitoyl (systematic name, hexadecanoyl) group to a sulfur atom on the cysteine of a protein molecule, in the reaction hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein].


go_id: GO:0019708
term: peptidyl-glycine cholesteryl ester biosynthesis from peptidyl-glycine
ontology: BP
definition:
The synthesis of peptidyl-glycine cholest-5-en-3-beta-ol ester at the carboxy-terminus of autolytically cleaved proteins.


go_id: GO:0019709
ontology: BP
term:
iron incorporation into iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide

definition:
The incorporation of iron into a nickel-iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide, found in carbon monoxide dehydrogenase.


go_id: GO:0019710
term: peptidyl-asparagine methylation
ontology: BP
definition:
The methylation of peptidyl-asparagine to form peptidyl-N4-methyl-L-asparagine or peptidyl-N4,N4-dimethyl-L-asparagine.


go_id: GO:0019711
term: peptidyl-beta-carboxyaspartic acid biosynthetic process from peptidyl-aspartic acid
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of peptidyl-beta-carboxyaspartic acid from other compounds, including peptidyl-aspartic acid.


go_id: GO:0019715
term: peptidyl-aspartic acid hydroxylation to form L-erythro-beta-hydroxyaspartic acid
ontology: BP
definition:
The hydroxylation of peptidyl-aspartic acid to form peptidyl-L-erythro-beta-hydroxyaspartic acid; catalyzed by peptide-aspartate beta-dioxygenase (EC:1.14.11.16).


go_id: GO:0019716
term: N-terminal peptidyl-alanine monomethylation
ontology: BP
definition:
The monomethylation of the N-terminal alanine of proteins to form the derivative peptidyl-N-methyl-L-alanine.


go_id: GO:0019720
term: Mo-molybdopterin cofactor metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.


go_id: GO:0019722
term: calcium-mediated signaling
ontology: BP
definition:
Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions.


go_id: GO:0019724
term: B cell mediated immunity
ontology: BP
definition:
Any process involved with the carrying out of an immune response by a B cell, through, for instance, the production of antibodies or cytokines, or antigen presentation to T cells.


go_id: GO:0019730
term: antimicrobial humoral response
ontology: BP
definition:
An immune response against microbes mediated through a body fluid. Examples of this process are seen in the antimicrobial humoral response of Drosophila melanogaster and Mus musculus.


go_id: GO:0019731
term: antibacterial humoral response
ontology: BP
definition:
An immune response against bacteria mediated through a body fluid. Examples of this process are the antibacterial humoral responses in Mus musculus and Drosophila melanogaster.


go_id: GO:0019732
term: antifungal humoral response
ontology: BP
definition:
An immune response against a fungus mediated through a body fluid. An example of this process is the antifungal humoral response in Drosophila melanogaster.


go_id: GO:0019740
term: nitrogen utilization
ontology: BP
definition:
A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary nitrogen source, usually ammonia, and then activates genes to scavenge the last traces of the primary nitrogen source and to transport and metabolize alternative nitrogen sources. The utilization process begins when the cell or organism detects nitrogen levels, includes the activation of genes whose products detect, transport or metabolize nitrogen-containing substances, and ends when nitrogen is incorporated into the cell or organism's metabolism.


go_id: GO:0019741
term: pentacyclic triterpenoid catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of pentacyclic triterpenoid compounds, terpenoids with six isoprene units and 5 carbon rings.


go_id: GO:0019742
term: pentacyclic triterpenoid metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving pentacyclic triterpenoid compounds, terpenoids with six isoprene units and 5 carbon rings.


go_id: GO:0019743
term: hopanoid catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of hopanoids, pentacyclic sterol-like compounds based on the hopane nucleus.


go_id: GO:0019744
term: hopanoid metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving hopanoids, pentacyclic sterol-like compounds based on the hopane nucleus.


go_id: GO:0019745
term: pentacyclic triterpenoid biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of pentacyclic triterpenoid compounds, terpenoids with six isoprene units and 5 carbon rings.


go_id: GO:0019746
term: hopanoid biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of hopanoids, pentacyclic sterol-like compounds based on the hopane nucleus.


go_id: GO:0019747
term: regulation of isoprenoid metabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving isoprenoids.


go_id: GO:0019748
term: secondary metabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients.


go_id: GO:0019749
term: cytoskeleton-dependent cytoplasmic transport, nurse cell to oocyte
ontology: BP
definition:
The directed movement of substances along cytoskeletal elements, such as microfilaments or microtubules, from a nurse cell to an oocyte.


go_id: GO:0019750
term: chloroplast localization
ontology: BP
definition:
Any process in which a chloroplast is transported to, and/or maintained in, a specific location within the cell. A chloroplast is a chlorophyll-containing plastid found in cells of algae and higher plants.


go_id: GO:0019751
term: polyol metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms.


go_id: GO:0019752
term: carboxylic acid metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).


go_id: GO:0019755
term: one-carbon compound transport
ontology: BP
definition:
The directed movement of one-carbon compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0019756
term: cyanogenic glycoside biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of cyanogenic glycosides, any glycoside containing a cyano group that is released as hydrocyanic acid on acid hydrolysis; such compounds occur in the kernels of various fruits.


go_id: GO:0019757
term: glycosinolate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving glycosinolates, substituted thioglycosides found in rapeseed products and related cruciferae.


go_id: GO:0019758
term: glycosinolate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of glycosinolates, substituted thioglycosides found in rapeseed products and related cruciferae.


go_id: GO:0019759
term: glycosinolate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of glycosinolates, substituted thioglycosides found in rapeseed products and related cruciferae.


go_id: GO:0019760
term: glucosinolate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae. They are metabolized to a variety of toxic products which are most likely the cause of hepatocytic necrosis in animals and humans.


go_id: GO:0019761
term: glucosinolate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.


go_id: GO:0019762
term: glucosinolate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.


go_id: GO:0019763
term: immunoglobulin receptor activity
ontology: MF
definition:
Combining with the Fc region of an immunoglobulin protein and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


go_id: GO:0019766
term: IgA receptor activity
ontology: MF
definition:
Combining with an immunoglobulin of an IgA isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


go_id: GO:0019767
term: IgE receptor activity
ontology: MF
definition:
Combining with an immunoglobulin of the IgE isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


go_id: GO:0019768
term: high-affinity IgE receptor activity
ontology: MF
definition:
Combining with high affinity with an immunoglobulin of the IgE isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


go_id: GO:0019769
term: low-affinity IgE receptor activity
ontology: MF
definition:
Combining with low affinity with an immunoglobulin of the IgE isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


go_id: GO:0019770
term: IgG receptor activity
ontology: MF
definition:
Combining with an immunoglobulin of an IgG isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


go_id: GO:0019771
term: high-affinity IgG receptor activity
ontology: MF
definition:
Combining with high affinity with an immunoglobulin of an IgG isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


go_id: GO:0019772
term: low-affinity IgG receptor activity
ontology: MF
definition:
Combining with low affinity with an immunoglobulin of an IgG isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


go_id: GO:0019773
term: proteasome core complex, alpha-subunit complex
ontology: CC
definition:
The proteasome core subcomplex that constitutes the two outer rings of the proteasome core complex. An example of this component is found in Mus musculus.


go_id: GO:0019774
term: proteasome core complex, beta-subunit complex
ontology: CC
definition:
The proteasome core subcomplex that constitutes the two inner rings of the proteasome core complex. An example of this component is found in Mus musculus.


go_id: GO:0019775
term: FAT10 transferase activity
ontology: MF
definition:
Catalysis of the transfer of FAT10 from one protein to another via the reaction X-FAT10 + Y --> Y-FAT10 + X, where both X-FAT10 and Y-FAT10 are covalent linkages.


go_id: GO:0019776
term: Atg8 ligase activity
ontology: MF
definition:
Catalysis of the covalent attachment of the ubiquitin-like protein Atg8 to substrate molecules; phosphatidylethanolamine is a known substrate.


go_id: GO:0019777
term: Atg12 transferase activity
ontology: MF
definition:
Catalysis of the transfer of ATG12 from one protein to another via the reaction X-ATG12 + Y --> Y-ATG12 + X, where both X-ATG12 and Y-ATG12 are covalent linkages.


go_id: GO:0019778
term: Atg12 activating enzyme activity
ontology: MF
definition:
Catalysis of the activation of the small ubiquitin-related modifier APG12, through the formation of an ATP-dependent high-energy thiolester bond.


go_id: GO:0019779
term: Atg8 activating enzyme activity
ontology: MF
definition:
Catalysis of the activation of the small ubiquitin-related modifier APG8, through the formation of an ATP-dependent high-energy thiolester bond.


go_id: GO:0019780
term: FAT10 activating enzyme activity
ontology: MF
definition:
Catalysis of the activation of the small ubiquitin-related modifier FAT10, through the formation of an ATP-dependent high-energy thiolester bond.


go_id: GO:0019782
term: ISG15 activating enzyme activity
ontology: MF
definition:
Catalysis of the activation of the small ubiquitin-related modifier ISG15, through the formation of an ATP-dependent high-energy thiolester bond.


go_id: GO:0019783
term: ubiquitin-like protein peptidase activity
ontology: MF
definition:
An isopeptidase activity that cleaves ubiquitin or ubiquitin-like proteins (ULP; e.g. ATG8, ISG15, NEDD8, SUMO) from target proteins.


go_id: GO:0019785
term: ISG15-specific peptidase activity
ontology: MF
definition:
A thiol-dependent isopeptidase activity that cleaves ISG15 from a target protein to which it is conjugated.


go_id: GO:0019786
term: Atg8-specific peptidase activity
ontology: MF
definition:
A thiol-dependent isopeptidase activity that cleaves APG8 from a target protein to which it is conjugated.


go_id: GO:0019787
term: ubiquitin-like protein transferase activity
ontology: MF
definition:
Catalysis of the transfer of a ubiquitin-like from one protein to another via the reaction X-ULP + Y --> Y-ULP + X, where both X-ULP and Y-ULP are covalent linkages. ULP represents a ubiquitin-like protein.


go_id: GO:0019788
term: NEDD8 transferase activity
ontology: MF
definition:
Catalysis of the transfer of NEDD8 from one protein to another via the reaction X-NEDD8 + Y --> Y-NEDD8 + X, where both X-NEDD8 and Y-NEDD8 are covalent linkages.


go_id: GO:0019789
term: SUMO transferase activity
ontology: MF
definition:
Catalysis of the transfer of SUMO from one protein to another via the reaction X-SUMO + Y --> Y-SUMO + X, where both X-SUMO and Y-SUMO are covalent linkages.


go_id: GO:0019797
term: procollagen-proline 3-dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-3-hydroxy-L-proline + succinate + CO2.


go_id: GO:0019798
term: procollagen-proline dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-hydroxy-L-proline + succinate + CO2.


go_id: GO:0019799
term: tubulin N-acetyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: acetyl-CoA + (alpha-tubulin) L-lysine = CoA + (alpha-tubulin) N6-acetyl-L-lysine.


go_id: GO:0019800
term: peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan
ontology: BP
definition:
The formation of a cross-link between peptide chains mediated by a chondroitin 4-sulfate glycosaminoglycan that originates from a typical O-glycosidic link to serine of one chain; the other chain is esterified, via the alpha-carbon of its C-terminal Asp, to C-6 of an internal N-acetylgalactosamine of the glycosaminoglycan chain.


go_id: GO:0019801
term: cyclization of asparagine involved in intein-mediated protein splicing
ontology: BP
definition:
The cyclization of asparagine to yield an L-aspartimide (otherwise known as alpha-aminosuccinimide) residue at the C-terminus of an excised intein during protein splicing.


go_id: GO:0019802
term: cyclization of glutamine involved in intein-mediated protein splicing
ontology: BP
definition:
The cyclization of glutamine to yield an L-glutamimide residue at the C-terminus of an excised intein during protein splicing.


go_id: GO:0019805
term: quinolinate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid.


go_id: GO:0019806
term: bromide peroxidase activity
ontology: MF
definition:
Catalysis of the reaction: 2 R-H + 2 bromide + hydrogen peroxide = 2 R-Br + 2 H2O. Enzymes with this activity often accept other halide ions as substrates, including chloride and iodide.


go_id: GO:0019810
term: putrescine binding
ontology: MF
definition:
Binding to putrescine, 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine.


go_id: GO:0019811
term: cocaine binding
ontology: MF
definition:
Binding to cocaine (2-beta-carbomethoxy-3-beta-benzoxytropane), an alkaloid obtained from dried leaves of the South American shrub Erythroxylon coca or by chemical synthesis.


go_id: GO:0019812
term: type I site-specific deoxyribonuclease complex
ontology: CC
definition:
A multisubunit complex composed of two copies of a restriction (R) subunit, two copies of a methylation (M) subunit, and one copy of a specificity (S) subunit. This complex recognizes specific short DNA sequences (through the S subunit), and binds to them. If the recognition site is hemimethylated, the complex acts as a methyltransferase which modifies the recognition site, using S-adenosylmethionine as the methyl donor. Only the M and S subunits are required for this reaction. If the complex binds to an unmethylated recognition site, then the complex translocates the DNA bidirectionally in an ATP-dependent manner. When the translocation is stalled by impact with another complex or unusual DNA structure, the enzyme functions as an endonuclease and cleavage of the DNA will occur, hundreds or thousands of base pairs away from the recognition site. These DNA restriction systems are used by bacteria to defend against phage and other foreign DNA that may enter a cell.


go_id: GO:0019813
term: type III site-specific deoxyribonuclease complex
ontology: CC
definition:
A heterodimeric enzyme complex composed of two subunits, Res and Mod, that functions as an endonuclease and cleaves DNA. Cleavage will only occur when there are two un-methylated copies of a specific recognition site in an inverse orientation on the DNA. Cleavage occurs at a specific distance away from one of the recognition sites. The Mod subunit can act alone as a methyltansferase. DNA restriction systems such as this are used by bacteria to defend against phage and other foreign DNA that may enter a cell.


go_id: GO:0019814
term: immunoglobulin complex
ontology: CC
definition:
A protein complex that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains, held together by disulfide bonds and sometimes complexed with additional proteins. An immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.


go_id: GO:0019815
term: B cell receptor complex
ontology: CC
definition:
An immunoglobulin complex that is present in the plasma membrane of B cells and that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.


go_id: GO:0019817
term: vesicle fusion with peroxisome
ontology: BP
definition:
The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the peroxisome.


go_id: GO:0019819
term: P1 peroxisome
ontology: CC
definition:
A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P1 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content; they contain fewer peroxisomal proteins than the other subforms.


go_id: GO:0019820
term: P2 peroxisome
ontology: CC
definition:
A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P2 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content; they are the least dense of the subforms observed.


go_id: GO:0019821
term: P3 peroxisome
ontology: CC
definition:
A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P3 peroxisomes are formed by fusion of P1 and P2 peroxisomes, and are distinguished from the other subforms on the bases of buoyant density and protein content.


go_id: GO:0019822
term: P4 peroxisome
ontology: CC
definition:
A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P4 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content.


go_id: GO:0019823
term: P5 peroxisome
ontology: CC
definition:
A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P5 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content.


go_id: GO:0019824
term: P6 peroxisome
ontology: CC
definition:
A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P6 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content, and are equivalent to mature peroxisomes.


go_id: GO:0019826
term: oxygen sensor activity
ontology: MF
definition:
Binding to and responding, e.g. by conformational change, to changes in the cellular level of oxygen (O2).


go_id: GO:0019827
term: stem cell population maintenance
ontology: BP
definition:
The process by which an organism or tissue maintains a population of stem cells of a single type.  This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types.


go_id: GO:0019828
term: aspartic-type endopeptidase inhibitor activity
ontology: MF
definition:
Binds to and stops, prevents or reduces the activity of aspartic-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain; the optimum reaction pH is below 5 due to an aspartic residue involved in the catalytic process.


go_id: GO:0019829
term: ATPase-coupled cation transmembrane transporter activity
ontology: MF
definition:
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + cation(out) = ADP + phosphate + cation(in).


go_id: GO:0019836
term: hemolysis by symbiont of host erythrocytes
ontology: BP
definition:
The cytolytic destruction of red blood cells, with the release of intracellular hemoglobin, in the host organism by a symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0019838
term: growth factor binding
ontology: MF
definition:
Binding to a growth factor, proteins or polypeptides that stimulate a cell or organism to grow or proliferate.


go_id: GO:0019840
term: isoprenoid binding
ontology: MF
definition:
Binding to an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.


go_id: GO:0019841
term: retinol binding
ontology: MF
definition:
Binding to retinol, vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A. Retinol is an intermediate in the vision cycle and it also plays a role in growth and differentiation.


go_id: GO:0019842
term: vitamin binding
ontology: MF
definition:
Binding to a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.


go_id: GO:0019852
term: L-ascorbic acid metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species.


go_id: GO:0019853
term: L-ascorbic acid biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of L-ascorbic acid; L-ascorbic acid ionizes to give L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, which is required as a cofactor in the oxidation of prolyl residues to hydroxyprolyl, and other reactions.


go_id: GO:0019854
term: L-ascorbic acid catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of L-ascorbic acid; L-ascorbic acid ionizes to give L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, which is required as a cofactor in the oxidation of prolyl residues to hydroxyprolyl, and other reactions.


go_id: GO:0019856
term: pyrimidine nucleobase biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases.


go_id: GO:0019858
term: cytosine metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving cytosine, 4-amino-2-hydroxypyrimidine, a pyrimidine derivative that is one of the five main bases found in nucleic acids; it occurs widely in cytidine derivatives.


go_id: GO:0019859
term: thymine metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving thymine, 5-methyluracil, one of the two major pyrimidine bases present (as thymidine) in DNA but not found in RNA other than (as ribothymidine) in transfer RNA, where it is a minor base.


go_id: GO:0019860
term: uracil metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving uracil, 2,4-dioxopyrimidine, one of the pyrimidine bases occurring in RNA, but not in DNA.


go_id: GO:0019866
term: organelle inner membrane
ontology: CC
definition:
The inner, i.e. lumen-facing, lipid bilayer of an organelle envelope; usually highly selective to most ions and metabolites.


go_id: GO:0019867
term: outer membrane
ontology: CC
definition:
The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites.


go_id: GO:0019872
term: streptomycin biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of streptomycin, a commonly used antibiotic in cell culture media; it acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome.


go_id: GO:0019874
term: 6-aminohexanoate-cyclic-dimer hydrolase activity
ontology: MF
definition:
Catalysis of the reaction: 1,8-diazacyclotetradecane-2,9-dione + H(2)O = N-(6-aminohexanoyl)-6-aminohexanoate.


go_id: GO:0019876
term: nylon catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of nylon, a polymer where the main polymer chain comprises recurring amide groups; these compounds are generally formed from combinations of diamines, diacids and amino acids.


go_id: GO:0019877
term: diaminopimelate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of diaminopimelate, both as an intermediate in lysine biosynthesis and as a component (as meso-diaminopimelate) of the peptidoglycan of Gram-negative bacterial cell walls.


go_id: GO:0019878
term: lysine biosynthetic process via aminoadipic acid
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of lysine by the aminoadipic pathway.


go_id: GO:0019879
term: peptidyl-thyronine biosynthetic process from peptidyl-tyrosine
ontology: BP
definition:
The formation of peptidyl-thyronine from peptidyl-tyrosine in thyroglobulin by phenyl transfer coupled with the formation of peptidyl-dehydroalanine.


go_id: GO:0019882
term: antigen processing and presentation
ontology: BP
definition:
The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.


go_id: GO:0019883
term: antigen processing and presentation of endogenous antigen
ontology: BP
definition:
The process in which an antigen-presenting cell expresses antigen (peptide or lipid) of endogenous origin on its cell surface in association with an MHC protein complex.


go_id: GO:0019884
term: antigen processing and presentation of exogenous antigen
ontology: BP
definition:
The process in which an antigen-presenting cell expresses antigen (peptide or lipid) of exogenous origin on its cell surface in association with an MHC protein complex.


go_id: GO:0019885
term: antigen processing and presentation of endogenous peptide antigen via MHC class I
ontology: BP
definition:
The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex. The peptide antigen is typically, but not always, processed from a whole protein. Class I here refers to classical class I molecules.


go_id: GO:0019886
term: antigen processing and presentation of exogenous peptide antigen via MHC class II
ontology: BP
definition:
The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein.


go_id: GO:0019888
term: protein phosphatase regulator activity
ontology: MF
definition:
Binds to and modulates the activity of a protein phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a protein substrate molecule.


go_id: GO:0019889
term: pteridine metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving pteridine, pyrazino(2,3-dipyrimidine), the parent structure of pterins and the pteroyl group.


go_id: GO:0019894
term: kinesin binding
ontology: MF
definition:
Interacting selectively and non-covalently and stoichiometrically with kinesin, a member of a superfamily of microtubule-based motor proteins that perform force-generating tasks such as organelle transport and chromosome segregation.


go_id: GO:0019897
term: extrinsic component of plasma membrane
ontology: CC
definition:
The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.


go_id: GO:0019898
term: extrinsic component of membrane
ontology: CC
definition:
The component of a membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.


go_id: GO:0019901
term: protein kinase binding
ontology: MF
definition:
Binding to a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.


go_id: GO:0019905
term: syntaxin binding
ontology: MF
definition:
Binding to a syntaxin, a SNAP receptor involved in the docking of synaptic vesicles at the presynaptic zone of a synapse.


go_id: GO:0019907
term: cyclin-dependent protein kinase activating kinase holoenzyme complex
ontology: CC
definition:
A cyclin-dependent kinase activating kinase complex capable of activating cyclin-dependent kinases by threonine phosphorylation, thus regulating cell cycle progression. consists of a kinase, cyclin and optional assembly factors, in human CDK7, CCNH and MNAT1. CAK activity is itself regulated throughout the cell cycle by T-loop phosphorylation of its kinase component (CDK7 in human). Phosphorylation of serine residues during mitosis inactivates the enzyme. Also capable of CAK phosphorylating the carboxyl-terminal domain (CTD) of RNA polymerase II and other transcription activating proteins, as part of the general transcription factor TFIIH.


go_id: GO:0019910
term: mitochondrial pyruvate dehydrogenase (lipoamide) phosphatase complex
ontology: CC
definition:
A mitochondrial complex of a regulatory and catalytic subunit that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex. An example of this component is found in Mus musculus.


go_id: GO:0019911
term: structural constituent of myelin sheath
ontology: MF
definition:
The action of a molecule that contributes to the structural integrity of the myelin sheath of a nerve.


go_id: GO:0019912
term: cyclin-dependent protein kinase activating kinase activity
ontology: MF
definition:
Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; increases the activity of a cyclin-dependent protein kinase (CDK).


go_id: GO:0019915
term: lipid storage
ontology: BP
definition:
The accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.


go_id: GO:0019918
term: peptidyl-arginine methylation, to symmetrical-dimethyl arginine
ontology: BP
definition:
The process of methylation of peptidyl-arginine to form peptidyl-N(omega),N'(omega)-dimethyl-L-arginine.


go_id: GO:0019919
term: peptidyl-arginine methylation, to asymmetrical-dimethyl arginine
ontology: BP
definition:
The process of methylation of peptidyl-arginine to form peptidyl-N(omega),N(omega)-dimethyl-L-arginine.


go_id: GO:0019920
term: peptidyl-1-thioglycine biosynthetic process, internal
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of internal peptidyl-1-thioglycine, which has an internal C=S bond, instead of an internal C=O bond, in the peptide.


go_id: GO:0019921
term: peptidyl-1-thioglycine biosynthetic process, carboxy-terminal
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of carboxy-terminal peptidyl-1-thioglycine, which has a carboxy-terminal thiocarboxy-C(=O)-SH bond.


go_id: GO:0019926
term: peptidyl-tryptophan oxidation to tryptophyl quinone
ontology: BP
definition:
The oxidation of peptidyl-tryptophan to form tryptophan-6,7-dione, otherwise known as tryptophyl quinone, which is further modified by cross-linking to either tryptophan or cysteine.


go_id: GO:0019927
term: peptide cross-linking via 4'-(S-L-cysteinyl)-L-tryptophyl quinone
ontology: BP
definition:
The cross-linking of a cysteine residue to tryptophyl quinone to form 4'-(S-L-cysteinyl)-L-tryptophyl quinone, a cofactor found at the active site of amine dehydrogenase.


go_id: GO:0019928
term: peptide cross-linking via 3-(S-L-cysteinyl)-L-aspartic acid
ontology: BP
definition:
The cross-linking of a cysteine residue to an aspartic acid residue to form 3-(S-L-cysteinyl)-L-aspartic acid.


go_id: GO:0019929
term: peptide cross-linking via 4-(S-L-cysteinyl)-L-glutamic acid
ontology: BP
definition:
The cross-linking of a cysteine residue to a glutamic acid residue to form 4-(S-L-cysteinyl)-L-glutamic acid.


go_id: GO:0019930
ontology: BP
term:
cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid peptidyl-aspartate ester biosynthetic process from peptidyl-aspartic acid

definition:
The modification of peptidyl-aspartic acid to form peptidyl-cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid aspartate ester, typical of the barley lipid transfer protein 1.


go_id: GO:0019932
term: second-messenger-mediated signaling
ontology: BP
definition:
Any intracellular signal transduction in which the signal is passed on within the cell via a second messenger; a small molecule or ion that can be quickly generated or released from intracellular stores, and can diffuse within the cell. Second-messenger signaling includes production or release of the second messenger, and effectors downstream of the second messenger that further transmit the signal within the cell.


go_id: GO:0019933
term: cAMP-mediated signaling
ontology: BP
definition:
Any intracellular signal transduction in which the signal is passed on within the cell via cyclic AMP (cAMP). Includes production of cAMP, and downstream effectors that further transmit the signal within the cell.


go_id: GO:0019934
term: cGMP-mediated signaling
ontology: BP
definition:
Any intracellular signal transduction in which the signal is passed on within the cell via cyclic GMP (cGMP). Includes production of cGMP, and downstream effectors that further transmit the signal within the cell.


go_id: GO:0019935
term: cyclic-nucleotide-mediated signaling
ontology: BP
definition:
Any intracellular signal transduction in which the signal is passed on within the cell via a cyclic nucleotide. Includes production or release of the cyclic nucleotide, and downstream effectors that further transmit the signal within the cell.


go_id: GO:0019937
term: protein catenane formation via N6-(L-isoaspartyl)-L-lysine, autocatalytic
ontology: BP
definition:
The autocatalytic formation of isopeptide bonds by ligation of peptidyl-lysine and peptidyl-asparagine residues; known to occur in the capsid of some bacteriophage, such as HK97, where it is thought to provide a mechanism for stabilizing the capsid.


go_id: GO:0019938
term: peptide cross-linking via N6-(L-isoaspartyl)-L-lysine, presumed catalytic
ontology: BP
definition:
The formation of isopeptide bonds by ligation of peptidyl-lysine and peptidyl-asparagine residues; occurs in mammals in proteins as yet unidentified by a mechanism probably analogous to that of transglutaminase reactions.


go_id: GO:0019941
term: modification-dependent protein catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent modification of the target protein.


go_id: GO:0019948
term: SUMO activating enzyme activity
ontology: MF
definition:
Catalysis of the activation of the proteolytically processed small ubiquitin-related modifier SUMO, through the formation of an ATP-dependent high-energy thiolester bond.


go_id: GO:0019953
term: sexual reproduction
ontology: BP
definition:
A type of reproduction that combines the genetic material of two gametes (such as a sperm or egg cell or fungal spores). The gametes have an haploid genome (with a single set of chromosomes, the product of a meiotic division) and combines with one another to produce a zygote (diploid).


go_id: GO:0019954
term: asexual reproduction
ontology: BP
definition:
A type of reproduction in which new individuals are produced from a single organism, either from an unfertilized egg or from a single cell or group of cells.


go_id: GO:0019955
term: cytokine binding
ontology: MF
definition:
Binding to a cytokine, any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity.


go_id: GO:0019956
term: chemokine binding
ontology: MF
definition:
Binding to a chemokine. Chemokines are a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.


go_id: GO:0019957
term: C-C chemokine binding
ontology: MF
definition:
Binding to a C-C chemokine; C-C chemokines do not have an amino acid between the first two cysteines of the characteristic four-cysteine motif.


go_id: GO:0019958
term: C-X-C chemokine binding
ontology: MF
definition:
Binding to a C-X-C chemokine; C-X-C chemokines have a single amino acid between the first two cysteines of the characteristic four cysteine motif.


go_id: GO:0019960
term: C-X3-C chemokine binding
ontology: MF
definition:
Binding to a C-X3-C chemokine; C-X3-C chemokines have three amino acids between the first two cysteines of the characteristic four-cysteine motif.


go_id: GO:0019961
term: interferon binding
ontology: MF
definition:
Binding to an interferon, a protein produced by the immune systems of many animals in response to a challenge by a foreign agent.


go_id: GO:0019962
term: type I interferon binding
ontology: MF
definition:
Binding to a type I interferon. Type I interferons include the interferon-alpha, beta, delta, epsilon, zeta, kappa, tau, and omega gene families.


go_id: GO:0019964
term: interferon-gamma binding
ontology: MF
definition:
Binding to interferon-gamma. Interferon gamma is the only member of the type II interferon found so far.


go_id: GO:0019985
term: translesion synthesis
ontology: BP
definition:
The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized DNA polymerase or replication complex inserts a defined nucleotide across from the lesion which allows DNA synthesis to continue beyond the lesion. This process can be mutagenic depending on the damaged nucleotide and the inserted nucleotide.


go_id: GO:0019988
term: charged-tRNA amino acid modification
ontology: BP
definition:
The covalent alteration of an amino acid charged on a tRNA before it is incorporated into a protein, as in N-formylmethionine, selenocysteine or pyrrolysine.


go_id: GO:0019990
term: pteridine catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of pteridine, pyrazino(2,3-dipyrimidine), the parent structure of pterins and the pteroyl group.


go_id: GO:0019991
term: septate junction assembly
ontology: BP
definition:
The assembly of a septate junction, an intercellular junction found in invertebrate epithelia that is characterized by a ladder like appearance in electron micrographs and thought to provide structural strength and to provide a barrier to diffusion of solutes through the intercellular space.


go_id: GO:0020003
term: symbiont-containing vacuole
ontology: CC
definition:
Membrane-bounded vacuole within a host cell in which a symbiont organism resides. The vacuole membrane is derived from both the host and symbiont.


go_id: GO:0020005
term: symbiont-containing vacuole membrane
ontology: CC
definition:
The lipid bilayer surrounding a symbiont-containing vacuole, derived from both the host and symbiont.


go_id: GO:0020006
term: symbiont-containing vacuolar membrane network
ontology: CC
definition:
Tubular network of extensions from the symbiont-containing vacuole membrane that protrude into the host cytoplasm.


go_id: GO:0020007
term: apical complex
ontology: CC
definition:
A group of cytoskeletal structures and associated membrane-bounded organelles found at the anterior end of adult obligate intracellular protozoan parasites in the phylum Apicomplexa. The apical complex is involved in attachment to and penetration of the host cell, and in parasite proliferation.


go_id: GO:0020008
term: rhoptry
ontology: CC
definition:
A large, club-shaped secretory organelle that forms part of the apical complex of an apicomplexan parasite, and consists of a bulbous body and a narrow electron-dense neck that extends through the conoid at the apical tip of the parasite. The rhoptry necks serve as ducts through which the contents of the rhoptries are secreted after attachment to the host has been completed and at the commencement of invasion. Rhoptry proteins function in the biogenesis and host organellar association of the parasitophorous vacuole.


go_id: GO:0020009
term: microneme
ontology: CC
definition:
A small, elongated secretory organelle that forms part of the apical complex, located along the main axis of an apicomplexan parasite cell within the extreme apical region and at the periphery under the inner membrane complex. Of the specialized secretory compartments identified in apicomplexans, micronemes discharge their contents first, during initial contact of the parasite's apical pole with the host cell surface. Micronemal proteins function during parasite attachment and penetration into the target cell.


go_id: GO:0020010
term: conoid
ontology: CC
definition:
A spiral cytoskeletal structure located at the apical end of the apical complex in some apicomplexan parasites. Fibers form a left-handed spiral, and are comprised of tubulin protofilaments organized in a ribbon-like structure that differs from the conventional tubular structure characteristic of microtubules.


go_id: GO:0020013
term: modulation by symbiont of host erythrocyte aggregation
ontology: BP
definition:
Any process in which a symbiont organism modulates the frequency, rate or extent of erythrocyte aggregation in its host organism, e.g. the binding of parasite-infected erythrocytes to uninfected erythrocytes.


go_id: GO:0020014
term: schizogony
ontology: BP
definition:
Cell division by multiple fission in which nuclei and other organelles in the parent cell divide repeatedly and move to the cell periphery before internal membranes develop around them, producing a large number of daughter cells simultaneously.


go_id: GO:0020015
term: glycosome
ontology: CC
definition:
A membrane-bounded organelle found in organisms from the order Kinetoplastida that houses the enzymes of glycolysis.


go_id: GO:0020020
term: food vacuole
ontology: CC
definition:
Vacuole within a parasite used for digestion of the host cell cytoplasm. An example of this component is found in the Apicomplexa.


go_id: GO:0020022
term: acidocalcisome
ontology: CC
definition:
An electron-dense acidic membrane-bounded organelle which contains a matrix of pyrophosphate and polyphosphates with bound calcium and other cations.


go_id: GO:0020023
term: kinetoplast
ontology: CC
definition:
A sub-structure within the large single mitochondrion of kinetoplastid parasites and which is closely associated with the flagellar pocket and basal body of the flagellum.


go_id: GO:0020025
term: subpellicular microtubule
ontology: CC
definition:
Singlet microtubule that lie underneath the inner membrane pellicle complex and emanate from the basal ring of the conoid.


go_id: GO:0020026
term: merozoite dense granule
ontology: CC
definition:
Electron-dense organelle with a granular internal matrix found throughout the merozoite life cycle stage of apicomplexan parasites; contains proteins destined to be secreted into the parasitophorous vacuole following parasite invasion of a host cell.


go_id: GO:0020030
term: infected host cell surface knob
ontology: CC
definition:
Protrusion that develops in the plasma membrane of a parasitized erythrocyte. An example of this component is found in Plasmodium species.


go_id: GO:0020031
term: polar ring of apical complex
ontology: CC
definition:
An electron dense ring at the most anterior position of the apical complex, from which the conoid fibers originate; formed during an invasive life cycle stage of an apicomplexan parasite.


go_id: GO:0020032
term: basal ring of apical complex
ontology: CC
definition:
An electron dense ring at the most posterior position of the apical complex, from which the subpellicular microtubules originate; formed during an invasive life cycle stage of an apicomplexan parasite.


go_id: GO:0020033
term: antigenic variation
ontology: BP
definition:
Any process involved in the biological strategy of changing antigenic determinants on the surface that are exposed to another organism's immune system.


go_id: GO:0020035
term: adhesion of symbiont to microvasculature
ontology: BP
definition:
The adherence of symbiont-infected erythrocytes to microvascular endothelium via symbiont proteins embedded in the membrane of the erythrocyte.


go_id: GO:0020036
term: Maurer's cleft
ontology: CC
definition:
A disk-like structure that appears at the periphery of a red blood cell infected by an apicomplexan parasite, characterized by a translucent lumen and an electron-dense coat of variable thickness; often appears to be tethered to the host cell membrane by fibrous connections with the erythrocyte cytoskeleton.


go_id: GO:0020038
term: subpellicular network
ontology: CC
definition:
A mechanically stable cytoskeletal structure associated with the cytoplasmic face of the pellicle and surrounding the microtubule-based cytoskeleton.


go_id: GO:0020039
term: pellicle
ontology: CC
definition:
The structure enclosing certain parasite cells such as certain apicomplexa and Euglenozoa; consists of the cell membrane with its associated infrastructure of microtubules, microfilaments and other organelles.


go_id: GO:0021501
term: prechordal plate formation
ontology: BP
definition:
The formation of the prechordal plate. The prechordal plate is a thickening of the endoderm at the cranial end of the primitive streak formed by the involution of Spemann's organizer cells. The prechordal plate and the notochord induce the formation of the neural plate from the overlying ectodermal cells.


go_id: GO:0021502
term: neural fold elevation formation
ontology: BP
definition:
The process in which the lateral borders of the neural plate begin to migrate upwards to form the neural folds, caused by the proliferation of the underlying mesoderm.


go_id: GO:0021503
term: neural fold bending
ontology: BP
definition:
The morphogenesis of the neural fold elevations that results in the movement of the tips of the elevations towards each other in order to fuse.


go_id: GO:0021504
term: neural fold hinge point formation
ontology: BP
definition:
The formation of the median and lateral hinge points in the neural folds. These are created by apical constriction and basal expansion of the underlying neural cells. The median hinge point extends for the entire length of the neural tube, and the lateral hinge points do not form in the spinal cord region of the neural tube.


go_id: GO:0021505
term: neural fold folding
ontology: BP
definition:
The process of folding the neuroepithelium around the medial hinge point to create the neural elevations, and around the lateral hinge points to produce convergence of the folds.


go_id: GO:0021506
term: anterior neuropore closure
ontology: BP
definition:
The joining together of the neural folds of the rostral opening of the neural tube. The anterior neuropore appears before the process of neural tube closure is complete.


go_id: GO:0021507
term: posterior neuropore closure
ontology: BP
definition:
The joining together of the neural folds of the caudal opening of the neural tube. The posterior neuropore appears before the process of neural tube closure is complete.


go_id: GO:0021508
term: floor plate formation
ontology: BP
definition:
The formation of a ventral region of glial cells in the neural tube that provides inductive signals for the specification of neuronal cell types. The floor plate is evident at the ventral midline by the neural fold stage.


go_id: GO:0021509
term: roof plate formation
ontology: BP
definition:
The formation of a single row of glia at the dorsal midline of the developing neural tube. This region provides inductive signals for the specification of neuronal cell types and of the specification of neural crest cells. The cells comprising the roof plate are the precursors to radial glial cells.


go_id: GO:0021510
term: spinal cord development
ontology: BP
definition:
The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues.


go_id: GO:0021511
term: spinal cord patterning
ontology: BP
definition:
The regionalization process that regulates the coordinated growth and establishes the non-random spatial arrangement of the spinal cord.


go_id: GO:0021512
term: spinal cord anterior/posterior patterning
ontology: BP
definition:
The process that regulates the coordinated growth and differentiation that establishes the non-random anterior-posterior spatial arrangement of the spinal cord.


go_id: GO:0021513
term: spinal cord dorsal/ventral patterning
ontology: BP
definition:
The process that regulates the coordinated growth and differentiation that establishes the non-random dorsal-ventral spatial arrangement of the spinal cord.


go_id: GO:0021514
term: ventral spinal cord interneuron differentiation
ontology: BP
definition:
The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of ventral spinal cord interneurons. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses. Differentiation includes the processes involved in commitment of a cell to a specific fate.


go_id: GO:0021515
term: cell differentiation in spinal cord
ontology: BP
definition:
The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate.


go_id: GO:0021516
term: dorsal spinal cord development
ontology: BP
definition:
The process whose specific outcome is the progression of the dorsal region of the spinal cord over time, from its formation to the mature structure. The dorsal region of the mature spinal cord contains neurons that process and relay sensory input.


go_id: GO:0021517
term: ventral spinal cord development
ontology: BP
definition:
The process whose specific outcome is the progression of the ventral region of the spinal cord over time, from its formation to the mature structure. The neurons of the ventral region of the mature spinal cord participate in motor output.


go_id: GO:0021518
term: spinal cord commissural neuron specification
ontology: BP
definition:
The process in which a cell becomes capable of differentiating autonomously into a commissural neuron in an environment that is neutral with respect to the developmental pathway.


go_id: GO:0021519
term: spinal cord association neuron specification
ontology: BP
definition:
The process in which a cell becomes capable of differentiating autonomously into an association neuron in an environment that is neutral with respect to the developmental pathway.


go_id: GO:0021520
term: spinal cord motor neuron cell fate specification
ontology: BP
definition:
The process in which a cell becomes capable of differentiating autonomously into a motor neuron in an environment that is neutral with respect to the developmental pathway.


go_id: GO:0021521
term: ventral spinal cord interneuron specification
ontology: BP
definition:
The process in which a cell becomes capable of differentiating autonomously into a ventral spinal cord interneuron in an environment that is neutral with respect to the developmental pathway.


go_id: GO:0021522
term: spinal cord motor neuron differentiation
ontology: BP
definition:
The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of motor neurons. Motor neurons innervate an effector (muscle or glandular) tissue and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate.


go_id: GO:0021523
term: somatic motor neuron differentiation
ontology: BP
definition:
The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of somatic motor neurons. Somatic motor neurons innervate skeletal muscle targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate.


go_id: GO:0021524
term: visceral motor neuron differentiation
ontology: BP
definition:
The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of visceral motor neurons. Visceral motor neurons innervate glandular targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate.


go_id: GO:0021525
term: lateral motor column neuron differentiation
ontology: BP
definition:
The process in which differentiating motor neurons in the neural tube acquire the specialized structural and/or functional features of lateral motor column neurons. Lateral motor column neurons are generated only on limb levels and send axons into the limb mesenchyme. Differentiation includes the processes involved in commitment of a cell to a specific fate.


go_id: GO:0021526
term: medial motor column neuron differentiation
ontology: BP
definition:
The process in which differentiating motor neurons in the neural tube acquire the specialized structural and/or functional features of medial motor column neurons. Medial motor column neurons are generated at all rostrocaudal levels and send axons to the axial muscles (medial group) and to the body wall muscles (lateral group). Differentiation includes the processes involved in commitment of a cell to a specific fate.


go_id: GO:0021527
term: spinal cord association neuron differentiation
ontology: BP
definition:
The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of association neurons. Association neurons are cells located in the dorsal portion of the spinal cord that integrate sensory input. Differentiation includes the processes involved in commitment of a cell to a specific fate.


go_id: GO:0021528
term: commissural neuron differentiation in spinal cord
ontology: BP
definition:
The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of commissural neurons. Commissural neurons in both vertebrates and invertebrates transfer information from one side of their bodies to the other through the midline. Differentiation includes the processes involved in commitment of a cell to a specific fate.


go_id: GO:0021529
term: spinal cord oligodendrocyte cell differentiation
ontology: BP
definition:
The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of oligodendrocytes. Oligodendrocytes are non-neuronal cells. The primary function of oligodendrocytes is the myelination of nerve axons in the central nervous system. Differentiation includes the processes involved in commitment of a cell to a specific fate.


go_id: GO:0021530
term: spinal cord oligodendrocyte cell fate specification
ontology: BP
definition:
The process in which a cell becomes capable of differentiating autonomously into an oligodendrocyte in an environment that is neutral with respect to the developmental pathway.


go_id: GO:0021531
term: spinal cord radial glial cell differentiation
ontology: BP
definition:
The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of radial glial cells. Radial cell precursors differentiate into both neuronal cell types and mature radial glial cells. Mature radial glial cells regulate the axon growth and pathfinding processes that occur during white matter patterning of the developing spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate.


go_id: GO:0021532
term: neural tube patterning
ontology: BP
definition:
The regionalization process that regulates the coordinated growth that establishes the non-random spatial arrangement of the neural tube.


go_id: GO:0021533
term: cell differentiation in hindbrain
ontology: BP
definition:
The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mature cells of the hindbrain. Differentiation includes the processes involved in commitment of a cell to a specific fate.


go_id: GO:0021534
term: cell proliferation in hindbrain
ontology: BP
definition:
The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain.


go_id: GO:0021536
term: diencephalon development
ontology: BP
definition:
The process whose specific outcome is the progression of the diencephalon over time, from its formation to the mature structure. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex.


go_id: GO:0021537
term: telencephalon development
ontology: BP
definition:
The process whose specific outcome is the progression of the telencephalon over time, from its formation to the mature structure. The telencephalon is the paired anteriolateral division of the prosencephalon plus the lamina terminalis from which the olfactory lobes, cerebral cortex, and subcortical nuclei are derived.


go_id: GO:0021538
term: epithalamus development
ontology: BP
definition:
The progression of the epithalamus over time from its initial formation until its mature state. The epithalamus is the small dorsomedial area of the thalamus including the habenular nuclei and associated fiber bundles, the pineal body, and the epithelial roof of the third ventricle.


go_id: GO:0021539
term: subthalamus development
ontology: BP
definition:
The process whose specific outcome is the progression of the subthalamus over time, from its formation to the mature structure. The subthalamus is the anterior part of the diencephalon that lies between the thalamus, hypothalamus, and tegmentum of the mesencephalon, including subthalamic nucleus, zona incerta, the fields of Forel, and the nucleus of ansa lenticularis.


go_id: GO:0021540
term: corpus callosum morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the corpus callosum are generated and organized. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provides communications between the right and left cerebral hemispheres.


go_id: GO:0021541
term: ammon gyrus development
ontology: BP
definition:
The process whose specific outcome is the progression of the ammon gyrus over time, from its formation to the mature structure. The ammon gyrus, often subdivided into the CA1 and CA3 regions, is one of the two interlocking gyri of the hippocampus that is rich in large pyramidal neurons.


go_id: GO:0021542
term: dentate gyrus development
ontology: BP
definition:
The process whose specific outcome is the progression of the dentate gyrus over time, from its formation to the mature structure. The dentate gyrus is one of two interlocking gyri of the hippocampus. It contains granule cells, which project to the pyramidal cells and interneurons of the CA3 region of the ammon gyrus.


go_id: GO:0021543
term: pallium development
ontology: BP
definition:
The process whose specific outcome is the progression of the pallium over time, from its formation to the mature structure. The pallium is the roof region of the telencephalon.


go_id: GO:0021544
term: subpallium development
ontology: BP
definition:
The process whose specific outcome is the progression of the subpallium over time, from its formation to the mature structure. The subpallium is the base region of the telencephalon.


go_id: GO:0021545
term: cranial nerve development
ontology: BP
definition:
The process whose specific outcome is the progression of the cranial nerves over time, from its formation to the mature structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.


go_id: GO:0021546
term: rhombomere development
ontology: BP
definition:
The process whose specific outcome is the progression of the rhombomere over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.


go_id: GO:0021547
term: midbrain-hindbrain boundary initiation
ontology: BP
definition:
The regionalization process that gives rise to the midbrain-hindbrain boundary. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.


go_id: GO:0021548
term: pons development
ontology: BP
definition:
The process whose specific outcome is the progression of the pons over time, from its formation to the mature structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.


go_id: GO:0021549
term: cerebellum development
ontology: BP
definition:
The process whose specific outcome is the progression of the cerebellum over time, from its formation to the mature structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. In mice, the cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.


go_id: GO:0021550
term: medulla oblongata development
ontology: BP
definition:
The process whose specific outcome is the progression of the medulla oblongata over time, from its formation to the mature structure. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.


go_id: GO:0021551
term: central nervous system morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the central nervous system is generated and organized. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.


go_id: GO:0021552
term: midbrain-hindbrain boundary structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the midbrain-hindbrain boundary structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.


go_id: GO:0021553
term: olfactory nerve development
ontology: BP
definition:
The process whose specific outcome is the progression of the olfactory nerve over time, from its formation to the mature structure. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.


go_id: GO:0021554
term: optic nerve development
ontology: BP
definition:
The process whose specific outcome is the progression of the optic nerve over time, from its formation to the mature structure. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.


go_id: GO:0021555
term: midbrain-hindbrain boundary morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the midbrain-hindbrain boundary is generated and organized. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.


go_id: GO:0021556
term: central nervous system formation
ontology: BP
definition:
The process that gives rise to the central nervous system. This process pertains to the initial formation of a structure from unspecified parts. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.


go_id: GO:0021557
term: oculomotor nerve development
ontology: BP
definition:
The process whose specific outcome is the progression of the oculomotor nerve over time, from its formation to the mature structure. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.


go_id: GO:0021558
term: trochlear nerve development
ontology: BP
definition:
The process whose specific outcome is the progression of the trochlear nerve over time, from its formation to the mature structure. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.


go_id: GO:0021559
term: trigeminal nerve development
ontology: BP
definition:
The process whose specific outcome is the progression of the trigeminal nerve over time, from its formation to the mature structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.


go_id: GO:0021560
term: abducens nerve development
ontology: BP
definition:
The process whose specific outcome is the progression of the abducens nerve over time, from its formation to the mature structure. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.


go_id: GO:0021561
term: facial nerve development
ontology: BP
definition:
The process whose specific outcome is the progression of the facial nerve over time, from its formation to the mature structure. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives off nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.


go_id: GO:0021562
term: vestibulocochlear nerve development
ontology: BP
definition:
The process whose specific outcome is the progression of the vestibulocochlear nerve over time, from its formation to the mature structure. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.


go_id: GO:0021563
term: glossopharyngeal nerve development
ontology: BP
definition:
Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.


go_id: GO:0021564
term: vagus nerve development
ontology: BP
definition:
The process whose specific outcome is the progression of the vagus nerve over time, from its formation to the mature structure. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis.


go_id: GO:0021565
term: accessory nerve development
ontology: BP
definition:
The process whose specific outcome is the progression of the accessory nerve over time, from its formation to the mature structure. In mice, the spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.


go_id: GO:0021566
term: hypoglossal nerve development
ontology: BP
definition:
The process whose specific outcome is the progression of the hypoglossal nerve over time, from its formation to the mature structure. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.


go_id: GO:0021567
term: rhombomere 1 development
ontology: BP
definition:
The process whose specific outcome is the progression of rhombomere 1 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


go_id: GO:0021568
term: rhombomere 2 development
ontology: BP
definition:
The process whose specific outcome is the progression of rhombomere 2 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


go_id: GO:0021569
term: rhombomere 3 development
ontology: BP
definition:
The process whose specific outcome is the progression of rhombomere 3 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


go_id: GO:0021570
term: rhombomere 4 development
ontology: BP
definition:
The process whose specific outcome is the progression of rhombomere 4 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


go_id: GO:0021571
term: rhombomere 5 development
ontology: BP
definition:
The process whose specific outcome is the progression of rhombomere 5 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


go_id: GO:0021572
term: rhombomere 6 development
ontology: BP
definition:
The process whose specific outcome is the progression of rhombomere 6 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


go_id: GO:0021573
term: rhombomere 7 development
ontology: BP
definition:
The process whose specific outcome is the progression of rhombomere 7 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


go_id: GO:0021574
term: rhombomere 8 development
ontology: BP
definition:
The process whose specific outcome is the progression of rhombomere 8 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


go_id: GO:0021575
term: hindbrain morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the hindbrain is generated and organized. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions.


go_id: GO:0021576
term: hindbrain formation
ontology: BP
definition:
The process that gives rise to the hindbrain. This process pertains to the initial formation of a structure from unspecified parts. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions.


go_id: GO:0021577
term: hindbrain structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the hindbrain. This process pertains to the physical shaping of a rudimentary structure. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions.


go_id: GO:0021578
term: hindbrain maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the hindbrain to attain its fully functional state. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions.


go_id: GO:0021579
term: medulla oblongata morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the medulla oblongata is generated and organized. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.


go_id: GO:0021580
term: medulla oblongata formation
ontology: BP
definition:
The process that gives rise to the medulla oblongata. This process pertains to the initial formation of a structure from unspecified parts. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.


go_id: GO:0021581
term: medulla oblongata structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the medulla oblongata. This process pertains to the physical shaping of a rudimentary structure. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.


go_id: GO:0021582
term: medulla oblongata maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the medulla oblongata to attain its fully functional state. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.


go_id: GO:0021583
term: pons morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the pons is generated and organized. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.


go_id: GO:0021584
term: pons formation
ontology: BP
definition:
The process that gives rise to the pons. This process pertains to the initial formation of a structure from unspecified parts. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.


go_id: GO:0021585
term: pons structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the pons. This process pertains to the physical shaping of a rudimentary structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.


go_id: GO:0021586
term: pons maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the pons to attain its fully functional state. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.


go_id: GO:0021587
term: cerebellum morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the cerebellum is generated and organized. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.


go_id: GO:0021588
term: cerebellum formation
ontology: BP
definition:
The process that gives rise to the cerebellum. This process pertains to the initial formation of a structure from unspecified parts. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.


go_id: GO:0021589
term: cerebellum structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the cerebellum. This process pertains to the physical shaping of a rudimentary structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.


go_id: GO:0021590
term: cerebellum maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellum to attain its fully functional state. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.


go_id: GO:0021591
term: ventricular system development
ontology: BP
definition:
The process whose specific outcome is the progression of the brain ventricular system over time, from its formation to the mature structure. The brain ventricular system consists of four communicating cavities within the brain that are continuous with the central canal of the spinal cord. These cavities include two lateral ventricles, the third ventricle and the fourth ventricle. Cerebrospinal fluid fills the ventricles and is produced by the choroid plexus.


go_id: GO:0021592
term: fourth ventricle development
ontology: BP
definition:
The process whose specific outcome is the progression of the fourth ventricle over time, from its formation to the mature structure. The fourth ventricle is an irregularly shaped cavity in the rhombencephalon, between the medulla oblongata, the pons, and the isthmus in front, and the cerebellum behind. It is continuous with the central canal of the cord below and with the cerebral aqueduct above, and through its lateral and median apertures it communicates with the subarachnoid space.


go_id: GO:0021593
term: rhombomere morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the rhombomere is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.


go_id: GO:0021594
term: rhombomere formation
ontology: BP
definition:
The process that gives rise to the rhombomere. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.


go_id: GO:0021595
term: rhombomere structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the rhombomere structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.


go_id: GO:0021597
term: central nervous system structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the central nervous system structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.


go_id: GO:0021598
term: abducens nerve morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the abducens nerve is generated and organized. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.


go_id: GO:0021599
term: abducens nerve formation
ontology: BP
definition:
The process that gives rise to the abducens nerve. This process pertains to the initial formation of a structure from unspecified parts. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.


go_id: GO:0021600
term: abducens nerve structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the abducens nerve. This process pertains to the physical shaping of a rudimentary structure. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.


go_id: GO:0021601
term: abducens nerve maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the abducens nerve to attain its fully functional state. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.


go_id: GO:0021602
term: cranial nerve morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the cranial nerves are generated and organized. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.


go_id: GO:0021603
term: cranial nerve formation
ontology: BP
definition:
The process that gives rise to the cranial nerves. This process pertains to the initial formation of a structure from unspecified parts. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.


go_id: GO:0021604
term: cranial nerve structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the cranial nerves. This process pertains to the physical shaping of a rudimentary structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.


go_id: GO:0021605
term: cranial nerve maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for a cranial nerve to attain its fully functional state. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.


go_id: GO:0021606
term: accessory nerve maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the accessory nerve to attain its fully functional state. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.


go_id: GO:0021607
term: accessory nerve morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the accessory nerve is generated and organized. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.


go_id: GO:0021608
term: accessory nerve formation
ontology: BP
definition:
The process that gives rise to the accessory nerve. This process pertains to the initial formation of a structure from unspecified parts. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.


go_id: GO:0021609
term: accessory nerve structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the accessory nerve This process pertains to the physical shaping of a rudimentary structure. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.


go_id: GO:0021610
term: facial nerve morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the facial nerve is generated and organized. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.


go_id: GO:0021611
term: facial nerve formation
ontology: BP
definition:
The process that gives rise to the facial nerve. This process pertains to the initial formation of a structure from unspecified parts. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.


go_id: GO:0021612
term: facial nerve structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the facial nerve. This process pertains to the physical shaping of a rudimentary structure. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.


go_id: GO:0021613
term: facial nerve maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the facial nerve to attain its fully functional state. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.


go_id: GO:0021614
term: glossopharyngeal nerve maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the glossopharyngeal nerve to attain its fully functional state. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.


go_id: GO:0021615
term: glossopharyngeal nerve morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the glossopharyngeal nerve is generated and organized. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.


go_id: GO:0021616
term: glossopharyngeal nerve formation
ontology: BP
definition:
The process that gives rise to the glossopharyngeal nerve. This process pertains to the initial formation of a structure from unspecified parts. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.


go_id: GO:0021617
term: glossopharyngeal nerve structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the glossopharyngeal nerve. This process pertains to the physical shaping of a rudimentary structure. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.


go_id: GO:0021618
term: hypoglossal nerve morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the hypoglossal nerve is generated and organized. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.


go_id: GO:0021619
term: hypoglossal nerve maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the hypoglossal nerve to attain its fully functional state. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.


go_id: GO:0021620
term: hypoglossal nerve formation
ontology: BP
definition:
The process that gives rise to the hypoglossal nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.


go_id: GO:0021621
term: hypoglossal nerve structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the hypoglossal nerve. This process pertains to the physical shaping of a rudimentary structure. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.


go_id: GO:0021622
term: oculomotor nerve morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the oculomotor nerve is generated and organized. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.


go_id: GO:0021623
term: oculomotor nerve formation
ontology: BP
definition:
The process that gives rise to the oculomotor nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.


go_id: GO:0021624
term: oculomotor nerve structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the oculomotor nerve. This process pertains to the physical shaping of a rudimentary structure. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.


go_id: GO:0021625
term: oculomotor nerve maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the oculomotor nerve to attain its fully functional state. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.


go_id: GO:0021626
term: central nervous system maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the central nervous system to attain its fully functional state. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.


go_id: GO:0021627
term: olfactory nerve morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the olfactory nerve is generated and organized. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.


go_id: GO:0021628
term: olfactory nerve formation
ontology: BP
definition:
The process that gives rise to the olfactory nerve. This process pertains to the initial formation of a structure from unspecified parts. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.


go_id: GO:0021629
term: olfactory nerve structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the oculomotor nerve. This process pertains to the physical shaping of a rudimentary structure. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.


go_id: GO:0021630
term: olfactory nerve maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the olfactory nerve to attain its fully functional state. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.


go_id: GO:0021631
term: optic nerve morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the optic nerve is generated and organized. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.


go_id: GO:0021632
term: optic nerve maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the optic nerve to attain its fully functional state. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.


go_id: GO:0021633
term: optic nerve structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the optic nerve. This process pertains to the physical shaping of a rudimentary structure. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.


go_id: GO:0021634
term: optic nerve formation
ontology: BP
definition:
The process that gives rise to the optic nerve. This process pertains to the initial formation of a structure from unspecified parts. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.


go_id: GO:0021635
term: trigeminal nerve maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the trigeminal nerve to attain its fully functional state. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.


go_id: GO:0021636
term: trigeminal nerve morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the trigeminal nerve is generated and organized. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.


go_id: GO:0021637
term: trigeminal nerve structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the oculomotor nerve. This process pertains to the physical shaping of a rudimentary structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.


go_id: GO:0021638
term: trigeminal nerve formation
ontology: BP
definition:
The process that gives rise to the trigeminal nerve. This process pertains to the initial formation of a structure from unspecified parts. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.


go_id: GO:0021639
term: trochlear nerve morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the trochlear nerve is generated and organized. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.


go_id: GO:0021640
term: trochlear nerve maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the trochlear nerve to attain its fully functional state. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.


go_id: GO:0021641
term: trochlear nerve structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the trochlear nerve. This process pertains to the physical shaping of a rudimentary structure. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.


go_id: GO:0021642
term: trochlear nerve formation
ontology: BP
definition:
The process that gives rise to the trochlear nerve. This process pertains to the initial formation of a structure from unspecified parts. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.


go_id: GO:0021643
term: vagus nerve maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the vagus nerve to attain its fully functional state. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis.


go_id: GO:0021644
term: vagus nerve morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the vagus nerve is generated and organized. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis.


go_id: GO:0021645
term: vagus nerve structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the vagus nerve. This process pertains to the physical shaping of a rudimentary structure. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis.


go_id: GO:0021646
term: vagus nerve formation
ontology: BP
definition:
The process that gives rise to the vagus nerve. This process pertains to the initial formation of a structure from unspecified parts. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis.


go_id: GO:0021647
term: vestibulocochlear nerve maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the vestibulocochlear nerve to attain its fully functional state. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.


go_id: GO:0021648
term: vestibulocochlear nerve morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the vestibulocochlear nerve is generated and organized. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.


go_id: GO:0021649
term: vestibulocochlear nerve structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the vestibulocochlear nerve. This process pertains to the physical shaping of a rudimentary structure. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.


go_id: GO:0021650
term: vestibulocochlear nerve formation
ontology: BP
definition:
The process that gives rise to the vestibulocochlear nerve. This process pertains to the initial formation of a structure from unspecified parts. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.


go_id: GO:0021651
term: rhombomere 1 morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of rhombomere 1 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.


go_id: GO:0021652
term: rhombomere 1 formation
ontology: BP
definition:
The process that gives rise to rhombomere 1. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


go_id: GO:0021653
term: rhombomere 1 structural organization
ontology: BP
definition:
The process that contributes to creating the structural organization of rhombomere 1. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.


go_id: GO:0021654
term: rhombomere boundary formation
ontology: BP
definition:
The process that gives rise to a rhombomere boundary. This process pertains to the initial formation of a boundary delimiting a rhombomere. Rhombomeres are transverse segments of the developing rhombencephalon that are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


go_id: GO:0021655
term: rhombomere 2 morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of rhombomere 2 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.


go_id: GO:0021656
term: rhombomere 2 structural organization
ontology: BP
definition:
The process that contributes to creating the structural organization of rhombomere 2. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.


go_id: GO:0021657
term: rhombomere 2 formation
ontology: BP
definition:
The process that gives rise to rhombomere 2. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


go_id: GO:0021658
term: rhombomere 3 morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of rhombomere 3 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.


go_id: GO:0021659
term: rhombomere 3 structural organization
ontology: BP
definition:
The process that contributes to creating the structural organization of rhombomere 3. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.


go_id: GO:0021660
term: rhombomere 3 formation
ontology: BP
definition:
The process that gives rise to rhombomere 3. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


go_id: GO:0021661
term: rhombomere 4 morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of rhombomere 4 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.


go_id: GO:0021662
term: rhombomere 4 structural organization
ontology: BP
definition:
The process that contributes to creating the structural organization of rhombomere 4. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.


go_id: GO:0021663
term: rhombomere 4 formation
ontology: BP
definition:
The process that gives rise to rhombomere 4. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


go_id: GO:0021664
term: rhombomere 5 morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of rhombomere 5 are generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.


go_id: GO:0021665
term: rhombomere 5 structural organization
ontology: BP
definition:
The process that contributes to creating the structural organization of rhombomere 5. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.


go_id: GO:0021666
term: rhombomere 5 formation
ontology: BP
definition:
The process that gives rise to rhombomere 5. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


go_id: GO:0021667
term: rhombomere 6 morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of rhombomere 6 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.


go_id: GO:0021668
term: rhombomere 6 structural organization
ontology: BP
definition:
The process that contributes to creating the structural organization of rhombomere 6. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.


go_id: GO:0021669
term: rhombomere 6 formation
ontology: BP
definition:
The process that gives rise to rhombomere 6. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


go_id: GO:0021670
term: lateral ventricle development
ontology: BP
definition:
The process whose specific outcome is the progression of the lateral ventricles over time, from the formation to the mature structure. The two lateral ventricles are a cavity in each of the cerebral hemispheres derived from the cavity of the embryonic neural tube. They are separated from each other by the septum pellucidum, and each communicates with the third ventricle by the foramen of Monro, through which also the choroid plexuses of the lateral ventricles become continuous with that of the third ventricle.


go_id: GO:0021671
term: rhombomere 7 morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of rhombomere 7 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.


go_id: GO:0021672
term: rhombomere 7 structural organization
ontology: BP
definition:
The process that contributes to creating the structural organization of rhombomere 7. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.


go_id: GO:0021673
term: rhombomere 7 formation
ontology: BP
definition:
The process that gives rise to rhombomere 7. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


go_id: GO:0021674
term: rhombomere 8 morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of rhombomere 8 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.


go_id: GO:0021675
term: nerve development
ontology: BP
definition:
The process whose specific outcome is the progression of a nerve over time, from its formation to the mature structure.


go_id: GO:0021676
term: rhombomere 8 structural organization
ontology: BP
definition:
The process that contributes to creating the structural organization of rhombomere 8. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.


go_id: GO:0021677
term: rhombomere 8 formation
ontology: BP
definition:
The process that gives rise to rhombomere 8. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


go_id: GO:0021678
term: third ventricle development
ontology: BP
definition:
The process whose specific outcome is the progression of the third ventricle over time, from its formation to the mature structure. The third ventricle is the narrow cleft inferior to the corpus callosum, within the diencephalon, between the paired thalami. Its floor is formed by the hypothalamus, its anterior wall by the lamina terminalis, and its roof by ependyma, and it communicates with the fourth ventricle by the cerebral aqueduct, and with the lateral ventricles by the interventricular foramina.


go_id: GO:0021679
term: cerebellar molecular layer development
ontology: BP
definition:
The process whose specific outcome is the progression of the cerebellar molecular layer nerve over time, from its formation to the mature structure. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells.


go_id: GO:0021680
term: cerebellar Purkinje cell layer development
ontology: BP
definition:
The process whose specific outcome is the progression of the cerebellar Purkinje cell layer over time, from its formation to the mature structure. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.


go_id: GO:0021681
term: cerebellar granular layer development
ontology: BP
definition:
The process whose specific outcome is the progression of the cerebellar granule layer over time, from its formation to the mature structure. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.


go_id: GO:0021682
term: nerve maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for a nerve to attain its fully functional state.


go_id: GO:0021683
term: cerebellar granular layer morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the cerebellar granular layer is generated and organized. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.


go_id: GO:0021684
term: cerebellar granular layer formation
ontology: BP
definition:
The process that gives rise to the cerebellar granule layer. This process pertains to the initial formation of a structure from unspecified parts. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.


go_id: GO:0021685
term: cerebellar granular layer structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the cerebellar granule layer. This process pertains to the physical shaping of a rudimentary structure. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.


go_id: GO:0021686
term: cerebellar granular layer maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar granular layer to attain its fully functional state. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.


go_id: GO:0021687
term: cerebellar molecular layer morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the cerebellar molecular layer is generated and organized. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells.


go_id: GO:0021688
term: cerebellar molecular layer formation
ontology: BP
definition:
The process that gives rise to the cerebellar molecular layer. This process pertains to the initial formation of a structure from unspecified parts. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells.


go_id: GO:0021689
term: cerebellar molecular layer structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the cerebellar molecular layer. This process pertains to the physical shaping of a rudimentary structure. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells.


go_id: GO:0021690
term: cerebellar molecular layer maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar molecular layer to attain its fully functional state. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells.


go_id: GO:0021691
term: cerebellar Purkinje cell layer maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar Purkinje cell layer to attain its fully functional state. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.


go_id: GO:0021692
term: cerebellar Purkinje cell layer morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the cerebellar Purkinje cell layer is generated and organized. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.


go_id: GO:0021693
term: cerebellar Purkinje cell layer structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the cerebellar Purkinje cell layer. This process pertains to the physical shaping of a rudimentary structure. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.


go_id: GO:0021694
term: cerebellar Purkinje cell layer formation
ontology: BP
definition:
The process that gives rise to the cerebellar Purkinje cell layer. This process pertains to the initial formation of a structure from unspecified parts. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.


go_id: GO:0021695
term: cerebellar cortex development
ontology: BP
definition:
The process whose specific outcome is the progression of the cerebellar cortex over time, from its formation to the mature structure. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function.


go_id: GO:0021696
term: cerebellar cortex morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the cranial nerves are generated and organized. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function.


go_id: GO:0021697
term: cerebellar cortex formation
ontology: BP
definition:
The process that gives rise to the cerebellar cortex. This process pertains to the initial formation of a structure from unspecified parts. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function.


go_id: GO:0021698
term: cerebellar cortex structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the cerebellar cortex. This process pertains to the physical shaping of a rudimentary structure. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function.


go_id: GO:0021699
term: cerebellar cortex maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar cortex to attain its fully functional state. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function.


go_id: GO:0021700
term: developmental maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure, cell or cellular component to attain its fully functional state.


go_id: GO:0021701
term: cerebellar Golgi cell differentiation
ontology: BP
definition:
The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Golgi cell. Differentiation includes the processes involved in commitment of a neuroblast to a Golgi cell fate. A cerebellar Golgi cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.


go_id: GO:0021702
term: cerebellar Purkinje cell differentiation
ontology: BP
definition:
The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Purkinje cell. Differentiation includes the processes involved in commitment of a neuroblast to a Purkinje cell fate. A Purkinje cell is an inhibitory GABAergic neuron found in the cerebellar cortex that projects to the deep cerebellar nuclei and brain stem.


go_id: GO:0021703
term: locus ceruleus development
ontology: BP
definition:
The process whose specific outcome is the progression of the locus ceruleus over time, from its formation to the mature structure. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic.


go_id: GO:0021704
term: locus ceruleus morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the locus ceruleus is generated and organized. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic.


go_id: GO:0021705
term: locus ceruleus formation
ontology: BP
definition:
The process that gives rise to the locus ceruleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic.


go_id: GO:0021706
term: locus ceruleus maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the locus ceruleus to attain its fully functional state. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic.


go_id: GO:0021707
term: cerebellar granule cell differentiation
ontology: BP
definition:
The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar granule cell. Differentiation includes the processes involved in commitment of a neuroblast to a granule cell fate. A granule cell is a glutamatergic interneuron found in the cerebellar cortex.


go_id: GO:0021708
term: Lugaro cell differentiation
ontology: BP
definition:
The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature Lugaro cell. Differentiation includes the processes involved in commitment of a neuroblast to a Lugaro cell fate. A Lugaro cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.


go_id: GO:0021709
term: cerebellar basket cell differentiation
ontology: BP
definition:
The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar basket cell. Differentiation includes the processes involved in commitment of a neuroblast to a cerebellar basket cell fate. A cerebellar basket cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.


go_id: GO:0021710
term: cerebellar stellate cell differentiation
ontology: BP
definition:
The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar stellate cell. Differentiation includes the processes involved in commitment of a neuroblast to a cerebellar stellate cell fate. A cerebellar stellate cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.


go_id: GO:0021711
term: cerebellar unipolar brush cell differentiation
ontology: BP
definition:
The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature unipolar brush cell in the cerebellum. Differentiation includes the processes involved in commitment of a neuroblast to a unipolar brush cell fate. A unipolar brush cell is a glutamatergic interneuron found in the cerebellar cortex.


go_id: GO:0021712
term: candelabrum cell differentiation
ontology: BP
definition:
The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature candelabrum cell. Differentiation includes the processes involved in commitment of a neuroblast to a candelabrum cell fate. A candelabrum cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.


go_id: GO:0021713
term: inferior olivary nucleus development
ontology: BP
definition:
The process whose specific outcome is the progression of the inferior olivary nucleus over time, from its formation to the mature structure. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.


go_id: GO:0021714
term: inferior olivary nucleus morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the inferior olivary nucleus is generated and organized. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.


go_id: GO:0021715
term: inferior olivary nucleus formation
ontology: BP
definition:
The process that gives rise to the inferior olivary nucleus. This process pertains to the initial formation of a structure from unspecified parts. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.


go_id: GO:0021716
term: inferior olivary nucleus structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the inferior olivary nucleus structure. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.


go_id: GO:0021717
term: inferior olivary nucleus maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the inferior olivary nucleus to attain its fully functional state. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.


go_id: GO:0021718
term: superior olivary nucleus development
ontology: BP
definition:
The process whose specific outcome is the progression of the superior olivary nucleus over time, from its formation to the mature structure. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound.


go_id: GO:0021719
term: superior olivary nucleus morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the superior olivary nucleus is generated and organized. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound.


go_id: GO:0021720
term: superior olivary nucleus formation
ontology: BP
definition:
The process that gives rise to the superior olivary nucleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound.


go_id: GO:0021721
term: superior olivary nucleus structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the superior olivary nucleus structure. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound.


go_id: GO:0021722
term: superior olivary nucleus maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the superior olivary nucleus to attain its fully functional state. The superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound.


go_id: GO:0021723
term: medullary reticular formation development
ontology: BP
definition:
The process whose specific outcome is the progression of the medullary reticular formation over time, from its formation to the mature structure. The medullary reticular formation is a series of brain nuclei located in the medulla oblongata.


go_id: GO:0021724
term: inferior raphe nucleus development
ontology: BP
definition:
The process whose specific outcome is the progression of the inferior raphe nucleus over time, from its formation to the mature structure.


go_id: GO:0021725
term: superior raphe nucleus development
ontology: BP
definition:
The process whose specific outcome is the progression of the superior raphe nucleus over time, from its formation to the mature structure.


go_id: GO:0021726
term: lateral reticular nucleus development
ontology: BP
definition:
The process whose specific outcome is the progression of the lateral reticular nucleus over time, from its formation to the mature structure.


go_id: GO:0021727
term: intermediate reticular formation development
ontology: BP
definition:
The process whose specific outcome is the progression of the intermediate reticular formation over time, from its formation to the mature structure.


go_id: GO:0021728
term: inferior reticular formation development
ontology: BP
definition:
The process whose specific outcome is the progression of the inferior reticular formation over time, from its formation to the mature structure.


go_id: GO:0021729
term: superior reticular formation development
ontology: BP
definition:
The process whose specific outcome is the progression of the superior reticular formation over time, from its formation to the mature structure.


go_id: GO:0021730
term: trigeminal sensory nucleus development
ontology: BP
definition:
The process whose specific outcome is the progression of the trigeminal sensory nucleus over time, from its formation to the mature structure.


go_id: GO:0021731
term: trigeminal motor nucleus development
ontology: BP
definition:
The process whose specific outcome is the progression of the trigeminal motor nucleus over time, from its formation to the mature structure.


go_id: GO:0021732
term: midbrain-hindbrain boundary maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.


go_id: GO:0021735
term: dentate nucleus development
ontology: BP
definition:
The process whose specific outcome is the progression of the dentate nucleus over time, from its formation to the mature structure.


go_id: GO:0021736
term: globose nucleus development
ontology: BP
definition:
The process whose specific outcome is the progression of the globose nucleus over time, from its formation to the mature structure.


go_id: GO:0021737
term: emboliform nucleus development
ontology: BP
definition:
The process whose specific outcome is the progression of the emboliform nucleus over time, from its formation to the mature structure.


go_id: GO:0021738
term: fastigial nucleus development
ontology: BP
definition:
The process whose specific outcome is the progression of the fastigial nucleus over time, from its formation to the mature structure.


go_id: GO:0021739
term: mesencephalic trigeminal nucleus development
ontology: BP
definition:
The process whose specific outcome is the progression of the mesencephalic trigeminal nucleus over time, from its formation to the mature structure.


go_id: GO:0021740
term: principal sensory nucleus of trigeminal nerve development
ontology: BP
definition:
The process whose specific outcome is the progression of the pontine nucleus over time, from its formation to the mature structure.


go_id: GO:0021741
term: spinal trigeminal nucleus development
ontology: BP
definition:
The process whose specific outcome is the progression of the spinal trigeminal nucleus over time, from its formation to the mature structure.


go_id: GO:0021742
term: abducens nucleus development
ontology: BP
definition:
The process whose specific outcome is the progression of the abducens nucleus over time, from its formation to the mature structure.


go_id: GO:0021743
term: hypoglossal nucleus development
ontology: BP
definition:
The process whose specific outcome is the progression of the hypoglossal nucleus over time, from its formation to the mature structure.


go_id: GO:0021744
term: dorsal motor nucleus of vagus nerve development
ontology: BP
definition:
The process whose specific outcome is the progression of the dorsal motor nucleus of the vagus nerve over time, from its formation to the mature structure.


go_id: GO:0021745
term: nucleus ambiguus development
ontology: BP
definition:
The process whose specific outcome is the progression of the nucleus ambiguus over time, from its formation to the mature structure.


go_id: GO:0021746
term: solitary nucleus development
ontology: BP
definition:
The process whose specific outcome is the progression of the solitary nucleus over time, from its formation to the mature structure.


go_id: GO:0021747
term: cochlear nucleus development
ontology: BP
definition:
The process whose specific outcome is the progression of the cochlear nucleus over time, from its formation to the mature structure.


go_id: GO:0021748
term: dorsal cochlear nucleus development
ontology: BP
definition:
The process whose specific outcome is the progression of the dorsal cochlear nucleus over time, from its formation to the mature structure.


go_id: GO:0021749
term: ventral cochlear nucleus development
ontology: BP
definition:
The process whose specific outcome is the progression of the ventral cochlear nucleus over time, from its formation to the mature structure.


go_id: GO:0021750
term: vestibular nucleus development
ontology: BP
definition:
The process whose specific outcome is the progression of the vestibular nucleus over time, from its formation to the mature structure.


go_id: GO:0021751
term: salivary nucleus development
ontology: BP
definition:
The process whose specific outcome is the progression of a salivary nucleus over time, from its formation to the mature structure.


go_id: GO:0021752
term: inferior salivary nucleus development
ontology: BP
definition:
The process whose specific outcome is the progression of the inferior salivary nucleus over time, from its formation to the mature structure.


go_id: GO:0021753
term: superior salivary nucleus development
ontology: BP
definition:
The process whose specific outcome is the progression of the superior salivary nucleus over time, from its formation to the mature structure.


go_id: GO:0021754
term: facial nucleus development
ontology: BP
definition:
The process whose specific outcome is the progression of the facial nucleus over time, from its formation to the mature structure.


go_id: GO:0021755
term: eurydendroid cell differentiation
ontology: BP
definition:
The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature eurydendroid cell. Differentiation includes the processes involved in commitment of a neuroblast to a eurydendroid cell fate. A eurydendroid cell is an efferent neuron found in the cerebellar cortex of teleosts.


go_id: GO:0021756
term: striatum development
ontology: BP
definition:
The progression of the striatum over time from its initial formation until its mature state. The striatum is a region of the forebrain consisting of the caudate nucleus, putamen and fundus striati.


go_id: GO:0021757
term: caudate nucleus development
ontology: BP
definition:
The progression of the caudate nucleus over time from its initial formation until its mature state. The caudate nucleus is the C-shaped structures of the striatum containing input neurons involved with control of voluntary movement in the brain.


go_id: GO:0021758
term: putamen development
ontology: BP
definition:
The progression of the putamen over time from its initial formation until its mature state. The putamen is the lens-shaped basal ganglion involved with control of voluntary movement in the brain.


go_id: GO:0021759
term: globus pallidus development
ontology: BP
definition:
The progression of the globus pallidus over time from its initial formation until its mature state. The globus pallidus is one of the basal ganglia involved with control of voluntary movement in the brain.


go_id: GO:0021761
term: limbic system development
ontology: BP
definition:
The progression of the limbic system over time from its initial formation until its mature state. The limbic system is a collection of structures in the brain involved in emotion, motivation and emotional aspects of memory.


go_id: GO:0021762
term: substantia nigra development
ontology: BP
definition:
The progression of the substantia nigra over time from its initial formation until its mature state. The substantia nigra is the layer of gray substance that separates the posterior parts of the cerebral peduncles (tegmentum mesencephali) from the anterior parts; it normally includes a posterior compact part with many pigmented cells (pars compacta) and an anterior reticular part whose cells contain little pigment (pars reticularis).


go_id: GO:0021763
term: subthalamic nucleus development
ontology: BP
definition:
The progression of the subthalamic nucleus over time from its initial formation until its mature state. The subthalamic nucleus is the lens-shaped nucleus located in the ventral part of the subthalamus on the inner aspect of the internal capsule that is concerned with the integration of somatic motor function.


go_id: GO:0021764
term: amygdala development
ontology: BP
definition:
The progression of the amygdala over time from its initial formation until its mature state. The amygdala is an almond-shaped set of neurons in the medial temporal lobe of the brain that play a key role in processing emotions such as fear and pleasure.


go_id: GO:0021765
term: cingulate gyrus development
ontology: BP
definition:
The progression of the cingulate gyrus over time from its initial formation until its mature state. The cingulate gyrus is a ridge in the cerebral cortex located dorsal to the corpus callosum.


go_id: GO:0021767
term: mammillary body development
ontology: BP
definition:
The progression of the mammillary body over time from its initial formation until its mature state. The mammillary body is a protrusion at the posterior end of the hypothalamus that contains hypothalamic nuclei.


go_id: GO:0021768
term: nucleus accumbens development
ontology: BP
definition:
The progression of the nucleus accumbens over time from its initial formation until its mature state. The nucleus accumbens is a collection of pleomorphic cells in the caudal part of the anterior horn of the lateral ventricle, in the region of the olfactory tubercle, lying between the head of the caudate nucleus and the anterior perforated substance. It is part of the ventral striatum, a composite structure considered part of the basal ganglia.


go_id: GO:0021769
term: orbitofrontal cortex development
ontology: BP
definition:
The progression of the orbitofrontal cortex over time from its initial formation until its mature state. The orbitofrontal cortex is a cerebral cortex region located in the frontal lobe.


go_id: GO:0021770
term: parahippocampal gyrus development
ontology: BP
definition:
The progression of the parahippocampal gyrus over time from its initial formation until its mature state. The parahippocampal gyrus is a ridge in the cerebral cortex.


go_id: GO:0021771
term: lateral geniculate nucleus development
ontology: BP
definition:
The progression of the lateral geniculate nucleus over time from its initial formation until its mature state. The lateral geniculate nucleus is the primary processor of visual information received from the retina.


go_id: GO:0021772
term: olfactory bulb development
ontology: BP
definition:
The progression of the olfactory bulb over time from its initial formation until its mature state. The olfactory bulb coordinates neuronal signaling involved in the perception of smell. It receives input from the sensory neurons and outputs to the olfactory cortex.


go_id: GO:0021773
term: striatal medium spiny neuron differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a medium spiny neuron residing in the striatum.


go_id: GO:0021774
term: retinoic acid receptor signaling pathway involved in ventral spinal cord interneuron specification
ontology: BP
definition:
The series of molecular signals initiated by binding of a ligand to a retinoic acid receptor in a precursor cell in the ventral spinal cord that contributes to the commitment of the precursor cell to an interneuron fate.


go_id: GO:0021775
term: smoothened signaling pathway involved in ventral spinal cord interneuron specification
ontology: BP
definition:
The series of molecular signals initiated by binding of a ligand to the transmembrane receptor smoothened in a precursor cell in the ventral spinal cord that contributes to the commitment of the precursor cell to an interneuron fate.


go_id: GO:0021776
term: smoothened signaling pathway involved in spinal cord motor neuron cell fate specification
ontology: BP
definition:
The series of molecular signals initiated by binding of a ligand to the transmembrane receptor smoothened in a precursor cell in the spinal cord that contributes to the process of a precursor cell becoming capable of differentiating autonomously into a motor neuron in an environment that is neutral with respect to the developmental pathway.


go_id: GO:0021778
term: oligodendrocyte cell fate specification
ontology: BP
definition:
The process in which a cell becomes capable of differentiating autonomously into an oligodendrocyte in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.


go_id: GO:0021779
term: oligodendrocyte cell fate commitment
ontology: BP
definition:
The process in which the developmental fate of a cell becomes restricted such that it will develop into an oligodendrocyte.


go_id: GO:0021780
term: glial cell fate specification
ontology: BP
definition:
The process in which a cell becomes capable of differentiating autonomously into a glial cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.


go_id: GO:0021781
term: glial cell fate commitment
ontology: BP
definition:
The process in which the developmental fate of a cell becomes restricted such that it will develop into a glial cell.


go_id: GO:0021782
term: glial cell development
ontology: BP
definition:
The process aimed at the progression of a glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.


go_id: GO:0021783
term: preganglionic parasympathetic fiber development
ontology: BP
definition:
The process whose specific outcome is the progression of a preganglionic parasympathetic fiber over time, from its formation to the mature structure. A preganglionic parasympathetic fiber is a cholinergic axonal fiber projecting from the CNS to a parasympathetic ganglion.


go_id: GO:0021784
term: postganglionic parasympathetic fiber development
ontology: BP
definition:
The process whose specific outcome is the progression of the postganglionic portion of the parasympathetic fiber over time, from its formation to the mature structure. The parasympathetic fiber is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia.


go_id: GO:0021785
term: branchiomotor neuron axon guidance
ontology: BP
definition:
The process in which a branchiomotor neuron growth cone is directed to a specific target site. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.


go_id: GO:0021786
term: branchiomotor neuron axon guidance in neural tube
ontology: BP
definition:
The process in which a branchiomotor neuron growth cone in the neural tube is directed to a specific target site in the neural tube. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.


go_id: GO:0021787
term: chemorepulsion of branchiomotor neuron axon in neural tube
ontology: BP
definition:
The process in which a branchiomotor neuron growth cone in the neural tube is directed to a specific target site in the neural tube in response to a repulsive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.


go_id: GO:0021788
term: chemoattraction of branchiomotor neuron axon in neural tube
ontology: BP
definition:
The process in which a branchiomotor neuron growth cone in the neural tube is directed to a specific target site in the neural tube in response to an attractive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.


go_id: GO:0021789
term: branchiomotor neuron axon guidance in branchial arch mesenchyme
ontology: BP
definition:
The process in which a branchiomotor neuron growth cone in the branchial arch mesenchyme is directed to a specific target site in the branchial arch mesenchyme. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.


go_id: GO:0021790
term: chemorepulsion of branchiomotor neuron axon in branchial arch mesenchyme
ontology: BP
definition:
The process in which a branchiomotor neuron growth cone in the branchial arch mesenchyme is directed to a specific target site in the branchial arch mesenchyme in response to a repulsive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.


go_id: GO:0021791
term: chemoattraction of branchiomotor neuron axon in branchial arch mesenchyme
ontology: BP
definition:
The process in which a branchiomotor neuron growth cone in the branchial arch mesenchyme is directed to a specific target site in the branchial arch mesenchyme in response to an attractive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.


go_id: GO:0021792
term: chemoattraction of branchiomotor axon
ontology: BP
definition:
The process in which a branchiomotor neuron growth cone is directed to a specific target site in response to an attractive chemical signal. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.


go_id: GO:0021793
term: chemorepulsion of branchiomotor axon
ontology: BP
definition:
The process in which a branchiomotor neuron growth cone is directed to a specific target site in response to a repulsive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.


go_id: GO:0021794
term: thalamus development
ontology: BP
definition:
The process in which the thalamus changes over time, from its initial formation to its mature state.


go_id: GO:0021796
term: cerebral cortex regionalization
ontology: BP
definition:
The regionalization process that results in the creation of areas within the cerebral cortex that will direct the behavior of cell migration and differentiation as the cortex develops.


go_id: GO:0021797
term: forebrain anterior/posterior pattern specification
ontology: BP
definition:
The creation of specific areas of progenitor domains along the anterior-posterior axis of the developing forebrain.


go_id: GO:0021798
term: forebrain dorsal/ventral pattern formation
ontology: BP
definition:
The formation of specific regional progenitor domains along the dorsal-ventral axis in the developing forebrain.


go_id: GO:0021799
term: cerebral cortex radially oriented cell migration
ontology: BP
definition:
The migration of cells in the developing cerebral cortex in which cells move from the ventricular and/or subventricular zone toward the surface of the brain.


go_id: GO:0021800
term: cerebral cortex tangential migration
ontology: BP
definition:
The migration of cells in the cerebral cortex in which cells move orthogonally to the direction of radial migration and do not use radial glial cell processes as substrates for migration.


go_id: GO:0021801
term: cerebral cortex radial glia-guided migration
ontology: BP
definition:
The radial migration of neuronal or glial precursor cells along radial glial cells during the development of the cerebral cortex.


go_id: GO:0021802
term: somal translocation
ontology: BP
definition:
The radial migration of cells from the ventricular zone that is independent of radial glial cells. Cells extend processes that terminate at the pial surface and follow the processes as they migrate.


go_id: GO:0021805
term: cell movement involved in somal translocation
ontology: BP
definition:
The movement of a cell body from the ventricular zone to the pial surface with a concomitant shortening of the process that extends to the pial surface.


go_id: GO:0021806
term: initiation of movement involved in cerebral cortex radial glia guided migration
ontology: BP
definition:
The initial stages of cell motility involved in the glial-mediated movement of cells in the developing cerebral cortex.


go_id: GO:0021807
term: motogenic signaling initiating cell movement in cerebral cortex
ontology: BP
definition:
The interaction of soluble factors and receptors that result in the movement of cells in the primitive cerebral cortex.


go_id: GO:0021808
ontology: BP
term:
cytosolic calcium signaling involved in initiation of cell movement in glial-mediated radial cell migration

definition:
The process that results in the fluctuations in intracellular calcium that are responsible for the initiation of movement as a component of the process of cerebral cortex glial-mediated radial migration.


go_id: GO:0021809
ontology: BP
term:
neurotrophic factor signaling initiating cell movement, involved in cerebral cortex radial glia guided migration

definition:
Signaling between members of the neurotrophin family and their receptors that result in the start of cell motility as a component of the process of cerebral cortex glial-mediated radial migration.


go_id: GO:0021810
ontology: BP
term:
neurotransmitter signaling initiating cell movement, involved in cerebral cortex radial glia guided migration

definition:
Signaling by neurotransmitters and their receptors that results in the initiation of movement of cells as a component of the process of glial-mediated radial migration.


go_id: GO:0021811
ontology: BP
term:
growth factor signaling initiating cell movement involved in cerebral cortex radial glia guided migration

definition:
Signaling between growth factors and their receptors that results in the start of cell movement, where this process is involved in glial-mediated radial migration in the cerebral cortex.


go_id: GO:0021812
term: neuronal-glial interaction involved in cerebral cortex radial glia guided migration
ontology: BP
definition:
The changes in adhesion between neuronal cells and glial cells as a component of the process of cerebral cortex glial-mediated radial cell migration.


go_id: GO:0021813
ontology: BP
term:
cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration

definition:
The interaction between two cells that modulates the association of a neuronal cell and a glial cell involved in glial-mediated radial cell migration in the cerebral cortex.


go_id: GO:0021814
term: cell motility involved in cerebral cortex radial glia guided migration
ontology: BP
definition:
The movement of a cell along the process of a radial glial cell involved in cerebral cortex glial-mediated radial migration.


go_id: GO:0021815
term: modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration
ontology: BP
definition:
Rearrangements of the microtubule cytoskeleton that contribute to the movement of cells along radial glial cells as a component of the process of cerebral cortex glial-mediated radial migration.


go_id: GO:0021816
ontology: BP
term:
extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration

definition:
The rearrangements of the microtubule cytoskeleton that result in the extension of a leading process, where this process is involved in the movement of cells along radial glial cells.


go_id: GO:0021817
term: nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration
ontology: BP
definition:
The microtubule-mediated movement of the nucleus that is required for the movement of cells along radial glial fibers as a component of the process of cerebral cortex glial-mediated radial cell migration.


go_id: GO:0021818
ontology: BP
term:
modulation of the microfilament cytoskeleton involved in cell locomotion in cerebral cortex radial glia guided migration

definition:
The changes in the actin cytoskeleton that are necessary for the movement of cells along radial glial cells as a component of the process of cerebral cortex glial-mediated radial cell migration.


go_id: GO:0021819
term: layer formation in cerebral cortex
ontology: BP
definition:
The detachment of cells from radial glial fibers at the appropriate time when they cease to migrate and form distinct layer in the cerebral cortex.


go_id: GO:0021820
ontology: BP
term:
extracellular matrix organization in marginal zone involved in cerebral cortex radial glia guided migration

definition:
The process that leads to the deposition of extracellular matrix signals in the marginal zone of the developing cerebral cortex. This extracellular matrix controls the movement of migrating cells. In mammals, the matrix is modified by Cajal-Retzius cells.


go_id: GO:0021821
term: negative regulation of cell-glial cell adhesion involved in cerebral cortex lamination
ontology: BP
definition:
The process that results in the release of migrating cells from their interaction with radial glial cells as a component of the process of cerebral cortex glial-mediated radial cell migration.


go_id: GO:0021822
term: negative regulation of cell motility involved in cerebral cortex radial glia guided migration
ontology: BP
definition:
The intracellular signaling pathway that results in the cessation of cell movement involved in lamination of the cerebral cortex.


go_id: GO:0021823
term: cerebral cortex tangential migration using cell-cell interactions
ontology: BP
definition:
The process in which neurons interact with each other to promote migration along a tangential plane.


go_id: GO:0021824
term: cerebral cortex tangential migration using cell-axon interactions
ontology: BP
definition:
The movement of cerebral cortex neuronal precursors tangentially through the cortex using interaction of the migrating cells with axons of other neurons.


go_id: GO:0021825
term: substrate-dependent cerebral cortex tangential migration
ontology: BP
definition:
The process where neuronal precursors migrate tangentially in the cerebral cortex, primarily guided through physical cell-cell interactions.


go_id: GO:0021826
term: substrate-independent telencephalic tangential migration
ontology: BP
definition:
The process where neuronal precursors migrate tangentially in the telencephalon, primarily guided by interactions that do not require cell-cell contact.


go_id: GO:0021827
term: postnatal olfactory bulb interneuron migration
ontology: BP
definition:
The migration of olfactory bulb interneuron precursors in the cerebral cortex that occurs after birth.


go_id: GO:0021828
term: gonadotrophin-releasing hormone neuronal migration to the hypothalamus
ontology: BP
definition:
The directional movement of a gonadotrophin-releasing hormone producing neuron from the nasal placode to the hypothalamus.


go_id: GO:0021829
term: oligodendrocyte cell migration from the subpallium to the cortex
ontology: BP
definition:
The directed movement of oligodendrocytes from the subpallium to the cerebral cortex during forebrain development.


go_id: GO:0021830
term: interneuron migration from the subpallium to the cortex
ontology: BP
definition:
The directed movement of interneurons from the subpallium to the cortex during forebrain development.


go_id: GO:0021831
term: embryonic olfactory bulb interneuron precursor migration
ontology: BP
definition:
The directed movement of individual interneuron precursors during the embryonic development of the olfactory bulb.


go_id: GO:0021832
term: cell-cell adhesion involved in cerebral cortex tangential migration using cell-cell interactions
ontology: BP
definition:
The attachment of cells to one another to form groups of cells involved in cerebral cortex tangential migration.


go_id: GO:0021833
term: cell-matrix adhesion involved in tangential migration using cell-cell interactions
ontology: BP
definition:
The interaction of a cell and the extracellular matrix involved in the directed tangential movement of cells mediated by cell-cell interactions in the developing cerebral cortex.


go_id: GO:0021834
term: chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration
ontology: BP
definition:
The creation and reception of signals that guide olfactory bulb interneuron precursors down concentration gradients towards the olfactory bulb.


go_id: GO:0021835
term: chemoattraction involved in embryonic olfactory bulb interneuron precursor migration
ontology: BP
definition:
The creation and reception of signals that result in the migration of interneuron precursors up a concentration gradient towards the olfactory bulb.


go_id: GO:0021836
term: chemorepulsion involved in postnatal olfactory bulb interneuron migration
ontology: BP
definition:
The creation and reception of signals that repel olfactory bulb interneurons from the subventricular zone as a component process in tangential migration.


go_id: GO:0021838
term: motogenic signaling involved in interneuron migration from the subpallium to the cortex
ontology: BP
definition:
The creation and reception of signals that result in the directional movement of interneuron precursors from the subpallium to the cortex.


go_id: GO:0021839
ontology: BP
term:
interneuron-substratum interaction involved in interneuron migration from the subpallium to the cortex

definition:
The process in which migrating interneurons interact with an external substratum as a component of migration from the subpallium to the cortex.


go_id: GO:0021840
term: directional guidance of interneurons involved in migration from the subpallium to the cortex
ontology: BP
definition:
The creation and reception of signals that control the direction of migration of interneurons as a component of the process of migration from the subpallium to the cortex.


go_id: GO:0021841
term: chemoattraction involved in interneuron migration from the subpallium to the cortex
ontology: BP
definition:
The creation and reception of signals that result in the movement of interneurons toward the signal, where this process is involved in migration from the subpallium to the cortex.


go_id: GO:0021842
term: chemorepulsion involved in interneuron migration from the subpallium to the cortex
ontology: BP
definition:
The creation and reception of signals that result in the movement of interneurons away from the signal during migration from the subpallium to the cortex.


go_id: GO:0021843
term: substrate-independent telencephalic tangential interneuron migration
ontology: BP
definition:
The directional movement of tangentially migrating interneurons that are not guided by attaching to extracellular substrates.


go_id: GO:0021844
term: interneuron sorting involved in substrate-independent cerebral cortex tangential migration
ontology: BP
definition:
The establishment and response to guidance cues that distribute interneurons to different cerebral cortex structures.


go_id: GO:0021845
ontology: BP
term:
neurotransmitter-mediated guidance of interneurons involved in substrate-independent cerebral cortex tangential migration

definition:
The response of migrating interneurons to neurotransmitters that alter electrical activity in cells in calcium dependent manner.


go_id: GO:0021847
term: ventricular zone neuroblast division
ontology: BP
definition:
The proliferation of neuroblasts in the ventricular zone of the cerebral cortex. The neuronal progenitors of these cells will migrate radially.


go_id: GO:0021848
term: neuroblast division in subpallium
ontology: BP
definition:
The division of neuroblasts in the subpallium area of the forebrain. The interneuron precursors that these cells give rise to include GABAergic interneurons and will migrate tangentially.


go_id: GO:0021849
term: neuroblast division in subventricular zone
ontology: BP
definition:
The division of neuroblasts in the subventricular zone of the forebrain. The interneuron precursors that these cells give rise to include adult olfactory bulb interneurons and migrate tangentially.


go_id: GO:0021851
term: neuroblast division in dorsal lateral ganglionic eminence
ontology: BP
definition:
The division of neuroblasts in the dorsal region of the lateral ganglionic eminence. These cells give rise to embryonic interneuron precursors that will migrate tangentially to the olfactory bulb.


go_id: GO:0021852
term: pyramidal neuron migration to cerebral cortex
ontology: BP
definition:
The migration of a pyramidal neuron precursor from the ventricular zone to the correct layer of the cerebral cortex.


go_id: GO:0021854
term: hypothalamus development
ontology: BP
definition:
The progression of the hypothalamus region of the forebrain, from its initial formation to its mature state.


go_id: GO:0021856
term: hypothalamic tangential migration using cell-axon interactions
ontology: BP
definition:
The movement of a hypothalamic neuronal precursor tangentially through the forebrain using an interaction of the migrating cells with axons of other neurons.


go_id: GO:0021858
term: GABAergic neuron differentiation in basal ganglia
ontology: BP
definition:
The process in which a neuroblast acquires the specialized structural and functional features of a GABAergic inhibitory neuron in the basal ganglia. Differentiation includes the processes involved in commitment of a neuroblast to a GABAergic neuron.


go_id: GO:0021859
term: pyramidal neuron differentiation
ontology: BP
definition:
The process in which a neuroblast or one of its progeny commits to a pyramidal neuron fate, migrates from the ventricular zone to the appropriate layer in the cortex and develops into a mature neuron.


go_id: GO:0021861
term: forebrain radial glial cell differentiation
ontology: BP
definition:
The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, specialized bipotential progenitors cells of the forebrain. Differentiation includes the processes involved in commitment of a cell to a specific fate.


go_id: GO:0021862
term: early neuron differentiation in forebrain
ontology: BP
definition:
The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of neurons. Differentiation includes the processes involved in commitment of a cell to a specific fate.


go_id: GO:0021863
term: forebrain neuroblast differentiation
ontology: BP
definition:
The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of basal progenitor cells, neuroblasts that lose their contacts with the ventricular surface. Differentiation includes the processes involved in commitment of a cell to a specific fate.


go_id: GO:0021870
term: Cajal-Retzius cell differentiation
ontology: BP
definition:
The process in which a neuroblast acquires specialized structural and/or functional features of a Cajal-Retzius cell, one of a transient population of pioneering neurons in the cerebral cortex. These cells are slender bipolar cells of the developing marginal zone. One feature of these cells in mammals is that they express the Reelin gene.


go_id: GO:0021871
term: forebrain regionalization
ontology: BP
definition:
The regionalization process resulting in the creation of areas within the forebrain that will direct the behavior of cell migration in differentiation as the forebrain develops.


go_id: GO:0021872
term: forebrain generation of neurons
ontology: BP
definition:
The process in which nerve cells are generated in the forebrain. This includes the production of neuroblasts from and their differentiation into neurons.


go_id: GO:0021873
term: forebrain neuroblast division
ontology: BP
definition:
The division of a neuroblast located in the forebrain. Neuroblast division gives rise to at least another neuroblast.


go_id: GO:0021874
term: Wnt signaling pathway involved in forebrain neuroblast division
ontology: BP
definition:
The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell that contributes to the self renewal of neuroblasts in the forebrain.


go_id: GO:0021875
term: fibroblast growth factor receptor signaling pathway involved in forebrain neuroblast division
ontology: BP
definition:
The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to the self renewal of neuroblasts in the forebrain.


go_id: GO:0021876
term: Notch signaling pathway involved in forebrain neuroblast division
ontology: BP
definition:
The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to the self renewal of neuroblasts in the forebrain.


go_id: GO:0021877
term: forebrain neuron fate commitment
ontology: BP
definition:
The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron that resides in the forebrain.


go_id: GO:0021878
term: forebrain astrocyte fate commitment
ontology: BP
definition:
The process in which the developmental fate of a cell becomes restricted such that it will develop into an astrocyte that resides in the forebrain.


go_id: GO:0021879
term: forebrain neuron differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a neuron that will reside in the forebrain.


go_id: GO:0021880
term: Notch signaling pathway involved in forebrain neuron fate commitment
ontology: BP
definition:
The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain.


go_id: GO:0021881
term: Wnt-activated signaling pathway involved in forebrain neuron fate commitment
ontology: BP
definition:
The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell that contributes to the commitment of a neuroblast to aneuronal fate. The neuron will reside in the forebrain.


go_id: GO:0021884
term: forebrain neuron development
ontology: BP
definition:
The process whose specific outcome is the progression of a neuron that resides in the forebrain, from its initial commitment to its fate, to the fully functional differentiated cell.


go_id: GO:0021885
term: forebrain cell migration
ontology: BP
definition:
The orderly movement of a cell from one site to another at least one of which is located in the forebrain.


go_id: GO:0021886
term: hypothalamus gonadotrophin-releasing hormone neuron differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a neuron located in the hypothalamus. These neurons release gonadotrophin-releasing hormone as a neural transmitter.


go_id: GO:0021887
term: hypothalamus gonadotrophin-releasing hormone neuron fate commitment
ontology: BP
definition:
The process in which the developmental fate of a cell becomes restricted such that it will develop into a hypothalamus neuron that releases gonadotrophin-releasing hormone.


go_id: GO:0021888
term: hypothalamus gonadotrophin-releasing hormone neuron development
ontology: BP
definition:
The process whose specific outcome is the progression of a hypothalamus gonadotrophin-releasing hormone neuron over time, from initial commitment of its fate, to the fully functional differentiated cell.


go_id: GO:0021889
term: olfactory bulb interneuron differentiation
ontology: BP
definition:
The process in which a neuroblast acquires specialized features of an interneuron residing in the olfactory bulb.


go_id: GO:0021890
term: olfactory bulb interneuron fate commitment
ontology: BP
definition:
The process in which the developmental fate of a neuroblast becomes restricted such that it will develop into an interneuron residing in the olfactory bulb.


go_id: GO:0021891
term: olfactory bulb interneuron development
ontology: BP
definition:
The process whose specific outcome is the progression of an interneuron residing in the olfactory bulb, from its initial commitment, to the fully functional differentiated cell.


go_id: GO:0021892
term: cerebral cortex GABAergic interneuron differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a GABAergic interneuron residing in the cerebral cortex.


go_id: GO:0021893
term: cerebral cortex GABAergic interneuron fate commitment
ontology: BP
definition:
The process in which the developmental fate of a neuroblast becomes restricted such that it will develop into a GABAergic interneuron residing in the cerebral cortex.


go_id: GO:0021894
term: cerebral cortex GABAergic interneuron development
ontology: BP
definition:
The process whose specific outcome is the progression of a cerebral cortex GABAergic interneuron over time, from initial commitment to its fate, to the fully functional differentiated cell.


go_id: GO:0021895
term: cerebral cortex neuron differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a neuron residing in the cerebral cortex.


go_id: GO:0021896
term: forebrain astrocyte differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte residing in the forebrain. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function.


go_id: GO:0021897
term: forebrain astrocyte development
ontology: BP
definition:
The process aimed at the progression of an astrocyte that resides in the forebrain, from initial commitment of the cell to its fate, to the fully functional differentiated cell. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function.


go_id: GO:0021898
term: commitment of multipotent stem cells to neuronal lineage in forebrain
ontology: BP
definition:
The initial commitment of cells whereby the developmental fate of a cell becomes restricted such that it will develop into some type of neuron in the forebrain.


go_id: GO:0021899
term: fibroblast growth factor receptor signaling pathway involved in forebrain neuron fate commitment
ontology: BP
definition:
The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain.


go_id: GO:0021900
term: ventricular zone cell fate commitment
ontology: BP
definition:
The commitment of neuroblast to become a basal progenitor cell. Basal progenitor cells are neuronal precursor cells that are committed to becoming neurons.


go_id: GO:0021907
ontology: BP
term:
fibroblast growth factor receptor signaling pathway involved in spinal cord anterior/posterior pattern formation

definition:
The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that results in the spatial identity of regions along the anterior-posterior axis of the spinal cord.


go_id: GO:0021908
ontology: BP
term:
retinoic acid receptor signaling pathway involved in spinal cord anterior/posterior pattern formation

definition:
The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that results in the spatial identity of regions along the anterior-posterior axis of the spinal cord.


go_id: GO:0021910
term: smoothened signaling pathway involved in ventral spinal cord patterning
ontology: BP
definition:
The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened that results in the spatial identity of regions along the dorsal-ventral axis of the spinal cord.


go_id: GO:0021911
term: retinoic acid metabolic process in spinal cord anterior-posterior patterning
ontology: BP
definition:
The chemical reactions and pathways involving the synthesis and degradation of retionic acid that results in the spatial identity of regions along the anterior-posterior axis of the spinal cord.


go_id: GO:0021914
term: negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of smoothened signaling that is involved in the patterns of cell differentiation in the ventral spinal cord.


go_id: GO:0021915
term: neural tube development
ontology: BP
definition:
The process whose specific outcome is the progression of the neural tube over time, from its formation to the mature structure. The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium.


go_id: GO:0021916
term: inductive cell-cell signaling between paraxial mesoderm and motor neuron precursors
ontology: BP
definition:
Short range signaling between cells of the paraxial mesoderm and motor neuron precursors in the spinal cord that specifies the fate of the motor column neuron precursors along the anterior-posterior axis.


go_id: GO:0021917
term: somatic motor neuron fate commitment
ontology: BP
definition:
The commitment of unspecified motor neurons to specific motor neuron cell along the anterior-posterior axis of the spinal cord and their capacity to differentiate into specific motor neurons.


go_id: GO:0021919
term: BMP signaling pathway involved in spinal cord dorsal/ventral patterning
ontology: BP
definition:
The series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the spatial identity of regions along the dorsal-ventral axis of the spinal cord.


go_id: GO:0021921
term: regulation of cell proliferation in dorsal spinal cord
ontology: BP
definition:
The process that modulates the frequency, rate or extent of cell proliferation in the dorsal spinal cord.


go_id: GO:0021922
term: Wnt signaling pathway involved in regulation of cell proliferation in dorsal spinal cord
ontology: BP
definition:
The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of a cell in the dorsal spinal cord that affects the rate of its division.


go_id: GO:0021923
term: cell proliferation in hindbrain ventricular zone
ontology: BP
definition:
The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain region that is adjacent to the ventricular cavity.


go_id: GO:0021924
term: cell proliferation in external granule layer
ontology: BP
definition:
The multiplication or reproduction of neuroblasts resulting in the expansion of a cell population in the external granule layer of the hindbrain. The external granule layer is the layer that originates from the rostral half of the rhombic lip in the first rhombomere.


go_id: GO:0021925
term: cerebellar Purkinje cell precursor proliferation
ontology: BP
definition:
The multiplication or reproduction of neuroblasts that will give rise to Purkinje cells. A Purkinje cell is an inhibitory GABAergic neuron found in the cerebellar cortex that projects to the deep cerebellar nuclei and brain stem.


go_id: GO:0021926
term: Golgi cell precursor proliferation
ontology: BP
definition:
The multiplication or reproduction of neuroblasts that will give rise to Golgi cells. A Golgi cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.


go_id: GO:0021928
term: basket cell precursor proliferation
ontology: BP
definition:
The multiplication or reproduction of neuroblasts that will give rise to basket cells. A cerebellar basket cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.


go_id: GO:0021929
term: stellate cell precursor proliferation
ontology: BP
definition:
The multiplication or reproduction of neuroblasts that will give rise to stellate cells. A cerebellar stellate cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.


go_id: GO:0021930
term: cerebellar granule cell precursor proliferation
ontology: BP
definition:
The multiplication or reproduction of neuroblasts that will give rise to granule cells. A granule cell is a glutamatergic interneuron found in the cerebellar cortex.


go_id: GO:0021931
term: rostral hindbrain neuronal precursor cell proliferation
ontology: BP
definition:
The multiplication or reproduction of neuroblasts that will give rise to neurons of the lateral pontine nucleus and the locus ceruleus.


go_id: GO:0021932
term: hindbrain radial glia guided cell migration
ontology: BP
definition:
The radially directed movement of a cell along radial glial cells in the hindbrain. Radial migration refers to a directed movement from the internal ventricular area to the outer surface of the hindbrain.


go_id: GO:0021933
term: radial glia guided migration of cerebellar granule cell
ontology: BP
definition:
The inward migration of postmitotic granule cells along a radial glial cell from the external granule layer to the internal granule cell layer.


go_id: GO:0021934
term: hindbrain tangential cell migration
ontology: BP
definition:
The migration of a cell in the hindbrain in which cells move orthogonal to the direction of radial migration.


go_id: GO:0021935
term: cerebellar granule cell precursor tangential migration
ontology: BP
definition:
The early migration of granule cell precursors in which cells move orthogonal to the direction of radial migration and ultimately cover the superficial zone of the cerebellar primordium.


go_id: GO:0021937
ontology: BP
term:
cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation

definition:
The process that mediates the transfer of information from Purkinje cells to granule cell precursors resulting in an increase in rate of granule cell precursor cell proliferation.


go_id: GO:0021938
ontology: BP
term:
smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation

definition:
The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened in cerebellar granule cells that contributes to the regulation of proliferation of the cells.


go_id: GO:0021939
ontology: BP
term:
extracellular matrix-granule cell signaling involved in regulation of granule cell precursor proliferation

definition:
The process that mediates the transfer of information from the extracellular matrix to granule cell precursors resulting in a decrease in rate of granule cell precursor cell proliferation.


go_id: GO:0021941
term: negative regulation of cerebellar granule cell precursor proliferation
ontology: BP
definition:
The process that stops, prevents or reduces the rate or extent of granule cell precursor proliferation.


go_id: GO:0021942
term: radial glia guided migration of Purkinje cell
ontology: BP
definition:
The migration of postmitotic a Purkinje cell along radial glial cells from the ventricular zone to the Purkinje cell layer.


go_id: GO:0021943
term: formation of radial glial scaffolds
ontology: BP
definition:
The formation of scaffolds from a radial glial cell. The scaffolds are used as a substrate for the radial migration of cells.


go_id: GO:0021944
term: neuronal-glial interaction involved in hindbrain glial-mediated radial cell migration
ontology: BP
definition:
The changes in adhesion between a neuronal cell and a glial cell as a component of the process of hindbrain glial-mediated radial cell migration.


go_id: GO:0021945
term: positive regulation of cerebellar granule cell migration by calcium
ontology: BP
definition:
The process that increases the extent of granule cell motility using intracellular calcium signaling mechanisms during radial migration.


go_id: GO:0021946
term: deep nuclear neuron cell migration
ontology: BP
definition:
The directed movement of a deep nuclear neuron from the ventricular zone to the deep hindbrain nuclei.


go_id: GO:0021947
term: outward migration of deep nuclear neurons
ontology: BP
definition:
The directed movement of a deep nuclear neuron from their ventrolateral origin to a rostrodorsal region of the cerebellar plate.


go_id: GO:0021948
term: inward migration of deep nuclear neurons
ontology: BP
definition:
The directed movement of a deep nuclear neuron from the rostrodorsal region of the cerebellar plate to their final more ventral position.


go_id: GO:0021949
term: brainstem precerebellar neuron precursor migration
ontology: BP
definition:
The early migration of a precerebellar neuronal precursor in which a cell move from the rhombic lip, orthogonal to the direction of radial migration and ultimately reside in the brainstem.


go_id: GO:0021950
term: chemorepulsion involved in precerebellar neuron migration
ontology: BP
definition:
The creation and reception of signals that repel a precerebellar neuron as a component of the process of tangential migration.


go_id: GO:0021951
term: chemoattraction involved in precerebellar neuron migration
ontology: BP
definition:
The creation and reception of signals that guide a precerebellar neuron towards their signals, where this process is involved in tangential migration.


go_id: GO:0021952
term: central nervous system projection neuron axonogenesis
ontology: BP
definition:
Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells in a different central nervous system region.


go_id: GO:0021953
term: central nervous system neuron differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the central nervous system.


go_id: GO:0021954
term: central nervous system neuron development
ontology: BP
definition:
The process whose specific outcome is the progression of a neuron whose cell body is located in the central nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron.


go_id: GO:0021955
term: central nervous system neuron axonogenesis
ontology: BP
definition:
Generation of a long process from a neuron whose cell body resides in the central nervous system. The process carries efferent (outgoing) action potentials from the cell body towards target cells.


go_id: GO:0021956
term: central nervous system interneuron axonogenesis
ontology: BP
definition:
Generation of a long process that carries efferent (outgoing) action potentials from the cell body towards target cells from a neuron located in the central nervous system whose axons remain within a single brain region.


go_id: GO:0021957
term: corticospinal tract morphogenesis
ontology: BP
definition:
Generation of a long process of a pyramidal cell, that carries efferent (outgoing) action potentials from the cell body in cerebral cortex layer V towards target cells in the gray matter of the spinal cord. This axonal process is a member of those that make up the corticospinal tract.


go_id: GO:0021958
term: gracilis tract morphogenesis
ontology: BP
definition:
Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the dorsal root ganglion towards target cells in the medulla. This axonal process is a member of those that make up the gracilis tract, a group of axons that are from neurons involved in proprioception from the lower trunk and lower limb.


go_id: GO:0021959
term: cuneatus tract morphogenesis
ontology: BP
definition:
Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the dorsal root ganglion towards target cells in the medulla. This axonal process is a member of those that make up the cuneatus tract, a group of axons that are from neurons involved in proprioception from the upper trunk and upper limb.


go_id: GO:0021960
term: anterior commissure morphogenesis
ontology: BP
definition:
Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in one half of the cerebral cortex towards target cells in the contralateral half. This axonal process is a member of those that make up the anterior commissure, a small midline fiber tract that lies at the anterior end of the corpus callosum.


go_id: GO:0021961
term: posterior commissure morphogenesis
ontology: BP
definition:
Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the midbrain towards target cells in the diencephalon.


go_id: GO:0021962
term: vestibulospinal tract morphogenesis
ontology: BP
definition:
Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the vestibular nucleus of the pons towards target cells in the spinal cord.


go_id: GO:0021963
term: spinothalamic tract morphogenesis
ontology: BP
definition:
Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the spinal cord towards target cells in the thalamus. This axonal process is a member of those that make up the spinothalamic tract, one of the major routes of nociceptive signaling.


go_id: GO:0021964
term: rubrospinal tract morphogenesis
ontology: BP
definition:
Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the red nucleus of the midbrain towards target cells in the spinal cord.


go_id: GO:0021965
term: spinal cord ventral commissure morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the spinal cord ventral commissure are generated and organized.


go_id: GO:0021966
term: corticospinal neuron axon guidance
ontology: BP
definition:
The process in which the migration of an axon growth cone of a neuron that is part of the corticospinal tract is directed from the cerebral cortex layer V to the spinal cord dorsal funiculus in response to a combination of attractive and repulsive cues.


go_id: GO:0021967
term: corticospinal neuron axon guidance through the cerebral cortex
ontology: BP
definition:
The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed from its cell body in layer V through the cerebral cortex in response to a combination of attractive and repulsive cues.


go_id: GO:0021968
term: corticospinal neuron axon guidance through the internal capsule
ontology: BP
definition:
The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the cerebral cortex through the internal capsule in response to a combination of attractive and repulsive cues.


go_id: GO:0021969
term: corticospinal neuron axon guidance through the cerebral peduncle
ontology: BP
definition:
The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the internal capsule through the cerebral peduncle in response to a combination of attractive and repulsive cues.


go_id: GO:0021970
term: corticospinal neuron axon guidance through the basilar pons
ontology: BP
definition:
The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the cerebral peduncle through the basilar pons in response to a combination of attractive and repulsive cues.


go_id: GO:0021971
term: corticospinal neuron axon guidance through the medullary pyramid
ontology: BP
definition:
The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the basilar pons through the medullary pyramid in response to a combination of attractive and repulsive cues.


go_id: GO:0021972
term: corticospinal neuron axon guidance through spinal cord
ontology: BP
definition:
The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after decussation through the spinal cord in response to a combination of attractive and repulsive cues.


go_id: GO:0021973
term: corticospinal neuron axon decussation
ontology: BP
definition:
The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed to cross the midline to the contralateral side.


go_id: GO:0021974
term: trigeminothalamic tract morphogenesis
ontology: BP
definition:
Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in spinal cord towards target cells in the thalamus. This axonal process is a member of those that make up the trigeminothalamic tract, one of the major routes of nociceptive and temperature signaling from the face.


go_id: GO:0021975
term: pons reticulospinal tract morphogenesis
ontology: BP
definition:
Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the pons towards target cells in the spinal cord.


go_id: GO:0021976
term: medulla reticulospinal tract morphogenesis
ontology: BP
definition:
Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the medulla towards target cells in the spinal cord.


go_id: GO:0021977
term: tectospinal tract morphogenesis
ontology: BP
definition:
Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the superior colliculus of the midbrain towards target cells in the ventral spinal cord.


go_id: GO:0021978
term: telencephalon regionalization
ontology: BP
definition:
The regionalization process that creates areas within the forebrain that will direct the behavior of cell migration in differentiation as the telencephalon develops.


go_id: GO:0021979
term: hypothalamus cell differentiation
ontology: BP
definition:
The differentiation of cells that will contribute to the structure and function of the hypothalamus.


go_id: GO:0021981
term: subpallium radially oriented migration
ontology: BP
definition:
The migration of cells in the developing subpallium in which cells move from the ventricular and/or subventricular zone toward the surface of the brain.


go_id: GO:0021982
term: pineal gland development
ontology: BP
definition:
The progression of the pineal gland over time from its initial formation until its mature state. The pineal gland is an endocrine gland that secretes melatonin and is involved in circadian rhythms.


go_id: GO:0021983
term: pituitary gland development
ontology: BP
definition:
The progression of the pituitary gland over time from its initial formation until its mature state. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands.


go_id: GO:0021984
term: adenohypophysis development
ontology: BP
definition:
The progression of the adenohypophysis over time from its initial formation until its mature state. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus.


go_id: GO:0021985
term: neurohypophysis development
ontology: BP
definition:
The progression of the neurohypophysis over time from its initial formation until its mature state. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation.


go_id: GO:0021986
term: habenula development
ontology: BP
definition:
The progression of the habenula over time from its initial formation until its mature state. The habenula is the group of nuclei that makes up the stalk of the pineal gland.


go_id: GO:0021987
term: cerebral cortex development
ontology: BP
definition:
The progression of the cerebral cortex over time from its initial formation until its mature state. The cerebral cortex is the outer layered region of the telencephalon.


go_id: GO:0021988
term: olfactory lobe development
ontology: BP
definition:
The progression of the olfactory lobe over time from its initial formation until its mature state. The olfactory lobe is the area of the brain that process the neural inputs for the sense of smell.


go_id: GO:0021989
term: olfactory cortex development
ontology: BP
definition:
The progression of the olfactory cortex over time from its initial formation until its mature state. The olfactory cortex is involved in the perception of smell. It receives input from the olfactory bulb and is responsible for the identification of odors.


go_id: GO:0021990
term: neural plate formation
ontology: BP
definition:
The formation of the flat, thickened layer of ectodermal cells known as the neural plate. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system.


go_id: GO:0021991
term: neural plate thickening
ontology: BP
definition:
The process of apical-basal elongation of individual ectodermal cells during the formation of the neural placode.


go_id: GO:0021992
term: cell proliferation involved in neural plate elongation
ontology: BP
definition:
The process of expansion of cell numbers in the neural plate due to cell division of progenitor cells preferentially in the rostrocaudal direction, resulting in the elongation of the tissue.


go_id: GO:0021993
term: initiation of neural tube closure
ontology: BP
definition:
The process in which closure points are established at multiple points and along the neural rostrocaudal axis.


go_id: GO:0021996
term: lamina terminalis formation
ontology: BP
definition:
The process in which the anterior-most portion of the neural axis is formed by closure of the anterior neuropore.


go_id: GO:0021998
term: neural plate mediolateral regionalization
ontology: BP
definition:
The process that regulates the coordinated growth and differentiation that establishes the non-random mediolateral spatial arrangement of the neural plate.


go_id: GO:0021999
term: neural plate anterior/posterior regionalization
ontology: BP
definition:
The process that regulates the coordinated growth and differentiation that establishes the non-random anterior-posterior spatial arrangement of the neural plate.


go_id: GO:0022000
term: forebrain induction by the anterior neural ridge
ontology: BP
definition:
The close range interaction of the anterior neural ridge to the caudal region of the neural plate that specifies the forebrain fate.


go_id: GO:0022001
term: negative regulation of anterior neural cell fate commitment of the neural plate
ontology: BP
definition:
Any process that stops, prevents or reduces the frequency or rate at which a cell adopts an anterior neural cell fate.


go_id: GO:0022002
ontology: BP
term:
negative regulation of anterior neural cell fate commitment of the neural plate by Wnt signaling pathway

definition:
The series of molecular signals that stops, prevents or reduces the frequency or rate at which a cell adopts an anterior neural cell fate, initiated by binding of Wnt protein to a receptor on the surface of the target cell.


go_id: GO:0022003
ontology: BP
term:
negative regulation of anterior neural cell fate commitment of the neural plate by fibroblast growth factor receptor signaling pathway

definition:
The series of molecular signals that stops, prevents or reduces the frequency or rate at which cell adopts an anterior neural cell fate, generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands.


go_id: GO:0022004
term: midbrain-hindbrain boundary maturation during brain development
ontology: BP
definition:
A developmental process occurring after the brain has been specified along the neural axis that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.


go_id: GO:0022005
term: midbrain-hindbrain boundary maturation during neural plate development
ontology: BP
definition:
A developmental process occurring before the brain has been specified along the neural axis that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.


go_id: GO:0022006
term: zona limitans intrathalamica formation
ontology: BP
definition:
The formation of the narrow stripe of cells that lies between the prospective dorsal and ventral thalami. This boundary contains signals that pattern the prethalamic and thalamic territories of the future mid-diencephalon.


go_id: GO:0022007
term: convergent extension involved in neural plate elongation
ontology: BP
definition:
The process of directed cell movement in the neural plate resulting in tissue elongation via intercalation of adjacent cells in an epithelial sheet at the midline, leading to narrowing and lengthening of the neural plate.


go_id: GO:0022009
term: central nervous system vasculogenesis
ontology: BP
definition:
The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes in the central nervous system. The capillary endothelial cells in the brain are specialized to form the blood-brain barrier.


go_id: GO:0022010
term: central nervous system myelination
ontology: BP
definition:
The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of oligodendrocytes in the central nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.


go_id: GO:0022011
term: myelination in peripheral nervous system
ontology: BP
definition:
The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of Schwann cells in the peripheral nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.


go_id: GO:0022012
term: subpallium cell proliferation in forebrain
ontology: BP
definition:
The multiplication or reproduction of subpallium cells in the forebrain, resulting in the expansion of a cell population.


go_id: GO:0022013
term: pallium cell proliferation in forebrain
ontology: BP
definition:
The multiplication or reproduction of pallium cells in the forebrain, resulting in the expansion of the cell population.


go_id: GO:0022015
term: radial glial cell division in pallium
ontology: BP
definition:
The division of a radial glial cell in the pallium. A radial glial cell is a precursor cell that gives rise to neurons and astrocytes.


go_id: GO:0022016
term: pallium glioblast division
ontology: BP
definition:
The division of a glioblast in the pallium. A glioblast is a dividing precursor cell that gives rise to glial cells.


go_id: GO:0022017
term: neuroblast division in pallium
ontology: BP
definition:
The division of neuroblasts in the pallium. Neuroblasts are precursor cells that give rise to neurons.


go_id: GO:0022018
term: lateral ganglionic eminence cell proliferation
ontology: BP
definition:
The multiplication or reproduction of lateral ganglionic eminence cells, resulting in the expansion of the cell population.


go_id: GO:0022019
term: dorsal lateral ganglionic eminence cell proliferation
ontology: BP
definition:
The multiplication or reproduction of dorsal lateral ganglionic eminence cells, resulting in the expansion of the cell population.


go_id: GO:0022020
term: medial ganglionic eminence cell proliferation
ontology: BP
definition:
The multiplication or reproduction of medial ganglionic eminence cells, resulting in the expansion of a cell population.


go_id: GO:0022021
term: caudal ganglionic eminence cell proliferation
ontology: BP
definition:
The multiplication or reproduction of caudal ganglionic eminence cells, resulting in the expansion of a cell population.


go_id: GO:0022022
term: septal cell proliferation
ontology: BP
definition:
The multiplication or reproduction of septal cells, resulting in the expansion of a cell population.


go_id: GO:0022023
term: radial glial cell fate commitment in forebrain
ontology: BP
definition:
The process in which the developmental fate of a cell becomes restricted such that it will develop into a radial glial cell in the forebrain.


go_id: GO:0022024
term: BMP signaling pathway involved in forebrain neuron fate commitment
ontology: BP
definition:
The series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain.


go_id: GO:0022025
term: leukemia inhibitory factor signaling pathway involved in forebrain neuron fate commitment
ontology: BP
definition:
The series of molecular signals initiated by the binding of leukemia inhibitory factor to its receptor on the surface of the target cell, that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain.


go_id: GO:0022026
term: epidermal growth factor signaling pathway involved in forebrain neuron fate commitment
ontology: BP
definition:
The series of molecular signals generated as a consequence of a epidermal growth factor receptor binding to one of its physiological ligands that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain.


go_id: GO:0022027
term: interkinetic nuclear migration
ontology: BP
definition:
The movement of the nucleus of the ventricular zone cell between the apical and the basal zone surfaces. Mitosis occurs when the nucleus is near the apical surface, that is, the lumen of the ventricle.


go_id: GO:0022028
term: tangential migration from the subventricular zone to the olfactory bulb
ontology: BP
definition:
The migration of cells in the telencephalon from the subventricular zone to the olfactory bulb in which cells move orthogonally to the direction of radial migration and do not use radial glial cell processes as substrates for migration.


go_id: GO:0022029
term: telencephalon cell migration
ontology: BP
definition:
The orderly movement of a cell from one site to another at least one of which is located in the telencephalon.


go_id: GO:0022032
term: telencephalon oligodendrocyte cell migration
ontology: BP
definition:
The multiplication or reproduction of telencephalon oligodendrocyte cells, resulting in the expansion of a cell population.


go_id: GO:0022034
term: rhombomere cell proliferation
ontology: BP
definition:
The multiplication or reproduction of rhombomere cells, resulting in the expansion of the cell population.


go_id: GO:0022035
term: rhombomere cell migration
ontology: BP
definition:
The movement of a cell within a rhombomere. This process is known to occur as an early step in the generation of anatomical structure from a rhombomere.


go_id: GO:0022036
term: rhombomere cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a rhombomere cell.


go_id: GO:0022037
term: metencephalon development
ontology: BP
definition:
The process whose specific outcome is the progression of the metencephalon over time, from its formation to the mature structure.


go_id: GO:0022038
term: corpus callosum development
ontology: BP
definition:
The process whose specific outcome is the progression of the corpus callosum over time, from its formation to the mature structure. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provide communication between the right and left cerebral hemispheres.


go_id: GO:0022401
term: negative adaptation of signaling pathway
ontology: BP
definition:
The negative regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus.


go_id: GO:0022402
term: cell cycle process
ontology: BP
definition:
The cellular process that ensures successive accurate and complete genome replication and chromosome segregation.


go_id: GO:0022403
term: cell cycle phase
ontology: BP
definition:
One of the distinct periods or stages into which the cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events.


go_id: GO:0022404
term: molting cycle process
ontology: BP
definition:
A multicellular organismal process involved in the periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin.


go_id: GO:0022405
term: hair cycle process
ontology: BP
definition:
A multicellular organismal process involved in the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body.


go_id: GO:0022406
term: membrane docking
ontology: BP
definition:
The initial attachment of a membrane or protein to a target membrane. Docking requires only that the proteins come close enough to interact and adhere.


go_id: GO:0022410
term: circadian sleep/wake cycle process
ontology: BP
definition:
A behavioral process involved in the cycle from wakefulness through an orderly succession of sleep states and stages that occurs on an approximately 24 hour rhythm.


go_id: GO:0022412
term: cellular process involved in reproduction in multicellular organism
ontology: BP
definition:
A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular organism.


go_id: GO:0022413
term: reproductive process in single-celled organism
ontology: BP
definition:
A process, occurring at the cellular level, that is involved in the reproductive function of a single-celled organism.


go_id: GO:0022414
term: reproductive process
ontology: BP
definition:
A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents.


go_id: GO:0022416
term: chaeta development
ontology: BP
definition:
The process whose specific outcome is the progression of a chaeta over time, from its formation to the mature structure. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell.


go_id: GO:0022417
term: protein maturation by protein folding
ontology: BP
definition:
The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that results in the attainment of the full functional capacity of a protein.


go_id: GO:0022600
term: digestive system process
ontology: BP
definition:
A physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.


go_id: GO:0022601
term: menstrual cycle phase
ontology: BP
definition:
The progression of physiological phases, occurring in the endometrium during the menstrual cycle that recur at regular intervals during the reproductive years. The menstrual cycle is an ovulation cycle where the endometrium is shed if pregnancy does not occur.


go_id: GO:0022602
term: ovulation cycle process
ontology: BP
definition:
A process involved in the sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years.


go_id: GO:0022604
term: regulation of cell morphogenesis
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process in which the shape of a cell is generated and organized.


go_id: GO:0022605
term: mammalian oogenesis stage
ontology: BP
definition:
A reproductive process that is a step in the formation and maturation of an ovum or female gamete from a primordial female germ cell.


go_id: GO:0022611
term: dormancy process
ontology: BP
definition:
A developmental process in which dormancy (sometimes called a dormant state) is induced, maintained or broken. Dormancy is a suspension of most physiological activity and growth that can be reactivated.


go_id: GO:0022613
term: ribonucleoprotein complex biogenesis
ontology: BP
definition:
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a complex containing RNA and proteins. Includes the biosynthesis of the constituent RNA and protein molecules, and those macromolecular modifications that are involved in synthesis or assembly of the ribonucleoprotein complex.


go_id: GO:0022614
term: membrane to membrane docking
ontology: BP
definition:
The initial attachment of a membrane to a target membrane, mediated by proteins protruding from the two membranes. Docking requires only that the membranes come close enough for the proteins to interact and adhere.


go_id: GO:0022615
term: protein to membrane docking
ontology: BP
definition:
The initial attachment of a protein to a target membrane, mediated by a proteins protruding from the target membrane. Docking requires only that the proteins come close enough to interact and adhere.


go_id: GO:0022616
term: DNA strand elongation
ontology: BP
definition:
The DNA metabolic process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand.


go_id: GO:0022618
term: ribonucleoprotein complex assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex.


go_id: GO:0022619
term: generative cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a generative cell. The generative cell gives rise to the sperm cells in the male gametophyte.


go_id: GO:0022620
term: vegetative cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a vegetative cell. The vegetative cell is gives rise to the pollen tube.


go_id: GO:0022622
term: root system development
ontology: BP
definition:
The process whose specific outcome is the progression of the root system over time, from its formation to the mature structure.


go_id: GO:0022623
term: proteasome-activating nucleotidase complex
ontology: CC
definition:
A homohexameric complex that recognizes and unfolds core proteasome substrate proteins, and translocates them to the core complex in an ATP dependent manner.


go_id: GO:0022624
term: proteasome accessory complex
ontology: CC
definition:
A protein complex, that caps one or both ends of the proteasome core complex and regulates entry into, or exit from, the proteasome core complex.


go_id: GO:0022803
term: passive transmembrane transporter activity
ontology: MF
definition:
Enables the transfer of a single solute from one side of a membrane to the other by a mechanism involving conformational change, either by facilitated diffusion or in a membrane potential dependent process if the solute is charged.


go_id: GO:0022804
term: active transmembrane transporter activity
ontology: MF
definition:
Enables the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.


go_id: GO:0022809
term: mobile ion carrier activity
ontology: MF
definition:
Small molecule produced by bacteria that carries an ion across the membrane by enclosing the ion and travelling with the ion across the membrane. It does not form a fully open pore across the membrane.


go_id: GO:0022810
term: membrane potential driven uniporter activity
ontology: MF
definition:
Enables the active transport of a solute across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged.


go_id: GO:0022818
term: sodium ion uniporter activity
ontology: MF
definition:
Catalysis of the active transport of a sodium ion across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged.


go_id: GO:0022819
term: potassium ion uniporter activity
ontology: MF
definition:
Catalysis of the active transport of a potassium ion across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged.


go_id: GO:0022821
term: solute:potassium antiporter activity
ontology: MF
definition:
Catalysis of the active transport of a potassium ion across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.


go_id: GO:0022824
term: transmitter-gated ion channel activity
ontology: MF
definition:
Enables the transmembrane transfer of an ion by a channel that opens when a specific neurotransmitter has been bound by the channel complex or one of its constituent parts.


go_id: GO:0022828
term: phosphorylation-gated channel activity
ontology: MF
definition:
Enables the transmembrane transfer of a solute by a channel that opens in response to phosphorylation of one of its constituent parts.


go_id: GO:0022829
term: wide pore channel activity
ontology: MF
definition:
Enables the transport of a solute across a membrane via a large pore, un-gated channel. Examples include gap junctions, which transport substances from one cell to another; and porins which transport substances in and out of bacteria, mitochondria and chloroplasts.


go_id: GO:0022831
term: narrow pore, gated channel activity
ontology: MF
definition:
Enables the transport of a solute across a membrane via a narrow pore channel that opens in response to a particular stimulus.


go_id: GO:0022832
term: voltage-gated channel activity
ontology: MF
definition:
Enables the transmembrane transfer of a solute by a channel whose open state is dependent on the voltage across the membrane in which it is embedded.


go_id: GO:0022834
term: ligand-gated channel activity
ontology: MF
definition:
Enables the transmembrane transfer of a solute by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.


go_id: GO:0022835
term: transmitter-gated channel activity
ontology: MF
definition:
Enables the transmembrane transfer of a solute by a channel that opens when a specific neurotransmitter has been bound by the channel complex or one of its constituent parts.


go_id: GO:0022836
term: gated channel activity
ontology: MF
definition:
Enables the transmembrane transfer of a solute by a channel that opens in response to a specific stimulus.


go_id: GO:0022839
term: ion gated channel activity
ontology: MF
definition:
Enables the transmembrane transfer of a solute by a channel that opens in response to a specific ion stimulus.


go_id: GO:0022840
term: leak channel activity
ontology: MF
definition:
Enables the transport of a solute across a membrane via a narrow pore channel that is open even in an unstimulated or 'resting' state.


go_id: GO:0022841
term: potassium ion leak channel activity
ontology: MF
definition:
Enables the transport of a potassium ion across a membrane via a narrow pore channel that is open even in an unstimulated or 'resting' state.


go_id: GO:0022842
term: narrow pore channel activity
ontology: MF
definition:
Enables the transport of a solute across a membrane via a narrow pore channel that may be gated or ungated.


go_id: GO:0022843
term: voltage-gated cation channel activity
ontology: MF
definition:
Enables the transmembrane transfer of a cation by a voltage-gated channel. A cation is a positively charged ion. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.


go_id: GO:0022848
term: acetylcholine-gated cation-selective channel activity
ontology: MF
definition:
Selectively enables the transmembrane transfer of a cation by a channel that opens upon binding acetylcholine.


go_id: GO:0022849
term: glutamate-gated calcium ion channel activity
ontology: MF
definition:
Enables the transmembrane transfer of a calcium ion by a channel that opens when glutamate has been bound by the channel complex or one of its constituent parts.


go_id: GO:0022850
term: serotonin-gated cation-selective channel activity
ontology: MF
definition:
Enables the transmembrane transfer of a cation by a channel that opens when serotonin has been bound by the channel complex or one of its constituent parts.


go_id: GO:0022851
term: GABA-gated chloride ion channel activity
ontology: MF
definition:
Enables the transmembrane transfer of a chloride ion by a channel that opens when GABA has been bound by the channel complex or one of its constituent parts.


go_id: GO:0022852
term: glycine-gated chloride ion channel activity
ontology: MF
definition:
Enables the transmembrane transfer of a chloride ion by a channel that opens when glycine has been bound by the channel complex or one of its constituent parts.


go_id: GO:0022853
term: active ion transmembrane transporter activity
ontology: MF
definition:
Enables the transfer of an ion from one side of a membrane to the other up the solute's concentration gradient. This is carried out by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction.


go_id: GO:0022855
term: protein-N(PI)-phosphohistidine-glucose phosphotransferase system transporter activity
ontology: MF
definition:
Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + glucose(out) = protein histidine + glucose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.


go_id: GO:0022856
term: protein-N(PI)-phosphohistidine-sorbitol phosphotransferase system transporter activity
ontology: MF
definition:
Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sorbitol(out) = protein histidine + sorbitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.


go_id: GO:0022857
term: transmembrane transporter activity
ontology: MF
definition:
Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.


go_id: GO:0022858
term: alanine transmembrane transporter activity
ontology: MF
definition:
Enables the transfer of alanine from one side of a membrane to the other. Alanine is 2-aminopropanoic acid.


go_id: GO:0022859
term: dephosphorylation-gated channel activity
ontology: MF
definition:
Enables the transmembrane transfer of a solute by a channel that opens in response to dephosphorylation of one of its constituent parts.


go_id: GO:0022869
term: protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ontology: MF
definition:
Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + lactose(out) = protein histidine + lactose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.


go_id: GO:0022870
term: protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity
ontology: MF
definition:
Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + mannose(out) = protein histidine + mannose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.


go_id: GO:0022871
term: protein-N(PI)-phosphohistidine-sorbose phosphotransferase system transporter activity
ontology: MF
definition:
Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sorbose(out) = protein histidine + sorbose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.


go_id: GO:0022872
ontology: MF
term:
protein-N(PI)-phosphohistidine-mannitol phosphotransferase system transmembrane transporter activity

definition:
Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + mannitol(out) = protein histidine + mannitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.


go_id: GO:0022873
term: protein-N(PI)-phosphohistidine-maltose phosphotransferase system transporter activity
ontology: MF
definition:
Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + maltose(out) = protein histidine + maltose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.


go_id: GO:0022874
term: protein-N(PI)-phosphohistidine-cellobiose phosphotransferase system transporter activity
ontology: MF
definition:
Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + cellobiose(out) = protein histidine + cellobiose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.


go_id: GO:0022875
ontology: MF
term:
protein-N(PI)-phosphohistidine-galactitol phosphotransferase system transmembrane transporter activity

definition:
Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + galactitol(out) = protein histidine + galactitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.


go_id: GO:0022876
term: protein-N(PI)-phosphohistidine-galactosamine phosphotransferase system transporter activity
ontology: MF
definition:
Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + galactosamine(out) = protein histidine + galactosamine phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.


go_id: GO:0022877
term: protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ontology: MF
definition:
Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + fructose(out) = protein histidine + fructose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.


go_id: GO:0022878
term: protein-N(PI)-phosphohistidine-sucrose phosphotransferase system transporter activity
ontology: MF
definition:
Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sucrose(out) = protein histidine + sucrose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.


go_id: GO:0022879
term: protein-N(PI)-phosphohistidine-trehalose phosphotransferase system transporter activity
ontology: MF
definition:
Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + trehalose(out) = protein histidine + trehalose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.


go_id: GO:0022880
term: protein-N(PI)-phosphohistidine-N-acetylglucosamine phosphotransferase system transporter activity
ontology: MF
definition:
Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + N-acetylglucosamine(out) = protein histidine + N-acetylglucosamine phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.


go_id: GO:0022881
term: protein-N(PI)-phosphohistidine-N-acetylgalactosamine phosphotransferase system transporter activity
ontology: MF
definition:
Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + N-acetylgalactosamine(out) = protein histidine + N-acetylgalactosamine phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.


go_id: GO:0022882
term: protein-N(PI)-phosphohistidine-beta-glucoside phosphotransferase system transporter activity
ontology: MF
definition:
Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + beta-glucoside(out) = protein histidine + beta-glucoside phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.


go_id: GO:0022883
term: zinc efflux transmembrane transporter activity
ontology: MF
definition:
Enables the transfer of a zinc ion or zinc ions from the inside of the cell to the outside of the cell across a membrane.


go_id: GO:0022886
term: channel-forming ionophore activity
ontology: MF
definition:
Enables transport of a solute across a membrane. This kind of transporter interacts much more weakly with the solute than the carrier does. It is an aqueous pore that extends across the membrane. It may change from closed to open and back. It transports faster than a carrier. It is always passive.


go_id: GO:0022889
term: serine transmembrane transporter activity
ontology: MF
definition:
Enables the transfer of serine from one side of a membrane to the other. Serine is 2-amino-3-hydroxypropanoic acid.


go_id: GO:0022890
term: inorganic cation transmembrane transporter activity
ontology: MF
definition:
Enables the transfer of inorganic cations from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage.


go_id: GO:0022893
term: low-affinity tryptophan transmembrane transporter activity
ontology: MF
definition:
Catalysis of the low-affinity transfer of L-tryptophan from one side of a membrane to the other. Tryptophan is 2-amino-3-(1H-indol-3-yl)propanoic acid. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.


go_id: GO:0022894
term: Intermediate conductance calcium-activated potassium channel activity
ontology: MF
definition:
Enables the transmembrane transfer of potassium by a channel with a unit conductance of 20 to 85 picoSiemens that opens in response to stimulus by internal calcium ions. Intermediate conductance calcium-activated potassium channels are more sensitive to calcium than are large conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism.


go_id: GO:0022897
term: proton-dependent peptide secondary active transmembrane transporter activity
ontology: MF
definition:
Enables the transfer of a peptide from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by proton movement.


go_id: GO:0022900
term: electron transport chain
ontology: BP
definition:
A process in which a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors.


go_id: GO:0022904
term: respiratory electron transport chain
ontology: BP
definition:
A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient.


go_id: GO:0023003
term: nuclear migration to the embryo sac center
ontology: BP
definition:
Migration of one of the four nuclei at each pole of the eight-nucleate embryo sac, to the center of the cell.


go_id: GO:0023019
term: signal transduction involved in regulation of gene expression
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a signal is released and/or conveyed from one location to another.


go_id: GO:0023021
term: termination of signal transduction
ontology: BP
definition:
The signaling process in which signal transduction is brought to an end rather than being reversibly modulated.


go_id: GO:0023022
term: termination of T cell signal transduction
ontology: BP
definition:
The signaling process in which T cell signal transduction is brought to an end rather than being reversibly modulated.


go_id: GO:0023035
term: CD40 signaling pathway
ontology: BP
definition:
The series of molecular signals initiated by the binding of the cell surface receptor CD40 to one of its physiological ligands, and ending with the regulation of a downstream cellular process, e.g. transcription.


go_id: GO:0023041
term: neuronal signal transduction
ontology: BP
definition:
The process in which an activated neuronal cell receptor conveys information down a signaling pathway, resulting in a change in the function or state of a cell. This process may be intracellular or intercellular.


go_id: GO:0023052
term: signaling
ontology: BP
definition:
The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered.


go_id: GO:0023056
term: positive regulation of signaling
ontology: BP
definition:
Any process that activates, maintains or increases the frequency, rate or extent of a signaling process.


go_id: GO:0023058
term: adaptation of signaling pathway
ontology: BP
definition:
The regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus.


go_id: GO:0023059
term: positive adaptation of signaling pathway
ontology: BP
definition:
The positive regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus.


go_id: GO:0023061
term: signal release
ontology: BP
definition:
The process in which a signal is secreted or discharged into the extracellular medium from a cellular source.


go_id: GO:0030001
term: metal ion transport
ontology: BP
definition:
The directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0030002
term: cellular anion homeostasis
ontology: BP
definition:
Any process involved in the maintenance of an internal steady state of anions at the level of a cell.


go_id: GO:0030003
term: cellular cation homeostasis
ontology: BP
definition:
Any process involved in the maintenance of an internal steady state of cations at the level of a cell.


go_id: GO:0030004
term: cellular monovalent inorganic cation homeostasis
ontology: BP
definition:
Any process involved in the maintenance of an internal steady state of monovalent inorganic cations at the level of a cell.


go_id: GO:0030007
term: cellular potassium ion homeostasis
ontology: BP
definition:
Any process involved in the maintenance of an internal steady state of potassium ions at the level of a cell.


go_id: GO:0030008
term: TRAPP complex
ontology: CC
definition:
A large complex that acts as a tethering factor involved in transporting vesicles from the ER through the Golgi to the plasma membrane. A TRAPP (transport protein particle) complex has a core set of proteins which are joined by specific subunits depending on the cellular component where a given TRAPP complex is active.


go_id: GO:0030014
term: CCR4-NOT complex
ontology: CC
definition:
The Ccr4-Not complex is an eukaryotically conserved deadenylase that can initiate cytoplasmic mRNA decay, and reduce translation by releasing poly(A)-binding protein (Pab1/PABPC1). Ccr4-Not contains seven core subunits, including two poly(A)-specific exonucleases, Ccr4/CNOT6/CNOT6L and Caf1/Pop2/CNOT7/CNOT8.


go_id: GO:0030015
term: CCR4-NOT core complex
ontology: CC
definition:
The core of the CCR4-NOT complex. In Saccharomyces the CCR4-NOT core complex comprises Ccr4p, Caf1p, Caf40p, Caf130p, Not1p, Not2p, Not3p, Not4p, and Not5p.


go_id: GO:0030016
term: myofibril
ontology: CC
definition:
The contractile element of skeletal and cardiac muscle; a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism.


go_id: GO:0030017
term: sarcomere
ontology: CC
definition:
The repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.


go_id: GO:0030021
term: extracellular matrix structural constituent conferring compression resistance
ontology: MF
definition:
A constituent of the extracellular matrix that enables the matrix to resist compressive forces; often a proteoglycan.


go_id: GO:0030023
term: extracellular matrix constituent conferring elasticity
ontology: MF
definition:
A component of the extracellular matrix that enables the matrix to recoil after transient stretching.


go_id: GO:0030026
term: cellular manganese ion homeostasis
ontology: BP
definition:
Any process involved in the maintenance of an internal steady state of manganese ions at the level of a cell.


go_id: GO:0030027
term: lamellipodium
ontology: CC
definition:
A thin sheetlike process extended by the leading edge of a migrating cell or extending cell process; contains a dense meshwork of actin filaments.


go_id: GO:0030029
term: actin filament-based process
ontology: BP
definition:
Any cellular process that depends upon or alters the actin cytoskeleton, that part of the cytoskeleton comprising actin filaments and their associated proteins.


go_id: GO:0030030
term: cell projection organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.


go_id: GO:0030033
term: microvillus assembly
ontology: BP
definition:
Formation of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell.


go_id: GO:0030035
term: microspike assembly
ontology: BP
definition:
Formation of a microspike, a dynamic, actin-rich projection extending from the surface of a migrating animal cell.


go_id: GO:0030036
term: actin cytoskeleton organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.


go_id: GO:0030037
term: actin filament reorganization involved in cell cycle
ontology: BP
definition:
The cell cycle process in which rearrangement of the spatial distribution of actin filaments and associated proteins occurs.


go_id: GO:0030038
term: contractile actin filament bundle assembly
ontology: BP
definition:
Assembly of actin filament bundles in which the filaments are loosely packed (approximately 30-60 nm apart) and arranged with opposing polarities; the loose packing allows myosin (usually myosin-II) to enter the bundle.


go_id: GO:0030043
term: actin filament fragmentation
ontology: BP
definition:
The severing of actin filaments into numerous short fragments, usually mediated by actin severing proteins.


go_id: GO:0030046
term: parallel actin filament bundle assembly
ontology: BP
definition:
Assembly of actin filament bundles in which the filaments are tightly packed (approximately 10-20 nm apart) and oriented with the same polarity.


go_id: GO:0030048
term: actin filament-based movement
ontology: BP
definition:
Movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins.


go_id: GO:0030049
term: muscle filament sliding
ontology: BP
definition:
The sliding of actin thin filaments and myosin thick filaments past each other in muscle contraction. This involves a process of interaction of myosin located on a thick filament with actin located on a thin filament. During this process ATP is split and forces are generated.


go_id: GO:0030054
term: cell junction
ontology: CC
definition:
A cellular component that forms a specialized region of connection between two or more cells, or between a cell and the extracellular matrix, or between two membrane-bound components of a cell, such as flagella.


go_id: GO:0030056
term: hemidesmosome
ontology: CC
definition:
A cell-substrate junction (attachment structure) found in epithelial cells that links intermediate filaments to extracellular matrices via transmembrane complexes. In vertebrates, hemidesmosomes mediate contact between the basal side of epithelial cells and the basal lamina. In C. elegans, hemidesmosomes connect epithelial cells to distinct extracellular matrices on both the apical and basal cell surfaces.


go_id: GO:0030057
term: desmosome
ontology: CC
definition:
A cell-cell junction in which: on the cytoplasmic surface of each interacting plasma membrane is a dense plaque composed of a mixture of intracellular anchor proteins; a bundle of keratin intermediate filaments is attached to the surface of each plaque; transmembrane adhesion proteins of the cadherin family bind to the plaques and interact through their extracellular domains to hold the adjacent membranes together by a Ca2+-dependent mechanism.


go_id: GO:0030058
term: amine dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: an aliphatic amine + an acceptor (A) + H2O = an aldehyde + a reduced acceptor (AH2) + NH4+.


go_id: GO:0030059
term: aralkylamine dehydrogenase (azurin) activity
ontology: MF
definition:
Catalysis of the reaction: an aralkylamine + H2O + 2 oxidized [azurin] = an aromatic aldehyde + 2 H+ + NH4+ + 2 reduced [azurin].


go_id: GO:0030061
term: mitochondrial crista
ontology: CC
definition:
Any of the inward folds of the mitochondrial inner membrane. Their number, extent, and shape differ in mitochondria from different tissues and organisms. They appear to be devices for increasing the surface area of the mitochondrial inner membrane, where the enzymes of electron transport and oxidative phosphorylation are found. Their shape can vary with the respiratory state of the mitochondria.


go_id: GO:0030062
term: mitochondrial tricarboxylic acid cycle enzyme complex
ontology: CC
definition:
Any of the heteromeric enzymes, located in the mitochondrion, that act in the tricarboxylic acid (TCA) cycle.


go_id: GO:0030070
term: insulin processing
ontology: BP
definition:
The formation of mature insulin by proteolysis of the precursor preproinsulin. The signal sequence is first cleaved from preproinsulin to form proinsulin; proinsulin is then cleaved to release the C peptide, leaving the A and B chains of mature insulin linked by disulfide bridges.


go_id: GO:0030071
term: regulation of mitotic metaphase/anaphase transition
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.


go_id: GO:0030073
term: insulin secretion
ontology: BP
definition:
The regulated release of proinsulin from secretory granules accompanied by cleavage of proinsulin to form mature insulin. In vertebrates, insulin is secreted from B granules in the B cells of the vertebrate pancreas and from insulin-producing cells in insects.


go_id: GO:0030075
term: bacterial thylakoid
ontology: CC
definition:
A thylakoid that is derived from and attached to, but not necessarily continuous with, the plasma membrane, and is not enclosed in a plastid. It bears the photosynthetic pigments in photosynthetic cyanobacteria.


go_id: GO:0030076
term: light-harvesting complex
ontology: CC
definition:
A protein-pigment complex that may be closely or peripherally associated to photosynthetic reaction centers that participate in harvesting and transferring radiant energy to the reaction center.


go_id: GO:0030077
term: plasma membrane light-harvesting complex
ontology: CC
definition:
A plasma membrane protein-pigment complex that may be closely or peripherally associated to photosynthetic reaction centers that participate in harvesting and transferring radiant energy to the reaction center. Examples of this complex are found in bacterial species.


go_id: GO:0030079
term: light-harvesting complex, peripheral complex
ontology: CC
definition:
Bacteriochlorophyll a binding complex that is peripherally associated to the bacterial reaction center.


go_id: GO:0030080
term: B875 antenna complex
ontology: CC
definition:
Protein complex that surrounds and transfers excitation energy directly to the bacterial reaction center; binds bacteriochlorophyll a and has a single absorption band between 870 and 890 nm.


go_id: GO:0030081
term: B800-820 antenna complex
ontology: CC
definition:
Protein-pigment complex that absorbs light at 800 and 820 nm; is peripherally associated to the bacterial reaction center; transfers excitation energy to the B875 antenna complex.


go_id: GO:0030082
term: B800-850 antenna complex
ontology: CC
definition:
Protein-pigment complex that absorbs light at 800 and 850 nm; is peripherally associated to the bacterial reaction center; transfers excitation energy to the B875 antenna complex.


go_id: GO:0030083
term: PSI associated light-harvesting complex I, LHCIa subcomplex
ontology: CC
definition:
A pigment protein complex that forms part of the photosystem I associated light-harvesting complex I; contains two proteins (usually about 24 and 21.5 kDa); has a fluorescence maximum between 680 and 690 nm.


go_id: GO:0030084
term: PSI associated light-harvesting complex I, LHCIb subcomplex
ontology: CC
definition:
A pigment protein complex that forms part of the photosystem I associated light-harvesting complex I; contains two proteins (usually about 20 kDa); has a fluorescence maximum of 730 nm.


go_id: GO:0030085
term: PSII associated light-harvesting complex II, peripheral complex, LHCIIb subcomplex
ontology: CC
definition:
A pigment protein complex that forms part of the photosystem II associated light-harvesting complex II; contains two proteins (usually about 28 and 27 kDa), and may contain a third; peripherally located relative to other LHC polypeptides.


go_id: GO:0030089
term: phycobilisome
ontology: CC
definition:
Any of the granules, approximately 32 nm x 48 nm and consisting of highly aggregated phycobiliproteins, that are attached in arrays to the external face of a thylakoid membrane in algae of the phyla Cyanophyta and Rhodophyta, where they function as light-harvesting devices in photosynthesis. Excitation energy in the phycobilisome flows in the sequence: phycoerythrin, phycocyanin, allophycocyanin before passing to the antenna chlorophyll of photosystem II.


go_id: GO:0030091
term: protein repair
ontology: BP
definition:
The process of restoring a protein to its original state after damage by such things as oxidation or spontaneous decomposition of residues.


go_id: GO:0030093
term: chloroplast photosystem I
ontology: CC
definition:
Photosystem located in the chloroplast that functions as a light-dependent plastocyanin-ferredoxin oxidoreductase, transferring electrons from plastocyanin to ferredoxin. An example of this is found in Arabidopsis thaliana.


go_id: GO:0030094
term: plasma membrane-derived photosystem I
ontology: CC
definition:
A protein complex located in the plasma membrane-derived thylakoid. The photosystem functions as a light-dependent plastocyanin-ferredoxin oxidoreductase, transferring electrons from plastocyanin to ferredoxin. Examples of this complex are found in bacterial species.


go_id: GO:0030095
term: chloroplast photosystem II
ontology: CC
definition:
An integral chloroplast membrane complex containing the P680 reaction center. In the light, PSII functions as a water-plastoquinone oxidoreductase, transferring electrons from water to plastoquinone.


go_id: GO:0030096
term: plasma membrane-derived thylakoid photosystem II
ontology: CC
definition:
A protein complex, located in the membrane-derived thylakoid, containing the P680 reaction center. In the light, PSII functions as a water-plastoquinone oxidoreductase, transferring electrons from water to plastoquinone.


go_id: GO:0030097
term: hemopoiesis
ontology: BP
definition:
The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates.


go_id: GO:0030098
term: lymphocyte differentiation
ontology: BP
definition:
The process in which a relatively unspecialized precursor cell acquires specialized features of a lymphocyte. A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin.


go_id: GO:0030099
term: myeloid cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages.


go_id: GO:0030101
term: natural killer cell activation
ontology: BP
definition:
The change in morphology and behavior of a natural killer cell in response to a cytokine, chemokine, cellular ligand, or soluble factor.


go_id: GO:0030104
term: water homeostasis
ontology: BP
definition:
Any process involved in the maintenance of an internal steady state of water within an organism or cell.


go_id: GO:0030107
term: HLA-A specific inhibitory MHC class I receptor activity
ontology: MF
definition:
Combining with a MHC class I molecule of the HLA-A subclass to mediate signaling that inhibits activation of a lymphocyte.


go_id: GO:0030108
term: HLA-A specific activating MHC class I receptor activity
ontology: MF
definition:
Combining with a MHC class I molecule of the HLA-A subclass to mediate signaling that activates a lymphocyte.


go_id: GO:0030109
term: HLA-B specific inhibitory MHC class I receptor activity
ontology: MF
definition:
Combining with a MHC class I molecule of the HLA-B subclass to mediate signaling that inhibits activation of a lymphocyte.


go_id: GO:0030110
term: HLA-C specific inhibitory MHC class I receptor activity
ontology: MF
definition:
Combining with a MHC class I molecule of the HLA-C subclass to mediate signaling that inhibits activation of a lymphocyte.


go_id: GO:0030111
term: regulation of Wnt signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the activity of the Wnt signal transduction pathway.


go_id: GO:0030114
term: slime layer
ontology: CC
definition:
A slime layer is an easily removed, diffuse, unorganized layer of extracellular material that surrounds a cell. Specifically this consists mostly of exopolysaccharides, glycoproteins, and glycolipids.


go_id: GO:0030116
term: glial cell-derived neurotrophic factor receptor binding
ontology: MF
definition:
A growth factor that binds selectively and non-covalently to glial cell-derived neurotrophic factor receptors.


go_id: GO:0030117
term: membrane coat
ontology: CC
definition:
Any of several different proteinaceous coats that can associate with membranes. Membrane coats include those formed by clathrin plus an adaptor complex, the COPI and COPII complexes, and possibly others. They are found associated with membranes on many vesicles as well as other membrane features such as pits and perhaps tubules.


go_id: GO:0030118
term: clathrin coat
ontology: CC
definition:
A membrane coat found on coated pits and some coated vesicles; consists of polymerized clathrin triskelions, each comprising three clathrin heavy chains and three clathrin light chains, linked to the membrane via one of the AP adaptor complexes.


go_id: GO:0030119
term: AP-type membrane coat adaptor complex
ontology: CC
definition:
Any of several heterotetrameric complexes that link clathrin (or another coat-forming molecule, as hypothesized for AP-3 and AP-4) to a membrane surface; they are found on coated pits and coated vesicles, and mediate sorting of cargo proteins into vesicles. Each AP complex contains two large (a beta and one of either an alpha, gamma, delta, or epsilon) subunits (110-130 kDa), a medium (mu) subunit (approximately 50 kDa), and a small (sigma) subunit (15-20 kDa).


go_id: GO:0030121
term: AP-1 adaptor complex
ontology: CC
definition:
A heterotetrameric AP-type membrane coat adaptor complex that consists of beta1, gamma, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle; vesicles with AP-1-containing coats are normally found primarily in the trans-Golgi network. In at least humans, the AP-1 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (gamma1 and gamma2, mu1A and mu1B, and sigma1A, sigma1B and sigma1C).


go_id: GO:0030122
term: AP-2 adaptor complex
ontology: CC
definition:
A heterotetrameric AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits, and links clathrin to the membrane surface of a vesicle, and the cargo receptors during receptor/clathrin mediated endocytosis. Vesicles with AP-2-containing coats are normally found primarily near the plasma membrane, on endocytic vesicles. In at least humans, the AP-2 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different alpha genes (alphaA and alphaC).


go_id: GO:0030123
term: AP-3 adaptor complex
ontology: CC
definition:
A heterotetrameric AP-type membrane coat adaptor complex that consists of beta3, delta, mu3 and sigma3 subunits and is found associated with endosomal membranes. AP-3 does not appear to associate with clathrin in all organisms. In at least humans, the AP-3 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (beta3A and beta3B, mu3A and mu3B, and sigma3A and sigma3B).


go_id: GO:0030124
term: AP-4 adaptor complex
ontology: CC
definition:
An AP-type membrane coat adaptor complex that consists of beta4, epsilon, mu4 and sigma4 subunits and is found associated with membranes in the trans-Golgi network; it is not clear whether AP-4 forms clathrin coats in vivo.


go_id: GO:0030126
term: COPI vesicle coat
ontology: CC
definition:
One of two multimeric complexes that forms a membrane vesicle coat. The mammalian COPI subunits are called alpha-, beta-, beta'-, gamma-, delta-, epsilon- and zeta-COP. Vesicles with COPI coats are found associated with Golgi membranes at steady state.


go_id: GO:0030127
term: COPII vesicle coat
ontology: CC
definition:
One of two multimeric complexes that forms a membrane vesicle coat. COPII is best characterized in S. cerevisiae, where the subunits are called Sar1p, Sec13p, Sec31p, Sec23p, and Sec24p. Vesicles with COPII coats are found associated with endoplasmic reticulum (ER) membranes at steady state.


go_id: GO:0030132
term: clathrin coat of coated pit
ontology: CC
definition:
The coat found on coated pits and the coated vesicles derived from coated pits; comprises clathrin and the AP-2 adaptor complex.


go_id: GO:0030133
term: transport vesicle
ontology: CC
definition:
Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, from the Golgi to the ER (retrograde transport) or to destinations within or outside the cell.


go_id: GO:0030134
term: COPII-coated ER to Golgi transport vesicle
ontology: CC
definition:
A vesicle with a coat formed of the COPII coat complex proteins. The COPII coat complex is formed by the Sec23p/Sec24p and the Sec13p/Sec31p heterodimers. COPII-associated vesicles transport proteins from the rough endoplasmic reticulum to the Golgi apparatus (anterograde transport).


go_id: GO:0030135
term: coated vesicle
ontology: CC
definition:
Small membrane-bounded organelle formed by pinching off of a coated region of membrane. Some coats are made of clathrin, whereas others are made from other proteins.


go_id: GO:0030136
term: clathrin-coated vesicle
ontology: CC
definition:
A vesicle with a coat formed of clathrin connected to the membrane via one of the clathrin adaptor complexes.


go_id: GO:0030137
term: COPI-coated vesicle
ontology: CC
definition:
A vesicle with a coat formed of the COPI coat complex proteins. COPI-coated vesicles are found associated with Golgi membranes at steady state, are involved in Golgi to endoplasmic reticulum (retrograde) vesicle transport, and possibly also in intra-Golgi transport.


go_id: GO:0030139
term: endocytic vesicle
ontology: CC
definition:
A membrane-bounded intracellular vesicle formed by invagination of the plasma membrane around an extracellular substance. Endocytic vesicles fuse with early endosomes to deliver the cargo for further sorting.


go_id: GO:0030141
term: secretory granule
ontology: CC
definition:
A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules.


go_id: GO:0030143
term: COPI-coated inter-Golgi transport vesicle
ontology: CC
definition:
A vesicle that mediates transport of cargo within the Golgi complex (for example, between cisternae of the Golgi stack).


go_id: GO:0030144
term: alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3(6)-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl,1,6(3))-beta-D-mannosyl-1,4-N-acetyl-beta-D-glucosaminyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,2-(N-acetyl-beta-D-glucosaminyl-1,6)-1,2-alpha-D-mannosyl-1,3(6)-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6(3))-beta-D-mannosyl-1,4-N-acetyl-beta-D-glucosaminyl-R. Only branched mannose glycopeptides with non-reducing N-acetylglucosamine terminal residues act as acceptors.


go_id: GO:0030148
term: sphingolipid biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).


go_id: GO:0030149
term: sphingolipid catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).


go_id: GO:0030150
term: protein import into mitochondrial matrix
ontology: BP
definition:
The import of proteins across the outer and inner mitochondrial membranes into the matrix. Unfolded proteins enter the mitochondrial matrix with a chaperone protein; the information required to target the precursor protein from the cytosol to the mitochondrial matrix is contained within its N-terminal matrix-targeting sequence. Translocation of precursors to the matrix occurs at the rare sites where the outer and inner membranes are close together.


go_id: GO:0030152
term: bacteriocin biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a bacteriocin, any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary.


go_id: GO:0030153
term: bacteriocin immunity
ontology: BP
definition:
A process that mediates resistance to a bacteriocin: any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary.


go_id: GO:0030154
term: cell differentiation
ontology: BP
definition:
The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.


go_id: GO:0030155
term: regulation of cell adhesion
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix.


go_id: GO:0030157
term: pancreatic juice secretion
ontology: BP
definition:
The regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine. Pancreatic juice is slightly alkaline and contains numerous enzymes and inactive enzyme precursors including alpha-amylase, chymotrypsinogen, lipase, procarboxypeptidase, proelastase, prophospholipase A2, ribonuclease, and trypsinogen. Its high concentration of bicarbonate ions helps to neutralize the acid from the stomach.


go_id: GO:0030158
term: protein xylosyltransferase activity
ontology: MF
definition:
Catalysis of the transfer of a beta-D-xylosyl residue from UDP-D-xylose to the serine hydroxyl group of an acceptor protein substrate.


go_id: GO:0030159
term: signaling receptor complex adaptor activity
ontology: MF
definition:
The binding activity of a molecule that provides a physical support for the assembly of a multiprotein receptor signaling complex.


go_id: GO:0030160
term: synaptic receptor adaptor activity
ontology: MF
definition:
The binding activity of a molecule that provides a physical support bridging a synaptic signaling receptor and a downstream signaling molecule.


go_id: GO:0030162
term: regulation of proteolysis
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.


go_id: GO:0030163
term: protein catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.


go_id: GO:0030164
term: protein denaturation
ontology: BP
definition:
Structural change in proteins which destroys the native, active configuration without rupture of peptide bonds.


go_id: GO:0030166
term: proteoglycan biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.


go_id: GO:0030167
term: proteoglycan catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.


go_id: GO:0030168
term: platelet activation
ontology: BP
definition:
A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug.


go_id: GO:0030169
term: low-density lipoprotein particle binding
ontology: MF
definition:
Binding to a low-density lipoprotein particle, a lipoprotein particle that is rich in cholesterol esters and low in triglycerides, is typically composed of APOB100 and APOE, and has a density of 1.02-1.06 g/ml and a diameter of between 20-25 nm.


go_id: GO:0030170
term: pyridoxal phosphate binding
ontology: MF
definition:
Binding to pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.


go_id: GO:0030171
term: voltage-gated proton channel activity
ontology: MF
definition:
Enables the transmembrane transfer of a proton by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.


go_id: GO:0030173
term: integral component of Golgi membrane
ontology: CC
definition:
The component of the Golgi membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.


go_id: GO:0030174
term: regulation of DNA-templated DNA replication initiation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of initiation of DNA-dependent DNA replication; the process in which DNA becomes competent to replicate. In eukaryotes, replication competence is established in early G1 and lost during the ensuing S phase.


go_id: GO:0030175
term: filopodium
ontology: CC
definition:
Thin, stiff, actin-based protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal or dendritic growth cone, or a dendritic shaft.


go_id: GO:0030176
term: integral component of endoplasmic reticulum membrane
ontology: CC
definition:
The component of the endoplasmic reticulum membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.


go_id: GO:0030178
term: negative regulation of Wnt signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the Wnt signaling pathway.


go_id: GO:0030183
term: B cell differentiation
ontology: BP
definition:
The process in which a precursor cell type acquires the specialized features of a B cell. A B cell is a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity.


go_id: GO:0030185
term: nitric oxide transport
ontology: BP
definition:
The directed movement of nitric oxide, nitrogen monoxide, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0030187
term: melatonin biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of melatonin (N-acetyl-5-methoxytryptamine).


go_id: GO:0030198
term: extracellular matrix organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix.


go_id: GO:0030199
term: collagen fibril organization
ontology: BP
definition:
Any process that determines the size and arrangement of collagen fibrils within an extracellular matrix.


go_id: GO:0030200
term: heparan sulfate proteoglycan catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of proteoglycan containing heparan sulfate, any member of a group of glycosaminoglycans that have repeat units consisting of alternating alpha-(1->4) linked hexuronic acid and glucosamine residues, the former being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids, and the latter being either sulfated or acetylated on its amino group as well as sulfated on one of its hydroxyl groups.


go_id: GO:0030201
term: heparan sulfate proteoglycan metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving any proteoglycan containing heparan sulfate, any member of a group of glycosaminoglycans that have repeat units consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues, the former being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids, and the latter being either sulfated or acetylated on its amino group as well as sulfated on one of its hydroxyl groups.


go_id: GO:0030202
term: heparin metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells. They are similar to heparan sulfates but are of somewhat higher average Mr (6000-20000) and contain fewer N-acetyl groups and more N-sulfate and O-sulfate groups; they may be attached in the same manner to protein, forming proteoglycans. They consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.


go_id: GO:0030203
term: glycosaminoglycan metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving glycosaminoglycans, any of a group of polysaccharides that contain amino sugars.


go_id: GO:0030204
term: chondroitin sulfate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate. They usually occur linked to a protein to form proteoglycans. Two subgroups exist, one in which the sulfate is on the 4-position (chondroitin sulfate A) and the second in which it is in the 6-position (chondroitin sulfate C). They often are polydisperse and often differ in the degree of sulfation from tissue to tissue. The chains of repeating disaccharide are covalently linked to the side chains of serine residues in the polypeptide backbone of a protein by a glycosidic attachment through the trisaccharide unit galactosyl-galactosyl-xylosyl. Chondroitin sulfate B is more usually known as dermatan sulfate.


go_id: GO:0030205
term: dermatan sulfate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving dermatan sulfate, any of a group of glycosaminoglycans with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units. They are important components of ground substance or intercellular cement of skin and some connective tissues.


go_id: GO:0030206
term: chondroitin sulfate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.


go_id: GO:0030207
term: chondroitin sulfate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.


go_id: GO:0030208
term: dermatan sulfate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of dermatan sulfate, any glycosaminoglycan with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units.


go_id: GO:0030209
term: dermatan sulfate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of dermatan sulfate, any of a group of glycosaminoglycans with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units.


go_id: GO:0030210
term: heparin biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.


go_id: GO:0030211
term: heparin catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.


go_id: GO:0030212
term: hyaluronan metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine.


go_id: GO:0030213
term: hyaluronan biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine.


go_id: GO:0030214
term: hyaluronan catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine.


go_id: GO:0030216
term: keratinocyte differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a keratinocyte.


go_id: GO:0030217
term: T cell differentiation
ontology: BP
definition:
The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex.


go_id: GO:0030221
term: basophil differentiation
ontology: BP
definition:
The process in which a relatively unspecialized myeloid precursor cell acquires specialized features of a basophil cell.


go_id: GO:0030222
term: eosinophil differentiation
ontology: BP
definition:
The process in which a relatively unspecialized myeloid precursor cell acquires the specializes features of an eosinophil.


go_id: GO:0030224
term: monocyte differentiation
ontology: BP
definition:
The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a monocyte.


go_id: GO:0030225
term: macrophage differentiation
ontology: BP
definition:
The process in which a relatively unspecialized monocyte acquires the specialized features of a macrophage.


go_id: GO:0030228
term: lipoprotein particle receptor activity
ontology: MF
definition:
Combining with a lipoprotein particle and delivering the lipoprotein particle into the cell via endocytosis. A lipoprotein particle, also known as a lipoprotein, is a clathrate complex consisting of a lipid enwrapped in a protein host without covalent binding in such a way that the complex has a hydrophilic outer surface consisting of all the protein and the polar ends of any phospholipids.


go_id: GO:0030229
term: very-low-density lipoprotein particle receptor activity
ontology: MF
definition:
Combining with a very-low-density lipoprotein particle and delivering the very-low-density lipoprotein into the cell via endocytosis.


go_id: GO:0030232
term: insulin control element activator complex
ontology: CC
definition:
Transcription factor complex that binds to the insulin control element (ICE), a DNA sequence element found within the 5'-flanking region of the insulin gene, and activates ICE-mediated transcription.


go_id: GO:0030233
term: deoxynucleotide transmembrane transporter activity
ontology: MF
definition:
Catalyzes transport of all four deoxy (d) NDPs, and, less efficiently, the corresponding dNTPs, in exchange for dNDPs, ADP, or ATP.


go_id: GO:0030240
term: skeletal muscle thin filament assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in skeletal muscle.


go_id: GO:0030241
term: skeletal muscle myosin thick filament assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of proteins to form the myosin-based thick filaments of myofibrils in skeletal muscle.


go_id: GO:0030242
term: autophagy of peroxisome
ontology: BP
definition:
The process in which peroxisomes are delivered to a type of vacuole and degraded in response to changing nutrient conditions.


go_id: GO:0030243
term: cellulose metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation.


go_id: GO:0030244
term: cellulose biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation.


go_id: GO:0030245
term: cellulose catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation.


go_id: GO:0030246
term: carbohydrate binding
ontology: MF
definition:
Binding to a carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates.


go_id: GO:0030247
term: polysaccharide binding
ontology: MF
definition:
Binding to a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.


go_id: GO:0030253
term: protein secretion by the type I secretion system
ontology: BP
definition:
The process in which proteins are secreted into the extracellular milieu via the type I secretion system; secretion occurs in a continuous process without the distinct presence of periplasmic intermediates and does not involve proteolytic processing of secreted proteins.


go_id: GO:0030254
term: protein secretion by the type III secretion system
ontology: BP
definition:
The process in which proteins are transferred into the extracellular milieu or directly into host cells by the bacterial type III secretion system; secretion occurs in a continuous process without the distinct presence of periplasmic intermediates and does not involve proteolytic processing of secreted proteins.


go_id: GO:0030255
term: protein secretion by the type IV secretion system
ontology: BP
definition:
The process in which proteins are transferred into the extracellular milieu or directly into host cells, via the type IV protein secretion system.


go_id: GO:0030256
term: type I protein secretion system complex
ontology: CC
definition:
A complex of three secretory proteins that carry out secretion in the type I secretion system: an inner membrane transport ATPase (termed ABC protein for ATP-binding cassette), which provides the energy for protein secretion; an outer membrane protein, which is exported via the sec pathway; and a membrane fusion protein, which is anchored in the inner membrane and spans the periplasmic space.


go_id: GO:0030257
term: type III protein secretion system complex
ontology: CC
definition:
A complex of approximately 20 proteins, most of which are located in the cytoplasmic membrane that carries out protein secretion in the bacterial type III secretion system; type III secretion also requires a cytoplasmic, probably membrane-associated ATPase.


go_id: GO:0030258
term: lipid modification
ontology: BP
definition:
The covalent alteration of one or more fatty acids in a lipid, resulting in a change in the properties of the lipid.


go_id: GO:0030261
term: chromosome condensation
ontology: BP
definition:
The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells.


go_id: GO:0030262
term: apoptotic nuclear changes
ontology: BP
definition:
Alterations undergone by nuclei at the molecular and morphological level as part of the execution phase of apoptosis.


go_id: GO:0030264
term: nuclear fragmentation involved in apoptotic nuclear change
ontology: BP
definition:
The breakdown of the nucleus into small membrane-bounded compartments, or blebs, each of which contain compacted DNA.


go_id: GO:0030265
term: phospholipase C-activating rhodopsin mediated signaling pathway
ontology: BP
definition:
A phospholipase C-activating receptor G protein-coupled receptor signaling pathway initiated by a rhodopsin molecule being activated by a photon, and ending with the regulation of a downstream cellular process, e.g. transcription.


go_id: GO:0030268
term: methylenetetrahydromethanopterin dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 5,10-methylenetetrahydromethanopterin + coenzyme F420 + 2 H(+) = 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + reduced coenzyme F420.


go_id: GO:0030269
term: tetrahydromethanopterin S-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: 5-methyltetrahydromethanopterin + coenzyme M = 5,6,7,8-tetrahydromethanopterin + methyl-coenzyme M. 2-(methylthio)ethanesulfonate is also known as methyl-CoM.


go_id: GO:0030270
term: formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: 5,6,7,8-tetrahydromethanopterin + N-formylmethanofuran + H(+) = N(5)-formyl-5,6,7,8-tetrahydromethanopterin + methanofuran.


go_id: GO:0030272
term: 5-formyltetrahydrofolate cyclo-ligase activity
ontology: MF
definition:
Catalysis of the reaction: 5-formyltetrahydrofolate + ATP = 5,10-methenyltetrahydrofolate + ADP + H(+) + phosphate.


go_id: GO:0030273
term: melanin-concentrating hormone receptor activity
ontology: MF
definition:
Combining with the cyclic peptide hormone melanin-concentrating hormone to initiate a change in cell activity.


go_id: GO:0030274
term: LIM domain binding
ontology: MF
definition:
Binding to a LIM domain (for Lin-11 Isl-1 Mec-3) of a protein, a domain with seven conserved cysteine residues and a histidine, that binds two zinc ions and acts as an interface for protein-protein interactions.


go_id: GO:0030276
term: clathrin binding
ontology: MF
definition:
Binding to a clathrin heavy or light chain, the main components of the coat of coated vesicles and coated pits, and which also occurs in synaptic vesicles.


go_id: GO:0030277
term: maintenance of gastrointestinal epithelium
ontology: BP
definition:
Protection of epithelial surfaces of the gastrointestinal tract from proteolytic and caustic digestive agents.


go_id: GO:0030278
term: regulation of ossification
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance.


go_id: GO:0030279
term: negative regulation of ossification
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance.


go_id: GO:0030280
term: structural constituent of skin epidermis
ontology: MF
definition:
The action of a molecule that contributes to the structural integrity of an epidermal cutaneous structure.


go_id: GO:0030281
term: structural constituent of cutaneous appendage
ontology: MF
definition:
The action of a molecule that contributes to the structural integrity of cutaneous epidermal structures such as hairs, scales, or feathers.


go_id: GO:0030282
term: bone mineralization
ontology: BP
definition:
The deposition of hydroxyapatite, a form of calcium phosphate with the formula Ca10(PO4)6(OH)2, in bone tissue.


go_id: GO:0030284
term: nuclear estrogen receptor activity
ontology: MF
definition:
Combining with estrogen and transmitting the signal within the cell to trigger a change in cell activity or function.


go_id: GO:0030285
term: integral component of synaptic vesicle membrane
ontology: CC
definition:
The component of the synaptic vesicle membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.


go_id: GO:0030286
term: dynein complex
ontology: CC
definition:
Any of several large complexes that contain two or three dynein heavy chains and several light chains, and have microtubule motor activity.


go_id: GO:0030287
term: cell wall-bounded periplasmic space
ontology: CC
definition:
The region between the plasma membrane and the cell wall in organisms lacking an outer cell membrane such as yeast and Gram positive bacteria. The region is thinner than the equivalent in Gram negative bacteria.


go_id: GO:0030288
term: outer membrane-bounded periplasmic space
ontology: CC
definition:
The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin peptidoglycan layer (PGL), also referred to as a thin cell wall.


go_id: GO:0030289
term: protein phosphatase 4 complex
ontology: CC
definition:
A protein serine/threonine phosphatase complex formed by the catalytic subunit of protein phosphatase 4 plus one or more regulatory subunits.


go_id: GO:0030290
term: sphingolipid activator protein activity
ontology: MF
definition:
Any of a group of peptide cofactors of enzymes for the lysosomal degradation of sphingolipids. They stimulate various enzymes, including glucosylceramidase, galactosylceramidase, cerebroside-sulfatase, alpha-galactosidase, beta-galactosidase, and sphingomyelin phosphodiesterase.


go_id: GO:0030293
term: transmembrane receptor protein tyrosine kinase inhibitor activity
ontology: MF
definition:
Binds to and stops, prevents or reduces the activity of a transmembrane receptor protein tyrosine kinase.


go_id: GO:0030296
term: protein tyrosine kinase activator activity
ontology: MF
definition:
Increases the activity of a protein tyrosine kinase, an enzyme which phosphorylates a tyrosyl phenolic group on a protein.


go_id: GO:0030300
term: regulation of intestinal cholesterol absorption
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of absorption of cholesterol into the blood, and the exclusion of other sterols from absorption.


go_id: GO:0030301
term: cholesterol transport
ontology: BP
definition:
The directed movement of cholesterol, cholest-5-en-3-beta-ol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0030302
term: deoxynucleotide transport
ontology: BP
definition:
The directed movement of a deoxynucleotide, a deoxyribonucleoside in ester linkage to phosphate, commonly at the 5' position of deoxyribose, into, out of or within a cell.


go_id: GO:0030305
term: heparanase activity
ontology: MF
definition:
Catalysis of the cleavage of heparan sulfate; can degrade both heparan sulfate and heparin glycosaminoglycan chains.


go_id: GO:0030308
term: negative regulation of cell growth
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.


go_id: GO:0030309
term: poly-N-acetyllactosamine metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving poly-N-acetyllactosamine, a carbohydrate composed of N-acetyllactosamine repeats (Gal-beta-1,4-GlcNAc-beta-1,3)n.


go_id: GO:0030310
term: poly-N-acetyllactosamine catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of poly-N-acetyllactosamine, a carbohydrate composed of N-acetyllactosamine repeats (Gal-beta-1,4-GlcNAc-beta-1,3)n.


go_id: GO:0030311
term: poly-N-acetyllactosamine biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of poly-N-acetyllactosamine, a carbohydrate composed of N-acetyllactosamine repeats (Gal-beta-1,4-GlcNAc-beta-1,3)n.


go_id: GO:0030312
term: external encapsulating structure
ontology: CC
definition:
A structure that lies outside the plasma membrane and surrounds the entire cell or cells. This does not include the periplasmic space.


go_id: GO:0030313
term: cell envelope
ontology: CC
definition:
An envelope that surrounds a bacterial cell and includes the cytoplasmic membrane and everything external, encompassing the periplasmic space, cell wall, and outer membrane if present.


go_id: GO:0030314
term: junctional membrane complex
ontology: CC
definition:
Complex formed in muscle cells between the membrane of the sarcoplasmic reticulum and invaginations of the plasma membrane (T-tubules).


go_id: GO:0030315
term: T-tubule
ontology: CC
definition:
Invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril. The ends of T-tubules make contact with the sarcoplasmic reticulum membrane.


go_id: GO:0030316
term: osteoclast differentiation
ontology: BP
definition:
The process in which a relatively unspecialized monocyte acquires the specialized features of an osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue.


go_id: GO:0030317
term: flagellated sperm motility
ontology: BP
definition:
The directed, self-propelled movement of a cilium (aka flagellum) that contributes to the movement of a flagellated sperm.


go_id: GO:0030320
term: cellular monovalent inorganic anion homeostasis
ontology: BP
definition:
Any process involved in the maintenance of an internal steady state of monovalent inorganic anions at the level of a cell.


go_id: GO:0030322
term: stabilization of membrane potential
ontology: BP
definition:
The accomplishment of a non-fluctuating membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.


go_id: GO:0030323
term: respiratory tube development
ontology: BP
definition:
The process whose specific outcome is the progression of the respiratory tube over time, from its formation to the mature structure. The respiratory tube is assumed to mean any tube in the respiratory tract.


go_id: GO:0030324
term: lung development
ontology: BP
definition:
The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax.


go_id: GO:0030325
term: adrenal gland development
ontology: BP
definition:
The process whose specific outcome is the progression of the adrenal gland over time, from its formation to the mature structure. This gland can either be a discrete structure located bilaterally above each kidney, or a cluster of cells in the head kidney that perform the functions of the adrenal gland. In either case, this organ consists of two cells types, aminergic chromaffin cells and steroidogenic cortical cells.


go_id: GO:0030326
term: embryonic limb morphogenesis
ontology: BP
definition:
The process, occurring in the embryo, by which the anatomical structures of the limb are generated and organized. A limb is an appendage of an animal used for locomotion or grasping.


go_id: GO:0030328
term: prenylcysteine catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of prenylcysteine, 3-methyl-2-buten-1-yl-cysteine, a derivative of the amino acid cysteine formed by the covalent addition of a prenyl residue.


go_id: GO:0030329
term: prenylcysteine metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving prenylcysteine, 3-methyl-2-buten-1-yl-cysteine, a derivative of the amino acid cysteine formed by the covalent addition of a prenyl residue.


go_id: GO:0030330
term: DNA damage response, signal transduction by p53 class mediator
ontology: BP
definition:
A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.


go_id: GO:0030332
term: cyclin binding
ontology: MF
definition:
Binding to cyclins, proteins whose levels in a cell varies markedly during the cell cycle, rising steadily until mitosis, then falling abruptly to zero. As cyclins reach a threshold level, they are thought to drive cells into G2 phase and thus to mitosis.


go_id: GO:0030337
term: DNA polymerase processivity factor activity
ontology: MF
definition:
An enzyme regulator activity that increases the processivity of polymerization by DNA polymerase, by allowing the polymerase to move rapidly along DNA while remaining topologically bound to it.


go_id: GO:0030338
term: CMP-N-acetylneuraminate monooxygenase activity
ontology: MF
definition:
Catalysis of the reaction: CMP-N-acetylneuraminate + NADPH + H+ + O2 = CMP-N-glycoloylneuraminate + NADP+ + H2O.


go_id: GO:0030339
term: fatty-acyl-ethyl-ester synthase activity
ontology: MF
definition:
Catalysis of the reaction: a long-chain-acyl ethyl ester + H2O = a long-chain carboxylic acid + ethanol.


go_id: GO:0030340
term: hyaluronate lyase activity
ontology: MF
definition:
Catalysis of the reaction: hyaluronate = n 3-(4-deoxy-beta-D-gluc-4-enuronosyl)-N-acetyl-D-glucosamine.


go_id: GO:0030341
term: chondroitin AC lyase activity
ontology: MF
definition:
Catalysis of the eliminative degradation of polysaccharides containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucuronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups.


go_id: GO:0030342
term: 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity
ontology: MF
definition:
Catalysis of the hydroxylation of C-24 of 1-alpha,25-hydroxycholecalciferol (25-hydroxyvitamin D3; calcitriol).


go_id: GO:0030350
term: iron-responsive element binding
ontology: MF
definition:
Binding to an iron-responsive element, a regulatory sequence found in the 5'- and 3'-untranslated regions of mRNAs encoding many iron-binding proteins.


go_id: GO:0030351
term: inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity
ontology: MF
definition:
Catalysis of the reaction: inositol-1,3,4,5,6-pentakisphosphate + H2O = inositol-1,4,5,6-tetrakisphosphate + phosphate.


go_id: GO:0030352
term: inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity
ontology: MF
definition:
Catalysis of the reaction: inositol-1,4,5,6-tetrakisphosphate + H2O = inositol-1,4,5-trisphosphate + phosphate.


go_id: GO:0030353
term: fibroblast growth factor receptor antagonist activity
ontology: MF
definition:
Interacts with the fibroblast growth factor receptor to reduce the action of another ligand, the agonist.


go_id: GO:0030354
term: melanin-concentrating hormone activity
ontology: MF
definition:
The action characteristic of melanin-concentrating hormone, a cyclic peptide hormone that, upon receptor binding, induces melanin aggregation in melanocytes, and is also involved in regulating food intake and energy balance in mammals.


go_id: GO:0030366
term: molybdopterin synthase activity
ontology: MF
definition:
Catalysis of the conversion of precursor Z to molybdopterin, the final step in molybdopterin biosynthesis.


go_id: GO:0030368
term: interleukin-17 receptor activity
ontology: MF
definition:
Combining with any member of the interleukin-17 family of cytokines and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


go_id: GO:0030369
term: ICAM-3 receptor activity
ontology: MF
definition:
Combining with ICAM-3, intercellular adhesion molecule 3, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. ICAM-3, or CD50, are constitutively expressed on monocytes, granulocytes and lymphocytes; on physiological stimulation, they become transiently phosphorylated on serine residues.


go_id: GO:0030373
term: high molecular weight B cell growth factor receptor activity
ontology: MF
definition:
Combining with a high molecular weight B cell growth factor and transmitting the signal to initiate a change in cell activity.


go_id: GO:0030374
term: nuclear receptor coactivator activity
ontology: MF
definition:
A transcription coactivator activity that activates or increases the transcription of specific gene sets via binding to a DNA-bound nuclear receptor, either on its own or as part of a complex. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators. A fourth class of coactivator activity is the bridging of a DNA-binding transcription factor to the general (basal) transcription machinery. The Mediator complex, which bridges sequence-specific DNA binding transcription factors and RNA polymerase, is also a transcription coactivator.


go_id: GO:0030379
term: neurotensin receptor activity, non-G protein-coupled
ontology: MF
definition:
Combining with neurotensin, a neuropeptide active in the central and peripheral nervous system in mammals, and transmitting the signal from one side of the membrane to the other by a mechanism independent of coupling to G proteins.


go_id: GO:0030381
term: chorion-containing eggshell pattern formation
ontology: BP
definition:
The regionalization process that gives rise to the structural pattern of a chorion-containing eggshell such as those found in insects.


go_id: GO:0030382
term: sperm mitochondrion organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of sperm mitochondria; the process in which they take on their characteristic morphology; they are flattened, elongated, and arranged circumferentially into a tight helical coil around the tail-dense fibers of the mature sperm.


go_id: GO:0030388
term: fructose 1,6-bisphosphate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis.


go_id: GO:0030389
term: fructosamine metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving fructosamine, a fructose molecule containing an amino group in place of a hydroxyl group.


go_id: GO:0030391
term: fructosamine biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of fructosamine, a fructose molecule containing an amino group in place of a hydroxyl group.


go_id: GO:0030392
term: fructosamine catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of fructosamine, a fructose molecule containing an amino group in place of a hydroxyl group.


go_id: GO:0030393
term: fructoselysine metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving fructoselysine, a fructose molecule containing a lysine group in place of a hydroxyl group.


go_id: GO:0030394
term: fructoseglycine metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving fructoseglycine, a fructose molecule containing a glycine group in place of a hydroxyl group.


go_id: GO:0030398
term: peroxisomal membrane disassembly
ontology: BP
definition:
The controlled breakdown of the membranes of cargo-carrying vesicles formed during peroxisome degradation.


go_id: GO:0030408
term: glycine formimidoyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: 5-formimidoyltetrahydrofolate + glycine = (6S)-5,6,7,8-tetrahydrofolate + N-formimidoylglycine.


go_id: GO:0030409
term: glutamate formimidoyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: 5-formimidoyltetrahydrofolate + L-glutamate = tetrahydrofolate + N-formimidoyl-L-glutamate.


go_id: GO:0030410
term: nicotianamine synthase activity
ontology: MF
definition:
Catalysis of the reaction: 3 S-adenosyl-L-methionine(1+) = 3 S-methyl-5'-thioadenosine + 3 H(+) + nicotianamine.


go_id: GO:0030412
term: formimidoyltetrahydrofolate cyclodeaminase activity
ontology: MF
definition:
Catalysis of the reaction: 5-formimidoyltetrahydrofolate + 2 H(+) = 5,10-methenyltetrahydrofolate + NH(4)(+).


go_id: GO:0030413
term: competence pheromone activity
ontology: MF
definition:
A small peptide excreted by a naturally transformable bacterium (e.g. Bacillus subtilis) that transmits a signal required for the establishment of competence.


go_id: GO:0030414
term: peptidase inhibitor activity
ontology: MF
definition:
Binds to and stops, prevents or reduces the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds.


go_id: GO:0030417
term: nicotianamine metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving nicotianamine, 2(S),3'2(S),3''(S)-N-(N-(3-amino-3-carboxypropyl)-3-amino-3-carboxypropyl)-azetidine-2-carboxylic acid.


go_id: GO:0030418
term: nicotianamine biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of nicotianamine, 2(S),3'2(S),3''(S)-N-(N-(3-amino-3-carboxypropyl)-3-amino-3-carboxypropyl)-azetidine-2-carboxylic acid.


go_id: GO:0030419
term: nicotianamine catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of nicotianamine, 2(S),3'2(S),3''(S)-N-(N-(3-amino-3-carboxypropyl)-3-amino-3-carboxypropyl)-azetidine-2-carboxylic acid.


go_id: GO:0030420
term: establishment of competence for transformation
ontology: BP
definition:
The process in which a naturally transformable bacterium acquires the ability to take up exogenous DNA. This term should be applied only to naturally transformable bacteria, and should not be used in the context of artificially induced bacterial transformation.


go_id: GO:0030422
term: siRNA processing
ontology: BP
definition:
A process leading to the generation of a functional small interfering RNA (siRNA). Includes the cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides. May also include amplification of the siRNA by RNA-directed RNA polymerase.


go_id: GO:0030424
term: axon
ontology: CC
definition:
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.


go_id: GO:0030425
term: dendrite
ontology: CC
definition:
A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.


go_id: GO:0030426
term: growth cone
ontology: CC
definition:
The migrating motile tip of a growing neuron projection, where actin accumulates, and the actin cytoskeleton is the most dynamic.


go_id: GO:0030428
term: cell septum
ontology: CC
definition:
A structure composed of peptidoglycan and often chitin in addition to other materials. It usually forms perpendicular to the long axis of a cell or hypha and grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells.


go_id: GO:0030431
term: sleep
ontology: BP
definition:
Any process in which an organism enters and maintains a periodic, readily reversible state of reduced awareness and metabolic activity. Usually accompanied by physical relaxation, the onset of sleep in humans and other mammals is marked by a change in the electrical activity of the brain.


go_id: GO:0030432
term: peristalsis
ontology: BP
definition:
A wavelike sequence of involuntary muscular contraction and relaxation that passes along a tubelike structure, such as the intestine, impelling the contents onwards.


go_id: GO:0030433
term: ubiquitin-dependent ERAD pathway
ontology: BP
definition:
The series of steps necessary to target endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. Begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the ER to the cytosol, protein ubiquitination necessary for correct substrate transfer, transport of the protein to the proteasome, and ends with degradation of the protein by the cytoplasmic proteasome.


go_id: GO:0030435
term: sporulation resulting in formation of a cellular spore
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires the specialized features of a cellular spore, a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction.


go_id: GO:0030436
term: asexual sporulation
ontology: BP
definition:
The formation of spores derived from the products of an asexual cell division. Examples of this process are found in bacteria and fungi.


go_id: GO:0030437
term: ascospore formation
ontology: BP
definition:
The process in which cells that are products of meiosis acquire the specialized features of ascospores. Ascospores are generally found in clusters of four or eight spores within a single mother cell, the ascus, and are characteristic of the ascomycete fungi (phylum Ascomycota).


go_id: GO:0030445
term: yeast-form cell wall
ontology: CC
definition:
The wall surrounding a cell of a dimorphic fungus growing in the single-cell budding yeast form, in contrast to the filamentous or hyphal form.


go_id: GO:0030447
term: filamentous growth
ontology: BP
definition:
The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.


go_id: GO:0030448
term: hyphal growth
ontology: BP
definition:
Growth of fungi as threadlike, tubular structures that may contain multiple nuclei and may or may not be divided internally by septa, or cross-walls.


go_id: GO:0030450
term: regulation of complement activation, classical pathway
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the classical pathway of complement activation.


go_id: GO:0030451
term: regulation of complement activation, alternative pathway
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the alternative pathway of complement activation.


go_id: GO:0030473
term: nuclear migration along microtubule
ontology: BP
definition:
The directed movement of the nucleus along microtubules within the cell, mediated by motor proteins.


go_id: GO:0030476
term: ascospore wall assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form an ascospore wall. During sporulation in Ascomycota, each ascospore nucleus becomes surrounded by a specialized spore wall, formed by deposition of spore wall components in the lumenal space between the outer and inner leaflets of the prospore membrane. An example of this process is found in Saccharomyces cerevisiae.


go_id: GO:0030478
term: actin cap
ontology: CC
definition:
Polarized accumulation of cytoskeletal proteins (including F-actin) and regulatory proteins in a cell. An example of this is the actin cap found in Saccharomyces cerevisiae.


go_id: GO:0030479
term: actin cortical patch
ontology: CC
definition:
An endocytic patch  that consists of an actin-containing structure found at the plasma membrane in cells; formed of networks of branched actin filaments that lie just beneath the plasma membrane and assemble, move, and disassemble rapidly. An example of this is the actin cortical patch found in Saccharomyces cerevisiae.


go_id: GO:0030487
term: inositol-4,5-bisphosphate 5-phosphatase activity
ontology: MF
definition:
Catalysis of the reaction: 1D-myo-inositol 4,5-bisphosphate + H2O = 1D-myo-inositol 4-phosphate + phosphate.


go_id: GO:0030490
term: maturation of SSU-rRNA
ontology: BP
definition:
Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule.


go_id: GO:0030491
term: heteroduplex formation
ontology: BP
definition:
The formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules.


go_id: GO:0030492
term: hemoglobin binding
ontology: MF
definition:
Binding to hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin.


go_id: GO:0030493
term: bacteriochlorophyll metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving a bacteriochlorophyll, any of the chlorophylls of photosynthetic bacteria. They differ structurally from the chlorophylls of higher plants.


go_id: GO:0030494
term: bacteriochlorophyll biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a bacteriochlorophyll, any of the chlorophylls of photosynthetic bacteria. They differ structurally from the chlorophylls of higher plants.


go_id: GO:0030495
term: bacteriochlorophyll catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of bacteriochlorophyll, any of the chlorophylls of photosynthetic bacteria. They differ structurally from the chlorophylls of higher plants.


go_id: GO:0030496
term: midbody
ontology: CC
definition:
A thin cytoplasmic bridge formed between daughter cells at the end of cytokinesis. The midbody forms where the contractile ring constricts, and may persist for some time before finally breaking to complete cytokinesis.


go_id: GO:0030505
term: inorganic diphosphate transport
ontology: BP
definition:
The directed movement of inorganic diphosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0030506
term: ankyrin binding
ontology: MF
definition:
Binding to ankyrin, a 200 kDa cytoskeletal protein that attaches other cytoskeletal proteins to integral membrane proteins.


go_id: GO:0030507
term: spectrin binding
ontology: MF
definition:
Binding to spectrin, a protein that is the major constituent of the erythrocyte cytoskeletal network. It associates with band 4.1 (see band protein) and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. It is composed of nonhomologous chains, alpha and beta, which aggregate side-to-side in an antiparallel fashion to form dimers, tetramers, and higher polymers.


go_id: GO:0030509
term: BMP signaling pathway
ontology: BP
definition:
The series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


go_id: GO:0030510
term: regulation of BMP signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the activity of any BMP receptor signaling pathway.


go_id: GO:0030511
term: positive regulation of transforming growth factor beta receptor signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of TGF-beta receptor signaling pathway activity.


go_id: GO:0030512
term: negative regulation of transforming growth factor beta receptor signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway.


go_id: GO:0030513
term: positive regulation of BMP signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of BMP signaling pathway activity.


go_id: GO:0030514
term: negative regulation of BMP signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway.


go_id: GO:0030518
term: intracellular steroid hormone receptor signaling pathway
ontology: BP
definition:
The series of molecular signals initiated by a steroid binding to an intracellular steroid hormone receptor.


go_id: GO:0030520
term: intracellular estrogen receptor signaling pathway
ontology: BP
definition:
The series of molecular signals initiated by estrogen binding to an intracellular receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.


go_id: GO:0030521
term: androgen receptor signaling pathway
ontology: BP
definition:
The series of molecular signals initiated by androgen binding to its receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.


go_id: GO:0030532
term: small nuclear ribonucleoprotein complex
ontology: CC
definition:
A ribonucleoprotein complex that contains at least one RNA of the small nuclear RNA (snRNA) class and as well as its associated proteins. These are typically named after the snRNA(s) they contain, e.g. U1 snRNP, U4/U6 snRNP, or 7SK snRNP. Many, of these complexes become part of the spliceosome involved in splicing of nuclear mRNAs. Others are involved in regulation of transcription elongation or 3'-end processing of replication-dependent histone pre-mRNAs.


go_id: GO:0030533
term: triplet codon-amino acid adaptor activity
ontology: MF
definition:
The codon binding activity of a tRNA that positions an activated amino acid, mediating its insertion at the correct point in the sequence of a nascent polypeptide chain during protein synthesis.


go_id: GO:0030537
term: larval behavior
ontology: BP
definition:
Behavior in a larval form of an organism, an immature organism that must undergo metamorphosis to assume adult characteristics.


go_id: GO:0030538
term: embryonic genitalia morphogenesis
ontology: BP
definition:
The process, occurring in the embryo, by which the anatomical structures of the genitalia are generated and organized.


go_id: GO:0030539
term: male genitalia development
ontology: BP
definition:
The process whose specific outcome is the progression of the male genitalia over time, from its formation to the mature structure.


go_id: GO:0030540
term: female genitalia development
ontology: BP
definition:
The process whose specific outcome is the progression of the female genitalia over time, from formation to the mature structure.


go_id: GO:0030543
term: 2-micrometer plasmid partitioning
ontology: BP
definition:
The process in which copies of the 2-micrometer plasmid, found in fungi such as Saccharomyces, are distributed to daughter cells upon cell division.


go_id: GO:0030546
term: signaling receptor activator activity
ontology: MF
definition:
The function of interacting (directly or indirectly) with receptors such that the proportion of receptors in the active form is increased.


go_id: GO:0030548
term: acetylcholine receptor regulator activity
ontology: MF
definition:
Interacting (directly or indirectly) with acetylcholine receptors such that the proportion of receptors in the active form is changed.


go_id: GO:0030549
term: acetylcholine receptor activator activity
ontology: MF
definition:
Interacting (directly or indirectly) with acetylcholine receptors such that the proportion of receptors in the active form is increased.


go_id: GO:0030551
term: cyclic nucleotide binding
ontology: MF
definition:
Binding to a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue.


go_id: GO:0030555
term: RNA modification guide activity
ontology: MF
definition:
Specifies the site of a posttranscriptional modification in an RNA molecule by base pairing with a short sequence around the target residue.


go_id: GO:0030556
term: rRNA modification guide activity
ontology: MF
definition:
Specifies the site of a posttranscriptional modification in an rRNA molecule by base pairing with a short sequence around the target residue.


go_id: GO:0030557
term: tRNA modification guide activity
ontology: MF
definition:
Specifies the site of a posttranscriptional modification in a tRNA molecule by base pairing with a short sequence around the target residue.


go_id: GO:0030558
term: RNA pseudouridylation guide activity
ontology: MF
definition:
Specifies the site of pseudouridylation in an RNA molecule by base pairing with a short sequence around the target residue.


go_id: GO:0030559
term: rRNA pseudouridylation guide activity
ontology: MF
definition:
Specifies the site of pseudouridylation in an rRNA molecule by base pairing with a short sequence around the target residue.


go_id: GO:0030560
term: tRNA pseudouridylation guide activity
ontology: MF
definition:
Specifies the site of pseudouridylation in a tRNA molecule by base pairing with a short sequence around the target residue.


go_id: GO:0030561
term: RNA 2'-O-ribose methylation guide activity
ontology: MF
definition:
Specifies the site of 2'-O-ribose methylation in an RNA molecule by base pairing with a short sequence around the target residue.


go_id: GO:0030562
term: rRNA 2'-O-ribose methylation guide activity
ontology: MF
definition:
Specifies the site of 2'-O-ribose methylation in an rRNA molecule by base pairing with a short sequence around the target residue.


go_id: GO:0030563
term: snRNA 2'-O-ribose methylation guide activity
ontology: MF
definition:
Activity that provides specificity to a methylase by using base complementarity to guide site-specific 2'-O-ribose methylations to a small nuclear RNA molecule.


go_id: GO:0030564
term: tRNA 2'-O-ribose methylation guide activity
ontology: MF
definition:
Specifies the site of 2'-O-ribose methylation in a tRNA molecule by base pairing with a short sequence around the target residue.


go_id: GO:0030565
term: snRNA pseudouridylation guide activity
ontology: MF
definition:
Activity that provides specificity to a pseudouridine synthetase by using base complementarity to guide site-specific pseudouridylations to a small nuclear RNA molecule.


go_id: GO:0030566
term: snRNA modification guide activity
ontology: MF
definition:
Specifies the site of a posttranscriptional modification in an snRNA molecule by base pairing with a short sequence around the target residue.


go_id: GO:0030570
term: pectate lyase activity
ontology: MF
definition:
Catalysis of the reaction: a pectate = a pectate + a pectate oligosaccharide with 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate end. This reaction is the eliminative cleavage of pectate to give oligosaccharides with 4-deoxy-alpha-D-gluc-4-enuronosyl groups at their non-reducing ends.


go_id: GO:0030572
term: phosphatidyltransferase activity
ontology: MF
definition:
Catalysis of the reaction involving the transfer of a phosphatidate (otherwise known as diacylglycerol 3-phosphosphate) group.


go_id: GO:0030573
term: bile acid catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of bile acids, any of a group of steroid carboxylic acids occurring in bile.


go_id: GO:0030574
term: collagen catabolic process
ontology: BP
definition:
The proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix, usually carried out by proteases secreted by nearby cells.


go_id: GO:0030575
term: nuclear body organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of any of the extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.


go_id: GO:0030576
term: Cajal body organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of Cajal bodies, nuclear bodies that appear ultrastructurally as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter and are enriched in ribonucleoproteins, and certain general RNA polymerase II transcription factors.


go_id: GO:0030577
term: Lands organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of Lands, a class of nuclear body that react against SP140 auto-antibodies.


go_id: GO:0030578
term: PML body organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of PML bodies, a class of nuclear body; they react against SP100 auto-antibodies (PML = promyelocytic leukemia).


go_id: GO:0030579
term: ubiquitin-dependent SMAD protein catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of SMAD signaling proteins by ubiquitination and targeting to the proteasome.


go_id: GO:0030580
term: quinone cofactor methyltransferase activity
ontology: MF
definition:
Catalysis of the transfer of a methyl group from S-adenosylmethionine during the synthesis of quinone cofactors such as ubiquinone (coenzyme Q), menaquinone (vitamin K2), plastoquinone and phylloquinone (vitamin K1).


go_id: GO:0030581
term: symbiont intracellular protein transport in host
ontology: BP
definition:
The directed movement of a symbiont's proteins within a cell of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0030582
term: reproductive fruiting body development
ontology: BP
definition:
The process whose specific outcome is the progression of a reproductive fruiting body over time, from its formation to the mature structure. A reproductive fruiting body is a multicellular reproductive structure that contains spores.


go_id: GO:0030583
term: myxococcal fruiting body development
ontology: BP
definition:
The process whose specific outcome is the progression of the myxococcal fruiting body over time, from its formation to the mature structure. The process begins when myxococci respond to a lack of nutrients in the environment and ends when the myxococcal fruiting body is a mature structure.


go_id: GO:0030584
term: sporocarp development
ontology: BP
definition:
The process whose specific outcome is the progression of a sporocarp over time, from its formation to the mature structure. The sporocarp is a spore bearing fruiting body organ. An example of this process is found in the Fungal species Coprinopsis cinerea.


go_id: GO:0030586
term: [methionine synthase] reductase activity
ontology: MF
definition:
Catalysis of the reaction: [methionine synthase]-cob(II)alamin + NADPH + H+ + S-adenosyl methionine = [methionine synthase]-methylcob(I)alamin + S-adenosylhomocysteine + NADP+.


go_id: GO:0030587
term: sorocarp development
ontology: BP
definition:
The process whose specific outcome is the progression of the sorocarp over time, from its formation to the mature structure. The process begins with the aggregation of individual cells and ends with the mature sorocarp. The sorocarp is a structure containing a spore-bearing sorus that sits on top of a stalk. An example of this process is found in Dictyostelium discoideum.


go_id: GO:0030588
term: pseudocleavage
ontology: BP
definition:
Partial constriction of the cytoplasm of a cell to form a furrow that resembles a cleavage furrow but does not complete cytokinesis.


go_id: GO:0030589
term: pseudocleavage involved in syncytial blastoderm formation
ontology: BP
definition:
Formation of furrows in the cytoplasm between nuclei during cell cycles in embryos that contribute to the formation of the syncytial blastoderm. An example of this process is found in Drosophila melanogaster.


go_id: GO:0030590
term: first cell cycle pseudocleavage
ontology: BP
definition:
A process that occurs during the first cell cycle in an embryo, in which anterior cortical contractions culminate in a single partial constriction of the embryo called the pseudocleavage furrow. An example of this process is found in nematode worms.


go_id: GO:0030591
term: 2'-deoxyguanosine DNA ADP-ribosyltransferase activity
ontology: MF
definition:
Catalysis of the transfer of the ADP-ribose group of NAD+ to the amino group at N2 of 2'-deoxyguanosine to yield N2-(alpha-ADP-ribos-1-yl)-2'-deoxyguanosine and its beta form.


go_id: GO:0030593
term: neutrophil chemotaxis
ontology: BP
definition:
The directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.


go_id: GO:0030594
term: neurotransmitter receptor activity
ontology: MF
definition:
Combining with a neurotransmitter and transmitting the signal to initiate a change in cell activity.


go_id: GO:0030596
term: alpha-L-rhamnosidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of terminal non-reducing alpha-L-rhamnose residues in alpha-L-rhamnosides.


go_id: GO:0030598
term: rRNA N-glycosylase activity
ontology: MF
definition:
Catalysis of the hydrolysis of the N-glycosylic bond at A-4324 in 28S rRNA from rat ribosomes or corresponding sites in 28S RNA from other species.


go_id: GO:0030604
term: 1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ontology: MF
definition:
Catalysis of the reaction: 2-C-methyl-D-erythritol 4-phosphate + NADP(+) = 1-deoxy-D-xylulose 5-phosphate + H(+) + NADPH.


go_id: GO:0030612
term: arsenate reductase (thioredoxin) activity
ontology: MF
definition:
Catalysis of the reaction: arsenate + thioredoxin = arsenite + thioredoxin disulfide. Thioredoxin disulfide is also known as oxidized thioredoxin.


go_id: GO:0030613
term: oxidoreductase activity, acting on phosphorus or arsenic in donors
ontology: MF
definition:
Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.


go_id: GO:0030614
term: oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor
ontology: MF
definition:
Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a disulfide.


go_id: GO:0030631
term: pyrrolysine incorporation
ontology: BP
definition:
The incorporation of pyrrolysine, also known as lysine methylamine methyltransferase cofactor adduct, into a peptide; uses a special tRNA that recognizes the UAG codon as a modified lysine, rather than as a termination codon. Pyrrolysine may be synthesized as a free amino acid or synthesized from a lysine charged tRNA before its incorporation; it is not a posttranslational modification of peptidyl-lysine; this modification is found in several Methanosarcina methylamine methyltransferases.


go_id: GO:0030632
term: D-alanine biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of D-alanine, the D-enantiomer of the amino acid alanine, i.e (2R)-2-aminopropanoic acid.


go_id: GO:0030633
term: D-alanine family amino acid catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of D-alanine and related amino acids.


go_id: GO:0030634
term: carbon fixation by acetyl-CoA pathway
ontology: BP
definition:
A pathway of carbon dioxide fixation in which one molecule of acetyl-CoA is completely synthesized from two molecules of carbon dioxide (CO2).


go_id: GO:0030638
term: polyketide metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps.


go_id: GO:0030639
term: polyketide biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps.


go_id: GO:0030640
term: polyketide catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps.


go_id: GO:0030641
term: regulation of cellular pH
ontology: BP
definition:
Any process involved in the maintenance of an internal equilibrium of hydrogen ions (protons) within a cell or between a cell and its external environment.


go_id: GO:0030642
term: cellular sulfate ion homeostasis
ontology: BP
definition:
Any process involved in the maintenance of an internal steady state of sulfate ions at the level of a cell.


go_id: GO:0030643
term: cellular phosphate ion homeostasis
ontology: BP
definition:
Any process involved in the maintenance of an internal steady state of phosphate ions at the level of a cell.


go_id: GO:0030644
term: cellular chloride ion homeostasis
ontology: BP
definition:
Any process involved in the maintenance of an internal steady state of chloride ions at the level of a cell.


go_id: GO:0030645
term: glucose catabolic process to butyrate
ontology: BP
definition:
The anaerobic chemical reactions and pathways resulting in the breakdown of glucose, with the production of acetic acid, butyric acid, carbon dioxide (CO2), and dihydrogen; effected by some saccharolytic species of Clostridium, e.g. C. butyricum.


go_id: GO:0030647
term: aminoglycoside antibiotic metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving an aminoglycoside antibiotic, any member of a group of broad spectrum antibiotics, of similar toxicity and pharmacology, that contain an aminodeoxysugar, an amino- or guanidino-substituted inositol ring, and one or more residues of other sugars. The group includes streptomycin, neomycin, framycetin, kanamycin, paromomycin, and gentamicin.


go_id: GO:0030648
term: aminoglycoside antibiotic biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of an aminoglycoside antibiotic, any member of a group of broad spectrum antibiotics, of similar toxicity and pharmacology, that contain an aminodeoxysugar, an amino- or guanidino-substituted inositol ring, and one or more residues of other sugars. The group includes streptomycin, neomycin, framycetin, kanamycin, paromomycin, and gentamicin.


go_id: GO:0030649
term: aminoglycoside antibiotic catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of an aminoglycoside antibiotic, any member of a group of broad spectrum antibiotics, of similar toxicity and pharmacology, that contain an aminodeoxysugar, an amino- or guanidino-substituted inositol ring, and one or more residues of other sugars. The group includes streptomycin, neomycin, framycetin, kanamycin, paromomycin, and gentamicin.


go_id: GO:0030651
term: peptide antibiotic biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of peptides with antibiotic activity.


go_id: GO:0030652
term: peptide antibiotic catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of peptides with antibiotic activity.


go_id: GO:0030653
term: beta-lactam antibiotic metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving a beta-lactam antibiotic, any member of a class of natural or semisynthetic antibiotics whose characteristic feature is a strained, four-membered beta-lactam ring. They include the penicillins and many of the cephalosporins.


go_id: GO:0030654
term: beta-lactam antibiotic biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a beta-lactam antibiotic, any member of a class of natural or semisynthetic antibiotics whose characteristic feature is a strained, four-membered beta-lactam ring. They include the penicillins and many of the cephalosporins.


go_id: GO:0030655
term: beta-lactam antibiotic catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of a beta-lactam antibiotic, any member of a class of natural or semisynthetic antibiotics whose characteristic feature is a strained, four-membered beta-lactam ring. They include the penicillins and many of the cephalosporins.


go_id: GO:0030656
term: regulation of vitamin metabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.


go_id: GO:0030673
term: axolemma
ontology: CC
definition:
The portion of the plasma membrane surrounding an axon; it is a specialized trilaminar random mosaic of protein molecules floating within a fluid matrix of highly mobile phospholipid molecules, 7-8 nm in thickness.


go_id: GO:0030674
term: protein-macromolecule adaptor activity
ontology: MF
definition:
The binding activity of a protein that brings together two or more macromolecules in contact, permitting those molecules to function in a coordinated way. The adaptor can bring together two proteins, or a protein and another macromolecule such as a lipid or a nucleic acid.


go_id: GO:0030677
term: ribonuclease P complex
ontology: CC
definition:
A ribonucleoprotein complex that catalyzes cleavage of the leader sequence of precursor tRNAs (pre-tRNAs), generating the mature 5' end of tRNAs.


go_id: GO:0030678
term: mitochondrial ribonuclease P complex
ontology: CC
definition:
A ribonuclease P complex located in the mitochondrion of a eukaryotic cell, where it catalyzes the 5' endonucleolytic cleavage of precursor tRNAs to yield mature tRNAs. The subunit composition of mitochondrial ribonuclease P complexes varies between species. The complex contains a single RNA molecule and a single protein molecule in yeast (PMID:12045094), but comprises three proteins and lacks an RNA component in humans.


go_id: GO:0030679
term: cyanelle ribonuclease P complex
ontology: CC
definition:
A ribonuclease P complex located in the cyanelle, where it catalyzes the 5' endonucleolytic cleavage of precursor tRNAs to yield mature tRNAs. The best characterized cyanelle ribonuclease P complex, from the alga Cyanophora paradoxa, contains a single RNA molecule that is necessary but not sufficient for catalysis, and several protein molecules.


go_id: GO:0030680
term: dimeric ribonuclease P complex
ontology: CC
definition:
A ribonuclease P complex that contains a single RNA molecule that is necessary and usually sufficient for catalysis, and a single protein molecule. Examples of this complex are found in Bacterial species.


go_id: GO:0030681
term: multimeric ribonuclease P complex
ontology: CC
definition:
A ribonuclease P complex that generally contains a single RNA molecule and several protein molecules. Examples of this complex are found in Archaeal species.


go_id: GO:0030682
term: mitigation of host defenses by symbiont
ontology: BP
definition:
A process by which an organism avoids or tolerates the effects of its host organism's defense response. The host defense response is mounted by the host in response to the presence of the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0030684
term: preribosome
ontology: CC
definition:
Any complex of pre-rRNAs, ribosomal proteins, and associated proteins formed during ribosome biogenesis.


go_id: GO:0030685
term: nucleolar preribosome
ontology: CC
definition:
Any complex of pre-rRNAs, ribosomal proteins, and associated proteins formed in the nucleolus during ribosome biogenesis.


go_id: GO:0030686
term: 90S preribosome
ontology: CC
definition:
A large ribonucleoprotein complex considered to be the earliest preribosomal complex. In S. cerevisiae, it has a size of 90S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins.


go_id: GO:0030687
term: preribosome, large subunit precursor
ontology: CC
definition:
A preribosomal complex consisting of 27SA, 27SB, and/or 7S pre-rRNA, 5S rRNA, ribosomal proteins including late-associating large subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic large ribosomal subunit.


go_id: GO:0030688
term: preribosome, small subunit precursor
ontology: CC
definition:
A preribosomal complex consisting of 20S pre-rRNA, ribosomal proteins including late-associating small subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic small ribosomal subunit.


go_id: GO:0030689
term: Noc complex
ontology: CC
definition:
Any of several heterodimers containing one or two Noc proteins, associated with preribosomal complexes; involved in ribosome biogenesis.


go_id: GO:0030690
term: Noc1p-Noc2p complex
ontology: CC
definition:
A heterodimer associated with 90S and 66S preribosomes. Predominantly, but not exclusively, nucleolar; involved in ribosomal large subunit biogenesis.


go_id: GO:0030691
term: Noc2p-Noc3p complex
ontology: CC
definition:
A heterodimer associated with 66S preribosomes; predominantly nucleoplasmic, but also locates to the nucleolus; involved in ribosomal large subunit biogenesis.


go_id: GO:0030692
term: Noc4p-Nop14p complex
ontology: CC
definition:
A heterodimer associated with precursors of the eukaryotic small ribosomal subunit, including the 90S preribosome; involved in small subunit biogenesis.


go_id: GO:0030694
term: bacterial-type flagellum basal body, rod
ontology: CC
definition:
The central portion of the bacterial-type flagellar basal body, which spans the periplasm and threads through the rings.


go_id: GO:0030696
term: tRNA (m5U54) methyltransferase activity
ontology: MF
definition:
Catalysis of the transfer of a methyl group from a donor to the C5 atom of the uridine residue at position 54 in a tRNA molecule.


go_id: GO:0030697
term: S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing thymine at position U54 of a transfer RNA. This occurs in most Gram-negative bacteria, some archae, and eukaryotes.


go_id: GO:0030698
term: 5,10-methylenetetrahydrofolate-dependent tRNA (m5U54) methyltransferase activity
ontology: MF
definition:
Catalysis of the transfer of a methyl group from 5,10-methylenetetrahydrofolate to the C5 atom of the uridine residue at position 54 in a tRNA molecule. This occurs in most Gram-positive bacteria and some Gram-negative bacteria.


go_id: GO:0030699
term: glycine reductase activity
ontology: MF
definition:
Catalysis of the reaction: acetyl phosphate + H(2)O + NH(4)(+) + thioredoxin disulfide = glycine + H(+) + phosphate + thioredoxin.


go_id: GO:0030700
term: glycine reductase complex
ontology: CC
definition:
Complex that possesses glycine reductase activity; usually comprises three subunits, of which two are selenoproteins; the subunits are typically designated selenoprotein A, selenoprotein B and protein C.


go_id: GO:0030701
term: NAD+-dinitrogen-reductase ADP-D-ribosyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: NAD+ + [dinitrogen reductase] = nicotinamide + ADP-D-ribosyl-[dinitrogen reductase].


go_id: GO:0030703
term: eggshell formation
ontology: BP
definition:
Construction of the eggshell, a product of the somatic follicle cell epithelium and a structure that supports the egg in a hostile environment, minimizing water loss whilst allowing gas exchanges essential for embryonic respiration.


go_id: GO:0030704
term: vitelline membrane formation
ontology: BP
definition:
Construction of the vitelline membrane portion of the egg shell, a rigid structure required to maintain the shape of the egg.


go_id: GO:0030705
term: cytoskeleton-dependent intracellular transport
ontology: BP
definition:
The directed movement of substances along cytoskeletal fibers such as microfilaments or microtubules within a cell.


go_id: GO:0030706
term: germarium-derived oocyte differentiation
ontology: BP
definition:
The process in which one relatively unspecialized immature cystocyte of the germ-line cyst in the germarium acquires the specialized features of an oocyte. An example of this process can be found in Drosophila melanogaster.


go_id: GO:0030707
term: ovarian follicle cell development
ontology: BP
definition:
The process that occurs during oogenesis involving the ovarian follicle cells, somatic cells which surround the germ cells of an ovary. An example of this is found in Drosophila melanogaster.


go_id: GO:0030708
term: germarium-derived female germ-line cyst encapsulation
ontology: BP
definition:
Formation of a single follicular epithelium around the germ-line derived cells of a cyst formed in the germarium. An example of this process is found in Drosophila melanogaster.


go_id: GO:0030709
term: border follicle cell delamination
ontology: BP
definition:
The delamination process that results in the splitting off of border cells from the anterior epithelium, prior to border cell migration.


go_id: GO:0030713
term: ovarian follicle cell stalk formation
ontology: BP
definition:
Development of ovarian follicle cells to create the interfollicular stalks that connect the egg chambers of progressive developmental stages. An example of this process is found in Drosophila melanogaster.


go_id: GO:0030715
term: oocyte growth in germarium-derived egg chamber
ontology: BP
definition:
The increase in volume of an oocyte during the growth phase of the egg chamber, once the egg chamber has left the germarium. An example of this process is found in Drosophila melanogaster.


go_id: GO:0030716
term: oocyte fate determination
ontology: BP
definition:
The process in which a cell becomes capable of differentiating autonomously into an oocyte cell regardless of its environment; upon determination, the cell fate cannot be reversed.


go_id: GO:0030717
term: oocyte karyosome formation
ontology: BP
definition:
The chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome.


go_id: GO:0030719
term: P granule organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of polar granules, cytoplasmic, non-membranous RNA/protein complex aggregates in the primordial germ cells of many higher eukaryotes.


go_id: GO:0030720
term: oocyte localization involved in germarium-derived egg chamber formation
ontology: BP
definition:
Directed movement of the oocyte, following its specification, from its original central position in the cyst to a posterior position relative to the nurse cells of the egg chamber, and its maintenance in this posterior location. This is the first sign of anterior-posterior asymmetry in the developing egg chamber.


go_id: GO:0030721
term: spectrosome organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spectrosome, a germline specific spherical organelle that is the precursor to the fusome.


go_id: GO:0030723
term: ovarian fusome organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fusome of ovarian cells, an organelle derived from the spectrosome. It anchors the mitotic spindle pole to provide orientation during cystoblast cell divisions.


go_id: GO:0030724
term: testicular fusome organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fusome of testicular cells, an organelle derived from the spectrosome.


go_id: GO:0030727
term: germarium-derived female germ-line cyst formation
ontology: BP
definition:
Formation, in a germarium, of a group of interconnected cells derived from a single female gonial founder cell (a cystoblast). The germarium is the most anterior portion of an insect ovariole. An example of this process is found in Drosophila melanogaster.


go_id: GO:0030730
term: sequestering of triglyceride
ontology: BP
definition:
The process of binding or confining any triester of glycerol such that it is separated from other components of a biological system.


go_id: GO:0030731
term: guanidinoacetate N-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + guanidinoacetate = S-adenosyl-L-homocysteine + creatine + H(+).


go_id: GO:0030732
term: methionine S-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + L-methionine = S-adenosyl-L-homocysteine + S-methyl-L-methionine.


go_id: GO:0030733
term: fatty acid O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + a fatty acid = S-adenosyl-L-homocysteine + a fatty acid methyl ester.


go_id: GO:0030734
term: polysaccharide O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + 1,4-N1-D-glucooligosaccharide = S-adenosyl-L-homocysteine + oligosaccharide containing 6-methyl-D-glucose units.


go_id: GO:0030735
term: carnosine N-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + carnosine = S-adenosyl-L-homocysteine + anserine + H(+).


go_id: GO:0030736
term: phenol O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + phenol = S-adenosyl-L-homocysteine + anisole + H(+).


go_id: GO:0030737
term: iodophenol O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: 2-iodophenol + S-adenosyl-L-methionine = 1-iodo-2-methoxybenzene + S-adenosyl-L-homocysteine + H(+).


go_id: GO:0030738
term: tyramine N-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + tyramine = N-methyltyramine + S-adenosyl-L-homocysteine + H(+).


go_id: GO:0030739
term: O-demethylpuromycin O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + O-demethylpuromycin = S-adenosyl-L-homocysteine + puromycin.


go_id: GO:0030740
term: inositol 3-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine(1+) + myo-inositol = 1D-3-O-methyl-myo-inositol + S-adenosyl-L-homocysteine + H(+).


go_id: GO:0030741
term: inositol 1-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine(1+) + myo-inositol = 1D-1-O-methyl-myo-inositol + S-adenosyl-L-homocysteine + H(+).


go_id: GO:0030742
term: GTP-dependent protein binding
ontology: MF
definition:
Binding to a protein or protein complex when at least one of the interacting partners is in the GTP-bound state.


go_id: GO:0030743
term: rRNA (adenosine-2'-O-)-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing a single residue of 2'-O-methyladenosine.


go_id: GO:0030744
term: luteolin O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + luteolin = 4',5,7-trihydroxy-3'-methoxyflavone + S-adenosyl-L-homocysteine + H(+).


go_id: GO:0030745
term: dimethylhistidine N-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + N-alpha,N-alpha-dimethyl-L-histidine = S-adenosyl-L-homocysteine + N-alpha,N-alpha,N-alpha-trimethyl-L-histidine.


go_id: GO:0030746
term: isoflavone 4'-O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + isoflavone = S-adenosyl-L-homocysteine + 4'-O-methylisoflavone.


go_id: GO:0030747
term: indolepyruvate C-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + (indol-3-yl)pyruvate = S-adenosyl-L-homocysteine + (S)-3-(indol-3-yl)-2-oxobutanoate.


go_id: GO:0030748
term: amine N-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + an amine = S-adenosyl-L-homocysteine + a methylated amine.


go_id: GO:0030749
term: loganate O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + loganate = S-adenosyl-L-homocysteine + loganin.


go_id: GO:0030750
term: putrescine N-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + putrescine = N-methylputrescine + S-adenosyl-L-homocysteine + H(+).


go_id: GO:0030751
term: licodione 2'-O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine(1+) + licodione = 2'-O-methyllicodione + S-adenosyl-L-homocysteine + H(+).


go_id: GO:0030752
term: 5-hydroxyfuranocoumarin 5-O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + 5-hydroxyfuranocoumarin = S-adenosyl-L-homocysteine + 5-methoxyfuranocoumarin.


go_id: GO:0030753
term: 8-hydroxyfuranocoumarin 8-O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + xanthotoxol = S-adenosyl-L-homocysteine + xanthotoxin. Xanthotoxol is also known as 8-hydroxyfuranocoumarin and xanthotoxin as 8-methoxyfuranocoumarin.


go_id: GO:0030754
term: apigenin 4'-O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + 5,7,4'-trihydroxyflavone = S-adenosyl-L-homocysteine + 4'-methoxy-5,7-dihydroxyflavone.


go_id: GO:0030755
term: quercetin 3-O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxy-flavone.


go_id: GO:0030756
term: isoorientin 3'-O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine(1+) + isoorientin = S-adenosyl-L-homocysteine + H(+) + isoscoparin.


go_id: GO:0030757
term: 3-methylquercitin 7-O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: 3',4',5,7-tetrahydroxy-3-methoxyflavone + S-adenosyl-L-methionine(1+) = 3',4',5-trihydroxy-3,7-dimethoxyflavone + S-adenosyl-L-homocysteine.


go_id: GO:0030758
term: 3,7-dimethylquercitin 4'-O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: 3',4',5-trihydroxy-3,7-dimethoxyflavone + S-adenosyl-L-methionine(1+) = 3',5-dihydroxy-3,4',7-trimethoxyflavone + S-adenosyl-L-homocysteine + H(+).


go_id: GO:0030759
term: methylquercetagetin 6-O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: 3',4',5,6-tetrahydroxy-3,7-dimethoxyflavone + S-adenosyl-L-methionine(1+) = 3',4',5-trihydroxy-3,6,7-trimethoxyflavone + S-adenosyl-L-homocysteine + H(+).


go_id: GO:0030760
term: pyridine N-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine(1+) + pyridine = N-methylpyridinium + S-adenosyl-L-homocysteine.


go_id: GO:0030761
term: 8-hydroxyquercitin 8-O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: 3,3',4',5,7,8-hexahydroxyflavone + S-adenosyl-L-methionine(1+) = 3,3',4',5,7-pentahydroxy-8-methoxyflavone + S-adenosyl-L-homocysteine + H(+).


go_id: GO:0030762
term: tetrahydrocolumbamine 2-O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: (S)-tetrahydrocolumbamine + S-adenosyl-L-methionine(1+) = S-adenosyl-L-homocysteine + H(+) + tetrahydropalmatine.


go_id: GO:0030763
term: isobutyraldoxime O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: 2-methylpropanal oxime + S-adenosyl-L-methionine = 2-methylpropanal O-methyloxime + S-adenosyl-L-homocysteine + H(+).


go_id: GO:0030766
term: 11-O-demethyl-17-O-deacetylvindoline O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + 11-O-demethyl-17-O-deacetylvindoline = S-adenosyl-L-homocysteine + 17-O-deacetylvindoline.


go_id: GO:0030767
term: 3-hydroxyanthranilate 4-C-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: 3-hydroxyanthranilate + S-adenosyl-L-methionine = 3-hydroxy-4-methylanthranilate + S-adenosyl-L-homocysteine + H(+).


go_id: GO:0030768
term: 16-methoxy-2,3-dihydro-3-hydroxytabersonine N-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: (3R)-3-hydroxy-16-methoxy-2,3-dihydrotabersonine + S-adenosyl-L-methionine = S-adenosyl-L-homocysteine + deacetoxyvindoline + H(+).


go_id: GO:0030769
term: macrocin O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine(1+) + macrocin = S-adenosyl-L-homocysteine + H(+) + tylosin.


go_id: GO:0030770
term: demethylmacrocin O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine(1+) + demethylmacrocin = S-adenosyl-L-homocysteine + H(+) + macrocin.


go_id: GO:0030771
term: N-benzoyl-4-hydroxyanthranilate 4-O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: N-benzoyl-4-hydroxyanthranilate + S-adenosyl-L-methionine(1+) = N-benzoyl-4-methoxyanthranilate + S-adenosyl-L-homocysteine + H(+).


go_id: GO:0030772
term: tryptophan 2-C-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine(1+) + L-tryptophan = S-adenosyl-L-homocysteine + L-2-methyltryptophan + H(+).


go_id: GO:0030773
term: 6-hydroxymellein O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: 6-hydroxymellein + S-adenosyl-L-methionine = 6-methoxymellein + S-adenosyl-L-homocysteine + H(+).


go_id: GO:0030774
term: anthranilate N-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + anthranilate = N-methylanthranilate + S-adenosyl-L-homocysteine + H(+).


go_id: GO:0030775
term: glucuronoxylan 4-O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + glucuronoxylan D-glucuronate = S-adenosyl-L-homocysteine + glucuronoxylan 4-O-methyl-D-glucuronate.


go_id: GO:0030776
term: (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline = S-adenosyl-L-homocysteine + N-methyl-(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline.


go_id: GO:0030777
term: (S)-scoulerine 9-O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: (S)-scoulerine + S-adenosyl-L-methionine(1+) = (S)-tetrahydrocolumbamine + S-adenosyl-L-homocysteine + H(+).


go_id: GO:0030778
term: columbamine O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + columbamine = S-adenosyl-L-homocysteine + H(+) + palmatine.


go_id: GO:0030779
term: 10-hydroxydihydrosanguinarine 10-O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: 10-hydroxydihydrosanguinarine + S-adenosyl-L-methionine(1+) = S-adenosyl-L-homocysteine + dihydrochelirubine + H(+).


go_id: GO:0030780
term: 12-hydroxydihydrochelirubine 12-O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: 12-hydroxydihydrochelirubine + S-adenosyl-L-methionine(1+) = S-adenosyl-L-homocysteine + dihydromacarpine + H(+).


go_id: GO:0030781
term: 6-O-methylnorlaudanosoline 5'-O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + 6-O-methylnorlaudanosoline = S-adenosyl-L-homocysteine + nororientaline.


go_id: GO:0030782
term: (S)-tetrahydroprotoberberine N-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + (S)-7,8,13,14-tetrahydroprotoberberine = S-adenosyl-L-homocysteine + cis-N-methyl-(S)-7,8,13,14-tetrahydroprotoberberine.


go_id: GO:0030783
term: [cytochrome c]-methionine S-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + [cytochrome c]-methionine = S-adenosyl-L-homocysteine + [cytochrome c]-S-methyl-methionine.


go_id: GO:0030784
term: 3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + 3'-hydroxy-N-methyl-(S)-coclaurine = S-adenosyl-L-homocysteine + (S)-reticuline.


go_id: GO:0030785
term: [ribulose-bisphosphate carboxylase]-lysine N-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + [ribulose-1,5-bisphosphate carboxylase]-lysine = S-adenosyl-L-homocysteine + [ribulose-1,5-bisphosphate carboxylase]-N6-methyl-L-lysine.


go_id: GO:0030786
term: (RS)-norcoclaurine 6-O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + (RS)-norcoclaurine = S-adenosyl-L-homocysteine + (RS)-coclaurine.


go_id: GO:0030787
term: inositol 4-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine(1+) + myo-inositol = 1D-4-O-methyl-myo-inositol + S-adenosyl-L-homocysteine + H(+).


