# go_term

go_id: GO:0110064
term: lncRNA catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of lncRNAs, non-coding RNAs over 200 nucleotides in length.


go_id: GO:0110065
term: regulation of interphase mitotic telomere clustering
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of mitotic telomere clustering during interphase.


go_id: GO:0110066
term: negative regulation of interphase mitotic telomere clustering
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of mitotic telomere clustering during interphase.


go_id: GO:0110067
term: ammonium transmembrane transporter complex
ontology: CC
definition:
High affinity ammonium transporter complex that enables the transfer of ammonium from one side of a membrane to the other.


go_id: GO:0110070
term: cellularization cleavage furrow
ontology: CC
definition:
A plasma membrane invagination at the site of separation of a multi-nucleate cell or syncytium into individual cells.


go_id: GO:0110071
term: cellularization cleavage furrow invagination front
ontology: CC
definition:
The base of the cellularization invagination or cleavage furrow most distal to the original multi-nucleate cell or syncytium plasma membrane.


go_id: GO:0110072
term: apical constriction involved in ventral furrow formation
ontology: BP
definition:
The actin-mediated process that results in contraction of the apical end of a polarized columnar epithelial cell, contributing to formation of a ventral indentation (furrow) from the blastoderm epithelium, which is internalized to form a tube in the interior of the embryo, marking the start of gastrulation.


go_id: GO:0110073
term: regulation of apical constriction involved in ventral furrow formation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of apical constriction involved in ventral furrow formation.


go_id: GO:0110074
term: positive regulation of apical constriction involved in ventral furrow formation
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of apical constriction involved in ventral furrow formation.


go_id: GO:0110077
term: vesicle-mediated intercellular transport
ontology: BP
definition:
A cellular transport process in which transported substances are moved in extracellular vesicles between cells; transported substances are enclosed in the vesicle lumen or located in the extracellular vesicle membrane.


go_id: GO:0110078
term: TTT complex
ontology: CC
definition:
A protein complex responsible for the stabilisation of protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex can also be found as part of the ASTRA complex (GO:0070209).


go_id: GO:0110080
term: positive regulation of placenta blood vessel development
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of placenta blood vessel development.


go_id: GO:0110081
term: negative regulation of placenta blood vessel development
ontology: BP
definition:
Any process that stops, prevents or reduces the frequency, rate or extent of placenta blood vessel development.


go_id: GO:0110082
ontology: BP
term:
regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly

definition:
Any process that modulates the frequency, rate or extent of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly.


go_id: GO:0110083
ontology: BP
term:
positive regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly

definition:
Any process that activates or increases the frequency, rate or extent of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly.


go_id: GO:0110084
ontology: BP
term:
negative regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly

definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly.


go_id: GO:0110085
term: mitotic actomyosin contractile ring
ontology: CC
definition:
A cytoskeletal structure composed of actin filaments, myosin, and myosin-associated proteins that forms beneath the plasma membrane of many cells, including animal cells and yeast cells, in a plane perpendicular to the axis of the mitotic spindle, i.e. the cell division plane. Ring contraction is associated with centripetal growth of the membrane that divides the cytoplasm of the two future daughter cells. In animal cells, the mitotic contractile ring is located inside the plasma membrane at the location of the cleavage furrow. In budding fungal cells, e.g. mitotic S. cerevisiae cells, the mitotic contractile ring forms beneath the plasma membrane at the mother-bud neck before mitosis.


go_id: GO:0110086
term: meiotic actomyosin contractile ring
ontology: CC
definition:
A cytoskeletal structure composed of actin filaments, myosin, and myosin-associated proteins that forms beneath the plasma membrane of many cells, including animal cells and yeast cells, in a plane perpendicular to the axis of the meiotic spindle, i.e. the cell division plane. Ring contraction is associated with centripetal growth of the membrane that divides the cytoplasm of the two future daughter cells. In animal cells, the meiotic contractile ring is located inside the plasma membrane at the location of the cleavage furrow. In fungal cells, the meiotic contractile ring forms beneath the plasma membrane of the prospore envelope in preparation for completing cytokinesis.


go_id: GO:0110089
term: regulation of hippocampal neuron apoptotic process
ontology: BP
definition:
Any process that modulates the occurrence or rate of cell death by apoptotic process in hippocampal neurons.


go_id: GO:0110090
term: positive regulation of hippocampal neuron apoptotic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process in hippocampal neurons.


go_id: GO:0110091
term: negative regulation of hippocampal neuron apoptotic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in hippocampal neurons.


go_id: GO:0110094
term: polyphosphate-mediated signaling
ontology: BP
definition:
Any process that mediates the transfer of information from one cell to another using polyphosphate as the signal.


go_id: GO:0110095
term: cellular detoxification of aldehyde
ontology: BP
definition:
Any process carried out at the cellular level that reduces or removes the toxicity of an aldehyde. These may include transport of aldehydes away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.


go_id: GO:0110096
term: cellular response to aldehyde
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldehyde stimulus.


go_id: GO:0110098
term: positive regulation of calcium import into the mitochondrion
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of calcium import into the mitochondrion.


go_id: GO:0110099
term: negative regulation of calcium import into the mitochondrion
ontology: BP
definition:
Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import into the mitochondrion.


go_id: GO:0110100
term: spindle pole body separation
ontology: BP
definition:
The release of duplicated spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane. Duplicated SPBs are connected by a bridge structure that is severed in order to release the SPBs from one another. Following liberation, SPBs diffuse through the nuclear membrane until they are across from each other. SPB separation must take place in order for a bipolar spindle to assemble.


go_id: GO:0110102
term: ribulose bisphosphate carboxylase complex assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form a ribulose bisphosphate carboxylase complex.


go_id: GO:0110103
term: RNA polymerase II termination complex
ontology: CC
definition:
A conserved protein complex capable of 5'-3' exoribonuclease activity. It is able to promote RNA polymerase II (RNAPII) transcription termination by degrading pre-mRNA from the newly formed 5' phosphorylated end.


go_id: GO:0110104
term: mRNA alternative polyadenylation
ontology: BP
definition:
The process of generating multiple mRNA molecules with variable 3'-end length formation from a given pre-mRNA by differential use of cleavage and polyadenylation signals (pA signals).


go_id: GO:0110105
term: mRNA cleavage and polyadenylation specificity factor complex assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form the mRNA cleavage and polyadenylation specificity factor complex.


go_id: GO:0110107
term: regulation of imaginal disc-derived wing vein specification
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of imaginal disc-derived wing vein specification.


go_id: GO:0110108
term: positive regulation of imaginal disc-derived wing vein specification
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of imaginal disc-derived wing vein specification.


go_id: GO:0110109
term: negative regulation of imaginal disc-derived wing vein specification
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc-derived wing vein specification.


go_id: GO:0110110
term: positive regulation of animal organ morphogenesis
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of animal organ morphogenesis.


go_id: GO:0110111
term: negative regulation of animal organ morphogenesis
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of animal organ morphogenesis.


go_id: GO:0110115
term: Cdr2 medial cortical node complex
ontology: CC
definition:
A megadalton-sized complex at the medial cortex organized as an oligomeric core of SAD family protein kinases involved in cell size-dependent localization and phosphorylation of Wee1 during interphase.


go_id: GO:0110116
term: regulation of compound eye photoreceptor cell differentiation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of compound eye photoreceptor cell differentiation.


go_id: GO:0110117
term: positive regulation of compound eye photoreceptor cell differentiation
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of compound eye photoreceptor cell differentiation.


go_id: GO:0110118
term: negative regulation of compound eye photoreceptor cell differentiation
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of compound eye photoreceptor cell differentiation.


go_id: GO:0110119
term: positive regulation of very-low-density lipoprotein particle clearance
ontology: BP
definition:
Any process that increases the frequency, rate or extent of very-low-density lipoprotein particle clearance.


go_id: GO:0110120
term: gamma-tubulin complex localization to nuclear side of mitotic spindle pole body
ontology: BP
definition:
Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location at the nuclear side of the mitotic spindle pole body.


go_id: GO:0110121
term: gamma-tubulin complex localization to cytoplasmic side of mitotic spindle pole body
ontology: BP
definition:
Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location at the cytoplasmic side of the mitotic spindle pole body.


go_id: GO:0110122
term: myotube cell migration
ontology: BP
definition:
The orderly movement of a myotube cell from one site to another, often during the development of a multicellular organism. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate, and fuse.


go_id: GO:0110124
term: positive regulation of myotube cell migration
ontology: BP
definition:
Any process that activates, maintains or increases the frequency, rate or extent of myotube cell migration.


go_id: GO:0110125
term: negative regulation of myotube cell migration
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of myotube cell migration.


go_id: GO:0110126
term: phloem loading
ontology: BP
definition:
The process of loading solutes into the sieve tube or companion cell of the phloem for long distance transport from source to sink.


go_id: GO:0110127
term: phloem unloading
ontology: BP
definition:
The process of unloading solutes that are produced in the source tissues, from the sieve tube or companion cell of the phloem into the sink tissues.


go_id: GO:0110128
term: phloem sucrose unloading
ontology: BP
definition:
The process of unloading sucrose that is produced in the source tissues, from the sieve tube or companion cell of the phloem into the sink tissues.


go_id: GO:0110129
term: SHREC2 complex
ontology: CC
definition:
A histone deacetylase complex formed by the association of an HP1 protein with a SHREC complex. The SHREC2 complex is required for deacetylation of H3K14, and mediates transcriptional gene silencing by limiting RNA polymerase II access to heterochromatin. In fission yeast, the complex contains the SHREC subunits Clr1, Clr2, Clr3, and Mit1, and the HP1 protein Chp2.


go_id: GO:0110131
term: Aim21-Tda2 complex
ontology: CC
definition:
A complex that localizes to actin cortical patches at sites of endocytosis and negatively regulates barbed end F-actin assembly, resulting in the generation of free actin pools. The Aim21-Tda2 complex is necessary for efficient endocytosis and balancing the distribution of actin between patches and cables.


go_id: GO:0110134
term: meiotic drive
ontology: BP
definition:
A biological process that results in the unequal transmission of alleles, haplotypes, or chromosomes from a parental genome to gametes. In the absence of meiotic drive, the two copies of each gene or chromosome in a diploid organism are transmitted to offspring with equal probability, whereas meiotic drive results in overrepresentation of the driving allele among the surviving products of meiosis.


go_id: GO:0110135
term: Norrin signaling pathway
ontology: BP
definition:
The series of molecular signals initiated by binding of the cysteine knot protein Norrin to a Frizzled 4 (Fzd4) family receptor on the surface of the target cell and ending with a change in cell state.


go_id: GO:0110136
term: protein-RNA complex remodeling
ontology: BP
definition:
The acquisition, loss, or modification of macromolecules within a protein-RNA complex, resulting in the alteration of an existing complex.


go_id: GO:0110137
term: regulation of imaginal disc-derived leg joint morphogenesis
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis, the process in which the anatomical structure of the imaginal disc-derived leg joint is generated and organized.


go_id: GO:0110138
term: positive regulation of imaginal disc-derived leg joint morphogenesis
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis.


go_id: GO:0110139
term: negative regulation of imaginal disc-derived leg joint morphogenesis
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis.


go_id: GO:0110140
term: flagellum attachment zone organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a flagellum attachment zone. FAZ is a network of cytoskeletal and membranous connections responsible for the lateral attachment of the cilium to the cell body in some trypanosomatid species.


go_id: GO:0110142
term: ubiquinone biosynthesis complex
ontology: CC
definition:
The cytosolic ubiquinone biosynthesis complex is composed of enzymes and accessory factors of the ubiquinone biosynthesis pathway and enables synthesis of the extremely hydrophobic molecule ubiquinone. In E. coli, the complex is composed of seven proteins: UbiE, F, G, H, I, J and K.


go_id: GO:0110143
term: magnetosome
ontology: CC
definition:
A membrane-bound organelle that envelops particles of magnetic iron minerals in magnetotactic bacteria. Magnetosomes form linear chains that align along the cellular motility axis at midcell and function in bacterial navigation along the Earth's magnetic field. They are formed by invagination of the cell inner membrane; in some species they remain connected to the inner membrane, in others they pinch off to form independent intracellular vesicles.


go_id: GO:0110147
term: protein maturation by nickel ion transfer
ontology: BP
definition:
A process that contributes to the delivery of nickel ions to a target protein to facilitate its maturation.


go_id: GO:0110148
term: biomineralization
ontology: BP
definition:
The process where mineral crystals are formed and deposited in an organized fashion in a matrix (either cellular or extracellular) by living organisms. This gives rise to inorganic compound-based structures such as skeleton, teeth, ivory, shells, cuticle, and corals as well as bacterial biomineralization products.


go_id: GO:0110149
term: regulation of biomineralization
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of biomineralization, the formation and deposition of mineral crystals by living organisms.


go_id: GO:0110150
term: negative regulation of biomineralization
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of biomineralization, the formation and deposition of mineral crystals by living organisms.


go_id: GO:0110151
term: positive regulation of biomineralization
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of biomineralization, the formation and deposition of mineral crystals by living organisms.


go_id: GO:0110152
term: RNA NAD-cap (NAD-forming) hydrolase activity
ontology: MF
definition:
Catalysis of the reaction: a 5'-end NAD(+)-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-ribonucleoside in mRNA + H(+) + NAD(+).


go_id: GO:0110153
term: RNA NAD-cap (NMN-forming) hydrolase activity
ontology: MF
definition:
Catalysis of the reaction: a 5'-end NAD(+)-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-adenosine-phospho-ribonucleoside in mRNA + beta-nicotinamide D-ribonucleotide + 2 H(+).


go_id: GO:0110155
term: NAD-cap decapping
ontology: BP
definition:
Cleavage of the 5'-NAD-cap of an RNA. The NAD-cap is present at the 5'-end of some RNAs in both bacetria and eukaryotes. While it promotes RNA stability in bacteria, it promotes RNA decay in eukaryotes.


go_id: GO:0110156
term: methylguanosine-cap decapping
ontology: BP
definition:
Cleavage of the 5'-methylguanosine-cap of an mRNA. The methylguanosine-cap is present at the 5'-end of eukaryotic mRNAs. Decapping inactivates translation initiation and promotes 5'-to-3' decay of mRNA.


go_id: GO:0110157
term: reelin complex
ontology: CC
definition:
An extracellular complex that binds lipoprotein receptors VLDLR and APOER2, cadherin-related neuronal receptors (CNRs) or alpha3beta1 integrin and induces various downstream, reelin-dependent, phosphorylation cascades. It ultimately affects polarization, differentiation, neuronal migration and layer formation in the embryonic brain and neuron growth, maturation, and synaptic activity in the postnatal and adult brain.


go_id: GO:0110158
term: calpain complex
ontology: CC
definition:
A calcium-dependent protease complex that processes its substrate by limited proteolysis rather than degrading it. In some cases limited proteolysis is required for the activation of its substrate.


go_id: GO:0110159
term: regulation of mitotic spindle formation (spindle phase one)
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase one).


go_id: GO:0110160
term: negative regulation of mitotic spindle formation (spindle phase one)
ontology: BP
definition:
Any process that stops, prevents or reduces the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase one).


go_id: GO:0110161
term: positive regulation of mitotic spindle formation (spindle phase one)
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase one).


go_id: GO:0110162
term: regulation of mitotic spindle elongation (spindle phase three)
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic anaphase B (spindle phase three).


go_id: GO:0110163
term: negative regulation of mitotic spindle elongation (spindle phase three)
ontology: BP
definition:
Any process that stops, prevents or reduces the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic anaphase B (spindle phase three).


go_id: GO:0110164
term: positive regulation of mitotic spindle elongation (spindle phase three)
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic anaphase B (spindle phase three).


go_id: GO:0110165
term: cellular anatomical entity
ontology: CC
definition:
A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex.


go_id: GO:0120001
term: apical plasma membrane urothelial plaque
ontology: CC
definition:
A scallop-shaped plaque, also referred to as an asymmetric unit membrane (AUM), found in the apical plasma membrane of urothelial superficial (umbrella) cells which form a a barrier to the passage of water and soluble toxic compounds found in urine. The plaques are thickened regions of membrane composed of uroplakin transmembrane proteins which form a crystalline array.


go_id: GO:0120002
term: fusiform vesicle
ontology: CC
definition:
A cytoplasmic vesicle which contains two urothelial plaques and can deliver these plaques to the apical plasma membrane of urothelial superficial (umbrella) cells. It can also be formed by endocytosis of apical plasma membrane during contractions of the urinary bladder.


go_id: GO:0120007
term: negative regulation of glutamatergic neuron differentiation
ontology: BP
definition:
Any process that stops, prevents or reduces the frequency, rate or extent of glutamatergic neuron differentiation.


go_id: GO:0120008
term: positive regulation of glutamatergic neuron differentiation
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of glutamatergic neuron differentiation.


go_id: GO:0120009
term: intermembrane lipid transfer
ontology: BP
definition:
The transport of lipids between membranes in which a lipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs).


go_id: GO:0120010
term: intermembrane phospholipid transfer
ontology: BP
definition:
The transport of phospholipids between membranes in which a phospholipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane.


go_id: GO:0120011
term: intermembrane sterol transfer
ontology: BP
definition:
The transport of sterols between membranes in which a sterol molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs).


go_id: GO:0120012
term: intermembrane sphingolipid transfer
ontology: BP
definition:
The transport of sphingolipids between membranes in which a sphingolipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs).


go_id: GO:0120013
term: lipid transfer activity
ontology: MF
definition:
Removes a lipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. This results in intermembrane transfer of lipids.


go_id: GO:0120014
term: phospholipid transfer activity
ontology: MF
definition:
Removes a phospholipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.


go_id: GO:0120015
term: sterol transfer activity
ontology: MF
definition:
Removes a sterol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.


go_id: GO:0120016
term: sphingolipid transfer activity
ontology: MF
definition:
Removes a sphingolipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.


go_id: GO:0120017
term: ceramide transfer activity
ontology: MF
definition:
Removes a ceramide from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.


go_id: GO:0120019
term: phosphatidylcholine transfer activity
ontology: MF
definition:
Removes phosphatidylcholine from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.


go_id: GO:0120020
term: cholesterol transfer activity
ontology: MF
definition:
Removes cholesterol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.


go_id: GO:0120021
term: oxysterol transfer activity
ontology: MF
definition:
Removes oxysterol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.


go_id: GO:0120022
term: glucagon family peptide binding
ontology: MF
definition:
Binding to a member of the glucagon family peptide hormone (e.g. glucagon, glucagon-like peptides, oxyntomodulin, glicentin, ADCYAP1, GHRH, secretin, VIP, GIP).


go_id: GO:0120023
term: somatostatin binding
ontology: MF
definition:
Binding to somatostatin, a polypeptide hormone involved in regulating pancreatic alpha and pancreatic beta cells and controlling growth hormone secretion as well as many other functions. Somatostatin is produced by several cell types including pancreatic delta cells. There are several different mature forms of somatostatin.


go_id: GO:0120025
term: plasma membrane bounded cell projection
ontology: CC
definition:
A prolongation or process extending from a cell and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon.


go_id: GO:0120026
term: host cell uropod
ontology: CC
definition:
A host cell membrane projection with related cytoskeletal components at the trailing edge of a cell in the process of migrating or being activated, found on the opposite side of the cell from the leading edge or immunological synapse, respectively.


go_id: GO:0120028
term: negative regulation of osmosensory signaling pathway
ontology: BP
definition:
Any process that stops, prevents or reduces the frequency, rate or extent of osmosensory signaling pathway.


go_id: GO:0120029
term: proton export across plasma membrane
ontology: BP
definition:
The directed movement of hydrogen ions (protons) from inside a cell, across the plasma membrane and into the extracellular region.


go_id: GO:0120030
term: positive regulation of cilium beat frequency involved in ciliary motility
ontology: BP
definition:
Any process that activates or increases the frequency of cilium beating involved in ciliary motility.


go_id: GO:0120031
term: plasma membrane bounded cell projection assembly
ontology: BP
definition:
Formation of a prolongation or process extending and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon.


go_id: GO:0120032
term: regulation of plasma membrane bounded cell projection assembly
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of plasma membrane bounded cell projection assembly.


go_id: GO:0120033
term: negative regulation of plasma membrane bounded cell projection assembly
ontology: BP
definition:
Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane bounded cell projection assembly.


go_id: GO:0120034
term: positive regulation of plasma membrane bounded cell projection assembly
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of plasma membrane bounded cell projection assembly.


go_id: GO:0120035
term: regulation of plasma membrane bounded cell projection organization
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of plasma membrane bounded cell projections.


go_id: GO:0120036
term: plasma membrane bounded cell projection organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasma membrane bounded prolongation or process extending from a cell, e.g. a cilium or axon.


go_id: GO:0120039
term: plasma membrane bounded cell projection morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of a plasma membrane bounded cell projection are generated and organized.


go_id: GO:0120042
term: negative regulation of macrophage proliferation
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage proliferation.


go_id: GO:0120043
term: stereocilium shaft
ontology: CC
definition:
The shaft comprises the majority of the length of the stereocilium. This region is notable for the extreme stability of actin filaments, which are highly crosslinked into a parallel bundle.


go_id: GO:0120044
term: stereocilium base
ontology: CC
definition:
The tapered base of the stereocilium adjacent to where it joins the hair cell body. This region contains a rootlet comprised of bundled actin filaments which spans the joint and stabilizes the stereocilium.


go_id: GO:0120046
term: regulation of protein localization to medial cortical node
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of protein localization to a medial cortical node.


go_id: GO:0120047
term: positive regulation of protein localization to medial cortical node
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of protein localization to a medial cortical node.


go_id: GO:0120048
term: U6 snRNA (adenine-(43)-N(6))-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + adenine(43) in U6 snRNA = S-adenosyl-L-homocysteine + N(6)-methyladenine(43) in U6 snRNA.


go_id: GO:0120053
term: ribitol beta-1,4-xylosyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: UDP-D-xylose + D-ribitol 5-phosphate-R = UDP + beta1,4-xylosyl-D-ribitol 5-phosphate-R.


go_id: GO:0120054
term: intestinal motility
ontology: BP
definition:
Contractions of the intestinal tract that include peristalsis (moving contents onward) and non-peristaltic movement (moving contents back and forth).


go_id: GO:0120057
term: regulation of small intestinal transit
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of any small intestinal transit process, the migration of ingested material along the length of the small intestine.


go_id: GO:0120058
term: positive regulation of small intestinal transit
ontology: BP
definition:
Any process that increases the frequency, rate or extent of any small intestinal transit process, the migration of ingested material along the length of the small intestine.


go_id: GO:0120059
term: negative regulation of small intestinal transit
ontology: BP
definition:
Any process that decreases the frequency, rate or extent of any small intestinal transit process, the migration of ingested material along the length of the small intestine.


go_id: GO:0120060
term: regulation of gastric emptying
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of any gastric emptying process, the process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum.


go_id: GO:0120061
term: negative regulation of gastric emptying
ontology: BP
definition:
Any process that decreases the frequency, rate or extent of any gastric emptying process, the process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum.


go_id: GO:0120062
term: positive regulation of gastric emptying
ontology: BP
definition:
Any process that increases the frequency, rate or extent of any gastric emptying process, the process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum.


go_id: GO:0120063
term: stomach smooth muscle contraction
ontology: BP
definition:
A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs throughout the length of the stomach.


go_id: GO:0120064
term: stomach pylorus smooth muscle contraction
ontology: BP
definition:
A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the most distal part of the stomach.


go_id: GO:0120065
term: pyloric antrum smooth muscle contraction
ontology: BP
definition:
A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the widest part of the pylorus that is continuous with the body of the stomach.


go_id: GO:0120066
term: pyloric canal smooth muscle contraction
ontology: BP
definition:
A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the distal part of the pylorus between the pyloric antrum and the pyloric sphincter.


go_id: GO:0120067
term: pyloric sphincter smooth muscle contraction
ontology: BP
definition:
A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the narrowest part of the pylorus that separates the stomach from the duodenum.


go_id: GO:0120068
term: regulation of stomach fundus smooth muscle contraction
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of any stomach fundus smooth muscle contraction.


go_id: GO:0120069
term: positive regulation of stomach fundus smooth muscle contraction
ontology: BP
definition:
Any process that increases the frequency, rate or extent of any stomach fundus smooth muscle contraction.


go_id: GO:0120070
term: negative regulation of stomach fundus smooth muscle contraction
ontology: BP
definition:
Any process that decreases the frequency, rate or extent of any stomach fundus smooth muscle contraction.


go_id: GO:0120071
term: regulation of pyloric antrum smooth muscle contraction
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of any pyloric antrum smooth muscle contraction.


go_id: GO:0120072
term: positive regulation of pyloric antrum smooth muscle contraction
ontology: BP
definition:
Any process that increases the frequency, rate or extent of any pyloric antrum smooth muscle contraction.


go_id: GO:0120073
term: negative regulation of pyloric antrum smooth muscle contraction
ontology: BP
definition:
Any process that decreases the frequency, rate or extent of any pyloric antrum smooth muscle contraction.


go_id: GO:0120074
term: regulation of endocardial cushion cell differentiation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of cell differentiation, the process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cushion cell.


go_id: GO:0120075
term: positive regulation of endocardial cushion cell differentiation
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of endocardial cushion cell differentiation.


go_id: GO:0120076
term: negative regulation of endocardial cushion cell differentiation
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of endocardial cushion cell differentiation.


go_id: GO:0120077
term: angiogenic sprout fusion
ontology: BP
definition:
The connection of an angiogenic sprout to another vessel or sprout during the formation of vascular networks by sprouting angiogenesis.


go_id: GO:0120078
term: cell adhesion involved in sprouting angiogenesis
ontology: BP
definition:
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the formation of a blood vessel network.


go_id: GO:0120082
term: smooth endoplasmic reticulum cisterna
ontology: CC
definition:
A subcompartment of the smooth endoplasmic reticulum consisting of lumenal expansion into a flattened, disc-shaped cavity.


go_id: GO:0120083
term: rough endoplasmic reticulum cisterna
ontology: CC
definition:
A subcompartment of the rough endoplasmic reticulum consisting of lumenal expansion into a flattened, disc-shaped cavity.


go_id: GO:0120084
term: endothelial tip cell filopodium assembly
ontology: BP
definition:
The assembly of a filopodium, a thin, stiff protrusion extended by the endothelial tip cell of a vascular sprout.


go_id: GO:0120086
term: (3S)-(+)-asterisca-2(9),6-diene synthase activity
ontology: MF
definition:
Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + (3S)-(+)-asterisca-2(9),6-diene.


go_id: GO:0120093
term: regulation of peptidyl-lysine crotonylation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of crotonylation of a lysine residue in a protein.


go_id: GO:0120095
term: vacuole-isolation membrane contact site
ontology: CC
definition:
An organelle membrane contact site formed at the junction of the vacuolar membrane and the isolation membrane or phagophore in response to starvation or other stresses, leading to the formation of the autophagosome.


go_id: GO:0120097
term: glycosylphosphatidylinositol-mannosyltransferase II complex
ontology: CC
definition:
A protein complex that is involved in the transfer of the second mannose to the glycosylphosphatidylinositol (GPI) during GPI precursor assembly. In yeast S. cerevisiae this complex consists of GPI18p and PGA1p.


go_id: GO:0120098
term: procentriole
ontology: CC
definition:
A cellular structure that is the site of a developing centriole, which will become a microtubule organizing center. During the canonical pathway of centriole duplication that occurs during the cell division cycle, procentrioles grow at the proximal ends of both mother and daughter centrioles. In the newly divided cells, the original mother and daughter centrioles become mother centrioles while the procentrioles become the new daughter centrioles. Procentrioles can also arise from de novo pathways that occur in multiciliated cells. In ciliated epithelial cells, numerous procentrioles arise form electron dense material referred to as fibrous granules and deuterosomes. The pathway of procentriole formation in multiciliated protists appears to be similar to that in mammalian multiciliated epithelium. In sperm of primative land plants, multiple procentrioles are formed from a blepharoplast giving rise to multicilated sperm cells.


go_id: GO:0120099
term: procentriole replication complex
ontology: CC
definition:
A protein complex that acts as a chaperone or scaffold for centriolar proteins during the maturation of the procentriole. Some of its members may become integrated into the growing centriole. Examples are the CPAP(CENPJ)-STIL complex, CEP192-PLK4 complex or CEP152-PLK4 complex in vertebrates.


go_id: GO:0120100
term: bacterial-type flagellum motor
ontology: CC
definition:
A transmembrane complex embedded in the cytoplasmic membrane which is the motor force, or torque, generator of the bacterial-type flagellum. The motor consists of a membrane-anchored rotor complex surrounded by one or more stator complexes in the cytoplasmic membrane. The stator consists of a hetero-hexameric complex of 2 membrane proteins, A and B, with stoichiometry A4B2. Examples are the H+ driven MotA-MotB stator complex of Escherichia coli and Salmonella enterica, and the Na+ driven PomA-PomB stator complex of Vibrio and Shewanella species. The rotor complex consists of a membrane-anchored ring and the motor switch complex, which controls the direction of flagellar rotation.


go_id: GO:0120101
term: bacterial-type flagellum stator complex
ontology: CC
definition:
A hetero-hexameric complex of 2 membrane proteins, A and B, with stoichiometry A4B2. The A and B proteins form a channel through which flow the ions that power the bacterial-type flagellum. They form the stator, or nonrotating portion, of the flagellum motor with the B protein apparently attached to the peptidoglycan cell wall. Examples include the H+ driven MotA-MotB stator complex of Escherichia coli and Salmonella enterica, and the Na+ driven PomA-PomB stator complex of Vibrio and Shewanella species.


go_id: GO:0120102
term: bacterial-type flagellum secretion apparatus
ontology: CC
definition:
A part of the bacterial-type flagellum that is located at the cytoplasmic side of the MS ring and composed of six membrane proteins (FlhA, FlhB, FliP, FliQ, FliR, and FliO, or orthologs thereof) and three soluble proteins (FliI, FliH, and FliJ, or orthologs thereof) in the cytoplasm. It is responsible for secretion of flagellar type III protein substrates, including the proteins of the flagellar rod, hook, and filament.


go_id: GO:0120103
term: centriolar subdistal appendage
ontology: CC
definition:
A protein complex which assembles on the mother centriole during cilium formation, adjacent and proximal to a centriolar distal appendage. In human, it contains ODF2, CNTRL, NIN, CCDC120c and CCDC68.


go_id: GO:0120104
term: mitotic actomyosin contractile ring, proximal layer
ontology: CC
definition:
The region of the mitotic actomyosin ring adjacent to the plasma membrane where membrane bound scaffolds are located.


go_id: GO:0120105
term: mitotic actomyosin contractile ring, intermediate layer
ontology: CC
definition:
The region of the mitotic actomyosin ring in between the proximal layer and the actin filament layer. This region contains the accessory protein network, some actin filaments and connections between the proximal layer and the actin filament layer.


go_id: GO:0120106
term: mitotic actomyosin contractile ring, distal actin filament layer
ontology: CC
definition:
The region of the mitotic actomyosin ring containing actin filaments and cross linkers, myosin motors, and connections to the plasma membrane through the intermediate layer. It is further from the plasma membrane than the intermediate layer which it is adjacent to.


go_id: GO:0120107
term: bacterial-type flagellum rotor complex
ontology: CC
definition:
The rotor complex of the bacterial-type flagellum consists of a membrane-anchored ring and the motor switch complex, which participates in the conversion of proton/Na+ energy into the mechanical work of rotation and controls the direction of flagellar rotation.


go_id: GO:0120109
term: mitotic telomere clustering and tethering at nuclear periphery
ontology: BP
definition:
The process in which the telomeres are gathered together to a small number of foci per chromosome (usually one per chromosome or fewer), and moved to and tethered at the nuclear periphery, as part of a mitotic cell cycle.


go_id: GO:0120110
term: interphase mitotic telomere clustering
ontology: BP
definition:
The process whereby the mitotic telomeres are gathered together during, or prior to, attachment to the nuclear envelope.


go_id: GO:0120111
term: neuron projection cytoplasm
ontology: CC
definition:
All of the contents of a plasma membrane bounded neuron projection, excluding the plasma membrane surrounding the projection.


go_id: GO:0120113
term: cytoplasm to vacuole transport by the NVT pathway
ontology: BP
definition:
A pathway targeting soluble cytosolic proteins to the vacuole lumen. It uses a selective autophagy receptor protein Nbr1, which is an ortholog of mammalian NBR1, and is remotely related to S. cerevisiae Cvt pathway receptor protein Atg19. Similar to the Cvt pathway, the cargos transported by this pathway are hydrolases, which presumably contribute to the hydrolytic activities in the vacuole lumen. Different from the Cvt pathway, this pathway does not require the macroautophagy machinery, but instead relies on the ESCRT machinery for cargo sequestration. This pathway is observed in the fission yeast S. pombe.


go_id: GO:0120114
term: Sm-like protein family complex
ontology: CC
definition:
A protein complex containing members of the Like-Sm family of proteins, which includes both the Sm proteins and the Lsm proteins, and which generally form hexameric or heptameric ring structures which bind to RNA. While some of these ring complexes may form independently of RNA, many only form in association with their target RNA. In addition to Lsm-family proteins, many of these complexes contain additional protein members. Members of this family of complexes include the snRNPs which comprise the majority of the spliceosome. Others are involved in the 5' to 3' degradation pathways of mRNAs in the cytoplasm and of unspliced transcripts in the nucleus, as well as other diverse roles.


go_id: GO:0120115
term: Lsm2-8 complex
ontology: CC
definition:
A heteroheptameric, nuclear protein complex composed of Lsm2, Lsm3, Lsm4, Lsm5, Lsm6, Lsm7, and Lsm8, or orthologs thereof, that selectively binds to snRNAs, in particular U6 or U6atac snRNAs, and also to unspliced transcripts localized within the nucleus.


go_id: GO:0120117
term: T cell meandering migration
ontology: BP
definition:
The random-like motility observed for T cells in lymph nodes which enhances surveillance of antigens presented by major histocompatibility complex (MHC) molecules on antigen presenting cells (APCs).


go_id: GO:0120118
term: flagella connector
ontology: CC
definition:
A mobile transmembrane junction at the tip of the flagellum of some kinetoplastid species linking the tip of a new growing flagellum to an older flagellum.


go_id: GO:0120119
term: flagellum attachment zone
ontology: CC
definition:
A network of cytoskeletal and membranous connections responsible for the lateral attachment of the cilium to the cell body in some trypanosomatid species.


go_id: GO:0120120
term: bilobe structure
ontology: CC
definition:
A cytoskeletal structure in some kinetoplastid species linking the structures of the ciliary pocket collar and the flagellum attachment zone (aka cilium attachment zone).


go_id: GO:0120121
term: tripartite attachment complex
ontology: CC
definition:
A three-part cytoskeletal structure in kinetoplastid species linking mitochondrial DNA organised in a kinetoplast through the mitochondrial membranes to the basal body.


go_id: GO:0120122
term: prolactin metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving prolactin, a protein hormone of the anterior pituitary gland that promotes lactation in response to the suckling stimulus of hungry young mammals.


go_id: GO:0120123
term: ubiquitin activating enzyme complex
ontology: CC
definition:
A protein complex responsible for the catalysis of the reaction: E1 + ubiquitin + ATP--> E1-ubiquitin + AMP + PPi, where the E1-ubiquitin linkage is a thioester bond between the C-terminal glycine of Ub and a sulfhydryl side group of an E1 cysteine residue. This is the first step in a cascade of reactions in which ubiquitin is ultimately added to a protein substrate.


go_id: GO:0120124
term: membrane fusion priming complex
ontology: CC
definition:
A protein complex that primes vacuolar or vesicular membranes for fusion with other intracellular membranes, by promoting the dissociation of cis-SNARE complexes.


go_id: GO:0120125
term: PNGase complex
ontology: CC
definition:
A protein complex responsible for the catalysis of the reaction: 4-N-(N-acetyl-D-glucosaminyl)-protein + H2O = N-acetyl-beta-D-glucosaminylamine + peptide L-aspartate. This reaction is the hydrolysis of an N4-(acetyl-beta-D-glucosaminyl)asparagine residue in which the N-acetyl-D-glucosamine residue may be further glycosylated, to yield a (substituted) N-acetyl-beta-D-glucosaminylamine and the peptide containing an aspartic residue.


go_id: GO:0120126
term: response to copper ion starvation
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of copper ion.


go_id: GO:0120127
term: response to zinc ion starvation
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of zinc ion.


go_id: GO:0120132
term: positive regulation of apoptotic process in bone marrow cell
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process in the bone marrow.


go_id: GO:0120133
term: negative regulation of actin cortical patch assembly
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of actin cortical patches.


go_id: GO:0120137
term: positive regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity
ontology: BP
definition:
Any process that activates or increases the frequency or rate of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity.


go_id: GO:0120138
term: regulation of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity.


go_id: GO:0120139
term: positive regulation of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity.


go_id: GO:0120140
term: negative regulation of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
ontology: BP
definition:
Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity.


go_id: GO:0120141
term: regulation of ecdysone receptor-mediated signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the activity of any ecdysone receptor-mediated signaling pathway.


go_id: GO:0120142
term: positive regulation of ecdysone receptor-mediated signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of any ecdysone receptor-mediated signaling pathway.


go_id: GO:0120143
term: negative regulation of ecdysone receptor-mediated signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of any ecdysone receptor-mediated signaling pathway.


go_id: GO:0120145
term: protein localization to basal ectoplasmic specialization
ontology: BP
definition:
A process in which a protein is transported to, or maintained in, a location within a basal ectoplasmic specialization.


go_id: GO:0120146
term: sulfatide binding
ontology: MF
definition:
Binding to sulfatide, also known as 3-O-sulfogalactosylceramide, SM4, or sulfated galactocerebroside. Sulfatide is a class of sulfoglycolipid, which are glycolipids that contain a sulfate group.


go_id: GO:0120147
term: Formylglycine-generating oxidase activity
ontology: MF
definition:
Catalysis of the reaction: A [sulfatase]-L-cysteine + O(2) + 2 a thiol = a [sulfatase]-3-oxo-L-alanine + hydrogen sulfide + a disulfide + H(2)O.


go_id: GO:0120148
term: host cell centrosome
ontology: CC
definition:
A structure in a host cell comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.


go_id: GO:0120149
term: host cell peroxisome
ontology: CC
definition:
A small host cell organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.


go_id: GO:0120150
term: regulation of mitotic actomyosin contractile ring disassembly
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring disassembly.


go_id: GO:0120151
term: positive regulation of mitotic actomyosin contractile ring disassembly
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of mitotic actomyosin contractile ring disassembly.


go_id: GO:0120154
term: negative regulation of ERBB4 signaling pathway
ontology: BP
definition:
Any process that stops, prevents or reduces the frequency, rate or extent of ERBB4 signaling pathway.


go_id: GO:0120155
term: MIH complex
ontology: CC
definition:
A trimeric complex involved in cytokinesis. Proposed to bridge actomyosin ring contraction and septum synthesis in yeast, resulting in the coordination of these processes, and leading to plasma membrane ingression and fusion. In the yeast Saccharomyces cerevisiae this complex consists of Mlc1p, Iqg1p and Hof1p proteins.


go_id: GO:0120157
term: PAR polarity complex
ontology: CC
definition:
A protein kinase complex that is required for the establishment of a cell polarity axis during the cell division cycle. Binds directly to activated CDC42 GTPase and is required for orchestrating a cellular gradient of CDC42. In S. cerevisiae components are: BEM1, CDC24 and CLA4; from worms to vertebrates it contains a PAR6 protein, PAR3 protein and an atypical PKC.


go_id: GO:0120172
ontology: BP
term:
positive regulation of actin filament bundle convergence involved in mitotic contractile ring assembly


go_id: GO:0140192
ontology: BP
term:
regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process


go_id: GO:0140193
ontology: BP
term:
regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process


go_id: GO:0140194
ontology: BP
term:
negative regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process


go_id: GO:0140195
ontology: BP
term:
positive regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process


go_id: GO:0140196
ontology: BP
term:
positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process


go_id: GO:0140199
ontology: BP
term:
negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process


go_id: GO:0140200
ontology: BP
term:
adenylate cyclase-activating adrenergic receptor signaling pathway involved in regulation of heart rate


go_id: GO:0140232
ontology: MF
term:
intracellular cAMP-activated cation channel activity involved in regulation of presynaptic membrane potential


go_id: GO:0140233
ontology: MF
term:
intracellular cAMP-activated cation channel activity involved in regulation of postsynaptic membrane potential


go_id: GO:0150047
ontology: MF
term:
G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential


go_id: GO:1900018
ontology: BP
term:
phosphorylation of RNA polymerase II C-terminal domain serine 5 residues involved in recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex


go_id: GO:1900175
ontology: BP
term:
regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry


go_id: GO:1900176
ontology: BP
term:
negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry


go_id: GO:1900224
ontology: BP
term:
positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry


go_id: GO:1900238
ontology: BP
term:
regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway


go_id: GO:1900432
ontology: BP
term:
negative regulation of filamentous growth of a population of unicellular organisms in response to heat


go_id: GO:1900433
ontology: BP
term:
positive regulation of filamentous growth of a population of unicellular organisms in response to heat


go_id: GO:1900436
ontology: BP
term:
positive regulation of filamentous growth of a population of unicellular organisms in response to starvation


go_id: GO:1900437
ontology: BP
term:
regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus


go_id: GO:1900438
ontology: BP
term:
negative regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus


go_id: GO:1900439
ontology: BP
term:
positive regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus


go_id: GO:1900441
ontology: BP
term:
negative regulation of filamentous growth of a population of unicellular organisms in response to neutral pH


go_id: GO:1900442
ontology: BP
term:
positive regulation of filamentous growth of a population of unicellular organisms in response to neutral pH


go_id: GO:1900443
ontology: BP
term:
regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus


go_id: GO:1900444
ontology: BP
term:
negative regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus


go_id: GO:1900445
ontology: BP
term:
positive regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus


go_id: GO:1900461
ontology: BP
term:
positive regulation of pseudohyphal growth by positive regulation of transcription from RNA polymerase II promoter


go_id: GO:1900463
ontology: BP
term:
negative regulation of cellular response to alkaline pH by negative regulation of transcription from RNA polymerase II promoter


go_id: GO:1900464
ontology: BP
term:
negative regulation of cellular hyperosmotic salinity response by negative regulation of transcription from RNA polymerase II promoter


go_id: GO:1900477
ontology: BP
term:
negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter


go_id: GO:1900740
ontology: BP
term:
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway


go_id: GO:1900742
ontology: BP
term:
negative regulation of filamentous growth of a population of unicellular organisms in response to pH


go_id: GO:1900743
ontology: BP
term:
positive regulation of filamentous growth of a population of unicellular organisms in response to pH


go_id: GO:1901029
ontology: BP
term:
negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway


go_id: GO:1901030
ontology: BP
term:
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway


go_id: GO:1901044
ontology: BP
term:
protein polyubiquitination involved in nucleus-associated proteasomal ubiquitin-dependent protein catabolic process


go_id: GO:1901048
ontology: BP
term:
transforming growth factor beta receptor signaling pathway involved in regulation of multicellular organism growth


go_id: GO:1901198
ontology: BP
term:
positive regulation of calcium ion transport into cytosol involved in cellular response to calcium ion


go_id: GO:1901199
ontology: BP
term:
positive regulation of calcium ion transport into cytosol involved in cellular response to salt stress


go_id: GO:1901200
ontology: BP
term:
negative regulation of calcium ion transport into cytosol involved in cellular response to salt stress


go_id: GO:1901296
ontology: BP
term:
negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment


go_id: GO:1901297
ontology: BP
term:
positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment


go_id: GO:1901346
ontology: BP
term:
negative regulation of vasculature development involved in avascular cornea development in camera-type eye


go_id: GO:1901522
ontology: BP
term:
positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus


go_id: GO:1901621
ontology: BP
term:
negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning


go_id: GO:1901622
ontology: BP
term:
positive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning


go_id: GO:1901667
ontology: BP
term:
negative regulation of skeletal muscle satellite cell activation involved in skeletal muscle regeneration


go_id: GO:1901921
ontology: BP
term:
phosphorylation of RNA polymerase II C-terminal domain involved in recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex


go_id: GO:1902097
ontology: BP
term:
positive regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium


go_id: GO:1902162
ontology: BP
term:
regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator


go_id: GO:1902163
ontology: BP
term:
negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator


go_id: GO:1902164
ontology: BP
term:
positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator


go_id: GO:1902166
ontology: BP
term:
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator


go_id: GO:1902167
ontology: BP
term:
positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator


go_id: GO:1902238
ontology: BP
term:
regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator


go_id: GO:1902239
ontology: BP
term:
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator


go_id: GO:1902240
ontology: BP
term:
positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator


go_id: GO:1902282
ontology: MF
term:
voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization


go_id: GO:1902575
ontology: BP
term:
protein localization to cell division site involved in cytokinesis, actomyosin contractile ring assembly


go_id: GO:1902772
ontology: BP
term:
positive regulation of phosphorelay signal transduction system involved in hydrogen peroxide mediated signaling pathway


go_id: GO:1902812
ontology: BP
term:
regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry


go_id: GO:1902813
ontology: BP
term:
negative regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry


go_id: GO:1902814
ontology: BP
term:
positive regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry


go_id: GO:1902844
ontology: BP
term:
positive regulation of spinal cord association neuron differentiation by negative regulation of canonical Wnt signaling pathway


go_id: GO:1902901
ontology: BP
term:
positive regulation of transcription from RNA polymerase II promoter involved in stress response to cadmium ion


go_id: GO:1902959
ontology: BP
term:
regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process


go_id: GO:1902960
ontology: BP
term:
negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process


go_id: GO:1902961
ontology: BP
term:
positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process


go_id: GO:1902963
ontology: BP
term:
negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process


go_id: GO:1902964
ontology: BP
term:
positive regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process


go_id: GO:1903022
ontology: BP
term:
positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands


go_id: GO:1903117
ontology: BP
term:
regulation of actin filament organization involved in cytokinetic actomyosin contractile ring assembly


go_id: GO:1903382
ontology: BP
term:
negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway


go_id: GO:1903481
ontology: BP
term:
negative regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly


go_id: GO:1903482
ontology: BP
term:
positive regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly


go_id: GO:1903505
ontology: BP
term:
regulation of establishment of actomyosin contractile ring localization involved in mitotic cell cycle


go_id: GO:1903554
ontology: BP
term:
G protein-coupled receptor signaling pathway involved in defense response to Gram-negative bacterium


go_id: GO:1903588
ontology: BP
term:
negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis


go_id: GO:1903589
ontology: BP
term:
positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis


go_id: GO:1903654
ontology: BP
term:
phosphorylation of RNA polymerase II C-terminal domain serine 5 residues involved in positive regulation of transcription elongation from RNA polymerase II promoter


go_id: GO:1903655
ontology: BP
term:
phosphorylation of RNA polymerase II C-terminal domain serine 2 residues involved in positive regulation of transcription elongation from RNA polymerase II promoter


go_id: GO:1903760
ontology: BP
term:
regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization


go_id: GO:1903761
ontology: BP
term:
negative regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization


go_id: GO:1903762
ontology: BP
term:
positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization


go_id: GO:1903952
ontology: BP
term:
regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization


go_id: GO:1903953
ontology: BP
term:
negative regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization


go_id: GO:1903954
ontology: BP
term:
positive regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization


go_id: GO:1904065
ontology: BP
term:
G protein-coupled acetylcholine receptor signaling pathway involved in positive regulation of acetylcholine secretion, neurotransmission


go_id: GO:1904081
ontology: BP
term:
positive regulation of transcription from RNA polymerase II promoter involved in neuron differentiation


go_id: GO:1904191
ontology: BP
term:
positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in meiotic nuclear division


go_id: GO:1904283
ontology: BP
term:
negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I


go_id: GO:1904284
ontology: BP
term:
positive regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I


go_id: GO:1904597
ontology: BP
term:
negative regulation of connective tissue replacement involved in inflammatory response wound healing


go_id: GO:1904598
ontology: BP
term:
positive regulation of connective tissue replacement involved in inflammatory response wound healing


go_id: GO:1905006
ontology: BP
term:
negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation


go_id: GO:1905007
ontology: BP
term:
positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation


go_id: GO:1905025
ontology: BP
term:
negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential


go_id: GO:1905026
ontology: BP
term:
positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential


go_id: GO:1905054
ontology: MF
term:
calcium-induced calcium release activity involved in regulation of presynaptic cytosolic calcium ion concentration


go_id: GO:1905055
ontology: MF
term:
calcium:cation antiporter activity involved in regulation of presynaptic cytosolic calcium ion concentration


go_id: GO:1905056
ontology: MF
term:
P-type calcium transporter activity involved in regulation of presynaptic cytosolic calcium ion concentration


go_id: GO:1905057
ontology: MF
term:
voltage-gated calcium channel activity involved in regulation of postsynaptic cytosolic calcium levels


go_id: GO:1905058
ontology: MF
term:
calcium-induced calcium release activity involved in regulation of postsynaptic cytosolic calcium ion concentration


go_id: GO:1905059
ontology: MF
term:
P-type calcium transporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration


go_id: GO:1905060
ontology: MF
term:
calcium:cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration


go_id: GO:1905090
ontology: BP
term:
negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization


go_id: GO:1905091
ontology: BP
term:
positive regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization


go_id: GO:1905261
ontology: BP
term:
regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination


go_id: GO:1905262
ontology: BP
term:
negative regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination


go_id: GO:1905263
ontology: BP
term:
positive regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination


go_id: GO:1905287
ontology: BP
term:
positive regulation of G2/M transition of mitotic cell cycle involved in cellular response to nitrogen starvation


go_id: GO:1905391
ontology: BP
term:
regulation of protein localization to cell division site involved in cell separation after cytokinesis


go_id: GO:1905741
ontology: BP
term:
calcium export from the mitochondrion involved in positive regulation of presynaptic cytosolic calcium concentration


go_id: GO:1905743
ontology: BP
term:
calcium import into the mitochondrion involved in negative regulation of presynaptic cytosolic calcium concentration


go_id: GO:1905930
ontology: BP
term:
regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching


go_id: GO:1905931
ontology: BP
term:
negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching


go_id: GO:1905932
ontology: BP
term:
positive regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching


go_id: GO:1990095
ontology: BP
term:
positive regulation of transcription from RNA polymerase II promoter in response to reactive oxygen species


go_id: GO:1990260
ontology: BP
term:
negative regulation of transcription from RNA polymerase II promoter by transcription factor localization involved in response to DNA damage checkpoint signaling


go_id: GO:1990440
ontology: BP
term:
positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress


go_id: GO:1990441
ontology: BP
term:
negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress


go_id: GO:1990669
ontology: BP
term:
endoplasmic reticulum-Golgi intermediate compartment (ERGIC) derived vesicle fusion with endoplasmic reticulum membrane


go_id: GO:1990687
ontology: BP
term:
endoplasmic reticulum-derived vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane


go_id: GO:1990689
ontology: BP
term:
endoplasmic reticulum-Golgi intermediate compartment (ERGIC) derived vesicle fusion with Golgi cis cisterna membrane


go_id: GO:2000079
ontology: BP
term:
regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation


go_id: GO:2000080
ontology: BP
term:
negative regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation


go_id: GO:2000081
ontology: BP
term:
positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation


go_id: GO:2000313
ontology: BP
term:
regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation


go_id: GO:2000314
ontology: BP
term:
negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation


go_id: GO:2000315
ontology: BP
term:
positive regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation


go_id: GO:2000526
ontology: BP
term:
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation


go_id: GO:2000701
ontology: BP
term:
glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation


go_id: GO:2000702
ontology: BP
term:
regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation


go_id: GO:2000703
ontology: BP
term:
negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation


go_id: GO:2000704
ontology: BP
term:
positive regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation


go_id: GO:2000721
ontology: BP
term:
positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation


go_id: GO:2000733
ontology: BP
term:
regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation


go_id: GO:2000734
ontology: BP
term:
negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation


go_id: GO:2000735
ontology: BP
term:
positive regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation


go_id: GO:2000763
ontology: BP
term:
positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process


go_id: GO:2000777
ontology: BP
term:
positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia


go_id: GO:2000801
ontology: BP
term:
negative regulation of endocardial cushion to mesenchymal transition involved in heart valve formation


go_id: GO:2000802
ontology: BP
term:
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation


go_id: GO:2000820
ontology: BP
term:
negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation


go_id: GO:2001188
ontology: BP
term:
regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell


go_id: GO:2001189
ontology: BP
term:
negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell


go_id: GO:2001190
ontology: BP
term:
positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell


go_id: GO:2001271
ontology: BP
term:
negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis


go_id: GO:2001272
ontology: BP
term:
positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis


# go_obsolete

go_id: GO:0000005
term: obsolete ribosomal chaperone activity
ontology: MF
definition:
OBSOLETE. Assists in the correct assembly of ribosomes or ribosomal subunits in vivo, but is not a component of the assembled ribosome when performing its normal biological function.


go_id: GO:0000008
term: obsolete thioredoxin
ontology: MF
definition:
OBSOLETE. A small disulfide-containing redox protein that serves as a general protein disulfide oxidoreductase. Interacts with a broad range of proteins by a redox mechanism, based on the reversible oxidation of 2 cysteine thiol groups to a disulfide, accompanied by the transfer of 2 electrons and 2 protons. The net result is the covalent interconversion of a disulfide and a dithiol.


go_id: GO:0000020
term: obsolete negative regulation of recombination within rDNA repeats
ontology: BP
definition:
OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of genetic recombination within the DNA of the genes coding for ribosomal RNA.


go_id: GO:0000051
term: obsolete urea cycle intermediate metabolic process
ontology: BP
definition:
OBSOLETE. The chemical reactions and pathways involving any of the intermediate compounds involved in the urea cycle, a cyclic metabolic pathway that converts waste nitrogen in the form of ammonium to urea.


go_id: GO:0000059
term: obsolete protein import into nucleus, docking
ontology: BP
definition:
OBSOLETE. A protein complex assembly process that contributes to protein import into the nucleus, and that results in the association of a cargo protein, a carrier protein such as an importin alpha/beta heterodimer, and a nucleoporin located at the periphery of the nuclear pore complex.


go_id: GO:0000060
term: obsolete protein import into nucleus, translocation
ontology: BP
definition:
OBSOLETE. A protein transport process that contributes to protein import into the nucleus, and that results in the vectorial transfer of a cargo-carrier protein complex through the nuclear pore complex from the cytoplasmic side to the nucleoplasmic side of the nuclear envelope.


go_id: GO:0000061
term: obsolete protein import into nucleus, substrate release
ontology: BP
definition:
OBSOLETE. A protein complex disassembly process that contributes to protein import into the nucleus, and that results in the dissociation of the cargo protein and the carrier (such as an importin alpha/beta heterodimer) from each other and from the nuclear pore complex.


go_id: GO:0000078
term: obsolete cytokinesis after mitosis checkpoint
ontology: BP
definition:
OBSOLETE. A mitotic cell cycle checkpoint that detects whether chromosome segregation is complete and negatively regulates cytokinesis following mitosis.


go_id: GO:0000108
term: obsolete repairosome
ontology: CC
definition:
OBSOLETE. A stable complex of proteins that carry out the DNA damage recognition and incision reactions characteristic of nucleotide excision repair (NER), such as DNA damage recognition, DNA helix unwinding, and endonucleolytic cleavage at sites flanking damaged DNA; includes TFIIH subunits and additional polypeptides; may form in the absence of DNA damage.


go_id: GO:0000114
term: obsolete regulation of transcription involved in G1 phase of mitotic cell cycle
ontology: BP
definition:
OBSOLETE. Any process that regulates transcription such that the target genes are transcribed as part of the G1 phase of the mitotic cell cycle.


go_id: GO:0000115
term: obsolete regulation of transcription involved in S phase of mitotic cell cycle
ontology: BP
definition:
OBSOLETE. A cell cycle process that regulates transcription such that the target genes are transcribed as part of the S phase of the mitotic cell cycle.


go_id: GO:0000116
term: obsolete regulation of transcription involved in G2-phase of mitotic cell cycle
ontology: BP
definition:
OBSOLETE. Any process that regulates transcription such that the target genes are transcribed as part of the G2 phase of the mitotic cell cycle.


go_id: GO:0000135
term: obsolete cytokinesis checkpoint
ontology: BP
definition:
OBSOLETE. A mitotic cell cycle checkpoint that detects a defect in cytokinesis and negatively regulates G2/M transition.


go_id: GO:0000174
term: obsolete inactivation of MAPK (mating sensu Saccharomyces)
ontology: BP
definition:
OBSOLETE. Downregulation of MAP kinase activity in the context of transduction of mating pheromone signal, as described for Saccharomyces.


go_id: GO:0000185
term: obsolete activation of MAPKKK activity
ontology: BP
definition:
OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase (MAPKKK).


go_id: GO:0000190
term: obsolete MAPKKK cascade (pseudohyphal growth)
ontology: BP
definition:
OBSOLETE. MAPKKK cascade involved in transduction of signal promoting pseudohyphal or invasive growth.


go_id: GO:0000191
term: obsolete activation of MAPKKK (pseudohyphal growth)
ontology: BP
definition:
OBSOLETE. Upregulation of MAPKKK activity in the context of regulating pseudohyphal or invasive growth.


go_id: GO:0000192
term: obsolete activation of MAPKK (pseudohyphal growth)
ontology: BP
definition:
OBSOLETE. Upregulation of a MAP kinase kinase in the context of regulating pseudohyphal or invasive growth.


go_id: GO:0000193
term: obsolete activation of MAPK (pseudohyphal growth)
ontology: BP
definition:
OBSOLETE. Upregulation of MAP kinase activity in the context of regulating pseudohyphal or invasive growth.


go_id: GO:0000194
term: obsolete inactivation of MAPK (pseudohyphal growth)
ontology: BP
definition:
OBSOLETE. Downregulation of MAP kinase activity in the context of regulating pseudohyphal or invasive growth.


go_id: GO:0000195
term: obsolete nuclear translocation of MAPK (pseudohyphal growth)
ontology: BP
definition:
OBSOLETE. Movement of a MAP kinase to the nucleus in the context of regulating pseudohyphal or invasive growth.


go_id: GO:0000197
term: obsolete activation of MAPKKK activity involved in cell wall organization or biogenesis
ontology: BP
definition:
OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase in the context of cell wall organization or biogenesis.


go_id: GO:0000198
term: obsolete activation of MAPKK activity involved in cell wall organization or biogenesis
ontology: BP
definition:
OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase kinase in the context of cell wall organization or biogenesis.


go_id: GO:0000199
term: obsolete activation of MAPK activity involved in cell wall organization or biogenesis
ontology: BP
definition:
OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase in the context of cell wall biogenesis, the assembly and arrangement of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells.


go_id: GO:0000200
term: obsolete inactivation of MAPK activity involved in cell wall organization or biogenesis
ontology: BP
definition:
OBSOLETE. Any process that terminates the activity of the active enzyme MAP kinase in the context of cell wall organization or biogenesis.


go_id: GO:0000201
term: obsolete MAPK import into nucleus involved in cell wall organization or biogenesis
ontology: BP
definition:
OBSOLETE. The directed movement of a MAP kinase to the nucleus that occurs in the context of cell wall organization or biogenesis.


go_id: GO:0000202
term: obsolete MAPKKK cascade during sporulation (sensu Saccharomyces)
ontology: BP
definition:
OBSOLETE. MAPKKK cascade involved in transduction of signal promoting sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930).


go_id: GO:0000203
term: obsolete activation of MAPKKK during sporulation (sensu Saccharomyces)
ontology: BP
definition:
OBSOLETE. Upregulation of MAPKKK activity in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930).


go_id: GO:0000204
term: obsolete activation of MAPKK during sporulation (sensu Saccharomyces)
ontology: BP
definition:
OBSOLETE. Upregulation of a MAP kinase kinase in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930).


go_id: GO:0000205
term: obsolete activation of MAPK during sporulation (sensu Saccharomyces)
ontology: BP
definition:
OBSOLETE. Upregulation of MAP kinase activity in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930).


go_id: GO:0000206
term: obsolete inactivation of MAPK during sporulation (sensu Saccharomyces)
ontology: BP
definition:
OBSOLETE. Downregulation of MAP kinase activity in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930).


go_id: GO:0000207
term: obsolete nuclear translocation of MAPK during sporulation (sensu Saccharomyces)
ontology: BP
definition:
OBSOLETE. Movement of a MAP kinase to the nucleus in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930).


go_id: GO:0000211
term: obsolete protein degradation tagging activity
ontology: MF
definition:
OBSOLETE. Covalent addition of polyubiquitin to another protein, targeting the tagged protein for destruction.


go_id: GO:0000258
term: obsolete isoleucine/valine:sodium symporter activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: (isoleucine or valine)(out) + Na+(out) = (isoleucine or valine)(in) + Na+(in).


go_id: GO:0000259
term: obsolete intracellular nucleoside transmembrane transporter activity
ontology: MF
definition:
OBSOLETE. Enables the directed movement of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose (a deoxyribonucleotide) within a cell.


go_id: GO:0000260
term: obsolete hydrogen-translocating V-type ATPase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: ATP + H2O + H(+)(in) = ADP + phosphate + H+(out). Found in vacuoles of eukaryotes and in bacteria.


go_id: GO:0000261
term: obsolete sodium-translocating V-type ATPase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: ATP + H2O + Na+(in) = ADP + phosphate + Na+(out). Found in vacuoles of eukaryotes and in bacteria.


go_id: GO:0000263
term: obsolete heterotrimeric G-protein GTPase, alpha-subunit
ontology: MF
definition:
OBSOLETE. Subunit of a heterotrimeric G-protein GTPase that contains the guanine nucleotide binding site and possesses GTPase activity.


go_id: GO:0000265
term: obsolete heterotrimeric G-protein GTPase, gamma-subunit
ontology: MF
definition:
OBSOLETE. Smallest subunit of a heterotrimeric G-protein GTPase; associates tightly with the beta subunit.


go_id: GO:0000299
term: obsolete integral to membrane of membrane fraction
ontology: CC
definition:
OBSOLETE. Integral to that fraction of cells, prepared by disruptive biochemical methods, that includes the plasma and other membranes; require detergents, such as Triton X-100, to be released from membranes.


go_id: GO:0000300
term: obsolete peripheral to membrane of membrane fraction
ontology: CC
definition:
OBSOLETE. Peripheral to that fraction of cells, prepared by disruptive biochemical methods, that includes the plasma and other membranes; can be extracted from membrane fraction with high concentrations of salt or high pH.


go_id: GO:0000362
term: obsolete first U2-type spliceosomal transesterification activity
ontology: MF
definition:
OBSOLETE. Catalysis of the first transesterification reaction of U2-type spliceosomal mRNA splicing. The intron branch site adenosine is the nucleophile attacking the 5' splice site, resulting in cleavage at this position. In cis splicing, this is the step that forms a lariat structure of the intron RNA, which is still joined to the 3' exon. The catalytic site is thought to be formed by U6 and/or U2 snRNA, and/or associated proteins.


go_id: GO:0000363
term: obsolete first U12-type spliceosomal transesterification activity
ontology: MF
definition:
OBSOLETE. Catalysis of the first transesterification reaction of U12-type spliceosomal mRNA splicing. The intron branch site adenosine is the nucleophile attacking the 5' splice site, resulting in cleavage at this position. In cis splicing, this is the step that forms a lariat structure of the intron RNA, which is still joined to the 3' exon. The catalytic site is thought to be formed by U6atac snRNA and/or U2atac snRNA, and/or associated proteins.


go_id: GO:0000364
term: obsolete second U2-type spliceosomal transesterification activity
ontology: MF
definition:
OBSOLETE. Catalysis of the second transesterification reaction of U2-type spliceosomal mRNA splicing. Ligation of the two exons occurs via a transesterification reaction where the free 3'-hydroxyl group of the 5' exon is the nucleophile attacking the 3' splice site. Non-expressed sequences are now detached from the exons. In cis splicing, the intron is in a lariat structure. The catalytic site is thought to be formed by U6 and/or U2 snRNAs and/or associated proteins.


go_id: GO:0000367
term: obsolete second U12-type spliceosomal transesterification activity
ontology: MF
definition:
OBSOLETE. Catalysis of the second transesterification reaction of U12-type spliceosomal mRNA splicing. Ligation of the two exons occurs via a transesterification reaction where the free 3'-hydroxyl group of the 5' exon is the nucleophile attacking the 3' splice site. Non-expressed sequences are now detached from the exons. In cis splicing, the intron is in a lariat structure. The catalytic site is thought to be formed by U6 and/or U2 snRNAs and/or associated proteins.


go_id: GO:0000456
term: obsolete dimethylation involved in SSU-rRNA maturation
ontology: BP
definition:
OBSOLETE. Dimethylation of the N6 amino groups of two consecutive adenosine residues near the 3'-end of the SSU rRNA. This process has been conserved from bacteria to eukaryotes.


go_id: GO:0000504
term: obsolete proteasome regulatory particle (sensu Bacteria)
ontology: CC
definition:
OBSOLETE. A multisubunit complex that recognizes and unfolds ubiquitinated proteins, and translocates them to the core complex in an ATP dependent manner. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).


go_id: GO:0000726
term: obsolete non-recombinational repair
ontology: BP
definition:
OBSOLETE. A DNA repair process in which that does not require the exchange of genetic material between the broken DNA molecule and a homologous DNA region.


go_id: GO:0000746
term: obsolete conjugation
ontology: BP
definition:
OBSOLETE. The union or introduction of genetic information from compatible mating types that results in a genetically different individual. Conjugation requires direct cellular contact between the organisms.


go_id: GO:0000757
term: obsolete signal transduction involved in regulation of conjugation with mutual genetic exchange
ontology: BP
definition:
OBSOLETE. A signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation without cellular fusion.


go_id: GO:0000759
term: obsolete cell morphogenesis involved in conjugation with mutual genetic exchange
ontology: BP
definition:
OBSOLETE. The change in form (cell shape and size) that occurs during sexual reproduction in order to facilitate direct contact between the compatible mating types in organisms that undergo conjugation without cellular fusion.


go_id: GO:0000763
term: obsolete cell morphogenesis involved in unidirectional conjugation
ontology: BP
definition:
OBSOLETE. The change in form (cell shape and size) that occurs during sexual reproduction in order to facilitate direct contact between the compatible mating types in organisms that undergo unidirectional conjugation.


go_id: GO:0000764
term: obsolete cellular morphogenesis involved in pheromone-induced unidirectional conjugation
ontology: BP
definition:
OBSOLETE. The change in form (cell shape and size) that contributes to sexual reproduction in order to facilitate direct contact between the compatible mating types in organisms that undergo pheromone-induced unidirectional conjugation.


go_id: GO:0000767
term: obsolete cell morphogenesis involved in conjugation
ontology: BP
definition:
OBSOLETE. The change in form (cell shape and size) that occurs during sexual reproduction in order to facilitate direct contact between the compatible mating types.


go_id: GO:0000771
term: obsolete agglutination involved in conjugation
ontology: BP
definition:
OBSOLETE. The aggregation or adhesion of compatible mating types via complementary cell-cell interactions prior to the formation of irreversible cellular contacts during conjugation.


go_id: GO:0000903
term: obsolete regulation of cell shape during vegetative growth phase
ontology: BP
definition:
OBSOLETE. Any process that modulates the surface configuration of a cell during the vegetative growth phase. The vegetative growth phase is the growth phase during which single celled organisms reproduce by budding or other asexual methods.


go_id: GO:0000988
term: obsolete transcription factor activity, protein binding
ontology: MF
definition:
OBSOLETE. Binding to a protein or protein complex, to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.


go_id: GO:0000989
term: obsolete transcription factor activity, transcription factor binding
ontology: MF
definition:
OBSOLETE. Binding to a specific transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.


go_id: GO:0000990
term: obsolete transcription factor activity, core RNA polymerase binding
ontology: MF
definition:
OBSOLETE. Binding to an RNA polymerase in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.


go_id: GO:0000991
term: obsolete transcription factor activity, core RNA polymerase II binding
ontology: MF
definition:
OBSOLETE. Binding to an RNA polymerase II (Pol II) complex, typically composed of twelve subunits, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.


go_id: GO:0001004
term: obsolete RNA polymerase III transcription regulator recruiting activity
ontology: MF
definition:
OBSOLETE. Initiating the assembly of the RNA polymerase III pre-initiation complex by binding to a control sequence in the intragenic region. This allows to recruit TFIIIB to the DNA at a site centered approximately 26 base pairs upstream of the start site of transcription. For tRNA genes, TFIIIC first associates with DNA, and then recruits TFIIIB. For 5S rRNA genes, TFIIIA binds to DNA first, followed by TFIIIC, which then recruits TFIIIB.


go_id: GO:0001007
term: obsolete transcription factor activity, RNA polymerase III transcription factor binding
ontology: MF
definition:
OBSOLETE. Binding to an RNA polymerase III transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.


go_id: GO:0001011
term: obsolete transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting
ontology: MF
definition:
OBSOLETE. Binding to a specific DNA sequence and recruiting RNA polymerase to the DNA in order to form the preinitiation complex (PIC).


go_id: GO:0001026
term: obsolete TFIIIB-type transcription factor activity
ontology: MF
definition:
OBSOLETE. Binding to an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, Once recruited to an RNA polymerase III promoter by one or more other transcription factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.


go_id: GO:0001027
term: obsolete RNA polymerase III type 1 promoter TFIIIB-type transcription factor activity
ontology: MF
definition:
OBSOLETE. Binding to an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III type 1 promoter by TFIIIA-type and TFIIIC-type factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.


go_id: GO:0001028
term: obsolete RNA polymerase III type 2 promoter TFIIIB-type transcription factor activity
ontology: MF
definition:
OBSOLETE. Binding to an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III type 2 promoter by a TFIIIC-type factor, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.


go_id: GO:0001029
term: obsolete RNA polymerase III type 3 promoter TFIIIB-type transcription factor activity
ontology: MF
definition:
OBSOLETE. Binding to an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III type 3 promoter by SNAP-type and TFIIIC-type factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.


go_id: GO:0001040
term: obsolete RNA polymerase III hybrid type promoter TFIIIB-type transcription factor activity
ontology: MF
definition:
OBSOLETE. Binding to an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III hybrid type promoter, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.


go_id: GO:0001061
term: obsolete bacterial-type RNA polymerase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a bacterial-type specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.


go_id: GO:0001062
term: obsolete plastid PEP-A RNA polymerase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a plastid PEP-A RNA polymerase II specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.


go_id: GO:0001063
term: obsolete plastid PEP-B RNA polymerase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a plastid PEP-B RNA polymerase II specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.


go_id: GO:0001074
ontology: MF
term:
obsolete transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding involved in preinitiation complex assembly

definition:
OBSOLETE. Binding to a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to promote assembly of the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription from an RNA polymerase II promoter.


go_id: GO:0001076
term: obsolete transcription factor activity, RNA polymerase II transcription factor binding
ontology: MF
definition:
OBSOLETE. Binding to an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.


go_id: GO:0001082
term: obsolete transcription factor activity, RNA polymerase I transcription factor binding
ontology: MF
definition:
OBSOLETE. Binding to an RNA polymerase I transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.


go_id: GO:0001083
term: obsolete transcription factor activity, RNA polymerase II basal transcription factor binding
ontology: MF
definition:
OBSOLETE. Binding to a basal RNA polymerase II transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.


go_id: GO:0001084
term: obsolete transcription factor activity, TFIID-class binding
ontology: MF
definition:
OBSOLETE. Binding to a basal RNA polymerase II transcription factor of the TFIID class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well.


go_id: GO:0001086
term: obsolete transcription factor activity, TFIIA-class binding
ontology: MF
definition:
OBSOLETE. Binding to a basal RNA polymerase II transcription factor of the TFIIA class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well.


go_id: GO:0001087
term: obsolete transcription factor activity, TFIIB-class binding
ontology: MF
definition:
OBSOLETE. Binding to a basal RNA polymerase II transcription factor of the TFIIB class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well.


go_id: GO:0001088
term: obsolete transcription factor activity, TFIIE-class binding
ontology: MF
definition:
OBSOLETE. Binding to a basal RNA polymerase II transcription factor of the TFIIE class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well.


go_id: GO:0001089
term: obsolete transcription factor activity, TFIIF-class transcription factor binding
ontology: MF
definition:
OBSOLETE. Binding to a basal RNA polymerase II transcription factor of the TFIIF class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well.


go_id: GO:0001090
term: obsolete transcription factor activity, TFIIH-class binding
ontology: MF
definition:
OBSOLETE. Binding to a basal RNA polymerase II transcription factor of the TFIIH class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well.


go_id: GO:0001128
ontology: MF
term:
obsolete RNA polymerase II transcription coactivator activity involved in preinitiation complex assembly

definition:
OBSOLETE. Binding to an RNA polymerase II (RNAP II) regulatory transcription factor and also with the RNAP II basal transcription machinery in order to increase the frequency, rate or stability of the aggregation, arrangement and bonding together of proteins on RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC). Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between activating transcription factors and the basal RNAP II transcription machinery.


go_id: GO:0001129
ontology: MF
term:
obsolete RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly

definition:
OBSOLETE. Binding to a member of the class of TATA-binding proteins (TBP), including any of the TBP-related factors (TRFs), to facilitate the aggregation, arrangement and bonding together of proteins on RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase.


go_id: GO:0001132
term: obsolete RNA polymerase II transcription factor activity, TBP-class protein binding
ontology: MF
definition:
OBSOLETE. Binding to a member of the class of TATA-binding proteins (TBP), including any of the TBP-related factors (TRFs), in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well.


go_id: GO:0001134
term: obsolete transcription regulator recruiting activity
ontology: MF
definition:
OBSOLETE. The function of binding to an RNA polymerase (RNAP) transcription regulator and recruiting it to the general transcription machinery complex in order to modulate transcription initiation.


go_id: GO:0001135
term: obsolete RNA polymerase II transcription regulator recruiting activity
ontology: MF
definition:
OBSOLETE. The function of binding to an RNA polymerase II (RNAP II) transcription regulator and recruiting it to the general transcription machinery complex in order to modulate transcription initiation.


go_id: GO:0001149
ontology: MF
term:
obsolete transcription factor activity, bacterial-type RNA polymerase termination site sequence-specific binding

definition:
OBSOLETE. Binding to a sequence of DNA that is a termination site for bacterial-type RNA polymerase in order to promote transcription termination by bacterial-type RNA polymerase.


go_id: GO:0001152
ontology: MF
term:
obsolete transcription factor activity, RNA polymerase III type 1 promoter sequence-specific binding, TFIIIC recruiting

definition:
OBSOLETE. The function of binding to a specific DNA sequence motif in a type 1 RNA polymerase III (Pol III) promoter in order to recruit the transcription factor TFIIIC to the promoter.


go_id: GO:0001153
term: obsolete transcription factor activity, RNA polymerase III transcription factor recruiting
ontology: MF
definition:
OBSOLETE. The function of binding to an RNA polymerase III (RNAP III) transcription factor and recruiting it to the transcription machinery complex in order to modulate transcription by RNAP III.


go_id: GO:0001167
term: obsolete RNA polymerase I transcription factor activity, sequence-specific DNA binding
ontology: MF
definition:
OBSOLETE. Binding to a specific DNA sequence in order to modulate transcription by RNA polymerase I. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.


go_id: GO:0001168
ontology: MF
term:
obsolete transcription factor activity, RNA polymerase I upstream control element sequence-specific binding

definition:
OBSOLETE. Binding to a upstream control element (UCE, or alternately referred to as the upstream element, UE), a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase I in order to modulate transcription by RNA polymerase I.


go_id: GO:0001169
term: obsolete transcription factor activity, RNA polymerase I CORE element sequence-specific binding
ontology: MF
definition:
OBSOLETE. Binding to CORE element, a regulatory region composed of the transcription start site and binding sites for transcription factors of the RNA polymerase I transcription machinery in order to modulate transcription by RNA polymerase I.


go_id: GO:0001170
term: obsolete transcription factor activity, RNA polymerase I enhancer sequence-specific binding
ontology: MF
definition:
OBSOLETE. Binding to a RNA polymerase I (Pol I) enhancer in order to modulate transcription by RNA polymerase I.


go_id: GO:0001186
term: obsolete RNA polymerase I transcription regulator recruiting activity
ontology: MF
definition:
OBSOLETE. The function of binding to an RNA polymerase I (RNAP I) transcription regulator and recruiting it to the general transcription machinery complex in order to modulate transcription initiation.


go_id: GO:0001190
term: obsolete transcriptional activator activity, RNA polymerase II transcription factor binding
ontology: MF
definition:
OBSOLETE. Binding to an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to increase the frequency, rate or extent of transcription from an RNA polymerase II promoter. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.


go_id: GO:0001191
term: obsolete transcriptional repressor activity, RNA polymerase II transcription factor binding
ontology: MF
definition:
OBSOLETE. Binding to an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.


go_id: GO:0001196
term: obsolete regulation of mating-type specific transcription from RNA polymerase II promoter
ontology: BP
definition:
OBSOLETE. Any mating-type specific process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.


go_id: GO:0001197
term: obsolete positive regulation of mating-type specific transcription from RNA polymerase II promoter
ontology: BP
definition:
OBSOLETE. Any mating-type specific process that activates or increases the rate of transcription from an RNA polymerase II promoter.


go_id: GO:0001198
term: obsolete negative regulation of mating-type specific transcription from RNA polymerase II promoter
ontology: BP
definition:
OBSOLETE. Any mating-type specific process that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter.


go_id: GO:0001300
term: obsolete chronological cell aging
ontology: BP
definition:
OBSOLETE. The process associated with progression of the cell from its inception to the end of its lifespan that occurs when the cell is in a non-dividing, or quiescent, state.


go_id: GO:0001301
term: obsolete progressive alteration of chromatin involved in cell aging
ontology: BP
definition:
OBSOLETE. Any chromatin organization process that occurs during the lifespan of the cell that results in changes in chromatin structure. Such changes may lead to gene dysregulation and ultimately to a loss in cell homeostasis, bringing about an aging phenotype.


go_id: GO:0001302
term: obsolete replicative cell aging
ontology: BP
definition:
OBSOLETE. The process associated with progression of the cell from its inception to the end of its lifespan that occurs as the cell continues cycles of growth and division.


go_id: GO:0001303
term: obsolete nucleolar fragmentation involved in replicative aging
ontology: BP
definition:
OBSOLETE. A nucleolar fragmentation process that gives rise to multiple rounded structures and that occurs in conjunction with increasing age in dividing cells.


go_id: GO:0001304
term: obsolete progressive alteration of chromatin involved in replicative cell aging
ontology: BP
definition:
OBSOLETE. A process that results in changes in chromatin structure contributing to replicative cell aging.


go_id: GO:0001305
term: obsolete progressive alteration of chromatin involved in chronological cell aging
ontology: BP
definition:
OBSOLETE. A process that results in changes in chromatin structure contributing to chronological cell aging, occurring in non-dividing cells.


go_id: GO:0001306
term: obsolete age-dependent response to oxidative stress
ontology: BP
definition:
OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, where the change varies according to the age of the cell or organism.


go_id: GO:0001307
term: obsolete extrachromosomal circular DNA accumulation involved in replicative cell aging
ontology: BP
definition:
OBSOLETE. Increase in abundance of circular DNA molecules in dividing cells as they age. These molecules originate in the chromosome but are excised and circularized, often by intramolecular homologous recombination between direct tandem repeats, and then replicated independently of chromosomal replication.


go_id: GO:0001308
term: obsolete negative regulation of chromatin silencing involved in replicative cell aging
ontology: BP
definition:
OBSOLETE. The process, which occurs as a dividing cell ages, leading to expression of genes that are typically not expressed due to silencing by regulatory proteins.


go_id: GO:0001309
term: obsolete age-dependent telomere shortening
ontology: BP
definition:
OBSOLETE. Progressive reduction in length of the telomeres, the termini of eukaryotic chromosomes, that occurs as part of the cellular aging process.


go_id: GO:0001310
term: obsolete extrachromosomal rDNA circle accumulation involved in replicative cell aging
ontology: BP
definition:
OBSOLETE. Increase in abundance of circular DNA molecules containing ribosomal DNA repeats in dividing cells as they age. These molecules originate in the chromosome but are excised and circularized, often by intramolecular homologous recombination between direct tandem repeats, and then replicated independently of chromosomal replication.


go_id: GO:0001311
ontology: BP
term:
obsolete formation of extrachromosomal circular rDNA by homologous recombination involved in replicative cell aging

definition:
OBSOLETE. Excision from the chromosome and circularization of DNA molecules encoding ribosomal RNA in dividing cells as they age.


go_id: GO:0001312
term: obsolete replication of extrachromosomal rDNA circles involved in replicative cell aging
ontology: BP
definition:
OBSOLETE. Replication of rDNA following its excision from the chromosome of dividing cells as they age. Extrachromosomal rDNA forms a circle that contains at least one autonomously replicating sequence (ARS), which supports replication independent of chromosomal replication.


go_id: GO:0001313
term: obsolete formation of extrachromosomal circular DNA involved in replicative cell aging
ontology: BP
definition:
OBSOLETE. Excision from the chromosome and circularization of a region of chromosomal DNA, generally, but not always, via homologous recombination between direct tandem repeats, in dividing cells as they age.


go_id: GO:0001314
term: obsolete replication of extrachromosomal circular DNA involved in replicative cell aging
ontology: BP
definition:
OBSOLETE. Replication of circular DNA following excision from the chromosome of dividing cells as they age; replication of extrachromosomal circular DNA generally occurs independently of chromosomal replication.


go_id: GO:0001315
term: obsolete age-dependent response to reactive oxygen species
ontology: BP
definition:
OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of reactive oxygen species, where the change varies according to the age of the cell or organism.


go_id: GO:0001316
term: obsolete age-dependent response to reactive oxygen species involved in replicative cell aging
ontology: BP
definition:
OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) occurring during the process of replicative cell aging as a result of reactive oxygen species, where the change varies according to the age of the cell or organism.


go_id: GO:0001317
term: obsolete accumulation of oxidatively modified proteins involved in replicative cell aging
ontology: BP
definition:
OBSOLETE. Accumulation of proteins that have undergone reactions with reactive oxygen species in aging dividing cells and exhibit modifications such as increased protein carbonyl content, oxidized methionine, protein hydrophobicity, and cross-linking.


go_id: GO:0001318
term: obsolete formation of oxidatively modified proteins involved in replicative cell aging
ontology: BP
definition:
OBSOLETE. Chemical reaction, between proteins and reactive oxygen species, that occurs in dividing cells as they age and leads to a variety of changes in the affected proteins, including increases in protein carbonyl content, oxidized methionine, protein hydrophobicity, and cross-linking.


go_id: GO:0001319
term: obsolete inheritance of oxidatively modified proteins involved in replicative cell aging
ontology: BP
definition:
OBSOLETE. A protein localization process in which progeny cells acquire, or are barred from acquiring, proteins that have been altered by reaction with reactive oxygen species in dividing aging cells.


go_id: GO:0001320
term: obsolete age-dependent response to reactive oxygen species involved in chronological cell aging
ontology: BP
definition:
OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) occurring in non-dividing cells as they age as a result of reactive oxygen species, where the change varies according to the age of the cell or organism.


go_id: GO:0001321
term: obsolete age-dependent general metabolic decline involved in replicative cell aging
ontology: BP
definition:
OBSOLETE. A process of general metabolic decline that arises in dividing cells as they age, and alters cellular metabolism to cause a decline in cell function.


go_id: GO:0001322
term: obsolete age-dependent response to oxidative stress involved in replicative cell aging
ontology: BP
definition:
OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) occurring in dividing cells as they age as a result of oxidative stress, where the change varies according to the age of the cell or organism.


go_id: GO:0001323
term: obsolete age-dependent general metabolic decline involved in chronological cell aging
ontology: BP
definition:
OBSOLETE. A process of general metabolic decline that arises in non-dividing cells as they age, and alters cellular metabolism to cause a decline in cell function.


go_id: GO:0001324
term: obsolete age-dependent response to oxidative stress involved in chronological cell aging
ontology: BP
definition:
OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) occurring in non-dividing cells as they age as a result of oxidative stress, where the change varies according to the age of the cell or organism.


go_id: GO:0001404
term: obsolete invasive growth
ontology: BP
definition:
OBSOLETE. Growth of a pathogenic organism that results in penetration into cells or tissues of the host organism. This often (but not necessarily) includes a filamentous growth form, and also can include secretion of proteases and lipases to break down host tissue.


go_id: GO:0001506
term: obsolete neurotransmitter biosynthetic process and storage
ontology: BP
definition:
OBSOLETE. The chemical reactions and pathways resulting in the formation of neurotransmitters and the storage of the synthesized molecules.


go_id: GO:0001511
term: obsolete fibrillin
ontology: MF
definition:
OBSOLETE. Large glycoprotein that is a calcium binding component of connective tissue microfibrils containing 34 six-cysteine (EGF-like) repeats and five eight-cysteine (TGFbeta-1 binding protein-like) repeats. Defects associated with Marfan syndrome.


go_id: GO:0001526
term: obsolete proteoglycan sulfate transfer
ontology: BP
definition:
OBSOLETE. Transfer of sulfate to a proteoglycan (a glycoprotein whose carbohydrate units are glycosaminoglycans) using 3'-phosphoadenyl sulfate.


go_id: GO:0001528
term: obsolete elastin
ontology: MF
definition:
OBSOLETE. A major structural protein of mammalian connective tissues; composed of one third glycine, and also rich in proline, alanine, and valine. Chains are cross-linked together via lysine residues.


go_id: GO:0001538
term: obsolete calcium-dependent cell adhesion molecule activity
ontology: MF
definition:
OBSOLETE. A calcium-dependent cell adhesion protein (type I membrane protein) that interacts in a homophilic manner in cell-cell interactions.


go_id: GO:0001557
term: obsolete metabolic process resulting in cell growth
ontology: BP
definition:
OBSOLETE. The chemical reactions that occur in living organisms that result in an increase in the mass (size) of a cell.


go_id: GO:0001559
term: obsolete regulation of cell growth by detection of nuclear:cytoplasmic ratio
ontology: BP
definition:
OBSOLETE. Any process in which the size of the nucleus with respect to the cytoplasm modulates the frequency, rate or extent of cell growth, the irreversible increase in size of a cell over time.


go_id: GO:0001584
term: obsolete rhodopsin-like receptor activity
ontology: MF
definition:
OBSOLETE. A G protein-coupled receptor that is structurally/functionally related to the rhodopsin receptor.


go_id: GO:0001619
term: obsolete lysosphingolipid and lysophosphatidic acid receptor activity
ontology: MF
definition:
OBSOLETE. Combining with lysosphingolipid or lysophosphatidic acid to initiate a change in cell activity.


go_id: GO:0001633
term: obsolete secretin-like receptor activity
ontology: MF
definition:
OBSOLETE. A G protein-coupled receptor that is structurally/functionally related to the secretin receptor.


go_id: GO:0001643
term: obsolete metabotropic glutamate, GABA-B-like receptor activity
ontology: MF
definition:
OBSOLETE. A G protein-coupled receptor that is structurally/functionally related to the metabotropic glutamate receptor.


go_id: GO:0001721
term: obsolete intermediate filament associated protein
ontology: CC
definition:
OBSOLETE. Proteins that associate with intermediate filaments and function in the supramolecular organization of cellular intermediate filament networks.


go_id: GO:0001722
term: obsolete type I intermediate filament associated protein
ontology: CC
definition:
OBSOLETE. Low molecular weight (10-45 kDa) proteins that associate with intermediate filaments by lateral binding of the filaments and have the effect of creating tight macrofilament aggregates.


go_id: GO:0001723
term: obsolete type II intermediate filament associated protein
ontology: CC
definition:
OBSOLETE. High molecular weight (100-300 kDa) proteins that associate with intermediate filaments to cross-link them into loose networks.


go_id: GO:0001724
term: obsolete type III intermediate filament associated protein
ontology: CC
definition:
OBSOLETE. Proteins that associate with the ends of intermediate filaments and couple the intermediate filaments to the plasma membrane.


go_id: GO:0001753
term: obsolete adult eye photoreceptor development (sensu Drosophila)
ontology: BP
definition:
OBSOLETE. Development of a photoreceptor, a receptor that responds to light, in the adult Drosophila eye.


go_id: GO:0001950
term: obsolete plasma membrane enriched fraction
ontology: CC
definition:
OBSOLETE. The fraction of cells, prepared by disruptive biochemical methods, that is enriched for plasma membranes.


go_id: GO:0002928
term: obsolete Ada2/Gcn5/Ada3 transcription activator complex
ontology: CC
definition:
OBSOLETE. A multiprotein complex that possesses histone acetyltransferase and is involved in regulation of transcription. Contains either GCN5 or PCAF in a mutually exclusive manner. The budding yeast complex includes Gcn5p, two proteins of the Ada family, and two TBP-associate proteins (TAFs); analogous complexes in other species have analogous compositions, and usually contain homologs of the yeast proteins. Both ATAC- or SAGA (see GO:0000124, SAGA complex) are involved in the acetylation of histone H3K9 and K14 residues.


go_id: GO:0003001
term: obsolete generation of a signal involved in cell-cell signaling
ontology: BP
definition:
OBSOLETE. The cellular process that creates a physical entity or change in state, i.e. a signal, that originates in one cell and is used to transfer information to another cell. This process begins with the initial formation of the signal and ends with the mature form and placement of the signal.


go_id: GO:0003074
term: obsolete regulation of diuresis
ontology: BP
definition:
OBSOLETE. Any process that modulates the rate of diuresis. Diuresis is the process of renal water excretion.


go_id: GO:0003077
term: obsolete negative regulation of diuresis
ontology: BP
definition:
OBSOLETE. Any process that reduces the rate of diuresis. Diuresis is the process of renal water excretion.


go_id: GO:0003078
term: obsolete regulation of natriuresis
ontology: BP
definition:
OBSOLETE. Any process that modulates the frequency, rate, or extent of natriuresis, the process of renal sodium excretion.


go_id: GO:0003080
term: obsolete negative regulation of natriuresis
ontology: BP
definition:
OBSOLETE. Any process that stops, prevents, or decreases the frequency, rate, or extent of natriuresis, the process of renal sodium excretion.


go_id: GO:0003082
term: obsolete positive regulation of renal output by angiotensin
ontology: BP
definition:
OBSOLETE. Any process in which angiotensin directly increases the rate of natriuresis and diuresis in the kidney.


go_id: GO:0003103
term: obsolete positive regulation of diuresis
ontology: BP
definition:
OBSOLETE. Any process that activates or increases the frequency, rate or extent of diuresis. Diuresis is the process of renal water excretion.


go_id: GO:0003107
term: obsolete positive regulation of natriuresis by angiotensin
ontology: BP
definition:
OBSOLETE. The process in which angiotensin increases the rate of natriuresis indirectly via diuresis. Natriuresis is the process of renal sodium excretion.


go_id: GO:0003141
ontology: BP
term:
obsolete transforming growth factor beta receptor signaling pathway involved in determination of lateral mesoderm left/right asymmetry

definition:
OBSOLETE. The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands that contributes to lateral mesoderm left/right asymmetry determination.


go_id: GO:0003256
ontology: BP
term:
obsolete regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation

definition:
OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the differentiation of a myocardial precursor cell.


go_id: GO:0003257
ontology: BP
term:
obsolete positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation

definition:
OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the differentiation of a myocardial precursor cell.


go_id: GO:0003258
ontology: BP
term:
obsolete regulation of transcription from RNA polymerase II promoter involved in endocardial precursor cell differentiation

definition:
OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the differentiation of an endocardial precursor cell.


go_id: GO:0003377
term: obsolete regulation of apoptosis by sphingosine-1-phosphate signaling pathway
ontology: BP
definition:
OBSOLETE. A sphingosine-1-phosphate signaling pathway that modulates the rate, frequency, or extent of apoptosis.


go_id: GO:0003378
term: obsolete regulation of inflammatory response by sphingosine-1-phosphate signaling pathway
ontology: BP
definition:
OBSOLETE. A sphingosine-1-phosphate signaling pathway that modulates the rate, frequency, or extent of the inflammatory response.


go_id: GO:0003673
term: obsolete Gene_Ontology
ontology: BP
definition:
OBSOLETE. A controlled vocabulary that can be applied to all organisms even as knowledge of gene and protein roles in cells is accumulating and changing. GO provides three structured networks of defined terms to describe gene product attributes.


go_id: GO:0003694
term: obsolete plasmid binding
ontology: MF
definition:
OBSOLETE. Interacting selectively with a plasmid, an extrachromosomal genetic element usually characterized as a covalently continuous double stranded DNA molecule found in bacteria and some other microorganisms.


go_id: GO:0003704
term: obsolete specific RNA polymerase II transcription factor activity
ontology: MF
definition:
OBSOLETE. Functions to enable the transcription of specific, or specific sets, of genes by RNA polymerase II.


go_id: GO:0003706
term: obsolete ligand-regulated transcription factor activity
ontology: MF
definition:
OBSOLETE. Functions to enable the transcription of specific, or specific sets, of genes by RNA polymerase II in response to a ligand.


go_id: GO:0003710
term: obsolete transcription activator activity
ontology: MF
definition:
OBSOLETE. Any transcription regulator activity required for initiation or upregulation of transcription.


go_id: GO:0003731
term: obsolete mRNA cap binding
ontology: MF
definition:
OBSOLETE. Interacting selectively with the 7-methylguanosine cap at the 5' end of a nascent messenger RNA transcript.


go_id: GO:0003732
term: obsolete snRNA cap binding
ontology: MF
definition:
OBSOLETE. Interacting selectively with the cap structure at the 5' end of a small nuclear RNA molecule.


go_id: GO:0003754
term: obsolete chaperone activity
ontology: MF
definition:
OBSOLETE. Assists in the correct non-covalent assembly of polypeptide-containing structures in vivo, but is not a component of these assembled structures when they are performing their normal biological function.


go_id: GO:0003759
term: obsolete glycoprotein-specific chaperone activity
ontology: MF
definition:
OBSOLETE. Assists in the correct, non-covalent assembly of glycoproteins in vivo, but is not a component of the assembled structures when performing its normal biological function. Utilizes a lectin site as a means to associate with the unfolded glycoproteins.


go_id: GO:0003762
term: obsolete histone-specific chaperone activity
ontology: MF
definition:
OBSOLETE. Assists in chromatin assembly by chaperoning histones on to replicating DNA, but is not a component of the assembled nucleosome when performing its normal biological function.


go_id: GO:0003763
term: obsolete chaperonin ATPase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. The hydrolysis of ATP involved in maintaining an unfolded polypeptide structure before folding or to entry into mitochondria and chloroplasts.


go_id: GO:0003767
term: obsolete co-chaperone activity
ontology: MF
definition:
OBSOLETE. Co-chaperones are proteins that bind to chaperones and this complex then folds misfolded proteins. Co-chaperones by themselves do not possess chaperone activity.


go_id: GO:0003772
term: obsolete co-chaperonin activity
ontology: MF
definition:
OBSOLETE. Co-chaperonins are proteins that bind to chaperones and this complex then folds misfolded proteins. Co-chaperonins by themselves do not possess chaperone activity.


go_id: GO:0003773
term: obsolete heat shock protein activity
ontology: MF
definition:
OBSOLETE. Any of a group of specific proteins that are synthesized by both prokaryotic and eukaryotic cells after they have been exposed to a temperature that is higher than normal. Other stresses, e.g. free radical damage, have a similar effect. Many members of the hsp family are not induced but are present in all cells. They are characterized by their role as molecular chaperones.


go_id: GO:0003793
term: obsolete defense/immunity protein activity
ontology: MF
definition:
OBSOLETE. Any activity that plays a role in the defense/immune response of an organism against infection and disease.


go_id: GO:0003798
term: obsolete male-specific antibacterial peptide activity
ontology: MF
definition:
OBSOLETE. Inhibits the growth of, or directly kills, bacterial cells, but which is only expressed in males.


go_id: GO:0003802
term: obsolete coagulation factor VIIa activity
ontology: MF
definition:
OBSOLETE. Catalysis of the selective cleavage of one Arg-Ile bond in factor X to form factor Xa, and on factor IX to form factor IXa beta.


go_id: GO:0003804
term: obsolete coagulation factor Xa activity
ontology: MF
definition:
OBSOLETE. Catalysis of the preferential cleavage of Arg-Thr and then Arg-Ile bonds in prothrombin to form thrombin, and on factor VII, which it converts to a two-chain form (factor VIIa).


go_id: GO:0003805
term: obsolete coagulation factor XIa activity
ontology: MF
definition:
OBSOLETE. Catalysis of the selective cleavage of Arg-Ala and Arg-Val bonds in factor IX to form factor IXa.


go_id: GO:0003806
term: obsolete coagulation factor XIIa activity
ontology: MF
definition:
OBSOLETE. Catalysis of the selective cleavage of Arg-Ile bonds in factor VII to form factor VIIa and factor XI to form factor XIa.


go_id: GO:0003807
term: obsolete plasma kallikrein activity
ontology: MF
definition:
OBSOLETE. Catalysis of the selective cleavage of Arg-Xaa and Lys-Xaa bonds, including Lys-Arg and Arg-Ser bonds in (human) kininogen to release bradykinin.


go_id: GO:0003809
term: obsolete thrombin activity
ontology: MF
definition:
OBSOLETE. Catalysis of the preferential cleavage of Arg-Gly; activates fibrinogen to fibrin and releases fibrinopeptide A and B.


go_id: GO:0003812
term: obsolete alternative-complement-pathway C3/C5 convertase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the cleavage of Arg-Ser bond in complement component C3 alpha-chain to yield C3a and C3b, and Arg bond in complement component C5 alpha-chain to yield C5a and C5b.


go_id: GO:0003813
term: obsolete classical-complement-pathway C3/C5 convertase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the selective cleavage of Arg-Ser bond in complement component C3 alpha-chain to form C3a and C3b, and Arg bond in complement component C5 alpha-chain to form C5a and C5b.


go_id: GO:0003815
term: obsolete complement component C1r activity
ontology: MF
definition:
OBSOLETE. Catalysis of the selective cleavage of Lys(or Arg)-Ile bond in complement subcomponent C1s to form the active form of C1s (EC:3.4.21.42).


go_id: GO:0003816
term: obsolete complement component C1s activity
ontology: MF
definition:
OBSOLETE. Catalysis of the cleavage of component C4 to C4a and C4b (Arg-Ala bond), and component C2 to C2a and C2b (Lys-Lys or Arg-Lys bond).


go_id: GO:0003817
term: obsolete complement factor D activity
ontology: MF
definition:
OBSOLETE. Catalysis of the cleavage of component factor B (Arg-Lys) when in complex with C3b or with cobra venom factor (CVF).


go_id: GO:0003818
term: obsolete complement factor I activity
ontology: MF
definition:
OBSOLETE. Catalysis of the inactivation of complement subcomponents C3b, iC3b and C4b by proteolytic cleavage.


go_id: GO:0003840
term: obsolete gamma-glutamyltransferase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: (5-L-glutamyl)-peptide + an amino acid = peptide + 5-L-glutamyl-amino acid.


go_id: GO:0003892
term: obsolete proliferating cell nuclear antigen
ontology: MF
definition:
OBSOLETE. A nuclear protein that associates as a trimer and then interacts with delta DNA polymerase and epsilon DNA polymerase, acting as an auxiliary factor for DNA replication and DNA repair.


go_id: GO:0003931
term: obsolete Rho small monomeric GTPase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. Any member of the Rho subfamily of the RAS superfamily of monomeric GTPases. Proteins in the Rho subfamily are involved in relaying signals from cell-surface receptors to the actin cytoskeleton.


go_id: GO:0003966
term: obsolete RNA-directed DNA polymerase, transposon encoded
ontology: MF
definition:
OBSOLETE. Catalysis of RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time; cannot initiate a chain de novo.


go_id: GO:0004007
term: obsolete heavy metal-exporting ATPase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: heavy metal ion(in) + ATP + H2O = heavy metal ion(out) + ADP + phosphate.


go_id: GO:0004171
term: obsolete deoxyhypusine synthase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: [eIF5A-precursor]-lysine + spermidine = [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine.


go_id: GO:0004178
term: obsolete leucyl aminopeptidase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the release of an N-terminal amino acid, Xaa-Xbb-, in which Xaa is preferably Leu, but may be other amino acids including Pro although not Arg or Lys, and Xbb may be Pro.


go_id: GO:0004179
term: obsolete membrane alanyl aminopeptidase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the release of an N-terminal amino acid, Xaa-Xbb- from a peptide, amide or arylamide. Xaa is preferably Ala, but may be most amino acids including Pro (slow action). When a terminal hydrophobic residue is followed by a prolyl residue, the two may be released as an intact Xaa-Pro dipeptide.


go_id: GO:0004182
term: obsolete carboxypeptidase A activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: peptidyl-L-amino acid + H2O = peptide + L-amino acid. Little or no action with -Asp, -Glu, -Arg, -Lys or -Pro.


go_id: GO:0004183
term: obsolete carboxypeptidase E activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: peptidyl-L-lysine (or peptidyl-L-arginine) + H2O = peptide + L-lysine (or L-arginine). Function is activated by Co2+ and inhibited by 1,10-phenanthroline and other chelating agents.


go_id: GO:0004184
term: obsolete lysine carboxypeptidase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: peptidyl-L-lysine (or peptidyl-L-arginine) + H2O = peptide + L-lysine (or L-arginine). Release of a C-terminal basic amino acid, preferentially lysine; inactivates bradykinin and anaphylatoxins in blood plasma.


go_id: GO:0004187
term: obsolete carboxypeptidase D activity
ontology: MF
definition:
OBSOLETE. Catalysis of the preferential release of a C-terminal arginine or lysine residue. Function is inhibited by diisopropyl fluorophosphate and sensitive to thiol-blocking reagents.


go_id: GO:0004188
term: obsolete serine-type Pro-X carboxypeptidase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the cleavage of a Pro-Xaa bond by a serine-type peptidase mechanism to release a C-terminal amino acid.


go_id: GO:0004189
term: obsolete tubulinyl-Tyr carboxypeptidase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the cleavage of the Glu-Tyr bond to release the C-terminal tyrosine residue from the native tyrosinated tubulin. Inactive on Z-Glu-Tyr.


go_id: GO:0004191
term: obsolete barrierpepsin activity
ontology: MF
definition:
OBSOLETE. Catalysis of the selected cleavage of the Leu6-Lys7 bond in the pheromone alpha-mating factor.


go_id: GO:0004192
term: obsolete cathepsin D activity
ontology: MF
definition:
OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Specificity similar to, but narrower than, that of pepsin A. Does not cleave the Gln4-His5 bond in the B chain of insulin.


go_id: GO:0004193
term: obsolete cathepsin E activity
ontology: MF
definition:
OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Similar to cathepsin D, but slightly broader specificity.


go_id: GO:0004194
term: obsolete pepsin A activity
ontology: MF
definition:
OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Preferential cleavage: hydrophobic, preferably aromatic, residues in P1 and P1' positions. Cleaves Phe1-Val2, Gln4-His5, Glu13-Ala14, Ala14-Leu15, Leu15-Tyr16, Tyr16-Leu17, Gly23-Phe24, Phe24-Phe25 and Phe25-Tyr26 bonds in the B chain of insulin.


go_id: GO:0004196
term: obsolete saccharopepsin activity
ontology: MF
definition:
OBSOLETE. Catalysis of the degradation of gelatin; little activity on hemoglobin. Specificity on B chain of insulin more restricted than pepsin A; does not cleave Phe1-Val2, Gln4-His5 or Gly23-Phe24.


go_id: GO:0004199
term: obsolete caspase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the hydrolysis of a peptide bond on the carboxyl side of an aspartate residue.


go_id: GO:0004201
term: obsolete caspase-1 activity
ontology: MF
definition:
OBSOLETE. Catalysis of the release of interleukin 1-beta by specific cleavage of Asp116-Ala117 and Asp27-Gly28 bonds in precursor. Enzymes with this function can also hydrolyze the terminal bond in the small-molecule substrate, Ac-Tyr-Val-Ala-Asp-NHMec.


go_id: GO:0004208
term: obsolete caspase-3 activity
ontology: MF
definition:
OBSOLETE. Catalysis of the cleavage at the terminal bond of the motif: Asp-Xaa-Xaa-Asp-Xaa. Enzymes with this function are members of the peptidase family C14 and they appear to function in the inactivation of proteins involved in cellular repair and homeostasis during the effector stage of apoptosis.


go_id: GO:0004213
term: obsolete cathepsin B activity
ontology: MF
definition:
OBSOLETE. Catalysis of the hydrolysis of peptide bonds with a broad specificity. Preferentially cleaves the terminal bond of -Arg-Arg-Xaa motifs in small molecule substrates (thus differing from cathepsin L). In addition to being an endopeptidase, shows peptidyl-dipeptidase activity, liberating C-terminal dipeptides.


go_id: GO:0004214
term: obsolete dipeptidyl-peptidase I activity
ontology: MF
definition:
OBSOLETE. Catalysis of the release of an N-terminal dipeptide, Xaa-Xbb from Xaa-Xbb-Xcc, except when Xaa is Arg or Lys, or Xbb or Xcc is Pro.


go_id: GO:0004215
term: obsolete cathepsin H activity
ontology: MF
definition:
OBSOLETE. Catalysis of the hydrolysis of peptide bonds, acting as an aminopeptidase (notably, cleaving Arg-Xaa bonds) as well as an endopeptidase.


go_id: GO:0004216
term: obsolete cathepsin K activity
ontology: MF
definition:
OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Has a broad proteolytic activity. With small-molecule substrates and inhibitors, the major determinant of specificity is P2, which is preferably Leu, Met > Phe, and not Arg.


go_id: GO:0004217
term: obsolete cathepsin L activity
ontology: MF
definition:
OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Specificity close to that of papain. As compared to cathepsin B, cathepsin L exhibits higher activity towards protein substrates, but has little activity on Z-Arg-Arg-NHMec, and no peptidyl-dipeptidase activity.


go_id: GO:0004218
term: obsolete cathepsin S activity
ontology: MF
definition:
OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Similar to cathepsin L, but with much less activity on the terminal bond of Z-Phe-Arg-NHMec, and more activity on the terminal bond of Z-Val-Val-Arg-Xaa compounds.


go_id: GO:0004228
term: obsolete gelatinase A activity
ontology: MF
definition:
OBSOLETE. Catalysis of the cleavage of gelatin type I and collagen types IV, V, VII, X. Cleaves the collagen-like sequence Pro-Gln-Gly-Ile-Ala-Gly-Gln at the Gly-Ile bond.


go_id: GO:0004230
term: obsolete glutamyl aminopeptidase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the release of a N-terminal glutamate (and to a lesser extent aspartate) from a peptide.


go_id: GO:0004231
term: obsolete insulysin activity
ontology: MF
definition:
OBSOLETE. Catalysis of the degradation of insulin, glucagon and other polypeptides. No action on proteins.


go_id: GO:0004232
term: obsolete interstitial collagenase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the preferential cleavage of one bond in native collagen. Cleavage of the triple helix of collagen at about three-quarters of the length of the molecule from the N-terminus, at Gly775-Ile776 in the alpha-1(I) chain. Cleaves synthetic substrates and alpha-macroglobulins at bonds where P1' is a hydrophobic residue.


go_id: GO:0004234
term: obsolete macrophage elastase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the hydrolysis of soluble and insoluble elastin. Specific cleavages are also produced at Ala14-Leu15 and Tyr16-Leu17 in the B chain of insulin.


go_id: GO:0004235
term: obsolete matrilysin activity
ontology: MF
definition:
OBSOLETE. Catalysis of the cleavage of Ala14-Leu15 and Tyr16-Leu17 in B chain of insulin. No action on collagen types I, II, IV and V. Cleaves gelatin chain alpha-2(I) > alpha-1(I).


go_id: GO:0004238
term: obsolete meprin A activity
ontology: MF
definition:
OBSOLETE. Catalysis of the hydrolysis of protein and peptide substrates preferentially on carboxyl side of hydrophobic residues.


go_id: GO:0004239
term: obsolete methionyl aminopeptidase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.


go_id: GO:0004240
term: obsolete mitochondrial processing peptidase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the release of N-terminal transit peptides from precursor proteins imported into the mitochondrion, typically with Arg in position P2.


go_id: GO:0004243
term: obsolete mitochondrial intermediate peptidase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the release of an N-terminal octapeptide as second stage of processing of some proteins imported in the mitochondrion.


go_id: GO:0004244
term: obsolete mitochondrial inner membrane peptidase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the maturation of mitochondrial precursor proteins delivered to the intermembrane space.


go_id: GO:0004245
term: obsolete neprilysin activity
ontology: MF
definition:
OBSOLETE. Catalysis of the preferential cleavage at the amino group of hydrophobic residues in insulin, casein, hemoglobin, and a number of other proteins and polypeptides.


go_id: GO:0004246
term: obsolete peptidyl-dipeptidase A activity
ontology: MF
definition:
OBSOLETE. Catalysis of the release of a C-terminal dipeptide, Xaa-Xbb from oligopeptide-Xaa-Xbb, when Xaa is not Pro, and Xbb is neither Asp nor Glu. Converts angiotensin I to angiotensin II.


go_id: GO:0004250
term: obsolete aminopeptidase I activity
ontology: MF
definition:
OBSOLETE. Catalysis of the release of an N-terminal amino acid, preferably a neutral or hydrophobic one, from a polypeptide. Aminoacyl-arylamides are poor substrates.


go_id: GO:0004251
term: obsolete X-Pro dipeptidase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on Pro-Pro.


go_id: GO:0004253
term: obsolete gamma-renin activity
ontology: MF
definition:
OBSOLETE. Catalysis of the cleavage of the Leu-Leu bond in synthetic tetradecapeptide renin substrate, producing angiotensin I, but not active on natural angiotensinogen. Also hydrolyzes BZ-Arg-para-nitroanilide.


go_id: GO:0004262
term: obsolete cerevisin activity
ontology: MF
definition:
OBSOLETE. Catalysis of the hydrolysis of proteins with broad specificity, and of BZ-Arg-OET > Ac-Tyr-OET. Does not hydrolyze peptide amides.


go_id: GO:0004274
term: obsolete dipeptidyl-peptidase IV activity
ontology: MF
definition:
OBSOLETE. Catalysis of the release of an N-terminal dipeptide, by the hydrolysis of the Xbb-Xcc bond in Xaa-Xbb-Xcc, preferentially when Xbb is Pro, provided Xcc is neither Pro nor hydroxyproline.


go_id: GO:0004276
term: obsolete furin activity
ontology: MF
definition:
OBSOLETE. Catalysis of the release of mature proteins from their proproteins by cleavage of the terminal bond of Arg-Xaa-Yaa-Arg-Z motifs where Xaa can be any amino acid and Yaa is Arg or Lys. Releases albumin, complement component C3 and von Willebrand factor from their respective precursors.


go_id: GO:0004277
term: obsolete granzyme A activity
ontology: MF
definition:
OBSOLETE. Catalysis of the hydrolysis of proteins, including fibronectin, type IV collagen and nucleolin. Preferential cleavage: Arg-Xaa > Lys-Xaa > Phe-Xaa in small molecule substrates.


go_id: GO:0004279
term: obsolete tissue kallikrein activity
ontology: MF
definition:
OBSOLETE. Catalysis of the preferential cleavage of Arg-Xaa bonds in small molecule substrates. Highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-Xaa or Leu-Xaa. The rat enzyme is unusual in liberating bradykinin directly from autologous kininogens by cleavage at two Arg-Xaa bonds.


go_id: GO:0004281
term: obsolete pancreatic elastase II activity
ontology: MF
definition:
OBSOLETE. Catalysis of the preferential cleavage of Leu-Xaa, Met-Xaa and Phe-Xaa. Hydrolyzes elastin.


go_id: GO:0004283
term: obsolete plasmin activity
ontology: MF
definition:
OBSOLETE. Catalysis of the preferential cleavage of Lys-Xaa > Arg-Xaa; higher selectivity than trypsin. Converts fibrin into soluble products.


go_id: GO:0004285
term: obsolete proprotein convertase 1 activity
ontology: MF
definition:
OBSOLETE. Catalysis of the release of protein hormones, neuropeptides and renin from their precursors, generally by cleavage of -Lys-Arg-Xaa at the Arg-Xaa bond.


go_id: GO:0004286
term: obsolete proprotein convertase 2 activity
ontology: MF
definition:
OBSOLETE. Catalysis of the release of protein hormones and neuropeptides from their precursors, generally by cleavage of -Lys-Arg-Xaa at the Arg-Xaa bond.


go_id: GO:0004290
term: obsolete kexin activity
ontology: MF
definition:
OBSOLETE. Catalysis of the cleavage of the Arg-Xaa bond in Lys-Arg-Xaa and Arg-Arg-Xaa to process Yeast alpha-factor pheromone and killer toxin precursors.


go_id: GO:0004291
term: obsolete subtilisin activity
ontology: MF
definition:
OBSOLETE. Catalysis of the hydrolysis of proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. Hydrolyzes peptide amides.


go_id: GO:0004327
term: obsolete formaldehyde dehydrogenase (glutathione) activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: formaldehyde + glutathione + NAD+ = S-formylglutathione + NADH + H+.


go_id: GO:0004374
term: obsolete glycine cleavage system
ontology: MF
definition:
OBSOLETE. Catalysis of the reactions: glycine + lipoylprotein = S-aminomethyldihydrolipoylprotein + carbon dioxide (CO2), followed by S-aminomethyldihydrolipoylprotein + (6S)-tetrahydrofolate = dihydrolipoylprotein + (6R)-5,10-methylenetetrahydrofolate + ammonia. Made up of two components, aminomethyltransferase and glycine dehydrogenase (decarboxylating).


go_id: GO:0004428
term: obsolete inositol or phosphatidylinositol kinase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the phosphorylation of myo-inositol (1,2,3,5/4,6-cyclohexanehexol) or a phosphatidylinositol.


go_id: GO:0004437
term: obsolete inositol or phosphatidylinositol phosphatase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the removal of a phosphate group from phosphorylated myo-inositol (1,2,3,5/4,6-cyclohexanehexol) or a phosphatidylinositol.


go_id: GO:0004442
term: obsolete inositol-1,4,-bisphosphate 3-phosphatase
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: D-myo-inositol 1,3-bisphosphate + H2O = D-myo-inositol 1-monophosphate + phosphate.


go_id: GO:0004443
term: obsolete inositol-1,4,-bisphosphate 4-phosphatase
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: D-myo-inositol 3,4-bisphosphate + H2O = D-myo-inositol 3-monophosphate + phosphate.


go_id: GO:0004444
term: obsolete inositol-1,4,5-trisphosphate 1-phosphatase
ontology: MF
definition:
OBSOLETE. The removal of a phosphate group from the carbon-1 position of D-myo-inositol 1,4,5-trisphosphate.


go_id: GO:0004584
term: obsolete dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the transfer of an alpha-D-mannosyl residue from dolichyl-phosphate D-mannose into membrane lipid-linked oligosaccharide.


go_id: GO:0004600
term: obsolete cyclophilin
ontology: MF
definition:
OBSOLETE. A protein to which cyclosporin A (an immunosuppressant) binds. Possesses peptidyl-prolyl isomerase activity.


go_id: GO:0004624
term: obsolete secreted phospholipase A2 activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a fatty acid anion.


go_id: GO:0004702
term: obsolete signal transducer, downstream of receptor, with serine/threonine kinase activity
ontology: MF
definition:
OBSOLETE. Conveys a signal from an upstream receptor or intracellular signal transducer by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.


go_id: GO:0004716
term: obsolete signal transducer, downstream of receptor, with protein tyrosine kinase activity
ontology: MF
definition:
OBSOLETE. Conveys a signal from an upstream receptor or intracellular signal transducer by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate.


go_id: GO:0004728
term: obsolete signal transducer, downstream of receptor, with protein tyrosine phosphatase activity
ontology: MF
definition:
OBSOLETE. Conveys a signal from an upstream receptor or intracellular signal transducer by catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.


go_id: GO:0004868
term: obsolete serpin
ontology: MF
definition:
OBSOLETE. A superfamily of proteins, many of which inhibit serine proteinases and exhibit a high degree of homology with classical serine proteinase inhibitors such as alpha1-antitrypsin or antithrombin.


go_id: GO:0004871
term: obsolete signal transducer activity
ontology: MF
definition:
OBSOLETE. Conveys a signal across a cell to trigger a change in cell function or state. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.


go_id: GO:0004874
term: obsolete aryl hydrocarbon receptor activity
ontology: MF
definition:
OBSOLETE. Combining with an aryl hydrocarbon and transmitting the signal to initiate a change in cell activity. The aryl hydrocarbon receptor is a ligand-activated transcription factor which translocates to the nucleus to activate transcription upon ligand-binding.


go_id: GO:0004928
term: obsolete frizzled receptor activity
ontology: MF
definition:
OBSOLETE. Combining with a member of the Wnt-family of signaling molecules to initiate a change in cell activity.


go_id: GO:0004929
term: obsolete frizzled-2 receptor activity
ontology: MF
definition:
OBSOLETE. Combining with to a member of the Wnt-family of signaling molecules to initiate a change in cell activity.


go_id: GO:0004986
term: obsolete delta-opioid receptor activity
ontology: MF
definition:
OBSOLETE. Combining with an opioid to initiate a change in cell activity, with the pharmacological characteristics of delta-opioid receptors, including the activity of enkephalins as ligands.


go_id: GO:0004987
term: obsolete kappa-opioid receptor activity
ontology: MF
definition:
OBSOLETE. Combining with an opioid to initiate a change in cell activity, with the pharmacological characteristics of kappa-opioid receptors, including high affinity for dynorphins.


go_id: GO:0004988
term: obsolete mu-opioid receptor activity
ontology: MF
definition:
OBSOLETE. Combining with an opioid to initiate a change in cell activity, with the pharmacological characteristics of mu-opioid receptors, including high affinity for enkephalins and beta-endorphin but low affinity for dynorphins.


go_id: GO:0005057
term: obsolete signal transducer activity, downstream of receptor
ontology: MF
definition:
OBSOLETE. Conveys a signal from an upstream receptor or intracellular signal transducer, converting the signal into a form where it can ultimately trigger a change in the state or activity of a cell.


go_id: GO:0005070
term: obsolete SH3/SH2 adaptor activity
ontology: MF
definition:
OBSOLETE. Interacting selectively and non-covalently and simultaneously with one or more signal transduction molecules, usually acting as a scaffold to bring these molecules into close proximity either using their own SH2/SH3 domains (e.g. Grb2) or those of their target molecules (e.g. SAM68).


go_id: GO:0005072
term: obsolete transforming growth factor beta receptor, cytoplasmic mediator activity
ontology: MF
definition:
OBSOLETE. Activity of any of the molecules that transmit the signal from a TGF-beta receptor through the cytoplasm to the nucleus.


go_id: GO:0005276
term: obsolete vesicular amino acid:proton antiporter activity
ontology: MF
definition:
OBSOLETE. Enables the transfer of a solute or solutes from one side of a vesicle membrane to the other according to the reaction: H+(in) + amino acid(out) = H+(out) + amino acid(in).


go_id: GO:0005311
term: obsolete sodium:dicarboxylate/tricarboxylate symporter activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: (dicarboxylate or tricarboxylate)(out) + Na+(out) = (dicarboxylate or tricarboxylate)(in) + Na+(in).


go_id: GO:0005357
term: obsolete constitutive glucose:proton symporter activity
ontology: MF
definition:
OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose + H+ = glucose + H+. This activity is constitutive and therefore always present, regardless of demand. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.


go_id: GO:0005373
term: obsolete heavy metal ion porter activity
ontology: MF
definition:
OBSOLETE. A transporter of heavy metal ions that utilizes a carrier-mediated process to catalyze uniport, symport or antiport between aqueous phases on either side of a lipid membrane.


go_id: GO:0005395
term: obsolete eye pigment precursor transporter activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: ATP + H2O + eye pigment precursor(in) = ADP + phosphate + eye pigment precursor(out).


go_id: GO:0005490
term: obsolete cytochrome P450
ontology: MF
definition:
OBSOLETE. A cytochrome b that has a sulfur atom ligated to the iron of the prosthetic group (heme-thiolate); enzymes:typically monooxygenases acting on lipophilic substrates.


go_id: GO:0005505
term: obsolete heavy metal binding
ontology: MF
definition:
OBSOLETE. Interacting selectively with a heavy metal, a metal that can form a coordination bond with a protein, as opposed to an alkali or alkaline-earth metal that can only form an ionic bond; this definition includes the following biologically relevant heavy metals: Cd, Co, Cu, Fe, Hg, Mn, Mo, Ni, V, W, Zn.


go_id: GO:0005530
term: obsolete lectin
ontology: MF
definition:
OBSOLETE. Lectins are proteins obtained particularly from the seeds of leguminous plants, but also from many other plant and animal sources, that have binding sites for specific mono or oligosaccharides in cell walls or membranes. They thereby change the physiology of the membrane to cause agglutination, mitosis, or other biochemical changes in the cell.


go_id: GO:0005541
term: obsolete acyl-CoA or acyl binding
ontology: MF
definition:
OBSOLETE. Interacting selectively with acyl-CoA or acyl, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty acyl group, or any group formally derived by removal of a hydroxyl group from the acid function of an organic acid.


go_id: GO:0005553
term: obsolete ubiquitin-ribosomal protein fusion protein
ontology: MF
definition:
OBSOLETE. A protein encoded by some ubiquitin genes which consists of a single copy of ubiquitin fused to a ribosomal protein.


go_id: GO:0005623
term: obsolete cell
ontology: CC
definition:
OBSOLETE. The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.


go_id: GO:0005624
term: obsolete membrane fraction
ontology: CC
definition:
OBSOLETE. That fraction of cells, prepared by disruptive biochemical methods, that includes the plasma and other membranes.


go_id: GO:0005625
term: obsolete soluble fraction
ontology: CC
definition:
OBSOLETE. That fraction of cells, prepared by disruptive biochemical methods, that is soluble in water.


go_id: GO:0005626
term: obsolete insoluble fraction
ontology: CC
definition:
OBSOLETE. That fraction of cells, prepared by disruptive biochemical methods, that is not soluble in water.


go_id: GO:0005627
term: obsolete ascus
ontology: CC
definition:
OBSOLETE. A sac-like fruiting body (ascomycete Fungi); contains ascospores (typically eight in number).


go_id: GO:0005660
term: obsolete delta-DNA polymerase cofactor complex
ontology: CC
definition:
OBSOLETE. A complex of proteins that interacts with delta-DNA polymerase, promoting elongation. In humans it is a heteropentamer of subunits of 140/145, 40, 38, 37 and 36.5 kDa, which form a complex with the proliferating cell nuclear antigen (PCNA) in the presence of ATP.


go_id: GO:0005678
term: obsolete chromatin assembly complex
ontology: CC
definition:
OBSOLETE. Any protein complex that acts in the formation of nucleosomes or higher order chromatin structure.


go_id: GO:0005695
term: obsolete chromatid
ontology: CC
definition:
OBSOLETE. One of the two daughter strands of a duplicated chromosome that become apparent between early prophase and metaphase in mitosis and between diplotene and second metaphase in meiosis.


go_id: GO:0005696
term: obsolete telomere
ontology: CC
definition:
OBSOLETE. A complex of DNA and protein that seals the end of a chromosome. The telomeric DNA consists of simple tandemly repeated sequences specific for each species. Typically one strand is G-rich and the other C-rich. The G-rich strand forms a 3'-terminal overhang, the length of which varies with species. The single strand overhang is bound by a variety of proteins, including telomere capping proteins that bind to the single-stranded DNA.


go_id: GO:0005698
term: obsolete centromere
ontology: CC
definition:
OBSOLETE. The region of a eukaryotic chromosome that is attached to the spindle during nuclear division. It is defined genetically as the region of the chromosome that always segregates at the first division of meiosis; the region of the chromosome in which no crossing over occurs. At the start of M phase, each chromosome consists of two sister chromatids with a constriction at a point which forms the centromere. During late prophase two kinetochores assemble on each centromere, one kinetochore on each sister chromatid.


go_id: GO:0005707
term: obsolete interphase chromosome
ontology: CC
definition:
OBSOLETE. A chromosome found in the cell during interphase of the cell cycle. Chromosomes are usually decondensed during interphase and each long DNA molecule in a chromosome is divided into a large number of discrete domains that are folded differently.


go_id: GO:0005710
term: obsolete metaphase chromosome
ontology: CC
definition:
OBSOLETE. A chromosome found in the cell during metaphase. Typically, sister chromatids are held together at their centromeres and chromosomes are covered with a large number of molecules, including ribonucleoproteins.


go_id: GO:0005724
term: obsolete nuclear telomeric heterochromatin
ontology: CC
definition:
OBSOLETE. Heterochromatic regions of the chromosome found at the telomeres of a chromosome in the nucleus.


go_id: GO:0005792
term: obsolete microsome
ontology: CC
definition:
OBSOLETE. Any of the small, heterogeneous, artifactual, vesicular particles, 50-150 nm in diameter, that are formed when some eukaryotic cells are homogenized and that sediment on centrifugation at 100000 g.


go_id: GO:0005803
term: obsolete secretory vesicle
ontology: CC
definition:
OBSOLETE. A small subcellular vesicle, or granule, surrounded by a single-layered membrane; formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion.


go_id: GO:0005837
term: obsolete 26S proteasome
ontology: CC
definition:
OBSOLETE. A large multisubunit protease found in the cytosol that recognizes, unfolds, and digests protein substrates that have been marked for degradation by the attachment of a ubiquitin group. Individual subcomplexes of the complete 26S proteasome are involved in these different tasks: the ATP-dependent 19S caps are believed to unfold substrates and feed them to the actual protease, the 20S proteasome.


go_id: GO:0005888
term: obsolete proteoglycan integral to plasma membrane
ontology: CC
definition:
OBSOLETE. Penetrating at least one phospholipid bilayer of a plasma membrane and consisting of proteoglycan. Also refers to the state of being buried in the bilayer with no exposure outside the bilayer.


go_id: GO:0005928
term: obsolete apical hemi-adherens junction
ontology: CC
definition:
OBSOLETE. A cell-substrate adherens junction found in the apical region of a cell, such as those found in cuticle-secreting epithelia, which connect the apical membrane to the cuticle.


go_id: GO:0005936
term: obsolete shmoo
ontology: CC
definition:
OBSOLETE. The characteristic projection formed in response to mating pheromone by cells of Saccharomyces and other fungi with similar life cycles. Named after the Al Capp cartoon character, whose shape it resembles.


go_id: GO:0005941
term: obsolete unlocalized protein complex
ontology: CC
definition:
OBSOLETE. Used as a holding place for cellular components whose precise localization is, as yet, unknown, or has not been determined by GO (the latter is the major reason for nodes to have this parent); this term should not be used for annotation of gene products.


go_id: GO:0005949
term: obsolete aminoadipate-semialdehyde dehydrogenase complex
ontology: CC
definition:
OBSOLETE. A heterodimeric enzyme composed of an alpha and beta subunit. Catalyzes the formation of L-2-aminoadipate from L-2-aminoadipate 6-semialdehyde.


go_id: GO:0006100
term: obsolete tricarboxylic acid cycle intermediate metabolic process
ontology: BP
definition:
OBSOLETE. The chemical reactions and pathways involving intermediates of the tricarboxylic acid cycle.


go_id: GO:0006184
term: obsolete GTP catabolic process
ontology: BP
definition:
OBSOLETE. The chemical reactions and pathways resulting in the breakdown of GTP, guanosine triphosphate.


go_id: GO:0006200
term: obsolete ATP catabolic process
ontology: BP
definition:
OBSOLETE. The chemical reactions and pathways resulting in the breakdown of ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.


go_id: GO:0006280
term: obsolete mutagenesis
ontology: BP
definition:
OBSOLETE. The process by which genetic material undergoes a detectable and heritable structural change. There are three categories of mutation: genome mutations, involving addition or subtraction of one or more whole chromosomes; chromosome mutations, which alter the structure of chromosomes; and gene mutations, where the structure of a gene is altered at the molecular level.


go_id: GO:0006286
term: obsolete base-excision repair, base-free sugar-phosphate removal
ontology: BP
definition:
OBSOLETE. Excision of the sugar phosphate residue at an AP site, i.e. a deoxyribose sugar with a missing base, by a phosphodiesterase enzyme.


go_id: GO:0006291
term: obsolete pyrimidine-dimer repair, DNA damage excision
ontology: BP
definition:
OBSOLETE. The excision of damaged DNA during pyrimidine-dimer repair. A large multienzyme complex scans the DNA for a distortion in the double helix rather than for a specific base change. Once a bulky lesion is found, the phosphodiester backbone of the abnormal strand is cleaved on both sides of the distortion, and the portion of the strand containing the lesion (an oligonucleotide) is peeled away from the DNA double helix by a DNA helicase enzyme.


go_id: GO:0006292
term: obsolete pyrimidine-dimer repair, DNA damage recognition
ontology: BP
definition:
OBSOLETE. The location of pyrimidine dimers by a large multienzyme complex that scans the DNA for distortions in the double helix caused by pyrimidine dimers.


go_id: GO:0006299
term: obsolete short patch mismatch repair system
ontology: BP
definition:
OBSOLETE. The repair of mismatched DNA where the gap to be repaired is only one nucleotide. DNA polymerase is the preferred polymerase in short patch repair, performing gap filling DNA synthesis and removal of the 5'-deoxyribose phosphate of the abasic site.


go_id: GO:0006324
term: obsolete S phase-specific histone modification
ontology: BP
definition:
OBSOLETE. The covalent alteration of one or more amino acid residues within a histone protein that takes place during, and results in a modification pattern characteristic of, S phase of the cell cycle.


go_id: GO:0006339
term: obsolete positive regulation of transcription of homeotic gene (trithorax group)
ontology: BP
definition:
OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription of homeotic genes of the trithorax group.


go_id: GO:0006340
term: obsolete negative regulation of transcription of homeotic gene (Polycomb group)
ontology: BP
definition:
OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription of homeotic genes of the Polycomb group.


go_id: GO:0006344
term: obsolete heterochromatin maintenance
ontology: BP
definition:
OBSOLETE. The chromatin organization process that preserves heterochromatin in a stable functional or structural state.


go_id: GO:0006345
term: obsolete negative regulation of chromatin silencing
ontology: BP
definition:
OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of chromatin silencing.


go_id: GO:0006371
term: obsolete mRNA splicing
ontology: BP
definition:
OBSOLETE. The process in which excision of introns from the primary transcript of messenger RNA (mRNA) is followed by ligation of the two exon termini exposed by removal of each intron, so that mRNA consisting only of the joined exons is produced.


go_id: GO:0006387
term: obsolete snRNA capping
ontology: BP
definition:
OBSOLETE. The sequence of enzymatic reactions resulting in the addition of a cap to the 5' end of a nascent snRNA transcript.


go_id: GO:0006439
term: obsolete aminoacyl-tRNA hydrolase reaction
ontology: BP
definition:
OBSOLETE. Hydrolysis of the peptidyl-tRNA by aminoacyl-tRNA hydrolase upon termination of translation. Analogous to usual peptidyl transfer during elongation, except that the acceptor is H2O instead of an aminoacyl-tRNA.


go_id: GO:0006484
term: obsolete protein cysteine-thiol oxidation
ontology: BP
definition:
OBSOLETE. Oxidation of two cysteine sulfhydryl groups (thiols) in one protein by a disulfide bond in a second protein to form a disulfide bond in the first protein and two reduced sulfhydryls in the second. The oxidized cysteines linked by a disulfide bond is known as cystine.


go_id: GO:0006494
term: obsolete protein amino acid terminal glycosylation
ontology: BP
definition:
OBSOLETE. A protein amino acid glycosylation process in which a sugar unit is added to a free alpha-amino or alpha-carboxyl terminal of a peptide.


go_id: GO:0006502
term: obsolete C-terminal protein prenylation
ontology: BP
definition:
OBSOLETE. The covalent or non-covalent attachment of a prenyl group to the carboxy-terminus of a protein; geranyl, farnesyl, or geranylgeranyl groups may be added.


go_id: GO:0006503
term: obsolete C-terminal protein farnesylation
ontology: BP
definition:
OBSOLETE. The covalent or non-covalent attachment of a farnesyl group to the carboxy terminus of a protein.


go_id: GO:0006504
term: obsolete C-terminal protein geranylgeranylation
ontology: BP
definition:
OBSOLETE. The covalent or non-covalent attachment of a geranylgeranyl group to the carboxy-terminus of a protein.


go_id: GO:0006510
term: obsolete ATP-dependent proteolysis
ontology: BP
definition:
OBSOLETE. The hydrolysis of a peptide bond or bonds within a protein using energy from the hydrolysis of ATP.


go_id: GO:0006512
term: obsolete ubiquitin cycle
ontology: BP
definition:
OBSOLETE. The cyclical process by which one or more ubiquitin groups are added to (ubiquitination) and removed from (deubiquitination) a protein.


go_id: GO:0006557
term: obsolete S-adenosylmethioninamine biosynthetic process
ontology: BP
definition:
OBSOLETE. The chemical reactions and pathways resulting in the formation of S-adenosylmethioninamine, (5-deoxy-5-adenosyl)(3-aminopropyl) methylsulfonium salt.


go_id: GO:0006608
term: obsolete snRNP protein import into nucleus
ontology: BP
definition:
OBSOLETE. The directed movement of a small nuclear ribonucleoprotein from the cytoplasm into the nucleus, across the nuclear membrane.


go_id: GO:0006609
term: obsolete mRNA-binding (hnRNP) protein import into nucleus
ontology: BP
definition:
OBSOLETE. The directed movement of a heterogeneous nuclear ribonucleoprotein from the cytoplasm into the nucleus, across the nuclear membrane.


go_id: GO:0006619
term: obsolete SRP-independent cotranslational protein-membrane targeting
ontology: BP
definition:
OBSOLETE. The targeting of proteins to a membrane that occurs during translation and is independent of SRP and signal recognition.


go_id: GO:0006628
term: obsolete mitochondrial translocation
ontology: BP
definition:
OBSOLETE. The translocation of proteins across the mitochondrial membrane. In the presence of a translocating chain, the outer membrane import machinery (MOM complex) and the inner membrane import machinery (MIM complex) form translocation contact sites as a part of the membrane preprotein import machinery.


go_id: GO:0006698
term: obsolete ecdysone modification
ontology: BP
definition:
OBSOLETE. The covalent or conformational alteration of ecdysone, resulting in a change in its properties.


go_id: GO:0006732
term: obsolete coenzyme metabolic process
ontology: BP
definition:
OBSOLETE. The chemical reactions and pathways involving coenzymes, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.


go_id: GO:0006733
term: obsolete oxidoreduction coenzyme metabolic process
ontology: BP
definition:
OBSOLETE. The chemical reactions and pathways involving coenzymes that are required, in addition to an enzyme and a substrate, for an oxidoreductase reaction to proceed.


go_id: GO:0006800
term: obsolete oxygen and reactive oxygen species metabolic process
ontology: BP
definition:
OBSOLETE. The chemical reactions and pathways involving dioxygen (O2), or any of the reactive oxygen species, e.g. superoxide anions (O2-), hydrogen peroxide (H2O2), and hydroxyl radicals (-OH).


go_id: GO:0006802
term: obsolete catalase reaction
ontology: BP
definition:
OBSOLETE. The processes involved in the induction or activation of catalase, an enzyme that catalyzes the conversion of H2O2 into H2O.


go_id: GO:0006823
term: obsolete heavy metal ion transport
ontology: BP
definition:
OBSOLETE. The directed movement of heavy metal ions into, out of or within a cell, or between cells. Heavy metals are those that can form a coordination bond with a protein, as opposed to an alkali or alkaline-earth metal that can only form an ionic bond; this definition includes the following biologically relevant heavy metals: Cd, Co, Cu, Fe, Hg, Mn, Mo, Ni, V, W, Zn.


go_id: GO:0006840
term: obsolete mitochondrial alpha-ketoglutarate/malate transport
ontology: BP
definition:
OBSOLETE. The directed movement of alpha-ketoglutarate and malate into, out of or within a mitochondrion.


go_id: GO:0006894
term: obsolete Golgi to secretory vesicle transport
ontology: BP
definition:
OBSOLETE. The directed movement of proteins from the Golgi to one of two types of secretory vesicle. Continuously secreted proteins are sorted into transport vesicles that fuse with the plasma membrane, releasing their contents by exocytosis. Specialized secretory cells have a second secretory pathway in which soluble proteins and other substances are initially stored in secretory vesicles for later release.


go_id: GO:0006922
term: obsolete cleavage of lamin involved in execution phase of apoptosis
ontology: BP
definition:
OBSOLETE. The proteolytic degradation of lamins during apoptosis, leading to the irreversible breakdown of the nuclear lamina.


go_id: GO:0006923
term: obsolete cleavage of cytoskeletal proteins involved in execution phase of apoptosis
ontology: BP
definition:
OBSOLETE. The proteolytic degradation of cytoskeletal proteins that contributes to apoptosis, leading to the collapse of cytoskeletal structures.


go_id: GO:0006927
term: obsolete transformed cell apoptotic process
ontology: BP
definition:
OBSOLETE. Any apoptotic process in a transformed cell, a cell that has undergone changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm.


go_id: GO:0006928
term: obsolete movement of cell or subcellular component
ontology: BP
definition:
OBSOLETE. The directed, self-propelled movement of a cell or subcellular component without the involvement of an external agent such as a transporter or a pore.


go_id: GO:0006943
term: obsolete chemi-mechanical coupling
ontology: BP
definition:
OBSOLETE. The conversion of chemical energy into mechanical work (as in the contraction of a muscle).


go_id: GO:0006945
term: obsolete nuclear fusion during karyogamy
ontology: BP
definition:
OBSOLETE. The fusion of two haploid nuclei to form a single diploid nucleus, as seen in the yeast mating process.


go_id: GO:0006987
term: obsolete activation of signaling protein activity involved in unfolded protein response
ontology: BP
definition:
OBSOLETE. The conversion of a specific protein, possessing protein kinase and endoribonuclease activities, to an active form as a result of signaling via the unfolded protein response.


go_id: GO:0006988
ontology: BP
definition: OBSOLETE. (Was not defined before being made obsolete).
term:
obsolete unfolded protein response, cleavage of primary transcript encoding UFP-specific transcription factor


go_id: GO:0006989
ontology: BP
definition: OBSOLETE. (Was not defined before being made obsolete).
term:
obsolete unfolded protein response, ligation of mRNA encoding UFP-specific transcription factor by RNA ligase


go_id: GO:0006993
term: obsolete sterol regulatory element binding protein import into nucleus
ontology: BP
definition:
OBSOLETE. The transfer of a sterol regulatory element binding protein (SREBP) into the nucleus, across the nuclear membrane, in response to altered levels of one or more lipids. SREBPs are transcription factors that bind sterol regulatory elements (SREs), DNA motifs found in the promoters of target genes.


go_id: GO:0007011
term: obsolete regulation of cytoskeleton
ontology: BP
definition:
OBSOLETE. Any process that modulates the frequency, rate or extent of the organization, biogenesis or maintenance of the cytoskeleton.


go_id: GO:0007016
term: obsolete cytoskeletal anchoring at plasma membrane
ontology: BP
definition:
OBSOLETE. A cytoskeleton organization process that directly or indirectly links cytoskeletal filaments to the plasma membrane.


go_id: GO:0007068
term: obsolete negative regulation of transcription during mitotic cell cycle
ontology: BP
definition:
OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription that occurs during the mitotic cell cycle.


go_id: GO:0007069
ontology: BP
term:
obsolete negative regulation of transcription from RNA polymerase I promoter during mitotic cell cycle

definition:
OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase I promoter that occurs during the mitotic cell cycle.


go_id: GO:0007070
ontology: BP
term:
obsolete negative regulation of transcription from RNA polymerase II promoter during mitotic cell cycle

definition:
OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter that occurs during the mitotic cell cycle.


go_id: GO:0007071
ontology: BP
term:
obsolete negative regulation of transcription from RNA polymerase III promoter during mitotic cell cycle

definition:
OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase III promoter that occurs during the mitotic cell cycle.


go_id: GO:0007083
term: obsolete mitotic chromosome decondensation
ontology: BP
definition:
OBSOLETE. The cell cycle process in which chromosome structure is altered from the condensed form taken on during mitosis to the relaxed disperse form held in resting cells.


go_id: GO:0007090
term: obsolete regulation of S phase of mitotic cell cycle
ontology: BP
definition:
OBSOLETE. A cell cycle process that modulates the frequency, rate or extent of the progression through the S phase of the mitotic cell cycle.


go_id: GO:0007101
term: obsolete male meiosis centrosome cycle
ontology: BP
definition:
OBSOLETE. Centrosome duplication and separation in the context of a meiotic cell cycle in a male organism.


go_id: GO:0007102
term: obsolete spindle pole body and microtubule cycle (sensu Fungi)
ontology: BP
definition:
OBSOLETE. The dynamics of the spindle pole body and microtubule cytoskeleton during the cell cycle. Includes spindle pole body duplication and separation and formation and elongation of the mitotic spindle. As in, but not restricted to, the fungi (Fungi, ncbi_taxonomy_id:4751).


go_id: GO:0007109
term: obsolete cytokinesis, completion of separation
ontology: BP
definition:
OBSOLETE. The process of finishing cell separation, which results in two physically separated cells.


go_id: GO:0007150
term: obsolete growth pattern
ontology: BP
definition:
OBSOLETE. A process whereby cells develop a specific morphology under a specific set of circumstances.


go_id: GO:0007153
term: obsolete spore germination (sensu Fungi)
ontology: BP
definition:
OBSOLETE. Process of breakdown or opening of the spore-containing structure, modification of the spore wall, and resumption of growth of the spore. As in, but not restricted to, the fungi (Fungi, ncbi_taxonomy_id:4751).


go_id: GO:0007244
term: obsolete MAPKKK cascade (mating sensu Saccharomyces)
ontology: BP
definition:
OBSOLETE. MAPKKK cascade involved in transduction of mating pheromone signal, as described in Saccharomyces.


go_id: GO:0007245
term: obsolete activation of MAPKKK (mating sensu Saccharomyces)
ontology: BP
definition:
OBSOLETE. Upregulation of MAPKKK activity in the context of transduction of mating pheromone signal, as described for Saccharomyces.


go_id: GO:0007246
term: obsolete activation of MAPKK (mating sensu Saccharomyces)
ontology: BP
definition:
OBSOLETE. Upregulation of a MAP kinase kinase in the context of transduction of mating pheromone signal, as described for Saccharomyces.


go_id: GO:0007247
term: obsolete activation of MAPK (mating sensu Saccharomyces)
ontology: BP
definition:
OBSOLETE. Upregulation of MAP kinase activity in the context of transduction of mating pheromone signal, as described for Saccharomyces.


go_id: GO:0007248
term: obsolete nuclear translocation of MAPK (mating sensu Saccharomyces)
ontology: BP
definition:
OBSOLETE. Movement of a MAP kinase to the nucleus in the context of transduction of mating pheromone signal, as described for Saccharomyces.


go_id: GO:0007256
term: obsolete activation of JNKK activity
ontology: BP
definition:
OBSOLETE. The initiation of the activity of the inactive enzyme JUN kinase kinase (JNKK) activity. JNKKs are involved in a signaling pathway that is primarily activated by cytokines and exposure to environmental stress.


go_id: GO:0007261
term: obsolete JAK-induced STAT protein dimerization
ontology: BP
definition:
OBSOLETE. The formation of a dimer of two STAT proteins (Signal Transducers and Activators of Transcription) following their activation by members of the janus activated kinase (JAK) family of tyrosine kinases.


go_id: GO:0007329
term: obsolete positive regulation of transcription from RNA polymerase II promoter by pheromones
ontology: BP
definition:
OBSOLETE. Any process involving pheromones that activates or increases the rate of transcription from an RNA polymerase II promoter.


go_id: GO:0007357
term: obsolete positive regulation of central gap gene transcription
ontology: BP
definition:
OBSOLETE. The activation of genes encoding transcription factors in the central region of an insect embryo by a combination of maternal regulatory signals and interactions among themselves; exemplified by the activation of expression of the Drosophila Kruppel gene by the hunchback and bicoid gene products.


go_id: GO:0007358
term: obsolete establishment of central gap gene boundaries
ontology: BP
definition:
OBSOLETE. Specification of the borders of central gap gene expression mediated largely by the effects of other gap genes; in insects this is exemplified by knirps repression of Kruppel.


go_id: GO:0007360
term: obsolete positive regulation of posterior gap gene transcription
ontology: BP
definition:
OBSOLETE. The activation of genes encoding transcription factors in the posterior region of an insect embryo by a combination of maternal regulatory signals and interactions among themselves; exemplified by the activation of expression of the Drosophila knirps gene.


go_id: GO:0007361
term: obsolete establishment of posterior gap gene boundaries
ontology: BP
definition:
OBSOLETE. Specification of the borders of posterior gap gene expression mediated largely by the effects of other gap genes; in insects this is exemplified by hunchback and tailless repression of knirps.


go_id: GO:0007363
term: obsolete positive regulation of terminal gap gene transcription
ontology: BP
definition:
OBSOLETE. The activation of genes encoding transcription factors at the anterior and posterior ends of an insect embryo by a combination of maternal regulatory signals and interactions among themselves; exemplified by the activation of expression of the Drosophila tailless and huckebein genes.


go_id: GO:0007364
term: obsolete establishment of terminal gap gene boundary
ontology: BP
definition:
OBSOLETE. Specification of the borders of terminal gap gene expression mediated largely by the effects of other gap genes.


go_id: GO:0007468
term: obsolete regulation of rhodopsin gene expression
ontology: BP
definition:
OBSOLETE. Any process that modulates the frequency, rate or extent of rhodopsin gene expression. This includes transcriptional, translational, or posttranslational regulation.


go_id: GO:0007471
term: obsolete prothoracic morphogenesis
ontology: BP
definition:
OBSOLETE. The process by which the anatomical structures of the first or anterior segment of the insect thorax are generated and organized.


go_id: GO:0007515
term: obsolete lymph gland development
ontology: BP
definition:
OBSOLETE. The process whose specific outcome is the progression of the lymph gland over time, from its formation to the mature structure. The lymph gland is a small bean-shaped organ made up of a loose meshwork of reticular tissue in which are enmeshed large numbers of lymphocytes, macrophages and accessory cells. Lymph glands are located along the lymphatic system.


go_id: GO:0007559
term: obsolete histolysis
ontology: BP
definition:
OBSOLETE. The breakdown of tissues; usually, if not always, accompanied by cell death, followed by the complete dissolution of dead tissue.


go_id: GO:0007569
term: obsolete cell aging
ontology: BP
definition:
OBSOLETE. An aging process that has as participant a cell after a cell has stopped dividing. Cell aging may occur when a cell has temporarily stopped dividing through cell cycle arrest (GO:0007050) or when a cell has permanently stopped dividing, in which case it is undergoing cellular senescence (GO:0090398). May precede cell death (GO:0008219) and succeed cell maturation (GO:0048469).


go_id: GO:0007571
term: obsolete age-dependent general metabolic decline
ontology: BP
definition:
OBSOLETE. A developmental process that arises as the cell progresses toward the end of its lifespan and cause changes cellular metabolism, resulting in a decline in cell function; for example, one aspect of general metabolic decline is a decrease in the efficiency of protein synthesis.


go_id: GO:0007574
term: obsolete cell aging (sensu Saccharomyces)
ontology: BP
definition:
OBSOLETE. Process associated with continued cell division (budding) by the mother cell. Age is often measured by counting the number of bud scars on the cell.


go_id: GO:0007577
term: obsolete autophagic death (sensu Saccharomyces)
ontology: BP
definition:
OBSOLETE. This process is a type of programmed cell death pathway similar to apoptosis and necrosis observed in multicellular organisms. It is characterized by cellular enlargement (necrosis) and presence of many autophagic bodies along with degradation of cellular components (nucleus, Golgi, ER), protein, DNA and RNA.


go_id: GO:0007578
term: obsolete aging dependent sterility (sensu Saccharomyces)
ontology: BP
definition:
OBSOLETE. A haploid's inability to mate due to the loss of silencing at the mating-type loci, resulting in expression of both of the normally silent mating-type cassettes.


go_id: GO:0007580
term: obsolete extrachromosomal circular DNA accumulation involved in cell aging
ontology: BP
definition:
OBSOLETE. Increase in abundance, as cells age, of circular DNA molecules that originate in the chromosome but are excised and circularized, often by intramolecular homologous recombination between direct tandem repeats, and replicated independently of chromosomal replication.


go_id: GO:0007590
term: obsolete fat body metabolic process (sensu Insecta)
ontology: BP
definition:
OBSOLETE. The chemical reactions and pathways involving the fat body. A fat body is a fat-containing cellular structure which serves as an energy reserve. As in, but not restricted to, the true insects (Insecta, ncbi_taxonomy_id:50557).


go_id: GO:0007592
term: obsolete protein-based cuticle development
ontology: BP
definition:
OBSOLETE. Synthesis and deposition of a protein-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this is found in Caenorhabditis elegans.


go_id: GO:0007607
term: obsolete taste perception
ontology: BP
definition:
OBSOLETE. The series of events required for the chemical composition of a soluble stimulus to be received and converted to a molecular signal.


go_id: GO:0007609
term: obsolete perception of mechanical stimulus
ontology: BP
definition:
OBSOLETE. The series of events by which a mechanical stimulus is received by a cell and converted into a molecular signal.


go_id: GO:0007627
term: obsolete larval behavior (sensu Insecta)
ontology: BP
definition:
OBSOLETE. Behavior in a larval form of an organism, an immature organism that must undergo metamorphosis to assume adult characteristics, as seen in insects.


go_id: GO:0008002
term: obsolete lamina lucida
ontology: CC
definition:
OBSOLETE. The electron-lucent layer of the basal lamina adjacent to the basal plasma membrane of the cells that rest on the lamina.


go_id: GO:0008004
term: obsolete lamina reticularis
ontology: CC
definition:
OBSOLETE. A layer of the basal lamina that contains collagen fibrils and connects the basal lamina to the underlying connective tissue.


go_id: GO:0008025
term: obsolete diazepam binding inhibitor activity
ontology: MF
definition:
OBSOLETE. The diazepam binding inhibitor is a 10kDa 86-residue polypeptide that acts as an endogenous ligand for a mitochondrial receptor (formerly regarded as a peripheral benzodiazepine binding site) in steroidogenic cells and regulates stimulation of steroidogenesis by tropic hormones. It also binds to the GABA-A receptor and modulates glucose-dependent insulin secretion and synthesis of acyl-CoA esters.


go_id: GO:0008034
term: obsolete lipoprotein binding
ontology: MF
definition:
OBSOLETE. Binding to a conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.


go_id: GO:0008042
term: obsolete iron-sulfur electron transfer carrier
ontology: MF
definition:
OBSOLETE. An iron-sulfur protein that serves as an electron acceptor and electron donor in an electron transport system.


go_id: GO:0008100
term: obsolete lipophorin
ontology: MF
definition:
OBSOLETE. Any member of the major class of lipid-transporting proteins found in the hemolymph of insects.


go_id: GO:0008125
term: obsolete pancreatic elastase I activity
ontology: MF
definition:
OBSOLETE. Catalysis of the hydrolysis of proteins, including elastin. Preferential cleavage: Ala-Xaa.


go_id: GO:0008129
term: obsolete actinidain activity
ontology: MF
definition:
OBSOLETE. Catalysis of the hydrolysis of proteins with broad specificity for peptide bonds, with preference for a residue bearing a large hydrophobic side chain at the P2 position. Does not accept Val at P1'.


go_id: GO:0008130
term: obsolete neutrophil collagenase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the cleavage of interstitial collagens in the triple helical domain. Unlike EC:3.4.24.7, this enzyme cleaves type III collagen more slowly than type I.


go_id: GO:0008141
term: obsolete puparial glue (sensu Diptera)
ontology: MF
definition:
OBSOLETE. A glue which attaches the pupae to the substrate during metamorphosis, as in, but not restricted to, the true flies (Diptera, ncbi_taxonomy_id:7147).


go_id: GO:0008144
term: obsolete drug binding
ontology: MF
definition:
OBSOLETE. Binding to a drug, a naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism;typically used in the diagnosis, prevention, or treatment of disease.


go_id: GO:0008148
term: obsolete negative transcription elongation factor activity
ontology: MF
definition:
OBSOLETE. Any activity that decreases the rate of transcription elongation, the addition of ribonucleotides to an RNA molecule following transcription initiation.


go_id: GO:0008159
term: obsolete positive transcription elongation factor activity
ontology: MF
definition:
OBSOLETE. Any activity that increases the rate of transcription elongation, the addition of ribonucleotides to an RNA molecule following transcription initiation.


go_id: GO:0008223
term: obsolete flagellum
ontology: CC
definition:
OBSOLETE. Long whiplike or feathery structures borne either singly or in groups by the motile cells of many bacteria and unicellular eukaryotes and by the motile male gametes of many eukaryotic organisms, which propel the cell through a liquid medium.


go_id: GO:0008229
term: obsolete opsonin activity
ontology: MF
definition:
OBSOLETE. Binds to microorganisms or other particulate material (for example, foreign erythrocytes) to increase the susceptibility of the latter to phagocytosis.


go_id: GO:0008246
term: obsolete electron transfer flavoprotein
ontology: MF
definition:
OBSOLETE. Works in conjunction with acyl-CoA dehydrogenase to catalyze the oxidation of CoA and reduce ubiquinone. Part of the mitochondrial electron transport system.


go_id: GO:0008337
term: obsolete selectin
ontology: MF
definition:
OBSOLETE. A class of cell adhesion molecules that bind to carbohydrate via a lectin-like domain; integral membrane glycoproteins.


go_id: GO:0008341
term: obsolete response to cocaine (sensu Insecta)
ontology: BP
definition:
OBSOLETE. A change in state or activity of a mature individual as the result of a cocaine stimulus. As in, but not restricted to, the true insects (Insecta, ncbi_taxonomy_id:50557).


go_id: GO:0008423
term: obsolete bleomycin hydrolase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the inactivation of bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a peptide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred.


go_id: GO:0008435
term: obsolete anticoagulant activity
ontology: MF
definition:
OBSOLETE. Functions to retard or prevent coagulation. Often used in the context of blood or milk coagulation.


go_id: GO:0008438
term: obsolete 1-phosphatidylinositol-5-phosphate kinase
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: diphosphate + a purine nucleoside = phosphate + a purine mononucleotide.


go_id: GO:0008450
term: obsolete O-sialoglycoprotein endopeptidase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the hydrolysis of O-sialoglycoproteins; cleaves the -Arg31-Asp32- bond in glycophorin A. Does not cleave unglycosylated proteins, desialylated glycoproteins or glycoproteins that are only N-glycosylated.


go_id: GO:0008451
term: obsolete X-Pro aminopeptidase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the release of an N-terminal amino acid, including proline, that is linked with proline, even from a dipeptide or tripeptide.


go_id: GO:0008462
term: obsolete endopeptidase Clp activity
ontology: MF
definition:
OBSOLETE. Catalysis of the hydrolysis of proteins to small peptides in the presence of ATP and magnesium. Alpha-casein is the usual test substrate. In the absence of ATP, only oligopeptides shorter than five residues are cleaved, for example, succinyl-Leu-Tyr-NHMec which is cleaved at the Tyr-NHMec bond, and Leu-Tyr-Leu-Tyr-Trp which is cleaved at the second Leu-Typ bond (cleavage of the Tyr-Leu and Tyr-Trp bonds also occurs).


go_id: GO:0008464
term: obsolete gamma-glutamyl hydrolase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the cleavage of a gamma-glutamyl bond to release an unsubstituted C-terminal amino acid.


go_id: GO:0008472
term: obsolete metallocarboxypeptidase D activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: peptidyl-L-lysine (or peptidyl-L-arginine) + H2O = peptide + L-lysine (or L-arginine). Function is activated by Co2+; inhibited by guanidinoethylmercaptosuccinic acid.


go_id: GO:0008498
term: obsolete phospholipid scrambling
ontology: MF
definition:
OBSOLETE. The trans-bilayer migration of phospholipids accelerated by a phospholipid scramblase upon binding calcium ions.


go_id: GO:0008533
term: obsolete astacin activity
ontology: MF
definition:
OBSOLETE. Catalysis of the hydrolysis of peptide bonds in substrates containing five or more amino acids, preferentially with Ala in P1', and Pro in P2'.


go_id: GO:0008538
term: obsolete proteasome activator activity
ontology: MF
definition:
OBSOLETE. Catalysis of the activation of the proteasome, a large multisubunit complex which performs regulated ubiquitin-dependent cytosolic and nuclear proteolysis.


go_id: GO:0008539
term: obsolete proteasome inhibitor activity
ontology: MF
definition:
OBSOLETE. Stops, prevents or reduces the activity of the proteasome complex. The proteasome complex performs regulated ubiquitin-dependent cytosolic and nuclear proteolysis.


go_id: GO:0008547
term: obsolete protein-synthesizing GTPase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. A GTPase involved in protein synthesis. In the initiation factor complex, it is IF-2b (98 kDa) that binds GTP and subsequently hydrolyzes it in prokaryotes. In eukaryotes, it is eIF-2 (150 kDa) that binds GTP. In the elongation phase, the GTP-hydrolyzing proteins are the EF-Tu polypeptide of the prokaryotic transfer factor (43 kDa), the eukaryotic elongation factor EF-1a (53 kDa), the prokaryotic EF-G (77 kDa), the eukaryotic EF-2 (70-110 kDa) and the signal recognition particle that play a role in endoplasmic reticulum protein synthesis (325 kDa). EF-Tu and EF1a catalyze binding of aminoacyl-tRNA to the ribosomal A-site, while EF-G and EF-2 catalyze the translocation of peptidyl-tRNA from the A-site to the P-site. GTPase activity is also involved in polypeptide release from the ribosome with the aid of the pRFs and eRFs.


go_id: GO:0008548
term: obsolete signal-recognition-particle GTPase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. Activity is associated with the signal-recognition particle, a protein and RNA-containing structure involved in endoplasmic reticulum-associated protein synthesis.


go_id: GO:0008549
term: obsolete dynamin GTPase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. An enzyme that is involved in endocytosis and is instrumental in pinching off membrane vesicles.


go_id: GO:0008550
term: obsolete tubulin GTPase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. An intrinsic activity of alpha-tubulin involved in tubulin folding, division plane formation in prokaryotic cells and others.


go_id: GO:0008552
term: obsolete zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: Me2+(in) + ATP = Me2+(out) + ADP + phosphate, where Me is Zn2+, Cd2+, Co2+, Ni2+ or Pb2+.


go_id: GO:0008563
term: obsolete alpha-factor sex pheromone exporter
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: ATP + H2O + alpha-factor(in) = ADP + phosphate + alpha-factor(out). The export of the alpha-factor sex pheromone by an ABC-type (ATP-binding cassette-type) ATPase, characterized by the presence of two similar ATP-binding domains, that does not undergo phosphorylation during the transport process.


go_id: GO:0008565
term: obsolete protein transporter activity
ontology: MF
definition:
OBSOLETE. Enables the directed movement of proteins into, out of or within a cell, or between cells.


go_id: GO:0008567
term: obsolete dynein ATPase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. The hydrolysis of ATP by dynein that provides the energy for the movement of organelles (endosomes, lysosomes, mitochondria) along microtubules to the centrosome.


go_id: GO:0008570
term: obsolete myosin ATPase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. The hydrolysis of ATP by myosin that provides the energy for actomyosin contraction.


go_id: GO:0008571
term: obsolete non-chaperonin molecular chaperone ATPase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. This is a highly diverse group of enzymes that perform many functions that are similar to those of chaperonins. They comprise a number of heat-shock-cognate proteins. They are also active in clathrin uncoating and in the oligomerization of actin.


go_id: GO:0008572
term: obsolete nucleoplasmin ATPase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. The hydrolysis of ATP required for the ATP-dependent assembly of nucleosome cores, in decondensation of sperm chromatin and in other histone-involving processes.


go_id: GO:0008573
term: obsolete peroxisome-assembly ATPase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. ATP hydrolysis to import and assemble peroxisome components into the organelle.


go_id: GO:0008575
term: obsolete proteasome ATPase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. The hydrolysis of ATP for channel gating and polypeptide unfolding before proteolysis in the proteasome. Six ATPase subunits are present in the regulatory particle (RP) of 26S proteasome.


go_id: GO:0008576
term: obsolete vesicle-fusing ATPase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. The hydrolysis of ATP by an AAA-ATPase, involved in the heterotypic fusion of membrane vesicles with target membranes and the homotypic fusion of various membrane compartments.


go_id: GO:0008634
term: obsolete negative regulation of survival gene product expression
ontology: BP
definition:
OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of survival gene product expression; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level.


go_id: GO:0008636
term: obsolete activation of caspase activity by protein phosphorylation
ontology: BP
definition:
OBSOLETE. Upregulation of the activity of a caspase, a group of cysteine proteases involved in apoptosis, by the addition of a phosphate group.


go_id: GO:0008638
term: obsolete protein tagging activity
ontology: MF
definition:
OBSOLETE. Covalent addition of a specific tagging molecule to a protein, targeting the tagged protein for some fate e.g. degradation.


go_id: GO:0008648
term: obsolete tachykinin
ontology: MF
definition:
OBSOLETE. A family of hormones that stimulate secretion of saliva and cause smooth muscle contraction and vasodilation.


go_id: GO:0008724
term: obsolete DNA topoisomerase IV activity
ontology: MF
definition:
OBSOLETE. Catalysis of the ATP-independent breakage of DNA, followed by passage and rejoining. It also catalyzes the relaxation of supercoiled DNA, and the decatenation and unknotting of DNA in vivo.


go_id: GO:0008846
term: obsolete endopeptidase La activity
ontology: MF
definition:
OBSOLETE. Catalysis of the hydrolysis of large proteins such as globin, casein and denatured serum albumin, in presence of ATP.


go_id: GO:0008943
term: obsolete glyceraldehyde-3-phosphate dehydrogenase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reactions: glyceraldehyde 3-phosphate + phosphate + NAD(P)+ = 3-phospho-D-glyceroyl-phosphate + NAD(P)H + H+, and glyceraldehyde 3-phosphate + H2O + NAD(P)+ = 3-phospho-D-glycerate + NAD(P)H + H+.


go_id: GO:0008944
term: obsolete oligopeptidase A activity
ontology: MF
definition:
OBSOLETE. Catalysis of the hydrolysis of oligopeptides, with broad specificity. Gly or Ala commonly occur as P1 or P1' residues, but more distant residues are also important, as is shown by the fact that Z-Gly-Pro-Gly-Gly-Pro-Ala is cleaved at the Gly-Gly bond, but not Z-(Gly)5.


go_id: GO:0008945
term: obsolete oligopeptidase B activity
ontology: MF
definition:
OBSOLETE. Catalysis of the hydrolysis of Arg-Xaa and Lys-Xaa bonds in oligopeptides, even when P1' residue is proline.


go_id: GO:0008947
term: obsolete omptin activity
ontology: MF
definition:
OBSOLETE. Catalysis of the preferential cleavage of Xaa-Yaa in which both Xaa and Yaa are Arg or Lys.


go_id: GO:0008956
term: obsolete peptidyl-dipeptidase Dcp activity
ontology: MF
definition:
OBSOLETE. Catalysis of the hydrolysis of unblocked, C-terminal dipeptides from oligopeptides, with broad specificity. Does not hydrolyze bonds in which P1' is Pro, or both P1 and P1' are Gly.


go_id: GO:0008975
term: obsolete pitrilysin activity
ontology: MF
definition:
OBSOLETE. Catalysis of the preferential cleavage of Tyr16-Leu17 and Phe25-Tyr26 bonds of oxidized insulin B chain. Also acts on other substrates of Molecular weight less than 7 kDa such as insulin and glucagon.


go_id: GO:0008978
term: obsolete prepilin peptidase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the cleavage of a Gly-Phe bond to release an N-terminal, basic peptide of 5-8 residues from type IV prepilin, and then N-methylates the new N-terminal amino group, the methyl donor being S-adenosyl-L-methionine.


go_id: GO:0008985
term: obsolete pyruvate dehydrogenase (cytochrome) activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: pyruvate + ferricytochrome b1 + H2O = CO2 + acetate + ferrocytochrome b1.


go_id: GO:0008991
term: obsolete serine-type signal peptidase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the cleavage of a signal peptide from a protein precursor by a serine endopeptidase mechanism.


go_id: GO:0009004
term: obsolete signal peptidase I activity
ontology: MF
definition:
OBSOLETE. Catalysis of the cleavage of N-terminal leader sequences from secreted and periplasmic proteins precursor.


go_id: GO:0009005
term: obsolete signal peptidase II activity
ontology: MF
definition:
OBSOLETE. Catalysis of the cleavage of N-terminal leader sequences from membrane prolipoproteins. Hydrolyzes the terminal bond of Xaa-Xbb-Xbb-Cys, in which Xaa is hydrophobic (preferably Leu), Xbb is often Ser or Ala, Xcc is often Gly or Ala, and the Cys is alkylated on sulfur with a diacylglyceryl group.


go_id: GO:0009023
term: obsolete tRNA sulfurtransferase
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: L-cysteine + activated-tRNA = L-serine + tRNA containing a thionucleotide.


go_id: GO:0009049
term: obsolete aspartic-type signal peptidase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the cleavage of a signal peptide from a protein precursor by an aspartic endopeptidase mechanism.


go_id: GO:0009076
term: obsolete histidine family amino acid biosynthetic process
ontology: BP
definition:
OBSOLETE. The chemical reactions and pathways resulting in the formation of amino acids of the histidine family.


go_id: GO:0009077
term: obsolete histidine family amino acid catabolic process
ontology: BP
definition:
OBSOLETE. The chemical reactions and pathways resulting in the breakdown of amino acids of the histidine family.


go_id: GO:0009108
term: obsolete coenzyme biosynthetic process
ontology: BP
definition:
OBSOLETE. The chemical reactions and pathways resulting in the formation of coenzymes, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.


go_id: GO:0009109
term: obsolete coenzyme catabolic process
ontology: BP
definition:
OBSOLETE. The chemical reactions and pathways resulting in the breakdown of coenzymes, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.


go_id: GO:0009278
term: obsolete murein sacculus
ontology: CC
definition:
OBSOLETE. A peptidoglycan polymer that forms the shape-determining structure of the cell all of Gram-negative bacteria.


go_id: GO:0009280
term: obsolete cell wall inner membrane
ontology: CC
definition:
OBSOLETE. In Gram-negative bacteria the membrane that separates the cytoplasm from the murein sacculus.


go_id: GO:0009296
term: obsolete flagellum assembly
ontology: BP
definition:
OBSOLETE. The assembly of a flagellum. In bacteria, this is a whiplike motility appendage present on the surface of some species; in eukaryotes, flagella are threadlike protoplasmic extensions used to propel flagellates and sperm. Flagella are composed of flagellin and have the same basic structure as cilia but are longer in proportion to the cell and present in much smaller numbers.


go_id: GO:0009323
term: obsolete ribosomal-protein-alanine N-acetyltransferase complex
ontology: CC
definition:
OBSOLETE. An enzyme complex that catalyzes the transfer of an acetyl group to ribosomal-protein alanine, forming ribosomal-protein acetylalanine.


go_id: GO:0009327
term: obsolete NAD(P)+ transhydrogenase complex (AB-specific)
ontology: CC
definition:
OBSOLETE. A protein complex that possesses NAD(P)+ transhydrogenase (AB-specific) activity. Homodimeric, trimeric, and heterotetrameric complexes have been identified.


go_id: GO:0009335
term: obsolete holo-[acyl-carrier protein] synthase complex
ontology: CC
definition:
OBSOLETE. An enzyme complex that catalyzes the formation of holo-[acyl-carrier protein] from CoA and apo-[acyl-carrier protein].


go_id: GO:0009351
term: obsolete dihydrolipoamide S-acyltransferase complex
ontology: CC
definition:
OBSOLETE. An enzyme complex that catalyzes the transfer of an acyl group from coenzyme A to dihydrolipoamide.


go_id: GO:0009354
term: obsolete dihydrolipoamide S-succinyltransferase complex
ontology: CC
definition:
OBSOLETE. An enzyme complex that catalyzes the transfer of succinyl-CoA to dihydrolipoamide to form S-succinyldihydrolipoamide. The enzyme is a component of the multienzyme 2-oxoglutarate dehydrogenase complex.


go_id: GO:0009367
term: obsolete prepilin peptidase complex
ontology: CC
definition:
OBSOLETE. An enzyme complex that catalyzes the cleavage of a Gly-Phe bond to release an N-terminal, basic peptide of 5-8 residues from type IV prepilin, and then N-methylates the new N-terminal amino group.


go_id: GO:0009373
term: obsolete regulation of transcription by pheromones
ontology: BP
definition:
OBSOLETE. Any process involving pheromones that modulates the frequency, rate or extent of transcription.


go_id: GO:0009377
term: obsolete HslUV protease activity
ontology: MF
definition:
OBSOLETE. Catalysis of the ATP-dependent hydrolysis of peptide bonds in substrates including E. coli SulA and misfolded proteins.


go_id: GO:0009400
term: obsolete signal transducer, downstream of receptor, with serine/threonine phosphatase activity
ontology: MF
definition:
OBSOLETE. Conveys a signal from an upstream receptor or intracellular signal transducer by catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.


go_id: GO:0009405
term: obsolete pathogenesis
ontology: BP
definition:
OBSOLETE. The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.


go_id: GO:0009412
term: obsolete response to heavy metal
ontology: BP
definition:
OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heavy metal stimulus. Heavy metals are those metals that can form a coordination bond with a protein; this definition includes the following biologically relevant heavy metals: Cd, Co, Cu, Fe, Hg, Mn, Mo, Ni, V, W, Zn.


go_id: GO:0009457
term: obsolete flavodoxin
ontology: MF
definition:
OBSOLETE. A group of small electron carriers, characteristic of anaerobic bacteria, photosynthetic bacteria, cyanobacteria and eukaryotic algae. Contain flavin mononucleotide.


go_id: GO:0009458
term: obsolete cytochrome
ontology: MF
definition:
OBSOLETE. A hemeprotein whose characteristic mode of action involves transfer of reducing equivalents associated with a reversible change in oxidation state of the prosthetic group. This redox change involves a single electron, reversible equilibrium between the Fe(II) and Fe(III) states of the central iron atom.


go_id: GO:0009461
term: obsolete cytochrome c
ontology: MF
definition:
OBSOLETE. A cytochrome containing heme bound to the protein by one or, more (commonly two) thioether bonds involving sulfhydryl groups of cysteine residues.


go_id: GO:0009462
term: obsolete cytochrome d
ontology: MF
definition:
OBSOLETE. A cytochrome in which the prosthetic group is a tetrapyrrolic chelate of iron in which the degree of conjugation of double bonds is less than in porphyrin. This definition would appear to include siroheme proteins (e.g. nitrite and sulfite reductases), but these are not cytochromes.


go_id: GO:0009463
term: obsolete cytochrome b/b6
ontology: MF
definition:
OBSOLETE. Diheme cytochrome b; cytochrome b has the hemes b(562) and b(566) and is a component of the mitochondrial respiratory chain complex III. Cytochrome b6 is a component of bc complex acting between photosystems II and I of photosynthesis.


go_id: GO:0009477
term: obsolete cytochrome c1
ontology: MF
definition:
OBSOLETE. A cytochrome c that is an integral component of the mitochondrial respiratory complex III. Functions as an electron donor to cytochrome c.


go_id: GO:0009479
term: obsolete cytochrome f
ontology: MF
definition:
OBSOLETE. A cytochrome c that is characteristic of green plants and transfers electrons to plastocyanin.


go_id: GO:0009481
term: obsolete aa3-type cytochrome c oxidase
ontology: MF
definition:
OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 4 ferrocytochrome c + O2 = 4 ferricytochrome c + 2 H2O.


go_id: GO:0009487
term: obsolete glutaredoxin
ontology: MF
definition:
OBSOLETE. A small disulfide-containing redox protein that serves as a glutathione-disulfide oxidoreductase.


go_id: GO:0009488
term: obsolete amicyanin
ontology: MF
definition:
OBSOLETE. A copper-containing protein that acts as an electron carrier between methylamine dehydrogenase and cytochrome c.


go_id: GO:0009489
term: obsolete rubredoxin
ontology: MF
definition:
OBSOLETE. A low molecular weight mononuclear iron protein involved in electron transfer, with an iron tetrahedrally coordinated by the sulfurs of four conserved cysteine residues.


go_id: GO:0009490
term: obsolete mononuclear iron electron carrier
ontology: MF
definition:
OBSOLETE. A mononuclear iron entity that serves as an electron acceptor and electron donor in an electron transport system.


go_id: GO:0009502
term: obsolete photosynthetic electron transport chain
ontology: CC
definition:
OBSOLETE. A series of membrane-linked oxidation-reduction reactions in which electrons are transferred from an initial electron donor through a series of intermediates to a final electron acceptor (usually oxygen).


go_id: GO:0009565
term: obsolete germination
ontology: BP
definition:
OBSOLETE. The physiological and developmental changes by a seed, spore, pollen grain (microspore), or zygote that occur after release from dormancy, and encompassing events prior to and including the first visible indications of growth.


go_id: GO:0009766
term: obsolete primary charge separation
ontology: BP
definition:
OBSOLETE. In the photosynthetic reaction centers, primary charge separation is initiated by the excitation of a molecule followed by the transfer of an electron to an electron acceptor molecule following energy transfer from light harvesting complexes.


go_id: GO:0009770
term: obsolete primary charge separation in photosystem I
ontology: BP
definition:
OBSOLETE. Energized reaction-center P700 chlorophylls on photosystem I donate an electron to a loosely bound Quinone acceptor molecule X, on the stromal surface of the thylakoid membrane. The result is charge separation; a negative charge on the stromal side of the thylakoid membrane and a positive charge on the luminal side.


go_id: GO:0009771
term: obsolete primary charge separation in photosystem II
ontology: BP
definition:
OBSOLETE. Energized reaction-center P680 chlorophylls on photosystem II donate an electron to a loosely bound acceptor molecule, the quinone Q, on the stromal surface of the thylakoid membrane. The result is charge separation; a negative charge on the stromal side of the thylakoid membrane and a positive charge on the luminal side.


go_id: GO:0009781
term: obsolete photosynthetic water oxidation
ontology: BP
definition:
OBSOLETE. Processes by which a molecule of water is oxidized during photosynthesis. P680+, the photochemically oxidized reaction-center chlorophyll of PSII, is a strong biological oxidant. The reduction potential of P680+ is more positive than that of water, and thus it can oxidize water to give O2 and H+ ions. The oxygen escapes as a gas while the H+ ions remain in solution inside the thylakoid vesicle.


go_id: GO:0009839
term: obsolete SCF complex substrate recognition subunit
ontology: CC
definition:
OBSOLETE. The portion of the SCF ubiquitin ligase complex that contains sites required for recognition (and recruitment) of the substrate to the complex.


go_id: GO:0009858
term: obsolete compatible pollen-pistil interaction
ontology: BP
definition:
OBSOLETE. An interaction between a pollen grain and pistil that results in unimpeded growth of the pollen tube through the stigma and style.


go_id: GO:0009869
term: obsolete incompatible pollen-pistil interaction
ontology: BP
definition:
OBSOLETE. An interaction between a pollen grain and pistil that results in inhibition of pollen germination/growth.


go_id: GO:0009872
term: obsolete gametophytic self-incompatibility
ontology: BP
definition:
OBSOLETE. A mechanism that functions to prevent self-fertilization in flowering plants that is determined by the diploid genotype of the parent plant. In sporophytic incompatibility the pollen does not germinate, consequently fertilization does not take place.


go_id: GO:0009936
term: obsolete expansin
ontology: MF
definition:
OBSOLETE. A group of proteins located within the cell walls of plants, both dicots and grasses, that play an essential role in loosening cell walls during cell growth. They are hydrophobic, non glycosylated proteins of about 30kDa.


go_id: GO:0009980
term: obsolete glutamate carboxypeptidase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the release of C-terminal glutamate residues from a wide range of N-acylating groups, including peptidyl, aminoacyl, benzoyl, benzyloxycarbonyl, folyl and pteroyl groups.


go_id: GO:0010131
term: obsolete sucrose catabolic process, using invertase or sucrose synthase
ontology: BP
definition:
OBSOLETE. The chemical reactions and pathways resulting in the breakdown of sucrose by the enzymatic action of either invertase or sucrose synthase.


go_id: GO:0010140
term: obsolete adenine, hypoxanthine and their nucleoside salvage
ontology: BP
definition:
OBSOLETE. The pathway by which adenine, hypoxanthine and their nucleosides from purine nucleotides breakdown are converted back to purine nucleotides. The salvage pathway is important where there is no de-novo purine nucleotide biosynthesis.


go_id: GO:0010141
term: obsolete guanine, xanthine and their nucleoside salvage
ontology: BP
definition:
OBSOLETE. The pathway by which guanine, xanthine and their nucleoside from purine nucleotides breakdown are converted back to purine nucleotides. The pathway is important in cells where there is no de-novo purine nucleotides biosynthesis.


go_id: GO:0010149
term: obsolete senescence
ontology: BP
definition:
OBSOLETE. A preprogrammed process associated with the dismantling of an anatomical structure and an overall decline in metabolism. This may include the breakdown of organelles, membranes and other cellular components. An example of this process is found in Arabidopsis thaliana, when older leaves or floral organs are shed.


go_id: GO:0010153
term: obsolete polar cell elongation
ontology: BP
definition:
OBSOLETE. Cell expansion that results in an increase in cell size along the axis of an organ in a polarized fashion.


go_id: GO:0010156
term: obsolete sporocyte morphogenesis
ontology: BP
definition:
OBSOLETE. Formation and development of sporocyte, the haploid spores of angiosperms which are initiated by the differentiation of a subset of floral cells into sporocytes, which then undergo meiotic divisions to form microspores and megaspores.


go_id: GO:0010194
term: obsolete microRNA metabolic process
ontology: BP
definition:
OBSOLETE. The chemical reactions and pathways involving microRNA, a large family of 21-22 nucleotide non-coding RNAs with presumed post-transcriptional regulatory activity.


go_id: GO:0010195
term: obsolete microRNA biosynthetic process
ontology: BP
definition:
OBSOLETE. The chemical reactions and pathways resulting in the formation of microRNA, a large family of 21-22 nucleotide non-coding RNAs with presumed post-transcriptional regulatory activity.


go_id: GO:0010260
term: obsolete animal organ senescence
ontology: BP
definition:
OBSOLETE. The process that occurs in an animal organ near the end of its active life that is associated with the dismantling of cell components and membranes, and an overall decline in metabolism.


go_id: GO:0010320
term: obsolete arginine/lysine endopeptidase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the hydrolysis of peptide linkages in oligopeptides or polypeptides by a reaction mechanism in which arginine or lysine residues act as nucleophiles.


go_id: GO:0010503
term: obsolete negative regulation of cell cycle arrest in response to nitrogen starvation
ontology: BP
definition:
OBSOLETE. Any process that stops, prevents or reduces the frequency or rate of cell cycle arrest in response to nitrogen starvation.


go_id: GO:0010504
term: obsolete regulation of cell cycle arrest in response to nitrogen starvation
ontology: BP
definition:
OBSOLETE. Any process that modulates the frequency, rate or extent of cell cycle arrest in response to nitrogen starvation.


go_id: GO:0010505
term: obsolete positive regulation of cell cycle arrest in response to nitrogen starvation
ontology: BP
definition:
OBSOLETE. Any process that increases the frequency or rate of cell cycle arrest in response to nitrogen starvation.


go_id: GO:0010670
term: obsolete positive regulation of oxygen and reactive oxygen species metabolic process
ontology: BP
definition:
OBSOLETE. Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving dioxygen (O2), or any of the reactive oxygen species, e.g. superoxide anions (O2-), hydrogen peroxide (H2O2), and hydroxyl radicals (-OH).


go_id: GO:0010671
term: obsolete negative regulation of oxygen and reactive oxygen species metabolic process
ontology: BP
definition:
OBSOLETE. Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving dioxygen (O2), or any of the reactive oxygen species, e.g. superoxide anions (O2-), hydrogen peroxide (H2O2), and hydroxyl radicals (-OH).


go_id: GO:0010679
term: obsolete cinnamic acid biosynthetic process involved in salicylic acid metabolism
ontology: BP
definition:
OBSOLETE. The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid, which is then utilized in the metabolism of salicylic acid.


go_id: GO:0010680
term: obsolete cinnamic acid biosynthetic process involved in coumarin metabolism
ontology: BP
definition:
OBSOLETE. The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid, which is then utilized in the metabolism of coumarin.


go_id: GO:0010681
term: obsolete cinnamic acid biosynthetic process involved in stilbene metabolism
ontology: BP
definition:
OBSOLETE. The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid, which is then utilized in the metabolism of stilbene.


go_id: GO:0010682
term: obsolete cinnamic acid biosynthetic process involved in flavonoid metabolism
ontology: BP
definition:
OBSOLETE. The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid, which is then utilized in the metabolism of flavonoids.


go_id: GO:0010702
term: obsolete regulation of histolysis
ontology: BP
definition:
OBSOLETE. Any process that modulates the rate, frequency or extent of the breakdown of tissues; usually, if not always, accompanied by cell death.


go_id: GO:0010703
term: obsolete negative regulation of histolysis
ontology: BP
definition:
OBSOLETE. Any process that decreases the rate, frequency or extent of the breakdown of tissues; usually, if not always, accompanied by cell death.


go_id: GO:0010735
term: obsolete positive regulation of transcription via serum response element binding
ontology: BP
definition:
OBSOLETE. Any process that increases the frequency, rate or extent of the specifically regulated synthesis of RNA from DNA encoding a specific set of genes as a result of a transcription factor interacting with a serum response element (SRE). A serum response element is a short sequence with dyad symmetry found in the promoters of some of the cellular immediate-early genes, regulated by serum.


go_id: GO:0010834
term: obsolete telomere maintenance via telomere shortening
ontology: BP
definition:
OBSOLETE. Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins and shortening the telomeric DNA.


go_id: GO:0010843
term: obsolete promoter binding
ontology: MF
definition:
OBSOLETE. Binding to a regulatory region composed of the transcription start site and binding sites for transcription factor complexes of the basal transcription machinery.


go_id: GO:0010847
term: obsolete regulation of chromatin assembly
ontology: BP
definition:
OBSOLETE. Any process the modulates the frequency, rate or extent of chromatin assembly. Chromatin assembly is the assembly of DNA, histone proteins, and other associated proteins into chromatin structure, beginning with the formation of the basic unit, the nucleosome, followed by organization of the nucleosomes into higher order structures, ultimately giving rise to a complex organization of specific domains within the nucleus.


go_id: GO:0010848
term: obsolete regulation of chromatin disassembly
ontology: BP
definition:
OBSOLETE. Any process that modulates the frequency, rate or extent of chromatin disassembly. Chromatin disassembly is the controlled breakdown of chromatin from a higher order structure into its simpler subcomponents, DNA, histones, and other proteins.


go_id: GO:0010860
term: obsolete proteasome regulator activity
ontology: MF
definition:
OBSOLETE. Modulates the activity of the proteasome complex. The proteasome complex performs regulated ubiquitin-dependent cytosolic and nuclear proteolysis.


go_id: GO:0010861
term: obsolete thyroid hormone receptor coactivator activity
ontology: MF
definition:
OBSOLETE. The function of a transcription cofactor that activates transcription in conjunction with a thyroid hormone-dependent nuclear receptor from a RNA polymerase II promoter; does not bind DNA itself.


go_id: GO:0010869
term: obsolete regulation of receptor biosynthetic process
ontology: BP
definition:
OBSOLETE. Any process that modulates the frequency or rate of receptor biosynthesis. Receptor biosynthesis is the collection of chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.


go_id: GO:0010870
term: obsolete positive regulation of receptor biosynthetic process
ontology: BP
definition:
OBSOLETE. Any process that increases the frequency or rate of receptor biosynthesis. Receptor biosynthesis is the collection of chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.


go_id: GO:0010871
term: obsolete negative regulation of receptor biosynthetic process
ontology: BP
definition:
OBSOLETE. Any process that decreases the frequency or rate of receptor biosynthesis. Receptor biosynthesis is the collection of chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.


go_id: GO:0010926
term: obsolete anatomical structure formation
ontology: BP
definition:
OBSOLETE. The process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structure is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.


go_id: GO:0010978
term: obsolete gene silencing involved in chronological cell aging
ontology: BP
definition:
OBSOLETE. Any transcriptional or post-transcriptional process, arising in non-dividing cells as they age, carried out at the cellular level that results in long-term gene inactivation.


go_id: GO:0015002
term: obsolete heme-copper terminal oxidase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the four-electron reduction of dioxygen (O2) to water, coupled to generation of a proton electrochemical gradient across a membrane.


go_id: GO:0015003
term: obsolete copper electron carrier
ontology: MF
definition:
OBSOLETE. A copper-containing entity that serves as an electron acceptor and electron donor in an electron transport system.


go_id: GO:0015005
term: obsolete azurin
ontology: MF
definition:
OBSOLETE. Brilliant blue copper-containing protein of low molecular weight found in some bacteria; thought to transfer electrons to cytochrome oxidase. This definition includes pseudoazurin.


go_id: GO:0015006
term: obsolete plastocyanin
ontology: MF
definition:
OBSOLETE. A copper-containing electron carrier acting between cytochrome b(6)-f and P700 of photosystem I.


go_id: GO:0015007
term: obsolete electron carrier, chlorophyll electron transport system
ontology: MF
definition:
OBSOLETE. A molecular entity that serves as an electron acceptor and electron donor in a chlorophyll electron transport system.


go_id: GO:0015032
term: obsolete storage protein import into fat body
ontology: BP
definition:
OBSOLETE. The incorporation of hemolymph proteins by cells of the fat body of holometabolous insects, during the final larval stage. Uptake of these proteins prepares the insect for pupation and metamorphosis, since insect pupae do not feed and therefore depend on material that has been accumulated during larval life.


go_id: GO:0015034
term: obsolete cytochrome P450 activity
ontology: MF
definition:
OBSOLETE. A cytochrome b-like protein that has a sulfur atom ligated to the iron of the prosthetic group (heme-thiolate); enzymes: typically monooxygenases acting on, typically, lipophilic substrates. The characteristic mode of action of these enzymes is not electron transfer (some P450 enzymes probably do not even involve the reversible Fe(II)/Fe(III) equilibrium), but rather oxygen atom transfer.


go_id: GO:0015040
term: obsolete electron transfer flavoprotein, group I
ontology: MF
definition:
OBSOLETE. An electron transfer flavoprotein that functions as a housekeeping protein that links acyl-CoA dehydrogenase reactions with the respiratory chain, such as in the fatty acid degradation pathway.


go_id: GO:0015041
term: obsolete electron transfer flavoprotein, group II
ontology: MF
definition:
OBSOLETE. An electron transfer flavoprotein that functions as a housekeeping protein that is synthesized only under certain specific growth conditions and receives electrons from the oxidation of specific substrates, e.g. trimethylamine, carnitine and in nitrogen fixation.


go_id: GO:0015051
term: obsolete X-opioid receptor activity
ontology: MF
definition:
OBSOLETE. Combining with an opioid to initiate a change in cell activity, with the pharmacological characteristics of X-opioid receptors.


go_id: GO:0015053
term: obsolete opsin
ontology: MF
definition:
OBSOLETE. Hydrophobic glycoprotein to which 11-cis-retinal binds as a Schiff base (in rhodopsin) or 3,4-didehydro-11-cis-retinal binds as a Schiff base in cyanopsin and porphyropsin.


go_id: GO:0015072
term: obsolete phosphatidylinositol 3-kinase, class I, catalyst activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 3-phosphate.


go_id: GO:0015076
term: obsolete heavy metal ion transporter activity
ontology: MF
definition:
OBSOLETE. Enables the directed movement of heavy metal ions into, out of or within a cell, or between cells. Heavy metals are those that can form a coordination bond with a protein, as opposed to an alkali or alkaline-earth metal that can only form an ionic bond; this definition includes the following biologically relevant heavy metals: Cd, Co, Cu, Fe, Hg, Mn, Mo, Ni, V, W, Zn.


go_id: GO:0015176
term: obsolete holin
ontology: MF
definition:
OBSOLETE. Primary function of holins appears to be transport of murein hydrolases across the cytoplasmic membrane to the cell wall of bacteria, where these enzymes hydrolyze the cell wall polymer as a prelude to cell lysis. When chromosomally encoded, these enzymes are therefore autolysins. Holins may also facilitate leakage of electrolytes and nutrients from the cell cytoplasm, thereby promoting cell death. Some catalyze export of nucleases.


go_id: GO:0015223
term: obsolete vitamin or cofactor transporter activity
ontology: MF
definition:
OBSOLETE. Enables the directed transport of vitamins or cofactors into, out of or within a cell, or between cells.


go_id: GO:0015289
term: obsolete pore-forming toxin activity
ontology: MF
definition:
OBSOLETE. Catalysis of the transport of electrolytes and other small molecules across a cell membrane. They are synthesized by one cell and secreted for insertion into the membrane of another cell where they form transmembrane pores. They may exert their toxic effects by allowing the free flow of electrolytes and other small molecules across the membrane, or they may allow entry into the target cell cytoplasm of a toxin protein that ultimately kills the cell.


go_id: GO:0015301
term: obsolete anion:anion antiporter activity
ontology: MF
definition:
OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: anion A(out) + anion B(in) = anion A(in) + anion B(out).


go_id: GO:0015305
term: obsolete lactose, galactose:proton symporter activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: (lactose or galactose)(out) + H+(out) = (lactose or galactose)(in) + H+(in).


go_id: GO:0015307
term: obsolete drug:proton antiporter activity
ontology: MF
definition:
OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + drug(in) = H+(in) + drug(out).


go_id: GO:0015331
term: obsolete asparagine/glutamine permease activity
ontology: MF
definition:
OBSOLETE. Catalysis of the stereospecific transfer of asparagine or glutamine across a biological membrane.


go_id: GO:0015335
term: obsolete heavy metal ion:hydrogen symporter activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: Me2+(out) + H+(out) = Me2+(in) + H+(in), where Me2+ is Fe2+, Zn2+, Mn2+, Cu2+, Cd2+, Co2+, Ni2+ or Pb2+.


go_id: GO:0015336
term: obsolete high affinity metal ion uptake transporter activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: Me2+(out) + H+(out) = Me2+(in) + H+(in). Me can be Fe2+, Mn2+, Zn2+, Cu2+, Cd2+, Ni2+ or Co2+.


go_id: GO:0015337
term: obsolete low affinity metal ion uptake transporter activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: Me2+(out) + H+(out) = Me2+(in) + H+(in). Me can be Mn2+ or Cu2+.


go_id: GO:0015339
term: obsolete cobalt, zinc uptake permease activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: (Zn2+ or Co2+)(out) = (Zn2+ or Co2+)(in). The activity is driven by proton motive force, possibly by proton symport.


go_id: GO:0015340
term: obsolete zinc, cadmium uptake permease activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: (Zn2+ or Cd2+)(out) = (Zn2+ or Cd2+)(in). The activity is driven by proton motive force, possibly by proton symport.


go_id: GO:0015342
term: obsolete zinc, iron permease activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: (Zn2+ or Fe2+)(out) = (Zn2+ or Fe2+)(in), probably powered by proton motive force.


go_id: GO:0015352
term: obsolete secondary active sterol transmembrane transporter activity
ontology: MF
definition:
OBSOLETE. Enables the transfer of sterol from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.


go_id: GO:0015372
term: obsolete glutamate/aspartate:sodium symporter activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: (glutamate or aspartate)(out) + Na+(out) = (glutamate or aspartate)(in) + Na+(in).


go_id: GO:0015376
term: obsolete betaine/GABA:sodium symporter activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: (betaine or gamma-aminobutyric acid)(out) + Na+(out) = (betaine or gamma-aminobutyric acid)(in) + Na+(in).


go_id: GO:0015442
term: obsolete hydrogen-/sodium-translocating ATPase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: ATP + H2O + (Na+ or H+)(in) = ADP + phosphate + (Na+ or H+)(out).


go_id: GO:0015468
term: obsolete colicin
ontology: MF
definition:
OBSOLETE. Plasmid-encoded bacteriocins which are produced by enteric bacteria. Exert a lethal effect on other bacteria including E. coli strains that lack the Col plasmid. Bind to a cell surface receptor and are transported into the periplasm via an energy-dependent process involving a TonB- or TolA-dependent hetero-oligomeric protein complex. Some colicins kill their target cell by inserting into the cytoplasmic membrane where they form voltage-sensitive (trans-negative) channels that depolarize and deenergize the cell, and thereby kill it.


go_id: GO:0015469
term: obsolete channel-forming toxin activity
ontology: MF
definition:
OBSOLETE. A toxin that exerts its effects by forming a channel in a membrane that allows the unregulated passage of substances into and out of the cell.


go_id: GO:0015470
term: obsolete bacteriocin activity
ontology: MF
definition:
OBSOLETE. Polypeptide antibiotic secreted by bacteria and able to kill bacteria of susceptible strains after absorption by specific cell surface receptor.


go_id: GO:0015472
term: obsolete fimbrium-specific chaperone activity
ontology: MF
definition:
OBSOLETE. Assists in the correct assembly of fimbria, extracellular organelles that are used to attach a bacterial cell to a surface, but is not a component of the fimbrium when performing its normal biological function.


go_id: GO:0015477
term: obsolete receptor porin activity
ontology: MF
definition:
OBSOLETE. A porin of the bacterial outer membrane that forms transmembrane pores and transports relatively large molecules from the external milieu to the periplasm in an energized process. Energizing of transport across the outer membrane requires a heterotrimeric complex of proteins, the TonB-ExbB-ExbD complex, or in some cases, the TolA-TolQ-TolR complex. Energizing requires proton motive force across the cytoplasmic membrane.


go_id: GO:0015480
term: obsolete secretin (sensu Bacteria)
ontology: MF
definition:
OBSOLETE. Secretins are Gram-negative bacterial outer membrane proteins that form multimeric pores through which macromolecules, usually proteins, can pass. Form homomultimeric ring structures, 10-20 subunits per complex, with large central pores (inner diameters of 5-10 nm).


go_id: GO:0015491
term: obsolete cation:cation antiporter activity
ontology: MF
definition:
OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cation A(out) + cation B(in) = cation A(in) + cation B(out).


go_id: GO:0015500
term: obsolete threonine/serine:sodium symporter activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: (threonine or serine)(out) + Na+(out) = (threonine or serine)(in) + Na+(in).


go_id: GO:0015521
term: obsolete bicyclomycin/sulfathiazole:hydrogen antiporter activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: (bicyclomycin or sulfathiazole)(in) + H+(out) = (bicyclomycin or sulfathiazole)(out) + H+(in).


go_id: GO:0015522
term: obsolete hydrophobic uncoupler:proton antiporter activity
ontology: MF
definition:
OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hydrophobic uncoupler(in) + H+(out) = hydrophobic uncoupler(out) + H+(in). Hydrophobic uncouplers include CCCP, benzalkonium and SDS.


go_id: GO:0015524
term: obsolete L-arabinose/beta-D-thiogalactopyranoside:hydrogen antiporter activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: H+(out) + (L-arabinose or beta-D-thiogalactopyranoside)(in) = H+(in) + (L-arabinose or beta-D-thiogalactopyranoside)(out).


go_id: GO:0015525
ontology: MF
definition: OBSOLETE. (Was not defined before being made obsolete).
term:
obsolete carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity


go_id: GO:0015534
term: obsolete proline/glycine/betaine:hydrogen/sodium symporter activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: (proline, glycine or betaine)(out) + (H+ or Na+)(out) = (proline, glycine or betaine)(in) + (H+ or Na+)(in).


go_id: GO:0015560
term: obsolete L-idonate/D-gluconate:hydrogen symporter activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: (L-idonate or D-gluconate)(out) + H+(out) = (L-iodonate or D-gluconate)(in) + H+(in).


go_id: GO:0015583
term: obsolete beta-glucoside [arbutin-salicin-cellobiose] permease activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: protein N-phosphohistidine + beta-glucoside(out) = protein histidine + beta-glucoside phosphate(in). The beta-glucoside may be arbutin, salicin or cellobiose.


go_id: GO:0015596
term: obsolete glycine betaine/proline porter activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: ATP + H2O + quaternary amine(out) = ADP + phosphate + quaternary amine(in).


go_id: GO:0015597
term: obsolete histidine/arginine/lysine/ornithine porter activity
ontology: MF
definition:
OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + polar amino acid(out) = ADP + phosphate + polar amino acid(in).


go_id: GO:0015602
term: obsolete leucine/isoleucine/valine porter activity
ontology: MF
definition:
OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + nonpolar amino acid(out) = ADP + phosphate + nonpolar amino acid(in).


go_id: GO:0015634
term: obsolete lipopolysaccharide exporter activity
ontology: MF
definition:
OBSOLETE. Enables the transfer of lipopolysaccharide from the inside of the cell to the outside of the cell across a membrane. A lipopolysaccharide is any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide.


go_id: GO:0015644
term: obsolete lipoprotein antitoxin
ontology: MF
definition:
OBSOLETE. Binds to a lipoprotein toxin, which is usually derived from a microorganism, thereby neutralizing it.


go_id: GO:0015875
term: obsolete vitamin or cofactor transport
ontology: BP
definition:
OBSOLETE. The directed movement of vitamins or cofactors into, out of or within a cell, or between cells.


go_id: GO:0015915
term: obsolete fatty-acyl group transport
ontology: BP
definition:
OBSOLETE. The directed movement of fatty acyl groups into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A fatty acyl group is any acyl group derived from a fatty acid.


go_id: GO:0015933
term: obsolete flavin-containing electron transporter
ontology: MF
definition:
OBSOLETE. An oxidoreductase which contains either flavin-adenine dinucleotide or flavin mononucleotide as a prosthetic group, utilizes either NADH or NADPH and transfers electrons to other electron transfer proteins.


go_id: GO:0015981
term: obsolete passive proton transport, down the electrochemical gradient
ontology: BP
definition:
OBSOLETE. The passive movement of protons from areas of high proton concentration and electrical potential to areas where concentration and electrical potential are low.


go_id: GO:0015982
term: obsolete antiport
ontology: BP
definition:
OBSOLETE. The process of coupled solute translocation in which two solutes equilibrate across an osmotic barrier, the translocation of solute being coupled to the translocation of the other in the opposite direction.


go_id: GO:0015983
term: obsolete symport
ontology: BP
definition:
OBSOLETE. The process of solute translocation in which two solutes equilibrate across an osmotic barrier, and the translocation of one solute is coupled to the translocation of the other in the same direction.


go_id: GO:0015993
term: obsolete molecular hydrogen transport
ontology: BP
definition:
OBSOLETE. The directed movement of molecular hydrogen (H2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0016065
term: obsolete humoral defense mechanism (sensu Protostomia)
ontology: BP
definition:
OBSOLETE. The specific immune response mediated by antibodies. As in, but not restricted to, the taxon Protostomia (Protostomia, ncbi_taxonomy_id:33317).


go_id: GO:0016086
term: obsolete allatostatin
ontology: MF
definition:
OBSOLETE. Peptide hormones produced by the corpora allata of insects that reversibly inhibit the production of juvenile hormone.


go_id: GO:0016088
term: obsolete insulin
ontology: MF
definition:
OBSOLETE. A polypeptide hormone that stimulates glucose uptake by muscle and adipose tissue, and promotes glycogenesis, lipogenesis and the synthesis of proteins and nucleic acids.


go_id: GO:0016172
term: obsolete antifreeze activity
ontology: MF
definition:
OBSOLETE. Inhibits the formation of ice crystals in organismal fluid (e.g. blood) at below freezing exogenous temperatures.


go_id: GO:0016187
term: obsolete synaptic vesicle internalization
ontology: BP
definition:
OBSOLETE. Internalization of the contents of a synaptic vesicle into the postsynaptic membrane following endocytosis.


go_id: GO:0016227
term: obsolete tRNA sulfurtransferase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: L-cysteine + 'activated' tRNA = L-serine + tRNA containing a thionucleotide.


go_id: GO:0016252
term: obsolete nonspecific RNA polymerase II transcription factor activity
ontology: MF
definition:
OBSOLETE. Any function that supports transcription of genes by RNA polymerase II, and is not specific to a particular gene or gene set.


go_id: GO:0016265
term: obsolete death
ontology: BP
definition:
OBSOLETE. A permanent cessation of all vital functions: the end of life; can be applied to a whole organism or to a part of an organism.


go_id: GO:0016275
term: obsolete [cytochrome c]-arginine N-methyltransferase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: S-adenosyl-L-methionine + (cytochrome c)-arginine = S-adenosyl-L-homocysteine + (cytochrome c)-N(omega)-methyl-arginine.


go_id: GO:0016284
term: obsolete alanine aminopeptidase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the release of an N-terminal amino acid, preferentially alanine, from an oligopeptide or polypeptide.


go_id: GO:0016285
term: obsolete cytosol alanyl aminopeptidase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the release of an N-terminal amino acid, preferentially alanine, from a wide range of peptides, amides and arylamides.


go_id: GO:0016299
term: obsolete regulator of G-protein signaling activity
ontology: MF
definition:
OBSOLETE. Inhibits signal transduction the GTPase activity of G-protein alpha subunits, thereby driving them into their inactive GDP-bound form.


go_id: GO:0016304
term: obsolete phosphatidylinositol 3-kinase activity, class I
ontology: MF
definition:
OBSOLETE. A heterodimeric phosphoinositide 3-kinase which can phosphorylate phosphatidylinositol, phosphatidylinositol-4-phosphate or phosphatidylinositol-4,5-bisphosphate. Also possesses intrinsic protein kinase activity.


go_id: GO:0016305
term: obsolete phosphatidylinositol 3-kinase activity, class II
ontology: MF
definition:
OBSOLETE. A phosphoinositide 3-kinase which can phosphorylate phosphatidylinositol and phosphatidylinositol-4-phosphate; the human form can phosphorylate phosphatidylinositol-4,5-bisphosphate in the presence of phosphatidylserine.


go_id: GO:0016313
term: obsolete inositol-1,4,5-trisphosphate phosphatase
ontology: MF
definition:
OBSOLETE. The removal of one of the phosphate groups from an inositol triphosphate to produce an inositol bisphosphate.


go_id: GO:0016329
term: obsolete apoptosis regulator activity
ontology: MF
definition:
OBSOLETE. The function held by products which directly regulate any step in the process of apoptosis.


go_id: GO:0016458
term: obsolete gene silencing
ontology: BP
definition:
OBSOLETE. Any process carried out at the cellular level that results in either long-term transcriptional repression via action on chromatin structure or RNA mediated, post-transcriptional repression of gene expression.


go_id: GO:0016466
term: obsolete hydrogen-translocating A-type ATPase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out). Found in archae.


go_id: GO:0016467
term: obsolete hydrogen-translocating F-type ATPase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out). Found in eukaryotic mitochondria and chloroplasts and in bacteria.


go_id: GO:0016468
term: obsolete sodium-translocating F-type ATPase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: ATP + H2O + Na+(in) = ADP + phosphate + Na+(out). Found in eukaryotic mitochondria and chloroplasts and in bacteria.


go_id: GO:0016506
term: obsolete apoptosis activator activity
ontology: MF
definition:
OBSOLETE. The function held by products which directly activate any step in the process of apoptosis.


go_id: GO:0016512
term: obsolete endothelin-converting enzyme 1 activity
ontology: MF
definition:
OBSOLETE. Catalysis of the formation of endothelin 1 by cleavage of the Trp21-Val22 bond in the precursor.


go_id: GO:0016518
term: obsolete interleukin-14 receptor activity
ontology: MF
definition:
OBSOLETE. Combining with interleukin-14 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


go_id: GO:0016541
term: obsolete intein
ontology: MF
definition:
OBSOLETE. Intervening protein sequence excised from a protein precursor in protein splicing; inteins catalyze their own excision and many also possess endonuclease activity.


go_id: GO:0016550
term: obsolete insertion or deletion editing
ontology: BP
definition:
OBSOLETE. The insertion into or deletion from an RNA molecule of nucleotide residues not encoded in DNA; takes place during or after transcription.


go_id: GO:0016551
term: obsolete posttranscriptional insertion or deletion editing
ontology: BP
definition:
OBSOLETE. The insertion into or deletion from an RNA molecule of nucleotide residues not encoded in DNA; takes place after transcription.


go_id: GO:0016552
term: obsolete cotranscriptional insertion or deletion editing
ontology: BP
definition:
OBSOLETE. The insertion into or deletion from an RNA molecule of nucleotide residues not encoded in DNA; takes place during transcription.


go_id: GO:0016565
term: obsolete general transcriptional repressor activity
ontology: MF
definition:
OBSOLETE. Any activity that stops or downregulates transcription of genes globally, and is not specific to a particular gene or gene set.


go_id: GO:0016566
term: obsolete specific transcriptional repressor activity
ontology: MF
definition:
OBSOLETE. Any activity that stops or downregulates transcription of specific genes or sets of genes.


go_id: GO:0016569
term: obsolete covalent chromatin modification
ontology: BP
definition:
OBSOLETE. The alteration of DNA or protein in chromatin by the covalent addition or removal of chemical groups.


go_id: GO:0016582
term: obsolete non-covalent chromatin modification
ontology: BP
definition:
OBSOLETE. The alteration of DNA or protein in chromatin by the non-covalent addition or removal of chemical groups.


go_id: GO:0016584
term: obsolete nucleosome positioning
ontology: BP
definition:
OBSOLETE. Ordering of successions of nucleosomes into regular arrays so that nucleosomes are positioned at defined distances from one another.


go_id: GO:0016626
term: obsolete oxidoreductase activity, acting on the aldehyde or oxo group of donors, other acceptors
ontology: MF
definition:
OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces an acceptor other than NAD, NADP, oxygen, an iron-sulfur protein, disulphide or a cytochrome.


go_id: GO:0016637
term: obsolete oxidoreductase activity, acting on the CH-CH group of donors, other acceptors
ontology: MF
definition:
OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces an acceptor other than quinone or related compound, a cytochrome, an iron-sulfur protein, NAD, NADP or oxygen.


go_id: GO:0016644
term: obsolete oxidoreductase activity, acting on the CH-NH2 group of donors, other acceptors
ontology: MF
definition:
OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces an acceptor other than a cytochrome, disulfide, an iron-sulfur protein, NAD, NADP or oxygen.


go_id: GO:0016650
term: obsolete oxidoreductase activity, acting on the CH-NH group of donors, other acceptors
ontology: MF
definition:
OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces an acceptor other than quinone or similar compound, disulfide, NAD, NADP, oxygen or a flavin.


go_id: GO:0016659
term: obsolete oxidoreductase activity, acting on NADH or NADPH, other acceptor
ontology: MF
definition:
OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces an acceptor other than disulfide, a heme protein, NAD, NADP, a nitrogenous group, a quinone or similar compound or oxygen.


go_id: GO:0016665
term: obsolete oxidoreductase activity, acting on other nitrogenous compounds as donors, other acceptors
ontology: MF
definition:
OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces an acceptor other than a cytochrome, an iron-sulfur protein, oxygen, NAD or NADP.


go_id: GO:0016674
term: obsolete oxidoreductase activity, acting on sulfur group of donors, other acceptors
ontology: MF
definition:
OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces an acceptor other than quinone or a related compound, oxygen, NAD, NADP, an iron-sulfur protein, disulfide or a cytochrome.


go_id: GO:0016676
term: obsolete oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ontology: MF
definition:
OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a heme group acts as a hydrogen or electron donor and reduces oxygen.


go_id: GO:0016678
term: obsolete oxidoreductase activity, acting on heme group of donors, other acceptors
ontology: MF
definition:
OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a heme group acts as a hydrogen or electron donor and reduces an acceptor other than a nitrogenous group or oxygen.


go_id: GO:0016681
ontology: MF
term:
obsolete oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor

definition:
OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces a cytochrome.


go_id: GO:0016683
ontology: MF
term:
obsolete oxidoreductase activity, acting on diphenols and related substances as donors, other acceptors

definition:
OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces an acceptor other than a cytochrome, NAD, NADP or oxygen.


go_id: GO:0016700
term: obsolete oxidoreductase activity, acting on hydrogen as donor, other acceptors
ontology: MF
definition:
OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which hydrogen is the electron donor and reduces an acceptor other than a cytochrome, an iron-sulfur protein, NAD, NADP or a quinone or similar compound.


go_id: GO:0016704
ontology: MF
term:
obsolete oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, miscellaneous

definition:
OBSOLETE. A grouping term for oxidoreductases acting on single donors with incorporation of molecular oxygen that cannot be more accurated categorized.


go_id: GO:0016718
ontology: MF
term:
obsolete oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, miscellaneous

definition:
OBSOLETE. A grouping term for oxidoreductases, acting on paired donors with incorporation or reduction of molecular oxygen, that cannot be more accurately categorized.


go_id: GO:0016729
term: obsolete oxidoreductase activity, acting on CH2 groups, other acceptors
ontology: MF
definition:
OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces an acceptor other than disulfide, NAD, NADP or oxygen.


go_id: GO:0016733
term: obsolete iron-iron nitrogenase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: 8 reduced ferredoxin + 8 H+ + N2 + 16 ATP = 8 oxidized ferredoxin + 2 NH3 + 16 ADP + 16 phosphate.


go_id: GO:0016735
term: obsolete vanadium-iron nitrogenase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: 8 reduced ferredoxin + 8 H+ + nitrogen + 16 ATP = 8 oxidized ferredoxin + 2 NH3 + 16 ADP + 16 phosphate.


go_id: GO:0016764
term: obsolete transferase activity, transferring other glycosyl groups
ontology: MF
definition:
OBSOLETE. Catalysis of the transfer of a glycosyl group, other than hexosyl or pentosyl, from one compound (donor) to another (acceptor).


go_id: GO:0016771
term: obsolete transferase activity, transferring other nitrogenous groups
ontology: MF
definition:
OBSOLETE. Catalysis of the transfer of a nitrogenous group, other than amino, amidino or oxime, from one compound (donor) to another (acceptor).


go_id: GO:0016816
term: obsolete hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in other compounds
ontology: MF
definition:
OBSOLETE. Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in substances other than amides, amidines and nitriles.


go_id: GO:0016821
ontology: MF
definition: OBSOLETE. (Was not defined before being made obsolete).
term:
obsolete hydrolase activity, acting on acid anhydrides, involved in cellular and subcellular movement


go_id: GO:0016839
term: obsolete other carbon-oxygen lyase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the cleavage of a carbon-oxygen bond. Enzymes with this activity are 'miscellaneous' carbon-oxygen lyases that cannot be grouped into one of the specific subclasses of the carbon-oxygen lyases.


go_id: GO:0016845
term: obsolete other carbon-nitrogen lyase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the cleavage of a carbon-nitrogen bond. Enzymes with this activity are 'miscellaneous' carbon-nitrogen lyases that cannot be grouped into one of the specific subclasses of the carbon-nitrogen lyases.


go_id: GO:0016858
term: obsolete racemase and epimerase activity, acting on other compounds
ontology: MF
definition:
OBSOLETE. Racemase and epimerase activity on compounds other than amino acids, hydroxy acids, carbohydrates or their derivatives.


go_id: GO:0016865
term: obsolete intramolecular oxidoreductase activity, other intramolecular oxidoreductases
ontology: MF
definition:
OBSOLETE. A grouping term for intramolecular oxidoreductases that cannot be more accurately categorized.


go_id: GO:0016870
term: obsolete intramolecular transferase activity, transferring other groups
ontology: MF
definition:
OBSOLETE. A grouping term for intramolecular transferases that cannot be more accurately categorized.


go_id: GO:0016902
term: obsolete oxidoreductase activity, acting on the CH-OH group of donors, other acceptors
ontology: MF
definition:
OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces an acceptor other than a cytochrome, disulfide, NAD, NADP, oxygen or a quinone or similar compound.


go_id: GO:0016915
term: obsolete activin
ontology: MF
definition:
OBSOLETE. A nonsteroidal regulator, composed of two covalently linked beta subunits, that is synthesized in the pituitary gland and gonads and stimulates the secretion of follicle-stimulating hormone.


go_id: GO:0016916
term: obsolete inhibin
ontology: MF
definition:
OBSOLETE. Either of two glycoproteins (designated A and B), secreted by the gonads and present in seminal plasma and follicular fluid, that inhibit pituitary production of follicle-stimulating hormone.


go_id: GO:0016919
term: obsolete nardilysin activity
ontology: MF
definition:
OBSOLETE. Catalysis of the hydrolysis of polypeptides, preferably at the first bond of Xaa-Arg-Lys, and less commonly at the first bond of Arg-Arg-Xaa, in which Xaa is not Arg or Lys.


go_id: GO:0016921
term: obsolete pyroglutamyl-peptidase II activity
ontology: MF
definition:
OBSOLETE. Catalysis of the release of the N-terminal pyroglutamyl group from pGlu-His-Xaa tripeptides and pGlu-His-Xaa-Gly tetrapeptides.


go_id: GO:0016943
term: obsolete RNA polymerase I transcription elongation factor activity
ontology: MF
definition:
OBSOLETE. Any activity that modulates the rate of transcription elongation, the addition of ribonucleotides to an RNA molecule catalyzed by RNA polymerase I following transcription initiation.


go_id: GO:0016944
term: obsolete RNA polymerase II transcription elongation factor activity
ontology: MF
definition:
OBSOLETE. Any activity that modulates the rate of transcription elongation, the addition of ribonucleotides to an RNA molecule catalyzed by RNA polymerase II following transcription initiation.


go_id: GO:0016945
term: obsolete RNA polymerase III transcription elongation factor activity
ontology: MF
definition:
OBSOLETE. Any activity that modulates the rate of transcription elongation, the addition of ribonucleotides to an RNA molecule catalyzed by RNA polymerase III following transcription initiation.


go_id: GO:0016946
term: obsolete cathepsin F activity
ontology: MF
definition:
OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Cleavage of substrates with Phe and Leu in P2.


go_id: GO:0016963
term: obsolete alpha-2 macroglobulin receptor-associated protein activity
ontology: MF
definition:
OBSOLETE. Interaction with the alpha-2 macroglobulin receptor and glycoprotein gp330 forming a complex with the alpha-2 macroglobulin receptor light and heavy chains.


go_id: GO:0016969
term: obsolete hemerythrin
ontology: MF
definition:
OBSOLETE. An oxygen carrier found in a few groups of invertebrates, e.g. sipunculid worms, certain molluscs, and crustaceans.


go_id: GO:0016975
term: obsolete alpha-2 macroglobulin
ontology: MF
definition:
OBSOLETE. Inhibition of proteinase by a mechanism involving a bait region which contains specific sites, cleavage of which induces a conformational change that results in trapping of the proteinase; following cleavage in the bait region a thiolester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase; subsequently epsilon-amino groups of the proteinase react with thiolester linkages in the inhibitor to form stable amide links; the entrapped proteinase can now only act on low molecular mass substrates.


go_id: GO:0016988
term: obsolete transcription initiation factor antagonist activity
ontology: MF
definition:
OBSOLETE. The function of binding to a transcription factor and stopping, preventing or reducing the rate of its transcriptional activity.


go_id: GO:0017026
term: obsolete procollagen C-endopeptidase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the cleavage of the C-terminal propeptide at Ala-Asp in type I and II procollagens and at Arg-Asp in type III.


go_id: GO:0017027
ontology: MF
definition: OBSOLETE. (Was not defined before being made obsolete).
term:
obsolete transmembrane receptor protein serine/threonine kinase receptor-associated protein activity


go_id: GO:0017028
term: obsolete protein stabilization activity
ontology: MF
definition:
OBSOLETE. Strengthening of a bond between proteins. Proteins are large molecules composed of one or more chains of amino acids. The amino acids are joined in a specific order by peptide bonds.


go_id: GO:0017039
term: obsolete dipeptidyl-peptidase III activity
ontology: MF
definition:
OBSOLETE. Catalysis of the release of an N-terminal dipeptide from a peptide comprising four or more residues, with broad specificity; also acts on dipeptidyl 2-naphthylamides.


go_id: GO:0017043
term: obsolete adrenocorticotropin
ontology: MF
definition:
OBSOLETE. A polypeptide hormone which stimulates the adrenal cortex to synthesize and secrete glucocorticoid hormones.


go_id: GO:0017063
term: obsolete phosphatidylserine-specific phospholipase A1 activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: phosphatidylcholine + H2O = 2-acylglycerophosphocholine + a fatty acid anion.


go_id: GO:0017072
term: obsolete tubulin-specific chaperone activity
ontology: MF
definition:
OBSOLETE. Assists in the correct, non-covalent assembly of tubulin-containing structures in vivo, but is not a component of the assembled structures when performing its normal biological function.


go_id: GO:0017074
term: obsolete procollagen N-endopeptidase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the cleavage of the N-propeptide of collagen chain alpha-1(I) at Pro-Gln and of alpha-1(II) and alpha-2(I) chains at Ala-Gln.


go_id: GO:0017082
term: obsolete mineralocorticoid receptor activity
ontology: MF
definition:
OBSOLETE. Combining with a mineralocorticoid and transmitting the signal to the transcriptional machinery by binding to a specific DNA sequence in order to modulate transcription by RNA polymerase II.


go_id: GO:0017088
term: obsolete X-Pro dipeptidyl-peptidase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the hydrolysis of the terminal bond of Xaa-Pro-Xaa motifs to release unblocked, N-terminal dipeptides from substrates including Ala-Pro-para-nitroanilide and (sequentially, at the second, fourth and sixth bonds) of the motif Tyr-Pro-Phe-Pro-Gly-Pro-Ile.


go_id: GO:0017092
term: obsolete sterol regulatory element-binding protein site 2 protease activity
ontology: MF
definition:
OBSOLETE. Catalysis of the cleavage, within the membrane-spanning helix, of the amino-terminal half (the intermediate form) of sterol regulatory element binding protein (SREBP). This activity releases the transcription factor domain of SREBP from the membrane, freeing it to enter the nucleus.


go_id: GO:0017093
term: obsolete sterol regulatory element-binding protein protease activity
ontology: MF
definition:
OBSOLETE. Catalysis of the hydrolysis of peptide bonds within a sterol regulatory element binding protein (SREBP). SREBPs are transcription factors that bind sterol regulatory elements (SREs), DNA motifs found in the promoters of target genes.


go_id: GO:0017094
term: obsolete sterol regulatory element-binding protein site 1 protease activity
ontology: MF
definition:
OBSOLETE. Catalysis of the cleavage of a Leu-Ser bond within the luminal loop of a sterol regulatory element binding protein (SREBP). This activity is the first of two sequential cleavage reactions and cleaves SREBP into two membrane-bound halves.


go_id: GO:0017106
term: obsolete activin inhibitor activity
ontology: MF
definition:
OBSOLETE. Acts to negatively regulate the activity of activin, a nonsteroidal regulator synthesized in the pituitary gland and gonads that stimulates the secretion of follicle-stimulating hormone.


go_id: GO:0017107
term: obsolete anion exchanger adaptor activity
ontology: MF
definition:
OBSOLETE. The binding activity of a molecule that brings together an anion exchanger and one or more other molecules, permitting them to function in a coordinated way.


go_id: GO:0017114
term: obsolete wide-spectrum protease inhibitor activity
ontology: MF
definition:
OBSOLETE. Stops, prevents or reduces the activity of a protease by a wide-spectrum protease inhibitor. A wide-spectrum protease inhibitor is a protein having a peptide stretch which contains specific cleavage sites for different proteinases enabling inhibition of all four classes of proteinases by formation of a covalent bond between the inhibitor and the protease.


go_id: GO:0017120
term: obsolete polyphosphatidylinositol phosphatase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the conversion of phosphatidylinositol-3-phosphate, phosphatidylinositol-4-phosphate, and phosphatidylinositol-3,5-bisphosphate, but not PI-4,5-bisphosphate, to phosphatidylinositol; PPIPase activity is a key regulator of membrane trafficking and actin cytoskeleton organization.


go_id: GO:0017135
term: obsolete membrane-associated protein with guanylate kinase activity interacting
ontology: MF
definition:
OBSOLETE. The interaction with synapse-associated membrane-associated protein with guanylate kinase activity.


go_id: GO:0017163
term: obsolete basal transcription repressor activity
ontology: MF
definition:
OBSOLETE. Any transcription regulator activity that prevents or downregulates basal transcription. Basal transcription results from transcription that is controlled by the minimal complement of proteins necessary to reconstitute transcription from a minimal promoter.


go_id: GO:0017165
term: obsolete dipeptidase E activity
ontology: MF
definition:
OBSOLETE. Catalysis of the hydrolysis of dipeptides Asp-Xaa; does not act on peptides with N-terminal Glu, Asn or Gln, nor does it cleave isoaspartyl peptides.


go_id: GO:0017175
term: obsolete IMP-GMP specific 5'-nucleotidase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the conversion of 5'-ribonucleotides to ribonucleosides and phosphate, with specificity for IMP or GMP 5'-ribonucleotides and H2O as a nucleophile.


go_id: GO:0018033
term: obsolete protein C-terminal amidation
ontology: BP
definition:
OBSOLETE. The formation of a C-terminal amide by hydrolysis and oxidation of an interior peptide in a secreted protein.


go_id: GO:0018034
term: obsolete C-terminal peptidyl-alanine amidation
ontology: BP
definition:
OBSOLETE. The formation of a C-terminal peptidyl-alanine amide by hydrolysis and oxidation of an interior Ala-Gly peptide in a secreted protein.


go_id: GO:0018035
term: obsolete C-terminal peptidyl-arginine amidation
ontology: BP
definition:
OBSOLETE. The formation of a C-terminal peptidyl-arginine amide by hydrolysis and oxidation of an interior Arg-Gly peptide in a secreted protein.


go_id: GO:0018036
term: obsolete C-terminal peptidyl-asparagine amidation
ontology: BP
definition:
OBSOLETE. The formation of a C-terminal peptidyl-asparagine amide by hydrolysis and oxidation of an interior Asn-Gly peptide in a secreted protein.


go_id: GO:0018037
term: obsolete C-terminal peptidyl-aspartic acid amidation
ontology: BP
definition:
OBSOLETE. The formation of a C-terminal peptidyl-aspartic acid 1-amide by hydrolysis and oxidation of an interior Asp-Gly peptide in a secreted protein.


go_id: GO:0018038
term: obsolete C-terminal peptidyl-cysteine amidation
ontology: BP
definition:
OBSOLETE. The formation of a C-terminal peptidyl-cysteine amide by hydrolysis and oxidation of an interior Cys-Gly peptide in a secreted protein.


go_id: GO:0018039
term: obsolete C-terminal peptidyl-glutamine amidation
ontology: BP
definition:
OBSOLETE. The formation of a C-terminal peptidyl-glutamine amide by hydrolysis and oxidation of an interior Gln-Gly peptide in a secreted protein.


go_id: GO:0018040
term: obsolete C-terminal peptidyl-glutamic acid amidation
ontology: BP
definition:
OBSOLETE. The formation of a C-terminal peptidyl-glutamic acid amide by hydrolysis and oxidation of an interior Glu-Gly peptide in a secreted protein.


go_id: GO:0018041
term: obsolete C-terminal peptidyl-glycine amidation
ontology: BP
definition:
OBSOLETE. The formation of a C-terminal peptidyl-glycine acid amide by hydrolysis and oxidation of an interior Gly-Gly peptide in a secreted protein.


go_id: GO:0018042
term: obsolete C-terminal peptidyl-histidine amidation
ontology: BP
definition:
OBSOLETE. The formation of a C-terminal peptidyl-histidine amide by hydrolysis and oxidation of an interior His-Gly peptide in a secreted protein.


go_id: GO:0018043
term: obsolete C-terminal peptidyl-isoleucine amidation
ontology: BP
definition:
OBSOLETE. The formation of a C-terminal peptidyl-isoleucine amide by hydrolysis and oxidation of an interior Ile-Gly peptide in a secreted protein.


go_id: GO:0018044
term: obsolete C-terminal peptidyl-leucine amidation
ontology: BP
definition:
OBSOLETE. The formation of a C-terminal peptidyl-leucine amide by hydrolysis and oxidation of an interior Leu-Gly peptide in a secreted protein.


go_id: GO:0018045
term: obsolete C-terminal peptidyl-lysine amidation
ontology: BP
definition:
OBSOLETE. The formation of a C-terminal peptidyl-lysine amide by hydrolysis and oxidation of an interior Lys-Gly peptide in a secreted protein.


go_id: GO:0018046
term: obsolete C-terminal peptidyl-methionine amidation
ontology: BP
definition:
OBSOLETE. The formation of a C-terminal peptidyl-methionine amide by hydrolysis and oxidation of an interior Met-Gly peptide in a secreted protein.


go_id: GO:0018047
term: obsolete C-terminal peptidyl-phenylalanine amidation
ontology: BP
definition:
OBSOLETE. The formation of a C-terminal peptidyl-phenylalanine amide by hydrolysis and oxidation of an interior Phe-Gly peptide in a secreted protein.


go_id: GO:0018048
term: obsolete C-terminal peptidyl-proline amidation
ontology: BP
definition:
OBSOLETE. The formation of a C-terminal peptidyl-proline amide by hydrolysis and oxidation of an interior Pro-Gly peptide in a secreted protein.


go_id: GO:0018049
term: obsolete C-terminal peptidyl-serine amidation
ontology: BP
definition:
OBSOLETE. The formation of a C-terminal peptidyl-serine amide by hydrolysis and oxidation of an interior Ser-Gly peptide in a secreted protein.


go_id: GO:0018050
term: obsolete C-terminal peptidyl-threonine amidation
ontology: BP
definition:
OBSOLETE. The formation of a C-terminal peptidyl-threonine amide by hydrolysis and oxidation of an interior Thr-Gly peptide in a secreted protein.


go_id: GO:0018051
term: obsolete C-terminal peptidyl-tryptophan amidation
ontology: BP
definition:
OBSOLETE. The formation of a C-terminal peptidyl-tryptophan amide by hydrolysis and oxidation of an interior Trp-Gly peptide in a secreted protein.


go_id: GO:0018052
term: obsolete C-terminal peptidyl-tyrosine amidation
ontology: BP
definition:
OBSOLETE. The formation of a C-terminal peptidyl-tyrosine amide by hydrolysis and oxidation of an interior Tyr-Gly peptide in a secreted protein.


go_id: GO:0018053
term: obsolete C-terminal peptidyl-valine amidation
ontology: BP
definition:
OBSOLETE. The formation of a C-terminal peptidyl-valine amide by hydrolysis and oxidation of an interior Val-Gly peptide in a secreted protein.


go_id: GO:0018054
term: obsolete peptidyl-lysine biotinylation
ontology: BP
definition:
OBSOLETE. The covalent modification of peptidyl-lysine by biotin to form peptidyl-N6-biotinyl-L-lysine.


go_id: GO:0018074
term: obsolete peptidyl-histidine bromination
ontology: BP
definition:
OBSOLETE. The bromination of peptidyl-histidine to form peptidyl-L-bromohistidine; the position of the bromine substitution is unknown.


go_id: GO:0018166
term: obsolete C-terminal protein-tyrosinylation
ontology: BP
definition:
OBSOLETE. The ATP-dependent addition of a tyrosine residue to the C-terminus of a protein; typically the addition of tyrosine to the C-terminus of detyrosinated alpha-tubulin by the enzyme tubulin-tyrosine ligase.


go_id: GO:0018170
term: obsolete C-terminal peptidyl-polyglutamic acid amidation
ontology: BP
definition:
OBSOLETE. The formation of a C-terminal peptidyl-polyglutamic acid to form a peptidyl-N-L-glutamyl-poly-L-glutamic acid C-terminus.


go_id: GO:0018179
term: obsolete peptidyl-cysteine desulfurization
ontology: BP
definition:
OBSOLETE. The desulfurization of peptidyl-L-cysteine to yield L-alanine and elemental sulfur; peptidyl-L-cysteine persulfide is an intermediate.


go_id: GO:0018192
term: obsolete enzyme active site formation via cysteine modification to L-cysteine persulfide
ontology: BP
definition:
OBSOLETE. The formation of an enzyme active site via modification of peptidyl-cysteine to peptidyl-L-cysteine persulfide.


go_id: GO:0018248
term: obsolete enzyme active site formation via peptidyl cysteine sulfation
ontology: BP
definition:
OBSOLETE. The formation of an enzyme active site via transient sulfation of peptidyl-cysteine to form S-sulfo-L-cysteine.


go_id: GO:0018252
term: obsolete peptide cross-linking via L-seryl-5-imidazolinone glycine
ontology: BP
definition:
OBSOLETE. The formation of the green fluorescent protein chromophore cross-link from the alpha-carboxyl carbon of residue n, a serine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons.


go_id: GO:0018286
term: obsolete iron incorporation into iron-sulfur cluster via hexakis-L-cysteinyl triiron trisulfide
ontology: BP
definition:
OBSOLETE. The incorporation of iron into a 3Fe-3S iron-sulfur cluster via hexakis-L-cysteinyl triiron trisulfide. The three-iron three-sulfur cluster probably does not exist except as an intermediate form.


go_id: GO:0018300
term: obsolete iron incorporation into iron-sulfur cluster via hexakis-L-cysteinyl hexairon hexasulfide
ontology: BP
definition:
OBSOLETE. The incorporation of iron into a 6Fe-6S cluster by hexakis-L-cysteinyl hexairon hexasulfide.


go_id: GO:0018308
term: obsolete enzyme active site formation via N6-pyruvic acid 2-iminyl-L-lysine
ontology: BP
definition:
OBSOLETE. The transient modification of lysine by pyruvate to form N6-pyruvic acid 2-iminyl-L-lysine, found in the active site of dihydrodipicolinate synthase.


go_id: GO:0018314
term: obsolete protein-pyrroloquinoline-quinone linkage
ontology: BP
definition:
OBSOLETE. The covalent cross-linking of pyrroloquinoline-quinone to peptidyl-glutamic acid and peptidyl-tyrosine.


go_id: GO:0018324
term: obsolete enzyme active site formation via L-cysteine sulfenic acid
ontology: BP
definition:
OBSOLETE. The oxidation of peptidyl-cysteine to form peptidyl-L-cysteine sulfenic acid, found in the active site of NADH peroxidase, nitrile hydratase, and peptide methionine sulfoxide reductase.


go_id: GO:0018327
term: obsolete enzyme active site formation via 1'-phospho-L-histidine
ontology: BP
definition:
OBSOLETE. The transient phosphorylation of peptidyl-histidine to form 1'-phospho-L-histidine (otherwise known as tau-phosphohistidine, tele-phosphohistidine).


go_id: GO:0018328
term: obsolete enzyme active site formation via 3'-phospho-L-histidine
ontology: BP
definition:
OBSOLETE. The transient phosphorylation of peptidyl-histidine to form 3'-phospho-L-histidine (otherwise known as pi-phosphohistidine, pros-phosphohistidine).


go_id: GO:0018329
term: obsolete enzyme active site formation via N6-(phospho-5'-adenosine)-L-lysine
ontology: BP
definition:
OBSOLETE. The transient adenylylation of lysine to form N6-(phospho-5'-adenosine)-L-lysine, found in the active site of DNA ligase and RNA ligase.


go_id: GO:0018330
term: obsolete enzyme active site formation via N6-(phospho-5'-guanosine)-L-lysine
ontology: BP
definition:
OBSOLETE. The transient guanylylation of lysine to form N6-(phospho-5'-guanosine)-L-lysine, found in the guanylyltransferase active site of mRNA capping enzyme.


go_id: GO:0018332
term: obsolete enzyme active site formation via O-(phospho-5'-adenosine)-L-threonine
ontology: BP
definition:
OBSOLETE. The transient adenylylation of threonine to form N6-(phospho-5'-adenosine)-L-threonine, found in the active site of bovine phosphodiesterase I.


go_id: GO:0018391
term: obsolete C-terminal peptidyl-glutamic acid tyrosinylation
ontology: BP
definition:
OBSOLETE. The ATP-dependent addition of a tyrosine residue to a glutamic acid residue at the C-terminus of a protein.


go_id: GO:0018407
term: obsolete peptidyl-thyronine iodination to form 3',3'',5'-triiodo-L-thyronine
ontology: BP
definition:
OBSOLETE. The iodination of peptidyl-thyronine to form peptidyl-3',3'',5'-triiodo-L-thyronine (triiodothyronine).


go_id: GO:0018408
term: obsolete peptidyl-thyronine iodination to form 3',3'',5',5''-tetraiodo-L-thyronine
ontology: BP
definition:
OBSOLETE. The iodination of peptidyl-thyronine to form peptidyl-3',3'',5',5''-tetraiodo-L-thyronine (L-thyroxine).


go_id: GO:0018443
term: obsolete enzyme active site formation via L-aspartic 4-phosphoric anhydride
ontology: BP
definition:
OBSOLETE. The transient phosphorylation of peptidyl-aspartic acid to form L-aspartic 4-phosphoric anhydride.


go_id: GO:0018512
term: obsolete 1,6-dihydroxy-5-methylcyclohexa-2,4-dienecarboxylate dehydrogenase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: 1,6-dihydroxy-5-methylcyclohexa-2,4-dienecarboxylate + NAD+ = 3-methylcatechol + CO2 + NADH + H+.


go_id: GO:0018660
term: obsolete 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: 4-hydroxyphenylacetate + NADH + H+ + O2 = 3,4-dihydroxyphenylacetate + NAD+ + H2O.


go_id: GO:0018704
term: obsolete 5-chloro-2-hydroxymuconic semialdehyde dehalogenase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: 5-chloro-2-hydroxymuconic semialdehyde + H+ + 2 e- = Cl- + 2-hydroxymuconic semialdehyde.


go_id: GO:0018853
term: obsolete perillyl-CoA synthetase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: perillic acid + CoA-SH + ATP = H2O + ADP/AMP + mono/diphosphate + perillyl-CoA.


go_id: GO:0018988
term: obsolete molting cycle, protein-based cuticle
ontology: BP
definition:
OBSOLETE. The periodic shedding of part or all of a protein-based cuticle, which is then replaced by a new protein-based cuticle. A cuticle is the outer layer of an animal which acts to prevent water loss.


go_id: GO:0019017
term: obsolete segmented viral genome
ontology: CC
definition:
OBSOLETE. A viral genome that is divided into two or more physically separate molecules of nucleic acid and packaged into a single virion.


go_id: GO:0019018
term: obsolete bipartite viral genome
ontology: CC
definition:
OBSOLETE. A segmented viral genome consisting of two sub-genomic nucleic acids but each nucleic acid is packaged into a different virion.


go_id: GO:0019019
term: obsolete tripartite viral genome
ontology: CC
definition:
OBSOLETE. A segmented viral genome consisting of three sub-genomic nucleic acids but each nucleic acid is packaged into a different virion.


go_id: GO:0019020
term: obsolete multipartite viral genome
ontology: CC
definition:
OBSOLETE. A segmented viral genome consisting of more than three sub-genomic nucleic acids but each nucleic acid is packaged into a different virion.


go_id: GO:0019022
term: obsolete RNA viral genome
ontology: CC
definition:
OBSOLETE. A viral genome composed of ribonucleic acid. This results in genome replication and expression of genetic information being inextricably linked.


go_id: GO:0019027
term: obsolete ambisense viral genome
ontology: CC
definition:
OBSOLETE. A RNA genome that contains coding regions that are either positive sense or negative sense on the same RNA molecule.


go_id: GO:0019038
term: obsolete provirus
ontology: CC
definition:
OBSOLETE. The name given to a viral genome after it has been integrated into the host genome; particularly applies to retroviruses and is a required part of the retroviral replication cycle.


go_id: GO:0019078
term: obsolete lytic viral budding
ontology: BP
definition:
OBSOLETE. A form of viral release in which the viral particles bud out through cellular membranes, resulting in cell lysis. It is also a form of viral envelopment.


go_id: GO:0019105
term: obsolete N-palmitoyltransferase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the transfer of a palmitoyl group to a nitrogen atom on the acceptor molecule.


go_id: GO:0019131
term: obsolete tripeptidyl-peptidase I activity
ontology: MF
definition:
OBSOLETE. Catalysis of the release of an N-terminal tripeptide from a polypeptide; requires acid pH.


go_id: GO:0019132
term: obsolete C-terminal processing peptidase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the cleavage of peptides after specific recognition of a C-terminal tripeptide, Xaa-Yaa-Zaa, in which Xaa is preferably Ala or Leu, Yaa is preferably Ala or Tyr, and Zaa is preferably Ala. Cleavage is at a variable distance from the C-terminus; a typical cleavage is -Ala-Ala-Arg-Ala-Ala-Lys-Glu-Asn-Tyr-Ala-Leu-Ala-Ala.


go_id: GO:0019268
term: obsolete glutamate biosynthetic process, using glutamate dehydrogenase (NAD(P)+)
ontology: BP
definition:
OBSOLETE. The chemical reactions and pathways resulting in the formation of glutamate, catalyzed by the enzyme glutamate dehydrogenase (NADP+).


go_id: GO:0019269
term: obsolete glutamate biosynthetic process, using glutamate synthase (NADPH)
ontology: BP
definition:
OBSOLETE. The chemical reactions and pathways resulting in the formation of glutamate, catalyzed by the enzyme glutamate synthase (NADPH).


go_id: GO:0019443
term: obsolete tryptophan catabolic process, using tryptophanase
ontology: BP
definition:
OBSOLETE. The chemical reactions and pathways resulting in the breakdown of tryptophan, catalyzed by the enzyme tryptophanase (EC:4.1.99.1).


go_id: GO:0019446
term: obsolete tyrosine catabolic process to phosphoenolpyruvate
ontology: BP
definition:
OBSOLETE. The chemical reactions and pathways resulting in the breakdown of tyrosine into other compounds, including phosphoenolpyruvate.


go_id: GO:0019562
term: obsolete L-phenylalanine catabolic process to phosphoenolpyruvate
ontology: BP
definition:
OBSOLETE. The chemical reactions and pathways resulting in the breakdown of L-phenylalanine into other compounds, including phosphoenolpyruvate.


go_id: GO:0019575
term: obsolete sucrose catabolic process, using beta-fructofuranosidase
ontology: BP
definition:
OBSOLETE. The chemical reactions and pathways resulting in the breakdown of sucrose, catalyzed by the enzyme beta-fructofuranosidase (EC:3.2.1.26).


go_id: GO:0019675
term: obsolete NAD phosphorylation and dephosphorylation
ontology: BP
definition:
OBSOLETE. The addition or removal of a phosphate group from nicotinamide adenine dinucleotide (NAD), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid.


go_id: GO:0019717
term: obsolete synaptosome
ontology: CC
definition:
OBSOLETE. Any of the discrete particles (nerve-ending particles) formed from the clublike presynaptic nerve endings that resist disruption and are snapped or torn off their attachments when brain tissue is homogenized in media isosmotic to plasma.


go_id: GO:0019718
term: obsolete rough microsome
ontology: CC
definition:
OBSOLETE. Vesicular particles formed from disrupted endoplasmic reticulum membranes and studded with ribosomes on the outside.


go_id: GO:0019719
term: obsolete smooth microsome
ontology: CC
definition:
OBSOLETE. Vesicular particles formed from disrupted endoplasmic reticulum and plasma membranes without any adhering ribosomes.


go_id: GO:0019729
term: obsolete peptide cross-linking via 2-imino-glutaminyl-5-imidazolinone glycine
ontology: BP
definition:
OBSOLETE. The formation of the fluorescent protein FP583 chromophore cross-link from the alpha-carboxyl carbon of residue n, a glutamine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons.


go_id: GO:0019793
term: obsolete ISG15 carrier activity
ontology: MF
definition:
OBSOLETE. Catalysis of the transfer of ISG15 (interferon-stimulated gene-15) from one side of the membrane to the other.


go_id: GO:0019794
term: obsolete nonprotein amino acid metabolic process
ontology: BP
definition:
OBSOLETE. The chemical reactions and pathways involving any amino acid not found, or rarely found, in peptide linkage in proteins.


go_id: GO:0019795
term: obsolete nonprotein amino acid biosynthetic process
ontology: BP
definition:
OBSOLETE. The chemical reactions and pathways resulting in the formation of any amino acid that does not normally occur as a constituent residue of proteins.


go_id: GO:0019796
term: obsolete nonprotein amino acid catabolic process
ontology: BP
definition:
OBSOLETE. The chemical reactions and pathways resulting in the breakdown of any amino acid not found, or rarely found, in peptide linkage in proteins.


go_id: GO:0019804
term: obsolete quinolinate synthetase complex
ontology: CC
definition:
OBSOLETE. A heterodimer which acts as a quinolinate synthetase; quinolinate synthetase B (L-aspartate oxidase) catalyzes the oxidation of L-aspartate to L-iminoaspartate; quinolinate synthetase A condenses L-imidoaspartate and dihydroxyacetone to quinolinate.


go_id: GO:0019833
term: obsolete ice nucleation activity
ontology: MF
definition:
OBSOLETE. Catalysis of the formation of ice crystals in extracellular fluid at relatively high temperatures (up to -2 degrees C) to protect the organism from damage by intracellular ice formation. Ice nucleation proteins function by binding an ice crystal and then encouraging it to form larger crystals. Ice nucleation is a chemical process but these proteins can positively regulate it. There are two different uses of ice nucleation proteins: bacteria secrete them extracellularly to cause a host organism's cells to freeze and die, and fish use them to protect themselves from intracellular ice formation.


go_id: GO:0019844
term: obsolete endotoxin activity
ontology: MF
definition:
OBSOLETE. The function of any microbial toxin that cannot be easily separated from the structure of the cell.


go_id: GO:0019845
term: obsolete exotoxin activity
ontology: MF
definition:
OBSOLETE. The function of a toxin formed by a microorganism and secreted into the surrounding medium.


go_id: GO:0019848
term: obsolete conotoxin activity
ontology: MF
definition:
OBSOLETE. Acts to inhibit neural function in another organism by inhibiting voltage-gated calcium ion channels and neurotransmitter release. This function is thought to be specific to the venom of two marine snail species.


go_id: GO:0019895
term: obsolete kinesin-associated mitochondrial adaptor activity
ontology: MF
definition:
OBSOLETE. The activity of linking kinesins, cytoplasmic proteins responsible for moving vesicles and organelles towards the distal end of microtubules, to mitochondria.


go_id: GO:0019923
term: obsolete alpha-1-microglobulin-chromophore linkage
ontology: BP
definition:
OBSOLETE. The covalent linking of the alpha-1-microglobulin chromophore to the protein; the structure of the chromophore is not known. It is probably heterogeneous and involving two cysteines in thioether bonds.


go_id: GO:0019942
term: obsolete NEDD8 class-dependent protein catabolic process
ontology: BP
definition:
OBSOLETE. The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by covalent attachment of the ubiquitin-like protein NEDD8 (RUB1) to the target protein.


go_id: GO:0019946
term: obsolete SMT3-dependent protein catabolic process
ontology: BP
definition:
OBSOLETE. The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by covalent attachment of the ubiquitin-like protein SMT3 to the target protein.


go_id: GO:0019987
term: obsolete negative regulation of anti-apoptosis
ontology: BP
definition:
OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of anti-apoptosis.


go_id: GO:0021777
term: obsolete BMP signaling pathway involved in spinal cord association neuron specification
ontology: BP
definition:
OBSOLETE. The series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to its commitment to an association neuron fate.


go_id: GO:0021865
term: obsolete symmetric radial glial cell division in forebrain
ontology: BP
definition:
OBSOLETE. The mitotic division of a radial glial cell giving rise to two new radial glial cells in the forebrain.


go_id: GO:0021866
term: obsolete asymmetric radial glial cell division in forebrain
ontology: BP
definition:
OBSOLETE. The mitotic cell division of a radial glial cell giving rise to a radial glial cell and another cell type.


go_id: GO:0021867
term: obsolete neuron-producing asymmetric radial glial cell division in forebrain
ontology: BP
definition:
OBSOLETE. The unequal mitotic division of a radial glial cell in the forebrain that gives rise to a radial glial cell and a post-mitotic neuronal progenitor.


go_id: GO:0021868
term: obsolete ventricular zone cell-producing asymmetric radial glial cell division in forebrain
ontology: BP
definition:
OBSOLETE. The unequal mitotic division of a forebrain radial glial cell that gives rise to a radial glial cell and a ventricular zone cell.


go_id: GO:0021882
ontology: BP
term:
obsolete regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment

definition:
OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain.


go_id: GO:0021883
term: obsolete cell cycle arrest of committed forebrain neuronal progenitor cell
ontology: BP
definition:
OBSOLETE. The process in which the cell cycle is halted during one of the normal phases (G1, S, G2, M) in a cell that has been committed to become a neuron that will reside in the forebrain.


go_id: GO:0021909
ontology: BP
term:
obsolete regulation of transcription from RNA polymerase II promoter involved in spinal cord anterior-posterior patterning

definition:
OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that results in the spatial identity of regions along the anterior-posterior axis of the spinal cord.


go_id: GO:0021912
ontology: BP
term:
obsolete regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification

definition:
OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that results the commitment of a cell to become a motor neuron in the ventral spinal cord.


go_id: GO:0021913
ontology: BP
term:
obsolete regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification

definition:
OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that results in the commitment of a cell to become an interneuron in the ventral spinal cord.


go_id: GO:0021918
ontology: BP
term:
obsolete regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment

definition:
OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of spinal cord motor neurons to specific motor neuron types along the anterior-posterior axis.


go_id: GO:0021920
ontology: BP
term:
obsolete regulation of transcription from RNA polymerase II promoter involved in spinal cord association neuron specification

definition:
OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of neuronal precursors to association neurons in the dorsal spinal cord.


go_id: GO:0022014
term: obsolete radial glial cell division in subpallium
ontology: BP
definition:
OBSOLETE. The division of a radial glial cell in the subpallium. A radial glial cell is a precursor cell that gives rise to neurons and astrocytes.


go_id: GO:0022610
term: obsolete biological adhesion
ontology: BP
definition:
OBSOLETE. The attachment of a cell or organism to a substrate, another cell, or other organism. Biological adhesion includes intracellular attachment between membrane regions.


go_id: GO:0022815
term: obsolete large uncharged polar molecule transmembrane transporter activity
ontology: MF
definition:
OBSOLETE. Catalysis of the transfer of a large uncharged polar molecule from one side of a membrane to the other.


go_id: GO:0022854
term: obsolete active large uncharged polar molecule transmembrane transporter activity
ontology: MF
definition:
OBSOLETE. Catalysis of the transfer of a large uncharged polar molecule from one side of the membrane to the other, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction.


go_id: GO:0022865
term: obsolete transmembrane electron transfer carrier
ontology: MF
definition:
OBSOLETE. Enables electron flow across a biological membrane, from donors localized on one side of the membrane to acceptors localized on the other side. These systems contribute to or subtract from the membrane potential, depending on the direction of electron flow. They are therefore important to cellular energetics.


go_id: GO:0023004
term: obsolete activation of dopamine receptor signaling pathway
ontology: BP
definition:
OBSOLETE. Any process that initiates the dopamine receptor protein signaling pathway through stimulation of the dopamine receptor.


go_id: GO:0023010
term: obsolete regulation of initiation of T cell receptor signaling
ontology: BP
definition:
OBSOLETE. Any process that modulates the frequency, rate or extent of the initiation of T cell receptor signaling.


go_id: GO:0023011
term: obsolete positive regulation of initiation of T cell receptor signaling
ontology: BP
definition:
OBSOLETE. Any process that activates, maintains or increases the frequency, rate or extent of the initiation of T cell receptor signaling.


go_id: GO:0023012
term: obsolete initiation of T cell receptor signaling by binding of a MHC complex to T cell receptor
ontology: BP
definition:
OBSOLETE. The process in which binding of an MHC complex to T cell receptor causes activation of T cell receptor signaling.


go_id: GO:0023018
term: obsolete T cell activation of signal transmission via diffusible molecule
ontology: BP
definition:
OBSOLETE. The process in which signal transmission via a diffusible molecule is initiated by a T cell.


go_id: GO:0023020
term: obsolete regulation of gene expression as a consequence of T cell signal transmission
ontology: BP
definition:
OBSOLETE. Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a T cell signal is released and/or conveyed from one location to another.


go_id: GO:0023036
term: obsolete initiation of signal transduction
ontology: BP
definition:
OBSOLETE. The process in which a signal causes activation of a receptor, for example, via a conformation change.


go_id: GO:0023040
term: obsolete signaling via ionic flux
ontology: BP
definition:
OBSOLETE. The process in which information is sent from one location to another, within a living organism or between living organisms, via ionic flux.


go_id: GO:0023042
term: obsolete signaling via protein/peptide mediator
ontology: BP
definition:
OBSOLETE. The process in which information is sent from one location to another, within a living organism or between living organisms, via a protein/peptide mediator.


go_id: GO:0023043
term: obsolete signaling via lipid mediator
ontology: BP
definition:
OBSOLETE. The process in which information is sent from one location to another, within a living organism or between living organisms, via a lipid mediator.


go_id: GO:0023044
term: obsolete signaling via chemical mediator
ontology: BP
definition:
OBSOLETE. The process in which information is sent from one location to another, within a living organism or between living organisms, via a chemical mediator.


go_id: GO:0023050
term: obsolete consequence of signal transmission
ontology: BP
definition:
OBSOLETE. The steps whereby the downstream processes started by a signal are brought to a conclusion. Examples include destruction of cAMP by PDE, or endocytosis resulting from receptor phosphorylation. The termination process ends when the receptor has returned to its inactive state.


go_id: GO:0023062
term: obsolete signal transmission via transcytosis
ontology: BP
definition:
OBSOLETE. The process in which a signal is conveyed via transcytosis. Transcytosis is the directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side.


go_id: GO:0030005
term: obsolete cellular di-, tri-valent inorganic cation homeostasis
ontology: BP
definition:
OBSOLETE. Any process involved in the maintenance of an internal steady state of divalent or trivalent cations at the level of a cell.


go_id: GO:0030006
term: obsolete heavy cellular metal ion homeostasis
ontology: BP
definition:
OBSOLETE. Regulation of the levels, transport, and metabolism of ions of a heavy metal, a metal that can form a coordination bond with a protein, as opposed to an alkali or alkaline-earth metal that can only form an ionic bond; this definition includes the following biologically relevant heavy metals: Cd, Co, Cu, Fe, Hg, Mn, Mo, Ni, V, W, Zn.


go_id: GO:0030019
term: obsolete tryptase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the preferential cleavage of Arg-Xaa, Lys-Xaa, but with more restricted specificity than trypsin.


go_id: GO:0030022
term: obsolete adhesive extracellular matrix constituent
ontology: MF
definition:
OBSOLETE. A constituent of the extracellular matrix that facilitates attachment of cells to the matrix.


go_id: GO:0030051
term: obsolete FK506-sensitive peptidyl-prolyl cis-trans isomerase
ontology: MF
definition:
OBSOLETE. Interacts selectively with the immunosuppressant FK506, and possesses peptidyl-prolyl isomerase activity (catalysis of the reaction: peptidoproline (omega=180) = peptidylproline (omega=0)).


go_id: GO:0030052
term: obsolete parvulin
ontology: MF
definition:
OBSOLETE. A peptidyl-prolyl isomerase isolated from Escherichia coli. It does not have any function as an immunophilin.


go_id: GO:0030053
term: obsolete immunophilin
ontology: MF
definition:
OBSOLETE. Any member of a family of receptors that includes the major FK506 binding protein FKBP and cyclophilin. These two proteins are unrelated in amino-acid sequence, but both possess peptidyl-prolyl isomerase activity which is blocked by immunosuppressants that block signal-transduction pathways leading to T cell activation such as FK506 and rapamycin, which block FKBP, or cyclosporin A, which blocks cyclophilin.


go_id: GO:0030063
term: obsolete murein sacculus
ontology: CC
definition:
OBSOLETE. A structure formed of the cross-linked polymer peptidoglycan (also called murein) that forms a covalently closed net around a bacterial cell, and imparts structural stability to the bacterial cell wall.


go_id: GO:0030074
term: obsolete thylakoid (sensu Proteobacteria)
ontology: CC
definition:
OBSOLETE. A thylakoid; as in, but not restricted to, the purple bacteria and relatives (Proteobacteria, ncbi_taxonomy_id:1224).


go_id: GO:0030105
term: obsolete anaphylaxis
ontology: BP
definition:
OBSOLETE. Extreme immunological sensitivity of the body or tissues to the reintroduction of an antigen. It is a form of anamnestic reaction and is accompanied by pathological changes in tissues or organs due to the release of pharmacologically active substances.


go_id: GO:0030106
term: obsolete MHC class I receptor activity
ontology: MF
definition:
OBSOLETE. A major histocompatibility complex class I receptor. These display processed antigens from the endocytosed bacteria. MHC class I proteins can form complexes with processed antigen peptides only if the antigen is synthesized in the same cell. As a consequence, T lymphocytes can only bind to class-I-positive cells that are synthesizing the antigen (e.g. virus-infected cells).


go_id: GO:0030161
term: obsolete calpain inhibitor activity
ontology: MF
definition:
OBSOLETE. Stops, prevents or reduces the activity of the enzyme calpain, which catalyzes of the preferential cleavage of Tyr-Xaa, Met-Xaa or Arg-Xaa with Leu or Val as the P2 residue.


go_id: GO:0030180
term: obsolete solute:solute exchange
ontology: BP
definition:
OBSOLETE. Exchange diffusion of two solutes between the inside and outside of a cell or subcellular compartment, in which movement of one solute down a concentration gradient drives movement of the other solute in the opposite direction.


go_id: GO:0030181
term: obsolete sodium:calcium exchange
ontology: BP
definition:
OBSOLETE. Exchange diffusion sodium and calcium ions in which influx of sodium ions to the cytosol drives the efflux of calcium ions from the cell.


go_id: GO:0030303
term: obsolete stromelysin 2 activity
ontology: MF
definition:
OBSOLETE. Catalysis of the cleavage of peptide bonds in collagen with preferential cleavage where P1', P2' and P3' are hydrophobic residues; action on collagen types III, IV and V is weak.


go_id: GO:0030319
term: obsolete cellular di-, tri-valent inorganic anion homeostasis
ontology: BP
definition:
OBSOLETE. Any process involved in the maintenance of an internal steady state of divalent or trivalent inorganic anions at the level of a cell.


go_id: GO:0030364
term: obsolete cleavage and polyadenylylation specificity factor activity
ontology: MF
definition:
OBSOLETE. A factor required in mRNA 3' end processing for both the cleavage and poly(A) addition reactions and, consistent with this function, recognizes AAUAAA, a signal also essential for both reactions.


go_id: GO:0030365
term: obsolete cleavage stimulation factor activity
ontology: MF
definition:
OBSOLETE. A factor is necessary for cleavage but not for poly(A) addition in mRNA 3' end processing; can stimulate poly(A) addition on substrates with a CstF binding site upstream of the AAUAAA hexanucleotide.


go_id: GO:0030400
term: obsolete protease substrate recruitment factor activity
ontology: MF
definition:
OBSOLETE. A recruiting factor or adaptor molecule associated with the proteasome that activates degradation of specific proteasomal substrates and links them to the degradation machinery; it is not involved in ubiquitination; does not possess proteolytic activity.


go_id: GO:0030401
term: obsolete transcription antiterminator activity
ontology: MF
definition:
OBSOLETE. Functions to prevent the termination of RNA synthesis. Acts as a regulatory device, e.g. in phage lambda, enabling a terminator to be masked from RNA polymerase so that distal genes can be expressed.


go_id: GO:0030484
term: obsolete muscle fiber
ontology: CC
definition:
OBSOLETE. The contractile fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle.


go_id: GO:0030528
term: obsolete transcription regulator activity
ontology: MF
definition:
OBSOLETE. Plays a role in regulating transcription; may bind a promoter or enhancer DNA sequence or interact with a DNA-binding transcription factor.


go_id: GO:0030530
term: obsolete heterogeneous nuclear ribonucleoprotein complex
ontology: CC
definition:
OBSOLETE. Particulate complex of heterogeneous nuclear RNA (hnRNA; a heterogeneous mixture of RNA molecules of high Mr with a rapid turnover rate that occurs in cell nuclei during protein synthesis; it is the form of RNA synthesized in eukaryotes by RNA polymerase II, that which is translated into protein) with protein, which is cell-specific and heterogeneous. The protein component may play a role in the processing of the hnRNA to mRNA.


go_id: GO:0030531
term: obsolete small cytoplasmic ribonucleoprotein complex
ontology: CC
definition:
OBSOLETE. A complex composed of RNA of the small cytoplasmic RNA (scRNA) class and protein, found in the cytoplasm.


go_id: GO:0030601
term: obsolete aminopeptidase B activity
ontology: MF
definition:
OBSOLETE. Catalysis of the release of N-terminal Arg and Lys from oligopeptides when P1' is not Pro. Also acts on arylamides of Arg and Lys.


go_id: GO:0030602
term: obsolete chymosin activity
ontology: MF
definition:
OBSOLETE. Catalysis of the lysis of peptide bonds with broad specificity similar to that of pepsin A. Clots milk by cleavage of a single Ser-Phe-l-Met-Ala bond in kappa-casein.


go_id: GO:0030616
term: obsolete transforming growth factor beta receptor, common-partner cytoplasmic mediator activity
ontology: MF
definition:
OBSOLETE. A TGF-beta cytoplasmic mediator that forms a complex with a phosphorylated pathway-specific mediator. The heterocomplex translocates to the nucleus to regulate transcription.


go_id: GO:0030617
term: obsolete transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity
ontology: MF
definition:
OBSOLETE. A TGF-beta cytoplasmic mediator that inhibits the signaling function of common-partner and pathway-specific mediators.


go_id: GO:0030618
term: obsolete transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
ontology: MF
definition:
OBSOLETE. A TGF-beta cytoplasmic mediator that is phosphorylated by a TGFbeta receptor and complexes with a common-partner mediator. The- heterocomplex translocates to the nucleus to regulate transcription.


go_id: GO:0030636
term: obsolete acetate derivative biosynthetic process
ontology: BP
definition:
OBSOLETE. The chemical reactions and pathways resulting in the formation of derivatives of acetic acid.


go_id: GO:0030637
term: obsolete acetate derivative catabolic process
ontology: BP
definition:
OBSOLETE. The chemical reactions and pathways resulting in the breakdown of derivatives of acetic acid.


go_id: GO:0030657
term: obsolete regulation of coenzyme and prosthetic group metabolic process
ontology: BP
definition:
OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving coenzymes and prosthetic groups.


go_id: GO:0030799
term: obsolete regulation of cyclic nucleotide metabolic process
ontology: BP
definition:
OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving cyclic nucleotides.


go_id: GO:0030800
term: obsolete negative regulation of cyclic nucleotide metabolic process
ontology: BP
definition:
OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving cyclic nucleotides.


go_id: GO:0030801
term: obsolete positive regulation of cyclic nucleotide metabolic process
ontology: BP
definition:
OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving cyclic nucleotides.


go_id: GO:0030802
term: obsolete regulation of cyclic nucleotide biosynthetic process
ontology: BP
definition:
OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cyclic nucleotides.


go_id: GO:0030803
term: obsolete negative regulation of cyclic nucleotide biosynthetic process
ontology: BP
definition:
OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cyclic nucleotides.


go_id: GO:0030804
term: obsolete positive regulation of cyclic nucleotide biosynthetic process
ontology: BP
definition:
OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cyclic nucleotides.


go_id: GO:0030806
term: obsolete negative regulation of cyclic nucleotide catabolic process
ontology: BP
definition:
OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways resulting in the breakdown of cyclic nucleotides.


go_id: GO:0030807
term: obsolete positive regulation of cyclic nucleotide catabolic process
ontology: BP
definition:
OBSOLETE. Any process that activates or increases the frequency, rate or extent of chemical reactions and pathways resulting in the breakdown of cyclic nucleotides.


go_id: GO:0030814
term: obsolete regulation of cAMP metabolic process
ontology: BP
definition:
OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).


go_id: GO:0030815
term: obsolete negative regulation of cAMP metabolic process
ontology: BP
definition:
OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).


go_id: GO:0030816
term: obsolete positive regulation of cAMP metabolic process
ontology: BP
definition:
OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).


go_id: GO:0030817
term: obsolete regulation of cAMP biosynthetic process
ontology: BP
definition:
OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).


go_id: GO:0030818
term: obsolete negative regulation of cAMP biosynthetic process
ontology: BP
definition:
OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).


go_id: GO:0030819
term: obsolete positive regulation of cAMP biosynthetic process
ontology: BP
definition:
OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).


go_id: GO:0030820
term: obsolete regulation of cAMP catabolic process
ontology: BP
definition:
OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).


go_id: GO:0030821
term: obsolete negative regulation of cAMP catabolic process
ontology: BP
definition:
OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).


go_id: GO:0030822
term: obsolete positive regulation of cAMP catabolic process
ontology: BP
definition:
OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).


go_id: GO:0030823
term: obsolete regulation of cGMP metabolic process
ontology: BP
definition:
OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving cGMP.


go_id: GO:0030824
term: obsolete negative regulation of cGMP metabolic process
ontology: BP
definition:
OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving cGMP.


go_id: GO:0030825
term: obsolete positive regulation of cGMP metabolic process
ontology: BP
definition:
OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving cGMP.


go_id: GO:0030826
term: obsolete regulation of cGMP biosynthetic process
ontology: BP
definition:
OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cGMP.


go_id: GO:0030827
term: obsolete negative regulation of cGMP biosynthetic process
ontology: BP
definition:
OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cGMP.


go_id: GO:0030828
term: obsolete positive regulation of cGMP biosynthetic process
ontology: BP
definition:
OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cGMP.


go_id: GO:0030829
term: obsolete regulation of cGMP catabolic process
ontology: BP
definition:
OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cGMP.


go_id: GO:0030830
term: obsolete negative regulation of cGMP catabolic process
ontology: BP
definition:
OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cGMP.


go_id: GO:0030831
term: obsolete positive regulation of cGMP catabolic process
ontology: BP
definition:
OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cGMP.


go_id: GO:0030939
term: obsolete response to long-day photoperiod
ontology: BP
definition:
OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a photoperiod, an intermittent cycle of light (day) and dark (night) photoperiod regimes, with the light phase being longer than the dark.


go_id: GO:0030940
term: obsolete response to short-day photoperiod
ontology: BP
definition:
OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a photoperiod, an intermittent cycle of light (day) and dark (night) photoperiod regimes, with the dark phase being longer than the light.


go_id: GO:0030969
ontology: BP
term:
obsolete mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response

definition:
OBSOLETE. The spliceosome-independent cleavage and ligation of the mRNA encoding a UFP-specific transcription factor to remove a single intron, thereby increasing both the translational efficiency of the processed mRNA and the activity of the protein it encodes.


go_id: GO:0030996
term: obsolete mitotic cell cycle arrest in response to nitrogen starvation
ontology: BP
definition:
OBSOLETE. The process in which the mitotic cell cycle is halted during one of the normal phases (G1, S, G2, M) as a result of deprivation of nitrogen.


go_id: GO:0031015
term: obsolete karyopherin docking complex
ontology: CC
definition:
OBSOLETE. A subcomplex of the nuclear pore complex that interacts with karyopherin-cargo complexes; a well-characterized example in Saccharomyces contains Asm4p, Nup53p, and Nup170p.


go_id: GO:0031079
term: obsolete picornain 3C activity
ontology: MF
definition:
OBSOLETE. Catalysis of the selective cleavage of GlnGly bond in the poliovirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly.


go_id: GO:0031275
term: obsolete regulation of lateral pseudopodium assembly
ontology: BP
definition:
OBSOLETE. Any process that modulates the frequency, rate or extent of the assembly of pseudopodia from the lateral side of the cell.


go_id: GO:0031276
term: obsolete negative regulation of lateral pseudopodium assembly
ontology: BP
definition:
OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of pseudopodia from the lateral side of the cell.


go_id: GO:0031277
term: obsolete positive regulation of lateral pseudopodium assembly
ontology: BP
definition:
OBSOLETE. Any process that activates or increases the frequency, rate or extent of the assembly of pseudopodia from the lateral side of the cell.


go_id: GO:0031368
term: obsolete Pro-X metallocarboxypeptidase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the cleavage of a Pro-Xaa bond by a metallopeptidase mechanism to release a C-terminal amino acid.


go_id: GO:0031375
term: obsolete type II fatty acid synthase complex
ontology: CC
definition:
OBSOLETE. A fatty acid synthase complex in which each polypeptide chain catalyzes a single activity.


go_id: GO:0031376
term: obsolete cytosolic type II fatty acid synthase complex
ontology: CC
definition:
OBSOLETE. A fatty acid synthase complex in which each polypeptide chain catalyzes a single activity, located in the cytosol.


go_id: GO:0031377
term: obsolete mitochondrial type II fatty acid synthase complex
ontology: CC
definition:
OBSOLETE. A fatty acid synthase complex in which each polypeptide chain catalyzes a single activity, located in the mitochondrion.


go_id: GO:0031378
term: obsolete plastid type II fatty acid synthase complex
ontology: CC
definition:
OBSOLETE. A fatty acid synthase complex in which each polypeptide chain catalyzes a single activity, located in a plastid.


go_id: GO:0031498
term: obsolete chromatin disassembly
ontology: BP
definition:
OBSOLETE. The controlled breakdown of chromatin from a higher order structure into its simpler subcomponents, DNA, histones, other proteins, and sometimes RNA.


go_id: GO:0031557
term: obsolete induction of programmed cell death in response to chemical stimulus
ontology: BP
definition:
OBSOLETE. A process which directly activates any of the steps required for programmed cell death as a result of a chemical stimulus.


go_id: GO:0031558
term: obsolete induction of apoptosis in response to chemical stimulus
ontology: BP
definition:
OBSOLETE. Any process that directly activates any of the steps required for cell death by apoptosis as a result of a chemical stimulus.


go_id: GO:0031605
term: obsolete ER proteasome core complex, alpha-subunit complex
ontology: CC
definition:
OBSOLETE. The subunits forming the outer ring of the core complex of a proteasome located in the endoplasmic reticulum of a cell.


go_id: GO:0031608
term: obsolete ER proteasome core complex, beta-subunit complex
ontology: CC
definition:
OBSOLETE. The subunits forming the inner ring of the core complex of a proteasome located in the endoplasmic reticulum of a cell.


go_id: GO:0031611
term: obsolete ER proteasome regulatory particle, base subcomplex
ontology: CC
definition:
OBSOLETE. The subunits of the regulatory particle that directly associate with the core complex of a proteasome located in the endoplasmic reticulum of a cell.


go_id: GO:0031614
term: obsolete ER proteasome regulatory particle, lid subcomplex
ontology: CC
definition:
OBSOLETE. The subunits that form the peripheral lid of the regulatory particle of a proteasome located in the endoplasmic reticulum of a cell.


go_id: GO:0031657
ontology: BP
term:
obsolete regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle

definition:
OBSOLETE. Any process that controls the frequency, rate or extent of G1 cyclin-dependent protein serine/threonine kinase activity contributing to the G1/S transition of the cell cycle.


go_id: GO:0031658
ontology: BP
term:
obsolete negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle

definition:
OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G1/S transition of the cell cycle.


go_id: GO:0031659
ontology: BP
term:
obsolete positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle

definition:
OBSOLETE. Any process that activates or increases the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G1/S transition of the cell cycle.


go_id: GO:0031660
ontology: BP
term:
obsolete regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle

definition:
OBSOLETE. Any process that modulates the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G2/M transition of the cell cycle.


go_id: GO:0031661
ontology: BP
term:
obsolete negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle

definition:
OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G2/M transition of the cell cycle.


go_id: GO:0031684
term: obsolete heterotrimeric G-protein complex cycle
ontology: BP
definition:
OBSOLETE. The series of molecular events that generate a signal through the activation of G-protein subunits and recycling of these subunits.


go_id: GO:0031937
term: obsolete positive regulation of chromatin silencing
ontology: BP
definition:
OBSOLETE. Any process that activates or increases the frequency, rate or extent of chromatin silencing.


go_id: GO:0031938
term: obsolete regulation of chromatin silencing at telomere
ontology: BP
definition:
OBSOLETE. Any process that affects the rate, extent or location of chromatin silencing at telomeres.


go_id: GO:0031939
term: obsolete negative regulation of chromatin silencing at telomere
ontology: BP
definition:
OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of chromatin silencing at telomeres.


go_id: GO:0031940
term: obsolete positive regulation of chromatin silencing at telomere
ontology: BP
definition:
OBSOLETE. Any process that activates or increases the frequency, rate or extent of chromatin silencing at telomeres.


go_id: GO:0032155
term: obsolete cell division site part
ontology: CC
definition:
OBSOLETE. Any constituent part of the cell division plane, the eventual plane of cell division in a dividing cell.


go_id: GO:0032234
term: obsolete regulation of calcium ion transport via store-operated calcium channel activity
ontology: BP
definition:
OBSOLETE. Any process that modulates the frequency, rate or extent of the directed movement of calcium ions via a store-operated calcium channel.


go_id: GO:0032235
term: obsolete negative regulation of calcium ion transport via store-operated calcium channel activity
ontology: BP
definition:
OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of calcium ions via a store-operated calcium channel.


go_id: GO:0032236
term: obsolete positive regulation of calcium ion transport via store-operated calcium channel activity
ontology: BP
definition:
OBSOLETE. Any process that activates or increases the frequency, rate or extent of the directed movement of calcium ions via a store-operated calcium channel.


go_id: GO:0032362
term: obsolete FAD catabolic process
ontology: BP
definition:
OBSOLETE. The chemical reactions and pathways resulting in the breakdown of FAD, the oxidized form of flavin-adenine dinucleotide.


go_id: GO:0032617
term: obsolete interleukin-14 production
ontology: BP
definition:
OBSOLETE. The appearance of interleukin-14 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0032697
term: obsolete negative regulation of interleukin-14 production
ontology: BP
definition:
OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-14 production.


go_id: GO:0032737
term: obsolete positive regulation of interleukin-14 production
ontology: BP
definition:
OBSOLETE. Any process that activates or increases the frequency, rate, or extent of interleukin-14 production.


go_id: GO:0032800
term: obsolete receptor biosynthetic process
ontology: BP
definition:
OBSOLETE. The chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.


go_id: GO:0033124
term: obsolete regulation of GTP catabolic process
ontology: BP
definition:
OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of GTP, guanosine triphosphate.


go_id: GO:0033125
term: obsolete negative regulation of GTP catabolic process
ontology: BP
definition:
OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of GTP, guanosine triphosphate.


go_id: GO:0033126
term: obsolete positive regulation of GTP catabolic process
ontology: BP
definition:
OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of GTP, guanosine triphosphate.


go_id: GO:0033127
term: obsolete regulation of histone phosphorylation
ontology: BP
definition:
OBSOLETE. Any process that modulates the frequency, rate or extent of the addition of one or more phosphate groups to a histone protein.


go_id: GO:0033128
term: obsolete negative regulation of histone phosphorylation
ontology: BP
definition:
OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of one or more phosphate groups to a histone protein.


go_id: GO:0033129
term: obsolete positive regulation of histone phosphorylation
ontology: BP
definition:
OBSOLETE. Any process that activates or increases the frequency, rate or extent of the addition of one or more phosphate groups to a histone protein.


go_id: GO:0033158
term: obsolete regulation of protein import into nucleus, translocation
ontology: BP
definition:
OBSOLETE. Any process that modulates the vectorial transfer of a protein from the cytoplasm into the nucleus, across the nuclear membrane.


go_id: GO:0033159
term: obsolete negative regulation of protein import into nucleus, translocation
ontology: BP
definition:
OBSOLETE. Any process that stops, prevents or reduces the vectorial transfer of a protein from the cytoplasm into the nucleus, across the nuclear membrane.


go_id: GO:0033160
term: obsolete positive regulation of protein import into nucleus, translocation
ontology: BP
definition:
OBSOLETE. Any process that activates or increases the vectorial transfer of a protein from the cytoplasm into the nucleus, across the nuclear membrane.


go_id: GO:0033168
term: obsolete conversion of ds siRNA to ss siRNA involved in RNA interference
ontology: BP
definition:
OBSOLETE. The process in which double-stranded siRNA molecules are converted to single-stranded siRNAs; required for the formation of a mature RITS complex during RNA interference.


go_id: GO:0033171
term: obsolete nucleoprotein filament-forming ATPase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate to drive the assembly of proteins such as Rad51p onto single-stranded (ss) DNA to form a helical nucleoprotein filament.


go_id: GO:0033187
term: obsolete inositol hexakisphosphate 4-kinase or 6-kinase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 4-diphospho-1D-myo-inositol (1,2,3,5,6)pentakisphosphate, and ATP + 1D-myo-inositol hexakisphosphate = ADP + 6-diphospho-1D-myo-inositol (1,2,3,4,5)pentakisphosphate.


go_id: GO:0033199
term: obsolete inositol heptakisphosphate 4-kinase or 6-kinase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: ATP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate = 4,5-bisdiphosphoinositol-1D-myoinositol (1,2,3,6)tetrakisphosphate, and ATP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate = 5,6-bisdiphosphoinositol-1D-myoinositol (1,2,3,4)tetrakisphosphate.


go_id: GO:0033236
term: obsolete 11-beta-hydroxysteroid dehydrogenase (NAD+) activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: an 11-beta-hydroxysteroid + NAD+ = an 11-oxosteroid + NADH + H+.


go_id: GO:0033237
term: obsolete 11-beta-hydroxysteroid dehydrogenase (NADP+) activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: an 11-beta-hydroxysteroid + NADP+ = an 11-oxosteroid + NADPH + H+.


go_id: GO:0033261
term: obsolete regulation of S phase
ontology: BP
definition:
OBSOLETE. A cell cycle process that modulates the rate or extent of the progression through the S phase of the cell cycle.


go_id: GO:0033264
term: obsolete bontoxilysin activity
ontology: MF
definition:
OBSOLETE. Catalysis of limited hydrolysis of proteins of the neuroexocytosis apparatus, synaptobrevins, SNAP25 or syntaxin. No detected action on small molecule substrates.


go_id: GO:0033547
ontology: BP
term:
obsolete myo-inositol hexakisphosphate biosynthetic process, via direct phosphorylation of inositol 1,4,5-trisphosphate

definition:
OBSOLETE. The chemical reactions and pathways resulting in the formation of 1D myo-inositol 1,2,3,4,5,6-hexakisphosphate, phytate, by a pathway using inositol 1,4,5-trisphosphate produced from phosphatidylinositol 4,5-biphosphate hydrolysis by phospholipase C; in this pathway, inositol 1,4,5-trisphosphate is successively phosphorylated to yield inositol hexakisphosphate.


go_id: GO:0033575
term: obsolete protein glycosylation at cell surface
ontology: BP
definition:
OBSOLETE. The addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid at the surface of a cell.


go_id: GO:0033576
term: obsolete protein glycosylation in cytosol
ontology: BP
definition:
OBSOLETE. The addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in the cytosol.


go_id: GO:0033577
term: obsolete protein glycosylation in endoplasmic reticulum
ontology: BP
definition:
OBSOLETE. The addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in the endoplasmic reticulum.


go_id: GO:0033578
term: obsolete protein glycosylation in Golgi
ontology: BP
definition:
OBSOLETE. The addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in any compartment of the Golgi apparatus.


go_id: GO:0033581
term: obsolete protein galactosylation in Golgi
ontology: BP
definition:
OBSOLETE. The addition of a galactose unit to a protein amino acid in any compartment of the Golgi apparatus.


go_id: GO:0033662
term: obsolete modulation by symbiont of host defense-related protein level
ontology: BP
definition:
OBSOLETE. The alternation by a symbiont of the levels of defense-related proteins in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033663
term: obsolete negative regulation by symbiont of host defense-related protein level
ontology: BP
definition:
OBSOLETE. Any process in which the symbiont reduces of the levels of defense-related proteins in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033664
term: obsolete positive regulation by symbiont of host defense-related protein level
ontology: BP
definition:
OBSOLETE. Any process in which the symbiont activates, maintains or increases levels of defense-related proteins in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033665
term: obsolete regulation of growth or development of symbiont in host
ontology: BP
definition:
OBSOLETE. Any process by which the symbiont regulates the increase in its size or mass, or its progression from an initial condition to a later condition, within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down. The host is defined as the larger of the organisms involved in the symbiotic interaction.


go_id: GO:0033666
term: obsolete positive regulation of growth or development of symbiont in host
ontology: BP
definition:
OBSOLETE. Any process by which the symbiont activates, maintains or increases its size or mass or its progression from an initial condition to a later condition, within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction.


go_id: GO:0033667
term: obsolete negative regulation of growth or development of symbiont in host
ontology: BP
definition:
OBSOLETE. Any process by which the symbiont stops, prevents or reduces its increase in size or mass or its progression from an initial condition to a later condition, within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction.


go_id: GO:0033697
term: obsolete positive regulation of extent of heterochromatin assembly
ontology: BP
definition:
OBSOLETE. Any process that increases the extent of heterochromatin formation; increases the size of a chromosomal region converted to heterochromatin.


go_id: GO:0033706
term: obsolete quinate/shikimate dehydrogenase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reactions: L-quinate + NAD(P)+ = 3-dehydroquinate + NAD(P)H + H+, and shikimate + NAD(P)+ = 3-dehydroshikimate + NAD(P)H + H+.


go_id: GO:0033747
term: obsolete versatile peroxidase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reactions: Reactive Black 5 + hydrogen peroxide = oxidized Reactive Black 5 + 2 H2O, and donor + hydrogen peroxide = oxidized donor + 2 H2O.


go_id: GO:0033751
term: obsolete linoleate 8R-lipoxygenase
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: linoleate + O2 = (9Z,12Z)-(7S,8S)-dihydroxyoctadeca-9,12-dienoate.


go_id: GO:0033804
term: obsolete glycine/sarcosine N-methyltransferase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reactions: S-adenosyl-L-methionine + glycine = S-adenosyl-L-homocysteine + sarcosine, and S-adenosyl-L-methionine + sarcosine = S-adenosyl-L-homocysteine + N,N-dimethylglycine.


go_id: GO:0033805
term: obsolete sarcosine/dimethylglycine N-methyltransferase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reactions: S-adenosyl-L-methionine + sarcosine = S-adenosyl-L-homocysteine + N,N-dimethylglycine, and S-adenosyl-L-methionine + N,N-dimethylglycine = S-adenosyl-L-homocysteine + betaine.


go_id: GO:0033868
term: obsolete Goodpasture-antigen-binding protein kinase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: ATP + Goodpasture antigen-binding protein = ADP + Goodpasture antigen-binding phosphoprotein.


go_id: GO:0033884
term: obsolete phosphoethanolamine/phosphocholine phosphatase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reactions: O-phosphoethanolamine + H2O = ethanolamine + phosphate, and phosphocholine + H2O = choline + phosphate.


go_id: GO:0033903
term: obsolete endo-1,3(4)-beta-glucanase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the endohydrolysis of 1,3- or 1,4-linkages in beta-D-glucans when the glucose residue whose reducing group is involved in the linkage to be hydrolysed is itself substituted at C-3.


go_id: GO:0033955
term: obsolete mitochondrial DNA inheritance
ontology: BP
definition:
OBSOLETE. The process in which copies of the mitochondrial genome are distributed into daughter mitochondria upon mitochondrial fission.


go_id: GO:0034225
ontology: BP
term:
obsolete regulation of transcription from RNA polymerase II promoter in response to zinc ion starvation

definition:
OBSOLETE. Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is deprived of zinc ions.


go_id: GO:0034339
term: obsolete regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor
ontology: BP
definition:
OBSOLETE. Any process in which a ligand-bound hormone receptor acts in the nucleus to modulate the frequency, rate or extent of transcription from an RNA polymerase II promoter.


go_id: GO:0034401
term: obsolete chromatin organization involved in regulation of transcription
ontology: BP
definition:
OBSOLETE. Any cellular process that results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin that modulates the rate, frequency or extent of DNA-dependent transcription.


go_id: GO:0034419
term: obsolete L-2-hydroxyglutarate oxidase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: L-2-hydroxyglutarate + O2 = 2-oxoglutarate + hydrogen peroxide.


go_id: GO:0034624
term: obsolete DNA recombinase assembly involved in gene conversion at mating-type locus
ontology: BP
definition:
OBSOLETE. The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) into higher order oligomers on single-stranded DNA, involved in the conversion of the mating-type locus from one allele to another.


go_id: GO:0034648
term: obsolete histone demethylase activity (H3-dimethyl-K4 specific)
ontology: MF
definition:
OBSOLETE. Catalysis of the removal of a methyl group from dimethylated lysine at position 4 of the histone H3 protein.


go_id: GO:0034649
term: obsolete histone demethylase activity (H3-monomethyl-K4 specific)
ontology: MF
definition:
OBSOLETE. Catalysis of the removal of a methyl group from monomethylated lysine at position 4 of the histone H3 protein.


go_id: GO:0034652
term: obsolete extrachromosomal circular DNA localization involved in cell aging
ontology: BP
definition:
OBSOLETE. A process in which extrachromosomal circular DNA molecules are transported to, or maintained in, a specific location in cells contributing to their aging.


go_id: GO:0034725
term: obsolete DNA replication-dependent nucleosome disassembly
ontology: BP
definition:
OBSOLETE. The controlled breakdown of nucleosomes on newly replicated DNA, coupled to strand elongation.


go_id: GO:0034884
term: obsolete gamma-N-formylaminovinylacetaldehyde dehydrogenase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: gamma-N-formylaminovinylacetaldehyde + H2O = gamma-N-formylaminovinylacetate + 2 H+ + 2 e-.


go_id: GO:0034887
term: obsolete 1,4-dihydroisonicotinate 2,3-dioxygenase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: 1,4-dihydroisonicotinate + O2 = gamma-N-formylaminovinylacetaldehyde + CO2.


go_id: GO:0035042
term: obsolete fertilization, exchange of chromosomal proteins
ontology: BP
definition:
OBSOLETE. Replacement of sperm-specific chromosomal proteins with somatic histones, to allow the paternal genome to acquire a nucleosomal chromatin organization compatible with nuclear activity.


go_id: GO:0035048
term: obsolete splicing factor protein import into nucleus
ontology: BP
definition:
OBSOLETE. The directed movement of a pre-mRNA splicing factor from the cytoplasm into the nucleus, across the nuclear membrane.


go_id: GO:0035109
term: obsolete imaginal disc-derived limb morphogenesis
ontology: BP
definition:
OBSOLETE. The process in which the anatomical structures of limbs that are derived from an imaginal disc are generated and organized. A limb is an appendage of an animal used for locomotion or grasping. An example of this process is found in Drosophila melanogaster.


go_id: GO:0035110
term: obsolete leg morphogenesis
ontology: BP
definition:
OBSOLETE. The process in which the anatomical structures of a leg are generated and organized. A leg is a limb on which an animal walks and stands.


go_id: GO:0035111
term: obsolete leg joint morphogenesis
ontology: BP
definition:
OBSOLETE. The process in which the anatomical structures of a leg joint are generated and organized. The leg joint is a flexible region that separates the rigid sections of a leg to allow movement in a controlled manner. One example is the knee, which separates the leg tibia and femur.


go_id: GO:0035121
term: obsolete tail morphogenesis
ontology: BP
definition:
OBSOLETE. The process in which the anatomical structures of the tail are generated and organized. The tail is the hindmost part of some animals.


go_id: GO:0035286
term: obsolete leg segmentation
ontology: BP
definition:
OBSOLETE. Division of a leg into a series of semi-repetitive parts or segments. Most arthropod appendages are visibly segmented; the Drosophila leg for example has nine segments, each separated from the next by a flexible joint.


go_id: GO:0035300
term: obsolete inositol-1,3,4-trisphosphate 5/6-kinase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reactions: ATP + 1D-myo-inositol 1,3,4-trisphosphate = ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate, and ATP + 1D-myo-inositol 1,3,4-trisphosphate = ADP + 1D-myo-inositol 1,3,4,6-tetrakisphosphate.


go_id: GO:0035391
term: obsolete maintenance of chromatin silencing at silent mating-type cassette
ontology: BP
definition:
OBSOLETE. The maintenance of chromatin in a transcriptionally silent state such as heterochromatin at silent mating-type loci.


go_id: GO:0035392
term: obsolete maintenance of chromatin silencing at telomere
ontology: BP
definition:
OBSOLETE. The maintenance of chromatin in a transcriptionally silent state such as heterochromatin at the telomere.


go_id: GO:0035407
term: obsolete histone H3-T11 phosphorylation
ontology: BP
definition:
OBSOLETE. The modification of histone H3 by the addition of an phosphate group to a threonine residue at position 11 of the histone.


go_id: GO:0035408
term: obsolete histone H3-T6 phosphorylation
ontology: BP
definition:
OBSOLETE. The modification of histone H3 by the addition of an phosphate group to a threonine residue at position 6 of the histone.


go_id: GO:0035409
term: obsolete histone H3-Y41 phosphorylation
ontology: BP
definition:
OBSOLETE. The modification of histone H3 by the addition of a phosphate group to a tyrosine residue at position 41 of the histone.


go_id: GO:0035415
term: obsolete regulation of mitotic prometaphase
ontology: BP
definition:
OBSOLETE. Any process that modulates the frequency, rate or extent of mitotic prometaphase, the stage following prophase in mitosis (in higher eukaryotes) during which the nuclear envelope is disrupted and breaks into membrane vesicles, and the spindle microtubules enter the nuclear region.


go_id: GO:0035416
term: obsolete positive regulation of mitotic prometaphase
ontology: BP
definition:
OBSOLETE. Any process that activates or increases the frequency, rate or extent of mitotic prometaphase, the stage following prophase in mitosis (in higher eukaryotes) during which the nuclear envelope is disrupted and breaks into membrane vesicles, and the spindle microtubules enter the nuclear region.


go_id: GO:0035417
term: obsolete negative regulation of mitotic prometaphase
ontology: BP
definition:
OBSOLETE. Any process that stops, prevents or reduces the rate or extent of mitotic prometaphase, the stage following prophase in mitosis (in higher eukaryotes) during which the nuclear envelope is disrupted and breaks into membrane vesicles, and the spindle microtubules enter the nuclear region.


go_id: GO:0035419
term: obsolete activation of MAPK activity involved in innate immune response
ontology: BP
definition:
OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens.


go_id: GO:0035420
term: obsolete MAPK cascade involved in innate immune response
ontology: BP
definition:
OBSOLETE. A MAPK cascade that contributes to an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens.


go_id: GO:0035421
term: obsolete activation of MAPKK activity involved in innate immune response
ontology: BP
definition:
OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase kinase in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens.


go_id: GO:0035422
term: obsolete activation of MAPKKK activity involved in innate immune response
ontology: BP
definition:
OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens.


go_id: GO:0035423
term: obsolete inactivation of MAPK activity involved in innate immune response
ontology: BP
definition:
OBSOLETE. Any process that terminates the activity of the active enzyme MAP kinase in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens.


go_id: GO:0035424
term: obsolete MAPK import into nucleus involved in innate immune response
ontology: BP
definition:
OBSOLETE. The directed movement of a MAP kinase to the nucleus in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens.


go_id: GO:0035465
ontology: BP
term:
obsolete regulation of transforming growth factor beta receptor signaling pathway involved in determination of lateral mesoderm left/right asymmetry

definition:
OBSOLETE. Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway that is involved in the determination of the lateral plate mesoderm with respect to its left and right halves.


go_id: GO:0035528
term: obsolete UDP-N-acetylglucosamine biosynthesis involved in chitin biosynthesis
ontology: BP
definition:
OBSOLETE. The chemical reactions and pathways resulting in the formation of UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine in glycosidic linkage with uridine diphosphate, that contribute to the biosynthesis of chitin.


go_id: GO:0035557
term: obsolete intracellular signal transduction involved in cell surface receptor linked signaling
ontology: BP
definition:
OBSOLETE. The process in which a signal is passed on from a receptor at the cell surface to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.


go_id: GO:0035558
term: obsolete phosphatidylinositol 3-kinase cascade involved in insulin receptor signaling
ontology: BP
definition:
OBSOLETE. The process in which a signal is passed from the insulin receptor to components of the phosphatidylinositol 3-kinase (PI3K) cascade, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.


go_id: GO:0035559
term: obsolete MAPKKK cascade involved in epidermal growth factor receptor signaling
ontology: BP
definition:
OBSOLETE. The process in which a signal is passed from the epidermal growth factor receptor (EGFR) to components of the MAPKKK cascade, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.


go_id: GO:0035569
term: obsolete N-terminal peptidyl-proline trimethylation
ontology: BP
definition:
OBSOLETE. The trimethylation of the N-terminal proline of proteins to form the derivative N,N,N-trimethylproline.


go_id: GO:0035625
ontology: BP
term:
obsolete epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway

definition:
OBSOLETE. The process in which an epidermal growth factor-activated receptor is activated via signaling events from a consequence of a G protein-coupled . This is an example of cross-talk between the EGF and GPCR signaling pathways.


go_id: GO:0035656
term: obsolete kinesin-associated melanosomal adaptor activity
ontology: MF
definition:
OBSOLETE. The activity of linking kinesins, cytoplasmic proteins responsible for moving vesicles and organelles towards the distal end of microtubules, to melanosomes.


go_id: GO:0035737
term: obsolete injection of substance in to other organism
ontology: BP
definition:
OBSOLETE. The process of forcing a substance into another organism, either by penetrating the skin of the other organism or by applying the substance externally to a sensitive tissue such as those that surround the eyes.


go_id: GO:0035826
term: obsolete rubidium ion transport
ontology: BP
definition:
OBSOLETE. The directed movement of rubidium ions (Rb+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0035829
term: obsolete renal rubidium ion absorption
ontology: BP
definition:
OBSOLETE. A renal system process in which rubidium ions are taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.


go_id: GO:0035897
term: obsolete proteolysis in other organism
ontology: BP
definition:
OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the hydrolysis of proteins in another organism by cleavage of their peptide bonds.


go_id: GO:0035940
term: obsolete negative regulation of peptidase activity in other organism
ontology: BP
definition:
OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of peptidase activity, the catalysis of the hydrolysis of peptide bonds in a protein, in a second organism.


go_id: GO:0035947
ontology: BP
term:
obsolete regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter

definition:
OBSOLETE. Any process that modulates the frequency, rate or extent of gluconeogenesis, by regulation of transcription from an RNA polymerase II promoter.


go_id: GO:0035948
ontology: BP
term:
obsolete positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter

definition:
OBSOLETE. Any process that activates or increases the frequency, rate or extent of gluconeogenesis by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.


go_id: GO:0035949
ontology: BP
term:
obsolete positive regulation of gluconeogenesis by negative regulation of transcription from RNA polymerase II promoter

definition:
OBSOLETE. Any process that activates or increases the frequency, rate or extent of gluconeogenesis by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.


go_id: GO:0035950
ontology: BP
term:
obsolete regulation of oligopeptide transport by regulation of transcription from RNA polymerase II promoter

definition:
OBSOLETE. Any process that modulates the frequency, rate or extent of oligopeptide transport, by regulation of transcription from an RNA polymerase II promoter.


go_id: GO:0035951
ontology: BP
term:
obsolete positive regulation of oligopeptide transport by positive regulation of transcription from RNA polymerase II promoter

definition:
OBSOLETE. Any process that activates or increases the frequency, rate or extent of oligopeptide transport by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.


go_id: GO:0035952
ontology: BP
term:
obsolete negative regulation of oligopeptide transport by negative regulation of transcription from RNA polymerase II promoter

definition:
OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of oligopeptide transport by stopping, preventing or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.


go_id: GO:0035953
ontology: BP
term:
obsolete regulation of dipeptide transport by regulation of transcription from RNA polymerase II promoter

definition:
OBSOLETE. Any process that modulates the frequency, rate or extent of dipeptide transport, by regulation of transcription from an RNA polymerase II promoter.


go_id: GO:0035954
ontology: BP
term:
obsolete positive regulation of dipeptide transport by positive regulation of transcription from RNA polymerase II promoter

definition:
OBSOLETE. Any process that activates or increases the frequency, rate or extent of dipeptide transport by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.


go_id: GO:0035955
ontology: BP
term:
obsolete negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter

definition:
OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of dipeptide transport by stopping, preventing or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.


go_id: GO:0035956
ontology: BP
term:
obsolete regulation of starch catabolic process by regulation of transcription from RNA polymerase II promoter

definition:
OBSOLETE. Any process that modulates the frequency, rate or extent of the breakdown of starch, by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter.


go_id: GO:0035957
ontology: BP
term:
obsolete positive regulation of starch catabolic process by positive regulation of transcription from RNA polymerase II promoter

definition:
OBSOLETE. Any process that activates or increases the frequency, rate or extent of the breakdown of starch, by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.


go_id: GO:0035958
ontology: BP
term:
obsolete regulation of glyoxylate cycle by regulation of transcription from RNA polymerase II promoter

definition:
OBSOLETE. Any process that modulates the frequency, rate or extent of the glyoxylate cycle by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter.


go_id: GO:0035959
ontology: BP
term:
obsolete positive regulation of glyoxylate cycle by positive regulation of transcription from RNA polymerase II promoter

definition:
OBSOLETE. Any process that activates or increases the frequency, rate or extent of the glyoxylate cycle by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.


go_id: GO:0035960
ontology: BP
term:
obsolete regulation of ergosterol biosynthetic process by regulation of transcription from RNA polymerase II promoter

definition:
OBSOLETE. Any process that modulates the frequency, rate or extent of ergosterol biosynthetic process by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter.


go_id: GO:0035961
ontology: BP
term:
obsolete positive regulation of ergosterol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter

definition:
OBSOLETE. Any process that activates or increases the frequency, rate or extent of ergosterol biosynthesis by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.


go_id: GO:0035968
term: obsolete regulation of sterol import by regulation of transcription from RNA polymerase II promoter
ontology: BP
definition:
OBSOLETE. Any process that modulates the frequency, rate or extent of sterol import, by regulation of transcription from an RNA polymerase II promoter.


go_id: GO:0035969
ontology: BP
term:
obsolete positive regulation of sterol import by positive regulation of transcription from RNA polymerase II promoter

definition:
OBSOLETE. Any process that activates or increases the frequency, rate or extent of sterol import by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.


go_id: GO:0035978
term: obsolete histone H2A-S139 phosphorylation
ontology: BP
definition:
OBSOLETE. The modification of histone H2A by the addition of an phosphate group to a serine residue at position 139 of the histone.


go_id: GO:0035980
term: obsolete invasive growth in response to nitrogen limitation
ontology: BP
definition:
OBSOLETE. The growth of colonies in filamentous chains of cells as a result of a reduced availability of nitrogen.


go_id: GO:0035982
term: obsolete age-dependent behavioral decline
ontology: BP
definition:
OBSOLETE. A developmental process that arises as an organism progresses toward the end of its lifespan that results in a decline in behavioral activities such as locomotory behavior, and learning or memory.


go_id: GO:0035986
term: obsolete senescence-associated heterochromatin focus assembly
ontology: BP
definition:
OBSOLETE. The assembly of chromatin into senescence-associated heterochromatin foci (SAHF), transcriptionally-silent heterochromatin structures present in senescent cells, containing the condensed chromatin of one chromosome, and enriched for histone modifications. Formation of these chromatin structures is thought to repress expression of proliferation-promoting genes.


go_id: GO:0036045
term: obsolete peptidyl-lysine malonylation
ontology: BP
definition:
OBSOLETE. The addition of a malonyl group (CO-CH2-CO) to peptidyl-lysine to form N6-malonyl-L-lysine.


go_id: GO:0036083
ontology: BP
term:
obsolete positive regulation of unsaturated fatty acid biosynthetic process by positive regulation of transcription from RNA polymerase II promoter

definition:
OBSOLETE. Any process that activates or increases the frequency, rate or extent of unsaturated fatty acid biosynthetic process by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.


go_id: GO:0036095
ontology: BP
term:
obsolete positive regulation of invasive growth in response to glucose limitation by positive regulation of transcription from RNA polymerase II promoter

definition:
OBSOLETE. Any process that activates or increases the frequency, rate or extent of invasive growth as a result of deprivation of glucose, by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.


go_id: GO:0036096
term: obsolete 3'-5'-exoribonuclease activity involved in pre-miRNA 3'-end processing
ontology: MF
definition:
OBSOLETE. Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule that contributes to forming the mature 3' end of a miRNA from a pre-miRNA.


go_id: GO:0036129
ontology: BP
term:
obsolete negative regulation of transcription from RNA polymerase II promoter in response to hydrogen peroxide

definition:
OBSOLETE. Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hydrogen peroxide (H2O2) stimulus.


go_id: GO:0036206
term: obsolete regulation of histone gene expression
ontology: BP
definition:
OBSOLETE. Any process that modulates the frequency, rate or extent of expression of a histone-encoding gene. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein.


go_id: GO:0036207
term: obsolete positive regulation of histone gene expression
ontology: BP
definition:
OBSOLETE. Any process that increases the frequency, rate or extent of expression of a histone-encoding gene. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein.


go_id: GO:0036208
term: obsolete negative regulation of histone gene expression
ontology: BP
definition:
OBSOLETE. Any process that decreases the frequency, rate or extent of expression of a histone-encoding gene. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein.


go_id: GO:0036226
term: obsolete mitotic cell cycle arrest in response to glucose starvation
ontology: BP
definition:
OBSOLETE. The process in which the mitotic cell cycle is halted during one of the normal phases (G1, S, G2, M) as a result of deprivation of glucose.


go_id: GO:0036251
ontology: BP
term:
obsolete positive regulation of transcription from RNA polymerase II promoter in response to salt stress

definition:
OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under salt stress. The stress is usually an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.


go_id: GO:0036283
ontology: BP
term:
obsolete positive regulation of transcription factor import into nucleus in response to oxidative stress

definition:
OBSOLETE. Any process that activates or increases the frequency, rate or extent of the movement of a transcription factor from the cytoplasm to the nucleus under conditions of oxidative stress.


go_id: GO:0036385
term: obsolete nucleoid DNA packaging
ontology: BP
definition:
OBSOLETE. Any process in which DNA and associated proteins are formed into a compact, orderly structure within a nucleoid.


go_id: GO:0036404
term: obsolete conversion of ds siRNA to ss siRNA
ontology: BP
definition:
OBSOLETE. The process in which double-stranded small interfering RNA (ds siRNA) molecules are converted to single-stranded small interfering RNA (ss siRNA).


go_id: GO:0036413
term: obsolete histone H3-R26 citrullination
ontology: BP
definition:
OBSOLETE. The hydrolysis of peptidyl-arginine to form peptidyl-citrulline at position 26 in histone H3.


go_id: GO:0036425
term: obsolete D-phosphoserine phosphatase activity
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: O-phospho-D-serine + H2O = L-serine + phosphate, on a free amino acid.


go_id: GO:0036523
term: obsolete induction by symbiont of host cytokine production
ontology: BP
definition:
OBSOLETE. Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of cytokine production by the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0038040
term: obsolete cross-receptor activation within G-protein coupled receptor heterodimer
ontology: BP
definition:
OBSOLETE. Activation of one protomer of a consequence of a G protein-coupled (GPCR) heterodimer by the associated subunit. For example, agonist occupancy in one protomer of a GPCR dimer may activate the associated promoter.


go_id: GO:0038053
ontology: MF
term:
obsolete transcription factor activity, estrogen-activated RNA polymerase II transcription factor binding

definition:
OBSOLETE. Combining with estrogen and transmitting the signal to the transcriptional machinery by binding to an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to modulate transcription. For example, estrogen-bound receptors can bind to transcription factor complexes to regulate transcription of genes whose promoters do not contain estrogen response elements.


go_id: GO:0038067
term: obsolete MAP kinase activity involved in cell wall organization or biogenesis
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: protein + ATP = protein phosphate + ADP by a mitogen-activated protein kinase, as part of a MAPK signaling cascade that contributes to cell wall organization or biogenesis.


go_id: GO:0038068
term: obsolete MAP kinase kinase activity involved in cell wall organization or biogenesis
ontology: MF
definition:
OBSOLETE. Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate, as part of a MAPK signaling cascade that contributes to cell wall organization or biogenesis.


go_id: GO:0038069
term: obsolete MAP kinase phosphatase activity involved in regulation of cell wall biogenesis
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate, where the MAP kinase (MAPK) is part of a MAPK signaling cascade that contributes to cell wall biogenesis.


go_id: GO:0038070
term: obsolete MAP kinase kinase kinase activity involved in cell wall organization or biogenesis
ontology: MF
definition:
OBSOLETE. Catalysis of the phosphorylation and activation of a MAP kinase kinase (MAPKK), as part of a MAPK signaling cascade that contributes to cell wall organization or biogenesis.


go_id: GO:0038071
term: obsolete MAP kinase activity involved in conjugation with cellular fusion
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: protein + ATP = protein phosphate + ADP by a mitogen-activated protein kinase, as part of a MAPK signaling cascade that contributes to conjugation with cellular fusion.


go_id: GO:0038072
term: obsolete MAP kinase kinase activity involved in conjugation with cellular fusion
ontology: MF
definition:
OBSOLETE. Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate, as part of a MAPK signaling cascade that contributes to conjugation with cellular fusion.


go_id: GO:0038073
term: obsolete MAP kinase kinase kinase activity involved in conjugation with cellular fusion
ontology: MF
definition:
OBSOLETE. Catalysis of the phosphorylation and activation of a MAP kinase kinase (MAPKK), as part of a MAPK signaling cascade that contributes to cell wall biogenesis.


go_id: GO:0038074
term: obsolete MAP kinase phosphatase activity involved in regulation of conjugation with cellular fusion
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate, where the MAP kinase (MAPK) is part of a MAPK signaling cascade that contributes to conjugation with cellular fusion.


go_id: GO:0038075
term: obsolete MAP kinase activity involved in innate immune response
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: protein + ATP = protein phosphate + ADP by a mitogen-activated protein kinase, as part of a MAPK signaling cascade that contributes to an innate immune response.


go_id: GO:0038076
term: obsolete MAP kinase kinase activity involved in innate immune response
ontology: MF
definition:
OBSOLETE. Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate, as part of a MAPK signaling cascade that contributes to an innate immune response.


go_id: GO:0038077
term: obsolete MAP kinase kinase kinase activity involved in innate immune response
ontology: MF
definition:
OBSOLETE. Catalysis of the phosphorylation and activation of a MAP kinase kinase (MAPKK), as part of a MAPK signaling cascade that contributes to an innate immune response.


go_id: GO:0038078
term: obsolete MAP kinase phosphatase activity involved in regulation of innate immune response
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate, where the MAP kinase (MAPK) is part of a MAPK signaling cascade that contributes to an innate immune response.


go_id: GO:0038079
term: obsolete MAP kinase activity involved in osmosensory signaling pathway
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: protein + ATP = protein phosphate + ADP by a mitogen-activated protein kinase, as part of a MAPK signaling cascade that passes on a signal within an osmosensory signaling pathway.


go_id: GO:0038080
term: obsolete MAP kinase kinase activity involved in osmosensory signaling pathway
ontology: MF
definition:
OBSOLETE. Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate, as part of a MAPK signaling cascade that passes on a signal within an osmosensory signaling pathway.


go_id: GO:0038081
term: obsolete MAP kinase kinase kinase activity involved in osmosensory signaling pathway
ontology: MF
definition:
OBSOLETE. Catalysis of the phosphorylation and activation of a MAP kinase kinase (MAPKK), as part of a MAPK signaling cascade that passes on a signal within an osmosensory signaling pathway.


go_id: GO:0038082
term: obsolete MAP kinase phosphatase activity involved in regulation of osmosensory signaling pathway
ontology: MF
definition:
OBSOLETE. Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate, where the MAP kinase (MAPK) is part of a MAPK signaling cascade that passes on a signal within an osmosensory signaling pathway.


go_id: GO:0039510
term: obsolete suppression by virus of host ATP-dependent RNA helicase activity
ontology: BP
definition:
OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host ATP-dependent RNA helicase activity.


go_id: GO:0039541
term: obsolete suppression by virus of host RIG-I via RIG-I binding
ontology: BP
definition:
OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of RIG-I (also known as DDX58) by binding to RIG-I itself.


go_id: GO:0039542
term: obsolete suppression by virus of host RIG-I K63-linked ubiquitination
ontology: BP
definition:
OBSOLETE. Any process in which a virus stops, prevents, or reduces the rate or extent of K63-linked ubiquitination of RIG-I (also known as DDX58), thereby suppressing RIG-I signal transduction. Lys63-linked ubiquitination of the N-terminal CARD domains of RIG-I is crucial for the cytosolic RIG-I signaling pathway to elicit host antiviral innate immunity.


go_id: GO:0039543
term: obsolete suppression by virus of host RIG-I activity by viral RNA 5' processing
ontology: BP
definition:
OBSOLETE. The post-transcriptional removal by a virus of the 5' triphosphate group of their viral RNA, thereby preventing host RIG-I from recognizing viral RNA in the host cell. The intracellular pattern recognition receptor RIG-I (also known as DDX58) recognizes viral RNAs containing 5' triphosphates; removal by the virus of the 5'-terminal triphosphate group from their genome protects the viral RNA from RIG-recognition.


go_id: GO:0039544
term: obsolete suppression by virus of host RIG-I activity by RIG-I proteolysis
ontology: BP
definition:
OBSOLETE. The chemical reactions and pathways performed by a virus resulting in the hydrolysis of the host RIG-I protein (also known as DDX58) by cleavage of peptide bonds, thereby inhibiting RIG-I signal transduction.


go_id: GO:0039546
term: obsolete suppression by virus of host MAVS activity by MAVS proteolysis
ontology: BP
definition:
OBSOLETE. The chemical reactions and pathways performed by a virus resulting in the hydrolysis of the host MAVS (mitochondrial inhibitor of viral signaling) protein by cleavage of peptide bonds, thereby inhibiting the host innate immune response. For example, MAVS harbors a C-terminal transmembrane domain that targets it to the mitochondrial outer membrane; cleavage within this domain removes MAVS from the membrane, thus preventing it from signaling.


go_id: GO:0039549
term: obsolete suppression by virus of host IRF3 activity by inhibition of IRF3 phosphorylation
ontology: BP
definition:
OBSOLETE. Any process in which a virus stops, prevents, or reduces the rate or extent of the phosphorylation of IRF3 (interferon regulatory factor-3), thereby inhibiting IRF3 activation. In response to signaling from RIG-1/MDA-5 receptors, IRF3 is phosphorylated on multiple serine and threonine residues; phosphorylation results in the cytoplasm-to-nucleus translocation of IRF3, DNA binding, and increased transcriptional activation of interferon-encoding genes.


go_id: GO:0039550
term: obsolete suppression by virus of host IRF3 activity by inhibition of DNA binding
ontology: BP
definition:
OBSOLETE. Any process in which a virus stops, prevents, or reduces IRF3-dependent gene transcription, by preventing or reducing IRF3 binding to promoter sites.


go_id: GO:0039551
ontology: BP
term:
obsolete suppression by virus of host IRF3 activity by positive regulation of IRF3 catabolic process

definition:
OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of host IRF3 (interferon regulatory factor-3) by promoting the ubiquitin-dependent degradation of IRF3, mediated by the proteasome.


go_id: GO:0039555
term: obsolete suppression by virus of host MDA-5 activity via MDA-5 binding
ontology: BP
definition:
OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of MDA-5 (also known as IFIH1) by binding to MDA-5 itself. For example, direct binding of viral proteins to the host MDA-5 protein can inhibit interaction of MDA-5 with MAVS, its downstream signaling effector.


go_id: GO:0039558
term: obsolete suppression by virus of host IRF7 activity by positive regulation of IRF7 sumoylation
ontology: BP
definition:
OBSOLETE. Any process in which a virus stops, prevents, or reduces IRF7-dependent gene transcription, by promoting the sumoylation of IRF7, thereby disabling its activity.


go_id: GO:0039559
ontology: BP
term:
obsolete suppression by virus of host IRF7 activity by positive regulation of IRF7 catabolic process

definition:
OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of host IRF7 (interferon regulatory factor-7) by promoting the ubiquitin-dependent degradation of IRF7, mediated by the proteasome.


go_id: GO:0039561
ontology: BP
term:
obsolete suppression by virus of host IRF9 activity by positive regulation of IRF9 localization to nucleus

definition:
OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of host IRF9 (interferon regulatory factor-9) by promoting the nuclear accumulation of IRF9. For example, the reovirus mu2 protein promotes nuclear accumulation of host IRF9 by an as yet unconfirmed-mechanism.


go_id: GO:0039565
ontology: BP
term:
obsolete suppression by virus of host STAT1 activity by positive regulation of STAT1 catabolic process

definition:
OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of host STAT1 (signal transducer and activator of transcription-1) by promoting the ubiquitin-dependent degradation of STAT1, mediated by the proteasome.


go_id: GO:0039566
term: obsolete suppression by virus of host STAT1 activity by tyrosine dephosphorylation of STAT1
ontology: BP
definition:
OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT1 (signal transducer and activator of transcription-1) activity by the removal of phosphoric residues from STAT1-O-phospho-tyrosine to form STAT1-tyrosine. For example, the viral phosphatase VH1 dephosphorylates STAT1 to reverse STAT1 activation.


go_id: GO:0039567
ontology: BP
term:
obsolete suppression by virus of host STAT1 activity by negative regulation of STAT protein import into nucleus

definition:
OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT1 (signal transducer and activator of transcription-1) activity by retaining STAT1 in the cytoplasm, so STAT1 is unable to translocate to the nucleus to activate transcription of its target genes.


go_id: GO:0039568
term: obsolete suppression by virus of host STAT1 activity by inhibition of DNA binding
ontology: BP
definition:
OBSOLETE. Any process in which a virus stops, prevents, or reduces STAT1-dependent gene transcription, by preventing STAT1 from binding to promoter sites in the nucleus.


go_id: GO:0039569
ontology: BP
term:
obsolete suppression by virus of host STAT2 activity by positive regulation of STAT2 catabolic process

definition:
OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of host STAT2 (signal transducer and activator of transcription-2) by promoting the ubiquitin-dependent degradation of STAT2, mediated by the proteasome.


go_id: GO:0039570
ontology: BP
term:
obsolete suppression by virus of host STAT2 activity by negative regulation of STAT protein import into nucleus

definition:
OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT2 (signal transducer and activator of transcription-2) activity by retaining STAT2 in the cytoplasm, so STAT2 is unable to translocate to the nucleus to activate transcription of its target genes.


go_id: GO:0039571
ontology: BP
term:
obsolete suppression by virus of host STAT1 activity by negative regulation of STAT1 tyrosine phosphorylation

definition:
OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT1 (signal transducer and activator of transcription-1) activity by stopping, preventing, or reducing the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT1 protein. For example, the measles virus V protein inhibits tyrosine phosphorylation of STAT1, thereby preventing STAT1 activation.


go_id: GO:0039572
ontology: BP
term:
obsolete suppression by virus of host STAT2 activity by negative regulation of STAT2 tyrosine phosphorylation

definition:
OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT2 (signal transducer and activator of transcription-2) activity by stopping, preventing, or reducing the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT2 protein. For example, the measles virus V protein inhibits tyrosine phosphorylation of STAT2, thereby preventing STAT2 activation.


go_id: GO:0039575
ontology: BP
term:
obsolete suppression by virus of host TYK2 activity by negative regulation of TYK2 tyrosine phosphorylation

definition:
OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host TYK2 (tyrosine kinase 2) activity by stopping, preventing or reducing phosphorylation and thereby activation of TYK2.


go_id: GO:0039577
term: obsolete suppression by virus of host JAK1 activity by negative regulation of JAK1 phosphorylation
ontology: BP
definition:
OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host JAK1 (Janus Kinase 1) activity by stopping, preventing or reducing tyrosine phosphorylation of JAK1 and thereby activation of JAK1.


go_id: GO:0039578
term: obsolete suppression by virus of host JAK1 activity via JAK1 binding
ontology: BP
definition:
OBSOLETE.  Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host JAK1 (Janus Kinase 1) activity by interacting directly and selectively with JAK1. For example, the polyoma virus T antigen binds to JAK1 and renders it inactive.


go_id: GO:0039581
term: obsolete suppression by virus of host PKR activity via double-stranded RNA binding
ontology: BP
definition:
OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host PKR (protein kinase regulated by RNA) activity by binding to double-stranded RNA (dsRNA). Binding of viral proteins to RNA may sequester or alter the RNA so it can not be recognized by host PKR, or may compete with PKR for dsRNA binding.


go_id: GO:0039582
ontology: BP
term:
obsolete suppression by virus of host PKR activity by positive regulation of PKR nuclear localization

definition:
OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host PKR (protein kinase regulated by RNA) activity by promoting the localization of PKR in the nucleus. For example, human cytomegalovirus (HMCV) gene products directly interact with PKR and inhibit its activation by sequestering it in the nucleus, away from both its activator (cytoplasmic dsRNA) and its substrate, (eIF2alpha).


go_id: GO:0039583
term: obsolete suppression by virus of host PKR activity by positive regulation of PKR catabolic process
ontology: BP
definition:
OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host PKR (protein kinase regulated by RNA) activity by promoting the degradation of PKR via the proteosome. For example, the Rift Valley fever virus (RVFV) NSs protein induces the down-regulation of PKR by degradation through proteasomes.


go_id: GO:0039589
term: obsolete suppression by virus of host TAP complex
ontology: BP
definition:
OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of the host TAP complex, a heterodimer composed of the subunits TAP1 and TAP2 (transporter associated with antigen presentation). The TAP complex functions in the transport of antigenic peptides from the cytosol to the lumen of the endoplasmic reticulum, where they are loaded onto the MHC class I. By inhibiting the TAP complex, the virus prevents viral particles being presented at the cell surface, and thus evades the host immune response.


go_id: GO:0039597
term: obsolete induction by virus of host endoribonuclease activity
ontology: BP
definition:
OBSOLETE. Any viral process that activates or increases the frequency, rate or extent of host endoribonuclease activity.


go_id: GO:0039598
term: obsolete induction by virus of host nuclear polyadenylation-dependent mRNA catabolic process
ontology: BP
definition:
OBSOLETE. The process in which a virus increases the frequency, rate or extent of the breakdown of host messenger RNA (mRNA) initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target mRNA.


go_id: GO:0039603
ontology: MF
term:
obsolete TBP-class protein binding involved in viral suppression of host transcription initiation from RNA polymerase II promoter

definition:
OBSOLETE. Selective and non-covalent interaction of a viral protein with a member of the class of TATA-binding proteins (TBP) in the host, including any of the TBP-related factors (TRFs), which contributes to the viral-suppression of assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a host DNA template.


go_id: GO:0039605
ontology: MF
term:
obsolete TFIIB-class transcription factor binding involved in viral suppression of host transcription initiation from RNA polymerase II promoter

definition:
OBSOLETE. Selective and non-covalent interaction of a viral protein with a member of the TFIIB-class of host transcription factors, which contributes to the viral-suppression of assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a host DNA template.


go_id: GO:0039607
term: obsolete proteolysis by virus of host translation initiation factor
ontology: BP
definition:
OBSOLETE. The chemical reactions and pathways performed by a virus resulting in the hydrolysis of a host translation initiation factor by cleavage of its peptide bonds.


go_id: GO:0039608
ontology: BP
term:
obsolete suppression by virus of host translation initiation factor activity by induction of host protein dephosphorylation

definition:
OBSOLETE. Any process in which a virus prevents or reduces the frequency, rate or extent of activity of a host translation initiation factor by promoting dephosphorylation of a host protein.


go_id: GO:0039647
term: obsolete suppression by virus of host poly(A)-binding protein activity
ontology: BP
definition:
OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host poly(A)-binding protein (PABP) activity. PABP binds to the poly(A) tail of mRNA to facilitate translation.


