# go_term

go_id: GO:0060263
term: regulation of respiratory burst
ontology: BP
definition:
Any process that modulates the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.


go_id: GO:0060264
term: regulation of respiratory burst involved in inflammatory response
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.


go_id: GO:0060265
term: positive regulation of respiratory burst involved in inflammatory response
ontology: BP
definition:
Any process that increases the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.


go_id: GO:0060266
term: negative regulation of respiratory burst involved in inflammatory response
ontology: BP
definition:
Any process that decreases the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.


go_id: GO:0060267
term: positive regulation of respiratory burst
ontology: BP
definition:
Any process that increases the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.


go_id: GO:0060268
term: negative regulation of respiratory burst
ontology: BP
definition:
Any process that decreases the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.


go_id: GO:0060269
term: centripetally migrating follicle cell migration
ontology: BP
definition:
The cell migration process in which a follicle cell migrates as part of an epithelial sheet between the nurse cells and the oocyte. At the end of migration, they cover the anterior of the oocyte.


go_id: GO:0060270
term: main body follicle cell migration
ontology: BP
definition:
The ovarian follicle cell migration process in which follicle cells migrate posteriorly to form a columnar epithelium over the oocyte.


go_id: GO:0060271
term: cilium assembly
ontology: BP
definition:
The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.


go_id: GO:0060272
term: embryonic skeletal joint morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of skeletal joints are generated and organized during the embryonic phase. A skeletal joint is the connecting structure between the bones of the skeleton.


go_id: GO:0060273
term: crying behavior
ontology: BP
definition:
The behavior in which an organism sheds tears, often accompanied by non-verbal vocalizations and in response to external or internal stimuli.


go_id: GO:0060274
term: maintenance of stationary phase
ontology: BP
definition:
The homeostatic process in which a population of cells changes its metabolic activity resulting in the rate of death in the population equaling the rate of reproduction. Stationary phase can be in response to limited nutrients or a build-up of toxic substances in the environment.


go_id: GO:0060275
term: maintenance of stationary phase in response to starvation
ontology: BP
definition:
The homeostatic process in which a population of cells changes its metabolic activity resulting in the rate of death in the population equaling the rate of reproduction in response to limited nutrients in the environment.


go_id: GO:0060276
term: maintenance of stationary phase in response to toxin
ontology: BP
definition:
The homeostatic process in which a population of cells changes its metabolic activity resulting in the rate of death in the population equaling the rate of reproduction in response to a build-up of toxins in the environment.


go_id: GO:0060278
term: regulation of ovulation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary.


go_id: GO:0060279
term: positive regulation of ovulation
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary.


go_id: GO:0060280
term: negative regulation of ovulation
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary.


go_id: GO:0060281
term: regulation of oocyte development
ontology: BP
definition:
Any process that modulates the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.


go_id: GO:0060282
term: positive regulation of oocyte development
ontology: BP
definition:
Any process that increases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.


go_id: GO:0060283
term: negative regulation of oocyte development
ontology: BP
definition:
Any process that decreases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.


go_id: GO:0060284
term: regulation of cell development
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.


go_id: GO:0060285
term: cilium-dependent cell motility
ontology: BP
definition:
Cell motility due to the motion of one or more eukaryotic cilia. A eukaryotic cilium is a specialized organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.


go_id: GO:0060287
term: epithelial cilium movement involved in determination of left/right asymmetry
ontology: BP
definition:
The movement of cilia of epithelial cells of the Left Right Organizer (LRO), also referred to as the node in mouse or the Kupffer's vesicle in zebrafish, resulting in the leftward fluid flow across the LRO and generation or transport of a signal which determines asymmetry in an organism's body plan with respect to the left and right halves.


go_id: GO:0060288
term: formation of a compartment boundary
ontology: BP
definition:
Formation of a lineage restriction boundary within a developing tissue which does not correspond to some morphological barrier.


go_id: GO:0060289
term: compartment boundary maintenance
ontology: BP
definition:
A homeostatic process involved in the maintenance of a compartment boundary. A compartment boundary is a lineage restriction boundary within a developing tissue which does not correspond to some morphological barrier.


go_id: GO:0060290
term: transdifferentiation
ontology: BP
definition:
The conversion of a differentiated cell of one fate into a differentiated cell of another fate without first undergoing cell division or reversion to a more primitive or stem cell-like fate.


go_id: GO:0060291
term: long-term synaptic potentiation
ontology: BP
definition:
A process that modulates synaptic plasticity such that synapses are changed resulting in the increase in the rate, or frequency of synaptic transmission at the synapse.


go_id: GO:0060292
term: long-term synaptic depression
ontology: BP
definition:
A process that modulates synaptic plasticity such that synapses are changed resulting in the decrease in the rate, or frequency of synaptic transmission at the synapse.


go_id: GO:0060293
term: germ plasm
ontology: CC
definition:
Differentiated cytoplasm associated with a pole of an oocyte, egg or early embryo that will be inherited by the cells that will give rise to the germ line.


go_id: GO:0060295
term: regulation of cilium movement involved in cell motility
ontology: BP
definition:
Any process that modulates the rate frequency or extent of cilium movement involved in ciliary motility.


go_id: GO:0060297
term: regulation of sarcomere organization
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.


go_id: GO:0060298
term: positive regulation of sarcomere organization
ontology: BP
definition:
Any process that increases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.


go_id: GO:0060299
term: negative regulation of sarcomere organization
ontology: BP
definition:
Any process that decreases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.


go_id: GO:0060300
term: regulation of cytokine activity
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells.


go_id: GO:0060301
term: positive regulation of cytokine activity
ontology: BP
definition:
Any process that increases the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells.


go_id: GO:0060302
term: negative regulation of cytokine activity
ontology: BP
definition:
Any process that decreases the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells.


go_id: GO:0060304
term: regulation of phosphatidylinositol dephosphorylation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reaction involving the removal of one or more phosphate groups from a phosphatidylinositol.


go_id: GO:0060305
term: regulation of cell diameter
ontology: BP
definition:
Any process that modulates the diameter of a cell, the length of a line segment that crosses through the center of a circular section through a cell.


go_id: GO:0060306
term: regulation of membrane repolarization
ontology: BP
definition:
Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential, usually from positive to negative.


go_id: GO:0060307
term: regulation of ventricular cardiac muscle cell membrane repolarization
ontology: BP
definition:
Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential in a ventricular cardiomyocyte.


go_id: GO:0060308
term: GTP cyclohydrolase I regulator activity
ontology: MF
definition:
Binds to and modulates the activity of GTP cyclohydrolase I. GTP cyclohydrolase I activity catalyzes the reaction: GTP + 2 H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate.


go_id: GO:0060309
term: elastin catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of elastin. Elastin is a glycoprotein which is randomly coiled and crosslinked to form elastic fibers that are found in connective tissue.


go_id: GO:0060310
term: regulation of elastin catabolic process
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of elastin catabolism, the chemical reactions and pathways resulting in the breakdown of elastin.


go_id: GO:0060311
term: negative regulation of elastin catabolic process
ontology: BP
definition:
Any process that decreases the rate, frequency or extent of elastin catabolism, the chemical reactions and pathways resulting in the breakdown of elastin.


go_id: GO:0060312
term: regulation of blood vessel remodeling
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of blood vessel remodeling, the reorganization or renovation of existing blood vessels.


go_id: GO:0060313
term: negative regulation of blood vessel remodeling
ontology: BP
definition:
Any process that decreases the rate, frequency or extent of blood vessel remodeling, the reorganization or renovation of existing blood vessels.


go_id: GO:0060314
term: regulation of ryanodine-sensitive calcium-release channel activity
ontology: BP
definition:
Any process that modulates the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts.


go_id: GO:0060315
term: negative regulation of ryanodine-sensitive calcium-release channel activity
ontology: BP
definition:
Any process that decreases the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts.


go_id: GO:0060316
term: positive regulation of ryanodine-sensitive calcium-release channel activity
ontology: BP
definition:
Any process that increases the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts.


go_id: GO:0060317
term: cardiac epithelial to mesenchymal transition
ontology: BP
definition:
A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.


go_id: GO:0060320
term: rejection of self pollen
ontology: BP
definition:
The recognition and rejection of self pollen by cells in the stigma, mediated by the sharing and interaction of the single locus incompatibility haplotypes.


go_id: GO:0060321
term: acceptance of pollen
ontology: BP
definition:
The recognition and acceptance of pollen by cells in the stigma, mediated by the sharing and interaction of the single locus incompatibility haplotypes.


go_id: GO:0060322
term: head development
ontology: BP
definition:
The biological process whose specific outcome is the progression of a head from an initial condition to its mature state. The head is the anterior-most division of the body.


go_id: GO:0060323
term: head morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the head are generated and organized. The head is the anterior-most division of the body.


go_id: GO:0060324
term: face development
ontology: BP
definition:
The biological process whose specific outcome is the progression of a face from an initial condition to its mature state. The face is the ventral division of the head.


go_id: GO:0060325
term: face morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the face are generated and organized. The face is the ventral division of the head.


go_id: GO:0060326
term: cell chemotaxis
ontology: BP
definition:
The directed movement of a motile cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).


go_id: GO:0060327
term: cytoplasmic actin-based contraction involved in cell motility
ontology: BP
definition:
The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell from one place to another.


go_id: GO:0060328
term: cytoplasmic actin-based contraction involved in forward cell motility
ontology: BP
definition:
The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell in the direction that has been defined as the front of the cell.


go_id: GO:0060329
term: cytoplasmic actin-based contraction involved in rearward cell motility
ontology: BP
definition:
The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell in the direction that has been defined as the rear of the cell.


go_id: GO:0060330
term: regulation of response to interferon-gamma
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of a response to interferon-gamma. Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus.


go_id: GO:0060331
term: negative regulation of response to interferon-gamma
ontology: BP
definition:
Any process that decreases the rate, frequency or extent of a response to interferon-gamma. Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus.


go_id: GO:0060332
term: positive regulation of response to interferon-gamma
ontology: BP
definition:
Any process that increases the rate, frequency or extent of a response to interferon-gamma. Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus.


go_id: GO:0060333
term: interferon-gamma-mediated signaling pathway
ontology: BP
definition:
The series of molecular signals initiated by interferon-gamma binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Interferon gamma is the only member of the type II interferon found so far.


go_id: GO:0060334
term: regulation of interferon-gamma-mediated signaling pathway
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of an interferon-gamma-mediated signaling pathway.


go_id: GO:0060335
term: positive regulation of interferon-gamma-mediated signaling pathway
ontology: BP
definition:
Any process that increases the rate, frequency or extent of an interferon-gamma-mediated signaling pathway.


go_id: GO:0060336
term: negative regulation of interferon-gamma-mediated signaling pathway
ontology: BP
definition:
Any process that decreases the rate, frequency or extent of an interferon-gamma-mediated signaling pathway.


go_id: GO:0060337
term: type I interferon signaling pathway
ontology: BP
definition:
The series of molecular signals initiated by type I interferon binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.


go_id: GO:0060338
term: regulation of type I interferon-mediated signaling pathway
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of a type I interferon-mediated signaling pathway.


go_id: GO:0060339
term: negative regulation of type I interferon-mediated signaling pathway
ontology: BP
definition:
Any process that decreases the rate, frequency or extent of a type I interferon-mediated signaling pathway.


go_id: GO:0060340
term: positive regulation of type I interferon-mediated signaling pathway
ontology: BP
definition:
Any process that increases the rate, frequency or extent of a type I interferon-mediated signaling pathway.


go_id: GO:0060341
term: regulation of cellular localization
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of a process in which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell.


go_id: GO:0060342
term: photoreceptor inner segment membrane
ontology: CC
definition:
The membrane surrounding the inner segment of a vertebrate photoreceptor. The photoreceptor inner segment contains mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs.


go_id: GO:0060343
term: trabecula formation
ontology: BP
definition:
The process of creating a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue.


go_id: GO:0060344
term: liver trabecula formation
ontology: BP
definition:
The process of creating a trabecula in the liver. A trabecula is a tissue element in the form of a small beam, strut or rod.


go_id: GO:0060345
term: spleen trabecula formation
ontology: BP
definition:
The process of creating a trabecula in the spleen. A trabecula is a tissue element in the form of a small beam, strut or rod.


go_id: GO:0060346
term: bone trabecula formation
ontology: BP
definition:
The process of creating a trabecula in the bone. A trabecula is a tissue element in the form of a small beam, strut or rod.


go_id: GO:0060347
term: heart trabecula formation
ontology: BP
definition:
The process of creating a trabecula in the heart. A trabecula is a tissue element in the form of a small beam, strut or rod.


go_id: GO:0060348
term: bone development
ontology: BP
definition:
The process whose specific outcome is the progression of bone over time, from its formation to the mature structure. Bone is the hard skeletal connective tissue consisting of both mineral and cellular components.


go_id: GO:0060350
term: endochondral bone morphogenesis
ontology: BP
definition:
The process in which bones are generated and organized as a result of the conversion of initial cartilaginous anlage into bone.


go_id: GO:0060351
term: cartilage development involved in endochondral bone morphogenesis
ontology: BP
definition:
The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones.


go_id: GO:0060353
term: regulation of cell adhesion molecule production
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of cell adhesion molecule production. Cell adhesion molecule production is the appearance of a cell adhesion molecule as a result of its biosynthesis or a decrease in its catabolism.


go_id: GO:0060354
term: negative regulation of cell adhesion molecule production
ontology: BP
definition:
Any process that decreases the rate, frequency or extent of cell adhesion molecule production. Cell adhesion molecule production is the appearance of a cell adhesion molecule as a result of its biosynthesis or a decrease in its catabolism.


go_id: GO:0060355
term: positive regulation of cell adhesion molecule production
ontology: BP
definition:
Any process that increases the rate, frequency or extent of cell adhesion molecule production. Cell adhesion molecule production is the appearance of a cell adhesion molecule as a result of its biosynthesis or a decrease in its catabolism.


go_id: GO:0060357
term: regulation of leucine import
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of leucine import. Leucine import is the directed movement of leucine into a cell or organelle.


go_id: GO:0060358
term: negative regulation of leucine import
ontology: BP
definition:
Any process that decreases the rate, frequency or extent of leucine import. Leucine import is the directed movement of leucine into a cell or organelle.


go_id: GO:0060359
term: response to ammonium ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus.


go_id: GO:0060360
term: negative regulation of leucine import in response to ammonium ion
ontology: BP
definition:
Any process that decreases the rate, frequency or extent of leucine import as a result of an ammonium ion stimulus. Leucine import is the directed movement of leucine into a cell or organelle.


go_id: GO:0060361
term: flight
ontology: BP
definition:
Self-propelled movement of an organism from one location to another through the air, usually by means of active wing movement.


go_id: GO:0060362
term: flight involved in flight behavior
ontology: BP
definition:
Self-propelled movement of an organism from one location to another through the air that is part of the organism's response to external or internal stimuli resulting in flight.


go_id: GO:0060368
term: regulation of Fc receptor mediated stimulatory signaling pathway
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of the Fc receptor mediated stimulatory signaling pathway..


go_id: GO:0060369
term: positive regulation of Fc receptor mediated stimulatory signaling pathway
ontology: BP
definition:
Any process that increases the rate, frequency or extent of the Fc receptor mediated stimulatory signaling pathway.


go_id: GO:0060371
term: regulation of atrial cardiac muscle cell membrane depolarization
ontology: BP
definition:
Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in an atrial cardiomyocyte.


go_id: GO:0060372
term: regulation of atrial cardiac muscle cell membrane repolarization
ontology: BP
definition:
Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential in an atrial cardiomyocyte.


go_id: GO:0060373
term: regulation of ventricular cardiac muscle cell membrane depolarization
ontology: BP
definition:
Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in a ventricular cardiomyocyte.


go_id: GO:0060374
term: mast cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.


go_id: GO:0060375
term: regulation of mast cell differentiation
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.


go_id: GO:0060376
term: positive regulation of mast cell differentiation
ontology: BP
definition:
Any process that increases the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.


go_id: GO:0060377
term: negative regulation of mast cell differentiation
ontology: BP
definition:
Any process that decreases the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.


go_id: GO:0060378
term: regulation of brood size
ontology: BP
definition:
Any process that modulates brood size. Brood size is the number of progeny that survive embryogenesis and are cared for at one time.


go_id: GO:0060379
term: cardiac muscle cell myoblast differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a cardiac myoblast. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life.


go_id: GO:0060380
term: regulation of single-stranded telomeric DNA binding
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of binding to single-stranded telomeric DNA.


go_id: GO:0060382
term: regulation of DNA strand elongation
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of DNA strand elongation. DNA strand elongation is the DNA metabolic process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand.


go_id: GO:0060383
term: positive regulation of DNA strand elongation
ontology: BP
definition:
Any process that increases the rate, frequency or extent of DNA strand elongation. DNA strand elongation is the DNA metabolic process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand.


go_id: GO:0060384
term: innervation
ontology: BP
definition:
The process in which a nerve invades a tissue and makes functional synaptic connection within the tissue.


go_id: GO:0060385
term: axonogenesis involved in innervation
ontology: BP
definition:
The neurite development process that generates a long process of a neuron, as it invades a target tissue.


go_id: GO:0060387
term: fertilization envelope
ontology: CC
definition:
A structure that lies outside the plasma membrane and surrounds the egg. The fertilization envelope forms from the vitelline membrane after fertilization as a result of cortical granule release.


go_id: GO:0060388
term: vitelline envelope
ontology: CC
definition:
A glycoprotein-based structure that lies outside the plasma membrane and surrounds the egg before fertilization.


go_id: GO:0060389
term: pathway-restricted SMAD protein phosphorylation
ontology: BP
definition:
The process of introducing a phosphate group on to a pathway restricted SMAD protein. A pathway restricted SMAD protein is an effector protein that acts directly downstream of the transforming growth factor family receptor.


go_id: GO:0060390
term: regulation of SMAD protein signal transduction
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of SMAD protein signal transduction. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.


go_id: GO:0060391
term: positive regulation of SMAD protein signal transduction
ontology: BP
definition:
Any process that increases the rate, frequency or extent of SMAD protein signal transduction. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.


go_id: GO:0060392
term: negative regulation of SMAD protein signal transduction
ontology: BP
definition:
Any process that decreases the rate, frequency or extent of the SMAD protein signaling pathway. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.


go_id: GO:0060393
term: regulation of pathway-restricted SMAD protein phosphorylation
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of pathway-restricted SMAD protein phosphorylation. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.


go_id: GO:0060394
term: negative regulation of pathway-restricted SMAD protein phosphorylation
ontology: BP
definition:
Any process that decreases the rate, frequency or extent of pathway-restricted SMAD protein phosphorylation. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.


go_id: GO:0060395
term: SMAD protein signal transduction
ontology: BP
definition:
The cascade of processes by which a signal interacts with a receptor, causing a change in the activity of a SMAD protein, and ultimately effecting a change in the functioning of the cell.


go_id: GO:0060396
term: growth hormone receptor signaling pathway
ontology: BP
definition:
The series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand.


go_id: GO:0060397
term: growth hormone receptor signaling pathway via JAK-STAT
ontology: BP
definition:
The process in which STAT proteins (Signal Transducers and Activators of Transcription) are activated by members of the JAK (janus activated kinase) family of tyrosine kinases, following the binding of physiological ligands to the growth hormone receptor. Once activated, STATs dimerize and translocate to the nucleus and modulate the expression of target genes.


go_id: GO:0060398
term: regulation of growth hormone receptor signaling pathway
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand.


go_id: GO:0060399
term: positive regulation of growth hormone receptor signaling pathway
ontology: BP
definition:
Any process that increases the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand.


go_id: GO:0060400
term: negative regulation of growth hormone receptor signaling pathway
ontology: BP
definition:
Any process that decreases the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand.


go_id: GO:0060404
term: axonemal microtubule depolymerization
ontology: BP
definition:
The removal of tubulin heterodimers from one or both ends of an axonemal microtubule. An axonemal microtubule is a microtubule in the axoneme of a cilium or flagellum; an axoneme contains nine modified doublet microtubules surrounding a pair of single microtubules.


go_id: GO:0060405
term: regulation of penile erection
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow.


go_id: GO:0060406
term: positive regulation of penile erection
ontology: BP
definition:
Any process that increases the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow.


go_id: GO:0060407
term: negative regulation of penile erection
ontology: BP
definition:
Any process that stops, prevents, or reduces the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow.


go_id: GO:0060408
term: regulation of acetylcholine metabolic process
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.


go_id: GO:0060409
term: positive regulation of acetylcholine metabolic process
ontology: BP
definition:
Any process that increases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.


go_id: GO:0060410
term: negative regulation of acetylcholine metabolic process
ontology: BP
definition:
Any process that decreases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.


go_id: GO:0060411
term: cardiac septum morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of a cardiac septum is generated and organized. A cardiac septum is a partition that separates parts of the heart.


go_id: GO:0060412
term: ventricular septum morphogenesis
ontology: BP
definition:
The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another.


go_id: GO:0060413
term: atrial septum morphogenesis
ontology: BP
definition:
The developmental process in which atrial septum is generated and organized. The atrial septum separates the upper chambers (the atria) of the heart from one another.


go_id: GO:0060414
term: aorta smooth muscle tissue morphogenesis
ontology: BP
definition:
The process in which the structure of the smooth muscle tissue surrounding the aorta is generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body.


go_id: GO:0060415
term: muscle tissue morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of muscle tissue are generated and organized. Muscle tissue consists of a set of cells that are part of an organ and carry out a contractive function.


go_id: GO:0060416
term: response to growth hormone
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone stimulus. Growth hormone is a peptide hormone that binds to the growth hormone receptor and stimulates growth.


go_id: GO:0060418
term: yolk plasma
ontology: CC
definition:
Discrete structures that partition the water-soluble portion of the yolk of oocytes and ova, which may or may not be membrane enclosed.


go_id: GO:0060420
term: regulation of heart growth
ontology: BP
definition:
Any process that modulates the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart.


go_id: GO:0060421
term: positive regulation of heart growth
ontology: BP
definition:
Any process that increases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart.


go_id: GO:0060422
term: peptidyl-dipeptidase inhibitor activity
ontology: MF
definition:
Binds to and stops, prevents or reduces the activity of a peptidyl-dipeptidase. Peptidyl-dipeptidase activity catalyzes the release of C-terminal dipeptides from a polypeptide chain.


go_id: GO:0060423
term: foregut regionalization
ontology: BP
definition:
The pattern specification process that results in the spatial subdivision of an axis or axes along the foregut to define an area or volume in which specific patterns of cell differentiation will take place.


go_id: GO:0060424
term: lung field specification
ontology: BP
definition:
The process that results in the delineation of a specific region of the foregut into the area in which the lung will develop.


go_id: GO:0060426
term: lung vasculature development
ontology: BP
definition:
The biological process whose specific outcome is the progression of a lung vasculature from an initial condition to its mature state. This process begins with the formation of the lung vasculature and ends with the mature structure. The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs.


go_id: GO:0060427
term: lung connective tissue development
ontology: BP
definition:
The biological process whose specific outcome is the progression of lung connective tissue from an initial condition to its mature state. This process begins with the formation of lung connective tissue and ends with the mature structure. The lung connective tissue is a material made up of fibers forming a framework and support structure for the lungs.


go_id: GO:0060428
term: lung epithelium development
ontology: BP
definition:
The biological process whose specific outcome is the progression of the lung epithelium from an initial condition to its mature state. This process begins with the formation of lung epithelium and ends with the mature structure. The lung epithelium is the specialized epithelium that lines the inside of the lung.


go_id: GO:0060429
term: epithelium development
ontology: BP
definition:
The process whose specific outcome is the progression of an epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.


go_id: GO:0060430
term: lung saccule development
ontology: BP
definition:
The biological process whose specific outcome is the progression of a lung saccule from an initial condition to its mature state. The lung saccule is the primitive gas exchange portion of the lung composed of type I and type II cells.


go_id: GO:0060431
term: primary lung bud formation
ontology: BP
definition:
The morphogenetic process in which the foregut region specified to become the lung forms the initial left and right buds.


go_id: GO:0060432
term: lung pattern specification process
ontology: BP
definition:
Any developmental process that results in the creation of defined areas or spaces within the lung, to which cells respond and eventually are instructed to differentiate.


go_id: GO:0060433
term: bronchus development
ontology: BP
definition:
The biological process whose specific outcome is the progression of a bronchus from an initial condition to its mature state. This process begins with the formation of the bronchus and ends with the mature structure. The bronchus is the portion of the airway that connects to the lungs.


go_id: GO:0060434
term: bronchus morphogenesis
ontology: BP
definition:
The process in which the bronchus is generated and organized. The bronchus is the portion of the airway that connects to the lungs.


go_id: GO:0060435
term: bronchiole development
ontology: BP
definition:
The biological process whose specific outcome is the progression of a bronchiole from an initial condition to its mature state. This process begins with the formation of the bronchiole and ends with the mature structure. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi.


go_id: GO:0060436
term: bronchiole morphogenesis
ontology: BP
definition:
The process in which a bronchiole is generated and organized. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi.


go_id: GO:0060437
term: lung growth
ontology: BP
definition:
The increase in size or mass of a lung. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax.


go_id: GO:0060438
term: trachea development
ontology: BP
definition:
The process whose specific outcome is the progression of a trachea over time, from its formation to the mature structure. The trachea is the portion of the airway that attaches to the bronchi as it branches.


go_id: GO:0060439
term: trachea morphogenesis
ontology: BP
definition:
The process in which a trachea is generated and organized. The trachea is the portion of the airway that attaches to the bronchi as it branches.


go_id: GO:0060440
term: trachea formation
ontology: BP
definition:
The process pertaining to the initial formation of a trachea from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the trachea is recognizable. The trachea is the portion of the airway that attaches to the bronchi as it branches.


go_id: GO:0060441
term: epithelial tube branching involved in lung morphogenesis
ontology: BP
definition:
The process in which a highly ordered sequence of patterning events generates the branched epithelial tubes of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.


go_id: GO:0060442
term: branching involved in prostate gland morphogenesis
ontology: BP
definition:
The process in which the branching structure of the prostate gland is generated and organized. A branch is a division or offshoot from a main stem.


go_id: GO:0060443
term: mammary gland morphogenesis
ontology: BP
definition:
The process in which anatomical structures of the mammary gland are generated and organized. Morphogenesis refers to the creation of shape. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.


go_id: GO:0060444
term: branching involved in mammary gland duct morphogenesis
ontology: BP
definition:
The process in which the branching structure of the mammary gland duct is generated and organized. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.


go_id: GO:0060446
term: branching involved in open tracheal system development
ontology: BP
definition:
The process in which the anatomical structures of branches in the open tracheal system are generated and organized.


go_id: GO:0060450
term: positive regulation of hindgut contraction
ontology: BP
definition:
Any process that increases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine.


go_id: GO:0060451
term: negative regulation of hindgut contraction
ontology: BP
definition:
Any process that decreases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine.


go_id: GO:0060453
term: regulation of gastric acid secretion
ontology: BP
definition:
Any process that modulates the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion.


go_id: GO:0060454
term: positive regulation of gastric acid secretion
ontology: BP
definition:
Any process that increases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion.


go_id: GO:0060455
term: negative regulation of gastric acid secretion
ontology: BP
definition:
Any process that decreases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion.


go_id: GO:0060456
term: positive regulation of digestive system process
ontology: BP
definition:
Any process that increases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.


go_id: GO:0060457
term: negative regulation of digestive system process
ontology: BP
definition:
Any process that decreases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.


go_id: GO:0060458
term: right lung development
ontology: BP
definition:
The biological process whose specific outcome is the progression of a right lung from an initial condition to its mature state. This process begins with the formation of the right lung and ends with the mature structure. The right lung is the lung which is on the right side of the anterior posterior axis looking from a dorsal to ventral aspect.


go_id: GO:0060459
term: left lung development
ontology: BP
definition:
The biological process whose specific outcome is the progression of a left lung from an initial condition to its mature state. This process begins with the formation of the left lung and ends with the mature structure. The left lung is the lung which is on the left side of the anterior posterior axis looking from a dorsal to ventral aspect.


go_id: GO:0060462
term: lung lobe development
ontology: BP
definition:
The biological process whose specific outcome is the progression of a lung lobe from an initial condition to its mature state. This process begins with the formation of a lung lobe by branching morphogenesis and ends with the mature structure. A lung lobe is one of the rounded projections that compose the lung.


go_id: GO:0060463
term: lung lobe morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of a lung lobe are generated and organized. A lung lobe is a projection that extends from the lung.


go_id: GO:0060464
term: lung lobe formation
ontology: BP
definition:
The developmental process pertaining to the initial formation of a lung lobe from unspecified parts. This process begins with the specific processes that contribute to the appearance of the lobe and ends when the structural rudiment is recognizable. A lung lobe is a projection that extends from the lung.


go_id: GO:0060465
term: pharynx development
ontology: BP
definition:
The biological process whose specific outcome is the progression of a pharynx from an initial condition to its mature state. The pharynx is the part of the digestive system immediately posterior to the mouth.


go_id: GO:0060466
term: activation of meiosis involved in egg activation
ontology: BP
definition:
Any process that starts the inactive process of meiosis in an egg after the egg has been fertilized or physiologically activated. Eggs generally arrest in meiosis and complete the process after activation.


go_id: GO:0060467
term: negative regulation of fertilization
ontology: BP
definition:
Any process that decreases the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).


go_id: GO:0060468
term: prevention of polyspermy
ontology: BP
definition:
The negative regulation of fertilization process that takes place as part of egg activation, ensuring that only a single sperm fertilizes the egg.


go_id: GO:0060470
term: positive regulation of cytosolic calcium ion concentration involved in egg activation
ontology: BP
definition:
The process that increases the concentration of calcium ions in the cytosol after fertilization or the physiological activation of an egg.


go_id: GO:0060471
term: cortical granule exocytosis
ontology: BP
definition:
The process of secretion by a cell that results in the release of intracellular molecules contained within a cortical granule by fusion of the vesicle with the plasma membrane of a cell. A cortical granule is a specialized secretory vesicle that is released during egg activation that changes the surface of the egg to prevent polyspermy.


go_id: GO:0060472
ontology: BP
term:
positive regulation of cortical granule exocytosis by positive regulation of cytosolic calcium ion concentration

definition:
Any process that activates or increases the frequency, rate or extent of cortical granule exocytosis by directing movement of calcium ions (Ca2+) into the cytosol.


go_id: GO:0060473
term: cortical granule
ontology: CC
definition:
A secretory vesicle that is stored under the cell membrane of an egg. These vesicles fuse with the egg plasma membrane as part of egg activation and are part of the block to polyspermy.


go_id: GO:0060474
term: positive regulation of flagellated sperm motility involved in capacitation
ontology: BP
definition:
The process in which the controlled movement of a flagellated sperm cell is initiated as part of the process required for flagellated sperm to reach fertilization competence.


go_id: GO:0060475
term: positive regulation of actin filament polymerization involved in acrosome reaction
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of actin polymerization as part of the acrosome reaction.


go_id: GO:0060476
term: protein localization involved in acrosome reaction
ontology: BP
definition:
The actin-based process in which a protein is transported to, or maintained in, a specific location in the sperm as part of the acrosome reaction.


go_id: GO:0060478
term: acrosomal vesicle exocytosis
ontology: BP
definition:
The calcium ion regulated exocytosis which results in fusion of the acrosomal vesicle with the plasma membrane of the sperm as part of the acrosome reaction.


go_id: GO:0060479
term: lung cell differentiation
ontology: BP
definition:
The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate.


go_id: GO:0060480
term: lung goblet cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a lung goblet cell. A goblet cell is a cell of the epithelial lining that produces and secretes mucins.


go_id: GO:0060481
term: lobar bronchus epithelium development
ontology: BP
definition:
The biological process whose specific outcome is the progression of a lobar bronchus epithelium from an initial condition to its mature state. This process begins with the formation of the lobar bronchus epithelium and ends with the mature structure. The lobar bronchus epithelium is the tissue made up of epithelial cells that lines the inside of the lobar bronchus.


go_id: GO:0060482
term: lobar bronchus development
ontology: BP
definition:
The biological process whose specific outcome is the progression of a lobar bronchus from an initial condition to its mature state. This process begins with the formation of the lobar bronchus and ends with the mature structure. The lobar bronchus is the major airway within the respiratory tree that starts by division of the principal bronchi on both sides and ends at the point of its own subdivision into tertiary or segmental bronchi.


go_id: GO:0060483
term: lobar bronchus mesenchyme development
ontology: BP
definition:
The biological process whose specific outcome is the progression of a lobar bronchus mesenchyme from an initial condition to its mature state. This process begins with the formation of the lobar bronchus mesenchyme and ends with the mature structure. The lobar bronchus mesenchyme is the mass of tissue composed of mesenchymal cells in the lobar bronchus.


go_id: GO:0060484
term: lung-associated mesenchyme development
ontology: BP
definition:
The biological process whose specific outcome is the progression of a lung-associated mesenchyme from an initial condition to its mature state. This process begins with the formation of lung-associated mesenchyme and ends with the mature structure. Lung-associated mesenchyme is the tissue made up of loosely connected mesenchymal cells in the lung.


go_id: GO:0060485
term: mesenchyme development
ontology: BP
definition:
The process whose specific outcome is the progression of a mesenchymal tissue over time, from its formation to the mature structure. A mesenchymal tissue is made up of loosely packed stellate cells.


go_id: GO:0060486
term: club cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a club cell. A club cell is an unciliated epithelial cell found in the respiratory and terminal bronchioles.


go_id: GO:0060487
term: lung epithelial cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell that contributes to the epithelium of the lung.


go_id: GO:0060492
term: lung induction
ontology: BP
definition:
The close range interaction of two or more cells or tissues that causes the cells of the foregut to change their fates and specify the development of the lung.


go_id: GO:0060493
term: mesenchymal-endodermal cell signaling involved in lung induction
ontology: BP
definition:
Any process that mediates the transfer of information from a mesenchymal cell to an endodermal cell in the foregut and contributes to the formation of the lung bud.


go_id: GO:0060494
term: inductive mesenchymal-endodermal cell signaling
ontology: BP
definition:
Any process that mediates the transfer of information from a mesenchymal cell to an endodermal cell changing the fate of the endodermal cell.


go_id: GO:0060495
term: cell-cell signaling involved in lung development
ontology: BP
definition:
Any process that mediates the transfer of information from one cell to another and contributes to the progression of the lung, from its initial state to the mature structure.


go_id: GO:0060496
term: mesenchymal-epithelial cell signaling involved in lung development
ontology: BP
definition:
Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell and contributes to the development of the lung.


go_id: GO:0060497
term: mesenchymal-endodermal cell signaling
ontology: BP
definition:
Any process that mediates the transfer of information between a mesenchymal cell and an endodermal cell.


go_id: GO:0060498
term: retinoic acid receptor signaling pathway involved in lung bud formation
ontology: BP
definition:
The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands contributing to the formation of the primary lung bud.


go_id: GO:0060499
term: fibroblast growth factor receptor signaling pathway involved in lung induction
ontology: BP
definition:
The series of molecular signals generated as a consequence of a fibroblast growth factor-type receptor binding to one of its physiological ligands resulting in the formation of the lung bud along the lateral-esophageal sulcus.


go_id: GO:0060501
term: positive regulation of epithelial cell proliferation involved in lung morphogenesis
ontology: BP
definition:
Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung attaining its shape.


go_id: GO:0060502
term: epithelial cell proliferation involved in lung morphogenesis
ontology: BP
definition:
The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the lung.


go_id: GO:0060504
term: positive regulation of epithelial cell proliferation involved in lung bud dilation
ontology: BP
definition:
Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung bud increasing in size radially.


go_id: GO:0060505
term: epithelial cell proliferation involved in lung bud dilation
ontology: BP
definition:
The multiplication or reproduction of epithelial cells that contribute to the radial growth of a lung bud.


go_id: GO:0060506
term: smoothened signaling pathway involved in lung development
ontology: BP
definition:
The series of molecular signals generated as a consequence of activation of the transmembrane Smoothened-type protein. This process contributes to lung development.


go_id: GO:0060507
term: epidermal growth factor receptor signaling pathway involved in lung development
ontology: BP
definition:
The series of molecular signals generated as a consequence of an epidermal growth factor-type receptor binding to one of its physiological ligands. This process contributes to lung development.


go_id: GO:0060508
term: lung basal cell differentiation
ontology: BP
definition:
The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature basal cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate. A basal cell is an epithelial stem cell.


go_id: GO:0060509
term: type I pneumocyte differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a type I pneumocyte. A type I pneumocyte is a flattened cell with greatly attenuated cytoplasm and a paucity of organelles.


go_id: GO:0060510
term: type II pneumocyte differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a type II pneumocyte. A type II pneumocyte is a surfactant secreting cell that contains abundant cytoplasm containing numerous lipid-rich multilamellar bodies.


go_id: GO:0060511
term: creation of an inductive signal by a mesenchymal cell involved in lung induction
ontology: BP
definition:
The process in which splanchnic mesenchymal cells send a signal over a short range to endodermal cells inducing them to form the primary lung bud.


go_id: GO:0060513
term: prostatic bud formation
ontology: BP
definition:
The morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth.


go_id: GO:0060514
term: prostate induction
ontology: BP
definition:
The close range interaction of the urogenital sinus mesenchyme and the urogenital sinus epithelium that causes the cells of the urogenital sinus epithelium to change their fates and specify the development of the prostate gland.


go_id: GO:0060515
term: prostate field specification
ontology: BP
definition:
The process that results in the delineation of a specific region of the urogenital sinus epithelium into the area in which the prostate gland will develop.


go_id: GO:0060518
term: cell migration involved in prostatic bud elongation
ontology: BP
definition:
The orderly movement of epithelial cells from one site to another contributing to the elongation of the primary prostatic bud.


go_id: GO:0060519
term: cell adhesion involved in prostatic bud elongation
ontology: BP
definition:
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the elongation of the primary prostatic bud.


go_id: GO:0060520
term: activation of prostate induction by androgen receptor signaling pathway
ontology: BP
definition:
The series of molecular signals initiated by androgen binding to its receptor in the urogenital sinus mesenchyme that initiates prostate induction. Prostate induction is the close range interaction of the urogenital sinus mesenchyme and the urogenital sinus epithelium that causes the cells of the urogenital sinus epithelium to change their fates and specify the development of the prostate gland.


go_id: GO:0060521
term: mesenchymal-epithelial cell signaling involved in prostate induction
ontology: BP
definition:
Signaling at short range from urogenital sinus mesenchymal cells to cells of the urogenital epithelium resulting in the epithelial cells adopting a prostatic fate.


go_id: GO:0060522
term: inductive mesenchymal to epithelial cell signaling
ontology: BP
definition:
Signaling at short range from mesenchymal cells to cells of an epithelium that results in a developmental change in the epithelial cells.


go_id: GO:0060525
term: prostate glandular acinus development
ontology: BP
definition:
The progression of a glandular acinus of the prostate gland over time, from its initial formation to the mature structure. The glandular acini are the saclike structures of the gland.


go_id: GO:0060526
term: prostate glandular acinus morphogenesis
ontology: BP
definition:
The process in which the prostate glandular acini are generated and organized. The glandular acini are the saclike structures of the gland.


go_id: GO:0060527
term: prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis
ontology: BP
definition:
The branching morphogenesis process in which the prostate epithelial cords branch freely to create the structure of the prostate acini.


go_id: GO:0060528
ontology: BP
term:
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development

definition:
The process in which a relatively unspecialized epithelial cell acquires specialized features of a secretory columnal luminar epithelial cell of the prostate.


go_id: GO:0060529
term: squamous basal epithelial stem cell differentiation involved in prostate gland acinus development
ontology: BP
definition:
The process in which a relatively unspecialized epithelial cell acquires specialized features of a squamous basal epithelial stem cell of the prostate.


go_id: GO:0060530
term: smooth muscle cell differentiation involved in prostate glandular acinus development
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the prostate glandular acinus.


go_id: GO:0060531
term: neuroendocrine cell differentiation involved in prostate gland acinus development
ontology: BP
definition:
The process in which relatively unspecialized cells acquires specialized structural and functions of a neuroendocrine cell of the prostate gland acinus.


go_id: GO:0060532
term: bronchus cartilage development
ontology: BP
definition:
The process whose specific outcome is the progression of lung cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.


go_id: GO:0060533
term: bronchus cartilage morphogenesis
ontology: BP
definition:
The process in which the bronchus cartilage is generated and organized. The bronchus cartilage is the connective tissue of the portion of the airway that connects to the lungs.


go_id: GO:0060534
term: trachea cartilage development
ontology: BP
definition:
The process whose specific outcome is the progression of the tracheal cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.


go_id: GO:0060535
term: trachea cartilage morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of cartilage in the trachea are generated and organized.


go_id: GO:0060537
term: muscle tissue development
ontology: BP
definition:
The progression of muscle tissue over time, from its initial formation to its mature state. Muscle tissue is a contractile tissue made up of actin and myosin fibers.


go_id: GO:0060538
term: skeletal muscle organ development
ontology: BP
definition:
The progression of a skeletal muscle organ over time from its initial formation to its mature state. A skeletal muscle organ includes the skeletal muscle tissue and its associated connective tissue.


go_id: GO:0060539
term: diaphragm development
ontology: BP
definition:
The progression of the diaphragm over time from its initial formation to the mature structure. The diaphragm is a skeletal muscle that is responsible for contraction and expansion of the lungs.


go_id: GO:0060541
term: respiratory system development
ontology: BP
definition:
The progression of the respiratory system over time from its formation to its mature structure. The respiratory system carries out respiratory gaseous exchange.


go_id: GO:0060542
term: regulation of strand invasion
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules.


go_id: GO:0060543
term: negative regulation of strand invasion
ontology: BP
definition:
Any process that decreases the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules.


go_id: GO:0060544
term: regulation of necroptotic process
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors.


go_id: GO:0060545
term: positive regulation of necroptotic process
ontology: BP
definition:
Any process that increases the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors.


go_id: GO:0060546
term: negative regulation of necroptotic process
ontology: BP
definition:
Any process that decreases the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors.


go_id: GO:0060547
term: negative regulation of necrotic cell death
ontology: BP
definition:
Any process that decreases the rate, frequency or extent of necrotic cell death. Necrotic cell death is a cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents.


go_id: GO:0060548
term: negative regulation of cell death
ontology: BP
definition:
Any process that decreases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.


go_id: GO:0060549
term: regulation of fructose 1,6-bisphosphate 1-phosphatase activity
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of fructose 1,6-bisphosphate 1-phosphatase activity. Fructose 1,6-bisphosphate 1-phosphatase activity is the catalysis of the reaction: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate.


go_id: GO:0060550
term: positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity
ontology: BP
definition:
Any process that increases the rate, frequency or extent of fructose 1,6-bisphosphate 1-phosphatase activity. Fructose 1,6-bisphosphate 1-phosphatase activity is the catalysis of the reaction: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate.


go_id: GO:0060551
term: regulation of fructose 1,6-bisphosphate metabolic process
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of fructose 1,6-bisphosphate metabolism. Fructose 1,6-bisphosphate metabolism is the chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis.


go_id: GO:0060552
term: positive regulation of fructose 1,6-bisphosphate metabolic process
ontology: BP
definition:
Any process that increases the rate, frequency or extent of fructose 1,6-bisphosphate metabolism. Fructose 1,6-bisphosphate metabolism is the chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis.


go_id: GO:0060556
term: regulation of vitamin D biosynthetic process
ontology: BP
definition:
Any process that modulates the rate frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).


go_id: GO:0060557
term: positive regulation of vitamin D biosynthetic process
ontology: BP
definition:
Any process that increases the rate, frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).


go_id: GO:0060558
term: regulation of calcidiol 1-monooxygenase activity
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O.


go_id: GO:0060559
term: positive regulation of calcidiol 1-monooxygenase activity
ontology: BP
definition:
Any process that increases the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is the catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O.


go_id: GO:0060560
term: developmental growth involved in morphogenesis
ontology: BP
definition:
The increase in size or mass of an anatomical structure that contributes to the structure attaining its shape.


go_id: GO:0060562
term: epithelial tube morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of a tube are generated and organized from an epithelium. Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system.


go_id: GO:0060566
term: positive regulation of termination of DNA-templated transcription
ontology: BP
definition:
Any process that increases the rate, frequency or extent of DNA-templated transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA.


go_id: GO:0060567
term: negative regulation of termination of DNA-templated transcription
ontology: BP
definition:
Any process that decreases the rate, frequency or extent of DNA-dependent transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA.


go_id: GO:0060568
term: regulation of peptide hormone processing
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone.


go_id: GO:0060569
term: positive regulation of peptide hormone processing
ontology: BP
definition:
Any process that increases the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone.


go_id: GO:0060570
term: negative regulation of peptide hormone processing
ontology: BP
definition:
Any process that decreases the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone.


go_id: GO:0060572
term: morphogenesis of an epithelial bud
ontology: BP
definition:
The morphogenetic process in which a bud forms from an epithelial sheet. A bud is a protrusion that forms form the sheet by localized folding.


go_id: GO:0060573
term: cell fate specification involved in pattern specification
ontology: BP
definition:
The process involved in the specification of the identity of a cell in a field of cells that is being instructed as to how to differentiate. Once specification has taken place, that cell will be committed to differentiate down a specific pathway if left in its normal environment.


go_id: GO:0060574
term: intestinal epithelial cell maturation
ontology: BP
definition:
The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell of the intestine to attain its fully functional state. A columnar/cuboidal epithelial cell of the intestine mature as they migrate from the intestinal crypt to the villus.


go_id: GO:0060575
term: intestinal epithelial cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell of the intestine.


go_id: GO:0060576
term: intestinal epithelial cell development
ontology: BP
definition:
The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell of the intestine over time, from its formation to the mature structure.


go_id: GO:0060577
term: pulmonary vein morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the pulmonary venous blood vessels are generated and organized. Pulmonary veins are blood vessels that transport blood from the lungs to the heart.


go_id: GO:0060578
term: superior vena cava morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of superior vena cava generated and organized. The superior vena cava is a blood vessel that transports blood from the upper body to the heart.


go_id: GO:0060579
term: ventral spinal cord interneuron fate commitment
ontology: BP
definition:
The process in which the developmental fate of a cell becomes restricted such that it will develop into a ventral spinal cord interneuron. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses.


go_id: GO:0060580
term: ventral spinal cord interneuron fate determination
ontology: BP
definition:
The process in which a cell becomes capable of differentiating autonomously into a ventral spinal cord interneuron regardless of its environment; upon determination, the cell fate cannot be reversed. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses.


go_id: GO:0060581
term: cell fate commitment involved in pattern specification
ontology: BP
definition:
The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells within a field of cells that will exhibit a certain pattern of differentiation. Positional information is established through protein signals that emanate from a localized source within a developmental field resulting in specification of a cell type. Those signals are then interpreted in a cell-autonomous manner resulting in the determination of the cell type.


go_id: GO:0060582
term: cell fate determination involved in pattern specification
ontology: BP
definition:
A process involved in commitment of a cell to a fate in a developmental field. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.


go_id: GO:0060583
term: regulation of actin cortical patch localization
ontology: BP
definition:
Any process that modulates the localization of an actin cortical patch. An actin cortical patch is a discrete actin-containing structure found just beneath the plasma membrane in fungal cells.


go_id: GO:0060584
term: regulation of prostaglandin-endoperoxide synthase activity
ontology: BP
definition:
Any process that modulates the rate, frequency or prostaglandin-endoperoxide synthase activity. Prostaglandin-endoperoxide synthase activity is the catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O.


go_id: GO:0060585
term: positive regulation of prostaglandin-endoperoxide synthase activity
ontology: BP
definition:
Any process that increases the rate, frequency or extent of prostaglandin-endoperoxide synthase activity. Prostaglandin-endoperoxide synthase activity is the catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O.


go_id: GO:0060586
term: multicellular organismal iron ion homeostasis
ontology: BP
definition:
Any process involved in the maintenance of the distribution of iron stores within tissues and organs of a multicellular organism.


go_id: GO:0060587
term: regulation of lipoprotein lipid oxidation
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of lipoprotein lipid oxidation. Lipoprotein lipid oxidation is the modification of a lipoprotein by oxidation of the lipid group.


go_id: GO:0060588
term: negative regulation of lipoprotein lipid oxidation
ontology: BP
definition:
Any process that decreases the rate, frequency or extent of lipoprotein lipid oxidation. Lipoprotein lipid oxidation is the modification of a lipoprotein by oxidation of the lipid group.


go_id: GO:0060591
term: chondroblast differentiation
ontology: BP
definition:
The process in which a mesenchymal cell, acquires specialized structural and/or functional features of a chondroblast. Differentiation includes the processes involved in commitment of a cell to a chondroblast fate. A chondroblast is a precursor cell to chondrocytes.


go_id: GO:0060592
term: mammary gland formation
ontology: BP
definition:
The process pertaining to the initial formation of the mammary gland from unspecified parts. The process begins with formation of the mammary line and ends when the solid mammary bud invades the primary mammary mesenchyme.


go_id: GO:0060593
term: Wnt signaling pathway involved in mammary gland specification
ontology: BP
definition:
The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of a cell in the epidermis resulting in the formation of the mammary line. The mammary line is a ridge of epidermal cells that will form the mammary placodes.


go_id: GO:0060594
term: mammary gland specification
ontology: BP
definition:
The regionalization process in which the mammary line is specified. The mammary line is a ridge of epidermal cells that will form the mammary placodes.


go_id: GO:0060595
term: fibroblast growth factor receptor signaling pathway involved in mammary gland specification
ontology: BP
definition:
The series of molecular signals initiated by binding of a fibroblast growth factor to its receptor on the surface of al cell in the epidermis resulting in the formation of the mammary line. The mammary line is a ridge of epidermal cells that will form the mammary placodes.


go_id: GO:0060596
term: mammary placode formation
ontology: BP
definition:
The developmental process in which the mammary placode forms. The mammary placode is a transient lens shaped structure that will give rise to the mammary bud proper.


go_id: GO:0060603
term: mammary gland duct morphogenesis
ontology: BP
definition:
The process in which anatomical structures of the mammary ducts are generated and organized. Mammary ducts are epithelial tubes that transport milk.


go_id: GO:0060606
term: tube closure
ontology: BP
definition:
Creation of the central hole of a tube in an anatomical structure by sealing the edges of an epithelial fold.


go_id: GO:0060607
term: cell-cell adhesion involved in sealing an epithelial fold
ontology: BP
definition:
The attachment of one cell to another cell along the edges of two epithelial folds, giving rise to the lumen of an epithelial tube.


go_id: GO:0060608
term: cell-cell adhesion involved in neural tube closure
ontology: BP
definition:
The attachment of one cell to another cell along the edges of two epithelial folds, giving rise to the lumen of the neural tube.


go_id: GO:0060609
term: apoptotic process involved in tube lumen cavitation
ontology: BP
definition:
Any apoptotic process that contributes to the hollowing out of an epithelial rod or cord to form the central hole in a tube.


go_id: GO:0060610
term: mesenchymal cell differentiation involved in mammary gland development
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a mammary gland mesenchymal cell. Mammary gland mesenchymal cells form a loosely connected network of cells that surround the mammary ducts.


go_id: GO:0060611
term: mammary gland fat development
ontology: BP
definition:
The progression of the mammary gland fat over time, from its formation to the mature structure. The mammary fat is an adipose structure in the gland that is invaded by the mammary ducts.


go_id: GO:0060612
term: adipose tissue development
ontology: BP
definition:
The process whose specific outcome is the progression of adipose tissue over time, from its formation to the mature structure. Adipose tissue is specialized tissue that is used to store fat.


go_id: GO:0060613
term: fat pad development
ontology: BP
definition:
The progression of a fat pad from its initial formation to its mature structure. A fat pad is an accumulation of adipose tissue.


go_id: GO:0060614
term: negative regulation of mammary gland development in males by androgen receptor signaling pathway
ontology: BP
definition:
Any process that decreases the rate or extent of mammary gland development in the male by an androgen binding to its receptor, causing a change in state or activity of a cell.


go_id: GO:0060615
term: mammary gland bud formation
ontology: BP
definition:
The morphogenetic process in which a bud forms from the mammary placode. A mammary bud is bulb of epithelial cells that is distinct from the surrounding epidermis.


go_id: GO:0060616
term: mammary gland cord formation
ontology: BP
definition:
The process in which the mammary gland cord forms by elongation of the mammary bud. The cord is formed once the elongating bud breaks through the mesenchyme and reaches the fat pad.


go_id: GO:0060617
term: positive regulation of mammary placode formation by mesenchymal-epithelial signaling
ontology: BP
definition:
Any process that initiates the formation of a mammary placode through a mechanism that mediates the transfer of information from a mesenchymal cell to an epithelial cell resulting in the epithelial cell adopting the identity of a cell of the mammary placode.


go_id: GO:0060618
term: nipple development
ontology: BP
definition:
The progression of the nipple over time, from its formation to the mature structure. The nipple is a part of the mammary gland that protrudes from the surface ectoderm.


go_id: GO:0060619
term: cell migration involved in mammary placode formation
ontology: BP
definition:
The orderly movement of epithelial cells within the mammary line that contributes to the formation of the mammary placode.


go_id: GO:0060620
term: regulation of cholesterol import
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of cholesterol import. Cholesterol import is the directed movement of cholesterol into a cell or organelle.


go_id: GO:0060621
term: negative regulation of cholesterol import
ontology: BP
definition:
Any process that decreases the rate, frequency or extent of cholesterol import. Cholesterol import is the directed movement of cholesterol into a cell or organelle.


go_id: GO:0060622
term: regulation of ascospore wall beta-glucan biosynthetic process
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of ascospore wall beta-glucan biosynthetic process, the chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores.


go_id: GO:0060623
term: regulation of chromosome condensation
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of chromosome condensation, the progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells.


go_id: GO:0060624
term: regulation of ascospore wall (1->3)-beta-D-glucan biosynthetic process
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of ascospore wall (1->3)-beta-D-glucan biosynthetic process, the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D--glucosidic bonds, found in the walls of ascospores.


go_id: GO:0060625
term: regulation of protein deneddylation
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of protein deneddylation, the removal of a ubiquitin-like protein of the NEDD8 type from a protein.


go_id: GO:0060627
term: regulation of vesicle-mediated transport
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell.


go_id: GO:0060628
term: regulation of ER to Golgi vesicle-mediated transport
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of ER to Golgi vesicle-mediated transport, the directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.


go_id: GO:0060629
term: regulation of homologous chromosome segregation
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of homologous chromosome segregation, the cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome sets.


go_id: GO:0060631
term: regulation of meiosis I
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells.


go_id: GO:0060632
term: regulation of microtubule-based movement
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of microtubule-based movement, the movement of organelles, other microtubules and other particles along microtubules, mediated by motor proteins.


go_id: GO:0060633
term: negative regulation of transcription initiation by RNA polymerase II
ontology: BP
definition:
Any process that decreases the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter.


go_id: GO:0060634
term: regulation of 4,6-pyruvylated galactose residue biosynthetic process
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of 4,6-pyruvylated galactose residue biosynthetic process, the chemical reactions and pathways resulting in the formation of the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-(1->3)-. The galactose residue is part of a larger polysaccharide chain.


go_id: GO:0060635
term: positive regulation of (1->3)-beta-D-glucan biosynthetic process
ontology: BP
definition:
Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans.


go_id: GO:0060636
term: negative regulation of (1->3)-beta-D-glucan biosynthetic process
ontology: BP
definition:
Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans.


go_id: GO:0060637
term: positive regulation of lactation by mesenchymal-epithelial cell signaling
ontology: BP
definition:
The process that increases the rate, frequency, or extent of lactation as a result of the secretion of a signal from the mammary fat and its reception by a mammary epithelial cell.


go_id: GO:0060638
term: mesenchymal-epithelial cell signaling
ontology: BP
definition:
Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell where it is received and interpreted.


go_id: GO:0060639
term: positive regulation of salivary gland formation by mesenchymal-epithelial signaling
ontology: BP
definition:
Any process that induces the formation of the salivary gland field by means of the secretion of a signal by a mesenchymal cell and its reception and interpretation by an epithelial cell resulting in it adopting the identity of a salivary gland bud cell.


go_id: GO:0060640
term: positive regulation of dentin-containing tooth bud formation by mesenchymal-epithelial signaling
ontology: BP
definition:
Any process that initiates the formation of a tooth bud by the secretion of a signal from a mesenchymal cell and its reception and subsequent change in the identity of an epithelial cell of the tooth bud.


go_id: GO:0060642
term: white fat cell differentiation involved in mammary gland fat development
ontology: BP
definition:
The process in which a preadipocyte acquires specialized features of a white adipocyte of the mammary gland. White adipocytes have cytoplasmic lipids arranged in a unique vacuole.


go_id: GO:0060644
term: mammary gland epithelial cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland.


go_id: GO:0060645
term: peripheral mammary gland bud epithelial cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized epithelial cell of the mammary placode becomes an epithelial cell at the periphery of the mammary gland bud. Cells at the periphery of the bud are larger that those of the surrounding epithelium and are arranged concentrically.


go_id: GO:0060646
term: internal mammary gland bud epithelial cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized epithelial cell of the mammary placode becomes an internal epithelial cell of the mammary gland bud. Internal cells are small and of irregular shape.


go_id: GO:0060647
term: mesenchymal cell condensation involved in mammary fat development
ontology: BP
definition:
The cell adhesion process in which mammary mesenchyme cells adhere to one another in the initial stages of the formation of mammary fat development.


go_id: GO:0060648
term: mammary gland bud morphogenesis
ontology: BP
definition:
The process in which anatomical structures of the mammary gland buds are generated and organized. Mammary gland buds form by an outpocketing of the mammary placodes and grow to invade the mammary fat, when they form the mammary cord.


go_id: GO:0060650
term: epithelial cell proliferation involved in mammary gland bud elongation
ontology: BP
definition:
The multiplication or reproduction of mammary gland bud epithelial cells, resulting in the elongation of the bud.


go_id: GO:0060651
term: regulation of epithelial cell proliferation involved in mammary gland bud elongation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of mammary gland bud epithelial cell proliferation that results in the elongation of the bud.


go_id: GO:0060652
term: mammary gland cord morphogenesis
ontology: BP
definition:
The process in which anatomical structures of the mammary gland cord are generated and organized. Mammary gland cords form when the mammary gland bud invades the mammary fat.


go_id: GO:0060653
term: epithelial cell differentiation involved in mammary gland cord morphogenesis
ontology: BP
definition:
The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland cord. Epithelial cells of the mammary cord give it its funnel-like shape and some are cornified.


go_id: GO:0060655
term: branching involved in mammary gland cord morphogenesis
ontology: BP
definition:
The process in which the branching structure of the mammary gland cord is generated and organized. The mammary gland cord is a solid epithelial structure that will hollow out, forming the mammary duct.


go_id: GO:0060656
ontology: BP
term:
regulation of branching involved in mammary cord morphogenesis by fat precursor cell-epithelial cell signaling

definition:
Any process that modulates the rate, frequency, or extent of branching of the mammary gland cord as a result of a signal being created by a mammary fat precursor cell and its subsequent reception and interpretation by a mammary cord epithelial cell.


go_id: GO:0060657
term: regulation of mammary gland cord elongation by mammary fat precursor cell-epithelial cell signaling
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of mammary gland cord elongation as a result of a signal being created by a mesenchymal cell that is a precursor to the mammary fat and its subsequent reception and interpretation by an mammary cord epithelial cell.


go_id: GO:0060659
term: nipple sheath formation
ontology: BP
definition:
The developmental process pertaining to the initial formation of the nipple sheath from the unspecified epidermis. This process begins with a circular ingrowth of the epidermis around the region of the mammary sprout. It ends before the region begins to elevate.


go_id: GO:0060660
term: epidermis morphogenesis involved in nipple formation
ontology: BP
definition:
The process in which the epidermis of the nipple sheath is uplifted to form an umbrella-like projection.


go_id: GO:0060661
term: submandibular salivary gland formation
ontology: BP
definition:
The developmental process pertaining to the initial formation of a submandibular salivary gland. This process begins with a thickening of the epithelium next to the tongue and ends when a bud linked to the oral surface is formed.


go_id: GO:0060662
term: salivary gland cavitation
ontology: BP
definition:
The process in which the solid core of salivary epithelium gives rise to the hollow tube of the gland.


go_id: GO:0060664
term: epithelial cell proliferation involved in salivary gland morphogenesis
ontology: BP
definition:
The multiplication or reproduction of epithelial cells of the submandibular salivary gland, resulting in the expansion of a cell population and the shaping of the gland.


go_id: GO:0060665
ontology: BP
term:
regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling

definition:
Any process that modulates the rate, frequency, or extent of branching involved in salivary gland morphogenesis as a result of signals being generated by the mesenchyme and received and interpreted by the salivary gland epithelium.


go_id: GO:0060667
term: branch elongation involved in salivary gland morphogenesis
ontology: BP
definition:
The differential growth of the salivary branches along their axis, resulting in the growth of a branch.


go_id: GO:0060668
ontology: BP
term:
regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling

definition:
Any process that modulates the rate, frequency, or extent of salivary gland branching as a result of the transfer of information from the extracellular matrix to the epithelium of the salivary gland.


go_id: GO:0060670
term: branching involved in labyrinthine layer morphogenesis
ontology: BP
definition:
The process in which the branches of the fetal placental villi are generated and organized. The villous part of the placenta is called the labyrinth layer.


go_id: GO:0060671
term: epithelial cell differentiation involved in embryonic placenta development
ontology: BP
definition:
The process in which a trophoblast cell acquires specialized features of an epithelial cell of the placental labyrinthine layer.


go_id: GO:0060672
term: epithelial cell morphogenesis involved in placental branching
ontology: BP
definition:
The change in form (cell shape and size) that occurs when a trophoblast cell elongates to contribute to the branching of the placenta.


go_id: GO:0060674
term: placenta blood vessel development
ontology: BP
definition:
The process whose specific outcome is the progression of a blood vessel of the placenta over time, from its formation to the mature structure.


go_id: GO:0060676
term: ureteric bud formation
ontology: BP
definition:
The developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct. This process begins when the bud protrudes from the duct and ends when it is a recognizable bud.


go_id: GO:0060677
term: ureteric bud elongation
ontology: BP
definition:
The developmental growth in which the ureteric bud grows along its axis beginning with the growth of the primary ureteric bud and ending when the branches of the bud have elongated.


go_id: GO:0060682
term: primary ureteric bud growth
ontology: BP
definition:
The process in which the primary ureteric bud grows along its axis dorsally toward the metanephric blastema.


go_id: GO:0060683
ontology: BP
term:
regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling

definition:
Any process that modulates the rate, frequency, or extent of salivary gland branching as a result of the transfer of information from the epithelial cells to the mesenchymal cells of the salivary gland.


go_id: GO:0060684
term: epithelial-mesenchymal cell signaling
ontology: BP
definition:
Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell where it is interpreted.


go_id: GO:0060685
term: regulation of prostatic bud formation
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of prostatic bud formation, the morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth.


go_id: GO:0060686
term: negative regulation of prostatic bud formation
ontology: BP
definition:
Any process that decreases the rate, frequency, or extent of prostatic bud formation, the morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth.


go_id: GO:0060687
term: regulation of branching involved in prostate gland morphogenesis
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of prostate gland branching, the process in which the branching structure of the prostate gland is generated and organized. A branch is a division or offshoot from a main stem.


go_id: GO:0060688
term: regulation of morphogenesis of a branching structure
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of branching morphogenesis, the process in which the anatomical structures of branches are generated and organized.


go_id: GO:0060689
term: cell differentiation involved in salivary gland development
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize the cells of the salivary gland.


go_id: GO:0060690
term: epithelial cell differentiation involved in salivary gland development
ontology: BP
definition:
The process in which a relatively unspecialized cell acquire specialized structural and/or functional features of an epithelial cell of the salivary gland.


go_id: GO:0060691
term: epithelial cell maturation involved in salivary gland development
ontology: BP
definition:
The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell of the salivary gland to attain its fully functional state.


go_id: GO:0060692
term: mesenchymal cell differentiation involved in salivary gland development
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the salivary gland. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types.


go_id: GO:0060693
term: regulation of branching involved in salivary gland morphogenesis
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of branching morphogenesis in the salivary gland epithelium.


go_id: GO:0060696
term: regulation of phospholipid catabolic process
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of phospholipid catabolism, the chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester.


go_id: GO:0060697
term: positive regulation of phospholipid catabolic process
ontology: BP
definition:
Any process that increases the rate, frequency, or extent of phospholipid catabolism, the chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester.


go_id: GO:0060699
term: regulation of endoribonuclease activity
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of the catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.


go_id: GO:0060700
term: regulation of ribonuclease activity
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of ribonuclease activity, catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.


go_id: GO:0060701
term: negative regulation of ribonuclease activity
ontology: BP
definition:
Any process that decreases the rate, frequency, or extent of ribonuclease activity, catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.


go_id: GO:0060702
term: negative regulation of endoribonuclease activity
ontology: BP
definition:
Any process that decreases the rate, frequency or extent of the catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.


go_id: GO:0060704
term: acinar cell differentiation involved in salivary gland development
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize an acinar cell of the salivary gland. Acinar cells are protein-secreting cells in the gland.


go_id: GO:0060705
term: neuron differentiation involved in salivary gland development
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize the neurons of the salivary gland.


go_id: GO:0060706
term: cell differentiation involved in embryonic placenta development
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of the embryonic placenta.


go_id: GO:0060707
term: trophoblast giant cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a trophoblast giant cell of the placenta. Trophoblast giant cells are the cell of the placenta that line the maternal decidua.


go_id: GO:0060708
term: spongiotrophoblast differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell of the ectoplacental cone acquires specialized features of a spongiotrophoblast of the placenta. A spongiotrophoblast cell is a basophilic cell.


go_id: GO:0060709
term: glycogen cell differentiation involved in embryonic placenta development
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a glycogen cell of the placenta. A glycogen cell is a vacuolated glycogen-rich cell that appears in compact cell islets of the spongiotrophoblast layer.


go_id: GO:0060710
term: chorio-allantoic fusion
ontology: BP
definition:
The cell-cell adhesion process in which the cells of the chorion fuse to the cells of the allantois.


go_id: GO:0060711
term: labyrinthine layer development
ontology: BP
definition:
The process in which the labyrinthine layer of the placenta progresses, from its formation to its mature state.


go_id: GO:0060712
term: spongiotrophoblast layer development
ontology: BP
definition:
The process in which the spongiotrophoblast layer of the placenta progresses from its formation to its mature state.


go_id: GO:0060714
term: labyrinthine layer formation
ontology: BP
definition:
The developmental process pertaining to the initial formation of the labyrinthine layer of the placenta.


go_id: GO:0060715
term: syncytiotrophoblast cell differentiation involved in labyrinthine layer development
ontology: BP
definition:
The process in which a chorionic trophoblast cell acquires specialized features of a syncytiotrophoblast of the labyrinthine layer of the placenta.


go_id: GO:0060716
term: labyrinthine layer blood vessel development
ontology: BP
definition:
The process whose specific outcome is the progression of a blood vessel of the labyrinthine layer of the placenta over time, from its formation to the mature structure. The embryonic vessels grow through the layer to come in close contact with the maternal blood supply.


go_id: GO:0060717
term: chorion development
ontology: BP
definition:
The biological process whose specific outcome is the progression of a chorion from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The chorion is an extraembryonic membrane.


go_id: GO:0060718
term: chorionic trophoblast cell differentiation
ontology: BP
definition:
The process in which relatively unspecialized cells of the ectoplacental cone acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer.


go_id: GO:0060719
term: chorionic trophoblast cell development
ontology: BP
definition:
The process whose specific outcome is the progression of the chorionic trophoblast over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.


go_id: GO:0060720
term: spongiotrophoblast cell proliferation
ontology: BP
definition:
The multiplication or reproduction of spongiotrophoblast cells, resulting in the expansion of the population in the spongiotrophoblast layer.


go_id: GO:0060722
term: cell proliferation involved in embryonic placenta development
ontology: BP
definition:
The multiplication or reproduction of cells, resulting in the expansion of the population in the embryonic placenta.


go_id: GO:0060723
term: regulation of cell proliferation involved in embryonic placenta development
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of cell proliferation involved in embryonic placenta development.


go_id: GO:0060724
term: coreceptor activity involved in epidermal growth factor receptor signaling pathway
ontology: MF
definition:
Combining with an extracellular messenger, and in cooperation with a primary EGF receptor, initiating a change in cell activity through the EGF receptor signaling pathway.


go_id: GO:0060725
term: regulation of coreceptor activity
ontology: BP
definition:
Any process that modulates the rate or frequency of coreceptor activity, combining with an extracellular or intracellular messenger, and in cooperation with a nearby primary receptor, initiating a change in cell activity.


go_id: GO:0060726
term: regulation of coreceptor activity involved in epidermal growth factor receptor signaling pathway
ontology: BP
definition:
Any process that modulates the rate or frequency of coreceptor activity involved in epidermal growth factor receptor signaling pathway.


go_id: GO:0060727
ontology: BP
term:
positive regulation of coreceptor activity involved in epidermal growth factor receptor signaling pathway

definition:
Any process that increases the rate or frequency of coreceptor activity involved in epidermal growth factor receptor signaling pathway.


go_id: GO:0060728
ontology: BP
term:
negative regulation of coreceptor activity involved in epidermal growth factor receptor signaling pathway

definition:
Any process that decreases the rate or frequency of coreceptor activity involved in epidermal growth factor receptor signaling pathway.


go_id: GO:0060729
term: intestinal epithelial structure maintenance
ontology: BP
definition:
A tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium.


go_id: GO:0060730
term: regulation of intestinal epithelial structure maintenance
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of intestinal epithelial structure maintenance, a tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium.


go_id: GO:0060731
term: positive regulation of intestinal epithelial structure maintenance
ontology: BP
definition:
Any process the increases the rate, frequency or extent of intestinal epithelial structure maintenance, a tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium.


go_id: GO:0060732
term: positive regulation of inositol phosphate biosynthetic process
ontology: BP
definition:
Any process that increases the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.


go_id: GO:0060734
term: regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a cellular response to endoplasmic reticulum stress.


go_id: GO:0060735
term: regulation of eIF2 alpha phosphorylation by dsRNA
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a cellular response to double-stranded RNA.


go_id: GO:0060736
term: prostate gland growth
ontology: BP
definition:
The increase in size or mass of the prostate gland where the increase in size or mass has the specific outcome of the progression of the gland, from its formation to its mature state.


go_id: GO:0060737
term: prostate gland morphogenetic growth
ontology: BP
definition:
The differential increase in size or mass of the prostate gland that contributes to the gland attaining its form.


go_id: GO:0060738
term: epithelial-mesenchymal signaling involved in prostate gland development
ontology: BP
definition:
Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell where it is interpreted and contributes to the progression of the prostate gland over time.


go_id: GO:0060739
term: mesenchymal-epithelial cell signaling involved in prostate gland development
ontology: BP
definition:
Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell where it is received and interpreted contributing to the progression of the prostate gland over time.


go_id: GO:0060740
term: prostate gland epithelium morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of epithelia of the prostate gland are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube.


go_id: GO:0060741
term: prostate gland stromal morphogenesis
ontology: BP
definition:
The process in which the prostate gland stroma is generated and organized. The prostate gland stroma is made up of the mesenchymal or fibroblast cells of the prostate gland.


go_id: GO:0060742
term: epithelial cell differentiation involved in prostate gland development
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell of the prostate gland.


go_id: GO:0060743
term: epithelial cell maturation involved in prostate gland development
ontology: BP
definition:
The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell of the prostate gland to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface.


go_id: GO:0060744
term: mammary gland branching involved in thelarche
ontology: BP
definition:
The process in which the branching structure of the mammary gland duct is generated and organized during the period of sexual maturity in mammals. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.


go_id: GO:0060745
term: mammary gland branching involved in pregnancy
ontology: BP
definition:
The process in which the branching structure of the mammary gland duct is generated and organized as a part of pregnancy.


go_id: GO:0060748
term: tertiary branching involved in mammary gland duct morphogenesis
ontology: BP
definition:
The branching process in which the mammary gland ducts form tertiary branches off of the secondary branches as part of diestrus and pregnancy.


go_id: GO:0060749
term: mammary gland alveolus development
ontology: BP
definition:
The progression of the mammary gland alveolus over time, from its formation to its mature state. The mammary gland alveolus is a sac-like structure that is found in the mature gland.


go_id: GO:0060750
term: epithelial cell proliferation involved in mammary gland duct elongation
ontology: BP
definition:
The multiplication or reproduction of mammary gland branch epithelial cells, resulting in the elongation of the branch. The mammary gland branch differs from the bud in that it is not the initial curved portion of the outgrowth.


go_id: GO:0060753
term: regulation of mast cell chemotaxis
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus.


go_id: GO:0060754
term: positive regulation of mast cell chemotaxis
ontology: BP
definition:
Any process that increases the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus.


go_id: GO:0060755
term: negative regulation of mast cell chemotaxis
ontology: BP
definition:
Any process that decreases the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus.


go_id: GO:0060758
term: foraging behavior by probing substrate
ontology: BP
definition:
Foraging behavior in which an anatomical part of the organism is inserted into the substrate to locate food.


go_id: GO:0060762
term: regulation of branching involved in mammary gland duct morphogenesis
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of branching involved in mammary gland duct morphogenesis.


go_id: GO:0060763
term: mammary duct terminal end bud growth
ontology: BP
definition:
The morphogenetic growth of the large, club-shaped terminal end of a mammary gland duct during prepubertal growth and during puberty.


go_id: GO:0060764
term: cell-cell signaling involved in mammary gland development
ontology: BP
definition:
Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mammary gland, from its initial state to the mature structure.


go_id: GO:0060765
term: regulation of androgen receptor signaling pathway
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of the androgen receptor signaling pathway.


go_id: GO:0060766
term: negative regulation of androgen receptor signaling pathway
ontology: BP
definition:
Any process that decreases the rate, frequency, or extent of the androgen receptor signaling pathway.


go_id: GO:0060767
term: epithelial cell proliferation involved in prostate gland development
ontology: BP
definition:
The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the progression of the prostate gland over time.


go_id: GO:0060768
term: regulation of epithelial cell proliferation involved in prostate gland development
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time.


go_id: GO:0060769
term: positive regulation of epithelial cell proliferation involved in prostate gland development
ontology: BP
definition:
Any process that increases the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time.


go_id: GO:0060770
term: negative regulation of epithelial cell proliferation involved in prostate gland development
ontology: BP
definition:
Any process that decreases the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time.


go_id: GO:0060771
term: phyllotactic patterning
ontology: BP
definition:
The radial pattern formation process that results in the formation of plant organs (leaves or leaf-like structures) or flower primordia around a central axis.


go_id: GO:0060772
term: leaf phyllotactic patterning
ontology: BP
definition:
The radial pattern formation process that results in the formation of leaf primordia around the center of a shoot apical meristem.


go_id: GO:0060773
term: flower phyllotactic patterning
ontology: BP
definition:
The radial pattern formation process that results in the formation of floral organ primordia around a central axis in a flower primordium.


go_id: GO:0060774
term: auxin mediated signaling pathway involved in phyllotactic patterning
ontology: BP
definition:
The series of molecular signals generated in response to detection of auxin that contributes to the radial pattern formation process resulting in the formation of leaf or flower primordia around the center of a shoot apical meristem.


go_id: GO:0060775
term: planar cell polarity pathway involved in gastrula mediolateral intercalation
ontology: BP
definition:
The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) contributing to the interdigitation of cells along the mediolateral axis during gastrulation.


go_id: GO:0060776
term: simple leaf morphogenesis
ontology: BP
definition:
The leaf morphogenesis process which results in the shaping of a simple leaf. A simple leaf is a leaf in which the lamina is undivided.


go_id: GO:0060777
term: compound leaf morphogenesis
ontology: BP
definition:
The leaf morphogenesis process that results in the shaping of a compound leaf. A compound leaf is a leaf having two or more distinct leaflets that are evident as such from early in development.


go_id: GO:0060778
term: primary leaflet morphogenesis
ontology: BP
definition:
The process in which the primary leaflet attains its shape. A primary leaflet is a leaflet that develops directly from the rachis.


go_id: GO:0060779
term: secondary leaflet morphogenesis
ontology: BP
definition:
The process in which the secondary leaflet attains its shape. A secondary leaflet develops by branching or division of a primary leaflet.


go_id: GO:0060780
term: intercalary leaflet morphogenesis
ontology: BP
definition:
The process in which the intercalary leaflet attains its shape. An intercalary leaflet is a leaflet that develops between primary leaflets.


go_id: GO:0060781
term: mesenchymal cell proliferation involved in prostate gland development
ontology: BP
definition:
The multiplication or reproduction of mesenchymal cells, resulting in the expansion of a cell population that contributes to the progression of the prostate gland over time.


go_id: GO:0060782
term: regulation of mesenchymal cell proliferation involved in prostate gland development
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the prostate gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.


go_id: GO:0060783
term: mesenchymal smoothened signaling pathway involved in prostate gland development
ontology: BP
definition:
The series of molecular signals generated as a consequence of activation of the transmembrane Smoothened-type protein in the mesenchymal cells of the prostate that contribute to the progression of the prostate over time. This process contributes to lung development.


go_id: GO:0060784
term: regulation of cell proliferation involved in tissue homeostasis
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of cell proliferation resulting in the maintenance of a steady-state number of cells within a tissue.


go_id: GO:0060785
term: regulation of apoptosis involved in tissue homeostasis
ontology: BP
definition:
Any process that modulates the occurrence or rate of cell death by apoptosis that results in the maintenance of the steady-state number of cells within a tissue.


go_id: GO:0060786
term: regulation of cell differentiation involved in tissue homeostasis
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of cell differentiation that contributes to the maintenance of a steady state of a cell type within a tissue.


go_id: GO:0060787
ontology: BP
term:
positive regulation of posterior neural plate formation by fibroblast growth factor receptor signaling pathway

definition:
Any process that increases the rate or extent of the formation of the posterior neural plate, the posterior end of the flat, thickened layer of ectodermal cells known as the neural plate.


go_id: GO:0060788
term: ectodermal placode formation
ontology: BP
definition:
The developmental process in which an ectodermal placode forms. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm.


go_id: GO:0060789
term: hair follicle placode formation
ontology: BP
definition:
The developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud.


go_id: GO:0060790
term: tooth placode formation
ontology: BP
definition:
The developmental process in which the tooth placode forms. A tooth placode is a thickening of the ectoderm that will give rise to the tooth bud.


go_id: GO:0060791
term: sebaceous gland placode formation
ontology: BP
definition:
The developmental process in which a sebaceous gland placode forms. A sebaceous gland placode is a thickening of the ectoderm that will give rise to the sebaceous gland bud.


go_id: GO:0060792
term: sweat gland development
ontology: BP
definition:
The progression of the sweat gland over time, from its formation to the mature structure. Sweat glands secrete an aqueous solution that is used in thermoregulation.


go_id: GO:0060793
term: sweat gland placode formation
ontology: BP
definition:
The developmental process in which the sweat gland placode forms. An sweat gland placode is a thickening of the ectoderm that will give rise to the sweat gland bud.


go_id: GO:0060795
term: cell fate commitment involved in formation of primary germ layer
ontology: BP
definition:
The commitment of cells to specific cell fates of the endoderm, ectoderm, or mesoderm as a part of gastrulation.


go_id: GO:0060797
ontology: BP
term:
transforming growth factor beta receptor signaling pathway involved in primary germ layer cell fate commitment

definition:
The series of molecular signals initiated by an extracellular ligand binding to a transforming growth factor beta receptor on the surface of a target cell, which contributes to an unspecified cell adopting a mesoderm fate.


go_id: GO:0060798
ontology: BP
term:
transforming growth factor beta receptor signaling pathway involved in mesodermal cell fate specification

definition:
The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands and ultimately resulting in the specification of a mesodermal fate.


go_id: GO:0060799
ontology: BP
term:
transforming growth factor beta receptor signaling pathway involved in endodermal cell fate specification

definition:
The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands and ultimately resulting in the commitment of an unspecified fate to adopt an endoderm fate.


go_id: GO:0060800
term: regulation of cell differentiation involved in embryonic placenta development
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state.


go_id: GO:0060801
ontology: BP
term:
negative regulation of trophoblast cell differentiation by transforming growth factor beta signaling pathway

definition:
The transforming growth factor signaling process that decreases the rate, frequency, or extent of trophoblast stem cells differentiating into the more mature cells of the trophoblast.


go_id: GO:0060802
ontology: BP
term:
epiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification

definition:
Any process that mediates the transfer of information from an epiblast cell to an extraembryonic ectoderm cell that contributes to the specification of the anterior/posterior axis.


go_id: GO:0060803
term: BMP signaling pathway involved in mesodermal cell fate specification
ontology: BP
definition:
The series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to its receptor on the surface of a target cell, which contributes to a cell becoming specified to adopt a mesodermal fate.


go_id: GO:0060804
term: positive regulation of Wnt signaling pathway by BMP signaling pathway
ontology: BP
definition:
The series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that results in an increase in the rate, frequency or extent of a Wnt signaling pathway.


go_id: GO:0060805
ontology: BP
term:
negative regulation of trophoblast cell differentiation by transcription regulation from RNA polymerase II promoter

definition:
Any process that modulates the rate, frequency or extent of transcription from an RNA polymerase II promoter ultimately resulting in a decrease in trophoblast stem cells differentiating into the more mature cells of the trophoblast.


go_id: GO:0060806
term: negative regulation of cell differentiation involved in embryonic placenta development
ontology: BP
definition:
Any process that decreases the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state.


go_id: GO:0060808
term: positive regulation of mesodermal to mesenchymal transition involved in gastrulation
ontology: BP
definition:
Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where a mesodermal cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell as part of the process of gastrulation.


go_id: GO:0060809
term: mesodermal to mesenchymal transition involved in gastrulation
ontology: BP
definition:
The epithelial to mesenchymal transition process in which a mesodermal cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell as part of the process of gastrulation.


go_id: GO:0060810
term: intracellular mRNA localization involved in pattern specification process
ontology: BP
definition:
Any process in which mRNA is transported to, or maintained in, a specific location within an oocyte that results in a pattern being established in the embryo.


go_id: GO:0060811
term: intracellular mRNA localization involved in anterior/posterior axis specification
ontology: BP
definition:
Any process in which mRNA is transported to, or maintained in, a specific location within the oocyte and/or syncytial embryo that contributes to the specification of the anterior/posterior axis.


go_id: GO:0060812
term: orthodenticle mRNA localization
ontology: BP
definition:
Any process in which orthodenticle mRNA is transported to and maintained in the oocyte and/or syncytial embryo as part of the process that will specify the anterior/posterior axis.


go_id: GO:0060813
term: anterior mRNA localization involved in anterior/posterior axis specification
ontology: BP
definition:
Any process in which a mRNA is transported to, and maintained in the anterior portion of the oocyte and/or syncytial embryo contributing to the specification of the anterior/posterior axis.


go_id: GO:0060814
term: posterior mRNA localization involved in anterior/posterior axis specification
ontology: BP
definition:
Any process in which a mRNA is transported to and maintained in the oocyte and/or syncytial embryo contributing to the specification of the anterior/posterior axis.


go_id: GO:0060815
term: regulation of translation involved in anterior/posterior axis specification
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of translation of mRNAs that contribute to the specification of the anterior/posterior axis.


go_id: GO:0060816
term: random inactivation of X chromosome
ontology: BP
definition:
Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on either the paternal or maternal X-chromosome in the XX sex.


go_id: GO:0060817
term: inactivation of paternal X chromosome
ontology: BP
definition:
Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes specifically on the paternal X-chromosome in the XX sex.


go_id: GO:0060818
term: inactivation of paternal X chromosome by genomic imprinting
ontology: BP
definition:
Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on the paternal X-chromosome in the XX sex by genomic imprinting.


go_id: GO:0060819
term: inactivation of X chromosome by genomic imprinting
ontology: BP
definition:
Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex by genomic imprinting.


go_id: GO:0060820
term: inactivation of X chromosome by heterochromatin formation
ontology: BP
definition:
Compensating for the two-fold variation in X-chromosome: autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex by the mechanism of heterochromatin formation.


go_id: GO:0060822
ontology: BP
term:
transforming growth factor beta receptor signaling pathway involved in axial mesodermal cell fate specification

definition:
The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands and ultimately resulting in the specification of an axial mesodermal fate.


go_id: GO:0060823
term: canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation
ontology: BP
definition:
The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the formation of the neural plate anterior/posterior pattern.


go_id: GO:0060824
ontology: BP
term:
retinoic acid receptor signaling pathway involved in neural plate anterior/posterior pattern formation

definition:
The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that contributes to the formation of the anterior/posterior pattern of the neural plate.


go_id: GO:0060825
ontology: BP
term:
fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation

definition:
The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands contributing to the anterior/posterior pattern of the neural plate.


go_id: GO:0060826
ontology: BP
term:
transforming growth factor beta receptor signaling pathway involved in neural plate anterior/posterior pattern formation

definition:
The series of molecular signals initiated by an extracellular ligand binding to a transforming growth factor beta receptor on the surface of a target cell, which contributes to the formation of the neural plate anterior/posterior pattern.


go_id: GO:0060827
ontology: BP
term:
regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation

definition:
Any process that modulates the rate, frequency, or extent of Wnt signaling through beta-catenin that results in the formation of the neural plate anterior/posterior pattern.


go_id: GO:0060828
term: regulation of canonical Wnt signaling pathway
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.


go_id: GO:0060829
ontology: BP
term:
negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation

definition:
Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin in the anterior end of the neural plate. This regulation sets up a Wnt signaling gradient along the anterior/posterior axis.


go_id: GO:0060830
term: ciliary receptor clustering involved in smoothened signaling pathway
ontology: BP
definition:
Grouping of smoothened or patched receptors in a cilium, contributing to the smoothened signaling pathway.


go_id: GO:0060831
term: smoothened signaling pathway involved in dorsal/ventral neural tube patterning
ontology: BP
definition:
The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened contributing to the dorsal/ventral pattern of the neural tube.


go_id: GO:0060832
term: oocyte animal/vegetal axis specification
ontology: BP
definition:
The establishment, maintenance and elaboration of the animal/vegetal axis in the oocyte. The animal/vegetal axis of an oocyte is defined by the placement of the nucleus in the oocyte and can sometimes be identified by the asymmetric placement of other substances such as yolk in the oocyte. The pole of the egg that is closest to the nucleus defines the animal end, with the axis passing through the nucleus.


go_id: GO:0060833
term: Wnt signaling pathway involved in animal/vegetal axis specification
ontology: BP
definition:
The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell contributing to the specification of the animal/vegetal axis of an oocyte.


go_id: GO:0060834
term: oral/aboral axis specification
ontology: BP
definition:
The establishment, maintenance and elaboration of a line that delineates the mouth and the anus of an embryo.


go_id: GO:0060835
ontology: BP
term:
transforming growth factor receptor beta signaling pathway involved in oral/aboral axis specification

definition:
The series of molecular signals initiated by an extracellular ligand binding to a transforming growth factor beta receptor on the surface of a target cell, which contributes to the specification of the oral/aboral axis.


go_id: GO:0060836
term: lymphatic endothelial cell differentiation
ontology: BP
definition:
The process in which a venous blood vessel endothelial cell acquires specialized features of a lymphatic vessel endothelial cell, a thin flattened cell that lines the inside surfaces of lymph vessels.


go_id: GO:0060837
term: blood vessel endothelial cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell, a thin flattened cell that lines the inside surfaces of blood vessels.


go_id: GO:0060838
term: lymphatic endothelial cell fate commitment
ontology: BP
definition:
The commitment of a venous blood vessel endothelial cell to a lymphatic endothelial cell fate and its capacity to differentiate into a lymphatic endothelial cell.


go_id: GO:0060839
term: endothelial cell fate commitment
ontology: BP
definition:
The commitment of a cell to an endothelial cell fate and its capacity to differentiate into an endothelial cell.


go_id: GO:0060840
term: artery development
ontology: BP
definition:
The progression of the artery over time, from its initial formation to the mature structure. An artery is a blood vessel that carries blood away from the heart to a capillary bed.


go_id: GO:0060841
term: venous blood vessel development
ontology: BP
definition:
The progression of the venous blood vessel over time from its initial formation to the mature structure. Venous blood vessels carry blood back to the heart after the capillary bed.


go_id: GO:0060842
term: arterial endothelial cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized endothelial cell acquires specialized features of an arterial endothelial cell, a thin flattened cell that lines the inside surfaces of arteries.


go_id: GO:0060843
term: venous endothelial cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized endothelial cell acquires specialized features of a venous endothelial cell, a thin flattened cell that lines the inside surfaces of veins.


go_id: GO:0060844
term: arterial endothelial cell fate commitment
ontology: BP
definition:
The commitment of a cell to an arterial endothelial cell fate and its capacity to differentiate into an arterial endothelial cell.


go_id: GO:0060845
term: venous endothelial cell fate commitment
ontology: BP
definition:
The commitment of a cell to a venous endothelial cell fate and its capacity to differentiate into an venous endothelial cell.


go_id: GO:0060846
term: blood vessel endothelial cell fate commitment
ontology: BP
definition:
The commitment of a cell to a blood vessel endothelial cell fate and its capacity to differentiate into a blood vessel endothelial cell.


go_id: GO:0060847
term: endothelial cell fate specification
ontology: BP
definition:
The process involved in the specification of identity of an endothelial cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.


go_id: GO:0060848
term: endothelial cell fate determination
ontology: BP
definition:
A process involved in cell fate commitment of an endothelial cell. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.


go_id: GO:0060851
ontology: BP
term:
vascular endothelial growth factor receptor signaling pathway involved in lymphatic endothelial cell fate commitment

definition:
The series of molecular signals generated as a consequence of vascular endothelial growth factor receptor binding to one of its physiological ligands that contributes to the commitment of a venous endothelial cell to a lymphatic endothelial cell fate.


go_id: GO:0060853
term: Notch signaling pathway involved in arterial endothelial cell fate commitment
ontology: BP
definition:
The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell and contributing to the commitment of a cell to an arterial endothelial cell fate.


go_id: GO:0060854
term: branching involved in lymph vessel morphogenesis
ontology: BP
definition:
The process of the coordinated growth and sprouting of lymph vessels giving rise to the organized lymphatic system.


go_id: GO:0060855
term: venous endothelial cell migration involved in lymph vessel development
ontology: BP
definition:
The orderly movement of venous endothelial cells out of the veins giving rise to the precursors of lymphatic endothelial cells.


go_id: GO:0060856
term: establishment of blood-brain barrier
ontology: BP
definition:
Establishment of the barrier between the blood and the brain. The cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier.


go_id: GO:0060857
term: establishment of glial blood-brain barrier
ontology: BP
definition:
Establishment of the glial barrier between the blood and the brain. The glial cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier.


go_id: GO:0060858
term: vesicle-mediated transport involved in floral organ abscission
ontology: BP
definition:
The directed movement of substances within a cell by a cellular process that begins with the formation of membrane-bounded vesicles in which the transported substances are enclosed or located in the vesicle membrane which are then targeted to, and fuse with, an acceptor membrane contributing to the shedding of a floral organ.


go_id: GO:0060860
term: regulation of floral organ abscission
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of floral organ abscission, the controlled shedding of floral organs.


go_id: GO:0060861
term: positive regulation of floral organ abscission
ontology: BP
definition:
Any process that increases the rate, frequency, or extent of floral organ shedding, the controlled shedding of floral organs.


go_id: GO:0060862
term: negative regulation of floral organ abscission
ontology: BP
definition:
Any process that decreases the rate, frequency, or extent of floral organ abscission, the controlled shedding of floral organs.


go_id: GO:0060863
term: regulation of floral organ abscission by signal transduction
ontology: BP
definition:
The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately modulating the rate, or extent of floral organ abscission.


go_id: GO:0060865
ontology: BP
term:
negative regulation of floral organ abscission by transmembrane receptor protein serine/threonine kinase signaling pathway

definition:
The series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand and contributing to the decrease in the rate or frequency of floral organ abscission.


go_id: GO:0060869
ontology: BP
term:
transmembrane receptor protein serine/threonine kinase signaling pathway involved in floral organ abscission

definition:
The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell where the receptor possesses serine/threonine kinase activity, which contributes to the process of floral organ abscission.


go_id: GO:0060870
term: cell wall disassembly involved in floral organ abscission
ontology: BP
definition:
A cellular process that results in the breakdown of the cell wall that contributes to the process of floral organ abscission.


go_id: GO:0060873
term: anterior semicircular canal development
ontology: BP
definition:
The progession of the anterior semicircular canal from its initial formation to the mature structure.


go_id: GO:0060874
term: posterior semicircular canal development
ontology: BP
definition:
The progession of the posterior semicircular canal from its initial formation to the mature structure.


go_id: GO:0060875
term: lateral semicircular canal development
ontology: BP
definition:
The progession of the lateral semicircular canal from its initial formation to the mature structure.


go_id: GO:0060876
term: semicircular canal formation
ontology: BP
definition:
The developmental process pertaining to the initial formation of the semicircular canal from the otic vesicle. This process begins with the regionalization of the vesicle that specifies the area where the vesicles will form and continues through the process of fusion which forms the initial tubes.


go_id: GO:0060877
term: regionalization involved in semicircular canal formation
ontology: BP
definition:
The pattern specification process that results in the subdivision of the otic epithelium in space to define an area or volume in which cells will differentiate to give rise to the semicircular canals.


go_id: GO:0060878
term: pouch outgrowth involved in semicircular canal formation
ontology: BP
definition:
The morphogenetic process in which an epithelial sheet bends along a linear axis and gives rise to a pouch that will form a semicircular canal.


go_id: GO:0060879
term: semicircular canal fusion
ontology: BP
definition:
Creation of the central hole of the semicircular canal by sealing the edges of the pouch that forms during the process of semicircular canal formation.


go_id: GO:0060880
term: cell morphogenesis involved in semicircular canal fusion
ontology: BP
definition:
The change in form (cell shape and size) that occurs when a semicircular canal epithelial cell acquires the structural features that allow it to contribute to the process of semicircular canal fusion.


go_id: GO:0060882
term: basement membrane disassembly involved in semicircular canal fusion
ontology: BP
definition:
A process that results in the breakdown of the basement membrane that contributes to the process of semicircular canal fusion.


go_id: GO:0060883
ontology: BP
term:
regulation of basement membrane disassembly involved in semicircular canal fusion by cell communication

definition:
Any process that mediates interactions between a cell and its surroundings that modulates of the rate, frequency or extent of basement membrane disassembly involved in semicircular canal fusion.


go_id: GO:0060885
term: clearance of cells from fusion plate by apoptotic process
ontology: BP
definition:
Any apoptotic process that contributes to the shaping of the semicircular canal by removing cells in the fusion plate, forming the loops of the canals.


go_id: GO:0060886
term: clearance of cells from fusion plate by epithelial to mesenchymal transition
ontology: BP
definition:
The process of epithelial to mesenchymal transition that contributes to the shaping of the semicircular canal by effectively removing epithelial cells from the fusion plate, forming the loops of the canals.


go_id: GO:0060887
term: limb epidermis development
ontology: BP
definition:
The process whose specific outcome is the progression of the epidermis of the limb over time, from its formation to the mature structure. The limb epidermis is the outer epithelial layer of the limb, it is a complex stratified squamous epithelium.


go_id: GO:0060888
term: limb epidermis stratification
ontology: BP
definition:
The pattern specification process that results in the subdivision of the epidermis of the limb in space to define a volume in which specific patterns of basal cell, spinous cell and granular cells will differentiate giving rise to the layers of the limb epidermis.


go_id: GO:0060889
term: limb basal epidermal cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal basal cell. A epidermal basal cell cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into more specialized cell of the limb epidermis.


go_id: GO:0060890
term: limb spinous cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal spinous cell.


go_id: GO:0060891
term: limb granular cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal granular cell.


go_id: GO:0060892
term: limb basal epidermal cell fate specification
ontology: BP
definition:
The process in which a cell becomes capable of differentiating autonomously into an limb basal epidermal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.


go_id: GO:0060893
term: limb granular cell fate specification
ontology: BP
definition:
The process in which a cell becomes capable of differentiating autonomously into an limb granular cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.


go_id: GO:0060894
term: limb spinous cell fate specification
ontology: BP
definition:
The process in which a cell becomes capable of differentiating autonomously into a limb spinous cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.


go_id: GO:0060895
term: retinoic acid receptor signaling pathway involved in spinal cord dorsal/ventral patterning
ontology: BP
definition:
The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that contributes to the dorsal ventral patterning of the spinal cord.


go_id: GO:0060896
term: neural plate pattern specification
ontology: BP
definition:
The developmental process that results in the creation of defined areas or spaces within the neural plate to which cells respond and eventually are instructed to differentiate.


go_id: GO:0060897
term: neural plate regionalization
ontology: BP
definition:
The pattern specification process that results in the subdivision of an axis or axes of the neural plate in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment.


go_id: GO:0060898
term: eye field cell fate commitment involved in camera-type eye formation
ontology: BP
definition:
The commitment of neurectodermal cells to cells of the eye field and their capacity to differentiate into eye field cells. Eye field cells are neurectodermal cells that will form the optic placode.


go_id: GO:0060900
term: embryonic camera-type eye formation
ontology: BP
definition:
The developmental process pertaining to the initial formation of a camera-type eye from unspecified neurectoderm. This process begins with the differentiation of cells that form the optic field and ends when the optic cup has attained its shape.


go_id: GO:0060901
term: regulation of hair cycle by canonical Wnt signaling pathway
ontology: BP
definition:
The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that modulates the rate, frequency or extent of the hair cycle.


go_id: GO:0060902
term: regulation of hair cycle by BMP signaling pathway
ontology: BP
definition:
The series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that modulates the rate, frequency or extent of the hair cycle.


go_id: GO:0060903
term: positive regulation of meiosis I
ontology: BP
definition:
Any process that increases the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells.


go_id: GO:0060904
term: regulation of protein folding in endoplasmic reticulum
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of the protein folding process that takes place in the endoplasmic reticulum (ER). Secreted, plasma membrane and organelle proteins are folded in the ER, assisted by chaperones and foldases (protein disulphide isomerases), and additional factors required for optimal folding (ATP, Ca2+ and an oxidizing environment to allow disulfide bond formation).


go_id: GO:0060905
term: regulation of induction of conjugation upon nitrogen starvation
ontology: BP
definition:
Any process that modulates the frequency of induction of conjugation upon nitrogen starvation, the process in which a cell initiates conjugation with cellular fusion upon nitrogen starvation.


go_id: GO:0060906
term: negative regulation of small non-coding RNA-mediated heterochromatin formation
ontology: BP
definition:
Any process that decreases the frequency, rate or extent of small non-coding RNA-mediated heterochromatin formation.


go_id: GO:0060907
term: positive regulation of macrophage cytokine production
ontology: BP
definition:
Any process that increases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0060909
term: regulation of DNA replication initiation involved in plasmid copy number maintenance
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of initiation of plasmid DNA replication that contributes to copy number maintenance.


go_id: GO:0060910
term: negative regulation of DNA replication initiation involved in plasmid copy number maintenance
ontology: BP
definition:
Any process that decreases the frequency, rate or extent of initiation of plasmid DNA replication that contributes to copy number maintenance.


go_id: GO:0060911
term: cardiac cell fate commitment
ontology: BP
definition:
The commitment of cells to specific cardiac cell fates and their capacity to differentiate into cardiac cells. Cardiac cells are cells that comprise the organ which pumps blood through the circulatory system.


go_id: GO:0060912
term: cardiac cell fate specification
ontology: BP
definition:
The process involved in the specification of cardiac cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.


go_id: GO:0060913
term: cardiac cell fate determination
ontology: BP
definition:
The process involved in cardiac cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.


go_id: GO:0060914
term: heart formation
ontology: BP
definition:
The developmental process pertaining to the initial formation of the heart from unspecified parts. This process begins with the specific processes that contribute to the appearance of the heart field and the arrival of cardiac neural crest to the heart region. The process ends when the structural rudiment is recognizable.


go_id: GO:0060915
term: mesenchymal cell differentiation involved in lung development
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the lung. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types.


go_id: GO:0060916
term: mesenchymal cell proliferation involved in lung development
ontology: BP
definition:
The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population that contributes to the progression of the lung over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.


go_id: GO:0060917
term: regulation of (1->6)-beta-D-glucan biosynthetic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->6)-beta-D-glucans.


go_id: GO:0060918
term: auxin transport
ontology: BP
definition:
The directed movement of auxin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Auxins are a group of plant hormones that regulates aspects of plant growth.


go_id: GO:0060920
term: cardiac pacemaker cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a pacemaker cell. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions.


go_id: GO:0060921
term: sinoatrial node cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a sinoatrial (SA) node cell. SA node cells are pacemaker cells that are found in the sinoatrial node.


go_id: GO:0060922
term: atrioventricular node cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of an atrioventricular (AV) node cell. AV node cells are pacemaker cells that are found in the atrioventricular node.


go_id: GO:0060923
term: cardiac muscle cell fate commitment
ontology: BP
definition:
The commitment of cells to specific cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.


go_id: GO:0060924
term: atrial cardiac muscle cell fate commitment
ontology: BP
definition:
The commitment of cells to atrial cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells of the atrium. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.


go_id: GO:0060925
term: ventricular cardiac muscle cell fate commitment
ontology: BP
definition:
The commitment of cells to ventricular cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells of the ventricle. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.


go_id: GO:0060926
term: cardiac pacemaker cell development
ontology: BP
definition:
The process whose specific outcome is the progression of a pacemaker cell over time, from its formation to the mature state. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions.


go_id: GO:0060927
term: cardiac pacemaker cell fate commitment
ontology: BP
definition:
The commitment of cells to pacemaker cell fates and their capacity to differentiate into pacemaker cells. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions.


go_id: GO:0060928
term: atrioventricular node cell development
ontology: BP
definition:
The process whose specific outcome is the progression of an atrioventricular (AV) node cell over time, from its formation to the mature state.


go_id: GO:0060929
term: atrioventricular node cell fate commitment
ontology: BP
definition:
The commitment of cells to atrioventricular (AV) node cell fates and their capacity to differentiate into AV node cells.


go_id: GO:0060930
term: sinoatrial node cell fate commitment
ontology: BP
definition:
The commitment of cells to sinoatrial (SA) node cell fates and their capacity to differentiate into SA node cells. SA node cells are pacemaker cells that are found in the sinoatrial node.


go_id: GO:0060931
term: sinoatrial node cell development
ontology: BP
definition:
The process whose specific outcome is the progression of a sinoatrial (SA) node cell over time, from its formation to the mature state. SA node cells are pacemaker cells that are found in the sinoatrial node.


go_id: GO:0060932
term: His-Purkinje system cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the His-Purkinje system. These cells form the fibers regulate cardiac muscle contraction in the ventricles.


go_id: GO:0060933
term: His-Purkinje system cell development
ontology: BP
definition:
The process whose specific outcome is the progression of a His-Purkinje cell over time, from its formation to the mature state. These cells form the fibers that regulate cardiac muscle contraction in the ventricles.


go_id: GO:0060934
term: His-Purkinje system cell fate commitment
ontology: BP
definition:
The commitment of cells to His-Purkinje cell fates and their capacity to differentiate into His-Purkinje cells. These cells form the fibers that regulate cardiac muscle contraction in the ventricles.


go_id: GO:0060935
term: cardiac fibroblast cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.


go_id: GO:0060936
term: cardiac fibroblast cell development
ontology: BP
definition:
The process whose specific outcome is the progression of a cardiac fibroblast over time, from its formation to the mature state. A cardiac fibroblast is a connective tissue cell of the heart which secretes an extracellular matrix rich in collagen and other macromolecules.


go_id: GO:0060937
term: cardiac fibroblast cell fate commitment
ontology: BP
definition:
The commitment of cells to a cardiac fibroblast fate and their capacity to differentiate into cardiac fibroblast cells. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.


go_id: GO:0060938
term: epicardium-derived cardiac fibroblast cell differentiation
ontology: BP
definition:
The process in which an epicardial cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.


go_id: GO:0060939
term: epicardium-derived cardiac fibroblast cell development
ontology: BP
definition:
The process whose specific outcome is the progression of an epicardial-derived cardiac fibroblast over time, from its formation to the mature state. A epicardial-derived cardiac fibroblast is a connective tissue cell of the heart that arises from the epicardium and secretes an extracellular matrix rich in collagen and other macromolecules.


go_id: GO:0060940
term: epithelial to mesenchymal transition involved in cardiac fibroblast development
ontology: BP
definition:
A transition where an epicardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will mature into a cardiac fibroblast.


go_id: GO:0060941
term: epicardium-derived cardiac fibroblast cell fate commitment
ontology: BP
definition:
The commitment of an epicardial cell to a cardiac fibroblast cell fate and its capacity to differentiate into a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.


go_id: GO:0060942
term: neural crest-derived cardiac fibroblast cell differentiation
ontology: BP
definition:
The process in which a neural crest cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.


go_id: GO:0060943
term: neural crest-derived cardiac fibroblast cell development
ontology: BP
definition:
The process whose specific outcome is the progression of a cardiac fibroblast over time, from its formation from a neural crest cell to the mature state. A cardiac fibroblast is a connective tissue cell of the heart which secretes an extracellular matrix rich in collagen and other macromolecules.


go_id: GO:0060944
term: neural crest-derived cardiac fibroblast cell fate commitment
ontology: BP
definition:
The commitment of neural crest cells to a cardiac fibroblast fate and their capacity to differentiate into cardiac fibroblast cells. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.


go_id: GO:0060945
term: cardiac neuron differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a neuron of the heart.


go_id: GO:0060946
term: cardiac blood vessel endothelial cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell of the heart. Blood vessel endothelial cells are thin flattened cells that line the inside surfaces of blood vessels.


go_id: GO:0060947
term: cardiac vascular smooth muscle cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a cardiac vascular smooth muscle cell. A cardiac vascular smooth muscle cell covers the heart vasculature and lacks transverse striations in its constituent fibers.


go_id: GO:0060948
term: cardiac vascular smooth muscle cell development
ontology: BP
definition:
The process whose specific outcome is the progression of a cardiac vascular smooth muscle cell over time, from its formation to the mature state.


go_id: GO:0060949
term: cardiac vascular smooth muscle cell fate commitment
ontology: BP
definition:
The commitment of cells to a cardiac vascular smooth muscle cell fate and its capacity to differentiate into a cardiac vascular smooth muscle cell.


go_id: GO:0060950
term: cardiac glial cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires the specialized features of a glial cell of the heart.


go_id: GO:0060951
term: neural crest-derived cardiac glial cell differentiation
ontology: BP
definition:
The process in which a neural crest cell acquires the specialized features of a glial cell of the heart.


go_id: GO:0060952
term: cardiac glial cell development
ontology: BP
definition:
The process aimed at the progression of a cardiac glial cell over time, from its formation to the fully functional mature cell.


go_id: GO:0060953
term: cardiac glial cell fate commitment
ontology: BP
definition:
The commitment of cells to cardiac glial cell fates and their capacity to differentiate into cardiac glial cells.


go_id: GO:0060954
term: neural crest-derived cardiac glial cell development
ontology: BP
definition:
The process aimed at the progression of a neural crest-derived cardiac glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.


go_id: GO:0060955
term: neural crest-derived cardiac glial cell fate commitment
ontology: BP
definition:
The commitment of neural crest cells to cardiac glial cell fates and their capacity to differentiate into cardiac glial cells.


go_id: GO:0060956
term: endocardial cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart. The endocardium is the innermost layer of tissue of the heart, and lines the heart chambers.


go_id: GO:0060957
term: endocardial cell fate commitment
ontology: BP
definition:
The commitment of a cell to an endocardial cell fate and its capacity to differentiate into an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart.


go_id: GO:0060958
term: endocardial cell development
ontology: BP
definition:
The progression of an endocardial cell over time, from its formation to the mature cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart.


go_id: GO:0060959
term: cardiac neuron development
ontology: BP
definition:
The process whose specific outcome is the progression of a cardiac neuron over time, from its formation to the mature state.


go_id: GO:0060960
term: cardiac neuron fate commitment
ontology: BP
definition:
The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron of the heart.


go_id: GO:0060962
term: regulation of ribosomal protein gene transcription by RNA polymerase II
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes mediated by RNA polymerase II.


go_id: GO:0060963
term: positive regulation of ribosomal protein gene transcription by RNA polymerase II
ontology: BP
definition:
Any process that increases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes mediated by RNA polymerase II.


go_id: GO:0060964
term: regulation of miRNA-mediated gene silencing
ontology: BP
definition:
A process that modulates the rate, frequency, or extent of the downregulation of gene expression through the action of microRNAs (miRNAs).


go_id: GO:0060966
term: regulation of gene silencing by RNA
ontology: BP
definition:
Any process that regulates the rate, frequency, or extent of gene silencing by RNA. Gene silencing by RNA is the process in which RNA molecules inactivate expression of target genes.


go_id: GO:0060967
term: negative regulation of gene silencing by RNA
ontology: BP
definition:
Any process that decreases the rate, frequency, or extent of gene silencing by RNA. Gene silencing by RNA is the process in which RNA molecules inactivate expression of target genes.


go_id: GO:0060970
term: embryonic heart tube dorsal/ventral pattern formation
ontology: BP
definition:
The regionalization process in which the areas along the dorsal/ventral axis of the embryonic heart tube are established. This process will determine the patterns of cell differentiation along the axis.


go_id: GO:0060971
term: embryonic heart tube left/right pattern formation
ontology: BP
definition:
The pattern specification process that results in the subdivision of the left/right axis of the embryonic heart tube in space to define an area or volume in which specific patterns of cell differentiation will take place.


go_id: GO:0060972
term: left/right pattern formation
ontology: BP
definition:
The pattern specification process that results in the subdivision of the left/right axis in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment.


go_id: GO:0060973
term: cell migration involved in heart development
ontology: BP
definition:
The orderly movement of a cell from one site to another that will contribute to the progression of the heart over time, from its initial formation, to the mature organ.


go_id: GO:0060974
term: cell migration involved in heart formation
ontology: BP
definition:
The orderly movement of a cell from one site to another that contribute to the formation of the heart. The initial heart structure is made up of mesoderm-derived heart progenitor cells and neural crest-derived cells.


go_id: GO:0060975
term: cardioblast migration to the midline involved in heart field formation
ontology: BP
definition:
The orderly movement of a cardioblast toward the midline to form the heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.


go_id: GO:0060976
term: coronary vasculature development
ontology: BP
definition:
The process whose specific outcome is the progression of the blood vessels of the heart over time, from its formation to the mature structure.


go_id: GO:0060977
term: coronary vasculature morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of blood vessels of the heart are generated and organized. The blood vessel is the vasculature carrying blood.


go_id: GO:0060978
term: angiogenesis involved in coronary vascular morphogenesis
ontology: BP
definition:
Blood vessel formation in the heart when new vessels emerge from the proliferation of pre-existing blood vessels.


go_id: GO:0060979
term: vasculogenesis involved in coronary vascular morphogenesis
ontology: BP
definition:
The differentiation of endothelial cells from progenitor cells that contributes to blood vessel development in the heart, and the de novo formation of blood vessels and tubes.


go_id: GO:0060980
term: cell migration involved in coronary vasculogenesis
ontology: BP
definition:
The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form the blood vessels of the heart.


go_id: GO:0060981
term: cell migration involved in coronary angiogenesis
ontology: BP
definition:
The orderly movement of a cell from one site to another that will contribute to the formation of new blood vessels in the heart from pre-existing blood vessels.


go_id: GO:0060982
term: coronary artery morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of coronary arteries are generated and organized. Coronary arteries are blood vessels that transport blood to the heart muscle.


go_id: GO:0060983
term: epicardium-derived cardiac vascular smooth muscle cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell derived from the epicardium acquires specialized features of a cardiac vascular smooth muscle cell. A cardiac vascular smooth muscle cell covers the heart vasculature and lacks transverse striations in its constituent fibers.


go_id: GO:0060984
term: epicardium-derived cardiac vascular smooth muscle cell development
ontology: BP
definition:
The process whose specific outcome is the progression of a cardiac vascular smooth muscle cell that was derived from the epicardium over time, from its formation to the mature state.


go_id: GO:0060985
term: epicardium-derived cardiac vascular smooth muscle cell fate commitment
ontology: BP
definition:
The commitment of an epicardial cell to a cardiac vascular smooth muscle cell fate and its capacity to differentiate into a cardiac vascular smooth muscle cell.


go_id: GO:0060988
term: lipid tube assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as they fuse or undergo fission.


go_id: GO:0060989
term: lipid tube assembly involved in organelle fusion
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as organelles fuse.


go_id: GO:0060990
term: lipid tube assembly involved in organelle fission
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as organelles undergo fission.


go_id: GO:0060992
term: response to fungicide
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fungicide stimulus. Fungicides are chemicals used to kill fungi.


go_id: GO:0060993
term: kidney morphogenesis
ontology: BP
definition:
Morphogenesis of a kidney. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.


go_id: GO:0060995
term: cell-cell signaling involved in kidney development
ontology: BP
definition:
Any process that mediates the transfer of information from one cell to another and contributes to the progression of the kidney over time, from its formation to the mature organ.


go_id: GO:0060996
term: dendritic spine development
ontology: BP
definition:
The process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.


go_id: GO:0060997
term: dendritic spine morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.


go_id: GO:0060998
term: regulation of dendritic spine development
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.


go_id: GO:0060999
term: positive regulation of dendritic spine development
ontology: BP
definition:
Any process that increases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.


go_id: GO:0061000
term: negative regulation of dendritic spine development
ontology: BP
definition:
Any process that decreases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.


go_id: GO:0061001
term: regulation of dendritic spine morphogenesis
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.


go_id: GO:0061002
term: negative regulation of dendritic spine morphogenesis
ontology: BP
definition:
Any process that decreases the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.


go_id: GO:0061003
term: positive regulation of dendritic spine morphogenesis
ontology: BP
definition:
Any process that increases the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.


go_id: GO:0061004
term: pattern specification involved in kidney development
ontology: BP
definition:
Any developmental process that results in the creation of defined areas or spaces within the kidney to which cells respond and eventually are instructed to differentiate.


go_id: GO:0061005
term: cell differentiation involved in kidney development
ontology: BP
definition:
The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the kidney as it progresses from its formation to the mature state.


go_id: GO:0061006
term: regulation of cell proliferation involved in kidney morphogenesis
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of cell proliferation that contributes to the shaping of the kidney.


go_id: GO:0061007
term: hepaticobiliary system process
ontology: BP
definition:
An system process carried out by any of the organs or tissues of the hepaticobiliary system. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins.


go_id: GO:0061008
term: hepaticobiliary system development
ontology: BP
definition:
The progression of the hepaticobiliary system over time, from its formation to the mature structure. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins.


go_id: GO:0061009
term: common bile duct development
ontology: BP
definition:
The progression of the common bile duct over time, from its formation to the mature structure. The common bile duct is formed from the joining of the common hepatic duct running from the liver, and the cystic duct running from the gall bladder. The common bile duct transports bile from the liver and gall bladder to the intestine.


go_id: GO:0061010
term: gall bladder development
ontology: BP
definition:
The progression of the gall bladder over time, from its initial formation to the mature structure. The gall bladder is a cavitated organ that stores bile.


go_id: GO:0061011
term: hepatic duct development
ontology: BP
definition:
The progression of the hepatic duct over time, from its formation to the mature structure. The hepatic duct is the duct that leads from the liver to the common bile duct.


go_id: GO:0061013
term: regulation of mRNA catabolic process
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.


go_id: GO:0061014
term: positive regulation of mRNA catabolic process
ontology: BP
definition:
Any process that increases the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.


go_id: GO:0061017
term: hepatoblast differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a hepatoblast. A hepatoblast is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into hepatocytes and cholangiocytes.


go_id: GO:0061024
term: membrane organization
ontology: BP
definition:
A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.


go_id: GO:0061026
term: cardiac muscle tissue regeneration
ontology: BP
definition:
The regrowth of cardiac muscle tissue to repair injured or damaged muscle fibers in the postnatal stage.


go_id: GO:0061027
term: umbilical cord development
ontology: BP
definition:
The process whose specific outcome is the development of the umbilical cord, from its formation to the mature structure. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta.


go_id: GO:0061028
term: establishment of endothelial barrier
ontology: BP
definition:
The establishment of a barrier between endothelial cell layers, such as those in the brain, lung or intestine, to exert specific and selective control over the passage of water and solutes, thus allowing formation and maintenance of compartments that differ in fluid and solute composition.


go_id: GO:0061029
term: eyelid development in camera-type eye
ontology: BP
definition:
The progression of the eyelid in a camera-type eye from its formation to the mature state. The eyelid is a membranous cover that helps protect and lubricate the eye.


go_id: GO:0061030
term: epithelial cell differentiation involved in mammary gland alveolus development
ontology: BP
definition:
The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland alveolus.


go_id: GO:0061031
term: endodermal digestive tract morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the endodermal digestive tract are generated and organized. The endodermal digestive tract includes those portions of the digestive tract that are derived from endoderm.


go_id: GO:0061032
term: visceral serous pericardium development
ontology: BP
definition:
The progression of the visceral serous pericardium from its formation to the mature structure. The visceral serous pericardium is the inner layer of the pericardium.


go_id: GO:0061033
term: secretion by lung epithelial cell involved in lung growth
ontology: BP
definition:
The controlled release of liquid by a lung epithelial cell that contributes to an increase in size of the lung as part of its development.


go_id: GO:0061034
term: olfactory bulb mitral cell layer development
ontology: BP
definition:
The progression of the olfactory bulb mitral cell layer over time from its initial formation until its mature state. The mitral cell layer is composed of pyramidal neurons whose cell bodies are located between the granule cell layer and the plexiform layer.


go_id: GO:0061035
term: regulation of cartilage development
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.


go_id: GO:0061036
term: positive regulation of cartilage development
ontology: BP
definition:
Any process that increases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.


go_id: GO:0061037
term: negative regulation of cartilage development
ontology: BP
definition:
Any process that decreases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.


go_id: GO:0061041
term: regulation of wound healing
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.


go_id: GO:0061042
term: vascular wound healing
ontology: BP
definition:
Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.


go_id: GO:0061043
term: regulation of vascular wound healing
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.


go_id: GO:0061044
term: negative regulation of vascular wound healing
ontology: BP
definition:
Any process that decreases the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.


go_id: GO:0061045
term: negative regulation of wound healing
ontology: BP
definition:
Any process that decreases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.


go_id: GO:0061046
term: regulation of branching involved in lung morphogenesis
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.


go_id: GO:0061047
term: positive regulation of branching involved in lung morphogenesis
ontology: BP
definition:
Any process that increases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.


go_id: GO:0061048
term: negative regulation of branching involved in lung morphogenesis
ontology: BP
definition:
Any process that decreases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.


go_id: GO:0061049
term: cell growth involved in cardiac muscle cell development
ontology: BP
definition:
The growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.


go_id: GO:0061050
term: regulation of cell growth involved in cardiac muscle cell development
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.


go_id: GO:0061051
term: positive regulation of cell growth involved in cardiac muscle cell development
ontology: BP
definition:
Any process that increases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.


go_id: GO:0061052
term: negative regulation of cell growth involved in cardiac muscle cell development
ontology: BP
definition:
Any process that decreases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.


go_id: GO:0061053
term: somite development
ontology: BP
definition:
The progression of a somite from its initial formation to the mature structure. Somites are mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.


go_id: GO:0061054
term: dermatome development
ontology: BP
definition:
The progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin.


go_id: GO:0061055
term: myotome development
ontology: BP
definition:
The progression of the myotome over time, from its formation to the mature structure. The myotome is the portion of the somite that will give rise to muscle.


go_id: GO:0061056
term: sclerotome development
ontology: BP
definition:
The progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra.


go_id: GO:0061057
term: peptidoglycan recognition protein signaling pathway
ontology: BP
definition:
The series of molecular signals initiated by binding of peptidoglycan to a receptor and ending with regulation of a downstream cellular process. The main outcome of the Imd signaling is the production of antimicrobial peptides.


go_id: GO:0061058
term: regulation of peptidoglycan recognition protein signaling pathway
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway.


go_id: GO:0061059
term: positive regulation of peptidoglycan recognition protein signaling pathway
ontology: BP
definition:
Any process that increases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway.


go_id: GO:0061060
term: negative regulation of peptidoglycan recognition protein signaling pathway
ontology: BP
definition:
Any process that decreases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway.


go_id: GO:0061061
term: muscle structure development
ontology: BP
definition:
The progression of a muscle structure over time, from its formation to its mature state. Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms.


go_id: GO:0061062
term: regulation of nematode larval development
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.


go_id: GO:0061063
term: positive regulation of nematode larval development
ontology: BP
definition:
Any process that increases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.


go_id: GO:0061064
term: negative regulation of nematode larval development
ontology: BP
definition:
Any process that decreases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.


go_id: GO:0061065
term: regulation of dauer larval development
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.


go_id: GO:0061066
term: positive regulation of dauer larval development
ontology: BP
definition:
Any process that increases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.


go_id: GO:0061067
term: negative regulation of dauer larval development
ontology: BP
definition:
Any process that decreases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.


go_id: GO:0061068
term: urethra development
ontology: BP
definition:
The progression of the urethra over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body.


go_id: GO:0061069
term: male urethra development
ontology: BP
definition:
The progression of the male urethra over time from its initial formation to the mature structure. The male urethra is a renal system organ that carries urine from the bladder through the penis to outside the body.


go_id: GO:0061070
term: female urethra development
ontology: BP
definition:
The progression of the female urethra over time from its initial formation to the mature structure. The female urethra is a renal system organ that carries urine from the bladder to outside the body, exiting above the vaginal opening.


go_id: GO:0061071
term: urethra epithelium development
ontology: BP
definition:
The progression of the urethra epithelium over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body. The epithelium is the tubular, planar layer of cells through which the urine passes.


go_id: GO:0061072
term: iris morphogenesis
ontology: BP
definition:
The process in which the iris is generated and organized. The iris is an anatomical structure in the eye whose opening forms the pupil. The iris is responsible for controlling the diameter and size of the pupil and the amount of light reaching the retina.


go_id: GO:0061073
term: ciliary body morphogenesis
ontology: BP
definition:
The process in which the ciliary body generated and organized. The ciliary body is the circumferential tissue inside the eye composed of the ciliary muscle and ciliary processes.


go_id: GO:0061074
term: regulation of neural retina development
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.


go_id: GO:0061075
term: positive regulation of neural retina development
ontology: BP
definition:
Any process that increases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.


go_id: GO:0061076
term: negative regulation of neural retina development
ontology: BP
definition:
Any process that decreases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.


go_id: GO:0061077
term: chaperone-mediated protein folding
ontology: BP
definition:
The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone.


go_id: GO:0061078
term: positive regulation of prostaglandin secretion involved in immune response
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the regulated release of a prostaglandin from a cell and contributes to the immune response.


go_id: GO:0061079
term: left horn of sinus venosus development
ontology: BP
definition:
The progression of the left horn of the sinus venosus from its initial formation to the mature structure.


go_id: GO:0061081
term: positive regulation of myeloid leukocyte cytokine production involved in immune response
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of the production of a cytokine that contributes to the immune response.


go_id: GO:0061083
term: regulation of protein refolding
ontology: BP
definition:
Any process that regulates the rate, frequency, or extent of protein refolding. Protein refolding is the process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.


go_id: GO:0061084
term: negative regulation of protein refolding
ontology: BP
definition:
Any process that decreases the rate, frequency, or extent of protein refolding. Protein refolding is the process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.


go_id: GO:0061085
term: regulation of histone H3-K27 methylation
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone.


go_id: GO:0061086
term: negative regulation of histone H3-K27 methylation
ontology: BP
definition:
Any process that decreases the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone.


go_id: GO:0061087
term: positive regulation of histone H3-K27 methylation
ontology: BP
definition:
Any process that increases the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone.


go_id: GO:0061088
term: regulation of sequestering of zinc ion
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of sequestering of zinc ion. Sequestering of zinc ion is the process of binding or confining zinc ions such that they are separated from other components of a biological system.


go_id: GO:0061089
term: negative regulation of sequestering of zinc ion
ontology: BP
definition:
Any process that decreases the rate, frequency, or extent of sequestering of zinc ion. Sequestering of zinc ion is the process of binding or confining zinc ions such that they are separated from other components of a biological system.


go_id: GO:0061090
term: positive regulation of sequestering of zinc ion
ontology: BP
definition:
Any process that increases the rate, frequency, or extent of sequestering of zinc ion. Sequestering of zinc ion is the process of binding or confining zinc ions such that they are separated from other components of a biological system.


go_id: GO:0061091
term: regulation of phospholipid translocation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.


go_id: GO:0061092
term: positive regulation of phospholipid translocation
ontology: BP
definition:
Any process that increases the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.


go_id: GO:0061093
term: negative regulation of phospholipid translocation
ontology: BP
definition:
Any process that decreases the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.


go_id: GO:0061094
term: regulation of turning behavior involved in mating
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail.


go_id: GO:0061095
term: positive regulation of turning behavior involved in mating
ontology: BP
definition:
Any process that increases the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail.


go_id: GO:0061096
term: negative regulation of turning behavior involved in mating
ontology: BP
definition:
Any process that decreases the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail.


go_id: GO:0061100
term: lung neuroendocrine cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the lung epithelium.


go_id: GO:0061101
term: neuroendocrine cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a neuroendocrine cell. A neuroendocrine cell is a cell that receives input form a neuron which controls the secretion of an endocrine substance.


go_id: GO:0061102
term: stomach neuroendocrine cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the stomach epithelium.


go_id: GO:0061103
term: carotid body glomus cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a glomus cell of the carotid body. The carotid body is a specialized chemosensory organ that helps respond to hypoxia.


go_id: GO:0061104
term: adrenal chromaffin cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an adrenal chromaffin cell. An adrenal chromaffin cell is a neuroendocrine cell that stores epinephrine secretory vesicles.


go_id: GO:0061105
term: regulation of stomach neuroendocrine cell differentiation
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach.


go_id: GO:0061106
term: negative regulation of stomach neuroendocrine cell differentiation
ontology: BP
definition:
Any process that decreases the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach.


go_id: GO:0061107
term: seminal vesicle development
ontology: BP
definition:
The progression of the seminal vesicle over time, from its formation to the mature structure. The seminal vesicle is a gland that contributes to the production of semen.


go_id: GO:0061108
term: seminal vesicle epithelium development
ontology: BP
definition:
The progression of the seminal vesicle epithelium over time, from its formation to the mature structure.


go_id: GO:0061109
term: dense core granule organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a dense core granule. A dense core granule is a secretory organelle found in endocrine cells.


go_id: GO:0061110
term: dense core granule biogenesis
ontology: BP
definition:
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a dense core granule. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the dense core granule.


go_id: GO:0061111
term: epithelial-mesenchymal cell signaling involved in lung development
ontology: BP
definition:
Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell and contributes to the progression of the lung over time from its initial formation to the mature organ.


go_id: GO:0061112
term: negative regulation of bud outgrowth involved in lung branching
ontology: BP
definition:
Any process that decreases the rate, frequency, or extent of bud outgrowth involved in lung branching.


go_id: GO:0061113
term: pancreas morphogenesis
ontology: BP
definition:
Morphogenesis of the pancreas. Morphogenesis is the process in which anatomical structures are generated and organized.


go_id: GO:0061115
term: lung proximal/distal axis specification
ontology: BP
definition:
The establishment, maintenance and elaboration of the proximal/distal axis of the lung. The proximal/distal axis of the lung is defined by a line that runs from the trachea to the alveoli.


go_id: GO:0061116
term: ductus venosus closure
ontology: BP
definition:
The morphogenesis process in which the ductus venosus changes to no longer permit blood flow after birth.


go_id: GO:0061117
term: negative regulation of heart growth
ontology: BP
definition:
Any process that decreases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart.


go_id: GO:0061118
term: regulation of positive chemotaxis to cAMP
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP.


go_id: GO:0061119
term: regulation of positive chemotaxis to cAMP by chlorinated alkylphenone
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions.


go_id: GO:0061120
term: regulation of positive chemotaxis to cAMP by DIF-1
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone.


go_id: GO:0061121
term: regulation of positive chemotaxis to cAMP by DIF-2
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone.


go_id: GO:0061122
term: positive regulation of positive chemotaxis to cAMP
ontology: BP
definition:
Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP.


go_id: GO:0061123
term: negative regulation of positive chemotaxis to cAMP
ontology: BP
definition:
Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP.


go_id: GO:0061124
term: positive regulation of positive chemotaxis to cAMP by chlorinated alkylphenone
ontology: BP
definition:
Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions.


go_id: GO:0061125
term: negative regulation of positive chemotaxis to cAMP by chlorinated alkylphenone
ontology: BP
definition:
Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions.


go_id: GO:0061126
term: positive regulation of positive chemotaxis to cAMP by DIF-1
ontology: BP
definition:
Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone.


go_id: GO:0061127
term: negative regulation of positive chemotaxis to cAMP by DIF-1
ontology: BP
definition:
Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone.


go_id: GO:0061128
term: positive regulation of chemotaxis to cAMP by DIF-2
ontology: BP
definition:
Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone.


go_id: GO:0061129
term: negative regulation of positive chemotaxis to cAMP by DIF-2
ontology: BP
definition:
Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone.


go_id: GO:0061131
term: pancreas field specification
ontology: BP
definition:
The process in which a specific region of the gut is delineated into the area in which the pancreas will develop.


go_id: GO:0061132
term: pancreas induction
ontology: BP
definition:
The close range interaction of two or more cells or tissues that causes the cells of the gut to change their fates and specify the development of the pancreas.


go_id: GO:0061133
term: endopeptidase activator activity
ontology: MF
definition:
Binds to and increases the activity of an endopeptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides.


go_id: GO:0061134
term: peptidase regulator activity
ontology: MF
definition:
Binds to and modulates the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds.


go_id: GO:0061135
term: endopeptidase regulator activity
ontology: MF
definition:
Binds to and modulates the activity of a peptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides.


go_id: GO:0061136
term: regulation of proteasomal protein catabolic process
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome.


go_id: GO:0061137
term: bud dilation
ontology: BP
definition:
The process in which a branch bud increases radially. A branch bud is the initial area of outgrowth in the formation of a new branch.


go_id: GO:0061138
term: morphogenesis of a branching epithelium
ontology: BP
definition:
The process in which the anatomical structures of a branched epithelium are generated and organized.


go_id: GO:0061139
term: bud field specification
ontology: BP
definition:
The regionalization process in which the identity of a bud primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.


go_id: GO:0061140
term: lung secretory cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a lung secretory cell. A lung secretory cell is a specialized epithelial cell of the lung that contains large secretory granules in its apical part.


go_id: GO:0061141
term: lung ciliated cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a lung ciliated cell. A lung ciliated cell is a specialized lung epithelial cell that contains cilia for moving substances released from lung secretory cells.


go_id: GO:0061142
term: mesothelial-mesenchymal cell signaling involved in early lung development
ontology: BP
definition:
Any process that mediates the transfer of information from a mesothelial cell to an epithelial cell and contributes to the development of the lung.


go_id: GO:0061143
term: alveolar primary septum development
ontology: BP
definition:
The progression of a primary alveolar septum over time, from its formation to the mature structure. A primary alveolar septum is a specialized epithelium that surrounds the saccule as it forms.


go_id: GO:0061144
term: alveolar secondary septum development
ontology: BP
definition:
The progression of a secondary alveolar septum over time, from its formation to the mature structure. A secondary alveolar septum is a specialized epithelium that subdivides the initial saccule.


go_id: GO:0061145
term: lung smooth muscle development
ontology: BP
definition:
The process whose specific outcome is the progression of smooth muscle in the lung over time, from its formation to the mature structure.


go_id: GO:0061146
term: Peyer's patch morphogenesis
ontology: BP
definition:
The process in which a Peyer's patch is generated and organized. Peyer's patches are typically found as nodules associated with gut epithelium with distinct internal structures including B- and T-zones for the activation of lymphocytes.


go_id: GO:0061147
term: endocardial endothelium development
ontology: BP
definition:
The progression of the endocardial endothelium over time, from its initial formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.


go_id: GO:0061148
term: extracellular matrix organization involved in endocardium development
ontology: BP
definition:
A process which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix of the endocardium. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.


go_id: GO:0061149
term: BMP signaling pathway involved in ureter morphogenesis
ontology: BP
definition:
The series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to its receptor on the surface of a target cell, which contributes to the shaping of the ureter. The ureter is a tube that extends from the kidney to the bladder.


go_id: GO:0061150
term: renal system segmentation
ontology: BP
definition:
The regionalization process that divides an the renal system into a series of segments along its proximal/distal axis.


go_id: GO:0061151
term: BMP signaling pathway involved in renal system segmentation
ontology: BP
definition:
The series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to its receptor on the surface of a target cell, which contributes to the segmentation of the renal system.


go_id: GO:0061152
term: trachea submucosa development
ontology: BP
definition:
The progression of the trachea submucosa over time from its formation to the mature structure. The trachea submucosa is made up of the glands and elastic tissue that lie under the mucosa in the trachea.


go_id: GO:0061153
term: trachea gland development
ontology: BP
definition:
The progression of a trachea gland over time, from its formation to the mature structure. Trachea glands are found under the mucus of the trachea and secrete mucus, and agents that help protect the lung from injury and infection.


go_id: GO:0061154
term: endothelial tube morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of a tube are generated and organized from an endothelium. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells.


go_id: GO:0061155
term: pulmonary artery endothelial tube morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of a tube are generated and organized from the pulmonary artery endothelium. An pulmonary artery endothelium is an epithelium that lines the pulmonary artery.


go_id: GO:0061156
term: pulmonary artery morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the pulmonary artery are generated and organized. The pulmonary artery is the artery that carries blood from the heart to the lungs.


go_id: GO:0061157
term: mRNA destabilization
ontology: BP
definition:
Any process that decreases the stability of an mRNA molecule, making it more vulnerable to degradative processes. Messenger RNA is the intermediate molecule between DNA and protein. It includes UTR and coding sequences. It does not contain introns.


go_id: GO:0061158
term: 3'-UTR-mediated mRNA destabilization
ontology: BP
definition:
An mRNA destabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA.


go_id: GO:0061159
term: establishment of bipolar cell polarity involved in cell morphogenesis
ontology: BP
definition:
The specification and formation of bipolar intracellular organization or cell growth patterns that contribute to cell morphogenesis. Bipolar organization is the organization that is a mirror image along an axis from a plane.


go_id: GO:0061160
term: regulation of establishment of bipolar cell polarity regulating cell shape
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of the establishment of bipolar cell polarity that contributes to the shape of a cell.


go_id: GO:0061161
term: positive regulation of establishment of bipolar cell polarity regulating cell shape
ontology: BP
definition:
Any process that increases the rate, frequency or extent of the establishment of bipolar cell polarity that regulates the shape of a cell.


go_id: GO:0061162
term: establishment of monopolar cell polarity
ontology: BP
definition:
The specification and formation of monopolar intracellular organization or cell growth patterns. Monopolar cell organization is directional organization along an axis.


go_id: GO:0061163
term: endoplasmic reticulum polarization
ontology: BP
definition:
The endoplasmic reticulum organization process that results in the structure of the endoplasmic reticulum being oriented in the cell. Endoplasmic reticulum polarization serves as a mechanism to compartmentalize cellular activities and to establish cell polarity.


go_id: GO:0061168
term: regulation of hair follicle placode formation
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud.


go_id: GO:0061169
term: positive regulation of hair placode formation
ontology: BP
definition:
Any process that increases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud.


go_id: GO:0061170
term: negative regulation of hair follicle placode formation
ontology: BP
definition:
Any process that decreases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud.


go_id: GO:0061171
term: establishment of bipolar cell polarity
ontology: BP
definition:
The specification and formation of bipolar intracellular organization or cell growth patterns. Bipolar organization is the organization that is a mirror image along an axis from a plane.


go_id: GO:0061172
term: regulation of establishment of bipolar cell polarity
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of the establishment of bipolar cell polarity. Bipolar organization is the organization that is a mirror image along an axis from a plane.


go_id: GO:0061173
term: positive regulation of establishment of bipolar cell polarity
ontology: BP
definition:
Any process that increases the rate, frequency or extent of the establishment of bipolar cell polarity.


go_id: GO:0061174
term: type I terminal bouton
ontology: CC
definition:
Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary to release neurotransmitters that will induce the contraction of muscle. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it.


go_id: GO:0061175
term: type II terminal bouton
ontology: CC
definition:
Terminal inflated portion of the axon of a non-glutamatergic neuron, containing the specialized apparatus necessary to release neurotransmitters at a regulatory synapse. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it.


go_id: GO:0061176
term: type Ib terminal bouton
ontology: CC
definition:
Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary for the tonic release neurotransmitters that will induce the contraction of muscle. Type Ib terminal boutons are larger than type Is terminal boutons.


go_id: GO:0061177
term: type Is terminal bouton
ontology: CC
definition:
Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary for the phasic release neurotransmitters that will induce the contraction of muscle. Type Is terminal boutons are smaller than type Ib terminal boutons.


go_id: GO:0061178
term: regulation of insulin secretion involved in cellular response to glucose stimulus
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.


go_id: GO:0061179
term: negative regulation of insulin secretion involved in cellular response to glucose stimulus
ontology: BP
definition:
Any process that decreases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.


go_id: GO:0061180
term: mammary gland epithelium development
ontology: BP
definition:
The process whose specific outcome is the progression of the mammary gland epithelium over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.


go_id: GO:0061181
term: regulation of chondrocyte development
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate.


go_id: GO:0061182
term: negative regulation of chondrocyte development
ontology: BP
definition:
Any process that decreases the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate.


go_id: GO:0061183
term: regulation of dermatome development
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin.


go_id: GO:0061184
term: positive regulation of dermatome development
ontology: BP
definition:
Any process that increases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin.


go_id: GO:0061185
term: negative regulation of dermatome development
ontology: BP
definition:
Any process that decreases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin.


go_id: GO:0061186
term: negative regulation of silent mating-type cassette heterochromatin formation
ontology: BP
definition:
Any process that decreases the frequency, rate, or extent of heterochromatin formation at silent mating-type cassette.


go_id: GO:0061189
term: positive regulation of sclerotome development
ontology: BP
definition:
Any process that increases the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra.


go_id: GO:0061190
term: regulation of sclerotome development
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra.


go_id: GO:0061191
term: positive regulation of vacuole fusion, non-autophagic
ontology: BP
definition:
Any process that increases the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole.


go_id: GO:0061192
term: negative regulation of vacuole fusion, non-autophagic
ontology: BP
definition:
Any process that decreases the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole.


go_id: GO:0061193
term: taste bud development
ontology: BP
definition:
The progression of the taste bud over time, from its formation to the mature state. The taste bud is a specialized area of the tongue that contains taste receptors.


go_id: GO:0061194
term: taste bud morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the taste bud are generated and organized. The taste bud is a specialized area of the tongue that contains taste receptors.


go_id: GO:0061195
term: taste bud formation
ontology: BP
definition:
The developmental process pertaining to the initial formation of the taste bud from unspecified parts. The taste bud is a specialized area of the tongue that contains taste receptors.


go_id: GO:0061196
term: fungiform papilla development
ontology: BP
definition:
The progression of the fungiform papilla over time, from its formation to the mature structure. The fungiform papilla is a mushroom-shaped papilla of the tongue.


go_id: GO:0061197
term: fungiform papilla morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the fungiform papilla are generated and organized. The fungiform papilla is a mushroom-shaped papilla of the tongue.


go_id: GO:0061198
term: fungiform papilla formation
ontology: BP
definition:
The developmental process pertaining to the initial formation of a spongiform papilla from unspecified parts. The fungiform papilla is a mushroom-shaped papilla of the tongue.


go_id: GO:0061199
term: striated muscle contraction involved in embryonic body morphogenesis
ontology: BP
definition:
The process in which force is generated within striated embryonic muscle tissue, resulting in a contraction of the muscle that contributes to the formation of an embryo's characteristic body morphology.


go_id: GO:0061200
term: clathrin-sculpted gamma-aminobutyric acid transport vesicle
ontology: CC
definition:
A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing gamma-aminobutyric acid transport vesicle.


go_id: GO:0061201
term: clathrin-sculpted gamma-aminobutyric acid transport vesicle lumen
ontology: CC
definition:
The volume enclosed by the membrane of the clathrin-sculpted gamma-aminobutyric acid transport vesicle.


go_id: GO:0061203
term: striated muscle paramyosin thick filament assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of proteins to form the paramyosin-based thick filaments of myofibrils in striated muscle.


go_id: GO:0061205
term: paramesonephric duct development
ontology: BP
definition:
The process whose specific outcome is the progression of the paramesonephric duct over time, from its formation to the mature structure. Mullerian ducts (or paramesonephric ducts) are paired ducts of the embryo that run down the lateral sides of the urogenital ridge and terminate at the mullerian eminence in the primitive urogenital sinus. In the female, they will develop to form the fallopian tubes, uterus, cervix, and the upper portion of the vagina; in the male, they are lost. These ducts are made of tissue of mesodermal origin.


go_id: GO:0061207
term: mesonephric juxtaglomerulus cell differentiation
ontology: BP
definition:
The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the mesonephros as it progresses from its formation to the mature state.


go_id: GO:0061208
term: cell differentiation involved in mesonephros development
ontology: BP
definition:
The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephros as it progresses from its formation to the mature state.


go_id: GO:0061209
term: cell proliferation involved in mesonephros development
ontology: BP
definition:
The multiplication or reproduction of cells, resulting in the expansion of the population in the mesonephros.


go_id: GO:0061210
term: cell-cell signaling involved in mesonephros development
ontology: BP
definition:
Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mesonephros over time, from its formation to the mature organ.


go_id: GO:0061211
term: mesonephric collecting duct development
ontology: BP
definition:
The process whose specific outcome is the progression of a collecting duct in the mesonephros over time, from its formation to the mature structure. The collecting duct regulates water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder.


go_id: GO:0061212
term: mesonephric juxtaglomerular apparatus development
ontology: BP
definition:
The process whose specific outcome is the progression of the juxtaglomerular apparatus in the mesonephros over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate.


go_id: GO:0061213
term: positive regulation of mesonephros development
ontology: BP
definition:
Any process that increases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.


go_id: GO:0061214
term: mesonephric smooth muscle tissue development
ontology: BP
definition:
The process whose specific outcome is the progression of smooth muscle in the mesonephros over time, from its formation to the mature structure.


go_id: GO:0061215
term: mesonephric nephron development
ontology: BP
definition:
The process whose specific outcome is the progression of a nephron in the mesonephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney.


go_id: GO:0061217
term: regulation of mesonephros development
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine.


go_id: GO:0061218
term: negative regulation of mesonephros development
ontology: BP
definition:
Any process that decreases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.


go_id: GO:0061219
term: mesonephric mesenchyme development
ontology: BP
definition:
The biological process whose specific outcome is the progression of a mesonephric mesenchyme from an initial condition to its mature state. This process begins with the formation of mesonephric mesenchyme and ends with the mature structure. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros.


go_id: GO:0061220
term: mesonephric macula densa development
ontology: BP
definition:
The process whose specific outcome is the progression of the mesonephric macula densa over time, from its formation to the mature structure. The mesonephric macula densa is an area of specialized cells in the distal tubule of the mesonephros that makes contact with the vascular pole of the glomerulus.


go_id: GO:0061221
term: mesonephric mesenchyme morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of a mesonephric mesenchymal tissue are generated and organized. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros.


go_id: GO:0061222
term: mesonephric mesenchymal cell proliferation involved in mesonephros development
ontology: BP
definition:
The multiplication or reproduction of cells, resulting in the expansion of a mesonephric mesenchymal cell population.


go_id: GO:0061223
term: mesonephric mesenchymal cell differentiation
ontology: BP
definition:
The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the mesonephros as it progresses from its formation to the mature state.


go_id: GO:0061224
term: mesonephric glomerulus development
ontology: BP
definition:
The progression of the mesonephric glomerulus over time from its initial formation until its mature state. The mesonephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or mesonephros.


go_id: GO:0061225
term: mesonephric extraglomerular mesangial cell proliferation involved in mesonephros development
ontology: BP
definition:
The multiplication or reproduction of extraglomerular glomerular mesangium cells in the mesonephros by cell division, resulting in the expansion of their population. Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa.


go_id: GO:0061226
term: proximal/distal pattern formation involved in mesonephric nephron development
ontology: BP
definition:
The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron in the mesonephros. The proximal/distal axis is defined by a line that runs from the glomerulus (proximal end) outward toward the mesonephric duct (distal end).


go_id: GO:0061227
term: pattern specification involved in mesonephros development
ontology: BP
definition:
Any developmental process that results in the creation of defined areas or spaces within the mesonephros to which cells respond and eventually are instructed to differentiate.


go_id: GO:0061228
term: mesonephric nephron morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the mesonephric nephron are generated and organized. A mesonephric nephron is the functional unit of the mesonephros.


go_id: GO:0061229
term: mesonephric juxtaglomerulus cell development
ontology: BP
definition:
The process whose specific outcome is the progression of a mesonephric juxtaglomerulus cell over time, from its formation to the mature structure.


go_id: GO:0061230
term: mesonephric juxtaglomerulus cell fate commitment
ontology: BP
definition:
The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric juxtaglomerulus cell.


go_id: GO:0061231
term: mesonephric glomerulus vasculature development
ontology: BP
definition:
The biological process whose specific outcome is the progression of a mesonephric glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the mesonephric glomerulus vasculature and ends with the mature structure. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus.


go_id: GO:0061232
term: mesonephric glomerular epithelium development
ontology: BP
definition:
The process whose specific outcome is the progression of the mesonephric glomerular epithelium over time, from its formation to the mature structure. The mesonephric glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus in the mesonephros. The mesonephric glomerular epithelium consists of both parietal and visceral epithelium. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros.


go_id: GO:0061233
term: mesonephric glomerular basement membrane development
ontology: BP
definition:
The process whose specific outcome is the progression of the mesonephric glomerular basement membrane over time, from its formation to the mature structure. The mesonephric glomerular basement membrane is the basal laminal portion of the mesonephric glomerulus which performs the actual filtration.


go_id: GO:0061234
term: mesonephric glomerulus morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the mesonephric glomerulus are generated and organized. The mesonephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate mesonephros.


go_id: GO:0061235
term: mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis
ontology: BP
definition:
The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the mesonephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.


go_id: GO:0061236
term: mesonephric comma-shaped body morphogenesis
ontology: BP
definition:
The process in which the mesonephric comma-shaped body is generated and organized. The mesonephric comma-shaped body is the precursor structure to the mesonephric S-shaped body that contributes to the morphogenesis of a nephron in the mesonephros.


go_id: GO:0061237
term: convergent extension involved in mesonephric nephron morphogenesis
ontology: BP
definition:
The morphogenetic process in which the renal epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to the shaping of a nephron in the mesonephros.


go_id: GO:0061238
term: establishment of planar polarity involved in mesonephric nephron morphogenesis
ontology: BP
definition:
Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron in the mesonephros.


go_id: GO:0061239
term: mesenchymal stem cell differentiation involved in mesonephric nephron morphogenesis
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephronin the mesonephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.


go_id: GO:0061240
term: mesonephric nephron tubule morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of a mesonephric nephron tubule are generated and organized. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros.


go_id: GO:0061241
term: mesonephric nephron epithelium development
ontology: BP
definition:
The process whose specific outcome is the progression of the mesonephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The mesonephric nephron epithelium is a tissue that covers the surface of a nephron in the mesonephros.


go_id: GO:0061242
term: mesonephric nephron tubule development
ontology: BP
definition:
The progression of a mesonephric nephron tubule over time, from its initial formation to the mature structure. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros.


go_id: GO:0061243
term: mesonephric renal vesicle morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the mesonephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the mesonephric nephron epithelium, and is formed by the condensation of mesenchymal cells.


go_id: GO:0061244
term: mesonephric S-shaped body morphogenesis
ontology: BP
definition:
The process in which the mesonephric S-shaped body is generated and organized. The mesonephric S-shaped body is the successor of the mesonephric comma-shaped body that contributes to the morphogenesis of a nephron in the mesonephros.


go_id: GO:0061245
term: establishment or maintenance of bipolar cell polarity
ontology: BP
definition:
Any cellular process that results in the specification, formation or maintenance of a bipolar intracellular organization or cell growth patterns.


go_id: GO:0061246
term: establishment or maintenance of bipolar cell polarity regulating cell shape
ontology: BP
definition:
Any cellular process that results in the specification, formation or maintenance of a bipolar intracellular organization or cell growth patterns that regulates the shaping of a cell.


go_id: GO:0061247
term: mesonephric glomerular mesangium development
ontology: BP
definition:
The process whose specific outcome is the progression of the mesonephric glomerular mesangium over time, from its formation to the mature structure. The mesonephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the mesonephros, which helps to support the capillary loops in a renal glomerulus.


go_id: GO:0061248
term: mesonephric glomerulus vasculature morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the mesonephric glomerulus vasculature are generated and organized. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus.


go_id: GO:0061249
term: mesonephric glomerular capillary formation
ontology: BP
definition:
The process that gives rise to a mesonephric glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts.


go_id: GO:0061250
term: mesonephric glomerular epithelial cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular epithelial cell. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells.


go_id: GO:0061251
term: mesonephric glomerular epithelial cell development
ontology: BP
definition:
The process whose specific outcome is the progression of a mesonephric glomerular epithelial cell over time, from its formation to the mature structure. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells.


go_id: GO:0061252
term: mesonephric glomerular epithelial cell fate commitment
ontology: BP
definition:
The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular epithelial cell. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells.


go_id: GO:0061253
term: mesonephric glomerular parietal epithelial cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular parietal epithelial cell. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.


go_id: GO:0061254
term: mesonephric glomerular parietal epithelial cell development
ontology: BP
definition:
The process whose specific outcome is the progression of a mesonephric glomerular parietal epithelial cell over time, from its formation to the mature structure. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.


go_id: GO:0061255
term: mesonephric glomerular parietal epithelial cell fate commitment
ontology: BP
definition:
The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular parietal epithelial cell. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes.


go_id: GO:0061256
term: mesonephric podocyte differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular visceral epithelial cell. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros.


go_id: GO:0061257
term: mesonephric podocyte development
ontology: BP
definition:
The process whose specific outcome is the progression of a mesonephric glomerular visceral epithelial cell over time, from its formation to the mature structure. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros.


go_id: GO:0061258
term: mesonephric podocyte cell fate commitment
ontology: BP
definition:
The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular visceral epithelial cell. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros.


go_id: GO:0061259
term: mesonephric glomerular mesangial cell differentiation
ontology: BP
definition:
The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the mesonephros as it progresses from its formation to the mature state.


go_id: GO:0061260
term: mesonephric mesangial cell differentiation
ontology: BP
definition:
The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the mesonephros as it progresses from its formation to the mature state.


go_id: GO:0061261
term: mesenchymal to epithelial transition involved in mesonephros morphogenesis
ontology: BP
definition:
A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephros.


go_id: GO:0061263
term: mesonephric glomerular mesangial cell development
ontology: BP
definition:
The process whose specific outcome is the progression of a glomerular mesangial cell in the mesonephros over time, from its formation to the mature structure.


go_id: GO:0061264
term: mesonephric glomerular mesangial cell fate commitment
ontology: BP
definition:
The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular mesangial cell.


go_id: GO:0061265
term: mesonephric nephron tubule epithelial cell differentiation
ontology: BP
definition:
The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephric nephron tubule as it progresses from its formation to the mature state.


go_id: GO:0061266
term: mesonephric interstitial fibroblast differentiation
ontology: BP
definition:
The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblasts of the mesonephros as it progresses from its formation to the mature state.


go_id: GO:0061267
term: mesonephric interstitial fibroblast development
ontology: BP
definition:
The process whose specific outcome is the progression of a mesonephric interstitial fibroblast over time, from its formation to the mature structure.


go_id: GO:0061268
term: mesonephric interstitial fibroblast fate commitment
ontology: BP
definition:
The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric interstitial fibroblast.


go_id: GO:0061269
term: mesonephric glomerular mesangial cell proliferation involved in mesonephros development
ontology: BP
definition:
The multiplication or reproduction of glomerular mesangial cells in the mesonephros, resulting in the expansion of the population.


go_id: GO:0061270
term: mesonephric intraglomerular mesangial cell proliferation
ontology: BP
definition:
The multiplication or reproduction of intraglomerular glomerular mesangium cells in the mesonephros by cell division, resulting in the expansion of their population. Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. They are required for filtration, structural support and phagocytosis.


go_id: GO:0061271
term: mesenchymal to epithelial transition involved in mesonephric renal vesicle formation
ontology: BP
definition:
A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephric renal vesicle.


go_id: GO:0061272
term: mesonephric connecting tubule development
ontology: BP
definition:
The process whose specific outcome is the progression of the mesonephric connecting tubule over time, from its formation to the mature structure. The mesonephric connecting tubule is a tubular segment of the mesonephric nephron; it connects the distal tubule to the collecting duct in the mesonephros.


go_id: GO:0061273
term: mesonephric distal tubule morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of a mesonephric distal tubule are generated and organized. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the macula densa and extends to the mesonephric connecting tubule.


go_id: GO:0061274
term: mesonephric distal tubule development
ontology: BP
definition:
The process whose specific outcome is the progression of the mesonephric distal tubule over time, from its formation to the mature structure. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the terminal segment of the proximal tubule and ends at the mesonephric connecting tubule.


go_id: GO:0061275
term: mesonephric proximal tubule development
ontology: BP
definition:
The progression of the mesonephric proximal tubule over time, from its formation to the mature structure. The mesonephric proximal tubule extends from the capsule to the distal tubule.


go_id: GO:0061276
term: mesonephric proximal tubule morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of a mesonephric proximal tubule are generated and organized. The mesonephric proximal tubule extends from the capsule to the distal tubule.


go_id: GO:0061277
term: mesonephric nephron tubule formation
ontology: BP
definition:
The developmental process pertaining to the initial formation of a mesonephric nephron tubule from unspecified parts. A mesonephric nephron tubule is an epithelial tube that is part of a nephron in the mesonephros.


go_id: GO:0061278
term: epithelial cell migration involved in mesonephric nephron tubule morphogenesis
ontology: BP
definition:
The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric nephron tubule morphogenesis.


go_id: GO:0061279
term: epithelial cell migration involved in mesonephric distal tubule morphogenesis
ontology: BP
definition:
The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric distal tubule morphogenesis.


go_id: GO:0061280
term: epithelial cell migration involved in mesonephric proximal tubule morphogenesis
ontology: BP
definition:
The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric proximal tubule morphogenesis.


go_id: GO:0061282
term: specification of mesonephric nephron tubule identity
ontology: BP
definition:
The process in which the tubules arranged along the proximal/distal axis of the mesonephric nephron acquire their identity.


go_id: GO:0061285
term: mesonephric capsule development
ontology: BP
definition:
The progression of the mesonephric capsule over time, from its formation to the mature structure. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue.


go_id: GO:0061286
term: mesonephric capsule morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the mesonephric capsule are generated and organized. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.


go_id: GO:0061287
term: mesonephric capsule formation
ontology: BP
definition:
The developmental process pertaining to the initial formation of a mesonephric capsule from unspecified parts. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.


go_id: GO:0061288
term: mesonephric capsule specification
ontology: BP
definition:
The regionalization process in which the identity of the mesonephric capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.


go_id: GO:0061289
term: Wnt signaling pathway involved in kidney development
ontology: BP
definition:
The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the kidney over time.


go_id: GO:0061290
term: canonical Wnt signaling pathway involved in metanephric kidney development
ontology: BP
definition:
The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contribute to the progression of the metanephric kidney over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.


go_id: GO:0061291
term: canonical Wnt signaling pathway involved in ureteric bud branching
ontology: BP
definition:
The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the branching of the ureteric bud. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.


go_id: GO:0061292
term: canonical Wnt signaling pathway involved in mesonephros development
ontology: BP
definition:
The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the progression of the mesonephros over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.


go_id: GO:0061293
term: canonical Wnt signaling pathway involved in mesonephric nephron development
ontology: BP
definition:
The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contribute to the progression of the mesonephric nephron over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.


go_id: GO:0061294
term: mesonephric renal vesicle induction
ontology: BP
definition:
Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the mesonephric renal vesicle.


go_id: GO:0061295
term: regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis
ontology: BP
definition:
Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros.


go_id: GO:0061296
ontology: BP
term:
negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis

definition:
Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros.


go_id: GO:0061297
ontology: BP
term:
positive regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis

definition:
Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros.


go_id: GO:0061298
term: retina vasculature development in camera-type eye
ontology: BP
definition:
The process whose specific outcome is the progression of the vasculature of the retina over time, from its formation to the mature structure.


go_id: GO:0061300
term: cerebellum vasculature development
ontology: BP
definition:
The process whose specific outcome is the progression of the vasculature of the cerebellum over time, from its formation to the mature structure.


go_id: GO:0061303
term: cornea development in camera-type eye
ontology: BP
definition:
The progression of the cornea over time, from its formation to the mature structure. The cornea is the transparent structure that covers the anterior of the eye.


go_id: GO:0061304
term: retinal blood vessel morphogenesis
ontology: BP
definition:
The process whose specific outcome is the progression of a blood vessel of the retina over time, from its formation to the mature structure.


go_id: GO:0061305
term: maintenance of bipolar cell polarity regulating cell shape
ontology: BP
definition:
The maintenance of established bipolar anisotropic intracellular organization or cell growth patterns that results in the shaping of a cell.


go_id: GO:0061307
term: cardiac neural crest cell differentiation involved in heart development
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a cardiac neural crest cell that will migrate to the heart and contribute to its development. Cardiac neural crest cells are specialized cells that migrate toward the heart from the third, fourth and sixth pharyngeal arches.


go_id: GO:0061308
term: cardiac neural crest cell development involved in heart development
ontology: BP
definition:
The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the development of the heart.


go_id: GO:0061309
term: cardiac neural crest cell development involved in outflow tract morphogenesis
ontology: BP
definition:
The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the shaping of the outflow tract.


go_id: GO:0061310
ontology: BP
term:
canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development

definition:
The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in cardiac neural crest cell differentiation.


go_id: GO:0061311
term: cell surface receptor signaling pathway involved in heart development
ontology: BP
definition:
The series of molecular signals initiated by a ligand the binding to its receptor on the surface of a cell, which contributes to the progression of the heart over time.


go_id: GO:0061312
term: BMP signaling pathway involved in heart development
ontology: BP
definition:
The series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to its receptor on the surface of a target cell, which contributes to the progression of the heart over time.


go_id: GO:0061313
term: fibroblast growth factor receptor signaling pathway involved in heart development
ontology: BP
definition:
The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands and contributing to the progression of the heart over time.


go_id: GO:0061314
term: Notch signaling involved in heart development
ontology: BP
definition:
The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell and contributing to the progression of the heart over time.


go_id: GO:0061315
ontology: BP
term:
canonical Wnt signaling pathway involved in positive regulation of cardiac muscle cell proliferation

definition:
The canonical Wnt signaling pathway that contributes to an expansion of the population of cardiac muscle cells.


go_id: GO:0061316
term: canonical Wnt signaling pathway involved in heart development
ontology: BP
definition:
The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the progression of the heart over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.


go_id: GO:0061317
term: canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment
ontology: BP
definition:
The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin and contributing to cardiac muscle cell fate commitment. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.


go_id: GO:0061318
term: renal filtration cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a renal filtration cell. Renal filtration cells are specialized cells of the renal system that filter fluids by charge, size or both. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.


go_id: GO:0061319
term: nephrocyte differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a nephrocyte. A nephrocyte is an insect renal cell that filters hemolymph. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.


go_id: GO:0061320
term: pericardial nephrocyte differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a pericardial nephrocyte. A pericardial nephrocyte is an insect renal cell that filters hemolymph and is found with other pericardial nephrocytes in two rows flanking the dorsal vessel. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.


go_id: GO:0061321
term: garland nephrocyte differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a garland nephrocyte. A garland nephrocyte is an insect renal cell that filters hemolymph and forms a ring with other garland nephrocytes around the esophagus. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.


go_id: GO:0061322
term: disseminated nephrocyte differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a disseminated nephrocyte. A disseminated nephrocyte is an insect renal cell that filters hemolymph and is found at scattered locations in the fat body or other tissues. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.


go_id: GO:0061323
term: cell proliferation involved in heart morphogenesis
ontology: BP
definition:
The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the heart.


go_id: GO:0061324
ontology: BP
term:
canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation

definition:
The canonical Wnt signaling pathway that contributes to the modulation of the expansion of a population of cardiac outflow tract cells.


go_id: GO:0061325
term: cell proliferation involved in outflow tract morphogenesis
ontology: BP
definition:
The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the outflow tract.


go_id: GO:0061326
term: renal tubule development
ontology: BP
definition:
The progression of the renal tubule over time from its formation to the mature form. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis.


go_id: GO:0061327
term: anterior Malpighian tubule development
ontology: BP
definition:
The process whose specific outcome is the progression of the anterior Malpighian tubule over time, from its formation to the mature structure. The pair of anterior tubules arise from a dorsal region of the embryonic hindgut and projects forwards through the body cavity. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which connects with the posterior part of the gut.


go_id: GO:0061328
term: posterior Malpighian tubule development
ontology: BP
definition:
The process whose specific outcome is the progression of the posterior Malpighian tubule over time, from its formation to the mature structure. The pair of posterior tubules arise from a ventrolateral region of the embryonic hindgut and project backwards through the body cavity. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which connects with the posterior part of the gut.


go_id: GO:0061329
term: Malpighian tubule principal cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule principal cell. A Malpighian tubule principal cell is an epithelial secretory cell that transports cations into the lumen of the tubule.


go_id: GO:0061330
term: Malpighian tubule stellate cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule stellate cell. A Malpighian tubule stellate cell is a specialized epithelial secretory cell that moves chloride ions and water across the tubule epithelium.


go_id: GO:0061331
term: epithelial cell proliferation involved in Malpighian tubule morphogenesis
ontology: BP
definition:
The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population and contributing to the shaping of a Malpighian tubule.


go_id: GO:0061332
term: Malpighian tubule bud morphogenesis
ontology: BP
definition:
The morphogenetic process in which a bud forms from the embryonic hindgut tube to form the Malpighian tubule. A bud is a protrusion that forms from the tube by localized changes in cell shape and position.


go_id: GO:0061333
term: renal tubule morphogenesis
ontology: BP
definition:
The process in which the renal tubule is generated by specification of cell fate, through the maintenance of cell polarity, regulated cell proliferation and morphogenetic cell rearrangements, shape changes and growth. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis.


go_id: GO:0061334
term: cell rearrangement involved in Malpighian tubule morphogenesis
ontology: BP
definition:
The movement of an epithelial cell with respect to other epithelial cells that contributes to the shaping of the Malpighian tubule.


go_id: GO:0061335
term: cell growth involved in Malpighian tubule morphogenesis
ontology: BP
definition:
The growth of an epithelial cell dependent on cycles of endoreplication, where growth contributes to the shaping of the Malpighian tubule.


go_id: GO:0061336
term: cell morphogenesis involved in Malpighian tubule morphogenesis
ontology: BP
definition:
The shape change of an epithelial cell from a columnar to squamous cell morphology that contributes to the shaping of the Malpighian tubule.


go_id: GO:0061337
term: cardiac conduction
ontology: BP
definition:
Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles.


go_id: GO:0061339
term: establishment or maintenance of monopolar cell polarity
ontology: BP
definition:
Any cellular process that results in the specification, formation or maintenance of monopolar intracellular organization or cell growth patterns. Monopolar cell organization is directional organization along an axis.


go_id: GO:0061340
term: establishment or maintenance of monopolar cell polarity regulating cell shape
ontology: BP
definition:
Any cellular process that results in the specification, formation or maintenance of a monopolar intracellular organization or cell growth patterns that regulate the shape of a cell.


go_id: GO:0061341
term: non-canonical Wnt signaling pathway involved in heart development
ontology: BP
definition:
The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin and contributing to the progression of the heart over time.


go_id: GO:0061342
term: regulation of cell adhesion involved in heart morphogenesis by non-canonical Wnt signaling pathway
ontology: BP
definition:
Any process that decreased the extent of cell adhesion that contributes to the shaping of the heart.


go_id: GO:0061343
term: cell adhesion involved in heart morphogenesis
ontology: BP
definition:
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the shaping of the heart.


go_id: GO:0061345
term: planar cell polarity pathway involved in cardiac muscle cell fate commitment
ontology: BP
definition:
The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin and contributing to a cardioblast being committed to a cardiac muscle cell fate.


go_id: GO:0061346
term: planar cell polarity pathway involved in heart morphogenesis
ontology: BP
definition:
The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the heart.


go_id: GO:0061347
term: planar cell polarity pathway involved in outflow tract morphogenesis
ontology: BP
definition:
The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the outflow tract.


go_id: GO:0061348
term: planar cell polarity pathway involved in ventricular septum morphogenesis
ontology: BP
definition:
The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the ventricular septum.


go_id: GO:0061349
term: planar cell polarity pathway involved in cardiac right atrium morphogenesis
ontology: BP
definition:
The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the cardiac right atrium.


go_id: GO:0061350
term: planar cell polarity pathway involved in cardiac muscle tissue morphogenesis
ontology: BP
definition:
The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the cardiac muscle tissue.


go_id: GO:0061351
term: neural precursor cell proliferation
ontology: BP
definition:
The multiplication or reproduction of neural precursor cells, resulting in the expansion of a cell population. A neural precursor cell is either a nervous system stem cell or a nervous system progenitor cell.


go_id: GO:0061352
term: cell chemotaxis involved in Malpighian tubule morphogenesis
ontology: BP
definition:
The directed movement of the outgrowing Malpighian tubule guided by specific chemical cues/signals. Movement may be towards a guidance cue (positive chemotaxis) or away from it (negative chemotaxis). Guidance contributes to the final positioning of the tubule.


go_id: GO:0061353
term: BMP signaling pathway involved in Malpighian tubule cell chemotaxis
ontology: BP
definition:
The series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to its receptor on the surface of a target cell, which contributes to the directed movement of a Malpighian tubule cell toward a stimulus, thereby contributing to the shaping of the tubule.


go_id: GO:0061354
term: planar cell polarity pathway involved in pericardium morphogenesis
ontology: BP
definition:
The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the pericardium.


go_id: GO:0061356
term: regulation of Wnt protein secretion
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the controlled release of a Wnt protein from a cell.


go_id: GO:0061357
term: positive regulation of Wnt protein secretion
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the controlled release of a Wnt protein from a cell.


go_id: GO:0061358
term: negative regulation of Wnt protein secretion
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a Wnt protein from a cell.


go_id: GO:0061359
term: regulation of Wnt signaling pathway by Wnt protein secretion
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the activity of the Wnt signaling pathway by the controlled release of a Wnt protein from a cell.


go_id: GO:0061360
term: optic chiasma development
ontology: BP
definition:
The developmental process pertaining to the progression of the optic chiasm from its initial formation to the mature structure. The process begins when the pathfinding of the axons of the developing optic nerve cause some axons to cross at the midline of the brain and ends when the axons are mature.


go_id: GO:0061361
term: positive regulation of maintenance of bipolar cell polarity regulating cell shape
ontology: BP
definition:
Any process that increases the frequency, rate or extent of maintenance of bipolar cell polarity regulating cell shape.


go_id: GO:0061362
term: negative regulation of maintenance of bipolar cell polarity regulating cell shape
ontology: BP
definition:
Any process that decreases the frequency, rate or extent of maintenance of bipolar cell polarity regulating cell shape.


go_id: GO:0061363
term: negative regulation of progesterone biosynthesis involved in luteolysis
ontology: BP
definition:
Any process that decreases the rate, frequency or extent of the biosynthesis of progesterone biosynthesis that contributes to luteolysis.


go_id: GO:0061366
term: behavioral response to chemical pain
ontology: BP
definition:
Any process that results in a change in the behaviour of an organism as a result of a chemical pain stimulus.


go_id: GO:0061367
term: behavioral response to acetic acid induced pain
ontology: BP
definition:
Any process that results in a change in the behaviour of an organism as a result of an acetic acid pain stimulus.


go_id: GO:0061368
term: behavioral response to formalin induced pain
ontology: BP
definition:
Any process that results in a change in the behaviour of an organism as a result of a formalin pain stimulus.


go_id: GO:0061369
term: negative regulation of testicular blood vessel morphogenesis
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis in the testicle.


go_id: GO:0061370
term: testosterone biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of testosterone, an androgen having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4 C-5.


go_id: GO:0061371
term: determination of heart left/right asymmetry
ontology: BP
definition:
Determination of the asymmetric location of the heart with respect to the left and right halves of the organism.


go_id: GO:0061372
term: activin receptor signaling pathway involved in heart jogging
ontology: BP
definition:
The series of molecular signals initiated by the binding of a member of the activin family to its receptor on the surface of a target cell, and contributing to the process of heart jogging.


go_id: GO:0061373
term: mammillary axonal complex development
ontology: BP
definition:
The progression of the mammillary axonal complex over time, from its formation to the mature structure. The mammillary axonal complex is formed by the axons from the lateral, medial mammillary and the dorsal premammillary nuclei which share a branching pattern. Every neuron gives off one axonal stem that bifurcates into 2 branches. One of the branches is directed dorsally to the thalamus and another caudally to the midbrain.


go_id: GO:0061374
term: mammillothalamic axonal tract development
ontology: BP
definition:
The progression of the mammillothalamic axonal tract, from its formation to the mature structure. The mammillothalamic tract is the collection of axons that connects the two major subdivisions of the diencephalon (hypothalamus and thalamus) and closes the diencephalic circuit.


go_id: GO:0061375
term: mammillotectal axonal tract development
ontology: BP
definition:
The progression of the mammillotectal tract over time, from its formation to the mature structure. The mammillotectal tract is the collection of axons that connects the ventral diencephalon to the superior colliculus.


go_id: GO:0061376
term: mammillotegmental axonal tract development
ontology: BP
definition:
The process in which the mammillotegmental tract progresses over time, from its formation to the mature structure. The mammillotegmental tract is the collection of axons that connects the ventral diencephalon to the tegmentum and pons.


go_id: GO:0061377
term: mammary gland lobule development
ontology: BP
definition:
The progression of the mammary gland lobule over time, from its formation to the mature structure. A mammary gland lobule is a small rounded projection of the mammary gland.


go_id: GO:0061378
term: corpora quadrigemina development
ontology: BP
definition:
The progression of the corpora quadrigemina over time, from its formation to the mature structure. The corpora quadrigemina is a part of the midbrain that is made up of the superior and inferior colliculi.


go_id: GO:0061379
term: inferior colliculus development
ontology: BP
definition:
The process whose specific outcome is the progression of the inferior colliculus over time, from its formation to the mature structure. The inferior colliculus (IC) (Latin, lower hill) is the principal midbrain nucleus of the auditory pathway and receives input from several more peripheral brainstem nuclei in the auditory pathway, as well as inputs from the auditory cortex. The inferior colliculus has three subdivisions: the central nucleus (CIC), a dorsal cortex (DCIC) by which it is surrounded, and an external cortex (ICX) which is located laterally.


go_id: GO:0061380
term: superior colliculus development
ontology: BP
definition:
The process whose specific outcome is the progression of the superior colliculus over time, from its formation to the mature structure. The superior colliculus is also known as the optic tectum or simply tectum and is a paired structure that forms a major component of the vertebrate midbrain.


go_id: GO:0061382
term: Malpighian tubule tip cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule tip cell. A Malpighian tubule tip cell is a mitogenic signaling cell that controls the proliferation of its neighboring cells.


go_id: GO:0061383
term: trabecula morphogenesis
ontology: BP
definition:
The process of shaping a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue.


go_id: GO:0061384
term: heart trabecula morphogenesis
ontology: BP
definition:
The process of shaping a trabecula in the heart. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue.


go_id: GO:0061385
term: fibroblast proliferation involved in heart morphogenesis
ontology: BP
definition:
The multiplication or reproduction of fibroblasts, resulting in the expansion of a fibroblast population that contributes to the shaping of the heart.


go_id: GO:0061394
ontology: BP
term:
regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance

definition:
Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides.


go_id: GO:0061395
ontology: BP
term:
positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance

definition:
Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides.


go_id: GO:0061399
term: positive regulation of transcription from RNA polymerase II promoter in response to cobalt ion
ontology: BP
definition:
Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to a cobalt ion stimulus.


go_id: GO:0061400
term: positive regulation of transcription from RNA polymerase II promoter in response to calcium ion
ontology: BP
definition:
Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to a calcium ion stimulus.


go_id: GO:0061402
term: positive regulation of transcription from RNA polymerase II promoter in response to acidic pH
ontology: BP
definition:
Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a pH stimulus with pH < 7.


go_id: GO:0061403
ontology: BP
term:
positive regulation of transcription from RNA polymerase II promoter in response to nitrosative stress

definition:
Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions.


go_id: GO:0061405
ontology: BP
term:
positive regulation of transcription from RNA polymerase II promoter in response to hydrostatic pressure

definition:
Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hydrostatic pressure stimulus. Hydrostatic pressure is the force acting on an object in a system where the fluid is at rest (as opposed to moving). The weight of the fluid above the object creates pressure on it.


go_id: GO:0061406
ontology: BP
term:
positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation

definition:
Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of glucose.


go_id: GO:0061407
ontology: BP
term:
positive regulation of transcription from RNA polymerase II promoter in response to hydrogen peroxide

definition:
Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hydrogen peroxide (H2O2) stimulus.


go_id: GO:0061408
term: positive regulation of transcription from RNA polymerase II promoter in response to heat stress
ontology: BP
definition:
Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.


go_id: GO:0061409
term: positive regulation of transcription from RNA polymerase II promoter in response to freezing
ontology: BP
definition:
Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a freezing stimulus, temperatures below 0 degrees Celsius.


go_id: GO:0061410
term: positive regulation of transcription from RNA polymerase II promoter in response to ethanol
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an ethanol stimulus.


go_id: GO:0061411
term: positive regulation of transcription from RNA polymerase II promoter in response to cold
ontology: BP
definition:
Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.


go_id: GO:0061412
ontology: BP
term:
positive regulation of transcription from RNA polymerase II promoter in response to amino acid starvation

definition:
Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of amino acids.


go_id: GO:0061413
term: regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source
ontology: BP
definition:
A transcription regulation process in which the presence of a nonfermentable carbon source leads to the modulation of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources.


go_id: GO:0061414
ontology: BP
term:
positive regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source

definition:
A transcription regulation process in which the presence of a nonfermentable carbon source leads to an increase of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources.


go_id: GO:0061415
ontology: BP
term:
negative regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source

definition:
A transcription regulation process in which the presence of a nonfermentable carbon source leads to a decrease of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources.


go_id: GO:0061417
ontology: BP
term:
negative regulation of transcription from RNA polymerase II promoter in response to oxidative stress

definition:
Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.


go_id: GO:0061418
term: regulation of transcription from RNA polymerase II promoter in response to hypoxia
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus.


go_id: GO:0061419
term: positive regulation of transcription from RNA polymerase II promoter in response to hypoxia
ontology: BP
definition:
Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus.


go_id: GO:0061420
term: regulation of transcription from RNA polymerase II promoter in response to biotin starvation
ontology: BP
definition:
Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of biotin.


go_id: GO:0061422
term: positive regulation of transcription from RNA polymerase II promoter in response to alkaline pH
ontology: BP
definition:
Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a pH >7.0.


go_id: GO:0061425
ontology: BP
term:
positive regulation of ethanol catabolic process by positive regulation of transcription from RNA polymerase II promoter

definition:
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter and activates or increases the frequency, rate or extent of an ethanol catabolic process.


go_id: GO:0061428
term: negative regulation of transcription from RNA polymerase II promoter in response to hypoxia
ontology: BP
definition:
Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus.


go_id: GO:0061429
term: positive regulation of transcription from RNA polymerase II promoter by oleic acid
ontology: BP
definition:
Any process involving oleic acid that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.


go_id: GO:0061430
term: bone trabecula morphogenesis
ontology: BP
definition:
The process of shaping a trabecula in bone. A trabecula is a tissue element in the form of a small beam, strut or rod.


go_id: GO:0061431
term: cellular response to methionine
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methionine stimulus.


go_id: GO:0061433
term: cellular response to caloric restriction
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a of caloric restriction, insufficient food energy intake.


go_id: GO:0061435
term: positive regulation of transcription from a mobile element promoter
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of transcription from a mobile element promoter.


go_id: GO:0061436
term: establishment of skin barrier
ontology: BP
definition:
Establishment of the epithelial barrier, the functional barrier in the skin that limits its permeability.


go_id: GO:0061437
term: renal system vasculature development
ontology: BP
definition:
The process whose specific outcome is the progression of vasculature of the renal system over time, from its formation to the mature structure.


go_id: GO:0061438
term: renal system vasculature morphogenesis
ontology: BP
definition:
The process in which the renal system vasculature is generated and organized. Morphogenesis pertains to the creation of form.


go_id: GO:0061439
term: kidney vasculature morphogenesis
ontology: BP
definition:
The process in which the kidney vasculature is generated and organized. Morphogenesis pertains to the creation of form.


go_id: GO:0061440
term: kidney vasculature development
ontology: BP
definition:
The process whose specific outcome is the progression of the vasculature of the kidney over time, from its formation to the mature structure.


go_id: GO:0061441
term: renal artery morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of a renal artery is generated and organized. Renal arteries supply the kidneys with blood.


go_id: GO:0061442
term: cardiac muscle cell fate determination
ontology: BP
definition:
The process involved in cardiac muscle cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.


go_id: GO:0061443
term: endocardial cushion cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cushion cell.


go_id: GO:0061444
term: endocardial cushion cell development
ontology: BP
definition:
The process whose specific outcome is the progression of an endocardial cushion cell over time, from its formation to the mature state.


go_id: GO:0061445
term: endocardial cushion cell fate commitment
ontology: BP
definition:
The commitment of a cell to an endocardial cushion cell fate and its capacity to differentiate into an endocardial cushion cell.


go_id: GO:0061446
term: endocardial cushion cell fate determination
ontology: BP
definition:
The process involved in endocardial cushion cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.


go_id: GO:0061447
term: endocardial cushion cell fate specification
ontology: BP
definition:
The process involved in the specification of endocardial cushion cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.


go_id: GO:0061449
term: olfactory bulb tufted cell development
ontology: BP
definition:
The process whose specific outcome is the progression of an olfactory bulb tufted cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.


go_id: GO:0061450
term: trophoblast cell migration
ontology: BP
definition:
Trophoblast cell migration that is accomplished by extension and retraction of a pseudopodium. Trophoblast cells line the outside of the blastocyst.


go_id: GO:0061451
term: retrotrapezoid nucleus development
ontology: BP
definition:
The progression of the retrotrapezoid nucleus (RTN) over time from it's initial formation to its mature state. The retrotrapezoid nucleus is a group of neurons in the rostral medulla, which are responsible regulating respiration.


go_id: GO:0061452
term: retrotrapezoid nucleus neuron differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the retrotrapezoid nucleus.


go_id: GO:0061453
term: interstitial cell of Cajal differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of an interstitial cell of Cajal. An interstitial cell of Cajal is an intestinal neuroepithelial cell that serves as a pacemaker to trigger gut contraction.


go_id: GO:0061455
term: integral component of muscle cell projection membrane
ontology: CC
definition:
The component of the muscle cell projection membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.


go_id: GO:0061456
term: mesenchymal stem cell migration involved in uteric bud morphogenesis
ontology: BP
definition:
The orderly movement of a mesenchymal stem cell from one site to another contributing to the shaping of the ureteric bud. A mesenchymal stem cell, or MSC, is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.


go_id: GO:0061457
term: mesonephric cell migration involved in male gonad development
ontology: BP
definition:
The orderly movement of a cell from the mesonephros to the male gonad, contributing to its development.


go_id: GO:0061458
term: reproductive system development
ontology: BP
definition:
The progression of the reproductive system over time from its formation to the mature structure. The reproductive system consists of the organs that function in reproduction.


go_id: GO:0061468
term: karyomere
ontology: CC
definition:
A membrane-bound intermediate cleavage-stage structure of individual or groups of chromosomes that coalesces and fuses with other karyomeres to form a nucleus during interphase. Karyomere formation occurs in blastomeres undergoing rapid cell division.


go_id: GO:0061470
term: T follicular helper cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized T cell acquires specialized features of a mature T follicular helper cell.


go_id: GO:0061471
term: karyomere assembly
ontology: BP
definition:
The process where the nuclear membrane engulfs condensed chromosomes to form karyomeres during M phase of the mitotic cell cycle.


go_id: GO:0061473
term: murein tripeptide carboxypeptidase activity
ontology: MF
definition:
Catalysis of the reaction L-Ala-gamma-D-Glu-meso-Dap (murein tripeptide) + H2O = L-Ala-gamma-D-Glu + meso-diaminopimelate.


go_id: GO:0061475
term: cytosolic valyl-tRNA aminoacylation
ontology: BP
definition:
The process of coupling valine to valyl-tRNA in the cytosol, catalyzed by valyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.


go_id: GO:0061476
term: response to anticoagulant
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anticoagulant stimulus.


go_id: GO:0061477
term: response to aromatase inhibitor
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aromatase inhibitor stimulus.


go_id: GO:0061478
term: response to platelet aggregation inhibitor
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet aggregation inhibitor stimulus.


go_id: GO:0061479
term: response to reverse transcriptase inhibitor
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reverse transcriptase inhibitor stimulus.


go_id: GO:0061480
term: response to asparaginase
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an asparaginase stimulus.


go_id: GO:0061481
term: response to TNF agonist
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a TNF agonist stimulus.


go_id: GO:0061482
term: response to irinotecan
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an irinotecan stimulus.


go_id: GO:0061483
term: sulfinylpropanyl adenylate synthase
ontology: MF
definition:
Catalysis of the reaction: cysteine sulfanate + GTP + IMP = sulfinylpropanyl adenylate + GDP + 3 H(+) + phosphate.


go_id: GO:0061484
term: hematopoietic stem cell homeostasis
ontology: BP
definition:
Any biological process involved in the maintenance of the steady-state number of hematopoietic stem cells within a population of cells.


go_id: GO:0061486
term: high-affinity fructose transmembrane transporter activity
ontology: MF
definition:
Enables the transfer of fructose from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.


go_id: GO:0061492
term: asymmetric protein localization to old or new spindle pole body
ontology: BP
definition:
Any process in which a protein is transported to, or maintained to either the old or new spindle pole body resulting in its being distributed asymmetrically.


go_id: GO:0061493
term: central plaque of mitotic spindle pole body
ontology: CC
definition:
One of three laminate structures that form the mitotic spindle pole body; the inner plaque is on the nuclear face of the spindle pole body.


go_id: GO:0061497
term: inner plaque of mitotic spindle pole body
ontology: CC
definition:
One of three laminate structures that form the mitotic spindle pole body; the inner plaque is in the nucleus.


go_id: GO:0061499
term: outer plaque of mitotic spindle pole body
ontology: CC
definition:
One of three laminate structures that form the mitotic spindle pole body; the outer plaque is in the cytoplasm.


go_id: GO:0061501
term: 2',3'-cyclic GMP-AMP synthase activity
ontology: MF
definition:
Catalysis of the reaction: ATP + GTP = 2 diphosphate + cyclic G-P(2'-5')A-P(3'-5') (cyclic 2',3' GAMP).


go_id: GO:0061502
term: early endosome to recycling endosome transport
ontology: BP
definition:
The directed movement of substances, in membrane-bounded vesicles, from the early sorting endosomes to the recycling endosomes.


go_id: GO:0061504
term: cyclic threonylcarbamoyladenosine biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of cyclic threonylcarbamoyladenosine, a modified nucleoside found in some tRNA molecules.


go_id: GO:0061507
term: 2',3'-cyclic GMP-AMP binding
ontology: MF
definition:
Binding to 2',3' cyclic GMP-AMP (cGAMP) nucleotide, a cyclic purine dinucleotide that consists of AMP and GMP units cyclized via 2',5' and 3',5' linkages.


go_id: GO:0061509
term: asymmetric protein localization to old mitotic spindle pole body
ontology: BP
definition:
Any process in which a protein is transported to, or maintained to the old mitotic spindle pole body resulting in its being distributed asymmetrically.


go_id: GO:0061510
term: asymmetric protein localization to new mitotic spindle pole body
ontology: BP
definition:
Any process in which a protein is transported to, or maintained to the new mitotic spindle pole body resulting in its being distributed asymmetrically.


go_id: GO:0061511
term: centriole elongation
ontology: BP
definition:
The centrosome organization process by which a centriole increases in length as part of the process of replication.


go_id: GO:0061513
term: glucose 6-phosphate:inorganic phosphate antiporter activity
ontology: MF
definition:
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose 6-phosphate(out) + inorganic phosphate(in) = glucose 6-phosphate(in) + inorganic phosphate(out).


go_id: GO:0061514
term: interleukin-34-mediated signaling pathway
ontology: BP
definition:
The series of molecular signals initiated by interleukin-34 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


go_id: GO:0061515
term: myeloid cell development
ontology: BP
definition:
The process whose specific outcome is the progression of a myeloid cell over time, from its formation to the mature structure.


go_id: GO:0061519
term: macrophage homeostasis
ontology: BP
definition:
The process of regulating the proliferation and elimination of macrophage cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.


go_id: GO:0061521
term: hepatic stellate cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a hepatic stellate cell.


go_id: GO:0061524
term: central canal development
ontology: BP
definition:
The process whose specific outcome is the formation of the central canal of the spinal cord from its formation to the mature structure. The central canal is a spinal cord structure that is part of the ventricular system and is filled with cerebral-spinal fluid and runs the length of the spinal cord.


go_id: GO:0061525
term: hindgut development
ontology: BP
definition:
The process whose specific outcome is the progression of the hindgut over time, from its formation to the mature structure. The hindgut is part of the alimentary canal that lies posterior to the midgut.


go_id: GO:0061532
term: primary amine secretion, neurotransmission
ontology: BP
definition:
The regulated release of a primary amine by a cell, in which the primary amine acts as a neurotransmitter.


go_id: GO:0061533
term: norepinephrine secretion, neurotransmission
ontology: BP
definition:
The regulated release of norepinephrine by a cell, in which the norepinephrine acts as a neurotransmitter.


go_id: GO:0061534
term: gamma-aminobutyric acid secretion, neurotransmission
ontology: BP
definition:
The regulated release of gamma-aminobutyric acid by a cell, in which the gamma-aminobutyric acid acts as a neurotransmitter.


go_id: GO:0061541
term: rhabdomere morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of a rhabdomere are generated and organized. The rhabdomere is the organelle on the apical surface of a photoreceptor cell that contains the visual pigments.


go_id: GO:0061542
term: 3-demethylubiquinol-n 3-O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinol-n = S-adenosyl-L-homocysteine + ubiquinol-n.


go_id: GO:0061543
term: 3-demethylubiquinol-6 3-O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinol-6 = S-adenosyl-L-homocysteine + ubiquinol-6.


go_id: GO:0061547
term: glycogen synthase activity, transferring glucose-1-phosphate
ontology: MF
definition:
Catalysis of the reaction: UDP-glucose + (1,4)-alpha-D-glucosyl(n) = UMP + (1,4)-alpha-D-glucosyl(n)-glucose-1-phosphate.


go_id: GO:0061548
term: ganglion development
ontology: BP
definition:
The process whose specific outcome is the progression of a ganglion over time, from its formation to the mature structure.


go_id: GO:0061549
term: sympathetic ganglion development
ontology: BP
definition:
The process whose specific outcome is the progression of a sympathetic ganglion over time, from its formation to the mature structure.


go_id: GO:0061550
term: cranial ganglion development
ontology: BP
definition:
The process whose specific outcome is the progression of a cranial ganglion over time, from its formation to the mature structure.


go_id: GO:0061551
term: trigeminal ganglion development
ontology: BP
definition:
The process whose specific outcome is the progression of a trigeminal ganglion over time, from its formation to the mature structure.


go_id: GO:0061553
term: ganglion maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for ganglion to attain its fully functional state.


go_id: GO:0061554
term: ganglion formation
ontology: BP
definition:
The process that gives rise to ganglion. This process pertains to the initial formation of a structure from unspecified parts.


go_id: GO:0061555
term: ganglion structural organization
ontology: BP
definition:
The process that contributes to creating the structural organization of a ganglion. This process pertains to the physical shaping of a rudimentary structure.


go_id: GO:0061557
term: trigeminal ganglion maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for a trigeminal ganglion to attain its fully functional state.


go_id: GO:0061558
term: cranial ganglion maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for a cranial ganglion to attain its fully functional state.


go_id: GO:0061560
term: cranial ganglion formation
ontology: BP
definition:
The process that gives rise to a cranial ganglion. This process pertains to the initial formation of a structure from unspecified parts.


go_id: GO:0061561
term: trigeminal ganglion formation
ontology: BP
definition:
The process that gives rise to the trigeminal ganglion. This process pertains to the initial formation of a structure from unspecified parts.


go_id: GO:0061562
term: cranial ganglion structural organization
ontology: BP
definition:
The process that contributes to creating the structural organization of a cranial ganglion. This process pertains to the physical shaping of a rudimentary structure.


go_id: GO:0061563
term: trigeminal ganglion structural organization
ontology: BP
definition:
The process that contributes to creating the structural organization of the trigeminal ganglion This process pertains to the physical shaping of a rudimentary structure.


go_id: GO:0061564
term: axon development
ontology: BP
definition:
The progression of an axon over time. Covers axonogenesis (de novo generation of an axon) and axon regeneration (regrowth), as well as processes pertaining to the progression of the axon over time (fasciculation and defasciculation).


go_id: GO:0061565
term: dAMP phosphorylation
ontology: BP
definition:
The process of introducing a phosphate group into dAMP, deoxyadenosine monophosphate, to produce dADP. Addition of two phosphate groups produces dATP.


go_id: GO:0061566
term: CMP phosphorylation
ontology: BP
definition:
The process of introducing a phosphate group into CMP, cytidine monophosphate, to produce CDP. Addition of two phosphate groups produces CTP.


go_id: GO:0061567
term: dCMP phosphorylation
ontology: BP
definition:
The process of introducing a phosphate group into dCMP, deoxycytidine monophosphate, to produce dCDP. Addition of two phosphate groups produces dCTP.


go_id: GO:0061572
term: actin filament bundle organization
ontology: BP
definition:
A process that results in the assembly, arrangement of constituent parts, or disassembly of an actin filament bundle.


go_id: GO:0061573
term: actin filament bundle retrograde transport
ontology: BP
definition:
A process of actin filament bundle distribution that results in the arrangement of actin filament bundles from the periphery toward the interior of the cell.


go_id: GO:0061574
term: ASAP complex
ontology: CC
definition:
A protein complex involved in regulation of mRNA processing and apoptosis. It binds to RNA in a sequence-independent manner and is recruited to the EJC prior to or during the splicing process. In humans the core proteins are RNPS1, SAP18 and ACIN1.


go_id: GO:0061576
term: acyl-CoA ceramide synthase complex
ontology: CC
definition:
A protein complex that catalyzes the reaction acyl-CoA + sphingosine = CoA + N-acylsphingosine. In S. cerevisiae it contains three subunits: lag1, lac1 and lip1.


go_id: GO:0061577
term: calcium ion transmembrane transport via high voltage-gated calcium channel
ontology: BP
definition:
A process in which a calcium ion is transported from one side of a membrane to the other by means of a high voltage-gated calcium channel.


go_id: GO:0061579
term: N-acyl homoserine lactone synthase activity
ontology: MF
definition:
Catalyzing the reaction: acyl-[acyl-carrier-protein] + S-adenosyl-L-methionine -> [acyl-carrier- protein] + S-methyl-5'-thioadenosine + N-acyl-L-homoserine lactone.


go_id: GO:0061580
term: colon epithelial cell migration
ontology: BP
definition:
The orderly movement of a colonic epithelial cell from one site to another, often during the development of a multicellular organism.


go_id: GO:0061581
term: corneal epithelial cell migration
ontology: BP
definition:
The orderly movement of a corneal  epithelial cell from one site to another, often during the development of a multicellular organism.


go_id: GO:0061582
term: intestinal epithelial cell migration
ontology: BP
definition:
The orderly movement of an intestinal epithelial cell from one site to another, often during the development of a multicellular organism.


go_id: GO:0061583
term: colon epithelial cell chemotaxis
ontology: BP
definition:
The directed movement of a colon epithelial cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).


go_id: GO:0061586
term: positive regulation of transcription by transcription factor localization
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the localization of a transcription factor.


go_id: GO:0061587
term: transfer RNA gene-mediated silencing
ontology: BP
definition:
The chromatin silencing that results in the inhibition of RNA polymerase II-transcribed genes located in the vicinity of tRNA genes.


go_id: GO:0061588
term: calcium activated phospholipid scrambling
ontology: BP
definition:
The movement of a population of phospholipid molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus.


go_id: GO:0061589
term: calcium activated phosphatidylserine scrambling
ontology: BP
definition:
The movement of a population of phosphatidylserine molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus.


go_id: GO:0061590
term: calcium activated phosphatidylcholine scrambling
ontology: BP
definition:
The movement of a population of phosphatidylcholine molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus.


go_id: GO:0061591
term: calcium activated galactosylceramide scrambling
ontology: BP
definition:
The movement of a population of galactosylceramide molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus.


go_id: GO:0061592
term: phosphatidylserine exposure on osteoblast involved in bone mineralization
ontology: BP
definition:
A phospholipid scrambling process that results in the appearance of phosphatidylserine on the surface of osteoblasts, and contributes to bone mineralization.


go_id: GO:0061594
term: 6-deoxy-6-sulfofructose kinase activity
ontology: MF
definition:
Catalysis of the reaction 6-deoxy-6-sulfofructose + ATP = 6-deoxy-6-sulfofructose-1-phosphate + ADP.


go_id: GO:0061595
term: 6-deoxy-6-sulfofructose-1-phosphate aldolase activity
ontology: MF
definition:
Catalysis of the reaction 6-deoxy-6-sulfofructose-1-phosphate = 3-sulfolactaldehyde + dihydroxyacetone phosphate.


go_id: GO:0061596
term: 3-sulfolactaldehyde reductase activity
ontology: MF
definition:
Catalysis of the reaction 2,3-dihydroxypropane-1-sulfonate + NAD+ = 3-sulfolactaldehyde + NADH + H+.


go_id: GO:0061604
term: molybdopterin-synthase sulfurtransferase activity
ontology: MF
definition:
Catalysis of the reaction: [Molybdopterin-synthase sulfur-carrier protein]-Gly-Gly-AMP + [cysteine desulfurase]-S-sulfanyl-L-cysteine <=> AMP [molybdopterin-synthase sulfur-carrier protein]-Gly-NH-CH(2)-C(O)SH + cysteine desulfurase.


go_id: GO:0061605
term: molybdopterin-synthase adenylyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: ATP [molybdopterin-synthase sulfur-carrier protein]-Gly-Gly = diphosphate [molybdopterin-synthase sulfur-carrier protein]-Gly-Gly-AMP.


go_id: GO:0061607
term: peptide alpha-N-propionyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: propionyl-CoA + peptide = CoA + N-alpha-propionylpeptide. This reaction is the propionylation of the N-terminal amino acid residue of a peptide or protein.


go_id: GO:0061608
term: nuclear import signal receptor activity
ontology: MF
definition:
Combining with a nuclear import signal (NIS) on a cargo to be transported, to mediate transport of the cargo through the nuclear pore, from the cytoplasm to the nuclear lumen. The cargo can be either a RNA or a protein.


go_id: GO:0061610
term: glycerol to glycerone phosphate metabolic process
ontology: BP
definition:
The chemical reactions and pathways in which glycerol, 1,2,3-propanetriol, is converted to glycerone phosphate.


go_id: GO:0061611
term: mannose to fructose-6-phosphate metabolic process
ontology: BP
definition:
The chemical reactions and pathways in which mannose, the aldohexose manno-hexose, is converted to fructose-6-phosphate.


go_id: GO:0061612
term: galactose to glucose-1-phosphate metabolic process
ontology: BP
definition:
The chemical reactions and pathways in which galactose, the aldohexose galacto-hexose, is converted to glucose-1-phosphate.


go_id: GO:0061614
term: miRNA transcription
ontology: BP
definition:
The cellular synthesis of microRNA (miRNA) transcripts. MicroRNA genes are synthesized as primary (pri) miRNA transcripts and subsequently processed to produce the ~22nt miRNAs that function in gene regulation.


go_id: GO:0061615
term: glycolytic process through fructose-6-phosphate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of a monosaccharide into pyruvate, occurring through a fructose-6-phosphate intermediate, with the concomitant production of ATP and NADH.


go_id: GO:0061617
term: MICOS complex
ontology: CC
definition:
Mitochondrial inner membrane complex involved in maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. In Saccharomyces cerevisiae the complex has six subunits: MIC10, MIC12, MIC19, MIC26, MIC27, and MIC60.


go_id: GO:0061619
term: glycolytic process from mannose through fructose-6-phosphate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of mannose into pyruvate, occurring through a fructose-6-phosphate intermediate, with the concomitant production of ATP and NADH.


go_id: GO:0061620
term: glycolytic process through glucose-6-phosphate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, occurring through a glucose-6-phosphate intermediate, with the concomitant production of a small amount of ATP.


go_id: GO:0061621
term: canonical glycolysis
ontology: BP
definition:
The glycolytic process that begins with the conversion of glucose to glucose-6-phosphate by glucokinase activity. Glycolytic processes are the  chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP.


go_id: GO:0061622
term: glycolytic process through glucose-1-phosphate
ontology: BP
definition:
The chemical reactions and pathways through a glucose-1-phosphate intermediate that result in the catabolism of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP.


go_id: GO:0061623
term: glycolytic process from galactose
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of galactose into pyruvate, with the concomitant production of a small amount of ATP.


go_id: GO:0061624
term: fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of fructose that results in the formation of dihydroxyacetone phosphate and glyceraldehyde-3-phosphate.


go_id: GO:0061625
term: glycolytic process through fructose-1-phosphate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of fructose into pyruvate through a fructose-1-phosphate intermediate, with the concomitant production of ATP and NADH.


go_id: GO:0061626
term: pharyngeal arch artery morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of a pharyngeal arch artery is generated and organized. The pharyngeal arch arteries are a series of six paired embryological vascular structures, the development of which give rise to several major arteries, such as the stapedial artery, the middle meningeal artery, the internal carotid artery and the pulmonary artery.


go_id: GO:0061628
term: H3K27me3 modified histone binding
ontology: MF
definition:
Binding to a histone H3 in which the lysine residue at position 27 has been modified by trimethylation.


go_id: GO:0061629
term: RNA polymerase II-specific DNA-binding transcription factor binding
ontology: MF
definition:
Binding to a sequence-specific DNA binding RNA polymerase II transcription factor, any of the factors that interact selectively and non-covalently with a specific DNA sequence in order to modulate transcription.


go_id: GO:0061630
term: ubiquitin protein ligase activity
ontology: MF
definition:
Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues.


go_id: GO:0061631
term: ubiquitin conjugating enzyme activity
ontology: MF
definition:
Isoenergetic transfer of ubiquitin from one protein to another via the reaction X-ubiquitin + Y -> Y-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue.


go_id: GO:0061632
term: RNA lariat debranching enzyme activator activity
ontology: MF
definition:
Increases the activity of an enzyme that catalyzes the hydrolysis of branched RNA structures that contain vicinal 2'-5'- and 3'-5'-phosphodiester bonds at a branch point nucleotide.


go_id: GO:0061633
term: transport-coupled glycolytic process through glucose-6-phosphate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of glucose into pyruvate, in which the glucose is converted to glucose-6-phosphate intermediate coupled to transmembrane transport.


go_id: GO:0061634
term: alpha-D-xyloside xylohydrolase
ontology: MF
definition:
Catalysis of the hydrolysis of terminal, non-reducing alpha-D-xylose residues with release of alpha-D-xylose.


go_id: GO:0061635
term: regulation of protein complex stability
ontology: BP
definition:
Any process that affects the structure and integrity of a protein complex by altering the likelihood of its assembly or disassembly.


go_id: GO:0061638
term: CENP-A containing chromatin
ontology: CC
definition:
The specialized chromatin located in the centromeric core region or the entire centromeric region in organisms with point centromeres, which is enriched for CENP-A-containing nucleosomes. This chromatin forms a 3-dimensional structure which provides a platform for kinetochore assembly and microtubule attachment.


go_id: GO:0061639
term: Cdv-dependent cytokinesis
ontology: BP
definition:
A cytokinesis that involves a set of conserved proteins including the Cdv proteins, and results in the formation of two similarly sized and shaped cells.


go_id: GO:0061640
term: cytoskeleton-dependent cytokinesis
ontology: BP
definition:
A cytokinesis that involves the function of a set of proteins that are part of the microfilament or microtubule cytoskeleton.


go_id: GO:0061642
term: chemoattraction of axon
ontology: BP
definition:
The process in which a neuron growth cone is directed to a specific target site in response to an attractive chemical signal.


go_id: GO:0061643
term: chemorepulsion of axon
ontology: BP
definition:
The process in which a neuron growth cone is directed to a specific target site in response to a repulsive chemical cue.


go_id: GO:0061645
term: endocytic patch
ontology: CC
definition:
The part of the cell cortex consisting of  an aggregation of proteins that will give rise to an endocytic vesicle.


go_id: GO:0061646
term: positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of glutamate secretion in response to membrane depolarization, where glutamate acts as a neurotransmitter.


go_id: GO:0061650
term: ubiquitin-like protein conjugating enzyme activity
ontology: MF
definition:
Isoenergetic transfer of a ubiquitin-like protein (ULP) from one protein to another via the reaction X-SCP + Y -> Y-SCP + X, where both the X-SCP and Y-SCP linkages are thioester bonds between the C-terminal amino acid of SCP and a sulfhydryl side group of a cysteine residue.


go_id: GO:0061651
term: Atg12 conjugating enzyme activity
ontology: MF
definition:
Isoenergetic transfer of Atg12 from one protein to another via the reaction X-Atg12 + Y -> Y-Atg12 + X, where both the X-Atg12 and Y-Atg12 linkages are thioester bonds between the C-terminal amino acid of Atg12 and a sulfhydryl side group of a cysteine residue.


go_id: GO:0061652
term: FAT10 conjugating enzyme activity
ontology: MF
definition:
Isoenergetic transfer of FAT10 from one protein to another via the reaction X-FAT10 + Y -> Y-FAT10 + X, where both the X-FAT10 and Y-FAT10 linkages are thioester bonds between the C-terminal amino acid of FAT10 and a sulfhydryl side group of a cysteine residue.


go_id: GO:0061653
term: ISG15 conjugating enzyme activity
ontology: MF
definition:
Isoenergetic transfer of ISG15 from one protein to another via the reaction X-ISG15 + Y -> Y-ISG15 + X, where both the X-ISG15 and Y-ISG15 linkages are thioester bonds between the C-terminal amino acid of ISG15 and a sulfhydryl side group of a cysteine residue.


go_id: GO:0061654
term: NEDD8 conjugating enzyme activity
ontology: MF
definition:
Isoenergetic transfer of NEDD8 from one protein to another via the reaction X-NEDD8 + Y -> Y-NEDD8 + X, where both the X-NEDD8 and Y-NEDD8 linkages are thioester bonds between the C-terminal amino acid of NEDD8 and a sulfhydryl side group of a cysteine residue.


go_id: GO:0061655
term: Pup conjugating enzyme activity
ontology: MF
definition:
Isoenergetic transfer of Pup from one protein to another via the reaction X-Pup + Y -> Y-Pup + X, where both the X-Pup and Y-Pup linkages are thioester bonds between the C-terminal amino acid of Pup and a sulfhydryl side group of a cysteine residue.


go_id: GO:0061656
term: SUMO conjugating enzyme activity
ontology: MF
definition:
Isoenergetic transfer of SUMO from one protein to another via the reaction X-SUMO + Y -> Y-SUMO + X, where both the X-SUMO and Y-SUMO linkages are thioester bonds between the C-terminal amino acid of SUMO and a sulfhydryl side group of a cysteine residue.


go_id: GO:0061657
term: UFM1 conjugating enzyme activity
ontology: MF
definition:
Isoenergetic transfer of UFM1 from one protein to another via the reaction X-UFM1 + Y -> Y-UFM1 + X, where both the X-UFM1 and Y-UFM1 linkages are thioester bonds between the C-terminal amino acid of UFM1 and a sulfhydryl side group of a cysteine residue.


go_id: GO:0061658
term: URM1 conjugating enzyme activity
ontology: MF
definition:
Isoenergetic transfer of URM1 from one protein to another via the reaction X-URM1 + Y -> Y-URM1 + X, where both the X-URM1 and Y-URM1 linkages are thioester bonds between the C-terminal amino acid of URM1 and a sulfhydryl side group of a cysteine residue.


go_id: GO:0061659
term: ubiquitin-like protein ligase activity
ontology: MF
definition:
Catalysis of the transfer of a ubiquitin-like protein (ULP) to a substrate protein via the reaction X-ULP + S --> X + S-ULP, where X is either an E2 or E3 enzyme, the X-ULP linkage is a thioester bond, and the S-ULP linkage is an isopeptide bond between the C-terminal glycine of ULP and the epsilon-amino group of lysine residues in the substrate.


go_id: GO:0061660
term: Atg12 ligase activity
ontology: MF
definition:
Catalysis of the transfer of Atg12 to a substrate protein via the reaction X-Atg12 + S --> X + S-Atg12, where X is either an E2 or E3 enzyme, the X-Atg12 linkage is a thioester bond, and the S-Atg12 linkage is an isopeptide bond between the C-terminal amino acid of Atg12 and the epsilon-amino group of lysine residues in the substrate.


go_id: GO:0061661
term: FAT10 ligase activity
ontology: MF
definition:
Catalysis of the transfer of FAT10 to a substrate protein via the reaction X-FAT10 + S --> X + S-FAT10, where X is either an E2 or E3 enzyme, the X-FAT10 linkage is a thioester bond, and the S-FAT10 linkage is an isopeptide bond between the C-terminal glycine of FAT10 and the epsilon-amino group of lysine residues in the substrate.


go_id: GO:0061662
term: ISG15 ligase activity
ontology: MF
definition:
Catalysis of the transfer of a ISG15 to a substrate protein via the reaction X-ISG15 + S --> X + S-ISG15, where X is either an E2 or E3 enzyme, the X-ISG15 linkage is a thioester bond, and the S-ISG15 linkage is an isopeptide bond between the C-terminal amino acid of ISG15 and the epsilon-amino group of lysine residues in the substrate.


go_id: GO:0061663
term: NEDD8 ligase activity
ontology: MF
definition:
Catalysis of the transfer of NEDD8 to a substrate protein via the reaction X-NEDD8 + S --> X + S-NEDD8, where X is either an E2 or E3 enzyme, the X-NEDD8 linkage is a thioester bond, and the S-NEDD8 linkage is an isopeptide bond between the C-terminal amino acid of NEDD8 and the epsilon-amino group of lysine residues in the substrate.


go_id: GO:0061664
term: Pup ligase activity
ontology: MF
definition:
Catalysis of the transfer of Pup to a substrate protein via the reaction X-Pup + S --> X + S-Pup, where X is either an E2 or E3 enzyme, the X-Pup linkage is a thioester bond, and the S-Pup linkage is an isopeptide bond between the C-terminal amino acid of Pup and the epsilon-amino group of lysine residues in the substrate.


go_id: GO:0061665
term: SUMO ligase activity
ontology: MF
definition:
Catalysis of the transfer of SUMO to a substrate protein via the reaction X-SUMO + S --> X + S-SUMO, where X is either an E2 or E3 enzyme, the X-SUMO linkage is a thioester bond, and the S-SUMO linkage is an isopeptide bond between the C-terminal amino acid of SUMO and the epsilon-amino group of lysine residues in the substrate.


go_id: GO:0061666
term: UFM1 ligase activity
ontology: MF
definition:
Catalysis of the transfer of UFM1 to a substrate protein via the reaction X-UFM1 + S --> X + S-UFM1, where X is either an E2 or E3 enzyme, the X-UFM1 linkage is a thioester bond, and the S-UFM1 linkage is an isopeptide bond between the C-terminal amino acid of UFM1 and the epsilon-amino group of lysine residues in the substrate.


go_id: GO:0061667
term: URM1 ligase activity
ontology: MF
definition:
Catalysis of the transfer of URM1 to a substrate protein via the reaction X-URM1 + S --> X + S-URM1, where X is either an E2 or E3 enzyme, the X-URM1 linkage is a thioester bond, and the S-URM1 linkage is an isopeptide bond between the C-terminal amino acid of URM1 and the epsilon-amino group of lysine residues in the substrate.


go_id: GO:0061668
term: mitochondrial ribosome assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of the mitochondrial ribosome and of its subunits.


go_id: GO:0061669
term: spontaneous neurotransmitter secretion
ontology: BP
definition:
Neurotransmitter secretion that occurs in the absence of the action of a secretagogue or a presynaptic action potential.


go_id: GO:0061670
term: evoked neurotransmitter secretion
ontology: BP
definition:
Neurotransmitter secretion that occurs in the presence of the action of a secretagogue or a presynaptic action potential.


go_id: GO:0061671
term: Cbp3p-Cbp6 complex
ontology: CC
definition:
A protein complex located at the mitochondrial ribosome tunnel exit that is involved in efficient translation and protein complex assembly.


go_id: GO:0061672
term: glutathione hydrolase complex
ontology: CC
definition:
Enzyme complex that in S. cerevisiae has components Dug2/Dug3 and is able to catalyze the cleavage of glutathione into glutamate and Cys-Gly.


go_id: GO:0061673
term: mitotic spindle astral microtubule
ontology: CC
definition:
Any of the mitotic spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell.


go_id: GO:0061674
term: gap filling involved in double-strand break repair via nonhomologous end joining
ontology: BP
definition:
Repair of the gaps in the DNA helix using a discontinuous template during double-strand break repair via nonhomologous end joining.


go_id: GO:0061675
term: RBL family protein binding
ontology: MF
definition:
Binding to a member of the rhamnose-binding lectin (RBL) family, a family of animal lectins that show specific binding activities to L-rhamnose or D-galactose.


go_id: GO:0061678
term: Entner-Doudoroff pathway
ontology: BP
definition:
A cellular carbohydrate catabolic process that converts a carbohydrate to pyruvate and either glyceraldehyde or glyceraldehyde-3 phosphate by dehydration and aldol cleavage via a gluconate or 6-phosphogluconate intermediate.


go_id: GO:0061680
term: Entner-Doudoroff pathway through gluconate to D-glyceraldehyde
ontology: BP
definition:
The Entner-Doudoroff pathway that proceeds through a D-gluconate intermediate and yields pyruvate and D-glyceraldehyde.


go_id: GO:0061681
term: Entner-Doudoroff pathway through gluconate to D-glyceraldehyde-3-phosphate
ontology: BP
definition:
The Entner-Doudoroff pathway that proceeds through a D-gluconate intermediate and yields pyruvate and D-glyceraldehyde-3-phosphate.


go_id: GO:0061683
term: branching involved in seminal vesicle morphogenesis
ontology: BP
definition:
The process in which the branching structure of the seminal vesicle is generated and organized. A branch is a division or offshoot from a main stem.


go_id: GO:0061684
term: chaperone-mediated autophagy
ontology: BP
definition:
The autophagy process which begins when chaperones and co-chaperones recognize a target motif and unfold the substrate protein. The proteins are then transported to the lysosome where they are degraded.


go_id: GO:0061686
term: hercynylcysteine sulfoxide synthase activity
ontology: MF
definition:
Catalysis of the reaction: L-cysteine + N-alpha,N-alpha,N-alpha-trimethyl-L-histidine (hercynine) + O2 <=> hercynylcysteine sulfoxide + H2O.


go_id: GO:0061687
term: detoxification of inorganic compound
ontology: BP
definition:
Any process that reduces or removes the toxicity of inorganic compounds. These include transport of such compounds away from sensitive areas and to compartments or complexes whose purpose is sequestration of inorganic compounds.


go_id: GO:0061688
term: glycolytic process via Entner-Doudoroff Pathway
ontology: BP
definition:
A glycolytic process in which the glucose is catabolized to pyruvate by first entering the Entner-Doudoroff pathway to yield pyruvate and glyceraldehyde-3-phosphate. The glyceraldehyde-3-phosphate is subsequently converted to pyruvate by the core glycolytic enzymes.


go_id: GO:0061689
term: tricellular tight junction
ontology: CC
definition:
An specialized occluding junction where three epithelial cells meet. It is composed of a branching network of sealing strands that run perpendicularly to the bicellular tight junction at the point of contact between three epithelial cells in an epithelial sheet.


go_id: GO:0061691
term: detoxification of hydrogen peroxide
ontology: BP
definition:
Any process that reduces or removes the toxicity of hydrogen peroxide. These include transport of hydrogen peroxide away from sensitive areas and to compartments or complexes whose purpose is sequestration.


go_id: GO:0061692
term: cellular detoxification of hydrogen peroxide
ontology: BP
definition:
Any process that reduces or removes the toxicity of hydrogen peroxide in a cell. These include transport of hydrogen peroxide away from sensitive areas and to compartments or complexes whose purpose is sequestration.


go_id: GO:0061693
term: alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
ontology: MF
definition:
Catalysis of the reaction: ATP + methylphosphonate = alpha-D-ribose 1-methylphosphonate 5-triphosphate + adenine.


go_id: GO:0061694
term: alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase complex
ontology: CC
definition:
A catalytic protein complex that is capable of alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity.


go_id: GO:0061695
term: transferase complex, transferring phosphorus-containing groups
ontology: CC
definition:
A transferase complex capable of catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).


go_id: GO:0061696
term: pituitary gonadotropin complex
ontology: CC
definition:
A protein complex that is a protein hormone secreted by gonadotrope cells of the anterior pituitary of vertebrates. capable of regulating normal growth, sexual development, and reproductive function.


go_id: GO:0061697
term: protein-glutaryllysine deglutarylase activity
ontology: MF
definition:
Catalysis of the reaction: H2O + N(6)-glutaryl-L-lysyl-[protein] + NAD(+) = 2''-O-glutaryl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.


go_id: GO:0061699
term: peptidyl-lysine deglutarylation
ontology: BP
definition:
The removal of a glutaryl group (CO-CH2-CH2--CH2-CO) from a glutarylated lysine residue in a peptide or protein.


go_id: GO:0061700
term: GATOR2 complex
ontology: CC
definition:
A multiprotein subcomplex of the GATOR complex that regulates TORC1 signaling by interacting with the Rag GTPase. In human, this complex consists of WDR24, WDR59, MIOS, SEH1L, and SEC13. In S. cerevisiae, this complex is referred to as SEACAT and contains the Sea2p, Sea3p, Sea4p, Seh1p, Sec13p proteins.


go_id: GO:0061703
term: pyroptosome complex
ontology: CC
definition:
A protein complex that consists of an assemble of ASC dimers that is capable of inducing pyroptosis.


go_id: GO:0061704
term: glycolytic process from sucrose
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of a sucrose into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.


go_id: GO:0061705
term: sucrose catabolic process to fructose-6-phosphate through glucose and fructose
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of sucrose, to yield fructose-6-phosphate through both glucose and fructose intermediates.


go_id: GO:0061706
term: glycolytic process from sucrose through glucose and fructose
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of sucrose into pyruvate through both glucose and fructose intermediates, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.


go_id: GO:0061707
term: extracellular exosome macropinocytosis
ontology: BP
definition:
The single-organism macropinocytosis process that results in the uptake of an extracellular exosome.


go_id: GO:0061708
term: tRNA-5-taurinomethyluridine 2-sulfurtransferase
ontology: MF
definition:
Catalysis of 5-taurinomethyluridine in tRNA + a [protein]-S-sulfanylcysteine + ATP + a reduced electron acceptor = a 5-taurinomethyl-2-thiouridine in tRNA + a [protein]-L-cysteine + AMP + an oxidized electron acceptor + diphosphate + H+.


go_id: GO:0061709
term: reticulophagy
ontology: BP
definition:
The selective autohagy process in which parts of the endoplasmic reticulum are loaded into autophagosomes, delivered to the vacuole, and degraded in response to changing cellular conditions.


go_id: GO:0061710
term: L-threonylcarbamoyladenylate synthase
ontology: MF
definition:
Catalysis of the reaction:  L-threonine + ATP + bicarbonate = L-threonylcarbamoyladenylate + diphosphate + H(2)O.


go_id: GO:0061711
term: N(6)-L-threonylcarbamoyladenine synthase activity
ontology: MF
definition:
Catalysis of the reaction: L-threonylcarbamoyladenylate + adenine(37) in tRNA = AMP + N(6)-L-threonylcarbamoyladenine(37) in tRNA.


go_id: GO:0061712
term: tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
ontology: MF
definition:
Catalysis of the reaction: N(6)-L-threonylcarbamoyladenine(37) in tRNA + sulfur-(sulfur carrier) + 2 S-adenosyl-L-methionine = 2-methylthio-N(6)-L-threonylcarbamoyladenine(37) in tRNA + S-adenosyl-L-homocysteine + (sulfur carrier) + L-methionine + 5'-deoxyadenosine.


go_id: GO:0061713
term: anterior neural tube closure
ontology: BP
definition:
The step in the formation of the neural tube, where the paired anterior neural folds are brought together and fuse at the dorsal midline.


go_id: GO:0061714
term: folic acid receptor activity
ontology: MF
definition:
Combining selectively with extracellular folic acid and delivering it into the cell via endocytosis.


go_id: GO:0061718
term: glucose catabolic process to pyruvate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of glucose, with the production of pyruvate.


go_id: GO:0061719
term: glucose catabolic process to pyruvate utilizing ADP
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of glucose into pyruvate, with the concomitant production of a small amount of ATP and the utilization of ADP in the initial kinase reactions.


go_id: GO:0061720
term: 6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-) resulting in the formation of glycerone phosphate (DHAP) and 3-sulfolactaldehyde (SLA).


go_id: GO:0061721
term: 6-sulfoquinovose(1-) catabolic process to 3-sulfopropanediol(1-)
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-) resulting in the formation of glycerone phosphate (DHAP) and 3-sulfopropanediol(1-).


go_id: GO:0061722
term: sulphoglycolysis
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-) resulting in the formation of glycerone phosphate (DHAP) and pyruvate.


go_id: GO:0061723
term: glycophagy
ontology: BP
definition:
The selective autophagy process in which cellular glycogen is delivered to the vacuole and degraded in response to changing cellular conditions.


go_id: GO:0061724
term: lipophagy
ontology: BP
definition:
The selective autophagy process in which lipid droplets are delivered to the vacuole and degraded in response to changing cellular conditions.


go_id: GO:0061725
term: cytosolic lipolysis
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of lipid droplets and hydrolysis of stored triglycerides occurring through the orchestrated activation of cytosolic lipases.


go_id: GO:0061727
term: methylglyoxal catabolic process to lactate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, into lactate.


go_id: GO:0061729
term: GDP-mannose biosynthetic process from fructose-6-phosphate
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of GDP-mannose from fructose-6-phosphate.


go_id: GO:0061731
term: ribonucleoside-diphosphate reductase activity
ontology: MF
definition:
Catalysis of the formation of 2'-deoxyribonucleoside diphosphate from ribonucleoside diphosphate, using either thioredoxin disulfide or glutaredoxin disulfide as an acceptor.


go_id: GO:0061732
term: mitochondrial acetyl-CoA biosynthetic process from pyruvate
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate in the mitochondrion. The process begins with the transport of pyruvate from the cytosol to the mitochondrion where it is subsequently decarboxylated to form acetyl-CoA.


go_id: GO:0061734
term: parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
ontology: BP
definition:
A positive regulation of the macromitophagy pathway that is triggered by mitochondrial depolarization and requires the function of a parkin-family molecule.


go_id: GO:0061735
term: DNM1L-mediated stimulation of mitophagy in response to mitochondrial depolarization
ontology: BP
definition:
A positive regulation of the macromitophagy pathway that is triggered by mitochondrial depolarization and requires the function of a DNM1L-family molecule.


go_id: GO:0061736
term: engulfment of target by autophagosome
ontology: BP
definition:
The membrane invagination process by which an autophagosomal membrane surrounds an object that will be degraded by macroautophagy.


go_id: GO:0061737
term: leukotriene signaling pathway
ontology: BP
definition:
A G protein-coupled receptor signaling pathway initiated by leukotriene binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.


go_id: GO:0061738
term: late endosomal microautophagy
ontology: BP
definition:
The autophagy process by which cytosolic proteins targeted for degradation are tagged with a chaperone and are directly transferred into and degraded in a late endosomal compartment.


go_id: GO:0061739
term: protein lipidation involved in autophagosome assembly
ontology: BP
definition:
The protein lipidation process by which phosphatidylethanolamine is conjugated to a protein of the ATG8 family, leading to membrane insertion of the protein as a step in autophagosome assembly.


go_id: GO:0061740
term: protein targeting to lysosome involved in chaperone-mediated autophagy
ontology: BP
definition:
The targeting of a protein to the lysosome process in which an input protein binds to a chaperone and subsequently to a lysosomal receptor.


go_id: GO:0061742
term: chaperone-mediated autophagy translocation complex
ontology: CC
definition:
A lysosomal membrane protein complex that enables the translocation of a target protein across the lysosomal membrane as part of chaperone-mediated autophagy.


go_id: GO:0061743
term: motor learning
ontology: BP
definition:
Any process in which an organism acquires a novel neuromuscular action or movement as the result of experience.


go_id: GO:0061744
term: motor behavior
ontology: BP
definition:
The specific neuromuscular movement of a single organism in response to external or internal stimuli.


go_id: GO:0061750
term: acid sphingomyelin phosphodiesterase activity
ontology: MF
definition:
Catalysis of the reaction: H(2)O + sphingomyelin = ceramide + choline phosphate + H(+) in an acidic environment.


go_id: GO:0061751
term: neutral sphingomyelin phosphodiesterase activity
ontology: MF
definition:
Catalysis of the reaction: H(2)O + sphingomyelin = ceramide + choline phosphate + H(+) in a neutral environment.


go_id: GO:0061752
term: telomeric repeat-containing RNA binding
ontology: MF
definition:
Binding to long non-coding RNA molecules transcribed from subtelomeric regions in most eukaryotes. Telomeric repeat-containing RNA (TERRA) molecules consist of subtelomeric-derived sequences and G-rich telomeric repeats.


go_id: GO:0061760
term: antifungal innate immune response
ontology: BP
definition:
An defense response against a fungus mediated through an innate immune response. An innate immune response is mediated by germline encoded components that directly recognize components of potential pathogens.


go_id: GO:0061762
term: CAMKK-AMPK signaling cascade
ontology: BP
definition:
The series of molecular signals in which calmodulin-dependent protein kinase activity enabled by a CAMKK directly activates an AMPK. The cascade begins with calmodulin binding calcium which in turn binds CAMKK enabling its calmodulin-dependent protein kinase activity. The cascade ends with AMP-activated protein kinase activity.


go_id: GO:0061763
term: multivesicular body-lysosome fusion
ontology: BP
definition:
The organelle membrane fusion process in which the membrane of a multivesicular body fuses with a lysosome to create a hybrid organelle.


go_id: GO:0061764
term: late endosome to lysosome transport via multivesicular body sorting pathway
ontology: BP
definition:
The directed movement of substances from late endosomes to lysosomes by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the lysosome.


go_id: GO:0061765
term: modulation by virus of host NIK/NF-kappaB cascade
ontology: BP
definition:
Any process in which a virus effect a change in the frequency, rate or extent of NIK/NF-kappaB signaling in the host.


go_id: GO:0061770
term: translation elongation factor binding
ontology: MF
definition:
Binding to a translation elongation factor, any polypeptide factor involved in the peptide elongation in ribosome-mediated translation.


go_id: GO:0061771
term: response to caloric restriction
ontology: BP
definition:
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caloric restriction, insufficient food energy intake.


go_id: GO:0061773
term: eNoSc complex
ontology: CC
definition:
A chromatin silencing complex that recruits histone-modifying enzymes and upregulates silencing of rDNA in response to glucose starvation.


go_id: GO:0061774
term: cohesin unloading
ontology: BP
definition:
Negative regulation of sister chromatid cohesion by the topological unlinking of a cohesin ring to DNA.


go_id: GO:0061775
term: cohesin loading activity
ontology: MF
definition:
Facilitating a conformational change to load a cohesin complex around sister chromatids, driven by ATP hydrolysis.


go_id: GO:0061776
term: topological DNA co-entrapment activity
ontology: MF
definition:
A DNA binding activity in which a protein complex interacts with more than one DNA duplex to encircle the DNA molecules with a loose fitting ring.


go_id: GO:0061778
term: intracellular chloride channel activity
ontology: MF
definition:
Enables the transmembrane transfer of chloride across the membrane of an intracellular compartment. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism.


go_id: GO:0061779
term: Tapasin-ERp57 complex
ontology: CC
definition:
Subunit of the MHC class I peptide loading complex (GO:0042824) (=PLC) involved in the assembly of the heavy-chain-beta2-microglobulin dimers of the MHC class I molecules that fold with eight to ten residue peptides in the endoplasmic reticulum. Required for the inhibition of the reduction of the disulfide bonds of the heavy chains and the assembly and stabilization of the PLC, suggesting it may play a structural rather than a catalytic role.


go_id: GO:0061780
term: mitotic cohesin loading
ontology: BP
definition:
The protein localization to chromatin by which a cohesin ring complex is topologically linked to DNA as part of the mitotic cell cycle.


go_id: GO:0061781
term: mitotic cohesin unloading
ontology: BP
definition:
Negative regulation of sister chromatid cohesion by the topological unlinking of a cohesin ring to DNA as part of the mitotic cell cycle.


go_id: GO:0061784
term: peptidoglycan N-acetylglucosaminidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of (1->4)-beta linkages of N-acetyl-D-glucosamine (GlcNAc) from peptidoglycan.


go_id: GO:0061789
term: dense core granule priming
ontology: BP
definition:
A process that converts unprimed dense core granules (DCVs) to a pool of primed vesicles that are capable of fusing with the plasma membrane (fusion-competent) and thereby releasing their contents. Priming typically occurs after docking.


go_id: GO:0061792
term: secretory granule maturation
ontology: BP
definition:
Steps required to transform an immature secretory vesicle into a mature secretory vesicle. Typically proceeds through homotypic membrane fusion and membrane remodelling.


go_id: GO:0061793
term: chromatin lock complex
ontology: CC
definition:
A chromatin silencing complex that binds and bridges separate nucleosomal histones resulting in heterochromatin assembly and chromatin looping.


go_id: GO:0061794
term: conidium development
ontology: BP
definition:
The process whose specific outcome is the progression of conidium over time, from its formation to the mature structure. Conidia are non-motile spores produced via mitotic asexual reproduction in higher fungi; they are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus.


go_id: GO:0061795
term: Golgi lumen acidification
ontology: BP
definition:
Any process that reduces the pH of the Golgi lumen, measured by the concentration of the hydrogen ion.


go_id: GO:0061796
term: membrane addition at site of mitotic cytokinesis
ontology: BP
definition:
A mitotic cell cycle process involved in the net addition of membrane at the site of cytokinesis; includes vesicle recruitment and fusion, local lipid synthesis and insertion.


go_id: GO:0061797
term: pH-gated chloride channel activity
ontology: MF
definition:
A gated channel activity that enables the transmembrane transfer of a chloride ion by a channel that opens in response to a change in pH.


go_id: GO:0061799
term: cyclic pyranopterin monophosphate synthase activity
ontology: MF
definition:
Catalysis of the reaction:  (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate = cyclic pyranopterin phosphate + diphosphate.


go_id: GO:0061800
term: fibronectin fibril
ontology: CC
definition:
A supramolecular fiber formed from fibronectin molecules. The fibrils are 5 to 25nm in diameter and can form branched meshworks.


go_id: GO:0061802
term: anterior cell cortex
ontology: CC
definition:
The region that lies just beneath the plasma membrane in the part of a cell that is closest to the anterior as defined by the developing, or existing, anterior/posterior axis.


go_id: GO:0061803
term: posterior cell cortex
ontology: CC
definition:
The region that lies just beneath the plasma membrane in the part of a cell that is closest to the posterior as defined by the developing, or existing, anterior/posterior axis.


go_id: GO:0061804
term: mitotic spindle formation (spindle phase one)
ontology: BP
definition:
The cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase.


go_id: GO:0061805
term: mitotic spindle elongation (spindle phase three)
ontology: BP
definition:
The cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic anaphase B.


go_id: GO:0061806
term: regulation of DNA recombination at centromere
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of DNA recombination within centromeric DNA.


go_id: GO:0061807
term: positive regulation of DNA recombination at centromere
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of DNA recombination at the centromere.


go_id: GO:0061808
term: negative regulation of DNA recombination at centromere
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of genetic recombination at the centromere.


go_id: GO:0061809
term: NAD+ nucleotidase, cyclic ADP-ribose generating
ontology: MF
definition:
Catalysis of the reaction: NAD+ + H2O = nicotinamide + ADP-ribose that proceeds in a stepwise fashion by ADP-ribosyl cyclase activity followed by cyclic ADP-ribose hydrolase activity.


go_id: GO:0061810
term: NAD glycohydrolase activity
ontology: MF
definition:
Catalysis of the reaction: NAD+ + H2O = nicotinamide + ADP-ribose without proceeding through a cyclic ADP-ribose intermediate.


go_id: GO:0061816
term: proteaphagy
ontology: BP
definition:
The selective autophagy process that clears 26S proteasomes; homeostatic mechanism within the ubiquitin system that modulates proteolytic capacity and eliminates damaged particles.


go_id: GO:0061819
term: telomeric DNA-containing double minutes formation
ontology: BP
definition:
A telomere maintenance process that results in the formation of small fragments of circular extrachromosomal DNA elements which contain telomeric DNA. It is speculated that telomeric DNA-containing double minutes are formed through a recombination event between the telomere and chromosome-internal TTAGGG-like sequences. Telomeric DNA-containing double minutes appear as two closely positioned dots in metaphase.


go_id: GO:0061820
term: telomeric D-loop disassembly
ontology: BP
definition:
A telomere loop disassembly process that results in the disassembly of telomeric D-loops. A telomeric D-loop is a three-stranded DNA displacement loop that forms at the site where the telomeric 3' single-stranded DNA overhang (formed of the repeat sequence TTAGGG in mammals) is tucked back inside the double-stranded component of telomeric DNA molecule, thus forming a t-loop or telomeric-loop and protecting the chromosome terminus.


go_id: GO:0061821
term: telomeric D-loop binding
ontology: MF
definition:
Binding to a telomeric D-loop. A telomeric D-loop is a three-stranded DNA displacement loop that forms at the site where the telomeric 3' single-stranded DNA overhang (formed of the repeat sequence TTAGGG in mammals) is tucked back inside the double-stranded component of telomeric DNA molecule, thus forming a t-loop or telomeric-loop and protecting the chromosome terminus.


go_id: GO:0061822
term: ciliary cap
ontology: CC
definition:
An intracellular compartmentalized cilium structure found in insect spermatids which is bounded by a membrane derived from the invagination of the cell membrane that remains associated with the primary cilium as it is internalized. The ciliary cap is maintained at the end of the axoneme distal to the centriole and is separated from the cytosolic axoneme/cytoplasm by a putative transition zone, which may extend into the ciliary cap, and include a structure at the base of the ciliary cap termed the ring centriole.


go_id: GO:0061823
term: ring centriole
ontology: CC
definition:
A ring-like structure observed at the base of the ciliary cap of insect spermatids. This structure may anchor the axoneme to the ciliary cap membrane and/or act as a diffusion barrier, proposed to be analogous to the annulus of mammalian sperm flagellum.


go_id: GO:0061824
term: cytosolic ciliogenesis
ontology: BP
definition:
The process in which an axoneme is exposed entirely or partially to the cytoplasm or by which the cytoplasmic portion is assembled or extended. Cytosolic ciliogenesis can occur following compartmentalized ciliogenesis, in which the cilium is formed within a compartment separated from the cytoplasm.


go_id: GO:0061825
term: podosome core
ontology: CC
definition:
The F-actin-rich core of an adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell.


go_id: GO:0061828
term: apical tubulobulbar complex
ontology: CC
definition:
Actin-based structures involved in establishing close contact between mature spermatids and Sertoli cells at the luminal end of the Sertoli cell.


go_id: GO:0061830
term: concave side of sperm head
ontology: CC
definition:
The concave part of the late spermatid head or spermatozoon head that forms the ventral portion of the head, particularly in some rodent species.


go_id: GO:0061831
term: apical ectoplasmic specialization
ontology: CC
definition:
Testis-specific junction between mature spermatids and Sertoli cells at the luminal end of the Sertoli cell.


go_id: GO:0061832
term: basal ectoplasmic specialization
ontology: CC
definition:
Testis-specific junction between mature Sertoli cells involved in establishing the blood-testis barrier of the Sertoli cell.


go_id: GO:0061833
term: protein localization to tricellular tight junction
ontology: BP
definition:
A process in which a protein is transported to, or maintained in, a location within a tricellular tight junction.


go_id: GO:0061836
term: intranuclear rod
ontology: CC
definition:
A macromolecular fiber consisting of actin and cofilin that is formed in the nucleus as a consequence of chemical or mechanical stress conditions.


go_id: GO:0061837
term: neuropeptide processing
ontology: BP
definition:
Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a neuropeptide precursor. Processing leads to the attainment of the full functional capacity of the neuropeptide.


go_id: GO:0061838
term: CENP-T-W-S-X complex
ontology: CC
definition:
A histone-variant containing protein complex which forms a centromere specific nucleosomal structure, involved in centromeric chromatin organization.


go_id: GO:0061840
term: high-affinity ferrous iron transmembrane transporter activity
ontology: MF
definition:
Enables the transfer of ferrous iron (Fe(II) or Fe2+) ions from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.


go_id: GO:0061841
term: high-affinity iron exporter complex
ontology: CC
definition:
A protein complex which transports ferrous iron (Fe(III) or Fe3+) ions from the vacuole, the main storage component of intracellular free iron, into the cytoplasm in a low iron environment.


go_id: GO:0061842
term: microtubule organizing center localization
ontology: BP
definition:
Any process in which the microtubule organizing center is transported to, and/or maintained in, a specific location within the cell.


go_id: GO:0061843
term: Sertoli cell barrier remodeling
ontology: BP
definition:
The tissue remodeling process by which the Sertoli cell barrier is temporarily disrupted and reorganized to accommodate the transit of preleptotene spermatocytes at stage VIII of the epithelial cycle.


go_id: GO:0061847
term: response to cholecystokinin
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholecystokinin stimulus.


go_id: GO:0061848
term: cellular response to cholecystokinin
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholecystokinin stimulus.


go_id: GO:0061849
term: telomeric G-quadruplex DNA binding
ontology: MF
definition:
Binding to telomeric G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures in telomeres.


go_id: GO:0061852
term: retrograte transporter complex, Golgi to ER
ontology: CC
definition:
Transporter complex that recognises, binds and returns endoplasmic reticulum (ER) resident proteins that have trafficked to Golgi compartments. Targets proteins lacking the HDEL motif recognised by COPI-coated vesicles.


go_id: GO:0061856
term: Golgi calcium ion transmembrane transport
ontology: BP
definition:
A process in which a calcium ion is transported from one side of a Golgi membrane to the other by means of some agent such as a transporter or pore.


go_id: GO:0061857
term: endoplasmic reticulum stress-induced pre-emptive quality control
ontology: BP
definition:
The response to endoplasimic reticulum stress in which nascent proteins are degraded by attenuation of their translocation into the ER followed by rerouting to the cytosol without cleavage of the signal peptide, and subsequent degradation by the proteasome.


go_id: GO:0061860
term: DNA clamp unloader activity
ontology: MF
definition:
Facilitating the opening of the ring structure of the PCNA complex, or any of the related sliding clamp complexes, and their removal from the DNA duplex, driven by ATP hydrolysis.


go_id: GO:0061862
term: cellular response to differentiation-inducing factor 2
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one stimulus.


go_id: GO:0061863
term: microtubule plus end polymerase
ontology: MF
definition:
Catalysis of the transfer of tubulin dimers to the plus end of a microtubule. The reaction is reversable depending on the availability of dimers.


go_id: GO:0061864
term: basement membrane constituent secretion
ontology: BP
definition:
The controlled release of molecules that form the basement membrane, including carbohydrates and glycoproteins by a cell.


go_id: GO:0061865
term: polarized secretion of basement membrane proteins in epithelium
ontology: BP
definition:
The basement membrane constituent secretion in which there is a restriction or targeting of basement membrane proteins for controlled release on the basal side of polarized epithelium.


go_id: GO:0061867
term: establishment of mitotic spindle asymmetry
ontology: BP
definition:
The mitotic spindle organization process by which a mitotic spindle becomes asymmetric either in position or structure.


go_id: GO:0061871
term: negative regulation of hepatic stellate cell migration
ontology: BP
definition:
Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell migration.


go_id: GO:0061872
term: hepatic stellate cell contraction
ontology: BP
definition:
The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of a hepatic stellate cell.


go_id: GO:0061874
term: positive regulation of hepatic stellate cell contraction
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of hepatic stellate cell contraction.


go_id: GO:0061875
term: negative regulation of hepatic stellate cell contraction
ontology: BP
definition:
Any process that modulates stops, prevents, or reduces the frequency, rate or extent of hepatic stellate cell contraction.


go_id: GO:0061880
term: regulation of anterograde axonal transport of mitochondrion
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse.


go_id: GO:0061881
term: positive regulation of anterograde axonal transport of mitochondrion
ontology: BP
definition:
Any process that activates or increasesthe frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse.


go_id: GO:0061882
term: negative regulation of anterograde axonal transport of mitochondrion
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse.


go_id: GO:0061883
term: clathrin-dependent endocytosis involved in vitellogenesis
ontology: BP
definition:
A clathrin-mediated endocytosis process whereby yolk proteins are internalized and trafficked through the endocytic pathway for yolk deposition.


go_id: GO:0061884
term: regulation of mini excitatory postsynaptic potential
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of mini excitatory postsynaptic potential. Mini excitatory postsynaptic potential is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse.


go_id: GO:0061885
term: positive regulation of mini excitatory postsynaptic potential
ontology: BP
definition:
Any process that increases the frequency, rate or extent of mini excitatory postsynaptic potential. Mini excitatory postsynaptic potential is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse.


go_id: GO:0061886
term: negative regulation of mini excitatory postsynaptic potential
ontology: BP
definition:
Any process that decreases the frequency, rate or extent of mini excitatory postsynaptic potential. Mini excitatory postsynaptic potential is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse.


go_id: GO:0061891
term: calcium ion sensor activity
ontology: MF
definition:
Binding to and responding, e.g. by conformational change, to changes in the cellular level of calcium ions (Ca2+).


go_id: GO:0061896
term: all-trans retinol 3,4-desaturase activity
ontology: MF
definition:
Catalysis of the reaction: all-trans-retinol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = all-trans-3,4-didehydro retinol + 2 H2O + 2 oxidized [adrenodoxin].


go_id: GO:0061897
term: all-trans retinal 3,4-desaturase activity
ontology: MF
definition:
Catalysis of the reaction: all-trans-retinal + 2 H(+) + O2 + 2 reduced [adrenodoxin] = all-trans-3,4-didehydro retinal + 2 H2O + 2 oxidized [adrenodoxin].


go_id: GO:0061898
term: all-trans retinoic acid 3,4-desaturase activity
ontology: MF
definition:
Catalysis of the reaction: all-trans-retinoic acid + 2 H(+) + O2 + 2 reduced [adrenodoxin] = all-trans-3,4-didehydro retinoic acid + 2 H2O + 2 oxidized [adrenodoxin].


go_id: GO:0061899
term: 11-cis-retinal 3,4-desaturase activity
ontology: MF
definition:
Catalysis of the reaction: 11-cis-retinal + 2 H(+) + O2 + 2 reduced [adrenodoxin] = 11-cis-3,4-didehydro-retinal + 2 H2O + 2 oxidized [adrenodoxin].


go_id: GO:0061900
term: glial cell activation
ontology: BP
definition:
A change in morphology and behavior of a glial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.


go_id: GO:0061901
term: regulation of 1-phosphatidylinositol-3-kinase activity
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of 1-phosphatidylinositol-3-kinase activity.


go_id: GO:0061902
term: negative regulation of 1-phosphatidylinositol-3-kinase activity
ontology: BP
definition:
Any process that stops, prevents or reduces the frequency, rate or extent of 1-phosphatidylinositol-3-kinase activity.


go_id: GO:0061903
term: positive regulation of 1-phosphatidylinositol-3-kinase activity
ontology: BP
definition:
Any process that starts or increases the frequency or rate of 1-phosphatidylinositol-3-kinase activity.


go_id: GO:0061906
term: autophagosome localization
ontology: BP
definition:
Any process in which an autophagosome is transported to, and/or maintained in, a specific location within the cell.


go_id: GO:0061907
term: negative regulation of AMPA receptor activity
ontology: BP
definition:
Any process that stops, prevents or reduces the frequency, rate or extent of AMPA glutamate receptor activity.


go_id: GO:0061908
term: phagophore
ontology: CC
definition:
A disk-like structure that expands, rounds up into a cup-shaped structure, and eventually closes around its cargo (for example cytoplasmic components) to become an autophagosome or Cvt vesicle.


go_id: GO:0061909
term: autophagosome-lysosome fusion
ontology: BP
definition:
The process in which autophagosomes, double-membraned vesicles containing cytoplasmic material, fuse with a vacuole (yeast) or lysosome (e.g. mammals and insects). In the case of yeast, inner membrane-bounded structures (autophagic bodies) appear in the vacuole. Fusion provides an acidic environment and digestive function to the interior of the autophagosome.


go_id: GO:0061910
term: autophagosome-endosome fusion
ontology: BP
definition:
The process in which an autophagosome fuses with an endosome to create an intermediate autophagic organelle called amphisome.


go_id: GO:0061911
term: amphisome-lysosome fusion
ontology: BP
definition:
The process in which amphisomes fuse with a vacuole (yeast) or lysosome (e.g. mammals and insects). In the case of yeast, inner membrane-bounded structures (autophagic bodies) appear in the vacuole. Fusion provides an acidic environment and digestive function to the interior of the amphisome.


go_id: GO:0061913
term: positive regulation of growth plate cartilage chondrocyte proliferation
ontology: BP
definition:
Any process that increases the rate, frequency, or extent of the multiplication or reproduction of chondrocytes in a growing endochondral bone, resulting in the expansion of a cell population.


go_id: GO:0061914
term: negative regulation of growth plate cartilage chondrocyte proliferation
ontology: BP
definition:
Any process that decreases the rate, frequency, or extent of the multiplication or reproduction of chondrocytes in a growing endochondral bone, resulting in the expansion of a cell population.


go_id: GO:0061915
term: actin fusion focus localization
ontology: BP
definition:
Any process in which an actin fusion focus are transported to, or maintained in, a specific location. The actin fusion focus is an aster-like, F-actin-containing structure at the mating projection tip where the cell wall is degraded during conjugation with cellular fusion.


go_id: GO:0061919
term: process utilizing autophagic mechanism
ontology: BP
definition:
A cellular process involving delivery of a portion of the cytoplasm to lysosomes or to the plant or fungal vacuole that does not involve direct transport through the endocytic or vacuolar protein sorting (Vps) pathways. This process typically leads to degradation of the cargo; however, it can also be used to deliver resident proteins, such as in the cytoplasm-to-vacuole targeting (Cvt) pathway.


go_id: GO:0061923
term: (2S,3R,6S,9S)-(-)-protoillud-7-ene synthase activity
ontology: MF
definition:
Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + (2S,3R,6S,9S)-(-)-protoillud-7-ene.


go_id: GO:0061924
term: regulation of formation of radial glial scaffolds
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the formation of radial glial scaffolds. The scaffolds are used as a substrate for the radial migration of cells.


go_id: GO:0061925
term: negative regulation of formation of radial glial scaffolds
ontology: BP
definition:
Any process that reduces the frequency, rate or extent of the formation of radial glial scaffolds. The scaffolds are used as a substrate for the radial migration of cells.


