# go_term

go_id: GO:0061926
term: positive regulation of formation of radial glial scaffolds
ontology: BP
definition:
Any process that increases the frequency, rate or extent of the formation of radial glial cell scaffolds.


go_id: GO:0061927
term: TOC-TIC supercomplex I
ontology: CC
definition:
The protein transport macromolecular complex of the chloroplast membrane that interacts with the precursor proteins and contains components of both the outer membrane and inner membrane complexes containing at least Toc75, Toc159, Toc34 and Tic110.


go_id: GO:0061935
term: fusion of sperm to egg plasma membrane involved in double fertilization forming two zygotes
ontology: BP
definition:
The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of double fertilization forming two zygotes.


go_id: GO:0061936
ontology: BP
term:
fusion of sperm to egg plasma membrane involved in double fertilization forming a zygote and endosperm

definition:
The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of double fertilization forming a zygote and endosperm.


go_id: GO:0061938
term: protein localization to somatodendritic compartment
ontology: BP
definition:
A process in which a protein is transported to or maintained in a location within the somatodendritic compartment.


go_id: GO:0061939
term: c-di-GMP signaling
ontology: BP
definition:
Any process that mediates the transfer of information from one cell to another using c-di-GMP as the signal.


go_id: GO:0061944
term: negative regulation of protein K48-linked ubiquitination
ontology: BP
definition:
Any process that stops, prevents or reduces the frequency, rate or extent of K48-linked ubiquitination, a protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation.


go_id: GO:0061945
term: regulation of protein K48-linked ubiquitination
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of protein K-48-linked ubiquitination, a protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation.


go_id: GO:0061948
term: premature acrosome loss
ontology: BP
definition:
The discharge, by sperm, of a single, anterior secretory granule before the sperm reaches to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents.


go_id: GO:0061949
term: regulation of premature acrosome loss
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of the discharge, by sperm, of a single, anterior secretory granule before the sperm reaches to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents.


go_id: GO:0061950
term: negative regulation of premature acrosome loss
ontology: BP
definition:
Any process that stops, prevents or reduces the discharge, by sperm, of a single, anterior secretory granule before the sperm reaches to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents.


go_id: GO:0061952
term: midbody abscission
ontology: BP
definition:
The process by which the midbody, the cytoplasmic bridge that connects the two prospective daughter cells, is severed at the end of mitotic cytokinesis, resulting in two separate daughter cells.


go_id: GO:0061953
term: mRNA (adenine-N1-)-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + adenine in mRNA = S-adenosyl-L-homocysteine + N(1)-methyladenine in mRNA.


go_id: GO:0061954
term: positive regulation of actin filament polymerization involved in sperm capacitation
ontology: BP
definition:
Any process that icreases the rate or extent of actin polymerization as part of sperm capacitation. This process prevents a spontaneous acrosome reaction.


go_id: GO:0061955
term: positive regulation of actin filament depolymerization involved in acrosome reaction
ontology: BP
definition:
Any process that increases the rate or exent of actin depolymerization as part of the acrosome reaction. This allows the acrosomal membrane and plasma membrane to fuse.


go_id: GO:0061956
term: penetration of cumulus oophorus
ontology: BP
definition:
The infiltration by sperm of the cumulus oophorus to reach the oocyte. The process involves digestive enzymes from a modified lysosome called the acrosome, situated at the head of the sperm.


go_id: GO:0061957
term: NVT complex
ontology: CC
definition:
A protein complex that is capable of contributing to protein localization by the NVT pathway. In fission yeast, the Nvt complex consists of Ape2, Lap2 and Nbr1.


go_id: GO:0061959
term: response to (R)-carnitine
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an (R)-carnitine stimulus.


go_id: GO:0061963
term: regulation of entry into reproductive diapause
ontology: BP
definition:
Any process that modulates the rate or extent of the dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.


go_id: GO:0061964
term: negative regulation of entry into reproductive diapause
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.


go_id: GO:0061965
term: positive regulation of entry into reproductive diapause
ontology: BP
definition:
Any process that activates or increases the rate or extent of the dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.


go_id: GO:0061966
term: establishment of left/right asymmetry
ontology: BP
definition:
The initial formation of the type asymmetry in an organism's body plan or part of an organism with respect to the left and right halves.


go_id: GO:0061967
term: establishment of left sidedness
ontology: BP
definition:
The initial formation of the type asymmetry in an organism's body plan or part of an organism that established the pattern characteristic to its left side.


go_id: GO:0061968
term: maintenance of left/right asymmetry
ontology: BP
definition:
The organization process that preserves the asymmetry in an organism's body plan or part of an organism with respect to the left and right halves.


go_id: GO:0061969
term: maintenance of left sidedness
ontology: BP
definition:
The organization process that preserves the left sidedness in an organism's body plan or part of an organism with respect to the left and right halves.


go_id: GO:0061970
term: maintenance of right sidedness
ontology: BP
definition:
The organization process that preserves the right sidedness in an organism's body plan or part of an organism with respect to the left and right halves.


go_id: GO:0061971
term: replacement bone morphogenesis
ontology: BP
definition:
The process in which bones are generated and organized as a result of the conversion of another structural tissue into bone.


go_id: GO:0061974
term: perichondral bone morphogenesis
ontology: BP
definition:
The process in which bones are generated and organized as a result of the conversion of initial connective tissue surrounding cartilage into bone.


go_id: GO:0061975
term: articular cartilage development
ontology: BP
definition:
The process whose specific outcome is the progression of articular cartilage over time, from its formation to the mature structure.


go_id: GO:0061976
term: temporomandibular joint articular cartilage development
ontology: BP
definition:
The process whose specific outcome is the progression of temporomandibular joint articular cartilage over time, from its formation to the mature structure.


go_id: GO:0061977
term: hip joint articular cartilage development
ontology: BP
definition:
The process whose specific outcome is the progression of hip joint articular cartilage over time, from its formation to the mature structure.


go_id: GO:0061978
term: mandibular condyle articular cartilage development
ontology: BP
definition:
The process whose specific outcome is the progression of mandibular joint condyle articular cartilage over time, from its formation to the mature structure.


go_id: GO:0061979
term: femoral head articular cartilage development
ontology: BP
definition:
The process whose specific outcome is the progression of femoral head articular cartilage over time, from its formation to the mature structure.


go_id: GO:0061980
term: regulatory RNA binding
ontology: MF
definition:
Binding to a small regulatory RNA, a short RNA (usually 50-200 nt long) that is either independently transcribed or processed from a longer RNA by an RNAse enzyme.


go_id: GO:0061982
term: meiosis I cell cycle process
ontology: BP
definition:
A process that contributes to the first meiotic division. The first meiotic division is the reductive division resulting in the separation of homologous chromosome pairs.


go_id: GO:0061983
term: meiosis II cell cycle process
ontology: BP
definition:
A process that coontributes to the second meiotic division. The second meiotic division separates chromatids resulting in a haploid number of chromosomes.


go_id: GO:0061984
term: catabolite repression
ontology: BP
definition:
A process in which the presence of one nutrient source leads to a decrease in the frequency, rate, or extent of processes involved in the metabolism of other nutrient sources.


go_id: GO:0061985
term: carbon catabolite repression
ontology: BP
definition:
A process in which the presence of one carbon source leads to the modulation of the frequency, rate, or extent of the metabolism of other carbon sources.


go_id: GO:0061987
term: negative regulation of transcription from RNA polymerase II promoter by glucose
ontology: BP
definition:
Any process involving glucose that decreases the frequency, rate or extent or transcription from an RNA polymerase II promoter.


go_id: GO:0061988
term: karyosome formation
ontology: BP
definition:
The chromosome organization process in which meiotic chromosomes in the germ cell nucleus cluster together to form a compact spherical structure called the karyosome.


go_id: GO:0061989
term: sperm karyosome formation
ontology: BP
definition:
The chromosome organization process in which meiotic chromosomes in the spem nucleus cluster together to form a compact spherical structure called the karyosome.


go_id: GO:0061990
term: beta-ketodecanoyl-[acyl-carrier-protein] synthase activity
ontology: MF
definition:
Catalysis of the reaction: octanoyl-CoA + a malonyl-[acyl-carrier protein] = a 3-oxodecanoyl-[acyl-carrier protein] + CoA + CO2.


go_id: GO:0061993
term: calcium:proton antiporter complex
ontology: CC
definition:
A protein complex that enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + H+(out) = Ca2+(out) + H+(in).


go_id: GO:0061995
term: ATP-dependent protein-DNA complex displacement activity
ontology: MF
definition:
An activity that displaces proteins or protein complexes from DNA, sometimes in a 'wire stripping' fashion, driven by ATP hydrolysis.


go_id: GO:0061999
term: regulation of cardiac endothelial to mesenchymal transition
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of cardiac endothelial to mesenchymal transition.


go_id: GO:0062000
term: positive regulation of cardiac endothelial to mesenchymal transition
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of cardiac endothelial to mesenchymal trnasition.


go_id: GO:0062001
term: negative regulation of cardiac endothelial to mesenchymal transition
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac endothelial to mesenchymal transition.


go_id: GO:0062002
term: regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity
ontology: BP
definition:
Any process that modulates the frequency or rate of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity.


go_id: GO:0062003
term: negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity
ontology: BP
definition:
Any process that decreases the frequency or rate of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity.


go_id: GO:0062009
term: secondary palate development
ontology: BP
definition:
The biological process whose specific outcome is the progression of the secondary palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The secondary palate is the part of the palate formed from the fusion of the two palatine shelves, extensions of the maxillary prominences.


go_id: GO:0062010
term: primitive palate development
ontology: BP
definition:
The biological process whose specific outcome is the progression of the primitive palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure.


go_id: GO:0062011
term: mitochondrial respiratory chain complex IV pre-assembly complex
ontology: CC
definition:
A protein complex that contributes to and regulates mitochondrial respiratory chain complex IV (COX) formation. It acts by regulating mitochondrial COX1 translation and by promoting the assembly of COX components.


go_id: GO:0062013
term: positive regulation of small molecule metabolic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of a small molecule metabolic process.


go_id: GO:0062014
term: negative regulation of small molecule metabolic process
ontology: BP
definition:
Any process that stops, prevents or reduces the frequency, rate or extent of a small molecule metabolic process.


go_id: GO:0062021
term: mitotic cohesin dsDNA (leading strand) loading
ontology: BP
definition:
The protein localization to chromatin by which a cohesin ring complex is topologically linked to dsDNA (leading strand) as part of the mitotic cell cycle.


go_id: GO:0062022
term: mitotic cohesin ssDNA (lagging strand) loading
ontology: BP
definition:
The ATP-dependent protein localization to chromatin by which a cohesin ring complex is topologically linked to ssDNA (lagging strand) which is already linked to a dsDNA (leading strand) molecule as part of the mitotic cell cycle.


go_id: GO:0062023
term: collagen-containing extracellular matrix
ontology: CC
definition:
An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells.


go_id: GO:0062025
term: regulation of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
ontology: BP
definition:
Any process that modualtes the rate, frequency or extent of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome.


go_id: GO:0062026
term: negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process
ontology: BP
definition:
Any process that stops or decreases the rate, frequency or extent of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome.


go_id: GO:0062027
term: positive regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process
ontology: BP
definition:
Any process that starts or increases the rate, frequency or extent of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome.


go_id: GO:0062028
term: regulation of stress granule assembly
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of stress granule assembly, the aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule.


go_id: GO:0062029
term: positive regulation of stress granule assembly
ontology: BP
definition:
Any process that starts or increases the rate, frequency or extent of stress-granule assembly, the aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule.


go_id: GO:0062030
term: negative regulation of stress granule assembly
ontology: BP
definition:
Any process that stops or decreases the rate, frequency or extent of stress-granule assembly, the aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule.


go_id: GO:0062031
term: filamentous growth MAPK cascade
ontology: BP
definition:
The MAPK cascade which is activated as a result of partial nutrient deprivation and which results in filamentous growth.


go_id: GO:0062032
term: cichorine biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of cichorine, a secondary metabolite found in some species of fungi.


go_id: GO:0062033
term: positive regulation of mitotic sister chromatid segregation
ontology: BP
definition:
Any process that starts or increases the frequency, rate or extent of sister chromatid segregation during mitosis.


go_id: GO:0062034
term: L-pipecolic acid biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of L-pipecolic acid, a metabolite of lysine.


go_id: GO:0062035
term: sensory perception of cold stimulus
ontology: BP
definition:
The series of events required for an organism to receive a cold temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal.


go_id: GO:0062036
term: sensory perception of hot stimulus
ontology: BP
definition:
The series of events required for an organism to receive a hot temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal.


go_id: GO:0062037
term: D-loop DNA binding
ontology: MF
definition:
Binding to a DNA D-loop. A D-loop is a three-stranded DNA structure formed by the invasion of a single DNA strand that base pairs with one strand of duplex DNA, while the rest of the double-stranded DNA does not unwind.


go_id: GO:0062038
term: positive regulation of pheromone response MAPK cascade
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of a pheromone response MAPK cascade.


go_id: GO:0062039
term: biofilm matrix
ontology: CC
definition:
A structure lying external to microbial cells. A biofilm is an aggregate of surface-associated cells, and the biofilm matrix is the envelope of polymeric substances that surrounds the cells.


go_id: GO:0062040
term: fungal biofilm matrix
ontology: CC
definition:
An extracellular matrix lying external to fungal cells. The fungal biofilm matrix consists of polysaccharides, proteins, lipids, and nucleic acids. Fungal biofilms mediate adherence to host tissues, and provide protection from host immune defenses.


go_id: GO:0062041
term: positive regulation of meiotic sister chromatid arm separation
ontology: BP
definition:
Any process that increases the rate or exent of meiotic sister chromatid arm separation, the cell cycle process in which sister chromatid arms are physically detached from each other during meiosis.


go_id: GO:0062042
term: regulation of cardiac epithelial to mesenchymal transition
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of cardiac epithelial to mesenchymal transition, a transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.


go_id: GO:0062043
term: positive regulation of cardiac epithelial to mesenchymal transition
ontology: BP
definition:
Any process that starts or increases the rate, frequency or extent of cardiac epithelial to mesenchymal transition, a transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.


go_id: GO:0062044
term: negative regulation of cardiac epithelial to mesenchymal transition
ontology: BP
definition:
Any process that stops or decreases the rate, frequency or extent of cardiac epithelial to mesenchymal transition, a transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.


go_id: GO:0062045
term: L-lysine alpha-aminotransferase
ontology: MF
definition:
Catalysis of the reaction: L-lysine + pyruvate= epsilon-amino-alpha-ketocaproic acid (KAC) + alanine.


go_id: GO:0062047
term: pipecolic acid N-hydroxylase
ontology: MF
definition:
Catalysis of the reaction: L-pipecolic acid + NAD(P)H + O2 + H+ = N-hydroxypipecolic acid + NAD(P)+ + H2O.


go_id: GO:0062048
term: lymphotoxin complex
ontology: CC
definition:
A homo- or heterotrimeric protein containing complex consisting of alpha and beta lymphotoxin subunits in different stoichiometric combinations.


go_id: GO:0062049
term: protein phosphatase inhibitor complex
ontology: CC
definition:
A protein-containing complex that inhibits protein phosphatase activity by directly binding to a protein phosphatase.


go_id: GO:0062050
term: GPI-mannose ethanolamine phosphate phosphodiesterase activity
ontology: MF
definition:
A phosphoric diester hydrolase activity that removes the ethanolamine phosphate from mannose 2 of a GPI anchor.


go_id: GO:0062051
term: lipopolysaccharide transport system
ontology: CC
definition:
A protein-containing complex that functions to transport lipopolysaccharide from its site of synthesis at the cytoplasmic membrane across the periplasm to the outer membrane in an ATP-dependent manner.


go_id: GO:0062052
term: starch granule initiation
ontology: BP
definition:
The sequence of events that initiates (or primes) the synthesis of semi-crystalline starch granules within photosynthetic chloroplasts or non-photosynthetic amyloplasts.


go_id: GO:0062054
term: fluoride channel activity
ontology: MF
definition:
Enables the facilitated diffusion of fluoride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.


go_id: GO:0062055
term: photosynthetic state transition
ontology: BP
definition:
A regulation of the phtosynthetic light reaction in which the light harvesting antenna complexes transition between photosystems.


go_id: GO:0062056
term: compound eye pigment cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires the specialized features of a compound eye pigment cell, a cell of the retina containing screening pigments that functions to screen photoreceptors from light leaking from adjacent ommatidia.


go_id: GO:0062057
term: L-aspartate:fumarate antiporter activity
ontology: MF
definition:
Enables the transport of L-aspartate and fumarate across a membrane according to the reaction L-aspartate (out) + fumarate (in) = L-aspartate (in) + fumarate (out).


go_id: GO:0062071
term: Pi Mi complex
ontology: CC
definition:
A transcription factor complex composed of a homeodomain protein and the M-specific peptide Mi that acts at the regulatory region of genes required for the activation of meiosis.


go_id: GO:0062072
term: H3K9me3 modified histone binding
ontology: MF
definition:
Binding to a histone H3 in which the lysine residue at position 9 has been modified by trimethylation.


go_id: GO:0062073
term: histone mRNA stem-loop binding complex
ontology: CC
definition:
A protein-containing complex composed of a stem-loop binding protein (in most species SLBP) and its interacting partner (SLIP1 or MIF4GD in most species) that binds to the histone mRNA (hmRNA) 3-prime-stem-loop structure. Facilitates hmRNA translation initiation and may also be involved in its processing and nuclear export.


go_id: GO:0062075
term: pollen aperture formation
ontology: BP
definition:
The cellular component assembly process of forming pollen apertures, areas where exine is reduced or absent, in the pollen cell wall.


go_id: GO:0062077
term: phenylacetyl-CoA 1,2-epoxidase complex
ontology: CC
definition:
A protein complex capable of catalysing the reaction: phenylacetyl-CoA + H(+) + NADPH + O2 = 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA + H2O + NADP(+).


go_id: GO:0062079
term: ATG2-ATG18 complex
ontology: CC
definition:
A protein complex essential for autophagy during nutrient deprivation, a catabolic process that sequesters undesired cellular material into autophagosomes for delivery to lysosomes for degradation. Contributes to nutrition homeostasis and damage control in eukaryotic cells. Functions at a late step of autophagosome formation for efficient completion of sequestration, probably through facilitating recruitment of ATG8-phosphatidylethanolamine (PE) to the preautophagosomal structure (PAS) and/or its protection from deconjugation by ATG4. Composed of ATG2 and ATG18 in Saccharomyces cerevisiae.


go_id: GO:0062080
term: inhibitory MHC class Ib receptor activity
ontology: MF
definition:
Combining with a MHC class Ib protein complex to mediate signaling that inhibits activation of a lymphocyte.


go_id: GO:0062082
term: HLA-E specific inhibitory MHC class Ib receptor activity
ontology: MF
definition:
Combining with a MHC class Ib molecule of the HLA-A subclass to mediate signaling that inhibits activation of a lymphocyte.


go_id: GO:0062083
term: HLA-G specific inhibitory MHC class Ib receptor activity
ontology: MF
definition:
Combining with a MHC class Ib molecule of the HLA-G subclass to mediate signaling that inhibits activation of a lymphocyte.


go_id: GO:0062084
term: regulation of capsule polysaccharide biosynthetic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides that make up the capsule, a protective structure surrounding some species of bacteria and fungi.


go_id: GO:0062085
term: positive regulation of capsule polysaccharide biosynthetic process
ontology: BP
definition:
Any process that activates, maintains or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides that make up the capsule, a protective structure surrounding some species of bacteria and fungi.


go_id: GO:0062091
term: Ycf2/FtsHi complex
ontology: CC
definition:
A protein complex located in the chloroplast inner membrane and facing the stroma that is associated with the chloroplast inner membrane translocase complex and provides the ATPase motor activity to drive import of proteins into the chloroplast stroma.


go_id: GO:0062092
term: Yae1-Lto1 complex
ontology: CC
definition:
A cytosolic complex that functions as an substrate-specific adaptor, linking the cytosolic iron-sulfur protein assembly (CIA) targeting complex to apo-Rli1p, an ABC protein involved in ribosome recycling, facilitating Fe-S cluster insertion and the maturation of the Rli1p.


go_id: GO:0062094
term: stomach development
ontology: BP
definition:
The process whose specific outcome is the progression of the stomach over time, from its formation to the mature structure. The stomach is an expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ.


go_id: GO:0062095
term: endoplasmic reticulum-peroxisome tethering
ontology: BP
definition:
The attachment of an endoplasmic reticulum membrane to a peroxisome via molecular tethers that physically bridge the two membranes and attach them to each other.


go_id: GO:0062097
term: chemosynthesis
ontology: BP
definition:
The cellular metabolic process in which organic chemical compounds are synthesized from carbon-containing molecules and nutrients using energy obtained from the oxidation of inorganic compounds or methane.


go_id: GO:0062101
term: peptidyl-aspartic acid 3-dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: protein L-aspartate + 2-oxoglutarate + O2 = protein 3-hydroxy-L-aspartate + succinate + CO2.


go_id: GO:0062102
term: female germline stem cell symmetric division
ontology: BP
definition:
Division of a female germline stem cell to produce two germline stem cells of the same type as the parent.


go_id: GO:0062104
term: pumilio-response element binding
ontology: MF
definition:
Binding to a region of RNA containing a Pumilio-response element element. The consensus sequence for the element is UGUAAAUA.


go_id: GO:0062105
term: RNA 2'-O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + RNA = S-adenosyl-L-homocysteine + RNA containing 2'-O-methylribonucleotide.


go_id: GO:0062107
term: regulation of protein localization to non-growing cell tip
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of protein localization to a non-growing cell tip.


go_id: GO:0062108
term: negative regulation of protein localization to non-growing cell tip
ontology: BP
definition:
Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to a non-growing cell tip.


go_id: GO:0062109
term: regulation of DNA recombinase disassembly
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of DNA recombinase disassembly, the disaggregation of a DNA recombinase complex into its constituent components.


go_id: GO:0062110
term: negative regulation of DNA recombinase disassembly
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of DNA recombinase complex disassembly, the disaggregation of a DNA recombinase complex into its constituent components.


go_id: GO:0062119
term: LinE complex
ontology: CC
definition:
A protein complex that associates with chromatin to form linear elements in fission yeast. In S. pombe, the LinE complex contains four main structural components (Rec10, Rec25, Rec27, and Mug20) and other associated proteins.


go_id: GO:0062120
term: LinE complex assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components during meiotic prophase to form a LinE complex, the protein complex that associates with chromatin to form linear elements in fission yeast. In S. pombe, the LinE complex contains four main structural components (Rec10, Rec25, Rec27, and Mug20) and other associated proteins.


go_id: GO:0062121
term: linear element maturation
ontology: BP
definition:
The meiotic cell cycle chromosome organization process in which LinE complexes closely associate with chromatin during meiotic prophase to form mature linear elements.


go_id: GO:0062122
term: histone methyltransferase activity (H3-K37 specific)
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 37) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 37). This reaction is the addition of a methyl group onto lysine at position 37 of the histone H3 protein.


go_id: GO:0062125
term: regulation of mitochondrial gene expression
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of mitochondrial gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA).


go_id: GO:0062126
term: fatty acid primary amide metabolic process
ontology: BP
definition:
The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform primary fatty amides.


go_id: GO:0062128
term: MutSgamma complex
ontology: CC
definition:
A heterodimer involved in the stabilization of DNA recombination intermediates, the promotion of crossover recombination, and the proper assembly of the synaptonemal complex in meiotic prophase nuclei. In yeast the complex consists of two subunits, Msh4 and Msh5.


go_id: GO:0062129
term: chitin-based extracellular matrix
ontology: CC
definition:
Any constituent part of a chitin-based noncellular, hardened, or membranous extracellular matrix secreted from the apical surface of an epithelial sheet.


go_id: GO:0062131
term: 3-butenylglucosinolate 2-hydroxylase activity
ontology: MF
definition:
Catalysis of the reaction: gluconapin + a reduced electron acceptor + O2 = xi-progoitrin + an oxidized electron acceptor + H2O.


go_id: GO:0062133
term: negative regulation of L-glutamine biosynthetic process
ontology: BP
definition:
Any process that stops, prevents or reduces the frequency, rate or extent of L-glutamine biosynthesis.


go_id: GO:0062136
term: low-density lipoprotein receptor complex
ontology: CC
definition:
A plasma membrane protein complex capable of low-density lipoprotein particle receptor activity. It may also bind xenobiotic toxins and deliver them into the cell via endocytosis. While most substrates get degraded via the endosome the receptor is recycled to the plasma membrane. It may also act as a transducer of intracellular signal pathways and often acts in corporation with other cell-surface receptors.


go_id: GO:0062139
term: camera-type eye photoreceptor cell development
ontology: BP
definition:
The process whose specific outcome is the progression of a light-responsive receptor in a camera-type eye over time, from its formation to the mature structure.


go_id: GO:0062140
term: hyphae septin collar
ontology: CC
definition:
A septin collar in pathogenic fungi involved in the constriction of hyphae at the plant plasmodesma enabling penetration of an adjacent cell.


go_id: GO:0062141
term: nuclear exosome targeting complex
ontology: CC
definition:
A protein-containing complex that functions with the RNA exosome and contributes to the degradation of abberant transcripts.


go_id: GO:0062142
term: L-beta-ethynylserine biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of L-beta-ethynylserine. L-beta-ethynylserine is an antibiotic produced by Streptomyces bacteria.


go_id: GO:0062143
term: L-propargylglycine biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of L-propargylglycine (Pra). L-propargylglycine is an antibiotic produced by Streptomyces bacteria.


go_id: GO:0062145
term: L-propargylglycine--L-glutamate ligase activity
ontology: MF
definition:
Catalysis of the reaction: ATP + L-glutamate + L-propargylglycine = ADP + H(+) + L-gamma-glutamyl-L-propargylglycine + phosphate.


go_id: GO:0062146
term: 4-chloro-allylglycine synthase activity
ontology: MF
definition:
Catalysis of the reaction: 4-chloro-L-lysine + AH2 + O2 = A + formaldehyde + H2O + L-2-amino-4-chloropent-4-enoate + NH4(+).


go_id: GO:0062147
term: L-lysine 4-chlorinase activity
ontology: MF
definition:
Catalysis of the reaction: 2-oxoglutarate + chloride + H(+) + L-lysine + O2 = 4-chloro-L-lysine + CO2 + H2O + succinate.


go_id: GO:0062148
term: L-gamma-glutamyl-L-propargylglycine hydroxylase activity
ontology: MF
definition:
Catalysis of the reaction: 2-oxoglutarate + L-gamma-glutamyl-L-propargylglycine + O2 = CO2 + L-gamma-glutamyl-(3R)-L-beta-ethynylserine + succinate.


go_id: GO:0062149
term: detection of stimulus involved in sensory perception of pain
ontology: BP
definition:
The series of events involved in the perception of pain in which a stimulus is received and converted into a molecular signal.


go_id: GO:0062150
term: amorpha-4,11-diene 12-monooxygenase activity
ontology: MF
definition:
Catalysis of the reaction:(+)-amorpha-4,11-diene + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = (+)-artemisinate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase].


go_id: GO:0062152
term: mRNA (cytidine-5-)-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: a cytidine in mRNA + S-adenosyl-L-methionine = a 5-methylcytidine in mRNA + H(+) + S-adenosyl-L-homocysteine.


go_id: GO:0062155
term: curli secretion complex
ontology: CC
definition:
A protein-containing complex that serves as a channel for the secretion of curli. Curli are a fibers that serve as a major component of the extracellular matrix of pellicle biofilms.


go_id: GO:0062157
term: mitochondrial ATP-gated potassium channel complex
ontology: CC
definition:
A protein-containing complex that is capable of the ATP-dependent diffusion of a potassium ion across the mitochondrial inner membrane.


go_id: GO:0062158
term: chloride:proton antiporter activity
ontology: MF
definition:
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: chloride(out) + proton(in) = chloride(in) + proton(out).


go_id: GO:0062159
term: contractile vacuole complex
ontology: CC
definition:
A non-membrane-bounded organelle of eukaryotic cells, especially Protozoa, that fills with water from the cytoplasm and then discharges this externally. One of its functions is osmoregulatory.


go_id: GO:0062160
term: spongiome
ontology: CC
definition:
A cellular anatomical entity which is a network of tubules and vessicles and is part of the contractile vacuole complex. It is involved in the discharge of water externally. One of its functions is osmoregulatory.


go_id: GO:0062163
term: pseudohyphal septin ring assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of septins and associated proteins to form a tight ring-shaped structure that forms in the division plane at the junction between the mother cell and a pseudohyphal projection.


go_id: GO:0062167
term: complement component C1q complex
ontology: CC
definition:
A protein-containing complex composed of six subunits of each of the three homologous polypeptide chains C1QA, C1QB, and C1QB. It is a subunit of the complement C1 complex. In addition to complement activation, C1q appears to have roles in homeostasis and cellular development, superoxide (O2-) production by neutrophils, blood coagulation and neurological synapse pruning.


go_id: GO:0062168
term: negative regulation of plus-end directed microtubule sliding
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of plus-end directed microtubule sliding.


go_id: GO:0062170
term: lutein metabolic process
ontology: BP
definition:
The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform lutein.


go_id: GO:0062176
term: R-loop disassembly
ontology: BP
definition:
A DNA metabolic process that results in the disassembly of R-loops. R-loops are three-stranded nucleic acid structures consisitng of an RNA:DNA heteroduplex and a looped-out non-template strand. Aberrant formation and persistence of R-loops block transcription elongation and cause DNA damage. Mechanisms that resolve R-loops are essential for genome stability.


go_id: GO:0062177
term: radial spoke assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form the radial spoke, a protein complex that links the outer microtubule doublet of the ciliary or flagellum axoneme with the sheath that surrounds the central pair of microtubules.


go_id: GO:0062180
term: 25-hydroxycholecalciferol-23-hydroxylase activity
ontology: MF
definition:
Catalysis of the reaction: calcidiol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = (23S)-23,25-dihydroxycalciol + H2O + 2 oxidized [adrenodoxin].


go_id: GO:0062181
term: 1-alpha,25-dihydroxyvitamin D3 23-hydroxylase activity
ontology: MF
definition:
Catatlysis of the reaction: calcitriol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = 1alpha,23S,25-trihydroxycholecalciferol + H2O + 2 oxidized [adrenodoxin].


go_id: GO:0062182
term: all-trans retinoic acid 4-hydrolase activity
ontology: MF
definition:
Catalysis of the reaction: all-trans-retinoate + O2 + reduced [NADPH--hemoprotein reductase] = all-trans-(4S)-hydroxyretinoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase].


go_id: GO:0062183
term: all-trans retinoic acid 18-hydroxylase activity
ontology: MF
definition:
Catalysis of the reaction: all-trans-retinoate + O2 + reduced [NADPH--hemoprotein reductase] = all-trans-18-hydroxyretinoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase].


go_id: GO:0062184
term: testosterone 16-beta-hydroxylase activity
ontology: MF
definition:
Catalysis of the reaction: O2 + reduced [NADPH--hemoprotein reductase] + testosterone = 16beta,17beta-dihydroxyandrost-4-en-3-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase].


go_id: GO:0062185
term: secalciferol 1-monooxygenase activity
ontology: MF
definition:
Catalysis of the reaction:2 H(+) + O2 + 2 reduced [adrenodoxin] + secalciferol = calcitetrol + H2O + 2 oxidized [adrenodoxin].


go_id: GO:0062187
term: anandamide 8,9 epoxidase activity
ontology: MF
definition:
Catalysis of the reaction: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + N-(8,9-epoxy-5Z,11Z,14Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase].


go_id: GO:0062188
term: anandamide 11,12 epoxidase activity
ontology: MF
definition:
Catalysis of the reaction: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + N-(11,12-epoxy-5Z,8Z,14Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase].


go_id: GO:0062189
term: anandamide 14,15 epoxidase activity
ontology: MF
definition:
Catalysis of the reaction: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + N-(14,15-epoxy-5Z,8Z,11Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase].


go_id: GO:0062191
term: galactoxylomannan biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of the exopolysaccharide galactoxylomannan. Galactoxylomannan is produced by a pathogenic fungus and causes paralysis in some animals.


go_id: GO:0062195
term: microtubule bundle maintenance
ontology: BP
definition:
The organization process that preserves a microtubule bundle in a stable functional or structural state.


go_id: GO:0062197
term: cellular response to chemical stress
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus indicating the organism is under stress.


go_id: GO:0062199
term: chromosome, centromeric inner repeat region
ontology: CC
definition:
The portion of the centromeric region of a chromosome that contains the inner inverted repeat region of a modular centromere and part of the central core surrounding a non-conserved central region. This region is adjacent to the central core, on each chromosome arm.


go_id: GO:0062200
term: RAM/MOR signaling pathway
ontology: BP
definition:
An intracellular signaling pathway that regulates interphase polarized growth and cell separation at the end of cytokinesis through activation of the NDR1/2-related kinase.


go_id: GO:0062201
term: actin wave
ontology: CC
definition:
A cellular anatomical entity that is part of the actin cytoskeleton and results in a wave-like propagation of actin networks. It consists of dynamic structures traveling on the ventral (substrate-attached) side of the cell during cell migration, cytokinesis, adhesion and neurogenesis.


go_id: GO:0062207
term: regulation of pattern recognition receptor signaling pathway
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of a pattern recognition receptor signaling pathway.


go_id: GO:0062208
term: positive regulation of pattern recognition receptor signaling pathway
ontology: BP
definition:
Any process that decreases the rate, frequency or extent of a pattern recognition receptor signaling pathway.


go_id: GO:0062209
ontology: BP
term:
spatial regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination

definition:
Any process that modulates the distribution of sites along the chromosome where meiotic DNA double-strand break formation takes place as part of reciprocal meiotic recombination.


go_id: GO:0062210
term: shoot regeneration
ontology: BP
definition:
The regeneration process by which a damaged or lost shoot regrows or re-differentiates. This process may occur via de-differentiation and subsequent reprogramming of somatic cells or activation of existing undifferentiated (meristematic) cells to produce a new shoot meristem and subsequently a new shoot.


go_id: GO:0062211
term: root regeneration
ontology: BP
definition:
The the regeneration process by which a damaged or lost root regrows or re-differentiates. This process may occur via de-differentiation and subsequent reprogramming of somatic cells or activation of existing undifferentiated (meristematic) cells to form a new root meristem and subsequently new root.


go_id: GO:0062212
term: regulation of mitotic DNA replication initiation from early origin
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of firing from an early origin of replication involved in mitotic DNA replication.


go_id: GO:0062234
term: platelet activating factor catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of platelet activating factor, 2-O-acetyl-1-O-octadecyl-sn-glycero-3-phosphocholine.


go_id: GO:0062235
term: axonemal basal plate assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form an axonemal basal plate.


go_id: GO:0062236
term: ionocyte differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an ionocyte. Ionocytes are specialized epithelial cells that contribute to osmotic homeostasis.


go_id: GO:0062237
term: protein localization to postsynapse
ontology: BP
definition:
Any process in which a protein is transported to, and/or maintained at the postsynapse, the part of a synapse that is part of the post-synaptic cell.


go_id: GO:0062238
term: Smp focus
ontology: CC
definition:
A DNA-binding ribonucleoprotein complex that contains a lncRNA complementary to the bound chromosomal locus and is involved in the tethering homologous chromosomes together during chromosome pairing at meiotic prophase I.


go_id: GO:0062239
term: heterochromatin-nuclear membrane anchor activity
ontology: MF
definition:
Binding to heterochromatin and the nuclear inner membrane, in order to establish and maintain the heterochromatin location and organization.


go_id: GO:0062240
term: euchromatin-nuclear membrane anchor activity
ontology: MF
definition:
Binding to euchromatin and the nuclear inner membrane, in order to establish and maintain the euchromatin location and organization.


go_id: GO:0062241
term: double strand break-nuclear membrane anchor activity
ontology: MF
definition:
Binding to DNA double strand breaks and the nuclear inner membrane, in order to facilitate DNA repair.


go_id: GO:0062242
term: double membrane vesicle viral factory membrane
ontology: CC
definition:
One of the two endoplasmic reticulum-derived lipid bilayer membranes that bound a double membrane vesicle viral factory.


go_id: GO:0062243
term: double membrane vesicle viral factory outer membrane
ontology: CC
definition:
The outer of the two endoplasmic reticulum-derived lipid bilayer membranes that bound a double membrane vesicle viral factory.


go_id: GO:0062245
term: double membrane vesicle viral factory inner membrane
ontology: CC
definition:
The inner of the two endoplasmic reticulum-derived lipid bilayer membranes that bound a double membrane vesicle viral factory.


go_id: GO:0062248
term: cleistothecium formation
ontology: BP
definition:
The process of producing a cleistothecium, a closed sexual fruiting body that contains ascospores in linear asci. Cleistothecia are present in some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.


go_id: GO:0065001
term: specification of axis polarity
ontology: BP
definition:
The pattern specification process in which the polarity of a body or organ axis is established and maintained.


go_id: GO:0065002
term: intracellular protein transmembrane transport
ontology: BP
definition:
The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.


go_id: GO:0065003
term: protein-containing complex assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.


go_id: GO:0065004
term: protein-DNA complex assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex.


go_id: GO:0065005
term: protein-lipid complex assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of proteins and lipids to form a protein-lipid complex.


go_id: GO:0065008
term: regulation of biological quality
ontology: BP
definition:
Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc.


go_id: GO:0065009
term: regulation of molecular function
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.


go_id: GO:0065010
term: extracellular membrane-bounded organelle
ontology: CC
definition:
Organized structure of distinctive morphology and function, bounded by a lipid bilayer membrane and occurring outside the cell.


go_id: GO:0070001
term: aspartic-type peptidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile.


go_id: GO:0070002
term: glutamic-type peptidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism involving a glutamate/glutamine catalytic dyad.


go_id: GO:0070003
term: threonine-type peptidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the hydroxyl group of a threonine residue at the active center acts as a nucleophile.


go_id: GO:0070004
term: cysteine-type exopeptidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of C- or N-terminal peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.


go_id: GO:0070005
term: cysteine-type aminopeptidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.


go_id: GO:0070006
term: metalloaminopeptidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.


go_id: GO:0070007
term: glutamic-type endopeptidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of internal peptide bonds in a polypeptide chain by a mechanism involving a glutamate/glutamine catalytic dyad.


go_id: GO:0070008
term: serine-type exopeptidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).


go_id: GO:0070009
term: serine-type aminopeptidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).


go_id: GO:0070012
term: oligopeptidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of a peptide bond in an oligopeptide, i.e. a molecule containing a small number (2 to 20) of amino acid residues connected by peptide bonds.


go_id: GO:0070014
term: sucrase-isomaltase complex
ontology: CC
definition:
A protein complex that possesses oligo-1,6-glucosidase activity; the complex is a heterodimer located in the cell membrane, and is formed by proteolytic cleavage of a single precursor polypeptide. The two subunits have different substrate specificities.


go_id: GO:0070016
term: armadillo repeat domain binding
ontology: MF
definition:
Binding to an armadillo repeat domain, an approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity protein armadillo. Arm-repeat proteins are involved in various processes, including intracellular signalling and cytoskeletal regulation.


go_id: GO:0070021
term: transforming growth factor beta ligand-receptor complex
ontology: CC
definition:
A protein complex that is formed by the association of a TGF-beta dimeric ligand with 2 molecules of each receptor molecule, TGF-beta type I receptor and TGF-beta type II receptor. The receptor molecules may form homo- or heterodimers but only once bound by the ligand.


go_id: GO:0070023
term: interleukin-12-interleukin-12 receptor complex
ontology: CC
definition:
A protein complex that is formed by the association of a heterodimeric interleukin-12 receptor complex with an interleukin-12 heterodimer.


go_id: GO:0070024
term: CD19-Vav-PIK3R1 complex
ontology: CC
definition:
A protein complex that contains the cell surface signaling molecule CD19, the Ras guanine nucleotide exchange factor Vav, and the regulatory subunit alpha of phosphatidylinositol 3-kinase (PI3K).


go_id: GO:0070027
term: carbon monoxide sensor activity
ontology: MF
definition:
Binding to and responding, e.g. by conformational change, to changes in the cellular level of carbon monoxide (CO).


go_id: GO:0070032
term: synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex
ontology: CC
definition:
A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, and complexin I (or orthologs thereof).


go_id: GO:0070033
term: synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex
ontology: CC
definition:
A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, and complexin II (or orthologs thereof).


go_id: GO:0070037
term: rRNA (pseudouridine) methyltransferase activity
ontology: MF
definition:
Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a pseudouridine residue in an rRNA molecule.


go_id: GO:0070038
term: rRNA (pseudouridine-N3-)-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N3-methylpseudouridine.


go_id: GO:0070039
term: rRNA (guanosine-2'-O-)-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methylguanosine.


go_id: GO:0070040
term: rRNA (adenine-C2-)-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: 2 S-adenosyl-L-methionine + adenine(2503) in 23S rRNA = S-adenosyl-L-homocysteine + 5'-deoxyadenosine + L-methionine + rRNA containing C2-methyladenine(2503) in 23S rRNA.


go_id: GO:0070041
term: rRNA (uridine-C5-)-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing C5-methyluridine.


go_id: GO:0070042
term: rRNA (uridine-N3-)-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N3-methyluridine.


go_id: GO:0070043
term: rRNA (guanine-N7-)-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N7-methylguanine.


go_id: GO:0070044
term: synaptobrevin 2-SNAP-25-syntaxin-1a complex
ontology: CC
definition:
A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 1a (or orthologs thereof).


go_id: GO:0070045
term: synaptobrevin 2-SNAP-25-syntaxin-2 complex
ontology: CC
definition:
A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 2 (or orthologs thereof).


go_id: GO:0070046
term: synaptobrevin 2-SNAP-25-syntaxin-3 complex
ontology: CC
definition:
A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 3 (or orthologs thereof).


go_id: GO:0070047
term: synaptobrevin 2-SNAP-25-syntaxin-4 complex
ontology: CC
definition:
A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 4 (or orthologs thereof).


go_id: GO:0070050
term: neuron cellular homeostasis
ontology: BP
definition:
The cellular homeostatic process that preserves a neuron in a stable, differentiated functional and structural state.


go_id: GO:0070051
term: fibrinogen binding
ontology: MF
definition:
Binding to fibrinogen, a highly soluble hexameric glycoprotein complex that is found in blood plasma and is converted to fibrin by thrombin in the coagulation cascade.


go_id: GO:0070054
term: mRNA splicing, via endonucleolytic cleavage and ligation
ontology: BP
definition:
Splicing of mRNA substrates via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons.


go_id: GO:0070056
term: prospore membrane leading edge
ontology: CC
definition:
The region of the prospore membrane that extends to surround the spore nucleus; coated with specific proteins that are thought to play a role in prospore membrane organization.


go_id: GO:0070057
term: prospore membrane spindle pole body attachment site
ontology: CC
definition:
The region of the prospore membrane to which the spindle pole body (SPB) is anchored; the prospore membrane extends from the SPB attachment site to surround the spore nucleus.


go_id: GO:0070058
term: tRNA gene clustering
ontology: BP
definition:
The process in which tRNA genes, which are not linearly connected on the chromosome, are transported in three dimensions to, and maintained together in, the nucleolus. This clustered positioning leads to transcriptional silencing of nearby RNA polymerase II promoters (termed tRNA gene mediated (tgm) silencing) in S. cerevisiae.


go_id: GO:0070059
term: intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
ontology: BP
definition:
The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to a stimulus indicating endoplasmic reticulum (ER) stress, and ends when the execution phase of apoptosis is triggered. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.


go_id: GO:0070060
term: 'de novo' actin filament nucleation
ontology: BP
definition:
The actin nucleation process in which actin monomers combine in the absence of any existing actin filaments; elongation of the actin oligomer formed by nucleation leads to the formation of an unbranched filament.


go_id: GO:0070062
term: extracellular exosome
ontology: CC
definition:
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.


go_id: GO:0070064
term: proline-rich region binding
ontology: MF
definition:
Binding to a proline-rich region, i.e. a region that contains a high proportion of proline residues, in a protein.


go_id: GO:0070066
term: cellubrevin-VAMP4-endobrevin-syntaxin-6 complex
ontology: CC
definition:
A SNARE complex that contains cellubrevin (VAMP3), VAMP4, endobrevin (VAMP8), and syntaxin 6 (or orthologs thereof).


go_id: GO:0070069
term: cytochrome complex
ontology: CC
definition:
A protein complex in which at least one of the proteins is a cytochrome, i.e. a heme-containing protein involved in catalysis of redox reactions.


go_id: GO:0070070
term: proton-transporting V-type ATPase complex assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a proton-transporting V-type ATPase complex, proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across a concentration gradient.


go_id: GO:0070071
term: proton-transporting two-sector ATPase complex assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a proton-transporting two-sector ATPase complex, a large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane.


go_id: GO:0070072
term: vacuolar proton-transporting V-type ATPase complex assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a vacuolar proton-transporting V-type ATPase complex, proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across the vacuolar membrane.


go_id: GO:0070074
term: mononeme
ontology: CC
definition:
A secretory organelle that forms part of the apical complex; a small, threadlike structure located is close proximity to the subpellicular microtubules. Its contents include a rhomboid protease (PfROM1 in Plasmodium falciparum) that moves from the lateral asymmetric localization to the merozoite apical pole and the posterior pole upon release of merozoites from schizonts.


go_id: GO:0070075
term: tear secretion
ontology: BP
definition:
The regulated release of the aqueous layer of the tear film from the lacrimal glands. Tears are the liquid product of a process of lacrimation to clean and lubricate the eyes. Tear fluid contains water, mucin, lipids, lysozyme, lactoferrin, lipocalin, lacritin, immunoglobulins, glucose, urea, sodium, and potassium.


go_id: GO:0070078
term: histone H3-R2 demethylation
ontology: BP
definition:
The modification of histone H3 by the removal of a methyl group from arginine at position 2 of the histone.


go_id: GO:0070079
term: histone H4-R3 demethylation
ontology: BP
definition:
The modification of histone H4 by the removal of a methyl group from arginine at position 3 of the histone.


go_id: GO:0070080
term: titin Z domain binding
ontology: MF
definition:
Binding to a titin Z protein domain, which recognizes and binds to the C-terminal calmodulin-like domain of alpha-actinin-2 (Act-EF34), adopts a helical structure, and binds in a groove formed by the two planes between the helix pairs of Act-EF34.


go_id: GO:0070081
term: clathrin-sculpted monoamine transport vesicle
ontology: CC
definition:
A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing monoamines.


go_id: GO:0070084
term: protein initiator methionine removal
ontology: BP
definition:
The protein modification process in which the translation-initiating methionine or formylmethionine residue is removed from a protein.


go_id: GO:0070086
term: ubiquitin-dependent endocytosis
ontology: BP
definition:
Endocytosis of a protein that requires the substrate to be modified by ubiquitination. Several plasma membrane proteins, including cell surface permeases and some receptors, are targeted for internalization by endocytosis, and are thereafter delivered to the vacuole or lysosome, where they are degraded.


go_id: GO:0070087
term: chromo shadow domain binding
ontology: MF
definition:
Binding to a chromo shadow domain, a protein domain that is distantly related, and found in association with, the chromo domain.


go_id: GO:0070088
term: PHA granule
ontology: CC
definition:
An inclusion body located in the cytoplasm that consists of polyhydroxyalkanoate (PHA) molecules and associated proteins, surrounded by a phospholipid monolayer; the proteins include PHA synthase, PHA depolymerase and 3HB-oligomer hydroxylase, phasins (PhaPs), which are thought to be the major structural proteins of the membrane surrounding the inclusion, and the regulator of phasin expression PhaR.


go_id: GO:0070089
term: chloride-activated potassium channel activity
ontology: MF
definition:
Enables the chloride concentration-regulatable energy-independent passage of potassium ions across a lipid bilayer down a concentration gradient.


go_id: GO:0070090
term: metaphase plate
ontology: CC
definition:
The intracellular plane, located halfway between the poles of the spindle, where chromosomes align during metaphase of mitotic or meiotic nuclear division.


go_id: GO:0070091
term: glucagon secretion
ontology: BP
definition:
The regulated release of glucagon from secretory granules in the A (alpha) cells of the pancreas (islets of Langerhans).


go_id: GO:0070093
term: negative regulation of glucagon secretion
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of glucagon.


go_id: GO:0070094
term: positive regulation of glucagon secretion
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the regulated release of glucagon.


go_id: GO:0070096
term: mitochondrial outer membrane translocase complex assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form a mitochondrial outer membrane translocase complex.


go_id: GO:0070098
term: chemokine-mediated signaling pathway
ontology: BP
definition:
The series of molecular signals initiated by a chemokine binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


go_id: GO:0070102
term: interleukin-6-mediated signaling pathway
ontology: BP
definition:
The series of molecular signals initiated by interleukin-6 binding to a receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


go_id: GO:0070103
term: regulation of interleukin-6-mediated signaling pathway
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of an interleukin-6-mediated signaling pathway.


go_id: GO:0070104
term: negative regulation of interleukin-6-mediated signaling pathway
ontology: BP
definition:
Any process that decreases the rate, frequency or extent of an interleukin-6-mediated signaling pathway.


go_id: GO:0070105
term: positive regulation of interleukin-6-mediated signaling pathway
ontology: BP
definition:
Any process that increases the rate, frequency or extent of an interleukin-6-mediated signaling pathway.


go_id: GO:0070106
term: interleukin-27-mediated signaling pathway
ontology: BP
definition:
The series of molecular signals initiated by interleukin-27 binding to a receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


go_id: GO:0070107
term: regulation of interleukin-27-mediated signaling pathway
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of an interleukin-27-mediated signaling pathway.


go_id: GO:0070108
term: negative regulation of interleukin-27-mediated signaling pathway
ontology: BP
definition:
Any process that decreases the rate, frequency or extent of an interleukin-27-mediated signaling pathway.


go_id: GO:0070109
term: positive regulation of interleukin-27-mediated signaling pathway
ontology: BP
definition:
Any process that increases the rate, frequency or extent of an interleukin-27-mediated signaling pathway.


go_id: GO:0070110
term: ciliary neurotrophic factor receptor complex
ontology: CC
definition:
A protein complex that acts as a receptor for the cytokine ciliary neurotrophic factor (CNTF). In humans the receptor complex is a hexamer composed of two molecules each of CNTF and CNTFR and one molecule each of gp130 and LIFR.


go_id: GO:0070111
term: organellar chromatophore
ontology: CC
definition:
A bacteroid-containing symbiosome in which the bacterial component is a genetically highly reduced cyanobacterium that is photosynthetically active and incapable of an independent existence outside its host. The chromatophore functions as a photosynthetic organelle, and has been found and characterized in the amoeba Paulinella chromatophora.


go_id: GO:0070114
term: organellar chromatophore outer membrane
ontology: CC
definition:
The outer, i.e. cytoplasm-facing, of the two lipid bilayers surrounding an organellar chromatophore.


go_id: GO:0070120
term: ciliary neurotrophic factor-mediated signaling pathway
ontology: BP
definition:
The series of molecular signals initiated by the binding of a ciliary neurotrophic factor (CNTF) to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


go_id: GO:0070121
term: Kupffer's vesicle development
ontology: BP
definition:
The progression of the Kupffer's vesicle over time from its initial formation until its mature state. The Kupffer's vesicle is a small but distinctive epithelial sac containing fluid, located midventrally posterior to the yolk cell or its extension, and transiently present during most of the segmentation period.


go_id: GO:0070123
term: transforming growth factor beta receptor activity, type III
ontology: MF
definition:
Combining with transforming growth factor beta to initiate a change in cell activity; facilitates ligand binding to type I and type II TGF-beta receptors.


go_id: GO:0070124
term: mitochondrial translational initiation
ontology: BP
definition:
The process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion. This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA.


go_id: GO:0070125
term: mitochondrial translational elongation
ontology: BP
definition:
The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion.


go_id: GO:0070126
term: mitochondrial translational termination
ontology: BP
definition:
The process resulting in the release of a polypeptide chain from the ribosome in a mitochondrion, usually in response to a termination codon (note that mitochondria use variants of the universal genetic code that differ between different taxa).


go_id: GO:0070127
term: tRNA aminoacylation for mitochondrial protein translation
ontology: BP
definition:
The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, to be used in ribosome-mediated polypeptide synthesis in a mitochondrion.


go_id: GO:0070129
term: regulation of mitochondrial translation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion.


go_id: GO:0070130
term: negative regulation of mitochondrial translation
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion.


go_id: GO:0070131
term: positive regulation of mitochondrial translation
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion.


go_id: GO:0070132
term: regulation of mitochondrial translational initiation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion.


go_id: GO:0070133
term: negative regulation of mitochondrial translational initiation
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion.


go_id: GO:0070134
term: positive regulation of mitochondrial translational initiation
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion.


go_id: GO:0070135
term: beta-1,2-oligomannoside metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving beta-1,2-linked oligomannosides, which are found in fungal cell wall phosphopeptidomannan and phospholipomannan.


go_id: GO:0070136
term: beta-1,2-oligomannoside biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of beta-1,2-linked oligomannosides, which are found in fungal cell wall phosphopeptidomannan and phospholipomannan.


go_id: GO:0070137
term: ubiquitin-like protein-specific endopeptidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of peptide bonds between an alpha-carboxyl group and an alpha-amino group within a small protein such as ubiquitin or a ubiquitin-like protein (e.g. APG8, ISG15, NEDD8, SUMO).


go_id: GO:0070139
term: SUMO-specific endopeptidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of peptide bonds between an alpha-carboxyl group and an alpha-amino group within the small conjugating protein SUMO.


go_id: GO:0070141
term: response to UV-A
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-A radiation stimulus. UV-A radiation (UV-A light) spans the wavelengths 315 to 400 nm.


go_id: GO:0070143
term: mitochondrial alanyl-tRNA aminoacylation
ontology: BP
definition:
The process of coupling alanine to alanyl-tRNA in a mitochondrion, catalyzed by alanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.


go_id: GO:0070144
term: mitochondrial arginyl-tRNA aminoacylation
ontology: BP
definition:
The process of coupling arginine to arginyl-tRNA in a mitochondrion, catalyzed by arginyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.


go_id: GO:0070145
term: mitochondrial asparaginyl-tRNA aminoacylation
ontology: BP
definition:
The process of coupling asparagine to asparaginyl-tRNA in a mitochondrion, catalyzed by asparaginyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.


go_id: GO:0070146
term: mitochondrial aspartyl-tRNA aminoacylation
ontology: BP
definition:
The process of coupling aspartate to aspartyl-tRNA in a mitochondrion, catalyzed by aspartyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.


go_id: GO:0070147
term: mitochondrial cysteinyl-tRNA aminoacylation
ontology: BP
definition:
The process of coupling cysteine to cysteinyl-tRNA in a mitochondrion, catalyzed by cysteinyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.


go_id: GO:0070148
term: mitochondrial glutaminyl-tRNA aminoacylation
ontology: BP
definition:
The process of coupling glutamine to glutaminyl-tRNA in a mitochondrion, catalyzed by glutaminyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.


go_id: GO:0070149
term: mitochondrial glutamyl-tRNA aminoacylation
ontology: BP
definition:
The process of coupling glutamate to glutamyl-tRNA in a mitochondrion, catalyzed by glutamyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.


go_id: GO:0070150
term: mitochondrial glycyl-tRNA aminoacylation
ontology: BP
definition:
The process of coupling glycine to glycyl-tRNA in a mitochondrion, catalyzed by glycyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.


go_id: GO:0070151
term: mitochondrial histidyl-tRNA aminoacylation
ontology: BP
definition:
The process of coupling histidine to histidyl-tRNA in a mitochondrion, catalyzed by histidyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.


go_id: GO:0070152
term: mitochondrial isoleucyl-tRNA aminoacylation
ontology: BP
definition:
The process of coupling isoleucine to isoleucyl-tRNA in a mitochondrion, catalyzed by isoleucyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.


go_id: GO:0070153
term: mitochondrial leucyl-tRNA aminoacylation
ontology: BP
definition:
The process of coupling leucine to leucyl-tRNA in a mitochondrion, catalyzed by leucyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.


go_id: GO:0070154
term: mitochondrial lysyl-tRNA aminoacylation
ontology: BP
definition:
The process of coupling lysine to lysyl-tRNA in a mitochondrion, catalyzed by lysyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.


go_id: GO:0070155
term: mitochondrial methionyl-tRNA aminoacylation
ontology: BP
definition:
The process of coupling methionine to methionyl-tRNA in a mitochondrion, catalyzed by methionyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.


go_id: GO:0070156
term: mitochondrial phenylalanyl-tRNA aminoacylation
ontology: BP
definition:
The process of coupling phenylalanine to phenylalanyl-tRNA in a mitochondrion, catalyzed by phenylalanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.


go_id: GO:0070157
term: mitochondrial prolyl-tRNA aminoacylation
ontology: BP
definition:
The process of coupling proline to prolyl-tRNA in a mitochondrion, catalyzed by prolyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.


go_id: GO:0070158
term: mitochondrial seryl-tRNA aminoacylation
ontology: BP
definition:
The process of coupling serine to seryl-tRNA in a mitochondrion, catalyzed by seryl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.


go_id: GO:0070159
term: mitochondrial threonyl-tRNA aminoacylation
ontology: BP
definition:
The process of coupling threonine to threonyl-tRNA in a mitochondrion, catalyzed by threonyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.


go_id: GO:0070160
term: tight junction
ontology: CC
definition:
A cell-cell junction that seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other.


go_id: GO:0070161
term: anchoring junction
ontology: CC
definition:
A cell junction that mechanically attaches a cell (and its cytoskeleton) to neighboring cells or to the extracellular matrix.


go_id: GO:0070163
term: regulation of adiponectin secretion
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the regulated release of adiponectin from a cell.


go_id: GO:0070164
term: negative regulation of adiponectin secretion
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of adiponectin from a cell.


go_id: GO:0070165
term: positive regulation of adiponectin secretion
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the regulated release of adiponectin from a cell.


go_id: GO:0070166
term: enamel mineralization
ontology: BP
definition:
The process in which calcium salts, mainly carbonated hydroxyapatite, are deposited in tooth enamel.


go_id: GO:0070167
term: regulation of biomineral tissue development
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds.


go_id: GO:0070168
term: negative regulation of biomineral tissue development
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds.


go_id: GO:0070169
term: positive regulation of biomineral tissue development
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds.


go_id: GO:0070170
term: regulation of tooth mineralization
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures.


go_id: GO:0070171
term: negative regulation of tooth mineralization
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures.


go_id: GO:0070172
term: positive regulation of tooth mineralization
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures.


go_id: GO:0070173
term: regulation of enamel mineralization
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel.


go_id: GO:0070174
term: negative regulation of enamel mineralization
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel.


go_id: GO:0070175
term: positive regulation of enamel mineralization
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel.


go_id: GO:0070176
term: DRM complex
ontology: CC
definition:
A transcriptional repressor complex that contains the lin-9, lin-35, lin-37, lin-52, lin-53, lin-5is involved in 4-, dpl-1 and efl-1 proteins, and is involved in cell fate specification.


go_id: GO:0070177
term: contractile vacuole discharge
ontology: BP
definition:
The regulated release of water from a contractile vacuole to the outside of a cell by fusion of the contractile vacuole membrane with the plasma membrane.


go_id: GO:0070178
term: D-serine metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving D-serine, the D-enantiomer of serine, i.e. (2R)-2-amino-3-hydroxypropanoic acid.


go_id: GO:0070179
term: D-serine biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of D-serine, the D-enantiomer of serine, i.e. (2R)-2-amino-3-hydroxypropanoic acid. D-serine is often formed by racemization of L-serine.


go_id: GO:0070180
term: large ribosomal subunit rRNA binding
ontology: MF
definition:
Binding to large ribosomal subunit RNA (LSU rRNA), a constituent of the large ribosomal subunit. In S. cerevisiae, this is the 25S rRNA.


go_id: GO:0070181
term: small ribosomal subunit rRNA binding
ontology: MF
definition:
Binding to small ribosomal subunit RNA (SSU rRNA), a constituent of the small ribosomal subunit. In S. cerevisiae, this is the 18S rRNA.


go_id: GO:0070183
term: mitochondrial tryptophanyl-tRNA aminoacylation
ontology: BP
definition:
The process of coupling tryptophan to tryptophanyl-tRNA in a mitochondrion, catalyzed by tryptophanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.


go_id: GO:0070184
term: mitochondrial tyrosyl-tRNA aminoacylation
ontology: BP
definition:
The process of coupling tyrosine to tyrosyl-tRNA in a mitochondrion, catalyzed by tyrosyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.


go_id: GO:0070185
term: mitochondrial valyl-tRNA aminoacylation
ontology: BP
definition:
The process of coupling valine to valyl-tRNA in a mitochondrion, catalyzed by valyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.


go_id: GO:0070186
term: growth hormone activity
ontology: MF
definition:
The action characteristic of growth hormone, a peptide hormone that is secreted by the anterior pituitary or the placenta into the circulation, and binds to membrane receptors in target tissues to stimulate body growth.


go_id: GO:0070187
term: shelterin complex
ontology: CC
definition:
A nuclear telomere cap complex that is formed by the association of telomeric ssDNA- and dsDNA-binding proteins with telomeric DNA, and is involved in telomere protection and recruitment of telomerase. The complex is known to contain TERF1, TERF2, POT1, RAP1, TINF2 and ACD in mammalian cells, and Pot1, Tpz1, Rap1, Rif1, Rif2 and Taz1 in Saccharomyces. Taz1 and Rap1 (or their mammalian equivalents) form a dsDNA-binding subcomplex, Pot1 and Tpz1 form an ssDNA-binding subcomplex, and the two subcomplexes are bridged by Poz1, which acts as an effector molecule along with Ccq1.


go_id: GO:0070189
term: kynurenine metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving kynurenine, the amino acid 3-(2-aminobenzoyl)-alanine.


go_id: GO:0070191
term: methionine-R-sulfoxide reductase activity
ontology: MF
definition:
Catalysis of the reaction: L-methionine R-oxide + thioredoxin = L-methionine + thioredoxin disulfide; can act on free oxidized methionine with specificity for the R enantiomer; does not act on oxidized methionine in peptide linkage. Thioredoxin disulfide is the oxidized form of thioredoxin.


go_id: GO:0070193
term: synaptonemal complex organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synaptonemal complex. A synaptonemal complex is a proteinaceous scaffold formed between homologous chromosomes during meiosis.


go_id: GO:0070196
term: eukaryotic translation initiation factor 3 complex assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form the eukaryotic translation initiation factor 3 complex.


go_id: GO:0070197
term: meiotic attachment of telomere to nuclear envelope
ontology: BP
definition:
The meiotic cell cycle process in which physical connections are formed between telomeric heterochromatin and the nuclear envelope, facilitating bouquet formation.


go_id: GO:0070198
term: protein localization to chromosome, telomeric region
ontology: BP
definition:
Any process in which a protein is transported to, or maintained at, the telomeric region of a chromosome.


go_id: GO:0070201
term: regulation of establishment of protein localization
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location.


go_id: GO:0070202
term: regulation of establishment of protein localization to chromosome
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location on a chromosome.


go_id: GO:0070203
term: regulation of establishment of protein localization to telomere
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location in the telomeric region of a chromosome.


go_id: GO:0070204
term: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity
ontology: MF
definition:
Catalysis of the reaction: 2-oxoglutarate + H(+) + isochorismate = 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate + CO(2).


go_id: GO:0070205
term: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity
ontology: MF
definition:
Catalysis of the reaction: 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate = (1R,6R)-2-succinyl-6-hydroxycyclohexa-2,4-diene-1-carboxylate + pyruvate.


go_id: GO:0070206
term: protein trimerization
ontology: BP
definition:
The formation of a protein trimer, a macromolecular structure consisting of three noncovalently associated identical or nonidentical subunits.


go_id: GO:0070207
term: protein homotrimerization
ontology: BP
definition:
The formation of a protein homotrimer, a macromolecular structure consisting of three noncovalently associated identical subunits.


go_id: GO:0070208
term: protein heterotrimerization
ontology: BP
definition:
The formation of a protein heterotrimer, a macromolecular structure consisting of three noncovalently associated subunits, of which not all are identical.


go_id: GO:0070209
term: ASTRA complex
ontology: CC
definition:
A protein complex that is part of the chromatin remodeling machinery; the acronym stands for ASsembly of Tel, Rvb and Atm-like kinase. In Saccharomyces cerevisiae this complex includes Rvb1p, Rvb2p, Tra1p, Tel2p, Asa1p, Ttilp and Tti2p.


go_id: GO:0070210
term: Rpd3L-Expanded complex
ontology: CC
definition:
A protein complex that contains a histone deacetylase and is part of the chromatin remodeling machinery. In Saccharomyces cerevisiae this complex contains the Rpd3p, Sin3p, Ume1p, Pho23p, Sap30p, Sds3p, Cti6p, Rxt2p, Rxt3p, Dep1p, Ume6p, Ash1p, Dot6p, Snt1, Sif2p, Set3p, Hos2p, Tos4p and Tod6p proteins.


go_id: GO:0070211
term: Snt2C complex
ontology: CC
definition:
A histone deacetylase complex that is part of the chromatin remodeling machinery. In Saccharomyces cerevisiae this complex contains Snt2p, Ecm5p and Rpd3p.


go_id: GO:0070212
term: protein poly-ADP-ribosylation
ontology: BP
definition:
The transfer of multiple ADP-ribose residues from NAD to a protein amino acid, forming a poly(ADP-ribose) chain.


go_id: GO:0070213
term: protein auto-ADP-ribosylation
ontology: BP
definition:
The ADP-ribosylation by a protein of one or more of its own amino acid residues, or residues on an identical protein.


go_id: GO:0070214
term: CSK-GAP-A.p62 complex
ontology: CC
definition:
A protein complex that contains the protein-tyrosine kinase CSK and the GTPase-activating protein (GAP)-associated p62 (GAP-A.p62); may mediate translocation of proteins, including GAP and CSK, to membrane or cytoskeletal regions upon c-Src activation.


go_id: GO:0070217
term: transcription factor TFIIIB complex assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form a transcription factor TFIIIB complex.


go_id: GO:0070218
term: sulfide ion homeostasis
ontology: BP
definition:
Any process involved in the maintenance of an internal steady state of sulfide ions within an organism or cell.


go_id: GO:0070219
term: cellular sulfide ion homeostasis
ontology: BP
definition:
Any process involved in the maintenance of an internal steady state of sulfide ions at the level of a cell.


go_id: GO:0070220
term: aerobic sulfur oxidation
ontology: BP
definition:
A sulfur oxidation process that proceeds via the reaction catalyzed by sulfur dioxygenase, and requires the presence of oxygen.


go_id: GO:0070221
term: sulfide oxidation, using sulfide:quinone oxidoreductase
ontology: BP
definition:
A sulfide oxidation process that proceeds via the reaction catalyzed by sulfide:quinone oxidoreductase.


go_id: GO:0070224
term: sulfide:quinone oxidoreductase activity
ontology: MF
definition:
Catalysis of the reaction: H2S (hydrogen sulfide) + a quinone = S0 (sulfane sulfur) + a hydroquinone.


go_id: GO:0070227
term: lymphocyte apoptotic process
ontology: BP
definition:
Any apoptotic process in a lymphocyte, a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin.


go_id: GO:0070229
term: negative regulation of lymphocyte apoptotic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte death by apoptotic process.


go_id: GO:0070230
term: positive regulation of lymphocyte apoptotic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of lymphocyte death by apoptotic process.


go_id: GO:0070231
term: T cell apoptotic process
ontology: BP
definition:
Any apoptotic process in a T cell, a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex.


go_id: GO:0070233
term: negative regulation of T cell apoptotic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of T cell death by apoptotic process.


go_id: GO:0070234
term: positive regulation of T cell apoptotic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of T cell death by apoptotic process.


go_id: GO:0070236
term: negative regulation of activation-induced cell death of T cells
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of activation-induced cell death of T cells.


go_id: GO:0070237
term: positive regulation of activation-induced cell death of T cells
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of activation-induced cell death of T cells.


go_id: GO:0070238
term: activated T cell autonomous cell death
ontology: BP
definition:
A T cell apoptotic process that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen via the accumulation of pro-apoptotic gene products and decrease in anti-apoptotic gene products.


go_id: GO:0070240
term: negative regulation of activated T cell autonomous cell death
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of activated T cell autonomous cell death.


go_id: GO:0070241
term: positive regulation of activated T cell autonomous cell death
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of activated T cell autonomous cell death.


go_id: GO:0070244
term: negative regulation of thymocyte apoptotic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of thymocyte death by apoptotic process.


go_id: GO:0070245
term: positive regulation of thymocyte apoptotic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of thymocyte death by apoptotic process.


go_id: GO:0070246
term: natural killer cell apoptotic process
ontology: BP
definition:
Any apoptotic process in a natural killer cell, a lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation.


go_id: GO:0070247
term: regulation of natural killer cell apoptotic process
ontology: BP
definition:
Any process that modulates the occurrence or rate of natural killer cell death by apoptotic process.


go_id: GO:0070248
term: negative regulation of natural killer cell apoptotic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell death by apoptotic process.


go_id: GO:0070249
term: positive regulation of natural killer cell apoptotic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of natural killer cell death by apoptotic process.


go_id: GO:0070250
term: mating projection membrane
ontology: CC
definition:
The portion of the plasma membrane surrounding a mating projection, the projection formed by unicellular fungi in response to mating pheromone.


go_id: GO:0070252
term: actin-mediated cell contraction
ontology: BP
definition:
The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of all or part of the cell body.


go_id: GO:0070254
term: mucus secretion
ontology: BP
definition:
The regulated release of mucus by the mucosa. Mucus is a viscous slimy secretion consisting of mucins and various inorganic salts dissolved in water, with suspended epithelial cells and leukocytes. The mucosa, or mucous membrane, is the membrane covered with epithelium that lines the tubular organs of the body. Mucins are carbohydrate-rich glycoproteins that have a lubricating and protective function.


go_id: GO:0070255
term: regulation of mucus secretion
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the regulated release of mucus from a cell or a tissue.


go_id: GO:0070256
term: negative regulation of mucus secretion
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of mucus from a cell or a tissue.


go_id: GO:0070257
term: positive regulation of mucus secretion
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the regulated release of mucus from a cell or a tissue.


go_id: GO:0070258
term: inner membrane pellicle complex
ontology: CC
definition:
A membrane structure formed of two closely aligned lipid bilayers that lie beneath the plasma membrane and form part of the pellicle surrounding an apicomplexan parasite cell.


go_id: GO:0070259
term: tyrosyl-DNA phosphodiesterase activity
ontology: MF
definition:
Catalysis of the hydrolysis of phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between a DNA topoisomerase and DNA.


go_id: GO:0070260
term: 5'-tyrosyl-DNA phosphodiesterase activity
ontology: MF
definition:
Catalysis of the hydrolysis of 5'-phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between DNA topoisomerase II and DNA.


go_id: GO:0070263
term: external side of fungal-type cell wall
ontology: CC
definition:
The side of the fungal-type cell wall that is opposite to the side that faces the cell and its contents.


go_id: GO:0070264
term: transcription factor TFIIIE complex
ontology: CC
definition:
A transcription factor complex that is involved in regulating transcription from RNA polymerase III (Pol III) promoters. TFIIIE contains a specific subset of ribosomal proteins.


go_id: GO:0070265
term: necrotic cell death
ontology: BP
definition:
A type of cell death that is morphologically characterized by an increasingly translucent cytoplasm, swelling of organelles, minor ultrastructural modifications of the nucleus (specifically, dilatation of the nuclear membrane and condensation of chromatin into small, irregular, circumscribed patches) and increased cell volume (oncosis), culminating in the disruption of the plasma membrane and subsequent loss of intracellular contents. Necrotic cells do not fragment into discrete corpses as their apoptotic counterparts do. Moreover, their nuclei remain intact and can aggregate and accumulate in necrotic tissues.


go_id: GO:0070266
term: necroptotic process
ontology: BP
definition:
A programmed necrotic cell death process which begins when a cell receives a signal (e.g. a ligand binding to a death receptor or to a Toll-like receptor), and proceeds through a series of biochemical events (signaling pathways), characterized by activation of receptor-interacting serine/threonine-protein kinase 1 and/or 3 (RIPK1/3, also called RIP1/3) and by critical dependence on mixed lineage kinase domain-like (MLKL), and which typically lead to common morphological features of necrotic cell death. The process ends when the cell has died. The process is divided into a signaling phase, and an execution phase, which is triggered by the former.


go_id: GO:0070267
term: oncosis
ontology: BP
definition:
A cellular process that results in swelling of the cell body, and that is morphologically characteristic of necrotic cell death.


go_id: GO:0070268
term: cornification
ontology: BP
definition:
A type of programmed cell death that occurs in the epidermis, morphologically and biochemically distinct from apoptosis. It leads to the formation of corneocytes, i.e. dead keratinocytes containing an amalgam of specific proteins (e.g., keratin, loricrin, SPR and involucrin) and lipids (e.g., fatty acids and ceramides), which are necessary for the function of the cornified skin layer (mechanical resistance, elasticity, water repellence and structural stability).


go_id: GO:0070269
term: pyroptosis
ontology: BP
definition:
A caspase-1-dependent cell death subroutine that is associated with the generation of pyrogenic mediators such as IL-1beta and IL-18.


go_id: GO:0070273
term: phosphatidylinositol-4-phosphate binding
ontology: MF
definition:
Binding to phosphatidylinositol-4-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' position.


go_id: GO:0070274
term: RES complex
ontology: CC
definition:
A protein complex that is required for efficient splicing, and prevents leakage of unspliced pre-mRNAs from the nucleus (named for pre-mRNA REtention and Splicing). In Saccharomyces, the complex consists of Ist3p, Bud13p, and Pml1p.


go_id: GO:0070275
term: aerobic ammonia oxidation to nitrite via pyruvic oxime
ontology: BP
definition:
The metabolic process in which ammonia (NH3) is oxidized to nitrite (NO2) in the presence of oxygen. Hydroxylamine is produced enzymatically, and, in the presence of pyruvate, forms pyruvic oxime in a spontaneous, non-enzymatic reaction; pyruvic oxime is then converted to nitrite.


go_id: GO:0070276
term: halogen metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving any halogen, elements of Group VII; includes metabolism of halogen-containing compounds.


go_id: GO:0070277
term: iodide oxidation
ontology: BP
definition:
The chemical reactions and pathways by which iodide is converted to diiodine, with the concomitant loss of electrons.


go_id: GO:0070278
term: extracellular matrix constituent secretion
ontology: BP
definition:
The controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell.


go_id: GO:0070279
term: vitamin B6 binding
ontology: MF
definition:
Binding to a vitamin B6 compound: pyridoxal, pyridoxamine, pyridoxine, or the active form, pyridoxal phosphate.


go_id: GO:0070280
term: pyridoxal binding
ontology: MF
definition:
Binding to pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carbaldehyde, a form of vitamin B6.


go_id: GO:0070281
term: pyridoxamine binding
ontology: MF
definition:
Binding to pyridoxamine, 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, a form of vitamin B6.


go_id: GO:0070284
term: 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity
ontology: MF
definition:
Catalysis of the reaction: 5-aminoimidazole ribonucleotide + S-adenosylmethionine = 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate + 5'deoxyadenosine.


go_id: GO:0070285
term: pigment cell development
ontology: BP
definition:
The process whose specific outcome is the progression of a pigment cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a pigment cell fate.


go_id: GO:0070286
term: axonemal dynein complex assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein complex, a dynein complex found in eukaryotic cilia and flagella, in which the motor domain heads interact with adjacent microtubules to generate a sliding force which is converted to a bending motion.


go_id: GO:0070288
term: ferritin complex
ontology: CC
definition:
A protein complex that binds iron and acts as a major iron storage system. Intracellular and extracellular ferritin complexes have different ratios of two types of ferritin monomer, the L (light) chain and H (heavy) chain.


go_id: GO:0070289
term: extracellular ferritin complex
ontology: CC
definition:
A ferritin complex located in the extracellular region. Extracellular ferritin complexes contain L (light) chains but few or no H (heavy) chains.


go_id: GO:0070290
term: N-acylphosphatidylethanolamine-specific phospholipase D activity
ontology: MF
definition:
Catalysis of the release of N-acylethanolamine from N-acyl-phosphatidylethanolamine (NAPE) to generate N-acylethanolamine (NAE).


go_id: GO:0070291
term: N-acylethanolamine metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving N-acylethanolamines. An N-acylethanolamine is an ethanolamine substituted at nitrogen by an acyl group.


go_id: GO:0070292
term: N-acylphosphatidylethanolamine metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving N-acylphosphatidylethanolamines. An N-acylphosphatidylethanolamine is a phosphatidylethanolamine substituted at nitrogen by an acyl group.


go_id: GO:0070293
term: renal absorption
ontology: BP
definition:
A renal system process in which water, ions, glucose and proteins are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures (e.g. protein absorption is observed in nephrocytes in Drosophila, see PMID:23264686).


go_id: GO:0070294
term: renal sodium ion absorption
ontology: BP
definition:
A renal system process in which sodium ions are taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.


go_id: GO:0070295
term: renal water absorption
ontology: BP
definition:
A renal system process in which water is taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.


go_id: GO:0070297
term: regulation of phosphorelay signal transduction system
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of signal transduction via a phosphorelay signal transduction system.


go_id: GO:0070298
term: negative regulation of phosphorelay signal transduction system
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction via a phosphorelay signal transduction system.


go_id: GO:0070299
term: positive regulation of phosphorelay signal transduction system
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of signal transduction via a phosphorelay signal transduction system.


go_id: GO:0070300
term: phosphatidic acid binding
ontology: MF
definition:
Binding to phosphatidic acid, any of a class of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids.


go_id: GO:0070301
term: cellular response to hydrogen peroxide
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.


go_id: GO:0070302
term: regulation of stress-activated protein kinase signaling cascade
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of signaling via a stress-activated protein kinase signaling cascade.


go_id: GO:0070303
term: negative regulation of stress-activated protein kinase signaling cascade
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of signaling via the stress-activated protein kinase signaling cascade.


go_id: GO:0070304
term: positive regulation of stress-activated protein kinase signaling cascade
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of signaling via the stress-activated protein kinase signaling cascade.


go_id: GO:0070305
term: response to cGMP
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cGMP (cyclic GMP, guanosine 3',5'-cyclophosphate) stimulus.


go_id: GO:0070306
term: lens fiber cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a lens fiber cell, any of the elongated, tightly packed cells that make up the bulk of the mature lens in the camera-type eye. The cytoplasm of a lens fiber cell is devoid of most intracellular organelles including the cell nucleus, and contains primarily crystallins, a group of water-soluble proteins expressed in vary large quantities.


go_id: GO:0070307
term: lens fiber cell development
ontology: BP
definition:
The process whose specific outcome is the progression of a lens fiber cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a lens fiber cell fate. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.


go_id: GO:0070308
term: lens fiber cell fate commitment
ontology: BP
definition:
The process in which the developmental fate of a cell becomes restricted such that it will develop into a lens fiber cell. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.


go_id: GO:0070309
term: lens fiber cell morphogenesis
ontology: BP
definition:
The process in which the structures of a lens fiber cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a lens fiber cell. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.


go_id: GO:0070310
term: ATR-ATRIP complex
ontology: CC
definition:
A protein complex that contains the protein kinase ATR and ATR-interacting protein (ATRIP) and binds single-stranded DNA; ssDNA binding affinity is increased in the presence of replication protein A.


go_id: GO:0070311
term: nucleosomal methylation activator complex
ontology: CC
definition:
A protein complex that contains eight subunits in common with the SWI/SNF complex, plus the ATPase BRG1 (SMARCA4) and the histone methyltransferase CARM1; the complex is involved in regulating nuclear receptor-dependent transcription.


go_id: GO:0070312
term: RAD52-ERCC4-ERCC1 complex
ontology: CC
definition:
A nucleotide-excision repair complex formed by the association of the heterodimeric endonuclease XPF/ERCC4-ERCC1 (Rad1p and Rad10p in S. cerevisiae) with the RAD52 protein.


go_id: GO:0070313
term: RGS6-DNMT1-DMAP1 complex
ontology: CC
definition:
A protein complex formed by the association of RGS6, a negative regulator of heterotrimeric G protein signaling, with the DMAP1-Dnmt1 transcriptional repressor complex; in the complex, RGS6 inhibits the transcriptional repressor activity of DMAP1.


go_id: GO:0070314
term: G1 to G0 transition
ontology: BP
definition:
A cell cycle arrest process that results in arrest during G1 phase, whereupon the cell enters a specialized resting state known as G0 or quiescence.


go_id: GO:0070315
term: G1 to G0 transition involved in cell differentiation
ontology: BP
definition:
A cell cycle arrest process that results in arrest during G1 phase, whereupon the cell enters G0 phase, in the context of cell differentiation.


go_id: GO:0070316
term: regulation of G0 to G1 transition
ontology: BP
definition:
A cell cycle process that modulates the rate or extent of the transition from the G0 quiescent state to the G1 phase.


go_id: GO:0070317
term: negative regulation of G0 to G1 transition
ontology: BP
definition:
A cell cycle process that stops, prevents, or reduces the rate or extent of the transition from the G0 quiescent state to the G1 phase.


go_id: GO:0070318
term: positive regulation of G0 to G1 transition
ontology: BP
definition:
A cell cycle process that activates or increases the rate or extent of the transition from the G0 quiescent state to the G1 phase.


go_id: GO:0070319
term: Golgi to plasma membrane transport vesicle
ontology: CC
definition:
A transport vesicle that mediates transport from the Golgi to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis.


go_id: GO:0070324
term: thyroid hormone binding
ontology: MF
definition:
Binding to thyroxine (T4) or triiodothyronine (T3), tyrosine-based hormones produced by the thyroid gland.


go_id: GO:0070327
term: thyroid hormone transport
ontology: BP
definition:
The directed movement of thyroid hormone into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0070328
term: triglyceride homeostasis
ontology: BP
definition:
Any process involved in the maintenance of an internal steady state of triglyceride within an organism or cell.


go_id: GO:0070331
term: CD20-Lck-Fyn complex
ontology: CC
definition:
A protein complex that contains the cell-surface protein CD20 and the Src family tyrosine kinases Lck and Fyn.


go_id: GO:0070332
term: CD20-Lck-Lyn-Fyn complex
ontology: CC
definition:
A protein complex that contains the cell-surface protein CD20 and the Src family tyrosine kinases Lck, Lyn and Fyn.


go_id: GO:0070333
term: alpha6-beta4 integrin-Shc-Grb2 complex
ontology: CC
definition:
A protein complex that consists of an alpha6-beta4 integrin complex bound to the adaptor proteins Shc and Grb2.


go_id: GO:0070335
term: aspartate binding
ontology: MF
definition:
Binding to aspartate, the alpha-amino-acid anion of 2-aminobutanedioic acid that has formula C4H5NO4.


go_id: GO:0070336
term: flap-structured DNA binding
ontology: MF
definition:
Binding to a flap structure in DNA. A DNA flap structure is one in which a single-stranded length of DNA or RNA protrudes from a double-stranded DNA molecule.


go_id: GO:0070337
term: 3'-flap-structured DNA binding
ontology: MF
definition:
Binding to a 3'-flap structure in DNA. A DNA flap structure is one in which a single-stranded 3'-end of DNA or RNA protrudes from a double-stranded DNA molecule.


go_id: GO:0070338
term: 5'-flap-structured DNA binding
ontology: MF
definition:
Binding to a 5'-flap structure in DNA. A DNA flap structure is one in which a single-stranded 5'-end of DNA or RNA protrudes from a double-stranded DNA molecule. 5'-flap structures can be formed during DNA repair or lagging strand synthesis; in the latter case RNA flaps form from lagging strand RNA primers.


go_id: GO:0070339
term: response to bacterial lipopeptide
ontology: BP
definition:
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipopeptide stimulus.


go_id: GO:0070340
term: detection of bacterial lipopeptide
ontology: BP
definition:
The series of events in which a bacterial lipopeptide stimulus is received by a cell and converted into a molecular signal.


go_id: GO:0070341
term: fat cell proliferation
ontology: BP
definition:
The multiplication or reproduction of fat cells by cell division, resulting in the expansion of their population. A fat cell is an animal connective tissue cell specialized for the synthesis and storage of fat.


go_id: GO:0070342
term: brown fat cell proliferation
ontology: BP
definition:
The multiplication or reproduction of brown fat cells by cell division, resulting in the expansion of their population. A brown fat cell is a fat cell found the thermogenic form of adipose tissue found in newborns of many species.


go_id: GO:0070343
term: white fat cell proliferation
ontology: BP
definition:
The multiplication or reproduction of white fat cells by cell division, resulting in the expansion of their population.


go_id: GO:0070353
term: GATA1-TAL1-TCF3-Lmo2 complex
ontology: CC
definition:
A protein complex that contains the zinc finger transcription factor GATA1, the LIM domain protein Lmo2 (RBTN2), the basic helix-loop-helix protein TAL1 and its binding partner TCF3. The complex is involved transcriptional regulation in hematopoiesis.


go_id: GO:0070354
term: GATA2-TAL1-TCF3-Lmo2 complex
ontology: CC
definition:
A protein complex that contains the zinc finger transcription factor GATA2, the LIM domain protein Lmo2 (RBTN2), the basic helix-loop-helix protein TAL1 and its binding partner TCF3. The complex is involved transcriptional regulation in hematopoiesis.


go_id: GO:0070355
term: synaptotagmin-synaptobrevin 2-SNAP-25-syntaxin-1a-syntaxin-1b-Rab3a-complexin II complex
ontology: CC
definition:
A SNARE complex that contains synaptotagmin, synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, syntaxin1b, Rab3a, and complexin II (or orthologs thereof).


go_id: GO:0070356
term: synaptotagmin-synaptobrevin 2-SNAP-25-syntaxin-1a-syntaxin-1b-Rab3a complex
ontology: CC
definition:
A SNARE complex that contains synaptotagmin, synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, syntaxin1b, and Rab3a (or orthologs thereof).


go_id: GO:0070357
term: alphav-beta3 integrin-CD47 complex
ontology: CC
definition:
A protein complex that consists of an alphav-beta3 integrin complex bound to CD47 (also known as IAP).


go_id: GO:0070358
term: actin polymerization-dependent cell motility
ontology: BP
definition:
A process involved in the controlled movement of a bacterial cell powered by the continuous polymerization of actin at one pole of the cell.


go_id: GO:0070360
term: actin polymerization-dependent cell migration in host
ontology: BP
definition:
The directional movement of an organism, usually a bacterial cell, from one place to another within its host organism, by a process involving continuous polymerization of actin at one pole of the symbiont cell. Some bacteria use host actin for migration. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0070365
term: hepatocyte differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires the specialized features of a hepatocyte. A hepatocyte is specialized epithelial cell that is organized into interconnected plates called lobules, and is the main structural component of the liver.


go_id: GO:0070369
term: beta-catenin-TCF7L2 complex
ontology: CC
definition:
A protein complex that contains beta-catenin and TCF7L2 (TCF4), binds to the TCF DNA motif within a promoter element, and is involved in the regulation of WNT target gene transcription.


go_id: GO:0070371
term: ERK1 and ERK2 cascade
ontology: BP
definition:
An intracellular protein kinase cascade containing at least ERK1 or ERK2 (MAPKs), a MEK (a MAPKK) and a MAP3K. The cascade may involve 4 different kinases, as it can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell.


go_id: GO:0070372
term: regulation of ERK1 and ERK2 cascade
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.


go_id: GO:0070373
term: negative regulation of ERK1 and ERK2 cascade
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.


go_id: GO:0070374
term: positive regulation of ERK1 and ERK2 cascade
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.


go_id: GO:0070375
term: ERK5 cascade
ontology: BP
definition:
An intracellular protein kinase cascade containing at least ERK5 (also called BMK1; a MAPK), a MEK (a MAPKK) and a MAP3K. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell.


go_id: GO:0070376
term: regulation of ERK5 cascade
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of signal transduction mediated by the ERK5 cascade.


go_id: GO:0070377
term: negative regulation of ERK5 cascade
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK5 cascade.


go_id: GO:0070378
term: positive regulation of ERK5 cascade
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK5 cascade.


go_id: GO:0070380
term: high mobility group box 1 receptor activity
ontology: MF
definition:
Combining with high mobility group box 1 (HMBGB1) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


go_id: GO:0070381
term: endosome to plasma membrane transport vesicle
ontology: CC
definition:
A transport vesicle that mediates transport from the endosome to the plasma membrane, and fuses with the plasma membrane to deliver lipids and membrane proteins to the plasma membrane  and to release various cargo molecules, such as proteins or hormones, by exocytosis.


go_id: GO:0070382
term: exocytic vesicle
ontology: CC
definition:
A transport vesicle that mediates transport from an intracellular compartment to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis.


go_id: GO:0070384
term: Harderian gland development
ontology: BP
definition:
The process whose specific outcome is the progression of the Harderian gland over time, from its formation to the mature structure. The Harderian gland is an anterior orbital structure usually associated with the nictitating membrane, and produces and secretes a variety of substances to the eye, depending upon the species.


go_id: GO:0070385
term: egasyn-beta-glucuronidase complex
ontology: CC
definition:
A protein complex that contains beta-glucuronidase and the carboxyl esterase egasyn; formation of the complex causes beta-glucuronidase to be retained in the endoplasmic reticulum.


go_id: GO:0070386
term: procollagen-proline 4-dioxygenase complex, alpha(I) type
ontology: CC
definition:
A procollagen-proline 4-dioxygenase complex that contains alpha subunits of the type I isoform; its activity is readily inhibited by poly(L-proline).


go_id: GO:0070387
term: procollagen-proline 4-dioxygenase complex, alpha(II) type
ontology: CC
definition:
A procollagen-proline 4-dioxygenase complex that contains alpha subunits of the type II isoform; its activity is inhibited by poly(L-proline) only at high concentrations.


go_id: GO:0070390
term: transcription export complex 2
ontology: CC
definition:
A protein complex that couples SAGA-dependent gene expression to mRNA export at the inner side of the nuclear pore complex (NPC). The TREX-2 complex is tethered to the inner side of the NPC via the nucleoporins Nup1 and Nup60; in S. cerevisiae it contains Sac3p, Thp1p, Sem1, Sus1p and Cdc31p.


go_id: GO:0070391
term: response to lipoteichoic acid
ontology: BP
definition:
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoteichoic acid stimulus; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.


go_id: GO:0070392
term: detection of lipoteichoic acid
ontology: BP
definition:
The series of events in which a lipoteichoic acid stimulus is received by a cell and converted into a molecular signal; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.


go_id: GO:0070393
term: teichoic acid catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues.


go_id: GO:0070394
term: lipoteichoic acid metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.


go_id: GO:0070395
term: lipoteichoic acid biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.


go_id: GO:0070396
term: lipoteichoic acid catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.


go_id: GO:0070397
term: wall teichoic acid metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan.


go_id: GO:0070398
term: wall teichoic acid biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan.


go_id: GO:0070399
term: wall teichoic acid catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan.


go_id: GO:0070400
term: teichoic acid D-alanylation
ontology: BP
definition:
The formation of a D-alanyl ester of teichoic acid. Alanylation of teichoic acids modulates the properties of the bacterial cell wall and modulates the inflammatory properties of the teichoic acid.


go_id: GO:0070401
term: NADP+ binding
ontology: MF
definition:
Binding to the oxidized form, NADP+, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.


go_id: GO:0070402
term: NADPH binding
ontology: MF
definition:
Binding to the reduced form, NADPH, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.


go_id: GO:0070403
term: NAD+ binding
ontology: MF
definition:
Binding to the oxidized form, NAD, of nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions.


go_id: GO:0070404
term: NADH binding
ontology: MF
definition:
Binding to the reduced form, NADH, of nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions.


go_id: GO:0070407
term: oxidation-dependent protein catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the oxidation of one or more amino acid residues in the protein.


go_id: GO:0070408
term: carbamoyl phosphate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving carbamoyl phosphate, an intermediate in the urea cycle and other nitrogen compound metabolic pathways.


go_id: GO:0070409
term: carbamoyl phosphate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of carbamoyl phosphate, an intermediate in the urea cycle and other nitrogen compound metabolic pathways.


go_id: GO:0070413
term: trehalose metabolism in response to stress
ontology: BP
definition:
The chemical reactions and pathways involving trehalose that occur as a result of a stimulus indicating the organism is under stress.


go_id: GO:0070414
term: trehalose metabolism in response to heat stress
ontology: BP
definition:
The chemical reactions and pathways involving trehalose that occur as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.


go_id: GO:0070415
term: trehalose metabolism in response to cold stress
ontology: BP
definition:
The chemical reactions and pathways involving trehalose that occur as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.


go_id: GO:0070416
term: trehalose metabolism in response to water deprivation
ontology: BP
definition:
The chemical reactions and pathways involving trehalose that occur as a result of deprivation of water.


go_id: GO:0070417
term: cellular response to cold
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.


go_id: GO:0070418
term: DNA-dependent protein kinase complex
ontology: CC
definition:
A protein complex that is involved in the repair of DNA double-strand breaks and, in mammals, V(D)J recombination events. It consists of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs) and the DNA end-binding heterodimer Ku.


go_id: GO:0070419
term: nonhomologous end joining complex
ontology: CC
definition:
A protein complex that plays a role in DNA double-strand break repair via nonhomologous end joining. Such complexes typically contain a specialized DNA ligase (e.g. Lig4 in eukaryotes) and one or more proteins that bind to DNA ends.


go_id: GO:0070420
term: Ku-DNA ligase complex
ontology: CC
definition:
A nonhomologous end joining complex that contains one or more Ku monomers and one or more DNA ligase molecules from the LigC or LigD family, and mediates nonhomologous end joining in bacteria.


go_id: GO:0070422
term: G-protein beta/gamma-Raf-1 complex
ontology: CC
definition:
A protein complex formed by the association of the serine-threonine protein kinase Raf-1 with the beta and gamma subunits of a heterotrimeric G protein.


go_id: GO:0070423
term: nucleotide-binding oligomerization domain containing signaling pathway
ontology: BP
definition:
The series of molecular signals initiated by the binding of a ligand (such as a bacterial peptidoglycan) to a cytoplasmic nucleotide-binding oligomerization domain containing (NOD) protein receptor, and ending with regulation of a downstream cellular process.


go_id: GO:0070424
term: regulation of nucleotide-binding oligomerization domain containing signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of a nucleotide-binding oligomerization domain containing (NOD) pathway.


go_id: GO:0070425
term: negative regulation of nucleotide-binding oligomerization domain containing signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing (NOD) pathway.


go_id: GO:0070426
term: positive regulation of nucleotide-binding oligomerization domain containing signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing (NOD) pathway.


go_id: GO:0070427
term: nucleotide-binding oligomerization domain containing 1 signaling pathway
ontology: BP
definition:
The series of molecular signals initiated by the binding of a ligand (such as a bacterial peptidoglycan) to a cytoplasmic nucleotide-binding oligomerization domain containing 1 (NOD1) protein receptor, and ending with regulation of a downstream cellular process.


go_id: GO:0070428
term: regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway.


go_id: GO:0070429
term: negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway.


go_id: GO:0070430
term: positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway.


go_id: GO:0070431
term: nucleotide-binding oligomerization domain containing 2 signaling pathway
ontology: BP
definition:
The series of molecular signals initiated by the binding of a ligand (such as a bacterial peptidoglycan) to a cytoplasmic nucleotide-binding oligomerization domain containing 2 (NOD2) protein receptor, and ending with regulation of a downstream cellular process.


go_id: GO:0070432
term: regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway.


go_id: GO:0070433
term: negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway.


go_id: GO:0070434
term: positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway.


go_id: GO:0070435
term: Shc-EGFR complex
ontology: CC
definition:
A protein complex that contains the epidermal growth factor receptor (EGFR) and the adaptor protein Shc, and is involved in linking EGFR activation to the p21-Ras pathway.


go_id: GO:0070436
term: Grb2-EGFR complex
ontology: CC
definition:
A protein complex that contains the epidermal growth factor receptor (EGFR) and Grb2, and is involved in linking EGFR activation to the p21-Ras pathway.


go_id: GO:0070437
term: Grb2-Shc complex
ontology: CC
definition:
A protein complex that contains Grb2 and the adaptor protein Shc, and is involved in linking epidermal growth factor receptor (EGFR) activation to the p21-Ras pathway.


go_id: GO:0070439
term: Mad-Max-mSin3A complex
ontology: CC
definition:
A transcriptional repressor complex that contains a heterodimer of the bHLH-ZIP proteins Mad and Max, plus mSin3A, a homolog of the yeast Sin3p.


go_id: GO:0070440
term: Mad-Max-mSin3B complex
ontology: CC
definition:
A transcriptional repressor complex that contains a heterodimer of the bHLH-ZIP proteins Mad and Max, plus mSin3B, a homolog of the yeast Sin3p.


go_id: GO:0070441
term: G-protein beta/gamma-Btk complex
ontology: CC
definition:
A protein complex formed by the association of the Bruton tyrosine protein kinase Btk, which is implicated in mammalian X-linked immunodeficiencies, with the beta and gamma subunits of a heterotrimeric G protein.


go_id: GO:0070443
term: Mad-Max complex
ontology: CC
definition:
A transcriptional repressor complex that consists of a heterodimer of the bHLH-ZIP proteins Mad and Max.


go_id: GO:0070444
term: oligodendrocyte progenitor proliferation
ontology: BP
definition:
The multiplication or reproduction of oligodendrocyte progenitor cells by cell division, resulting in the expansion of their population. Oligodendrocyte progenitors give rise to oligodendrocytes, which form the insulating myelin sheath of axons in the central nervous system.


go_id: GO:0070445
term: regulation of oligodendrocyte progenitor proliferation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of oligodendrocyte progenitor proliferation.


go_id: GO:0070447
term: positive regulation of oligodendrocyte progenitor proliferation
ontology: BP
definition:
Any process that activates or increases the rate or extent of oligodendrocyte progenitor proliferation.


go_id: GO:0070448
term: laricitrin 5'-O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + laricitrin = S-adenosyl-L-homocysteine + syringetin.


go_id: GO:0070449
term: elongin complex
ontology: CC
definition:
A transcription elongation factor complex that suppresses RNA polymerase II pausing, and may act by promoting proper alignment of the 3'-end of nascent transcripts with the polymerase catalytic site. Consists of a transcriptionally active Elongin A subunit (about 100 kDa) and two smaller Elongin B (about 18 kDa) and Elongin C (about 15 kDa) subunits.


go_id: GO:0070450
term: interleukin4-interleukin-4 receptor complex
ontology: CC
definition:
A protein complex that is formed by the association of a heterodimeric interleukin-4 receptor complex with an interleukin-4 molecule.


go_id: GO:0070451
term: cell hair
ontology: CC
definition:
A long, thin cell projection that contains F-actin and tubulin, with microtubules centrally located and F-actin peripherally located.


go_id: GO:0070452
term: positive regulation of ergosterol biosynthetic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ergosterol.


go_id: GO:0070453
term: regulation of heme biosynthetic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme.


go_id: GO:0070454
term: negative regulation of heme biosynthetic process
ontology: BP
definition:
Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme.


go_id: GO:0070455
term: positive regulation of heme biosynthetic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme.


go_id: GO:0070458
term: cellular detoxification of nitrogen compound
ontology: BP
definition:
Any cellular process that reduces or removes the toxicity of nitrogenous compounds which are dangerous or toxic. This includes the aerobic conversion of toxic compounds to harmless substances.


go_id: GO:0070459
term: prolactin secretion
ontology: BP
definition:
The regulated release of prolactin, a peptide hormone that stimulates lactation, from secretory granules in the anterior pituitary.


go_id: GO:0070460
term: thyroid-stimulating hormone secretion
ontology: BP
definition:
The regulated release of thyroid-stimulating hormone, a peptide hormone that stimulates the activity of the thyroid gland, from secretory granules in the anterior pituitary.


go_id: GO:0070461
term: SAGA-type complex
ontology: CC
definition:
A histone acetyltransferase complex that acetylates nucleosomal histones H2B, H3, or H4 and is required for the expression of a subset of Pol II-transcribed genes. This complex includes the acetyltransferases GCN5/KAT2A or PCAF/KAT2B, several proteins of the ADA, SGF and SPT families, and several TBP-associate proteins (TAFs).


go_id: GO:0070463
term: tubulin-dependent ATPase activity
ontology: MF
definition:
Catalysis of the reaction: ATP + H2O = ADP + phosphate. This reaction requires the presence of a tubulin dimer to accelerate release of ADP and phosphate.


go_id: GO:0070464
term: alphav-beta3 integrin-collagen alpha3(VI) complex
ontology: CC
definition:
A protein complex that consists of an alphav-beta3 integrin complex bound to the alpha3 chain of type VI collagen; the integrin binds most strongly to unfolded collagen.


go_id: GO:0070465
term: alpha1-beta1 integrin-alpha3(VI) complex
ontology: CC
definition:
A protein complex that consists of an alpha1-beta1 integrin complex bound to a type VI collagen triple helix containing an alpha3(VI) chain.


go_id: GO:0070466
term: alpha2-beta1 integrin-alpha3(VI) complex
ontology: CC
definition:
A protein complex that consists of an alpha2-beta1 integrin complex bound to a type VI collagen triple helix containing an alpha3(VI) chain.


go_id: GO:0070467
term: RC-1 DNA recombination complex
ontology: CC
definition:
A protein complex that contains DNA ligase III, DNA polymerase epsilon, a 5'-3' exonuclease, and the SMC1 and SMC2 proteins, and is involved in recombinational repair of deletions and gaps in DNA.


go_id: GO:0070468
term: dentin extracellular matrix secretion
ontology: BP
definition:
The regulated release by odontoblasts of the extracellular matrix constituents, including collagen, that form the basis of dentin.


go_id: GO:0070469
term: respirasome
ontology: CC
definition:
The protein complexes that form the electron transport system (the respiratory chain), associated with a cell membrane, usually the plasma membrane (in prokaryotes) or the inner mitochondrial membrane (on eukaryotes). The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient.


go_id: GO:0070470
term: plasma membrane respirasome
ontology: CC
definition:
A respiratory chain located in the plasma membrane of a cell; made up of the protein complexes that form the electron transport system (the respiratory chain), associated with the plasma membrane. The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient.


go_id: GO:0070471
term: uterine smooth muscle contraction
ontology: BP
definition:
A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the uterus. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The uterus is a muscular organ of the female mammal for containing and usually for nourishing the young during development prior to birth.


go_id: GO:0070475
term: rRNA base methylation
ontology: BP
definition:
The addition of a methyl group to an atom in the nucleoside base portion of a nucleotide residue in an rRNA molecule.


go_id: GO:0070476
term: rRNA (guanine-N7)-methylation
ontology: BP
definition:
The addition of a methyl group to the N7 atom in the base portion of a guanine nucleotide residue in an rRNA molecule.


go_id: GO:0070477
term: endospore core
ontology: CC
definition:
An intracellular part that represents the innermost portion of an endospore; the endospore core is dehydrated, enriched in dipicolinic acid and divalent cations, and metabolically inactive.


go_id: GO:0070478
term: nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of the nuclear-transcribed mRNA transcript body of an mRNA in which an amino-acid codon has changed to a nonsense codon; occurs when the 3' end is not protected by a 3'-poly(A) tail; degradation proceeds in the 3' to 5' direction.


go_id: GO:0070479
term: nuclear-transcribed mRNA catabolic process, 5'-3' exonucleolytic nonsense-mediated decay
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of the nuclear-transcribed mRNA transcript body of an mRNA in which an amino-acid codon has changed to a nonsense codon; occurs when the 5' end is not protected by a 5'-cap; degradation proceeds in the 5' to 3' direction.


go_id: GO:0070480
ontology: BP
term:
exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-independent decay

definition:
The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs independent of deadenylation, but requires decapping followed by transcript decay.


go_id: GO:0070481
term: nuclear-transcribed mRNA catabolic process, non-stop decay
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that is lacking a stop codon.


go_id: GO:0070482
term: response to oxygen levels
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen.


go_id: GO:0070483
term: detection of hypoxia
ontology: BP
definition:
The series of events in which a stimulus indicating lowered oxygen tension is received by a cell and converted into a molecular signal. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.


go_id: GO:0070484
term: dehydro-D-arabinono-1,4-lactone metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving dehydro-D-arabinono-1,4-lactone, the gamma-lactone (5R)-3,4-dihydroxy-5-(hydroxymethyl)furan-2(5H)-one.


go_id: GO:0070485
term: dehydro-D-arabinono-1,4-lactone biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of dehydro-D-arabinono-1,4-lactone, the gamma-lactone (5R)-3,4-dihydroxy-5-(hydroxymethyl)furan-2(5H)-one.


go_id: GO:0070490
term: protein pupylation
ontology: BP
definition:
The process in which a Pup protein is conjugated to a target protein via an isopeptide bond between the carboxy-terminus of Pup and the epsilon-amino group of a lysine residue of the target protein.


go_id: GO:0070492
term: oligosaccharide binding
ontology: MF
definition:
Binding to an oligosaccharide, a molecule with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.


go_id: GO:0070493
term: thrombin-activated receptor signaling pathway
ontology: BP
definition:
A G protein-coupled receptor signaling pathway initiated by thrombin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.


go_id: GO:0070494
term: regulation of thrombin-activated receptor signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of a thrombin-activated receptor signaling pathway activity. A thrombin receptor signaling pathway is the series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands.


go_id: GO:0070495
term: negative regulation of thrombin-activated receptor signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of thrombin-activated receptor protein signaling pathway activity. A thrombin receptor signaling pathway is the series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands.


go_id: GO:0070496
term: positive regulation of thrombin-activated receptor signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of thrombin-activated receptor protein signaling pathway activity. A thrombin receptor signaling pathway is the series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands.


go_id: GO:0070497
term: 6-carboxy-5,6,7,8-tetrahydropterin synthase activity
ontology: MF
definition:
Catalysis of the reaction: 7,8-dihydroneopterin triphosphate + H2O = 6-carboxy-5,6,7,8-tetrahydropterin + triphosphate + acetaldehyde + 2 H+.


go_id: GO:0070498
term: interleukin-1-mediated signaling pathway
ontology: BP
definition:
The series of molecular signals initiated by interleukin-1 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


go_id: GO:0070499
term: exosporium assembly
ontology: BP
definition:
A process that is carried out at the cellular level which results in the formation of an exosporium, the outermost layer of a bacterial endospore.


go_id: GO:0070500
term: poly-gamma-glutamate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving poly-gamma-glutamate, a polymer of D- and/or L-glutamic acid residues linked by gamma-peptidyl bonds.


go_id: GO:0070501
term: poly-gamma-glutamate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of poly-gamma-glutamate, a polymer of D- and/or L-glutamic acid residues linked by gamma-peptidyl bonds.


go_id: GO:0070502
term: capsule poly-gamma-glutamate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of poly-gamma-glutamate, a polymer of D- and/or L-glutamic acid residues linked by gamma-peptidyl bonds, that forms all or part of a bacterial capsule.


go_id: GO:0070503
term: selenium-containing prosthetic group metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving a prosthetic group that contains selenium, as in the selenium-dependent molybdenum hydroxylases. The selenium atom in the prosthetic group is required for enzymatic function but is labile to a variety of treatments.


go_id: GO:0070504
term: selenium-containing prosthetic group biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a prosthetic group that contains selenium, as in the selenium-dependent molybdenum hydroxylases. The selenium atom in the prosthetic group is required for enzymatic function but is labile to a variety of treatments.


go_id: GO:0070505
term: pollen coat
ontology: CC
definition:
A layer of extracellular matrix deposited onto the surface of the pollen wall upon disintegration of the tapetal layer of the anther wall in the late stages of pollen development. The composition of this material is highly heterogeneous and includes waxes, lipid droplets, small aromatic molecules, and proteins. The pollen coat is proposed to have many functions, such as holding pollen in the anther until dispersal, facilitation of pollen dispersal, protection of pollen from water loss and UV radiation, and facilitation of adhesion of pollen to the stigma.


go_id: GO:0070506
term: high-density lipoprotein particle receptor activity
ontology: MF
definition:
Combining with a high-density lipoprotein particle and delivering the high-density lipoprotein into the cell via endocytosis.


go_id: GO:0070507
term: regulation of microtubule cytoskeleton organization
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.


go_id: GO:0070510
term: regulation of histone H4-K20 methylation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 20 of histone H4.


go_id: GO:0070511
term: negative regulation of histone H4-K20 methylation
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 20 of histone H4.


go_id: GO:0070512
term: positive regulation of histone H4-K20 methylation
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 20 of histone H4.


go_id: GO:0070513
term: death domain binding
ontology: MF
definition:
Binding to a death domain of a protein. The death domain (DD) is a homotypic protein interaction module composed of a bundle of six alpha-helices. DD bind each other forming oligomers. Some DD-containing proteins are involved in the regulation of apoptosis and inflammation through their activation of caspases and NF-kappaB.


go_id: GO:0070514
term: SRF-myogenin-E12 complex
ontology: CC
definition:
A transcription factor complex that contains the serum response factor (SRF) and the basic helix-loop-helix proteins myogenin and E12, and is involved in activating transcription of muscle-specific genes.


go_id: GO:0070516
term: CAK-ERCC2 complex
ontology: CC
definition:
A protein complex formed by the association of the cyclin-dependent protein kinase activating kinase (CAK) holoenzyme complex with ERCC2.


go_id: GO:0070517
term: DNA replication factor C core complex
ontology: CC
definition:
A protein complex containing three of the five subunits of eukaryotic replication factor C, those corresponding to human p40, p38, and p37.


go_id: GO:0070518
term: alpha4-beta1 integrin-CD53 complex
ontology: CC
definition:
A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD53, a member of the tetraspan family.


go_id: GO:0070519
term: alpha4-beta1 integrin-CD63 complex
ontology: CC
definition:
A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD63, a member of the tetraspan family.


go_id: GO:0070520
term: alpha4-beta1 integrin-CD81 complex
ontology: CC
definition:
A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD81, a member of the tetraspan family.


go_id: GO:0070521
term: alpha4-beta1 integrin-CD82 complex
ontology: CC
definition:
A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD82, a member of the tetraspan family.


go_id: GO:0070522
term: ERCC4-ERCC1 complex
ontology: CC
definition:
A heterodimeric nucleotide-excision repair complex that has endonuclease activity specific for bubble structures characteristic of certain DNA lesions. The subunits are known as XPF/ERCC4 and ERCC1 in mammals, and Rad1p and Rad10p in S. cerevisiae.


go_id: GO:0070525
term: tRNA threonylcarbamoyladenosine metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving tRNA threonylcarbamoyladenosine, a modified nucleoside found in some tRNA molecules.


go_id: GO:0070528
term: protein kinase C signaling
ontology: BP
definition:
A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.


go_id: GO:0070530
term: K63-linked polyubiquitin modification-dependent protein binding
ontology: MF
definition:
Binding to a protein upon poly-ubiquitination formed by linkages between lysine residues at position 63 in the target protein.


go_id: GO:0070531
term: BRCA1-A complex
ontology: CC
definition:
A protein complex that contains the BRCA1-BARD1 heterodimer, RAP80/UIMC1, BRCC3/BRCC36, BRE/BRCC45, FAM175A/CCDC98/Abraxas and MERIT40/NBA1, and specifically recognizes and binds K63-linked polyubiquitin chains present on histone H2A and H2AX at DNA damage sites.


go_id: GO:0070532
term: BRCA1-B complex
ontology: CC
definition:
A protein complex that contains the BRCA1-BARD1 heterodimer, BACH1 and TopBP1, and binds to DNA during S phase at DNA damage sites.


go_id: GO:0070533
term: BRCA1-C complex
ontology: CC
definition:
A protein complex that contains the BRCA1-BARD1 heterodimer, CtIP and Mre11/Rad50/NBS1 (M/R/N) complex, and binds to DNA at DNA damage sites. BRCA1-C binding ta damaged DNA is required for DNA damage-induced Chk1 phosphorylation and the G2/M transition checkpoint.


go_id: GO:0070534
term: protein K63-linked ubiquitination
ontology: BP
definition:
A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a protein. K63-linked ubiquitination does not target the substrate protein for degradation, but is involved in several pathways, notably as a signal to promote error-free DNA postreplication repair.


go_id: GO:0070535
term: histone H2A K63-linked ubiquitination
ontology: BP
definition:
A histone ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a lysine residue in histone H2A or the variant H2AX.


go_id: GO:0070536
term: protein K63-linked deubiquitination
ontology: BP
definition:
A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a protein.


go_id: GO:0070537
term: histone H2A K63-linked deubiquitination
ontology: BP
definition:
A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a lysine residue in histone H2A or the variant H2AX.


go_id: GO:0070541
term: response to platinum ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platinum stimulus.


go_id: GO:0070542
term: response to fatty acid
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus.


go_id: GO:0070543
term: response to linoleic acid
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a linoleic acid stimulus.


go_id: GO:0070544
term: histone H3-K36 demethylation
ontology: BP
definition:
The modification of histone H3 by the removal of a methyl group from lysine at position 36 of the histone.


go_id: GO:0070545
term: PeBoW complex
ontology: CC
definition:
A protein complex that is involved in coordinating ribosome biogenesis with cell cycle progression. In human, it is composed of Pes1, Bop1, and WDR12; in Saccharomyces the proteins are known as Nop7p, Erb1 and Ytm1 respectively.


go_id: GO:0070546
term: L-phenylalanine aminotransferase activity
ontology: MF
definition:
Catalysis of the transfer of an amino group from L-phenylalanine to an acceptor, usually a 2-oxo acid.


go_id: GO:0070549
term: siRNA-mediated gene silencing by inhibition of translation
ontology: BP
definition:
An siRNA-mediated post-transcriptional gene silencing pathway that blocks the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), an siRNA will typically mediate repression of translation if the siRNA perfectly complements elements located in the 3' untranslated region of target mRNAs.


go_id: GO:0070550
term: rDNA chromatin condensation
ontology: BP
definition:
The process in which the chromatin structure of the rDNA repeats is compacted. In S. cerevisiae, condensation and resolution of the rDNA occurs during anaphase.


go_id: GO:0070551
term: endoribonuclease activity, cleaving siRNA-paired mRNA
ontology: MF
definition:
Catalysis of the endonucleolytic cleavage of the mRNA in a double-stranded RNA molecule formed by the base pairing of an mRNA with an siRNA, yielding 5'-phosphomonoesters.


go_id: GO:0070552
term: BRISC complex
ontology: CC
definition:
A protein complex that contains the FAM175B/ABRO1, BRCC3/BRCC36, BRE/BRCC45 and MERIT40/NBA1 proteins, and specifically cleaves K63-linked polyubiquitin chains.


go_id: GO:0070554
term: synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex
ontology: CC
definition:
A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 3, and a complexin (or orthologs thereof).


go_id: GO:0070555
term: response to interleukin-1
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus.


go_id: GO:0070556
term: TAF4B-containing transcription factor TFIID complex
ontology: CC
definition:
A transcription factor TFIID complex that contains the TBP-associated factor TAF4B (also known as TAFII105 in human), a cell-type-specific variant of TAF4.


go_id: GO:0070557
term: PCNA-p21 complex
ontology: CC
definition:
A protein complex that contains the cyclin-dependent protein kinase inhibitor p21WAF1/CIP1 bound to PCNA; formation of the complex inhibits DNA replication.


go_id: GO:0070558
term: alphaM-beta2 integrin-CD63 complex
ontology: CC
definition:
A protein complex that consists of an alphaM-beta2 integrin complex bound to membrane protein CD63, a member of the tetraspan family.


go_id: GO:0070559
term: lysosomal multienzyme complex
ontology: CC
definition:
A protein complex found in the lysosome that contains beta-galactosidase, cathepsin A, alpha-neuraminidase and N-acetylgalactosamine-6-sulfate sulfatase, and is involved in glycosaminoglycan catabolism.


go_id: GO:0070561
term: vitamin D receptor signaling pathway
ontology: BP
definition:
The series of molecular signals generated as a consequence of a vitamin D receptor binding to one of its physiological ligands.


go_id: GO:0070562
term: regulation of vitamin D receptor signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of vitamin D receptor signaling pathway activity.


go_id: GO:0070563
term: negative regulation of vitamin D receptor signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the vitamin D receptor signaling pathway activity.


go_id: GO:0070564
term: positive regulation of vitamin D receptor signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of vitamin D receptor signaling pathway activity.


go_id: GO:0070565
term: telomere-telomerase complex
ontology: CC
definition:
A complex of DNA and protein located at the end of a linear chromosome that enables replication of the telomeric repeat sequences at the end of a linear chromosome.


go_id: GO:0070570
term: regulation of neuron projection regeneration
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage.


go_id: GO:0070571
term: negative regulation of neuron projection regeneration
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage.


go_id: GO:0070572
term: positive regulation of neuron projection regeneration
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage.


go_id: GO:0070573
term: metallodipeptidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of a dipeptide by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.


go_id: GO:0070574
term: cadmium ion transmembrane transport
ontology: BP
definition:
A process in which a cadmium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.


go_id: GO:0070575
ontology: BP
term:
peptide mating pheromone maturation involved in regulation of pheromone-induced unidirectional conjugation

definition:
The formation of a mature peptide mating pheromone by proteolysis and/or modification of a peptide precursor, occurring in the context of pheromone-induced unidirectional conjugation.


go_id: GO:0070578
term: RISC-loading complex
ontology: CC
definition:
A trimeric protein complex required for the formation of a mature RNA-induced silencing complex (RISC). In humans the complex is composed of the endonuclease Dicer (DICER1), TRBP (TARBP2) and the Argonaute protein Ago2 (EIF2C2/AGO2). Within the complex, Dicer and TRBP are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto Ago2. Ago2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from Dicer and TRBP. This complex has endoribonuclease activity.


go_id: GO:0070579
term: methylcytosine dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: methylcytosine + 2-oxoglutarate + O2 = 5-hydroxymethylcytosine + succinate + CO2.


go_id: GO:0070580
term: base J metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving base J (beta-D-glucosyl-hydroxymethyluracil), a hypermodified thymidine residue found in the genome of kinetoplastid parasites. This modified base is localized primarily to repetitive DNA, namely the telomeres, and is implicated in the regulation of antigenic variation. The base is synthesized in a two-step pathway. Initially, a thymidine residue in DNA is hydroxylated by a thymidine hydroxylase (TH) to form the intermediate hydroxymethyluracil, which is then glucosylated to form base J.


go_id: GO:0070581
term: rolling circle DNA replication
ontology: BP
definition:
A DNA-dependent DNA replication process in which a single-stranded DNA molecule is synthesized from a circular duplex template. Replication typically does not cease when one circumference has been replicated, but continues around the circumference several more times, producing a long single strand comprising multimers of the replicon.


go_id: GO:0070582
term: theta DNA replication
ontology: BP
definition:
A DNA-dependent DNA replication process in which a double-stranded DNA molecule is synthesized from a circular duplex template.


go_id: GO:0070583
term: spore membrane bending pathway
ontology: BP
definition:
The process in which a bending force is generated in the prospore membrane to form the characteristic curved shape of the prospore.


go_id: GO:0070585
term: protein localization to mitochondrion
ontology: BP
definition:
A process in which a protein is transported to, or maintained in, a location within the mitochondrion.


go_id: GO:0070587
term: regulation of cell-cell adhesion involved in gastrulation
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of attachment of a cell to another cell affecting gastrulation.


go_id: GO:0070588
term: calcium ion transmembrane transport
ontology: BP
definition:
A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.


go_id: GO:0070589
term: cellular component macromolecule biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a macromolecule that is destined to form part of a specific cellular component.


go_id: GO:0070590
term: spore wall biogenesis
ontology: BP
definition:
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a spore wall. A spore wall is the specialized cell wall lying outside the cell membrane of a spore.


go_id: GO:0070591
term: ascospore wall biogenesis
ontology: BP
definition:
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of an ascospore wall.


go_id: GO:0070592
term: cell wall polysaccharide biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a polysaccharide destined to form part of a cell wall.


go_id: GO:0070593
term: dendrite self-avoidance
ontology: BP
definition:
The process in which dendrites recognize and avoid contact with sister dendrites from the same cell.


go_id: GO:0070594
term: juvenile hormone response element binding
ontology: MF
definition:
Binding to a juvenile hormone response element (JHRE), a conserved sequence found in the promoters of genes whose expression is regulated in response to juvenile hormone.


go_id: GO:0070595
term: (1->3)-alpha-glucan metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds.


go_id: GO:0070596
term: (1->3)-alpha-glucan biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds.


go_id: GO:0070597
term: cell wall (1->3)-alpha-glucan metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells.


go_id: GO:0070598
term: cell wall (1->3)-alpha-glucan biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-glucosidic bonds, found in the walls of cells.


go_id: GO:0070599
term: fungal-type cell wall (1->3)-alpha-glucan metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of ascospores.


go_id: GO:0070600
term: fungal-type cell wall (1->3)-alpha-glucan biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in fungal-type cell walls, including those of ascospores.


go_id: GO:0070601
term: centromeric sister chromatid cohesion
ontology: BP
definition:
The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the length of the centromeric region of the chromosome.


go_id: GO:0070602
term: regulation of centromeric sister chromatid cohesion
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of sister chromatid cohesion in the centromeric region of a chromosome.


go_id: GO:0070603
term: SWI/SNF superfamily-type complex
ontology: CC
definition:
A protein complex that contains an ortholog of the Saccharomyces ATPase Swi2/Snf2 as one of the catalytic subunit components (ATPase) and mediates assembly of nucleosomes, changes to the spacing or structure of nucleosomes, or some combination of those activities in a manner that requires ATP.


go_id: GO:0070605
term: regulation of (1->3)-alpha-glucan metabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds.


go_id: GO:0070606
term: regulation of (1->3)-alpha-glucan biosynthetic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds.


go_id: GO:0070607
term: regulation of cell wall (1->3)-alpha-glucan metabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells.


go_id: GO:0070608
term: regulation of cell wall (1->3)-alpha-glucan biosynthetic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells.


go_id: GO:0070609
term: regulation of fungal-type cell wall (1->3)-alpha-glucan metabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of ascospores.


go_id: GO:0070610
term: regulation of fungal-type cell wall (1->3)-alpha-glucan biosynthetic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in fungal-type cell walls, including those of ascospores.


go_id: GO:0070611
term: histone methyltransferase activity (H3-R2 specific)
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + (histone H3)-arginine (position 2) = S-adenosyl-L-homocysteine + (histone H3)-N-methyl-arginine (position 2). This reaction is the addition of a methyl group to arginine at position 2 of histone H3.


go_id: GO:0070612
term: histone methyltransferase activity (H2A-R3 specific)
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + (histone H2A)-arginine (position 3) = S-adenosyl-L-homocysteine + (histone H2A)-N-methyl-arginine (position 3). This reaction is the addition of a methyl group to arginine at position 3 of histone H2A.


go_id: GO:0070613
term: regulation of protein processing
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of protein processing, a protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein.


go_id: GO:0070614
term: tungstate ion transport
ontology: BP
definition:
The directed movement of tungstate (WO4 2-) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Tungstate is a bivalent oxoanion of tungsten.


go_id: GO:0070616
term: regulation of thiamine diphosphate biosynthetic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine diphosphate.


go_id: GO:0070617
term: negative regulation of thiamine diphosphate biosynthetic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine diphosphate.


go_id: GO:0070618
term: Grb2-Sos complex
ontology: CC
definition:
A protein complex that contains Grb2 and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway.


go_id: GO:0070619
term: Shc-Grb2-Sos complex
ontology: CC
definition:
A protein complex that contains Grb2, the adaptor protein Shc and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway.


go_id: GO:0070620
term: EGFR-Grb2-Sos complex
ontology: CC
definition:
A protein complex that contains the epidermal growth factor receptor (EGFR), Grb2 and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway.


go_id: GO:0070621
term: EGFR-Shc-Grb2-Sos complex
ontology: CC
definition:
A protein complex that contains the epidermal growth factor receptor (EGFR), Grb2, the adaptor protein SHC and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway.


go_id: GO:0070622
term: UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase complex
ontology: CC
definition:
A protein complex that possesses UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity; the bovine complex contains disulfide-linked homodimers of 166- and 51-kDa subunits and two identical, noncovalently associated 56-kDa subunits.


go_id: GO:0070623
term: regulation of thiamine biosynthetic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine.


go_id: GO:0070624
term: negative regulation of thiamine biosynthetic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine.


go_id: GO:0070625
term: zymogen granule exocytosis
ontology: BP
definition:
The release of intracellular molecules contained within the zymogen granule by fusion of the granule with the plasma membrane of the oocyte, requiring calcium ions.


go_id: GO:0070626
ontology: MF
term:
(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity

definition:
Catalysis of the reaction: (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate = fumarate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide.


go_id: GO:0070629
term: (1->4)-alpha-glucan metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving (1->4)-alpha-glucans, compounds composed of glucose residues linked by (1->4)-alpha-D-glucosidic bonds.


go_id: GO:0070630
term: (1->4)-alpha-glucan biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of (1->4)-alpha-glucans, compounds composed of glucose residues linked by (1->4)-alpha-D-glucosidic bonds.


go_id: GO:0070631
term: spindle pole body localization
ontology: BP
definition:
Any process in which a spindle pole body is transported to, or maintained in, a specific location. A spindle pole body is a type of microtubule organizing center found in fungal cells.


go_id: GO:0070637
term: pyridine nucleoside metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving any pyridine nucleoside, a nucleoside in which a pyridine base covalently bonded to a sugar, usually ribose.


go_id: GO:0070638
term: pyridine nucleoside catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of any pyridine nucleoside, a nucleoside in which a pyridine base covalently bonded to a sugar, usually ribose.


go_id: GO:0070639
term: vitamin D2 metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving vitamin D2, (3S,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol.


go_id: GO:0070640
term: vitamin D3 metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving vitamin D3, (3S,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol.


go_id: GO:0070641
term: vitamin D4 metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving vitamin D4, (3S,5Z,7E)-9,10-secoergosta-5,7,10(19)-trien-3-ol.


go_id: GO:0070642
term: vitamin D5 metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving vitamin D5, (1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,4S)-4-ethyl-1,5-dimethylhexyl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylene-1-cyclohexanol.


go_id: GO:0070644
term: vitamin D response element binding
ontology: MF
definition:
Binding to a vitamin D response element (VDRE), a short sequence with dyad symmetry found in the promoters of some of the cellular immediate-early genes, regulated by serum.


go_id: GO:0070645
term: Ubisch body
ontology: CC
definition:
A small, granular structure that is found in the extracellular matrix of cell of the secretory tapetal layer that surrounds developing pollen grains. Ubisch bodies have a sporopollenin coat, are attached to the peritapetal wall, and may play a role in pollen development.


go_id: GO:0070646
term: protein modification by small protein removal
ontology: BP
definition:
A protein modification process in which one or more covalently attached groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are removed from a target protein.


go_id: GO:0070647
term: protein modification by small protein conjugation or removal
ontology: BP
definition:
A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to or removed from a target protein.


go_id: GO:0070648
term: formin-nucleated actin cable
ontology: CC
definition:
An actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins. In fungal cells, myosin motors transport cargo along actin cables toward sites of polarized cell growth; actin cables may play a similar role in pollen tube growth.


go_id: GO:0070649
term: formin-nucleated actin cable assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins.


go_id: GO:0070650
term: actin filament bundle distribution
ontology: BP
definition:
Any cellular process that establishes the spatial arrangement of actin filament bundles within the cell.


go_id: GO:0070651
term: nonfunctional rRNA decay
ontology: BP
definition:
An rRNA catabolic process that results in the targeted detection and degradation of aberrant rRNAs contained within translationally defective ribosomes, thereby acting as a quality-control system.


go_id: GO:0070652
term: HAUS complex
ontology: CC
definition:
A protein complex that localizes to interphase centrosomes and to mitotic spindle tubules and regulates mitotic spindle assembly and centrosome integrity; in human, the complex consists of eight subunits, some of which are homologous to subunits of the Drosophila Augmin complex.


go_id: GO:0070664
term: negative regulation of leukocyte proliferation
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte proliferation.


go_id: GO:0070669
term: response to interleukin-2
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-2 stimulus.


go_id: GO:0070670
term: response to interleukin-4
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-4 stimulus.


go_id: GO:0070671
term: response to interleukin-12
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-12 stimulus.


go_id: GO:0070672
term: response to interleukin-15
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-15 stimulus.


go_id: GO:0070673
term: response to interleukin-18
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-18 stimulus.


go_id: GO:0070676
term: intralumenal vesicle formation
ontology: BP
definition:
The invagination of the endosome membrane and resulting formation of a vesicle within the lumen of the endosome.


go_id: GO:0070677
term: rRNA (cytosine-2'-O-)-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methylcytosine.


go_id: GO:0070678
term: preprotein binding
ontology: MF
definition:
Binding to a preprotein, the unprocessed form of a protein destined to undergo co- or post-translational processing.


go_id: GO:0070680
term: asparaginyl-tRNAAsn biosynthesis via transamidation
ontology: BP
definition:
A tRNA aminoacylation process in which asparaginyl-tRNAAsn is formed by a tRNA-dependent two-step pathway. In the first step a non-discriminating aspartyl-tRNA synthetase generates the misacylated L-aspartyl-tRNAAsn species, and in the second step it is amidated to the correctly charged L-asparaginyl-tRNAAsn by the heterotrimeric aspartyl-tRNAAsn amidotransferase.


go_id: GO:0070681
term: glutaminyl-tRNAGln biosynthesis via transamidation
ontology: BP
definition:
A tRNA aminoacylation process in which glutaminyl-tRNAGln is formed by a tRNA-dependent two-step pathway. In the first step a non-discriminating glutamyl-tRNAGlx synthetase generates the misacylated L-glutamyl-tRNAGln species, and in the second step it is amidated to the correctly charged L-glutaminyl-tRNAGln by a glutamyl-tRNAGln amidotransferase.


go_id: GO:0070682
term: proteasome regulatory particle assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a mature, active proteasome regulatory particle complex.


go_id: GO:0070684
term: seminal clot liquefaction
ontology: BP
definition:
The reproductive process in which coagulated semen becomes liquid following ejaculation, allowing the progressive release of motile spermatozoa.


go_id: GO:0070685
term: macropinocytic cup
ontology: CC
definition:
A cell projection that forms at the site of macropinocytosis, a form of endocytosis that results in the uptake of relatively large amounts of extracellular fluid. The macropinocytic cup membrane selectively excludes certain proteins, such as H36 or PM4C4 in Dictyostelium, and the underlying cytoskeleton is enriched in F-actin and coronin.


go_id: GO:0070689
term: L-threonine catabolic process to propionate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of L-threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) to form the compound propionate.


go_id: GO:0070690
term: L-threonine catabolic process to acetyl-CoA
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of L-threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) into glycine and acetaldehyde, with acetaldehyde being subsequently converted to acetyl-CoA.


go_id: GO:0070691
term: P-TEFb complex
ontology: CC
definition:
A dimeric positive transcription elongation factor complex b that comprises a cyclin-dependent kinase containing the catalytic subunit, Cdk9, and a regulatory subunit, cyclin T.


go_id: GO:0070692
term: CTDK-1 complex
ontology: CC
definition:
A positive transcription elongation factor complex that comprises the CDK kinase CTK1 (in budding yeast), Lsk1 (in fission yeast) (corresponding to the Panther PTHR24056:SF39 family), a cyclin and an additional gamma subunit (corresponding to the InterPRO entry IPR024638).


go_id: GO:0070693
term: P-TEFb-cap methyltransferase complex
ontology: CC
definition:
A protein complex that is formed by the association of positive transcription elongation factor complex b (P-TEFb) with the mRNA capping methyltransferase.


go_id: GO:0070694
term: deoxyribonucleoside 5'-monophosphate N-glycosidase activity
ontology: MF
definition:
Catalysis of the reaction: a deoxyribonucleoside 5'-monophosphate + H2O = deoxyribose 5-monophosphate + a purine or pyrimidine base.


go_id: GO:0070695
term: FHF complex
ontology: CC
definition:
A protein complex that is composed of AKTIP/FTS, FAM160A2/p107FHIP, and one or more members of the Hook family of proteins, HOOK1, HOOK2, and HOOK3. The complex is thought to promote vesicle trafficking and/or fusion, and associates with the homotypic vesicular sorting complex (the HOPS complex).


go_id: GO:0070696
term: transmembrane receptor protein serine/threonine kinase binding
ontology: MF
definition:
Binding to a receptor that spans a cell membrane and possesses protein serine/threonine kinase activity.


go_id: GO:0070701
term: mucus layer
ontology: CC
definition:
An extracellular region part that consists of a protective layer of mucus secreted by epithelial cells lining tubular organs of the body such as the colon or secreted into fluids such as saliva. Mucus is a viscous slimy secretion consisting of mucins (i.e. highly glycosylated mucin proteins) and various inorganic salts dissolved in water, with suspended epithelial cells and leukocytes.


go_id: GO:0070702
term: inner mucus layer
ontology: CC
definition:
The inner of two mucus layers secreted by epithelial cells in the colon; the inner mucus layer is firmly attached to the epithelium, is densely packed with a compact stratified appearance and is devoid of bacteria.


go_id: GO:0070703
term: outer mucus layer
ontology: CC
definition:
The outer of two mucus layers secreted by epithelial cells in the colon; the outer mucus layer is loosely packed and can be colonized by bacteria.


go_id: GO:0070715
term: sodium-dependent organic cation transport
ontology: BP
definition:
The directed, sodium-dependent, movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0070716
term: mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication
ontology: BP
definition:
A mismatch repair process that corrects errors introduced that ensures the accuracy of DNA replication.


go_id: GO:0070718
term: alphaPDGFR-SHP-2 complex
ontology: CC
definition:
A protein complex that contains the platelet-derived growth factor alpha receptor (alphaPDGFR; PDGFRA) and the adaptor protein SHP-2, and is involved signaling via the PDGFR signaling pathway.


go_id: GO:0070719
term: alphaPDGFR-PLC-gamma-1-PI3K-SHP-2 complex
ontology: CC
definition:
A protein complex that contains the platelet-derived growth factor alpha receptor (alphaPDGFR; PDGFRA), phospholipase C-gamma-1 (PLC-gamma-1), phosphatidylinositol 3-kinase (PI3K) and the adaptor protein SHP-2, and is involved signaling via the PDGFR signaling pathway.


go_id: GO:0070720
term: Grb2-SHP-2 complex
ontology: CC
definition:
A protein complex that contains the receptor adaptor proteins Grb2 and SHP-2, and is involved signaling via the PDGFR signaling pathway.


go_id: GO:0070722
term: Tle3-Aes complex
ontology: CC
definition:
A transcriptional repressor complex that consists of a heterodimer of the proteins Tle3 (also known as Grg3b) and Aes (Grg5), which are homologs of the Drosophila groucho gene product.


go_id: GO:0070723
term: response to cholesterol
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholesterol stimulus.


go_id: GO:0070724
term: BMP receptor complex
ontology: CC
definition:
A protein complex that acts as a receptor for bone morphogenetic proteins (BMPs); a homo- or heterodimer of type I and/or type II BMP receptor subunits.


go_id: GO:0070725
term: Yb body
ontology: CC
definition:
A cytoplasmic part that appears as an electron-dense sphere of around 1.5 micron diameter containing Yb protein found in somatic cells of ovary and testis. There are one to two Yb bodies per cell.


go_id: GO:0070726
term: cell wall assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, and most prokaryotic cells.


go_id: GO:0070727
term: cellular macromolecule localization
ontology: BP
definition:
Any process in which a macromolecule is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.


go_id: GO:0070729
term: cyclic nucleotide transport
ontology: BP
definition:
The directed movement of a cyclic nucleotide, any nucleotide in which phosphate group is in diester linkage to two positions on the sugar residue, into, out of or within a cell.


go_id: GO:0070732
term: spindle envelope
ontology: CC
definition:
An organelle envelope that surrounds the chromosomes and the central part of the spindle apparatus during mitosis and meiosis; observed in many invertebrates. The spindle envelope consists of membrane layers, called parafusorial membranes, derived from endoplasmic reticulum membrane; in male meiosis it forms during prometaphase and persists until early in the ensuing interphase.


go_id: GO:0070733
term: protein adenylyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: ATP + protein = diphosphate + adenylyl-protein; mediates the addition of an adenylyl (adenosine 5'-monophosphate; AMP group) to specific residues of target proteins.


go_id: GO:0070734
term: histone H3-K27 methylation
ontology: BP
definition:
The modification of histone H3 by addition of one or more methyl groups to lysine at position 27 of the histone.


go_id: GO:0070735
term: protein-glycine ligase activity
ontology: MF
definition:
Catalysis of the posttranslational transfer of one or more glycine residues to a specific glutamate residue on a target protein.


go_id: GO:0070736
term: protein-glycine ligase activity, initiating
ontology: MF
definition:
Catalysis of the posttranslational transfer of a glycine residue to the gamma-carboxyl group(s) of one or more specific glutamate residues on a target protein.


go_id: GO:0070737
term: protein-glycine ligase activity, elongating
ontology: MF
definition:
Catalysis of the posttranslational transfer of one or more glycine residues to a glycine residue covalently attached to the gamma-carboxyl group of a glutamate residue on a target protein, resulting in the elongation of a polyglycine side chain.


go_id: GO:0070738
term: tubulin-glycine ligase activity
ontology: MF
definition:
Catalysis of the posttranslational transfer of one or more glycine residues to a specific glutamate residue on a target tubulin molecule; acts on alpha or beta tubulin.


go_id: GO:0070739
term: protein-glutamic acid ligase activity
ontology: MF
definition:
Catalysis of the posttranslational transfer of one or more glutamate residues to a specific residue on a target protein.


go_id: GO:0070740
term: tubulin-glutamic acid ligase activity
ontology: MF
definition:
Catalysis of the posttranslational transfer of one or more glutamate residues to the gamma-carboxyl group(s) of one or more specific glutamate residues on a tubulin molecule.


go_id: GO:0070741
term: response to interleukin-6
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-6 stimulus.


go_id: GO:0070742
term: C2H2 zinc finger domain binding
ontology: MF
definition:
Binding to a C2H2-type zinc finger domain of a protein. The C2H2 zinc finger is the classical zinc finger domain, in which two conserved cysteines and histidines co-ordinate a zinc ion.


go_id: GO:0070743
term: interleukin-23 complex
ontology: CC
definition:
A protein complex that is composed of an interleukin-23 alpha (p19, product of the IL23A gene) and an interleukin-12 beta (p40, product of the IL12B gene) subunit and is secreted into the extracellular space.


go_id: GO:0070744
term: interleukin-27 complex
ontology: CC
definition:
A protein complex that is composed of an interleukin-27p28 subunit (product of the IL27 gene) and an EBI3 subunit and is secreted into the extracellular space.


go_id: GO:0070745
term: interleukin-35 complex
ontology: CC
definition:
A protein complex that is composed of an interleukin-12 alpha subunit (p35, product of the IL12A gene) and an EBI3 subunit and is secreted into the extracellular space.


go_id: GO:0070747
term: interleukin-35 receptor activity
ontology: MF
definition:
Combining with interleukin-35 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


go_id: GO:0070753
term: interleukin-35 production
ontology: BP
definition:
The appearance of interleukin-35 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0070755
term: negative regulation of interleukin-35 production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-35 production.


go_id: GO:0070756
term: positive regulation of interleukin-35 production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of interleukin-35 production.


go_id: GO:0070757
term: interleukin-35-mediated signaling pathway
ontology: BP
definition:
The series of molecular signals initiated by interleukin-35 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


go_id: GO:0070758
term: regulation of interleukin-35-mediated signaling pathway
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of an interleukin-35-mediated signaling pathway.


go_id: GO:0070759
term: negative regulation of interleukin-35-mediated signaling pathway
ontology: BP
definition:
Any process that decreases the rate, frequency or extent of an interleukin-35-mediated signaling pathway.


go_id: GO:0070760
term: positive regulation of interleukin-35-mediated signaling pathway
ontology: BP
definition:
Any process that increases the rate, frequency or extent of an interleukin-35-mediated signaling pathway.


go_id: GO:0070761
term: pre-snoRNP complex
ontology: CC
definition:
A ribonucleoprotein complex that contains a precursor small nucleolar RNA (pre-snoRNA) and associated proteins, and forms during small nucleolar ribonucleoprotein complex (snoRNP) assembly. Pre-snoRNP complexes may contain proteins not found in the corresponding mature snoRNP complexes.


go_id: GO:0070762
term: nuclear pore transmembrane ring
ontology: CC
definition:
A subcomplex of the nuclear pore complex (NPC) that spans the nuclear membrane and anchors the NPC to the nuclear envelope. In S. cerevisiae, the transmembrane ring is composed of Pom152p, Pom34p, and Ndc1p. In vertebrates, it is composed of Gp210, Ndc1, and Pom121. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. A single 'spoke', can be isolated and is sometime referred to as the Ndc1 complex.


go_id: GO:0070764
term: gamma-secretase-Delta1 complex
ontology: CC
definition:
A protein complex that is formed by the association of the Notch ligand Delta1 with the gamma-secretase complex.


go_id: GO:0070765
term: gamma-secretase complex
ontology: CC
definition:
A protein complex that has aspartic-type endopeptidase activity and contains a presenilin catalytic subunit (either PSEN1 or PSEN2), an APH1 subunit (multiple genes and splice variants exist), nicastrin (NCT), and presenilin enhancer (aka PEN-2 or Psenen), as the core complex. Variants of the complex with different subunit compositions differ in localization and specific substrates. Additionally, variants of the complex exist that contain a additional regulatory subunit as well as the four core subunits; known regulatory subunits include gamma-secretase-activating protein (aka gSAP), TMP1 (aka TMED10), and CD147 antigen (aka basigin). Gamma-secretase cleaves type I transmembrane protein substrates, including the cell surface receptor Notch and the amyloid-beta precursor protein.


go_id: GO:0070766
term: endobrevin-synaptobrevin 2-alpha-SNAP-NSF-syntaxin-4 complex
ontology: CC
definition:
A SNARE complex that contains endobrevin (VAMP8), synaptobrevin 2 (VAMP2), alpha-SNAP, NSF, and syntaxin 4 (or orthologs thereof).


go_id: GO:0070767
term: BRCA1-Rad51 complex
ontology: CC
definition:
A protein complex that contains BRCA1 and Rad 51, and is involved in the control of recombination and of genome integrity.


go_id: GO:0070768
term: synaptotagmin-synaptobrevin 2-SNAP-25-syntaxin-1a-syntaxin-1b-Unc13 complex
ontology: CC
definition:
A SNARE complex that contains synaptotagmin, synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, syntaxin1b, and Unc13b (or orthologs thereof).


go_id: GO:0070769
term: alphaIIb-beta3 integrin-CIB complex
ontology: CC
definition:
A protein complex that consists of an alphaIIb-beta3 integrin complex bound to CIB, a protein that binds calcium as well as the alphaIIb-beta3 integrin.


go_id: GO:0070770
term: alphaIIb-beta3 integrin-CD47-FAK complex
ontology: CC
definition:
A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface antigen CD47 and the kinase FAK.


go_id: GO:0070771
term: alphaIIb-beta3 integrin-CD47-Src complex
ontology: CC
definition:
A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface antigen CD47 and the kinase c-Src.


go_id: GO:0070772
term: PAS complex
ontology: CC
definition:
A class III phosphatidylinositol 3-kinase complex that contains a phosphatidylinositol-3-phosphate 5-kinase subunit (Fab1p in yeast; PIKfyve in mammals), a kinase activator, and a phosphatase, and may also contain additional proteins; it is involved in regulating the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate. In mammals the complex is composed of PIKFYVE, FIG4 and VAC14. In yeast it is composed of Atg18p, Fig4p, Fab1p, Vac14p and Vac7p.


go_id: GO:0070773
term: protein-N-terminal glutamine amidohydrolase activity
ontology: MF
definition:
Catalysis of the reaction:  N-terminal L-glutaminyl-[protein] + H2O = N-terminal L-glutamyl-[protein] + NH3. This reaction is the deamidation of an N-terminal glutamine residue of a protein.


go_id: GO:0070776
term: MOZ/MORF histone acetyltransferase complex
ontology: CC
definition:
A histone acetyltransferase complex that has histone H3 acetyltransferase and coactivator activities. Subunits of the human complex include MYST3/MOZ, MYST4/MORF, ING5, EAF6 and one of BRPF1, BRD1/BRPF2 and BRPF3.


go_id: GO:0070777
term: D-aspartate transport
ontology: BP
definition:
The directed movement of D-aspartate, the D-enantiomer of the anion of (2R)-2-aminobutanedioic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0070779
term: D-aspartate import across plasma membrane
ontology: BP
definition:
The directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol.


go_id: GO:0070781
term: response to biotin
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotin stimulus.


go_id: GO:0070782
term: phosphatidylserine exposure on apoptotic cell surface
ontology: BP
definition:
A phospholipid scrambling process that results in the appearance of phosphatidylserine on the outer leaflet of the plasma membrane of an apoptotic cell, which acts as an 'eat-me' signal for engulfing cells. Phosphatidylserine is exposed on the apoptotic cell surface by a phospholipid scramblase activity.


go_id: GO:0070783
term: growth of unicellular organism as a thread of attached cells
ontology: BP
definition:
A filamentous growth process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium such as an agar plate, exhibited by unicellular fungi under certain growth conditions.


go_id: GO:0070784
term: regulation of growth of unicellular organism as a thread of attached cells
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium.


go_id: GO:0070785
term: negative regulation of growth of unicellular organism as a thread of attached cells
ontology: BP
definition:
Any process that decreases the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium.


go_id: GO:0070786
term: positive regulation of growth of unicellular organism as a thread of attached cells
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium.


go_id: GO:0070787
term: conidiophore development
ontology: BP
definition:
The process whose specific outcome is the progression of the conidiophore over time, from its formation to the mature structure. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores.


go_id: GO:0070788
term: conidiophore stalk development
ontology: BP
definition:
The process whose specific outcome is the progression of the conidiophore stalk over time, from its formation to the mature structure. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop.


go_id: GO:0070789
term: metula development
ontology: BP
definition:
The process whose specific outcome is the progression of metulae over time, from its formation to the mature structure. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip.


go_id: GO:0070790
term: phialide development
ontology: BP
definition:
The process whose specific outcome is the progression of phialides over time, from its formation to the mature structure. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip. Chains of conidia, or asexual spores, develop from the phialide tips.


go_id: GO:0070791
term: cleistothecium development
ontology: BP
definition:
The process whose specific outcome is the progression of the cleistothecium over time, from its formation to the mature structure. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.


go_id: GO:0070792
term: Hulle cell development
ontology: BP
definition:
The process whose specific outcome is the progression of Hulle cells over time, from their formation to the mature structures. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body.


go_id: GO:0070793
term: regulation of conidiophore development
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores.


go_id: GO:0070794
term: negative regulation of conidiophore development
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores.


go_id: GO:0070795
term: positive regulation of conidiophore development
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores.


go_id: GO:0070796
term: regulation of cleistothecium development
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.


go_id: GO:0070797
term: negative regulation of cleistothecium development
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.


go_id: GO:0070798
term: positive regulation of cleistothecium development
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.


go_id: GO:0070799
term: regulation of conidiophore stalk development
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of conidiophore stalk development, a process that leads to the formation of a conidiophore stalk. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop.


go_id: GO:0070800
term: negative regulation of conidiophore stalk development
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of conidiophore stalk development, a process that leads to the formation of a conidiophore stalk. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop.


go_id: GO:0070801
term: positive regulation of conidiophore stalk development
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of conidiophore stalk development, a process that leads to the formation of a conidiophore stalk. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop.


go_id: GO:0070802
term: regulation of metula development
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip.


go_id: GO:0070803
term: negative regulation of metula development
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip.


go_id: GO:0070804
term: positive regulation of metula development
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip.


go_id: GO:0070805
term: regulation of phialide development
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of phialide development, a process that leads to the formation of phialides. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip.


go_id: GO:0070806
term: negative regulation of phialide development
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of phialide development, a process that leads to the formation of phialides. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip.


go_id: GO:0070807
term: positive regulation of phialide development
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of phialide development, a process that leads to the formation of phialides. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip.


go_id: GO:0070808
term: regulation of Hulle cell development
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body.


go_id: GO:0070809
term: negative regulation of Hulle cell development
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body.


go_id: GO:0070810
term: positive regulation of Hulle cell development
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body.


go_id: GO:0070811
term: glycerol-2-phosphate transmembrane transport
ontology: BP
definition:
The process in which glycerol-2-phosphate is transported across a membrane. Glycerol-2-phosphate is a phosphoric monoester of glycerol.


go_id: GO:0070815
term: peptidyl-lysine 5-dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: protein L-lysine + 2-oxoglutarate + O2 = protein 5-hydroxy-L-lysine + succinate + CO2.


go_id: GO:0070816
term: phosphorylation of RNA polymerase II C-terminal domain
ontology: BP
definition:
The process of introducing a phosphate group on to an amino acid residue in the C-terminal domain of RNA polymerase II. Typically, this occurs during the transcription cycle and results in production of an RNA polymerase II enzyme where the carboxy-terminal domain (CTD) of the largest subunit is extensively phosphorylated, often referred to as hyperphosphorylated or the II(0) form. Specific types of phosphorylation within the CTD are usually associated with specific regions of genes, though there are exceptions. The phosphorylation state regulates the association of specific complexes such as the capping enzyme or 3'-RNA processing machinery to the elongating RNA polymerase complex.


go_id: GO:0070817
term: P-TEFb-cap methyltransferase complex localization
ontology: BP
definition:
Any process in which the P-TEFb-cap methyltransferase complex is transported to, or maintained in, a specific location.


go_id: GO:0070819
term: menaquinone-dependent protoporphyrinogen oxidase activity
ontology: MF
definition:
Catalysis of the reaction: protoporphyrinogen IX + menaquinone = protoporphyrin IX + reduced menaquinone.


go_id: GO:0070820
term: tertiary granule
ontology: CC
definition:
A secretory granule that contains cathepsin and gelatinase and is readily exocytosed upon cell activation; found primarily in mature neutrophil cells.


go_id: GO:0070822
term: Sin3-type complex
ontology: CC
definition:
Any of a number of evolutionarily conserved histone deacetylase complexes (HDACs) containing a core consisting of a paired amphipathic helix motif protein (e.g. Sin3p in S. cerevisiae, Pst1 in S. pombe or Sin3A in mammals) at least one class I histone deacetylase (e.g. Rpd3p in S. cerevisiae, Clr6 in S. pombe, or HDAC1 and HDAC2 in mammals), and at least one WD40 repeat protein (e.g. Ume1p in S. cerevisiae, Prw1 in S. pombe, or RbAp46 and RbAp48 in mammals). These complexes also contain a variable number of other proteins that direct histone binding, DNA binding, or add other functionality to the complex.


go_id: GO:0070823
term: HDA1 complex
ontology: CC
definition:
A tetrameric histone deacetylase complex that contains a Class II deacetylase catalytic subunit. In S. cerevisiae it is composed of two Hda1p subunits along with Hda2p and Hda3p.


go_id: GO:0070824
term: SHREC complex
ontology: CC
definition:
A histone deacetylase complex that contains a core of four proteins -- Clr1, Clr2, Clr3, and Mit1 in fission yeast -- and localizes to all heterochromatic regions in the genome as well as some euchromatic sites. The complex is involved in regulating nucleosome positioning to assemble higher-order chromatin structures.


go_id: GO:0070825
term: micropyle
ontology: CC
definition:
An external encapsulating structure part of the chorion. A single cone-shaped specialization that forms an opening in the egg chorion that allows sperm entry into the egg prior to fertilization.


go_id: GO:0070826
term: paraferritin complex
ontology: CC
definition:
A cytoplasmic protein complex that contains integrin, mobilferrin and a flavin monooxygenase, is capable of reducing Fe(III) to Fe(II) utilizing NADPH, and is involved in iron transport. Fe(II) is required in the cell as the substrate for ferrochelatase in the synthesis of heme.


go_id: GO:0070828
term: heterochromatin organization
ontology: BP
definition:
Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic heterochromatin, a compact and highly condensed form of chromatin.


go_id: GO:0070830
term: bicellular tight junction assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form a tight junction, an occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet.


go_id: GO:0070831
term: basement membrane assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form a basement membrane, a part of the extracellular region that consists of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue.


go_id: GO:0070832
ontology: BP
term:
phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-choline

definition:
The phosphatidylcholine biosynthetic process that begins with three consecutive N-methylation steps that are carried out on phospho-bases, phosphoethanolamine, phospho-N-methylethanolamine, and phospho-N-dimethylethanolamine; the process ends with the conversion of a phosphatidyl-N-dimethylethanolamine to a phosphatidylcholine.


go_id: GO:0070833
term: phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via CDP-N-methylethanolamine
ontology: BP
definition:
The phosphatidylcholine biosynthetic process that begins with an initial N-methylation with phospho-base phosphoethanolamine, followed by two downstream N-methylations on phosphatidyl-bases, phosphatidyl-N-methylethanolamine and phosphatidyl-N-dimethylethanolamine. The process ends with the conversion of a phosphatidyl-N-dimethylethanolamine to a phosphatidylcholine.


go_id: GO:0070834
ontology: BP
term:
phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-N-dimethylethanolamine

definition:
The phosphatidylcholine biosynthetic process that begins with two N-methylations with phospho-base phosphoethanolamine and phospho-N-methylethanolamine, followed by a downstream N-methylation on phosphatidyl-base phosphatidyl-N-dimethylethanolamine; the process ends with the conversion of a phosphatidyl-N-dimethylethanolamine to a phosphatidylcholine.


go_id: GO:0070836
term: caveola assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form a caveola. A caveola is a plasma membrane raft that forms a small pit, depression, or invagination that communicates with the outside of a cell and extends inward, indenting the cytoplasm and the cell membrane.


go_id: GO:0070837
term: dehydroascorbic acid transport
ontology: BP
definition:
The directed movement of dehydroascorbate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dehydroascorbate, 5-(1,2-dihydroxyethyl)furan-2,3,4(5H)-trione, is an oxidized form of vitamin C.


go_id: GO:0070840
term: dynein complex binding
ontology: MF
definition:
Binding to a dynein complex, a protein complex that contains two or three dynein heavy chains and several light chains, and has microtubule motor activity.


go_id: GO:0070842
term: aggresome assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form an aggresome; requires the microtubule cytoskeleton and dynein.


go_id: GO:0070843
term: misfolded protein transport
ontology: BP
definition:
The directed movement of misfolded proteins in a cell, including the movement of proteins between specific compartments or structures within a cell.


go_id: GO:0070844
term: polyubiquitinated protein transport
ontology: BP
definition:
The directed movement of polyubiquitinated proteins in a cell, including the movement of proteins between specific compartments or structures within a cell.


go_id: GO:0070845
term: polyubiquitinated misfolded protein transport
ontology: BP
definition:
The directed movement of misfolded polyubiquitinated proteins in a cell, including the movement of proteins between specific compartments or structures within a cell.


go_id: GO:0070847
term: core mediator complex
ontology: CC
definition:
A protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The core mediator complex has a stimulatory effect on basal transcription, and contains most of the same subdomains as the larger form of mediator complex -- a head domain comprising proteins known in Saccharomyces as Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; and a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p -- but lacks the regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan core mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins.


go_id: GO:0070848
term: response to growth factor
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.


go_id: GO:0070849
term: response to epidermal growth factor
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus.


go_id: GO:0070850
term: TACC/TOG complex
ontology: CC
definition:
A protein complex that contains the transforming acidic coiled coil (TACC) protein and the TOG protein (Mia1p/Alp7p and Alp14, respectively, in fission yeast), and is involved in microtubule array remodeling as cells progress through the cell cycle. The TACC/TOG complex is conserved in eukaryotes, associates with microtubules, and shuttles between the nucleus and the cytoplasm during interphase.


go_id: GO:0070852
term: cell body fiber
ontology: CC
definition:
A neuron projection that is found in unipolar neurons and corresponds to the region between the cell body and the point at which the single projection branches.


go_id: GO:0070853
term: myosin VI binding
ontology: MF
definition:
Binding to a class VI myosin. The myosin VI heavy chain has a single IQ motif in the neck and a tail region with a coiled coil domain followed by a unique globular domain, a unique insertion that enables myosin VI to move towards the pointed or minus end of actin filaments.


go_id: GO:0070857
term: regulation of bile acid biosynthetic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids.


go_id: GO:0070858
term: negative regulation of bile acid biosynthetic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids.


go_id: GO:0070859
term: positive regulation of bile acid biosynthetic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids.


go_id: GO:0070860
term: RNA polymerase I core factor complex
ontology: CC
definition:
A RNA polymerase I-specific transcription factor complex that is required for the transcription of rDNA by RNA polymerase I. In yeast the complex consists of Rrn6p, Rrn7p, and Rrn11p.


go_id: GO:0070861
term: regulation of protein exit from endoplasmic reticulum
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the directed movement of proteins from the endoplasmic reticulum.


go_id: GO:0070862
term: negative regulation of protein exit from endoplasmic reticulum
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of proteins from the endoplasmic reticulum.


go_id: GO:0070863
term: positive regulation of protein exit from endoplasmic reticulum
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the endoplasmic reticulum.


go_id: GO:0070864
term: sperm individualization complex
ontology: CC
definition:
A macromolecular complex that includes cytoskeletal components and part of the cell membrane. Forms at the nuclear end of a male germline syncytium, or cyst, and translocates the over the length of the syncytium in the course of sperm individualization. Each complex contains an array of 64 investment cones, one per nucleus, that move synchronously along the spermatogenic cyst.


go_id: GO:0070865
term: investment cone
ontology: CC
definition:
A cytoskeletal part that consists of a microfilament-rich cone that forms round each nucleus in a spermatogenic cyst and translocates the length of the cyst during sperm individualization.


go_id: GO:0070873
term: regulation of glycogen metabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glycogen.


go_id: GO:0070874
term: negative regulation of glycogen metabolic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glycogen.


go_id: GO:0070875
term: positive regulation of glycogen metabolic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glycogen.


go_id: GO:0070876
term: SOSS complex
ontology: CC
definition:
A protein complex that functions downstream of the MRN complex to promote DNA repair and the G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and is composed of SOSS-B (SOSS-B1/OBFC2B or SOSS-B2/OBFC2A), SOSS-A/INTS3 and SOSS-C/C9orf80.


go_id: GO:0070877
term: microprocessor complex
ontology: CC
definition:
A protein complex that binds to heme and to pri-miRNAs, and is required for the formation of a pre-microRNA (pre-miRNA), the initial step of microRNA (miRNA) biogenesis. The complex is composed of the double-stranded-RNA-specific RNase Drosha (also called RNASEN) and the RNA-binding protein DGCR8 (heme-free or heme-bound forms). Within the complex, DGCR8 function as a molecular anchor necessary for the recognition of pri-miRNA at dsRNA-ssRNA junction and directs RNASEN/Drosha to cleave the 3' and 5' strands of a stem-loop to release hairpin-shaped pre-miRNAs.


go_id: GO:0070878
term: primary miRNA binding
ontology: MF
definition:
Binding to a primary microRNA (pri-miRNA) transcript, an RNA molecule that is processed into a short hairpin-shaped structure called a pre-miRNA and finally into a functional miRNA. Both double-stranded and single-stranded regions of a pri-miRNA are required for binding.


go_id: GO:0070879
term: fungal-type cell wall beta-glucan metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of fungal cells.


go_id: GO:0070880
term: fungal-type cell wall beta-glucan biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of fungal cells.


go_id: GO:0070883
term: pre-miRNA binding
ontology: MF
definition:
Binding to a precursor microRNA (pre-miRNA) transcript, a stem-loop-containing precursor of microRNA.


go_id: GO:0070885
term: negative regulation of calcineurin-NFAT signaling cascade
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the calcineurin-NFAT signaling cascade.


go_id: GO:0070886
term: positive regulation of calcineurin-NFAT signaling cascade
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of signaling via the calcineurin-NFAT signaling cascade.


go_id: GO:0070887
term: cellular response to chemical stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.


go_id: GO:0070888
term: E-box binding
ontology: MF
definition:
Binding to an E-box, a DNA motif with the consensus sequence CANNTG that is found in the promoters of a wide array of genes expressed in neurons, muscle and other tissues.


go_id: GO:0070889
term: platelet alpha granule organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a platelet alpha granule. A platelet alpha granule is a secretory organelle found in blood platelets.


go_id: GO:0070893
term: transposon integration
ontology: BP
definition:
Any process in which a transposable element is incorporated into another DNA molecule such as a chromosome.


go_id: GO:0070894
term: regulation of transposon integration
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of regulation of transposon integration, a process in which a transposable element is incorporated into another DNA molecule.


go_id: GO:0070895
term: negative regulation of transposon integration
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of transposon integration, a process in which a transposable element is incorporated into another DNA molecule.


go_id: GO:0070896
term: positive regulation of transposon integration
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of transposon integration, a process in which a transposable element is incorporated into another DNA molecule.


go_id: GO:0070897
term: transcription preinitiation complex assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of proteins on promoter DNA to form the transcriptional preinitiation complex (PIC), required for transcription.


go_id: GO:0070898
term: RNA polymerase III preinitiation complex assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of proteins on promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription from an RNA polymerase III promoter.


go_id: GO:0070899
term: mitochondrial tRNA wobble uridine modification
ontology: BP
definition:
The process in which a uridine in position 34 of a mitochondrial tRNA is post-transcriptionally modified.


go_id: GO:0070900
term: mitochondrial tRNA modification
ontology: BP
definition:
The covalent alteration of one or more nucleotides within a mitochondrial tRNA molecule to produce a mitochondrial tRNA molecule with a sequence that differs from that coded genetically.


go_id: GO:0070901
term: mitochondrial tRNA methylation
ontology: BP
definition:
The posttranscriptional addition of methyl groups to specific residues in a mitochondrial tRNA molecule.


go_id: GO:0070909
term: glutamate:gamma-aminobutyric acid antiporter activity
ontology: MF
definition:
Catalysis of the reaction: glutamate(out) + gamma-aminobutyric acid(in) = glutamate(in) + gamma-aminobutyric acid(out).


go_id: GO:0070910
term: cell wall macromolecule catabolic process involved in cell wall disassembly
ontology: BP
definition:
The chemical reactions and pathways that result in the breakdown of macromolecules that form part of a cell wall, and contributes to the breakdown of the cell wall.


go_id: GO:0070911
term: global genome nucleotide-excision repair
ontology: BP
definition:
The nucleotide-excision repair process in which DNA lesions are removed from nontranscribed strands and from transcriptionally silent regions over the entire genome.


go_id: GO:0070912
term: Ddb1-Ckn1 complex
ontology: CC
definition:
A heterodimeric nucleotide-excision repair complex that is involved in transcription-coupled repair. The subunits are known as Ddb1 and Ckn1 in S. pombe; Ddb1 contains a motif called the DDB-box that interacts with adaptor proteins for DDB1/cullin 4 ubiquitin ligases.


go_id: GO:0070913
term: Ddb1-Wdr21 complex
ontology: CC
definition:
A heterodimeric nucleotide-excision repair complex that is involved in transcription-coupled repair. The subunits are known as Ddb1 and Wdr21 in S. pombe; Ddb1 contains a motif called the DDB-box that interacts with adaptor proteins for DDB1/cullin 4 ubiquitin ligases.


go_id: GO:0070914
term: UV-damage excision repair
ontology: BP
definition:
A DNA repair process that is initiated by an endonuclease that introduces a single-strand incision immediately 5' of a UV-induced damage site. UV-damage excision repair acts on both cyclobutane pyrimidine dimers (CPDs) and pyrimidine-pyrimidone 6-4 photoproducts (6-4PPs).


go_id: GO:0070915
term: lysophosphatidic acid receptor activity
ontology: MF
definition:
Combining with the phospholipid derivative lysophosphatidic acid, and transmitting the signal across the membrane by activating an associated G-protein.


go_id: GO:0070916
term: inositol phosphoceramide synthase complex
ontology: CC
definition:
A protein complex that possesses inositol phosphoceramide synthase activity and contains a catalytic subunit and a regulatory subunit (Aur1p and Kei1p, respectively, in Saccharomyces).


go_id: GO:0070920
term: regulation of production of small RNA involved in gene silencing by RNA
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the production of small RNA involved in gene silencing by RNA.


go_id: GO:0070921
term: regulation of siRNA production
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the production of siRNA, the cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides, in the context of gene silencing by small RNA.


go_id: GO:0070922
term: RISC complex assembly
ontology: BP
definition:
The process in which a single-stranded small RNA is incorporated within the RNA-initiated silencing complex (RISC). The assembly includes the maturation of the small RNA, the stabilization of the complex by accessory proteins of the RISC complex, duplex separation and the release of the second strand, forming a base-pairing completent complex that mediates gene silencing by small RNA.


go_id: GO:0070925
term: organelle assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.


go_id: GO:0070928
term: regulation of mRNA stability, ncRNA-mediated
ontology: BP
definition:
Any process, mediated by small non-coding RNAs, that modulates the propensity of mRNA molecules to degradation. Includes processes that both stabilize and destabilize mRNAs.


go_id: GO:0070929
term: trans-translation
ontology: BP
definition:
A translational elongation process in which transfer of a translating ribosome from one mRNA to another RNA template takes place. Trans-translation occurs during tmRNA release of stalled ribosomes.


go_id: GO:0070930
term: trans-translation-dependent protein tagging
ontology: BP
definition:
A protein modification process in which a polypeptide is added to a nascent polypeptide cotranslationally by trans-translation.


go_id: GO:0070934
term: CRD-mediated mRNA stabilization
ontology: BP
definition:
An mRNA stabilization process in which one or more RNA-binding proteins associate with a sequence in the open reading frame called the coding region instability determinant (CRD).


go_id: GO:0070935
term: 3'-UTR-mediated mRNA stabilization
ontology: BP
definition:
An mRNA stabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA.


go_id: GO:0070936
term: protein K48-linked ubiquitination
ontology: BP
definition:
A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation.


go_id: GO:0070937
term: CRD-mediated mRNA stability complex
ontology: CC
definition:
A protein complex that binds to, and promotes stabilization of, mRNA molecules containing the coding region instability determinant (CRD). In human, it may consist of IGF2BP1, HNRNPU, SYNCRIP/HNRNPQ, YBX1, and DHX9.


go_id: GO:0070938
term: contractile ring
ontology: CC
definition:
A cytoskeletal structure composed of filamentous protein that forms beneath the membrane of many cells or organelles, in the plane of cell or organelle division. Ring contraction is associated with centripetal growth of the membrane that divides the cytoplasm of the two daughter cells or organelles.


go_id: GO:0070939
term: Dsl1/NZR complex
ontology: CC
definition:
A multisubunit tethering complex, i.e. a protein complex involved in mediating the initial interaction between vesicles and the membranes with which they fuse, that is involved in trafficking from the Golgi apparatus to the ER. In Saccharomyces cerevisiae the Dsl1p complex contains Dsl1p, Tip20p, and Sec39p.


go_id: GO:0070940
term: dephosphorylation of RNA polymerase II C-terminal domain
ontology: BP
definition:
The process of removing a phosphate group from an amino acid residue in the C-terminal domain of RNA polymerase II. Some dephosphorylation occurs during transcription while some may occur after the enzyme is released from the template in order to prepare it for the beginning of the transcription cycle again. RNA polymerase II with little or no phosphorylation is referred to as the hypophosphorylated or II(A) form.


go_id: GO:0070941
term: eisosome assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form an eisosome, a cell part that is composed of the eisosome membrane and eisosome filaments. The eisosome membrane, also called the MCC domain, is a furrow-like plasma membrane sub-domain with associated integral transmembrane proteins. The eisosome filaments form a scaffolding lattice on the cytoplasmic face of the membrane.


go_id: GO:0070943
term: neutrophil-mediated killing of symbiont cell
ontology: BP
definition:
The directed killing of a symbiont target cell by a neutrophil. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.


go_id: GO:0070948
term: regulation of neutrophil mediated cytotoxicity
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a target cell, the directed killing of a target cell by a neutrophil.


go_id: GO:0070949
term: regulation of neutrophil mediated killing of symbiont cell
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a symbiont cell, the directed killing of a symbiont target cell by a neutrophil.


go_id: GO:0070950
term: regulation of neutrophil mediated killing of bacterium
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a bacterium, the directed killing of a bacterium by a neutrophil.


go_id: GO:0070951
term: regulation of neutrophil mediated killing of gram-negative bacterium
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a gram-negative bacterium, the directed killing of a gram-negative bacterium by a neutrophil.


go_id: GO:0070952
term: regulation of neutrophil mediated killing of gram-positive bacterium
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a gram-positive bacterium, the directed killing of a gram-positive bacterium by a neutrophil.


go_id: GO:0070953
term: regulation of neutrophil mediated killing of fungus
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a fungal cell, the directed killing of a fungal cell by a neutrophil.


go_id: GO:0070954
term: negative regulation of neutrophil mediated cytotoxicity
ontology: BP
definition:
Any process that decreases the frequency, rate or extent of the directed killing of a target cell by a neutrophil.


go_id: GO:0070955
term: negative regulation of neutrophil mediated killing of symbiont cell
ontology: BP
definition:
Any process that decreases the frequency, rate or extent of the directed killing of a symbiont target cell by a neutrophil.


go_id: GO:0070956
term: negative regulation of neutrophil mediated killing of bacterium
ontology: BP
definition:
Any process that decreases the frequency, rate or extent of the directed killing of a bacterium by a neutrophil.


go_id: GO:0070957
term: negative regulation of neutrophil mediated killing of gram-negative bacterium
ontology: BP
definition:
Any process that decreases the frequency, rate or extent of the directed killing of a gram-negative bacterium by a neutrophil.


go_id: GO:0070958
term: negative regulation of neutrophil mediated killing of gram-positive bacterium
ontology: BP
definition:
Any process that decreases the frequency, rate or extent of the directed killing of a gram-positive bacterium by a neutrophil.


go_id: GO:0070959
term: negative regulation of neutrophil mediated killing of fungus
ontology: BP
definition:
Any process that decreases the frequency, rate or extent of the directed killing of a fungal cell by a neutrophil.


go_id: GO:0070960
term: positive regulation of neutrophil mediated cytotoxicity
ontology: BP
definition:
Any process that increases the frequency, rate or extent of the directed killing of a target cell by a neutrophil.


go_id: GO:0070961
term: positive regulation of neutrophil mediated killing of symbiont cell
ontology: BP
definition:
Any process that increases the frequency, rate or extent of the directed killing of a symbiont target cell by a neutrophil.


go_id: GO:0070962
term: positive regulation of neutrophil mediated killing of bacterium
ontology: BP
definition:
Any process that increases the frequency, rate or extent of the directed killing of a bacterium by a neutrophil.


go_id: GO:0070963
term: positive regulation of neutrophil mediated killing of gram-negative bacterium
ontology: BP
definition:
Any process that increases the frequency, rate or extent of the directed killing of a gram-negative bacterium by a neutrophil.


go_id: GO:0070964
term: positive regulation of neutrophil mediated killing of gram-positive bacterium
ontology: BP
definition:
Any process that increases the frequency, rate or extent of the directed killing of a gram-positive bacterium by a neutrophil.


go_id: GO:0070965
term: positive regulation of neutrophil mediated killing of fungus
ontology: BP
definition:
Any process that increases the frequency, rate or extent of the directed killing of a fungal cell by a neutrophil.


go_id: GO:0070966
term: nuclear-transcribed mRNA catabolic process, no-go decay
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA with stalls in translation elongation.


go_id: GO:0070967
term: coenzyme F420 binding
ontology: MF
definition:
Binding to F420, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.


go_id: GO:0070968
term: pyrroloquinoline quinone binding
ontology: MF
definition:
Binding to pyrroloquinoline quinone, PQQ, the coenzyme or the prosthetic group of certain alcohol dehydrogenases and glucose dehydrogenases.


go_id: GO:0070972
term: protein localization to endoplasmic reticulum
ontology: BP
definition:
A process in which a protein is transported to, or maintained in, a location within the endoplasmic reticulum.


go_id: GO:0070973
term: protein localization to endoplasmic reticulum exit site
ontology: BP
definition:
A process in which a protein is transported to, or maintained in, a location at an endoplasmic reticulum exit site.


go_id: GO:0070974
term: POU domain binding
ontology: MF
definition:
Binding to a POU domain of a protein. The POU domain is a bipartite DNA binding domain composed of two subunits separated by a non-conserved region of 15-55 amino acids; it is found in several eukaryotic transcription factors.


go_id: GO:0070975
term: FHA domain binding
ontology: MF
definition:
Binding to a FHA domain of a protein. The FHA domain is a phosphopeptide recognition domain found in many regulatory proteins, and consists of approximately 80-100 amino acid residues folded into an 11-stranded beta sandwich.


go_id: GO:0070976
term: TIR domain binding
ontology: MF
definition:
Binding to a Toll-Interleukin receptor (TIR) domain of a protein. The TIR domain is an intracellular 200 residue domain that is found in the Toll protein, the interleukin-1 receptor (IL-1R), and MyD88; it contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components.


go_id: GO:0070977
term: bone maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for bone to attain its fully functional state.


go_id: GO:0070978
term: voltage-gated calcium channel complex assembly
ontology: BP
definition:
Cellular protein complex assembly that results in the formation of a voltage-gated calcium channel complex.


go_id: GO:0070979
term: protein K11-linked ubiquitination
ontology: BP
definition:
A protein ubiquitination process in which ubiquitin monomers are attached to a protein, and then ubiquitin polymers are formed by linkages between lysine residues at position 11 of the ubiquitin monomers. K11-linked polyubiquitination targets the substrate protein for degradation. The anaphase-promoting complex promotes the degradation of mitotic regulators by assembling K11-linked polyubiquitin chains.


go_id: GO:0070980
term: biphenyl catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of biphenyl, a toxic aromatic hydrocarbon used as a heat transfer agent, as a fungistat in packaging citrus fruits and in plant disease control. Biphenyl can be chlorinated with 1-10 chlorine molecules to form polychlorinated biphenyls (PCBs).


go_id: GO:0070981
term: L-asparagine biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of asparagine, (2S)-2-amino-3-carbamoylpropanoic acid.


go_id: GO:0070983
term: dendrite guidance
ontology: BP
definition:
The process in which the migration of a dendrite is directed to a specific target site in response to a combination of attractive and repulsive cues.


go_id: GO:0070984
term: SET domain binding
ontology: MF
definition:
Binding to a SET domain of a protein. SET domains are named after three Drosophila proteins that contain this domain: Su(var), E(z) and trithorax. SET domains are associated with histone lysine methylation.


go_id: GO:0070985
term: transcription factor TFIIK complex
ontology: CC
definition:
A transcription factor complex that forms part of the holo TFIIH complex. In Saccharomyces/human, TFIIK contains Ccl1p/Cyclin H, Tfb3p/MAT1 and Kin28p/CDK7.


go_id: GO:0070986
term: left/right axis specification
ontology: BP
definition:
The establishment, maintenance and elaboration of the left/right axis. The left/right axis is defined by a line that runs orthogonal to both the anterior/posterior and dorsal/ventral axes. Each side is defined from the viewpoint of the organism rather of the observer (as per anatomical axes).


go_id: GO:0070987
term: error-free translesion synthesis
ontology: BP
definition:
The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or replication complex to insert a defined nucleotide across the lesion. This process does not remove the replication-blocking lesions but does not causes an increase in the endogenous mutation level. For S. cerevisiae, RAD30 encodes DNA polymerase eta, which incorporates two adenines. When incorporated across a thymine-thymine dimer, it does not increase the endogenous mutation level.


go_id: GO:0070989
term: oxidative demethylation
ontology: BP
definition:
The process of removing one or more methyl groups from a molecule, involving the oxidation (i.e. electron loss) of one or more atoms in the substrate.


go_id: GO:0070991
term: medium-chain-acyl-CoA dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: a medium-chain 2,3-saturated fatty acyl-CoA + H+ + oxidized [electron-transfer flavoprotein] = a medium-chain trans-(2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. A medium chain fatty acid is any fatty acid with a chain length of between C6 and C12.


go_id: GO:0070992
term: translation initiation complex
ontology: CC
definition:
A ribonucleoprotein complex that contains a ribosome, mRNA, and initiator tRNA; the functional ribosome is at the AUG, with the methionyl/formyl-methionyl-tRNA positioned at the P site.


go_id: GO:0070993
term: translation preinitiation complex
ontology: CC
definition:
A ribonucleoprotein complex that contains the small ribosomal subunit, a translation initiation ternary complex (i.e. an initiator tRNA, GTP, and an IF2 or eIF2 complex), and an mRNA.


go_id: GO:0070994
term: detection of oxidative stress
ontology: BP
definition:
The series of events in which a stimulus indicating oxidative stress is received and converted into a molecular signal.


go_id: GO:0070995
term: NADPH oxidation
ontology: BP
definition:
A metabolic process that results in the oxidation of reduced nicotinamide adenine dinucleotide, NADPH, to the oxidized form, NADP.


go_id: GO:0070998
term: sensory perception of gravity
ontology: BP
definition:
The series of events required for an organism to receive a gravitational stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.


go_id: GO:0070999
term: detection of mechanical stimulus involved in sensory perception of gravity
ontology: BP
definition:
The series of events involved in the perception of gravity in which a sensory mechanical stimulus is received and converted into a molecular signal.


go_id: GO:0071000
term: response to magnetism
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnetic stimulus.


go_id: GO:0071001
term: U4/U6 snRNP
ontology: CC
definition:
A ribonucleoprotein complex that contains the extensively base paired small nuclear RNAs U4 and U6, a heptameric ring of Sm proteins associated with U4, the Lsm2-8 heptameric ring complex associated with U6, as well as several proteins that are unique to the U4 snRNP or U6 snRNPs, some of which remain associated with the U4/U6 snRNA both while the U4 snRNP is free or assembled into a series of spliceosomal complexes.


go_id: GO:0071002
term: U4atac/U6atac snRNP
ontology: CC
definition:
A ribonucleoprotein complex that contains the extensively base paired small nuclear RNAs U4atac and U6atac, a heptameric ring of Sm proteins associated with U4atac, the Lsm2-8 heptameric ring complex associated with U6atac, as well as several proteins that are unique to the U4atac snRNP or U6atac snRNPs, some of which remain associated with the U4atac/U6atac snRNA both while the U4atac snRNP is free or assembled into a series of spliceosomal complexes.


go_id: GO:0071003
term: penta-snRNP complex
ontology: CC
definition:
A ribonucleoprotein complex that is formed by the association of the U1, U2, U4/U6 and U5 small nuclear ribonucleoproteins.


go_id: GO:0071004
term: U2-type prespliceosome
ontology: CC
definition:
A spliceosomal complex that is formed by association of the 5' splice site with the U1 snRNP, while the branch point sequence is recognized by the U2 snRNP. The prespliceosome includes many proteins in addition to those found in the U1 and U2 snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation.


go_id: GO:0071005
term: U2-type precatalytic spliceosome
ontology: CC
definition:
A spliceosomal complex that is formed by the recruitment of the preassembled U4/U6.U5 tri-snRNP to the prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the U1, U2 and U4/U6.U5 snRNPs.


go_id: GO:0071006
term: U2-type catalytic step 1 spliceosome
ontology: CC
definition:
A spliceosomal complex that is formed by the displacement of the U1 and U4 snRNPs from the precatalytic spliceosome; the U2, U5 and U6 snRNPs remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the U2, and U5 and U6 snRNPs.


go_id: GO:0071007
term: U2-type catalytic step 2 spliceosome
ontology: CC
definition:
A spliceosomal complex that contains the U2, U5 and U6 snRNPs bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the U2, U5 and U6 snRNPs.


go_id: GO:0071008
term: U2-type post-mRNA release spliceosomal complex
ontology: CC
definition:
A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and the U2, U5 and U6 snRNPs.


go_id: GO:0071010
term: prespliceosome
ontology: CC
definition:
A spliceosomal complex that is formed by association of the 5' splice site and the branch point sequence with specific snRNPs. The prespliceosome includes many proteins in addition to those found in the bound snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation. Prespliceosome complexes are not active for splicing, but are instead an early step in the assembly of a spliceosomal complex.


go_id: GO:0071011
term: precatalytic spliceosome
ontology: CC
definition:
A spliceosomal complex that is formed by the recruitment of a preassembled U5-containing tri-snRNP to the prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the associated snRNPs.


go_id: GO:0071012
term: catalytic step 1 spliceosome
ontology: CC
definition:
A spliceosomal complex that is formed by the displacement of the two snRNPs from the precatalytic spliceosome; three snRNPs including U5 remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the associated snRNPs.


go_id: GO:0071013
term: catalytic step 2 spliceosome
ontology: CC
definition:
A spliceosomal complex that contains three snRNPs, including U5, bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the associated snRNPs.


go_id: GO:0071014
term: post-mRNA release spliceosomal complex
ontology: CC
definition:
A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and three snRNPs, including U5.


go_id: GO:0071015
term: U12-type prespliceosome
ontology: CC
definition:
A spliceosomal complex that is formed by the cooperative binding of the heterodimeric U11/U12 snRNP to the 5' splice site and the branch point sequence. The U12-type prespliceosome includes many proteins in addition to those found in the U11/U12 heterodimeric snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation.


go_id: GO:0071016
term: U12-type precatalytic spliceosome
ontology: CC
definition:
A spliceosomal complex that is formed by the recruitment of the preassembled U4atac/U6atac.U5 tri-snRNP to the U12-type prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the U11, U12 and U4atac/U6atac.U5 snRNPs.


go_id: GO:0071017
term: U12-type catalytic step 1 spliceosome
ontology: CC
definition:
A spliceosomal complex that is formed by the displacement of the U11 and U4atac snRNPs from the precatalytic spliceosome; the U12, U5 and U6atac snRNPs remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the U12, and U5 and U6atac snRNPs.


go_id: GO:0071018
term: U12-type catalytic step 2 spliceosome
ontology: CC
definition:
A spliceosomal complex that contains the U12, U5 and U6atac snRNPs bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the U12, U5 and U6atac snRNPs.


go_id: GO:0071019
term: U12-type post-mRNA release spliceosomal complex
ontology: CC
definition:
A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and the U12, U5 and U6atac snRNPs.


go_id: GO:0071020
term: post-spliceosomal complex
ontology: CC
definition:
A spliceosomal complex that is formed following the second splicing event and contains the spliced product, the excised intron, and three snRNPs, including U5.


go_id: GO:0071021
term: U2-type post-spliceosomal complex
ontology: CC
definition:
A spliceosomal complex that is formed following the second splicing event and contains the spliced product, the excised intron, and three snRNPs, U5, U2 and U6.


go_id: GO:0071022
term: U12-type post-spliceosomal complex
ontology: CC
definition:
A spliceosomal complex that is formed following the second splicing event and contains the spliced product, the excised intron, and three snRNPs, U5, U12 and U6atac.


go_id: GO:0071023
term: trans spliceosomal complex
ontology: CC
definition:
A spliceosomal complex that forms during the addition of a specific spliced leader (SL) sequence to the 5'-end of a messenger RNA primary transcript, a process which occurs in a number of eukaryotic organisms, including trypanosomatid protozoans, euglenoids, nematodes, trematodes, and chordates.


go_id: GO:0071026
term: cytoplasmic RNA surveillance
ontology: BP
definition:
The set of processes involved in identifying and degrading defective or aberrant RNAs within the cytoplasm.


go_id: GO:0071029
term: nuclear ncRNA surveillance
ontology: BP
definition:
The set of processes involved in identifying and degrading defective or aberrant ncRNAs within the nucleus.


go_id: GO:0071030
term: nuclear mRNA surveillance of spliceosomal pre-mRNA splicing
ontology: BP
definition:
The set of processes involved in identifying and degrading incorrectly spliced pre-mRNAs within the nucleus.


go_id: GO:0071031
term: nuclear mRNA surveillance of mRNA 3'-end processing
ontology: BP
definition:
The set of processes involved in identifying and degrading mRNAs with incorrectly formed 3'-ends within the nucleus.


go_id: GO:0071032
term: nuclear mRNA surveillance of mRNP export
ontology: BP
definition:
The set of processes involved in identifying and degrading incorrectly formed or aberrant nuclear mRNPs docked at the nuclear pore complex prior to export to the cytoplasm.


go_id: GO:0071034
term: CUT catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of cryptic unstable transcripts (CUTs).


go_id: GO:0071035
term: nuclear polyadenylation-dependent rRNA catabolic process
ontology: BP
definition:
The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a ribosomal RNA (rRNA) molecule, including RNA fragments released as part of processing the primary transcript into multiple mature rRNA species, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target rRNA.


go_id: GO:0071036
term: nuclear polyadenylation-dependent snoRNA catabolic process
ontology: BP
definition:
The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a small nucleolar RNA (snoRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target snoRNA.


go_id: GO:0071037
term: nuclear polyadenylation-dependent snRNA catabolic process
ontology: BP
definition:
The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a small nuclear RNA (snRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target snRNA.


go_id: GO:0071038
term: nuclear polyadenylation-dependent tRNA catabolic process
ontology: BP
definition:
The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of an aberrant or incorrectly modified transfer RNA (tRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target tRNA.


go_id: GO:0071039
term: nuclear polyadenylation-dependent CUT catabolic process
ontology: BP
definition:
The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a cryptic unstable transcript (CUT), initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target CUT.


go_id: GO:0071040
term: nuclear polyadenylation-dependent antisense transcript catabolic process
ontology: BP
definition:
The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of an antisense transcript, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target antisense transcript.


go_id: GO:0071041
term: antisense RNA transcript catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of antisense transcripts, i.e. transcripts that were produced from the antisense strand of a gene that produces a gene product and which often have a regulatory effect on the transcription of that gene product.


go_id: GO:0071042
term: nuclear polyadenylation-dependent mRNA catabolic process
ontology: BP
definition:
The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target mRNA.


go_id: GO:0071043
term: CUT metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving cryptic unstable transcripts (CUTs), which are transcribed from intergenic regions. Many intergenic regions are heavily transcribed, but the transcripts are rarely detected due to rapid degradation by the nuclear exosome.


go_id: GO:0071045
term: nuclear histone mRNA catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of histone messenger RNA (mRNA) within the nucleus.


go_id: GO:0071046
term: nuclear polyadenylation-dependent ncRNA catabolic process
ontology: BP
definition:
The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a noncoding RNA (ncRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target ncRNA.


go_id: GO:0071047
term: polyadenylation-dependent mRNA catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target mRNA.


go_id: GO:0071050
term: sno(s)RNA polyadenylation
ontology: BP
definition:
The enzymatic addition of a sequence of adenylyl residues at the 3' end of snoRNA class molecule (referred to as an sRNA in Archaea). In eukaryotes, this occurs in conjunction with termination of transcription of precursor snoRNA molecules and may occur post-transcriptionally on incorrectly processed molecules targeted for degradation.


go_id: GO:0071051
term: polyadenylation-dependent snoRNA 3'-end processing
ontology: BP
definition:
Any process involved in forming the mature 3' end of a snoRNA molecule linked to prior polyadenylation of the 3'-end of the precursor snoRNA.


go_id: GO:0071052
term: alpha9-beta1 integrin-ADAM1 complex
ontology: CC
definition:
A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM1.


go_id: GO:0071053
term: alpha9-beta1 integrin-ADAM2 complex
ontology: CC
definition:
A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM2.


go_id: GO:0071054
term: alpha9-beta1 integrin-ADAM3 complex
ontology: CC
definition:
A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM3.


go_id: GO:0071055
term: alpha9-beta1 integrin-ADAM9 complex
ontology: CC
definition:
A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM9.


go_id: GO:0071056
term: alpha9-beta1 integrin-ADAM15 complex
ontology: CC
definition:
A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM15.


go_id: GO:0071057
term: alphav-beta3 integrin-ADAM15 complex
ontology: CC
definition:
A protein complex that consists of an alphav-beta3 integrin complex bound to the transmembrane metallopeptidase ADAM15.


go_id: GO:0071063
term: sensory perception of wind
ontology: BP
definition:
The series of events required for an organism to receive sensory mechanical stimulus resulting from air flow, convert it to a molecular signal, and recognize and characterize the signal.


go_id: GO:0071065
term: alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex
ontology: CC
definition:
A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular cell adhesion molecule-1.


go_id: GO:0071066
term: detection of mechanical stimulus involved in sensory perception of wind
ontology: BP
definition:
The series of events involved in the perception of wind in which a mechanical stimulus is received and converted into a molecular signal.


go_id: GO:0071067
term: alphav-beta3 integrin-ADAM23 complex
ontology: CC
definition:
A protein complex that consists of an alphav-beta3 integrin complex bound to the transmembrane metallopeptidase ADAM23.


go_id: GO:0071068
term: alpha9-beta1 integrin-ADAM12 complex
ontology: CC
definition:
A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM12.


go_id: GO:0071071
term: regulation of phospholipid biosynthetic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids.


go_id: GO:0071072
term: negative regulation of phospholipid biosynthetic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids.


go_id: GO:0071073
term: positive regulation of phospholipid biosynthetic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids.


go_id: GO:0071074
term: eukaryotic initiation factor eIF2 binding
ontology: MF
definition:
Binding to eukaryotic initiation factor eIF2, a protein complex involved in the initiation of ribosome-mediated translation.


go_id: GO:0071075
term: CUGBP1-eIF2 complex
ontology: CC
definition:
A protein complex that contains the eukaryotic translation initiation factor 2 complex (EIF2), CUG binding protein 1, and several endoplasmic reticulum proteins; the complex is involved in the regulation of translation.


go_id: GO:0071078
term: fibronectin-tissue transglutaminase complex
ontology: CC
definition:
A protein complex that consists of fibronectin bound to tissue transglutaminase, and is involved in cell adhesion.


go_id: GO:0071079
term: alpha2-beta1 integrin-chondroadherin complex
ontology: CC
definition:
A protein complex that consists of an alpha2-beta1 integrin complex bound to the cartilage matrix protein chondroadherin.


go_id: GO:0071080
term: alpha3-beta1 integrin-basigin complex
ontology: CC
definition:
A protein complex that consists of an alpha3-beta1 integrin complex bound to the cell surface protein basigin.


go_id: GO:0071082
term: alpha9-beta1 integrin-tenascin complex
ontology: CC
definition:
A protein complex that consists of an alpha9-beta1 integrin complex bound to the extracellular matrix protein tenascin.


go_id: GO:0071083
term: alphaV-beta3 integrin-CD47-FCER2 complex
ontology: CC
definition:
A protein complex that consists of an alphaV-beta3 integrin complex bound to the cell surface protein CD47 and the low-affinity immunoglobulin epsilon Fc receptor (FCER2).


go_id: GO:0071084
term: alpha2-beta1 integrin-CD47 complex
ontology: CC
definition:
A protein complex that consists of an alpha2-beta1 integrin complex bound to the cell surface protein CD47.


go_id: GO:0071085
term: alphaIIb-beta3 integrin-CD9 complex
ontology: CC
definition:
A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface protein CD9.


go_id: GO:0071086
term: alphaIIb-beta3 integrin-CD9-CD47-platelet glycoprotein Ib complex
ontology: CC
definition:
A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface proteins CD9 and CD47, and the heterodimeric platelet glycoprotein Ib.


go_id: GO:0071088
term: alpha5-beta1 integrin-tissue transglutaminase complex
ontology: CC
definition:
A protein complex that consists of an alpha5-beta1 integrin complex bound to tissue transglutaminase.


go_id: GO:0071089
term: alphaV-beta3 integrin-tissue transglutaminase complex
ontology: CC
definition:
A protein complex that consists of an alphaV-beta3 integrin complex bound to tissue transglutaminase.


go_id: GO:0071090
term: alphaIIb-beta3 integrin-fibronectin-tissue transglutaminase complex
ontology: CC
definition:
A protein complex that consists of an alphaIIb-beta3 integrin complex bound to fibronectin and tissue transglutaminase.


go_id: GO:0071091
term: alpha1-beta1 integrin-tissue transglutaminase complex
ontology: CC
definition:
A protein complex that consists of an alpha1-beta1 integrin complex bound to tissue transglutaminase.


go_id: GO:0071092
term: alpha3-beta1 integrin-tissue transglutaminase complex
ontology: CC
definition:
A protein complex that consists of an alpha3-beta1 integrin complex bound to tissue transglutaminase.


go_id: GO:0071093
term: alpha5-beta1 integrin-fibronectin-tissue transglutaminase complex
ontology: CC
definition:
A protein complex that consists of an alpha5-beta1 integrin complex bound to fibronectin and tissue transglutaminase.


go_id: GO:0071094
term: alpha6-beta4 integrin-CD9 complex
ontology: CC
definition:
A protein complex that consists of an alpha6-beta4 integrin complex bound to the cell surface protein CD9.


go_id: GO:0071097
term: alphaV-beta3 integrin-paxillin-Pyk2 complex
ontology: CC
definition:
A protein complex that consists of an alphaV-beta3 integrin complex bound to paxillin and the FAK-related kinase Pyk2.


go_id: GO:0071098
term: alpha6-beta4 integrin-Fyn complex
ontology: CC
definition:
A protein complex that consists of an alpha6-beta4 integrin complex bound to the Src family tyrosine kinase Fyn.


go_id: GO:0071099
term: alphaV-beta6 integrin-TGFbeta-3 complex
ontology: CC
definition:
A protein complex that consists of an alphaV-beta6 integrin complex bound to transforming growth factor beta-3 (TGFbeta-3).


go_id: GO:0071100
term: alphaV-beta8 integrin-MMP14-TGFbeta-1 complex
ontology: CC
definition:
A protein complex that consists of an alphaV-beta8 integrin complex bound to matrix metalloproteinase 14 and transforming growth factor beta-1 (TGFbeta-1).


go_id: GO:0071101
term: alpha4-beta1 integrin-JAM2 complex
ontology: CC
definition:
A protein complex that consists of an alpha4-beta1 integrin complex bound to the cell adhesion molecule JAM2.


go_id: GO:0071103
term: DNA conformation change
ontology: BP
definition:
A cellular process that results in a change in the spatial configuration of a DNA molecule. A conformation change can bend DNA, or alter the, twist, writhe, or linking number of a DNA molecule.


go_id: GO:0071104
term: response to interleukin-9
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-9 stimulus.


go_id: GO:0071105
term: response to interleukin-11
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-11 stimulus.


go_id: GO:0071107
term: response to parathyroid hormone
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a parathyroid hormone stimulus.


go_id: GO:0071108
term: protein K48-linked deubiquitination
ontology: BP
definition:
A protein deubiquitination process in which a K48-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is removed from a protein.


go_id: GO:0071109
term: superior temporal gyrus development
ontology: BP
definition:
The process whose specific outcome is the progression of the superior temporal gyrus over time, from its formation to the mature structure. The superior temporal gyrus is a portion of the cerebral cortex that extends from the lateral sulcus to the superior temporal sulcus.


go_id: GO:0071111
term: cyclic-guanylate-specific phosphodiesterase activity
ontology: MF
definition:
Catalysis of the reaction: cyclic di-3',5'-guanylate + H(2)O = 5'-phosphoguanylyl(3'->5')guanosine + H(+).


go_id: GO:0071112
term: alpha4-beta4 integrin-EMILIN-1 complex
ontology: CC
definition:
A protein complex that consists of an alpha4-beta4 integrin complex bound to EMILIN-1 (ElastinMicrofibril Interface Located ProteIN).


go_id: GO:0071113
term: alphaIIb-beta3 integrin-ICAM-4 complex
ontology: CC
definition:
A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell adhesion molecule ICAM-4.


go_id: GO:0071114
term: alphaV-beta3 integrin-tumstatin complex
ontology: CC
definition:
A protein complex that consists of an alphaV-beta3 integrin complex bound to tumstatin, the NC1 domain of the alpha3 chain of type IV collagen.


go_id: GO:0071115
term: alpha5-beta1 integrin-endostatin complex
ontology: CC
definition:
A protein complex that consists of an alpha5-beta1 integrin complex bound to endostatin, the NC1 domain of the alpha1 chain of type XVIII collagen.


go_id: GO:0071116
term: alpha6-beta1 integrin-CYR61 complex
ontology: CC
definition:
A protein complex that consists of an alpha6-beta1 integrin complex bound to CYR61, a cysteine-rich protein involved in angiogenesis.


go_id: GO:0071117
term: alpha5-beta1 integrin-fibronectin-NOV complex
ontology: CC
definition:
A protein complex that consists of an alpha5-beta1 integrin complex bound to fibronectin and the extracellular matrix protein NOV.


go_id: GO:0071118
term: alphaV-beta3 integrin-NOV complex
ontology: CC
definition:
A protein complex that consists of an alphaV-beta3 integrin complex bound to the extracellular matrix protein NOV.


go_id: GO:0071119
term: alpha7-beta1 integrin-nicotinamide riboside kinase complex
ontology: CC
definition:
A protein complex that consists of an alpha7-beta1 integrin complex bound to nicotinamide riboside kinase 2 (also known as muscle integrin binding protein, MIBP).


go_id: GO:0071120
term: alpha4-beta1 integrin-CD47 complex
ontology: CC
definition:
A protein complex that consists of an alpha4-beta1 integrin complex bound to the cell surface antigen CD47.


go_id: GO:0071121
term: alpha9-beta1 integrin-VEGF-D complex
ontology: CC
definition:
A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular endothelial growth factor D.


go_id: GO:0071122
term: alpha9-beta1 integrin-VEGF-A complex
ontology: CC
definition:
A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular endothelial growth factor A.


go_id: GO:0071123
term: alpha9-beta1 integrin-VEGF-C complex
ontology: CC
definition:
A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular endothelial growth factor C.


go_id: GO:0071124
term: alpha1-beta1 integrin-tyrosine-protein phosphatase non-receptor type 2 complex
ontology: CC
definition:
A protein complex that consists of an alpha1-beta1 integrin complex bound to tyrosine-protein phosphatase non-receptor type 2.


go_id: GO:0071125
term: alphaV-beta3 integrin-EGFR complex
ontology: CC
definition:
A protein complex that consists of an alphaV-beta3 integrin complex bound to epidermal growth factor receptor.


go_id: GO:0071129
term: alphaV-beta3 integrin-LPP3 complex
ontology: CC
definition:
A protein complex that consists of an alphaV-beta3 integrin complex bound to lipid phosphate phosphohydrolase-3.


go_id: GO:0071130
term: alpha5-beta1 integrin-LPP3 complex
ontology: CC
definition:
A protein complex that consists of an alpha5-beta1 integrin complex bound to lipid phosphate phosphohydrolase-3.


go_id: GO:0071132
term: alphaX-beta2 integrin-ICAM-4 complex
ontology: CC
definition:
A protein complex that consists of an alphaX-beta2 integrin complex bound to intercellular adhesion molecule 4.


go_id: GO:0071133
term: alpha9-beta1 integrin-ADAM8 complex
ontology: CC
definition:
A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM8.


go_id: GO:0071137
term: alphaV-beta3 integrin-CD98 complex
ontology: CC
definition:
A protein complex that consists of an alphaV-beta3 integrin complex bound to the cell surface antigen CD98.


go_id: GO:0071138
term: alpha5-beta5-fibronectin-SFRP2 complex
ontology: CC
definition:
A protein complex that consists of an alpha5-beta5 integrin complex bound to fibronectin and secreted frizzled-related protein 2.


go_id: GO:0071139
term: resolution of recombination intermediates
ontology: BP
definition:
The cleavage and rejoining of intermediates, such as Holliday junctions, formed during DNA recombination to produce two intact molecules in which genetic material has been exchanged.


go_id: GO:0071140
term: resolution of mitotic recombination intermediates
ontology: BP
definition:
The cleavage and rejoining of intermediates, mitotic recombination to produce two intact molecules in which genetic material has been exchanged.


go_id: GO:0071141
term: SMAD protein complex
ontology: CC
definition:
A protein complex that consists of only SMAD proteins; may be homomeric or heteromeric. Heteromeric complexes act as transcription factors while homomeric complexes exist but are transcriptionally inactive. Hetero- versus homotrimerization is largely enthalpy driven.


go_id: GO:0071142
term: homomeric SMAD protein complex
ontology: CC
definition:
A protein complex composed of a single type of SMAD family proteins. In the absence of Smad4, phosphorylation of R-SMADs results in their homotrimerization. However, these complexes do not appear to import into the nucleus and are assumed to be transcriptionally inactive.


go_id: GO:0071144
term: heteromeric SMAD protein complex
ontology: CC
definition:
A protein complex composed of SMAD family proteins, a transcription factor complex which binds to the promoters of target genes and recruits co-activators and histone acetyltransferases, facilitating transcription. Phosphorylation of the non-SMAD4 subunit(s) enables binding of SMAD4 to form heteromeric complexes that enter the nucleus to initiate gene transcription. DNA-binding specificity is conferred by other transcription factors binding to SMAD complexes. Interactions with coactivators or corepressors modulate their transcriptional activity. Can be heterotrimeric or heterodimeric.


go_id: GO:0071152
term: G-protein alpha(q)-synembrin complex
ontology: CC
definition:
A protein complex formed by the association of the guanine nucleotide exchange factor synembrin with the alpha(q) subunit of a heterotrimeric G protein.


go_id: GO:0071153
term: G-protein alpha(o)-synembrin complex
ontology: CC
definition:
A protein complex formed by the association of the guanine nucleotide exchange factor synembrin with the alpha(o) subunit of a heterotrimeric G protein.


go_id: GO:0071154
term: G-protein alpha(i)1-synembrin complex
ontology: CC
definition:
A protein complex formed by the association of the guanine nucleotide exchange factor synembrin with the alpha(i)1 subunit of a heterotrimeric G protein.


go_id: GO:0071155
term: G-protein alpha(13)-synembrin complex
ontology: CC
definition:
A protein complex formed by the association of the guanine nucleotide exchange factor synembrin with the alpha(13) subunit of a heterotrimeric G protein.


go_id: GO:0071159
term: NF-kappaB complex
ontology: CC
definition:
A protein complex that consists of a homo- or heterodimer of members of a family of structurally related proteins that contain a conserved N-terminal region called the Rel homology domain (RHD). In the nucleus, NF-kappaB complexes act as transcription factors. In unstimulated cells, NF-kappaB dimers are sequestered in the cytoplasm by IkappaB monomers; signals that induce NF-kappaB activity cause degradation of IkappaB, allowing NF-kappaB dimers to translocate to the nucleus and induce gene expression.


go_id: GO:0071160
term: cyanophycin synthetase activity (L-aspartate-adding)
ontology: MF
definition:
Catalysis of the reaction: ATP + [L-Asp(4-L-Arg)]n + L-Asp = ADP + phosphate + [L-Asp(4-L-Arg)]n-L-Asp.


go_id: GO:0071161
term: cyanophycin synthetase activity (L-arginine-adding)
ontology: MF
definition:
Catalysis of the reaction: ATP + [L-Asp(4-L-Arg)]n-L-Asp + L-arginine = ADP + phosphate + [L-Asp(4-L-Arg)]n+1.


go_id: GO:0071162
term: CMG complex
ontology: CC
definition:
A protein complex that contains the GINS complex, Cdc45p, and the heterohexameric MCM complex, and that is involved in unwinding DNA during replication.


go_id: GO:0071163
term: DNA replication preinitiation complex assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form the DNA replication preinitiation complex, a protein-DNA complex that is assembled at DNA replication origins immediately prior to the initiation of DNA replication. The complex consists of proteins that initiate the DNA binding, melt the helix and enable helicase activity.


go_id: GO:0071164
term: RNA trimethylguanosine synthase activity
ontology: MF
definition:
Catalysis of two successive methyl transfer reactions from AdoMet to the N-2 atom of guanosine, thereby converting 7-methylguanosine in an RNA cap to 2,2,7 trimethylguanosine.


go_id: GO:0071165
term: GINS complex assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form a GINS complex, a heterotetrameric protein complex that associates with DNA replication origins and replication forks.


go_id: GO:0071166
term: ribonucleoprotein complex localization
ontology: BP
definition:
Any process in which a ribonucleoprotein complex is transported to, or maintained in, a specific location within a cell.


go_id: GO:0071168
term: protein localization to chromatin
ontology: BP
definition:
Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into chromatin.


go_id: GO:0071171
term: site-specific DNA replication termination at RTS1 barrier
ontology: BP
definition:
A DNA replication termination process that takes place at the RTS1 termination site in the mating type locus, in a specific direction required for subsequent imprinting and mating-type switching.


go_id: GO:0071173
term: spindle assembly checkpoint signaling
ontology: BP
definition:
A signaling process that delays the metaphase/anaphase transition until the spindle is correctly assembled and chromosomes are attached to the spindle.


go_id: GO:0071174
term: mitotic spindle checkpoint signaling
ontology: BP
definition:
A signaling process that contributes to a mitotic cell cycle checkpoint that originates from the spindle and delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and oriented, the completion of anaphase until chromosomes are attached to the spindle, or mitotic exit and cytokinesis when the spindle does not form.


go_id: GO:0071175
term: MAML2-RBP-Jkappa-ICN1 complex
ontology: CC
definition:
A protein complex that consists of the intracellular domain of Notch1 (ICN1), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-2 (MAML2); the complex is involved in transcriptional activation in response to Notch-mediated signaling.


go_id: GO:0071176
term: MAML2-RBP-Jkappa-ICN2 complex
ontology: CC
definition:
A protein complex that consists of the intracellular domain of Notch2 (ICN2), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-2 (MAML2); the complex is involved in transcriptional activation in response to Notch-mediated signaling.


go_id: GO:0071177
term: MAML2-RBP-Jkappa-ICN3 complex
ontology: CC
definition:
A protein complex that consists of the intracellular domain of Notch3 (ICN3), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-2 (MAML2); the complex is involved in transcriptional activation in response to Notch-mediated signaling.


go_id: GO:0071178
term: MAML2-RBP-Jkappa-ICN4 complex
ontology: CC
definition:
A protein complex that consists of the intracellular domain of Notch4 (ICN4), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-2 (MAML2); the complex is involved in transcriptional activation in response to Notch-mediated signaling.


go_id: GO:0071179
term: MAML3-RBP-Jkappa-ICN1 complex
ontology: CC
definition:
A protein complex that consists of the intracellular domain of Notch1 (ICN1), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling.


go_id: GO:0071180
term: MAML3-RBP-Jkappa-ICN2 complex
ontology: CC
definition:
A protein complex that consists of the intracellular domain of Notch2 (ICN2), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling.


go_id: GO:0071181
term: MAML3-RBP-Jkappa-ICN3 complex
ontology: CC
definition:
A protein complex that consists of the intracellular domain of Notch3 (ICN3), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling.


go_id: GO:0071182
term: MAML3-RBP-Jkappa-ICN4 complex
ontology: CC
definition:
A protein complex that consists of the intracellular domain of Notch4 (ICN4), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling.


go_id: GO:0071183
term: protocadherin-alpha-protocadherin-gamma complex
ontology: CC
definition:
A protein complex that contains two cell adhesion molecules, a protocadherin-alpha and a protocadherin-gamma, and is involved in the regulation of protein localization to the plasma membrane.


go_id: GO:0071184
term: protocadherin-alpha-v4-protocadherin-gamma-a1 complex
ontology: CC
definition:
A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-a1, and is involved in the regulation of protein localization to the plasma membrane.


go_id: GO:0071185
term: protocadherin-alpha-v4-protocadherin-gamma-a3 complex
ontology: CC
definition:
A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-a3, and is involved in the regulation of protein localization to the plasma membrane.


go_id: GO:0071186
term: protocadherin-alpha-v4-protocadherin-gamma-b2 complex
ontology: CC
definition:
A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-b2, and is involved in the regulation of protein localization to the plasma membrane.


go_id: GO:0071187
term: protocadherin-alpha-v4-protocadherin-gamma-b4 complex
ontology: CC
definition:
A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-b4, and is involved in the regulation of protein localization to the plasma membrane.


go_id: GO:0071188
term: protocadherin-alpha-v7-protocadherin-gamma-a1 complex
ontology: CC
definition:
A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-a1, and is involved in the regulation of protein localization to the plasma membrane.


go_id: GO:0071189
term: protocadherin-alpha-v7-protocadherin-gamma-a3 complex
ontology: CC
definition:
A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-a3, and is involved in the regulation of protein localization to the plasma membrane.


go_id: GO:0071190
term: protocadherin-alpha-v7-protocadherin-gamma-b2 complex
ontology: CC
definition:
A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-b2, and is involved in the regulation of protein localization to the plasma membrane.


go_id: GO:0071191
term: protocadherin-alpha-v7-protocadherin-gamma-b4 complex
ontology: CC
definition:
A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-b4, and is involved in the regulation of protein localization to the plasma membrane.


go_id: GO:0071192
term: Kv4.2-KChIP1 channel complex
ontology: CC
definition:
A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP1 associated with the channel via interaction with the Kv alpha subunit 4.2.


go_id: GO:0071193
term: Kv4.2-KChIP2 channel complex
ontology: CC
definition:
A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP2 associated with the channel via interaction with the Kv alpha subunit 4.2.


go_id: GO:0071194
term: Kv4.2-KChIP3 channel complex
ontology: CC
definition:
A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP3 associated with the channel via interaction with the Kv alpha subunit 4.2.


go_id: GO:0071195
term: Kv4.2-KChIP4 channel complex
ontology: CC
definition:
A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP4 associated with the channel via interaction with the Kv alpha subunit 4.2.


go_id: GO:0071196
term: Kv4.3-KChIP1 channel complex
ontology: CC
definition:
A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP1 associated with the channel via interaction with the Kv alpha subunit 4.3.


go_id: GO:0071198
term: Kv4.1-DPP6 channel complex
ontology: CC
definition:
A voltage-gated potassium channel complex that contains the peptidase-related protein DPP6 associated with the channel via interaction with the Kv alpha subunit 4.1.


go_id: GO:0071199
term: Kv4.1-DPP10 channel complex
ontology: CC
definition:
A voltage-gated potassium channel complex that contains the peptidase-related protein DPP10 associated with the channel via interaction with the Kv alpha subunit 4.1.


go_id: GO:0071200
term: Kv4.2-DPP6 channel complex
ontology: CC
definition:
A voltage-gated potassium channel complex that contains the peptidase-related protein DPP6 associated with the channel via interaction with the Kv alpha subunit 4.2.


go_id: GO:0071201
term: Kv4.3-DPP6 channel complex
ontology: CC
definition:
A voltage-gated potassium channel complex that contains the peptidase-related protein DPP6 associated with the channel via interaction with the Kv alpha subunit 4.3.


go_id: GO:0071202
term: Kv4.3-DPP10 channel complex
ontology: CC
definition:
A voltage-gated potassium channel complex that contains the peptidase-related protein DPP10 associated with the channel via interaction with the Kv alpha subunit 4.3.


go_id: GO:0071203
term: WASH complex
ontology: CC
definition:
A protein complex that localizes at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization. In human, the WASH complex is composed of F-actin-capping protein subunits alpha and beta, WASH1, FAM21, KIAA1033, KIAA0196 and CCDC53.


go_id: GO:0071204
term: histone pre-mRNA 3'end processing complex
ontology: CC
definition:
A ribonucleoprotein that binds to specific sites in, and is required for cleavage of, the 3'-end of histone pre-mRNAs. The complex contains the U7 snRNP and additional proteins, including the stem-loop binding protein (SLBP) and the exonuclease 3'hExo/Eri-1.


go_id: GO:0071205
term: protein localization to juxtaparanode region of axon
ontology: BP
definition:
Any process in which a protein is transported to, or maintained at, the juxtaparanode region of an axon.


go_id: GO:0071210
term: protein insertion into membrane raft
ontology: BP
definition:
The process in which a protein is incorporated into a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes.


go_id: GO:0071211
term: protein targeting to vacuole involved in autophagy
ontology: BP
definition:
The process of directing proteins towards the vacuole using signals contained within the protein, occurring as part of autophagy, the process in which cells digest parts of their own cytoplasm.


go_id: GO:0071213
term: cellular response to 1-aminocyclopropane-1-carboxylic acid
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-aminocyclopropane-1-carboxylic acid stimulus.


go_id: GO:0071214
term: cellular response to abiotic stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus.


go_id: GO:0071215
term: cellular response to abscisic acid stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.


go_id: GO:0071216
term: cellular response to biotic stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism.


go_id: GO:0071217
term: cellular response to external biotic stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things.


go_id: GO:0071218
term: cellular response to misfolded protein
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a misfolded protein stimulus.


go_id: GO:0071219
term: cellular response to molecule of bacterial origin
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of bacterial origin such as peptides derived from bacterial flagellin.


go_id: GO:0071220
term: cellular response to bacterial lipoprotein
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipoprotein stimulus.


go_id: GO:0071221
term: cellular response to bacterial lipopeptide
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipopeptide stimulus.


go_id: GO:0071222
term: cellular response to lipopolysaccharide
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.


go_id: GO:0071223
term: cellular response to lipoteichoic acid
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoteichoic acid stimulus; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.


go_id: GO:0071224
term: cellular response to peptidoglycan
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptidoglycan stimulus. Peptidoglycan is a bacterial cell wall macromolecule.


go_id: GO:0071225
term: cellular response to muramyl dipeptide
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muramyl dipeptide stimulus. Muramyl dipeptide is derived from peptidoglycan.


go_id: GO:0071226
term: cellular response to molecule of fungal origin
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of fungal origin such as chito-octamer oligosaccharide.


go_id: GO:0071227
term: cellular response to molecule of oomycetes origin
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of oomycetes origin.


go_id: GO:0071228
term: cellular response to tumor cell
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a tumor cell.


go_id: GO:0071229
term: cellular response to acid chemical
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of the dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form.


go_id: GO:0071230
term: cellular response to amino acid stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.


go_id: GO:0071231
term: cellular response to folic acid
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a folic acid stimulus.


go_id: GO:0071232
term: cellular response to histidine
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histidine stimulus.


go_id: GO:0071233
term: cellular response to leucine
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leucine stimulus.


go_id: GO:0071234
term: cellular response to phenylalanine
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phenylalanine stimulus.


go_id: GO:0071235
term: cellular response to proline
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a proline stimulus.


go_id: GO:0071236
term: cellular response to antibiotic
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.


go_id: GO:0071237
term: cellular response to bacteriocin
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacteriocin stimulus. A bacteriocin is a protein substance released by certain bacteria that kills but does not lyse closely related strains of bacteria. Specific bacteriocins attach to specific receptors on cell walls and induce specific metabolic block, e.g. cessation of nucleic acid or protein synthesis of oxidative phosphorylation.


go_id: GO:0071238
term: cellular response to brefeldin A
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brefeldin A stimulus.


go_id: GO:0071239
term: cellular response to streptomycin
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a streptomycin stimulus. Streptomycin is a commonly used antibiotic in cell culture media which acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome.


go_id: GO:0071240
term: cellular response to food
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a food stimulus; food is anything which, when taken into the body, serves to nourish or build up the tissues or to supply body heat.


go_id: GO:0071241
term: cellular response to inorganic substance
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus.


go_id: GO:0071242
term: cellular response to ammonium ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus.


go_id: GO:0071243
term: cellular response to arsenic-containing substance
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides.


go_id: GO:0071244
term: cellular response to carbon dioxide
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus.


go_id: GO:0071245
term: cellular response to carbon monoxide
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon monoxide (CO) stimulus.


go_id: GO:0071246
term: cellular response to chlorate
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chlorate stimulus.


go_id: GO:0071247
term: cellular response to chromate
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chromate stimulus.


go_id: GO:0071248
term: cellular response to metal ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus.


go_id: GO:0071249
term: cellular response to nitrate
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrate stimulus.


go_id: GO:0071250
term: cellular response to nitrite
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrite stimulus.


go_id: GO:0071251
term: cellular response to silicon dioxide
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silicon dioxide stimulus.


go_id: GO:0071252
term: cellular response to sulfur dioxide
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sulfur dioxide (SO2) stimulus.


go_id: GO:0071254
term: cytoplasmic U snRNP body
ontology: CC
definition:
A ribonucleoprotein complex that can be visualized as a focus in the cytoplasm, and contains uridine-rich small nuclear ribonucleoproteins (U snRNPs) and essential snRNP assembly factors. These U bodies are invariably found in association with P bodies.


go_id: GO:0071255
term: Cvt vesicle assembly
ontology: BP
definition:
A vesicle organization process that takes place as part of the Cvt pathway, and results in the formation of a double membrane-bounded cytosolic structure that sequesters precursor aminopeptidase I (prAPI).


go_id: GO:0071256
term: translocon complex
ontology: CC
definition:
A protein complex that constitutes a specific site of protein translocation across the endoplasmic reticulum, which involves the signal recognition particle receptor. The complex contains a core heterotrimer of alpha, beta and gamma subunits, and may contain additional proteins.


go_id: GO:0071257
term: cellular response to electrical stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus.


go_id: GO:0071258
term: cellular response to gravity
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gravitational stimulus.


go_id: GO:0071259
term: cellular response to magnetism
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnetic stimulus.


go_id: GO:0071260
term: cellular response to mechanical stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus.


go_id: GO:0071261
term: Ssh1 translocon complex
ontology: CC
definition:
A translocon complex that contains a core heterotrimer of alpha, beta and gamma subunits, and may contain additional proteins (translocon-associated proteins or TRAPs); in budding yeast the core proteins are Ssh1p, Sbh2p, and Sss1p. The Ssh1 translocon complex is involved in the cotranslational pathway of protein transport across the ER membrane, and recognizes proteins bearing strongly hydrophobic signal sequences.


go_id: GO:0071262
term: regulation of translational initiation in response to starvation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of translation initiation, as a result of deprivation of nourishment.


go_id: GO:0071263
term: negative regulation of translational initiation in response to starvation
ontology: BP
definition:
Any process that stops, prevents or reduces the rate of translation initiation, as a result of deprivation of nourishment.


go_id: GO:0071264
term: positive regulation of translational initiation in response to starvation
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of translation initiation, as a result of deprivation of nourishment.


go_id: GO:0071265
term: L-methionine biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of L-methionine, the L-enantiomer of (2S)-2-amino-4-(methylsulfanyl)butanoic acid.


go_id: GO:0071266
term: 'de novo' L-methionine biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of L-methionine, the L-enantiomer of (2S)-2-amino-4-(methylsulfanyl)butanoic acid, from simpler components.


go_id: GO:0071268
term: homocysteine biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of homocysteine, 2-amino-4-sulfanylbutanoic acid.


go_id: GO:0071269
term: L-homocysteine biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of L-homocysteine, the L-enantiomer of 2-amino-4-sulfanylbutanoic acid.


go_id: GO:0071270
term: 1-butanol metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving 1-butanol, an alkyl primary alcohol with the formula C4H10O.


go_id: GO:0071271
term: 1-butanol biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of 1-butanol, an alkyl primary alcohol with the formula C4H10O.


go_id: GO:0071272
term: morphine metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving morphine, 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol. Morphine is a highly potent opiate analgesic psychoactive drug obtained form the opium poppy, Papaver somniferum.


go_id: GO:0071273
term: morphine catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of morphine, 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol. Morphine is a highly potent opiate analgesic psychoactive drug obtained form the opium poppy, Papaver somniferum.


go_id: GO:0071274
term: isoquinoline alkaloid catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of isoquinoline alkaloids, alkaloid compounds that contain bicyclic N-containing aromatic rings and are derived from a 3,4-dihydroxytyramine (dopamine) precursor that undergoes a Schiff base addition with aldehydes of different origin.


go_id: GO:0071275
term: cellular response to aluminum ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aluminum ion stimulus.


go_id: GO:0071276
term: cellular response to cadmium ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.


go_id: GO:0071277
term: cellular response to calcium ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.


go_id: GO:0071278
term: cellular response to cesium ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cesium stimulus.


go_id: GO:0071279
term: cellular response to cobalt ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalt ion stimulus.


go_id: GO:0071280
term: cellular response to copper ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.


go_id: GO:0071281
term: cellular response to iron ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.


go_id: GO:0071282
term: cellular response to iron(II) ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(II) ion stimulus.


go_id: GO:0071283
term: cellular response to iron(III) ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(III) ion stimulus.


go_id: GO:0071284
term: cellular response to lead ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lead ion stimulus.


go_id: GO:0071285
term: cellular response to lithium ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lithium (Li+) ion stimulus.


go_id: GO:0071286
term: cellular response to magnesium ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnesium ion stimulus.


go_id: GO:0071287
term: cellular response to manganese ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a manganese ion stimulus.


go_id: GO:0071288
term: cellular response to mercury ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercury ion stimulus.


go_id: GO:0071289
term: cellular response to nickel ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nickel ion stimulus.


go_id: GO:0071290
term: cellular response to platinum ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platinum stimulus.


go_id: GO:0071291
term: cellular response to selenium ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from selenium ion.


go_id: GO:0071292
term: cellular response to silver ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silver ion stimulus.


go_id: GO:0071293
term: cellular response to tellurium ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tellurium ion stimulus.


go_id: GO:0071294
term: cellular response to zinc ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus.


go_id: GO:0071295
term: cellular response to vitamin
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin stimulus.


go_id: GO:0071296
term: cellular response to biotin
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotin stimulus.


go_id: GO:0071297
term: cellular response to cobalamin
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalamin (vitamin B12) stimulus.


go_id: GO:0071298
term: cellular response to L-ascorbic acid
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-ascorbic acid (vitamin C) stimulus.


go_id: GO:0071299
term: cellular response to vitamin A
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin A stimulus.


go_id: GO:0071300
term: cellular response to retinoic acid
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus.


go_id: GO:0071301
term: cellular response to vitamin B1
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B1 stimulus.


go_id: GO:0071302
term: cellular response to vitamin B2
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B2 stimulus.


go_id: GO:0071303
term: cellular response to vitamin B3
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B3 stimulus.


go_id: GO:0071304
term: cellular response to vitamin B6
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B6 stimulus. Vitamin B6 encompasses pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate.


go_id: GO:0071305
term: cellular response to vitamin D
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin D stimulus.


go_id: GO:0071306
term: cellular response to vitamin E
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin E stimulus.


go_id: GO:0071307
term: cellular response to vitamin K
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin K stimulus.


go_id: GO:0071308
term: cellular response to menaquinone
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a menaquinone (vitamin K2) stimulus.


go_id: GO:0071309
term: cellular response to phylloquinone
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phylloquinone (vitamin K1) stimulus.


go_id: GO:0071310
term: cellular response to organic substance
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.


go_id: GO:0071311
term: cellular response to acetate
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus.


go_id: GO:0071312
term: cellular response to alkaloid
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active.


go_id: GO:0071313
term: cellular response to caffeine
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caffeine stimulus. Caffeine is an alkaloid found in numerous plant species, where it acts as a natural pesticide that paralyzes and kills certain insects feeding upon them.


go_id: GO:0071314
term: cellular response to cocaine
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cocaine stimulus. Cocaine is a crystalline alkaloid obtained from the leaves of the coca plant.


go_id: GO:0071315
term: cellular response to morphine
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a morphine stimulus. Morphine is an opioid alkaloid, isolated from opium, with a complex ring structure.


go_id: GO:0071316
term: cellular response to nicotine
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus.


go_id: GO:0071317
term: cellular response to isoquinoline alkaloid
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isoquinoline alkaloid stimulus. An isoquinoline alkaloid is any member of a group of compounds with the heterocyclic ring structure of benzo(c)pyridine which is a structure characteristic of the group of opium alkaloids.


go_id: GO:0071318
term: cellular response to ATP
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus.


go_id: GO:0071319
term: cellular response to benzoic acid
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benzoic acid stimulus.


go_id: GO:0071320
term: cellular response to cAMP
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus.


go_id: GO:0071321
term: cellular response to cGMP
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cGMP (cyclic GMP, guanosine 3',5'-cyclophosphate) stimulus.


go_id: GO:0071322
term: cellular response to carbohydrate stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus.


go_id: GO:0071323
term: cellular response to chitin
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chitin stimulus.


go_id: GO:0071324
term: cellular response to disaccharide stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disaccharide stimulus.


go_id: GO:0071325
term: cellular response to mannitol stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannitol stimulus.


go_id: GO:0071326
term: cellular response to monosaccharide stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus.


go_id: GO:0071327
term: cellular response to trehalose stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose stimulus.


go_id: GO:0071328
term: cellular response to maltose stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a maltose stimulus.


go_id: GO:0071329
term: cellular response to sucrose stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sucrose stimulus.


go_id: GO:0071330
term: cellular response to trehalose-6-phosphate stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose-6-phosphate stimulus.


go_id: GO:0071331
term: cellular response to hexose stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus.


go_id: GO:0071332
term: cellular response to fructose stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fructose stimulus.


go_id: GO:0071333
term: cellular response to glucose stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.


go_id: GO:0071334
term: cellular response to rhamnose stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rhamnose stimulus.


go_id: GO:0071335
term: hair follicle cell proliferation
ontology: BP
definition:
The multiplication or reproduction of hair follicle cells, resulting in the expansion of a cell population.


go_id: GO:0071339
term: MLL1 complex
ontology: CC
definition:
A protein complex that can methylate lysine-4 of histone H3. MLL1/MLL is the catalytic methyltransferase subunit, and the complex also contains the core components ASH2L, HCFC1/HCF1 WDR5 and RBBP5.


go_id: GO:0071340
term: skeletal muscle acetylcholine-gated channel clustering
ontology: BP
definition:
The accumulation of acetylcholine-gated cation channels in a narrow, central region of muscle fibers, in apposition to nerve terminals.


go_id: GO:0071341
term: medial cortical node
ontology: CC
definition:
A component of the cell division site that contains the mid1, cdr2, wee1, klp8, and blt1 proteins, and is involved in contractile ring localization. Medial cortical node complexes appear as cortical dots in the middle of the cell during interphase, and function to recruit other ring components in early mitosis.


go_id: GO:0071342
term: regulation of establishment of actomyosin contractile ring localization
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the process in which a contractile ring is assembled in a specific location that contributes to cytokinesis during cell cycle.


go_id: GO:0071345
term: cellular response to cytokine stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.


go_id: GO:0071346
term: cellular response to interferon-gamma
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon gamma is the only member of the type II interferon found so far.


go_id: GO:0071347
term: cellular response to interleukin-1
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus.


go_id: GO:0071348
term: cellular response to interleukin-11
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-11 stimulus.


go_id: GO:0071349
term: cellular response to interleukin-12
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-12 stimulus.


go_id: GO:0071350
term: cellular response to interleukin-15
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-15 stimulus.


go_id: GO:0071351
term: cellular response to interleukin-18
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-18 stimulus.


go_id: GO:0071352
term: cellular response to interleukin-2
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-2 stimulus.


go_id: GO:0071353
term: cellular response to interleukin-4
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-4 stimulus.


go_id: GO:0071354
term: cellular response to interleukin-6
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-6 stimulus.


go_id: GO:0071355
term: cellular response to interleukin-9
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-9 stimulus.


go_id: GO:0071356
term: cellular response to tumor necrosis factor
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus.


go_id: GO:0071357
term: cellular response to type I interferon
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type I interferon stimulus. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.


go_id: GO:0071358
term: cellular response to type III interferon
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type III interferon stimulus. Interferon lambda is the only member of the type III interferon found so far.


go_id: GO:0071359
term: cellular response to dsRNA
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded RNA stimulus.


go_id: GO:0071360
term: cellular response to exogenous dsRNA
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an exogenous double-stranded RNA stimulus.


go_id: GO:0071361
term: cellular response to ethanol
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.


go_id: GO:0071362
term: cellular response to ether
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ether stimulus.


go_id: GO:0071363
term: cellular response to growth factor stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.


go_id: GO:0071364
term: cellular response to epidermal growth factor stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus.


go_id: GO:0071365
term: cellular response to auxin stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus.


go_id: GO:0071366
term: cellular response to indolebutyric acid stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indolebutyric acid stimulus.


go_id: GO:0071367
term: cellular response to brassinosteroid stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brassinosteroid stimulus.


go_id: GO:0071368
term: cellular response to cytokinin stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokinin stimulus.


go_id: GO:0071369
term: cellular response to ethylene stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethylene (ethene) stimulus.


go_id: GO:0071370
term: cellular response to gibberellin stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gibberellin stimulus.


go_id: GO:0071371
term: cellular response to gonadotropin stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin stimulus.


go_id: GO:0071372
term: cellular response to follicle-stimulating hormone stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a follicle-stimulating hormone stimulus.


go_id: GO:0071373
term: cellular response to luteinizing hormone stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a luteinizing hormone stimulus.


go_id: GO:0071374
term: cellular response to parathyroid hormone stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a parathyroid hormone stimulus.


go_id: GO:0071375
term: cellular response to peptide hormone stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals.


go_id: GO:0071376
term: cellular response to corticotropin-releasing hormone stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticotropin-releasing hormone stimulus. Corticotropin-releasing hormone is a peptide hormone involved in the stress response.


go_id: GO:0071377
term: cellular response to glucagon stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus.


go_id: GO:0071378
term: cellular response to growth hormone stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone stimulus. Growth hormone is a peptide hormone that binds to the growth hormone receptor and stimulates growth.


go_id: GO:0071379
term: cellular response to prostaglandin stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin stimulus.


go_id: GO:0071380
term: cellular response to prostaglandin E stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin E stimulus.


go_id: GO:0071381
term: cellular response to prostaglandin F stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin F stimulus.


go_id: GO:0071382
term: cellular response to prostaglandin I stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin I stimulus.


go_id: GO:0071383
term: cellular response to steroid hormone stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus.


go_id: GO:0071384
term: cellular response to corticosteroid stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids.


go_id: GO:0071385
term: cellular response to glucocorticoid stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.


go_id: GO:0071386
term: cellular response to corticosterone stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosterone stimulus. Corticosterone is a 21 carbon steroid hormone of the corticosteroid type, produced in the cortex of the adrenal glands. In many species, corticosterone is the principal glucocorticoid, involved in regulation of fuel metabolism, immune reactions, and stress responses.


go_id: GO:0071387
term: cellular response to cortisol stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisol stimulus. Cortisol is the major natural glucocorticoid synthesized in the zona fasciculata of the adrenal cortex; it affects the metabolism of glucose, protein, and fats and has appreciable mineralocorticoid activity. It also regulates the immune system and affects many other functions.


go_id: GO:0071388
term: cellular response to cortisone stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisone stimulus. Cortisone is a natural glucocorticoid steroid hormone that is metabolically convertible to cortisol. Cortisone is synthesized from cholesterol in the cortex of the adrenal gland under the stimulation of adrenocorticotropin hormone (ACTH). The main physiological effect of cortisone is on carbohydrate metabolism; it can stimulate increased glucose release from the liver, increased liver glycogen synthesis, and decreased utilization of glucose by the tissues.


go_id: GO:0071389
term: cellular response to mineralocorticoid stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mineralocorticoid stimulus. Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. Mineralocorticoids act primarily on water and electrolyte balance.


go_id: GO:0071390
term: cellular response to ecdysone
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ecdysone stimulus.


go_id: GO:0071391
term: cellular response to estrogen stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics.


go_id: GO:0071392
term: cellular response to estradiol stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.


go_id: GO:0071393
term: cellular response to progesterone stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.


go_id: GO:0071394
term: cellular response to testosterone stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus.


go_id: GO:0071395
term: cellular response to jasmonic acid stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus.


go_id: GO:0071396
term: cellular response to lipid
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus.


go_id: GO:0071397
term: cellular response to cholesterol
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholesterol stimulus.


go_id: GO:0071398
term: cellular response to fatty acid
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus.


go_id: GO:0071399
term: cellular response to linoleic acid
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a linoleic acid stimulus.


go_id: GO:0071400
term: cellular response to oleic acid
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oleic acid stimulus.


go_id: GO:0071401
term: cellular response to triglyceride
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triglyceride stimulus.


go_id: GO:0071402
term: cellular response to lipoprotein particle stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoprotein particle stimulus.


go_id: GO:0071403
term: cellular response to high density lipoprotein particle stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high density lipoprotein particle stimulus.


go_id: GO:0071404
term: cellular response to low-density lipoprotein particle stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low-density lipoprotein particle stimulus.


go_id: GO:0071405
term: cellular response to methanol
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methanol stimulus.


go_id: GO:0071406
term: cellular response to methylmercury
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylmercury stimulus.


go_id: GO:0071407
term: cellular response to organic cyclic compound
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.


go_id: GO:0071408
term: cellular response to cycloalkane
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloalkane stimulus. A cycloalkane is a cyclic saturated hydrocarbon having the general formula CnH2n.


go_id: GO:0071409
term: cellular response to cycloheximide
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloheximide stimulus. Cycloheximide (actidione) is an antibiotic produced by some Streptomyces species which interferes with protein synthesis in eukaryotes.


go_id: GO:0071410
term: cellular response to cyclopentenone
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclopentenone stimulus. Cyclopentenones are oxylipins derived from polyunsaturated fatty acids. They are structurally similar to jasmonic acid, but contain a reactive unsaturated carbonyl structure in the cyclo-ring. Cyclopentenones include phytoprostanes and 12-oxo-phytodienoic acid.


go_id: GO:0071411
term: cellular response to fluoxetine
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoxetine stimulus. Fluoxetine increases the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, increasing the level of serotonin available to bind to the postsynaptic receptor.


go_id: GO:0071412
term: cellular response to genistein
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a genistein stimulus.


go_id: GO:0071413
term: cellular response to hydroxyisoflavone
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyisoflavone stimulus.


go_id: GO:0071414
term: cellular response to methotrexate
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methotrexate stimulus. Methotrexate is 4-amino-10-methylformic acid, a folic acid analogue that is a potent competitive inhibitor of dihydrofolate reductase.


go_id: GO:0071415
term: cellular response to purine-containing compound
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purine-containing compound stimulus.


go_id: GO:0071416
term: cellular response to tropane
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tropane stimulus. Tropane is a nitrogenous bicyclic organic compound mainly known for a group of alkaloids derived from it (called tropane alkaloids), which include, among others, atropine and cocaine.


go_id: GO:0071417
term: cellular response to organonitrogen compound
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond.


go_id: GO:0071418
term: cellular response to amine stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups.


go_id: GO:0071419
term: cellular response to amphetamine
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amphetamine stimulus. Amphetamines consist of a group of compounds related to alpha-methylphenethylamine.


go_id: GO:0071420
term: cellular response to histamine
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.


go_id: GO:0071421
term: manganese ion transmembrane transport
ontology: BP
definition:
A process in which a manganese ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.


go_id: GO:0071424
term: rRNA (cytosine-N4-)-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: a cytidine in rRNA + S-adenosyl-L-methionine = an N(4)-methylcytidine in rRNA + H+ + S-adenosyl-L-homocysteine.


go_id: GO:0071425
term: hematopoietic stem cell proliferation
ontology: BP
definition:
The expansion of a hematopoietic stem cell population by cell division. A hematopoietic stem cell is a stem cell from which all cells of the lymphoid and myeloid lineages develop.


go_id: GO:0071432
ontology: BP
term:
peptide mating pheromone maturation involved in positive regulation of conjugation with cellular fusion

definition:
The formation of a mature peptide mating pheromone by proteolysis and/or modification of a peptide precursor, occurring in the context of conjugation with cellular fusion.


go_id: GO:0071433
term: cell wall repair
ontology: BP
definition:
A process of cell wall organization that results in the restoration of the cell wall following damage.


go_id: GO:0071439
term: clathrin complex
ontology: CC
definition:
A protein complex that consists of three clathrin heavy chains and three clathrin light chains, organized into a symmetrical three-legged structure called a triskelion. In clathrin-coated vesicles clathrin is the main component of the coat and forms a polymeric mechanical scaffold on the vesicle surface.


go_id: GO:0071440
term: regulation of histone H3-K14 acetylation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the addition of an acetyl group to histone H3 at position 14 of the histone.


go_id: GO:0071441
term: negative regulation of histone H3-K14 acetylation
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of an acetyl group to histone H3 at position 14 of the histone.


go_id: GO:0071442
term: positive regulation of histone H3-K14 acetylation
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the addition of an acetyl group to histone H3 at position 14 of the histone.


go_id: GO:0071444
term: cellular response to pheromone
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus.


go_id: GO:0071446
term: cellular response to salicylic acid stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salicylic acid stimulus.


go_id: GO:0071447
term: cellular response to hydroperoxide
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroperoxide stimulus. Hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH.


go_id: GO:0071448
term: cellular response to alkyl hydroperoxide
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkyl hydroperoxide stimulus. Alkyl hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH, where the substituent is an alkyl group.


go_id: GO:0071449
term: cellular response to lipid hydroperoxide
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid hydroperoxide stimulus. Lipid hydroperoxide is the highly reactive primary oxygenated products of polyunsaturated fatty acids.


go_id: GO:0071450
term: cellular response to oxygen radical
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen radical stimulus. An oxygen radical is any oxygen species that carries a free electron; examples include hydroxyl radicals and the superoxide anion.


go_id: GO:0071451
term: cellular response to superoxide
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion.


go_id: GO:0071452
term: cellular response to singlet oxygen
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a singlet oxygen stimulus. Singlet oxygen is a dioxygen (O2) molecule in which two 2p electrons have similar spin. Singlet oxygen is more highly reactive than the form in which these electrons are of opposite spin, and it is produced in mutant chloroplasts lacking carotenoids and by leukocytes during metabolic burst.


go_id: GO:0071453
term: cellular response to oxygen levels
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen.


go_id: GO:0071454
term: cellular response to anoxia
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating a decline in oxygen levels to trace amounts, <0.1%.


go_id: GO:0071455
term: cellular response to hyperoxia
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating increased oxygen tension.


go_id: GO:0071456
term: cellular response to hypoxia
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.


go_id: GO:0071457
term: cellular response to ozone
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ozone stimulus.


go_id: GO:0071458
term: integral component of cytoplasmic side of endoplasmic reticulum membrane
ontology: CC
definition:
The component of the endoplasmic reticulum membrane consisting of the gene products that penetrate only the cytoplasmic side of the membrane.


go_id: GO:0071459
term: protein localization to chromosome, centromeric region
ontology: BP
definition:
Any process in which a protein is transported to, or maintained at, the centromeric region of a chromosome.


go_id: GO:0071460
term: cellular response to cell-matrix adhesion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cell-matrix adhesion.


go_id: GO:0071461
term: cellular response to redox state
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating redox state. Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important.


go_id: GO:0071462
term: cellular response to water stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water.


go_id: GO:0071463
term: cellular response to humidity
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a humidity stimulus, moisture in the atmosphere.


go_id: GO:0071464
term: cellular response to hydrostatic pressure
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrostatic pressure stimulus. Hydrostatic pressure is the force acting on an object in a system where the fluid is at rest (as opposed to moving). The weight of the fluid above the object creates pressure on it.


go_id: GO:0071465
term: cellular response to desiccation
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desiccation stimulus, extreme dryness resulting from the prolonged deprivation of water.


go_id: GO:0071466
term: cellular response to xenobiotic stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a xenobiotic, a compound foreign to the organism exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.


go_id: GO:0071467
term: cellular response to pH
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.


go_id: GO:0071468
term: cellular response to acidic pH
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution.


go_id: GO:0071469
term: cellular response to alkaline pH
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH > 7. pH is a measure of the acidity or basicity of an aqueous solution.


go_id: GO:0071470
term: cellular response to osmotic stress
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.


go_id: GO:0071471
term: cellular response to non-ionic osmotic stress
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of non-ionic solutes (e.g. mannitol, sorbitol) in the environment.


go_id: GO:0071472
term: cellular response to salt stress
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.


go_id: GO:0071473
term: cellular response to cation stress
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cation stress, an increase or decrease in the concentration of positively charged ions in the environment.


go_id: GO:0071474
term: cellular hyperosmotic response
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell.


go_id: GO:0071475
term: cellular hyperosmotic salinity response
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.


go_id: GO:0071476
term: cellular hypotonic response
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hypotonic environment, i.e. an environment with a lower concentration of solutes than the organism or cell.


go_id: GO:0071477
term: cellular hypotonic salinity response
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.


go_id: GO:0071478
term: cellular response to radiation
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation.


go_id: GO:0071479
term: cellular response to ionizing radiation
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays.


go_id: GO:0071480
term: cellular response to gamma radiation
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum.


go_id: GO:0071481
term: cellular response to X-ray
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz).


go_id: GO:0071482
term: cellular response to light stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.


go_id: GO:0071483
term: cellular response to blue light
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a blue light stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm.


go_id: GO:0071484
term: cellular response to light intensity
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light intensity stimulus.


go_id: GO:0071485
term: cellular response to absence of light
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an absence of light stimuli.


go_id: GO:0071486
term: cellular response to high light intensity
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high light intensity stimulus.


go_id: GO:0071487
term: cellular response to low light intensity stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low light intensity stimulus. Low light intensity is defined as a level of electromagnetic radiation at or below 0.1 micromols/m2.


go_id: GO:0071488
term: cellular response to very low light intensity stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very low light intensity stimulus. A very low light intensity stimulus is defined as a level of electromagnetic radiation below 0.001 mmol/m2/sec.


go_id: GO:0071489
term: cellular response to red or far red light
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red or far red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.


go_id: GO:0071490
term: cellular response to far red light
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of far red light stimulus. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.


go_id: GO:0071491
term: cellular response to red light
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.


go_id: GO:0071492
term: cellular response to UV-A
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-A radiation stimulus. UV-A radiation (UV-A light) spans the wavelengths 315 to 400 nm.


go_id: GO:0071493
term: cellular response to UV-B
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm.


go_id: GO:0071494
term: cellular response to UV-C
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-C radiation stimulus. UV-C radiation (UV-C light) spans the wavelengths 100 to 280 nm.


go_id: GO:0071495
term: cellular response to endogenous stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism.


go_id: GO:0071496
term: cellular response to external stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus.


go_id: GO:0071497
term: cellular response to freezing
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a freezing stimulus, temperatures below 0 degrees Celsius.


go_id: GO:0071498
term: cellular response to fluid shear stress
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluid shear stress stimulus. Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface.


go_id: GO:0071499
term: cellular response to laminar fluid shear stress
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a laminar fluid shear stress stimulus. Laminar fluid flow is the force acting on an object in a system where the fluid is moving across a solid surface in parallel layers.


go_id: GO:0071500
term: cellular response to nitrosative stress
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions.


go_id: GO:0071501
term: cellular response to sterol depletion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating deprivation of sterols. Sterols are a group of steroids characterized by the presence of one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.


go_id: GO:0071502
term: cellular response to temperature stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus.


go_id: GO:0071503
term: response to heparin
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heparin stimulus.


go_id: GO:0071504
term: cellular response to heparin
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heparin stimulus.


go_id: GO:0071505
term: response to mycophenolic acid
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycophenolic acid stimulus.


go_id: GO:0071506
term: cellular response to mycophenolic acid
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycophenolic acid stimulus.


go_id: GO:0071513
term: phosphopantothenoylcysteine decarboxylase complex
ontology: CC
definition:
A protein complex that catalyzes decarboxylation of 4'-phosphopantothenoylcysteine to yield 4'-phosphopantetheine; this is the third step in the biosynthesis of Coenzyme A. The complex is homotrimeric in many eukaryotes, but is a heterotrimer in Saccharomyces.


go_id: GO:0071514
term: genomic imprinting
ontology: BP
definition:
The establishment of epigenetic modifications (imprints) during gametogenesis, leading to an asymmetry in the heterochromatin between the maternal and paternal alleles, and differential expression of the corresponding alleles. This asymmetry results from the different epigenetic pathways acting in maternal and paternal gametes.


go_id: GO:0071515
term: mating-type locus imprinting
ontology: BP
definition:
A genomic imprinting process in which a stable single-strand DNA lesion triggers programmed gene conversion at the mating-type locus, thereby restricting mating-type interconversion to one of the two sister chromatids during DNA replication.


go_id: GO:0071518
term: autoinducer-2 kinase activity
ontology: MF
definition:
Catalysis of the reaction: 4,5-dihydroxy-pentane-2,3-dione + ATP = 5-phospho-4-hydroxy-pentane-2,3-dione (P-DPD) + ADP.


go_id: GO:0071519
term: actomyosin contractile ring actin filament bundle assembly
ontology: BP
definition:
A process of actin filament bundle formation that occurs in the context of assembling an actomyosin contractile ring during cytokinesis.


go_id: GO:0071520
term: actomyosin contractile ring assembly actin filament bundle convergence
ontology: BP
definition:
A process of actin filament bundle distribution that occurs in the context of assembling an actomyosin contractile ring during cytokinesis, and that results in the compaction of actin filaments into a tight ring.


go_id: GO:0071521
term: Cdc42 GTPase complex
ontology: CC
definition:
A protein complex formed by the association of the small GTPase Cdc42 with additional proteins. In Schizosaccharomyces the complex contains the Cdc42, Ras1, Scd1, Scd2, andShk1 proteins, and functions in the Ras1-Scd GTPase signalling pathway.


go_id: GO:0071524
term: pyrrolysine biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of pyrrolysine, N6-{[(2R,3R)-3-methyl-3,4-dihydro-2H-pyrrol-2-yl]carbonyl}-L-lysine.


go_id: GO:0071525
term: pyrrolysine metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving pyrrolysine, N6-{[(2R,3R)-3-methyl-3,4-dihydro-2H-pyrrol-2-yl]carbonyl}-L-lysine.


go_id: GO:0071526
term: semaphorin-plexin signaling pathway
ontology: BP
definition:
The series of molecular signals generated as a consequence of a semaphorin receptor (composed of a plexin and a neurophilin) binding to a semaphorin ligand.


go_id: GO:0071527
term: semaphorin-plexin signaling pathway involved in outflow tract morphogenesis
ontology: BP
definition:
The series of molecular signals generated as a consequence of a semaphorin receptor (composed of a plexin and a neurophilin) binding to a semaphorin ligand that contributes to outflow tract morphogenesis.


go_id: GO:0071528
term: tRNA re-export from nucleus
ontology: BP
definition:
The directed movement from the nucleus to the cytoplasm of a tRNA that was previously exported to the cytoplasm and then imported back into the nucleus. The processes of primary tRNA export and secondary export (re-export) can be distinguished because in organisms in which tRNA splicing occurs in the cytoplasm, the export of a mature tRNA must occur by re-export.


go_id: GO:0071529
term: cementum mineralization
ontology: BP
definition:
The process in which calcium salts, mainly carbonated hydroxyapatite, are deposited into the initial acellular cementum.


go_id: GO:0071532
term: ankyrin repeat binding
ontology: MF
definition:
Binding to an ankyrin repeat of a protein. Ankyrin repeats are tandemly repeated modules of about 33 amino acids; each repeat folds into a helix-loop-helix structure with a beta-hairpin/loop region projecting out from the helices at a 90-degree angle, and repeats stack to form an L-shaped structure.


