# go_term

go_id: GO:0033211
term: adiponectin-activated signaling pathway
ontology: BP
definition:
The series of molecular signals initiated by adiponectin binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


go_id: GO:0033212
term: iron import into cell
ontology: BP
definition:
The directed movement of iron ions from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.


go_id: GO:0033214
term: siderophore-dependent iron import into cell
ontology: BP
definition:
A process in which iron (Fe3+) is solubilized by ferric iron-specific chelators, known as siderophores, excreted by a cell; the iron-siderophore complex is then transported into the cell by specific cell surface receptors.


go_id: GO:0033215
term: reductive iron assimilation
ontology: BP
definition:
A process in which iron is solubilized by reduction from Fe3+ to Fe2+ via a cell surface reductase and subsequent transport of the iron across the membrane by iron uptake proteins.


go_id: GO:0033217
term: regulation of transcription from RNA polymerase II promoter in response to iron ion starvation
ontology: BP
definition:
Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of iron ions.


go_id: GO:0033218
term: amide binding
ontology: MF
definition:
Binding to an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group.


go_id: GO:0033223
term: 2-aminoethylphosphonate transport
ontology: BP
definition:
The directed movement of 2-aminoethylphosphonate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0033225
term: ATPase-coupled 2-aminoethylphosphonate transporter activity
ontology: MF
definition:
Enables the directed movement of 2-aminoethylphosphonate from one side of a membrane to the other by catalysis of the reaction: ATP + H2O + 2-aminoethylphosphonate(out) = ADP + phosphate + 2-aminoethylphosphonate(in).


go_id: GO:0033227
term: dsRNA transport
ontology: BP
definition:
The directed movement of dsRNA, double-stranded ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0033228
term: cysteine export across plasma membrane
ontology: BP
definition:
The directed movement of cysteine from inside of a cell, across the plasma membrane and into the extracellular region.


go_id: GO:0033230
term: ABC-type cysteine transporter activity
ontology: MF
definition:
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + cysteine(out/in) = ADP + phosphate + cysteine(in/out).


go_id: GO:0033232
term: ABC-type D-methionine transporter activity
ontology: MF
definition:
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-methionine(out/in) = ADP + phosphate + D-methionine(in/out).


go_id: GO:0033233
term: regulation of protein sumoylation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the addition of SUMO groups to a protein.


go_id: GO:0033234
term: negative regulation of protein sumoylation
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of SUMO groups to a protein.


go_id: GO:0033235
term: positive regulation of protein sumoylation
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the addition of SUMO groups to a protein.


go_id: GO:0033238
term: regulation of cellular amine metabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform amines.


go_id: GO:0033239
term: negative regulation of cellular amine metabolic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amines.


go_id: GO:0033240
term: positive regulation of cellular amine metabolic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amines.


go_id: GO:0033241
term: regulation of cellular amine catabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines.


go_id: GO:0033242
term: negative regulation of cellular amine catabolic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines.


go_id: GO:0033243
term: positive regulation of cellular amine catabolic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines.


go_id: GO:0033244
term: regulation of penicillin metabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system.


go_id: GO:0033245
term: negative regulation of penicillin metabolic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system.


go_id: GO:0033246
term: positive regulation of penicillin metabolic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system.


go_id: GO:0033247
term: regulation of penicillin catabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system.


go_id: GO:0033248
term: negative regulation of penicillin catabolic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system.


go_id: GO:0033249
term: positive regulation of penicillin catabolic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system.


go_id: GO:0033250
term: penicillinase activity
ontology: MF
definition:
Catalysis of the reaction: a penicillin + H2O = a substituted beta-amino acid derivative of the penicillin.


go_id: GO:0033251
term: cephalosporinase activity
ontology: MF
definition:
Catalysis of the reaction: a cephalosporin + H2O = a substituted beta-amino acid derivative of the cephalosporin.


go_id: GO:0033252
term: regulation of beta-lactamase activity
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of beta-lactamase activity, the hydrolysis of a beta-lactam to yield a substituted beta-amino acid.


go_id: GO:0033253
term: regulation of penicillinase activity
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of nuclease activity, the hydrolysis of a penicillin to yield a substituted beta-amino acid derivative.


go_id: GO:0033254
term: vacuolar transporter chaperone complex
ontology: CC
definition:
A protein complex that contains four related proteins that have been implicated in several membrane-related processes, such as sorting of H+-translocating ATPases, endocytosis, ER-Golgi trafficking, vacuole fusion, vacuolar polyphosphate homeostasis and the microautophagic scission of vesicles into the vacuolar lumen. The complex is enriched at the vacuolar membrane, but also found in other cellular compartments, including the ER and the cell periphery. In Saccharomyces, the subunits are Vtc1p, Vtc2p, Vtc3p and Vtc4p.


go_id: GO:0033255
term: SAS acetyltransferase complex
ontology: CC
definition:
A protein complex that possesses histone acetyltransferase activity and links histone acetylation to the assembly of transcriptionally silent chromatin. In vitro, the complex acetylates lysine 16 of histone H4 and lysine 14 of histone H3, although the latter may not be relevant in vivo. The complex contains a catalytic subunit and at least two other subunits; in Saccharomyces, the catalytic subunit is Sas2p and additional subunits are Sas4p and Sas5p.


go_id: GO:0033256
term: I-kappaB/NF-kappaB complex
ontology: CC
definition:
A protein complex containing an inhibitory-kappaB (I-kappaB/IKB) protein and one or more copies of an NF-kappaB protein. In the resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering NF-kappaB in the cytoplasm.


go_id: GO:0033257
term: Bcl3/NF-kappaB2 complex
ontology: CC
definition:
A protein complex containing one Bcl protein and one or more copies of NF-kappaB2; formation of complexes of different stoichiometry depends on the Bcl3:NF-kappaB2 ratio, and allow Bcl3 to exert different regulatory effects on NF-kappaB2-dependent transcription.


go_id: GO:0033260
term: nuclear DNA replication
ontology: BP
definition:
The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle.


go_id: GO:0033262
term: regulation of nuclear cell cycle DNA replication
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle.


go_id: GO:0033263
term: CORVET complex
ontology: CC
definition:
A multimeric protein complex that acts as an endosomal tethering complex (CORVET = class C core vacuole/endosome tethering) by cooperating with Rab GTPases to capture endosomal vesicles and trap them prior to the action of SNAREs; the complex is involved in endo-lysosomal biogenesis and required for transport between endosome and vacuole. The Saccharomyces cerevisiae complex contains Vps8p, Vps3p, Pep5p, Vps16p, Pep3p, and Vps33p.


go_id: GO:0033266
term: ABC-type choline transporter activity
ontology: MF
definition:
Catalysis of the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of choline across a membrane.


go_id: GO:0033268
term: node of Ranvier
ontology: CC
definition:
An axon part that is a gap in the myelin where voltage-gated sodium channels cluster and saltatory conduction is executed.


go_id: GO:0033270
term: paranode region of axon
ontology: CC
definition:
An axon part that is located adjacent to the nodes of Ranvier and surrounded by lateral loop portions of myelin sheath.


go_id: GO:0033271
term: myo-inositol phosphate transport
ontology: BP
definition:
The directed movement of any phosphorylated myo-inositol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0033272
term: myo-inositol hexakisphosphate transport
ontology: BP
definition:
The directed movement of myo-inositol hexakisphosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0033273
term: response to vitamin
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin stimulus.


go_id: GO:0033274
term: response to vitamin B2
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B2 stimulus.


go_id: GO:0033276
term: transcription factor TFTC complex
ontology: CC
definition:
A protein complex that does not contain either a TATA-binding protein (TBP) or a TBP-like factor, but is composed of several TAFIIs and other proteins, including a histone acetyltransferase. This complex is able to nucleate transcription initiation by RNA polymerase II, can mediate transcriptional activation, and has histone acetyltransferase activity.


go_id: GO:0033277
term: abortive mitotic cell cycle
ontology: BP
definition:
A cell cycle in which mitosis is begun and progresses normally through the end of anaphase, but not completed, resulting in a cell with increased ploidy.


go_id: GO:0033278
term: cell proliferation in midbrain
ontology: BP
definition:
The multiplication or reproduction of cells, resulting in the expansion of a cell population in the midbrain.


go_id: GO:0033280
term: response to vitamin D
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin D stimulus.


go_id: GO:0033281
term: TAT protein transport complex
ontology: CC
definition:
A complex of three proteins integral to the cytoplasmic membrane of bacteria and membranes of organelles derived from bacteria (chloroplasts and mitochondria) involved in membrane transport of folded proteins.


go_id: GO:0033282
term: protein C inhibitor-acrosin complex
ontology: CC
definition:
A heterodimeric protein complex of protein C inhibitor (SERPINA5) and acrosin; formation of the complex inhibits the protease activity of acrosin.


go_id: GO:0033283
term: ATPase-coupled organic acid transmembrane transporter activity
ontology: MF
definition:
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + organic acid(out/in) = ADP + phosphate + organic acid(in/out).


go_id: GO:0033284
term: ATPase-coupled carboxylic acid transmembrane transporter activity
ontology: MF
definition:
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + carboxylic acid(out/in) = ADP + phosphate + carboxylic acid(in/out).


go_id: GO:0033285
term: ATPase-coupled monocarboxylic acid transmembrane transporter activity
ontology: MF
definition:
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + monocarboxylic acid(out/in) = ADP + phosphate + monocarboxylic acid(in/out).


go_id: GO:0033286
term: ATPase-coupled ectoine transmembrane transporter activity
ontology: MF
definition:
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + ectoine(out/in) = ADP + phosphate + ectoine(in/out).


go_id: GO:0033288
term: ATPase-coupled hydroxyectoine transmembrane transporter activity
ontology: MF
definition:
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + hydroxyectoine(out/in) = ADP + phosphate + hydroxyectoine(in/out).


go_id: GO:0033290
term: eukaryotic 48S preinitiation complex
ontology: CC
definition:
A protein complex composed of the small ribosomal subunit, eIF3, eIF1A, methionyl-initiatior methionine and a capped mRNA. The complex is initially positioned at the 5'-end of the capped mRNA.


go_id: GO:0033291
term: eukaryotic 80S initiation complex
ontology: CC
definition:
A protein complex composed of the large and small ribosomal subunits, methionyl-initiatior tRNA, and the capped mRNA. The initiator tRNA is positioned at the ribosomal P site at the AUG codon corresponding to the beginning of the coding region.


go_id: GO:0033292
term: T-tubule organization
ontology: BP
definition:
A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of the T-tubule. A T-tubule is an invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril.


go_id: GO:0033293
term: monocarboxylic acid binding
ontology: MF
definition:
Binding to a monocarboxylic acid, any organic acid containing one carboxyl (COOH) group or anion (COO-).


go_id: GO:0033298
term: contractile vacuole organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a contractile vacuole. A specialized vacuole that fills with water from the cytoplasm and then discharges this externally by the opening of contractile vacuole pores.


go_id: GO:0033300
term: dehydroascorbic acid transmembrane transporter activity
ontology: MF
definition:
Enables the transfer of dehydroascorbate, 5-(1,2-dihydroxyethyl)furan-2,3,4(5H)-trione, from one side of a membrane to the other.


go_id: GO:0033301
term: cell cycle comprising mitosis without cytokinesis
ontology: BP
definition:
A mitotic cell cycle in which mitosis is completed but cytokinesis does not occur, resulting in a cell containing multiple nuclei each with a chromosomal complement of the original ploidy (usually 2N).


go_id: GO:0033303
term: quercetin O-glucoside biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways leading to the formation of O-glucosylated derivatives of quercetin.


go_id: GO:0033306
term: phytol metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving phytol, (2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol.


go_id: GO:0033307
term: phytol salvage
ontology: BP
definition:
A process that generates phytol, (2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol, from derivatives of it without de novo synthesis.


go_id: GO:0033308
term: hydroxyectoine transport
ontology: BP
definition:
The directed movement of hydroxyectoine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0033309
term: SBF transcription complex
ontology: CC
definition:
A protein complex that binds to the Swi4/6 cell cycle box (SCB) promoter element, consensus sequence CRCGAAA, and activates transcription during the G1/S transition of the cell cycle. In Saccharomyces, the complex contains a heterodimer of the DNA binding protein Swi4p and the activator Swi6p, and is associated with additional proteins known as Whi5p and Msa1p.


go_id: GO:0033311
term: chlorophyll a biosynthetic process via phytyl diphosphate
ontology: BP
definition:
The chemical reactions and pathways leading to the formation of chlorophyll a, via the intermediate phytyl diphosphate.


go_id: GO:0033312
term: chlorophyll a biosynthetic process via geranylgeranyl-chlorophyll a
ontology: BP
definition:
The chemical reactions and pathways leading to the formation of chlorophyll a, via the intermediate geranylgeranyl-chlorophyll a.


go_id: GO:0033313
term: meiotic cell cycle checkpoint signaling
ontology: BP
definition:
A signaling process that contributes to a meiotic cell cycle checkpoint that ensures accurate chromosome replication and segregation by preventing progression through a meiotic cell cycle until conditions are suitable for the cell to proceed to the next stage.


go_id: GO:0033315
term: meiotic G2/MI DNA replication checkpoint signaling
ontology: BP
definition:
A signal transduction process that controls the G2/M1 transition of the meiotic cell cycle and prevents the initiation of nuclear division until DNA replication is complete.


go_id: GO:0033316
term: meiotic spindle assembly checkpoint signaling
ontology: BP
definition:
A signal transduction process that contributes to a meiotic spindle assembly checkpoint, that delays the metaphase/anaphase transition of a meiotic cell cycle until the spindle is correctly assembled and chromosomes are attached to the spindle.


go_id: GO:0033319
term: UDP-D-xylose metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving UDP-D-xylose, uridinediphosphoxylose, a substance composed of xylose in glycosidic linkage with uridine diphosphate.


go_id: GO:0033320
term: UDP-D-xylose biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of UDP-D-xylose, uridinediphosphoxylose, a substance composed of xylose in glycosidic linkage with uridine diphosphate.


go_id: GO:0033321
term: homomethionine metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving homomethionine, a non-protein amino acid synthesized from methionine via chain elongation.


go_id: GO:0033322
term: homomethionine biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of homomethionine, a non-protein amino acid synthesized from methionine via chain elongation.


go_id: GO:0033323
term: choline biosynthetic process via CDP-choline
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), via the intermediate CDP-choline.


go_id: GO:0033324
term: choline biosynthetic process via N-monomethylethanolamine
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), via the intermediate N-monomethylethanolamine.


go_id: GO:0033325
term: choline biosynthetic process via phosphoryl-ethanolamine
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), via the intermediate phosphoryl-ethanolamine.


go_id: GO:0033326
term: cerebrospinal fluid secretion
ontology: BP
definition:
The regulated release of cerebrospinal fluid (CSF) from the choroid plexus of the lateral, third and fourth ventricles. The cerebrospinal fluid is a clear liquid that located within the ventricles, spinal canal, and subarachnoid spaces.


go_id: GO:0033327
term: Leydig cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Leydig cell. A Leydig cell is a testosterone-secreting cell in the interstitial area, between the seminiferous tubules, in the testis.


go_id: GO:0033328
term: peroxisome membrane targeting sequence binding
ontology: MF
definition:
Binding to a peroxisomal membrane targeting sequence, any of several sequences of amino acids within a protein that can act as a signal for the localization of the protein into the peroxisome membrane.


go_id: GO:0033330
term: kaempferol O-glucoside biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways leading to the formation of O-glucosylated derivatives of kaempferol.


go_id: GO:0033331
term: ent-kaurene metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving ent-kaur-16-ene. Ent-kaurene is a tetracyclic diterpenoid that is a precursor of several plant isoprenoids, including gibberellins.


go_id: GO:0033332
term: ent-kaurene biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of ent-kaurene. Ent-kaurene is a tetracyclic diterpenoid that is a precursor of several plant isoprenoids, including gibberellins.


go_id: GO:0033333
term: fin development
ontology: BP
definition:
The process whose specific outcome is the progression of a fin over time, from its formation to the mature structure.


go_id: GO:0033335
term: anal fin development
ontology: BP
definition:
The process whose specific outcome is the progression of the anal fin over time, from its formation to the mature structure.


go_id: GO:0033336
term: caudal fin development
ontology: BP
definition:
The process whose specific outcome is the progression of the caudal fin over time, from its formation to the mature structure.


go_id: GO:0033337
term: dorsal fin development
ontology: BP
definition:
The process whose specific outcome is the progression of the dorsal fin over time, from its formation to the mature structure.


go_id: GO:0033338
term: medial fin development
ontology: BP
definition:
The process whose specific outcome is the progression of a medial fin over time, from its formation to the mature structure.


go_id: GO:0033339
term: pectoral fin development
ontology: BP
definition:
The process whose specific outcome is the progression of the pectoral fin over time, from its formation to the mature structure.


go_id: GO:0033340
term: pelvic fin development
ontology: BP
definition:
The process whose specific outcome is the progression of the pelvic fin over time, from its formation to the mature structure.


go_id: GO:0033345
term: asparagine catabolic process via L-aspartate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate L-aspartate.


go_id: GO:0033346
term: asparagine catabolic process via 2-oxosuccinamate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate 2-oxosuccinamate.


go_id: GO:0033347
term: tetrose metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving a tetrose, any monosaccharide with a chain of four carbon atoms in the molecule.


go_id: GO:0033348
term: tetrose biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a tetrose, any monosaccharide with a chain of four carbon atoms in the molecule.


go_id: GO:0033349
term: apiose metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving apiose, the branched tetrose 3-C-(hydroxymethyl)-D-glycero-tetrose.


go_id: GO:0033350
term: apiose biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of apiose, the branched tetrose 3-C-(hydroxymethyl)-D-glycero-tetrose.


go_id: GO:0033351
term: UDP-D-apiose metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving UDP-D-apiose, uridinediphosphoapiose, a substance composed of apiose in glycosidic linkage with uridine diphosphate.


go_id: GO:0033352
term: UDP-D-apiose biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of UDP-D-apiose, uridinediphosphoapicose, a substance composed of apiose in glycosidic linkage with uridine diphosphate.


go_id: GO:0033353
term: S-adenosylmethionine cycle
ontology: BP
definition:
A cyclic series of interconversions involving S-adenosylmethionine, S-adenosyl-L-homocysteine, L-cysteine, and L-methionine. Couples utilization of the methyl group of SAM with recycling of the homocysteinyl group and regeneration of methionine.


go_id: GO:0033354
term: chlorophyll cycle
ontology: BP
definition:
A cyclic series of interconversions involving chlorophyll a, chlorophyll b and several chlorophyllide intermediates.


go_id: GO:0033355
term: ascorbate glutathione cycle
ontology: BP
definition:
A cyclic series of interconversions involving L-ascorbate and glutathione that scavenges hydrogen peroxide and reduces it to water, with concomitant oxidation of NADPH.


go_id: GO:0033356
term: UDP-L-arabinose metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving UDP-L-arabinose, uridinediphosphoarabinose, a substance composed of arabinose in glycosidic linkage with uridine diphosphate.


go_id: GO:0033358
term: UDP-L-arabinose biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of UDP-L-arabinose, uridinediphosphoarabinose, a substance composed of arabinose in glycosidic linkage with uridine diphosphate.


go_id: GO:0033359
term: lysine biosynthetic process via diaminopimelate and N-succinyl-2-amino-6-ketopimelate
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of lysine, via the intermediates diaminopimelate and N-succinyl-2-amino-6-ketopimelate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in four enzymatic steps.


go_id: GO:0033360
term: lysine biosynthetic process via diaminopimelate and L-2-acetamido-6-oxoheptanedioate
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of lysine, via the intermediates diaminopimelate and L-2-acetamido-6-oxoheptanedioate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in four enzymatic steps.


go_id: GO:0033361
term: lysine biosynthetic process via diaminopimelate, dehydrogenase pathway
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in a single enzymatic step.


go_id: GO:0033362
term: lysine biosynthetic process via diaminopimelate, diaminopimelate-aminotransferase pathway
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in two enzymatic steps.


go_id: GO:0033363
term: secretory granule organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion.


go_id: GO:0033364
term: mast cell secretory granule organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a mast cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion.


go_id: GO:0033366
term: protein localization to secretory granule
ontology: BP
definition:
A process in which a protein is transported to, or maintained in, a location within a secretory granule.


go_id: GO:0033367
term: protein localization to mast cell secretory granule
ontology: BP
definition:
A process in which a protein is transported to, or maintained in, a location within a secretory granule in a mast cell.


go_id: GO:0033368
term: protease localization to mast cell secretory granule
ontology: BP
definition:
Any process in which a protease is transported to, or maintained in, a location within a secretory granule in a mast cell.


go_id: GO:0033370
term: maintenance of protein location in mast cell secretory granule
ontology: BP
definition:
A process in which a protein is maintained in a secretory granule in a mast cell and prevented from moving elsewhere.


go_id: GO:0033371
term: T cell secretory granule organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a T cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion.


go_id: GO:0033373
term: maintenance of protease location in mast cell secretory granule
ontology: BP
definition:
A process in which a protease is maintained in a secretory granule in a mast cell and prevented from moving elsewhere.


go_id: GO:0033374
term: protein localization to T cell secretory granule
ontology: BP
definition:
A process in which a protein is transported to, or maintained in, a location within a secretory granule in a T cell.


go_id: GO:0033375
term: protease localization to T cell secretory granule
ontology: BP
definition:
Any process in which a protease is transported to, or maintained in, a location within a secretory granule in a T cell.


go_id: GO:0033377
term: maintenance of protein location in T cell secretory granule
ontology: BP
definition:
A process in which a protein is maintained in a secretory granule in a T cell and prevented from moving elsewhere.


go_id: GO:0033379
term: maintenance of protease location in T cell secretory granule
ontology: BP
definition:
A process in which a protease is maintained in a secretory granule in a T cell and prevented from moving elsewhere.


go_id: GO:0033380
term: granzyme B localization to T cell secretory granule
ontology: BP
definition:
Any process in which the protease granzyme B is transported to, or maintained in, a location within a secretory granule in a T cell.


go_id: GO:0033381
term: establishment of granzyme B localization to T cell secretory granule
ontology: BP
definition:
The directed movement of the protease granzyme B to a location within a secretory granule in a T cell.


go_id: GO:0033382
term: maintenance of granzyme B location in T cell secretory granule
ontology: BP
definition:
A process in which the protease granyme B is maintained in a secretory granule in a T cell and prevented from moving elsewhere.


go_id: GO:0033383
term: geranyl diphosphate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving geranyl diphosphate, the universal precursor of the monoterpenes.


go_id: GO:0033385
term: geranylgeranyl diphosphate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving geranylgeranyl diphosphate, a polyprenol compound involved in the biosynthesis of a variety of terpenoids including chlorophylls, carotenoids, tocopherols, plastoquinones, and the plant hormones gibberellins.


go_id: GO:0033387
term: putrescine biosynthetic process from ornithine
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane by decarboxylation of ornithine.


go_id: GO:0033388
term: putrescine biosynthetic process from arginine
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine.


go_id: GO:0033389
term: putrescine biosynthetic process from arginine, using agmatinase
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine; in this pathway, arginine is converted to agmatine, and agmatine is converted to putrescine in a single enzymatic step.


go_id: GO:0033390
term: putrescine biosynthetic process from arginine via N-carbamoylputrescine
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine, via the intermediate N-carbamoylputrescine; in this pathway, arginine is converted to agmatine, and agmatine is converted to putrescine in two single enzymatic steps.


go_id: GO:0033391
term: chromatoid body
ontology: CC
definition:
A ribonucleoprotein complex found in the cytoplasm of male germ cells, composed of exceedingly thin filaments that are consolidated into a compact mass or into dense strands of varying thickness that branch to form an irregular network. Contains mRNAs, miRNAs, and protein components involved in miRNA processing (such as Argonaute proteins and the endonuclease Dicer) and in RNA decay (such as the decapping enzyme DCP1a and GW182).


go_id: GO:0033393
term: homogalacturonan catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of homogalacturonan, a pectidic polymer, characterized by a backbone of 1,4-linked alpha-D-GalpA residues that can be methyl-esterified at C-6 and carry acetyl groups on O-2 and O-3.


go_id: GO:0033394
term: beta-alanine biosynthetic process via 1,3 diaminopropane
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of beta-alanine via the intermediate 1,3 diaminopropane.


go_id: GO:0033395
term: beta-alanine biosynthetic process via 3-hydroxypropionate
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of beta-alanine via the intermediate 3-hydroxypropionate.


go_id: GO:0033396
term: beta-alanine biosynthetic process via 3-ureidopropionate
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of beta-alanine via the intermediate 3-ureidopropionate.


go_id: GO:0033398
term: zeatin biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of zeatin, 2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol.


go_id: GO:0033399
term: cis-zeatin metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving cis-zeatin, (2Z)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol.


go_id: GO:0033400
term: trans-zeatin metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving trans-zeatin, (2E)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol.


go_id: GO:0033465
term: cis-zeatin biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of cis-zeatin, (2Z)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol.


go_id: GO:0033466
term: trans-zeatin biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of trans-zeatin, (2E)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol.


go_id: GO:0033467
term: CMP-keto-3-deoxy-D-manno-octulosonic acid metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving CMP-keto-3-deoxy-D-manno-octulosonic acid, a substance composed of the acidic sugar 3-deoxy-D-manno-octulosonic acid in glycosidic linkage with cytidine monophosphate.


go_id: GO:0033468
term: CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of CMP-keto-3-deoxy-D-manno-octulosonic acid, a substance composed of the acidic sugar 3-deoxy-D-manno-octulosonic acid in glycosidic linkage with cytidine monophosphate.


go_id: GO:0033469
term: gibberellin 12 metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving gibberellin 12, (1R,2S,3S,4R,8S,9S,12R)-4,8-dimethyl-13-methylidenetetracyclo[10.2.1.01,9.03,8]pentadecane-2,4-dicarboxylic acid 1meta,4a-dimethyl-8-methylidene-4aalpha,4bbeta-gibbane-1alpha,10beta-dicarboxylic acid.


go_id: GO:0033470
term: gibberellin 12 biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of gibberellin 12, (1R,2S,3S,4R,8S,9S,12R)-4,8-dimethyl-13-methylidenetetracyclo[10.2.1.01,9.03,8]pentadecane-2,4-dicarboxylic acid 1meta,4a-dimethyl-8-methylidene-4aalpha,4bbeta-gibbane-1alpha,10beta-dicarboxylic acid.


go_id: GO:0033471
term: GDP-L-galactose metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving GDP-L-galactose, a substance composed of L-galactose in glycosidic linkage with guanosine diphosphate.


go_id: GO:0033472
term: GDP-L-galactose biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of GDP-L-galactose, a substance composed of L-galactose in glycosidic linkage with guanosine diphosphate.


go_id: GO:0033473
term: indoleacetic acid conjugate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving any indole-3-acetic acid conjugate, a form of indoleacetic acid covalently bound to another molecule.


go_id: GO:0033474
term: indoleacetic acid conjugate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of an indole-3-acetic acid conjugate, a form of indoleacetic acid covalently bound to another molecule.


go_id: GO:0033475
term: indoleacetic acid amide conjugate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of an indole-3-acetic acid amide conjugate, a form of indoleacetic acid covalently bound to an amino acid or polypeptide through an amide bond.


go_id: GO:0033476
term: indoleacetic acid ester conjugate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of an indole-3-acetic acid amide conjugate, a form of indoleacetic acid covalently bound to an a sugar or polyol through an ester bond.


go_id: GO:0033477
term: S-methylmethionine metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving S-methyl-methionine (SMM). SMM can be converted to methionine by donating a methyl group to homocysteine, and concurrent operation of this reaction and that mediated by MMT sets up the SMM cycle.


go_id: GO:0033478
term: UDP-rhamnose metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving UDP-L-rhamnose, a substance composed of rhamnose in glycosidic linkage with uridine diphosphate.


go_id: GO:0033479
term: UDP-D-galacturonate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving UDP-D-galacturonate, a substance composed of galacturonic acid in glycosidic linkage with uridine diphosphate.


go_id: GO:0033480
term: UDP-D-galacturonate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of UDP-D-galacturonate, a substance composed of galacturonic acid in glycosidic linkage with uridine diphosphate.


go_id: GO:0033481
term: galacturonate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of galacturonate, the anion of galacturonic acid.


go_id: GO:0033482
term: D-galacturonate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of D-galacturonate, the D-enantiomer of galacturonate, the anion of galacturonic acid.


go_id: GO:0033483
term: gas homeostasis
ontology: BP
definition:
A homeostatic process involved in the maintenance of an internal steady state of a gas within an organism or cell.


go_id: GO:0033484
term: nitric oxide homeostasis
ontology: BP
definition:
A homeostatic process involved in the maintenance of an internal steady state of nitric oxide within an organism or cell.


go_id: GO:0033485
term: cyanidin 3-O-glucoside biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of cyanidin 3-O-glucoside, a basic anthocyanin responsible for red to magenta coloration of flowers and fruits.


go_id: GO:0033486
term: delphinidin 3-O-glucoside biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of delphinidin 3-O-glucoside, a basic, water-soluble anthocyanin responsible for blue coloration of flowers and fruits.


go_id: GO:0033487
term: pelargonidin 3-O-glucoside biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of pelargonidin 3-O-glucoside, a basic anthocyanin responsible for red to magenta coloration of flowers and fruits.


go_id: GO:0033488
term: cholesterol biosynthetic process via 24,25-dihydrolanosterol
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate 24,25-dihydrolanosterol.


go_id: GO:0033489
term: cholesterol biosynthetic process via desmosterol
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate desmosterol.


go_id: GO:0033490
term: cholesterol biosynthetic process via lathosterol
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate lathosterol.


go_id: GO:0033491
term: coniferin metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving coniferin, 4-(3-hydroxyprop-1-en-1-yl)-2-methoxyphenyl beta-D-glucopyranoside.


go_id: GO:0033494
term: ferulate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving ferulate, (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate.


go_id: GO:0033495
term: ferulate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of ferulate, (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate.


go_id: GO:0033496
term: sinapate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate.


go_id: GO:0033497
term: sinapate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate.


go_id: GO:0033498
term: galactose catabolic process via D-galactonate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of galactose, via the intermediate D-galactonate.


go_id: GO:0033499
term: galactose catabolic process via UDP-galactose
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of galactose, via the intermediate UDP-galactose.


go_id: GO:0033500
term: carbohydrate homeostasis
ontology: BP
definition:
A homeostatic process involved in the maintenance of an internal steady state of a carbohydrate within an organism or cell.


go_id: GO:0033501
term: galactose homeostasis
ontology: BP
definition:
A homeostatic process involved in the maintenance of an internal steady state of galactose within an organism or cell.


go_id: GO:0033502
term: cellular galactose homeostasis
ontology: BP
definition:
A cellular homeostatic process involved in the maintenance of an internal steady state of galactose within a cell or between a cell and its external environment.


go_id: GO:0033503
term: HULC complex
ontology: CC
definition:
A ubiquitin ligase complex that contains two RING finger proteins, which have ubiquitin ligase activity, in addition to a protein with ubiquitin-conjugating enzyme activity; catalyzes the ubiquitination of histone H2B at lysine 119 (or the equivalent residue). In Schizosaccharomyces the subunits are Rhp6, Shf1, Brl2/Rfp1 and Brl1/Rfp2.


go_id: GO:0033506
term: glucosinolate biosynthetic process from homomethionine
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of glucosinolates from other compounds including homomethionine.


go_id: GO:0033507
term: glucosinolate biosynthetic process from phenylalanine
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of glucosinolates from other compounds including phenylalanine.


go_id: GO:0033508
term: glutamate catabolic process to butyrate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including butyrate.


go_id: GO:0033509
term: glutamate catabolic process to propionate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including propionate.


go_id: GO:0033510
term: luteolin metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving luteolin, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one.


go_id: GO:0033511
term: luteolin biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of luteolin, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one.


go_id: GO:0033512
term: L-lysine catabolic process to acetyl-CoA via saccharopine
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA, via the intermediate saccharopine.


go_id: GO:0033513
term: L-lysine catabolic process to acetyl-CoA via 5-aminopentanamide
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA, via the intermediate 5-aminopentanamide.


go_id: GO:0033514
term: L-lysine catabolic process to acetyl-CoA via L-pipecolate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA, via the intermediate L-pipecolate.


go_id: GO:0033515
term: L-lysine catabolic process using lysine 6-aminotransferase
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including alpha-aminoadipate; in this pathway, L-lysine is converted to 2-aminoadipate-6-semialdehyde by lysine 6-aminotransferase.


go_id: GO:0033516
term: L-methionine biosynthetic process from homoserine via O-phospho-L-homoserine and cystathionine
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including homoserine, via the intermediates O-phospho-L-homoserine and cystathionine.


go_id: GO:0033517
term: myo-inositol hexakisphosphate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving phytic acid, myo-inositol hexakisphosphate, a regulator of intracellular signaling, a highly abundant animal anti-nutrient and a phosphate and mineral storage compound in plant seeds.


go_id: GO:0033519
term: phytyl diphosphate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving phytyl diphosphate, (2E)-3,7,11,15-tetramethylhexadec-2-en-1-yl trihydrogen diphosphate.


go_id: GO:0033520
term: phytol biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of phytol, (2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol.


go_id: GO:0033521
term: phytyl diphosphate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of phytyl diphosphate, (2E)-3,7,11,15-tetramethylhexadec-2-en-1-yl trihydrogen diphosphate.


go_id: GO:0033524
term: sinapate ester metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving ester derivatives of sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate.


go_id: GO:0033525
term: sinapate ester biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of ester derivates of sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate.


go_id: GO:0033526
term: tetrapyrrole biosynthetic process from glutamate
ontology: BP
definition:
The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next, from other compounds, including L-glutamate.


go_id: GO:0033527
term: tetrapyrrole biosynthetic process from glycine and succinyl-CoA
ontology: BP
definition:
The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next, from other compounds, including glycine and succinyl-CoA.


go_id: GO:0033528
term: S-methylmethionine cycle
ontology: BP
definition:
A cyclic series of interconversions involving S-methyl-L-methionine, S-adenosyl-L-homocysteine, S-adenosyl-L-methionine, L-homocysteine, and L-methionine. Converts the methionine group of adenosylmethionine back to free methionine, and may serve regulate the cellular adenosylmethionine level.


go_id: GO:0033529
term: raffinose biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of raffinose, the trisaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.


go_id: GO:0033530
term: raffinose metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving raffinose, the trisaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.


go_id: GO:0033531
term: stachyose metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving stachyose, the tetrasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.


go_id: GO:0033532
term: stachyose biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of stachyose, the tetrasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.


go_id: GO:0033533
term: verbascose metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving verbascose, the pentasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.


go_id: GO:0033534
term: verbascose biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of verbascose, the pentasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.


go_id: GO:0033535
term: ajugose metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.


go_id: GO:0033536
term: ajugose biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.


go_id: GO:0033537
term: ajugose biosynthetic process using galactinol:raffinose galactosyltransferase
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside, by a pathway in which galactinol:raffinose galactosyltransferase catalyzes chain elongation by transferring the alpha-galactosyl residue of galactinol to the oligosaccharide.


go_id: GO:0033538
term: ajugose biosynthetic process using galactan:galactan galactosyltransferase
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside, by a pathway in which galactan:galactan galactosyltransferase catalyzes chain elongation by transferring the alpha-galactosyl residue of one raffinose-family oligosaccharide to another.


go_id: GO:0033539
term: fatty acid beta-oxidation using acyl-CoA dehydrogenase
ontology: BP
definition:
A fatty acid beta-oxidation pathway in which the initial step of each oxidation cycle, which converts an acyl-CoA to a trans-2-enoyl-CoA, is catalyzed by acyl-CoA dehydrogenase; the electrons removed by oxidation pass through the respiratory chain to oxygen and leave H2O as the product. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).


go_id: GO:0033540
term: fatty acid beta-oxidation using acyl-CoA oxidase
ontology: BP
definition:
A fatty acid beta-oxidation pathway in which the initial step, which converts an acyl-CoA to a trans-2-enoyl-CoA, is catalyzed by acyl-CoA oxidase; the electrons removed by oxidation pass directly to oxygen and produce hydrogen peroxide, which is cleaved by peroxisomal catalases. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).


go_id: GO:0033541
term: fatty acid beta-oxidation, unsaturated, odd number
ontology: BP
definition:
A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on odd-numbered carbons are degraded. In this pathway, a cis-3-enoyl-CoA is generated by the core beta-oxidation pathway, and then converted to a trans-2-enoyl-CoA, which can return to the core beta-oxidation pathway for complete degradation. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).


go_id: GO:0033542
term: fatty acid beta-oxidation, unsaturated, even number
ontology: BP
definition:
A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on even-numbered carbons are degraded. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).


go_id: GO:0033543
term: fatty acid beta-oxidation, unsaturated, even number, reductase/isomerase pathway
ontology: BP
definition:
A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on even-numbered carbons are degraded. In this pathway, the intermediate 2,4-dienoyl-CoA is converted to trans-2-enoyl-CoA by 2,4-dienoyl-CoA reductase and delta3-delta2-enoyl-CoA isomerase; trans-2-enoyl-CoA returns to the core beta-oxidation pathway for further degradation. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).


go_id: GO:0033544
term: fatty acid beta-oxidation, unsaturated, even number, epimerase pathway
ontology: BP
definition:
A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on even-numbered carbons are degraded. In this pathway, the intermediate 2,4-dienoyl-CoA is converted to cis-2-enoyl-CoA through one more cycle of the core beta-oxidation pathway. Cis-2-enoyl-CoA cannot be completely degraded via the core beta-oxidation pathway because hydratation of cis-2-enoyl-CoA yields D-3-hydroxyacyl-CoA, which is not a substrate for 3-hydroxylacyl-CoA dehydrogenase. Cis-2-enoyl-CoA must enter the so-called epimerase pathway, which involves converting D-3-hydroxyacyl-CoA to L-3-hydroxyacyl-CoA by 3-hydroxylacyl-CoA epimerase or by two stereo-specific enoyl-CoA hydratases. L-3-hydroxyacyl-CoA then returns to the core beta-oxidation pathway. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).


go_id: GO:0033545
term: myo-inositol hexakisphosphate biosynthetic process, lipid-dependent
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate, phytate, by a pathway using inositol 1,4,5-trisphosphate produced from phosphatidylinositol 4,5-biphosphate hydrolysis by phospholipase C.


go_id: GO:0033546
term: myo-inositol hexakisphosphate biosynthetic process, via inositol 1,3,4-trisphosphate
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate, phytate, by a pathway using inositol 1,4,5-trisphosphate produced from phosphatidylinositol 4,5-biphosphate hydrolysis by phospholipase C; in this pathway, inositol 1,4,5-trisphosphate is first converted to inositol 1,3,4-trisphosphate, and then phosphorylated further.


go_id: GO:0033548
term: myo-inositol hexakisphosphate biosynthetic process, lipid-independent
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of phytic acid, myo-inositol hexakisphosphate, by the successively phosphorylation of myo-inositol or an inositol trisphosphate; the inositol trisphosphates that may be used by this pathway are inositol 3,4,5-trisphosphate and inositol 3,4,6trisphosphate.


go_id: GO:0033551
term: monopolin complex
ontology: CC
definition:
A protein complex required for clamping microtubule binding sites, ensuring orientation of sister kinetochores to the same pole (mono-orientation) during meiosis I. In the yeast S. cerevisiae this complex consists of Csm1p, Lrs4p, Hrr25p and Mam1p; in S. pombe Psc1 and Mde4 have been identified as subunits.


go_id: GO:0033552
term: response to vitamin B3
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B3 stimulus.


go_id: GO:0033554
term: cellular response to stress
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).


go_id: GO:0033555
term: multicellular organismal response to stress
ontology: BP
definition:
Any process that results in a change in state or activity of a multicellular organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).


go_id: GO:0033556
term: dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity
ontology: MF
definition:
Catalysis of the addition of a glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Man(7)GlcNAc(2)-PP-Dol.


go_id: GO:0033557
term: Slx1-Slx4 complex
ontology: CC
definition:
A heterodimeric protein complex that possesses an endonuclease activity that specifically cleaves certain types of branched DNA structures; because such structures often form during the replication ribosomal DNA (rDNA) repeats, the complex plays a role in the maintenance of rDNA. The subunits are known as Slx1 and Slx 4 in budding and fission yeasts, and are conserved in eukaryotes.


go_id: GO:0033559
term: unsaturated fatty acid metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving an unsaturated fatty acid, any fatty acid containing one or more double bonds between carbon atoms.


go_id: GO:0033562
term: co-transcriptional gene silencing by RNA interference machinery
ontology: BP
definition:
A process in which the RNAi machinery mediates the degradation of nascent transcripts in association with chromatin.


go_id: GO:0033563
term: dorsal/ventral axon guidance
ontology: BP
definition:
The process in which the migration of an axon growth cone is directed to a specific target site along the dorsal-ventral body axis in response to a combination of attractive and repulsive cues. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.


go_id: GO:0033564
term: anterior/posterior axon guidance
ontology: BP
definition:
The process in which the migration of an axon growth cone is directed to a specific target site along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.


go_id: GO:0033565
term: ESCRT-0 complex
ontology: CC
definition:
A protein complex required for the recycling of Golgi proteins, formation of lumenal membranes and sorting of ubiquitinated proteins into those membranes. This complex includes Vps1p and Hse1p in yeast and the Hrs and STAM proteins in mammals.


go_id: GO:0033566
term: gamma-tubulin complex localization
ontology: BP
definition:
Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location.


go_id: GO:0033567
term: DNA replication, Okazaki fragment processing
ontology: BP
definition:
The DNA metabolic process, occurring during lagging strand synthesis, by which RNA primers are removed from Okazaki fragments, the resulting gaps filled by DNA polymerization, and the ends ligated to form a continuous strand.


go_id: GO:0033568
term: lactoferrin receptor activity
ontology: MF
definition:
Combining with lactoferrin and delivering lactoferrin into the cell via endocytosis. Lactoferrin is an iron-binding glycoprotein which binds ferric iron most efficiently at low pH.


go_id: GO:0033571
term: lactoferrin transport
ontology: BP
definition:
The directed movement of lactoferrin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0033572
term: transferrin transport
ontology: BP
definition:
The directed movement of transferrin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0033573
term: high-affinity iron permease complex
ontology: CC
definition:
A protein complex composed of a multicopper ferroxidase that oxidizes Fe(II) to Fe(III), and a ferric iron permease that transports the produced Fe(III) into the cell. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.


go_id: GO:0033574
term: response to testosterone
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus.


go_id: GO:0033584
term: tyrosine biosynthetic process from chorismate via L-arogenate
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of tyrosine from other compounds, including chorismate, via the intermediate L-arogenate.


go_id: GO:0033585
term: L-phenylalanine biosynthetic process from chorismate via phenylpyruvate
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of L-phenylalanine from other compounds, including chorismate, via the intermediate phenylpyruvate.


go_id: GO:0033586
term: L-phenylalanine biosynthetic process from chorismate via L-arogenate
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of L-phenylalanine from other compounds, including chorismate, via the intermediate L-arogenate.


go_id: GO:0033588
term: elongator holoenzyme complex
ontology: CC
definition:
A heterohexameric protein complex composed two discrete heterotrimeric subcomplexes that is involved in modification of wobble nucleosides in tRNA.


go_id: GO:0033590
term: response to cobalamin
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalamin (vitamin B12) stimulus.


go_id: GO:0033591
term: response to L-ascorbic acid
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-ascorbic acid (vitamin C) stimulus.


go_id: GO:0033593
term: BRCA2-MAGE-D1 complex
ontology: CC
definition:
A heterodimeric protein complex formed of BRCA2 and MAGE-D1; may mediate the synergistic activities of the two proteins in regulating cell growth.


go_id: GO:0033594
term: response to hydroxyisoflavone
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyisoflavone stimulus.


go_id: GO:0033595
term: response to genistein
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a genistein stimulus.


go_id: GO:0033596
term: TSC1-TSC2 complex
ontology: CC
definition:
A protein complex consisting of at least tumerin and hamartin; its formation may regulate hamartin homomultimer formation. The complex acts as a GTPase activating protein (GAP) for the small GTPase (Rheb), and inhibits the TOR signaling pathway.


go_id: GO:0033597
term: mitotic checkpoint complex
ontology: CC
definition:
A multiprotein complex that functions as a mitotic checkpoint inhibitor of the anaphase-promoting complex/cyclosome (APC/C). In budding yeast this complex consists of Mad2p, Mad3p, Bub3p and Cdc20p, and in mammalian cells it consists of MAD2, BUBR1, BUB3, and CDC20.


go_id: GO:0033598
term: mammary gland epithelial cell proliferation
ontology: BP
definition:
The multiplication or reproduction of mammary gland epithelial cells, resulting in the expansion of a cell population. Mammary gland epithelial cells make up the covering of surfaces of the mammary gland. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.


go_id: GO:0033599
term: regulation of mammary gland epithelial cell proliferation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of mammary gland epithelial cell proliferation.


go_id: GO:0033600
term: negative regulation of mammary gland epithelial cell proliferation
ontology: BP
definition:
Any process that stops, prevents or reduces the rate or extent of mammary gland epithelial cell proliferation.


go_id: GO:0033601
term: positive regulation of mammary gland epithelial cell proliferation
ontology: BP
definition:
Any process that activates or increases the rate or extent of mammary gland epithelial cell proliferation.


go_id: GO:0033602
term: negative regulation of dopamine secretion
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of dopamine.


go_id: GO:0033603
term: positive regulation of dopamine secretion
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the regulated release of dopamine.


go_id: GO:0033604
term: negative regulation of catecholamine secretion
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a catecholamine.


go_id: GO:0033605
term: positive regulation of catecholamine secretion
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the regulated release of a catecholamine.


go_id: GO:0033607
term: SOD1-Bcl-2 complex
ontology: CC
definition:
A heterodimeric protein complex formed of superoxide dismutase 1 and Bcl-2. Complex formation is thought to link superoxide dismutase to an apoptotic pathway.


go_id: GO:0033610
term: oxalate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of oxalate, the organic acid ethanedioate.


go_id: GO:0033611
term: oxalate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of oxalate, the organic acid ethanedioate.


go_id: GO:0033614
term: chloroplast proton-transporting ATP synthase complex assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the chloroplast thylakoid membrane.


go_id: GO:0033615
term: mitochondrial proton-transporting ATP synthase complex assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the mitochondrial inner membrane.


go_id: GO:0033616
term: plasma membrane proton-transporting ATP synthase complex assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the plasma membrane.


go_id: GO:0033617
term: mitochondrial cytochrome c oxidase assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase) in the mitochondrial inner membrane.


go_id: GO:0033618
term: plasma membrane respiratory chain complex IV assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase) in the plasma membrane.


go_id: GO:0033619
term: membrane protein proteolysis
ontology: BP
definition:
The proteolytic cleavage of a transmembrane protein leading to the release of its intracellular or ecto-domains.


go_id: GO:0033620
term: Mei2 nuclear dot complex
ontology: CC
definition:
A ribonucleoprotein complex that forms during meiotic prophase in a fixed position in the horsetail nucleus; contains Mei2 and meiRNA. May play a role in the progression of meiosis I.


go_id: GO:0033621
term: nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts
ontology: BP
definition:
The chemical reactions and pathways resulting in the selective degradation of meiosis-specific transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein.


go_id: GO:0033622
term: integrin activation
ontology: BP
definition:
The aggregation, arrangement and bonding together of an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits, that lead to the increased affinity of the integrin for its extracellular ligands.


go_id: GO:0033626
term: positive regulation of integrin activation by cell surface receptor linked signal transduction
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of integrin activation by cell surface receptor linked signal transduction. This can occur by increased affinity of an integrin for its extracellular ligands.


go_id: GO:0033627
term: cell adhesion mediated by integrin
ontology: BP
definition:
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits.


go_id: GO:0033629
term: negative regulation of cell adhesion mediated by integrin
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of cell adhesion mediated by integrin.


go_id: GO:0033630
term: positive regulation of cell adhesion mediated by integrin
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of cell adhesion mediated by integrin.


go_id: GO:0033631
term: cell-cell adhesion mediated by integrin
ontology: BP
definition:
The attachment of one cell to another cell via an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits.


go_id: GO:0033632
term: regulation of cell-cell adhesion mediated by integrin
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of cell-cell adhesion mediated by integrin.


go_id: GO:0033633
term: negative regulation of cell-cell adhesion mediated by integrin
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of cell-cell adhesion mediated by integrin.


go_id: GO:0033634
term: positive regulation of cell-cell adhesion mediated by integrin
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of cell-cell adhesion mediated by integrin.


go_id: GO:0033635
term: modulation by symbiont of host response to abiotic stimulus
ontology: BP
definition:
Any process in which an organism modulates a change in the state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033636
term: modulation by symbiont of host response to temperature stimulus
ontology: BP
definition:
Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033637
term: modulation by symbiont of host response to cold
ontology: BP
definition:
Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033638
term: modulation by symbiont of host response to heat
ontology: BP
definition:
Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033639
term: modulation by symbiont of host response to water
ontology: BP
definition:
Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033640
term: modulation by symbiont of host response to osmotic stress
ontology: BP
definition:
Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033641
term: modulation by symbiont of host response to pH
ontology: BP
definition:
Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033642
term: modulation by symbiont of host response to gravitational stimulus
ontology: BP
definition:
Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gravitational stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033643
term: host cell part
ontology: CC
definition:
Any constituent part of a host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033644
term: host cell membrane
ontology: CC
definition:
Double layer of lipid molecules as it encloses host cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033645
term: host cell endomembrane system
ontology: CC
definition:
A collection of membranous structures involved in transport within the host cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033646
term: host intracellular part
ontology: CC
definition:
Any constituent part of the living contents of a host cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033647
term: host intracellular organelle
ontology: CC
definition:
Organized structure of distinctive morphology and function, occurring within the host cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033648
term: host intracellular membrane-bounded organelle
ontology: CC
definition:
Organized structure of distinctive morphology and function, as found in host cells, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033650
term: host cell mitochondrion
ontology: CC
definition:
A semiautonomous, self replicating organelle as found in host cells that occurs in varying numbers, shapes, and sizes in the cell cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033651
term: host cell plastid
ontology: CC
definition:
Any member of a family of organelles as found in the cytoplasm of host cells, which are membrane-bounded and contain DNA. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033652
term: host cell chloroplast
ontology: CC
definition:
A chlorophyll-containing plastid as found within host cells with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033653
term: host cell chloroplast part
ontology: CC
definition:
Any constituent part of a chloroplast as it is found in host cells and which are a chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033654
term: host cell chloroplast thylakoid membrane
ontology: CC
definition:
Any sac-like membranous structures (cisternae) in a chloroplast found in host cells, combined into stacks (grana) and present singly in the stroma (stroma thylakoids or frets) as interconnections between grana. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033655
term: host cell cytoplasm part
ontology: CC
definition:
Any constituent part of the host cell cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033656
term: modification by symbiont of host chloroplast
ontology: BP
definition:
The process in which an organism effects a change in the structure or function of host cell chloroplasts. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033657
term: modification by symbiont of host chloroplast part
ontology: BP
definition:
The process in which an organism effects a change in the structure or function of a component of the host cell chloroplast. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033658
term: modification by symbiont of host chloroplast thylakoid
ontology: BP
definition:
The process in which an organism effects a change in the structure or function of the host cell chloroplast thylakoid. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033659
term: modification by symbiont of host mitochondrion
ontology: BP
definition:
The process in which an organism effects a change in the structure or function of host cell mitochondria. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033660
term: suppression by symbiont of host resistance gene-dependent defense response
ontology: BP
definition:
Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the resistance gene-dependent defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033661
term: effector-mediated defense to host-produced reactive oxygen species
ontology: BP
definition:
A process mediated by a molecule secreted by a symbiont that results in the suppression of reactive oxygen species produced by the host as part of its innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033668
term: negative regulation by symbiont of host apoptotic process
ontology: BP
definition:
Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033670
term: regulation of NAD+ kinase activity
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of NAD kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an NAD molecule.


go_id: GO:0033671
term: negative regulation of NAD+ kinase activity
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of NAD kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an NAD molecule.


go_id: GO:0033672
term: positive regulation of NAD+ kinase activity
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of NAD kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an NAD molecule.


go_id: GO:0033673
term: negative regulation of kinase activity
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.


go_id: GO:0033674
term: positive regulation of kinase activity
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.


go_id: GO:0033675
term: pericanalicular vesicle
ontology: CC
definition:
A membrane-bounded vesicle found near the apical, or pericanalicular, membrane of a hepatocyte; contains proteins involved in bile salt transport and other fluid and solute transport processes.


go_id: GO:0033677
term: DNA/RNA helicase activity
ontology: MF
definition:
Unwinding of a DNA/RNA duplex, i.e. a double helix in which a strand of DNA pairs with a complementary strand of RNA, driven by ATP hydrolysis.


go_id: GO:0033683
term: nucleotide-excision repair, DNA incision
ontology: BP
definition:
A process that results in the endonucleolytic cleavage of the damaged strand of DNA. The incision occurs at the junction of single-stranded DNA and double-stranded DNA that is formed when the DNA duplex is unwound.


go_id: GO:0033684
term: regulation of luteinizing hormone secretion
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the regulated release of luteinizing hormone.


go_id: GO:0033685
term: negative regulation of luteinizing hormone secretion
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of luteinizing hormone.


go_id: GO:0033686
term: positive regulation of luteinizing hormone secretion
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the regulated release of luteinizing hormone.


go_id: GO:0033687
term: osteoblast proliferation
ontology: BP
definition:
The multiplication or reproduction of osteoblasts, resulting in the expansion of an osteoblast cell population. An osteoblast is a bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone.


go_id: GO:0033691
term: sialic acid binding
ontology: MF
definition:
Binding to a sialic acid, a N- or O- substituted derivative of neuraminic acid, a nine carbon monosaccharide. Sialic acids often occur in polysaccharides, glycoproteins, and glycolipids in animals and bacteria.


go_id: GO:0033692
term: cellular polysaccharide biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of polysaccharides, polymers of many (typically more than 10) monosaccharide residues linked glycosidically, occurring at the level of an individual cell.


go_id: GO:0033693
term: neurofilament bundle assembly
ontology: BP
definition:
The assembly of neurofilaments into bundles, in which the filaments are longitudinally oriented, with numerous crossbridges between them. Neurofilament bundles may be cross-linked to each other, to membrane-bounded organelles or other cytoskeletal structures such as microtubules.


go_id: GO:0033694
term: oxidoreductase activity, acting on the CH-NH group of donors, iron-sulfur protein as acceptor
ontology: MF
definition:
Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces an iron-sulfur protein.


go_id: GO:0033695
term: oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor
ontology: MF
definition:
Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces a quinone or similar acceptor molecule.


go_id: GO:0033698
term: Rpd3L complex
ontology: CC
definition:
A histone deacetylase complex which deacetylates histones preferentially in promoter regions. Composed of a catalytic histone deacetylase subunit, an Sds-3 family protein, a SIN3 family co-repressor, a WD repeat protein, and a zf- PHD finger (Clr6, Sds3, Pst1, Prw1, Png2 in Schizosaccharomyces pombe; Rpd3p, Sin3p, Ume1p, Pho23p, Sap30p, Sds3p, Cti6p, Rxt2p, Rxt3p, Dep1p, Ume6p and Ash1p in Saccharomyces cerevisiae).


go_id: GO:0033699
term: DNA 5'-adenosine monophosphate hydrolase activity
ontology: MF
definition:
Catalysis of the reaction: 5'-AMP-DNA + H2O = AMP + DNA; nucleophilic release of a covalently linked adenylate residue from a DNA strand, leaving a 5' phosphate terminus.


go_id: GO:0033701
term: dTDP-galactose 6-dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: dTDP-D-galactose + 2 NADP+ + H2O = dTDP-D-galacturonate + 2 NADPH + 2 H+.


go_id: GO:0033703
term: 3beta-hydroxy-5beta-steroid dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 3beta-hydroxy-5beta-pregnane-20-one + NADP(+) = 5beta-pregnan-3,20-dione + H(+) + NADPH.


go_id: GO:0033704
term: 3beta-hydroxy-5alpha-steroid dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 3beta-hydroxy-5alpha-pregnane-20-one + NADP(+) = 5alpha-pregnane-3,20-dione + H(+) + NADPH.


go_id: GO:0033705
term: GDP-4-dehydro-6-deoxy-D-mannose reductase activity
ontology: MF
definition:
Catalysis of the reaction: GDP-6-deoxy-D-mannose + NAD(P)+ = GDP-4-dehydro-6-deoxy-D-mannose + NAD(P)H + H+.


go_id: GO:0033707
term: 3''-deamino-3''-oxonicotianamine reductase activity
ontology: MF
definition:
Catalysis of the reaction: 2'-deoxymugineic acid + NAD(P)+ = 3''-deamino-3''-oxonicotianamine + NAD(P)H + H+.


go_id: GO:0033708
term: isocitrate-homoisocitrate dehydrogenase activity
ontology: MF
definition:
Catalysis of the reactions: isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH, and (1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate + NAD+ = 2-oxoadipate + CO2 + NADH + H+.


go_id: GO:0033711
term: 4-phosphoerythronate dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 4-phospho-D-erythronate + NAD(+) = (R)-3-hydroxy-2-oxo-4-phosphonooxybutanoate + H(+) + NADH.


go_id: GO:0033712
term: 1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming) activity
ontology: MF
definition:
Catalysis of the reaction: 1,5-anhydro-D-mannitol + NADP(+) = 1,5-anhydro-D-fructose + H(+) + NADPH.


go_id: GO:0033715
term: nucleoside oxidase activity
ontology: MF
definition:
Catalysis of the reactions: inosine + O2 = 9-riburonosylhypoxanthine + 2 H2O; (1a) 2 inosine + O2 = 2 5'-dehydroinosine + 2 H2O, and (1b) 2 5'-dehydroinosine + O2 = 2 9-riburonosylhypoxanthine + 2 H2O.


go_id: GO:0033718
term: pyranose dehydrogenase (acceptor) activity
ontology: MF
definition:
Catalysis of the reactions: pyranose + acceptor = 2-dehydropyranose (or 3-dehydropyranose or 2,3-didehydropyranose) + reduced acceptor, and a pyranoside + acceptor = a 3-dehydropyranoside (or 3,4-didehydropyranoside) + reduced acceptor.


go_id: GO:0033719
term: 2-oxo-acid reductase activity
ontology: MF
definition:
Catalysis of the reaction: a (2R)-hydroxy-carboxylate + acceptor = a 2-oxo-carboxylate + reduced acceptor.


go_id: GO:0033720
term: (S)-mandelate dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: (S)-2-hydroxy-2-phenylacetate + acceptor = 2-oxo-2-phenylacetate + reduced acceptor.


go_id: GO:0033726
term: aldehyde ferredoxin oxidoreductase activity
ontology: MF
definition:
Catalysis of the reaction: an aldehyde + H2O + 2 oxidized ferredoxin = an acid + 2 H+ + 2 reduced ferredoxin.


go_id: GO:0033732
term: pyrroloquinoline-quinone synthase activity
ontology: MF
definition:
Catalysis of the reaction: 6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O(2) = 2 H(2)O + 2 H(2)O(2) + H(+) + pyrroloquinoline quinone.


go_id: GO:0033734
term: (R)-benzylsuccinyl-CoA dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: (R)-2-benzylsuccinyl-CoA + 2 electron-transferring flavoprotein = (E)-2-benzylidenesuccinyl-CoA + 2 reduced electron-transferring flavoprotein.


go_id: GO:0033738
term: methylenetetrahydrofolate reductase (ferredoxin) activity
ontology: MF
definition:
Catalysis of the reaction: 5-methyltetrahydrofolate + oxidized ferredoxin = 5,10-methylenetetrahydrofolate + reduced ferredoxin.


go_id: GO:0033739
term: preQ1 synthase activity
ontology: MF
definition:
Catalysis of the reaction: 7-aminomethyl-7-deazaguanine + 2 NADP(+) = 7-cyano-7-deazaguanine + 3 H(+) + 2 NADPH.


go_id: GO:0033740
term: hydroxylamine oxidoreductase activity
ontology: MF
definition:
Catalysis of the reactions: hydroxylamine + NH3 = hydrazine + H2O, and hydrazine + acceptor = N2 + reduced acceptor.


go_id: GO:0033741
term: adenylyl-sulfate reductase (glutathione) activity
ontology: MF
definition:
Catalysis of the reaction: AMP + glutathione disulfide + H(+) + sulfite = 5'-adenylyl sulfate + 2 glutathione.


go_id: GO:0033743
term: peptide-methionine (R)-S-oxide reductase activity
ontology: MF
definition:
Catalysis of the reaction: peptide-L-methionine + H(2)O + thioredoxin disulfide = peptide-L-methionine (R)-S-oxide + thioredoxin. Can act on oxidized methionine in peptide linkage with specificity for the R enantiomer. Thioredoxin disulfide is the oxidized form of thioredoxin.


go_id: GO:0033744
term: L-methionine:thioredoxin-disulfide S-oxidoreductase activity
ontology: MF
definition:
Catalysis of the reaction: L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin.


go_id: GO:0033745
term: L-methionine-(R)-S-oxide reductase activity
ontology: MF
definition:
Catalysis of the reaction: L-methionine + thioredoxin disulfide + H2O = L-methionine (R)-S-oxide + thioredoxin.


go_id: GO:0033746
term: histone H3-methyl-arginine-2 demethylase activity
ontology: MF
definition:
Catalysis of the removal of the methyl group from a modified arginine residue at position 2 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.


go_id: GO:0033749
term: histone H3-methyl-arginine-3 demethylase activity
ontology: MF
definition:
Catalysis of the removal of the methyl group from a modified arginine residue at position 3 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.


go_id: GO:0033754
term: indoleamine 2,3-dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: tryptophan + O2 = N-formylkynurenine. The product of the reaction depends on the substrate; D-tryptophan produces N-formyl-D-kynurenine, and L-tryptophan produces N-formyl-L-kynurenine.


go_id: GO:0033757
term: glucoside 3-dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: sucrose + acceptor = 3-dehydro-alpha-D-glucosyl-beta-D-fructofuranoside + reduced acceptor.


go_id: GO:0033758
term: clavaminate synthase activity
ontology: MF
definition:
Catalysis of the reactions: deoxyamidinoproclavaminate + 2-oxoglutarate + O2 = amidinoproclavaminate + succinate + CO2 + H2O; proclavaminate + 2-oxoglutarate + O2 = dihydroclavaminate + succinate + CO2 + 2 H2O; and dihydroclavaminate + 2-oxoglutarate + O2 = clavaminate + succinate + CO2 + 2 H2O.


go_id: GO:0033760
term: 2'-deoxymugineic-acid 2'-dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 2'-deoxymugineate + 2-oxoglutarate + O(2) = CO(2) + H(+) + mugineate + succinate.


go_id: GO:0033761
term: mugineic-acid 3-dioxygenase activity
ontology: MF
definition:
Catalysis of the reactions: mugineic acid + 2-oxoglutarate + O2 = 3-epihydroxymugineic acid + succinate + CO2.


go_id: GO:0033762
term: response to glucagon
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus.


go_id: GO:0033763
term: proline 3-hydroxylase activity
ontology: MF
definition:
Catalysis of the reaction: L-proline + 2-oxoglutarate + O2 = cis-3-hydroxy-L-proline + succinate + CO2.


go_id: GO:0033764
term: steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
ontology: MF
definition:
Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP, and in which one substrate is a sterol derivative.


go_id: GO:0033765
term: steroid dehydrogenase activity, acting on the CH-CH group of donors
ontology: MF
definition:
Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor, and in which one substrate is a sterol derivative.


go_id: GO:0033766
term: 2-hydroxyquinoline 8-monooxygenase activity
ontology: MF
definition:
Catalysis of the reaction: H(+) + NADH + O(2) + quinolin-2-ol = H(2)O + NAD(+) + quinoline-2,8-diol.


go_id: GO:0033767
term: 4-hydroxyacetophenone monooxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 4'-hydroxyacetophenone + H(+) + NADPH + O(2) = 4-hydroxyphenyl acetate + H(2)O + NADP(+).


go_id: GO:0033768
term: SUMO-targeted ubiquitin ligase complex
ontology: CC
definition:
A nuclear ubiquitin ligase complex that specifically targets SUMOylated proteins; the complex is formed of homodimers or heterodimers of RNF4 family ubiquitin ligases and is conserved in eukaryotes.


go_id: GO:0033769
term: glyceollin synthase activity
ontology: MF
definition:
Catalysis of the reactions: 2-dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan + NADPH + H+ + O2 = glyceollin + NADP+ + 2 H2O, and 4-dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan + NADPH + H+ + O2 = glyceollin + NADP+ + 2 H2O.


go_id: GO:0033770
term: 2-hydroxyisoflavanone synthase activity
ontology: MF
definition:
Catalysis of the reactions: liquiritigenin + O2 + [reduced NADPH--hemoprotein reductase] = 2,4',7-trihydroxyisoflavanone + H2O + [oxidized NADPH--hemoprotein reductase] and (2S)-naringenin + O2 + [reduced NADPH--hemoprotein reductase] = 2,4',5,7-tetrahydroxyisoflavanone + H2O + [oxidized NADPH--hemoprotein reductase].


go_id: GO:0033772
term: flavonoid 3',5'-hydroxylase activity
ontology: MF
definition:
Catalysis of the reactions: a flavanone + NADPH + H+ + O2 = a 3'-hydroxyflavanone + NADP+ + H2O, and a 3'-hydroxyflavanone + NADPH + H+ + O2 = a 3',5'-dihydroxyflavanone + NADP+ + H2O.


go_id: GO:0033773
term: isoflavone 2'-hydroxylase activity
ontology: MF
definition:
Catalysis of the reaction: an isoflavone + O2 + reduced [NADPH-hemoprotein reductase] = a 2'-hydroxyisoflavone + H+ + H2O + oxidized [NADPH-hemoprotein reductase].


go_id: GO:0033774
term: basal labyrinth
ontology: CC
definition:
A region in the lower half of some cells formed from extensive infoldings of the basal plasma membrane; includes cytoplasm adjacent to the infolded membrane.


go_id: GO:0033777
term: lithocholate 6beta-hydroxylase activity
ontology: MF
definition:
Catalysis of the reaction: H(+) + lithocholate + NADPH + O(2) = 6-beta-hydroxylithocholate + H(2)O + NADP(+).


go_id: GO:0033778
term: 7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity
ontology: MF
definition:
Catalysis of the reaction: 7alpha-hydroxycholest-4-en-3-one + H(+) + NADPH + O(2) = 7alpha,12alpha-dihydroxycholest-4-en-3-one + H(2)O + NADP(+).


go_id: GO:0033779
term: 5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase activity
ontology: MF
definition:
Catalysis of the reaction: 5beta-cholestane-3alpha,7alpha-diol + H(+) + NADPH + O(2) = 5beta-cholestane-3alpha,7alpha,12alpha-triol + H(2)O + NADP(+).


go_id: GO:0033780
term: taurochenodeoxycholate 6alpha-hydroxylase activity
ontology: MF
definition:
Catalysis of the reactions: taurochenodeoxycholate + NADPH + H+ + O2 = taurohyocholate + NADP+ + H2O, and lithocholate + NADPH + H+ + O2 = hyodeoxycholate + NADP+ + H2O.


go_id: GO:0033781
term: cholesterol 24-hydroxylase activity
ontology: MF
definition:
Catalysis of the reaction: cholesterol + H(+) + NADPH + O(2) = (24S)-24-hydroxycholesterol + H(2)O + NADP(+).


go_id: GO:0033782
term: 24-hydroxycholesterol 7alpha-hydroxylase activity
ontology: MF
definition:
Catalysis of the reaction: (24S)-hydroxycholesterol + O2 + reduced [NADPH-hemoprotein reductase] = (24S)-7alpha-dihydroxycholesterol + H+ + H2O + oxidized [NADPH-hemoprotein reductase].


go_id: GO:0033783
term: 25-hydroxycholesterol 7alpha-hydroxylase activity
ontology: MF
definition:
Catalysis of the reactions: cholest-5-ene-3beta,25-diol + NADPH + H+ + O2 = cholest-5-ene-3beta,7alpha,25-triol + NADP+ + H2O, and cholest-5-ene-3beta,27-diol + NADPH + H+ + O2 = cholest-5-ene-3beta,7alpha,27-triol + NADP+ + H2O.


go_id: GO:0033784
term: senecionine N-oxygenase activity
ontology: MF
definition:
Catalysis of the reaction: H(+) + NADPH + O(2) + senecionine = H(2)O + NADP(+) + senecionine N-oxide.


go_id: GO:0033785
term: heptose 7-phosphate kinase activity
ontology: MF
definition:
Catalysis of the reaction: D-alpha,beta-D-heptose-7-phosphate + ATP = D-beta-D-heptose-1,7-bisphosphate + ADP.


go_id: GO:0033787
term: cyanocobalamin reductase (cyanide-eliminating) activity
ontology: MF
definition:
Catalysis of the reaction: cob(I)alamin + hydrogen cyanide + NADP(+) = cyanocob(III)alamin + H(+) + NADPH.


go_id: GO:0033788
term: leucoanthocyanidin reductase activity
ontology: MF
definition:
Catalysis of the reaction: (2R,3S)-catechin + NADP+ + H2O = 2,3-trans-3,4-cis-leucocyanidin + NADPH + H+.


go_id: GO:0033789
term: phenylacetyl-CoA dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 2 1,4-benzoquinone + H(2)O + phenylacetyl-CoA = 2 hydroquinone + phenylglyoxylyl-CoA.


go_id: GO:0033790
term: hydroxymethylfurfural reductase activity
ontology: MF
definition:
Catalysis of the reaction: 5-hydroxymethylfurfural + NAD(P)H + H+ = 2,5-bis-hydroxymethylfuran + NAD(P)+.


go_id: GO:0033791
term: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity
ontology: MF
definition:
Catalysis of the reaction: (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + H2O + acceptor = (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA + reduced acceptor.


go_id: GO:0033792
term: 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase activity
ontology: MF
definition:
Catalysis of the reactions: a 3alpha-hydroxy bile acid CoA + NAD+ =  a 3-oxo bile acid CoA + H+ + NADH.


go_id: GO:0033793
term: aureusidin synthase activity
ontology: MF
definition:
Catalysis of the reactions: 2',4,4',6'-tetrahydroxychalcone + O2 = aureusidin + H2O, and 2',3,4,4',6'-pentahydroxychalcone + 1/2 O2 = aureusidin + H2O.


go_id: GO:0033794
term: sarcosine reductase activity
ontology: MF
definition:
Catalysis of the reaction: acetyl phosphate + methylamine + thioredoxin disulfide = N-methylglycine + phosphate + thioredoxin.


go_id: GO:0033795
term: betaine reductase activity
ontology: MF
definition:
Catalysis of the reaction: acetyl phosphate + trimethylamine + thioredoxin disulfide = N,N,N-trimethylglycine + phosphate + thioredoxin.


go_id: GO:0033799
term: myricetin 3'-O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + myricetin = S-adenosyl-L-homocysteine + laricitrin.


go_id: GO:0033800
term: isoflavone 7-O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + a 7-hydroxyisoflavone = S-adenosyl-L-homocysteine + a 7-methoxyisoflavone.


go_id: GO:0033801
term: vitexin 2''-O-rhamnoside 7-O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + vitexin 2''-O-beta-L-rhamnoside = S-adenosyl-L-homocysteine + 7-O-methylvitexin 2''-O-beta-L-rhamnoside.


go_id: GO:0033802
term: isoliquiritigenin 2'-O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + isoliquiritigenin = 2'-O-methylisoliquiritigenin + S-adenosyl-L-homocysteine + H(+).


go_id: GO:0033803
term: kaempferol 4'-O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + kaempferol = S-adenosyl-L-homocysteine + H(+) + kaempferide.


go_id: GO:0033807
term: icosanoyl-CoA synthase activity
ontology: MF
definition:
Catalysis of the reaction: stearoyl-CoA + malonyl-CoA + 2 NAD(P)H + 2 H+ = icosanoyl-CoA + CO2 + 2 NAD(P)+.


go_id: GO:0033808
term: 6'-deoxychalcone synthase activity
ontology: MF
definition:
Catalysis of the reaction: 3 malonyl-CoA + 4-coumaroyl-CoA + NADPH + H+ = 4 CoA + isoliquiritigenin + 3 CO2 + NADP+ + H2O.


go_id: GO:0033809
term: anthocyanin 6''-O-malonyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: malonyl-CoA + an anthocyanidin 3-O-beta-D-glucoside = CoA + an anthocyanidin 3-O-(6-O-malonyl-beta-D-glucoside).


go_id: GO:0033810
term: anthocyanin 5-O-glucoside 6'''-O-malonyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: malonyl-CoA + pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside = CoA + 4'''-demalonylsalvianin.


go_id: GO:0033811
term: flavonol-3-O-triglucoside O-coumaroyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: 4-coumaroyl-CoA + a flavonol 3-O-[beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside] = CoA + a flavonol 3-O-[6-(4-coumaroyl)-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside].


go_id: GO:0033814
term: propanoyl-CoA C-acyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA + propanoyl-CoA = CoA + 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestanoyl-CoA.


go_id: GO:0033816
term: diaminobutyrate acetyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: L-2,4-diaminobutyrate + acetyl-CoA = N(4)-acetyl-L-2,4-diaminobutyrate + CoA + H(+).


go_id: GO:0033818
term: beta-ketoacyl-acyl-carrier-protein synthase III activity
ontology: MF
definition:
Catalysis of the reaction: acetyl-CoA + malonyl-[acyl-carrier protein] = acetoacyl-[acyl-carrier protein] + CoA + CO2.


go_id: GO:0033819
term: lipoyl(octanoyl) transferase activity
ontology: MF
definition:
Catalysis of the reaction: L-lysyl-[protein] + octanoyl-[ACP] = H+ + holo-[ACP] + N6-octanoyl-L-lysyl-[protein].


go_id: GO:0033820
term: DNA alpha-glucosyltransferase activity
ontology: MF
definition:
Catalysis of the transfer of an alpha-D-glucosyl residue from UDP-glucose to a hydroxymethylcytosine residue in DNA.


go_id: GO:0033821
term: DNA beta-glucosyltransferase activity
ontology: MF
definition:
Catalysis of the transfer of a beta-D-glucosyl residue from UDP-glucose to a hydroxymethylcytosine residue in DNA.


go_id: GO:0033822
term: glucosyl-DNA beta-glucosyltransferase activity
ontology: MF
definition:
Catalysis of the transfer of a beta-D-glucosyl residue from UDP-glucose to a glucosylhydroxymethylcytosine residue in DNA.


go_id: GO:0033823
term: procollagen glucosyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: UDP-glucose + 5-(D-galactosyloxy)-L-lysine-procollagen = UDP + 1,2-D-glucosyl-5-D-(galactosyloxy)-L-lysine-procollagen.


go_id: GO:0033824
term: alternansucrase activity
ontology: MF
definition:
Catalysis of the transfer of an alpha-D-glucosyl residue from sucrose to alternately the 6-position and the 3-position of the non-reducing terminal residue of an alpha-D-glucan, thus producing a glucan having alternating alpha-1,6- and alpha-1,3-linkages.


go_id: GO:0033825
term: oligosaccharide 4-alpha-D-glucosyltransferase activity
ontology: MF
definition:
Catalysis of the transfer of the non-reducing terminal alpha-D-glucose residue from a 1,4-alpha-D-glucan to the 4-position of an alpha-D-glucan, thus bringing about the hydrolysis of oligosaccharides.


go_id: GO:0033826
term: xyloglucan 4-glucosyltransferase activity
ontology: MF
definition:
Catalysis of the transfer of a beta-D-glucosyl residue from UDP-glucose on to a glucose residue in xyloglucan, forming a beta-1,4-D-glucosyl-D-glucose linkage.


go_id: GO:0033827
term: high-mannose-oligosaccharide beta-1,4-N-acetylglucosaminyltransferase activity
ontology: MF
definition:
Catalysis of the transfer of an N-acetyl-D-glucosamine residue from UDP-N-acetyl-D-glucosamine to the 4-position of a mannose linked alpha-1,6 to the core mannose of high-mannose oligosaccharides produced by Dictyostelium discoideum.


go_id: GO:0033828
term: glucosylglycerol-phosphate synthase activity
ontology: MF
definition:
Catalysis of the reaction: sn-glycerol 3-phosphate + ADP-glucose = 2-O-(beta-D-glucosyl)-sn-glycerol 3-phosphate + ADP + H(+).


go_id: GO:0033829
term: O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity
ontology: MF
definition:
Catalysis of the transfer of a beta-D-GlcNAc residue from UDP-D-GlcNAc to the fucose residue of a fucosylated protein acceptor.


go_id: GO:0033830
term: Skp1-protein-hydroxyproline N-acetylglucosaminyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: UDP-N-acetylglucosamine + Skp1-protein-hydroxyproline = UDP + Skp1-protein-O-(N-acetyl-D-glucosaminyl)hydroxyproline.


go_id: GO:0033832
term: alpha,alpha-trehalose phosphorylase (configuration-retaining) activity
ontology: MF
definition:
Catalysis of the reaction: alpha,alpha-trehalose + phosphate = alpha-D-glucose + alpha-D-glucose 1-phosphate.


go_id: GO:0033835
term: flavanone 7-O-glucoside 2''-O-beta-L-rhamnosyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: UDP-L-rhamnose + a flavanone 7-O-glucoside = UDP + a flavanone 7-O-[beta-L-rhamnosyl-(1->2)-beta-D-glucoside].


go_id: GO:0033837
term: anthocyanin 3'-O-beta-glucosyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: UDP-glucose + an anthocyanin = UDP + an anthocyanin 3'-O-beta-D-glucoside.


go_id: GO:0033838
term: flavonol-3-O-glucoside glucosyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: UDP-glucose + a flavonol 3-O-beta-D-glucoside = UDP + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside.


go_id: GO:0033839
term: flavonol-3-O-glycoside glucosyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: UDP-glucose + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside = UDP + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside.


go_id: GO:0033841
term: 6G-fructosyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: [1-beta-D-fructofuranosyl-(2->1)-]m+1 alpha-D-glucopyranoside + [1-beta-D-fructofuranosyl-(2->1)-]n+1 alpha-D-glucopyranoside = [1-beta-D-fructofuranosyl-(2->1)-]m alpha-D-glucopyranoside + [1-beta-D-fructofuranosyl-(2->1)-]n+1 beta-D-fructofuranosyl-(2->6)-alpha-D-glucopyranoside (m > 0; n >= 0).


go_id: GO:0033842
term: N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + N-acetyl-beta-D-glucosaminyl group = UDP + N-acetyl-beta-D-galactosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl group.


go_id: GO:0033843
term: xyloglucan 6-xylosyltransferase activity
ontology: MF
definition:
Catalysis of the transfer of an alpha-D-xylosyl residue from UDP-D-xylose to a glucose residue in xyloglucan, forming an alpha-1,6-D-xylosyl-D-glucose linkage.


go_id: GO:0033844
term: galactose-6-sulfurylase activity
ontology: MF
definition:
Catalysis of the elimination of sulfate from the D-galactose 6-sulfate residues of porphyran, producing 3,6-anhydrogalactose residues.


go_id: GO:0033845
term: hydroxymethylfurfural reductase (NADPH) activity
ontology: MF
definition:
Catalysis of the reaction: 5-hydroxymethylfurfural + NADPH + H+ = 2,5-bis-hydroxymethylfuran + NADP+.


go_id: GO:0033846
term: adenosyl-fluoride synthase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + fluoride = 5'-deoxy-5'-fluoroadenosine + L-methionine.


go_id: GO:0033848
term: N2-(2-carboxyethyl)arginine synthase activity
ontology: MF
definition:
Catalysis of the reaction: D-glyceraldehyde 3-phosphate + L-arginine = N(2)-(2-carboxyethyl)-L-arginine + H(+) + phosphate.


go_id: GO:0033849
term: chrysanthemyl diphosphate synthase activity
ontology: MF
definition:
Catalysis of the reaction: 2 dimethylallyl diphosphate = (R,R)-chrysanthemyl diphosphate + diphosphate.


go_id: GO:0033850
term: Z-farnesyl diphosphate synthase activity
ontology: MF
definition:
Catalysis of the reaction: geranyl diphosphate + isopentenyl diphosphate = 2-cis,6-trans-farnesyl diphosphate + diphosphate.


go_id: GO:0033852
term: thyroid-hormone transaminase activity
ontology: MF
definition:
Catalysis of the reaction: 2-oxoglutarate + 3,5,3'-triiodo-L-thyronine = 3,5,3'-triiodothyropyruvate + L-glutamate.


go_id: GO:0033855
term: nicotianamine aminotransferase activity
ontology: MF
definition:
Catalysis of the reaction: 2-oxoglutarate + nicotianamine = 3''-deamino-3''-oxonicotianamine + L-glutamate.


go_id: GO:0033856
term: pyridoxine 5'-phosphate synthase activity
ontology: MF
definition:
Catalysis of the reaction: 1-deoxy-D-xylulose 5-phosphate + 3-amino-2-oxopropyl phosphate = 2 H(2)O + H(+) + phosphate + pyridoxine 5'-phosphate.


go_id: GO:0033857
term: diphosphoinositol-pentakisphosphate kinase activity
ontology: MF
definition:
Catalysis of the reaction: ATP + 1D-myo-inositol 5-diphosphate pentakisphosphate = ADP + 1D-myo-inositol bisdiphosphate tetrakisphosphate.


go_id: GO:0033858
term: N-acetylgalactosamine kinase activity
ontology: MF
definition:
Catalysis of the reaction: ATP + N-acetyl-D-galactosamine = ADP + N-acetyl-alpha-D-galactosamine 1-phosphate.


go_id: GO:0033859
term: furaldehyde metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving furaldehyde, a furan ring-containing aldehyde compound which can be formed from the thermal decomposition of biomass.


go_id: GO:0033863
term: ribose 1,5-bisphosphate phosphokinase activity
ontology: MF
definition:
Catalysis of the reaction: D-ribose 1,5-diphosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + ADP + H(+).


go_id: GO:0033865
term: nucleoside bisphosphate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.


go_id: GO:0033866
term: nucleoside bisphosphate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.


go_id: GO:0033867
term: Fas-activated serine/threonine kinase activity
ontology: MF
definition:
Catalysis of the reaction: ATP + Fas-activated serine/threonine protein = ADP + Fas-activated serine/threonine phosphoprotein.


go_id: GO:0033869
term: nucleoside bisphosphate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.


go_id: GO:0033870
term: thiol sulfotransferase activity
ontology: MF
definition:
Catalysis of the reaction: 3'-phosphoadenylyl sulfate + a thiol = adenosine 3',5'-bisphosphate + an S-alkyl thiosulfate.


go_id: GO:0033871
term: [heparan sulfate]-glucosamine 3-sulfotransferase 2 activity
ontology: MF
definition:
Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate; modifies selected glucosamine residues preceded by GlcA2S.


go_id: GO:0033872
term: [heparan sulfate]-glucosamine 3-sulfotransferase 3 activity
ontology: MF
definition:
Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate.


go_id: GO:0033873
term: petromyzonol sulfotransferase activity
ontology: MF
definition:
Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + 5alpha-cholane-3alpha,7alpha,12alpha,24-tetrol = 3alpha,7alpha,12alpha-trihydroxy-5alpha-cholan-24-yl sulfate + adenosine 3',5'-diphosphate + H(+).


go_id: GO:0033874
term: scymnol sulfotransferase activity
ontology: MF
definition:
Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + 5beta-scymnol = 5beta-scymnol sulfate + adenosine 3',5'-diphosphate + H(+).


go_id: GO:0033875
term: ribonucleoside bisphosphate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving a ribonucleoside bisphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.


go_id: GO:0033876
term: glycochenodeoxycholate sulfotransferase activity
ontology: MF
definition:
Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + glycochenodeoxycholate = adenosine 3',5'-diphosphate + glycochenodeoxycholate 7-sulfate + H(+).


go_id: GO:0033877
term: succinyl-CoA:(R)-benzylsuccinate CoA-transferase activity
ontology: MF
definition:
Catalysis of the reaction: (R)-2-benzylsuccinate + succinyl-CoA = (R)-2-benzylsuccinyl-CoA + succinate.


go_id: GO:0033878
term: hormone-sensitive lipase activity
ontology: MF
definition:
Catalysis of the reactions: diacylglycerol + H2O = monoacylglycerol + a carboxylate; triacylglycerol + H2O = diacylglycerol + a carboxylate; and monoacylglycerol + H2O = glycerol + a carboxylate.


go_id: GO:0033879
term: acetylajmaline esterase activity
ontology: MF
definition:
Catalysis of the reactions: 17-O-acetylajmaline + H2O = ajmaline + acetate, and 17-O-acetylnorajmaline + H2O = norajmaline + acetate.


go_id: GO:0033885
term: 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity
ontology: MF
definition:
Catalysis of the reaction: (9S,10S)-10-hydroxy-9-(phosphonooxy)octadecanoate + H(2)O = (9S,10S)-9,10-dihydroxyoctadecanoate + phosphate.


go_id: GO:0033886
term: cellulose-polysulfatase activity
ontology: MF
definition:
Catalysis of the hydrolysis of the 2- and 3-sulfate groups of the polysulfates of cellulose and charonin.


go_id: GO:0033887
term: chondro-4-sulfatase activity
ontology: MF
definition:
Catalysis of the reaction: 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine 4-sulfate + H(2)O = 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine + H(+) + sulfate.


go_id: GO:0033888
term: chondro-6-sulfatase activity
ontology: MF
definition:
Catalysis of the reaction: 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine 6-sulfate + H(2)O = 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine + H(+) + sulfate.


go_id: GO:0033889
term: N-sulfoglucosamine-3-sulfatase activity
ontology: MF
definition:
Catalysis of the hydrolysis of the 3-sulfate groups of the N-sulfo-D-glucosamine 3-O-sulfate units of heparin.


go_id: GO:0033890
term: ribonuclease D activity
ontology: MF
definition:
Catalysis of the exonucleolytic cleavage that removes extra residues from the 3'-terminus of tRNA to produce 5'-mononucleotides.


go_id: GO:0033891
term: CC-preferring endodeoxyribonuclease activity
ontology: MF
definition:
Catalysis of the endonucleolytic cleavage to give 5'-phosphooligonucleotide end-products, with a preference for cleavage within the sequence CC.


go_id: GO:0033893
term: ribonuclease IV activity
ontology: MF
definition:
Catalysis of the endonucleolytic cleavage of poly(A) to fragments terminated by 3'-hydroxy and 5'-phosphate groups.


go_id: GO:0033895
term: ribonuclease [poly-(U)-specific] activity
ontology: MF
definition:
Catalysis of the endonucleolytic cleavage of poly(U) to fragments terminated by 3'-hydroxy and 5'-phosphate groups.


go_id: GO:0033896
term: ribonuclease IX activity
ontology: MF
definition:
Catalysis of the endonucleolytic cleavage of poly(U) or poly(C) to fragments terminated by 3'-hydroxy and 5'-phosphate groups.


go_id: GO:0033897
term: ribonuclease T2 activity
ontology: MF
definition:
Catalysis of the two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates.


go_id: GO:0033899
term: ribonuclease U2 activity
ontology: MF
definition:
Catalysis of the two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in Ap or Gp with 2',3'-cyclic phosphate intermediates.


go_id: GO:0033900
term: ribonuclease F activity
ontology: MF
definition:
Catalysis of the endonucleolytic cleavage of RNA precursor into two, leaving 5'-hydroxy and 3'-phosphate groups.


go_id: GO:0033902
term: rRNA endonuclease activity
ontology: MF
definition:
Catalysis of the hydrolysis of the phosphodiester linkage between guanosine and adenosine residues at one specific position in 28S rRNA from rat ribosomes.


go_id: GO:0033906
term: hyaluronoglucuronidase activity
ontology: MF
definition:
Catalysis of the random hydrolysis of 1,3-linkages between beta-D-glucuronate and N-acetyl-D-glucosamine residues in hyaluronate.


go_id: GO:0033908
term: beta-L-rhamnosidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of terminal, non-reducing beta-L-rhamnose residues in beta-L-rhamnosides.


go_id: GO:0033909
term: fucoidanase activity
ontology: MF
definition:
Catalysis of the endohydrolysis of 1,2-alpha-L-fucoside linkages in fucoidan without release of sulfate.


go_id: GO:0033910
term: glucan 1,4-alpha-maltotetraohydrolase activity
ontology: MF
definition:
Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltotetraose residues from the non-reducing chain ends.


go_id: GO:0033911
term: mycodextranase activity
ontology: MF
definition:
Catalysis of the endohydrolysis of 1,4-alpha-D-glucosidic linkages in alpha-D-glucans containing both 1,3- and 1,4-bonds.


go_id: GO:0033912
term: 2,6-beta-fructan 6-levanbiohydrolase activity
ontology: MF
definition:
Catalysis of the hydrolysis of (2->6)-beta-D-fructofuranan, to remove successive disaccharide residues as levanbiose, i.e. 6-(beta-D-fructofuranosyl)-D-fructose, from the end of the chain.


go_id: GO:0033914
term: xylan 1,3-beta-xylosidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of successive xylose residues from the non-reducing termini of (1->3)-beta-D-xylans.


go_id: GO:0033916
term: beta-agarase activity
ontology: MF
definition:
Catalysis of the hydrolysis of (1->4)-beta-D-galactosidic linkages in agarose, giving the tetramer as the predominant product.


go_id: GO:0033918
term: kappa-carrageenase activity
ontology: MF
definition:
Catalysis of the endohydrolysis of 1,4-beta-D-linkages between D-galactose 4-sulfate and 3,6-anhydro-D-galactose in kappa-carrageenans.


go_id: GO:0033920
term: 6-phospho-beta-galactosidase activity
ontology: MF
definition:
Catalysis of the reaction: a 6-phospho-beta-D-galactoside + H2O = 6-phospho-D-galactose + an alcohol.


go_id: GO:0033921
term: capsular-polysaccharide endo-1,3-alpha-galactosidase activity
ontology: MF
definition:
Catalysis of the random hydrolysis of (1->3)-alpha-D-galactosidic linkages in Aerobacter aerogenes capsular polysaccharide.


go_id: GO:0033923
term: glucan 1,6-alpha-isomaltosidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in polysaccharides, to remove successive isomaltose units from the non-reducing ends of the chains.


go_id: GO:0033924
term: dextran 1,6-alpha-isomaltotriosidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in dextrans, to remove successive isomaltotriose units from the non-reducing ends of the chains.


go_id: GO:0033925
term: mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity
ontology: MF
definition:
Catalysis of the endohydrolysis of the N,N'-diacetylchitobiosyl unit in high-mannose glycopeptides and glycoproteins containing the -[Man(GlcNAc)2]Asn-structure. One N-acetyl-D-glucosamine residue remains attached to the protein; the rest of the oligosaccharide is released intact.


go_id: GO:0033926
term: glycopeptide alpha-N-acetylgalactosaminidase activity
ontology: MF
definition:
Catalysis of the reaction: D-galactosyl-3-(N-acetyl-alpha-D-galactosaminyl)-L-serine + H2O = D-galactosyl-3-N-acetyl-alpha-D-galactosamine + L-serine in mucin-type glycoproteins.


go_id: GO:0033927
term: glucan 1,4-alpha-maltohexaosidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltohexaose residues from the non-reducing chain ends.


go_id: GO:0033928
term: mannan 1,4-mannobiosidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of (1->4)-beta-D-mannosidic linkages in (1->4)-beta-D-mannans, to remove successive mannobiose residues from the non-reducing chain ends.


go_id: GO:0033929
term: blood-group-substance endo-1,4-beta-galactosidase activity
ontology: MF
definition:
Catalysis of the endohydrolysis of (1->4)-beta-D-galactosidic linkages in blood group A and B substances.


go_id: GO:0033931
term: endogalactosaminidase activity
ontology: MF
definition:
Catalysis of the endohydrolysis of (1->4)-alpha-D-galactosaminidic linkages in poly(D-galactosamine).


go_id: GO:0033932
term: 1,3-alpha-L-fucosidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of (1->3) linkages between alpha-L-fucose and N-acetylglucosamine residues in glycoproteins.


go_id: GO:0033933
term: branched-dextran exo-1,2-alpha-glucosidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of (1->2)-alpha-D-glucosidic linkages at the branch points of dextrans and related polysaccharides, producing free D-glucose.


go_id: GO:0033934
term: glucan 1,4-alpha-maltotriohydrolase activity
ontology: MF
definition:
Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltotriose residues from the non-reducing chain ends.


go_id: GO:0033935
term: oligoxyloglucan beta-glycosidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of (1->4)-beta-D-glucosidic links in oligoxyloglucans so as to remove successive isoprimeverose (i.e. alpha-xylo-1,6-beta-D-glucosyl-) residues from the non-reducing chain ends.


go_id: GO:0033937
term: 3-deoxy-2-octulosonidase activity
ontology: MF
definition:
Catalysis of the endohydrolysis of the beta-ketopyranosidic linkages of 3-deoxy-D-manno-2-octulosonate in capsular polysaccharides.


go_id: GO:0033938
term: 1,6-alpha-L-fucosidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of (1->6) linkages between alpha-L-fucose and N-acetyl-D-glucosamine in glycopeptides such as immunoglobulin G glycopeptide and fucosyl-asialo-agalacto-fetuin.


go_id: GO:0033939
term: xylan alpha-1,2-glucuronosidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of alpha-D-(1->2)-(4-O-methyl)glucuronosyl links in the main chain of hardwood xylans.


go_id: GO:0033941
term: mannan exo-1,2-1,6-alpha-mannosidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of (1->2)-alpha-D- and (1->6)-alpha-D- linkages in mannan, releasing D-mannose.


go_id: GO:0033942
term: 4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity
ontology: MF
definition:
Catalysis of the hydrolysis of alpha-(1->4)-D-glucosidic linkage in 4-alpha-D-{(1->4)-alpha-D-glucanosyl}n trehalose to yield trehalose and alpha-(1->4)-D-glucan.


go_id: GO:0033943
term: galactan 1,3-beta-galactosidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of terminal, non-reducing beta-D-galactose residues in (1->3)-beta-D-galactopyranans.


go_id: GO:0033944
term: beta-galactofuranosidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of terminal non-reducing beta-D-galactofuranosides, releasing galactose.


go_id: GO:0033945
term: oligoxyloglucan reducing-end-specific cellobiohydrolase activity
ontology: MF
definition:
Catalysis of the hydrolysis of cellobiose from the reducing end of xyloglucans consisting of a beta-(1->4) linked glucan carrying alpha-D-xylosyl groups on O-6 of the glucose residues. To be a substrate, the first residue must be unsubstituted, the second residue may bear a xylosyl group, whether further glycosylated or not, and the third residue, which becomes the new terminus by the action of the enzyme, is preferably xylosylated, but this xylose residue must not be further substituted.


go_id: GO:0033946
term: xyloglucan-specific endo-beta-1,4-glucanase activity
ontology: MF
definition:
Catalysis of the reaction: xyloglucan + H2O = xyloglucan oligosaccharides. This reaction is the endohydrolysis of (1->4)-beta-D-glucosidic linkages in xyloglucan.


go_id: GO:0033947
term: mannosylglycoprotein endo-beta-mannosidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of the alpha-D-mannosyl-(1->6)-beta-D-mannosyl-(1->4)-beta-D-N-acetylglucosaminyl-(1->4)-beta-D-N-acetylglucosaminyl sequence of glycoprotein to alpha-D-mannosyl-(1->6)-D-mannose and beta-D-N-acetylglucosaminyl-(1->4)-beta-D-N-acetylglucosaminyl sequences.


go_id: GO:0033948
term: fructan beta-(2,1)-fructosidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of terminal, non-reducing (2->1) linked beta-D-fructofuranose residues in fructans.


go_id: GO:0033949
term: fructan beta-(2,6)-fructosidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of terminal, non-reducing (2->6) linked beta-D-fructofuranose residues in fructans.


go_id: GO:0033950
term: xyloglucan-specific exo-beta-1,4-glucanase activity
ontology: MF
definition:
Catalysis of the reaction: xyloglucan + H2O = xyloglucan oligosaccharides. This reaction is the exohydrolysis of 1,4-beta-D-glucosidic linkages in xyloglucan.


go_id: GO:0033951
term: oligosaccharide reducing-end xylanase activity
ontology: MF
definition:
Catalysis of the hydrolysis of 1,4-beta-D-xylose residues from the reducing end of oligosaccharides.


go_id: GO:0033952
term: iota-carrageenase activity
ontology: MF
definition:
Catalysis of the endohydrolysis of 1,4-beta-D-linkages between D-galactose 4-sulfate and 3,6-anhydro-D-galactose-2-sulfate in iota-carrageenans.


go_id: GO:0033953
term: alpha-agarase activity
ontology: MF
definition:
Catalysis of the endohydrolysis of 1,3-alpha-L-galactosidic linkages in agarose, yielding agarotetraose as the major product.


go_id: GO:0033954
term: alpha-neoagaro-oligosaccharide hydrolase activity
ontology: MF
definition:
Catalysis of the hydrolysis of the 1,3-alpha-L-galactosidic linkages of neoagaro-oligosaccharides that are smaller than a hexamer, yielding 3,6-anhydro-L-galactose and D-galactose.


go_id: GO:0033956
term: beta-apiosyl-beta-glucosidase activity
ontology: MF
definition:
Catalysis of the reaction: 7-[beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranosyloxy]isoflavonoid + H2O = a 7-hydroxyisoflavonoid + beta-D-apiofuranosyl-(1->6)-D-glucose.


go_id: GO:0033957
term: lambda-carrageenase activity
ontology: MF
definition:
Catalysis of the endohydrolysis of beta-1,4-linkages in the backbone of lambda-carrageenan, resulting in the tetrasaccharide alpha-D-Galp2,6S2-(1->3)-beta-D-Galp2S-(1->4)-alpha-D-Galp2,6S2-(1->3)-D-Galp2S.


go_id: GO:0033959
term: deoxyribodipyrimidine endonucleosidase activity
ontology: MF
definition:
Catalysis of the cleavage of the N-glycosidic bond between the 5'-pyrimidine residue in cyclobutadipyrimidine (in DNA) and the corresponding deoxy-D-ribose residue.


go_id: GO:0033962
term: P-body assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body.


go_id: GO:0033963
term: cholesterol-5,6-oxide hydrolase activity
ontology: MF
definition:
Catalysis of the reactions: 5,6alpha-epoxy-5alpha-cholestan-3beta-ol + H2O = cholestane-3beta-5alpha,6beta-triol, and 5,6beta-epoxy-5beta-cholestan-3beta-ol + H2O = cholestane-3beta-5alpha,6beta-triol.


go_id: GO:0033964
term: glycosphingolipid deacylase activity
ontology: MF
definition:
Catalysis of the hydrolysis of gangliosides and neutral glycosphingolipids, releasing fatty acids to form the lyso-derivatives.


go_id: GO:0033965
term: aculeacin-A deacylase activity
ontology: MF
definition:
Catalysis of the hydrolysis of the amide bond in aculeacin A and related neutral lipopeptide antibiotics, releasing the long-chain fatty acid side-chain.


go_id: GO:0033968
term: glutaryl-7-aminocephalosporanic-acid acylase activity
ontology: MF
definition:
Catalysis of the reaction: (7R)-7-(4-carboxybutanamido)cephalosporanate + H2O = (7R)-7-aminocephalosporanate + glutarate.


go_id: GO:0033969
term: gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ontology: MF
definition:
Catalysis of the reaction: 4-(L-gamma-glutamylamino)butanoate + H(2)O = 4-aminobutanoate + L-glutamate.


go_id: GO:0033971
term: hydroxyisourate hydrolase activity
ontology: MF
definition:
Catalysis of the reaction: 5-hydroxyisourate + H(2)O = 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H(+).


go_id: GO:0033976
term: 2-haloacid dehalogenase (configuration-inverting) activity
ontology: MF
definition:
Catalysis of the reactions: (S)-2-haloacid + H2O = (R)-2-hydroxyacid + halide, and (R)-2-haloacid + H2O = (S)-2-hydroxyacid + halide.


go_id: GO:0033977
term: 2-haloacid dehalogenase (configuration-retaining) activity
ontology: MF
definition:
Catalysis of the reactions: (S)-2-haloacid + H2O = (S)-2-hydroxyacid + halide, and (R)-2-haloacid + H2O = (R)-2-hydroxyacid + halide.


go_id: GO:0033982
term: 3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ontology: MF
definition:
Catalysis of the reaction: 3-dehydro-L-gulonate 6-phosphate + H(+) = L-xylulose 5-phosphate + CO(2).


go_id: GO:0033984
term: indole-3-glycerol-phosphate lyase activity
ontology: MF
definition:
Catalysis of the reaction: (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate = indole + D-glyceraldehyde 3-phosphate.


go_id: GO:0033986
term: response to methanol
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methanol stimulus.


go_id: GO:0033988
term: bile-acid 7alpha-dehydratase activity
ontology: MF
definition:
Catalysis of the reaction: 7alpha,12alpha-dihydroxy-3-oxochol-4-en-24-oate = 12alpha-hydroxy-3-oxochola-4,6-dien-24-oate + H(2)O.


go_id: GO:0033989
term: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity
ontology: MF
definition:
Catalysis of the reaction: (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA = (24E)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA + H2O.


go_id: GO:0033991
term: aldos-2-ulose dehydratase activity
ontology: MF
definition:
Catalysis of the reactions: 1,5-anhydro-D-fructose = 2-hydroxy-2-(hydroxymethyl)-2H-pyran-3(6H)-one + H2O; (1a) 1,5-anhydro-D-fructose = 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose + H2O and (1b) 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose = 2-hydroxy-2-(hydroxymethyl)-2H-pyran-3(6H)-one.


go_id: GO:0033992
term: 1,5-anhydro-D-fructose dehydratase activity
ontology: MF
definition:
Catalysis of the reaction: 1,5-anhydro-D-fructose = 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose + H2O.


go_id: GO:0033993
term: response to lipid
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus.


go_id: GO:0033994
term: glucuronan lyase activity
ontology: MF
definition:
Catalysis of the reaction: (1->4)-beta-D-glucuronan = an oligosaccharide with 4-deoxy-beta-D-gluc-4-enuronosyl end + (1->4)-beta-D-glucuronan. This reaction is the eliminative cleavage of (1->4)-beta-D-glucuronans to give oligosaccharides with 4-deoxy-beta-D-gluc-4-enuronosyl groups at their non-reducing ends. Complete degradation of glucuronans results in the formation of tetrasaccharides.


go_id: GO:0033995
term: anhydrosialidase activity
ontology: MF
definition:
Catalysis of the reaction: an N-acetylneuraminate glycoside = 2,7-anhydro-alpha-N-acetylneuraminate + an alpha-sialyl group. This reaction is the elimination of alpha-sialyl groups in N-acetylneuraminic acid glycosides, releasing 2,7-anhydro-alpha-N-acetylneuraminate.


go_id: GO:0033996
term: levan fructotransferase (DFA-IV-forming) activity
ontology: MF
definition:
Catalysis of the reaction: beta-D-fructopyranosyl-(2->6)-[D-fructofuranosyl-(2->6)]n-D-fructofuranoside = beta-D-fructopyranosyl-(2->6)-[D-fructofuranosyl-(2->6)](n-1)-D-fructofuranoside + di-beta-D-fructofuranose 2,6':2',6-dianhydride. This reaction is the production of di-beta-D-fructofuranose 2,6':2',6-dianhydride (DFA IV) by successively eliminating the diminishing (2->6)-beta-D-fructan (levan) chain from the terminal D-fructosyl-D-fructosyl disaccharide.


go_id: GO:0033997
term: inulin fructotransferase (DFA-I-forming) activity
ontology: MF
definition:
Catalysis of the reaction: [(2->1)-beta-D-fructosyl](n) = [(2->1)-beta-D-fructosyl](n-1) + alpha-D-fructofuranose-beta-D-fructofuranose 1,2':1,2'-dianhydride. This reaction is the production of alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,1'-dianhydride (DFA I) by successively eliminating the diminishing (2->1)-beta-D-fructan (inulin) chain from the terminal D-fructosyl-D-fructosyl disaccharide.


go_id: GO:0033998
term: inulin fructotransferase (DFA-III-forming) activity
ontology: MF
definition:
Catalysis of the reaction: [(2->1)-beta-D-fructosyl](n) = [(2->1)-beta-D-fructosyl](n-1) + alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,3'-dianhydride. This reaction is the production of alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,3'-dianhydride (DFA III) by successively eliminating the diminishing (2->1)-beta-D-fructan (inulin) chain from the terminal D-fructosyl-D-fructosyl disaccharide.


go_id: GO:0033999
term: chondroitin B lyase activity
ontology: MF
definition:
Catalysis of the reaction: dermatan sulfate = n 4-deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 4-sulfate. This reaction is the eliminative cleavage of dermatan sulfate containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucurosonyl or 1,3-alpha-L-iduronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups to yield a 4,5-unsaturated dermatan-sulfate disaccharide (DeltaUA-GalNAC-4S). Chondroitin sulfate B is also known as dermatan sulfate.


go_id: GO:0034000
term: chondroitin-sulfate-ABC endolyase activity
ontology: MF
definition:
Catalysis of the endolytic cleavage of beta-1,4-galactosaminic bonds between N-acetylgalactosamine and either D-glucuronic acid or L-iduronic acid to produce a mixture of Delta4-unsaturated oligosaccharides of different sizes that are ultimately degraded to Delta4-unsaturated tetra- and disaccharides.


go_id: GO:0034001
term: chondroitin-sulfate-ABC exolyase activity
ontology: MF
definition:
Catalysis of the exolytic cleavage of disaccharide residues from the non-reducing ends of both polymeric chondroitin sulfates and their oligosaccharide fragments.


go_id: GO:0034004
term: germacradienol synthase activity
ontology: MF
definition:
Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + H2O = (1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + diphosphate.


go_id: GO:0034005
term: germacrene-A synthase activity
ontology: MF
definition:
Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (+)-(R)-germacrene A + diphosphate.


go_id: GO:0034014
term: response to triglyceride
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triglyceride stimulus.


go_id: GO:0034016
term: polyenoic fatty acid isomerase activity
ontology: MF
definition:
Catalysis of the reaction: all-cis-icosa-5,8,11,14,17-pentaenoate = (5Z,7E,9E,14Z,17Z)-icosapentaenoate.


go_id: GO:0034017
term: trans-2-decenoyl-acyl-carrier-protein isomerase activity
ontology: MF
definition:
Catalysis of the reaction: trans-dec-2-enoyl-[acyl-carrier protein] = cis-dec-3-enoyl-[acyl-carrier protein].


go_id: GO:0034018
term: ascopyrone tautomerase activity
ontology: MF
definition:
Catalysis of the reaction: 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose = 1,5-anhydro-4-deoxy-D-glycero-hex-1-en-3-ulose.


go_id: GO:0034021
term: response to silicon dioxide
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silicon dioxide stimulus.


go_id: GO:0034023
term: 5-(carboxyamino)imidazole ribonucleotide mutase activity
ontology: MF
definition:
Catalysis of the reaction: 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate.


go_id: GO:0034024
term: glutamate-putrescine ligase activity
ontology: MF
definition:
Catalysis of the reaction: L-glutamate + ATP + putrescine = gamma-L-glutamylputrescine + ADP + 2 H(+) + phosphate.


go_id: GO:0034025
term: D-aspartate ligase activity
ontology: MF
definition:
Catalysis of the reaction: ATP + D-aspartate + [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n = [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-6-N-(beta-D-Asp)-L-Lys-D-Ala-D-Ala)]n + ADP + phosphate.


go_id: GO:0034026
term: L-amino-acid alpha-ligase activity
ontology: MF
definition:
Catalysis of the reaction: ATP + an L-amino acid + an L-amino acid = ADP + phosphate + L-aminoacyl-L-amino acid.


go_id: GO:0034027
term: (carboxyethyl)arginine beta-lactam-synthase activity
ontology: MF
definition:
Catalysis of the reaction: N(2)-(2-carboxyethyl)-L-arginine + ATP = AMP + deoxyamidinoproclavaminate + diphosphate + 2 H(+).


go_id: GO:0034028
term: 5-(carboxyamino)imidazole ribonucleotide synthase activity
ontology: MF
definition:
Catalysis of the reaction: 5-amino-1-(5-phospho-D-ribosyl)imidazole + ATP + bicarbonate = 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + ADP + 3 H(+) + phosphate.


go_id: GO:0034029
term: 2-oxoglutarate carboxylase activity
ontology: MF
definition:
Catalysis of the reaction: 2-oxoglutarate + ATP + bicarbonate = ADP + 2 H(+) + oxalosuccinate + phosphate.


go_id: GO:0034030
term: ribonucleoside bisphosphate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a ribonucleoside bisphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.


go_id: GO:0034031
term: ribonucleoside bisphosphate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of a ribonucleoside bisphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.


go_id: GO:0034032
term: purine nucleoside bisphosphate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving a purine nucleoside bisphosphate, a compound consisting of a purine base linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.


go_id: GO:0034033
term: purine nucleoside bisphosphate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a purine nucleoside bisphosphate, a compound consisting of a purine base linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.


go_id: GO:0034034
term: purine nucleoside bisphosphate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of a purine nucleoside bisphosphate, a compound consisting of a purine base linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.


go_id: GO:0034035
term: purine ribonucleoside bisphosphate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving a purine ribonucleoside bisphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.


go_id: GO:0034036
term: purine ribonucleoside bisphosphate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a purine ribonucleoside bisphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.


go_id: GO:0034037
term: purine ribonucleoside bisphosphate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of a purine ribonucleoside bisphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.


go_id: GO:0034038
term: deoxyhypusine synthase activity
ontology: MF
definition:
Catalysis of the reaction: [eIF5A-precursor]-lysine + spermidine = [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine. Four sub-reactions have been identified,in which the intermediates remain tightly associated with the enzyme: spermidine + NAD+ = dehydrospermidine + NADH; dehydrospermidine + [enzyme]-lysine = N-(4-aminobutylidene)-[enzyme]-lysine + propane-1,3-diamine; N-(4-aminobutylidene)-[enzyme]-lysine + [eIF5A-precursor]-lysine = N-(4-aminobutylidene)-[eIF5A-precursor]-lysine + [enzyme]-lysine; N-(4-aminobutylidene)-[eIF5A-precursor]-lysine + NADH + H+ = [eIF5A-precursor]-deoxyhypusine + NAD+.


go_id: GO:0034039
term: 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity
ontology: MF
definition:
Catalysis of the removal of 8-oxo-7,8-dihydroguanine bases by cleaving the N-C1' glycosidic bond between the oxidized purine and the deoxyribose sugar.


go_id: GO:0034040
term: ATPase-coupled lipid transmembrane transporter activity
ontology: MF
definition:
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + lipid(in) = ADP + phosphate + lipid(out).


go_id: GO:0034041
term: ABC-type sterol transporter activity
ontology: MF
definition:
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + sterol(in) = ADP + phosphate + sterol(out).


go_id: GO:0034042
term: 5-formyluracil DNA N-glycosylase activity
ontology: MF
definition:
Catalysis of the removal of 5-formyluracil bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar.


go_id: GO:0034043
term: 5-hydroxymethyluracil DNA N-glycosylase activity
ontology: MF
definition:
Catalysis of the removal of 5-hydroxymethyluracil bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar.


go_id: GO:0034044
term: exomer complex
ontology: CC
definition:
A protein complex that forms a coat structure on vesicles involved in exocytosis of proteins from the trans-Golgi network to the cell surface; in Saccharomyces, the complex contains Chs5p, Chs6p, and Chs6p paralogues.


go_id: GO:0034050
term: programmed cell death induced by symbiont
ontology: BP
definition:
Cell death resulting from activation of endogenous cellular processes after interaction with a symbiont (defined as the smaller of two, or more, organisms engaged in symbiosis, a close interaction encompassing mutualism through parasitism). This can be triggered by direct interaction with the organism, for example, contact with penetrating hyphae of a fungus; or an indirect interaction such as symbiont-secreted molecules.


go_id: GO:0034051
term: negative regulation of plant-type hypersensitive response
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the hypersensitive response in a plant.


go_id: GO:0034052
term: positive regulation of plant-type hypersensitive response
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the hypersensitive response in a plant.


go_id: GO:0034053
term: modulation by symbiont of host defense-related programmed cell death
ontology: BP
definition:
Any process in which a symbiont modulates the frequency, rate or extent of defense-related programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0034054
term: suppression by symbiont of host defense-related programmed cell death
ontology: BP
definition:
Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of defense-related programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0034055
term: effector-mediated induction of programmed cell death in host
ontology: BP
definition:
A symbiont process in which a molecule secreted by the symbiont activates a programmed cell death pathway in the host to suppress the host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0034056
term: estrogen response element binding
ontology: MF
definition:
Binding to an estrogen response element (ERE), a conserved sequence found in the promoters of genes whose expression is regulated in response to estrogen.


go_id: GO:0034057
term: RNA strand-exchange activity
ontology: MF
definition:
Facilitates the displacement of one strand of an RNA-RNA duplex and its replacement with a different strand of higher complementarity.


go_id: GO:0034059
term: response to anoxia
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating a decline in oxygen levels to trace amounts, <0.1%.


go_id: GO:0034061
term: DNA polymerase activity
ontology: MF
definition:
Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a nucleic acid template and a 3'hydroxyl group.


go_id: GO:0034062
term: 5'-3' RNA polymerase activity
ontology: MF
definition:
Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template, via extension of the 3'-end.


go_id: GO:0034063
term: stress granule assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule.


go_id: GO:0034064
term: Tor2-Mei2-Ste11 complex
ontology: CC
definition:
A protein complex that contains the transcription factor Ste11 and the RNA binding protein Mei2; involved in regulation of conjugation in fission yeast.


go_id: GO:0034066
term: Ric1-Rgp1 guanyl-nucleotide exchange factor complex
ontology: CC
definition:
A protein complex that acts as a nucleotide exchange factor for the GTPase Ypt6p, and is required for fusion of endosome-derived vesicles with the Golgi.


go_id: GO:0034067
term: protein localization to Golgi apparatus
ontology: BP
definition:
A process in which a protein is transported to, or maintained in, a location within the Golgi apparatus.


go_id: GO:0034068
term: aminoglycoside nucleotidyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: nucleoside triphosphate + aminoglycoside = diphosphate + nucleotidylaminoglycoside.


go_id: GO:0034070
term: aminoglycoside 1-N-acetyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + 1-N-acetylaminoglycoside. This is acetylation of the 1-amino group of the central deoxystreptamine ring.


go_id: GO:0034075
term: arabidiol synthase activity
ontology: MF
definition:
Catalysis of the reaction: oxidosqualene + H2O = arabidiol ((13R,14R,17E)-malabarica-17,21-diene-3beta,14-diol).


go_id: GO:0034077
term: butanediol metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3.


go_id: GO:0034078
term: butanediol catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3.


go_id: GO:0034079
term: butanediol biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3.


go_id: GO:0034080
term: CENP-A containing chromatin assembly
ontology: BP
definition:
The formation of chromatin containing the histone H3 variant CENP-A to form centromeric chromatin. This specialised chromatin occurs at centromeric region in point centromeres,  and the central core in modular centromeres.


go_id: GO:0034081
term: polyketide synthase complex
ontology: CC
definition:
A protein complex that carries out enzymatic reactions involved in the biosynthesis of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones.


go_id: GO:0034082
term: type II polyketide synthase complex
ontology: CC
definition:
A polyketide synthase complex that consists of several different polypeptide chains, each of which catalyzes a single reaction.


go_id: GO:0034085
term: establishment of sister chromatid cohesion
ontology: BP
definition:
The process in which the sister chromatids of a replicated chromosome become associated with each other during S phase.


go_id: GO:0034086
term: maintenance of sister chromatid cohesion
ontology: BP
definition:
The process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate.


go_id: GO:0034087
term: establishment of mitotic sister chromatid cohesion
ontology: BP
definition:
The process in which the sister chromatids of a replicated chromosome become joined along the entire length of the chromosome during S phase during a mitotic cell cycle.


go_id: GO:0034088
term: maintenance of mitotic sister chromatid cohesion
ontology: BP
definition:
The process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle.


go_id: GO:0034089
term: establishment of meiotic sister chromatid cohesion
ontology: BP
definition:
The process in which the sister chromatids of a replicated chromosome become joined along the entire length of the chromosome during S phase during a meiotic cell cycle.


go_id: GO:0034090
term: maintenance of meiotic sister chromatid cohesion
ontology: BP
definition:
The process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a meiotic cell cycle.


go_id: GO:0034091
term: regulation of maintenance of sister chromatid cohesion
ontology: BP
definition:
Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained.


go_id: GO:0034092
term: negative regulation of maintenance of sister chromatid cohesion
ontology: BP
definition:
Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained.


go_id: GO:0034093
term: positive regulation of maintenance of sister chromatid cohesion
ontology: BP
definition:
Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained.


go_id: GO:0034094
term: regulation of maintenance of meiotic sister chromatid cohesion
ontology: BP
definition:
Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle.


go_id: GO:0034095
term: negative regulation of maintenance of meiotic sister chromatid cohesion
ontology: BP
definition:
Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle.


go_id: GO:0034096
term: positive regulation of maintenance of meiotic sister chromatid cohesion
ontology: BP
definition:
Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle.


go_id: GO:0034097
term: response to cytokine
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.


go_id: GO:0034098
term: VCP-NPL4-UFD1 AAA ATPase complex
ontology: CC
definition:
A multiprotein ATPase complex required for the efficient dislocation of ER-lumenal degradation substrates, and their subsequent proteolysis by the proteasome. In budding yeast, this complex includes Cdc48p, Npl4p and Ufd1p proteins. In mammals, this complex includes a hexamer of VCP/p97 (a cytosolic ATPase) and trimers of each of its cofactors UFD1L and NPL4 (NPLOC4) (e.g. a 6:3:3 stoichiometry).


go_id: GO:0034099
term: luminal surveillance complex
ontology: CC
definition:
A multiprotein complex that recognizes ERAD-luminal misfolded substrates and brings them to the ubiquitination/extraction machinery. In yeast, this complex consists of Yos9p, Kar2p and Hrd3p proteins.


go_id: GO:0034107
term: negative regulation of erythrocyte clearance
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of erythrocyte clearance.


go_id: GO:0034111
term: negative regulation of homotypic cell-cell adhesion
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of homotypic cell-cell adhesion.


go_id: GO:0034112
term: positive regulation of homotypic cell-cell adhesion
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of homotypic cell-cell adhesion.


go_id: GO:0034115
term: negative regulation of heterotypic cell-cell adhesion
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of heterotypic cell-cell adhesion.


go_id: GO:0034116
term: positive regulation of heterotypic cell-cell adhesion
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of heterotypic cell-cell adhesion.


go_id: GO:0034119
term: negative regulation of erythrocyte aggregation
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of erythrocyte aggregation.


go_id: GO:0034122
term: negative regulation of toll-like receptor signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor signaling pathway.


go_id: GO:0034123
term: positive regulation of toll-like receptor signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of toll-like receptor signaling pathway.


go_id: GO:0034124
term: regulation of MyD88-dependent toll-like receptor signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway.


go_id: GO:0034125
term: negative regulation of MyD88-dependent toll-like receptor signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway.


go_id: GO:0034126
term: positive regulation of MyD88-dependent toll-like receptor signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway.


go_id: GO:0034127
term: regulation of MyD88-independent toll-like receptor signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway.


go_id: GO:0034128
term: negative regulation of MyD88-independent toll-like receptor signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway.


go_id: GO:0034129
term: positive regulation of MyD88-independent toll-like receptor signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway.


go_id: GO:0034131
term: regulation of toll-like receptor 1 signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of toll-like receptor 1 signaling pathway.


go_id: GO:0034132
term: negative regulation of toll-like receptor 1 signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 1 signaling pathway.


go_id: GO:0034133
term: positive regulation of toll-like receptor 1 signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 1 signaling pathway.


go_id: GO:0034135
term: regulation of toll-like receptor 2 signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of toll-like receptor 2 signaling pathway.


go_id: GO:0034136
term: negative regulation of toll-like receptor 2 signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 2 signaling pathway.


go_id: GO:0034137
term: positive regulation of toll-like receptor 2 signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 2 signaling pathway.


go_id: GO:0034139
term: regulation of toll-like receptor 3 signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of toll-like receptor 3 signaling pathway.


go_id: GO:0034140
term: negative regulation of toll-like receptor 3 signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 3 signaling pathway.


go_id: GO:0034141
term: positive regulation of toll-like receptor 3 signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 3 signaling pathway.


go_id: GO:0034143
term: regulation of toll-like receptor 4 signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of toll-like receptor 4 signaling pathway.


go_id: GO:0034144
term: negative regulation of toll-like receptor 4 signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 4 signaling pathway.


go_id: GO:0034145
term: positive regulation of toll-like receptor 4 signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 4 signaling pathway.


go_id: GO:0034147
term: regulation of toll-like receptor 5 signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of toll-like receptor 5 signaling pathway.


go_id: GO:0034148
term: negative regulation of toll-like receptor 5 signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 5 signaling pathway.


go_id: GO:0034149
term: positive regulation of toll-like receptor 5 signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 5 signaling pathway.


go_id: GO:0034151
term: regulation of toll-like receptor 6 signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of toll-like receptor 6 signaling pathway.


go_id: GO:0034152
term: negative regulation of toll-like receptor 6 signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 6 signaling pathway.


go_id: GO:0034153
term: positive regulation of toll-like receptor 6 signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 6 signaling pathway.


go_id: GO:0034155
term: regulation of toll-like receptor 7 signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of toll-like receptor 7 signaling pathway.


go_id: GO:0034156
term: negative regulation of toll-like receptor 7 signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 7 signaling pathway.


go_id: GO:0034157
term: positive regulation of toll-like receptor 7 signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 7 signaling pathway.


go_id: GO:0034159
term: regulation of toll-like receptor 8 signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of toll-like receptor 8 signaling pathway.


go_id: GO:0034160
term: negative regulation of toll-like receptor 8 signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 8 signaling pathway.


go_id: GO:0034161
term: positive regulation of toll-like receptor 8 signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 8 signaling pathway.


go_id: GO:0034163
term: regulation of toll-like receptor 9 signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of toll-like receptor 9 signaling pathway.


go_id: GO:0034164
term: negative regulation of toll-like receptor 9 signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 9 signaling pathway.


go_id: GO:0034165
term: positive regulation of toll-like receptor 9 signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 9 signaling pathway.


go_id: GO:0034167
term: regulation of toll-like receptor 10 signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of toll-like receptor 10 signaling pathway.


go_id: GO:0034168
term: negative regulation of toll-like receptor 10 signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 10 signaling pathway.


go_id: GO:0034169
term: positive regulation of toll-like receptor 10 signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 10 signaling pathway.


go_id: GO:0034171
term: regulation of toll-like receptor 11 signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of toll-like receptor 11 signaling pathway.


go_id: GO:0034172
term: negative regulation of toll-like receptor 11 signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 11 signaling pathway.


go_id: GO:0034173
term: positive regulation of toll-like receptor 11 signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 11 signaling pathway.


go_id: GO:0034175
term: regulation of toll-like receptor 12 signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of toll-like receptor 12 signaling pathway.


go_id: GO:0034176
term: negative regulation of toll-like receptor 12 signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 12 signaling pathway.


go_id: GO:0034177
term: positive regulation of toll-like receptor 12 signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 12 signaling pathway.


go_id: GO:0034179
term: regulation of toll-like receptor 13 signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of toll-like receptor 13 signaling pathway.


go_id: GO:0034180
term: negative regulation of toll-like receptor 13 signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 13 signaling pathway.


go_id: GO:0034181
term: positive regulation of toll-like receptor 13 signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 13 signaling pathway.


go_id: GO:0034182
term: regulation of maintenance of mitotic sister chromatid cohesion
ontology: BP
definition:
Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle.


go_id: GO:0034183
term: negative regulation of maintenance of mitotic sister chromatid cohesion
ontology: BP
definition:
Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle.


go_id: GO:0034184
term: positive regulation of maintenance of mitotic sister chromatid cohesion
ontology: BP
definition:
Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle.


go_id: GO:0034188
term: apolipoprotein A-I receptor activity
ontology: MF
definition:
Combining with an apolipoprotein A-I receptor ligand and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


go_id: GO:0034189
term: very-low-density lipoprotein particle binding
ontology: MF
definition:
Binding to a very-low-density lipoprotein particle, a triglyceride-rich lipoprotein particle that is typically composed of APOB100, APOE and APOCs and has a density of about 1.006 g/ml and a diameter of between 20-80 nm.


go_id: GO:0034194
term: D-galactonate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of D-galactonate, the anion of D-galactonic acid.


go_id: GO:0034195
term: L-galactonate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of L-galactonate, the anion of L-galactonic acid.


go_id: GO:0034196
term: acylglycerol transport
ontology: BP
definition:
The directed movement of an acylglycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. An acylglycerol is any mono-, di- or triester of glycerol with (one or more) fatty acids.


go_id: GO:0034197
term: triglyceride transport
ontology: BP
definition:
The directed movement of triglyceride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Triglycerides are important components of plant oils, animal fats and animal plasma lipoproteins.


go_id: GO:0034198
term: cellular response to amino acid starvation
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of amino acids.


go_id: GO:0034200
term: D,D-heptose 1,7-bisphosphate phosphatase activity
ontology: MF
definition:
Catalysis of the reaction: D-beta-D-heptose 1,7-bisphosphate + H2O = D-beta-D-heptose 1-phosphate + phosphate.


go_id: GO:0034201
term: response to oleic acid
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oleic acid stimulus.


go_id: GO:0034202
term: glycolipid floppase activity
ontology: MF
definition:
Catalysis of the movement of a glycolipid from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP.


go_id: GO:0034203
term: glycolipid translocation
ontology: BP
definition:
The translocation, or flipping, of glycolipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.


go_id: GO:0034204
term: lipid translocation
ontology: BP
definition:
The translocation, or flipping, of lipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.


go_id: GO:0034206
term: enhanceosome
ontology: CC
definition:
A protein-DNA complex formed by the association of a distinct set of general and specific transcription factors with a region of enhancer DNA. The cooperative assembly of an enhanceosome confers specificity of transcriptional regulation.


go_id: GO:0034207
term: steroid acetylation
ontology: BP
definition:
The addition of an acetyl group to a steroid molecule. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.


go_id: GO:0034208
term: steroid deacetylation
ontology: BP
definition:
The removal of an acetyl group from a steroid molecule. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.


go_id: GO:0034209
term: sterol acetylation
ontology: BP
definition:
The addition of an acetyl group to a sterol molecule. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.


go_id: GO:0034210
term: sterol deacetylation
ontology: BP
definition:
The removal of an acetyl group from a sterol molecule. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.


go_id: GO:0034211
term: GTP-dependent protein kinase activity
ontology: MF
definition:
GTP dependent catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate.


go_id: GO:0034212
term: peptide N-acetyltransferase activity
ontology: MF
definition:
Catalysis of the acetylation of an amino acid residue of a peptide or protein, according to the reaction: acetyl-CoA + peptide = CoA + N-acetylpeptide.


go_id: GO:0034213
term: quinolinate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid.


go_id: GO:0034214
term: protein hexamerization
ontology: BP
definition:
The formation of a protein hexamer, a macromolecular structure consisting of six noncovalently associated identical or nonidentical subunits.


go_id: GO:0034215
term: thiamine:proton symporter activity
ontology: MF
definition:
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: thiamine(out) + H+(out) = thiamine(in) + H+(in).


go_id: GO:0034216
term: high-affinity thiamine:proton symporter activity
ontology: MF
definition:
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: thiamine(out) + H+(out) = thiamine(in) + H+(in). In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.


go_id: GO:0034217
term: ascospore wall chitin biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of ascospore wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of ascospores.


go_id: GO:0034218
term: ascospore wall chitin metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving ascospore wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of ascospores.


go_id: GO:0034221
term: fungal-type cell wall chitin biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of cell wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of fungal cells.


go_id: GO:0034222
term: regulation of cell wall chitin metabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chitin in a cell wall.


go_id: GO:0034223
term: regulation of ascospore wall chitin biosynthetic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ascospore wall chitin.


go_id: GO:0034224
term: cellular response to zinc ion starvation
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of zinc ions.


go_id: GO:0034228
term: ethanolamine transmembrane transporter activity
ontology: MF
definition:
Enables the transfer of ethanolamine from one side of a membrane to the other. Ethanolamine (2-aminoethanol, monoethanolamine) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids, such as phosphatidylethanolamine.


go_id: GO:0034229
term: ethanolamine transport
ontology: BP
definition:
The directed movement of ethanolamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ethanolamine (2-aminoethanol, monoethanolamine) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids, such as phosphatidylethanolamine.


go_id: GO:0034230
term: enkephalin processing
ontology: BP
definition:
The formation of mature enkephalin, a pentapeptide hormone involved in regulating pain and nociception in the body by proteolytic processing of enkephalin propeptide.


go_id: GO:0034231
term: islet amyloid polypeptide processing
ontology: BP
definition:
The formation of mature islet amyloid polypeptide (IAPP) by posttranslational processing of pro-islet amyloid polypeptide (pro-IAPP).


go_id: GO:0034232
term: ascospore wall chitin catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of ascospore wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of ascospores.


go_id: GO:0034233
term: regulation of cell wall chitin catabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cell wall chitin.


go_id: GO:0034234
term: regulation of ascospore wall chitin catabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of ascospore wall chitin.


go_id: GO:0034235
term: GPI anchor binding
ontology: MF
definition:
Binding to a glycosylphosphatidylinositol anchor. GPI anchors serve to attach membrane proteins to the lipid bilayer of cell membranes.


go_id: GO:0034242
term: negative regulation of syncytium formation by plasma membrane fusion
ontology: BP
definition:
Any process that decreases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.


go_id: GO:0034243
term: regulation of transcription elongation by RNA polymerase II
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.


go_id: GO:0034244
term: negative regulation of transcription elongation by RNA polymerase II
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.


go_id: GO:0034245
term: mitochondrial DNA-directed RNA polymerase complex
ontology: CC
definition:
A DNA-directed RNA polymerase complex located in the mitochondrion. Mitochondrial RNA polymerase is composed of two subunits, a catalytic core, which resembles the enzymes from bacteriophage T7 and T3, and a specificity factor required for promoter recognition, which is similar to members of the eubacterial sigma factor family. In S. cerevisiae, these are encoded by the nuclear genes RPO41 and MTF1 and the specificity factor, required for promoter recognition and initiation, is not present in the elongating form.


go_id: GO:0034246
term: mitochondrial transcription factor activity
ontology: MF
definition:
Interacting with the mitochondrial promoter DNA to modulate transcription by the mitochondrial RNA polymerase.


go_id: GO:0034247
term: snoRNA splicing
ontology: BP
definition:
The process of removing sections of a primary snoRNA transcript to remove sequences not present in the mature form of the snoRNA and joining the remaining sections to form the mature form of the snoRNA.


go_id: GO:0034248
term: regulation of cellular amide metabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amides.


go_id: GO:0034249
term: negative regulation of cellular amide metabolic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amides.


go_id: GO:0034250
term: positive regulation of cellular amide metabolic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amides.


go_id: GO:0034251
term: regulation of cellular amide catabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides.


go_id: GO:0034252
term: negative regulation of cellular amide catabolic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides.


go_id: GO:0034253
term: positive regulation of cellular amide catabolic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides.


go_id: GO:0034254
term: regulation of urea catabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of urea.


go_id: GO:0034255
term: regulation of urea metabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving urea.


go_id: GO:0034256
term: chlorophyll(ide) b reductase activity
ontology: MF
definition:
Catalysis of the reaction: 71-hydroxychlorophyll(ide) a + NAD(P)+ = chlorophyll(ide) b + NAD(P)H + H+.


go_id: GO:0034257
term: nicotinamide riboside transmembrane transporter activity
ontology: MF
definition:
Enables the transfer of nicotinamide riboside, which is a pyridine-3-carboxamide covalently bonded to a ribose sugar, from one side of a membrane to the other.


go_id: GO:0034258
term: nicotinamide riboside transport
ontology: BP
definition:
The directed movement of a nicotinamide riboside, which is a pyridine-3-carboxamide covalently bonded to a ribose sugar, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0034263
term: positive regulation of autophagy in response to ER overload
ontology: BP
definition:
The process in which the accumulation of misfolded proteins in the endoplasmic reticulum triggers a response that positively regulates autophagy.


go_id: GO:0034265
term: isopentenyl adenine biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of the cytokinin 6-isopentenyladenine.


go_id: GO:0034266
term: isopentenyl adenine catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of the cytokinin 6-isopentenyladenine.


go_id: GO:0034267
term: discadenine metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving discadenine, (2S)-2-amino-4-{6-[(3-methylbut-2-en-1-yl)amino]-3H-purin-3-yl}butanoic acid.


go_id: GO:0034268
term: discadenine biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of discadenine, (2S)-2-amino-4-{6-[(3-methylbut-2-en-1-yl)amino]-3H-purin-3-yl}butanoic acid.


go_id: GO:0034269
term: discadenine catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of discadenine, (2S)-2-amino-4-{6-[(3-methylbut-2-en-1-yl)amino]-3H-purin-3-yl}butanoic acid.


go_id: GO:0034270
term: Cvt complex
ontology: CC
definition:
A protein complex that is involved in the Cvt pathway. In budding yeast, the Cvt complex consists of multimers of preApe1p.


go_id: GO:0034271
term: phosphatidylinositol 3-kinase complex, class III, type I
ontology: CC
definition:
A class III phosphatidylinositol 3-kinase complex that is involved in autophagy. In budding yeast, this complex consists of Vps30p, Vps34p, Apg14p and Vps15p.


go_id: GO:0034272
term: phosphatidylinositol 3-kinase complex, class III, type II
ontology: CC
definition:
A class III phosphatidylinositol 3-kinase complex that is involved in vacuolar protein sorting (VPS) via endosomes. In budding yeast, this complex consists of Vps30p, Vps34p, Vps38 and Vps15p.


go_id: GO:0034274
term: Atg12-Atg5-Atg16 complex
ontology: CC
definition:
A protein complex required for the expansion of the autophagosomal membrane. In budding yeast, this complex consists of Atg12p, Atg5p and Atg16p.


go_id: GO:0034276
term: kynurenic acid biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of kynurenic acid, 4-hydroxyquinoline-2-carboxylic acid.


go_id: GO:0034280
term: ent-sandaracopimaradiene synthase activity
ontology: MF
definition:
Catalysis of the reaction: ent-copalyl diphosphate = ent-sandaracopimara-8(14),15-diene + diphosphate.


go_id: GO:0034284
term: response to monosaccharide
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus.


go_id: GO:0034285
term: response to disaccharide
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disaccharide stimulus.


go_id: GO:0034286
term: response to maltose
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a maltose stimulus.


go_id: GO:0034287
term: detection of monosaccharide stimulus
ontology: BP
definition:
The series of events in which a stimulus from a monosaccharide is received and converted into a molecular signal.


go_id: GO:0034288
term: detection of disaccharide stimulus
ontology: BP
definition:
The series of events in which a stimulus from a disaccharide is received and converted into a molecular signal.


go_id: GO:0034289
term: detection of maltose stimulus
ontology: BP
definition:
The series of events in which a maltose stimulus is received by a cell and converted into a molecular signal.


go_id: GO:0034290
term: holin activity
ontology: MF
definition:
A compound function consisting of the regulated formation of a pore via oligomerisation of an existing pool of subunits in the plasma membrane.  The resulting channel activity directly or indirectly allows murein hydrolyases to access their cell wall substrate.


go_id: GO:0034291
term: canonical holin activity
ontology: MF
definition:
A compound function consisting of the regulated formation of a pore via oligomerisation of an existing pool of subunits in the plasma membrane.  The resulting channel activity directly allows release of a fully-folded phage-encoded endolysin (murein-degradase) from the cell.


go_id: GO:0034292
term: pinholin activity
ontology: MF
definition:
A compound function consisting of the regulated formation of a pore via oligomerisation of an existing pool of subunits in the plasma membrane.  The resulting ion channel activity indirectly allows endolysin (murein hydrolyases) to access their cell wall substrate by collapsing the proton motive force (PMF) across the membrane, allowing the endolysin to fold to an active form and hydrolyze bonds in the peptidoglycan cell wall.


go_id: GO:0034294
term: sexual spore wall assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form a sexual spore wall, the specialized envelope lying outside the cell membrane of a spore derived from a product of meiosis.


go_id: GO:0034295
term: basidiospore formation
ontology: BP
definition:
The process in which spores form outside a specialized end cell known as a basidium. Basidia are characteristic of the basidiomycete fungi (phylum Basidiomycota), and give rise to spores that each contain a haploid nucleus that is the product of meiosis. The spores are usually attached to the basidium by short spikes called sterigmata (singular: sterigma). In most basidiomycetes there are four sterigmata (and four spores) to a basidium.


go_id: GO:0034296
term: zygospore formation
ontology: BP
definition:
The process in which zygospores are formed. Zygospores are characteristic of the zygomycete fungi (phylum Zygomycota) thick-walled and darkly colored, and usually heavily ornamented as well, with many spines or ridges. It is formed between two specialized organs called suspensors, which are themselves usually heavily ornamented, one from each mating partner. The zygospore forms between them and then breaks away.


go_id: GO:0034297
term: oidium formation
ontology: BP
definition:
The process in which oidia, a type of asexual spore found in fungi, are formed. Oidia are borne a few at a time on very simple hyphae that protrude a short distance into the substrate, and are usually presumed not to constitute the main reproductive strategy of the fungus.


go_id: GO:0034298
term: arthrospore formation
ontology: BP
definition:
The formation of conidia by the conversion of a pre-existing hypha. An arthrospore is produced by the last cell on a hypha breaking off and dispersing. Usually the walls thicken and the cell(s) separates before swelling of each spore. Sometimes further septa form in each cell prior to disarticulation.


go_id: GO:0034299
term: reproductive blastospore formation
ontology: BP
definition:
The formation of a spore following the marked enlargement of part of a cell before separation by a septum. Blastospores are a type of asexual spore found in some fungi, most notably the class Glomeromycota.


go_id: GO:0034300
term: sporangiospore formation
ontology: BP
definition:
The process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm.


go_id: GO:0034301
term: endospore formation
ontology: BP
definition:
The process in which a cell gives rise to an endospore, a dormant, highly resistant spore with a thick wall that forms within the mother cell. Endospores are produced by some low G+C Gram-positive bacteria in response to harsh conditions.


go_id: GO:0034302
term: akinete formation
ontology: BP
definition:
The process in which an akinete, a thick-walled (encysted) dormant cell derived from the enlargement of a vegetative cell, is formed. Akinetes typically have granular cytoplasm, are more resistant to environmental extremes than vegetative cells, and are characteristic of several groups of Cyanobacteria.


go_id: GO:0034303
term: myxospore formation
ontology: BP
definition:
The process in which differentiated, resting cells are formed, usually within a fruiting body by Myxobacteria. The myxospore is more resistant to high temperature, dessication, and UV than vegetative myxobacteria.


go_id: GO:0034304
term: actinomycete-type spore formation
ontology: BP
definition:
The process in which differentiated, resting cells are formed from a substrate mycelium; characteristic of many members of the order Actinomycetales.


go_id: GO:0034305
term: regulation of asexual sporulation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of spore formation from the products of mitosis.


go_id: GO:0034306
term: regulation of sexual sporulation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of spore formation from the products of meiosis. An example of this is found in Saccharomyces cerevisiae.


go_id: GO:0034307
term: regulation of ascospore formation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of ascospore formation. An example of this process is found in Saccharomyces cerevisiae.


go_id: GO:0034308
term: primary alcohol metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.


go_id: GO:0034309
term: primary alcohol biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.


go_id: GO:0034310
term: primary alcohol catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.


go_id: GO:0034311
term: diol metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving a diol, a compound that contains two hydroxy groups, generally assumed to be, but not necessarily, alcoholic.


go_id: GO:0034312
term: diol biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a diol, any alcohol containing two hydroxyl groups attached to saturated carbon atoms.


go_id: GO:0034313
term: diol catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of a diol, any alcohol containing two hydroxyl groups attached to saturated carbon atoms.


go_id: GO:0034314
term: Arp2/3 complex-mediated actin nucleation
ontology: BP
definition:
The actin nucleation process in which actin monomers combine to form a new branch on the side of an existing actin filament; mediated by the Arp2/3 protein complex and its interaction with other proteins.


go_id: GO:0034315
term: regulation of Arp2/3 complex-mediated actin nucleation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of actin nucleation mediated by the Arp2/3 complex and interacting proteins.


go_id: GO:0034316
term: negative regulation of Arp2/3 complex-mediated actin nucleation
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of actin nucleation mediated by the Arp2/3 complex and interacting proteins.


go_id: GO:0034329
term: cell junction assembly
ontology: BP
definition:
A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a cell junction.


go_id: GO:0034330
term: cell junction organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell junction. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix.


go_id: GO:0034331
term: cell junction maintenance
ontology: BP
definition:
The organization process that preserves a cell junction in a stable functional or structural state. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix.


go_id: GO:0034332
term: adherens junction organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments.


go_id: GO:0034333
term: adherens junction assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form an adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments.


go_id: GO:0034334
term: adherens junction maintenance
ontology: BP
definition:
The maintenance of an adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments.


go_id: GO:0034335
term: DNA negative supercoiling activity
ontology: MF
definition:
Catalytic introduction of negative supercoils into a DNA molecule or region thereof. In bacteria, negative supercoils are only introduced by DNA gyrase, a type II topoisomerase, but not all DNA gyrases are capable of introducing supercoils. In bacteria, the level of supercoiling varies widely between species and has been characterized properly in only a handful of organisms. The best characterized enzyme, from E.coli, is exceptionally proficient at supercoiling and this ability is not representative of all bacteria.


go_id: GO:0034337
term: RNA folding
ontology: BP
definition:
The process of assisting in the covalent and noncovalent assembly of single or multimeric RNAs into the correct tertiary structure.


go_id: GO:0034338
term: short-chain carboxylesterase activity
ontology: MF
definition:
Catalysis of the reaction: a carboxylic ester + H2O = an alcohol + a carboxylic anion, where the carboxylic chain has 8 or fewer carbon atoms.


go_id: GO:0034340
term: response to type I interferon
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type I interferon stimulus. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.


go_id: GO:0034341
term: response to interferon-gamma
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon-gamma is also known as type II interferon.


go_id: GO:0034342
term: response to type III interferon
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type III interferon stimulus. Interferon lambda is the only member of the type III interferon found so far.


go_id: GO:0034343
term: type III interferon production
ontology: BP
definition:
The appearance of type III interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon lambda is the only member of the type III interferon found so far.


go_id: GO:0034344
term: regulation of type III interferon production
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far.


go_id: GO:0034345
term: negative regulation of type III interferon production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far.


go_id: GO:0034346
term: positive regulation of type III interferon production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far.


go_id: GO:0034347
term: type III interferon binding
ontology: MF
definition:
Binding to a type III interferon. Interferon lambda is the only member of the type III interferon found so far.


go_id: GO:0034348
term: type III interferon receptor activity
ontology: MF
definition:
Combining with a type III interferon and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Interferon lambda is the only member of the type III interferon found so far.


go_id: GO:0034351
term: negative regulation of glial cell apoptotic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of glial cell apoptotic process.


go_id: GO:0034352
term: positive regulation of glial cell apoptotic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of glial cell apoptotic process.


go_id: GO:0034353
term: mRNA 5'-diphosphatase activity
ontology: MF
definition:
Catalysis of the removal of a 5' terminal diphosphate from the 5'-triphosphate end of an mRNA, leaving a 5'-monophosphate end.


go_id: GO:0034354
term: 'de novo' NAD biosynthetic process from tryptophan
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of tryptophan from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.


go_id: GO:0034355
term: NAD salvage
ontology: BP
definition:
Any process that generates nicotinamide adenine dinucleotide (NAD) from derivatives of it, without de novo synthesis; salvage is usually from the degradation products nicotinic acid (Na) and nicotinamide (Nam).


go_id: GO:0034356
term: NAD biosynthesis via nicotinamide riboside salvage pathway
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD) from the vitamin precursor nicotinamide riboside.


go_id: GO:0034357
term: photosynthetic membrane
ontology: CC
definition:
A membrane enriched in complexes formed of reaction centers, accessory pigments and electron carriers, in which photosynthetic reactions take place.


go_id: GO:0034358
term: plasma lipoprotein particle
ontology: CC
definition:
A spherical particle with a hydrophobic core of triglycerides and/or cholesterol esters, surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins. Plasma lipoprotein particles transport lipids, which are non-covalently associated with the particles, in the blood or lymph.


go_id: GO:0034359
term: mature chylomicron
ontology: CC
definition:
A chylomicron that contains apolipoprotein C2 (APOC2), a cofactor for lipoprotein lipase (LPL) activity, and has a mean diameter of 500 nm and density of 0.95g/ml. Mature chylomicron particles transport exogenous (dietary) lipids from the intestines to other body tissues, via the blood and lymph.


go_id: GO:0034360
term: chylomicron remnant
ontology: CC
definition:
A lipoprotein particle that is derived from a mature chylomicron particle by the removal of triglycerides from the chylomicron core by lipoprotein lipase and the subsequent loss of surface components. It characteristically contains apolipoprotein E (APOE) and is cleared from the blood by the liver.


go_id: GO:0034361
term: very-low-density lipoprotein particle
ontology: CC
definition:
A triglyceride-rich lipoprotein particle that is typically composed of APOB100, APOE and APOCs and has a density of about 1.006 g/ml and a diameter of between 20-80 nm. It is found in blood and transports endogenous products (newly synthesized cholesterol and triglycerides) from the liver.


go_id: GO:0034362
term: low-density lipoprotein particle
ontology: CC
definition:
A lipoprotein particle, rich in cholesterol esters and low in triglycerides that is typically composed of APOB100 and APOE and has a density of 1.02-1.06 g/ml and a diameter of between 20-25 nm. LDL particles are formed from VLDL particles (via IDL) by the loss of triglyceride and gain of cholesterol ester. They transport endogenous cholesterol (and to some extent triglycerides) from peripheral tissues back to the liver.


go_id: GO:0034363
term: intermediate-density lipoprotein particle
ontology: CC
definition:
A triglyceride-rich lipoprotein particle that typically contains APOB100, APOE and APOCs and has a density of 1.006-1.019 g/ml and a diameter of between 25-30 nm. IDL particles are found in blood and are formed by the delipidation of very-low-density lipoprotein particles (VLDL). IDL particles are removed from blood by the liver, following binding to the APOE receptor, or are converted to low-density lipoprotein (LDL).


go_id: GO:0034364
term: high-density lipoprotein particle
ontology: CC
definition:
A lipoprotein particle with a high density (typically 1.063-1.21 g/ml) and a diameter of 5-10 nm that contains APOAs and may contain APOCs and APOE; found in blood and carries lipids from body tissues to the liver as part of the reverse cholesterol transport process.


go_id: GO:0034365
term: discoidal high-density lipoprotein particle
ontology: CC
definition:
A newly formed high-density lipoprotein particle; consists of a phospholipid bilayer surrounded by two or more APOA1 molecules. The discoidal HDL particle is formed when lipid-free or lipid-poor APOA1 acquires phospholipids and unesterified cholesterol from either cell membranes or triglyceride-rich lipoproteins (undergoing lipolysis by lipoprotein lipase).


go_id: GO:0034366
term: spherical high-density lipoprotein particle
ontology: CC
definition:
A mature high-density lipoprotein (HDL) particle, converted from discoidal HDL particles following the esterification of cholesterol in the particle by phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT).


go_id: GO:0034367
term: protein-containing complex remodeling
ontology: BP
definition:
The acquisition, loss, or modification of macromolecules within a complex, resulting in the alteration of an existing complex.


go_id: GO:0034369
term: plasma lipoprotein particle remodeling
ontology: BP
definition:
The acquisition, loss or modification of a protein or lipid within a plasma lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the esterification of cholesterol by phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT).


go_id: GO:0034370
term: triglyceride-rich lipoprotein particle remodeling
ontology: BP
definition:
The acquisition, loss or modification of a protein or lipid within a triglyceride-rich lipoprotein particle, including the hydrolysis of triglyceride by lipoprotein lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride from a triglyceride-rich lipoprotein particle.


go_id: GO:0034371
term: chylomicron remodeling
ontology: BP
definition:
The acquisition, loss or modification of a protein or lipid within a chylomicron, including the hydrolysis of triglyceride by lipoprotein lipase and the subsequent loss of free fatty acid.


go_id: GO:0034372
term: very-low-density lipoprotein particle remodeling
ontology: BP
definition:
The acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid.


go_id: GO:0034373
term: intermediate-density lipoprotein particle remodeling
ontology: BP
definition:
The acquisition, loss or modification of a protein or lipid within an intermediate-density lipoprotein particle.


go_id: GO:0034374
term: low-density lipoprotein particle remodeling
ontology: BP
definition:
The acquisition, loss or modification of a protein or lipid within a low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters from LDL to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride to LDL.


go_id: GO:0034375
term: high-density lipoprotein particle remodeling
ontology: BP
definition:
The acquisition, loss or modification of a protein or lipid within a high-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters from LDL to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride to LDL.


go_id: GO:0034376
ontology: BP
term:
conversion of discoidal high-density lipoprotein particle to spherical high-density lipoprotein particle

definition:
The process in which a discoidal high-density lipoprotein (HDL) particle acquires additional lipid or protein molecules, and cholesterol in the particle is converted to tightly bound cholesterol esters by the action of phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT), resulting in the formation of a spherical HDL particle.


go_id: GO:0034377
term: plasma lipoprotein particle assembly
ontology: BP
definition:
The non-covalent aggregation and arrangement of proteins and lipids to form a plasma lipoprotein particle.


go_id: GO:0034378
term: chylomicron assembly
ontology: BP
definition:
The non-covalent aggregation and arrangement of proteins and lipids in the intestine to form a chylomicron.


go_id: GO:0034379
term: very-low-density lipoprotein particle assembly
ontology: BP
definition:
The non-covalent aggregation and arrangement of proteins and lipids in the liver to form a very-low-density lipoprotein particle.


go_id: GO:0034380
term: high-density lipoprotein particle assembly
ontology: BP
definition:
The non-covalent aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle.


go_id: GO:0034381
term: plasma lipoprotein particle clearance
ontology: BP
definition:
The process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.


go_id: GO:0034382
term: chylomicron remnant clearance
ontology: BP
definition:
The process in which a chylomicron remnant is removed from the blood via receptor-mediated endocytosis into liver cells and its constituent parts degraded.


go_id: GO:0034383
term: low-density lipoprotein particle clearance
ontology: BP
definition:
The process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.


go_id: GO:0034384
term: high-density lipoprotein particle clearance
ontology: BP
definition:
The process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.


go_id: GO:0034385
term: triglyceride-rich plasma lipoprotein particle
ontology: CC
definition:
A plasma lipoprotein particle that has a hydrophobic core enriched in triglycerides surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins. Triglyceride-rich lipoprotein particles transport lipids, which are non-covalently associated with the particles, in the blood.


go_id: GO:0034386
term: 4-aminobutyrate:2-oxoglutarate transaminase activity
ontology: MF
definition:
Catalysis of the reaction: 4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate.


go_id: GO:0034388
term: Pwp2p-containing subcomplex of 90S preribosome
ontology: CC
definition:
A protein complex that forms a subcomplex of the 90S preribosome and can interact directly with the 5' External Transcribed Spacer (ETS) of the full length pre-rRNA transcript. In S. cerevisiae, it sediments at 25-30 S and is composed of Pwp2p, Dip2p, Utp21p, Utp13p, Utp18p, and Utp6p.


go_id: GO:0034389
term: lipid droplet organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lipid particle.


go_id: GO:0034390
term: smooth muscle cell apoptotic process
ontology: BP
definition:
Any apoptotic process in a smooth muscle cell. Smooth muscle consists of non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels.


go_id: GO:0034392
term: negative regulation of smooth muscle cell apoptotic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell apoptotic process.


go_id: GO:0034393
term: positive regulation of smooth muscle cell apoptotic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of smooth muscle cell apoptotic process.


go_id: GO:0034394
term: protein localization to cell surface
ontology: BP
definition:
A process in which a protein is transported to, or maintained in, a location within the external part of the cell wall and/or plasma membrane.


go_id: GO:0034395
term: regulation of transcription from RNA polymerase II promoter in response to iron
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to an iron stimulus.


go_id: GO:0034396
term: negative regulation of transcription from RNA polymerase II promoter in response to iron
ontology: BP
definition:
Any process that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter in response to an iron stimulus.


go_id: GO:0034400
term: gerontoplast
ontology: CC
definition:
A plastid found in senescing, formerly green tissues that is derived from a chloroplast that undergoes an organized developmental program of senescence.


go_id: GO:0034402
term: recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex
ontology: BP
definition:
The process in which proteins required for 3'-end transcript processing become associated with the RNA polymerase II holoenzyme complex and the 3' end of a transcript.


go_id: GO:0034403
term: alignment of 3' and 5' splice sites of mRNA
ontology: BP
definition:
Recognition of both the 5' and 3'-splice sites and positioning them in the correct alignment with respect to each other so that the second catalytic step of nuclear mRNA splicing can occur.


go_id: GO:0034404
term: nucleobase-containing small molecule biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide.


go_id: GO:0034405
term: response to fluid shear stress
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluid shear stress stimulus. Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface.


go_id: GO:0034406
term: cell wall beta-glucan metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of cells.


go_id: GO:0034407
term: cell wall (1->3)-beta-D-glucan metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells.


go_id: GO:0034408
term: ascospore wall beta-glucan metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores.


go_id: GO:0034409
term: ascospore wall (1->3)-beta-D-glucan metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of ascospores.


go_id: GO:0034410
term: cell wall beta-glucan biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of cells.


go_id: GO:0034411
term: cell wall (1->3)-beta-D-glucan biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells.


go_id: GO:0034412
term: ascospore wall beta-glucan biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores.


go_id: GO:0034413
term: ascospore wall (1->3)-beta-D-glucan biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of ascospores.


go_id: GO:0034414
term: tRNA 3'-trailer cleavage, endonucleolytic
ontology: BP
definition:
Endonucleolytic cleavage of the 3'-end of the pre-tRNA as part of the process of generating the mature 3'-end of the tRNA.


go_id: GO:0034415
term: tRNA 3'-trailer cleavage, exonucleolytic
ontology: BP
definition:
Exonucleolytic cleavage of the 3'-end of the pre-tRNA as part of the process of generating the mature 3'-end of the tRNA.


go_id: GO:0034418
term: urate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of urate, the anion of uric acid, 2,6,8-trioxypurine.


go_id: GO:0034420
term: co-translational protein acetylation
ontology: BP
definition:
The addition of an acetyl group to one or more amino acids in a protein, occurring before the protein has been completely translated and released from the ribosome.


go_id: GO:0034421
term: post-translational protein acetylation
ontology: BP
definition:
The addition of an acetyl group to one or more amino acids in a protein, occurring after the protein has been completely translated and released from the ribosome.


go_id: GO:0034424
term: Vps55/Vps68 complex
ontology: CC
definition:
A membrane-associated protein complex that is required for a late stage of endosomal transport. In budding yeast, this complex consists of Vps55p and Vps68p proteins.


go_id: GO:0034425
term: etioplast envelope
ontology: CC
definition:
The double lipid bilayer enclosing the etioplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.


go_id: GO:0034427
term: nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of the mRNA transcript body that occurs when the 3' end is not protected by a 3'-poly(A) tail; degradation proceeds in the 3' to 5' direction.


go_id: GO:0034428
term: nuclear-transcribed mRNA catabolic process, exonucleolytic, 5'-3'
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of the mRNA transcript body that occurs when the 5' end is not protected by a 5'-cap; degradation proceeds in the 5' to 3' direction.


go_id: GO:0034429
term: tectobulbar tract morphogenesis
ontology: BP
definition:
Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the optic tectum towards target cells in the premotor reticulospinal system in the hindbrain.


go_id: GO:0034431
term: bis(5'-adenosyl)-hexaphosphatase activity
ontology: MF
definition:
Catalysis of the reaction: P1-P6-bis(5'-adenosyl) hexaphosphate + H2O = AMP + adenosine 5'-pentaphosphate.


go_id: GO:0034432
term: bis(5'-adenosyl)-pentaphosphatase activity
ontology: MF
definition:
Catalysis of the reaction: P1-P6-bis(5'-adenosyl) pentaphosphate + H2O = AMP + adenosine 5'-tetraphosphate.


go_id: GO:0034433
term: steroid esterification
ontology: BP
definition:
A lipid modification process in which a steroid ester is formed by the combination of a carboxylic acid (often a fatty acid) and a steroid molecule (e.g. cholesterol).


go_id: GO:0034434
term: sterol esterification
ontology: BP
definition:
A lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and a sterol molecule (e.g. cholesterol).


go_id: GO:0034435
term: cholesterol esterification
ontology: BP
definition:
A lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and cholesterol. In the blood this process is associated with the conversion of free cholesterol into cholesteryl ester, which is then sequestered into the core of a lipoprotein particle.


go_id: GO:0034436
term: glycoprotein transport
ontology: BP
definition:
The directed movement of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0034440
term: lipid oxidation
ontology: BP
definition:
The removal of one or more electrons from a lipid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen.


go_id: GO:0034441
term: plasma lipoprotein particle oxidation
ontology: BP
definition:
The modification of a lipid or protein within a plasma lipoprotein particle by oxidation of the lipid or one or more amino acids.


go_id: GO:0034443
term: negative regulation of lipoprotein oxidation
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of lipoprotein oxidation.


go_id: GO:0034444
term: regulation of plasma lipoprotein oxidation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of lipoprotein oxidation, occurring in the blood plasma.


go_id: GO:0034445
term: negative regulation of plasma lipoprotein oxidation
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of lipoprotein particle oxidation, occurring in the blood plasma.


go_id: GO:0034446
term: substrate adhesion-dependent cell spreading
ontology: BP
definition:
The morphogenetic process that results in flattening of a cell as a consequence of its adhesion to a substrate.


go_id: GO:0034447
term: very-low-density lipoprotein particle clearance
ontology: BP
definition:
The process in which a very-low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.


go_id: GO:0034450
term: ubiquitin-ubiquitin ligase activity
ontology: MF
definition:
Isoenergetic transfer of ubiquitin from one protein to an existing ubiquitin chain via the reaction X-ubiquitin + Y-ubiquitin -> Y-ubiquitin-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue.


go_id: GO:0034451
term: centriolar satellite
ontology: CC
definition:
A small (70-100 nm) cytoplasmic granule that contains a number of centrosomal proteins; centriolar satellites traffic toward microtubule minus ends and are enriched near the centrosome.


go_id: GO:0034454
term: microtubule anchoring at centrosome
ontology: BP
definition:
Any process in which a microtubule is maintained in a specific location in a cell by attachment to a centrosome.


go_id: GO:0034455
term: t-UTP complex
ontology: CC
definition:
A protein complex that forms a subcomplex of the 90S preribosome and is required for the subsequent assembly of the rest of the preribosome. In S. cerevisiae, it is composed of Utp5p, Utp4p, Nan1p, Utp8p, Utp9p, Utp10 and Utp15p.


go_id: GO:0034456
term: UTP-C complex
ontology: CC
definition:
A protein complex that forms a subcomplex of the 90S preribosome. In S. cerevisiae, it is composed of Rrp7p, Utp22p, Ckb1p, Cka1p, Ckb2p and Cka2p.


go_id: GO:0034457
term: Mpp10 complex
ontology: CC
definition:
A protein complex that forms a subcomplex of the 90S preribosome. In S. cerevisiae, it is composed of Mpp10p, Imp3p and Imp4p.


go_id: GO:0034461
term: uropod retraction
ontology: BP
definition:
The process in which a uropod detaches from the cell substrate and retracts the rear of a migrating cell.


go_id: GO:0034462
term: small-subunit processome assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of proteins and RNA molecules to form a small-subunit processome.


go_id: GO:0034463
term: 90S preribosome assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of proteins and RNA molecules to form a 90S preribosome. The 90S preribosome represents the complex that forms on the primary rRNA transcript before it splits into the small subunit and large subunit portions.


go_id: GO:0034464
term: BBSome
ontology: CC
definition:
A ciliary protein complex involved in cilium biogenesis. It consists of at least seven Bardet-Biedl syndrome (BBS) proteins and BBIP10. It moves in association with IFT trains through cilia (likely as an IFT-A/B adaptor or cargo), and is required for the integrity of IFT-A and IFT-B.


go_id: GO:0034465
term: response to carbon monoxide
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon monoxide (CO) stimulus.


go_id: GO:0034469
term: Golgi stack lumen
ontology: CC
definition:
The volume enclosed by any of the membranes of the thin, flattened cisternae that form the central portion of the Golgi complex.


go_id: GO:0034470
term: ncRNA processing
ontology: BP
definition:
Any process that results in the conversion of one or more primary non-coding RNA (ncRNA) transcripts into one or more mature ncRNA molecules.


go_id: GO:0034478
term: phosphatidylglycerol catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of phosphatidylglycerols, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of glycerol.


go_id: GO:0034479
term: phosphatidylglycerol phospholipase C activity
ontology: MF
definition:
Catalysis of the reaction: a phosphatidylglycerol + H2O = 1,2-diacylglycerol + glycerol 3-phosphate.


go_id: GO:0034480
term: phosphatidylcholine phospholipase C activity
ontology: MF
definition:
Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-sn-glycerol + H+ + phosphocholine.


go_id: GO:0034481
term: chondroitin sulfotransferase activity
ontology: MF
definition:
Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin sulfate.


go_id: GO:0034482
term: chondroitin 2-O-sulfotransferase activity
ontology: MF
definition:
Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 2'-O-sulfate. Results in sulfation of glucuronic acid and iduronic acid residues.


go_id: GO:0034483
term: heparan sulfate sulfotransferase activity
ontology: MF
definition:
Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5'-bisphosphate + sulfated heparan sulfate.


go_id: GO:0034484
term: raffinose catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of raffinose, the trisaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.


go_id: GO:0034485
term: phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity
ontology: MF
definition:
Catalysis of the reaction: phosphatidylinositol-3,4,5-trisphosphate + H2O = phosphatidylinositol-3,4-bisphosphate + phosphate.


go_id: GO:0034487
term: vacuolar amino acid transmembrane transport
ontology: BP
definition:
The process in which an amino acid is transported from one side of the vacuolar membrane to the other.


go_id: GO:0034497
term: protein localization to phagophore assembly site
ontology: BP
definition:
Any process in which a protein is transported to, or maintained at, the phagophore assembly site (PAS).


go_id: GO:0034502
term: protein localization to chromosome
ontology: BP
definition:
Any process in which a protein is transported to, or maintained at, a specific location on a chromosome.


go_id: GO:0034503
term: protein localization to nucleolar rDNA repeats
ontology: BP
definition:
Any process in which a protein is transported to, or maintained at, the rDNA repeats on a chromosome in the nucleolus.


go_id: GO:0034504
term: protein localization to nucleus
ontology: BP
definition:
A process in which a protein transports or maintains the localization of another protein to the nucleus.


go_id: GO:0034505
term: tooth mineralization
ontology: BP
definition:
The process in which calcium salts are deposited into calcareous tooth structures such as dental enamel, dentin and cementum.


go_id: GO:0034506
term: chromosome, centromeric core domain
ontology: CC
definition:
The innermost portion of the centromeric region of a chromosome, encompassing the core region of a chromosome centromere and the proteins that bind to it.


go_id: GO:0034507
term: chromosome, centromeric outer repeat region
ontology: CC
definition:
The portion of the centromeric region of a chromosome that flanks the core region, encompassing repeated regions of a chromosome centromere and the proteins that bind to it.


go_id: GO:0034508
term: centromere complex assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of proteins and centromeric DNA molecules to form a centromeric protein-DNA complex. Includes the formation of the chromatin structures which form a platform for the kinetochore, and assembly of the kinetochore onto this specialized chromatin. In fission yeast and higher eukaryotes this process also includes the formation of heterochromatin at the outer repeat (pericentric) regions of the centromere.


go_id: GO:0034510
term: centromere separation
ontology: BP
definition:
The cell cycle process in which centromeres are physically detached from each other during chromosome separation.


go_id: GO:0034514
term: mitochondrial unfolded protein response
ontology: BP
definition:
The series of molecular signals generated as a consequence of the presence of unfolded proteins in the mitochondrial matrix; results in transcriptional upregulation of nuclear genes encoding mitochondrial stress proteins.


go_id: GO:0034515
term: proteasome storage granule
ontology: CC
definition:
An aggregation of proteasome core protease (CP) and regulatory particle (RP) complexes that localizes in the cytoplasm as dot-like structures when cells are in a quiescent state.


go_id: GO:0034516
term: response to vitamin B6
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B6 stimulus. Vitamin B6 encompasses pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate.


go_id: GO:0034517
term: ribophagy
ontology: BP
definition:
The selective autophagy process in which cells degrade mature ribosomes under conditions of starvation.


go_id: GO:0034518
term: RNA cap binding complex
ontology: CC
definition:
Any protein complex that binds to a specialized RNA cap structure at any time in the lifetime of the RNA.


go_id: GO:0034519
term: cytoplasmic RNA cap binding complex
ontology: CC
definition:
A protein complex found in the cytoplasm that binds the 5' cap structure of an mRNA, and typically consists of the cap-binding protein eIF4E, the adaptor protein eIF4G, and a multi-factor complex comprising eIF1, eIF2, eIF3 and eIF5. This complex mediates recruitment of the 40S subunit to mRNA.


go_id: GO:0034521
term: 1-naphthoic acid dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 1-naphthoic acid + NADH + O2 + H+ = cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene + NAD+.


go_id: GO:0034522
term: cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene = 1,2-dihydroxy-8-carboxynaphthalene + 2 H+ + 2 e-.


go_id: GO:0034523
term: 3-formylsalicylate oxidase activity
ontology: MF
definition:
Catalysis of the reaction: 3-formylsalicylic acid + O2 + H2O = 2-hydroxyisophthalic acid + hydrogen peroxide.


go_id: GO:0034526
term: 2-methylnaphthalene hydroxylase activity
ontology: MF
definition:
Catalysis of the reaction: 2-methylnaphthalene + NADH + O2 + H+ = 2-hydroxymethylnaphthalene + NAD+ + H2O.


go_id: GO:0034527
term: 1,2-dihydroxy-8-carboxynaphthalene dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 1,2-dihydroxy-8-carboxynaphthalene + O2 = 2-carboxy-2-hydroxy-8-carboxychromene.


go_id: GO:0034528
term: 2-carboxy-2-hydroxy-8-carboxychromene isomerase activity
ontology: MF
definition:
Catalysis of the reaction: 2-carboxy-2-hydroxy-8-carboxychromene = 2-hydroxy-3-carboxybenzalpyruvate.


go_id: GO:0034529
term: 2-hydroxy-3-carboxy-benzalpyruvate hydratase-aldolase activity
ontology: MF
definition:
Catalysis of the reaction: 2-hydroxy-3-carboxybenzalpyruvate + H2O = 3-formylsalicylic acid + pyruvate.


go_id: GO:0034530
term: 4-hydroxymethylsalicyaldehyde dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 4-hydroxymethylsalicylaldehyde + NAD+ + H2O = 4-hydroxymethylsalicylate + NADH + 2 H+.


go_id: GO:0034531
term: 2-hydroxy-4-hydroxymethylbenzalpyruvate hydratase-aldolase activity
ontology: MF
definition:
Catalysis of the reaction: 2-hydroxy-4-hydroxymethylbenzalpyruvate + H2O = pyruvate + 4-hydroxymethylsalicylaldehyde.


go_id: GO:0034532
term: 2-hydroxy-7-hydroxymethylchromene-2-carboxylate isomerase activity
ontology: MF
definition:
Catalysis of the reaction: 2-hydroxy-7-hydroxymethylchromene-2-carboxylate = 2-hydroxy-4-hydroxymethylbenzalpyruvate.


go_id: GO:0034533
term: 1,2-dihydroxy-7-hydroxymethylnaphthalene dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 1,2-dihydroxy-7-hydroxymethylnaphthalene + O2 = 2-hydroxy-7-hydroxymethylchromene-2-carboxylate.


go_id: GO:0034534
term: 1-methylnaphthalene hydroxylase activity
ontology: MF
definition:
Catalysis of the reaction: 1-methylnaphthalene + NADH + H+ + O2 = 1-hydroxymethylnaphthalene + NAD+ + H2O.


go_id: GO:0034535
term: 1,2-dihydroxy-8-methylnaphthalene dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 1,2-dihydroxy-8-methylnaphthalene + O2 = 2-hydroxy-8-methylchromene-2-carboxylate + H+.


go_id: GO:0034536
term: 2-hydroxy-8-methylchromene-2-carboxylate isomerase activity
ontology: MF
definition:
Catalysis of the reaction: 2-hydroxy-8-methylchromene-2-carboxylate = 2-hydroxy-3-methylbenzalpyruvate.


go_id: GO:0034537
term: 2-hydroxy-3-methylbenzalpyruvate hydratase-aldolase activity
ontology: MF
definition:
Catalysis of the reaction: 2-hydroxy-3-methylbenzalpyruvate + H2O = pyruvate + 3-methylsalicylaldehyde.


go_id: GO:0034539
term: 3,3',5,5'-tetrabromobisphenol A reductive dehalogenase activity
ontology: MF
definition:
Catalysis of the reaction: 3,3',5,5'-tetrabromobisphenol A + 2 H+ + 2 e- = 3,3',5-tribromobisphenol A + HBr.


go_id: GO:0034544
term: trans-ACOHDA hydrolase activity
ontology: MF
definition:
Catalysis of the reaction: trans-4-amino-6-carboxy-2-oxo-hexa-3,5-dienoate + H2O = fumarylpyruvate + NH3.


go_id: GO:0034551
term: mitochondrial respiratory chain complex III assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form the cytochrome bc(1) complex (also known as ubiquinol-cytochrome c reductase), in the mitochondrial inner membrane.


go_id: GO:0034552
term: respiratory chain complex II assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex II.


go_id: GO:0034553
term: mitochondrial respiratory chain complex II assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex II, in the mitochondrial inner membrane.


go_id: GO:0034554
term: 3,3',5-tribromobisphenol A reductive dehalogenase activity
ontology: MF
definition:
Catalysis of the reaction: 3,3',5-tribromobisphenol A + 2 H+ + 2 e- = 3,3'-dibromobisphenol A + HBr.


go_id: GO:0034559
term: bisphenol A hydroxylase B activity
ontology: MF
definition:
Catalysis of the reaction: bisphenol A + NADH + H+ + O2 = 1,2-bis(4-hydroxyphenyl)-2-propanol + NAD+ + H2O.


go_id: GO:0034560
term: bisphenol A hydroxylase A activity
ontology: MF
definition:
Catalysis of the reaction: bisphenol A + NADH + H+ + O2 = 2,2-bis(4-hydroxyphenyl)-1-propanol + NAD+ + H2O.


go_id: GO:0034561
term: 1,2-bis(4-hydroxyphenyl)-2-proponol dehydratase activity
ontology: MF
definition:
Catalysis of the reaction: 1,2-bis(4-hydroxyphenyl)-2-propanol = 4,4'-dihydroxy-alpha-methylstilbene + H2O.


go_id: GO:0034562
term: 2,2-bis(4-hydroxyphenyl)-1-propanol hydroxylase activity
ontology: MF
definition:
Catalysis of the reaction: 2,2-bis(4-hydroxyphenyl)-1-propanol + NADH + H+ + O2 = 2,3-bis(4-hydroxyphenyl)-1,2-propanediol + NAD+ + H2O.


go_id: GO:0034563
term: 2,3-bis(4-hydroxyphenyl)-1,2-propanediol dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 2,3-bis(4-hydroxyphenyl)-1,2-propanediol + O2 = 4-hydroxyphenacyl alcohol + 4-hydroxybenzoate + 2 H+ + 2 e-.


go_id: GO:0034564
term: 4,4'-dihydroxy-alpha-methylstilbene dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 4,4'-dihydroxy-alpha-methylstilbene + O2 = 4-hydroxybenzaldehyde + 4-hydroxyacetophenone + 2 H+ + 2 e-.


go_id: GO:0034565
term: 1-nitro-1,2-dihydro-1,3,5-triazine hydrolase activity
ontology: MF
definition:
Catalysis of the reaction: 1-nitro-1,2-dihydro-1,3,5-triazine + 2 H2O = 1-nitro-1,3,5-triazinane-2,4-diol.


go_id: GO:0034568
term: isoproturon dimethylaminedehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: isoproturon + H2O = formaldehyde + monodemethylisoproturon + 2 H+ + 2 e-.


go_id: GO:0034569
term: monodemethylisoproturon dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: monodemethylisoproturon + H2O = hydroxymonodemethylisoproturon + 2 H+ + 2 e-.


go_id: GO:0034570
term: hydroxymonomethylisoproturon dimethylaminedehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: hydroxymonodemethylisoproturon + H2O = formaldehyde + 4'-(2-hydroxyisopropyl)phenylurea + 2 H+ + 2 e-.


go_id: GO:0034571
term: 4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity
ontology: MF
definition:
Catalysis of the reaction: 4'-(2-hydroxyisopropyl)phenylurea + H2O = 4'-(2-hydroxyisopropyl)phenylaniline + carbamic acid.


go_id: GO:0034572
term: monodemethylisoproturon dimethylaminedehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: monodemethylisoproturon + H2O = didemethylisoproturon + formaldehyde + 2 H+ + 2 e-.


go_id: GO:0034574
term: didemethylisoproturon dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: didemethylisoproturon + H2O = 4'-(2-hydroxyisopropyl)phenylurea + 2 H+ + 2 e-.


go_id: GO:0034575
term: 4-isopropylaniline dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 4-isopropylaniline + H2O = 4'-(2-hydroxyisopropyl)phenylaniline + 2 H+ + 2 e-.


go_id: GO:0034582
term: 3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 3-hydroxy-4-methyloctanoyl-CoA = 4-methyl-3-oxooctanoyl-CoA + 2 H+ + 2 e-.


go_id: GO:0034583
term: 21U-RNA binding
ontology: MF
definition:
Binding to a 21U-RNA, a 21-nucleotide RNA characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome.


go_id: GO:0034584
term: piRNA binding
ontology: MF
definition:
Binding to a piRNA, a Piwi-associated RNA, a 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.


go_id: GO:0034585
term: 21U-RNA metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving 21U-RNAs, a class of single-stranded RNA molecules of about 21 nucleotides in length characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome.


go_id: GO:0034586
term: 21U-RNA catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of 21U-RNAs, a class of single-stranded RNA molecules of about 21 nucleotides in length characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome.


go_id: GO:0034587
term: piRNA metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.


go_id: GO:0034588
term: piRNA catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.


go_id: GO:0034589
term: hydroxyproline transport
ontology: BP
definition:
The directed movement of hydroxyproline into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0034593
term: phosphatidylinositol bisphosphate phosphatase activity
ontology: MF
definition:
Catalysis of the reaction: phosphatidylinositol bisphosphate + H2O = phosphatidylinositol phosphate + phosphate.


go_id: GO:0034594
term: phosphatidylinositol trisphosphate phosphatase activity
ontology: MF
definition:
Catalysis of the reaction: phosphatidylinositol trisphosphate + H2O = phosphatidylinositol bisphosphate + phosphate.


go_id: GO:0034597
term: phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity
ontology: MF
definition:
Catalysis of the reaction: 1-phosphatidyl-myo-inositol 4,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate.


go_id: GO:0034598
term: phosphothreonine lyase activity
ontology: MF
definition:
Catalysis of the removal of the phosphate group from phosphothreonine by cleavage of the C-OP bond with the concomitant abstraction of the alpha proton, generating a double bond-containing product.


go_id: GO:0034599
term: cellular response to oxidative stress
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.


go_id: GO:0034605
term: cellular response to heat
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.


go_id: GO:0034606
term: response to hermaphrodite contact
ontology: BP
definition:
The response by the male to a hermaphrodite after initial contact following mate finding. The male stops forward locomotion, presses the ventral side of his tail against his partner's body, and begins moving backward along the hermaphrodite. Male response behavior is initiated when sensory neurons located in the rays of his tail contact a potential mate.


go_id: GO:0034607
term: turning behavior involved in mating
ontology: BP
definition:
The sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail.


go_id: GO:0034608
term: vulval location
ontology: BP
definition:
Location, by the male, of his partner's vulva when backing along the ventral side of the hermaphrodite during mating. The male stops at the vulva, coordinates his movements to the hermaphrodite's, and positions his tail precisely over the vulva so that he may insert his spicules and ejaculate.


go_id: GO:0034609
term: spicule insertion
ontology: BP
definition:
Insertion of the male copulatory spicules into the hermaphrodite. Spicule insertion behavior initiates when the male cloaca contacts the vulva. During most mating encounters, the spicule tips will prod the vulva continuously until they partially penetrate, which then causes the protractors to contract completely so that the spicules extend through the vulva.


go_id: GO:0034610
term: oligodeoxyribonucleotidase activity
ontology: MF
definition:
Catalysis of the exonucleolytic cleavage of oligodeoxyribonucleotides to yield deoxyribonucleoside 5'-phosphates.


go_id: GO:0034611
term: oligoribonucleotidase activity
ontology: MF
definition:
Catalysis of the exonucleolytic cleavage of oligoribonucleotides to yield ribonucleoside 5'-phosphates.


go_id: GO:0034612
term: response to tumor necrosis factor
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus.


go_id: GO:0034614
term: cellular response to reactive oxygen species
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.


go_id: GO:0034615
term: GCH1 complex
ontology: CC
definition:
A protein complex that possesses GTP cyclohydrolase I activity. In E. coli and human, the complex is a homodecamer, and monomers are catalytically inactive.


go_id: GO:0034616
term: response to laminar fluid shear stress
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a laminar fluid shear stress stimulus. Laminar fluid flow is the force acting on an object in a system where the fluid is moving across a solid surface in parallel layers. As an example, laminar shear stress can be seen where blood flows against the luminal side of blood vessel walls.


go_id: GO:0034617
term: tetrahydrobiopterin binding
ontology: MF
definition:
Binding to a tetrahydrobiopterin, 5,6,7,8-tetrahydrobiopterin or a derivative thereof; tetrahydrobiopterins are enzyme cofactors that carry electrons in redox reactions.


go_id: GO:0034620
term: cellular response to unfolded protein
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.


go_id: GO:0034627
term: 'de novo' NAD biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of tryptophan or aspartate from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.


go_id: GO:0034628
term: 'de novo' NAD biosynthetic process from aspartate
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of aspartate from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.


go_id: GO:0034631
term: microtubule anchoring at spindle pole body
ontology: BP
definition:
Any process in which a microtubule is maintained in a specific location in a cell by attachment to a spindle pole body. Microtubules attach to spindle pole bodies at the minus end.


go_id: GO:0034632
term: retinol transmembrane transporter activity
ontology: MF
definition:
Enables the transfer of retinol from one side of a membrane to the other. Retinol is vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A.


go_id: GO:0034633
term: retinol transport
ontology: BP
definition:
The directed movement of retinol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Retinol is vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A.


go_id: GO:0034634
term: glutathione transmembrane transporter activity
ontology: MF
definition:
Enables the transfer of glutathione, the tripeptide glutamylcysteinylglycine, from one side of a membrane to the other.


go_id: GO:0034635
term: glutathione transport
ontology: BP
definition:
The directed movement of glutathione, the tripeptide glutamylcysteinylglycine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0034637
term: cellular carbohydrate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, carried out by individual cells.


go_id: GO:0034638
term: phosphatidylcholine catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.


go_id: GO:0034639
term: L-amino acid efflux transmembrane transporter activity
ontology: MF
definition:
Enables the transfer of an L-amino acid from the inside of the cell to the outside of the cell across a membrane.


go_id: GO:0034640
term: establishment of mitochondrion localization by microtubule attachment
ontology: BP
definition:
The directed movement of a mitochondrion by attachment to a microtubule, followed by elongation of the microtubule by tubulin polymerization.


go_id: GO:0034641
term: cellular nitrogen compound metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.


go_id: GO:0034643
term: establishment of mitochondrion localization, microtubule-mediated
ontology: BP
definition:
The directed movement of the mitochondrion to a specific location, by a process involving microtubules.


go_id: GO:0034644
term: cellular response to UV
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.


go_id: GO:0034645
term: cellular macromolecule biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells.


go_id: GO:0034647
term: histone H3-tri/di/monomethyl-lysine-4 demethylase activity
ontology: MF
definition:
Catalysis of the removal of a methyl group from a tri, a di or a monomethyl-lysine residue at position 4 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.


go_id: GO:0034650
term: cortisol metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving cortisol, the steroid hormone 11-beta-17,21-trihydroxypregn-4-ene-3,20-dione. Cortisol is synthesized from cholesterol in the adrenal gland and controls carbohydrate, fat and protein metabolism and has anti-inflammatory properties.


go_id: GO:0034651
term: cortisol biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of cortisol, the steroid hormone 11-beta-17,21-trihydroxypregn-4-ene-3,20-dione. Cortisol is synthesized from cholesterol in the adrenal gland and controls carbohydrate, fat and protein metabolism and has anti-inflammatory properties.


go_id: GO:0034653
term: retinoic acid catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of retinoic acid, one of the three components that makes up vitamin A.


go_id: GO:0034654
term: nucleobase-containing compound biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids.


go_id: GO:0034655
term: nucleobase-containing compound catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of nucleobases, nucleosides, nucleotides and nucleic acids.


go_id: GO:0034656
term: nucleobase-containing small molecule catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide.


go_id: GO:0034657
term: GID complex
ontology: CC
definition:
A protein complex with ubiquitin ligase activity that is involved in proteasomal degradation of fructose-1,6-bisphosphatase (FBPase) and phosphoenolpyruvate carboxykinase during the transition from gluconeogenic to glycolytic growth conditions. In S. cerevisiae, the GID (Glucose Induced degradation Deficient) complex consists of Vid30p, Rmd5p, Vid24p, Vid28p, Gid7p, Gid8p, and Fyv10p.


go_id: GO:0034659
term: isopropylmalate transport
ontology: BP
definition:
The directed movement of isopropylmalate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0034661
term: ncRNA catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of non-coding RNA transcripts (ncRNAs). Includes the breakdown of cryptic unstable transcripts (CUTs).


go_id: GO:0034662
term: CFTR-NHERF-ezrin complex
ontology: CC
definition:
A protein complex that contains ezrin, Na+/H+ exchanger regulatory factor (NHERF, also called EBP50), and two copies of the cystic fibrosis transmembrane conductance regulator (CFTR). The CFTR molecules interact with NHERF via their cytoplasmic tail domains; the complex is thought to link the CFTR channel to the actin cytoskeleton and contribute to the regulation of channel activity.


go_id: GO:0034663
term: endoplasmic reticulum chaperone complex
ontology: CC
definition:
A protein complex that is located in the endoplasmic reticulum and is composed of chaperone proteins, including BiP, GRP94; CaBP1, protein disulfide isomerase (PDI), ERdj3, cyclophilin B, ERp72, GRP170, UDP-glucosyltransferase, and SDF2-L1.


go_id: GO:0034664
term: Ig heavy chain-bound endoplasmic reticulum chaperone complex
ontology: CC
definition:
A protein complex that is located in the endoplasmic reticulum (ER) and is formed by the association of an immunoglobulin heavy chain with the proteins of the ER chaperone complex; the latter include BiP, GRP94; CaBP1, protein disulfide isomerase (PDI), ERdj3, cyclophilin B, ERp72, GRP170, UDP-glucosyltransferase, and SDF2-L1.


go_id: GO:0034671
ontology: BP
term:
retinoic acid receptor signaling pathway involved in pronephros anterior/posterior pattern specification

definition:
The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that results in the spatial identity of regions along the anterior-posterior axis of the pronephros.


go_id: GO:0034672
term: anterior/posterior pattern specification involved in pronephros development
ontology: BP
definition:
The developmental process that results in the creation of defined areas or spaces within the pronephros along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate.


go_id: GO:0034673
term: inhibin-betaglycan-ActRII complex
ontology: CC
definition:
A protein complex that consists of inhibin, type III transforming growth factor beta receptor (also known as betaglycan), and the type II activin receptor ActRII. The complex is thought to negatively regulate the activity of activin B.


go_id: GO:0034692
term: E.F.G complex
ontology: CC
definition:
A protein complex that comprises three core spliceosomal proteins, designated E, F, and G. Formation of the E.F.G complex is essential but not sufficient for the formation of a stable U1 snRNP complex.


go_id: GO:0034693
term: U11/U12 snRNP
ontology: CC
definition:
A ribonucleoprotein complex that is formed by the association of the U11 and U12 small nuclear ribonucleoproteins.


go_id: GO:0034694
term: response to prostaglandin
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin stimulus.


go_id: GO:0034695
term: response to prostaglandin E
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin E stimulus.


go_id: GO:0034696
term: response to prostaglandin F
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin F stimulus.


go_id: GO:0034697
term: response to prostaglandin I
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin I stimulus.


go_id: GO:0034698
term: response to gonadotropin
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin stimulus.


go_id: GO:0034699
term: response to luteinizing hormone
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a luteinizing hormone stimulus.


go_id: GO:0034702
term: ion channel complex
ontology: CC
definition:
A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.


go_id: GO:0034709
term: methylosome
ontology: CC
definition:
A large (20 S) protein complex that possesses protein arginine methyltransferase activity and modifies specific arginines to dimethylarginines in the arginine- and glycine-rich domains of several spliceosomal Sm proteins, thereby targeting these proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein (snRNP) core particles. Proteins found in the methylosome include the methyltransferase JBP1 (PRMT5), pICln (CLNS1A), MEP50 (WDR77), and unmethylated forms of SM proteins that have RG domains.


go_id: GO:0034711
term: inhibin binding
ontology: MF
definition:
Binding to an inhibin monomer, any of the polypeptides that combine to form activin and inhibin dimers.


go_id: GO:0034715
term: pICln-Sm protein complex
ontology: CC
definition:
A protein complex that contains pICln (CLNS1A) and several Sm proteins, including SmD1, SmD2, SmE, SmF, and SmG.


go_id: GO:0034716
term: Gemin3-Gemin4-Gemin5 complex
ontology: CC
definition:
A protein complex that contains Gemin3 (DDX20), Gemin4, and Gemin5, and can bind to snRNAs; may be an intermediate in SMN complex assembly.


go_id: GO:0034717
term: Gemin6-Gemin7-unrip complex
ontology: CC
definition:
A protein complex that contains Gemin6, Gemin7, and unrip (STRAP), and can bind to snRNAs; may play a role in snRNP assembly.


go_id: GO:0034718
term: SMN-Gemin2 complex
ontology: CC
definition:
A protein complex that contains the survival motor neuron (SMN) protein and Gemin2; may form the stable core of the larger SMN complex.


go_id: GO:0034719
term: SMN-Sm protein complex
ontology: CC
definition:
A protein complex formed by the association of several methylated Sm proteins with the SMN complex; the latter contains the survival motor neuron (SMN) protein and at least eight additional integral components, including the Gemin2-8 and unrip proteins; additional proteins, including galectin-1 and galectin-3, are also found in the SMN-SM complex. The SMN-Sm complex is involved in spliceosomal snRNP assembly in the cytoplasm.


go_id: GO:0034720
term: histone H3-K4 demethylation
ontology: BP
definition:
The modification of histone H3 by the removal of a methyl group from lysine at position 4 of the histone.


go_id: GO:0034721
term: histone H3-K4 demethylation, trimethyl-H3-K4-specific
ontology: BP
definition:
The modification of histone H3 by the removal of a methyl group from a trimetylated lysine at position 4 of the histone.


go_id: GO:0034728
term: nucleosome organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of one or more nucleosomes.


go_id: GO:0034729
term: histone H3-K79 methylation
ontology: BP
definition:
The modification of histone H3 by addition of a methyl group to lysine at position 79 of the histone.


go_id: GO:0034730
term: SmD-containing SMN-Sm protein complex
ontology: CC
definition:
An SMN-Sm protein complex formed by the association of the methylated Sm proteins B/B', D1, D2, D3, E, F, and G with the SMN complex.


go_id: GO:0034731
term: Lsm-containing SMN-Sm protein complex
ontology: CC
definition:
An SMN-Sm protein complex formed by the association of the methylated Sm proteins B/B', D3, E, F, and G, and Lsm10 and Lsm11, with the SMN complex. This complex forms Sm cores on U7 snRNA.


go_id: GO:0034732
term: transcription factor TFIIIB-alpha complex
ontology: CC
definition:
A transcription factor TFIIIB-beta complex that contains the TATA-binding protein (TBP), B'' and a specialized homolog of the conserved subunit BRF referred to as BRFU or TFIIIB50, which found in human but not conserved in yeast; the complex is involved in the regulation of transcription from type 3 (upstream) RNA polymerase III promoters.


go_id: GO:0034733
term: transcription factor TFIIIB-beta complex
ontology: CC
definition:
A transcription factor TFIIIB-beta complex that contains the TATA-binding protein (TBP), B'' and BRF, and is involved in the regulation of transcription from type 2 RNA polymerase III promoters.


go_id: GO:0034734
term: transcription factor TFIIIC1 complex
ontology: CC
definition:
A transcription factor complex that forms part of the TFIIIC complex, observed in human. The complex is poorly characterized, but contains the 250-kDa form of HsBdp1, and is thought to include nuclear factor 1 (NF1). It stimulates binding by human TFIIIC2 and is required for transcription activity.


go_id: GO:0034735
term: transcription factor TFIIIC2 complex
ontology: CC
definition:
A transcription factor complex that forms part of the TFIIIC complex, observed in human; composed of five subunits (GTF3C1/hTFIIIC220/TFIIICalpha, GTF3C2/hTFIIIC110/TFIIICbeta, GTF3C3/hTFIIIC102/TFIIICgamma, GTF3C4/hTFIIIC90/TFIIICdelta and GTF3C5/hTFIIIC63/TFIIICepsilon in human) that together recognize the type 2 RNA polymerase III promoter.


go_id: GO:0034739
term: histone deacetylase activity (H4-K16 specific)
ontology: MF
definition:
Catalysis of the reaction: histone H4 N6-acetyl-L-lysine (position 16) + H2O = histone H4 L-lysine (position 16) + acetate. This reaction represents the removal of an acetyl group from lysine at position 16 of the histone H4 protein.


go_id: GO:0034740
term: TFIIIC-TOP1-SUB1 complex
ontology: CC
definition:
A protein complex that contains TFIIIC, topoisomerase 1, and Sub1/PC4. Characterized in human, the complex is involved in regulating transcription from RNA polymerase III (Pol III) promoters. Topoisomerase 1 and Sub1 enhance the accuracy of transcription termination, and promote reinitiation by Pol III.


go_id: GO:0034741
term: APC-tubulin-IQGAP1 complex
ontology: CC
definition:
A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), alpha-tubulin, gamma-tubulin, and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization.


go_id: GO:0034743
term: APC-IQGAP complex
ontology: CC
definition:
A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC) and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization and cell migration.


go_id: GO:0034744
term: APC-IQGAP1-Cdc42 complex
ontology: CC
definition:
A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), the small GTPase Cdc42, and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization and cell migration.


go_id: GO:0034745
term: APC-IQGAP1-Rac1 complex
ontology: CC
definition:
A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), the small GTPase Rac1, and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization and cell migration.


go_id: GO:0034746
term: APC-IQGAP1-CLIP-170 complex
ontology: CC
definition:
A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), the small GTPase Cdc42, and CLIP-170; may play a role in cytoskeleton organization and cell migration.


go_id: GO:0034748
term: Par3-APC-KIF3A complex
ontology: CC
definition:
A protein complex that contains Par3, the tumor suppressor protein adenomatous polyposis coli (APC), and the kinesin-related protein KIF3A; involved in establishing neuronal cell polarity.


go_id: GO:0034749
term: Scrib-APC complex
ontology: CC
definition:
A protein complex that contains the Scribble protein (a cell polarity determinant) and the tumor suppressor protein adenomatous polyposis coli (APC); may be involved in the control of cell proliferation.


go_id: GO:0034750
term: Scrib-APC-beta-catenin complex
ontology: CC
definition:
A protein complex that contains the Scribble protein (a cell polarity determinant), the tumor suppressor protein adenomatous polyposis coli (APC), and beta-catenin; may be involved in the control of cell proliferation.


go_id: GO:0034751
term: aryl hydrocarbon receptor complex
ontology: CC
definition:
A protein complex that acts as an aryl hydrocarbon (Ah) receptor. Cytosolic and nuclear Ah receptor complexes have different subunit composition, but both contain the ligand-binding subunit AhR.


go_id: GO:0034752
term: cytosolic aryl hydrocarbon receptor complex
ontology: CC
definition:
An aryl hydrocarbon receptor complex found in the cytosol, in which the ligand-binding subunit AhR is not bound to ligand; consists of AhR, two molecules of HSP90, the protein kinase c-Src, and the immunophilin XAP2/AIP.


go_id: GO:0034753
term: nuclear aryl hydrocarbon receptor complex
ontology: CC
definition:
An aryl hydrocarbon receptor (AhR) complex found in the nucleus; ; consists of ligand-bound AhR and the aryl hydrocarbon receptor nuclear translocator (ARNT).


go_id: GO:0034754
term: cellular hormone metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone, as carried out by individual cells.


go_id: GO:0034755
term: iron ion transmembrane transport
ontology: BP
definition:
A process in which an iron ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.


go_id: GO:0034756
term: regulation of iron ion transport
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0034757
term: negative regulation of iron ion transport
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of iron ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0034758
term: positive regulation of iron ion transport
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the directed movement of iron ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0034759
term: regulation of iron ion transmembrane transport
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) from one side of a membrane to the other by means of some agent such as a transporter or pore.


go_id: GO:0034760
term: negative regulation of iron ion transmembrane transport
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of iron ions from one side of a membrane to the other by means of some agent such as a transporter or pore.


go_id: GO:0034761
term: positive regulation of iron ion transmembrane transport
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the directed movement of iron ions from one side of a membrane to the other by means of some agent such as a transporter or pore.


go_id: GO:0034762
term: regulation of transmembrane transport
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.


go_id: GO:0034763
term: negative regulation of transmembrane transport
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.


go_id: GO:0034764
term: positive regulation of transmembrane transport
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.


go_id: GO:0034765
term: regulation of ion transmembrane transport
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.


go_id: GO:0034766
term: negative regulation of ion transmembrane transport
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.


go_id: GO:0034767
term: positive regulation of ion transmembrane transport
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.


go_id: GO:0034769
term: basement membrane disassembly
ontology: BP
definition:
The controlled breakdown of the basement membrane in the context of a normal process such as imaginal disc eversion.


go_id: GO:0034770
term: histone H4-K20 methylation
ontology: BP
definition:
The modification of histone H4 by addition of one or more methyl groups to lysine at position 20 of the histone.


go_id: GO:0034771
term: histone H4-K20 monomethylation
ontology: BP
definition:
The modification of histone H4 by addition of one methyl group to lysine at position 20 of the histone.


go_id: GO:0034772
term: histone H4-K20 dimethylation
ontology: BP
definition:
The modification of histone H4 by addition of two methyl groups to lysine at position 20 of the histone.


go_id: GO:0034773
term: histone H4-K20 trimethylation
ontology: BP
definition:
The modification of histone H4 by addition of three methyl groups to lysine at position 20 of the histone.


go_id: GO:0034776
term: response to histamine
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.


go_id: GO:0034778
term: 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA = 4-isopropenyl-2-ketocyclohexane-1-carboxyl-CoA + 2 H+ + 2 e-.


go_id: GO:0034779
term: 4-isopropenyl-2-ketocyclohexane-1-carboxyl-CoA hydrolase activity
ontology: MF
definition:
Catalysis of the reaction: 4-isopropenyl-2-ketocyclohexane-1-carboxyl-CoA + H2O = 3-isopropenylpimelyl-CoA.


go_id: GO:0034787
term: 1-hydro-1,1a-dihydroxy-9-fluorenone dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 1-hydro-1,1a-dihydroxy-9-fluorenone + H2O = 2,3-dihydroxy-2'-carboxybiphenyl + 3 H+ + 2 e-.


go_id: GO:0034788
term: 2,3-dihydroxy-2'-carboxybiphenyl 1,2-dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 2,3-dihydroxy-2'-carboxybiphenyl + O2 = 2-hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate + H+.


go_id: GO:0034789
term: 2-hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate hydrolase activity
ontology: MF
definition:
Catalysis of the reaction: 2-hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate + H2O = cis-2-hydroxypenta-2,4-dienoate + phthalate + H+.


go_id: GO:0034790
term: 3,4-dihydroxy-3,4-dihydrofluorene dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: (+)-(3S,4R)-cis-3,4-dihydroxy-3,4-dihydrofluorene = 3,4-dihydroxyfluorene + 2 H+ + 2 e-.


go_id: GO:0034797
term: fosfomycin 2-glutathione ligase activity
ontology: MF
definition:
Catalysis of the reaction: hydrogen (2R,3S)-3-methyloxiran-2-ylphosphonic acid + glutathione = hydrogen (1R,2R)-1-glutathio-2-hydroxypropylphosphonic acid.


go_id: GO:0034798
term: fosfomycin 2-L-cysteine ligase activity
ontology: MF
definition:
Catalysis of the reaction: hydrogen (2R,3S)-3-methyloxiran-2-ylphosphonic acid + L-cysteine = hydrogen (1R,2R)-1-L-cysteine-2-hydroxypropylphosphonic acid.


go_id: GO:0034799
term: dihydride TNP tautomerase activity
ontology: MF
definition:
Catalysis of the reaction: TNP dihydride Meisenheimer complex (aci form) = TNP dihydride Meisenheimer complex (nitro form).


go_id: GO:0034800
term: trinitrophenol dihydride denitratase activity
ontology: MF
definition:
Catalysis of the reaction: trinitrophenol dihydride Meisenheimer complex (aci form) = 2,4-dinitrophenol hydride Meisenheimer complex + NO2. Trinitrophenol is also known as TNP and dinitrophenol is also known as DNP.


go_id: GO:0034802
term: branched-chain dodecylbenzene sulfonate monooxygenase activity
ontology: MF
definition:
Catalysis of the reaction: branched-chain dodecylbenzene sulfonate + 1/2 O2 + H+ = sulfurous acid + branched-chain dodecyl-4-hydroxy-benzene + sulfite.


go_id: GO:0034803
term: 3-hydroxy-2-naphthoate 2,3-dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 3-hydroxy-2-naphthoate + O2 = (3E)-3-[(6Z)-6-(carboxymethylene)cyclohexa-2,4-dien-1-ylidene]-2-oxopropanate.


go_id: GO:0034805
term: benzo(a)pyrene-trans-11,12-dihydrodiol dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: benzo(a)pyrene-trans-11,12-dihydrodiol = 11,12-dihydroxybenzo(a)pyrene + 2 H+ + 2 e-.


go_id: GO:0034812
term: 9,10-dihydroxybenzo(a)pyrene dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 9,10-dihydroxybenzo(a)pyrene + O2 = cis-4-(8-hydroxypyren-7-yl)-2-oxobut-3-enoate.


go_id: GO:0034814
term: 7,8-dihydroxy benzo(a)pyrene dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: benzo(a)pyrene-cis-7,8-dihydrodiol + O2 = cis-4-(7-hydroxypyren-8-yl)-2-oxobut-3-enoate.


go_id: GO:0034815
term: cis-4-(8-hydroxypyren-7-yl)-2-oxobut-3-enoate lyase activity
ontology: MF
definition:
Catalysis of the reaction: cis-4-(8-hydroxypyren-7-yl)-2-oxobut-3-enoate = 10-oxabenzo(def)chrysen-9-one + formate + H+.


go_id: GO:0034818
term: ADD 9alpha-hydroxylase activity
ontology: MF
definition:
Catalysis of the reaction: androsta-1,4-diene-3,17-dione + reduced ferredoxin + O2 = 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + H2O + oxidized ferredoxin.


go_id: GO:0034819
term: 3-HSA hydroxylase activity
ontology: MF
definition:
Catalysis of the reaction: 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + NADPH + H+ + O2 = 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + NADP+ + H2O.


go_id: GO:0034820
term: 4,9-DSHA hydrolase activity
ontology: MF
definition:
Catalysis of the reaction: (3E,1Z)-4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate + H2O = (2E,4E)-2-hydroxyhexa-2,4-dienoate + 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oate + H+.


go_id: GO:0034825
term: tetralin ring-hydroxylating dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: tetralin + O2 + NADH + H+ = cis-1,2-dihydroxy-1,2,5,6,7,8-hexahydronaphthalene + NAD+.


go_id: GO:0034826
term: 1,2-dihydroxy-1,2,5,6,7,8-hexyhadronaphthalene dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: cis-1,2-dihydroxy-1,2,5,6,7,8-hexahydronaphthalene + NAD+ = 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene + NADH + H+.


go_id: GO:0034827
term: 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene extradiol dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene + O2 = 4-(2-oxocyclohexyl)-2-hydroxy-buta-2,4-dienoate + H+.


go_id: GO:0034828
term: 4-(2-oxocyclohexyl)-2-hydroxy-buta-2,4-dienoate hydrolase activity
ontology: MF
definition:
Catalysis of the reaction: 4-(2-oxocyclohexyl)-2-hydroxy-buta-2,4-dienoate + H2O = 2-hydroxydec-2,4-diene-1,10-dioate + H+.


go_id: GO:0034829
term: 2-hydroxydec-2,4-diene-1,10-dioate hydratase activity
ontology: MF
definition:
Catalysis of the reaction: 2-hydroxydec-2,4-diene-1,10-dioate + H2O = (2Z)-2,4-dihydroxydec-2-enedioate.


go_id: GO:0034831
term: (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: (R)-1,2,3,4-tetrahydronaphthol = 1,2,3,4-tetrahydronaphthalone + 2 H+ + 2 e-.


go_id: GO:0034834
term: 2-mercaptobenzothiazole dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 2-mercaptobenzothiazole + O2 + 2 H+ + 2 e- = 2-mercaptobenzothiazole-cis-6,7-dihydrodiol.


go_id: GO:0034836
term: 6-hydroxy-2-mercaptobenzothiazole monooxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 6-hydroxy-2-mercaptobenzothiazole + 1/2 O2 = 6,7-dihydroxy-2-mercaptobenzothiazole.


go_id: GO:0034837
term: 2-mercaptobenzothiazole-cis-6,7-dihydrodiol dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 2-mercaptobenzothiazole-cis-6,7-dihydrodiol = 6,7-dihydroxy-2-mercaptobenzothiazole + 2 H+ + 2 e-.


go_id: GO:0034842
term: thiophene-2-carboxylate-CoA ligase activity
ontology: MF
definition:
Catalysis of the reaction: thiophene-2-carboxylate + ATP + CoASH = thiophene-2-carboxyl-CoA + AMP + PPi.


go_id: GO:0034844
term: naphthyl-2-methyl-succinate CoA-transferase activity
ontology: MF
definition:
Catalysis of the reaction: naphthyl-2-methyl-succinate + succinyl-CoA = naphthyl-2-methyl-succinyl-CoA + succinate.


go_id: GO:0034845
term: naphthyl-2-methyl-succinyl-CoA dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: naphthyl-2-methyl-succinyl-CoA = naphthyl-2-methylene-succinyl-CoA + 2 H+ + 2 e-.


go_id: GO:0034846
term: naphthyl-2-methylene-succinyl-CoA lyase activity
ontology: MF
definition:
Catalysis of the reaction: naphthyl-2-methylene-succinyl-CoA + H2O = naphthyl-2-hydroxymethyl-succinyl-CoA.


go_id: GO:0034847
term: naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: naphthyl-2-hydroxymethyl-succinyl-CoA = naphthyl-2-oxomethyl-succinyl-CoA + 2 H+ + 2 e-.


go_id: GO:0034848
term: naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity
ontology: MF
definition:
Catalysis of the reaction: naphthyl-2-oxomethyl-succinyl-CoA + CoASH = 2-naphthoyl-CoA + succinyl-CoA.


go_id: GO:0034851
term: 2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity
ontology: MF
definition:
Catalysis of the reaction: 2,4,4-trimethyl-3-oxopentanoyl-CoA + CoASH = pivalyl-CoA + propanoyl-CoA.


go_id: GO:0034852
term: 4,4-dimethyl-3-oxopentanal dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 4,4-dimethyl-3-oxopentanal + H2O = 4,4-dimethyl-3-oxopentanoate + 3 H+ + 2 e-.


go_id: GO:0034855
term: 4-AD 9alpha-hydroxylase activity
ontology: MF
definition:
Catalysis of the reaction: androst-4-ene-3,17-dione + O2 + 2 H+ + 2 e- = 9alpha-hydroxy-4-androstene-3,17-dione + H2O.


go_id: GO:0034860
term: 2-mercaptobenzothiazole desulfurase activity
ontology: MF
definition:
Catalysis of the reaction: 2-mercaptobenzothiazole + reduced acceptor = benzothiazole + hydrogen sulfide + oxidized acceptor.


go_id: GO:0034866
term: 2,4,4-trimethylpentanoyl-CoA dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 2,4,4-trimethylpentanoyl-CoA = 2,4,4-trimethylpent-2-enoyl-CoA + 2 H+ + 2 e-.


go_id: GO:0034867
term: 2,4,4-trimethylpent-2-enoyl-CoA hydratase activity
ontology: MF
definition:
Catalysis of the reaction: 2,4,4-trimethylpent-2-enoyl-CoA + H2O = 2,4,4-trimethyl-3-hydroxypentanoyl-CoA.


go_id: GO:0034868
term: 2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 2,4,4-trimethyl-3-hydroxypentanoyl-CoA = 2,4,4-trimethyl-3-oxopentanoyl-CoA + 2 H+ + 2 e-.


go_id: GO:0034869
term: 2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity
ontology: MF
definition:
Catalysis of the reaction: 2,4,4-trimethyl-3-oxopentanoyl-CoA + OH- = 2,4,4-trimethyl-3-oxopentanoate + CoASH.


go_id: GO:0034871
term: 1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 1-hydroxy-4,4-dimethylpentan-3-one = 4,4-dimethyl-3-oxopentanal + 2 H+ + 2 e-.


go_id: GO:0034874
term: thioacetamide S-oxide S-oxygenase activity
ontology: MF
definition:
Catalysis of the reaction: thioacetamide S-oxide + O2 + 2 H+ + 2 e- = thioacetamide S,S-dioxide + H2O.


go_id: GO:0034877
term: isonicotinate dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: isonicotinate + acceptor + H2O = 2-hydroxyisonicotinate + reduced acceptor.


go_id: GO:0034878
term: 2-hydroxyisonicotinate dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 2-hydroxyisonicotinate + acceptor + H2O = citrazinate + reduced acceptor.


go_id: GO:0034893
term: N-nitrodimethylamine hydroxylase activity
ontology: MF
definition:
Catalysis of the reaction: N-nitrodimethylamine + O2 + 2 H+ + 2 e- = N-nitromethylamine + formaldehyde + H2O.


go_id: GO:0034897
term: 4-(1-ethyl-1,4-dimethyl-pentyl)phenol monooxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 4-(1-ethyl-1,4-dimethyl-pentyl)phenol + O2 + 2 H+ + 2 e- = hydroquinone + 3,6-dimethylheptan-3-ol.


go_id: GO:0034898
term: hexadecyltrimethylammonium chloride monooxygenase activity
ontology: MF
definition:
Catalysis of the reaction: hexadecyltrimethylammonium chloride + NAD(P)H + H+ + O2 = trimethylamine + hexadecanal + NAD(P)+ + H2O.


go_id: GO:0034899
term: trimethylamine monooxygenase activity
ontology: MF
definition:
Catalysis of the reaction: N,N,N-trimethylamine + NADPH + H+ + O2 = N,N,N-trimethylamine N-oxide + NADP+ + H2O.


go_id: GO:0034906
term: N-isopropylaniline 1,2-dixoxygenase activity
ontology: MF
definition:
Catalysis of the reaction: N-isopropylaniline + O2 + 2 H+ + NADH = catechol + NAD+ + isopropylamine.


go_id: GO:0034908
term: 2-chloro-N-isopropylacetanilide 1,2-dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 2-chloro-N-isopropylacetanilide + O2 + 2 H+ + NADH = 2-chloro-N-isopropylacetamide + catechol + NAD+.


go_id: GO:0034909
term: 6-hydroxypseudooxynicotine dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 6-hydroxypseudooxynicotine + H2O + OH- = 6-hydroxy-3-succinoylpyridine + 4 H+ + 4 e- + methylamine.


go_id: GO:0034910
term: 6-hydroxy-3-succinoylpyridine hydrolase activity
ontology: MF
definition:
Catalysis of the reaction: 6-hydroxy-3-succinoylpyridine + H2O = succinic semialdehyde + 2,5-dihydroxypyridine.


go_id: GO:0034912
term: phthalate 3,4-cis-dihydrodiol dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: phthalate 3,4-cis-dihydrodiol + NAD+ = 3,4-dihydroxyphthalate + NADH + H+.


go_id: GO:0034914
term: trinitrophenol hydride denitratase activity
ontology: MF
definition:
Catalysis of the reaction: trinitrophenol hydride Meisenheimer complex = 2,4-dinitrophenol + nitrite. Trinitrophenol is also known as TNP.


go_id: GO:0034918
term: 3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 3-hydroxy-2-methylhexanoyl-CoA = 2-methyl-3-oxohexanoyl-CoA + 2 H+ + 2 e-.


go_id: GO:0034924
term: cis-3,4-phenanthrenedihydrodiol-4-carboxylate dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: cis-3,4-phenanthrenedihydrodiol-4-carboxylate = 3,4-dihydroxyphenanthrene + H+ + 2 e- + CO2.


go_id: GO:0034934
term: phenanthrene-4-carboxylate dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: phenanthrene-4-carboxylate + 2 H+ + 2 e- + O2 = cis-3,4-phenanthrenedihydrodiol-4-carboxylate.


go_id: GO:0034935
term: tetrachlorobenzene dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 2,4-dichlorotoluene + NADH + H+ + O2 = 4,6-dichloro-3-methyl-cis-1,2-dihydroxycyclohexa-3,5-diene + NAD+.


go_id: GO:0034936
term: 4,6-dichloro-3-methylcatechol 1,2-dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 4,6-dichloro-3-methylcatechol + O2 = 3,5-dichloro-3-methyl-cis,cis-muconate + 2 H+.


go_id: GO:0034938
term: pyrrole-2-carboxylate monooxygenase activity
ontology: MF
definition:
Catalysis of the reaction: pryrole-2-carboxylate + NADH + O2 + H+ = 5-hydroxypyrrole-2-carboxylate + NAD+ + H2O.


go_id: GO:0034942
term: cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity
ontology: MF
definition:
Catalysis of the reaction: cis-2-methyl-5-isopropylhexa-2,5-dienoic acid + ATP + CoASH = cis-2-methyl-5-isopropylhexa-2,5-dienoyl-CoA + AMP + PPi.


go_id: GO:0034943
term: trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity
ontology: MF
definition:
Catalysis of the reaction: trans-2-methyl-5-isopropylhexa-2,5-dienoic acid + ATP + CoASH = trans-2-methyl-5-isopropylhexa-2,5-dienoyl-CoA + AMP + PPi.


go_id: GO:0034944
term: 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA + NAD+ = 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA + NADH+ + H+.


go_id: GO:0034945
term: 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA + CoASH = 3-isopropylbut-3-enoyl-CoA + propanoyl-CoA.


go_id: GO:0034948
term: 2,6-dihydroxypseudooxynicotine hydrolase activity
ontology: MF
definition:
Catalysis of the reaction: 2,6-dihydroxypseudooxynicotine + H2O = 2,6-dihydroxypyridine + 4-methylaminobutyrate.


go_id: GO:0034959
term: endothelin maturation
ontology: BP
definition:
The process leading to the attainment of the full functional capacity of endothelin by conversion of Big-endothelin substrate into mature endothelin.


go_id: GO:0034963
term: box C/D RNA processing
ontology: BP
definition:
Any process involved in the conversion of a primary box C/D type small  RNA transcript into a mature box C/D RNA.


go_id: GO:0034964
term: box H/ACA RNA processing
ontology: BP
definition:
Any process involved in the conversion of a primary box H/ACA type small  RNA transcript into a mature box H/ACA RNA.


go_id: GO:0034965
term: intronic box C/D RNA processing
ontology: BP
definition:
Any process involved in the conversion of a primary box C/D type small nucleolar RNA (snoRNA) transcript that resides within, and is processed from, the intron of a pre-mRNA into a mature box C/D snoRNA.


go_id: GO:0034966
term: intronic box H/ACA snoRNA processing
ontology: BP
definition:
Any process involved in the conversion of a primary box H/ACA type small nucleolar RNA (snoRNA) transcript that resides within, and is processed from, the intron of a pre-mRNA into a mature box H/ACA snoRNA.


go_id: GO:0034967
term: Set3 complex
ontology: CC
definition:
A histone deacetylase complex that is involved in transcriptional regulation. In S. cerevisiae, this complex consists of Set3p, Snt1p, Hos4p, Sif2p, Cpr1p, Hos2p, and Hst1p.


go_id: GO:0034970
term: histone H3-R2 methylation
ontology: BP
definition:
The modification of histone H3 by addition of a methyl group to arginine at position 2 of the histone.


go_id: GO:0034971
term: histone H3-R17 methylation
ontology: BP
definition:
The modification of histone H3 by addition of a methyl group to arginine at position 17 of the histone.


go_id: GO:0034972
term: histone H3-R26 methylation
ontology: BP
definition:
The modification of histone H3 by addition of a methyl group to arginine at position 26 of the histone.


go_id: GO:0034973
term: Sid2-Mob1 complex
ontology: CC
definition:
A protein complex that contains a protein kinase (Sid2 in S. pombe) and its regulatory subunit (Mob1). The Sid2p-Mob1p kinase complex is a component of the septation initiation network in fission yeast (called the mitotic exit network in S. cerevisiae) and is required for cytokinesis. The analogous complex in S. cerevisiae is called Dbf2p-Mob1p complex.


go_id: GO:0034974
term: Swi5-Swi2 complex
ontology: CC
definition:
A protein complex involved that contains proteins known in Schizosaccharomyces as Swi5 monomers and Swi2, and is involved in mating type switching.


go_id: GO:0034975
term: protein folding in endoplasmic reticulum
ontology: BP
definition:
A protein folding process that takes place in the endoplasmic reticulum (ER). Secreted, plasma membrane and organelle proteins are folded in the ER, assisted by chaperones and foldases (protein disulphide isomerases), and additional factors required for optimal folding (ATP, Ca2+ and an oxidizing environment to allow disulfide bond formation).


go_id: GO:0034976
term: response to endoplasmic reticulum stress
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.


go_id: GO:0034977
term: ABIN2-NFKB1-MAP3K8 complex
ontology: CC
definition:
A protein complex that contains the precursor form of NF-kappaB (p105), the NF-kappaB inhibitor ABIN-2, and the kinase TPL-2 (MAP3K8); the complex stabilizes TPL-2 and is involved in signaling in lipopolysaccharide (LPS)-stimulated macrophages.


go_id: GO:0034978
term: PDX1-PBX1b-MRG1 complex
ontology: CC
definition:
A protein complex that contains the homeodomain proteins PDX1, PBX1b and MRG1 (MEIS2) and is involved in the transcriptional regulation of pancreatic acinar cell-specific genes.


go_id: GO:0034985
term: Ecsit-NDUFAF1 complex
ontology: CC
definition:
Any large protein complex that contains Ecsit and NDUFAF1, is located in the mitochondrion, and is involved in the assembly of complex I of the oxidative phosphorylation system. In mammalian cells, three complexes of approximately 500, 600, and 850 kDa containing the 45 kDa isoform of Ecsit and NDUFAF1 have been observed.


go_id: GO:0034988
term: Fc-gamma receptor I complex binding
ontology: MF
definition:
Binding to one or more specific sites on the Fc-gamma receptor I complex. The complex functions primarily as an activating receptor for IgG.


go_id: GO:0034992
term: microtubule organizing center attachment site
ontology: CC
definition:
A region of the nuclear envelope to which a microtubule organizing center (MTOC) attaches; protein complexes embedded in the nuclear envelope mediate direct or indirect linkages between the microtubule cytoskeleton and the nuclear envelope.


go_id: GO:0034993
term: meiotic nuclear membrane microtubule tethering complex
ontology: CC
definition:
A nuclear membrane  protein complex  which connects the nuclear outer and inner membranes together, and links links the nuclear lumen to cytoplasmic microtubules during meiosis.


go_id: GO:0034994
term: microtubule organizing center attachment site organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microtubule organizing center attachment site. A microtubule organizing center attachment site is a region of the nuclear envelope to which a microtubule organizing center (MTOC) attaches.


go_id: GO:0034995
term: SC5b-7 complex
ontology: CC
definition:
A protein complex that consist of complement components C5b6 and C7 stably inserted in a cell membrane. Formation of the SC5b-7 complex is the first phase of membrane attack complex assembly.


go_id: GO:0034996
term: RasGAP-Fyn-Lyn-Yes complex
ontology: CC
definition:
A protein complex that consists of a GTPase activator protein (GAP) for Ras and three Src family protein tyrosine kinases, Fyn, Lyn and Yes. The complex is involved in signaling upon platelet activation.


go_id: GO:0034997
term: alphav-beta5 integrin-vitronectin complex
ontology: CC
definition:
A protein complex that comprises one integrin alphav subunit, one integrin beta5 subunit, and vitronectin.


go_id: GO:0034998
term: oligosaccharyltransferase I complex
ontology: CC
definition:
An oligosaccharyltransferase (OST) complex that contains at least seven polypeptides and is the major OST complex in mammalian cells. Of the three forms of mammalian OST complex identified, the OSTI complex has the weakest affinity for ribosomes.


go_id: GO:0034999
term: oligosaccharyltransferase II complex
ontology: CC
definition:
An oligosaccharyltransferase (OST) complex that contains the seven polypeptides found in OST complex I, plus heterotrimeric Sec61alpha-beta-gamma. Of the three forms of mammalian OST complexes identified, the OSTII complex has intermediate affinity for ribosomes.


go_id: GO:0035000
term: oligosaccharyltransferase III complex
ontology: CC
definition:
An oligosaccharyltransferase (OST) complex that contains the seven polypeptides found in OST complex I, plus heterotrimeric Sec61alpha-beta-gamma and the tetrameric TRAP complex. Of the three forms of mammalian OST complexes identified, the OSTIII complex has the strongest affinity for ribosomes.


go_id: GO:0035001
term: dorsal trunk growth, open tracheal system
ontology: BP
definition:
Growth of epithelial tubes that originate from pits in an open tracheal system and grow towards each other to meet and form a continuous open tube called the dorsal trunk. The dorsal trunk extends from the anterior spiracle to the posterior spiracle of the larva and forms the main airway of the insect tracheal system.


go_id: GO:0035002
term: liquid clearance, open tracheal system
ontology: BP
definition:
The clearance of liquid from the epithelial tubes of an open tracheal system, shortly before the emergence of the larva, to generate an air-filled tubule system.


go_id: GO:0035003
term: subapical complex
ontology: CC
definition:
The most apical region of the lateral plasma membrane of an invertebrate epithelial cell. The subapical complex lies above the zonula adherens and the septate junction, and is comparable to the position of the tight junction of vertebrate cells.


go_id: GO:0035004
term: phosphatidylinositol 3-kinase activity
ontology: MF
definition:
Catalysis of the reaction: ATP + a phosphatidylinositol = ADP + a phosphatidylinositol 3-phosphate. This reaction is the addition of a phosphate group to phosphatidylinositol or one of its phosphorylated derivatives at the 3' position of the inositol ring.


go_id: GO:0035005
term: 1-phosphatidylinositol-4-phosphate 3-kinase activity
ontology: MF
definition:
Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4-phosphate + ATP = 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + ADP + 2 H(+).


go_id: GO:0035006
term: melanization defense response
ontology: BP
definition:
The blackening of the wounded area of the cuticle or the surface of invading pathogens, parasites or parasitoids, resulting from a proteolytic cascade leading to the de novo synthesis and deposition of melanin.


go_id: GO:0035007
term: regulation of melanization defense response
ontology: BP
definition:
Any process that affects the rate, extent or location of the melanization defense response during injury or invasion.


go_id: GO:0035008
term: positive regulation of melanization defense response
ontology: BP
definition:
Any process that increases the rate or extent of the melanization defense response during injury or invasion.


go_id: GO:0035009
term: negative regulation of melanization defense response
ontology: BP
definition:
Any process that reduces the rate or extent of the melanization defense response. This regulation is critical to limit melanization to the site of injury or infection.


go_id: GO:0035010
term: encapsulation of foreign target
ontology: BP
definition:
Events resulting in the formation of a multilayered cellular sheath surrounding an invader and thus preventing its development. This defense mechanism is often seen in insects in response to nematodes or parasitoids, which are too large to be phagocytosed by individual hemocytes. In some organisms the capsule is blackened due to melanization.


go_id: GO:0035014
term: phosphatidylinositol 3-kinase regulator activity
ontology: MF
definition:
Modulates the activity of any of the phosphatidylinositol 3-kinases (PI3Ks). Regulatory subunits can link a PI3K catalytic subunit to upstream signaling events and help position the catalytic subunits close to their lipid substrates.


go_id: GO:0035015
term: elongation of arista core
ontology: BP
definition:
The increase in length of the aristal core. The arista is the terminal segment of the antenna and consists of a central core and a series of lateral extensions.


go_id: GO:0035016
term: elongation of arista lateral
ontology: BP
definition:
The increase in length of the aristal laterals. The arista is the terminal segment of the antenna and consists of a central core and a series of lateral extensions.


go_id: GO:0035018
term: adult chitin-based cuticle pattern formation
ontology: BP
definition:
The process that gives rise to the patterns of cell differentiation that will arise in the chitin-based adult cuticle. An example of this process is adult chitin-based cuticle pattern formation in Drosophila melanogaster.


go_id: GO:0035019
term: somatic stem cell population maintenance
ontology: BP
definition:
Any process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line.


go_id: GO:0035021
term: negative regulation of Rac protein signal transduction
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of Rac protein signal transduction.


go_id: GO:0035022
term: positive regulation of Rac protein signal transduction
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of Rac protein signal transduction.


go_id: GO:0035024
term: negative regulation of Rho protein signal transduction
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of Rho protein signal transduction.


go_id: GO:0035025
term: positive regulation of Rho protein signal transduction
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of Rho protein signal transduction.


go_id: GO:0035026
term: leading edge cell differentiation
ontology: BP
definition:
The process in which relatively unspecialized cells acquire specialized structural and/or functional features of leading edge cells, cells at the front of a migrating epithelial sheet.


go_id: GO:0035027
term: leading edge cell fate commitment
ontology: BP
definition:
The commitment of cells to leading edge cell fate and their capacity to differentiate into leading edge cells. Leading edge cells are found at the front of a migrating epithelial sheet.


go_id: GO:0035028
term: leading edge cell fate determination
ontology: BP
definition:
The process in which a cell becomes capable of differentiating autonomously into a leading edge cell regardless of its environment; upon determination, the cell fate cannot be reversed.


go_id: GO:0035029
term: dorsal closure, leading edge cell fate commitment
ontology: BP
definition:
The commitment of cells to leading edge cell fate during dorsal closure. Leading edge cells are the dorsal-most cells of the migrating epidermis.


go_id: GO:0035032
term: phosphatidylinositol 3-kinase complex, class III
ontology: CC
definition:
A phosphatidylinositol 3-kinase complex that contains a catalytic class III phosphoinositide 3-kinase (PI3K) subunit bound to a regulatory (adaptor) subunit. Additional adaptor proteins may be present. Class III PI3Ks have a substrate specificity restricted to phosphatidylinositol (PI).


go_id: GO:0035036
term: sperm-egg recognition
ontology: BP
definition:
The initial contact step made between the sperm plasma membrane and outer layer of the egg during fertilization.


go_id: GO:0035037
term: sperm entry
ontology: BP
definition:
An endocytosis process that results in penetration of the egg shell through the micropyle (a specialized anterior opening in the vitelline envelope) and entry of the entire sperm, including the surrounding plasma membrane and the sperm tail, into the egg cytoplasm. This step in fertilization is seen in Drosophila, where a plasma membrane fusion event between the sperm and the egg does not occur.


go_id: GO:0035039
term: male pronucleus assembly
ontology: BP
definition:
The conversion at fertilization of the inactive sperm nucleus into a male pronucleus with its chromosomes processed for the first zygotic division.


go_id: GO:0035043
term: male pronuclear envelope synthesis
ontology: BP
definition:
Assembly of a nuclear envelope containing nuclear pores and a lamina around the male pronucleus, the final step in sperm pronuclear formation.


go_id: GO:0035044
term: sperm aster formation
ontology: BP
definition:
Formation and organization of an aster composed of microtubule arrays originating from the sperm basal body and extending virtually to the egg periphery. The sperm aster ensures the appropriate positioning of the male and female pronuclei.


go_id: GO:0035045
term: sperm plasma membrane disassembly
ontology: BP
definition:
The gradual disintegration of the sperm plasma membrane following insemination. This process is seen in Drosophila after entry of the entire sperm, surrounded by its plasma membrane, into the egg.


go_id: GO:0035047
term: centrosomal and pronuclear rotation
ontology: BP
definition:
The rotation of centrosomes and associated pronuclei in one-cell embryos such as those of Caenorhabditis elegans, occurring as a transition between pronuclear migration and pronuclear fusion.


go_id: GO:0035050
term: embryonic heart tube development
ontology: BP
definition:
The process whose specific outcome is the progression of the embryonic heart tube over time, from its formation to the mature structure. The heart tube forms as the heart rudiment from the heart field.


go_id: GO:0035051
term: cardiocyte differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell that will form part of the cardiac organ of an individual.


go_id: GO:0035052
term: dorsal vessel aortic cell fate commitment
ontology: BP
definition:
The commitment of dorsal vessel cardioblast cells to an aortic cell fate and their capacity to differentiate into aortic cells. An example of this process is found in Drosophila melanogaster.


go_id: GO:0035053
term: dorsal vessel heart proper cell fate commitment
ontology: BP
definition:
The commitment of dorsal vessel cardioblast cells to a heart proper cell fate and their capacity to differentiate into heart cells. An example of this process is found in Drosophila melanogaster.


go_id: GO:0035054
term: embryonic heart tube anterior/posterior pattern specification
ontology: BP
definition:
The establishment, maintenance and elaboration of cell differentiation that results in the anterior/posterior subdivision of the embryonic heart tube. In Drosophila this results in subdivision of the dorsal vessel into to the posterior heart proper and the anterior aorta.


go_id: GO:0035059
term: RCAF complex
ontology: CC
definition:
A protein complex that facilitates the assembly of nucleosomes on to newly synthesized DNA. In Drosophila, the complex comprises ASF1 and histones H3 and H4.


go_id: GO:0035060
term: brahma complex
ontology: CC
definition:
A SWI/SNF-type complex that contains 8 to 14 proteins, including both conserved (core) and nonconserved components; contains the ATPase product of the Drosophila brm (brahma) or mammalian SMARCA2/BAF190B/BRM gene, or an ortholog thereof.


go_id: GO:0035061
term: interchromatin granule
ontology: CC
definition:
A class of nuclear body measuring 20-25 nm in diameter and distributed throughout the interchromatin space, linked together by thin fibrils. They are believed to be storage centers for various snRNAs, snRNPs, serine/arginine-rich proteins and RNA polymerase II. A typical mammalian cell contains 25-50 clusters of interchromatin granules. Interchromatin granule clusters do not contain the heterogeneous nuclear RNA-binding proteins (hnRNPs).


go_id: GO:0035062
term: omega speckle
ontology: CC
definition:
A nucleoplasmic speckle distributed in the interchromatin space of cells in close proximity to chromatin. Omega speckles are distinct from interchromatin granules and contain heterogeneous nuclear RNA-binding proteins (hnRNPs).


go_id: GO:0035063
term: nuclear speck organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of nuclear specks, a class of nuclear body in which splicing factors are localized.


go_id: GO:0035065
term: regulation of histone acetylation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the addition of an acetyl group to a histone protein.


go_id: GO:0035066
term: positive regulation of histone acetylation
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the addition of an acetyl group to a histone protein.


go_id: GO:0035067
term: negative regulation of histone acetylation
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of an acetyl group to a histone protein.


go_id: GO:0035069
term: larval midgut histolysis
ontology: BP
definition:
The stage-specific break down of the larval midgut during Drosophila metamorphosis, to allow replacement of larval structures by tissues and structures that form the adult fly.


go_id: GO:0035070
term: salivary gland histolysis
ontology: BP
definition:
The stage-specific break down of the larval salivary glands during Drosophila metamorphosis, to allow replacement of larval structures by tissues and structures that form the adult fly.


go_id: GO:0035072
term: ecdysone-mediated induction of salivary gland cell autophagic cell death
ontology: BP
definition:
Any process induced by ecdysone that directly activates salivary gland programmed cell death during salivary gland histolysis.


go_id: GO:0035073
term: pupariation
ontology: BP
definition:
The onset of prepupal development when the larval stops crawling, everts its spiracles and the larval cuticle becomes the puparium or pupal case that surrounds the organism for the duration of metamorphosis.


go_id: GO:0035074
term: pupation
ontology: BP
definition:
The act of becoming a pupa, a resting stage in the life cycle of organisms with complete metamorphosis. This event marks the end of the prepupal period and the beginning of the pupal period.


go_id: GO:0035075
term: response to ecdysone
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ecdysone stimulus.


go_id: GO:0035077
term: ecdysone-mediated polytene chromosome puffing
ontology: BP
definition:
The decondensing (loosening) and swelling of the chromosomal sites of hormone-responsive genes on polytene chromosomes in response to increased production of the steroid hormone 20-hydroxyecdysone (ecdysone) in Drosophila larvae approaching pupation.


go_id: GO:0035078
term: induction of programmed cell death by ecdysone
ontology: BP
definition:
Any process induced by the steroid hormone 20-hydroxyecdysone (ecdysone) that directly activates any of the steps required for programmed cell death.


go_id: GO:0035079
term: polytene chromosome puffing
ontology: BP
definition:
The decondensing (loosening) and swelling of the chromosomal sites of target genes on polytene chromosomes following response to a stimulus, to facilitate sudden bursts of transcriptional activity in response to transient environmental signals.


go_id: GO:0035080
term: heat shock-mediated polytene chromosome puffing
ontology: BP
definition:
The decondensing (loosening) and swelling of the chromosomal sites of heat shock genes on polytene chromosomes in response to a heat shock stimulus.


go_id: GO:0035081
term: induction of programmed cell death by hormones
ontology: BP
definition:
Any process induced by hormones that directly activates any of the steps required for programmed cell death.


go_id: GO:0035082
term: axoneme assembly
ontology: BP
definition:
The assembly and organization of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.


go_id: GO:0035088
term: establishment or maintenance of apical/basal cell polarity
ontology: BP
definition:
Any cellular process that results in the specification, formation or maintenance polarization of a cell's architecture along its apical/basal axis so that the apical and basal regions of the cell have different membrane, extracellular matrix and sub-membrane cellular components.


go_id: GO:0035091
term: phosphatidylinositol binding
ontology: MF
definition:
Binding to an inositol-containing glycerophospholipid, i.e. phosphatidylinositol (PtdIns) and its phosphorylated derivatives.


go_id: GO:0035092
term: sperm DNA condensation
ontology: BP
definition:
The progressive compaction of the spermatid chromatin so that it reaches a level of condensation that is not compatible with nuclear activities such as transcription or DNA replication.


go_id: GO:0035094
term: response to nicotine
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus.


go_id: GO:0035095
term: behavioral response to nicotine
ontology: BP
definition:
Any process that results in a change in the behavior of an organism as a result of a nicotine stimulus.


go_id: GO:0035096
term: larval midgut cell programmed cell death
ontology: BP
definition:
The stage-specific programmed cell death of cells of the larval midgut, during histolysis of the larval organ.


go_id: GO:0035098
term: ESC/E(Z) complex
ontology: CC
definition:
A multimeric protein complex that can methylate lysine-27 and lysine-9 residues of histone H3. In Drosophila the core subunits of the complex include ESC, E(Z), CAF1 (NURF-55) and SU(Z)12. In mammals the core subunits of the complex include EED, EZH2, SUZ12 and RBBP4.


go_id: GO:0035099
term: hemocyte migration
ontology: BP
definition:
The directed movement of a hemocyte within the embryo. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. In Drosophila, embryonic hemocytes originate from the head mesoderm as a cluster of cells. The cluster splits into two and one group of cells crosses the amnioserosa. Both populations then spread toward the middle of the embryo and then disperse evenly throughout the embryo.


go_id: GO:0035100
term: ecdysone binding
ontology: MF
definition:
Binding to 20-hydroxyecdysone (ecdysone). Ecdysone is an ecdysteroid produced by the prothoracic glands of immature insects and the ovaries of adult females, which stimulates growth and molting.


go_id: GO:0035101
term: FACT complex
ontology: CC
definition:
A histone chaperone complex that facilitates nucleosome disassembly and reassembly upon DNA or RNA polymerase passage.


go_id: GO:0035102
term: PRC1 complex
ontology: CC
definition:
A multiprotein complex that mediates monoubiquitination of lysine residues of histone H2A (lysine-118 in Drosophila or lysine-119 in mammals). The complex is required for stable long-term maintenance of transcriptionally repressed states and is involved in chromatin remodeling.


go_id: GO:0035103
term: sterol regulatory element binding protein cleavage
ontology: BP
definition:
The proteolytic release of a transcriptionally active sterol regulatory element binding protein (SREBP) from intracellular membranes, freeing it to move to the nucleus to upregulate transcription of target genes, in response to altered levels of one or more lipids.


go_id: GO:0035106
term: operant conditioning
ontology: BP
definition:
Learning to anticipate future events on the basis of past experience with the consequences of one's own behavior.


go_id: GO:0035107
term: appendage morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch.


go_id: GO:0035108
term: limb morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of a limb are generated and organized. A limb is a paired appendage of a tetrapod used for locomotion or grasping.


go_id: GO:0035112
term: genitalia morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of genitalia are generated and organized. The genitalia are the organs of reproduction or generation, external and internal.


go_id: GO:0035113
term: embryonic appendage morphogenesis
ontology: BP
definition:
The process, occurring in the embryo, by which the anatomical structures of the appendage are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch.


go_id: GO:0035114
term: imaginal disc-derived appendage morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism.


go_id: GO:0035115
term: embryonic forelimb morphogenesis
ontology: BP
definition:
The process, occurring in the embryo, by which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human.


go_id: GO:0035116
term: embryonic hindlimb morphogenesis
ontology: BP
definition:
The process, occurring in the embryo, by which the anatomical structures of the hindlimbs are generated and organized. The hindlimbs are the posterior limbs of an animal.


go_id: GO:0035118
term: embryonic pectoral fin morphogenesis
ontology: BP
definition:
The process, occurring in the embryo, by which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion.


go_id: GO:0035119
term: embryonic pelvic fin morphogenesis
ontology: BP
definition:
The process, occurring in the embryo, by which the anatomical structures of the pelvic fin are generated and organized. The pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion.


go_id: GO:0035120
term: post-embryonic appendage morphogenesis
ontology: BP
definition:
The process, occurring after embryonic development, by which the anatomical structures of an appendage are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch.


go_id: GO:0035122
term: embryonic medial fin morphogenesis
ontology: BP
definition:
The process, occurring in the embryo, by which the anatomical structures of the medial fin are generated and organized. Medial fins are unpaired fins of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming.


go_id: GO:0035123
term: embryonic dorsal fin morphogenesis
ontology: BP
definition:
The process, occurring in the embryo, by which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of a fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins.


go_id: GO:0035124
term: embryonic caudal fin morphogenesis
ontology: BP
definition:
The process, occurring in the embryo, by which the anatomical structures of the caudal fin are generated and organized. The caudal fin is an unpaired medial fin mounted at the caudal end of the fish and is the main fin used for propulsion.


go_id: GO:0035125
term: embryonic anal fin morphogenesis
ontology: BP
definition:
The process, occurring in the embryo, by which the anatomical structures of the embryonic anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming.


go_id: GO:0035126
term: post-embryonic genitalia morphogenesis
ontology: BP
definition:
The process, occurring after embryonic development, by which the anatomical structures of the genitalia are generated and organized.


go_id: GO:0035127
term: post-embryonic limb morphogenesis
ontology: BP
definition:
The process, occurring after embryonic development, by which the anatomical structures of the limb are generated and organized. A limb is an appendage of an animal used for locomotion or grasping.


go_id: GO:0035128
term: post-embryonic forelimb morphogenesis
ontology: BP
definition:
The process, occurring after embryonic development, by which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an organism.


go_id: GO:0035129
term: post-embryonic hindlimb morphogenesis
ontology: BP
definition:
The process, occurring after embryonic development, by which the anatomical structures of the hindlimb are generated and organized.


go_id: GO:0035130
term: post-embryonic pectoral fin morphogenesis
ontology: BP
definition:
The process, occurring after embryonic development, by which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion.


go_id: GO:0035131
term: post-embryonic pelvic fin morphogenesis
ontology: BP
definition:
The process, occurring after embryonic development, by which the anatomical structures of the pelvic fin are generated and organized. The pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion.


go_id: GO:0035132
term: post-embryonic medial fin morphogenesis
ontology: BP
definition:
The process, occurring after embryonic development, by which the anatomical structures of the medial fin are generated and organized. Medial fins are unpaired fins of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming.


go_id: GO:0035133
term: post-embryonic caudal fin morphogenesis
ontology: BP
definition:
The process, occurring after embryonic development, by which the anatomical structures of the caudal fin are generated and organized. The caudal fin is an unpaired medial fin mounted at the caudal end of the fish and is the main fin used for propulsion.


go_id: GO:0035134
term: post-embryonic dorsal fin morphogenesis
ontology: BP
definition:
The process, occurring after embryonic development, by which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of a fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins.


go_id: GO:0035135
term: post-embryonic anal fin morphogenesis
ontology: BP
definition:
The process, occurring after embryonic development, by which the anatomical structures of the anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming.


go_id: GO:0035136
term: forelimb morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human.


go_id: GO:0035138
term: pectoral fin morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion.


go_id: GO:0035139
term: pelvic fin morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the pelvic fin are generated and organized. Pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion.


go_id: GO:0035141
term: medial fin morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the medial fin are generated and organized. A medial fin is an unpaired fin of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming.


go_id: GO:0035142
term: dorsal fin morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins.


go_id: GO:0035143
term: caudal fin morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the caudal fin are generated and organized. A caudal fin is an unpaired medial fin mounted at the caudal end of the fish, and is the main fin used for propulsion.


go_id: GO:0035144
term: anal fin morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming.


go_id: GO:0035145
term: exon-exon junction complex
ontology: CC
definition:
A multi-subunit complex deposited by the spliceosome upstream of messenger RNA exon-exon junctions. The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay.


go_id: GO:0035147
term: branch fusion, open tracheal system
ontology: BP
definition:
Fusing of specific tracheal branches in an open tracheal system to branches from neighboring hemisegments to form a continuous tracheal network. Branch fusion is mediated by individual cells at the tip of each branch, which contact a similar cell and undergo a coordinated series of morphogenetic events that create a bicellular fusion joint.


go_id: GO:0035148
term: tube formation
ontology: BP
definition:
Creation of the central hole of a tube in an anatomical structure through which gases and/or liquids flow.


go_id: GO:0035150
term: regulation of tube size
ontology: BP
definition:
Ensuring that a tube is of the correct length and diameter. Tube size must be maintained not only during tube formation, but also throughout development and in some physiological processes.


go_id: GO:0035151
term: regulation of tube size, open tracheal system
ontology: BP
definition:
Ensuring that an epithelial tube in an open tracheal system is of the correct length and diameter. Tracheal tubes undergo highly regulated tube-size increases during development, expanding up to 40 times their initial size by the end of larval life. Tube size appears to be controlled by regulation of apical membrane expansion and secretion, rather than by changes in cell number, size or shape.


go_id: GO:0035152
term: regulation of tube architecture, open tracheal system
ontology: BP
definition:
Ensuring that tracheal cells form and maintain tubular structures with the correct size and shape for their position in the network. This is essential for efficient flow of gases through the tracheal network.


go_id: GO:0035153
term: epithelial cell type specification, open tracheal system
ontology: BP
definition:
Allocation of epithelial cells within each migrating branch in an open tracheal system to distinct tracheal cell fates. During the migration phase each branch forms a well-defined number of cell types (including fusion cells, terminal cells and branch cells) at precise positions.


go_id: GO:0035154
term: terminal cell fate specification, open tracheal system
ontology: BP
definition:
The process in which a cell in an open tracheal system becomes capable of differentiating autonomously into a terminal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. Terminal cells send long and bifurcated hollow branches toward target tissues to allow oxygen exchange.


go_id: GO:0035155
term: negative regulation of terminal cell fate specification, open tracheal system
ontology: BP
definition:
Any process that restricts, stops or prevents a cell from adopting a terminal cell fate in an open tracheal system. Once the terminal and fusion fates have been correctly induced, inhibitory feedback loops prevent the remaining branch cells from assuming similar fates.


go_id: GO:0035156
term: fusion cell fate specification
ontology: BP
definition:
The process in which a cell becomes capable of differentiating autonomously into a fusion cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. Fusion cells allow the interconnection of adjacent tracheal metameres during tracheal tube fusion.


go_id: GO:0035157
term: negative regulation of fusion cell fate specification
ontology: BP
definition:
Any process that restricts, stops or prevents a cell from adopting a fusion cell fate. Once the terminal and fusion fates have been correctly induced, inhibitory feedback loops prevent the remaining branch cells from assuming similar fates.


go_id: GO:0035158
term: regulation of tube diameter, open tracheal system
ontology: BP
definition:
Ensuring that a tube in an open tracheal system is of the correct diameter. When primary branches form their lumens are small (less than 2 micrometers) in caliber and must undergo regulated expansion during larval life to reach their mature size.


go_id: GO:0035160
term: maintenance of epithelial integrity, open tracheal system
ontology: BP
definition:
Ensuring that tracheal tubes in an open tracheal system maintain their epithelial structure during the cell shape changes and movements that occur during the branching process.


go_id: GO:0035161
term: imaginal disc lineage restriction
ontology: BP
definition:
Formation and/or maintenance of a lineage boundary between compartments in an imaginal disc that cells cannot cross, thus separating the populations of cells in each compartment.


go_id: GO:0035163
term: embryonic hemocyte differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell derived from the embryonic head mesoderm acquires the specialized features of a mature hemocyte. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen.


go_id: GO:0035164
term: embryonic plasmatocyte differentiation
ontology: BP
definition:
The process in which an embryonic mesoderm-derived hemocyte precursor cell acquires the specialized features of the phagocytic blood-cell type, the plasmatocyte.


go_id: GO:0035165
term: embryonic crystal cell differentiation
ontology: BP
definition:
The process in which an embryonic mesoderm-derived hemocyte precursor cell acquires the specialized features of a crystal cell. Crystal cells are a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph.


go_id: GO:0035167
term: larval lymph gland hemopoiesis
ontology: BP
definition:
The production of blood cells from the larval lymph gland. The lymph gland consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages.


go_id: GO:0035168
term: larval lymph gland hemocyte differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell derived from the larval lymph gland acquires the specialized features of a mature hemocyte. The lymph gland consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this process is found in Drosophila melanogaster.


go_id: GO:0035169
term: lymph gland plasmatocyte differentiation
ontology: BP
definition:
The process in which a relatively unspecialized larval lymph gland-derived hemocyte precursor cell acquires the specialized features of the phagocytic blood-cell type, the plasmatocyte.


go_id: GO:0035170
term: lymph gland crystal cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized larval lymph gland-derived hemocyte precursor cell acquires the specialized features of a crystal cell. Crystal cells are a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph.


go_id: GO:0035171
term: lamellocyte differentiation
ontology: BP
definition:
The process in which a relatively unspecialized hemocyte precursor cell acquires the specialized features of a lamellocyte. Lamellocytes are a hemocyte lineage that exists only in larvae, but are seldom observed in healthy animals. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes.


go_id: GO:0035172
term: hemocyte proliferation
ontology: BP
definition:
The multiplication or reproduction of hemocytes, resulting in the expansion of the cell population. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen.


go_id: GO:0035175
term: histone kinase activity (H3-S10 specific)
ontology: MF
definition:
Catalysis of the transfer of a phosphate group to the serine-10 residue of the N-terminal tail of histone H3.


go_id: GO:0035176
term: social behavior
ontology: BP
definition:
Behavior directed towards society, or taking place between members of the same species. Occurs predominantly, or only, in individuals that are part of a group.


go_id: GO:0035178
term: turning behavior
ontology: BP
definition:
Fine-tuning the spatial position of an organism in response to variability in their environment. For example, reorientation of an organism in the direction of a food source.


go_id: GO:0035179
term: larval turning behavior
ontology: BP
definition:
Fine-tuning the spatial position of a larva in response to variability in their environment. For example, reorientation of a larva in the direction of a food source.


go_id: GO:0035180
term: larval wandering behavior
ontology: BP
definition:
The movement of a third instar larva through a substrate in search of a pupation site. This movement occurs without feeding and is characterized by short bursts of forward movement, separated by stops and repeated side-to-side head probes, followed normally by a change in direction.


go_id: GO:0035181
term: larval burrowing behavior
ontology: BP
definition:
Digging into the substrate by non-feeding larvae in search for food-free sites suitable for pupation.


go_id: GO:0035182
term: female germline ring canal outer rim
ontology: CC
definition:
An electron opaque backbone of the insect ovarian ring canal that is a part of or adjacent to the plasma membrane. The outer rim is established as the cleavage furrow is arrested, and contains F-actin, anillin, glycoproteins and at least one a protein with a high content of phosphorylated tyrosine residues.


go_id: GO:0035183
term: female germline ring canal inner rim
ontology: CC
definition:
A proteinaceous actin-rich layer of the insect ovarian ring canal that forms subcortically to the outer rim. The electron dense inner rim accumulates after the final mitotic division of each germline syncytia, and contains actin, a phosphotyrosine protein, and a number of cytoskeletal proteins.


go_id: GO:0035185
term: preblastoderm mitotic cell cycle
ontology: BP
definition:
The first nine mitotic division cycles of the insect embryo, during which the dividing nuclei lie deep in the interior of the egg and divide nearly synchronously. This is the first phase of the syncytial period where nuclei divide in a common cytoplasm without cytokinesis.


go_id: GO:0035186
term: syncytial blastoderm mitotic cell cycle
ontology: BP
definition:
Mitotic division cycles 10 to 13 of the insect embryo. This is the second phase of the syncytial period where nuclei divide in a common cytoplasm without cytokinesis. The majority of migrating nuclei reach the embryo surface during cycle 10, after which they divide less synchronously than before, and the syncytial blastoderm cycles lengthen progressively.


go_id: GO:0035187
term: hatching behavior
ontology: BP
definition:
The specific behavior of an organism during the emergence from an egg shell. In Drosophila for example, the larva swings its head reiteratively through a semicircular arc, using its mouth hooks to tear apart the chorion in front of it and thus free itself from within the egg shell.


go_id: GO:0035189
term: Rb-E2F complex
ontology: CC
definition:
A multiprotein complex containing a heterodimeric E2F transcription factor and a Retinoblastoma (Rb) family member. This complex is capable of repressing transcription of E2F-regulated genes in order to regulate cell cycle progression.


go_id: GO:0035190
term: syncytial nuclear migration
ontology: BP
definition:
The directed movement of nuclei within the syncytial embryo of insects. These precise temporal and spatial patterns of nuclear movement are coordinated with mitotic divisons and are required during blastoderm formation to reposition dividing nuclei from the interior of the syncytial embryo to the cortex.


go_id: GO:0035191
term: nuclear axial expansion
ontology: BP
definition:
The stepwise asymmetric spreading out of nuclei internally along the anterior-posterior axis of the developing insect embryo during mitotic cycles 4 to 6. This movement leads to the distribution of nuclei in a hollow ellipsoid underlying the cortex.


go_id: GO:0035192
term: nuclear cortical migration
ontology: BP
definition:
The symmetric outward movement of the syncytial nuclei from their positions in the ellipsoid toward the periphery of the embryo, during mitotic cycles 8 and 9. This movement results in the placement of nuclei in a uniform monolayer at the cortex of the developing embryo.


go_id: GO:0035193
term: larval central nervous system remodeling
ontology: BP
definition:
Reorganization of the pre-existing, functional larval central nervous system into one that can serve the novel behavioral needs of the adult. An example of this process is found in Drosophila melanogaster.


go_id: GO:0035194
term: post-transcriptional gene silencing by RNA
ontology: BP
definition:
A posttranscriptional gene silencing pathway in which regulatory RNAs elicit silencing of specific target genes, either by mRNA destabilization or inhibition of translation.


go_id: GO:0035195
term: miRNA-mediated gene silencing
ontology: BP
definition:
A post-transcriptional gene silencing pathway in which regulatory microRNAs (miRNAs) elicit silencing of specific target genes. miRNAs are endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: endonucleolytic cleavage of the RNA (often mRNA) or mRNA translational repression, usually accompanied by poly-A tail shortening and subsequent degradation of the mRNA. miRNAs are present in all the animals and in plants, whereas siRNAs are present in lower animals and in plants.


go_id: GO:0035196
term: miRNA processing
ontology: BP
definition:
A process leading to the generation of a functional miRNA. Includes the cleavage of stem-loop RNA precursors into microRNAs (miRNAs). miRNAs are a class of small RNAs that primarily silence genes by blocking the translation of mRNA transcripts into protein, or by increasing the degradation of non-protein-coding RNA transcripts.


go_id: GO:0035197
term: siRNA binding
ontology: MF
definition:
Binding to a small interfering RNA, a 21-23 nucleotide RNA that is processed from double stranded RNA (dsRNA) by an RNAse enzyme.


go_id: GO:0035198
term: miRNA binding
ontology: MF
definition:
Binding to a microRNA, a 21-23 nucleotide RNA that is processed from a stem-loop RNA precursor (pre-miRNA) that is encoded within plant and animal genomes.


go_id: GO:0035200
term: leg disc anterior/posterior pattern formation
ontology: BP
definition:
The establishment, maintenance and elaboration of the anterior/posterior axis of the leg imaginal disc.


go_id: GO:0035201
term: leg disc anterior/posterior lineage restriction
ontology: BP
definition:
Formation and/or maintenance of a lineage boundary between anterior and posterior compartments of the leg disc that cells cannot cross, thus separating the populations of cells in each compartment.


go_id: GO:0035202
term: tracheal pit formation in open tracheal system
ontology: BP
definition:
Formation of the tracheal pits, the first tube-like structures to form in the open tracheal system. Once cells are determined to their tracheal cell fate, the tracheal pits arise by invagination of each ectodermal cluster of tracheal placode cells, between 5 and 7 hours after egg laying. An example of this is found in Drosophila melanogaster.


go_id: GO:0035203
term: regulation of lamellocyte differentiation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes.


go_id: GO:0035204
term: negative regulation of lamellocyte differentiation
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes.


go_id: GO:0035205
term: positive regulation of lamellocyte differentiation
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes.


go_id: GO:0035206
term: regulation of hemocyte proliferation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster.


go_id: GO:0035207
term: negative regulation of hemocyte proliferation
ontology: BP
definition:
Any process that stops, prevents or reduces the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster.


go_id: GO:0035208
term: positive regulation of hemocyte proliferation
ontology: BP
definition:
Any process that activates or increases the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) that are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this process is found in Drosophila melanogaster.


go_id: GO:0035209
term: pupal development
ontology: BP
definition:
The process whose specific outcome is the progression of the pupa over time, from its formation to the mature structure. The pupa is a dormant life stage interposed between the larval and the adult stages in insects that undergo a complete metamorphosis.


go_id: GO:0035210
term: prepupal development
ontology: BP
definition:
The process whose specific outcome is the progression of the prepupa over time, from its formation to the mature structure. The prepupal stage is a life stage interposed between the larval and the pupal stages in insects that undergo a complete metamorphosis. The start of the pre-pupal stage is marked by pupariation, and the end is marked by pupation.


go_id: GO:0035211
term: spermathecum morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of a spermathecum, a sperm storage organ, are generated and organized. Paired spermathecae lie at the anterior end of the insect uterus on the dorsal side. Each spermatheca consists of an oval shaped capsule, connected to the uterus by a spermathecal stalk.


go_id: GO:0035212
term: cell competition in a multicellular organism
ontology: BP
definition:
Competitive interactions within multicellular organisms between cell populations that differ in growth rates, leading to the elimination of the slowest-growing cells.


go_id: GO:0035213
term: clypeo-labral disc development
ontology: BP
definition:
The process whose specific outcome is the progression of the clypeo-labral disc over time, from its formation to the metamorphosis to form adult structures. The clypeo-labral disc develops into the labrum, anterior cibarial plate, fish trap bristles, epistomal sclerite.


go_id: GO:0035214
term: eye-antennal disc development
ontology: BP
definition:
Progression of the eye-antennal imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including the eye, antenna, head capsule and maxillary palps.


go_id: GO:0035215
term: genital disc development
ontology: BP
definition:
Progression of the genital imaginal disc over time, from its initial formation through to its metamorphosis to form the adult terminalia, comprising the entire set of internal and external genitalia and analia. Both sexes of Drosophila have a single genital disc formed from the female and male genital primordia, and the anal primordium. The anal primordium develops in both sexes, forming either male or female analia. However, only one of the genital primordia develops in each sex, forming either the male or the female genitalia.


go_id: GO:0035216
term: haltere disc development
ontology: BP
definition:
Progression of the haltere imaginal disc over time, from its initial formation through to its metamorphosis to form the adult capitellum, pedicel, haltere sclerite, metathoracic spiracle and metanotum.


go_id: GO:0035217
term: labial disc development
ontology: BP
definition:
Progression of the labial imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including parts of the proboscis.


go_id: GO:0035218
term: leg disc development
ontology: BP
definition:
Progression of the leg imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including the leg, coxa and ventral thoracic pleura.


go_id: GO:0035219
term: prothoracic disc development
ontology: BP
definition:
Progression of the prothoracic disc over time, from its initial formation through to its metamorphosis to form the adult humerous and anterior spiracle.


go_id: GO:0035220
term: wing disc development
ontology: BP
definition:
Progression of the wing disc over time, from its initial formation through to its metamorphosis to form adult structures including the wing hinge, wing blade and pleura.


go_id: GO:0035221
term: genital disc pattern formation
ontology: BP
definition:
The process that gives rise to the patterns of cell differentiation that will arise in the genital imaginal disc.


go_id: GO:0035224
term: genital disc anterior/posterior pattern formation
ontology: BP
definition:
The establishment, maintenance and elaboration of the anterior/posterior axis of the genital disc. An anterior and posterior compartment form in each of the three genital disc primoridia (the female genital disc primordium, the male genital disc primordium and the anal primordium).


go_id: GO:0035225
term: determination of genital disc primordium
ontology: BP
definition:
Allocation of embryonic cells to the genital imaginal disc founder populations. Early in development at the blastoderm stage, the anlage of the genital disc of both sexes consists of three primordia: the female genital primoridum lcoated anteriorly, the anal primoridum located posteriorly, and the male gential primordium between the two.


go_id: GO:0035229
term: positive regulation of glutamate-cysteine ligase activity
ontology: BP
definition:
Any process that activates or increases the activity of glutamate-cysteine ligase, typically by lowering its sensitivity to inhibition by glutathione and by increasing its affinity for glutamate.


go_id: GO:0035230
term: cytoneme
ontology: CC
definition:
A long, thin, polarized cell projection that contains actin and can extend for distances many times the diameter of the cell. Cytonemes represent extensions of cell cytoplasm and typically have a diameter of approximately 0.2um.


go_id: GO:0035231
term: cytoneme assembly
ontology: BP
definition:
Formation of a cytoneme, a long, thin and polarized actin-based cytoplasmic extension that projects from a cell.


go_id: GO:0035232
term: germ cell attraction
ontology: BP
definition:
The directed movement of a germ cell from their site of production to the gonad, through the attraction of cells towards their target.


go_id: GO:0035233
term: germ cell repulsion
ontology: BP
definition:
The directed movement of a germ cell from their site of production to the gonad, through the repulsion of cells away from a tissue.


go_id: GO:0035234
term: ectopic germ cell programmed cell death
ontology: BP
definition:
Programmed cell death of an errant germ line cell that is outside the normal migratory path or ectopic to the gonad. This is an important mechanism of regulating germ cell survival within the embryo.


go_id: GO:0035235
term: ionotropic glutamate receptor signaling pathway
ontology: BP
definition:
The series of molecular signals initiated by glutamate binding to a glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex, and ending with the regulation of a downstream cellular process, e.g. transcription.


go_id: GO:0035238
term: vitamin A biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of any of the vitamin A compounds, retinol, retinal (retinaldehyde) and retinoic acid. Animals cannot synthesize vitamin A de novo, but form it through oxidative cleavage of carotenoids.


go_id: GO:0035239
term: tube morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of a tube are generated and organized. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system.


go_id: GO:0035240
term: dopamine binding
ontology: MF
definition:
Binding to dopamine, a catecholamine neurotransmitter formed by aromatic-L-amino-acid decarboxylase from 3,4-dihydroxy-L-phenylalanine.


go_id: GO:0035241
term: protein-arginine omega-N monomethyltransferase activity
ontology: MF
definition:
Catalysis of the addition of a methyl group to either of the unmethylated terminal nitrogen atoms (also called omega nitrogen) in peptidyl-arginine to form an omega-N-G-monomethylated arginine residue.  The reaction is S-adenosyl-L-methionine + [protein]-L-arginine = S-adenosyl-L-homocysteine + [protein]-Nomega-methyl-L-arginine.


go_id: GO:0035242
term: protein-arginine omega-N asymmetric methyltransferase activity
ontology: MF
definition:
Catalysis of the addition of a second methyl group to methylated peptidyl-arginine. Methylation is on the same terminal nitrogen (omega nitrogen) residue that was previously methylated, resulting in asymmetrical peptidyl-N(omega),N(omega)-dimethylated arginine residues.


go_id: GO:0035243
term: protein-arginine omega-N symmetric methyltransferase activity
ontology: MF
definition:
Catalysis of the addition of a second methyl group to methylated peptidyl-arginine. Methylation is on the terminal nitrogen (omega nitrogen) residue that is not already methylated, resulting in symmetrical peptidyl-N(omega),N'(omega)-dimethyled arginine residues.


go_id: GO:0035247
term: peptidyl-arginine omega-N-methylation
ontology: BP
definition:
The addition of a methyl group onto a terminal nitrogen (omega nitrogen) atom of an arginine residue in a protein.


go_id: GO:0035248
term: alpha-1,4-N-acetylgalactosaminyltransferase activity
ontology: MF
definition:
Catalysis of the transfer of an N-acetylgalactosaminyl residue from UDP-N-acetyl-galactosamine to an acceptor molecule, forming an alpha-1,4 linkage.


go_id: GO:0035249
term: synaptic transmission, glutamatergic
ontology: BP
definition:
The vesicular release of glutamate from a presynapse, across a chemical synapse, the subsequent activation of glutamate receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.


go_id: GO:0035253
term: ciliary rootlet
ontology: CC
definition:
A cytoskeleton-like structure, originating from the basal body at the proximal end of a cilium, and extending proximally toward the cell nucleus. Rootlets are typically 80-100 nm in diameter and contain cross striae distributed at regular intervals of approximately 55-70 nm.


go_id: GO:0035255
term: ionotropic glutamate receptor binding
ontology: MF
definition:
Binding to an ionotropic glutamate receptor. Ionotropic glutamate receptors bind glutamate and exert an effect through the regulation of ion channels.


go_id: GO:0035260
term: internal genitalia morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the internal genitalia are generated and organized. The internal genitalia are the internal sex organs such as the uterine tube, the uterus and the vagina in female mammals, and the testis, seminal vesicle, ejaculatory duct and prostate in male mammals.


go_id: GO:0035261
term: external genitalia morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the external genitalia are generated and organized. The external genitalia are the outer sex organs, such as the penis or vulva in mammals.


go_id: GO:0035262
term: gonad morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the gonads are generated and organized. A gonad is an animal organ producing gametes, e.g. the testes or the ovary in mammals.


go_id: GO:0035263
term: genital disc sexually dimorphic development
ontology: BP
definition:
The sex-specific patterns of primoridia growth and differentiation in the genital imaginal disc. The anal primordium of the genital disc develops in both sexes, but depending on the genetic sex gives rise to either male or female analia. Depending on the genetic sex, only one of the two genital primordia develop. In females the female genital primordium develops and gives rise to the female genitalia whereas the male primordium is repressed. Conversely, in males the male genital primordium develops and gives rise to the male genitalia whereas the female genital primordium is repressed.


go_id: GO:0035265
term: organ growth
ontology: BP
definition:
The increase in size or mass of an organ. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that function together as to perform a specific function.


go_id: GO:0035266
term: meristem growth
ontology: BP
definition:
The increase in size or mass of a meristem, a region of tissue in a plant that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation.


go_id: GO:0035267
term: NuA4 histone acetyltransferase complex
ontology: CC
definition:
A complex having histone acetylase activity on chromatin, as well as ATPase, DNA helicase and structural DNA binding activities. The complex is thought to be involved in double-strand DNA break repair. Subunits of the human complex include HTATIP/TIP60, TRRAP, RUVBL1, BUVBL2, beta-actin and BAF53/ACTL6A. In yeast, the complex has 13 subunits, including the catalytic subunit Esa1 (homologous to human Tip60).


go_id: GO:0035269
term: protein O-linked mannosylation
ontology: BP
definition:
The transfer of mannose from dolichyl activated mannose to the hydroxyl group of a seryl or threonyl residue of a protein acceptor molecule, to form an O-linked protein-sugar linkage.


go_id: GO:0035270
term: endocrine system development
ontology: BP
definition:
Progression of the endocrine system over time, from its formation to a mature structure. The endocrine system is a system of hormones and ductless glands, where the glands release hormones directly into the blood, lymph or other intercellular fluid, and the hormones circulate within the body to affect distant organs. The major glands that make up the human endocrine system are the hypothalamus, pituitary, thyroid, parathryoids, adrenals, pineal body, and the reproductive glands which include the ovaries and testes.


go_id: GO:0035271
term: ring gland development
ontology: BP
definition:
Progression of the ring gland over time, from its formation to a mature structure. The ring gland is a neuroendocrine organ found in higher Dipterans, which is composed of the prothoracic gland, the corpus allatum, and the corpora cardiacum. The ring gland is the site of production and release of ecdysteroids and juvenile hormones.


go_id: GO:0035272
term: exocrine system development
ontology: BP
definition:
Progression of the exocrine system over time, from its formation to a mature structure. The exocrine system is a system of hormones and glands, where the glands secrete straight to a target site via ducts or tubes. The human exocrine system includes the salivary glands, sweat glands and many glands of the digestive system.


go_id: GO:0035277
term: spiracle morphogenesis, open tracheal system
ontology: BP
definition:
The process in which the anatomical structures of a spiracle are generated and organized. Spiracles are the openings in the insect open tracheal system; externally they connect to the epidermis and internally they connect to the tracheal trunk.


go_id: GO:0035278
term: miRNA-mediated gene silencing by inhibition of translation
ontology: BP
definition:
An RNA interference pathway in which microRNAs (miRNAs) block the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA will typically mediate repression of translation if the miRNA imperfectly base-pairs with the 3' untranslated regions of target mRNAs.


go_id: GO:0035279
term: miRNA-mediated gene silencing by mRNA destabilization
ontology: BP
definition:
An RNA interference pathway in which microRNAs (miRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA base pairing with near-perfect complementarity to the target mRNA will typically direct targeted endonucleolytic cleavage of the mRNA. Many plant miRNAs downregulate gene expression through this mechanism.


go_id: GO:0035281
term: pre-miRNA export from nucleus
ontology: BP
definition:
Transport of pre-microRNAs (pre-miRNAs) from the nucleus to the cytoplasm. Pre-miRNAs are a ~60-70 nucleotide stem loop intermediate in miRNA production, produced by the nuclear cleavage of a primary miRNA (pri-mRNA) transcript. Pre-miRNAs are transported from the nucleus to the cytoplasm where further cleavage occurs to produce a mature miRNA product.


go_id: GO:0035282
term: segmentation
ontology: BP
definition:
The regionalization process that divides an organism or part of an organism into a series of semi-repetitive parts, or segments, often arranged along a longitudinal axis.


go_id: GO:0035285
term: appendage segmentation
ontology: BP
definition:
Division of an appendage, an organ or part that is attached to the main body of an organism, into a series of semi-repetitive parts or segments. Most arthropod appendages, such as the legs and antennae, are visibly segmented.


go_id: GO:0035287
term: head segmentation
ontology: BP
definition:
Partitioning the insect head anlage into a fixed number of segmental units. The number of segments composing the insect head has long been a subject of debate, but it is generally agreed that there are 6 or 7 segments. From anterior to posterior the head segments are the procephalic segments (labral, (ocular), antennal and intercalary) and the gnathal segments (mandibular, maxillary and labial).


go_id: GO:0035288
term: anterior head segmentation
ontology: BP
definition:
Partitioning the insect head anlage into procephalic (labral, (ocular), antennal and intercalary) segments. The procephalic segments lie anterior to the gnathal (posterior head) segments, and are pattered by different segmentation gene cascades to the abdominal, thoracic and posterior head (gnathal) segments.


go_id: GO:0035289
term: posterior head segmentation
ontology: BP
definition:
Partitioning the posterior region of the insect head anlage into gnathal (mandibular, maxillary and labial) segments. Unlike the anterior head (procephalic) segments, formation of the posterior head (gnathal) segments occurs by a similar mechanism to trunk segmentation, where a cascade of gap genes, pair-rule genes and segment-polarity genes subdivide the embryo into progressively smaller domains.


go_id: GO:0035290
term: trunk segmentation
ontology: BP
definition:
Partitioning of the blastoderm embryo into trunk segmental units. In Drosophila, the trunk segments include thoracic segments and abdominal segments A1 to A8.


go_id: GO:0035291
term: specification of segmental identity, intercalary segment
ontology: BP
definition:
The specification of the characteristic structures of the intercalary segment of the anterior head, following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.


go_id: GO:0035292
term: specification of segmental identity, trunk
ontology: BP
definition:
The specification of the characteristic structures of trunk segments, following establishment of segment boundaries. In Drosophila, the trunk segments include thoracic segments and abdominal segments A1 to A8. Identity is considered to be the aggregate of characteristics by which a structure is recognized.


go_id: GO:0035293
term: chitin-based larval cuticle pattern formation
ontology: BP
definition:
The process that gives rise to the patterns of cell differentiation in the chitin-based larval cuticle. An example of this is found in Drosophila melanogaster.


go_id: GO:0035294
term: determination of wing disc primordium
ontology: BP
definition:
Allocation of embryonic cells to the wing disc founder populations, groups of cells that are committed to contribute to the formation of a wing imaginal disc.


go_id: GO:0035295
term: tube development
ontology: BP
definition:
The process whose specific outcome is the progression of a tube over time, from its initial formation to a mature structure. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues including lung and trachea, kidney, the mammary gland, the vascular system and the gastrointestinal and urinary-genital tracts.


go_id: GO:0035297
term: regulation of Malpighian tubule diameter
ontology: BP
definition:
Ensuring that the Malpighian tubule is the correct width. Malpighian tubules have a uniform circumference along their length; the circumference of the tubes is eight cells during the time the cells are dividing, after which the cells rearrange producting tubes with a cirumference of two cells.


go_id: GO:0035299
term: inositol pentakisphosphate 2-kinase activity
ontology: MF
definition:
Catalysis of the reaction: 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ATP = 1D-myo-inositol hexakisphosphate + ADP + 2 H(+).


go_id: GO:0035301
term: Hedgehog signaling complex
ontology: CC
definition:
A multiprotein complex that binds microtubules in a Hedgehog-dependent manner, and is required for signal transduction by members of the Hedgehog family of proteins. The core components of the complex are the serine/threonine protein kinase Fused, the kinesin motor protein Costal2 (Cos2), and a zinc finger transcription factor (Gli family members in humans, and Cubitus interruptus (Ci) in Drosophila).


go_id: GO:0035302
term: ecdysteroid 25-hydroxylase activity
ontology: MF
definition:
Catalysis of the hydroxylation of an ecdysteroid at carbon position 25. Ecdysteroids are a group of polyhydroxylated ketosteroids which initiate post-embryonic development, particularly metamorphosis, in insects and other arthropods.


go_id: GO:0035303
term: regulation of dephosphorylation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of removal of phosphate groups from a molecule.


go_id: GO:0035304
term: regulation of protein dephosphorylation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of removal of phosphate groups from a protein.


go_id: GO:0035305
term: negative regulation of dephosphorylation
ontology: BP
definition:
Any process the stops, prevents, or reduces the frequency, rate or extent of removal of phosphate groups from a molecule.


go_id: GO:0035306
term: positive regulation of dephosphorylation
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of removal of phosphate groups from a molecule.


go_id: GO:0035307
term: positive regulation of protein dephosphorylation
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of removal of phosphate groups from a protein.


go_id: GO:0035308
term: negative regulation of protein dephosphorylation
ontology: BP
definition:
Any process the stops, prevents, or reduces the frequency, rate or extent of removal of phosphate groups from a protein.


go_id: GO:0035309
term: wing and notum subfield formation
ontology: BP
definition:
The regionalization process that subdivides the wing imaginal disc into the wing and notum (body wall) subfields, thus determining whether cells ultimately differentiate wing or notum-specific structures.


go_id: GO:0035310
term: notum cell fate specification
ontology: BP
definition:
The process in which a cell in the larval wing imaginal disc becomes capable of differentiating autonomously into a notum cell, if left in its normal environment.


go_id: GO:0035311
term: wing cell fate specification
ontology: BP
definition:
The process in which a cell in the larval wing imaginal disc becomes capable of differentiating autonomously into a wing cell, if left in its normal environment.


go_id: GO:0035313
term: wound healing, spreading of epidermal cells
ontology: BP
definition:
The migration of an epidermal cell along or through a wound gap that contributes to the reestablishment of a continuous epidermis.


go_id: GO:0035314
term: scab formation
ontology: BP
definition:
Formation of hardened covering (a scab) at a wound site. The scab has multiple functions including limiting blood loss, providing structural stability to the wound and guarding against infection.


go_id: GO:0035316
term: non-sensory hair organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of non-sensory hairs. These hairs are polarized cellular extensions that cover much of the insect epidermis.


go_id: GO:0035317
term: imaginal disc-derived wing hair organization
ontology: BP
definition:
A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of an imaginal disc-derived wing hair. A wing hair is an actin-rich, polarized, non-sensory apical projection that protrudes from each of the approximately 30,000 wing epithelial cells. An example of this is found in Drosophila melanogaster.


go_id: GO:0035318
term: imaginal disc-derived wing hair outgrowth
ontology: BP
definition:
Extrusion of a cellular projection from the apical membrane of an epithelial cell in an imaginal disc-derived wing. Outgrowth initiates approximately 35 hours after puparium formation from the distal side of the cell, and at this stage the cellular extension is termed a prehair.


go_id: GO:0035319
term: imaginal disc-derived wing hair elongation
ontology: BP
definition:
Growth of a prehair in the approximately 10 hour period following its emergence from an epidermal cell in an imaginal disc-derived wing. Prehair elongation is guided and/or driven by the polymerization of actin filaments and the orderly crosslinking of filaments into bundles.


go_id: GO:0035320
term: imaginal disc-derived wing hair site selection
ontology: BP
definition:
Determination of the site in the cell of an imaginal disc-derived wing at which a prehair initiates outgrowth. Restriction of prehair initiation to the distalmost part of a cell is essential to ensure that each wing epithelial cell produces one adult hair that points distally.


go_id: GO:0035321
term: maintenance of imaginal disc-derived wing hair orientation
ontology: BP
definition:
Ensuring that hairs in the imaginal disc-derived wing continue to point distally during development, following the initial establishment of wing hair polarity.


go_id: GO:0035322
term: mesenchymal cell migration involved in limb bud formation
ontology: BP
definition:
The orderly movement of a mesenchymal cell from one site to another that will contribute to the formation of a limb bud.


go_id: GO:0035325
term: Toll-like receptor binding
ontology: MF
definition:
Binding to a Toll-like protein, a pattern recognition receptor that binds pattern motifs from a variety of microbial sources to initiate an innate immune response.


go_id: GO:0035329
term: hippo signaling
ontology: BP
definition:
The series of molecular signals mediated by the serine/threonine kinase Hippo or one of its orthologs. In Drosophila, Hippo in complex with the scaffold protein Salvador (Sav), phosphorylates and activates Warts (Wts), which in turn phosphorylates and inactivates the Yorkie (Yki) transcriptional activator. The core fly components hippo, sav, wts and mats are conserved in mammals as STK4/3 (MST1/2), SAV1/WW45, LATS1/2 and MOB1.


go_id: GO:0035333
term: Notch receptor processing, ligand-dependent
ontology: BP
definition:
The proteolytic cleavages to the Notch protein that occur as a result of ligand binding. Ligand binding at the cell surface exposes an otherwise inaccessible cleavage site in the extracellular portion of Notch, which when cleaved releases a membrane-tethered form of the Notch intracellular domain. Subsequent cleavage within the transmembrane domain then leads to the release of the soluble Notch intracellular domain (NICD).


go_id: GO:0035334
term: Notch receptor processing, ligand-independent
ontology: BP
definition:
The proteolytic cleavages to the Notch protein that occur prior to ligand binding. A primary cleavage event within the extracellular domain whilst the Notch protein in still in the secretory pathway, leads to the transportation of a processed heterodimer to the cell surface.


go_id: GO:0035336
term: long-chain fatty-acyl-CoA metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. Long-chain fatty-acyl-CoAs have chain lengths of C13 or more.


go_id: GO:0035337
term: fatty-acyl-CoA metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group.


go_id: GO:0035338
term: long-chain fatty-acyl-CoA biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a long-chain fatty-acyl-CoA any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. Long-chain fatty-acyl-CoAs have chain lengths of C13 or more.


go_id: GO:0035339
term: SPOTS complex
ontology: CC
definition:
A multiprotein complex at least composed of serine palmitoyltransferases and ORM proteins (known as ORMDL proteins in mammals and other higher vertebrates) that plays a key role in sphingolipid homeostasis.


go_id: GO:0035340
term: inosine transport
ontology: BP
definition:
The directed movement of the purine ribonucleoside inosine, also known as hypoxanthine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0035341
term: regulation of inosine transport
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0035342
term: positive regulation of inosine transport
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0035343
term: negative regulation of inosine transport
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0035344
term: hypoxanthine transport
ontology: BP
definition:
The directed movement of hypoxanthine, 6-hydroxypurine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0035345
term: regulation of hypoxanthine transport
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0035346
term: positive regulation of hypoxanthine transport
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0035347
term: negative regulation of hypoxanthine transport
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0035348
term: acetyl-CoA transmembrane transport
ontology: BP
definition:
The process in which acetyl-CoA is transported across a membrane. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.


go_id: GO:0035349
term: coenzyme A transmembrane transport
ontology: BP
definition:
The process in which coenzyme A is transported across a membrane. Coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, is an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.


go_id: GO:0035350
term: FAD transmembrane transport
ontology: BP
definition:
The process in which flavin-adenine dinucleotide (FAD) is transported across a membrane. FAD forms the coenzyme of the prosthetic group of various flavoprotein oxidoreductase enzymes, in which it functions as an electron acceptor by being reversibly converted to its reduced form.


go_id: GO:0035351
term: heme transmembrane transport
ontology: BP
definition:
The process in which heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.


go_id: GO:0035352
term: NAD transmembrane transport
ontology: BP
definition:
The process in which a nicotinamide adenine dinucleotide is transported across a membrane; transport may be of either the oxidized form, NAD, or the reduced form, NADH.


go_id: GO:0035353
term: nicotinamide mononucleotide transmembrane transport
ontology: BP
definition:
The process in which nicotinamide mononucleotide is transported across a membrane. Nicotinamide mononucleotide is a ribonucleotide in which the nitrogenous base, nicotinamide, is in beta-n-glycosidic linkage with the c-1 position of d-ribose. It is a constituent of NAD and NADP.


go_id: GO:0035354
term: Toll-like receptor 1-Toll-like receptor 2 protein complex
ontology: CC
definition:
A heterodimeric protein complex containing Toll-like receptor 1 (TLR1) and Toll-like receptor 2 (TLR2).


go_id: GO:0035355
term: Toll-like receptor 2-Toll-like receptor 6 protein complex
ontology: CC
definition:
A heterodimeric protein complex containing Toll-like receptor 2 (TLR2) and Toll-like receptor 6 (TLR6).


go_id: GO:0035356
term: cellular triglyceride homeostasis
ontology: BP
definition:
Any process involved in the maintenance of an internal steady state of triglyceride within a cell or between a cell and its external environment.


go_id: GO:0035357
term: peroxisome proliferator activated receptor signaling pathway
ontology: BP
definition:
The series of molecular signals initiated by binding of a ligand to any of the peroxisome proliferator activated receptors (alpha, beta or gamma) in the nuclear membrane, and ending with the initiation or termination of the transcription of target genes.


go_id: GO:0035358
term: regulation of peroxisome proliferator activated receptor signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway.


go_id: GO:0035359
term: negative regulation of peroxisome proliferator activated receptor signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway.


go_id: GO:0035360
term: positive regulation of peroxisome proliferator activated receptor signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway.


go_id: GO:0035361
term: Cul8-RING ubiquitin ligase complex
ontology: CC
definition:
A ubiquitin ligase complex in which a cullin from the Cul8 subfamily and a RING domain protein form the catalytic core. In S. cerevisiae, Mms1p acts as the adaptor protein and substrate specificity is conferred by any of a number of different proteins.


go_id: GO:0035362
term: protein-DNA ISRE complex assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex, in which the complex is formed through interaction of the protein(s) with a interferon-stimulated response element (ISRE) in the DNA.


go_id: GO:0035363
term: histone locus body
ontology: CC
definition:
A nuclear body associated with the histone gene locus that is thought to contain all of the factors necessary for histone mRNA transcription and pre-mRNA processing. In Drosophila, U7 snRNP is located in the histone locus body rather than the distinct Cajal body.


go_id: GO:0035364
term: thymine transport
ontology: BP
definition:
The directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0035365
term: regulation of thymine transport
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0035366
term: negative regulation of thymine transport
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0035367
term: positive regulation of thymine transport
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0035368
term: selenocysteine insertion sequence binding
ontology: MF
definition:
Binding to a selenocysteine insertion sequence (SECIS), a regulatory sequence within mRNA which directs incorporation of a selenocysteine at a stop codon (UGA) during translation.


go_id: GO:0035369
term: pre-B cell receptor complex
ontology: CC
definition:
An immunoglobulin-like complex that is present in at least the plasma membrane of pre-B cells, and that is composed of two identical immunoglobulin heavy chains and two surrogate light chains, each composed of the lambda-5 and VpreB proteins, and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.


go_id: GO:0035370
term: UBC13-UEV1A complex
ontology: CC
definition:
A heterodimeric ubiquitin conjugating enzyme complex that catalyzes assembly of K63-linked polyubiquitin chains and is involved in NF-kappaB activation. In humans at least, the complex comprises the ubiquitin-conjugating enzyme UBC13 and ubiquitin-conjugating enzyme variant 1A (UEV1A).


go_id: GO:0035371
term: microtubule plus-end
ontology: CC
definition:
The growing (plus) end of a microtubule. In vitro, microtubules polymerize more quickly at the plus end than at the minus end. In vivo, microtubule growth occurs only at the plus end, and the plus end switches between periods of growth and shortening, a behavior known as dynamic instability.


go_id: GO:0035373
term: chondroitin sulfate proteoglycan binding
ontology: MF
definition:
Binding to a chondroitin sulfate proteoglycan, any proteoglycan containing chondroitin sulfate as the glycosaminoglycan carbohydrate unit.


go_id: GO:0035374
term: chondroitin sulfate binding
ontology: MF
definition:
Binding to chondroitin sulfate, a glycosaminoglycan made up of two alternating monosaccharides: D-glucuronic acid (GlcA) and N-acetyl-D-galactosamine (GalNAc).


go_id: GO:0035375
term: zymogen binding
ontology: MF
definition:
Binding to a zymogen, an enzymatically inactive precursor of an enzyme that is often convertible to an active enzyme by proteolysis.


go_id: GO:0035376
term: sterol import
ontology: BP
definition:
The directed movement of a sterol into a cell or organelle. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.


go_id: GO:0035380
term: very long-chain-3-hydroxyacyl-CoA dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD(P)+ = 3-oxoacyl-CoA + NAD(P)H + H+, where the acyl group is a very long-chain fatty acid residue. A very long-chain fatty acid is a fatty acid which has a chain length greater than C22.


go_id: GO:0035381
term: ATP-gated ion channel activity
ontology: MF
definition:
Enables the transmembrane transfer of an ion by a channel that opens when ATP has been bound by the channel complex or one of its constituent parts.


go_id: GO:0035382
term: sterol transmembrane transport
ontology: BP
definition:
The process in which a sterol is transported across a membrane. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.


go_id: GO:0035383
term: thioester metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving a thioester, a compound of general formula RC(=O)SR' in which the linking oxygen in an ester is replaced by a sulfur atom. They are the product of esterification between a carboxylic acid and a thiol.


go_id: GO:0035384
term: thioester biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a thioester, a compound of general formula RC(=O)SR' in which the linking oxygen in an ester is replaced by a sulfur atom. They are the product of esterification between a carboxylic acid and a thiol.


go_id: GO:0035385
term: Roundabout signaling pathway
ontology: BP
definition:
The series of molecular signals initiated by a SLIT protein binding to a Roundabout (ROBO) family receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


go_id: GO:0035387
term: negative regulation of Roundabout signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the Roundabout signaling pathway.


go_id: GO:0035388
term: positive regulation of Roundabout signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the Roundabout signaling pathway.


go_id: GO:0035393
term: chemokine (C-X-C motif) ligand 9 production
ontology: BP
definition:
The appearance of chemokine (C-X-C motif) ligand 9 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0035394
term: regulation of chemokine (C-X-C motif) ligand 9 production
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9.


go_id: GO:0035395
term: negative regulation of chemokine (C-X-C motif) ligand 9 production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9.


go_id: GO:0035396
term: positive regulation of chemokine (C-X-C motif) ligand 9 production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9.


go_id: GO:0035397
term: helper T cell enhancement of adaptive immune response
ontology: BP
definition:
Positive regulation of an adaptive immune response mediated via cytokine production by helper T cell.


go_id: GO:0035398
term: helper T cell enhancement of T cell mediated immune response
ontology: BP
definition:
Positive regulation of a T cell mediated immune response mediated via cytokine production by a helper T cell.


go_id: GO:0035399
term: helper T cell enhancement of B cell mediated immune response
ontology: BP
definition:
Positive regulation of a B cell mediated immune response mediated via cytokine production by a helper T cell.


go_id: GO:0035402
term: histone kinase activity (H3-T11 specific)
ontology: MF
definition:
Catalysis of the transfer of a phosphate group to the threonine-11 residue of the N-terminal tail of histone H3.


go_id: GO:0035403
term: histone kinase activity (H3-T6 specific)
ontology: MF
definition:
Catalysis of the transfer of a phosphate group to the threonine-6 residue of the N-terminal tail of histone H3.


go_id: GO:0035418
term: protein localization to synapse
ontology: BP
definition:
Any process in which a protein is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.


go_id: GO:0035425
term: autocrine signaling
ontology: BP
definition:
Signaling between cells of the same type. The signal produced by the signaling cell binds to a receptor on, and affects a cell of the same type.


go_id: GO:0035429
term: gluconate transmembrane transport
ontology: BP
definition:
The process in which gluconate is transported across a membrane. Gluconate is the aldonic acid derived from glucose.


go_id: GO:0035430
term: regulation of gluconate transmembrane transport
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the directed movement of a gluconate across a membrane by means of some agent such as a transporter or pore.


go_id: GO:0035431
term: negative regulation of gluconate transmembrane transport
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of gluconate across a membrane by means of some agent such as a transporter or pore.


go_id: GO:0035432
term: positive regulation of gluconate transmembrane transport
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the directed movement of gluconate across a membrane by means of some agent such as a transporter or pore.


go_id: GO:0035433
term: acetate transmembrane transport
ontology: BP
definition:
The process in which acetate is transported across a membrane. Acetate is the 2-carbon carboxylic acid ethanoic acid.


go_id: GO:0035436
term: triose phosphate transmembrane transport
ontology: BP
definition:
The process in which triose phosphate (glyceraldehyde 3-phosphate) is transported across a membrane. Glyceraldehyde 3-phosphate is any organic three carbon compound phosphate ester.


go_id: GO:0035437
term: maintenance of protein localization in endoplasmic reticulum
ontology: BP
definition:
Any process in which a protein is maintained in the endoplasmic reticulum and prevented from moving elsewhere. These include sequestration within the endoplasmic reticulum, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the endoplasmic reticulum.


go_id: GO:0035440
term: tuberculosinol biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of tuberculosinol (halima-5,6,dien-15-ol), a secondary metabolite in Mycobacteria.


