Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C17_R1.fastp-trim.20230215.fq.gz...
72a586656d07e43cd07dcc2f95174265  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C17_R1.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C17_R1.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.301s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.698s]
Opening the output file...  [0s]
Loading query sequences...  [76.157s]
Masking queries...  [19.664s]
Algorithm: Double-indexed
Building query histograms...  [17.791s]
Loading reference sequences...  [29.354s]
Masking reference...  [32.091s]
Initializing dictionary...  [0.081s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.546s]
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Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.506s]
Building query seed array...  [2.121s]
Computing hash join...  [5.255s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [80.595s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.117s]
Building query seed array...  [2.472s]
Computing hash join...  [5.089s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [52.134s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.241s]
Building query seed array...  [2.715s]
Computing hash join...  [5.058s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [45.9s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.286s]
Building query seed array...  [2.131s]
Computing hash join...  [5.12s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [41.457s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.049s]
Building query seed array...  [1.953s]
Computing hash join...  [4.936s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [41.419s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.675s]
Building query seed array...  [2.191s]
Computing hash join...  [4.914s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [33.191s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.75s]
Building query seed array...  [2.349s]
Computing hash join...  [4.988s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [35.87s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.087s]
Building query seed array...  [1.887s]
Computing hash join...  [4.85s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [30.883s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.618s]
Opening temporary output file...  [0.002s]
Computing alignments... Loading trace points...  [6.462s]
Sorting trace points...  [1.276s]
Computing alignments...  [32.716s]
Deallocating buffers...  [0.022s]
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Sorting trace points...  [1.227s]
Computing alignments...  [32.661s]
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Computing alignments...  [32.081s]
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Sorting trace points...  [1.264s]
Computing alignments...  [33.642s]
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Sorting trace points...  [1.292s]
Computing alignments...  [33.73s]
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Computing alignments...  [33.963s]
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Sorting trace points...  [1.295s]
Computing alignments...  [33.348s]
Deallocating buffers...  [0.024s]
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Sorting trace points...  [1.245s]
Computing alignments...  [33.33s]
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Sorting trace points...  [0.946s]
Computing alignments...  [33.129s]
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Sorting trace points...  [1.137s]
Computing alignments...  [32.909s]
Deallocating buffers...  [0.017s]
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Sorting trace points...  [1.235s]
Computing alignments...  [33.062s]
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Computing alignments...  [32.975s]
Deallocating buffers...  [0.018s]
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Sorting trace points...  [1.261s]
Computing alignments...  [33.212s]
Deallocating buffers...  [0.018s]
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Sorting trace points...  [1.285s]
Computing alignments...  [33.425s]
Deallocating buffers...  [0.022s]
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Sorting trace points...  [1.094s]
Computing alignments...  [33.378s]
Deallocating buffers...  [0.023s]
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Sorting trace points...  [1.222s]
Computing alignments...  [33.197s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
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Deallocating reference...  [0.079s]
Loading reference sequences...  [30.088s]
Masking reference...  [32.169s]
Initializing dictionary...  [0.08s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [31.942s]
Allocating buffers...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.393s]
Building query seed array...  [2.184s]
Computing hash join...  [5.124s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [78.024s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.55s]
Building query seed array...  [2.514s]
Computing hash join...  [5.201s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [53.348s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.921s]
Building query seed array...  [2.603s]
Computing hash join...  [5.042s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [45.404s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.259s]
Building query seed array...  [2.065s]
Computing hash join...  [5.126s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [39.833s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.635s]
Building query seed array...  [1.893s]
Computing hash join...  [4.883s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [41.062s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.455s]
Building query seed array...  [2.187s]
Computing hash join...  [4.906s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [32.726s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.499s]
Building query seed array...  [2.45s]
Computing hash join...  [4.894s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [36.048s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.23s]
Building query seed array...  [1.934s]
Computing hash join...  [4.917s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [30.091s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.659s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.63s]
Sorting trace points...  [1.274s]
Computing alignments...  [32.076s]
Deallocating buffers...  [0.015s]
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Sorting trace points...  [0.989s]
Computing alignments...  [32.362s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.188s]
Computing alignments...  [31.728s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.119s]
Computing alignments...  [33.694s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.235s]
Computing alignments...  [33.341s]
Deallocating buffers...  [0.024s]
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Sorting trace points...  [1.288s]
Computing alignments...  [33.529s]
Deallocating buffers...  [0.02s]
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Sorting trace points...  [1.28s]
Computing alignments...  [32.88s]
Deallocating buffers...  [0.021s]
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Sorting trace points...  [1.241s]
Computing alignments...  [33.413s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.016s]
Computing alignments...  [33.01s]
Deallocating buffers...  [0.022s]
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Sorting trace points...  [1.251s]
Computing alignments...  [32.767s]
Deallocating buffers...  [0.015s]
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Sorting trace points...  [1.181s]
Computing alignments...  [32.826s]
Deallocating buffers...  [0.017s]
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Sorting trace points...  [1.252s]
Computing alignments...  [32.846s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.206s]
Computing alignments...  [32.974s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.186s]
Computing alignments...  [33.136s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.246s]
Computing alignments...  [33.139s]
Deallocating buffers...  [0.021s]
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Sorting trace points...  [1.209s]
Computing alignments...  [33.091s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [554.201s]
Deallocating reference...  [0.078s]
Loading reference sequences...  [30.802s]
Masking reference...  [32.044s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.011s]
Building reference histograms...  [32.239s]
Allocating buffers...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.187s]
Building query seed array...  [2.129s]
Computing hash join...  [5.1s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [82.426s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.543s]
Building query seed array...  [2.495s]
Computing hash join...  [5.166s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [51.828s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.677s]
Building query seed array...  [2.57s]
Computing hash join...  [5.117s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [44.264s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.055s]
Building query seed array...  [2.103s]
Computing hash join...  [5.182s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [40.116s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.165s]
Building query seed array...  [1.945s]
Computing hash join...  [4.965s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [41.36s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.365s]
Building query seed array...  [2.174s]
Computing hash join...  [4.935s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [33.228s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.317s]
Building query seed array...  [2.341s]
Computing hash join...  [4.99s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [35.475s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.161s]
Building query seed array...  [1.955s]
Computing hash join...  [4.93s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [30.849s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.133s]
Clearing query masking...  [1.651s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.601s]
Sorting trace points...  [1.272s]
Computing alignments...  [32.117s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.192s]
Computing alignments...  [32.514s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.2s]
Computing alignments...  [32.019s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.318s]
Computing alignments...  [33.415s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.275s]
Computing alignments...  [33.703s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.271s]
Computing alignments...  [33.634s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.06s]
Sorting trace points...  [0.951s]
Computing alignments...  [32.895s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.257s]
Computing alignments...  [33.042s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.082s]
Sorting trace points...  [0.934s]
Computing alignments...  [32.921s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.028s]
Computing alignments...  [32.659s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.109s]
Sorting trace points...  [1.198s]
Computing alignments...  [32.744s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.07s]
Sorting trace points...  [0.976s]
Computing alignments...  [32.648s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.126s]
Computing alignments...  [33.033s]
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Loading trace points...  [0.063s]
Sorting trace points...  [1.307s]
Computing alignments...  [32.996s]
Deallocating buffers...  [0.024s]
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Sorting trace points...  [1.048s]
Computing alignments...  [33.07s]
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Computing alignments...  [33.013s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [552.847s]
Deallocating reference...  [0.075s]
Loading reference sequences...  [29.631s]
Masking reference...  [30.873s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.063s]
Allocating buffers...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.508s]
Building query seed array...  [2.084s]
Computing hash join...  [5.169s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [81.175s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.437s]
Building query seed array...  [2.514s]
Computing hash join...  [5.024s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [53.224s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.783s]
Building query seed array...  [2.681s]
Computing hash join...  [5.142s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [45.249s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.784s]
Building query seed array...  [2.048s]
Computing hash join...  [5.066s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [41.689s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.981s]
Building query seed array...  [1.929s]
Computing hash join...  [4.968s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [40.615s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.319s]
Building query seed array...  [2.203s]
Computing hash join...  [4.948s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [32.639s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.753s]
Building query seed array...  [2.403s]
Computing hash join...  [4.879s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [35.278s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.108s]
Building query seed array...  [1.916s]
Computing hash join...  [4.817s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [30.012s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.609s]
Opening temporary output file...  [0.002s]
Computing alignments... Loading trace points...  [7.131s]
Sorting trace points...  [1.262s]
Computing alignments...  [32.318s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.054s]
Computing alignments...  [32.473s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.04s]
Sorting trace points...  [1.2s]
Computing alignments...  [31.852s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.298s]
Computing alignments...  [33.409s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.077s]
Sorting trace points...  [0.998s]
Computing alignments...  [33.442s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.275s]
Computing alignments...  [33.72s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.269s]
Computing alignments...  [33s]
Deallocating buffers...  [0.021s]
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Sorting trace points...  [1.343s]
Computing alignments...  [32.854s]
Deallocating buffers...  [0.023s]
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Sorting trace points...  [0.974s]
Computing alignments...  [32.824s]
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Loading trace points...  [0.082s]
Sorting trace points...  [1.098s]
Computing alignments...  [32.722s]
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Sorting trace points...  [1.252s]
Computing alignments...  [32.844s]
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Loading trace points...  [0.101s]
Sorting trace points...  [1.017s]
Computing alignments...  [32.867s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.27s]
Computing alignments...  [32.97s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.087s]
Sorting trace points...  [1.262s]
Computing alignments...  [33.096s]
Deallocating buffers...  [0.024s]
Loading trace points...  [1.009s]
Sorting trace points...  [1.329s]
Computing alignments...  [33.117s]
Deallocating buffers...  [0.02s]
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Sorting trace points...  [1.045s]
Computing alignments...  [32.96s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
 [555.902s]
Deallocating reference...  [0.074s]
Loading reference sequences...  [29.586s]
Masking reference...  [30.851s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.586s]
Allocating buffers...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.297s]
Building query seed array...  [2.15s]
Computing hash join...  [5.11s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [78.721s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.024s]
Building query seed array...  [2.559s]
Computing hash join...  [5.133s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [52.801s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.268s]
Building query seed array...  [2.537s]
Computing hash join...  [5.021s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [44.696s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.896s]
Building query seed array...  [2.15s]
Computing hash join...  [5.139s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [40.173s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.023s]
Building query seed array...  [1.906s]
Computing hash join...  [4.912s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [39.921s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.296s]
Building query seed array...  [2.253s]
Computing hash join...  [5.026s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [33.6s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.143s]
Building query seed array...  [2.341s]
Computing hash join...  [4.855s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [35.469s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.765s]
Building query seed array...  [1.878s]
Computing hash join...  [4.915s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [30.469s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.631s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.615s]
Sorting trace points...  [1.264s]
Computing alignments...  [32.112s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.04s]
Sorting trace points...  [1.273s]
Computing alignments...  [32.254s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.193s]
Computing alignments...  [31.65s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.287s]
Computing alignments...  [33.213s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.073s]
Sorting trace points...  [0.973s]
Computing alignments...  [33.404s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.273s]
Computing alignments...  [33.549s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.138s]
Computing alignments...  [32.95s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.293s]
Computing alignments...  [32.9s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.27s]
Computing alignments...  [32.668s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.005s]
Computing alignments...  [32.593s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.12s]
Sorting trace points...  [1.233s]
Computing alignments...  [32.64s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.151s]
Computing alignments...  [32.724s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.04s]
Sorting trace points...  [1.007s]
Computing alignments...  [32.907s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.07s]
Sorting trace points...  [0.988s]
Computing alignments...  [32.982s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.095s]
Sorting trace points...  [1.277s]
Computing alignments...  [33.056s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
Sorting trace points...  [1.22s]
Computing alignments...  [33.059s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [551.404s]
Deallocating reference...  [0.082s]
Loading reference sequences...  [30.758s]
Masking reference...  [30.848s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.553s]
Allocating buffers...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.084s]
Building query seed array...  [2.178s]
Computing hash join...  [5.085s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [80.239s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.245s]
Building query seed array...  [2.495s]
Computing hash join...  [5.121s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [51.672s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.746s]
Building query seed array...  [2.682s]
Computing hash join...  [5.097s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [43.032s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.133s]
Building query seed array...  [2.116s]
Computing hash join...  [5.132s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [38.705s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.898s]
Building query seed array...  [1.936s]
Computing hash join...  [4.928s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [39.836s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.585s]
Building query seed array...  [2.224s]
Computing hash join...  [4.827s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [32.771s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.293s]
Building query seed array...  [2.321s]
Computing hash join...  [4.783s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [34.813s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.898s]
Building query seed array...  [1.894s]
Computing hash join...  [4.878s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [29.559s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.143s]
Clearing query masking...  [1.671s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.694s]
Sorting trace points...  [1.15s]
Computing alignments...  [31.897s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.869s]
Sorting trace points...  [1.278s]
Computing alignments...  [32.049s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.198s]
Computing alignments...  [31.47s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.175s]
Computing alignments...  [32.973s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.245s]
Computing alignments...  [32.994s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.174s]
Computing alignments...  [33.311s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.263s]
Computing alignments...  [32.541s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.294s]
Computing alignments...  [32.473s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.426s]
Computing alignments...  [32.431s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.212s]
Computing alignments...  [32.381s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.248s]
Computing alignments...  [32.542s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.238s]
Computing alignments...  [32.524s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.068s]
Sorting trace points...  [0.961s]
Computing alignments...  [32.751s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.059s]
Sorting trace points...  [0.949s]
Computing alignments...  [32.741s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.23s]
Computing alignments...  [32.853s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [0.992s]
Computing alignments...  [32.568s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [548.284s]
Deallocating reference...  [0.073s]
Loading reference sequences...  [29.607s]
Masking reference...  [32.198s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.074s]
Allocating buffers...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.545s]
Building query seed array...  [2.212s]
Computing hash join...  [5.167s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [81.828s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.646s]
Building query seed array...  [2.479s]
Computing hash join...  [5.082s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [52.325s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.899s]
Building query seed array...  [2.663s]
Computing hash join...  [5.062s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [43.381s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.985s]
Building query seed array...  [2.125s]
Computing hash join...  [5.088s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [40.664s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.052s]
Building query seed array...  [1.913s]
Computing hash join...  [4.925s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [39.907s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.44s]
Building query seed array...  [2.213s]
Computing hash join...  [4.935s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [32.459s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.286s]
Building query seed array...  [2.301s]
Computing hash join...  [4.849s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [35.808s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.984s]
Building query seed array...  [1.965s]
Computing hash join...  [4.823s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [31.172s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.14s]
Clearing query masking...  [1.573s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.52s]
Sorting trace points...  [1.249s]
Computing alignments...  [32.293s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.205s]
Computing alignments...  [32.458s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.21s]
Computing alignments...  [31.86s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.284s]
Computing alignments...  [33.369s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.191s]
Computing alignments...  [33.326s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.291s]
Computing alignments...  [33.629s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.086s]
Sorting trace points...  [0.959s]
Computing alignments...  [33.108s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.253s]
Computing alignments...  [32.806s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.323s]
Computing alignments...  [32.755s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.051s]
Sorting trace points...  [0.932s]
Computing alignments...  [32.657s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.123s]
Computing alignments...  [32.779s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.193s]
Computing alignments...  [32.797s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.273s]
Computing alignments...  [32.978s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.227s]
Sorting trace points...  [1.279s]
Computing alignments...  [33.079s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.018s]
Computing alignments...  [33.077s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.26s]
Computing alignments...  [32.947s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
 [552.918s]
Deallocating reference...  [0.071s]
Loading reference sequences...  [29.858s]
Masking reference...  [30.875s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.809s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.437s]
Building query seed array...  [2.127s]
Computing hash join...  [5.103s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [81.389s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.522s]
Building query seed array...  [2.518s]
Computing hash join...  [5.113s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [53.193s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.11s]
Building query seed array...  [2.578s]
Computing hash join...  [4.974s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [45.753s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.208s]
Building query seed array...  [2.074s]
Computing hash join...  [5.121s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [41.195s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.094s]
Building query seed array...  [1.906s]
Computing hash join...  [4.866s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [42.362s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.362s]
Building query seed array...  [2.22s]
Computing hash join...  [4.892s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [32.78s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.439s]
Building query seed array...  [2.314s]
Computing hash join...  [4.842s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [37.322s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.166s]
Building query seed array...  [1.99s]
Computing hash join...  [4.882s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [29.998s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.509s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.605s]
Sorting trace points...  [1.243s]
Computing alignments...  [32.061s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.136s]
Computing alignments...  [32.116s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.214s]
Computing alignments...  [31.768s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.266s]
Computing alignments...  [33.183s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.242s]
Computing alignments...  [33.349s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.029s]
Sorting trace points...  [0.983s]
Computing alignments...  [33.508s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.106s]
Sorting trace points...  [1.227s]
Computing alignments...  [32.883s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.023s]
Computing alignments...  [32.898s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.22s]
Computing alignments...  [32.86s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.188s]
Computing alignments...  [32.604s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.261s]
Computing alignments...  [32.712s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.261s]
Computing alignments...  [32.761s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.039s]
Sorting trace points...  [1.301s]
Computing alignments...  [32.996s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.262s]
Computing alignments...  [32.967s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.24s]
Computing alignments...  [33.067s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
Sorting trace points...  [0.971s]
Computing alignments...  [32.788s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [552.191s]
Deallocating reference...  [0.072s]
Loading reference sequences...  [29.768s]
Masking reference...  [32.052s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.184s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.551s]
Building query seed array...  [2.133s]
Computing hash join...  [5.096s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [80.635s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.336s]
Building query seed array...  [2.5s]
Computing hash join...  [5.11s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [53.1s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.687s]
Building query seed array...  [2.598s]
Computing hash join...  [5.059s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [45.233s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.374s]
Building query seed array...  [2.132s]
Computing hash join...  [5.131s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [39.813s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.715s]
Building query seed array...  [1.906s]
Computing hash join...  [4.839s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [40.558s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.611s]
Building query seed array...  [2.261s]
Computing hash join...  [4.998s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [33.23s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.487s]
Building query seed array...  [2.37s]
Computing hash join...  [4.839s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [35.447s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.134s]
Building query seed array...  [1.94s]
Computing hash join...  [4.843s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [30.917s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.131s]
Clearing query masking...  [1.623s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.56s]
Sorting trace points...  [1.154s]
Computing alignments...  [32.031s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.305s]
Computing alignments...  [32.214s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.248s]
Computing alignments...  [31.602s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.262s]
Computing alignments...  [33.242s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.267s]
Computing alignments...  [33.208s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.081s]
Sorting trace points...  [0.971s]
Computing alignments...  [33.549s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.077s]
Sorting trace points...  [0.979s]
Computing alignments...  [32.864s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.043s]
Computing alignments...  [32.625s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.236s]
Computing alignments...  [32.605s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.278s]
Computing alignments...  [32.515s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.215s]
Computing alignments...  [32.668s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.268s]
Computing alignments...  [32.659s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.112s]
Sorting trace points...  [1.29s]
Computing alignments...  [32.783s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.245s]
Computing alignments...  [32.865s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.035s]
Sorting trace points...  [1.3s]
Computing alignments...  [32.977s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.237s]
Computing alignments...  [32.848s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0s]
 [550.521s]
Deallocating reference...  [0.076s]
Loading reference sequences...  [29.561s]
Masking reference...  [30.847s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.006s]
Building reference histograms...  [32.136s]
Allocating buffers...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.237s]
Building query seed array...  [2.152s]
Computing hash join...  [5.128s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [81.716s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.221s]
Building query seed array...  [2.318s]
Computing hash join...  [5.051s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [52.06s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.535s]
Building query seed array...  [2.673s]
Computing hash join...  [5.026s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [43.978s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.182s]
Building query seed array...  [2.118s]
Computing hash join...  [5.026s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [39.284s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.176s]
Building query seed array...  [1.993s]
Computing hash join...  [4.891s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [40.759s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.934s]
Building query seed array...  [2.215s]
Computing hash join...  [4.833s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [32.522s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.427s]
Building query seed array...  [2.391s]
Computing hash join...  [4.782s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [36.033s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.938s]
Building query seed array...  [1.883s]
Computing hash join...  [4.908s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [30.955s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.129s]
Clearing query masking...  [1.592s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.463s]
Sorting trace points...  [1.23s]
Computing alignments...  [32.116s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.26s]
Computing alignments...  [32.299s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.077s]
Computing alignments...  [31.733s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.264s]
Computing alignments...  [33.218s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.251s]
Computing alignments...  [33.299s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.277s]
Computing alignments...  [33.699s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.085s]
Sorting trace points...  [1.317s]
Computing alignments...  [32.929s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.185s]
Computing alignments...  [32.824s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.066s]
Sorting trace points...  [0.933s]
Computing alignments...  [32.783s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.089s]
Sorting trace points...  [1.082s]
Computing alignments...  [32.555s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.256s]
Computing alignments...  [32.671s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.248s]
Computing alignments...  [32.649s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.254s]
Computing alignments...  [32.917s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.553s]
Computing alignments...  [33.005s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.238s]
Computing alignments...  [33.079s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
Sorting trace points...  [1.249s]
Computing alignments...  [32.979s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
 [552.306s]
Deallocating reference...  [0.077s]
Loading reference sequences...  [30.695s]
Masking reference...  [32.077s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [31.916s]
Allocating buffers...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.147s]
Building query seed array...  [2.133s]
Computing hash join...  [5.237s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [80.701s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.224s]
Building query seed array...  [2.421s]
Computing hash join...  [5.244s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [52.397s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.42s]
Building query seed array...  [2.638s]
Computing hash join...  [5.215s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [45.757s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.771s]
Building query seed array...  [2.099s]
Computing hash join...  [5.028s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [39.808s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.294s]
Building query seed array...  [1.951s]
Computing hash join...  [4.949s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [39.706s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.464s]
Building query seed array...  [2.214s]
Computing hash join...  [4.963s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [32.949s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.654s]
Building query seed array...  [2.332s]
Computing hash join...  [4.839s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [34.554s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.03s]
Building query seed array...  [1.952s]
Computing hash join...  [4.799s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [30.252s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.121s]
Clearing query masking...  [1.572s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.496s]
Sorting trace points...  [1.115s]
Computing alignments...  [32.204s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.245s]
Computing alignments...  [32.418s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.414s]
Sorting trace points...  [1.181s]
Computing alignments...  [31.714s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.246s]
Computing alignments...  [33.377s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.291s]
Computing alignments...  [33.639s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.281s]
Computing alignments...  [33.72s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.288s]
Computing alignments...  [33.106s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.214s]
Computing alignments...  [33.159s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.044s]
Sorting trace points...  [0.979s]
Computing alignments...  [32.837s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.255s]
Computing alignments...  [32.548s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.018s]
Computing alignments...  [32.648s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.005s]
Computing alignments...  [32.76s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.084s]
Sorting trace points...  [1.096s]
Computing alignments...  [32.89s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.229s]
Computing alignments...  [32.99s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
Sorting trace points...  [1.182s]
Computing alignments...  [32.997s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.244s]
Computing alignments...  [32.975s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [552.97s]
Deallocating reference...  [0.071s]
Loading reference sequences...  [239.99s]
Masking reference...  [31.309s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.098s]
Allocating buffers...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.411s]
Building query seed array...  [2.136s]
Computing hash join...  [5.117s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [81.161s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.183s]
Building query seed array...  [2.487s]
Computing hash join...  [5.073s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [52.637s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.552s]
Building query seed array...  [2.561s]
Computing hash join...  [5.045s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [43.197s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.211s]
Building query seed array...  [2.111s]
Computing hash join...  [5.129s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [40.124s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.061s]
Building query seed array...  [1.909s]
Computing hash join...  [4.85s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [40.175s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.943s]
Building query seed array...  [2.19s]
Computing hash join...  [4.825s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [32.376s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.853s]
Building query seed array...  [2.376s]
Computing hash join...  [4.833s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [35.451s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.729s]
Building query seed array...  [1.98s]
Computing hash join...  [4.882s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [29.81s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.129s]
Clearing query masking...  [1.614s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.389s]
Sorting trace points...  [1.317s]
Computing alignments...  [31.894s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.19s]
Computing alignments...  [32.076s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.025s]
Computing alignments...  [31.624s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.094s]
Sorting trace points...  [1.329s]
Computing alignments...  [33.067s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.001s]
Sorting trace points...  [0.938s]
Computing alignments...  [33.146s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.036s]
Sorting trace points...  [1.242s]
Computing alignments...  [33.315s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.33s]
Sorting trace points...  [1.278s]
Computing alignments...  [32.779s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.301s]
Computing alignments...  [32.6s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.113s]
Sorting trace points...  [1.292s]
Computing alignments...  [32.608s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.278s]
Computing alignments...  [32.508s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.094s]
Sorting trace points...  [1.241s]
Computing alignments...  [32.621s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.089s]
Sorting trace points...  [0.978s]
Computing alignments...  [32.631s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.284s]
Computing alignments...  [32.795s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.475s]
Sorting trace points...  [1.274s]
Computing alignments...  [32.866s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.264s]
Computing alignments...  [32.973s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
Sorting trace points...  [1.268s]
Computing alignments...  [32.747s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
 [550.151s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [29.831s]
Masking reference...  [30.856s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.006s]
Building reference histograms...  [32.267s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.18s]
Building query seed array...  [2.047s]
Computing hash join...  [5.146s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [86.729s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.274s]
Building query seed array...  [2.466s]
Computing hash join...  [5.129s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [54.122s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.145s]
Building query seed array...  [2.66s]
Computing hash join...  [5.047s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [45.72s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.074s]
Building query seed array...  [2.083s]
Computing hash join...  [5.044s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [41.808s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.076s]
Building query seed array...  [2.01s]
Computing hash join...  [4.883s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [40.996s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.086s]
Building query seed array...  [2.222s]
Computing hash join...  [4.928s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [32.448s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.079s]
Building query seed array...  [2.335s]
Computing hash join...  [4.948s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [35.992s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.786s]
Building query seed array...  [1.951s]
Computing hash join...  [4.843s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [30.372s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.632s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.597s]
Sorting trace points...  [1.316s]
Computing alignments...  [32.108s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.244s]
Computing alignments...  [32.231s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.035s]
Sorting trace points...  [1.249s]
Computing alignments...  [31.695s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.282s]
Computing alignments...  [33.205s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.029s]
Computing alignments...  [33.189s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.305s]
Computing alignments...  [33.701s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.077s]
Sorting trace points...  [0.999s]
Computing alignments...  [32.807s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.671s]
Sorting trace points...  [1.261s]
Computing alignments...  [32.899s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.236s]
Computing alignments...  [32.688s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.263s]
Computing alignments...  [32.55s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.035s]
Computing alignments...  [32.668s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.243s]
Computing alignments...  [32.702s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.296s]
Computing alignments...  [32.866s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.088s]
Sorting trace points...  [1.292s]
Computing alignments...  [33.035s]
Deallocating buffers...  [1.529s]
Loading trace points...  [0.561s]
Sorting trace points...  [1.261s]
Computing alignments...  [33.037s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [1.269s]
Computing alignments...  [32.85s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [554.346s]
Deallocating reference...  [0.075s]
Loading reference sequences...  [25.606s]
Masking reference...  [25.492s]
Initializing dictionary...  [0.062s]
Initializing temporary storage...  [0.006s]
Building reference histograms...  [26.421s]
Allocating buffers...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.632s]
Building query seed array...  [2.115s]
Computing hash join...  [4.154s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [65.479s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [9.997s]
Building query seed array...  [2.416s]
Computing hash join...  [4.294s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [43.552s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [11.395s]
Building query seed array...  [2.516s]
Computing hash join...  [4.254s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [36.267s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [8.424s]
Building query seed array...  [2.215s]
Computing hash join...  [4.228s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [33.004s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [8.05s]
Building query seed array...  [1.951s]
Computing hash join...  [4.202s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [34.241s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [10.118s]
Building query seed array...  [2.267s]
Computing hash join...  [4.108s]
Masking low complexity seeds...  [0.198s]
Searching alignments...  [26.8s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [10.706s]
Building query seed array...  [2.412s]
Computing hash join...  [4.152s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [28.791s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [8.085s]
Building query seed array...  [1.976s]
Computing hash join...  [4.126s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [25.403s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.127s]
Clearing query masking...  [1.573s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [11.143s]
Sorting trace points...  [2.011s]
Computing alignments...  [51.217s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.179s]
Sorting trace points...  [2.035s]
Computing alignments...  [51.74s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.056s]
Sorting trace points...  [2.121s]
Computing alignments...  [52.935s]
Deallocating buffers...  [0.036s]
Loading trace points...  [0.14s]
Sorting trace points...  [1.851s]
Computing alignments...  [52.12s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.181s]
Sorting trace points...  [2.037s]
Computing alignments...  [51.773s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.155s]
Sorting trace points...  [2.102s]
Computing alignments...  [51.896s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.128s]
Sorting trace points...  [1.707s]
Computing alignments...  [52.249s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0s]
Sorting trace points...  [1.884s]
Computing alignments...  [52.026s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
 [444.078s]
Deallocating reference...  [0.052s]
Loading reference sequences...  [0.064s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [1933.82s]
 [1933.85s]
Deallocating queries...  [0.059s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [3.999s]
 [5.19s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 18270s
Reported 2374957113 pairwise alignments, 2374957113 HSPs.
13524239 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C17_R1.fastp-trim.20230215.fq.gz complete: C17_R1.blastx.meganized.daa

Now MEGANizing C17_R1.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: C17_R1.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 100% (245.9s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.3s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (4,570.6s)
Total reads:       13,524,239
With hits:          13,524,239 
Alignments:      2,361,870,949
Assig. Taxonomy:    12,661,788
Assig. SEED:           108,671
Assig. EGGNOG:          52,748
Assig. GTDB:           386,410
Assig. EC:           2,107,917
Assig. INTERPRO2GO:  1,198,654
MinSupport set to: 6762
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.5s)
Min-supp. changes:       3,966
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (12.6s)
Min-supp. changes:       2,974
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (31.0s)
Binning reads Syncing
100% (0.4s)
Class. Taxonomy:            74
Class. SEED:               510
Class. EGGNOG:           1,779
Class. GTDB:                20
Class. EC:               2,406
Class. INTERPRO2GO:      8,254
Total time:  4,871s
Peak memory: 35.5 of 195.3G
MEGANization of C17_R1.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C17_R2.fastp-trim.20230215.fq.gz...
b7a27d4f032919be4b2afd9b9915c3e3  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C17_R2.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C17_R2.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.281s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.632s]
Opening the output file...  [0s]
Loading query sequences...  [77.482s]
Masking queries...  [19.6s]
Algorithm: Double-indexed
Building query histograms...  [18.064s]
Loading reference sequences...  [29.39s]
Masking reference...  [31.984s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.02s]
Building reference histograms...  [32.254s]
Allocating buffers...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.522s]
Building query seed array...  [2.107s]
Computing hash join...  [5.291s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [80.193s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.949s]
Building query seed array...  [2.479s]
Computing hash join...  [5.326s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [53.323s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.753s]
Building query seed array...  [2.671s]
Computing hash join...  [5.245s]
Masking low complexity seeds...  [0.269s]
Searching alignments...  [44.43s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.004s]
Building query seed array...  [2.12s]
Computing hash join...  [5.329s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [40.277s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.991s]
Building query seed array...  [1.967s]
Computing hash join...  [5.089s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [44.952s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.617s]
Building query seed array...  [2.255s]
Computing hash join...  [5.113s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [33.012s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.531s]
Building query seed array...  [2.377s]
Computing hash join...  [5.056s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [37.124s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.05s]
Building query seed array...  [2s]
Computing hash join...  [5.03s]
Masking low complexity seeds...  [0.249s]
Searching alignments...  [31.473s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.137s]
Clearing query masking...  [1.631s]
Opening temporary output file...  [0.002s]
Computing alignments... Loading trace points...  [6.699s]
Sorting trace points...  [1.379s]
Computing alignments...  [33.276s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.208s]
Computing alignments...  [32.899s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.074s]
Computing alignments...  [33.15s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.261s]
Computing alignments...  [32.49s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.084s]
Sorting trace points...  [0.931s]
Computing alignments...  [32.701s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.092s]
Sorting trace points...  [1.189s]
Computing alignments...  [31.902s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.218s]
Computing alignments...  [31.695s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.037s]
Computing alignments...  [31.266s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.114s]
Sorting trace points...  [1.231s]
Computing alignments...  [32.538s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.296s]
Computing alignments...  [33.395s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.074s]
Computing alignments...  [33.69s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.316s]
Computing alignments...  [33.444s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.32s]
Computing alignments...  [33.754s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.268s]
Computing alignments...  [33.874s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.073s]
Sorting trace points...  [0.968s]
Computing alignments...  [33.815s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
Sorting trace points...  [1.319s]
Computing alignments...  [34.325s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
 [555.38s]
Deallocating reference...  [0.075s]
Loading reference sequences...  [29.705s]
Masking reference...  [31.89s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.168s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.132s]
Building query seed array...  [2.139s]
Computing hash join...  [5.241s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [79.329s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.323s]
Building query seed array...  [2.495s]
Computing hash join...  [5.191s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [53.157s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.725s]
Building query seed array...  [2.653s]
Computing hash join...  [5.276s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [45.646s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.846s]
Building query seed array...  [2.079s]
Computing hash join...  [5.291s]
Masking low complexity seeds...  [0.27s]
Searching alignments...  [41.104s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.006s]
Building query seed array...  [1.998s]
Computing hash join...  [4.957s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [42.661s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.319s]
Building query seed array...  [2.284s]
Computing hash join...  [5.023s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [33.64s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.339s]
Building query seed array...  [2.35s]
Computing hash join...  [5.026s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [36.469s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.029s]
Building query seed array...  [1.966s]
Computing hash join...  [5.049s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [30.662s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.122s]
Clearing query masking...  [1.655s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.691s]
Sorting trace points...  [1.341s]
Computing alignments...  [33.252s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.257s]
Computing alignments...  [33.097s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.289s]
Computing alignments...  [33.139s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.065s]
Sorting trace points...  [0.951s]
Computing alignments...  [32.575s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.292s]
Computing alignments...  [32.643s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.027s]
Computing alignments...  [31.977s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.229s]
Computing alignments...  [31.577s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.211s]
Computing alignments...  [31.264s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.044s]
Sorting trace points...  [0.929s]
Computing alignments...  [32.712s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.241s]
Computing alignments...  [33.556s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.321s]
Computing alignments...  [33.784s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.317s]
Computing alignments...  [33.541s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.004s]
Computing alignments...  [33.694s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.267s]
Computing alignments...  [33.934s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.285s]
Computing alignments...  [33.773s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [1.085s]
Computing alignments...  [34.231s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
 [555.673s]
Deallocating reference...  [0.078s]
Loading reference sequences...  [29.616s]
Masking reference...  [30.852s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.011s]
Building reference histograms...  [32.984s]
Allocating buffers...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.463s]
Building query seed array...  [2.139s]
Computing hash join...  [5.227s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [80.402s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.52s]
Building query seed array...  [2.471s]
Computing hash join...  [5.232s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [53.321s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.297s]
Building query seed array...  [2.615s]
Computing hash join...  [5.167s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [44.557s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.054s]
Building query seed array...  [2.097s]
Computing hash join...  [5.223s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [40.927s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.26s]
Building query seed array...  [1.946s]
Computing hash join...  [5.108s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [43.67s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.364s]
Building query seed array...  [2.239s]
Computing hash join...  [5.118s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [32.668s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.505s]
Building query seed array...  [2.42s]
Computing hash join...  [5.038s]
Masking low complexity seeds...  [0.249s]
Searching alignments...  [36.504s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.968s]
Building query seed array...  [1.872s]
Computing hash join...  [4.943s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [30.435s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.128s]
Clearing query masking...  [1.65s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.696s]
Sorting trace points...  [1.314s]
Computing alignments...  [33.183s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.225s]
Computing alignments...  [32.869s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.196s]
Computing alignments...  [33.03s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.088s]
Sorting trace points...  [1.123s]
Computing alignments...  [32.508s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.27s]
Computing alignments...  [32.65s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.1s]
Sorting trace points...  [1.208s]
Computing alignments...  [31.934s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.081s]
Sorting trace points...  [0.967s]
Computing alignments...  [31.732s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.179s]
Computing alignments...  [31.416s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.236s]
Computing alignments...  [32.437s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.267s]
Computing alignments...  [33.379s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.096s]
Sorting trace points...  [1.005s]
Computing alignments...  [33.592s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.363s]
Computing alignments...  [33.447s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.058s]
Computing alignments...  [33.665s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.28s]
Computing alignments...  [33.739s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.332s]
Computing alignments...  [33.733s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
Sorting trace points...  [1.297s]
Computing alignments...  [34.186s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [554.837s]
Deallocating reference...  [0.076s]
Loading reference sequences...  [29.489s]
Masking reference...  [32.113s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [31.884s]
Allocating buffers...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.54s]
Building query seed array...  [2.229s]
Computing hash join...  [5.281s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [79.065s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.528s]
Building query seed array...  [2.435s]
Computing hash join...  [5.241s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [53.331s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.149s]
Building query seed array...  [2.651s]
Computing hash join...  [5.269s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [45.048s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.09s]
Building query seed array...  [2.103s]
Computing hash join...  [5.197s]
Masking low complexity seeds...  [0.259s]
Searching alignments...  [41.117s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.789s]
Building query seed array...  [1.966s]
Computing hash join...  [5.032s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [43.357s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.19s]
Building query seed array...  [2.221s]
Computing hash join...  [4.986s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [33.118s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.905s]
Building query seed array...  [2.364s]
Computing hash join...  [5.044s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [35.734s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.687s]
Building query seed array...  [1.936s]
Computing hash join...  [5s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [30.678s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.127s]
Clearing query masking...  [1.57s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [7.357s]
Sorting trace points...  [1.336s]
Computing alignments...  [33.164s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.039s]
Sorting trace points...  [1.041s]
Computing alignments...  [33.025s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.249s]
Computing alignments...  [33.205s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.085s]
Sorting trace points...  [1.202s]
Computing alignments...  [32.655s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.058s]
Sorting trace points...  [0.996s]
Computing alignments...  [32.731s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.093s]
Sorting trace points...  [0.994s]
Computing alignments...  [31.945s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.066s]
Sorting trace points...  [0.986s]
Computing alignments...  [31.611s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.095s]
Computing alignments...  [31.241s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.142s]
Computing alignments...  [32.569s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.039s]
Sorting trace points...  [1.24s]
Computing alignments...  [33.442s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.304s]
Computing alignments...  [33.594s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.286s]
Computing alignments...  [33.52s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.31s]
Computing alignments...  [33.81s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.257s]
Computing alignments...  [33.899s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.289s]
Computing alignments...  [33.885s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [1.281s]
Computing alignments...  [34.187s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0s]
 [556.07s]
Deallocating reference...  [0.08s]
Loading reference sequences...  [31.696s]
Masking reference...  [31.301s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.775s]
Allocating buffers...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.159s]
Building query seed array...  [2.261s]
Computing hash join...  [5.251s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [79.339s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.791s]
Building query seed array...  [2.416s]
Computing hash join...  [5.286s]
Masking low complexity seeds...  [0.267s]
Searching alignments...  [53.441s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.384s]
Building query seed array...  [2.64s]
Computing hash join...  [5.213s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [43.682s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.019s]
Building query seed array...  [2.094s]
Computing hash join...  [5.225s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [39.412s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.922s]
Building query seed array...  [1.849s]
Computing hash join...  [5.019s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [42.581s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.073s]
Building query seed array...  [2.23s]
Computing hash join...  [5.022s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [32.439s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.053s]
Building query seed array...  [2.397s]
Computing hash join...  [4.929s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [35.401s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.233s]
Building query seed array...  [1.931s]
Computing hash join...  [4.979s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [30.789s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.576s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.619s]
Sorting trace points...  [1.321s]
Computing alignments...  [33.145s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.075s]
Sorting trace points...  [0.99s]
Computing alignments...  [32.836s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.141s]
Computing alignments...  [32.946s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.054s]
Sorting trace points...  [0.941s]
Computing alignments...  [32.409s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.219s]
Computing alignments...  [32.746s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.204s]
Computing alignments...  [31.706s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.099s]
Sorting trace points...  [1.186s]
Computing alignments...  [31.535s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.168s]
Computing alignments...  [31.213s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.529s]
Sorting trace points...  [1.245s]
Computing alignments...  [32.554s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.139s]
Computing alignments...  [33.452s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.02s]
Computing alignments...  [33.618s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.273s]
Computing alignments...  [33.413s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.061s]
Sorting trace points...  [0.967s]
Computing alignments...  [33.795s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.287s]
Computing alignments...  [33.941s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.006s]
Computing alignments...  [33.808s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
Sorting trace points...  [1.344s]
Computing alignments...  [34.27s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
 [554.171s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [29.633s]
Masking reference...  [30.868s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.396s]
Allocating buffers...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.242s]
Building query seed array...  [2.118s]
Computing hash join...  [5.194s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [76.869s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.47s]
Building query seed array...  [2.482s]
Computing hash join...  [5.152s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [50.528s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.719s]
Building query seed array...  [2.679s]
Computing hash join...  [5.149s]
Masking low complexity seeds...  [0.272s]
Searching alignments...  [43.73s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.111s]
Building query seed array...  [2.159s]
Computing hash join...  [5.194s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [38.647s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.686s]
Building query seed array...  [1.934s]
Computing hash join...  [4.961s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [41.296s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.212s]
Building query seed array...  [2.269s]
Computing hash join...  [5.058s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [32.431s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.268s]
Building query seed array...  [2.438s]
Computing hash join...  [5.07s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [34.8s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.899s]
Building query seed array...  [1.894s]
Computing hash join...  [5.035s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [29.379s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.626s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.709s]
Sorting trace points...  [1.314s]
Computing alignments...  [32.737s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.072s]
Sorting trace points...  [0.967s]
Computing alignments...  [32.429s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.254s]
Computing alignments...  [32.523s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.23s]
Computing alignments...  [32.125s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.048s]
Sorting trace points...  [0.95s]
Computing alignments...  [32.282s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.224s]
Computing alignments...  [31.534s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.068s]
Sorting trace points...  [0.898s]
Computing alignments...  [31.355s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.097s]
Computing alignments...  [30.93s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.258s]
Computing alignments...  [32.291s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.215s]
Computing alignments...  [32.999s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.091s]
Sorting trace points...  [1.305s]
Computing alignments...  [33.236s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.064s]
Sorting trace points...  [0.933s]
Computing alignments...  [33.132s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.287s]
Computing alignments...  [33.346s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.075s]
Computing alignments...  [33.558s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.271s]
Computing alignments...  [33.55s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.127s]
Computing alignments...  [33.835s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0s]
 [548.151s]
Deallocating reference...  [0.075s]
Loading reference sequences...  [33.96s]
Masking reference...  [31.639s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [31.781s]
Allocating buffers...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.749s]
Building query seed array...  [2.179s]
Computing hash join...  [5.273s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [80.515s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.299s]
Building query seed array...  [2.422s]
Computing hash join...  [5.217s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [53.027s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.641s]
Building query seed array...  [2.645s]
Computing hash join...  [5.125s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [46.543s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.215s]
Building query seed array...  [2.119s]
Computing hash join...  [5.288s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [41.869s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.226s]
Building query seed array...  [1.942s]
Computing hash join...  [5.075s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [43.685s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.222s]
Building query seed array...  [2.242s]
Computing hash join...  [5.072s]
Masking low complexity seeds...  [0.249s]
Searching alignments...  [33.979s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.301s]
Building query seed array...  [2.386s]
Computing hash join...  [5.005s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [36.618s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.983s]
Building query seed array...  [1.925s]
Computing hash join...  [5.048s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [30.767s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.139s]
Clearing query masking...  [1.641s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.696s]
Sorting trace points...  [1.325s]
Computing alignments...  [33.193s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.158s]
Computing alignments...  [32.798s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.253s]
Computing alignments...  [33.02s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.097s]
Sorting trace points...  [1.276s]
Computing alignments...  [32.466s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.236s]
Computing alignments...  [32.794s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.755s]
Sorting trace points...  [1.233s]
Computing alignments...  [31.972s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.199s]
Computing alignments...  [31.646s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.176s]
Computing alignments...  [31.553s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.012s]
Computing alignments...  [32.611s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.292s]
Computing alignments...  [33.433s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.092s]
Sorting trace points...  [1.313s]
Computing alignments...  [33.695s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.249s]
Computing alignments...  [33.593s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.351s]
Sorting trace points...  [1.284s]
Computing alignments...  [33.697s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.324s]
Computing alignments...  [33.974s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.163s]
Computing alignments...  [33.798s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
Sorting trace points...  [1.049s]
Computing alignments...  [34.136s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
 [556.887s]
Deallocating reference...  [0.079s]
Loading reference sequences...  [31.958s]
Masking reference...  [30.826s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.615s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.627s]
Building query seed array...  [2.143s]
Computing hash join...  [5.288s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [79.774s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.321s]
Building query seed array...  [2.445s]
Computing hash join...  [5.279s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [54.746s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.28s]
Building query seed array...  [2.628s]
Computing hash join...  [5.192s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [44.268s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.164s]
Building query seed array...  [2.086s]
Computing hash join...  [5.143s]
Masking low complexity seeds...  [0.268s]
Searching alignments...  [40.065s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.055s]
Building query seed array...  [1.965s]
Computing hash join...  [5.046s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [42.429s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.031s]
Building query seed array...  [2.255s]
Computing hash join...  [4.97s]
Masking low complexity seeds...  [0.249s]
Searching alignments...  [32.891s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.087s]
Building query seed array...  [2.433s]
Computing hash join...  [5.02s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [35.385s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.916s]
Building query seed array...  [1.925s]
Computing hash join...  [4.958s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [29.967s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.615s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.893s]
Sorting trace points...  [1.017s]
Computing alignments...  [33.052s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.216s]
Computing alignments...  [32.84s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.143s]
Computing alignments...  [32.951s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.229s]
Computing alignments...  [32.369s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.064s]
Sorting trace points...  [0.981s]
Computing alignments...  [32.501s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.221s]
Computing alignments...  [31.768s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.779s]
Sorting trace points...  [1.236s]
Computing alignments...  [31.637s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.217s]
Computing alignments...  [31.262s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.272s]
Computing alignments...  [32.574s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.276s]
Computing alignments...  [33.374s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.293s]
Computing alignments...  [33.572s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.038s]
Sorting trace points...  [0.944s]
Computing alignments...  [33.411s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.318s]
Computing alignments...  [33.681s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.346s]
Sorting trace points...  [1.302s]
Computing alignments...  [33.806s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.059s]
Sorting trace points...  [0.967s]
Computing alignments...  [33.766s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
Sorting trace points...  [1.307s]
Computing alignments...  [34.232s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
 [554.868s]
Deallocating reference...  [0.08s]
Loading reference sequences...  [29.91s]
Masking reference...  [30.889s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.672s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.377s]
Building query seed array...  [2.116s]
Computing hash join...  [5.288s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [78.099s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.486s]
Building query seed array...  [2.509s]
Computing hash join...  [5.253s]
Masking low complexity seeds...  [0.272s]
Searching alignments...  [52.748s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.483s]
Building query seed array...  [2.668s]
Computing hash join...  [5.257s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [45.165s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.238s]
Building query seed array...  [2.094s]
Computing hash join...  [5.344s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [41.144s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.081s]
Building query seed array...  [1.961s]
Computing hash join...  [4.991s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [42.28s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.601s]
Building query seed array...  [2.222s]
Computing hash join...  [5.033s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [32.987s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.302s]
Building query seed array...  [2.4s]
Computing hash join...  [4.951s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [37.241s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.084s]
Building query seed array...  [2.005s]
Computing hash join...  [4.955s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [30.799s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.558s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.736s]
Sorting trace points...  [1.31s]
Computing alignments...  [33.155s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.145s]
Computing alignments...  [32.856s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.064s]
Sorting trace points...  [0.965s]
Computing alignments...  [33.039s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.169s]
Computing alignments...  [32.635s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.244s]
Computing alignments...  [32.778s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.154s]
Computing alignments...  [32.051s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.213s]
Computing alignments...  [31.678s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.052s]
Sorting trace points...  [0.992s]
Computing alignments...  [31.317s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.161s]
Computing alignments...  [32.644s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.274s]
Computing alignments...  [33.474s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.279s]
Computing alignments...  [33.634s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.042s]
Sorting trace points...  [1.148s]
Computing alignments...  [33.503s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.036s]
Sorting trace points...  [1.216s]
Computing alignments...  [33.757s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.289s]
Computing alignments...  [33.826s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.308s]
Computing alignments...  [33.734s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.249s]
Computing alignments...  [34.132s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [555.288s]
Deallocating reference...  [0.078s]
Loading reference sequences...  [29.499s]
Masking reference...  [30.841s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.662s]
Allocating buffers...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.323s]
Building query seed array...  [2.089s]
Computing hash join...  [5.206s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [76.408s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.469s]
Building query seed array...  [2.594s]
Computing hash join...  [5.237s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [54.29s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [14.045s]
Building query seed array...  [2.657s]
Computing hash join...  [5.136s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [46.822s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.147s]
Building query seed array...  [2.077s]
Computing hash join...  [5.182s]
Masking low complexity seeds...  [0.265s]
Searching alignments...  [39.946s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.148s]
Building query seed array...  [1.98s]
Computing hash join...  [4.993s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [43.106s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.139s]
Building query seed array...  [2.256s]
Computing hash join...  [4.958s]
Masking low complexity seeds...  [0.259s]
Searching alignments...  [32.519s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.351s]
Building query seed array...  [2.322s]
Computing hash join...  [5.016s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [36.973s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.847s]
Building query seed array...  [1.968s]
Computing hash join...  [5.04s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [31.015s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.566s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.712s]
Sorting trace points...  [1.312s]
Computing alignments...  [33.14s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.456s]
Sorting trace points...  [1.283s]
Computing alignments...  [32.98s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.111s]
Computing alignments...  [33.051s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.257s]
Computing alignments...  [32.601s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.079s]
Sorting trace points...  [0.965s]
Computing alignments...  [32.752s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.078s]
Sorting trace points...  [0.939s]
Computing alignments...  [31.976s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.191s]
Computing alignments...  [31.747s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.193s]
Computing alignments...  [31.35s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.248s]
Computing alignments...  [32.635s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.164s]
Computing alignments...  [33.59s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.295s]
Computing alignments...  [33.734s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.064s]
Sorting trace points...  [0.981s]
Computing alignments...  [33.434s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.077s]
Sorting trace points...  [0.978s]
Computing alignments...  [33.728s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.279s]
Computing alignments...  [33.803s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.029s]
Computing alignments...  [33.863s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [1.013s]
Computing alignments...  [34.293s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
 [555.411s]
Deallocating reference...  [0.076s]
Loading reference sequences...  [30.212s]
Masking reference...  [32.076s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.439s]
Allocating buffers...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.321s]
Building query seed array...  [2.103s]
Computing hash join...  [5.235s]
Masking low complexity seeds...  [0.266s]
Searching alignments...  [77.695s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.029s]
Building query seed array...  [2.601s]
Computing hash join...  [5.32s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [53.265s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.589s]
Building query seed array...  [2.621s]
Computing hash join...  [5.236s]
Masking low complexity seeds...  [0.269s]
Searching alignments...  [43.698s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.325s]
Building query seed array...  [2.078s]
Computing hash join...  [5.132s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [38.201s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.138s]
Building query seed array...  [1.917s]
Computing hash join...  [4.972s]
Masking low complexity seeds...  [0.259s]
Searching alignments...  [41.918s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.72s]
Building query seed array...  [2.205s]
Computing hash join...  [5.108s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [32.813s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.199s]
Building query seed array...  [2.338s]
Computing hash join...  [4.999s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [35.683s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.766s]
Building query seed array...  [1.961s]
Computing hash join...  [5.041s]
Masking low complexity seeds...  [0.259s]
Searching alignments...  [30.366s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.616s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.623s]
Sorting trace points...  [1.315s]
Computing alignments...  [33.414s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.252s]
Computing alignments...  [33.257s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.039s]
Sorting trace points...  [1.285s]
Computing alignments...  [33.769s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.173s]
Computing alignments...  [32.857s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.21s]
Computing alignments...  [33.065s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.179s]
Computing alignments...  [32.445s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.249s]
Computing alignments...  [31.586s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.156s]
Computing alignments...  [31.395s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.213s]
Computing alignments...  [32.635s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.291s]
Computing alignments...  [33.415s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.094s]
Computing alignments...  [33.681s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.285s]
Computing alignments...  [33.448s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.249s]
Sorting trace points...  [1.292s]
Computing alignments...  [33.674s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.04s]
Sorting trace points...  [1.257s]
Computing alignments...  [34.259s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.1s]
Computing alignments...  [34.01s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
Sorting trace points...  [1.255s]
Computing alignments...  [34.379s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0s]
 [558.83s]
Deallocating reference...  [0.082s]
Loading reference sequences...  [29.179s]
Masking reference...  [30.859s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [33.766s]
Allocating buffers...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [9.92s]
Building query seed array...  [2.09s]
Computing hash join...  [5.17s]
Masking low complexity seeds...  [0.265s]
Searching alignments...  [80.274s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.504s]
Building query seed array...  [2.433s]
Computing hash join...  [5.205s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [54.177s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.115s]
Building query seed array...  [2.716s]
Computing hash join...  [5.231s]
Masking low complexity seeds...  [0.269s]
Searching alignments...  [45.415s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.114s]
Building query seed array...  [2.121s]
Computing hash join...  [5.249s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [40.072s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.849s]
Building query seed array...  [1.899s]
Computing hash join...  [4.972s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [42.971s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.228s]
Building query seed array...  [2.261s]
Computing hash join...  [4.999s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [33.135s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.226s]
Building query seed array...  [2.351s]
Computing hash join...  [5.034s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [37.848s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.145s]
Building query seed array...  [1.961s]
Computing hash join...  [5.032s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [31.516s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.14s]
Clearing query masking...  [1.577s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.636s]
Sorting trace points...  [1.32s]
Computing alignments...  [32.928s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.028s]
Computing alignments...  [32.662s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.037s]
Computing alignments...  [32.95s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.245s]
Computing alignments...  [32.157s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.228s]
Computing alignments...  [32.462s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.24s]
Computing alignments...  [31.949s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.065s]
Sorting trace points...  [0.952s]
Computing alignments...  [31.61s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.199s]
Computing alignments...  [31.461s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.125s]
Computing alignments...  [32.542s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.264s]
Computing alignments...  [33.498s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.089s]
Sorting trace points...  [1.073s]
Computing alignments...  [33.609s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.088s]
Computing alignments...  [33.426s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.062s]
Computing alignments...  [33.589s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.346s]
Computing alignments...  [33.773s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.315s]
Computing alignments...  [33.72s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [1.293s]
Computing alignments...  [34.252s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [553.307s]
Deallocating reference...  [0.084s]
Loading reference sequences...  [32.522s]
Masking reference...  [31.171s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.733s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.3s]
Building query seed array...  [2.232s]
Computing hash join...  [5.223s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [80.365s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.952s]
Building query seed array...  [2.459s]
Computing hash join...  [5.309s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [53.01s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.613s]
Building query seed array...  [2.598s]
Computing hash join...  [5.215s]
Masking low complexity seeds...  [0.259s]
Searching alignments...  [45.158s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.092s]
Building query seed array...  [2.113s]
Computing hash join...  [5.157s]
Masking low complexity seeds...  [0.256s]
Searching alignments...  [40.557s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.082s]
Building query seed array...  [1.893s]
Computing hash join...  [4.999s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [43.948s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.32s]
Building query seed array...  [2.223s]
Computing hash join...  [5.036s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [32.64s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.949s]
Building query seed array...  [2.422s]
Computing hash join...  [5.067s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [37.157s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.852s]
Building query seed array...  [1.938s]
Computing hash join...  [4.972s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [30.357s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.13s]
Clearing query masking...  [1.588s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.826s]
Sorting trace points...  [1.32s]
Computing alignments...  [33.109s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.254s]
Computing alignments...  [32.855s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.074s]
Computing alignments...  [33.321s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.245s]
Computing alignments...  [32.645s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.059s]
Computing alignments...  [32.753s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.083s]
Sorting trace points...  [0.907s]
Computing alignments...  [32.057s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.088s]
Sorting trace points...  [1.195s]
Computing alignments...  [31.703s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.194s]
Computing alignments...  [31.476s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.054s]
Sorting trace points...  [0.942s]
Computing alignments...  [32.535s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.285s]
Computing alignments...  [33.345s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.182s]
Computing alignments...  [33.546s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.42s]
Computing alignments...  [33.396s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.312s]
Computing alignments...  [33.762s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.279s]
Computing alignments...  [33.89s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.315s]
Computing alignments...  [33.7s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [1.205s]
Computing alignments...  [34.201s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
 [555.736s]
Deallocating reference...  [0.077s]
Loading reference sequences...  [23.947s]
Masking reference...  [25.978s]
Initializing dictionary...  [0.063s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [26.059s]
Allocating buffers...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.634s]
Building query seed array...  [2.014s]
Computing hash join...  [4.301s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [63.473s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [9.958s]
Building query seed array...  [2.541s]
Computing hash join...  [4.351s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [42.88s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [11.238s]
Building query seed array...  [2.69s]
Computing hash join...  [4.311s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [36.974s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [8.032s]
Building query seed array...  [2.196s]
Computing hash join...  [4.356s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [34.345s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [8.357s]
Building query seed array...  [2.002s]
Computing hash join...  [4.216s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [36.471s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [10.394s]
Building query seed array...  [2.281s]
Computing hash join...  [4.185s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [26.864s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [10.937s]
Building query seed array...  [2.43s]
Computing hash join...  [4.222s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [29.518s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [7.958s]
Building query seed array...  [1.919s]
Computing hash join...  [4.162s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [25.917s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.106s]
Clearing query masking...  [1.541s]
Opening temporary output file...  [0.002s]
Computing alignments... Loading trace points...  [11.349s]
Sorting trace points...  [2.07s]
Computing alignments...  [52.377s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.125s]
Sorting trace points...  [1.868s]
Computing alignments...  [51.894s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.16s]
Sorting trace points...  [2.015s]
Computing alignments...  [51.174s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0.155s]
Sorting trace points...  [1.997s]
Computing alignments...  [50.214s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.145s]
Sorting trace points...  [2.095s]
Computing alignments...  [52.532s]
Deallocating buffers...  [0.036s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.639s]
Computing alignments...  [53.469s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.063s]
Sorting trace points...  [2.173s]
Computing alignments...  [53.899s]
Deallocating buffers...  [0.032s]
Loading trace points...  [0s]
Sorting trace points...  [1.63s]
Computing alignments...  [53.761s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0s]
 [447.293s]
Deallocating reference...  [0.052s]
Loading reference sequences...  [0.088s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [1923.06s]
 [1923.06s]
Deallocating queries...  [0.054s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [3.946s]
 [5.091s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 18138.7s
Reported 2297365947 pairwise alignments, 2297365947 HSPs.
13880422 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C17_R2.fastp-trim.20230215.fq.gz complete: C17_R2.blastx.meganized.daa

Now MEGANizing C17_R2.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: C17_R2.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 100% (284.3s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.2s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (4,294.4s)
Total reads:       13,880,422
With hits:          13,880,422 
Alignments:      2,286,392,247
Assig. Taxonomy:    12,943,662
Assig. SEED:           105,479
Assig. EGGNOG:          52,877
Assig. GTDB:           372,309
Assig. EC:           2,142,765
Assig. INTERPRO2GO:  1,188,863
MinSupport set to: 6940
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.5s)
Min-supp. changes:       4,163
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (9.5s)
Min-supp. changes:       3,054
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (30.8s)
Binning reads Syncing
100% (0.4s)
Class. Taxonomy:            83
Class. SEED:               496
Class. EGGNOG:           1,795
Class. GTDB:                17
Class. EC:               2,414
Class. INTERPRO2GO:      8,330
Total time:  4,629s
Peak memory: 33.1 of 195.3G
MEGANization of C17_R2.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C18_R1.fastp-trim.20230215.fq.gz...
7afcd5d963bcfa35aa049f36f7faf51b  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C18_R1.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C18_R1.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.311s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.716s]
Opening the output file...  [0s]
Loading query sequences...  [71.079s]
Masking queries...  [17.771s]
Algorithm: Double-indexed
Building query histograms...  [19.278s]
Loading reference sequences...  [29.403s]
Masking reference...  [32.097s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.084s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.143s]
Building query seed array...  [1.836s]
Computing hash join...  [5.17s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [77.774s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.16s]
Building query seed array...  [2.28s]
Computing hash join...  [5.002s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [50.039s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.55s]
Building query seed array...  [2.33s]
Computing hash join...  [4.983s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [44.123s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.114s]
Building query seed array...  [1.889s]
Computing hash join...  [5.106s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [39.163s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.99s]
Building query seed array...  [1.851s]
Computing hash join...  [4.831s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [38.355s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.301s]
Building query seed array...  [2.05s]
Computing hash join...  [4.867s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [31.255s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.567s]
Building query seed array...  [2.166s]
Computing hash join...  [4.781s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [33.893s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.214s]
Building query seed array...  [1.711s]
Computing hash join...  [4.903s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [28.525s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.128s]
Clearing query masking...  [1.493s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.778s]
Sorting trace points...  [1.014s]
Computing alignments...  [32.395s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.062s]
Sorting trace points...  [0.966s]
Computing alignments...  [32.028s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.24s]
Computing alignments...  [32.424s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.045s]
Sorting trace points...  [0.993s]
Computing alignments...  [31.754s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.155s]
Computing alignments...  [31.493s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.045s]
Computing alignments...  [31.104s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.182s]
Computing alignments...  [30.73s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.112s]
Sorting trace points...  [0.897s]
Computing alignments...  [30.353s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.14s]
Computing alignments...  [30.59s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.023s]
Computing alignments...  [31.257s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.201s]
Computing alignments...  [31.226s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.026s]
Computing alignments...  [31.505s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.18s]
Computing alignments...  [31.282s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.151s]
Computing alignments...  [31.469s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.118s]
Computing alignments...  [31.505s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [0.887s]
Computing alignments...  [30.997s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [527.31s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [33.384s]
Masking reference...  [31.318s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.622s]
Allocating buffers...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.312s]
Building query seed array...  [1.929s]
Computing hash join...  [5.04s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [76.576s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.806s]
Building query seed array...  [2.225s]
Computing hash join...  [5.011s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [47.515s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.486s]
Building query seed array...  [2.469s]
Computing hash join...  [4.905s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [40.744s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.067s]
Building query seed array...  [1.951s]
Computing hash join...  [4.957s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [37.296s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.913s]
Building query seed array...  [1.788s]
Computing hash join...  [4.876s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [37.359s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.028s]
Building query seed array...  [2.105s]
Computing hash join...  [4.845s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [29.967s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.107s]
Building query seed array...  [2.223s]
Computing hash join...  [4.846s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [34.011s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.67s]
Building query seed array...  [1.74s]
Computing hash join...  [4.94s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [28.692s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.122s]
Clearing query masking...  [1.51s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.526s]
Sorting trace points...  [1.239s]
Computing alignments...  [32.01s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.018s]
Computing alignments...  [31.762s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.198s]
Computing alignments...  [32.209s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.441s]
Sorting trace points...  [1.208s]
Computing alignments...  [31.57s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.081s]
Computing alignments...  [31.281s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.001s]
Sorting trace points...  [0.939s]
Computing alignments...  [30.911s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.195s]
Computing alignments...  [30.58s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.066s]
Sorting trace points...  [0.968s]
Computing alignments...  [30.164s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.147s]
Computing alignments...  [30.34s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.165s]
Computing alignments...  [31.038s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.156s]
Computing alignments...  [31.009s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.087s]
Sorting trace points...  [1.168s]
Computing alignments...  [31.095s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.093s]
Sorting trace points...  [1.142s]
Computing alignments...  [31.036s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.223s]
Computing alignments...  [31.217s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.053s]
Computing alignments...  [31.315s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.148s]
Computing alignments...  [30.967s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
 [524.75s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [30.974s]
Masking reference...  [31.805s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.48s]
Allocating buffers...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.663s]
Building query seed array...  [1.937s]
Computing hash join...  [5.026s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [77.472s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.525s]
Building query seed array...  [2.288s]
Computing hash join...  [5.049s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [48.878s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.546s]
Building query seed array...  [2.444s]
Computing hash join...  [4.962s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [43.543s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.999s]
Building query seed array...  [2.001s]
Computing hash join...  [4.984s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [39.531s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.177s]
Building query seed array...  [1.787s]
Computing hash join...  [4.929s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [38.01s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.372s]
Building query seed array...  [2.028s]
Computing hash join...  [4.73s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [31.469s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.48s]
Building query seed array...  [2.177s]
Computing hash join...  [4.786s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [34.807s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.805s]
Building query seed array...  [1.782s]
Computing hash join...  [4.804s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [29.055s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.13s]
Clearing query masking...  [1.517s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.471s]
Sorting trace points...  [1.294s]
Computing alignments...  [32.097s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.078s]
Computing alignments...  [32.261s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.275s]
Computing alignments...  [32.244s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.226s]
Computing alignments...  [31.61s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.21s]
Computing alignments...  [31.453s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.188s]
Computing alignments...  [31.043s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.2s]
Computing alignments...  [30.77s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.03s]
Computing alignments...  [30.188s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.152s]
Computing alignments...  [30.589s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.172s]
Computing alignments...  [31.285s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.105s]
Sorting trace points...  [1.064s]
Computing alignments...  [31.083s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.206s]
Computing alignments...  [31.49s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.135s]
Computing alignments...  [31.274s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [0.908s]
Computing alignments...  [31.411s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.224s]
Computing alignments...  [31.393s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.147s]
Computing alignments...  [30.936s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [527.359s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [29.885s]
Masking reference...  [30.82s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [33.541s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.263s]
Building query seed array...  [1.942s]
Computing hash join...  [5.032s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [77.966s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.481s]
Building query seed array...  [2.25s]
Computing hash join...  [5.086s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [47.342s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.494s]
Building query seed array...  [2.427s]
Computing hash join...  [4.951s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [41.657s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.448s]
Building query seed array...  [1.893s]
Computing hash join...  [4.955s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [37.488s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.087s]
Building query seed array...  [1.812s]
Computing hash join...  [4.794s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [38.052s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.165s]
Building query seed array...  [2.065s]
Computing hash join...  [4.797s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [30.412s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.887s]
Building query seed array...  [2.174s]
Computing hash join...  [4.793s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [34.3s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.348s]
Building query seed array...  [1.771s]
Computing hash join...  [4.79s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [28.841s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.526s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.541s]
Sorting trace points...  [1.27s]
Computing alignments...  [32.034s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.044s]
Computing alignments...  [32.362s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.113s]
Computing alignments...  [32.289s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.197s]
Computing alignments...  [31.625s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.2s]
Computing alignments...  [31.408s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.015s]
Computing alignments...  [31.015s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.15s]
Computing alignments...  [30.669s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.171s]
Computing alignments...  [30.322s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.1s]
Sorting trace points...  [1.175s]
Computing alignments...  [30.52s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.085s]
Sorting trace points...  [1.186s]
Computing alignments...  [31.155s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.216s]
Sorting trace points...  [1.19s]
Computing alignments...  [31.052s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.081s]
Sorting trace points...  [0.885s]
Computing alignments...  [31.412s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.156s]
Computing alignments...  [31.251s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.219s]
Computing alignments...  [31.394s]
Deallocating buffers...  [0.021s]
Loading trace points...  [1.016s]
Sorting trace points...  [1.202s]
Computing alignments...  [31.462s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.19s]
Computing alignments...  [30.972s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [528.253s]
Deallocating reference...  [0.066s]
Loading reference sequences...  [29.491s]
Masking reference...  [30.85s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [33.336s]
Allocating buffers...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.424s]
Building query seed array...  [1.924s]
Computing hash join...  [4.96s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [75.46s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.743s]
Building query seed array...  [2.367s]
Computing hash join...  [4.983s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [49.209s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.256s]
Building query seed array...  [2.397s]
Computing hash join...  [5.048s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [42.169s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.144s]
Building query seed array...  [1.945s]
Computing hash join...  [4.998s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [38.68s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.956s]
Building query seed array...  [1.846s]
Computing hash join...  [4.79s]
Masking low complexity seeds...  [0.199s]
Searching alignments...  [38.303s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.597s]
Building query seed array...  [2.082s]
Computing hash join...  [4.844s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [31.542s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.375s]
Building query seed array...  [2.199s]
Computing hash join...  [4.787s]
Masking low complexity seeds...  [0.2s]
Searching alignments...  [34.395s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.888s]
Building query seed array...  [1.761s]
Computing hash join...  [4.841s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [28.263s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.13s]
Clearing query masking...  [1.538s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.54s]
Sorting trace points...  [1.242s]
Computing alignments...  [32.044s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.208s]
Computing alignments...  [31.769s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.233s]
Computing alignments...  [32.271s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.178s]
Computing alignments...  [31.582s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.152s]
Computing alignments...  [31.401s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.191s]
Computing alignments...  [30.912s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.184s]
Computing alignments...  [30.557s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.092s]
Sorting trace points...  [1.121s]
Computing alignments...  [30.14s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.086s]
Computing alignments...  [30.429s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.224s]
Computing alignments...  [31.063s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.191s]
Computing alignments...  [31.067s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.164s]
Computing alignments...  [31.349s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.002s]
Sorting trace points...  [1.069s]
Computing alignments...  [31.043s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.198s]
Computing alignments...  [31.34s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.184s]
Computing alignments...  [31.391s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.19s]
Computing alignments...  [30.85s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [525.78s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [32.434s]
Masking reference...  [31.15s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.7s]
Allocating buffers...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [9.97s]
Building query seed array...  [1.997s]
Computing hash join...  [5.048s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [74.559s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.97s]
Building query seed array...  [2.292s]
Computing hash join...  [5.001s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [47.238s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.406s]
Building query seed array...  [2.363s]
Computing hash join...  [5.035s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [40.595s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.046s]
Building query seed array...  [1.936s]
Computing hash join...  [4.992s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [37.002s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.074s]
Building query seed array...  [1.737s]
Computing hash join...  [4.828s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [36.976s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.406s]
Building query seed array...  [2.038s]
Computing hash join...  [4.921s]
Masking low complexity seeds...  [0.72s]
Searching alignments...  [30.841s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.655s]
Building query seed array...  [2.184s]
Computing hash join...  [4.82s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [32.963s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.126s]
Building query seed array...  [1.818s]
Computing hash join...  [4.813s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [28.286s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.13s]
Clearing query masking...  [1.533s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.437s]
Sorting trace points...  [1.255s]
Computing alignments...  [31.854s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.056s]
Computing alignments...  [31.276s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.042s]
Sorting trace points...  [1.209s]
Computing alignments...  [31.763s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.219s]
Computing alignments...  [31.288s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.183s]
Computing alignments...  [30.946s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.07s]
Sorting trace points...  [0.885s]
Computing alignments...  [30.625s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.174s]
Computing alignments...  [30.343s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.169s]
Computing alignments...  [29.948s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.137s]
Computing alignments...  [30.194s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.074s]
Sorting trace points...  [0.949s]
Computing alignments...  [30.926s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.227s]
Sorting trace points...  [1.184s]
Computing alignments...  [30.841s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.22s]
Computing alignments...  [30.985s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.173s]
Computing alignments...  [30.886s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.198s]
Computing alignments...  [31.072s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.087s]
Sorting trace points...  [0.947s]
Computing alignments...  [31.158s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.121s]
Computing alignments...  [30.693s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
 [520.681s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [32.542s]
Masking reference...  [30.899s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.918s]
Allocating buffers...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [9.943s]
Building query seed array...  [1.9s]
Computing hash join...  [5.05s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [77.391s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.249s]
Building query seed array...  [2.303s]
Computing hash join...  [4.989s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [48.817s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.73s]
Building query seed array...  [2.355s]
Computing hash join...  [4.946s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [41.87s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.193s]
Building query seed array...  [1.904s]
Computing hash join...  [4.973s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [39.638s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.771s]
Building query seed array...  [1.807s]
Computing hash join...  [4.812s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [39.814s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.279s]
Building query seed array...  [2.022s]
Computing hash join...  [4.802s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [30.45s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.136s]
Building query seed array...  [2.235s]
Computing hash join...  [4.845s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [33.964s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.107s]
Building query seed array...  [1.797s]
Computing hash join...  [4.779s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [28.456s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.118s]
Clearing query masking...  [1.533s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.493s]
Sorting trace points...  [1.284s]
Computing alignments...  [32.062s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.132s]
Sorting trace points...  [1.214s]
Computing alignments...  [32.108s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.23s]
Computing alignments...  [32.129s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.18s]
Computing alignments...  [31.574s]
Deallocating buffers...  [0.017s]
Loading trace points...  [1.303s]
Sorting trace points...  [0.995s]
Computing alignments...  [31.497s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.074s]
Sorting trace points...  [0.991s]
Computing alignments...  [30.983s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.146s]
Computing alignments...  [30.646s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.159s]
Computing alignments...  [30.179s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.171s]
Computing alignments...  [30.547s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.171s]
Computing alignments...  [31.147s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.158s]
Computing alignments...  [31.062s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.195s]
Computing alignments...  [31.152s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.04s]
Sorting trace points...  [0.996s]
Computing alignments...  [31.191s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.184s]
Computing alignments...  [31.338s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.098s]
Sorting trace points...  [1.202s]
Computing alignments...  [31.358s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.075s]
Computing alignments...  [30.947s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [527.305s]
Deallocating reference...  [0.064s]
Loading reference sequences...  [29.463s]
Masking reference...  [32.101s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.763s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.178s]
Building query seed array...  [1.976s]
Computing hash join...  [5.086s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [77.231s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.763s]
Building query seed array...  [2.225s]
Computing hash join...  [5.022s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [50.183s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.464s]
Building query seed array...  [2.402s]
Computing hash join...  [4.979s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [41.641s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.041s]
Building query seed array...  [1.917s]
Computing hash join...  [5.037s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [37.454s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.905s]
Building query seed array...  [1.805s]
Computing hash join...  [4.767s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [38.642s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.627s]
Building query seed array...  [2.064s]
Computing hash join...  [4.834s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [30.358s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.03s]
Building query seed array...  [2.11s]
Computing hash join...  [4.746s]
Masking low complexity seeds...  [0.2s]
Searching alignments...  [34.094s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.066s]
Building query seed array...  [1.772s]
Computing hash join...  [4.766s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [28.746s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.139s]
Clearing query masking...  [1.54s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.513s]
Sorting trace points...  [1.293s]
Computing alignments...  [31.987s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.223s]
Computing alignments...  [31.922s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.232s]
Computing alignments...  [32.211s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.23s]
Computing alignments...  [31.646s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.071s]
Computing alignments...  [31.451s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.194s]
Computing alignments...  [31.064s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.195s]
Computing alignments...  [30.745s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.156s]
Computing alignments...  [30.299s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.174s]
Computing alignments...  [30.525s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.215s]
Computing alignments...  [31.276s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.199s]
Computing alignments...  [31.166s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.064s]
Computing alignments...  [31.527s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.218s]
Computing alignments...  [31.189s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.001s]
Sorting trace points...  [0.983s]
Computing alignments...  [31.457s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.178s]
Computing alignments...  [31.524s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.173s]
Computing alignments...  [31.075s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
 [527.492s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [29.537s]
Masking reference...  [30.838s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [33.004s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.307s]
Building query seed array...  [1.956s]
Computing hash join...  [5.029s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [76.705s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.659s]
Building query seed array...  [2.287s]
Computing hash join...  [5.036s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [48.756s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.031s]
Building query seed array...  [2.45s]
Computing hash join...  [4.936s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [42.926s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.894s]
Building query seed array...  [1.943s]
Computing hash join...  [4.898s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [38.464s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.906s]
Building query seed array...  [1.813s]
Computing hash join...  [4.871s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [37.895s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.081s]
Building query seed array...  [2.045s]
Computing hash join...  [4.759s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [30.322s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.242s]
Building query seed array...  [2.225s]
Computing hash join...  [4.85s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [34.368s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.889s]
Building query seed array...  [1.787s]
Computing hash join...  [4.918s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [29.179s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.14s]
Clearing query masking...  [1.51s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.548s]
Sorting trace points...  [1.251s]
Computing alignments...  [31.98s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.234s]
Sorting trace points...  [1.224s]
Computing alignments...  [32.094s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.23s]
Computing alignments...  [32.072s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [0.956s]
Computing alignments...  [31.838s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.152s]
Computing alignments...  [31.351s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.036s]
Sorting trace points...  [1.173s]
Computing alignments...  [30.965s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.158s]
Computing alignments...  [30.568s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.118s]
Sorting trace points...  [1.175s]
Computing alignments...  [30.182s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.099s]
Sorting trace points...  [1.186s]
Computing alignments...  [30.428s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.17s]
Computing alignments...  [31.253s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.069s]
Sorting trace points...  [0.941s]
Computing alignments...  [31.153s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.191s]
Computing alignments...  [31.418s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.17s]
Computing alignments...  [31.188s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.21s]
Computing alignments...  [31.292s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.068s]
Sorting trace points...  [0.936s]
Computing alignments...  [31.361s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [0.948s]
Computing alignments...  [30.892s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [526.061s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.615s]
Masking reference...  [30.828s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [33.193s]
Allocating buffers...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.182s]
Building query seed array...  [1.954s]
Computing hash join...  [4.97s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [79.287s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.384s]
Building query seed array...  [2.176s]
Computing hash join...  [4.996s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [49.735s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.048s]
Building query seed array...  [2.437s]
Computing hash join...  [5.006s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [41.627s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.15s]
Building query seed array...  [1.966s]
Computing hash join...  [5.037s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [37.456s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.789s]
Building query seed array...  [1.883s]
Computing hash join...  [4.957s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [37.91s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.107s]
Building query seed array...  [2.05s]
Computing hash join...  [4.788s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [30.855s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.873s]
Building query seed array...  [2.192s]
Computing hash join...  [4.848s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [34.417s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.782s]
Building query seed array...  [1.761s]
Computing hash join...  [4.762s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [28.402s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.13s]
Clearing query masking...  [1.513s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.496s]
Sorting trace points...  [1.242s]
Computing alignments...  [32.01s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.205s]
Computing alignments...  [32.233s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.238s]
Computing alignments...  [32.227s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.187s]
Computing alignments...  [31.594s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.123s]
Computing alignments...  [31.392s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.038s]
Sorting trace points...  [1.082s]
Computing alignments...  [30.889s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.052s]
Sorting trace points...  [0.895s]
Computing alignments...  [30.606s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.126s]
Computing alignments...  [30.217s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.071s]
Sorting trace points...  [0.973s]
Computing alignments...  [30.499s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.075s]
Sorting trace points...  [0.907s]
Computing alignments...  [31.189s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.184s]
Computing alignments...  [30.996s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.084s]
Sorting trace points...  [1.185s]
Computing alignments...  [31.451s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.178s]
Computing alignments...  [31.267s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.209s]
Computing alignments...  [31.336s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.186s]
Computing alignments...  [31.379s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.145s]
Computing alignments...  [30.858s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
 [525.889s]
Deallocating reference...  [0.063s]
Loading reference sequences...  [34.234s]
Masking reference...  [31.174s]
Initializing dictionary...  [0.076s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.274s]
Allocating buffers...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.247s]
Building query seed array...  [1.97s]
Computing hash join...  [5.111s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [76.187s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.021s]
Building query seed array...  [2.308s]
Computing hash join...  [5.05s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [48.549s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.634s]
Building query seed array...  [2.375s]
Computing hash join...  [4.979s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [41.84s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.913s]
Building query seed array...  [1.887s]
Computing hash join...  [4.967s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [38.922s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.885s]
Building query seed array...  [1.751s]
Computing hash join...  [4.795s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [38.432s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.498s]
Building query seed array...  [2.054s]
Computing hash join...  [4.781s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [30.707s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.283s]
Building query seed array...  [2.219s]
Computing hash join...  [4.782s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [33.571s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.839s]
Building query seed array...  [1.791s]
Computing hash join...  [4.84s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [28.167s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.16s]
Clearing query masking...  [1.548s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.53s]
Sorting trace points...  [1.206s]
Computing alignments...  [32.273s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.232s]
Computing alignments...  [32.301s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.247s]
Computing alignments...  [32.343s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.192s]
Computing alignments...  [31.822s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.354s]
Sorting trace points...  [1.219s]
Computing alignments...  [31.518s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.224s]
Computing alignments...  [31.192s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.188s]
Computing alignments...  [30.76s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.108s]
Computing alignments...  [30.265s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.095s]
Sorting trace points...  [1.082s]
Computing alignments...  [30.395s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.203s]
Computing alignments...  [31.105s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.044s]
Computing alignments...  [31.086s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.226s]
Computing alignments...  [31.377s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.176s]
Computing alignments...  [31.165s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.063s]
Sorting trace points...  [0.989s]
Computing alignments...  [31.25s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.187s]
Computing alignments...  [31.295s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.17s]
Computing alignments...  [30.973s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [527.879s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [34.142s]
Masking reference...  [31.322s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.771s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.105s]
Building query seed array...  [1.954s]
Computing hash join...  [5.045s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [77.663s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.814s]
Building query seed array...  [2.283s]
Computing hash join...  [5.033s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [47.624s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.393s]
Building query seed array...  [2.425s]
Computing hash join...  [5.007s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [41.971s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.273s]
Building query seed array...  [1.964s]
Computing hash join...  [4.976s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [37.839s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.65s]
Building query seed array...  [1.79s]
Computing hash join...  [4.854s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [37.985s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.753s]
Building query seed array...  [2.017s]
Computing hash join...  [4.76s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [30.912s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [14.137s]
Building query seed array...  [2.249s]
Computing hash join...  [4.819s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [34.619s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.23s]
Building query seed array...  [1.794s]
Computing hash join...  [4.792s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [29.345s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.448s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.569s]
Sorting trace points...  [1.289s]
Computing alignments...  [31.797s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.209s]
Computing alignments...  [31.94s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.263s]
Computing alignments...  [31.985s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.048s]
Sorting trace points...  [0.96s]
Computing alignments...  [31.393s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.19s]
Computing alignments...  [31.218s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.167s]
Computing alignments...  [30.788s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.154s]
Computing alignments...  [30.492s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.095s]
Computing alignments...  [30.048s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.061s]
Sorting trace points...  [0.966s]
Computing alignments...  [30.453s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.164s]
Computing alignments...  [31.193s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.185s]
Computing alignments...  [30.953s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.146s]
Computing alignments...  [31.372s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.22s]
Computing alignments...  [31.205s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.171s]
Computing alignments...  [31.273s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.187s]
Computing alignments...  [31.268s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.163s]
Computing alignments...  [30.812s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
 [524.465s]
Deallocating reference...  [0.066s]
Loading reference sequences...  [29.504s]
Masking reference...  [32.046s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.716s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.378s]
Building query seed array...  [1.969s]
Computing hash join...  [5.067s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [75.94s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.38s]
Building query seed array...  [2.239s]
Computing hash join...  [5.011s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [48.985s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.333s]
Building query seed array...  [2.364s]
Computing hash join...  [4.898s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [43.95s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.146s]
Building query seed array...  [1.969s]
Computing hash join...  [4.971s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [39.912s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.832s]
Building query seed array...  [1.78s]
Computing hash join...  [4.818s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [37.956s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.274s]
Building query seed array...  [2.037s]
Computing hash join...  [4.907s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [29.998s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.322s]
Building query seed array...  [2.218s]
Computing hash join...  [4.799s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [33.988s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.785s]
Building query seed array...  [1.816s]
Computing hash join...  [4.81s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [29.32s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.131s]
Clearing query masking...  [1.563s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.498s]
Sorting trace points...  [1.279s]
Computing alignments...  [32.882s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.05s]
Sorting trace points...  [0.937s]
Computing alignments...  [32.15s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.063s]
Sorting trace points...  [0.978s]
Computing alignments...  [32.106s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.22s]
Computing alignments...  [31.468s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.163s]
Computing alignments...  [31.208s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.148s]
Computing alignments...  [30.916s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.055s]
Sorting trace points...  [0.961s]
Computing alignments...  [30.5s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.205s]
Computing alignments...  [30.171s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.173s]
Computing alignments...  [30.33s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.196s]
Computing alignments...  [31.144s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.049s]
Computing alignments...  [31.106s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.207s]
Computing alignments...  [31.539s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.092s]
Sorting trace points...  [1.205s]
Computing alignments...  [31.172s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.127s]
Computing alignments...  [31.244s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.159s]
Sorting trace points...  [1.164s]
Computing alignments...  [31.334s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.042s]
Computing alignments...  [30.917s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [526.061s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [23.832s]
Masking reference...  [25.981s]
Initializing dictionary...  [0.064s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [26.519s]
Allocating buffers...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.483s]
Building query seed array...  [1.922s]
Computing hash join...  [4.095s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [59.825s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [10.266s]
Building query seed array...  [2.306s]
Computing hash join...  [4.264s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [39.968s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [11.171s]
Building query seed array...  [2.489s]
Computing hash join...  [4.202s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [33.034s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [7.889s]
Building query seed array...  [1.921s]
Computing hash join...  [4.247s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [30.66s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [8.174s]
Building query seed array...  [1.829s]
Computing hash join...  [3.995s]
Masking low complexity seeds...  [0.197s]
Searching alignments...  [31.023s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [10s]
Building query seed array...  [2.098s]
Computing hash join...  [4.028s]
Masking low complexity seeds...  [0.196s]
Searching alignments...  [25.573s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [10.398s]
Building query seed array...  [2.137s]
Computing hash join...  [4.127s]
Masking low complexity seeds...  [0.193s]
Searching alignments...  [27.378s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [7.98s]
Building query seed array...  [1.738s]
Computing hash join...  [4.019s]
Masking low complexity seeds...  [0.2s]
Searching alignments...  [23.175s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.104s]
Clearing query masking...  [1.535s]
Opening temporary output file...  [0.032s]
Computing alignments... Loading trace points...  [10.844s]
Sorting trace points...  [2.059s]
Computing alignments...  [50.453s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.633s]
Computing alignments...  [50.424s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.106s]
Sorting trace points...  [1.89s]
Computing alignments...  [49.358s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.12s]
Sorting trace points...  [1.607s]
Computing alignments...  [48.528s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.088s]
Sorting trace points...  [1.54s]
Computing alignments...  [49.018s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.098s]
Sorting trace points...  [1.757s]
Computing alignments...  [49.589s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0.142s]
Sorting trace points...  [1.928s]
Computing alignments...  [49.911s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0s]
Sorting trace points...  [1.866s]
Computing alignments...  [49.473s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0s]
 [422.837s]
Deallocating reference...  [0.054s]
Loading reference sequences...  [0.122s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [1858.02s]
 [1858.02s]
Deallocating queries...  [0.059s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [3.506s]
 [4.615s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 17304.5s
Reported 2356276650 pairwise alignments, 2356276650 HSPs.
12482406 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C18_R1.fastp-trim.20230215.fq.gz complete: C18_R1.blastx.meganized.daa

Now MEGANizing C18_R1.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: C18_R1.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 100% (219.8s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.1s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (4,387.7s)
Total reads:       12,482,406
With hits:          12,482,406 
Alignments:      2,341,753,112
Assig. Taxonomy:    11,491,024
Assig. SEED:            98,189
Assig. EGGNOG:          42,418
Assig. GTDB:           345,227
Assig. EC:           2,050,969
Assig. INTERPRO2GO:  1,126,935
MinSupport set to: 6241
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.4s)
Min-supp. changes:       3,540
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (8.3s)
Min-supp. changes:       2,698
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (32.4s)
Binning reads Syncing
100% (0.4s)
Class. Taxonomy:            74
Class. SEED:               464
Class. EGGNOG:           1,647
Class. GTDB:                17
Class. EC:               2,261
Class. INTERPRO2GO:      7,770
Total time:  4,658s
Peak memory: 38.4 of 195.3G
MEGANization of C18_R1.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C18_R2.fastp-trim.20230215.fq.gz...
afe6d73006cb91783c83d76fb4cd9fad  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C18_R2.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C18_R2.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.318s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.73s]
Opening the output file...  [0s]
Loading query sequences...  [70.185s]
Masking queries...  [17.919s]
Algorithm: Double-indexed
Building query histograms...  [17.336s]
Loading reference sequences...  [29.969s]
Masking reference...  [32.16s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.04s]
Allocating buffers...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.095s]
Building query seed array...  [1.994s]
Computing hash join...  [5.279s]
Masking low complexity seeds...  [0.286s]
Searching alignments...  [77.48s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.661s]
Building query seed array...  [2.243s]
Computing hash join...  [5.287s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [49.81s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.515s]
Building query seed array...  [2.435s]
Computing hash join...  [5.185s]
Masking low complexity seeds...  [0.266s]
Searching alignments...  [43.809s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.732s]
Building query seed array...  [1.883s]
Computing hash join...  [5.176s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [40.095s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.213s]
Building query seed array...  [1.762s]
Computing hash join...  [5.008s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [42.108s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.069s]
Building query seed array...  [2.049s]
Computing hash join...  [4.916s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [31.856s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.074s]
Building query seed array...  [2.195s]
Computing hash join...  [5.051s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [35.481s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.719s]
Building query seed array...  [1.777s]
Computing hash join...  [4.943s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [28.927s]
Deallocating memory...  [0s]
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Clearing query masking...  [1.505s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.638s]
Sorting trace points...  [1.243s]
Computing alignments...  [31.988s]
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Computing alignments...  [32.057s]
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Computing alignments...  [32.15s]
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Computing alignments...  [31.293s]
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Computing alignments...  [30.625s]
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Computing alignments...  [30.662s]
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Computing alignments...  [30.034s]
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Computing alignments...  [31.001s]
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Computing alignments...  [31.859s]
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Computing alignments...  [31.984s]
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Computing alignments...  [31.848s]
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Computing alignments...  [31.951s]
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Sorting trace points...  [1.224s]
Computing alignments...  [32.053s]
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Sorting trace points...  [1.195s]
Computing alignments...  [32.283s]
Deallocating buffers...  [0.021s]
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Computing alignments...  [31.822s]
Deallocating buffers...  [0.018s]
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 [532.286s]
Deallocating reference...  [0.067s]
Loading reference sequences...  [29.503s]
Masking reference...  [30.905s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.79s]
Allocating buffers...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.122s]
Building query seed array...  [1.929s]
Computing hash join...  [5.163s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [74.455s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.399s]
Building query seed array...  [2.239s]
Computing hash join...  [5.108s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [48.435s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.565s]
Building query seed array...  [2.383s]
Computing hash join...  [5.065s]
Masking low complexity seeds...  [0.256s]
Searching alignments...  [43.55s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.236s]
Building query seed array...  [2.002s]
Computing hash join...  [5.091s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [38.729s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.103s]
Building query seed array...  [1.742s]
Computing hash join...  [4.923s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [40.635s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.325s]
Building query seed array...  [2.059s]
Computing hash join...  [4.94s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [30.959s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.302s]
Building query seed array...  [2.149s]
Computing hash join...  [4.997s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [33.374s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.911s]
Building query seed array...  [1.719s]
Computing hash join...  [5s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [28.742s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.139s]
Clearing query masking...  [1.534s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.513s]
Sorting trace points...  [1.3s]
Computing alignments...  [31.645s]
Deallocating buffers...  [0.017s]
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Computing alignments...  [31.854s]
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Computing alignments...  [32.196s]
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Computing alignments...  [31.624s]
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Computing alignments...  [31.219s]
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Computing alignments...  [30.47s]
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Computing alignments...  [30.667s]
Deallocating buffers...  [0.026s]
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Computing alignments...  [29.965s]
Deallocating buffers...  [0.016s]
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Sorting trace points...  [1.177s]
Computing alignments...  [30.886s]
Deallocating buffers...  [0.023s]
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Sorting trace points...  [1.218s]
Computing alignments...  [31.716s]
Deallocating buffers...  [0.018s]
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Computing alignments...  [31.797s]
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Computing alignments...  [31.7s]
Deallocating buffers...  [0.019s]
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Computing alignments...  [31.908s]
Deallocating buffers...  [0.022s]
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Computing alignments...  [31.838s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.185s]
Computing alignments...  [32.513s]
Deallocating buffers...  [0.024s]
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Computing alignments...  [31.805s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0s]
 [529.975s]
Deallocating reference...  [0.072s]
Loading reference sequences...  [29.325s]
Masking reference...  [32.157s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [31.739s]
Allocating buffers...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.519s]
Building query seed array...  [1.941s]
Computing hash join...  [5.097s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [76.795s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.286s]
Building query seed array...  [2.264s]
Computing hash join...  [5.09s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [50.507s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [14.118s]
Building query seed array...  [2.414s]
Computing hash join...  [5.093s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [42.789s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.891s]
Building query seed array...  [1.959s]
Computing hash join...  [5.12s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [37.847s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.996s]
Building query seed array...  [1.758s]
Computing hash join...  [4.954s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [40.915s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.521s]
Building query seed array...  [2.009s]
Computing hash join...  [5.018s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [30.768s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.473s]
Building query seed array...  [2.158s]
Computing hash join...  [4.991s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [34.271s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.926s]
Building query seed array...  [1.806s]
Computing hash join...  [4.903s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [29.455s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.556s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.411s]
Sorting trace points...  [1.257s]
Computing alignments...  [31.54s]
Deallocating buffers...  [0.017s]
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Sorting trace points...  [1.179s]
Computing alignments...  [31.825s]
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Computing alignments...  [32.065s]
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Sorting trace points...  [1.191s]
Computing alignments...  [31.427s]
Deallocating buffers...  [0.015s]
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Sorting trace points...  [0.918s]
Computing alignments...  [31.126s]
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Sorting trace points...  [1.177s]
Computing alignments...  [30.546s]
Deallocating buffers...  [0.024s]
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Computing alignments...  [30.647s]
Deallocating buffers...  [0.016s]
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Sorting trace points...  [1.13s]
Computing alignments...  [29.883s]
Deallocating buffers...  [0.017s]
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Sorting trace points...  [0.993s]
Computing alignments...  [30.897s]
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Sorting trace points...  [1.185s]
Computing alignments...  [31.857s]
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Sorting trace points...  [1.24s]
Computing alignments...  [31.815s]
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Sorting trace points...  [1.223s]
Computing alignments...  [31.767s]
Deallocating buffers...  [0.023s]
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Computing alignments...  [31.973s]
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Sorting trace points...  [1.063s]
Computing alignments...  [31.896s]
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Sorting trace points...  [1.257s]
Computing alignments...  [32.345s]
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Computing alignments...  [31.807s]
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 [529.646s]
Deallocating reference...  [0.075s]
Loading reference sequences...  [29.504s]
Masking reference...  [32.096s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.184s]
Allocating buffers...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.394s]
Building query seed array...  [1.93s]
Computing hash join...  [5.088s]
Masking low complexity seeds...  [0.249s]
Searching alignments...  [76.101s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.503s]
Building query seed array...  [2.252s]
Computing hash join...  [5.149s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [49.12s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.418s]
Building query seed array...  [2.349s]
Computing hash join...  [5.021s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [43.274s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.062s]
Building query seed array...  [1.904s]
Computing hash join...  [5.138s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [38.706s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.088s]
Building query seed array...  [1.717s]
Computing hash join...  [5.061s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [41.002s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.355s]
Building query seed array...  [2.107s]
Computing hash join...  [4.991s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [30.906s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.237s]
Building query seed array...  [2.175s]
Computing hash join...  [4.875s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [34.892s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.671s]
Building query seed array...  [1.753s]
Computing hash join...  [4.978s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [28.514s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.476s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.86s]
Sorting trace points...  [1.274s]
Computing alignments...  [31.721s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.061s]
Sorting trace points...  [0.886s]
Computing alignments...  [31.812s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.083s]
Sorting trace points...  [0.978s]
Computing alignments...  [32.251s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.185s]
Computing alignments...  [31.374s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.171s]
Computing alignments...  [31.268s]
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Sorting trace points...  [0.869s]
Computing alignments...  [30.715s]
Deallocating buffers...  [0.023s]
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Sorting trace points...  [0.988s]
Computing alignments...  [30.644s]
Deallocating buffers...  [0.016s]
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Sorting trace points...  [1.093s]
Computing alignments...  [30.08s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.089s]
Sorting trace points...  [1.209s]
Computing alignments...  [30.881s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.232s]
Computing alignments...  [31.955s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.134s]
Computing alignments...  [31.931s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.762s]
Sorting trace points...  [1.227s]
Computing alignments...  [31.891s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.016s]
Computing alignments...  [31.986s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.076s]
Sorting trace points...  [0.926s]
Computing alignments...  [32.195s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.192s]
Computing alignments...  [32.323s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
Sorting trace points...  [1.207s]
Computing alignments...  [31.827s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
 [531.317s]
Deallocating reference...  [0.067s]
Loading reference sequences...  [33.246s]
Masking reference...  [31.114s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.057s]
Allocating buffers...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.192s]
Building query seed array...  [1.989s]
Computing hash join...  [5.11s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [74.03s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.325s]
Building query seed array...  [2.284s]
Computing hash join...  [5.137s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [48.128s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [12.911s]
Building query seed array...  [2.398s]
Computing hash join...  [5.139s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [42.891s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.884s]
Building query seed array...  [1.903s]
Computing hash join...  [5.098s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [37.623s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.209s]
Building query seed array...  [1.77s]
Computing hash join...  [4.909s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [40.188s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.11s]
Building query seed array...  [2.03s]
Computing hash join...  [4.92s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [30.886s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.291s]
Building query seed array...  [2.175s]
Computing hash join...  [4.999s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [33.745s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.875s]
Building query seed array...  [1.817s]
Computing hash join...  [4.941s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [28.758s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.488s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.458s]
Sorting trace points...  [1.271s]
Computing alignments...  [31.573s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.042s]
Sorting trace points...  [1.078s]
Computing alignments...  [31.838s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.259s]
Computing alignments...  [32.129s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.19s]
Computing alignments...  [31.202s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.036s]
Sorting trace points...  [1.223s]
Computing alignments...  [31.209s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.052s]
Sorting trace points...  [0.895s]
Computing alignments...  [30.654s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.147s]
Computing alignments...  [30.68s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.128s]
Computing alignments...  [29.955s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.216s]
Computing alignments...  [30.975s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.222s]
Computing alignments...  [31.816s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.366s]
Sorting trace points...  [1.249s]
Computing alignments...  [31.933s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.06s]
Sorting trace points...  [0.924s]
Computing alignments...  [31.826s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.193s]
Computing alignments...  [31.89s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.161s]
Computing alignments...  [32.046s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.148s]
Computing alignments...  [32.248s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.159s]
Computing alignments...  [31.804s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
 [530.159s]
Deallocating reference...  [0.069s]
Loading reference sequences...  [34.177s]
Masking reference...  [31.181s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.861s]
Allocating buffers...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.504s]
Building query seed array...  [1.945s]
Computing hash join...  [5.155s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [73.797s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.184s]
Building query seed array...  [2.347s]
Computing hash join...  [5.151s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [48.972s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.682s]
Building query seed array...  [2.477s]
Computing hash join...  [5.064s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [41.648s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.949s]
Building query seed array...  [1.935s]
Computing hash join...  [5.017s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [37.346s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.998s]
Building query seed array...  [1.751s]
Computing hash join...  [4.939s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [38.604s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.033s]
Building query seed array...  [2.053s]
Computing hash join...  [4.795s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [31.012s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.324s]
Building query seed array...  [2.2s]
Computing hash join...  [4.963s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [34.811s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.805s]
Building query seed array...  [1.708s]
Computing hash join...  [4.917s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [27.535s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.496s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.468s]
Sorting trace points...  [1.266s]
Computing alignments...  [31.522s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.206s]
Computing alignments...  [31.505s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.231s]
Computing alignments...  [31.627s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.205s]
Computing alignments...  [30.861s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.099s]
Computing alignments...  [30.888s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.166s]
Computing alignments...  [30.166s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.185s]
Computing alignments...  [30.202s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.193s]
Computing alignments...  [29.587s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.179s]
Computing alignments...  [30.627s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.188s]
Computing alignments...  [31.573s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.288s]
Computing alignments...  [31.601s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.229s]
Computing alignments...  [31.515s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.066s]
Sorting trace points...  [0.999s]
Computing alignments...  [31.601s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.236s]
Computing alignments...  [31.729s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.213s]
Computing alignments...  [31.848s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.198s]
Computing alignments...  [31.532s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
 [525.113s]
Deallocating reference...  [0.076s]
Loading reference sequences...  [29.806s]
Masking reference...  [32.224s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.432s]
Allocating buffers...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.47s]
Building query seed array...  [1.979s]
Computing hash join...  [5.148s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [75.878s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.294s]
Building query seed array...  [2.236s]
Computing hash join...  [5.121s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [48.391s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.535s]
Building query seed array...  [2.441s]
Computing hash join...  [5.208s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [42.359s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.921s]
Building query seed array...  [2.009s]
Computing hash join...  [5.076s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [37.691s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.063s]
Building query seed array...  [1.847s]
Computing hash join...  [5.01s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [41.057s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.973s]
Building query seed array...  [2.078s]
Computing hash join...  [4.897s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [30.744s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.562s]
Building query seed array...  [2.218s]
Computing hash join...  [4.909s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [34.471s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.998s]
Building query seed array...  [1.74s]
Computing hash join...  [4.908s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [29.111s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.472s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.49s]
Sorting trace points...  [1.221s]
Computing alignments...  [31.714s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.04s]
Sorting trace points...  [1.21s]
Computing alignments...  [31.947s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.095s]
Sorting trace points...  [1.248s]
Computing alignments...  [32.286s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.159s]
Computing alignments...  [31.464s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.174s]
Computing alignments...  [31.326s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.156s]
Computing alignments...  [30.6s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.001s]
Sorting trace points...  [0.929s]
Computing alignments...  [30.641s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.175s]
Computing alignments...  [29.89s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.157s]
Computing alignments...  [30.984s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.201s]
Computing alignments...  [31.834s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.248s]
Computing alignments...  [31.919s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.171s]
Computing alignments...  [31.881s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.226s]
Computing alignments...  [31.868s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.214s]
Computing alignments...  [31.989s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.034s]
Sorting trace points...  [1.209s]
Computing alignments...  [32.173s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.198s]
Computing alignments...  [31.862s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [530.912s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.671s]
Masking reference...  [30.878s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.006s]
Building reference histograms...  [32.218s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.024s]
Building query seed array...  [1.922s]
Computing hash join...  [5.103s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [75.25s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.309s]
Building query seed array...  [2.302s]
Computing hash join...  [5.114s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [50.351s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.36s]
Building query seed array...  [2.503s]
Computing hash join...  [5.069s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [41.272s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.204s]
Building query seed array...  [1.992s]
Computing hash join...  [5.089s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [38.454s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.532s]
Building query seed array...  [1.8s]
Computing hash join...  [4.909s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [40.276s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.991s]
Building query seed array...  [2.112s]
Computing hash join...  [4.916s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [30.979s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.396s]
Building query seed array...  [2.207s]
Computing hash join...  [4.967s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [35.338s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.066s]
Building query seed array...  [1.786s]
Computing hash join...  [4.896s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [28.603s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.122s]
Clearing query masking...  [1.5s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.465s]
Sorting trace points...  [1.239s]
Computing alignments...  [31.691s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.21s]
Computing alignments...  [31.93s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.219s]
Computing alignments...  [32.136s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.054s]
Sorting trace points...  [0.964s]
Computing alignments...  [31.299s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.195s]
Computing alignments...  [31.217s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.08s]
Sorting trace points...  [0.871s]
Computing alignments...  [30.634s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.173s]
Computing alignments...  [30.585s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.083s]
Computing alignments...  [29.929s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.058s]
Sorting trace points...  [0.944s]
Computing alignments...  [30.961s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.254s]
Computing alignments...  [31.897s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.02s]
Computing alignments...  [31.981s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.218s]
Computing alignments...  [31.827s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.215s]
Computing alignments...  [31.906s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.275s]
Computing alignments...  [32.065s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.278s]
Computing alignments...  [32.265s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.197s]
Computing alignments...  [31.866s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
 [530.198s]
Deallocating reference...  [0.071s]
Loading reference sequences...  [29.788s]
Masking reference...  [31.076s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.005s]
Building reference histograms...  [32.986s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.264s]
Building query seed array...  [1.97s]
Computing hash join...  [5.112s]
Masking low complexity seeds...  [0.249s]
Searching alignments...  [75.954s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.601s]
Building query seed array...  [2.316s]
Computing hash join...  [5.123s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [49.356s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.256s]
Building query seed array...  [2.397s]
Computing hash join...  [5.121s]
Masking low complexity seeds...  [0.259s]
Searching alignments...  [42.403s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.58s]
Building query seed array...  [1.942s]
Computing hash join...  [5.275s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [39.241s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.328s]
Building query seed array...  [1.784s]
Computing hash join...  [4.945s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [41.623s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.245s]
Building query seed array...  [2.114s]
Computing hash join...  [4.858s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [31.856s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.297s]
Building query seed array...  [2.182s]
Computing hash join...  [4.889s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [34.468s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.98s]
Building query seed array...  [1.802s]
Computing hash join...  [4.912s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [28.907s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.489s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.441s]
Sorting trace points...  [1.276s]
Computing alignments...  [31.595s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.04s]
Sorting trace points...  [0.954s]
Computing alignments...  [31.934s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.218s]
Computing alignments...  [32.122s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.163s]
Computing alignments...  [31.332s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.084s]
Sorting trace points...  [0.982s]
Computing alignments...  [31.172s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.216s]
Computing alignments...  [30.712s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.174s]
Computing alignments...  [30.838s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.148s]
Computing alignments...  [30.197s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.063s]
Sorting trace points...  [0.876s]
Computing alignments...  [31.058s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.242s]
Computing alignments...  [31.975s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.101s]
Sorting trace points...  [1.227s]
Computing alignments...  [31.883s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.089s]
Sorting trace points...  [1.265s]
Computing alignments...  [31.78s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.239s]
Computing alignments...  [31.92s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.234s]
Computing alignments...  [32.036s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.034s]
Sorting trace points...  [1.194s]
Computing alignments...  [32.266s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.115s]
Computing alignments...  [31.949s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
 [530.967s]
Deallocating reference...  [0.071s]
Loading reference sequences...  [29.7s]
Masking reference...  [32.126s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.005s]
Building reference histograms...  [32.05s]
Allocating buffers...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.208s]
Building query seed array...  [1.994s]
Computing hash join...  [5.28s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [76.079s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.388s]
Building query seed array...  [2.239s]
Computing hash join...  [5.094s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [50.186s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.118s]
Building query seed array...  [2.356s]
Computing hash join...  [5.165s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [42.015s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.05s]
Building query seed array...  [1.927s]
Computing hash join...  [5.147s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [37.26s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.941s]
Building query seed array...  [1.717s]
Computing hash join...  [4.981s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [40.754s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.721s]
Building query seed array...  [2.049s]
Computing hash join...  [4.878s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [30.912s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.124s]
Building query seed array...  [2.177s]
Computing hash join...  [4.96s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [34.56s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.97s]
Building query seed array...  [1.799s]
Computing hash join...  [4.853s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [29.359s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.135s]
Clearing query masking...  [1.545s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.43s]
Sorting trace points...  [1.251s]
Computing alignments...  [31.64s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.231s]
Computing alignments...  [31.812s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.231s]
Computing alignments...  [32.078s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.035s]
Sorting trace points...  [1.095s]
Computing alignments...  [31.174s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.035s]
Sorting trace points...  [1.241s]
Computing alignments...  [31.115s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.04s]
Sorting trace points...  [0.886s]
Computing alignments...  [30.551s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.115s]
Sorting trace points...  [1.183s]
Computing alignments...  [30.687s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.113s]
Computing alignments...  [29.914s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.167s]
Computing alignments...  [30.891s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.117s]
Computing alignments...  [31.892s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.843s]
Sorting trace points...  [1.251s]
Computing alignments...  [31.87s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.079s]
Sorting trace points...  [0.899s]
Computing alignments...  [31.821s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.002s]
Sorting trace points...  [1.234s]
Computing alignments...  [31.922s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.073s]
Sorting trace points...  [0.971s]
Computing alignments...  [32.078s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.104s]
Sorting trace points...  [1.232s]
Computing alignments...  [32.148s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [1.221s]
Computing alignments...  [31.796s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
 [530.137s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [29.745s]
Masking reference...  [30.838s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.005s]
Building reference histograms...  [32.858s]
Allocating buffers...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.172s]
Building query seed array...  [1.944s]
Computing hash join...  [5.188s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [76.144s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.497s]
Building query seed array...  [2.321s]
Computing hash join...  [5.118s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [50.263s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.514s]
Building query seed array...  [2.431s]
Computing hash join...  [5s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [43.601s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.041s]
Building query seed array...  [1.909s]
Computing hash join...  [5.093s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [37.713s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.266s]
Building query seed array...  [1.79s]
Computing hash join...  [5.05s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [39.78s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.439s]
Building query seed array...  [2.112s]
Computing hash join...  [4.886s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [31.486s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.244s]
Building query seed array...  [2.263s]
Computing hash join...  [4.884s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [34.758s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.633s]
Building query seed array...  [1.799s]
Computing hash join...  [4.888s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [28.078s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.122s]
Clearing query masking...  [1.46s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.901s]
Sorting trace points...  [1.206s]
Computing alignments...  [31.789s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.203s]
Computing alignments...  [32.086s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.067s]
Sorting trace points...  [0.965s]
Computing alignments...  [32.407s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.104s]
Computing alignments...  [31.786s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.084s]
Computing alignments...  [31.404s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.019s]
Computing alignments...  [30.633s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.223s]
Computing alignments...  [31.015s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.123s]
Computing alignments...  [30.103s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.056s]
Computing alignments...  [31.039s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.154s]
Computing alignments...  [31.822s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.071s]
Sorting trace points...  [0.965s]
Computing alignments...  [31.938s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.11s]
Sorting trace points...  [1.111s]
Computing alignments...  [31.811s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.238s]
Computing alignments...  [31.979s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.203s]
Computing alignments...  [32.212s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.277s]
Computing alignments...  [32.205s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [0.958s]
Computing alignments...  [31.861s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [531.988s]
Deallocating reference...  [0.07s]
Loading reference sequences...  [30.087s]
Masking reference...  [30.849s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.006s]
Building reference histograms...  [32.653s]
Allocating buffers...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.599s]
Building query seed array...  [1.953s]
Computing hash join...  [5.146s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [77.1s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.749s]
Building query seed array...  [2.258s]
Computing hash join...  [5.114s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [48.404s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.399s]
Building query seed array...  [2.442s]
Computing hash join...  [5.093s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [42.967s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.985s]
Building query seed array...  [1.951s]
Computing hash join...  [5.163s]
Masking low complexity seeds...  [0.256s]
Searching alignments...  [38.778s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.013s]
Building query seed array...  [1.753s]
Computing hash join...  [4.941s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [42.451s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.312s]
Building query seed array...  [2.065s]
Computing hash join...  [4.883s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [31.343s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [14.04s]
Building query seed array...  [2.211s]
Computing hash join...  [4.925s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [34.479s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.779s]
Building query seed array...  [1.768s]
Computing hash join...  [5.002s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [29.391s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.5s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.478s]
Sorting trace points...  [1.2s]
Computing alignments...  [31.396s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.258s]
Computing alignments...  [31.527s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.092s]
Sorting trace points...  [1.101s]
Computing alignments...  [31.809s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.042s]
Sorting trace points...  [0.987s]
Computing alignments...  [31.095s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.241s]
Computing alignments...  [31.06s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.174s]
Computing alignments...  [30.528s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
Sorting trace points...  [0.948s]
Computing alignments...  [30.589s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.156s]
Computing alignments...  [29.972s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.162s]
Computing alignments...  [30.775s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.113s]
Sorting trace points...  [1.119s]
Computing alignments...  [31.781s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.229s]
Computing alignments...  [31.816s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.226s]
Computing alignments...  [31.761s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.216s]
Computing alignments...  [31.844s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.2s]
Sorting trace points...  [0.943s]
Computing alignments...  [31.938s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.203s]
Computing alignments...  [32.107s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [0.919s]
Computing alignments...  [31.753s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [527.676s]
Deallocating reference...  [0.075s]
Loading reference sequences...  [29.645s]
Masking reference...  [30.847s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.006s]
Building reference histograms...  [32.828s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.452s]
Building query seed array...  [1.969s]
Computing hash join...  [5.153s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [77.501s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.563s]
Building query seed array...  [2.269s]
Computing hash join...  [5.157s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [47.293s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.27s]
Building query seed array...  [2.474s]
Computing hash join...  [5.214s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [41.641s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.803s]
Building query seed array...  [1.984s]
Computing hash join...  [5.099s]
Masking low complexity seeds...  [0.249s]
Searching alignments...  [37.813s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.956s]
Building query seed array...  [1.78s]
Computing hash join...  [4.923s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [40.653s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.293s]
Building query seed array...  [2.033s]
Computing hash join...  [4.904s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [30.887s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.29s]
Building query seed array...  [2.141s]
Computing hash join...  [5.011s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [34.124s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.795s]
Building query seed array...  [1.808s]
Computing hash join...  [4.941s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [28.87s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.122s]
Clearing query masking...  [1.453s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.495s]
Sorting trace points...  [1.19s]
Computing alignments...  [31.814s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.015s]
Computing alignments...  [31.868s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.27s]
Computing alignments...  [32.106s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.036s]
Sorting trace points...  [1.184s]
Computing alignments...  [31.472s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.109s]
Sorting trace points...  [1.206s]
Computing alignments...  [31.292s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.038s]
Computing alignments...  [30.581s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.202s]
Computing alignments...  [30.684s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.136s]
Sorting trace points...  [1.161s]
Computing alignments...  [29.912s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.081s]
Sorting trace points...  [0.918s]
Computing alignments...  [30.97s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.252s]
Computing alignments...  [31.815s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.2s]
Computing alignments...  [31.856s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.089s]
Sorting trace points...  [1.179s]
Computing alignments...  [31.75s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.957s]
Sorting trace points...  [1.267s]
Computing alignments...  [31.82s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.058s]
Sorting trace points...  [0.946s]
Computing alignments...  [31.876s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.031s]
Sorting trace points...  [1.249s]
Computing alignments...  [32.348s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.241s]
Computing alignments...  [31.83s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [531.312s]
Deallocating reference...  [0.074s]
Loading reference sequences...  [25.8s]
Masking reference...  [26.078s]
Initializing dictionary...  [0.062s]
Initializing temporary storage...  [0.005s]
Building reference histograms...  [26.094s]
Allocating buffers...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.393s]
Building query seed array...  [1.955s]
Computing hash join...  [4.305s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [61.461s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [10.041s]
Building query seed array...  [2.384s]
Computing hash join...  [4.258s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [38.871s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [10.783s]
Building query seed array...  [2.387s]
Computing hash join...  [4.226s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [34.175s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [8.283s]
Building query seed array...  [1.922s]
Computing hash join...  [4.213s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [32.124s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [7.95s]
Building query seed array...  [1.78s]
Computing hash join...  [4.078s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [33.243s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [9.737s]
Building query seed array...  [2.159s]
Computing hash join...  [4.034s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [25.267s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [11.229s]
Building query seed array...  [2.207s]
Computing hash join...  [4.145s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [28.137s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [8.006s]
Building query seed array...  [1.774s]
Computing hash join...  [4.085s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [23.385s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.115s]
Clearing query masking...  [1.542s]
Opening temporary output file...  [0.019s]
Computing alignments... Loading trace points...  [11.015s]
Sorting trace points...  [2.113s]
Computing alignments...  [50.585s]
Deallocating buffers...  [0.037s]
Loading trace points...  [0.135s]
Sorting trace points...  [1.8s]
Computing alignments...  [50.365s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.144s]
Sorting trace points...  [1.646s]
Computing alignments...  [49.201s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.168s]
Sorting trace points...  [1.848s]
Computing alignments...  [48.208s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.073s]
Sorting trace points...  [2.003s]
Computing alignments...  [49.921s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.091s]
Sorting trace points...  [2.048s]
Computing alignments...  [50.724s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.121s]
Sorting trace points...  [1.733s]
Computing alignments...  [50.832s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
Sorting trace points...  [1.952s]
Computing alignments...  [50.533s]
Deallocating buffers...  [0.035s]
Loading trace points...  [0s]
 [427.666s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [0.071s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [1846.79s]
 [1846.79s]
Deallocating queries...  [0.053s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [3.552s]
 [4.651s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 17398.4s
Reported 2302232119 pairwise alignments, 2302232119 HSPs.
12809835 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C18_R2.fastp-trim.20230215.fq.gz complete: C18_R2.blastx.meganized.daa

Now MEGANizing C18_R2.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: C18_R2.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 100% (256.2s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.2s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (4,389.6s)
Total reads:       12,809,835
With hits:          12,809,835 
Alignments:      2,292,127,840
Assig. Taxonomy:    11,773,622
Assig. SEED:            95,426
Assig. EGGNOG:          41,960
Assig. GTDB:           337,071
Assig. EC:           2,093,302
Assig. INTERPRO2GO:  1,126,630
MinSupport set to: 6404
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.4s)
Min-supp. changes:       3,644
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (10.1s)
Min-supp. changes:       2,782
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (28.3s)
Binning reads Syncing
100% (0.4s)
Class. Taxonomy:            73
Class. SEED:               467
Class. EGGNOG:           1,655
Class. GTDB:                15
Class. EC:               2,269
Class. INTERPRO2GO:      7,849
Total time:  4,694s
Peak memory: 30.8 of 195.3G
MEGANization of C18_R2.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C19_R1.fastp-trim.20230215.fq.gz...
00b83460c674d3d9fd368c439acb73a8  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C19_R1.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C19_R1.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.322s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.731s]
Opening the output file...  [0s]
Loading query sequences...  [76.076s]
Masking queries...  [19.454s]
Algorithm: Double-indexed
Building query histograms...  [23.044s]
Loading reference sequences...  [31.599s]
Masking reference...  [31.961s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.358s]
Allocating buffers...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.49s]
Building query seed array...  [2.095s]
Computing hash join...  [5.305s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [83.13s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [13.069s]
Building query seed array...  [2.431s]
Computing hash join...  [5.112s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [58.857s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.405s]
Building query seed array...  [2.605s]
Computing hash join...  [5.085s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [46.578s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.076s]
Building query seed array...  [2.171s]
Computing hash join...  [5.067s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [41.282s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.664s]
Building query seed array...  [1.942s]
Computing hash join...  [4.969s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [42.68s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.168s]
Building query seed array...  [2.17s]
Computing hash join...  [4.944s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [33.76s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.243s]
Building query seed array...  [2.351s]
Computing hash join...  [4.891s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [36.689s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.101s]
Building query seed array...  [1.938s]
Computing hash join...  [4.893s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [31.265s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.129s]
Clearing query masking...  [1.674s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.626s]
Sorting trace points...  [1.345s]
Computing alignments...  [32.756s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.063s]
Computing alignments...  [32.968s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.244s]
Computing alignments...  [32.585s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.049s]
Computing alignments...  [33.647s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.264s]
Computing alignments...  [33.816s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.894s]
Sorting trace points...  [1.339s]
Computing alignments...  [34.531s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.326s]
Computing alignments...  [33.797s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.001s]
Sorting trace points...  [0.993s]
Computing alignments...  [33.537s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.053s]
Sorting trace points...  [0.95s]
Computing alignments...  [33.658s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.038s]
Sorting trace points...  [1.268s]
Computing alignments...  [33.314s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.245s]
Computing alignments...  [33.604s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.246s]
Computing alignments...  [33.205s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.247s]
Computing alignments...  [33.617s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.212s]
Computing alignments...  [33.74s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.287s]
Computing alignments...  [33.591s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
Sorting trace points...  [0.982s]
Computing alignments...  [33.351s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [563.293s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [29.452s]
Masking reference...  [30.923s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.737s]
Allocating buffers...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.156s]
Building query seed array...  [2.141s]
Computing hash join...  [5.125s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [82.046s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.942s]
Building query seed array...  [2.444s]
Computing hash join...  [5.087s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [57.264s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.488s]
Building query seed array...  [2.644s]
Computing hash join...  [5.184s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [45.05s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.338s]
Building query seed array...  [2.171s]
Computing hash join...  [5.034s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [39.78s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.143s]
Building query seed array...  [1.937s]
Computing hash join...  [4.882s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [40.911s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.203s]
Building query seed array...  [2.167s]
Computing hash join...  [4.784s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [33.449s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.921s]
Building query seed array...  [2.398s]
Computing hash join...  [4.926s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [36.175s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.846s]
Building query seed array...  [1.931s]
Computing hash join...  [4.816s]
Masking low complexity seeds...  [0.2s]
Searching alignments...  [30.598s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.122s]
Clearing query masking...  [1.616s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.618s]
Sorting trace points...  [1.301s]
Computing alignments...  [32.634s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.251s]
Computing alignments...  [32.671s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.078s]
Sorting trace points...  [0.905s]
Computing alignments...  [32.606s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.055s]
Sorting trace points...  [0.98s]
Computing alignments...  [33.474s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.026s]
Computing alignments...  [33.789s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.098s]
Computing alignments...  [34.319s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.319s]
Computing alignments...  [33.523s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.301s]
Computing alignments...  [33.484s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.288s]
Computing alignments...  [33.436s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.088s]
Sorting trace points...  [1.235s]
Computing alignments...  [33.279s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.251s]
Computing alignments...  [33.552s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.143s]
Computing alignments...  [33.175s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.293s]
Computing alignments...  [33.352s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.276s]
Computing alignments...  [33.689s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.297s]
Computing alignments...  [33.532s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.251s]
Computing alignments...  [33.169s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [560.714s]
Deallocating reference...  [0.063s]
Loading reference sequences...  [29.712s]
Masking reference...  [30.941s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.979s]
Allocating buffers...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.204s]
Building query seed array...  [2.067s]
Computing hash join...  [5.094s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [86.148s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [11.913s]
Building query seed array...  [2.469s]
Computing hash join...  [5.164s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [60.278s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.793s]
Building query seed array...  [2.528s]
Computing hash join...  [5.08s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [46.755s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.204s]
Building query seed array...  [2.169s]
Computing hash join...  [5.076s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [39.852s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.732s]
Building query seed array...  [1.947s]
Computing hash join...  [4.897s]
Masking low complexity seeds...  [0.198s]
Searching alignments...  [41.307s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.594s]
Building query seed array...  [2.207s]
Computing hash join...  [4.805s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [33.621s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.653s]
Building query seed array...  [2.368s]
Computing hash join...  [4.857s]
Masking low complexity seeds...  [0.198s]
Searching alignments...  [36.605s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.278s]
Building query seed array...  [1.954s]
Computing hash join...  [4.886s]
Masking low complexity seeds...  [0.198s]
Searching alignments...  [32.574s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.134s]
Clearing query masking...  [1.677s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.711s]
Sorting trace points...  [1.323s]
Computing alignments...  [32.527s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.27s]
Computing alignments...  [32.811s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.222s]
Computing alignments...  [32.523s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.099s]
Sorting trace points...  [0.965s]
Computing alignments...  [33.519s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.038s]
Sorting trace points...  [1.128s]
Computing alignments...  [33.562s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.308s]
Computing alignments...  [34.14s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.095s]
Sorting trace points...  [1.268s]
Computing alignments...  [33.534s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.063s]
Sorting trace points...  [0.966s]
Computing alignments...  [33.383s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.268s]
Computing alignments...  [33.384s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.269s]
Computing alignments...  [33.106s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.107s]
Computing alignments...  [33.311s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.286s]
Computing alignments...  [33.008s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.287s]
Computing alignments...  [33.28s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.279s]
Computing alignments...  [33.545s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.288s]
Computing alignments...  [33.553s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
Sorting trace points...  [1.285s]
Computing alignments...  [33.06s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
 [559.563s]
Deallocating reference...  [0.069s]
Loading reference sequences...  [29.563s]
Masking reference...  [31.054s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.887s]
Allocating buffers...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.606s]
Building query seed array...  [2.098s]
Computing hash join...  [5.058s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [82.524s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.422s]
Building query seed array...  [2.41s]
Computing hash join...  [5.171s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [56.96s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.1s]
Building query seed array...  [2.637s]
Computing hash join...  [5.109s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [47.053s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.331s]
Building query seed array...  [2.115s]
Computing hash join...  [5.064s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [40.994s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.148s]
Building query seed array...  [1.926s]
Computing hash join...  [4.95s]
Masking low complexity seeds...  [0.2s]
Searching alignments...  [41.739s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.657s]
Building query seed array...  [2.202s]
Computing hash join...  [5.043s]
Masking low complexity seeds...  [0.2s]
Searching alignments...  [34.204s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.152s]
Building query seed array...  [2.38s]
Computing hash join...  [4.818s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [36.318s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.304s]
Building query seed array...  [1.921s]
Computing hash join...  [4.817s]
Masking low complexity seeds...  [0.2s]
Searching alignments...  [31.019s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.583s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.792s]
Sorting trace points...  [1.306s]
Computing alignments...  [32.429s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.29s]
Computing alignments...  [32.766s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.091s]
Sorting trace points...  [1.246s]
Computing alignments...  [32.348s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.102s]
Computing alignments...  [33.556s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.252s]
Computing alignments...  [33.694s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.367s]
Computing alignments...  [34.213s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.083s]
Computing alignments...  [33.475s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.255s]
Computing alignments...  [33.275s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.081s]
Sorting trace points...  [0.941s]
Computing alignments...  [33.26s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.268s]
Computing alignments...  [33.115s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.116s]
Sorting trace points...  [1.289s]
Computing alignments...  [33.309s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.263s]
Computing alignments...  [32.961s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.928s]
Sorting trace points...  [1.3s]
Computing alignments...  [33.287s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.285s]
Computing alignments...  [33.567s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.162s]
Computing alignments...  [33.373s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.084s]
Computing alignments...  [33.119s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [560.253s]
Deallocating reference...  [0.064s]
Loading reference sequences...  [29.523s]
Masking reference...  [32.043s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.419s]
Allocating buffers...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.406s]
Building query seed array...  [2.118s]
Computing hash join...  [5.153s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [82.777s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [11.924s]
Building query seed array...  [2.484s]
Computing hash join...  [5.135s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [56.401s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.492s]
Building query seed array...  [2.646s]
Computing hash join...  [5.044s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [45.53s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.14s]
Building query seed array...  [2.114s]
Computing hash join...  [5.119s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [40.012s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.114s]
Building query seed array...  [1.867s]
Computing hash join...  [4.838s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [41.338s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.367s]
Building query seed array...  [2.257s]
Computing hash join...  [4.91s]
Masking low complexity seeds...  [0.196s]
Searching alignments...  [33.091s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.504s]
Building query seed array...  [2.349s]
Computing hash join...  [4.823s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [36.729s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.857s]
Building query seed array...  [1.986s]
Computing hash join...  [4.877s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [30.863s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.141s]
Clearing query masking...  [1.66s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.518s]
Sorting trace points...  [1.328s]
Computing alignments...  [32.406s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.085s]
Sorting trace points...  [1.292s]
Computing alignments...  [32.616s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.125s]
Computing alignments...  [32.272s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.088s]
Sorting trace points...  [0.94s]
Computing alignments...  [33.418s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.303s]
Computing alignments...  [33.68s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.039s]
Sorting trace points...  [1.379s]
Computing alignments...  [34.108s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.015s]
Computing alignments...  [33.477s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.302s]
Computing alignments...  [33.354s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.114s]
Sorting trace points...  [1.272s]
Computing alignments...  [33.314s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.213s]
Computing alignments...  [33.082s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.107s]
Sorting trace points...  [1.283s]
Computing alignments...  [33.435s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.105s]
Sorting trace points...  [1.221s]
Computing alignments...  [33.017s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.122s]
Computing alignments...  [33.318s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.258s]
Computing alignments...  [33.53s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.303s]
Computing alignments...  [33.324s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
Sorting trace points...  [1.279s]
Computing alignments...  [33s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [558.933s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [245.347s]
Masking reference...  [30.848s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.989s]
Allocating buffers...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.576s]
Building query seed array...  [2.122s]
Computing hash join...  [5.038s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [81.11s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.476s]
Building query seed array...  [2.47s]
Computing hash join...  [5.017s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [55.999s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.439s]
Building query seed array...  [2.63s]
Computing hash join...  [4.967s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [44.301s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.102s]
Building query seed array...  [2.089s]
Computing hash join...  [5.046s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [39.021s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.388s]
Building query seed array...  [1.916s]
Computing hash join...  [4.872s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [39.661s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.159s]
Building query seed array...  [2.25s]
Computing hash join...  [4.848s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [32.995s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.151s]
Building query seed array...  [2.387s]
Computing hash join...  [4.816s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [35.126s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.031s]
Building query seed array...  [1.954s]
Computing hash join...  [4.865s]
Masking low complexity seeds...  [0.199s]
Searching alignments...  [30.244s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.143s]
Clearing query masking...  [1.665s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.7s]
Sorting trace points...  [1.245s]
Computing alignments...  [32.166s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.243s]
Computing alignments...  [32.39s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.258s]
Computing alignments...  [31.988s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.25s]
Computing alignments...  [32.92s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.012s]
Computing alignments...  [33.221s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.087s]
Sorting trace points...  [1.294s]
Computing alignments...  [33.778s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.278s]
Computing alignments...  [32.946s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.103s]
Sorting trace points...  [1.277s]
Computing alignments...  [32.755s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.263s]
Computing alignments...  [32.879s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.243s]
Computing alignments...  [32.84s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.252s]
Computing alignments...  [33.071s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.266s]
Computing alignments...  [32.746s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.28s]
Computing alignments...  [33.203s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.282s]
Computing alignments...  [33.29s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.289s]
Computing alignments...  [33.138s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [1.082s]
Computing alignments...  [32.789s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [553.885s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [36.022s]
Masking reference...  [30.841s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.896s]
Allocating buffers...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.112s]
Building query seed array...  [2.166s]
Computing hash join...  [5.046s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [83.939s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.657s]
Building query seed array...  [2.436s]
Computing hash join...  [5.038s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [57.852s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [12.898s]
Building query seed array...  [2.581s]
Computing hash join...  [5.049s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [46.168s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.072s]
Building query seed array...  [2.086s]
Computing hash join...  [4.99s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [41.309s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.422s]
Building query seed array...  [1.932s]
Computing hash join...  [4.892s]
Masking low complexity seeds...  [0.198s]
Searching alignments...  [41.293s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.318s]
Building query seed array...  [2.185s]
Computing hash join...  [4.892s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [32.506s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.727s]
Building query seed array...  [2.467s]
Computing hash join...  [4.809s]
Masking low complexity seeds...  [0.199s]
Searching alignments...  [38.357s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.946s]
Building query seed array...  [1.957s]
Computing hash join...  [4.873s]
Masking low complexity seeds...  [0.191s]
Searching alignments...  [31.359s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.144s]
Clearing query masking...  [1.621s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.587s]
Sorting trace points...  [1.345s]
Computing alignments...  [32.403s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.056s]
Sorting trace points...  [0.967s]
Computing alignments...  [33.072s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.038s]
Sorting trace points...  [1.214s]
Computing alignments...  [32.426s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.182s]
Computing alignments...  [33.522s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.28s]
Computing alignments...  [33.647s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.07s]
Computing alignments...  [34.338s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.295s]
Computing alignments...  [33.624s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.112s]
Computing alignments...  [33.399s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.293s]
Computing alignments...  [33.312s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.187s]
Computing alignments...  [33.146s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.295s]
Computing alignments...  [33.429s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.053s]
Sorting trace points...  [0.938s]
Computing alignments...  [32.975s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.153s]
Computing alignments...  [33.351s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.332s]
Computing alignments...  [33.569s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.271s]
Computing alignments...  [33.44s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.314s]
Computing alignments...  [33.178s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [559.838s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.648s]
Masking reference...  [30.865s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.385s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.136s]
Building query seed array...  [2.074s]
Computing hash join...  [5.068s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [83.26s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.457s]
Building query seed array...  [2.48s]
Computing hash join...  [5.04s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [58.234s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.616s]
Building query seed array...  [2.669s]
Computing hash join...  [5.045s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [47.038s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.149s]
Building query seed array...  [2.108s]
Computing hash join...  [5.059s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [43.441s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.837s]
Building query seed array...  [1.88s]
Computing hash join...  [4.786s]
Masking low complexity seeds...  [0.193s]
Searching alignments...  [40.124s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.542s]
Building query seed array...  [2.252s]
Computing hash join...  [4.823s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [34.387s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.507s]
Building query seed array...  [2.458s]
Computing hash join...  [4.844s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [35.935s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.061s]
Building query seed array...  [1.904s]
Computing hash join...  [4.82s]
Masking low complexity seeds...  [0.196s]
Searching alignments...  [31.017s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.13s]
Clearing query masking...  [1.726s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.674s]
Sorting trace points...  [1.319s]
Computing alignments...  [32.348s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.227s]
Computing alignments...  [32.779s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.271s]
Computing alignments...  [32.293s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.242s]
Computing alignments...  [33.329s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.089s]
Computing alignments...  [33.622s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.339s]
Computing alignments...  [34.086s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.269s]
Computing alignments...  [33.46s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.292s]
Computing alignments...  [33.192s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.219s]
Computing alignments...  [33.208s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.074s]
Computing alignments...  [33.081s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.196s]
Computing alignments...  [33.284s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.087s]
Sorting trace points...  [1.315s]
Computing alignments...  [32.911s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.17s]
Computing alignments...  [33.261s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.037s]
Sorting trace points...  [1.288s]
Computing alignments...  [33.492s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.045s]
Sorting trace points...  [0.994s]
Computing alignments...  [33.337s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.264s]
Computing alignments...  [33.056s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
 [558.101s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [34.703s]
Masking reference...  [30.996s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.688s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.34s]
Building query seed array...  [2.155s]
Computing hash join...  [5.065s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [83.758s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.432s]
Building query seed array...  [2.47s]
Computing hash join...  [5.018s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [57.921s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.597s]
Building query seed array...  [2.659s]
Computing hash join...  [5.072s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [45.27s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.108s]
Building query seed array...  [2.084s]
Computing hash join...  [4.967s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [39.315s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.984s]
Building query seed array...  [1.885s]
Computing hash join...  [4.942s]
Masking low complexity seeds...  [0.199s]
Searching alignments...  [41.216s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.807s]
Building query seed array...  [2.212s]
Computing hash join...  [4.841s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [33.243s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.364s]
Building query seed array...  [2.314s]
Computing hash join...  [4.876s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [35.591s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.033s]
Building query seed array...  [1.909s]
Computing hash join...  [4.859s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [31.339s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.646s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.652s]
Sorting trace points...  [1.336s]
Computing alignments...  [32.63s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.282s]
Computing alignments...  [32.669s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.047s]
Computing alignments...  [32.402s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.274s]
Computing alignments...  [33.501s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.013s]
Computing alignments...  [33.584s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.323s]
Computing alignments...  [34.209s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.023s]
Computing alignments...  [33.454s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.078s]
Sorting trace points...  [0.948s]
Computing alignments...  [33.268s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.188s]
Computing alignments...  [33.291s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.301s]
Computing alignments...  [33.109s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.3s]
Computing alignments...  [33.385s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.02s]
Computing alignments...  [32.975s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.283s]
Computing alignments...  [33.294s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.267s]
Computing alignments...  [33.535s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.134s]
Computing alignments...  [33.399s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
Sorting trace points...  [1.273s]
Computing alignments...  [33.1s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
 [558.801s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [34.515s]
Masking reference...  [30.852s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.398s]
Allocating buffers...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10s]
Building query seed array...  [2.122s]
Computing hash join...  [5.033s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [85.348s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.483s]
Building query seed array...  [2.524s]
Computing hash join...  [5.082s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [57.175s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.663s]
Building query seed array...  [2.604s]
Computing hash join...  [5.117s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [46.697s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.05s]
Building query seed array...  [2.152s]
Computing hash join...  [5.039s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [41.23s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.806s]
Building query seed array...  [1.865s]
Computing hash join...  [4.793s]
Masking low complexity seeds...  [0.195s]
Searching alignments...  [41.268s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.427s]
Building query seed array...  [2.288s]
Computing hash join...  [4.868s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [33.34s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.919s]
Building query seed array...  [2.423s]
Computing hash join...  [4.816s]
Masking low complexity seeds...  [0.195s]
Searching alignments...  [37.425s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.363s]
Building query seed array...  [1.97s]
Computing hash join...  [4.833s]
Masking low complexity seeds...  [0.198s]
Searching alignments...  [31.983s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.131s]
Clearing query masking...  [1.631s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.595s]
Sorting trace points...  [1.305s]
Computing alignments...  [32.292s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.023s]
Computing alignments...  [32.675s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.073s]
Sorting trace points...  [0.997s]
Computing alignments...  [32.285s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.296s]
Sorting trace points...  [1.133s]
Computing alignments...  [33.386s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.283s]
Computing alignments...  [33.566s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.039s]
Sorting trace points...  [1.322s]
Computing alignments...  [34.041s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.084s]
Sorting trace points...  [1.261s]
Computing alignments...  [33.365s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.325s]
Computing alignments...  [33.142s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.111s]
Computing alignments...  [33.26s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.09s]
Sorting trace points...  [1.316s]
Computing alignments...  [33.034s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.215s]
Computing alignments...  [33.199s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.089s]
Sorting trace points...  [1.293s]
Computing alignments...  [32.86s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.258s]
Computing alignments...  [33.289s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.003s]
Computing alignments...  [33.523s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.06s]
Sorting trace points...  [0.966s]
Computing alignments...  [33.379s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [1.283s]
Computing alignments...  [33.036s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
 [557.527s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [30.539s]
Masking reference...  [32.151s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.169s]
Allocating buffers...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [9.94s]
Building query seed array...  [2.117s]
Computing hash join...  [5.071s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [81.977s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.304s]
Building query seed array...  [2.424s]
Computing hash join...  [4.988s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [57.212s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.395s]
Building query seed array...  [2.593s]
Computing hash join...  [5.079s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [44.259s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.875s]
Building query seed array...  [2.08s]
Computing hash join...  [5.076s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [40.385s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.115s]
Building query seed array...  [1.906s]
Computing hash join...  [4.955s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [40.726s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.181s]
Building query seed array...  [2.218s]
Computing hash join...  [4.875s]
Masking low complexity seeds...  [0.199s]
Searching alignments...  [32.722s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.379s]
Building query seed array...  [2.33s]
Computing hash join...  [4.86s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [35.968s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.637s]
Building query seed array...  [1.943s]
Computing hash join...  [4.818s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [30.425s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.665s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.712s]
Sorting trace points...  [1.283s]
Computing alignments...  [32.619s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.188s]
Computing alignments...  [32.64s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.272s]
Computing alignments...  [32.318s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.038s]
Sorting trace points...  [1.282s]
Computing alignments...  [33.503s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.29s]
Computing alignments...  [33.598s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.299s]
Computing alignments...  [34.268s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.053s]
Computing alignments...  [33.486s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.075s]
Computing alignments...  [33.249s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.27s]
Computing alignments...  [33.43s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.076s]
Sorting trace points...  [0.954s]
Computing alignments...  [33.098s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.034s]
Sorting trace points...  [1.316s]
Computing alignments...  [33.377s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.277s]
Computing alignments...  [32.895s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.168s]
Computing alignments...  [33.256s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.256s]
Computing alignments...  [33.547s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.296s]
Computing alignments...  [33.35s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
Sorting trace points...  [1.317s]
Computing alignments...  [33.007s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
 [559.117s]
Deallocating reference...  [0.065s]
Loading reference sequences...  [29.606s]
Masking reference...  [32.074s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.147s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.744s]
Building query seed array...  [2.139s]
Computing hash join...  [5.034s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [84.297s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.436s]
Building query seed array...  [2.442s]
Computing hash join...  [5.075s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [60.084s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.169s]
Building query seed array...  [2.648s]
Computing hash join...  [5.072s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [46.995s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.101s]
Building query seed array...  [2.101s]
Computing hash join...  [5.048s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [40.453s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.98s]
Building query seed array...  [1.985s]
Computing hash join...  [4.858s]
Masking low complexity seeds...  [0.2s]
Searching alignments...  [41.694s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.413s]
Building query seed array...  [2.213s]
Computing hash join...  [4.863s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [32.467s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.334s]
Building query seed array...  [2.362s]
Computing hash join...  [4.949s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [36.598s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.162s]
Building query seed array...  [1.915s]
Computing hash join...  [4.778s]
Masking low complexity seeds...  [0.194s]
Searching alignments...  [31.407s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.142s]
Clearing query masking...  [1.681s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.634s]
Sorting trace points...  [1.29s]
Computing alignments...  [32.401s]
Deallocating buffers...  [0.023s]
Loading trace points...  [1.155s]
Sorting trace points...  [1.029s]
Computing alignments...  [32.589s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.225s]
Computing alignments...  [32.323s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.301s]
Computing alignments...  [33.337s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.267s]
Computing alignments...  [33.382s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.332s]
Computing alignments...  [34.033s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.095s]
Computing alignments...  [33.351s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.156s]
Computing alignments...  [33.081s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.236s]
Computing alignments...  [33.155s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.002s]
Sorting trace points...  [1.275s]
Computing alignments...  [33.184s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.093s]
Computing alignments...  [33.394s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.266s]
Computing alignments...  [33.115s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.159s]
Computing alignments...  [33.468s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.277s]
Computing alignments...  [33.666s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.033s]
Sorting trace points...  [0.989s]
Computing alignments...  [33.344s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.281s]
Computing alignments...  [32.982s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
 [558.915s]
Deallocating reference...  [0.067s]
Loading reference sequences...  [29.452s]
Masking reference...  [30.858s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.804s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.327s]
Building query seed array...  [2.14s]
Computing hash join...  [5.064s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [84.97s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.511s]
Building query seed array...  [2.463s]
Computing hash join...  [5.13s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [58.13s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.511s]
Building query seed array...  [2.596s]
Computing hash join...  [5.072s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [46.472s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.78s]
Building query seed array...  [2.111s]
Computing hash join...  [5.007s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [40.891s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.793s]
Building query seed array...  [1.907s]
Computing hash join...  [4.897s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [41.357s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.553s]
Building query seed array...  [2.211s]
Computing hash join...  [4.76s]
Masking low complexity seeds...  [0.196s]
Searching alignments...  [32.922s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.398s]
Building query seed array...  [2.404s]
Computing hash join...  [4.9s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [36.292s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.84s]
Building query seed array...  [1.955s]
Computing hash join...  [4.835s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [31.166s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.136s]
Clearing query masking...  [1.629s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.534s]
Sorting trace points...  [1.29s]
Computing alignments...  [32.452s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.102s]
Sorting trace points...  [1.266s]
Computing alignments...  [32.588s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.204s]
Computing alignments...  [32.322s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.279s]
Computing alignments...  [33.407s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.319s]
Computing alignments...  [33.529s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.051s]
Sorting trace points...  [0.982s]
Computing alignments...  [34.094s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.245s]
Computing alignments...  [33.359s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.115s]
Sorting trace points...  [1.32s]
Computing alignments...  [33.318s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.085s]
Sorting trace points...  [1.149s]
Computing alignments...  [33.386s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.276s]
Computing alignments...  [33.134s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.04s]
Sorting trace points...  [1.297s]
Computing alignments...  [33.415s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.177s]
Computing alignments...  [33.049s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.038s]
Sorting trace points...  [1.245s]
Computing alignments...  [33.465s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.262s]
Computing alignments...  [33.67s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.284s]
Computing alignments...  [33.425s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.28s]
Computing alignments...  [33.081s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [559.412s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [23.782s]
Masking reference...  [24.976s]
Initializing dictionary...  [0.063s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [27.169s]
Allocating buffers...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.075s]
Building query seed array...  [2.171s]
Computing hash join...  [4.26s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [66.299s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [9.992s]
Building query seed array...  [2.473s]
Computing hash join...  [4.245s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [47.487s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [10.739s]
Building query seed array...  [2.667s]
Computing hash join...  [4.149s]
Masking low complexity seeds...  [0.2s]
Searching alignments...  [35.992s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [8.178s]
Building query seed array...  [2.125s]
Computing hash join...  [4.267s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [32.964s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [8.083s]
Building query seed array...  [1.975s]
Computing hash join...  [4.048s]
Masking low complexity seeds...  [0.196s]
Searching alignments...  [33.715s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [9.902s]
Building query seed array...  [2.228s]
Computing hash join...  [4.049s]
Masking low complexity seeds...  [0.196s]
Searching alignments...  [28.1s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [10.688s]
Building query seed array...  [2.33s]
Computing hash join...  [4.032s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [29.7s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [8.284s]
Building query seed array...  [1.84s]
Computing hash join...  [4.091s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [25.171s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.106s]
Clearing query masking...  [1.657s]
Opening temporary output file...  [0.03s]
Computing alignments... Loading trace points...  [11.357s]
Sorting trace points...  [2.177s]
Computing alignments...  [52.019s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.071s]
Sorting trace points...  [2.065s]
Computing alignments...  [52.11s]
Deallocating buffers...  [0.034s]
Loading trace points...  [0.161s]
Sorting trace points...  [1.955s]
Computing alignments...  [53.643s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.122s]
Sorting trace points...  [1.708s]
Computing alignments...  [52.843s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.185s]
Sorting trace points...  [2.121s]
Computing alignments...  [52.63s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.162s]
Sorting trace points...  [1.789s]
Computing alignments...  [52.647s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.15s]
Sorting trace points...  [1.857s]
Computing alignments...  [53.087s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
Sorting trace points...  [2.077s]
Computing alignments...  [52.391s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
 [449.73s]
Deallocating reference...  [0.051s]
Loading reference sequences...  [0.058s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [1921.03s]
 [1921.03s]
Deallocating queries...  [0.058s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [3.698s]
 [4.723s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 18518.5s
Reported 2378030784 pairwise alignments, 2378030784 HSPs.
13487369 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C19_R1.fastp-trim.20230215.fq.gz complete: C19_R1.blastx.meganized.daa

Now MEGANizing C19_R1.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: C19_R1.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 100% (229.4s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.2s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (4,387.1s)
Total reads:       13,487,369
With hits:          13,487,369 
Alignments:      2,366,362,471
Assig. Taxonomy:    12,707,420
Assig. SEED:           104,908
Assig. EGGNOG:          47,010
Assig. GTDB:           354,000
Assig. EC:           2,121,656
Assig. INTERPRO2GO:  1,132,926
MinSupport set to: 6743
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.4s)
Min-supp. changes:       3,603
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (9.1s)
Min-supp. changes:       2,693
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (31.6s)
Binning reads Syncing
100% (0.4s)
Class. Taxonomy:            72
Class. SEED:               485
Class. EGGNOG:           1,712
Class. GTDB:                17
Class. EC:               2,337
Class. INTERPRO2GO:      7,968
Total time:  4,667s
Peak memory: 29.8 of 195.3G
MEGANization of C19_R1.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C19_R2.fastp-trim.20230215.fq.gz...
1c30e365dc345887ae4103c63d265ae1  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C19_R2.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C19_R2.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.307s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.738s]
Opening the output file...  [0s]
Loading query sequences...  [76.918s]
Masking queries...  [19.468s]
Algorithm: Double-indexed
Building query histograms...  [22.525s]
Loading reference sequences...  [29.566s]
Masking reference...  [32.157s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.171s]
Allocating buffers...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.379s]
Building query seed array...  [2.131s]
Computing hash join...  [5.42s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [84.429s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.304s]
Building query seed array...  [2.443s]
Computing hash join...  [5.192s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [58.136s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.873s]
Building query seed array...  [2.608s]
Computing hash join...  [5.221s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [45.106s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.032s]
Building query seed array...  [2.091s]
Computing hash join...  [5.292s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [40.834s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.901s]
Building query seed array...  [1.971s]
Computing hash join...  [5.02s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [45.066s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.64s]
Building query seed array...  [2.238s]
Computing hash join...  [4.978s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [32.559s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.472s]
Building query seed array...  [2.421s]
Computing hash join...  [4.999s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [38.368s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.943s]
Building query seed array...  [1.987s]
Computing hash join...  [4.934s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [31.492s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.633s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.588s]
Sorting trace points...  [1.353s]
Computing alignments...  [32.451s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.213s]
Computing alignments...  [32.463s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.211s]
Computing alignments...  [32.121s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.149s]
Computing alignments...  [33.213s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.309s]
Computing alignments...  [33.858s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.008s]
Computing alignments...  [33.996s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.273s]
Computing alignments...  [33.026s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.26s]
Computing alignments...  [33.127s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.31s]
Computing alignments...  [33.529s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.333s]
Computing alignments...  [34.16s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.055s]
Sorting trace points...  [0.986s]
Computing alignments...  [34.328s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.2s]
Computing alignments...  [33.796s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.298s]
Computing alignments...  [34.326s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.384s]
Computing alignments...  [34.538s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.233s]
Computing alignments...  [34.393s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.123s]
Computing alignments...  [33.915s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
 [564.595s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [34.13s]
Masking reference...  [31.286s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.214s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.596s]
Building query seed array...  [2.162s]
Computing hash join...  [5.312s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [80.31s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.381s]
Building query seed array...  [2.53s]
Computing hash join...  [5.174s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [56.74s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.496s]
Building query seed array...  [2.563s]
Computing hash join...  [5.235s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [45.164s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.382s]
Building query seed array...  [2.246s]
Computing hash join...  [5.208s]
Masking low complexity seeds...  [0.256s]
Searching alignments...  [41.092s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.988s]
Building query seed array...  [1.999s]
Computing hash join...  [5.016s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [43.22s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.445s]
Building query seed array...  [2.26s]
Computing hash join...  [5.016s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [32.49s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.363s]
Building query seed array...  [2.383s]
Computing hash join...  [5.01s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [36.191s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.092s]
Building query seed array...  [1.919s]
Computing hash join...  [5.021s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [32.012s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.665s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.514s]
Sorting trace points...  [1.314s]
Computing alignments...  [32.668s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.135s]
Sorting trace points...  [1.176s]
Computing alignments...  [32.299s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.196s]
Computing alignments...  [31.975s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.053s]
Sorting trace points...  [0.984s]
Computing alignments...  [33.081s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.303s]
Computing alignments...  [33.907s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.3s]
Computing alignments...  [34.293s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.326s]
Computing alignments...  [32.984s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.252s]
Computing alignments...  [33.373s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.084s]
Sorting trace points...  [1.301s]
Computing alignments...  [33.282s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.335s]
Computing alignments...  [33.786s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.334s]
Computing alignments...  [34.238s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.156s]
Computing alignments...  [33.616s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.331s]
Computing alignments...  [34.209s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.079s]
Computing alignments...  [34.341s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.316s]
Computing alignments...  [34.197s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
Sorting trace points...  [1.298s]
Computing alignments...  [33.715s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [563.611s]
Deallocating reference...  [0.065s]
Loading reference sequences...  [29.497s]
Masking reference...  [32.166s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.574s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.313s]
Building query seed array...  [2.139s]
Computing hash join...  [5.185s]
Masking low complexity seeds...  [0.249s]
Searching alignments...  [84.522s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.562s]
Building query seed array...  [2.491s]
Computing hash join...  [5.257s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [57.875s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.293s]
Building query seed array...  [2.607s]
Computing hash join...  [5.272s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [46.408s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.07s]
Building query seed array...  [2.111s]
Computing hash join...  [5.246s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [42.498s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.321s]
Building query seed array...  [1.884s]
Computing hash join...  [4.996s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [45.285s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.619s]
Building query seed array...  [2.226s]
Computing hash join...  [5.079s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [33.386s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.951s]
Building query seed array...  [2.454s]
Computing hash join...  [5.109s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [39.043s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.295s]
Building query seed array...  [1.877s]
Computing hash join...  [5.077s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [31.62s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.138s]
Clearing query masking...  [1.643s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.532s]
Sorting trace points...  [1.29s]
Computing alignments...  [32.454s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.253s]
Computing alignments...  [32.564s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.191s]
Computing alignments...  [32.07s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.318s]
Computing alignments...  [33.094s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.08s]
Computing alignments...  [33.866s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.269s]
Computing alignments...  [34.317s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.264s]
Computing alignments...  [33.112s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.292s]
Computing alignments...  [33.129s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.091s]
Sorting trace points...  [1.318s]
Computing alignments...  [33.321s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.035s]
Computing alignments...  [33.881s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.312s]
Computing alignments...  [33.962s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.267s]
Computing alignments...  [33.599s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.321s]
Computing alignments...  [34.144s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.187s]
Computing alignments...  [34.412s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.33s]
Computing alignments...  [34.135s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.191s]
Computing alignments...  [33.736s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [563.452s]
Deallocating reference...  [0.069s]
Loading reference sequences...  [29.566s]
Masking reference...  [30.892s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.525s]
Allocating buffers...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.509s]
Building query seed array...  [2.099s]
Computing hash join...  [5.273s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [83.552s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.783s]
Building query seed array...  [2.536s]
Computing hash join...  [5.19s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [56.181s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.126s]
Building query seed array...  [2.632s]
Computing hash join...  [5.176s]
Masking low complexity seeds...  [0.259s]
Searching alignments...  [47.572s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.315s]
Building query seed array...  [2.083s]
Computing hash join...  [5.203s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [42.975s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.015s]
Building query seed array...  [1.907s]
Computing hash join...  [5.073s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [45.121s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.432s]
Building query seed array...  [2.303s]
Computing hash join...  [4.963s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [32.801s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.007s]
Building query seed array...  [2.363s]
Computing hash join...  [4.985s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [37.174s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10s]
Building query seed array...  [2.031s]
Computing hash join...  [4.91s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [30.497s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.137s]
Clearing query masking...  [1.574s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.7s]
Sorting trace points...  [1.31s]
Computing alignments...  [32.314s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.236s]
Computing alignments...  [32.161s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.062s]
Computing alignments...  [31.923s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.175s]
Computing alignments...  [32.928s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.273s]
Computing alignments...  [33.553s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.764s]
Computing alignments...  [34.101s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.047s]
Sorting trace points...  [0.936s]
Computing alignments...  [32.966s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.223s]
Computing alignments...  [32.983s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.014s]
Computing alignments...  [33.242s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.036s]
Sorting trace points...  [1.317s]
Computing alignments...  [33.809s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.334s]
Computing alignments...  [34.012s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.284s]
Computing alignments...  [33.554s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.34s]
Computing alignments...  [34.157s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.33s]
Computing alignments...  [34.302s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.023s]
Computing alignments...  [34.132s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.325s]
Computing alignments...  [33.79s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [561.747s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.675s]
Masking reference...  [32.12s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [31.876s]
Allocating buffers...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.409s]
Building query seed array...  [2.144s]
Computing hash join...  [5.129s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [82.455s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.196s]
Building query seed array...  [2.485s]
Computing hash join...  [5.203s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [57.539s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.655s]
Building query seed array...  [2.674s]
Computing hash join...  [5.157s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [45.454s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.98s]
Building query seed array...  [2.173s]
Computing hash join...  [5.274s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [41.785s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.913s]
Building query seed array...  [1.978s]
Computing hash join...  [4.924s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [43.782s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.304s]
Building query seed array...  [2.229s]
Computing hash join...  [4.927s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [33.193s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.387s]
Building query seed array...  [2.355s]
Computing hash join...  [4.912s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [37.167s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.128s]
Building query seed array...  [1.996s]
Computing hash join...  [4.943s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [31.099s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.136s]
Clearing query masking...  [1.619s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.579s]
Sorting trace points...  [1.321s]
Computing alignments...  [32.266s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.23s]
Computing alignments...  [32.126s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.257s]
Computing alignments...  [31.833s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.328s]
Computing alignments...  [32.88s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.115s]
Computing alignments...  [33.492s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.114s]
Computing alignments...  [33.883s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.13s]
Sorting trace points...  [1.256s]
Computing alignments...  [32.976s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.062s]
Sorting trace points...  [0.984s]
Computing alignments...  [32.931s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.088s]
Computing alignments...  [33.241s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.124s]
Computing alignments...  [33.839s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.271s]
Computing alignments...  [34.041s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.032s]
Sorting trace points...  [1.3s]
Computing alignments...  [33.574s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.368s]
Computing alignments...  [34.116s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.005s]
Computing alignments...  [34.213s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.355s]
Computing alignments...  [34.148s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.284s]
Computing alignments...  [33.77s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [560.447s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.581s]
Masking reference...  [30.863s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.408s]
Allocating buffers...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.222s]
Building query seed array...  [2.129s]
Computing hash join...  [5.179s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [80.945s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.4s]
Building query seed array...  [2.444s]
Computing hash join...  [5.26s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [55.922s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.961s]
Building query seed array...  [2.579s]
Computing hash join...  [5.196s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [44.879s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.157s]
Building query seed array...  [2.132s]
Computing hash join...  [5.212s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [39.84s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.141s]
Building query seed array...  [2.024s]
Computing hash join...  [5.026s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [42.908s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.444s]
Building query seed array...  [2.214s]
Computing hash join...  [4.912s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [33.345s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.136s]
Building query seed array...  [2.391s]
Computing hash join...  [4.943s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [35.769s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.841s]
Building query seed array...  [1.971s]
Computing hash join...  [4.96s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [31.174s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.617s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.473s]
Sorting trace points...  [1.31s]
Computing alignments...  [31.933s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.067s]
Sorting trace points...  [0.914s]
Computing alignments...  [31.838s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.159s]
Computing alignments...  [31.582s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.236s]
Computing alignments...  [32.557s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.259s]
Computing alignments...  [33.228s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.107s]
Computing alignments...  [33.435s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.096s]
Sorting trace points...  [1.187s]
Computing alignments...  [32.705s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.284s]
Computing alignments...  [32.499s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.175s]
Computing alignments...  [32.888s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.21s]
Computing alignments...  [33.505s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.311s]
Computing alignments...  [33.78s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.312s]
Computing alignments...  [33.284s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.217s]
Computing alignments...  [33.965s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.085s]
Sorting trace points...  [1.357s]
Computing alignments...  [33.989s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.323s]
Computing alignments...  [33.792s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.276s]
Computing alignments...  [33.48s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
 [555.738s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [31.445s]
Masking reference...  [30.837s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.277s]
Allocating buffers...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.715s]
Building query seed array...  [2.175s]
Computing hash join...  [5.224s]
Masking low complexity seeds...  [0.256s]
Searching alignments...  [81.589s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.3s]
Building query seed array...  [2.424s]
Computing hash join...  [5.204s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [55.832s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.491s]
Building query seed array...  [2.661s]
Computing hash join...  [5.219s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [48.127s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.33s]
Building query seed array...  [2.14s]
Computing hash join...  [5.116s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [43.075s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.575s]
Building query seed array...  [1.943s]
Computing hash join...  [4.99s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [44.072s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.997s]
Building query seed array...  [2.245s]
Computing hash join...  [5.016s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [33s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.009s]
Building query seed array...  [2.321s]
Computing hash join...  [4.997s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [38.183s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.772s]
Building query seed array...  [1.904s]
Computing hash join...  [4.962s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [31.493s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.74s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.493s]
Sorting trace points...  [1.329s]
Computing alignments...  [32.162s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.069s]
Computing alignments...  [32.3s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.219s]
Computing alignments...  [31.888s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.069s]
Sorting trace points...  [0.953s]
Computing alignments...  [32.898s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.28s]
Computing alignments...  [33.64s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.09s]
Sorting trace points...  [1.153s]
Computing alignments...  [34.037s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.259s]
Computing alignments...  [32.932s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.144s]
Computing alignments...  [32.913s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.275s]
Computing alignments...  [33.426s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.181s]
Computing alignments...  [33.881s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.315s]
Computing alignments...  [34.135s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.338s]
Computing alignments...  [33.679s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.127s]
Sorting trace points...  [1.344s]
Computing alignments...  [34.094s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.39s]
Computing alignments...  [34.211s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.086s]
Computing alignments...  [34.194s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [0.998s]
Computing alignments...  [33.892s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [561.336s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [29.636s]
Masking reference...  [32.08s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [31.993s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.068s]
Building query seed array...  [2.227s]
Computing hash join...  [5.243s]
Masking low complexity seeds...  [0.256s]
Searching alignments...  [82.021s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.206s]
Building query seed array...  [2.435s]
Computing hash join...  [5.222s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [56.962s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.349s]
Building query seed array...  [2.629s]
Computing hash join...  [5.165s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [46.321s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.449s]
Building query seed array...  [2.083s]
Computing hash join...  [5.21s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [40.122s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.629s]
Building query seed array...  [1.942s]
Computing hash join...  [4.979s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [43.713s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.023s]
Building query seed array...  [2.368s]
Computing hash join...  [5.021s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [32.472s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.114s]
Building query seed array...  [2.378s]
Computing hash join...  [5.026s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [36.902s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.411s]
Building query seed array...  [1.927s]
Computing hash join...  [4.959s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [30.918s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.649s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.552s]
Sorting trace points...  [1.31s]
Computing alignments...  [32.268s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.215s]
Computing alignments...  [32.199s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.199s]
Computing alignments...  [31.818s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.282s]
Computing alignments...  [32.869s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.104s]
Sorting trace points...  [1.282s]
Computing alignments...  [33.457s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.269s]
Computing alignments...  [33.937s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.258s]
Computing alignments...  [32.753s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.27s]
Computing alignments...  [32.845s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [0.998s]
Computing alignments...  [33.188s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.308s]
Computing alignments...  [33.769s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.339s]
Computing alignments...  [33.995s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.366s]
Computing alignments...  [33.562s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.365s]
Computing alignments...  [34.063s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.339s]
Computing alignments...  [34.165s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.351s]
Computing alignments...  [34.051s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.008s]
Computing alignments...  [33.695s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [560.415s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.53s]
Masking reference...  [31.038s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.676s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.464s]
Building query seed array...  [2.127s]
Computing hash join...  [5.184s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [83.794s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.27s]
Building query seed array...  [2.43s]
Computing hash join...  [5.207s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [57.649s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.035s]
Building query seed array...  [2.574s]
Computing hash join...  [5.205s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [46.218s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.517s]
Building query seed array...  [2.198s]
Computing hash join...  [5.133s]
Masking low complexity seeds...  [0.259s]
Searching alignments...  [42.137s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.295s]
Building query seed array...  [1.946s]
Computing hash join...  [4.984s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [44.224s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.584s]
Building query seed array...  [2.22s]
Computing hash join...  [4.971s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [33.997s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.2s]
Building query seed array...  [2.354s]
Computing hash join...  [5.033s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [37.194s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.671s]
Building query seed array...  [1.963s]
Computing hash join...  [4.965s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [32.184s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.128s]
Clearing query masking...  [1.619s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.496s]
Sorting trace points...  [1.308s]
Computing alignments...  [32.288s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.569s]
Sorting trace points...  [1.154s]
Computing alignments...  [32.176s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.044s]
Sorting trace points...  [0.902s]
Computing alignments...  [31.857s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.263s]
Computing alignments...  [32.854s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.278s]
Computing alignments...  [33.388s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.308s]
Computing alignments...  [33.895s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.07s]
Sorting trace points...  [0.944s]
Computing alignments...  [32.747s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.018s]
Computing alignments...  [32.786s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.262s]
Computing alignments...  [33.234s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.285s]
Computing alignments...  [33.653s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.324s]
Computing alignments...  [33.894s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.287s]
Computing alignments...  [33.517s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.118s]
Computing alignments...  [34.14s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.312s]
Computing alignments...  [34.217s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.237s]
Computing alignments...  [34.058s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.298s]
Computing alignments...  [33.707s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [559.738s]
Deallocating reference...  [0.063s]
Loading reference sequences...  [29.477s]
Masking reference...  [30.848s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.577s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.607s]
Building query seed array...  [2.15s]
Computing hash join...  [5.247s]
Masking low complexity seeds...  [0.256s]
Searching alignments...  [83.453s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.332s]
Building query seed array...  [2.488s]
Computing hash join...  [5.406s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [55.999s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [14.086s]
Building query seed array...  [2.589s]
Computing hash join...  [5.172s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [47.762s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.925s]
Building query seed array...  [2.058s]
Computing hash join...  [5.117s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [40.294s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.037s]
Building query seed array...  [1.974s]
Computing hash join...  [5.031s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [44.544s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.496s]
Building query seed array...  [2.246s]
Computing hash join...  [4.941s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [33.376s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.05s]
Building query seed array...  [2.4s]
Computing hash join...  [5.01s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [38.157s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.783s]
Building query seed array...  [1.926s]
Computing hash join...  [5.016s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [31.149s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.128s]
Clearing query masking...  [1.588s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.502s]
Sorting trace points...  [1.312s]
Computing alignments...  [32.246s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.152s]
Computing alignments...  [32.196s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.226s]
Computing alignments...  [31.853s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.257s]
Computing alignments...  [32.872s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.199s]
Computing alignments...  [33.451s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.012s]
Computing alignments...  [33.864s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.27s]
Computing alignments...  [32.829s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.002s]
Sorting trace points...  [1.05s]
Computing alignments...  [32.839s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.26s]
Computing alignments...  [33.238s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.222s]
Computing alignments...  [33.824s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.331s]
Computing alignments...  [33.979s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.143s]
Computing alignments...  [33.557s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.985s]
Sorting trace points...  [1.327s]
Computing alignments...  [34.104s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.347s]
Computing alignments...  [34.171s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.306s]
Computing alignments...  [34.148s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.309s]
Computing alignments...  [33.788s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
 [561.205s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [30.546s]
Masking reference...  [30.836s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.539s]
Allocating buffers...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.06s]
Building query seed array...  [2.078s]
Computing hash join...  [5.198s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [81.49s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.434s]
Building query seed array...  [2.492s]
Computing hash join...  [5.236s]
Masking low complexity seeds...  [0.256s]
Searching alignments...  [57.129s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.495s]
Building query seed array...  [2.554s]
Computing hash join...  [5.157s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [44.498s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.881s]
Building query seed array...  [2.178s]
Computing hash join...  [5.239s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [39.559s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.081s]
Building query seed array...  [2.035s]
Computing hash join...  [5.069s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [43.192s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.274s]
Building query seed array...  [2.268s]
Computing hash join...  [4.969s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [32.668s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.399s]
Building query seed array...  [2.381s]
Computing hash join...  [4.977s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [36.654s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.821s]
Building query seed array...  [1.947s]
Computing hash join...  [5.03s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [30.882s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.137s]
Clearing query masking...  [1.639s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.603s]
Sorting trace points...  [1.287s]
Computing alignments...  [32.186s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.23s]
Computing alignments...  [32.236s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.234s]
Computing alignments...  [31.808s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.255s]
Computing alignments...  [33.142s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.575s]
Sorting trace points...  [1.159s]
Computing alignments...  [33.965s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.278s]
Computing alignments...  [34.823s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.039s]
Sorting trace points...  [1.295s]
Computing alignments...  [33.045s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.093s]
Sorting trace points...  [1.249s]
Computing alignments...  [33.209s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.303s]
Computing alignments...  [33.142s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.091s]
Sorting trace points...  [1.159s]
Computing alignments...  [33.736s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.045s]
Sorting trace points...  [0.976s]
Computing alignments...  [34.103s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.042s]
Sorting trace points...  [1.304s]
Computing alignments...  [33.494s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.162s]
Computing alignments...  [33.986s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.33s]
Computing alignments...  [34.312s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.04s]
Sorting trace points...  [1.044s]
Computing alignments...  [34.128s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
Sorting trace points...  [1.314s]
Computing alignments...  [33.652s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
 [562.863s]
Deallocating reference...  [0.063s]
Loading reference sequences...  [29.653s]
Masking reference...  [32.192s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [31.873s]
Allocating buffers...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.584s]
Building query seed array...  [2.147s]
Computing hash join...  [5.176s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [82.139s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.397s]
Building query seed array...  [2.47s]
Computing hash join...  [5.251s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [58.032s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.204s]
Building query seed array...  [2.647s]
Computing hash join...  [5.16s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [47.027s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.707s]
Building query seed array...  [2.188s]
Computing hash join...  [5.166s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [40.926s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.962s]
Building query seed array...  [1.961s]
Computing hash join...  [4.991s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [44.16s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.165s]
Building query seed array...  [2.167s]
Computing hash join...  [4.975s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [32.507s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.67s]
Building query seed array...  [2.399s]
Computing hash join...  [4.979s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [38.42s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.897s]
Building query seed array...  [1.988s]
Computing hash join...  [4.963s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [31.993s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.595s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.589s]
Sorting trace points...  [1.313s]
Computing alignments...  [32.059s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.108s]
Sorting trace points...  [1.291s]
Computing alignments...  [32.166s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.001s]
Computing alignments...  [31.838s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.055s]
Sorting trace points...  [0.975s]
Computing alignments...  [32.715s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.279s]
Computing alignments...  [33.146s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.283s]
Computing alignments...  [33.765s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.035s]
Computing alignments...  [32.606s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.227s]
Computing alignments...  [32.644s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.122s]
Sorting trace points...  [1.293s]
Computing alignments...  [33.234s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.042s]
Sorting trace points...  [1.33s]
Computing alignments...  [33.847s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.123s]
Computing alignments...  [33.903s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.268s]
Computing alignments...  [33.565s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.366s]
Computing alignments...  [34.015s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.33s]
Computing alignments...  [34.167s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.315s]
Computing alignments...  [33.98s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.299s]
Computing alignments...  [33.684s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
 [558.966s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [31.453s]
Masking reference...  [30.847s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.319s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.28s]
Building query seed array...  [2.245s]
Computing hash join...  [5.265s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [84.586s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.625s]
Building query seed array...  [2.476s]
Computing hash join...  [5.199s]
Masking low complexity seeds...  [0.259s]
Searching alignments...  [56.285s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [12.976s]
Building query seed array...  [2.644s]
Computing hash join...  [5.116s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [47.583s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.005s]
Building query seed array...  [2.086s]
Computing hash join...  [5.146s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [42.234s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.247s]
Building query seed array...  [1.885s]
Computing hash join...  [4.997s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [44.177s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.5s]
Building query seed array...  [2.192s]
Computing hash join...  [5.052s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [33.264s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.247s]
Building query seed array...  [2.346s]
Computing hash join...  [4.994s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [38.556s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.75s]
Building query seed array...  [1.881s]
Computing hash join...  [5.063s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [32.084s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.127s]
Clearing query masking...  [1.678s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.588s]
Sorting trace points...  [1.335s]
Computing alignments...  [32.45s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.127s]
Sorting trace points...  [1.297s]
Computing alignments...  [32.361s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.108s]
Computing alignments...  [31.863s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.577s]
Computing alignments...  [33.007s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.3s]
Computing alignments...  [33.697s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.3s]
Computing alignments...  [34.117s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.207s]
Computing alignments...  [32.969s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.031s]
Sorting trace points...  [1.219s]
Computing alignments...  [33.026s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.252s]
Computing alignments...  [33.251s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.001s]
Sorting trace points...  [0.966s]
Computing alignments...  [33.766s]
Deallocating buffers...  [0.022s]
Loading trace points...  [1.058s]
Sorting trace points...  [1.346s]
Computing alignments...  [34.048s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.319s]
Computing alignments...  [33.567s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.29s]
Computing alignments...  [34.068s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.34s]
Computing alignments...  [34.287s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.31s]
Computing alignments...  [34.388s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0s]
Sorting trace points...  [1.122s]
Computing alignments...  [33.721s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [563.572s]
Deallocating reference...  [0.057s]
Loading reference sequences...  [23.638s]
Masking reference...  [24.993s]
Initializing dictionary...  [0.062s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [26.206s]
Allocating buffers...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.533s]
Building query seed array...  [2.107s]
Computing hash join...  [4.312s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [65.244s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [10.522s]
Building query seed array...  [2.542s]
Computing hash join...  [4.306s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [45.306s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [11.038s]
Building query seed array...  [2.62s]
Computing hash join...  [4.318s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [38.05s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [8.27s]
Building query seed array...  [2.182s]
Computing hash join...  [4.344s]
Masking low complexity seeds...  [0.249s]
Searching alignments...  [32.426s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [8.21s]
Building query seed array...  [2.003s]
Computing hash join...  [4.226s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [34.969s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [10.179s]
Building query seed array...  [2.268s]
Computing hash join...  [4.151s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [26.681s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [10.373s]
Building query seed array...  [2.347s]
Computing hash join...  [4.133s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [31.487s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [8.1s]
Building query seed array...  [1.973s]
Computing hash join...  [4.153s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [25.373s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.109s]
Clearing query masking...  [1.647s]
Opening temporary output file...  [0.029s]
Computing alignments... Loading trace points...  [10.204s]
Sorting trace points...  [2.111s]
Computing alignments...  [51.225s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.115s]
Sorting trace points...  [1.653s]
Computing alignments...  [51.378s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.094s]
Sorting trace points...  [1.709s]
Computing alignments...  [53.397s]
Deallocating buffers...  [0.035s]
Loading trace points...  [0.16s]
Sorting trace points...  [2.063s]
Computing alignments...  [52.146s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.082s]
Sorting trace points...  [2.139s]
Computing alignments...  [53.107s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.149s]
Sorting trace points...  [1.793s]
Computing alignments...  [53.645s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.154s]
Sorting trace points...  [1.77s]
Computing alignments...  [54.174s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0s]
Sorting trace points...  [2.131s]
Computing alignments...  [53.524s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
 [449.635s]
Deallocating reference...  [0.051s]
Loading reference sequences...  [0.084s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [1930.58s]
 [1930.58s]
Deallocating queries...  [0.07s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [3.627s]
 [4.689s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 18394.3s
Reported 2330532887 pairwise alignments, 2330532887 HSPs.
13807024 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C19_R2.fastp-trim.20230215.fq.gz complete: C19_R2.blastx.meganized.daa

Now MEGANizing C19_R2.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: C19_R2.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 100% (235.4s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.1s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (4,272.5s)
Total reads:       13,807,024
With hits:          13,807,024 
Alignments:      2,320,473,708
Assig. Taxonomy:    12,981,827
Assig. SEED:           102,227
Assig. EGGNOG:          46,317
Assig. GTDB:           348,272
Assig. EC:           2,158,084
Assig. INTERPRO2GO:  1,133,684
MinSupport set to: 6903
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.5s)
Min-supp. changes:       3,725
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (8.6s)
Min-supp. changes:       2,828
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (29.8s)
Binning reads Syncing
100% (0.4s)
Class. Taxonomy:            73
Class. SEED:               482
Class. EGGNOG:           1,717
Class. GTDB:                16
Class. EC:               2,317
Class. INTERPRO2GO:      8,037
Total time:  4,556s
Peak memory: 29.9 of 195.3G
MEGANization of C19_R2.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C20_R1.fastp-trim.20230215.fq.gz...
0525a384c0b5cbcceb261e1d81f2b100  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C20_R1.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C20_R1.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.315s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.698s]
Opening the output file...  [0s]
Loading query sequences...  [74.019s]
Masking queries...  [18.924s]
Algorithm: Double-indexed
Building query histograms...  [18.135s]
Loading reference sequences...  [29.683s]
Masking reference...  [32.065s]
Initializing dictionary...  [0.08s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.733s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.064s]
Building query seed array...  [2.037s]
Computing hash join...  [5.133s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [81.338s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.673s]
Building query seed array...  [2.418s]
Computing hash join...  [5.246s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [52.106s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.75s]
Building query seed array...  [2.545s]
Computing hash join...  [5.091s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [45.868s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.034s]
Building query seed array...  [2.017s]
Computing hash join...  [5.167s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [41.724s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.289s]
Building query seed array...  [1.852s]
Computing hash join...  [4.924s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [40.18s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.664s]
Building query seed array...  [2.106s]
Computing hash join...  [4.935s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [32.597s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.102s]
Building query seed array...  [2.284s]
Computing hash join...  [4.908s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [35.711s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.003s]
Building query seed array...  [1.917s]
Computing hash join...  [4.938s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [30.279s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.626s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.343s]
Sorting trace points...  [1.27s]
Computing alignments...  [32.061s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.084s]
Sorting trace points...  [1.238s]
Computing alignments...  [32.487s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.239s]
Sorting trace points...  [1.092s]
Computing alignments...  [32.151s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.254s]
Computing alignments...  [33.24s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.063s]
Sorting trace points...  [0.973s]
Computing alignments...  [33.544s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.095s]
Sorting trace points...  [1.211s]
Computing alignments...  [33.723s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [1.247s]
Computing alignments...  [32.9s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.127s]
Computing alignments...  [33.038s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.242s]
Computing alignments...  [32.786s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.157s]
Computing alignments...  [32.626s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.258s]
Computing alignments...  [32.863s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.1s]
Sorting trace points...  [1.253s]
Computing alignments...  [32.77s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.039s]
Sorting trace points...  [1.246s]
Computing alignments...  [32.782s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.237s]
Computing alignments...  [33.104s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.288s]
Computing alignments...  [33.071s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.022s]
Computing alignments...  [32.535s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [552.574s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.69s]
Masking reference...  [32.133s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.829s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.275s]
Building query seed array...  [2.083s]
Computing hash join...  [5.13s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [79.269s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.424s]
Building query seed array...  [2.433s]
Computing hash join...  [5.066s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [53.514s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.816s]
Building query seed array...  [2.467s]
Computing hash join...  [5.01s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [44.155s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.911s]
Building query seed array...  [2.024s]
Computing hash join...  [5.134s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [40.869s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.86s]
Building query seed array...  [1.891s]
Computing hash join...  [4.861s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [40.348s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.794s]
Building query seed array...  [2.13s]
Computing hash join...  [4.847s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [33.653s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.063s]
Building query seed array...  [2.247s]
Computing hash join...  [4.903s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [36.049s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.168s]
Building query seed array...  [1.876s]
Computing hash join...  [4.944s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [29.75s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.554s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.335s]
Sorting trace points...  [1.271s]
Computing alignments...  [31.654s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.186s]
Computing alignments...  [32.089s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.002s]
Sorting trace points...  [1.247s]
Computing alignments...  [31.733s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.259s]
Computing alignments...  [32.815s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.239s]
Computing alignments...  [33.362s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.054s]
Sorting trace points...  [0.953s]
Computing alignments...  [33.471s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.211s]
Computing alignments...  [32.601s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.234s]
Computing alignments...  [32.585s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.243s]
Computing alignments...  [32.435s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.084s]
Sorting trace points...  [1.291s]
Computing alignments...  [32.352s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.234s]
Computing alignments...  [32.701s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.259s]
Computing alignments...  [32.638s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.246s]
Computing alignments...  [32.669s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.289s]
Computing alignments...  [32.936s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.212s]
Computing alignments...  [33.013s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.03s]
Computing alignments...  [32.363s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [548.433s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [29.445s]
Masking reference...  [30.851s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [33.239s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.241s]
Building query seed array...  [2.056s]
Computing hash join...  [5s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [80.807s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.116s]
Building query seed array...  [2.374s]
Computing hash join...  [5.011s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [53.496s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.705s]
Building query seed array...  [2.598s]
Computing hash join...  [5.103s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [44.826s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.928s]
Building query seed array...  [2.049s]
Computing hash join...  [5.1s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [40.496s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.989s]
Building query seed array...  [1.84s]
Computing hash join...  [4.898s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [40.702s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.667s]
Building query seed array...  [2.166s]
Computing hash join...  [4.883s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [33.333s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.378s]
Building query seed array...  [2.298s]
Computing hash join...  [4.81s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [35.313s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.585s]
Building query seed array...  [1.83s]
Computing hash join...  [4.923s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [30.825s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.135s]
Clearing query masking...  [1.582s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.484s]
Sorting trace points...  [1.274s]
Computing alignments...  [31.864s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.16s]
Computing alignments...  [32.324s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.257s]
Computing alignments...  [31.825s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.267s]
Computing alignments...  [33.165s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.261s]
Computing alignments...  [33.407s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.098s]
Sorting trace points...  [1.271s]
Computing alignments...  [33.624s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.224s]
Computing alignments...  [32.834s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.254s]
Computing alignments...  [32.75s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.29s]
Computing alignments...  [32.785s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.246s]
Computing alignments...  [32.457s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.091s]
Sorting trace points...  [1.221s]
Computing alignments...  [32.76s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.225s]
Sorting trace points...  [1.163s]
Computing alignments...  [32.612s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.088s]
Sorting trace points...  [1.188s]
Computing alignments...  [32.753s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.164s]
Computing alignments...  [32.866s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.202s]
Computing alignments...  [32.859s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [0.989s]
Computing alignments...  [32.328s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [550.555s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [30.018s]
Masking reference...  [31.01s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.452s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [9.941s]
Building query seed array...  [2.108s]
Computing hash join...  [5.1s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [78.749s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.54s]
Building query seed array...  [2.38s]
Computing hash join...  [5.017s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [52.631s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.372s]
Building query seed array...  [2.565s]
Computing hash join...  [5.038s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [43.729s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.167s]
Building query seed array...  [1.995s]
Computing hash join...  [5.025s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [39.912s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.967s]
Building query seed array...  [1.833s]
Computing hash join...  [4.926s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [39.675s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.275s]
Building query seed array...  [2.187s]
Computing hash join...  [4.861s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [32.562s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.294s]
Building query seed array...  [2.402s]
Computing hash join...  [4.938s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [35.154s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.834s]
Building query seed array...  [1.862s]
Computing hash join...  [4.926s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [30.709s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.524s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.401s]
Sorting trace points...  [1.285s]
Computing alignments...  [31.935s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.066s]
Sorting trace points...  [0.98s]
Computing alignments...  [32.277s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.176s]
Computing alignments...  [31.969s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.253s]
Computing alignments...  [33.101s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.243s]
Computing alignments...  [33.432s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.084s]
Sorting trace points...  [1.326s]
Computing alignments...  [33.636s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.156s]
Computing alignments...  [32.841s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.288s]
Computing alignments...  [32.922s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.249s]
Computing alignments...  [32.842s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.249s]
Computing alignments...  [32.635s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.088s]
Sorting trace points...  [0.981s]
Computing alignments...  [32.908s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.05s]
Computing alignments...  [32.752s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.04s]
Sorting trace points...  [1.217s]
Computing alignments...  [32.814s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.287s]
Computing alignments...  [33.034s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.248s]
Computing alignments...  [32.998s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.235s]
Computing alignments...  [32.497s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [551.531s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [29.714s]
Masking reference...  [32.138s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.204s]
Allocating buffers...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.037s]
Building query seed array...  [2.046s]
Computing hash join...  [5.045s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [79.516s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.065s]
Building query seed array...  [2.421s]
Computing hash join...  [5.099s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [51.45s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.634s]
Building query seed array...  [2.52s]
Computing hash join...  [5.146s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [43.31s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.74s]
Building query seed array...  [2.048s]
Computing hash join...  [5.123s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [38.997s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.092s]
Building query seed array...  [1.869s]
Computing hash join...  [4.885s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [39.944s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.196s]
Building query seed array...  [2.167s]
Computing hash join...  [4.823s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [31.787s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.31s]
Building query seed array...  [2.275s]
Computing hash join...  [4.846s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [35.347s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.855s]
Building query seed array...  [1.879s]
Computing hash join...  [4.915s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [29.963s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.53s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.358s]
Sorting trace points...  [1.242s]
Computing alignments...  [31.589s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.224s]
Computing alignments...  [32.131s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.242s]
Computing alignments...  [31.864s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.123s]
Computing alignments...  [33.173s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.096s]
Sorting trace points...  [1.244s]
Computing alignments...  [33.34s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.023s]
Computing alignments...  [33.707s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.078s]
Sorting trace points...  [0.991s]
Computing alignments...  [32.851s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.095s]
Computing alignments...  [32.826s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.138s]
Computing alignments...  [32.667s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.246s]
Computing alignments...  [32.444s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.237s]
Computing alignments...  [32.747s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.286s]
Computing alignments...  [32.606s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.291s]
Computing alignments...  [32.593s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.039s]
Sorting trace points...  [0.991s]
Computing alignments...  [32.957s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.165s]
Computing alignments...  [32.907s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.221s]
Computing alignments...  [32.394s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [549.276s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [29.81s]
Masking reference...  [32.13s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.529s]
Allocating buffers...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.499s]
Building query seed array...  [2.155s]
Computing hash join...  [5.146s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [77.776s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.691s]
Building query seed array...  [2.347s]
Computing hash join...  [5.175s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [53.064s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.621s]
Building query seed array...  [2.509s]
Computing hash join...  [4.999s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [43.006s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.418s]
Building query seed array...  [2.067s]
Computing hash join...  [5.072s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [40.176s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.193s]
Building query seed array...  [1.845s]
Computing hash join...  [4.938s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [38.94s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.234s]
Building query seed array...  [2.145s]
Computing hash join...  [4.892s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [32.019s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.147s]
Building query seed array...  [2.27s]
Computing hash join...  [4.845s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [34.69s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.891s]
Building query seed array...  [1.923s]
Computing hash join...  [4.903s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [29.073s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.142s]
Clearing query masking...  [1.622s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.264s]
Sorting trace points...  [1.262s]
Computing alignments...  [31.381s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.2s]
Computing alignments...  [31.854s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.203s]
Computing alignments...  [31.59s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.101s]
Computing alignments...  [32.722s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.896s]
Sorting trace points...  [1.259s]
Computing alignments...  [33.021s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.242s]
Computing alignments...  [33.087s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.248s]
Computing alignments...  [32.386s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.248s]
Computing alignments...  [32.427s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.236s]
Computing alignments...  [32.327s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.246s]
Computing alignments...  [32.251s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.244s]
Computing alignments...  [32.544s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.266s]
Computing alignments...  [32.465s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.084s]
Sorting trace points...  [0.978s]
Computing alignments...  [32.456s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.248s]
Computing alignments...  [32.684s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.215s]
Computing alignments...  [32.656s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.036s]
Computing alignments...  [32.152s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [545.606s]
Deallocating reference...  [0.07s]
Loading reference sequences...  [29.631s]
Masking reference...  [32.134s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.139s]
Allocating buffers...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.254s]
Building query seed array...  [2.147s]
Computing hash join...  [5.106s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [80.583s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.376s]
Building query seed array...  [2.407s]
Computing hash join...  [5.127s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [54.06s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.36s]
Building query seed array...  [2.516s]
Computing hash join...  [5.014s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [44.813s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.051s]
Building query seed array...  [2.046s]
Computing hash join...  [5.201s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [41.106s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.932s]
Building query seed array...  [1.835s]
Computing hash join...  [4.983s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [40.676s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.517s]
Building query seed array...  [2.195s]
Computing hash join...  [4.961s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [33.142s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.201s]
Building query seed array...  [2.274s]
Computing hash join...  [4.857s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [35.382s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.789s]
Building query seed array...  [1.93s]
Computing hash join...  [4.884s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [30.175s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.134s]
Clearing query masking...  [1.641s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.791s]
Sorting trace points...  [1.267s]
Computing alignments...  [31.771s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.259s]
Computing alignments...  [32.427s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.056s]
Sorting trace points...  [0.951s]
Computing alignments...  [32.093s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.061s]
Sorting trace points...  [0.909s]
Computing alignments...  [33.156s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.28s]
Computing alignments...  [33.591s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.294s]
Computing alignments...  [33.641s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.108s]
Computing alignments...  [32.907s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.254s]
Computing alignments...  [32.801s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.235s]
Computing alignments...  [32.653s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.211s]
Computing alignments...  [32.554s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.248s]
Computing alignments...  [32.834s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.114s]
Sorting trace points...  [1.22s]
Computing alignments...  [32.738s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.24s]
Computing alignments...  [32.756s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.048s]
Sorting trace points...  [0.991s]
Computing alignments...  [33.06s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.06s]
Sorting trace points...  [0.993s]
Computing alignments...  [32.944s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.236s]
Computing alignments...  [32.489s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
 [551.149s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [29.558s]
Masking reference...  [30.86s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.03s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.327s]
Building query seed array...  [2.106s]
Computing hash join...  [5.112s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [78.232s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.73s]
Building query seed array...  [2.368s]
Computing hash join...  [5.14s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [53.652s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.869s]
Building query seed array...  [2.495s]
Computing hash join...  [5.009s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [45.74s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.896s]
Building query seed array...  [1.989s]
Computing hash join...  [4.998s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [40.278s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.168s]
Building query seed array...  [1.883s]
Computing hash join...  [4.889s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [40.49s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.013s]
Building query seed array...  [2.169s]
Computing hash join...  [4.843s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [32.382s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.255s]
Building query seed array...  [2.265s]
Computing hash join...  [4.852s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [36.893s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.82s]
Building query seed array...  [1.847s]
Computing hash join...  [4.832s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [30.106s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.609s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.466s]
Sorting trace points...  [1.319s]
Computing alignments...  [31.679s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.272s]
Computing alignments...  [32.262s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.273s]
Computing alignments...  [32.039s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.268s]
Computing alignments...  [33.094s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.276s]
Computing alignments...  [33.369s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.007s]
Computing alignments...  [33.699s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.239s]
Computing alignments...  [32.801s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.255s]
Computing alignments...  [32.904s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.027s]
Computing alignments...  [32.826s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.251s]
Computing alignments...  [32.613s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.032s]
Computing alignments...  [32.811s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.31s]
Computing alignments...  [32.693s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.246s]
Computing alignments...  [32.725s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.253s]
Computing alignments...  [32.992s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.193s]
Computing alignments...  [32.969s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.232s]
Computing alignments...  [32.398s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
 [551.013s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [29.615s]
Masking reference...  [30.846s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.812s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.456s]
Building query seed array...  [2.047s]
Computing hash join...  [5.099s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [79.581s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.638s]
Building query seed array...  [2.436s]
Computing hash join...  [5.133s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [52.496s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.292s]
Building query seed array...  [2.461s]
Computing hash join...  [5.021s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [43.69s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.071s]
Building query seed array...  [2.042s]
Computing hash join...  [5.175s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [39.522s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.065s]
Building query seed array...  [1.834s]
Computing hash join...  [4.919s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [39.644s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.202s]
Building query seed array...  [2.218s]
Computing hash join...  [4.884s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [32.603s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.896s]
Building query seed array...  [2.28s]
Computing hash join...  [4.812s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [35.513s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.859s]
Building query seed array...  [1.889s]
Computing hash join...  [4.837s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [30.542s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.619s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.344s]
Sorting trace points...  [1.26s]
Computing alignments...  [31.745s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.263s]
Computing alignments...  [32.156s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.214s]
Computing alignments...  [31.891s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.286s]
Computing alignments...  [33.007s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.198s]
Computing alignments...  [33.241s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.115s]
Sorting trace points...  [1.294s]
Computing alignments...  [33.567s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.275s]
Computing alignments...  [32.693s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.258s]
Computing alignments...  [32.743s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.26s]
Computing alignments...  [32.612s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.236s]
Computing alignments...  [32.428s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.259s]
Computing alignments...  [32.695s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.263s]
Computing alignments...  [32.595s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.235s]
Computing alignments...  [32.641s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.115s]
Computing alignments...  [32.905s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.248s]
Computing alignments...  [32.906s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.231s]
Computing alignments...  [32.39s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [549.871s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [29.702s]
Masking reference...  [32.146s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.459s]
Allocating buffers...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.352s]
Building query seed array...  [2.104s]
Computing hash join...  [5.099s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [81.669s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.424s]
Building query seed array...  [2.396s]
Computing hash join...  [5.026s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [52.245s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.215s]
Building query seed array...  [2.522s]
Computing hash join...  [5.047s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [43.939s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.152s]
Building query seed array...  [2s]
Computing hash join...  [5.134s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [39.471s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.234s]
Building query seed array...  [1.827s]
Computing hash join...  [4.994s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [40.632s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.408s]
Building query seed array...  [2.143s]
Computing hash join...  [4.911s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [32.443s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [14.209s]
Building query seed array...  [2.285s]
Computing hash join...  [4.849s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [35.035s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.108s]
Building query seed array...  [1.855s]
Computing hash join...  [4.799s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [29.772s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.575s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.33s]
Sorting trace points...  [1.279s]
Computing alignments...  [31.627s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.257s]
Computing alignments...  [32.134s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.213s]
Computing alignments...  [31.867s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.137s]
Computing alignments...  [33.105s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.095s]
Sorting trace points...  [0.945s]
Computing alignments...  [33.374s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.329s]
Computing alignments...  [33.658s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.333s]
Sorting trace points...  [1.296s]
Computing alignments...  [32.737s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.022s]
Computing alignments...  [32.742s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.146s]
Computing alignments...  [32.659s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.244s]
Computing alignments...  [32.445s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.231s]
Computing alignments...  [32.737s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.105s]
Computing alignments...  [32.607s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.251s]
Computing alignments...  [32.618s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.244s]
Computing alignments...  [32.857s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.104s]
Computing alignments...  [32.871s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.123s]
Computing alignments...  [32.359s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [549.169s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [30.116s]
Masking reference...  [31.326s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.891s]
Allocating buffers...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.388s]
Building query seed array...  [2.123s]
Computing hash join...  [5.196s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [77.356s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.478s]
Building query seed array...  [2.359s]
Computing hash join...  [5.249s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [52.396s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.339s]
Building query seed array...  [2.554s]
Computing hash join...  [5.134s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [44.412s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.997s]
Building query seed array...  [2.004s]
Computing hash join...  [4.994s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [38.904s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.109s]
Building query seed array...  [1.841s]
Computing hash join...  [4.925s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [39.399s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.11s]
Building query seed array...  [2.185s]
Computing hash join...  [4.821s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [32.458s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.127s]
Building query seed array...  [2.276s]
Computing hash join...  [4.837s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [34.885s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.669s]
Building query seed array...  [1.906s]
Computing hash join...  [4.866s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [29.677s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.576s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.447s]
Sorting trace points...  [1.273s]
Computing alignments...  [31.708s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.061s]
Sorting trace points...  [0.97s]
Computing alignments...  [32.223s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
Sorting trace points...  [0.918s]
Computing alignments...  [32.413s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.245s]
Computing alignments...  [33.091s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.198s]
Computing alignments...  [33.478s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.287s]
Computing alignments...  [33.813s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.088s]
Computing alignments...  [32.877s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.233s]
Computing alignments...  [32.91s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.271s]
Computing alignments...  [32.723s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.157s]
Computing alignments...  [32.414s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.228s]
Computing alignments...  [32.857s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.054s]
Sorting trace points...  [0.97s]
Computing alignments...  [32.706s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.254s]
Computing alignments...  [32.655s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [0.983s]
Computing alignments...  [32.958s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.229s]
Computing alignments...  [32.951s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.189s]
Computing alignments...  [32.347s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [550.206s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.636s]
Masking reference...  [30.865s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.735s]
Allocating buffers...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.05s]
Building query seed array...  [1.945s]
Computing hash join...  [5.153s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [81.042s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.633s]
Building query seed array...  [2.397s]
Computing hash join...  [5.189s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [53.377s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.524s]
Building query seed array...  [2.537s]
Computing hash join...  [5.02s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [46.064s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.374s]
Building query seed array...  [2.04s]
Computing hash join...  [5.147s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [40.973s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.038s]
Building query seed array...  [1.833s]
Computing hash join...  [4.905s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [39.804s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.14s]
Building query seed array...  [2.132s]
Computing hash join...  [4.893s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [33.01s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [14.009s]
Building query seed array...  [2.309s]
Computing hash join...  [4.931s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [35.172s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.902s]
Building query seed array...  [1.877s]
Computing hash join...  [4.85s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [30.188s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.142s]
Clearing query masking...  [1.627s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.408s]
Sorting trace points...  [1.283s]
Computing alignments...  [31.64s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.084s]
Sorting trace points...  [1.22s]
Computing alignments...  [32.201s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.236s]
Computing alignments...  [31.758s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.073s]
Sorting trace points...  [0.907s]
Computing alignments...  [32.868s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.003s]
Sorting trace points...  [1.256s]
Computing alignments...  [33.063s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.066s]
Computing alignments...  [33.349s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.092s]
Sorting trace points...  [1.243s]
Computing alignments...  [32.598s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.239s]
Computing alignments...  [32.634s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.28s]
Computing alignments...  [32.424s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.234s]
Computing alignments...  [32.488s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.253s]
Computing alignments...  [32.705s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.254s]
Computing alignments...  [32.576s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.015s]
Computing alignments...  [32.605s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.258s]
Computing alignments...  [32.856s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.255s]
Computing alignments...  [32.811s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.218s]
Computing alignments...  [32.364s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
 [547.937s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.404s]
Masking reference...  [30.894s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [33.212s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.435s]
Building query seed array...  [2.104s]
Computing hash join...  [5.121s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [83.357s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.694s]
Building query seed array...  [2.365s]
Computing hash join...  [5.091s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [54.529s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.462s]
Building query seed array...  [2.609s]
Computing hash join...  [5.015s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [44.667s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.927s]
Building query seed array...  [2.037s]
Computing hash join...  [5.073s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [41.513s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.079s]
Building query seed array...  [1.863s]
Computing hash join...  [5.031s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [40.21s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.224s]
Building query seed array...  [2.171s]
Computing hash join...  [4.866s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [33.036s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.079s]
Building query seed array...  [2.246s]
Computing hash join...  [4.824s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [36.462s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.03s]
Building query seed array...  [1.93s]
Computing hash join...  [4.866s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [31.521s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.122s]
Clearing query masking...  [1.569s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.368s]
Sorting trace points...  [1.278s]
Computing alignments...  [31.7s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.186s]
Computing alignments...  [32.083s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.225s]
Computing alignments...  [31.806s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.98s]
Sorting trace points...  [1.206s]
Computing alignments...  [33.096s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.256s]
Computing alignments...  [33.322s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.274s]
Computing alignments...  [33.571s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.094s]
Sorting trace points...  [1.272s]
Computing alignments...  [32.706s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.051s]
Sorting trace points...  [0.943s]
Computing alignments...  [32.659s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.211s]
Computing alignments...  [32.619s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.208s]
Computing alignments...  [32.456s]
Deallocating buffers...  [0.018s]
Loading trace points...  [1.365s]
Sorting trace points...  [1.271s]
Computing alignments...  [32.799s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.021s]
Computing alignments...  [32.761s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.088s]
Computing alignments...  [32.685s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.04s]
Sorting trace points...  [1.122s]
Computing alignments...  [32.92s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.241s]
Computing alignments...  [32.892s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [0.976s]
Computing alignments...  [32.455s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [551.204s]
Deallocating reference...  [0.063s]
Loading reference sequences...  [23.936s]
Masking reference...  [24.979s]
Initializing dictionary...  [0.062s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [26.166s]
Allocating buffers...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.484s]
Building query seed array...  [2.084s]
Computing hash join...  [4.255s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [63.536s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [10.386s]
Building query seed array...  [2.364s]
Computing hash join...  [4.271s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [42.853s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [10.778s]
Building query seed array...  [2.516s]
Computing hash join...  [4.233s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [35.472s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [8.467s]
Building query seed array...  [2.176s]
Computing hash join...  [4.288s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [32.976s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [8.18s]
Building query seed array...  [1.9s]
Computing hash join...  [4.045s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [33s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [10.003s]
Building query seed array...  [2.272s]
Computing hash join...  [4.04s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [26.997s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [10.52s]
Building query seed array...  [2.273s]
Computing hash join...  [4.05s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [29.206s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [8.293s]
Building query seed array...  [1.871s]
Computing hash join...  [4.083s]
Masking low complexity seeds...  [0.2s]
Searching alignments...  [24.712s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.118s]
Clearing query masking...  [1.608s]
Opening temporary output file...  [0.019s]
Computing alignments... Loading trace points...  [10.845s]
Sorting trace points...  [2.071s]
Computing alignments...  [50.68s]
Deallocating buffers...  [0.032s]
Loading trace points...  [0.149s]
Sorting trace points...  [1.802s]
Computing alignments...  [51.523s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0.141s]
Sorting trace points...  [2.079s]
Computing alignments...  [52.962s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.132s]
Sorting trace points...  [1.684s]
Computing alignments...  [51.92s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0.152s]
Sorting trace points...  [2.034s]
Computing alignments...  [51.715s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.111s]
Sorting trace points...  [1.699s]
Computing alignments...  [51.808s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.114s]
Sorting trace points...  [1.77s]
Computing alignments...  [52.026s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
Sorting trace points...  [2.003s]
Computing alignments...  [51.593s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0s]
 [441.283s]
Deallocating reference...  [0.05s]
Loading reference sequences...  [0.119s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [1933.01s]
 [1933.01s]
Deallocating queries...  [0.065s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [3.663s]
 [4.847s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 17969.3s
Reported 2451900966 pairwise alignments, 2451900966 HSPs.
13026695 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C20_R1.fastp-trim.20230215.fq.gz complete: C20_R1.blastx.meganized.daa

Now MEGANizing C20_R1.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: C20_R1.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 100% (235.4s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.2s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (4,558.5s)
Total reads:       13,026,695
With hits:          13,026,695 
Alignments:      2,434,967,629
Assig. Taxonomy:    11,973,012
Assig. SEED:           105,122
Assig. EGGNOG:          46,248
Assig. GTDB:           374,105
Assig. EC:           2,074,115
Assig. INTERPRO2GO:  1,165,880
MinSupport set to: 6513
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.3s)
Min-supp. changes:       4,045
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (11.8s)
Min-supp. changes:       2,960
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (38.6s)
Binning reads Syncing
100% (0.4s)
Class. Taxonomy:            73
Class. SEED:               493
Class. EGGNOG:           1,735
Class. GTDB:                17
Class. EC:               2,320
Class. INTERPRO2GO:      7,994
Total time:  4,854s
Peak memory: 29.3 of 195.3G
MEGANization of C20_R1.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C20_R2.fastp-trim.20230215.fq.gz...
21598d567e28774bc6f1afc5ca67de76  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C20_R2.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C20_R2.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.317s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.74s]
Opening the output file...  [0s]
Loading query sequences...  [74.416s]
Masking queries...  [18.736s]
Algorithm: Double-indexed
Building query histograms...  [22.468s]
Loading reference sequences...  [31.992s]
Masking reference...  [31.957s]
Initializing dictionary...  [0.08s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.271s]
Allocating buffers...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.128s]
Building query seed array...  [2.068s]
Computing hash join...  [5.412s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [80.483s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.245s]
Building query seed array...  [2.352s]
Computing hash join...  [5.191s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [52.963s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.626s]
Building query seed array...  [2.515s]
Computing hash join...  [5.203s]
Masking low complexity seeds...  [0.266s]
Searching alignments...  [43.858s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.004s]
Building query seed array...  [2.03s]
Computing hash join...  [5.361s]
Masking low complexity seeds...  [0.269s]
Searching alignments...  [39.639s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.983s]
Building query seed array...  [1.87s]
Computing hash join...  [5.068s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [44.922s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.692s]
Building query seed array...  [2.217s]
Computing hash join...  [5.009s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [32.92s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.176s]
Building query seed array...  [2.281s]
Computing hash join...  [5.049s]
Masking low complexity seeds...  [0.259s]
Searching alignments...  [37.075s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.065s]
Building query seed array...  [1.892s]
Computing hash join...  [5.008s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [31.577s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.592s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.402s]
Sorting trace points...  [1.233s]
Computing alignments...  [31.915s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.212s]
Computing alignments...  [32.044s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.09s]
Sorting trace points...  [1.17s]
Computing alignments...  [31.882s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.278s]
Computing alignments...  [33.034s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.096s]
Sorting trace points...  [1.273s]
Computing alignments...  [33.694s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.098s]
Sorting trace points...  [1.333s]
Computing alignments...  [33.613s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.72s]
Sorting trace points...  [1.285s]
Computing alignments...  [32.952s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.057s]
Sorting trace points...  [0.922s]
Computing alignments...  [32.687s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.285s]
Computing alignments...  [32.988s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.282s]
Computing alignments...  [33.575s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.042s]
Sorting trace points...  [1.29s]
Computing alignments...  [33.56s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.259s]
Computing alignments...  [33.766s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.294s]
Computing alignments...  [33.672s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.346s]
Computing alignments...  [33.895s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.276s]
Computing alignments...  [33.859s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.239s]
Computing alignments...  [33.388s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
 [558.923s]
Deallocating reference...  [0.073s]
Loading reference sequences...  [29.821s]
Masking reference...  [30.915s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.672s]
Allocating buffers...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.202s]
Building query seed array...  [2.137s]
Computing hash join...  [5.23s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [78.045s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.082s]
Building query seed array...  [2.405s]
Computing hash join...  [5.287s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [53.554s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.437s]
Building query seed array...  [2.537s]
Computing hash join...  [5.203s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [45.673s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.357s]
Building query seed array...  [2.006s]
Computing hash join...  [5.237s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [41.11s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.905s]
Building query seed array...  [1.878s]
Computing hash join...  [4.988s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [44.456s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.679s]
Building query seed array...  [2.167s]
Computing hash join...  [5.056s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [32.36s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.309s]
Building query seed array...  [2.388s]
Computing hash join...  [5.016s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [35.82s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.796s]
Building query seed array...  [1.822s]
Computing hash join...  [5.027s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [30.603s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.607s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.376s]
Sorting trace points...  [1.267s]
Computing alignments...  [31.668s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.195s]
Computing alignments...  [31.871s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.032s]
Computing alignments...  [31.605s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.24s]
Computing alignments...  [32.724s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.24s]
Computing alignments...  [33.885s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.153s]
Computing alignments...  [33.567s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.091s]
Sorting trace points...  [1.268s]
Computing alignments...  [33.236s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.423s]
Sorting trace points...  [1.251s]
Computing alignments...  [32.804s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.084s]
Sorting trace points...  [0.959s]
Computing alignments...  [33.239s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.29s]
Computing alignments...  [33.38s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.104s]
Sorting trace points...  [1.35s]
Computing alignments...  [33.513s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.083s]
Sorting trace points...  [0.972s]
Computing alignments...  [33.73s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.013s]
Computing alignments...  [33.566s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.04s]
Sorting trace points...  [1.223s]
Computing alignments...  [33.617s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.293s]
Computing alignments...  [33.904s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [1.091s]
Computing alignments...  [33.334s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [556.656s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [30.397s]
Masking reference...  [30.913s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.886s]
Allocating buffers...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.324s]
Building query seed array...  [2.057s]
Computing hash join...  [5.255s]
Masking low complexity seeds...  [0.268s]
Searching alignments...  [81.182s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.442s]
Building query seed array...  [2.392s]
Computing hash join...  [5.239s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [54.521s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.658s]
Building query seed array...  [2.579s]
Computing hash join...  [5.165s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [44.204s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.189s]
Building query seed array...  [2.014s]
Computing hash join...  [5.249s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [39.757s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.905s]
Building query seed array...  [1.832s]
Computing hash join...  [5.006s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [44.696s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.762s]
Building query seed array...  [2.204s]
Computing hash join...  [5.055s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [32.903s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.098s]
Building query seed array...  [2.302s]
Computing hash join...  [4.961s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [38.483s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.531s]
Building query seed array...  [1.87s]
Computing hash join...  [5.096s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [31.216s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.587s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.366s]
Sorting trace points...  [1.221s]
Computing alignments...  [31.901s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.23s]
Computing alignments...  [31.889s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.098s]
Sorting trace points...  [1.259s]
Computing alignments...  [31.621s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.066s]
Computing alignments...  [32.799s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.262s]
Computing alignments...  [33.813s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.267s]
Computing alignments...  [33.383s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.679s]
Sorting trace points...  [1.279s]
Computing alignments...  [33.011s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.086s]
Computing alignments...  [32.605s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.088s]
Sorting trace points...  [1.259s]
Computing alignments...  [33.11s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.064s]
Computing alignments...  [33.368s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.197s]
Computing alignments...  [33.356s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.381s]
Computing alignments...  [33.566s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.378s]
Computing alignments...  [33.362s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.313s]
Sorting trace points...  [1.308s]
Computing alignments...  [33.583s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.3s]
Computing alignments...  [33.773s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.163s]
Computing alignments...  [33.115s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
 [556.568s]
Deallocating reference...  [0.069s]
Loading reference sequences...  [33.252s]
Masking reference...  [31.447s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.681s]
Allocating buffers...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.223s]
Building query seed array...  [2.097s]
Computing hash join...  [5.267s]
Masking low complexity seeds...  [0.265s]
Searching alignments...  [78.693s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.618s]
Building query seed array...  [2.464s]
Computing hash join...  [5.21s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [53.643s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.349s]
Building query seed array...  [2.602s]
Computing hash join...  [5.228s]
Masking low complexity seeds...  [0.271s]
Searching alignments...  [45.389s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.947s]
Building query seed array...  [2.044s]
Computing hash join...  [5.23s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [40.021s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.868s]
Building query seed array...  [1.87s]
Computing hash join...  [4.991s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [43.467s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.446s]
Building query seed array...  [2.121s]
Computing hash join...  [5.002s]
Masking low complexity seeds...  [0.249s]
Searching alignments...  [32.617s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.501s]
Building query seed array...  [2.292s]
Computing hash join...  [4.94s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [36.252s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.073s]
Building query seed array...  [1.935s]
Computing hash join...  [5.072s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [29.984s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.129s]
Clearing query masking...  [1.611s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.496s]
Sorting trace points...  [1.247s]
Computing alignments...  [31.606s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.236s]
Computing alignments...  [31.738s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.205s]
Computing alignments...  [31.636s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.23s]
Computing alignments...  [32.738s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.23s]
Computing alignments...  [33.48s]
Deallocating buffers...  [0.032s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.309s]
Computing alignments...  [33.322s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.212s]
Computing alignments...  [32.756s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.264s]
Sorting trace points...  [1.295s]
Computing alignments...  [32.479s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.057s]
Computing alignments...  [32.923s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.095s]
Sorting trace points...  [1.101s]
Computing alignments...  [33.423s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.256s]
Computing alignments...  [33.408s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.089s]
Sorting trace points...  [1.321s]
Computing alignments...  [33.573s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.311s]
Computing alignments...  [33.494s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.051s]
Sorting trace points...  [0.983s]
Computing alignments...  [33.696s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.066s]
Computing alignments...  [33.712s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.273s]
Computing alignments...  [33.224s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0s]
 [554.584s]
Deallocating reference...  [0.066s]
Loading reference sequences...  [29.602s]
Masking reference...  [30.853s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.33s]
Allocating buffers...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.205s]
Building query seed array...  [2.061s]
Computing hash join...  [5.197s]
Masking low complexity seeds...  [0.268s]
Searching alignments...  [78.047s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.351s]
Building query seed array...  [2.422s]
Computing hash join...  [5.249s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [53.517s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.863s]
Building query seed array...  [2.569s]
Computing hash join...  [5.165s]
Masking low complexity seeds...  [0.259s]
Searching alignments...  [45.376s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.045s]
Building query seed array...  [2.055s]
Computing hash join...  [5.377s]
Masking low complexity seeds...  [0.27s]
Searching alignments...  [39.522s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.852s]
Building query seed array...  [1.831s]
Computing hash join...  [5.042s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [44.068s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.16s]
Building query seed array...  [2.167s]
Computing hash join...  [5.096s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [32.661s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.99s]
Building query seed array...  [2.259s]
Computing hash join...  [4.956s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [35.904s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.853s]
Building query seed array...  [1.894s]
Computing hash join...  [4.968s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [30.686s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.595s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.357s]
Sorting trace points...  [1.256s]
Computing alignments...  [31.557s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.159s]
Computing alignments...  [31.733s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.203s]
Computing alignments...  [31.737s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.235s]
Computing alignments...  [32.769s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.088s]
Sorting trace points...  [1.252s]
Computing alignments...  [33.469s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.068s]
Sorting trace points...  [0.993s]
Computing alignments...  [33.416s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.094s]
Sorting trace points...  [1.251s]
Computing alignments...  [32.765s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.209s]
Computing alignments...  [32.492s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.089s]
Sorting trace points...  [1.281s]
Computing alignments...  [32.884s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.111s]
Sorting trace points...  [0.989s]
Computing alignments...  [33.414s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.318s]
Computing alignments...  [33.383s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.337s]
Computing alignments...  [33.579s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.305s]
Computing alignments...  [33.539s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.344s]
Computing alignments...  [33.608s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.313s]
Computing alignments...  [33.647s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [0.998s]
Computing alignments...  [33.177s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
 [554.419s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.526s]
Masking reference...  [30.832s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.707s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.245s]
Building query seed array...  [2.072s]
Computing hash join...  [5.274s]
Masking low complexity seeds...  [0.265s]
Searching alignments...  [75.532s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.499s]
Building query seed array...  [2.41s]
Computing hash join...  [5.316s]
Masking low complexity seeds...  [0.268s]
Searching alignments...  [51.574s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.597s]
Building query seed array...  [2.579s]
Computing hash join...  [5.182s]
Masking low complexity seeds...  [0.274s]
Searching alignments...  [43.272s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.027s]
Building query seed array...  [2.024s]
Computing hash join...  [5.247s]
Masking low complexity seeds...  [0.268s]
Searching alignments...  [38.712s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.156s]
Building query seed array...  [1.918s]
Computing hash join...  [5.037s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [40.911s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.906s]
Building query seed array...  [2.162s]
Computing hash join...  [4.978s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [32.498s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.388s]
Building query seed array...  [2.34s]
Computing hash join...  [4.997s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [34.871s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.19s]
Building query seed array...  [1.897s]
Computing hash join...  [5.061s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [30.254s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.128s]
Clearing query masking...  [1.558s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.314s]
Sorting trace points...  [1.253s]
Computing alignments...  [31.157s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.04s]
Sorting trace points...  [1.173s]
Computing alignments...  [31.386s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.071s]
Sorting trace points...  [0.934s]
Computing alignments...  [31.23s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.249s]
Computing alignments...  [32.252s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.228s]
Computing alignments...  [32.661s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.058s]
Sorting trace points...  [0.949s]
Computing alignments...  [32.804s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.282s]
Computing alignments...  [32.142s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.107s]
Computing alignments...  [32.002s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.226s]
Computing alignments...  [32.396s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.274s]
Computing alignments...  [33.073s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.298s]
Computing alignments...  [33.005s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.299s]
Computing alignments...  [33.221s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.073s]
Sorting trace points...  [0.971s]
Computing alignments...  [33.183s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.06s]
Computing alignments...  [33.297s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.307s]
Computing alignments...  [33.365s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.232s]
Computing alignments...  [32.8s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
 [546.383s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [31.585s]
Masking reference...  [31.08s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.723s]
Allocating buffers...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.19s]
Building query seed array...  [2.094s]
Computing hash join...  [5.268s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [80.421s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.523s]
Building query seed array...  [2.405s]
Computing hash join...  [5.178s]
Masking low complexity seeds...  [0.27s]
Searching alignments...  [52.648s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.55s]
Building query seed array...  [2.563s]
Computing hash join...  [5.232s]
Masking low complexity seeds...  [0.268s]
Searching alignments...  [45.66s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.999s]
Building query seed array...  [2.064s]
Computing hash join...  [5.177s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [39.184s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.847s]
Building query seed array...  [1.902s]
Computing hash join...  [5.004s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [44.451s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.277s]
Building query seed array...  [2.177s]
Computing hash join...  [5.002s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [32.666s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.213s]
Building query seed array...  [2.251s]
Computing hash join...  [4.955s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [37.279s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.904s]
Building query seed array...  [1.857s]
Computing hash join...  [5.106s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [30.369s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.121s]
Clearing query masking...  [1.535s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.438s]
Sorting trace points...  [1.265s]
Computing alignments...  [31.664s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.079s]
Computing alignments...  [31.753s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.186s]
Sorting trace points...  [1.057s]
Computing alignments...  [31.54s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.197s]
Computing alignments...  [32.709s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.088s]
Sorting trace points...  [1.038s]
Computing alignments...  [33.232s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.068s]
Sorting trace points...  [0.95s]
Computing alignments...  [33.28s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.022s]
Computing alignments...  [32.881s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.149s]
Computing alignments...  [32.522s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.313s]
Computing alignments...  [32.897s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.258s]
Computing alignments...  [33.394s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.085s]
Sorting trace points...  [1.06s]
Computing alignments...  [33.308s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.311s]
Computing alignments...  [33.546s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.285s]
Computing alignments...  [33.458s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.304s]
Computing alignments...  [33.601s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.28s]
Computing alignments...  [33.815s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.271s]
Computing alignments...  [33.175s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [553.583s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [35.718s]
Masking reference...  [31.02s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.781s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.552s]
Building query seed array...  [2.099s]
Computing hash join...  [5.254s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [77.234s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.562s]
Building query seed array...  [2.494s]
Computing hash join...  [5.194s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [53.568s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.252s]
Building query seed array...  [2.563s]
Computing hash join...  [5.112s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [45.029s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.917s]
Building query seed array...  [2.014s]
Computing hash join...  [5.201s]
Masking low complexity seeds...  [0.267s]
Searching alignments...  [40.921s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.32s]
Building query seed array...  [1.826s]
Computing hash join...  [4.988s]
Masking low complexity seeds...  [0.249s]
Searching alignments...  [44.324s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.246s]
Building query seed array...  [2.165s]
Computing hash join...  [5.053s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [33.55s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.117s]
Building query seed array...  [2.291s]
Computing hash join...  [4.972s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [36.318s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.716s]
Building query seed array...  [1.902s]
Computing hash join...  [5.005s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [30.187s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.141s]
Clearing query masking...  [1.621s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.403s]
Sorting trace points...  [1.286s]
Computing alignments...  [31.686s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.054s]
Computing alignments...  [31.801s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.23s]
Computing alignments...  [31.642s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.847s]
Sorting trace points...  [1.28s]
Computing alignments...  [32.675s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.098s]
Computing alignments...  [33.235s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.185s]
Computing alignments...  [33.328s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.271s]
Computing alignments...  [32.774s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.057s]
Sorting trace points...  [0.93s]
Computing alignments...  [32.496s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.087s]
Sorting trace points...  [1.032s]
Computing alignments...  [32.902s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.037s]
Computing alignments...  [33.397s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.776s]
Sorting trace points...  [1.34s]
Computing alignments...  [33.361s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.082s]
Computing alignments...  [33.515s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.218s]
Computing alignments...  [33.588s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.268s]
Computing alignments...  [33.631s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.116s]
Computing alignments...  [33.703s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.269s]
Computing alignments...  [33.154s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [554.818s]
Deallocating reference...  [0.063s]
Loading reference sequences...  [29.728s]
Masking reference...  [32.21s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.006s]
Building reference histograms...  [31.823s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.68s]
Building query seed array...  [2.07s]
Computing hash join...  [5.291s]
Masking low complexity seeds...  [0.272s]
Searching alignments...  [80.476s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.722s]
Building query seed array...  [2.355s]
Computing hash join...  [5.257s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [51.544s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.512s]
Building query seed array...  [2.56s]
Computing hash join...  [5.175s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [44.286s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.835s]
Building query seed array...  [2.037s]
Computing hash join...  [5.171s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [39.148s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.953s]
Building query seed array...  [1.836s]
Computing hash join...  [4.968s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [43.805s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.521s]
Building query seed array...  [2.164s]
Computing hash join...  [5.114s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [32.468s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.176s]
Building query seed array...  [2.364s]
Computing hash join...  [4.913s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [37.681s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.669s]
Building query seed array...  [1.851s]
Computing hash join...  [4.986s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [30.426s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.122s]
Clearing query masking...  [1.608s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.408s]
Sorting trace points...  [1.275s]
Computing alignments...  [31.57s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.243s]
Computing alignments...  [31.617s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.211s]
Computing alignments...  [31.467s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.21s]
Computing alignments...  [32.683s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.292s]
Computing alignments...  [33.373s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.272s]
Computing alignments...  [33.343s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.079s]
Sorting trace points...  [0.983s]
Computing alignments...  [32.798s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.275s]
Computing alignments...  [32.396s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.071s]
Computing alignments...  [32.864s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.104s]
Sorting trace points...  [1.102s]
Computing alignments...  [33.341s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.301s]
Computing alignments...  [33.269s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.343s]
Computing alignments...  [33.474s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.236s]
Computing alignments...  [33.409s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.042s]
Sorting trace points...  [1.081s]
Computing alignments...  [33.525s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.273s]
Computing alignments...  [33.603s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.246s]
Computing alignments...  [33.096s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [552.985s]
Deallocating reference...  [0.063s]
Loading reference sequences...  [29.578s]
Masking reference...  [32.114s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.364s]
Allocating buffers...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.155s]
Building query seed array...  [2.126s]
Computing hash join...  [5.306s]
Masking low complexity seeds...  [0.268s]
Searching alignments...  [81.04s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.486s]
Building query seed array...  [2.477s]
Computing hash join...  [5.162s]
Masking low complexity seeds...  [0.259s]
Searching alignments...  [53.934s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.864s]
Building query seed array...  [2.49s]
Computing hash join...  [5.133s]
Masking low complexity seeds...  [0.265s]
Searching alignments...  [46.24s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.878s]
Building query seed array...  [2.04s]
Computing hash join...  [5.196s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [41.012s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.101s]
Building query seed array...  [1.862s]
Computing hash join...  [5.017s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [43.867s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.453s]
Building query seed array...  [2.183s]
Computing hash join...  [5.019s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [33.527s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.301s]
Building query seed array...  [2.238s]
Computing hash join...  [5.035s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [36.826s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.134s]
Building query seed array...  [1.831s]
Computing hash join...  [4.915s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [30.756s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.128s]
Clearing query masking...  [1.52s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.556s]
Sorting trace points...  [1.217s]
Computing alignments...  [31.598s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.026s]
Computing alignments...  [31.739s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.104s]
Computing alignments...  [31.665s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.226s]
Computing alignments...  [32.731s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.228s]
Computing alignments...  [33.244s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.007s]
Computing alignments...  [33.301s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.093s]
Sorting trace points...  [1.259s]
Computing alignments...  [32.642s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.266s]
Computing alignments...  [32.443s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.26s]
Computing alignments...  [32.879s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.091s]
Sorting trace points...  [1.325s]
Computing alignments...  [33.436s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.065s]
Computing alignments...  [33.353s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.268s]
Computing alignments...  [33.647s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.218s]
Computing alignments...  [33.538s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.291s]
Computing alignments...  [33.625s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.085s]
Sorting trace points...  [1.288s]
Computing alignments...  [33.647s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.251s]
Computing alignments...  [33.134s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
 [553.874s]
Deallocating reference...  [0.069s]
Loading reference sequences...  [29.637s]
Masking reference...  [30.852s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.006s]
Building reference histograms...  [32.763s]
Allocating buffers...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.148s]
Building query seed array...  [2.078s]
Computing hash join...  [5.274s]
Masking low complexity seeds...  [0.267s]
Searching alignments...  [76.992s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.633s]
Building query seed array...  [2.432s]
Computing hash join...  [5.216s]
Masking low complexity seeds...  [0.269s]
Searching alignments...  [53.105s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.802s]
Building query seed array...  [2.598s]
Computing hash join...  [5.143s]
Masking low complexity seeds...  [0.274s]
Searching alignments...  [44.25s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.414s]
Building query seed array...  [2.057s]
Computing hash join...  [5.153s]
Masking low complexity seeds...  [0.274s]
Searching alignments...  [38.591s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.405s]
Building query seed array...  [1.882s]
Computing hash join...  [4.949s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [42.296s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.169s]
Building query seed array...  [2.188s]
Computing hash join...  [5.004s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [32.566s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.949s]
Building query seed array...  [2.411s]
Computing hash join...  [4.985s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [36.505s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.857s]
Building query seed array...  [1.925s]
Computing hash join...  [4.919s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [30.061s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.536s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.287s]
Sorting trace points...  [1.253s]
Computing alignments...  [31.582s]
Deallocating buffers...  [0.015s]
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Sorting trace points...  [1.058s]
Computing alignments...  [31.849s]
Deallocating buffers...  [0.022s]
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Sorting trace points...  [1.209s]
Computing alignments...  [31.703s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.066s]
Computing alignments...  [32.841s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.064s]
Computing alignments...  [33.834s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.28s]
Computing alignments...  [33.473s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.106s]
Sorting trace points...  [1.217s]
Computing alignments...  [33.203s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.269s]
Computing alignments...  [32.811s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.891s]
Sorting trace points...  [1.326s]
Computing alignments...  [33.265s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.431s]
Sorting trace points...  [1.152s]
Computing alignments...  [33.622s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.014s]
Computing alignments...  [33.284s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.009s]
Computing alignments...  [33.966s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.252s]
Computing alignments...  [33.532s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.34s]
Computing alignments...  [33.553s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.078s]
Computing alignments...  [33.804s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.223s]
Computing alignments...  [33.141s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
 [556.958s]
Deallocating reference...  [0.063s]
Loading reference sequences...  [29.794s]
Masking reference...  [30.864s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.006s]
Building reference histograms...  [32.416s]
Allocating buffers...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.105s]
Building query seed array...  [2.025s]
Computing hash join...  [5.286s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [79.278s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.448s]
Building query seed array...  [2.471s]
Computing hash join...  [5.23s]
Masking low complexity seeds...  [0.274s]
Searching alignments...  [52.695s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [12.822s]
Building query seed array...  [2.58s]
Computing hash join...  [5.175s]
Masking low complexity seeds...  [0.265s]
Searching alignments...  [44.646s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.086s]
Building query seed array...  [2.043s]
Computing hash join...  [5.131s]
Masking low complexity seeds...  [0.265s]
Searching alignments...  [39.137s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.235s]
Building query seed array...  [1.894s]
Computing hash join...  [5.025s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [44.124s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.672s]
Building query seed array...  [2.169s]
Computing hash join...  [5.056s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [32.568s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.172s]
Building query seed array...  [2.258s]
Computing hash join...  [5.008s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [36.46s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.828s]
Building query seed array...  [1.93s]
Computing hash join...  [5.054s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [30.186s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.525s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.367s]
Sorting trace points...  [1.261s]
Computing alignments...  [31.624s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.207s]
Computing alignments...  [31.55s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.202s]
Computing alignments...  [31.506s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.265s]
Computing alignments...  [32.416s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.281s]
Computing alignments...  [33.087s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.249s]
Computing alignments...  [33.08s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.272s]
Computing alignments...  [32.588s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.063s]
Sorting trace points...  [0.933s]
Computing alignments...  [32.264s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.227s]
Computing alignments...  [32.834s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.304s]
Computing alignments...  [33.377s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.151s]
Computing alignments...  [33.336s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.307s]
Computing alignments...  [33.474s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.247s]
Computing alignments...  [33.391s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.311s]
Computing alignments...  [33.535s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.085s]
Computing alignments...  [33.696s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.279s]
Computing alignments...  [33.113s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [552.105s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.569s]
Masking reference...  [30.866s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.006s]
Building reference histograms...  [32.723s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.186s]
Building query seed array...  [2.057s]
Computing hash join...  [5.201s]
Masking low complexity seeds...  [0.271s]
Searching alignments...  [79.448s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.692s]
Building query seed array...  [2.374s]
Computing hash join...  [5.232s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [51.682s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.07s]
Building query seed array...  [2.652s]
Computing hash join...  [5.203s]
Masking low complexity seeds...  [0.265s]
Searching alignments...  [44.955s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.965s]
Building query seed array...  [2.084s]
Computing hash join...  [5.194s]
Masking low complexity seeds...  [0.269s]
Searching alignments...  [40.576s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.839s]
Building query seed array...  [1.896s]
Computing hash join...  [4.988s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [44.416s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.827s]
Building query seed array...  [2.189s]
Computing hash join...  [4.933s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [33.533s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.037s]
Building query seed array...  [2.334s]
Computing hash join...  [4.972s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [36.875s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.782s]
Building query seed array...  [1.947s]
Computing hash join...  [5.037s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [30.375s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.128s]
Clearing query masking...  [1.523s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.231s]
Sorting trace points...  [1.31s]
Computing alignments...  [31.713s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.261s]
Computing alignments...  [31.759s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.062s]
Sorting trace points...  [0.906s]
Computing alignments...  [31.532s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.108s]
Computing alignments...  [32.701s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.25s]
Computing alignments...  [33.613s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.288s]
Computing alignments...  [33.274s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.069s]
Sorting trace points...  [0.956s]
Computing alignments...  [32.929s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.195s]
Computing alignments...  [32.531s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.271s]
Computing alignments...  [33.026s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.291s]
Computing alignments...  [33.297s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.305s]
Computing alignments...  [33.335s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.093s]
Sorting trace points...  [1.286s]
Computing alignments...  [33.625s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.457s]
Sorting trace points...  [1.303s]
Computing alignments...  [33.503s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.281s]
Computing alignments...  [33.521s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.229s]
Computing alignments...  [33.709s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.268s]
Computing alignments...  [33.088s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [554.683s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [23.825s]
Masking reference...  [26.021s]
Initializing dictionary...  [0.063s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [25.81s]
Allocating buffers...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.674s]
Building query seed array...  [2.049s]
Computing hash join...  [4.288s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [63.942s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [9.908s]
Building query seed array...  [2.382s]
Computing hash join...  [4.344s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [41.944s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [10.814s]
Building query seed array...  [2.623s]
Computing hash join...  [4.286s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [35.564s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [7.955s]
Building query seed array...  [1.985s]
Computing hash join...  [4.387s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [32.304s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [8.256s]
Building query seed array...  [1.851s]
Computing hash join...  [4.148s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [36.02s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [9.682s]
Building query seed array...  [2.155s]
Computing hash join...  [4.168s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [27.937s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [10.523s]
Building query seed array...  [2.264s]
Computing hash join...  [4.167s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [29.199s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [8.2s]
Building query seed array...  [1.884s]
Computing hash join...  [4.171s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [24.513s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.106s]
Clearing query masking...  [1.62s]
Opening temporary output file...  [0.033s]
Computing alignments... Loading trace points...  [10.667s]
Sorting trace points...  [2.036s]
Computing alignments...  [50.286s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.157s]
Sorting trace points...  [1.935s]
Computing alignments...  [51.07s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.151s]
Sorting trace points...  [2.065s]
Computing alignments...  [52.781s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.118s]
Sorting trace points...  [1.984s]
Computing alignments...  [51.637s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.13s]
Sorting trace points...  [2.145s]
Computing alignments...  [52.536s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.163s]
Sorting trace points...  [1.677s]
Computing alignments...  [53.163s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.176s]
Sorting trace points...  [1.62s]
Computing alignments...  [53.354s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0s]
Sorting trace points...  [2.105s]
Computing alignments...  [52.775s]
Deallocating buffers...  [0.036s]
Loading trace points...  [0s]
 [445.065s]
Deallocating reference...  [0.053s]
Loading reference sequences...  [0.077s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [1922.95s]
 [1922.95s]
Deallocating queries...  [0.05s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [3.685s]
 [4.807s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 18112.1s
Reported 2392185082 pairwise alignments, 2392185082 HSPs.
13376766 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C20_R2.fastp-trim.20230215.fq.gz complete: C20_R2.blastx.meganized.daa

Now MEGANizing C20_R2.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: C20_R2.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 100% (243.9s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.2s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (4,421.2s)
Total reads:       13,376,766
With hits:          13,376,766 
Alignments:      2,377,750,554
Assig. Taxonomy:    12,260,964
Assig. SEED:           102,988
Assig. EGGNOG:          45,186
Assig. GTDB:           364,465
Assig. EC:           2,118,036
Assig. INTERPRO2GO:  1,165,881
MinSupport set to: 6688
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.4s)
Min-supp. changes:       4,111
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (11.6s)
Min-supp. changes:       3,114
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (31.8s)
Binning reads Syncing
100% (0.3s)
Class. Taxonomy:            74
Class. SEED:               491
Class. EGGNOG:           1,732
Class. GTDB:                15
Class. EC:               2,322
Class. INTERPRO2GO:      8,079
Total time:  4,719s
Peak memory: 30.6 of 195.3G
MEGANization of C20_R2.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C21_R1.fastp-trim.20230215.fq.gz...
2de10819d2775f678b492a8bee6a3d94  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C21_R1.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C21_R1.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.303s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.715s]
Opening the output file...  [0s]
Loading query sequences...  [53.767s]
Masking queries...  [13.01s]
Algorithm: Double-indexed
Building query histograms...  [13.852s]
Loading reference sequences...  [29.455s]
Masking reference...  [32.089s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.007s]
Allocating buffers...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.435s]
Building query seed array...  [1.45s]
Computing hash join...  [4.94s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [52.607s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.639s]
Building query seed array...  [1.729s]
Computing hash join...  [4.871s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [33.359s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.707s]
Building query seed array...  [1.813s]
Computing hash join...  [4.94s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [30.74s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.406s]
Building query seed array...  [1.44s]
Computing hash join...  [4.974s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [26.768s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.78s]
Building query seed array...  [1.362s]
Computing hash join...  [4.684s]
Masking low complexity seeds...  [0.197s]
Searching alignments...  [28.205s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.538s]
Building query seed array...  [1.55s]
Computing hash join...  [4.75s]
Masking low complexity seeds...  [0.19s]
Searching alignments...  [22.326s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.66s]
Building query seed array...  [1.633s]
Computing hash join...  [4.789s]
Masking low complexity seeds...  [0.197s]
Searching alignments...  [23.54s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.024s]
Building query seed array...  [1.418s]
Computing hash join...  [4.723s]
Masking low complexity seeds...  [0.192s]
Searching alignments...  [21.325s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.118s]
Clearing query masking...  [1.135s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [9.583s]
Sorting trace points...  [1.594s]
Computing alignments...  [43.3s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.122s]
Sorting trace points...  [1.495s]
Computing alignments...  [43.431s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.109s]
Sorting trace points...  [1.366s]
Computing alignments...  [42.658s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.105s]
Sorting trace points...  [1.658s]
Computing alignments...  [42.879s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.148s]
Sorting trace points...  [1.567s]
Computing alignments...  [44.769s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.084s]
Sorting trace points...  [1.744s]
Computing alignments...  [45.031s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.117s]
Sorting trace points...  [1.377s]
Computing alignments...  [45.085s]
Deallocating buffers...  [0.032s]
Loading trace points...  [0s]
Sorting trace points...  [1.471s]
Computing alignments...  [44.81s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [374.781s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.586s]
Masking reference...  [30.853s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.776s]
Allocating buffers...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.068s]
Building query seed array...  [1.49s]
Computing hash join...  [4.873s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [50.908s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [13.029s]
Building query seed array...  [1.78s]
Computing hash join...  [4.934s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [34.12s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.428s]
Building query seed array...  [1.867s]
Computing hash join...  [4.862s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [29.173s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.217s]
Building query seed array...  [1.443s]
Computing hash join...  [4.812s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [25.865s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.106s]
Building query seed array...  [1.403s]
Computing hash join...  [4.663s]
Masking low complexity seeds...  [0.192s]
Searching alignments...  [26.321s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.399s]
Building query seed array...  [1.593s]
Computing hash join...  [4.705s]
Masking low complexity seeds...  [0.191s]
Searching alignments...  [21.811s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.719s]
Building query seed array...  [1.618s]
Computing hash join...  [4.718s]
Masking low complexity seeds...  [0.194s]
Searching alignments...  [23.597s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.909s]
Building query seed array...  [1.353s]
Computing hash join...  [4.657s]
Masking low complexity seeds...  [0.198s]
Searching alignments...  [20.302s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.119s]
Clearing query masking...  [1.248s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [9.21s]
Sorting trace points...  [1.691s]
Computing alignments...  [43.011s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.618s]
Computing alignments...  [43.225s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.554s]
Sorting trace points...  [1.65s]
Computing alignments...  [42.455s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.106s]
Sorting trace points...  [1.403s]
Computing alignments...  [42.701s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.13s]
Sorting trace points...  [1.483s]
Computing alignments...  [44.528s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.181s]
Sorting trace points...  [1.703s]
Computing alignments...  [44.786s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.091s]
Sorting trace points...  [1.731s]
Computing alignments...  [45.051s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0s]
Sorting trace points...  [1.41s]
Computing alignments...  [44.72s]
Deallocating buffers...  [0.032s]
Loading trace points...  [0s]
 [373.807s]
Deallocating reference...  [0.076s]
Loading reference sequences...  [29.805s]
Masking reference...  [32.15s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.362s]
Allocating buffers...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.205s]
Building query seed array...  [1.477s]
Computing hash join...  [4.884s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [54.245s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.858s]
Building query seed array...  [1.713s]
Computing hash join...  [4.867s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [36.062s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.199s]
Building query seed array...  [1.801s]
Computing hash join...  [4.862s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [31.408s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.07s]
Building query seed array...  [1.473s]
Computing hash join...  [4.824s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [26.214s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.318s]
Building query seed array...  [1.353s]
Computing hash join...  [4.691s]
Masking low complexity seeds...  [0.197s]
Searching alignments...  [26.847s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.366s]
Building query seed array...  [1.595s]
Computing hash join...  [4.684s]
Masking low complexity seeds...  [0.188s]
Searching alignments...  [23.241s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.333s]
Building query seed array...  [1.657s]
Computing hash join...  [4.707s]
Masking low complexity seeds...  [0.191s]
Searching alignments...  [23.391s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.834s]
Building query seed array...  [1.315s]
Computing hash join...  [4.738s]
Masking low complexity seeds...  [0.196s]
Searching alignments...  [20.238s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.118s]
Clearing query masking...  [1.068s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [9.435s]
Sorting trace points...  [1.761s]
Computing alignments...  [43.236s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.13s]
Sorting trace points...  [1.68s]
Computing alignments...  [43.332s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.118s]
Sorting trace points...  [1.391s]
Computing alignments...  [42.615s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.111s]
Sorting trace points...  [1.419s]
Computing alignments...  [42.835s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.146s]
Sorting trace points...  [1.411s]
Computing alignments...  [44.57s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.427s]
Computing alignments...  [44.902s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.153s]
Sorting trace points...  [1.514s]
Computing alignments...  [45.056s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0s]
Sorting trace points...  [1.396s]
Computing alignments...  [44.729s]
Deallocating buffers...  [0.032s]
Loading trace points...  [0s]
 [373.776s]
Deallocating reference...  [0.073s]
Loading reference sequences...  [29.745s]
Masking reference...  [32.158s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.126s]
Allocating buffers...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.331s]
Building query seed array...  [1.524s]
Computing hash join...  [4.833s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [52.146s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.456s]
Building query seed array...  [1.79s]
Computing hash join...  [4.839s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [35.048s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.889s]
Building query seed array...  [1.808s]
Computing hash join...  [4.917s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [32.412s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.1s]
Building query seed array...  [1.514s]
Computing hash join...  [4.924s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [27.105s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.931s]
Building query seed array...  [1.365s]
Computing hash join...  [4.675s]
Masking low complexity seeds...  [0.195s]
Searching alignments...  [26.489s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.214s]
Building query seed array...  [1.547s]
Computing hash join...  [4.68s]
Masking low complexity seeds...  [0.187s]
Searching alignments...  [21.539s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.177s]
Building query seed array...  [1.657s]
Computing hash join...  [4.658s]
Masking low complexity seeds...  [0.197s]
Searching alignments...  [24.656s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.726s]
Building query seed array...  [1.334s]
Computing hash join...  [4.742s]
Masking low complexity seeds...  [0.191s]
Searching alignments...  [20.163s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.117s]
Clearing query masking...  [1.066s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [9.382s]
Sorting trace points...  [1.728s]
Computing alignments...  [43.442s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.129s]
Sorting trace points...  [1.709s]
Computing alignments...  [43.449s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.157s]
Sorting trace points...  [1.464s]
Computing alignments...  [42.54s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.183s]
Sorting trace points...  [1.686s]
Computing alignments...  [42.908s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.505s]
Sorting trace points...  [1.438s]
Computing alignments...  [44.606s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.662s]
Computing alignments...  [45.106s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.122s]
Sorting trace points...  [1.764s]
Computing alignments...  [45.189s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.549s]
Computing alignments...  [44.786s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0s]
 [375.903s]
Deallocating reference...  [0.077s]
Loading reference sequences...  [29.745s]
Masking reference...  [30.83s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.642s]
Allocating buffers...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.123s]
Building query seed array...  [1.504s]
Computing hash join...  [4.98s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [52.461s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.866s]
Building query seed array...  [1.711s]
Computing hash join...  [4.902s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [33.368s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.14s]
Building query seed array...  [1.821s]
Computing hash join...  [4.846s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [29.297s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.331s]
Building query seed array...  [1.531s]
Computing hash join...  [4.866s]
Masking low complexity seeds...  [0.199s]
Searching alignments...  [27.506s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.1s]
Building query seed array...  [1.354s]
Computing hash join...  [4.696s]
Masking low complexity seeds...  [0.191s]
Searching alignments...  [26.073s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.147s]
Building query seed array...  [1.583s]
Computing hash join...  [4.623s]
Masking low complexity seeds...  [0.188s]
Searching alignments...  [21.724s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.339s]
Building query seed array...  [1.614s]
Computing hash join...  [4.787s]
Masking low complexity seeds...  [0.197s]
Searching alignments...  [23.552s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.047s]
Building query seed array...  [1.339s]
Computing hash join...  [4.736s]
Masking low complexity seeds...  [0.196s]
Searching alignments...  [20.316s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.139s]
Clearing query masking...  [1.165s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [9.571s]
Sorting trace points...  [1.754s]
Computing alignments...  [42.877s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.125s]
Sorting trace points...  [1.412s]
Computing alignments...  [43.241s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.109s]
Sorting trace points...  [1.314s]
Computing alignments...  [42.472s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.127s]
Sorting trace points...  [1.615s]
Computing alignments...  [42.639s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.172s]
Sorting trace points...  [1.401s]
Computing alignments...  [44.506s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.148s]
Sorting trace points...  [1.728s]
Computing alignments...  [44.809s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.114s]
Sorting trace points...  [1.376s]
Computing alignments...  [44.851s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [1.703s]
Computing alignments...  [44.547s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0s]
 [373.006s]
Deallocating reference...  [0.073s]
Loading reference sequences...  [29.51s]
Masking reference...  [30.827s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.969s]
Allocating buffers...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.299s]
Building query seed array...  [1.537s]
Computing hash join...  [4.846s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [49.276s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.287s]
Building query seed array...  [1.755s]
Computing hash join...  [4.824s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [32.561s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.348s]
Building query seed array...  [1.871s]
Computing hash join...  [4.79s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [28.636s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.998s]
Building query seed array...  [1.453s]
Computing hash join...  [4.821s]
Masking low complexity seeds...  [0.2s]
Searching alignments...  [27.275s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.799s]
Building query seed array...  [1.313s]
Computing hash join...  [4.84s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [25.963s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.375s]
Building query seed array...  [1.538s]
Computing hash join...  [4.756s]
Masking low complexity seeds...  [0.194s]
Searching alignments...  [21.586s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.082s]
Building query seed array...  [1.638s]
Computing hash join...  [4.824s]
Masking low complexity seeds...  [0.196s]
Searching alignments...  [23.374s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.115s]
Building query seed array...  [1.329s]
Computing hash join...  [4.709s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [20.859s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.127s]
Clearing query masking...  [1.153s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [10.602s]
Sorting trace points...  [1.709s]
Computing alignments...  [43.06s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.621s]
Computing alignments...  [43.094s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.414s]
Computing alignments...  [42.332s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.111s]
Sorting trace points...  [1.366s]
Computing alignments...  [42.473s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.132s]
Sorting trace points...  [1.752s]
Computing alignments...  [44.364s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.157s]
Sorting trace points...  [1.664s]
Computing alignments...  [44.614s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.145s]
Sorting trace points...  [1.732s]
Computing alignments...  [44.791s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0s]
Sorting trace points...  [1.735s]
Computing alignments...  [44.406s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0s]
 [373.665s]
Deallocating reference...  [0.076s]
Loading reference sequences...  [29.622s]
Masking reference...  [30.837s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.653s]
Allocating buffers...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.079s]
Building query seed array...  [1.508s]
Computing hash join...  [4.784s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [50.44s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.405s]
Building query seed array...  [1.739s]
Computing hash join...  [4.811s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [33.805s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.068s]
Building query seed array...  [1.819s]
Computing hash join...  [4.789s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [29.518s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.303s]
Building query seed array...  [1.495s]
Computing hash join...  [4.923s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [27.276s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.156s]
Building query seed array...  [1.341s]
Computing hash join...  [4.763s]
Masking low complexity seeds...  [0.193s]
Searching alignments...  [26.536s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.904s]
Building query seed array...  [1.534s]
Computing hash join...  [4.635s]
Masking low complexity seeds...  [0.19s]
Searching alignments...  [21.523s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.306s]
Building query seed array...  [1.637s]
Computing hash join...  [4.734s]
Masking low complexity seeds...  [0.2s]
Searching alignments...  [23.815s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.191s]
Building query seed array...  [1.331s]
Computing hash join...  [4.671s]
Masking low complexity seeds...  [0.2s]
Searching alignments...  [21.123s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.119s]
Clearing query masking...  [1.086s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [9.526s]
Sorting trace points...  [1.673s]
Computing alignments...  [43.133s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.143s]
Sorting trace points...  [1.559s]
Computing alignments...  [43.424s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.111s]
Sorting trace points...  [1.64s]
Computing alignments...  [42.682s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.12s]
Sorting trace points...  [1.668s]
Computing alignments...  [42.771s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.17s]
Sorting trace points...  [1.371s]
Computing alignments...  [44.656s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.143s]
Sorting trace points...  [1.487s]
Computing alignments...  [44.784s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.109s]
Sorting trace points...  [1.828s]
Computing alignments...  [44.835s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
Sorting trace points...  [1.699s]
Computing alignments...  [44.532s]
Deallocating buffers...  [0.034s]
Loading trace points...  [0s]
 [374.621s]
Deallocating reference...  [0.074s]
Loading reference sequences...  [30.058s]
Masking reference...  [32.035s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.6s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.209s]
Building query seed array...  [1.509s]
Computing hash join...  [4.848s]
Masking low complexity seeds...  [0.199s]
Searching alignments...  [49.829s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.556s]
Building query seed array...  [1.747s]
Computing hash join...  [4.859s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [33.621s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.414s]
Building query seed array...  [1.832s]
Computing hash join...  [4.786s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [29.829s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.001s]
Building query seed array...  [1.439s]
Computing hash join...  [4.916s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [26.922s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.541s]
Building query seed array...  [1.329s]
Computing hash join...  [4.703s]
Masking low complexity seeds...  [0.193s]
Searching alignments...  [27.688s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.031s]
Building query seed array...  [1.565s]
Computing hash join...  [4.719s]
Masking low complexity seeds...  [0.196s]
Searching alignments...  [21.666s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.083s]
Building query seed array...  [1.598s]
Computing hash join...  [4.751s]
Masking low complexity seeds...  [0.193s]
Searching alignments...  [23.702s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.788s]
Building query seed array...  [1.314s]
Computing hash join...  [4.733s]
Masking low complexity seeds...  [0.198s]
Searching alignments...  [21.279s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.138s]
Clearing query masking...  [1.141s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [9.533s]
Sorting trace points...  [1.787s]
Computing alignments...  [43.056s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.167s]
Sorting trace points...  [1.379s]
Computing alignments...  [43.424s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.168s]
Sorting trace points...  [1.64s]
Computing alignments...  [42.6s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.134s]
Sorting trace points...  [1.585s]
Computing alignments...  [42.744s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.14s]
Sorting trace points...  [1.817s]
Computing alignments...  [44.668s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.44s]
Computing alignments...  [44.9s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.116s]
Sorting trace points...  [1.415s]
Computing alignments...  [45.045s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0s]
Sorting trace points...  [1.641s]
Computing alignments...  [44.741s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
 [374.507s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.718s]
Masking reference...  [30.854s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [33.108s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.333s]
Building query seed array...  [1.463s]
Computing hash join...  [4.805s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [53.471s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.08s]
Building query seed array...  [1.691s]
Computing hash join...  [4.816s]
Masking low complexity seeds...  [0.198s]
Searching alignments...  [35.706s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.706s]
Building query seed array...  [1.831s]
Computing hash join...  [4.781s]
Masking low complexity seeds...  [0.198s]
Searching alignments...  [29.932s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.492s]
Building query seed array...  [1.49s]
Computing hash join...  [4.844s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [26.505s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.869s]
Building query seed array...  [1.329s]
Computing hash join...  [4.744s]
Masking low complexity seeds...  [0.187s]
Searching alignments...  [27.622s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.505s]
Building query seed array...  [1.558s]
Computing hash join...  [4.66s]
Masking low complexity seeds...  [0.194s]
Searching alignments...  [21.865s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.844s]
Building query seed array...  [1.659s]
Computing hash join...  [4.711s]
Masking low complexity seeds...  [0.2s]
Searching alignments...  [23.321s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.711s]
Building query seed array...  [1.31s]
Computing hash join...  [4.684s]
Masking low complexity seeds...  [0.194s]
Searching alignments...  [20.407s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.132s]
Clearing query masking...  [1.133s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [9.329s]
Sorting trace points...  [1.747s]
Computing alignments...  [43.052s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.105s]
Sorting trace points...  [1.435s]
Computing alignments...  [43.264s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.133s]
Sorting trace points...  [1.344s]
Computing alignments...  [42.464s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.103s]
Sorting trace points...  [1.711s]
Computing alignments...  [42.643s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.224s]
Sorting trace points...  [1.35s]
Computing alignments...  [44.647s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.145s]
Sorting trace points...  [1.426s]
Computing alignments...  [44.821s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.127s]
Sorting trace points...  [1.642s]
Computing alignments...  [44.96s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0s]
Sorting trace points...  [1.586s]
Computing alignments...  [44.624s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0s]
 [373.214s]
Deallocating reference...  [0.075s]
Loading reference sequences...  [29.481s]
Masking reference...  [30.827s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.864s]
Allocating buffers...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.016s]
Building query seed array...  [1.58s]
Computing hash join...  [4.907s]
Masking low complexity seeds...  [0.196s]
Searching alignments...  [54.617s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.437s]
Building query seed array...  [1.701s]
Computing hash join...  [4.93s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [36.699s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.591s]
Building query seed array...  [1.876s]
Computing hash join...  [4.769s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [31.95s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.105s]
Building query seed array...  [1.455s]
Computing hash join...  [4.811s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [25.721s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.438s]
Building query seed array...  [1.355s]
Computing hash join...  [4.706s]
Masking low complexity seeds...  [0.196s]
Searching alignments...  [26.108s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.389s]
Building query seed array...  [1.571s]
Computing hash join...  [4.771s]
Masking low complexity seeds...  [0.195s]
Searching alignments...  [21.81s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.047s]
Building query seed array...  [1.649s]
Computing hash join...  [4.68s]
Masking low complexity seeds...  [0.188s]
Searching alignments...  [23.458s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.674s]
Building query seed array...  [1.308s]
Computing hash join...  [4.699s]
Masking low complexity seeds...  [0.2s]
Searching alignments...  [20.936s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.138s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [9.304s]
Sorting trace points...  [1.743s]
Computing alignments...  [42.937s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.128s]
Sorting trace points...  [1.633s]
Computing alignments...  [43.238s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.154s]
Sorting trace points...  [1.621s]
Computing alignments...  [42.485s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.106s]
Sorting trace points...  [1.647s]
Computing alignments...  [42.663s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.164s]
Sorting trace points...  [1.723s]
Computing alignments...  [44.633s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.151s]
Sorting trace points...  [1.717s]
Computing alignments...  [44.883s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.114s]
Sorting trace points...  [1.421s]
Computing alignments...  [44.93s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [1.732s]
Computing alignments...  [44.618s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [374.016s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.885s]
Masking reference...  [32.228s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [31.964s]
Allocating buffers...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.288s]
Building query seed array...  [1.463s]
Computing hash join...  [4.939s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [51.038s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.32s]
Building query seed array...  [1.74s]
Computing hash join...  [4.834s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [35.025s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [12.97s]
Building query seed array...  [1.848s]
Computing hash join...  [4.792s]
Masking low complexity seeds...  [0.198s]
Searching alignments...  [30.201s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.327s]
Building query seed array...  [1.497s]
Computing hash join...  [4.83s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [28.163s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.157s]
Building query seed array...  [1.324s]
Computing hash join...  [4.725s]
Masking low complexity seeds...  [0.192s]
Searching alignments...  [25.817s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.213s]
Building query seed array...  [1.551s]
Computing hash join...  [4.644s]
Masking low complexity seeds...  [0.195s]
Searching alignments...  [21.951s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.07s]
Building query seed array...  [1.649s]
Computing hash join...  [4.839s]
Masking low complexity seeds...  [0.198s]
Searching alignments...  [23.063s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.158s]
Building query seed array...  [1.372s]
Computing hash join...  [4.756s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [20.358s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.117s]
Clearing query masking...  [1.07s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [10.383s]
Sorting trace points...  [1.686s]
Computing alignments...  [42.98s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.085s]
Sorting trace points...  [1.248s]
Computing alignments...  [43.235s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.28s]
Computing alignments...  [42.387s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.089s]
Sorting trace points...  [1.6s]
Computing alignments...  [42.626s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.138s]
Sorting trace points...  [1.45s]
Computing alignments...  [44.555s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.141s]
Sorting trace points...  [1.599s]
Computing alignments...  [44.739s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.164s]
Sorting trace points...  [1.745s]
Computing alignments...  [44.842s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.709s]
Computing alignments...  [44.495s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0s]
 [373.527s]
Deallocating reference...  [0.077s]
Loading reference sequences...  [29.801s]
Masking reference...  [32.101s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.685s]
Allocating buffers...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.323s]
Building query seed array...  [1.469s]
Computing hash join...  [4.815s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [51.036s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.753s]
Building query seed array...  [1.83s]
Computing hash join...  [4.934s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [33.701s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.234s]
Building query seed array...  [1.883s]
Computing hash join...  [4.891s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [30.143s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.404s]
Building query seed array...  [1.461s]
Computing hash join...  [4.895s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [26.26s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.028s]
Building query seed array...  [1.366s]
Computing hash join...  [4.681s]
Masking low complexity seeds...  [0.187s]
Searching alignments...  [26.316s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.309s]
Building query seed array...  [1.566s]
Computing hash join...  [4.657s]
Masking low complexity seeds...  [0.187s]
Searching alignments...  [21.494s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.197s]
Building query seed array...  [1.61s]
Computing hash join...  [4.686s]
Masking low complexity seeds...  [0.188s]
Searching alignments...  [23.188s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.844s]
Building query seed array...  [1.333s]
Computing hash join...  [4.731s]
Masking low complexity seeds...  [0.2s]
Searching alignments...  [20.429s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.118s]
Clearing query masking...  [1.133s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [9.794s]
Sorting trace points...  [1.639s]
Computing alignments...  [42.981s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.13s]
Sorting trace points...  [1.725s]
Computing alignments...  [43.292s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.119s]
Sorting trace points...  [1.323s]
Computing alignments...  [42.538s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.13s]
Sorting trace points...  [1.629s]
Computing alignments...  [42.693s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.169s]
Sorting trace points...  [1.396s]
Computing alignments...  [44.736s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.133s]
Sorting trace points...  [1.734s]
Computing alignments...  [44.902s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.136s]
Sorting trace points...  [1.356s]
Computing alignments...  [45.059s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0s]
Sorting trace points...  [1.724s]
Computing alignments...  [44.801s]
Deallocating buffers...  [0.034s]
Loading trace points...  [0s]
 [374.443s]
Deallocating reference...  [0.077s]
Loading reference sequences...  [34.625s]
Masking reference...  [30.843s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.377s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.26s]
Building query seed array...  [1.458s]
Computing hash join...  [4.929s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [51.335s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.448s]
Building query seed array...  [1.686s]
Computing hash join...  [4.879s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [33.378s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.529s]
Building query seed array...  [1.814s]
Computing hash join...  [4.785s]
Masking low complexity seeds...  [0.2s]
Searching alignments...  [29.865s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.302s]
Building query seed array...  [1.492s]
Computing hash join...  [4.874s]
Masking low complexity seeds...  [0.199s]
Searching alignments...  [27.685s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.135s]
Building query seed array...  [1.344s]
Computing hash join...  [4.805s]
Masking low complexity seeds...  [0.189s]
Searching alignments...  [26.202s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.886s]
Building query seed array...  [1.564s]
Computing hash join...  [4.747s]
Masking low complexity seeds...  [0.188s]
Searching alignments...  [21.769s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.441s]
Building query seed array...  [1.596s]
Computing hash join...  [4.833s]
Masking low complexity seeds...  [0.198s]
Searching alignments...  [23.517s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.779s]
Building query seed array...  [1.362s]
Computing hash join...  [4.704s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [20.583s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.119s]
Clearing query masking...  [1.115s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [9.429s]
Sorting trace points...  [1.675s]
Computing alignments...  [43.064s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.652s]
Computing alignments...  [43.353s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.142s]
Sorting trace points...  [1.7s]
Computing alignments...  [42.659s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.111s]
Sorting trace points...  [1.611s]
Computing alignments...  [42.749s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.158s]
Sorting trace points...  [1.757s]
Computing alignments...  [44.762s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.188s]
Sorting trace points...  [1.779s]
Computing alignments...  [44.889s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.57s]
Computing alignments...  [44.964s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0s]
Sorting trace points...  [1.431s]
Computing alignments...  [44.665s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0s]
 [374.747s]
Deallocating reference...  [0.072s]
Loading reference sequences...  [23.797s]
Masking reference...  [26.005s]
Initializing dictionary...  [0.063s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [26.792s]
Allocating buffers...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.186s]
Building query seed array...  [1.443s]
Computing hash join...  [4.004s]
Masking low complexity seeds...  [0.197s]
Searching alignments...  [41.59s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [9.962s]
Building query seed array...  [1.783s]
Computing hash join...  [4.123s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [29.132s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [10.77s]
Building query seed array...  [1.889s]
Computing hash join...  [4.027s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [24.301s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [8.252s]
Building query seed array...  [1.432s]
Computing hash join...  [4.083s]
Masking low complexity seeds...  [0.196s]
Searching alignments...  [21.562s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [8.163s]
Building query seed array...  [1.331s]
Computing hash join...  [3.873s]
Masking low complexity seeds...  [0.194s]
Searching alignments...  [23.247s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [10.222s]
Building query seed array...  [1.564s]
Computing hash join...  [3.898s]
Masking low complexity seeds...  [0.187s]
Searching alignments...  [17.696s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [10.824s]
Building query seed array...  [1.611s]
Computing hash join...  [3.969s]
Masking low complexity seeds...  [0.193s]
Searching alignments...  [19.029s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [8.601s]
Building query seed array...  [1.362s]
Computing hash join...  [3.865s]
Masking low complexity seeds...  [0.185s]
Searching alignments...  [16.609s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.101s]
Clearing query masking...  [1.137s]
Opening temporary output file...  [0.024s]
Computing alignments... Loading trace points...  [12.155s]
Sorting trace points...  [2.179s]
Computing alignments...  [51.493s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.254s]
Sorting trace points...  [2.08s]
Computing alignments...  [51.033s]
Deallocating buffers...  [0.034s]
Loading trace points...  [0.214s]
Sorting trace points...  [2.077s]
Computing alignments...  [51.525s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.181s]
Sorting trace points...  [1.91s]
Computing alignments...  [53.853s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.061s]
Sorting trace points...  [2.03s]
Computing alignments...  [53.201s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
Sorting trace points...  [0.737s]
Computing alignments...  [17.931s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [303.2s]
Deallocating reference...  [0.065s]
Loading reference sequences...  [0.091s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [1270.38s]
 [1270.38s]
Deallocating queries...  [0.045s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [3.527s]
 [4.568s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 13100.5s
Reported 1588940147 pairwise alignments, 1588940147 HSPs.
9304766 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C21_R1.fastp-trim.20230215.fq.gz complete: C21_R1.blastx.meganized.daa

Now MEGANizing C21_R1.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: C21_R1.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 100% (262.1s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.1s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (2,925.4s)
Total reads:        9,304,766
With hits:           9,304,766 
Alignments:      1,585,296,748
Assig. Taxonomy:     7,964,253
Assig. SEED:            75,797
Assig. EGGNOG:          38,995
Assig. GTDB:           269,413
Assig. EC:           1,472,227
Assig. INTERPRO2GO:    844,894
MinSupport set to: 4652
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.4s)
Min-supp. changes:       3,722
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (7.7s)
Min-supp. changes:       2,834
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (16.1s)
Binning reads Syncing
100% (0.3s)
Class. Taxonomy:            72
Class. SEED:               481
Class. EGGNOG:           1,680
Class. GTDB:                19
Class. EC:               2,304
Class. INTERPRO2GO:      7,621
Total time:  3,222s
Peak memory: 28.4 of 195.3G
MEGANization of C21_R1.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C21_R2.fastp-trim.20230215.fq.gz...
388b6281dd2642ab0ecbe6ed58a6feaa  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C21_R2.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C21_R2.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.296s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.727s]
Opening the output file...  [0s]
Loading query sequences...  [52.34s]
Masking queries...  [12.729s]
Algorithm: Double-indexed
Building query histograms...  [15.422s]
Loading reference sequences...  [29.787s]
Masking reference...  [32.142s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.674s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.191s]
Building query seed array...  [1.514s]
Computing hash join...  [5.07s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [50.82s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.399s]
Building query seed array...  [1.716s]
Computing hash join...  [5.089s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [33.52s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.76s]
Building query seed array...  [1.856s]
Computing hash join...  [5.048s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [29.435s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.056s]
Building query seed array...  [1.477s]
Computing hash join...  [4.958s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [26.532s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.767s]
Building query seed array...  [1.379s]
Computing hash join...  [4.774s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [29.273s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.127s]
Building query seed array...  [1.619s]
Computing hash join...  [4.805s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [22.295s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.566s]
Building query seed array...  [1.627s]
Computing hash join...  [4.867s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [24.18s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.752s]
Building query seed array...  [1.359s]
Computing hash join...  [4.908s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [20.229s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.118s]
Clearing query masking...  [1.142s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [9.149s]
Sorting trace points...  [1.691s]
Computing alignments...  [42.79s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.138s]
Sorting trace points...  [1.452s]
Computing alignments...  [43.011s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.135s]
Sorting trace points...  [1.545s]
Computing alignments...  [42.362s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.111s]
Sorting trace points...  [1.64s]
Computing alignments...  [42.288s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.141s]
Sorting trace points...  [1.364s]
Computing alignments...  [45.324s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.136s]
Sorting trace points...  [1.801s]
Computing alignments...  [46.184s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.125s]
Sorting trace points...  [1.848s]
Computing alignments...  [46.314s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.367s]
Computing alignments...  [45.444s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [376.671s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [30.143s]
Masking reference...  [32.175s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.348s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.138s]
Building query seed array...  [1.499s]
Computing hash join...  [5.035s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [51.732s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.565s]
Building query seed array...  [1.711s]
Computing hash join...  [4.993s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [34.796s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.546s]
Building query seed array...  [1.819s]
Computing hash join...  [5.036s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [31.245s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.451s]
Building query seed array...  [1.476s]
Computing hash join...  [4.964s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [26.332s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.985s]
Building query seed array...  [1.323s]
Computing hash join...  [4.894s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [28.375s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.111s]
Building query seed array...  [1.593s]
Computing hash join...  [4.776s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [23.523s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.427s]
Building query seed array...  [1.65s]
Computing hash join...  [4.788s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [23.083s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.099s]
Building query seed array...  [1.352s]
Computing hash join...  [4.872s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [20.319s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.116s]
Clearing query masking...  [1.117s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [9.156s]
Sorting trace points...  [1.691s]
Computing alignments...  [42.601s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.146s]
Sorting trace points...  [1.351s]
Computing alignments...  [42.806s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.092s]
Sorting trace points...  [1.579s]
Computing alignments...  [42.255s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.125s]
Sorting trace points...  [1.332s]
Computing alignments...  [42.237s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.133s]
Sorting trace points...  [1.861s]
Computing alignments...  [45.326s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.134s]
Sorting trace points...  [1.827s]
Computing alignments...  [45.94s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.099s]
Sorting trace points...  [1.544s]
Computing alignments...  [46.23s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
Sorting trace points...  [1.757s]
Computing alignments...  [45.291s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [375.78s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [29.578s]
Masking reference...  [30.927s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.164s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.496s]
Building query seed array...  [1.442s]
Computing hash join...  [5.067s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [51.533s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.03s]
Building query seed array...  [1.684s]
Computing hash join...  [4.947s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [36.153s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.312s]
Building query seed array...  [1.836s]
Computing hash join...  [4.991s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [31.44s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.942s]
Building query seed array...  [1.448s]
Computing hash join...  [5.051s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [27.32s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10s]
Building query seed array...  [1.365s]
Computing hash join...  [4.823s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [29.058s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.161s]
Building query seed array...  [1.568s]
Computing hash join...  [4.824s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [22.432s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.489s]
Building query seed array...  [1.613s]
Computing hash join...  [4.802s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [24.697s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.057s]
Building query seed array...  [1.336s]
Computing hash join...  [4.823s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [20.573s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.118s]
Clearing query masking...  [1.07s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [9.167s]
Sorting trace points...  [1.677s]
Computing alignments...  [42.9s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.12s]
Sorting trace points...  [1.322s]
Computing alignments...  [43.239s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.126s]
Sorting trace points...  [1.359s]
Computing alignments...  [42.436s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.128s]
Sorting trace points...  [1.385s]
Computing alignments...  [42.523s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.15s]
Sorting trace points...  [1.728s]
Computing alignments...  [45.485s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.129s]
Sorting trace points...  [1.632s]
Computing alignments...  [46.201s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.16s]
Sorting trace points...  [1.815s]
Computing alignments...  [46.265s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.635s]
Computing alignments...  [45.406s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
 [378.014s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.821s]
Masking reference...  [32.192s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.042s]
Allocating buffers...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.05s]
Building query seed array...  [1.496s]
Computing hash join...  [5.06s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [50.329s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.202s]
Building query seed array...  [1.725s]
Computing hash join...  [4.983s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [33.887s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.779s]
Building query seed array...  [1.796s]
Computing hash join...  [4.943s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [29.133s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.086s]
Building query seed array...  [1.574s]
Computing hash join...  [4.986s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [28.227s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.02s]
Building query seed array...  [1.34s]
Computing hash join...  [4.808s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [27.651s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.319s]
Building query seed array...  [1.607s]
Computing hash join...  [4.823s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [22.462s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.262s]
Building query seed array...  [1.649s]
Computing hash join...  [4.959s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [23.935s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.997s]
Building query seed array...  [1.353s]
Computing hash join...  [4.788s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [20.533s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.12s]
Clearing query masking...  [1.062s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [9.251s]
Sorting trace points...  [1.669s]
Computing alignments...  [42.711s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.135s]
Sorting trace points...  [1.655s]
Computing alignments...  [42.882s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.13s]
Sorting trace points...  [1.355s]
Computing alignments...  [42.103s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.151s]
Sorting trace points...  [1.289s]
Computing alignments...  [42.215s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.141s]
Sorting trace points...  [1.703s]
Computing alignments...  [45.153s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.124s]
Sorting trace points...  [1.576s]
Computing alignments...  [45.761s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.14s]
Sorting trace points...  [1.641s]
Computing alignments...  [45.977s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0s]
Sorting trace points...  [1.457s]
Computing alignments...  [45.142s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0s]
 [374.687s]
Deallocating reference...  [0.077s]
Loading reference sequences...  [29.535s]
Masking reference...  [31.846s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [31.982s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.309s]
Building query seed array...  [1.456s]
Computing hash join...  [5.051s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [49.799s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.001s]
Building query seed array...  [1.74s]
Computing hash join...  [4.978s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [33.031s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.271s]
Building query seed array...  [1.882s]
Computing hash join...  [4.981s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [29.242s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.084s]
Building query seed array...  [1.43s]
Computing hash join...  [4.912s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [26.446s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.2s]
Building query seed array...  [1.283s]
Computing hash join...  [4.894s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [29.329s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.023s]
Building query seed array...  [1.567s]
Computing hash join...  [4.754s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [23.217s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.833s]
Building query seed array...  [1.632s]
Computing hash join...  [4.805s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [24.18s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.305s]
Building query seed array...  [1.35s]
Computing hash join...  [4.777s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [20.909s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.136s]
Clearing query masking...  [1.12s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [9.195s]
Sorting trace points...  [1.654s]
Computing alignments...  [42.356s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.153s]
Sorting trace points...  [1.299s]
Computing alignments...  [42.782s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.128s]
Sorting trace points...  [1.401s]
Computing alignments...  [41.886s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.178s]
Sorting trace points...  [1.57s]
Computing alignments...  [41.901s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.121s]
Sorting trace points...  [1.704s]
Computing alignments...  [44.937s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.138s]
Sorting trace points...  [1.838s]
Computing alignments...  [45.618s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.137s]
Sorting trace points...  [1.796s]
Computing alignments...  [45.816s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.776s]
Computing alignments...  [45.023s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0s]
 [373.757s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.779s]
Masking reference...  [32.039s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.692s]
Allocating buffers...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.415s]
Building query seed array...  [1.487s]
Computing hash join...  [5.024s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [50.335s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.484s]
Building query seed array...  [1.751s]
Computing hash join...  [4.978s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [35.011s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.266s]
Building query seed array...  [1.871s]
Computing hash join...  [4.974s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [28.867s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.733s]
Building query seed array...  [1.519s]
Computing hash join...  [4.995s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [25.744s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.126s]
Building query seed array...  [1.314s]
Computing hash join...  [4.889s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [26.699s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.198s]
Building query seed array...  [1.627s]
Computing hash join...  [4.81s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [22.382s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.554s]
Building query seed array...  [1.646s]
Computing hash join...  [4.831s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [23.005s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.741s]
Building query seed array...  [1.417s]
Computing hash join...  [4.753s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [19.914s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.121s]
Clearing query masking...  [1.123s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [9.132s]
Sorting trace points...  [1.753s]
Computing alignments...  [42.186s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.147s]
Sorting trace points...  [1.607s]
Computing alignments...  [42.46s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.136s]
Sorting trace points...  [1.452s]
Computing alignments...  [41.741s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.143s]
Sorting trace points...  [1.585s]
Computing alignments...  [41.888s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.133s]
Sorting trace points...  [1.735s]
Computing alignments...  [44.941s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.117s]
Sorting trace points...  [1.453s]
Computing alignments...  [45.509s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.119s]
Sorting trace points...  [1.466s]
Computing alignments...  [45.763s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
Sorting trace points...  [1.442s]
Computing alignments...  [44.937s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
 [372.192s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [31.211s]
Masking reference...  [32.2s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.014s]
Allocating buffers...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.323s]
Building query seed array...  [1.507s]
Computing hash join...  [5.034s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [52.488s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.35s]
Building query seed array...  [1.731s]
Computing hash join...  [4.963s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [34.062s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.427s]
Building query seed array...  [1.844s]
Computing hash join...  [4.883s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [30.398s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.868s]
Building query seed array...  [1.511s]
Computing hash join...  [4.916s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [26.579s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.922s]
Building query seed array...  [1.373s]
Computing hash join...  [4.846s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [28.516s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.361s]
Building query seed array...  [1.592s]
Computing hash join...  [4.779s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [22.388s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.058s]
Building query seed array...  [1.629s]
Computing hash join...  [4.865s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [24.684s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.373s]
Building query seed array...  [1.33s]
Computing hash join...  [4.685s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [20.351s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.119s]
Clearing query masking...  [1.02s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [9.238s]
Sorting trace points...  [1.691s]
Computing alignments...  [42.338s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.145s]
Sorting trace points...  [1.33s]
Computing alignments...  [42.792s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.108s]
Sorting trace points...  [1.337s]
Computing alignments...  [42.038s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.161s]
Sorting trace points...  [1.507s]
Computing alignments...  [42.118s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.118s]
Sorting trace points...  [1.773s]
Computing alignments...  [44.997s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.166s]
Sorting trace points...  [1.759s]
Computing alignments...  [45.679s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.143s]
Sorting trace points...  [1.777s]
Computing alignments...  [46.003s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0s]
Sorting trace points...  [1.723s]
Computing alignments...  [45.135s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [374.371s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [31.044s]
Masking reference...  [32.199s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.329s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.179s]
Building query seed array...  [1.456s]
Computing hash join...  [4.973s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [51.605s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.969s]
Building query seed array...  [1.731s]
Computing hash join...  [4.939s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [33.407s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.405s]
Building query seed array...  [1.832s]
Computing hash join...  [5.031s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [30.015s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.252s]
Building query seed array...  [1.488s]
Computing hash join...  [4.993s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [26.329s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.927s]
Building query seed array...  [1.332s]
Computing hash join...  [4.821s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [27.84s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.72s]
Building query seed array...  [1.589s]
Computing hash join...  [4.712s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [22.449s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.999s]
Building query seed array...  [1.654s]
Computing hash join...  [4.861s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [24.665s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.86s]
Building query seed array...  [1.42s]
Computing hash join...  [4.822s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [20.083s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.119s]
Clearing query masking...  [1.089s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [9.206s]
Sorting trace points...  [1.738s]
Computing alignments...  [42.388s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.106s]
Sorting trace points...  [1.378s]
Computing alignments...  [42.843s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.133s]
Sorting trace points...  [1.488s]
Computing alignments...  [42.174s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.159s]
Sorting trace points...  [1.29s]
Computing alignments...  [42.195s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.151s]
Sorting trace points...  [1.311s]
Computing alignments...  [45.023s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.14s]
Sorting trace points...  [1.844s]
Computing alignments...  [45.899s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.14s]
Sorting trace points...  [1.693s]
Computing alignments...  [46.154s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.723s]
Computing alignments...  [45.293s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
 [375.634s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.61s]
Masking reference...  [30.844s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.758s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.403s]
Building query seed array...  [1.48s]
Computing hash join...  [5.081s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [49.474s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.441s]
Building query seed array...  [1.711s]
Computing hash join...  [5.038s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [33.652s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.422s]
Building query seed array...  [1.847s]
Computing hash join...  [4.938s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [29.891s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.907s]
Building query seed array...  [1.582s]
Computing hash join...  [4.931s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [28.317s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.367s]
Building query seed array...  [1.332s]
Computing hash join...  [4.933s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [27.898s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.453s]
Building query seed array...  [1.586s]
Computing hash join...  [4.904s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [22.39s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.598s]
Building query seed array...  [1.623s]
Computing hash join...  [4.879s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [24.047s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.713s]
Building query seed array...  [1.363s]
Computing hash join...  [4.796s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [21.349s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.139s]
Clearing query masking...  [1.181s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [9.295s]
Sorting trace points...  [1.452s]
Computing alignments...  [42.373s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.161s]
Sorting trace points...  [1.232s]
Computing alignments...  [42.707s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.111s]
Sorting trace points...  [1.629s]
Computing alignments...  [41.979s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.123s]
Sorting trace points...  [1.566s]
Computing alignments...  [42.028s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.144s]
Sorting trace points...  [1.749s]
Computing alignments...  [44.966s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.147s]
Sorting trace points...  [1.718s]
Computing alignments...  [45.759s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.102s]
Sorting trace points...  [1.8s]
Computing alignments...  [45.932s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0s]
Sorting trace points...  [1.638s]
Computing alignments...  [45.08s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
 [373.971s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.813s]
Masking reference...  [32.147s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.612s]
Allocating buffers...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.833s]
Building query seed array...  [1.505s]
Computing hash join...  [5.021s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [51.146s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.417s]
Building query seed array...  [1.746s]
Computing hash join...  [4.987s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [36.257s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.775s]
Building query seed array...  [1.806s]
Computing hash join...  [4.969s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [29.521s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.168s]
Building query seed array...  [1.515s]
Computing hash join...  [4.983s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [26.562s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.119s]
Building query seed array...  [1.332s]
Computing hash join...  [4.844s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [28.14s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.511s]
Building query seed array...  [1.558s]
Computing hash join...  [4.801s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [22.844s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.084s]
Building query seed array...  [1.683s]
Computing hash join...  [4.736s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [24.476s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.084s]
Building query seed array...  [1.328s]
Computing hash join...  [4.921s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [20.38s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.141s]
Clearing query masking...  [1.186s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [9.171s]
Sorting trace points...  [1.664s]
Computing alignments...  [42.219s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.137s]
Sorting trace points...  [1.652s]
Computing alignments...  [42.7s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.148s]
Sorting trace points...  [1.528s]
Computing alignments...  [41.901s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.138s]
Sorting trace points...  [1.56s]
Computing alignments...  [41.969s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.228s]
Sorting trace points...  [1.322s]
Computing alignments...  [45.004s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.111s]
Sorting trace points...  [1.823s]
Computing alignments...  [45.536s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.108s]
Sorting trace points...  [1.806s]
Computing alignments...  [45.738s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0s]
Sorting trace points...  [1.678s]
Computing alignments...  [45.026s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [373.462s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [31.626s]
Masking reference...  [31.18s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.068s]
Allocating buffers...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.695s]
Building query seed array...  [1.52s]
Computing hash join...  [4.926s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [51.135s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.529s]
Building query seed array...  [1.723s]
Computing hash join...  [4.927s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [35.583s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [12.966s]
Building query seed array...  [1.83s]
Computing hash join...  [4.901s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [29.618s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.159s]
Building query seed array...  [1.472s]
Computing hash join...  [4.923s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [25.8s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.943s]
Building query seed array...  [1.313s]
Computing hash join...  [4.807s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [27.825s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.484s]
Building query seed array...  [1.577s]
Computing hash join...  [4.828s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [22.186s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.578s]
Building query seed array...  [1.714s]
Computing hash join...  [4.938s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [23.116s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.764s]
Building query seed array...  [1.33s]
Computing hash join...  [4.843s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [20.15s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.12s]
Clearing query masking...  [1.134s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [9.317s]
Sorting trace points...  [1.625s]
Computing alignments...  [42.218s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.127s]
Sorting trace points...  [1.648s]
Computing alignments...  [42.635s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.146s]
Sorting trace points...  [1.614s]
Computing alignments...  [41.834s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.11s]
Sorting trace points...  [1.605s]
Computing alignments...  [41.837s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.128s]
Sorting trace points...  [1.393s]
Computing alignments...  [44.849s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.14s]
Sorting trace points...  [1.776s]
Computing alignments...  [45.587s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.127s]
Sorting trace points...  [1.822s]
Computing alignments...  [45.65s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.767s]
Computing alignments...  [44.852s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [373.066s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [29.428s]
Masking reference...  [30.845s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [33.169s]
Allocating buffers...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.067s]
Building query seed array...  [1.452s]
Computing hash join...  [5.013s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [51.332s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.282s]
Building query seed array...  [1.731s]
Computing hash join...  [4.959s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [34.898s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.429s]
Building query seed array...  [1.808s]
Computing hash join...  [4.862s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [30.028s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.94s]
Building query seed array...  [1.478s]
Computing hash join...  [5.03s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [26.559s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.873s]
Building query seed array...  [1.347s]
Computing hash join...  [4.804s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [28.222s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.123s]
Building query seed array...  [1.595s]
Computing hash join...  [4.823s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [22.148s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.305s]
Building query seed array...  [1.63s]
Computing hash join...  [4.81s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [24.271s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.936s]
Building query seed array...  [1.34s]
Computing hash join...  [4.757s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [20.539s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.119s]
Clearing query masking...  [1.067s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [9.886s]
Sorting trace points...  [1.639s]
Computing alignments...  [42.39s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.131s]
Sorting trace points...  [1.259s]
Computing alignments...  [42.77s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.088s]
Sorting trace points...  [1.643s]
Computing alignments...  [42.003s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.123s]
Sorting trace points...  [1.584s]
Computing alignments...  [42.135s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.135s]
Sorting trace points...  [1.794s]
Computing alignments...  [45.249s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.12s]
Sorting trace points...  [1.816s]
Computing alignments...  [45.745s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.133s]
Sorting trace points...  [1.476s]
Computing alignments...  [45.901s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
Sorting trace points...  [1.571s]
Computing alignments...  [45.146s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [375.078s]
Deallocating reference...  [0.063s]
Loading reference sequences...  [29.836s]
Masking reference...  [32.2s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.22s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.302s]
Building query seed array...  [1.498s]
Computing hash join...  [5.003s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [51.602s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [13.447s]
Building query seed array...  [1.737s]
Computing hash join...  [4.965s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [32.969s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [12.916s]
Building query seed array...  [1.848s]
Computing hash join...  [4.917s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [30.087s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.816s]
Building query seed array...  [1.465s]
Computing hash join...  [5.062s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [28.458s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.252s]
Building query seed array...  [1.354s]
Computing hash join...  [4.828s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [29.468s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.869s]
Building query seed array...  [1.586s]
Computing hash join...  [4.814s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [22.722s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.925s]
Building query seed array...  [1.66s]
Computing hash join...  [4.758s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [24.527s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.456s]
Building query seed array...  [1.393s]
Computing hash join...  [4.804s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [22.331s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.132s]
Clearing query masking...  [1.098s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [9.379s]
Sorting trace points...  [1.445s]
Computing alignments...  [42.231s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.141s]
Sorting trace points...  [1.656s]
Computing alignments...  [42.563s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.644s]
Computing alignments...  [41.881s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.155s]
Sorting trace points...  [1.536s]
Computing alignments...  [41.877s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.129s]
Sorting trace points...  [1.525s]
Computing alignments...  [44.89s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.78s]
Sorting trace points...  [1.819s]
Computing alignments...  [45.462s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.111s]
Sorting trace points...  [1.822s]
Computing alignments...  [45.814s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.741s]
Computing alignments...  [45.037s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
 [373.993s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [23.733s]
Masking reference...  [25.923s]
Initializing dictionary...  [0.063s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [26.66s]
Allocating buffers...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.43s]
Building query seed array...  [1.561s]
Computing hash join...  [4.051s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [41.888s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [10.394s]
Building query seed array...  [1.72s]
Computing hash join...  [4.194s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [28.243s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [10.891s]
Building query seed array...  [1.835s]
Computing hash join...  [4.123s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [25.416s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [8.096s]
Building query seed array...  [1.454s]
Computing hash join...  [4.07s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [21.995s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [8.054s]
Building query seed array...  [1.316s]
Computing hash join...  [3.987s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [22.179s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [9.885s]
Building query seed array...  [1.656s]
Computing hash join...  [4s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [18.22s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [10.597s]
Building query seed array...  [1.636s]
Computing hash join...  [3.96s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [19.51s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [7.872s]
Building query seed array...  [1.341s]
Computing hash join...  [4.039s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [17.029s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.101s]
Clearing query masking...  [1.127s]
Opening temporary output file...  [0.018s]
Computing alignments... Loading trace points...  [11.717s]
Sorting trace points...  [2.058s]
Computing alignments...  [50.707s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0.405s]
Sorting trace points...  [2.061s]
Computing alignments...  [50.28s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.13s]
Sorting trace points...  [1.734s]
Computing alignments...  [50.981s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.204s]
Sorting trace points...  [1.956s]
Computing alignments...  [54.493s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.065s]
Sorting trace points...  [2.12s]
Computing alignments...  [54.154s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
Sorting trace points...  [0.631s]
Computing alignments...  [17.967s]
Deallocating buffers...  [0.009s]
Loading trace points...  [0s]
 [302.02s]
Deallocating reference...  [0.051s]
Loading reference sequences...  [0.085s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [1269.77s]
 [1269.77s]
Deallocating queries...  [0.038s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [3.584s]
 [4.611s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 13150.6s
Reported 1536337760 pairwise alignments, 1536337760 HSPs.
9567037 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C21_R2.fastp-trim.20230215.fq.gz complete: C21_R2.blastx.meganized.daa

Now MEGANizing C21_R2.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: C21_R2.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 100% (227.6s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.1s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (2,896.6s)
Total reads:        9,567,037
With hits:           9,567,037 
Alignments:      1,533,545,295
Assig. Taxonomy:     8,151,874
Assig. SEED:            72,868
Assig. EGGNOG:          38,927
Assig. GTDB:           262,049
Assig. EC:           1,512,628
Assig. INTERPRO2GO:    839,152
MinSupport set to: 4783
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.4s)
Min-supp. changes:       3,824
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (6.5s)
Min-supp. changes:       3,004
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (17.4s)
Binning reads Syncing
100% (0.3s)
Class. Taxonomy:            71
Class. SEED:               480
Class. EGGNOG:           1,673
Class. GTDB:                17
Class. EC:               2,311
Class. INTERPRO2GO:      7,635
Total time:  3,158s
Peak memory: 29 of 195.3G
MEGANization of C21_R2.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C22_R1.fastp-trim.20230215.fq.gz...
b36d90761e8c79563cf46e247518389a  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C22_R1.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C22_R1.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.298s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.698s]
Opening the output file...  [0s]
Loading query sequences...  [69.978s]
Masking queries...  [18.177s]
Algorithm: Double-indexed
Building query histograms...  [17.228s]
Loading reference sequences...  [29.675s]
Masking reference...  [30.871s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.981s]
Allocating buffers...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.273s]
Building query seed array...  [1.931s]
Computing hash join...  [5.205s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [76.253s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.428s]
Building query seed array...  [2.279s]
Computing hash join...  [5.161s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [46.682s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.577s]
Building query seed array...  [2.461s]
Computing hash join...  [4.936s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [41.436s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.329s]
Building query seed array...  [1.991s]
Computing hash join...  [5.119s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [37.108s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.018s]
Building query seed array...  [1.779s]
Computing hash join...  [4.817s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [39.301s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.346s]
Building query seed array...  [2.093s]
Computing hash join...  [4.852s]
Masking low complexity seeds...  [0.197s]
Searching alignments...  [30.51s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.488s]
Building query seed array...  [2.157s]
Computing hash join...  [4.855s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [32.646s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.865s]
Building query seed array...  [1.849s]
Computing hash join...  [4.849s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [29.689s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.136s]
Clearing query masking...  [1.516s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.406s]
Sorting trace points...  [1.176s]
Computing alignments...  [30.809s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.104s]
Sorting trace points...  [0.956s]
Computing alignments...  [30.577s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.05s]
Sorting trace points...  [0.967s]
Computing alignments...  [31.324s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.044s]
Computing alignments...  [30.713s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.125s]
Computing alignments...  [30.84s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.066s]
Sorting trace points...  [0.985s]
Computing alignments...  [30.927s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.087s]
Sorting trace points...  [1.201s]
Computing alignments...  [30.639s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.14s]
Computing alignments...  [30.48s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0s]
Sorting trace points...  [1.147s]
Computing alignments...  [30.969s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.186s]
Computing alignments...  [31.763s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.216s]
Computing alignments...  [31.619s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.226s]
Computing alignments...  [31.775s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.109s]
Sorting trace points...  [1.179s]
Computing alignments...  [31.69s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.168s]
Computing alignments...  [31.68s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.082s]
Sorting trace points...  [0.932s]
Computing alignments...  [31.725s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.178s]
Computing alignments...  [31.525s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [524.601s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [34.91s]
Masking reference...  [31.092s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.02s]
Building reference histograms...  [32.381s]
Allocating buffers...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.315s]
Building query seed array...  [1.963s]
Computing hash join...  [5.008s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [75.005s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.023s]
Building query seed array...  [2.364s]
Computing hash join...  [5.062s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [47.952s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.438s]
Building query seed array...  [2.417s]
Computing hash join...  [5.035s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [41.349s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.203s]
Building query seed array...  [1.947s]
Computing hash join...  [5.048s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [38.069s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.813s]
Building query seed array...  [1.857s]
Computing hash join...  [4.818s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [38.242s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.153s]
Building query seed array...  [2.067s]
Computing hash join...  [4.763s]
Masking low complexity seeds...  [0.199s]
Searching alignments...  [30.515s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.228s]
Building query seed array...  [2.245s]
Computing hash join...  [4.82s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [32.506s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.13s]
Building query seed array...  [1.83s]
Computing hash join...  [4.769s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [28.863s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.14s]
Clearing query masking...  [1.508s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.028s]
Sorting trace points...  [1.199s]
Computing alignments...  [30.384s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.127s]
Computing alignments...  [30.252s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.664s]
Sorting trace points...  [1.123s]
Computing alignments...  [31.007s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.161s]
Computing alignments...  [30.532s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.067s]
Computing alignments...  [30.651s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.016s]
Computing alignments...  [30.701s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.158s]
Computing alignments...  [30.448s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.054s]
Sorting trace points...  [0.877s]
Computing alignments...  [30.512s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.071s]
Sorting trace points...  [0.876s]
Computing alignments...  [30.934s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.16s]
Computing alignments...  [31.651s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.177s]
Computing alignments...  [31.557s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.056s]
Sorting trace points...  [0.978s]
Computing alignments...  [31.732s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.186s]
Computing alignments...  [31.558s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.186s]
Computing alignments...  [31.6s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.193s]
Computing alignments...  [31.57s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [0.883s]
Computing alignments...  [31.314s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [521.602s]
Deallocating reference...  [0.064s]
Loading reference sequences...  [29.527s]
Masking reference...  [30.853s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.318s]
Allocating buffers...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.408s]
Building query seed array...  [1.983s]
Computing hash join...  [5.024s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [77.326s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.405s]
Building query seed array...  [2.243s]
Computing hash join...  [5.03s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [46.863s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.668s]
Building query seed array...  [2.445s]
Computing hash join...  [5.102s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [41.961s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.097s]
Building query seed array...  [1.967s]
Computing hash join...  [5.005s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [37.973s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.069s]
Building query seed array...  [1.829s]
Computing hash join...  [4.919s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [38.4s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.444s]
Building query seed array...  [2.082s]
Computing hash join...  [4.795s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [30.853s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.268s]
Building query seed array...  [2.206s]
Computing hash join...  [4.785s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [34.292s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.915s]
Building query seed array...  [1.745s]
Computing hash join...  [4.812s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [30.388s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.511s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.48s]
Sorting trace points...  [1.103s]
Computing alignments...  [30.485s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.139s]
Computing alignments...  [30.287s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.032s]
Sorting trace points...  [0.988s]
Computing alignments...  [30.969s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.158s]
Computing alignments...  [30.595s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.156s]
Computing alignments...  [30.815s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.163s]
Sorting trace points...  [1.158s]
Computing alignments...  [30.762s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.207s]
Computing alignments...  [30.607s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.077s]
Sorting trace points...  [0.999s]
Computing alignments...  [30.622s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.071s]
Sorting trace points...  [0.861s]
Computing alignments...  [30.978s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.15s]
Computing alignments...  [31.672s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.221s]
Computing alignments...  [31.519s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.17s]
Computing alignments...  [31.678s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.184s]
Computing alignments...  [31.609s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.109s]
Computing alignments...  [31.556s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.188s]
Computing alignments...  [31.559s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
Sorting trace points...  [1.19s]
Computing alignments...  [31.396s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [522.952s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.528s]
Masking reference...  [32.056s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [31.778s]
Allocating buffers...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.352s]
Building query seed array...  [1.967s]
Computing hash join...  [5.01s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [75.578s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.481s]
Building query seed array...  [2.293s]
Computing hash join...  [4.996s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [47.211s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.231s]
Building query seed array...  [2.492s]
Computing hash join...  [5.013s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [42.971s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.076s]
Building query seed array...  [1.96s]
Computing hash join...  [4.991s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [38.923s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.032s]
Building query seed array...  [1.777s]
Computing hash join...  [4.858s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [37.936s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.987s]
Building query seed array...  [2.076s]
Computing hash join...  [4.788s]
Masking low complexity seeds...  [0.2s]
Searching alignments...  [30.122s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.458s]
Building query seed array...  [2.145s]
Computing hash join...  [4.911s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [32.808s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.146s]
Building query seed array...  [1.763s]
Computing hash join...  [4.849s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [29.498s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.122s]
Clearing query masking...  [1.515s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.029s]
Sorting trace points...  [1.206s]
Computing alignments...  [30.561s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.142s]
Computing alignments...  [30.392s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.138s]
Computing alignments...  [31.065s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.168s]
Computing alignments...  [30.72s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.125s]
Computing alignments...  [30.683s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.147s]
Computing alignments...  [30.912s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.154s]
Computing alignments...  [30.635s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.156s]
Computing alignments...  [30.532s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.457s]
Computing alignments...  [31.019s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.199s]
Computing alignments...  [31.741s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.176s]
Computing alignments...  [31.634s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.213s]
Computing alignments...  [31.77s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.207s]
Computing alignments...  [31.691s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.059s]
Sorting trace points...  [0.891s]
Computing alignments...  [31.69s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.089s]
Sorting trace points...  [0.985s]
Computing alignments...  [31.768s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.155s]
Computing alignments...  [31.447s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
 [524.015s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [29.506s]
Masking reference...  [30.855s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.4s]
Allocating buffers...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [9.883s]
Building query seed array...  [2.005s]
Computing hash join...  [5.018s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [75.542s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.399s]
Building query seed array...  [2.242s]
Computing hash join...  [5.055s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [49.155s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.965s]
Building query seed array...  [2.437s]
Computing hash join...  [4.948s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [42.29s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.317s]
Building query seed array...  [1.956s]
Computing hash join...  [4.946s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [38.59s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.133s]
Building query seed array...  [1.763s]
Computing hash join...  [4.866s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [37.982s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.281s]
Building query seed array...  [2.096s]
Computing hash join...  [4.795s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [30.091s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.303s]
Building query seed array...  [2.268s]
Computing hash join...  [4.858s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [32.645s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.092s]
Building query seed array...  [1.771s]
Computing hash join...  [4.86s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [28.023s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.457s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [5.948s]
Sorting trace points...  [1.115s]
Computing alignments...  [30.346s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.143s]
Computing alignments...  [30.187s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.15s]
Computing alignments...  [30.782s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.099s]
Computing alignments...  [30.444s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.118s]
Computing alignments...  [30.535s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.132s]
Computing alignments...  [30.622s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.137s]
Computing alignments...  [30.412s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.095s]
Computing alignments...  [30.321s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.136s]
Computing alignments...  [30.785s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.19s]
Computing alignments...  [31.559s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.201s]
Computing alignments...  [31.434s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.006s]
Computing alignments...  [31.555s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.191s]
Computing alignments...  [31.459s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.194s]
Sorting trace points...  [1.183s]
Computing alignments...  [31.473s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.199s]
Computing alignments...  [31.499s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.045s]
Computing alignments...  [31.214s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [520.309s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [33.897s]
Masking reference...  [31.504s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [31.53s]
Allocating buffers...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.292s]
Building query seed array...  [1.929s]
Computing hash join...  [5.072s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [74.174s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.544s]
Building query seed array...  [2.277s]
Computing hash join...  [4.979s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [46.115s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.46s]
Building query seed array...  [2.471s]
Computing hash join...  [4.977s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [40.205s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.755s]
Building query seed array...  [1.992s]
Computing hash join...  [5.01s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [36.39s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.768s]
Building query seed array...  [1.829s]
Computing hash join...  [4.822s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [37.041s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.003s]
Building query seed array...  [2.124s]
Computing hash join...  [4.913s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [29.843s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.6s]
Building query seed array...  [2.18s]
Computing hash join...  [4.834s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [33.246s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.003s]
Building query seed array...  [1.784s]
Computing hash join...  [4.887s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [29.299s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.128s]
Clearing query masking...  [1.53s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [5.995s]
Sorting trace points...  [1.202s]
Computing alignments...  [30.201s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.125s]
Computing alignments...  [30.17s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.134s]
Computing alignments...  [30.774s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.132s]
Computing alignments...  [30.29s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.137s]
Computing alignments...  [30.401s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.12s]
Computing alignments...  [30.448s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.064s]
Sorting trace points...  [0.889s]
Computing alignments...  [30.221s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.601s]
Sorting trace points...  [1.108s]
Computing alignments...  [30.159s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.149s]
Computing alignments...  [30.718s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.183s]
Computing alignments...  [31.489s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.192s]
Computing alignments...  [31.319s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.201s]
Computing alignments...  [31.499s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.245s]
Computing alignments...  [31.494s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.085s]
Sorting trace points...  [1.179s]
Computing alignments...  [31.372s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.04s]
Sorting trace points...  [1.202s]
Computing alignments...  [31.438s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.174s]
Computing alignments...  [31.132s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [519.282s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [29.533s]
Masking reference...  [32.149s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.059s]
Allocating buffers...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.404s]
Building query seed array...  [1.968s]
Computing hash join...  [5.059s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [77.055s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.343s]
Building query seed array...  [2.249s]
Computing hash join...  [5.09s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [48.149s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.084s]
Building query seed array...  [2.481s]
Computing hash join...  [5.033s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [43.128s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.195s]
Building query seed array...  [1.997s]
Computing hash join...  [5.03s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [38.476s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.216s]
Building query seed array...  [1.774s]
Computing hash join...  [4.789s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [38.081s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.544s]
Building query seed array...  [2.153s]
Computing hash join...  [4.85s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [29.583s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.294s]
Building query seed array...  [2.173s]
Computing hash join...  [4.801s]
Masking low complexity seeds...  [0.2s]
Searching alignments...  [33.216s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.886s]
Building query seed array...  [1.84s]
Computing hash join...  [4.843s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [29.073s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.514s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.09s]
Sorting trace points...  [1.181s]
Computing alignments...  [30.549s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.08s]
Sorting trace points...  [0.843s]
Computing alignments...  [30.327s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.101s]
Computing alignments...  [30.88s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.157s]
Computing alignments...  [30.653s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.153s]
Computing alignments...  [30.706s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.164s]
Computing alignments...  [30.686s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.176s]
Computing alignments...  [30.592s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.04s]
Computing alignments...  [30.447s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.09s]
Sorting trace points...  [1.152s]
Computing alignments...  [30.908s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.189s]
Computing alignments...  [31.68s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.363s]
Sorting trace points...  [1.143s]
Computing alignments...  [31.52s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.168s]
Computing alignments...  [31.728s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.06s]
Computing alignments...  [31.641s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.167s]
Computing alignments...  [31.573s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.223s]
Computing alignments...  [31.525s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.172s]
Computing alignments...  [31.346s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
 [522.457s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.328s]
Masking reference...  [32.165s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.099s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.337s]
Building query seed array...  [2.012s]
Computing hash join...  [5.037s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [76.793s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.299s]
Building query seed array...  [2.27s]
Computing hash join...  [5.044s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [48.284s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.495s]
Building query seed array...  [2.426s]
Computing hash join...  [5.036s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [43.399s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.253s]
Building query seed array...  [1.954s]
Computing hash join...  [4.976s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [38.458s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.216s]
Building query seed array...  [1.802s]
Computing hash join...  [4.777s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [37.995s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.499s]
Building query seed array...  [2.05s]
Computing hash join...  [4.89s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [30.112s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.89s]
Building query seed array...  [2.174s]
Computing hash join...  [4.845s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [32.791s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.809s]
Building query seed array...  [1.776s]
Computing hash join...  [4.865s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [28.743s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.539s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.697s]
Sorting trace points...  [1.218s]
Computing alignments...  [30.566s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.138s]
Computing alignments...  [30.419s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.108s]
Computing alignments...  [31.024s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.074s]
Sorting trace points...  [0.998s]
Computing alignments...  [30.663s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.053s]
Sorting trace points...  [0.922s]
Computing alignments...  [30.648s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.114s]
Computing alignments...  [30.686s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.149s]
Computing alignments...  [30.546s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.111s]
Computing alignments...  [30.509s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.089s]
Sorting trace points...  [1.126s]
Computing alignments...  [30.952s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.201s]
Computing alignments...  [31.694s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.157s]
Computing alignments...  [31.505s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.909s]
Sorting trace points...  [0.931s]
Computing alignments...  [31.77s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.098s]
Computing alignments...  [31.733s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.171s]
Computing alignments...  [31.624s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.217s]
Computing alignments...  [31.591s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.161s]
Computing alignments...  [31.351s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [523.984s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.789s]
Masking reference...  [31.995s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.329s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.622s]
Building query seed array...  [1.989s]
Computing hash join...  [5.037s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [77.417s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.743s]
Building query seed array...  [2.327s]
Computing hash join...  [5.047s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [46.855s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.572s]
Building query seed array...  [2.412s]
Computing hash join...  [5.049s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [41.136s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.213s]
Building query seed array...  [2.019s]
Computing hash join...  [4.953s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [36.956s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.116s]
Building query seed array...  [1.817s]
Computing hash join...  [4.895s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [37.737s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.463s]
Building query seed array...  [2.118s]
Computing hash join...  [4.819s]
Masking low complexity seeds...  [0.199s]
Searching alignments...  [29.847s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.341s]
Building query seed array...  [2.284s]
Computing hash join...  [4.979s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [32.762s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.134s]
Building query seed array...  [1.76s]
Computing hash join...  [4.769s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [28.674s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.594s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.123s]
Sorting trace points...  [1.154s]
Computing alignments...  [30.421s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.488s]
Sorting trace points...  [1.17s]
Computing alignments...  [30.224s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.113s]
Computing alignments...  [30.958s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.091s]
Computing alignments...  [30.564s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.154s]
Computing alignments...  [30.662s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.072s]
Sorting trace points...  [0.977s]
Computing alignments...  [30.694s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.147s]
Computing alignments...  [30.493s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.057s]
Computing alignments...  [30.51s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.048s]
Computing alignments...  [30.886s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.19s]
Computing alignments...  [31.689s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.142s]
Computing alignments...  [31.526s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.086s]
Sorting trace points...  [0.99s]
Computing alignments...  [31.707s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.009s]
Computing alignments...  [31.587s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.169s]
Computing alignments...  [31.596s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.273s]
Sorting trace points...  [1.179s]
Computing alignments...  [31.563s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.181s]
Computing alignments...  [31.373s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [522.178s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [29.564s]
Masking reference...  [30.902s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.006s]
Building reference histograms...  [33.084s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.341s]
Building query seed array...  [1.929s]
Computing hash join...  [5.069s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [76.189s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.655s]
Building query seed array...  [2.315s]
Computing hash join...  [5.021s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [48.576s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.439s]
Building query seed array...  [2.432s]
Computing hash join...  [4.976s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [41.625s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.917s]
Building query seed array...  [1.942s]
Computing hash join...  [5.064s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [38.316s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.884s]
Building query seed array...  [1.778s]
Computing hash join...  [4.767s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [37.998s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.366s]
Building query seed array...  [2.089s]
Computing hash join...  [4.883s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [29.832s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.199s]
Building query seed array...  [2.243s]
Computing hash join...  [4.844s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [32.702s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.135s]
Building query seed array...  [1.784s]
Computing hash join...  [4.845s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [29.179s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.127s]
Clearing query masking...  [1.465s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.026s]
Sorting trace points...  [1.192s]
Computing alignments...  [30.465s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.158s]
Computing alignments...  [30.21s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.128s]
Computing alignments...  [30.842s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.079s]
Computing alignments...  [30.469s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.196s]
Computing alignments...  [30.635s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.042s]
Sorting trace points...  [1.198s]
Computing alignments...  [30.641s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.921s]
Sorting trace points...  [0.931s]
Computing alignments...  [30.491s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.113s]
Computing alignments...  [30.363s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.154s]
Computing alignments...  [30.928s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.199s]
Computing alignments...  [31.627s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.038s]
Computing alignments...  [31.466s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.178s]
Computing alignments...  [31.598s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.088s]
Sorting trace points...  [1.156s]
Computing alignments...  [31.576s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.08s]
Sorting trace points...  [0.897s]
Computing alignments...  [31.55s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.222s]
Computing alignments...  [31.536s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [0.992s]
Computing alignments...  [31.362s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [521.737s]
Deallocating reference...  [0.071s]
Loading reference sequences...  [29.587s]
Masking reference...  [32.189s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.006s]
Building reference histograms...  [31.78s]
Allocating buffers...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.413s]
Building query seed array...  [1.98s]
Computing hash join...  [5.031s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [75.325s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.276s]
Building query seed array...  [2.326s]
Computing hash join...  [5.121s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [47.594s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.366s]
Building query seed array...  [2.401s]
Computing hash join...  [4.886s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [40.468s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.908s]
Building query seed array...  [1.938s]
Computing hash join...  [4.982s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [37.847s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.95s]
Building query seed array...  [1.766s]
Computing hash join...  [4.809s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [38.461s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.186s]
Building query seed array...  [2.065s]
Computing hash join...  [4.821s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [29.944s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.283s]
Building query seed array...  [2.216s]
Computing hash join...  [4.913s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [33.852s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.129s]
Building query seed array...  [1.785s]
Computing hash join...  [4.805s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [28.298s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.562s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.028s]
Sorting trace points...  [1.24s]
Computing alignments...  [30.417s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.108s]
Sorting trace points...  [1.135s]
Computing alignments...  [30.222s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.132s]
Computing alignments...  [30.869s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.13s]
Computing alignments...  [30.472s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.146s]
Computing alignments...  [30.653s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.177s]
Computing alignments...  [30.674s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.064s]
Sorting trace points...  [0.876s]
Computing alignments...  [30.388s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.083s]
Computing alignments...  [30.48s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.169s]
Computing alignments...  [30.94s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.188s]
Computing alignments...  [31.534s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.06s]
Sorting trace points...  [0.968s]
Computing alignments...  [31.477s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.114s]
Sorting trace points...  [0.91s]
Computing alignments...  [31.656s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.087s]
Sorting trace points...  [1.201s]
Computing alignments...  [31.506s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.141s]
Computing alignments...  [31.629s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.189s]
Computing alignments...  [31.45s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.139s]
Computing alignments...  [31.236s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [520.753s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.585s]
Masking reference...  [30.854s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.653s]
Allocating buffers...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [9.98s]
Building query seed array...  [1.964s]
Computing hash join...  [5.03s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [76.479s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.474s]
Building query seed array...  [2.297s]
Computing hash join...  [5.111s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [46.605s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.503s]
Building query seed array...  [2.399s]
Computing hash join...  [5.049s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [41.062s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.236s]
Building query seed array...  [1.992s]
Computing hash join...  [4.922s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [37.528s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.699s]
Building query seed array...  [1.841s]
Computing hash join...  [4.71s]
Masking low complexity seeds...  [0.198s]
Searching alignments...  [37.752s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.433s]
Building query seed array...  [2.107s]
Computing hash join...  [4.753s]
Masking low complexity seeds...  [0.199s]
Searching alignments...  [30.093s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.037s]
Building query seed array...  [2.182s]
Computing hash join...  [4.88s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [33.8s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.95s]
Building query seed array...  [1.794s]
Computing hash join...  [4.837s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [28.509s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.122s]
Clearing query masking...  [1.517s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.095s]
Sorting trace points...  [1.205s]
Computing alignments...  [30.506s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.069s]
Sorting trace points...  [0.952s]
Computing alignments...  [30.29s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.096s]
Computing alignments...  [30.981s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.3s]
Sorting trace points...  [1.004s]
Computing alignments...  [30.543s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.153s]
Computing alignments...  [30.64s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.161s]
Computing alignments...  [30.714s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.07s]
Sorting trace points...  [0.998s]
Computing alignments...  [30.548s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.143s]
Computing alignments...  [30.398s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.085s]
Sorting trace points...  [1.165s]
Computing alignments...  [30.898s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.203s]
Computing alignments...  [31.636s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.209s]
Computing alignments...  [31.546s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.228s]
Computing alignments...  [31.702s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.096s]
Computing alignments...  [31.562s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.007s]
Computing alignments...  [31.538s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.215s]
Computing alignments...  [31.617s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.108s]
Computing alignments...  [31.403s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [522.072s]
Deallocating reference...  [0.057s]
Loading reference sequences...  [29.439s]
Masking reference...  [32.053s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.322s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.102s]
Building query seed array...  [1.974s]
Computing hash join...  [5.123s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [76.67s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.284s]
Building query seed array...  [2.231s]
Computing hash join...  [5.042s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [48.411s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.829s]
Building query seed array...  [2.447s]
Computing hash join...  [5.01s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [42.891s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.439s]
Building query seed array...  [1.946s]
Computing hash join...  [4.999s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [38.841s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.115s]
Building query seed array...  [1.844s]
Computing hash join...  [4.88s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [38.29s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.611s]
Building query seed array...  [2.089s]
Computing hash join...  [4.913s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [31.224s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.728s]
Building query seed array...  [2.179s]
Computing hash join...  [4.924s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [32.972s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.813s]
Building query seed array...  [1.873s]
Computing hash join...  [4.851s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [29.207s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.135s]
Clearing query masking...  [1.526s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [5.915s]
Sorting trace points...  [1.161s]
Computing alignments...  [30.971s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.112s]
Computing alignments...  [30.178s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.141s]
Computing alignments...  [30.771s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.126s]
Computing alignments...  [30.448s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.229s]
Sorting trace points...  [1.125s]
Computing alignments...  [30.587s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.092s]
Computing alignments...  [30.532s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.173s]
Computing alignments...  [30.448s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.116s]
Computing alignments...  [30.35s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.071s]
Computing alignments...  [30.896s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.195s]
Computing alignments...  [31.559s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.09s]
Computing alignments...  [31.404s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.193s]
Computing alignments...  [31.617s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.185s]
Computing alignments...  [31.489s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.055s]
Sorting trace points...  [0.941s]
Computing alignments...  [31.472s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.211s]
Computing alignments...  [31.456s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.102s]
Computing alignments...  [31.279s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [520.796s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [23.799s]
Masking reference...  [26.079s]
Initializing dictionary...  [0.063s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [26.38s]
Allocating buffers...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.59s]
Building query seed array...  [1.985s]
Computing hash join...  [4.229s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [59.798s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [10.22s]
Building query seed array...  [2.314s]
Computing hash join...  [4.189s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [37.278s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [10.71s]
Building query seed array...  [2.457s]
Computing hash join...  [4.244s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [33.841s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [8.406s]
Building query seed array...  [1.954s]
Computing hash join...  [4.247s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [32.247s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [7.902s]
Building query seed array...  [1.826s]
Computing hash join...  [4.109s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [31.55s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [9.956s]
Building query seed array...  [2.13s]
Computing hash join...  [4.001s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [24.856s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [10.692s]
Building query seed array...  [2.241s]
Computing hash join...  [4.086s]
Masking low complexity seeds...  [0.192s]
Searching alignments...  [26.5s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [8.19s]
Building query seed array...  [1.768s]
Computing hash join...  [4.022s]
Masking low complexity seeds...  [0.195s]
Searching alignments...  [24.718s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.107s]
Clearing query masking...  [1.489s]
Opening temporary output file...  [0.011s]
Computing alignments... Loading trace points...  [10.127s]
Sorting trace points...  [1.983s]
Computing alignments...  [48.36s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.542s]
Computing alignments...  [48.744s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.862s]
Computing alignments...  [48.725s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.128s]
Sorting trace points...  [1.804s]
Computing alignments...  [48.417s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.153s]
Sorting trace points...  [1.98s]
Computing alignments...  [49.625s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.095s]
Sorting trace points...  [1.998s]
Computing alignments...  [50.262s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.142s]
Sorting trace points...  [1.6s]
Computing alignments...  [50.241s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
Sorting trace points...  [1.874s]
Computing alignments...  [49.786s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [419.912s]
Deallocating reference...  [0.047s]
Loading reference sequences...  [0.08s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [1882.21s]
 [1882.21s]
Deallocating queries...  [0.057s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [3.799s]
 [4.928s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 17211s
Reported 2442075740 pairwise alignments, 2442075740 HSPs.
12753809 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C22_R1.fastp-trim.20230215.fq.gz complete: C22_R1.blastx.meganized.daa

Now MEGANizing C22_R1.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: C22_R1.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 80% 100% (274.5s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.3s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (4,553.1s)
Total reads:       12,753,809
With hits:          12,753,809 
Alignments:      2,429,162,577
Assig. Taxonomy:    11,715,589
Assig. SEED:           106,248
Assig. EGGNOG:          50,469
Assig. GTDB:           393,918
Assig. EC:           2,073,594
Assig. INTERPRO2GO:  1,220,490
MinSupport set to: 6376
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.4s)
Min-supp. changes:       4,086
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (11.0s)
Min-supp. changes:       3,006
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (32.9s)
Binning reads Syncing
100% (0.4s)
Class. Taxonomy:            73
Class. SEED:               496
Class. EGGNOG:           1,742
Class. GTDB:                20
Class. EC:               2,339
Class. INTERPRO2GO:      7,839
Total time:  4,882s
Peak memory: 29.5 of 195.3G
MEGANization of C22_R1.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C22_R2.fastp-trim.20230215.fq.gz...
3853dfb6120c13f985fe18680cdd6f78  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C22_R2.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C22_R2.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.306s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.739s]
Opening the output file...  [0s]
Loading query sequences...  [71.176s]
Masking queries...  [17.993s]
Algorithm: Double-indexed
Building query histograms...  [19.594s]
Loading reference sequences...  [29.401s]
Masking reference...  [32.044s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.042s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.318s]
Building query seed array...  [1.944s]
Computing hash join...  [5.277s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [74.825s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.498s]
Building query seed array...  [2.344s]
Computing hash join...  [5.266s]
Masking low complexity seeds...  [0.249s]
Searching alignments...  [49.887s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [14.264s]
Building query seed array...  [2.425s]
Computing hash join...  [5.135s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [42.894s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.836s]
Building query seed array...  [1.938s]
Computing hash join...  [5.145s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [38.724s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.957s]
Building query seed array...  [1.847s]
Computing hash join...  [5.042s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [42.878s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.088s]
Building query seed array...  [2.074s]
Computing hash join...  [4.932s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [31.038s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.623s]
Building query seed array...  [2.225s]
Computing hash join...  [4.949s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [34.861s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.899s]
Building query seed array...  [1.762s]
Computing hash join...  [4.934s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [30.112s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.134s]
Clearing query masking...  [1.568s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.111s]
Sorting trace points...  [1.185s]
Computing alignments...  [30.636s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.061s]
Sorting trace points...  [0.896s]
Computing alignments...  [30.399s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.155s]
Computing alignments...  [30.966s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.115s]
Computing alignments...  [30.162s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.122s]
Computing alignments...  [30.105s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.091s]
Computing alignments...  [29.942s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.131s]
Computing alignments...  [29.959s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.084s]
Sorting trace points...  [0.869s]
Computing alignments...  [31.217s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.059s]
Sorting trace points...  [0.937s]
Computing alignments...  [31.328s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.223s]
Computing alignments...  [32.192s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.262s]
Computing alignments...  [32.388s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.136s]
Computing alignments...  [32.328s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.21s]
Computing alignments...  [32.175s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.225s]
Computing alignments...  [32.348s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.199s]
Computing alignments...  [32.253s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
Sorting trace points...  [1.2s]
Computing alignments...  [31.889s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [525.626s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.555s]
Masking reference...  [32.209s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.408s]
Allocating buffers...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.351s]
Building query seed array...  [2.028s]
Computing hash join...  [5.177s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [74.065s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.763s]
Building query seed array...  [2.31s]
Computing hash join...  [5.212s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [46.458s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.411s]
Building query seed array...  [2.478s]
Computing hash join...  [5.156s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [41.489s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.484s]
Building query seed array...  [2.02s]
Computing hash join...  [5.146s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [36.686s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.025s]
Building query seed array...  [1.817s]
Computing hash join...  [4.842s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [41.165s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.253s]
Building query seed array...  [2.036s]
Computing hash join...  [4.976s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [30.704s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.072s]
Building query seed array...  [2.217s]
Computing hash join...  [4.98s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [33.002s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.929s]
Building query seed array...  [1.763s]
Computing hash join...  [5.042s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [29.06s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.133s]
Clearing query masking...  [1.524s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.069s]
Sorting trace points...  [1.149s]
Computing alignments...  [30.473s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [0.868s]
Computing alignments...  [30.339s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.101s]
Computing alignments...  [30.46s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.06s]
Sorting trace points...  [0.896s]
Computing alignments...  [30.145s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.064s]
Computing alignments...  [29.931s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.072s]
Computing alignments...  [29.919s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.048s]
Computing alignments...  [30.45s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.092s]
Computing alignments...  [30.841s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.289s]
Computing alignments...  [31.277s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.164s]
Computing alignments...  [32.155s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.198s]
Computing alignments...  [32.4s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.196s]
Computing alignments...  [32.221s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.251s]
Computing alignments...  [32.084s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.235s]
Computing alignments...  [32.225s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.249s]
Computing alignments...  [32.365s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.176s]
Computing alignments...  [31.953s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
 [524.451s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.519s]
Masking reference...  [30.915s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.902s]
Allocating buffers...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.038s]
Building query seed array...  [1.984s]
Computing hash join...  [5.135s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [74.117s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.451s]
Building query seed array...  [2.282s]
Computing hash join...  [5.16s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [49.333s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.417s]
Building query seed array...  [2.415s]
Computing hash join...  [5.154s]
Masking low complexity seeds...  [0.249s]
Searching alignments...  [42.757s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.953s]
Building query seed array...  [1.948s]
Computing hash join...  [5.154s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [38.371s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.486s]
Building query seed array...  [1.768s]
Computing hash join...  [4.923s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [41.803s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.156s]
Building query seed array...  [2.06s]
Computing hash join...  [4.955s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [31.809s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.311s]
Building query seed array...  [2.208s]
Computing hash join...  [4.931s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [34.959s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.183s]
Building query seed array...  [1.84s]
Computing hash join...  [5.017s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [29.192s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.129s]
Clearing query masking...  [1.56s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.296s]
Sorting trace points...  [1.225s]
Computing alignments...  [30.699s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.131s]
Computing alignments...  [30.511s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.128s]
Computing alignments...  [30.586s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.067s]
Sorting trace points...  [0.966s]
Computing alignments...  [30.266s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.141s]
Computing alignments...  [30.046s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.034s]
Sorting trace points...  [0.911s]
Computing alignments...  [30.027s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.133s]
Computing alignments...  [29.982s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.117s]
Computing alignments...  [31.295s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.17s]
Sorting trace points...  [1.213s]
Computing alignments...  [31.338s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.239s]
Computing alignments...  [32.265s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.201s]
Computing alignments...  [32.537s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.049s]
Sorting trace points...  [0.955s]
Computing alignments...  [32.327s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.057s]
Computing alignments...  [32.081s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.281s]
Computing alignments...  [32.259s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.219s]
Computing alignments...  [32.147s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [1.218s]
Computing alignments...  [31.817s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
 [525.906s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [29.53s]
Masking reference...  [30.905s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.564s]
Allocating buffers...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.04s]
Building query seed array...  [1.985s]
Computing hash join...  [5.134s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [75.128s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.428s]
Building query seed array...  [2.329s]
Computing hash join...  [5.192s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [46.181s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.195s]
Building query seed array...  [2.494s]
Computing hash join...  [5.074s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [41.015s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.462s]
Building query seed array...  [1.978s]
Computing hash join...  [5.13s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [36.73s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.274s]
Building query seed array...  [2.061s]
Computing hash join...  [5.067s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [40.218s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.005s]
Building query seed array...  [2.139s]
Computing hash join...  [5.014s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [30.872s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.063s]
Building query seed array...  [2.221s]
Computing hash join...  [4.983s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [33.514s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.99s]
Building query seed array...  [1.786s]
Computing hash join...  [4.979s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [30.262s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.12s]
Clearing query masking...  [1.498s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.076s]
Sorting trace points...  [1.155s]
Computing alignments...  [30.491s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.039s]
Sorting trace points...  [0.912s]
Computing alignments...  [30.285s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.004s]
Computing alignments...  [30.394s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.178s]
Computing alignments...  [30.138s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.113s]
Computing alignments...  [29.902s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.143s]
Computing alignments...  [29.889s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.109s]
Computing alignments...  [29.796s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.03s]
Computing alignments...  [30.591s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.185s]
Computing alignments...  [31.189s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.268s]
Computing alignments...  [32.111s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.056s]
Sorting trace points...  [0.916s]
Computing alignments...  [32.358s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.063s]
Sorting trace points...  [0.889s]
Computing alignments...  [32.156s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.171s]
Computing alignments...  [32.001s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.195s]
Computing alignments...  [32.154s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.464s]
Sorting trace points...  [1.22s]
Computing alignments...  [32.12s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [0.995s]
Computing alignments...  [31.783s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [522.514s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [35.131s]
Masking reference...  [31.06s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.482s]
Allocating buffers...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.078s]
Building query seed array...  [1.978s]
Computing hash join...  [5.17s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [73.402s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.758s]
Building query seed array...  [2.369s]
Computing hash join...  [5.118s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [48.68s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.062s]
Building query seed array...  [2.439s]
Computing hash join...  [5.115s]
Masking low complexity seeds...  [0.249s]
Searching alignments...  [42.163s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.208s]
Building query seed array...  [1.934s]
Computing hash join...  [5.125s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [38.857s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.771s]
Building query seed array...  [1.773s]
Computing hash join...  [4.963s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [40.643s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.383s]
Building query seed array...  [2.065s]
Computing hash join...  [4.942s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [31.743s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.622s]
Building query seed array...  [2.2s]
Computing hash join...  [4.945s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [33.919s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.738s]
Building query seed array...  [1.85s]
Computing hash join...  [4.946s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [28.738s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.131s]
Clearing query masking...  [1.542s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.327s]
Sorting trace points...  [1.222s]
Computing alignments...  [30.306s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.028s]
Computing alignments...  [30.1s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.178s]
Computing alignments...  [30.362s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.103s]
Computing alignments...  [30.36s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.059s]
Sorting trace points...  [0.956s]
Computing alignments...  [29.873s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.085s]
Computing alignments...  [29.793s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.099s]
Computing alignments...  [29.771s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.075s]
Computing alignments...  [30.974s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.181s]
Computing alignments...  [31.154s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.244s]
Computing alignments...  [32.017s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.093s]
Computing alignments...  [32.122s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.11s]
Computing alignments...  [32.09s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.224s]
Computing alignments...  [31.875s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.23s]
Computing alignments...  [32.038s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.06s]
Sorting trace points...  [0.903s]
Computing alignments...  [32.038s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.196s]
Computing alignments...  [31.679s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
 [522.023s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.536s]
Masking reference...  [30.848s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.561s]
Allocating buffers...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.312s]
Building query seed array...  [1.968s]
Computing hash join...  [5.165s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [73.597s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.541s]
Building query seed array...  [2.293s]
Computing hash join...  [5.181s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [45.367s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.268s]
Building query seed array...  [2.518s]
Computing hash join...  [5.076s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [41.275s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.884s]
Building query seed array...  [1.932s]
Computing hash join...  [5.169s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [36.828s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.849s]
Building query seed array...  [1.852s]
Computing hash join...  [4.886s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [38.946s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.431s]
Building query seed array...  [2.11s]
Computing hash join...  [4.953s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [30.891s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.511s]
Building query seed array...  [2.239s]
Computing hash join...  [4.892s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [33.667s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.136s]
Building query seed array...  [1.801s]
Computing hash join...  [4.937s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [28.813s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.122s]
Clearing query masking...  [1.521s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.145s]
Sorting trace points...  [1.21s]
Computing alignments...  [29.964s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.137s]
Computing alignments...  [29.868s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.014s]
Computing alignments...  [29.972s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.152s]
Computing alignments...  [29.712s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.051s]
Sorting trace points...  [0.863s]
Computing alignments...  [29.624s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.093s]
Sorting trace points...  [1.136s]
Computing alignments...  [29.663s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.113s]
Computing alignments...  [29.514s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.065s]
Computing alignments...  [29.985s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.048s]
Sorting trace points...  [0.9s]
Computing alignments...  [30.973s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.229s]
Computing alignments...  [31.796s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.057s]
Sorting trace points...  [0.939s]
Computing alignments...  [31.993s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.038s]
Sorting trace points...  [1.183s]
Computing alignments...  [31.871s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.209s]
Computing alignments...  [31.708s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.208s]
Computing alignments...  [31.885s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.19s]
Computing alignments...  [31.762s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.202s]
Computing alignments...  [31.405s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
 [516.753s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [29.496s]
Masking reference...  [32.045s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.516s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.232s]
Building query seed array...  [2.035s]
Computing hash join...  [5.335s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [75.733s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.902s]
Building query seed array...  [2.393s]
Computing hash join...  [5.15s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [46.485s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.854s]
Building query seed array...  [2.448s]
Computing hash join...  [5.131s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [43.065s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.104s]
Building query seed array...  [1.937s]
Computing hash join...  [5.093s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [37.197s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.846s]
Building query seed array...  [1.876s]
Computing hash join...  [4.96s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [42.977s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.136s]
Building query seed array...  [2.053s]
Computing hash join...  [4.91s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [31.225s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.592s]
Building query seed array...  [2.202s]
Computing hash join...  [4.979s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [34.535s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.933s]
Building query seed array...  [1.81s]
Computing hash join...  [4.901s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [28.681s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.136s]
Clearing query masking...  [1.487s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.166s]
Sorting trace points...  [1.216s]
Computing alignments...  [30.579s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.031s]
Sorting trace points...  [1.174s]
Computing alignments...  [30.325s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.09s]
Sorting trace points...  [1.134s]
Computing alignments...  [30.463s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.102s]
Computing alignments...  [30.116s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.138s]
Computing alignments...  [29.969s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.139s]
Computing alignments...  [29.89s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.031s]
Sorting trace points...  [1.016s]
Computing alignments...  [29.894s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.124s]
Computing alignments...  [30.504s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.219s]
Computing alignments...  [31.199s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.231s]
Computing alignments...  [32.147s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.957s]
Sorting trace points...  [1.134s]
Computing alignments...  [32.427s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.192s]
Computing alignments...  [32.31s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.225s]
Computing alignments...  [32.079s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.112s]
Sorting trace points...  [0.912s]
Computing alignments...  [32.294s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.233s]
Computing alignments...  [32.124s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [1.206s]
Computing alignments...  [31.754s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [524.752s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.879s]
Masking reference...  [30.871s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.489s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.454s]
Building query seed array...  [1.982s]
Computing hash join...  [5.141s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [74.193s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.143s]
Building query seed array...  [2.293s]
Computing hash join...  [5.104s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [48.12s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [12.863s]
Building query seed array...  [2.395s]
Computing hash join...  [5.12s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [41.878s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.943s]
Building query seed array...  [2.061s]
Computing hash join...  [5.111s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [39.032s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.997s]
Building query seed array...  [1.843s]
Computing hash join...  [4.971s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [41.789s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.226s]
Building query seed array...  [2.074s]
Computing hash join...  [4.963s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [30.904s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.131s]
Building query seed array...  [2.232s]
Computing hash join...  [4.877s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [34.88s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.996s]
Building query seed array...  [1.805s]
Computing hash join...  [4.892s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [28.943s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.141s]
Clearing query masking...  [1.532s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.299s]
Sorting trace points...  [1.184s]
Computing alignments...  [30.375s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.032s]
Sorting trace points...  [1.134s]
Computing alignments...  [30.113s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.128s]
Computing alignments...  [30.295s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.018s]
Computing alignments...  [29.996s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.102s]
Computing alignments...  [29.94s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.11s]
Computing alignments...  [29.949s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.035s]
Computing alignments...  [29.769s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.135s]
Computing alignments...  [31.112s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.223s]
Computing alignments...  [31.185s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.063s]
Sorting trace points...  [0.997s]
Computing alignments...  [32.115s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.097s]
Sorting trace points...  [1.2s]
Computing alignments...  [32.304s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.255s]
Computing alignments...  [32.282s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.226s]
Computing alignments...  [32.06s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.053s]
Sorting trace points...  [0.929s]
Computing alignments...  [32.179s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.27s]
Computing alignments...  [32.099s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.204s]
Computing alignments...  [31.766s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [523.256s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [29.603s]
Masking reference...  [32.032s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.222s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.267s]
Building query seed array...  [1.93s]
Computing hash join...  [5.128s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [74.935s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.582s]
Building query seed array...  [2.305s]
Computing hash join...  [5.118s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [46.34s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.863s]
Building query seed array...  [2.48s]
Computing hash join...  [5.101s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [42.584s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.251s]
Building query seed array...  [1.968s]
Computing hash join...  [5.117s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [36.802s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.944s]
Building query seed array...  [1.817s]
Computing hash join...  [4.905s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [40.176s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.417s]
Building query seed array...  [2.092s]
Computing hash join...  [4.873s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [30.611s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.038s]
Building query seed array...  [2.23s]
Computing hash join...  [4.89s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [33.764s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.038s]
Building query seed array...  [1.802s]
Computing hash join...  [5.306s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [28.787s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.473s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.12s]
Sorting trace points...  [1.181s]
Computing alignments...  [30.295s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.098s]
Computing alignments...  [30.15s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.095s]
Sorting trace points...  [1.153s]
Computing alignments...  [30.328s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.12s]
Computing alignments...  [29.981s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.056s]
Sorting trace points...  [0.929s]
Computing alignments...  [29.797s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.034s]
Sorting trace points...  [1.103s]
Computing alignments...  [29.765s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.078s]
Sorting trace points...  [0.867s]
Computing alignments...  [29.76s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.032s]
Sorting trace points...  [1.098s]
Computing alignments...  [31.045s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.21s]
Computing alignments...  [31.187s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.175s]
Computing alignments...  [31.984s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.244s]
Computing alignments...  [32.218s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.074s]
Computing alignments...  [32.103s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.313s]
Sorting trace points...  [1.228s]
Computing alignments...  [31.894s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.057s]
Sorting trace points...  [0.954s]
Computing alignments...  [32.098s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.049s]
Computing alignments...  [31.97s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.201s]
Computing alignments...  [31.675s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
 [521.587s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [31.363s]
Masking reference...  [30.825s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [33.112s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.017s]
Building query seed array...  [1.984s]
Computing hash join...  [5.247s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [74.375s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.559s]
Building query seed array...  [2.283s]
Computing hash join...  [5.089s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [48.825s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.44s]
Building query seed array...  [2.405s]
Computing hash join...  [5.131s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [43.826s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.069s]
Building query seed array...  [2.027s]
Computing hash join...  [5.086s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [38.87s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.95s]
Building query seed array...  [1.818s]
Computing hash join...  [4.922s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [42.119s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.113s]
Building query seed array...  [2.067s]
Computing hash join...  [4.966s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [31.169s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.346s]
Building query seed array...  [2.29s]
Computing hash join...  [4.895s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [33.965s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.818s]
Building query seed array...  [1.821s]
Computing hash join...  [4.854s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [29.135s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.127s]
Clearing query masking...  [1.514s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.06s]
Sorting trace points...  [1.21s]
Computing alignments...  [30.412s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.045s]
Sorting trace points...  [0.914s]
Computing alignments...  [30.129s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.118s]
Computing alignments...  [30.271s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.108s]
Computing alignments...  [30.059s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.048s]
Sorting trace points...  [0.951s]
Computing alignments...  [29.892s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.033s]
Sorting trace points...  [1.103s]
Computing alignments...  [29.968s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.139s]
Computing alignments...  [29.704s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.058s]
Sorting trace points...  [0.897s]
Computing alignments...  [30.824s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.1s]
Sorting trace points...  [1.208s]
Computing alignments...  [31.154s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.257s]
Computing alignments...  [32.035s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.064s]
Sorting trace points...  [0.915s]
Computing alignments...  [32.184s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.251s]
Computing alignments...  [32.162s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.085s]
Sorting trace points...  [1.243s]
Computing alignments...  [31.959s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.226s]
Computing alignments...  [32.091s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.236s]
Computing alignments...  [32.017s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.187s]
Computing alignments...  [31.655s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [522.139s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [30.12s]
Masking reference...  [31.035s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.006s]
Building reference histograms...  [32.451s]
Allocating buffers...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.31s]
Building query seed array...  [1.995s]
Computing hash join...  [5.057s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [73.739s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.302s]
Building query seed array...  [2.327s]
Computing hash join...  [5.119s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [45.914s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.403s]
Building query seed array...  [2.398s]
Computing hash join...  [5.087s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [41.318s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.973s]
Building query seed array...  [1.994s]
Computing hash join...  [5.167s]
Masking low complexity seeds...  [0.249s]
Searching alignments...  [36.486s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.822s]
Building query seed array...  [1.798s]
Computing hash join...  [4.844s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [40.186s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.824s]
Building query seed array...  [2.067s]
Computing hash join...  [4.872s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [30.015s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.389s]
Building query seed array...  [2.188s]
Computing hash join...  [4.915s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [34.012s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.479s]
Building query seed array...  [1.767s]
Computing hash join...  [4.928s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [29.284s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.122s]
Clearing query masking...  [1.493s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [5.986s]
Sorting trace points...  [1.173s]
Computing alignments...  [30.243s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.065s]
Sorting trace points...  [0.968s]
Computing alignments...  [30.076s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.057s]
Sorting trace points...  [0.97s]
Computing alignments...  [30.275s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.104s]
Sorting trace points...  [1.114s]
Computing alignments...  [30.105s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.125s]
Computing alignments...  [29.926s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.05s]
Computing alignments...  [29.751s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.001s]
Sorting trace points...  [0.982s]
Computing alignments...  [29.633s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.091s]
Computing alignments...  [30.884s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.046s]
Sorting trace points...  [0.939s]
Computing alignments...  [31.197s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.041s]
Computing alignments...  [31.953s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.229s]
Computing alignments...  [32.104s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.051s]
Computing alignments...  [32.075s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.22s]
Computing alignments...  [31.883s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.206s]
Computing alignments...  [32.06s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.182s]
Computing alignments...  [32.072s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
Sorting trace points...  [1.192s]
Computing alignments...  [31.507s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
 [520.487s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [29.675s]
Masking reference...  [30.852s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.65s]
Allocating buffers...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.362s]
Building query seed array...  [1.975s]
Computing hash join...  [5.225s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [75.067s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.58s]
Building query seed array...  [2.372s]
Computing hash join...  [5.122s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [48.118s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.59s]
Building query seed array...  [2.501s]
Computing hash join...  [5.064s]
Masking low complexity seeds...  [0.249s]
Searching alignments...  [44.183s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.125s]
Building query seed array...  [1.976s]
Computing hash join...  [5.122s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [38.463s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.506s]
Building query seed array...  [1.833s]
Computing hash join...  [5.028s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [40.963s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.147s]
Building query seed array...  [2.077s]
Computing hash join...  [4.886s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [30.97s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.335s]
Building query seed array...  [2.146s]
Computing hash join...  [5.111s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [35.398s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.796s]
Building query seed array...  [1.823s]
Computing hash join...  [4.881s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [28.858s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.485s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.141s]
Sorting trace points...  [1.214s]
Computing alignments...  [30.393s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.109s]
Computing alignments...  [30.144s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.146s]
Computing alignments...  [30.309s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.121s]
Computing alignments...  [30.105s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.114s]
Computing alignments...  [29.842s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.049s]
Sorting trace points...  [0.946s]
Computing alignments...  [29.808s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.24s]
Sorting trace points...  [1.127s]
Computing alignments...  [29.773s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.059s]
Sorting trace points...  [0.92s]
Computing alignments...  [30.807s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.11s]
Sorting trace points...  [1.222s]
Computing alignments...  [31.127s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.216s]
Computing alignments...  [32.106s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.167s]
Computing alignments...  [32.394s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.22s]
Computing alignments...  [32.223s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.065s]
Sorting trace points...  [0.926s]
Computing alignments...  [31.955s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.064s]
Sorting trace points...  [0.982s]
Computing alignments...  [32.202s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.054s]
Sorting trace points...  [0.889s]
Computing alignments...  [32.127s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [0.92s]
Computing alignments...  [31.694s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [521.805s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.616s]
Masking reference...  [30.839s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.831s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.066s]
Building query seed array...  [2.038s]
Computing hash join...  [5.148s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [76.388s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.652s]
Building query seed array...  [2.311s]
Computing hash join...  [5.234s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [47.596s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.572s]
Building query seed array...  [2.531s]
Computing hash join...  [5.078s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [42.247s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.391s]
Building query seed array...  [2s]
Computing hash join...  [5.124s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [37.078s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.833s]
Building query seed array...  [1.818s]
Computing hash join...  [4.964s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [39.994s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.921s]
Building query seed array...  [2.076s]
Computing hash join...  [4.976s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [30.516s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.268s]
Building query seed array...  [2.199s]
Computing hash join...  [4.949s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [35.443s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.16s]
Building query seed array...  [1.812s]
Computing hash join...  [4.993s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [29.634s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.528s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.103s]
Sorting trace points...  [1.191s]
Computing alignments...  [30.384s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.113s]
Computing alignments...  [30.1s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.165s]
Computing alignments...  [30.241s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.088s]
Computing alignments...  [30.047s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.169s]
Computing alignments...  [29.874s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.002s]
Sorting trace points...  [1.063s]
Computing alignments...  [29.722s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.19s]
Computing alignments...  [29.674s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.326s]
Sorting trace points...  [1.128s]
Computing alignments...  [31.483s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.176s]
Computing alignments...  [31.081s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.195s]
Computing alignments...  [32.034s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.23s]
Computing alignments...  [32.22s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.206s]
Computing alignments...  [32.036s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.085s]
Sorting trace points...  [1.217s]
Computing alignments...  [31.847s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.237s]
Computing alignments...  [32.072s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.141s]
Computing alignments...  [31.996s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [0.936s]
Computing alignments...  [31.568s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [522.252s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [23.814s]
Masking reference...  [26.022s]
Initializing dictionary...  [0.063s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [26.146s]
Allocating buffers...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.322s]
Building query seed array...  [1.963s]
Computing hash join...  [4.382s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [59.784s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [10.155s]
Building query seed array...  [2.361s]
Computing hash join...  [4.423s]
Masking low complexity seeds...  [0.302s]
Searching alignments...  [39.737s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [11.031s]
Building query seed array...  [2.471s]
Computing hash join...  [4.197s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [35.708s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [7.939s]
Building query seed array...  [1.984s]
Computing hash join...  [4.278s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [30.107s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [8.08s]
Building query seed array...  [1.86s]
Computing hash join...  [4.133s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [33.416s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [9.931s]
Building query seed array...  [2.124s]
Computing hash join...  [4.151s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [25.15s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [10.8s]
Building query seed array...  [2.168s]
Computing hash join...  [4.058s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [27.55s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [8.125s]
Building query seed array...  [1.76s]
Computing hash join...  [4.098s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [23.568s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.107s]
Clearing query masking...  [1.553s]
Opening temporary output file...  [0.012s]
Computing alignments... Loading trace points...  [10.099s]
Sorting trace points...  [2.016s]
Computing alignments...  [48.043s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.118s]
Sorting trace points...  [1.911s]
Computing alignments...  [47.905s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.785s]
Computing alignments...  [47.485s]
Deallocating buffers...  [0.032s]
Loading trace points...  [0.18s]
Sorting trace points...  [1.866s]
Computing alignments...  [47.677s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.147s]
Sorting trace points...  [1.949s]
Computing alignments...  [50.333s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.162s]
Sorting trace points...  [2.065s]
Computing alignments...  [51.258s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.159s]
Sorting trace points...  [2.066s]
Computing alignments...  [50.958s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
Sorting trace points...  [1.951s]
Computing alignments...  [50.34s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [420.868s]
Deallocating reference...  [0.052s]
Loading reference sequences...  [0.095s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [1871.18s]
 [1871.18s]
Deallocating queries...  [0.056s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [3.787s]
 [5.028s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 17276.4s
Reported 2376215080 pairwise alignments, 2376215080 HSPs.
13050363 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C22_R2.fastp-trim.20230215.fq.gz complete: C22_R2.blastx.meganized.daa

Now MEGANizing C22_R2.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: C22_R2.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 80% 100% (280.1s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.2s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (4,433.1s)
Total reads:       13,050,363
With hits:          13,050,363 
Alignments:      2,366,170,858
Assig. Taxonomy:    11,946,960
Assig. SEED:           102,928
Assig. EGGNOG:          49,802
Assig. GTDB:           381,208
Assig. EC:           2,113,919
Assig. INTERPRO2GO:  1,209,748
MinSupport set to: 6525
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.4s)
Min-supp. changes:       4,175
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (9.3s)
Min-supp. changes:       3,128
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (34.6s)
Binning reads Syncing
100% (0.4s)
Class. Taxonomy:            76
Class. SEED:               498
Class. EGGNOG:           1,743
Class. GTDB:                22
Class. EC:               2,328
Class. INTERPRO2GO:      7,920
Total time:  4,767s
Peak memory: 31.2 of 195.3G
MEGANization of C22_R2.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C23_R1.fastp-trim.20230215.fq.gz...
eb798f626e6da686af1dd28be7dc3752  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C23_R1.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C23_R1.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.38s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.717s]
Opening the output file...  [0s]
Loading query sequences...  [64.457s]
Masking queries...  [16.447s]
Algorithm: Double-indexed
Building query histograms...  [17.231s]
Loading reference sequences...  [29.322s]
Masking reference...  [32.073s]
Initializing dictionary...  [0.08s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.272s]
Allocating buffers...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.088s]
Building query seed array...  [1.794s]
Computing hash join...  [5.189s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [69.821s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.508s]
Building query seed array...  [2.102s]
Computing hash join...  [5.044s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [44.263s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.171s]
Building query seed array...  [2.165s]
Computing hash join...  [4.995s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [39.778s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.941s]
Building query seed array...  [1.774s]
Computing hash join...  [4.989s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [35.371s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.941s]
Building query seed array...  [1.626s]
Computing hash join...  [4.894s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [34.156s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.502s]
Building query seed array...  [1.875s]
Computing hash join...  [4.862s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [27.007s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.383s]
Building query seed array...  [2.057s]
Computing hash join...  [4.86s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [29.709s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.01s]
Building query seed array...  [1.608s]
Computing hash join...  [4.849s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [25.925s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.121s]
Clearing query masking...  [1.445s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [11.497s]
Sorting trace points...  [2.246s]
Computing alignments...  [55.675s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.104s]
Sorting trace points...  [2.113s]
Computing alignments...  [55.653s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.122s]
Sorting trace points...  [1.696s]
Computing alignments...  [54.685s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.134s]
Sorting trace points...  [1.81s]
Computing alignments...  [54.418s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.079s]
Sorting trace points...  [2.229s]
Computing alignments...  [56.373s]
Deallocating buffers...  [0.04s]
Loading trace points...  [0.14s]
Sorting trace points...  [2.207s]
Computing alignments...  [57.019s]
Deallocating buffers...  [0.04s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.755s]
Computing alignments...  [57.675s]
Deallocating buffers...  [0.035s]
Loading trace points...  [0s]
Sorting trace points...  [1.724s]
Computing alignments...  [56.484s]
Deallocating buffers...  [0.039s]
Loading trace points...  [0s]
 [476.395s]
Deallocating reference...  [0.069s]
Loading reference sequences...  [29.619s]
Masking reference...  [30.92s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.84s]
Allocating buffers...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [9.994s]
Building query seed array...  [1.784s]
Computing hash join...  [5.068s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [66.405s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.537s]
Building query seed array...  [2.103s]
Computing hash join...  [5.045s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [43.661s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.145s]
Building query seed array...  [2.229s]
Computing hash join...  [4.964s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [36.647s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.734s]
Building query seed array...  [1.776s]
Computing hash join...  [4.971s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [34.477s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.519s]
Building query seed array...  [1.694s]
Computing hash join...  [4.773s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [34.619s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.266s]
Building query seed array...  [1.859s]
Computing hash join...  [4.843s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [27.063s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.866s]
Building query seed array...  [1.957s]
Computing hash join...  [4.879s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [29.517s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.476s]
Building query seed array...  [1.588s]
Computing hash join...  [4.761s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [25.587s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.119s]
Clearing query masking...  [1.345s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [11.387s]
Sorting trace points...  [2.199s]
Computing alignments...  [55.36s]
Deallocating buffers...  [0.035s]
Loading trace points...  [0.131s]
Sorting trace points...  [2.13s]
Computing alignments...  [54.92s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.149s]
Sorting trace points...  [1.55s]
Computing alignments...  [54.026s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.936s]
Computing alignments...  [53.78s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.175s]
Sorting trace points...  [2.079s]
Computing alignments...  [55.657s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.058s]
Sorting trace points...  [2.243s]
Computing alignments...  [56.699s]
Deallocating buffers...  [0.035s]
Loading trace points...  [0.089s]
Sorting trace points...  [2.185s]
Computing alignments...  [57.007s]
Deallocating buffers...  [0.034s]
Loading trace points...  [0s]
Sorting trace points...  [2.174s]
Computing alignments...  [56.169s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
 [472.587s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [29.573s]
Masking reference...  [32.129s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.617s]
Allocating buffers...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.653s]
Building query seed array...  [1.796s]
Computing hash join...  [5.008s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [69.206s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.368s]
Building query seed array...  [2.056s]
Computing hash join...  [5.047s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [44.208s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.399s]
Building query seed array...  [2.205s]
Computing hash join...  [4.997s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [39.158s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.279s]
Building query seed array...  [1.797s]
Computing hash join...  [4.984s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [35.241s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.831s]
Building query seed array...  [1.658s]
Computing hash join...  [4.812s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [33.957s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.765s]
Building query seed array...  [1.957s]
Computing hash join...  [4.708s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [27.146s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.211s]
Building query seed array...  [1.983s]
Computing hash join...  [4.758s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [29.454s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.115s]
Building query seed array...  [1.607s]
Computing hash join...  [4.862s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [26.559s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.127s]
Clearing query masking...  [1.385s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [11.714s]
Sorting trace points...  [2.233s]
Computing alignments...  [55.435s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.649s]
Computing alignments...  [55.004s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.121s]
Sorting trace points...  [2.101s]
Computing alignments...  [54.186s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.111s]
Sorting trace points...  [2.038s]
Computing alignments...  [53.92s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.084s]
Sorting trace points...  [2.147s]
Computing alignments...  [55.719s]
Deallocating buffers...  [0.036s]
Loading trace points...  [0.167s]
Sorting trace points...  [2.117s]
Computing alignments...  [56.761s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.179s]
Sorting trace points...  [2.245s]
Computing alignments...  [56.953s]
Deallocating buffers...  [0.037s]
Loading trace points...  [0s]
Sorting trace points...  [1.733s]
Computing alignments...  [56.256s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0s]
 [473.351s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [30.14s]
Masking reference...  [30.888s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.991s]
Allocating buffers...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.233s]
Building query seed array...  [1.805s]
Computing hash join...  [5.173s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [67.12s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.74s]
Building query seed array...  [2.095s]
Computing hash join...  [5.023s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [44.808s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.86s]
Building query seed array...  [2.282s]
Computing hash join...  [5.017s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [38.364s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.232s]
Building query seed array...  [1.905s]
Computing hash join...  [5.167s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [33.585s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.687s]
Building query seed array...  [1.674s]
Computing hash join...  [4.839s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [34.694s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.176s]
Building query seed array...  [1.989s]
Computing hash join...  [4.78s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [27.68s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.189s]
Building query seed array...  [2.082s]
Computing hash join...  [4.863s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [29.62s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.97s]
Building query seed array...  [1.616s]
Computing hash join...  [4.805s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [25.677s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.345s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [11.284s]
Sorting trace points...  [2.2s]
Computing alignments...  [55.47s]
Deallocating buffers...  [0.032s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.885s]
Computing alignments...  [55.12s]
Deallocating buffers...  [0.032s]
Loading trace points...  [0.14s]
Sorting trace points...  [1.536s]
Computing alignments...  [54.269s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.122s]
Sorting trace points...  [1.747s]
Computing alignments...  [53.945s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.065s]
Sorting trace points...  [2.155s]
Computing alignments...  [55.897s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.161s]
Sorting trace points...  [1.76s]
Computing alignments...  [56.759s]
Deallocating buffers...  [0.037s]
Loading trace points...  [0.099s]
Sorting trace points...  [1.774s]
Computing alignments...  [56.808s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0s]
Sorting trace points...  [1.735s]
Computing alignments...  [56.269s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0s]
 [471.701s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [29.67s]
Masking reference...  [30.865s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.882s]
Allocating buffers...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [9.996s]
Building query seed array...  [1.796s]
Computing hash join...  [5.047s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [69.057s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.577s]
Building query seed array...  [2.094s]
Computing hash join...  [5.003s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [44.746s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.453s]
Building query seed array...  [2.2s]
Computing hash join...  [4.928s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [38.486s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.258s]
Building query seed array...  [1.776s]
Computing hash join...  [4.997s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [33.571s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.167s]
Building query seed array...  [1.637s]
Computing hash join...  [4.778s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [35.097s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.195s]
Building query seed array...  [1.85s]
Computing hash join...  [4.828s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [27.414s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.93s]
Building query seed array...  [2.009s]
Computing hash join...  [4.862s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [29.538s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.124s]
Building query seed array...  [1.643s]
Computing hash join...  [4.856s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [25.417s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.133s]
Clearing query masking...  [1.409s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [11.494s]
Sorting trace points...  [2.032s]
Computing alignments...  [55.287s]
Deallocating buffers...  [0.036s]
Loading trace points...  [0.152s]
Sorting trace points...  [2.143s]
Computing alignments...  [55.017s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.144s]
Sorting trace points...  [2.077s]
Computing alignments...  [54.171s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.11s]
Sorting trace points...  [2.04s]
Computing alignments...  [53.767s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.161s]
Sorting trace points...  [1.757s]
Computing alignments...  [55.611s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.15s]
Sorting trace points...  [1.693s]
Computing alignments...  [56.625s]
Deallocating buffers...  [0.038s]
Loading trace points...  [0.042s]
Sorting trace points...  [2.124s]
Computing alignments...  [56.817s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0s]
Sorting trace points...  [2.161s]
Computing alignments...  [56.164s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0s]
 [472.18s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [29.616s]
Masking reference...  [30.855s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.859s]
Allocating buffers...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [9.944s]
Building query seed array...  [1.786s]
Computing hash join...  [4.899s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [66.605s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [11.981s]
Building query seed array...  [2.17s]
Computing hash join...  [5.038s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [42.552s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.09s]
Building query seed array...  [2.182s]
Computing hash join...  [4.993s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [37.754s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.101s]
Building query seed array...  [1.751s]
Computing hash join...  [5.013s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [33.872s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.391s]
Building query seed array...  [1.674s]
Computing hash join...  [4.755s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [32.752s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.334s]
Building query seed array...  [1.916s]
Computing hash join...  [4.75s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [27.303s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.016s]
Building query seed array...  [1.951s]
Computing hash join...  [4.936s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [28.854s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.009s]
Building query seed array...  [1.652s]
Computing hash join...  [4.777s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [25.061s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.128s]
Clearing query masking...  [1.405s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [11.365s]
Sorting trace points...  [2.17s]
Computing alignments...  [54.669s]
Deallocating buffers...  [0.035s]
Loading trace points...  [0.114s]
Sorting trace points...  [1.938s]
Computing alignments...  [54.522s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.143s]
Sorting trace points...  [1.832s]
Computing alignments...  [54.233s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.151s]
Sorting trace points...  [2.032s]
Computing alignments...  [53.371s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.135s]
Sorting trace points...  [2.134s]
Computing alignments...  [55.288s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.164s]
Sorting trace points...  [2.131s]
Computing alignments...  [56.154s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.153s]
Sorting trace points...  [2.163s]
Computing alignments...  [56.518s]
Deallocating buffers...  [0.038s]
Loading trace points...  [0s]
Sorting trace points...  [2.085s]
Computing alignments...  [55.822s]
Deallocating buffers...  [0.037s]
Loading trace points...  [0s]
 [469.721s]
Deallocating reference...  [0.074s]
Loading reference sequences...  [35.428s]
Masking reference...  [30.845s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [33.018s]
Allocating buffers...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.132s]
Building query seed array...  [1.787s]
Computing hash join...  [4.952s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [70.041s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.661s]
Building query seed array...  [2.073s]
Computing hash join...  [4.862s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [44.035s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.488s]
Building query seed array...  [2.222s]
Computing hash join...  [4.965s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [38.152s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.182s]
Building query seed array...  [1.748s]
Computing hash join...  [4.993s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [35.616s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.041s]
Building query seed array...  [1.652s]
Computing hash join...  [4.772s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [33.5s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.053s]
Building query seed array...  [1.932s]
Computing hash join...  [4.853s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [27.437s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.549s]
Building query seed array...  [1.987s]
Computing hash join...  [4.799s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [29.899s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.269s]
Building query seed array...  [1.63s]
Computing hash join...  [4.812s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [25.879s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.43s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [11.233s]
Sorting trace points...  [2.213s]
Computing alignments...  [55.469s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.691s]
Computing alignments...  [55.124s]
Deallocating buffers...  [0.035s]
Loading trace points...  [0.116s]
Sorting trace points...  [2.083s]
Computing alignments...  [54.274s]
Deallocating buffers...  [0.032s]
Loading trace points...  [0.108s]
Sorting trace points...  [2.089s]
Computing alignments...  [53.839s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0.09s]
Sorting trace points...  [2.144s]
Computing alignments...  [55.708s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.129s]
Sorting trace points...  [1.641s]
Computing alignments...  [56.644s]
Deallocating buffers...  [0.035s]
Loading trace points...  [0.135s]
Sorting trace points...  [2.157s]
Computing alignments...  [56.88s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0s]
Sorting trace points...  [2.185s]
Computing alignments...  [56.182s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0s]
 [472.643s]
Deallocating reference...  [0.057s]
Loading reference sequences...  [33.164s]
Masking reference...  [31.424s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.715s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.083s]
Building query seed array...  [1.817s]
Computing hash join...  [5.029s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [69.198s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.045s]
Building query seed array...  [2.082s]
Computing hash join...  [4.966s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [43.582s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.479s]
Building query seed array...  [2.186s]
Computing hash join...  [5.039s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [38.612s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.937s]
Building query seed array...  [1.832s]
Computing hash join...  [4.94s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [34.793s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.078s]
Building query seed array...  [1.628s]
Computing hash join...  [4.88s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [33.546s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.219s]
Building query seed array...  [1.933s]
Computing hash join...  [4.746s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [27.025s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.452s]
Building query seed array...  [1.968s]
Computing hash join...  [4.826s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [29.573s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.855s]
Building query seed array...  [1.637s]
Computing hash join...  [4.763s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [25.573s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.42s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [11.421s]
Sorting trace points...  [2.179s]
Computing alignments...  [55.441s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.055s]
Sorting trace points...  [2.067s]
Computing alignments...  [55.015s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.119s]
Sorting trace points...  [2.057s]
Computing alignments...  [54.362s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.103s]
Sorting trace points...  [2.133s]
Computing alignments...  [53.981s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.074s]
Sorting trace points...  [2.178s]
Computing alignments...  [55.862s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.156s]
Sorting trace points...  [1.892s]
Computing alignments...  [56.876s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0.114s]
Sorting trace points...  [2.217s]
Computing alignments...  [56.971s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0s]
Sorting trace points...  [2.14s]
Computing alignments...  [56.221s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
 [474.045s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [34.658s]
Masking reference...  [31.095s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [33.251s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.452s]
Building query seed array...  [1.84s]
Computing hash join...  [4.982s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [68.47s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.352s]
Building query seed array...  [2.111s]
Computing hash join...  [5.005s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [44.161s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.409s]
Building query seed array...  [2.224s]
Computing hash join...  [5.045s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [38.103s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.288s]
Building query seed array...  [1.781s]
Computing hash join...  [4.925s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [34.407s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.958s]
Building query seed array...  [1.7s]
Computing hash join...  [4.813s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [34.522s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.965s]
Building query seed array...  [1.957s]
Computing hash join...  [4.774s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [27.303s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.075s]
Building query seed array...  [2.001s]
Computing hash join...  [4.866s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [30.104s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.048s]
Building query seed array...  [1.613s]
Computing hash join...  [4.838s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [25.853s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.13s]
Clearing query masking...  [1.415s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [11.424s]
Sorting trace points...  [2.186s]
Computing alignments...  [55.134s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.154s]
Sorting trace points...  [1.7s]
Computing alignments...  [55.04s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.145s]
Sorting trace points...  [1.649s]
Computing alignments...  [54.255s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.192s]
Sorting trace points...  [2.113s]
Computing alignments...  [53.939s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.154s]
Sorting trace points...  [2.13s]
Computing alignments...  [55.771s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.122s]
Sorting trace points...  [2.222s]
Computing alignments...  [56.696s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.089s]
Sorting trace points...  [2.098s]
Computing alignments...  [56.856s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0s]
Sorting trace points...  [2.131s]
Computing alignments...  [56.165s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0s]
 [472.758s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [30.973s]
Masking reference...  [31.045s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.106s]
Allocating buffers...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.375s]
Building query seed array...  [1.824s]
Computing hash join...  [5.012s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [69.609s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.68s]
Building query seed array...  [2.101s]
Computing hash join...  [4.894s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [44.512s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.208s]
Building query seed array...  [2.243s]
Computing hash join...  [5.047s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [39.262s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.635s]
Building query seed array...  [1.871s]
Computing hash join...  [4.976s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [34.059s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.316s]
Building query seed array...  [1.659s]
Computing hash join...  [4.792s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [33.783s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.364s]
Building query seed array...  [1.928s]
Computing hash join...  [4.822s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [27.396s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.849s]
Building query seed array...  [2.055s]
Computing hash join...  [4.833s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [29.63s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.537s]
Building query seed array...  [1.621s]
Computing hash join...  [4.795s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [25.592s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.413s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [11.33s]
Sorting trace points...  [2.241s]
Computing alignments...  [55.429s]
Deallocating buffers...  [0.036s]
Loading trace points...  [0.164s]
Sorting trace points...  [1.762s]
Computing alignments...  [55.153s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.152s]
Sorting trace points...  [2.145s]
Computing alignments...  [54.523s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.116s]
Sorting trace points...  [2.07s]
Computing alignments...  [54.329s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.158s]
Sorting trace points...  [2.179s]
Computing alignments...  [56.068s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.167s]
Sorting trace points...  [1.691s]
Computing alignments...  [56.904s]
Deallocating buffers...  [0.035s]
Loading trace points...  [0.048s]
Sorting trace points...  [2.239s]
Computing alignments...  [57s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0s]
Sorting trace points...  [1.61s]
Computing alignments...  [56.433s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0s]
 [474.32s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [31.297s]
Masking reference...  [30.846s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [33.381s]
Allocating buffers...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.636s]
Building query seed array...  [1.851s]
Computing hash join...  [4.946s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [67.465s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.935s]
Building query seed array...  [2.076s]
Computing hash join...  [5.052s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [43.406s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.261s]
Building query seed array...  [2.253s]
Computing hash join...  [4.948s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [38.765s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.273s]
Building query seed array...  [1.787s]
Computing hash join...  [4.986s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [32.75s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.931s]
Building query seed array...  [1.628s]
Computing hash join...  [4.8s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [33.821s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.004s]
Building query seed array...  [1.937s]
Computing hash join...  [4.828s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [27.072s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.084s]
Building query seed array...  [1.969s]
Computing hash join...  [4.85s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [30.195s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.844s]
Building query seed array...  [1.65s]
Computing hash join...  [4.89s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [25.491s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.118s]
Clearing query masking...  [1.403s]
Opening temporary output file...  [0.002s]
Computing alignments... Loading trace points...  [11.441s]
Sorting trace points...  [2.237s]
Computing alignments...  [55.613s]
Deallocating buffers...  [0.036s]
Loading trace points...  [0.125s]
Sorting trace points...  [1.717s]
Computing alignments...  [54.889s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.134s]
Sorting trace points...  [2.141s]
Computing alignments...  [54.18s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.146s]
Sorting trace points...  [1.647s]
Computing alignments...  [53.796s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.157s]
Sorting trace points...  [1.882s]
Computing alignments...  [55.529s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.209s]
Sorting trace points...  [1.717s]
Computing alignments...  [56.464s]
Deallocating buffers...  [0.035s]
Loading trace points...  [0.079s]
Sorting trace points...  [2.231s]
Computing alignments...  [56.799s]
Deallocating buffers...  [0.036s]
Loading trace points...  [0s]
Sorting trace points...  [1.722s]
Computing alignments...  [56.056s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0s]
 [471.36s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.705s]
Masking reference...  [30.854s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [33.544s]
Allocating buffers...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.55s]
Building query seed array...  [1.745s]
Computing hash join...  [5.018s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [67.883s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.676s]
Building query seed array...  [2.131s]
Computing hash join...  [4.895s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [43.472s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.47s]
Building query seed array...  [2.187s]
Computing hash join...  [4.939s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [37.978s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.163s]
Building query seed array...  [1.793s]
Computing hash join...  [4.971s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [35.035s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.286s]
Building query seed array...  [1.657s]
Computing hash join...  [4.817s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [34.469s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.035s]
Building query seed array...  [1.893s]
Computing hash join...  [4.886s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [26.946s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.302s]
Building query seed array...  [1.996s]
Computing hash join...  [4.745s]
Masking low complexity seeds...  [0.2s]
Searching alignments...  [29.507s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.979s]
Building query seed array...  [1.591s]
Computing hash join...  [4.821s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [25.702s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.476s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [11.368s]
Sorting trace points...  [1.796s]
Computing alignments...  [54.943s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.055s]
Sorting trace points...  [2.15s]
Computing alignments...  [54.91s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.142s]
Sorting trace points...  [1.705s]
Computing alignments...  [54.175s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.113s]
Sorting trace points...  [1.769s]
Computing alignments...  [53.877s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.061s]
Sorting trace points...  [2.214s]
Computing alignments...  [55.847s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.13s]
Sorting trace points...  [2.123s]
Computing alignments...  [56.664s]
Deallocating buffers...  [0.038s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.638s]
Computing alignments...  [56.913s]
Deallocating buffers...  [0.035s]
Loading trace points...  [0s]
Sorting trace points...  [1.743s]
Computing alignments...  [56.196s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0s]
 [471.023s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [31.693s]
Masking reference...  [30.856s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [33.291s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.178s]
Building query seed array...  [1.788s]
Computing hash join...  [4.989s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [69.199s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.442s]
Building query seed array...  [2.089s]
Computing hash join...  [5.093s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [44.24s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.254s]
Building query seed array...  [2.244s]
Computing hash join...  [4.984s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [37.977s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.239s]
Building query seed array...  [1.807s]
Computing hash join...  [4.967s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [34.601s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.968s]
Building query seed array...  [1.636s]
Computing hash join...  [4.798s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [33.734s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.992s]
Building query seed array...  [1.947s]
Computing hash join...  [4.813s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [27.356s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.32s]
Building query seed array...  [1.983s]
Computing hash join...  [4.793s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [29.778s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.849s]
Building query seed array...  [1.617s]
Computing hash join...  [4.803s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [26.093s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.139s]
Clearing query masking...  [1.418s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [11.42s]
Sorting trace points...  [2.242s]
Computing alignments...  [55.437s]
Deallocating buffers...  [0.036s]
Loading trace points...  [0.169s]
Sorting trace points...  [2.046s]
Computing alignments...  [54.916s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0.119s]
Sorting trace points...  [1.745s]
Computing alignments...  [54.268s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.074s]
Sorting trace points...  [2.101s]
Computing alignments...  [53.947s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.14s]
Sorting trace points...  [2.103s]
Computing alignments...  [55.684s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.781s]
Computing alignments...  [56.497s]
Deallocating buffers...  [0.037s]
Loading trace points...  [0.069s]
Sorting trace points...  [2.125s]
Computing alignments...  [56.726s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0s]
Sorting trace points...  [1.86s]
Computing alignments...  [55.995s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0s]
 [471.968s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [23.697s]
Masking reference...  [25.029s]
Initializing dictionary...  [0.062s]
Initializing temporary storage...  [0.006s]
Building reference histograms...  [26.594s]
Allocating buffers...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.359s]
Building query seed array...  [1.79s]
Computing hash join...  [4.228s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [55.185s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [10.165s]
Building query seed array...  [2.085s]
Computing hash join...  [4.125s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [34.792s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [10.708s]
Building query seed array...  [2.186s]
Computing hash join...  [4.162s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [31.931s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [8.32s]
Building query seed array...  [1.772s]
Computing hash join...  [4.153s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [28.552s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [8.437s]
Building query seed array...  [1.635s]
Computing hash join...  [4.011s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [27.485s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [10.034s]
Building query seed array...  [1.856s]
Computing hash join...  [4.049s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [22.542s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [10.87s]
Building query seed array...  [1.986s]
Computing hash join...  [3.971s]
Masking low complexity seeds...  [0.198s]
Searching alignments...  [24.152s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [8.013s]
Building query seed array...  [1.704s]
Computing hash join...  [4.013s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [20.885s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.101s]
Clearing query masking...  [1.354s]
Opening temporary output file...  [0.013s]
Computing alignments... Loading trace points...  [9.558s]
Sorting trace points...  [1.783s]
Computing alignments...  [44.076s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.146s]
Sorting trace points...  [1.589s]
Computing alignments...  [43.73s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.163s]
Sorting trace points...  [1.399s]
Computing alignments...  [43.082s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.151s]
Sorting trace points...  [1.42s]
Computing alignments...  [42.814s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.714s]
Computing alignments...  [44.396s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.095s]
Sorting trace points...  [1.751s]
Computing alignments...  [45.083s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.104s]
Sorting trace points...  [1.317s]
Computing alignments...  [45.155s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
Sorting trace points...  [1.809s]
Computing alignments...  [44.645s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
 [376.287s]
Deallocating reference...  [0.047s]
Loading reference sequences...  [0.082s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [1664.09s]
 [1664.09s]
Deallocating queries...  [0.058s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [3.865s]
 [5.01s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 15844.4s
Reported 2159950718 pairwise alignments, 2159950718 HSPs.
11294489 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C23_R1.fastp-trim.20230215.fq.gz complete: C23_R1.blastx.meganized.daa

Now MEGANizing C23_R1.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: C23_R1.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 100% (259.5s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.3s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (3,960.9s)
Total reads:       11,294,489
With hits:          11,294,489 
Alignments:      2,148,996,523
Assig. Taxonomy:    10,197,597
Assig. SEED:           100,931
Assig. EGGNOG:          53,127
Assig. GTDB:           365,551
Assig. EC:           1,821,891
Assig. INTERPRO2GO:  1,090,584
MinSupport set to: 5647
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.3s)
Min-supp. changes:       4,345
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (8.6s)
Min-supp. changes:       3,537
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (31.1s)
Binning reads Syncing
100% (0.5s)
Class. Taxonomy:            88
Class. SEED:               517
Class. EGGNOG:           1,798
Class. GTDB:                23
Class. EC:               2,407
Class. INTERPRO2GO:      7,973
Total time:  4,271s
Peak memory: 33.1 of 195.3G
MEGANization of C23_R1.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C23_R2.fastp-trim.20230215.fq.gz...
8f5cdc876e53ada42ef4b3c01a296f19  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C23_R2.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C23_R2.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.363s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.751s]
Opening the output file...  [0s]
Loading query sequences...  [64.843s]
Masking queries...  [16.279s]
Algorithm: Double-indexed
Building query histograms...  [18.112s]
Loading reference sequences...  [31.37s]
Masking reference...  [32.081s]
Initializing dictionary...  [0.08s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.319s]
Allocating buffers...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.568s]
Building query seed array...  [1.807s]
Computing hash join...  [5.265s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [67.072s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.226s]
Building query seed array...  [2.025s]
Computing hash join...  [5.202s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [41.983s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [12.967s]
Building query seed array...  [2.171s]
Computing hash join...  [5.209s]
Masking low complexity seeds...  [0.259s]
Searching alignments...  [38.261s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.37s]
Building query seed array...  [1.778s]
Computing hash join...  [5.193s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [33.553s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.609s]
Building query seed array...  [1.642s]
Computing hash join...  [4.852s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [37.267s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.483s]
Building query seed array...  [1.885s]
Computing hash join...  [4.94s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [29.293s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.138s]
Building query seed array...  [1.975s]
Computing hash join...  [4.916s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [30.897s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.823s]
Building query seed array...  [1.689s]
Computing hash join...  [4.933s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [25.765s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.122s]
Clearing query masking...  [1.413s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [11.339s]
Sorting trace points...  [2.147s]
Computing alignments...  [55.273s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.069s]
Sorting trace points...  [2.059s]
Computing alignments...  [54.861s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.101s]
Sorting trace points...  [1.593s]
Computing alignments...  [54.032s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0.124s]
Sorting trace points...  [1.723s]
Computing alignments...  [53.656s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.036s]
Sorting trace points...  [1.913s]
Computing alignments...  [56.685s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.1s]
Computing alignments...  [29.171s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.067s]
Computing alignments...  [29.269s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.085s]
Sorting trace points...  [0.938s]
Computing alignments...  [29.225s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.076s]
Sorting trace points...  [0.828s]
Computing alignments...  [29.228s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.102s]
Computing alignments...  [29.142s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0s]
Sorting trace points...  [0.855s]
Computing alignments...  [29.013s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [477.283s]
Deallocating reference...  [0.07s]
Loading reference sequences...  [29.595s]
Masking reference...  [30.891s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.403s]
Allocating buffers...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.255s]
Building query seed array...  [1.806s]
Computing hash join...  [5.177s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [67.961s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.657s]
Building query seed array...  [2.192s]
Computing hash join...  [5.103s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [41.339s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.139s]
Building query seed array...  [2.189s]
Computing hash join...  [5.161s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [37.33s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.433s]
Building query seed array...  [1.779s]
Computing hash join...  [5.112s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [33.034s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.871s]
Building query seed array...  [1.642s]
Computing hash join...  [4.854s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [34.757s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.31s]
Building query seed array...  [1.91s]
Computing hash join...  [4.963s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [27.941s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.489s]
Building query seed array...  [1.995s]
Computing hash join...  [4.96s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [30.228s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.579s]
Building query seed array...  [1.614s]
Computing hash join...  [4.835s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [25.453s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.131s]
Clearing query masking...  [1.43s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [11.339s]
Sorting trace points...  [2.236s]
Computing alignments...  [54.858s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0.141s]
Sorting trace points...  [1.873s]
Computing alignments...  [54.394s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0.14s]
Sorting trace points...  [2.116s]
Computing alignments...  [53.952s]
Deallocating buffers...  [0.035s]
Loading trace points...  [0.159s]
Sorting trace points...  [1.59s]
Computing alignments...  [53.293s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.066s]
Sorting trace points...  [2.187s]
Computing alignments...  [56.191s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.093s]
Computing alignments...  [29.058s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.071s]
Sorting trace points...  [0.838s]
Computing alignments...  [28.984s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.074s]
Computing alignments...  [29.214s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.142s]
Computing alignments...  [29.037s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.126s]
Computing alignments...  [28.983s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [0.852s]
Computing alignments...  [28.817s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
 [476.422s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [30.091s]
Masking reference...  [30.892s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.02s]
Allocating buffers...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.105s]
Building query seed array...  [1.85s]
Computing hash join...  [5.131s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [69.268s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.476s]
Building query seed array...  [2.057s]
Computing hash join...  [5.094s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [42.003s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.778s]
Building query seed array...  [2.292s]
Computing hash join...  [5.01s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [37.701s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.053s]
Building query seed array...  [1.83s]
Computing hash join...  [5.133s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [33.87s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.851s]
Building query seed array...  [1.647s]
Computing hash join...  [4.914s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [35.541s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.512s]
Building query seed array...  [1.917s]
Computing hash join...  [4.925s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [28.239s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.708s]
Building query seed array...  [1.993s]
Computing hash join...  [4.938s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [32.369s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.987s]
Building query seed array...  [1.625s]
Computing hash join...  [4.934s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [26.449s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.41s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [10.539s]
Sorting trace points...  [2.124s]
Computing alignments...  [54.871s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.18s]
Sorting trace points...  [1.881s]
Computing alignments...  [54.532s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.108s]
Sorting trace points...  [1.606s]
Computing alignments...  [53.874s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.14s]
Sorting trace points...  [1.934s]
Computing alignments...  [53.51s]
Deallocating buffers...  [0.038s]
Loading trace points...  [0.054s]
Sorting trace points...  [2.265s]
Computing alignments...  [56.312s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.103s]
Sorting trace points...  [1.058s]
Computing alignments...  [29.058s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.102s]
Computing alignments...  [29.077s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.152s]
Computing alignments...  [29.193s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.001s]
Sorting trace points...  [0.932s]
Computing alignments...  [29.127s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.016s]
Computing alignments...  [29.159s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.085s]
Computing alignments...  [28.807s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0s]
 [475.306s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [29.91s]
Masking reference...  [32.194s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.283s]
Allocating buffers...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.532s]
Building query seed array...  [1.878s]
Computing hash join...  [5.08s]
Masking low complexity seeds...  [0.249s]
Searching alignments...  [68.034s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.414s]
Building query seed array...  [2.12s]
Computing hash join...  [5.109s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [43.125s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [12.703s]
Building query seed array...  [2.223s]
Computing hash join...  [5.082s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [37.756s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.711s]
Building query seed array...  [1.822s]
Computing hash join...  [5.074s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [33.502s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.354s]
Building query seed array...  [1.644s]
Computing hash join...  [4.938s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [35.434s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.071s]
Building query seed array...  [1.938s]
Computing hash join...  [4.863s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [27.713s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.48s]
Building query seed array...  [1.976s]
Computing hash join...  [4.878s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [30.965s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.047s]
Building query seed array...  [1.614s]
Computing hash join...  [4.9s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [26.201s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.116s]
Clearing query masking...  [1.393s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [11.341s]
Sorting trace points...  [2.252s]
Computing alignments...  [55.124s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.135s]
Sorting trace points...  [2.079s]
Computing alignments...  [54.606s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.686s]
Computing alignments...  [53.714s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.134s]
Sorting trace points...  [1.726s]
Computing alignments...  [53.443s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.001s]
Sorting trace points...  [2.251s]
Computing alignments...  [56.48s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.064s]
Computing alignments...  [29.189s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.045s]
Sorting trace points...  [0.837s]
Computing alignments...  [29.08s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.039s]
Sorting trace points...  [0.938s]
Computing alignments...  [29.133s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [0.884s]
Computing alignments...  [29.121s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.139s]
Computing alignments...  [29.048s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0s]
Sorting trace points...  [1.072s]
Computing alignments...  [28.854s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [476.033s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [31.789s]
Masking reference...  [32.175s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [31.837s]
Allocating buffers...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.298s]
Building query seed array...  [1.808s]
Computing hash join...  [5.05s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [65.404s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.167s]
Building query seed array...  [2.104s]
Computing hash join...  [5.068s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [42.626s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.409s]
Building query seed array...  [2.201s]
Computing hash join...  [5.077s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [37.869s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.139s]
Building query seed array...  [1.818s]
Computing hash join...  [5.07s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [33.461s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.78s]
Building query seed array...  [1.634s]
Computing hash join...  [4.867s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [34.652s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.461s]
Building query seed array...  [1.967s]
Computing hash join...  [4.806s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [27.299s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.281s]
Building query seed array...  [2.01s]
Computing hash join...  [4.872s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [31.683s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.058s]
Building query seed array...  [1.666s]
Computing hash join...  [4.932s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [27.168s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.404s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [11.327s]
Sorting trace points...  [2.267s]
Computing alignments...  [54.53s]
Deallocating buffers...  [0.037s]
Loading trace points...  [0.157s]
Sorting trace points...  [1.677s]
Computing alignments...  [54.319s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.098s]
Sorting trace points...  [2.056s]
Computing alignments...  [53.475s]
Deallocating buffers...  [0.032s]
Loading trace points...  [0.149s]
Sorting trace points...  [1.975s]
Computing alignments...  [53.321s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0s]
Sorting trace points...  [2.194s]
Computing alignments...  [56.17s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.071s]
Sorting trace points...  [0.985s]
Computing alignments...  [29.02s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.042s]
Sorting trace points...  [1.119s]
Computing alignments...  [28.912s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.077s]
Computing alignments...  [29.023s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.089s]
Sorting trace points...  [0.879s]
Computing alignments...  [28.996s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.083s]
Computing alignments...  [28.976s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0s]
Sorting trace points...  [0.852s]
Computing alignments...  [28.746s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
 [474.122s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [32.521s]
Masking reference...  [31.31s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.459s]
Allocating buffers...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.349s]
Building query seed array...  [1.826s]
Computing hash join...  [5.188s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [65.079s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.244s]
Building query seed array...  [2.066s]
Computing hash join...  [5.027s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [42.194s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.16s]
Building query seed array...  [2.24s]
Computing hash join...  [5.126s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [37.343s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.86s]
Building query seed array...  [1.775s]
Computing hash join...  [5.153s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [32.923s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.78s]
Building query seed array...  [1.652s]
Computing hash join...  [4.828s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [33.917s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.495s]
Building query seed array...  [1.902s]
Computing hash join...  [4.903s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [27.828s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.117s]
Building query seed array...  [2.02s]
Computing hash join...  [4.962s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [29.331s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.217s]
Building query seed array...  [1.595s]
Computing hash join...  [4.997s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [25.036s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.121s]
Clearing query masking...  [1.372s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [11.107s]
Sorting trace points...  [2.148s]
Computing alignments...  [54.153s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.131s]
Sorting trace points...  [2.106s]
Computing alignments...  [53.765s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.138s]
Sorting trace points...  [1.658s]
Computing alignments...  [53.096s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.121s]
Sorting trace points...  [1.552s]
Computing alignments...  [52.736s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.687s]
Sorting trace points...  [2.171s]
Computing alignments...  [55.724s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.077s]
Sorting trace points...  [0.834s]
Computing alignments...  [28.847s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.095s]
Sorting trace points...  [0.966s]
Computing alignments...  [28.771s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.08s]
Sorting trace points...  [0.915s]
Computing alignments...  [28.891s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.128s]
Computing alignments...  [28.934s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.131s]
Computing alignments...  [28.82s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.065s]
Computing alignments...  [28.651s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [471.064s]
Deallocating reference...  [0.063s]
Loading reference sequences...  [29.302s]
Masking reference...  [30.842s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.929s]
Allocating buffers...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.397s]
Building query seed array...  [1.816s]
Computing hash join...  [5.172s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [68.291s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.39s]
Building query seed array...  [2.061s]
Computing hash join...  [5.178s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [41.73s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.643s]
Building query seed array...  [2.291s]
Computing hash join...  [5.159s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [37.34s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.815s]
Building query seed array...  [1.924s]
Computing hash join...  [5.107s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [33.275s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.247s]
Building query seed array...  [1.651s]
Computing hash join...  [4.981s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [35.75s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.226s]
Building query seed array...  [1.891s]
Computing hash join...  [4.827s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [27.879s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.042s]
Building query seed array...  [2.012s]
Computing hash join...  [4.965s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [31.141s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.89s]
Building query seed array...  [1.609s]
Computing hash join...  [4.879s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [25.999s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.422s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [11.571s]
Sorting trace points...  [2.145s]
Computing alignments...  [54.816s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.128s]
Sorting trace points...  [2.101s]
Computing alignments...  [54.403s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.108s]
Sorting trace points...  [1.663s]
Computing alignments...  [53.457s]
Deallocating buffers...  [0.035s]
Loading trace points...  [0.164s]
Sorting trace points...  [1.796s]
Computing alignments...  [53.391s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.001s]
Sorting trace points...  [2.096s]
Computing alignments...  [56.155s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.065s]
Sorting trace points...  [0.85s]
Computing alignments...  [29.086s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.044s]
Sorting trace points...  [0.874s]
Computing alignments...  [29.05s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.114s]
Computing alignments...  [28.995s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.001s]
Sorting trace points...  [0.962s]
Computing alignments...  [29.062s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.088s]
Computing alignments...  [29.108s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.093s]
Computing alignments...  [28.746s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [474.677s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [29.639s]
Masking reference...  [32.047s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.136s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.398s]
Building query seed array...  [1.861s]
Computing hash join...  [5.053s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [67.818s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.145s]
Building query seed array...  [2.176s]
Computing hash join...  [5.004s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [41.852s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.545s]
Building query seed array...  [2.295s]
Computing hash join...  [5.022s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [37.483s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.926s]
Building query seed array...  [1.898s]
Computing hash join...  [5.082s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [33.587s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.249s]
Building query seed array...  [1.678s]
Computing hash join...  [4.947s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [34.48s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.456s]
Building query seed array...  [1.98s]
Computing hash join...  [4.892s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [28.258s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.778s]
Building query seed array...  [1.954s]
Computing hash join...  [4.831s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [30.215s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.861s]
Building query seed array...  [1.639s]
Computing hash join...  [4.965s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [25.538s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.121s]
Clearing query masking...  [1.345s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [11.378s]
Sorting trace points...  [2.245s]
Computing alignments...  [54.792s]
Deallocating buffers...  [0.032s]
Loading trace points...  [0.164s]
Sorting trace points...  [2.043s]
Computing alignments...  [54.384s]
Deallocating buffers...  [0.038s]
Loading trace points...  [0.111s]
Sorting trace points...  [1.855s]
Computing alignments...  [53.528s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.174s]
Sorting trace points...  [1.964s]
Computing alignments...  [53.209s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.04s]
Sorting trace points...  [1.753s]
Computing alignments...  [56.196s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.127s]
Computing alignments...  [29.089s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.1s]
Computing alignments...  [28.97s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.034s]
Sorting trace points...  [1.124s]
Computing alignments...  [29.056s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.038s]
Sorting trace points...  [0.947s]
Computing alignments...  [29.109s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.1s]
Computing alignments...  [28.996s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.066s]
Computing alignments...  [28.719s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [474.865s]
Deallocating reference...  [0.069s]
Loading reference sequences...  [29.634s]
Masking reference...  [32.019s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.194s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.431s]
Building query seed array...  [1.798s]
Computing hash join...  [5.054s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [67.138s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.129s]
Building query seed array...  [2.094s]
Computing hash join...  [5.038s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [41.495s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.37s]
Building query seed array...  [2.28s]
Computing hash join...  [5.026s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [37.494s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.349s]
Building query seed array...  [1.819s]
Computing hash join...  [5.094s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [33.756s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.398s]
Building query seed array...  [1.656s]
Computing hash join...  [5.082s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [35.446s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.281s]
Building query seed array...  [1.942s]
Computing hash join...  [4.924s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [27.916s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.274s]
Building query seed array...  [1.968s]
Computing hash join...  [4.944s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [31.304s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.011s]
Building query seed array...  [1.632s]
Computing hash join...  [4.902s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [26.344s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.139s]
Clearing query masking...  [1.388s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [12.27s]
Sorting trace points...  [2.19s]
Computing alignments...  [54.604s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.154s]
Sorting trace points...  [2.054s]
Computing alignments...  [54.212s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.995s]
Computing alignments...  [53.474s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.124s]
Sorting trace points...  [2.101s]
Computing alignments...  [53.219s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.958s]
Sorting trace points...  [2.167s]
Computing alignments...  [56.027s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.094s]
Computing alignments...  [28.934s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.001s]
Sorting trace points...  [0.817s]
Computing alignments...  [29.045s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.629s]
Computing alignments...  [29.067s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.088s]
Sorting trace points...  [1.065s]
Computing alignments...  [28.992s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.698s]
Sorting trace points...  [1.349s]
Computing alignments...  [29.059s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.102s]
Computing alignments...  [28.639s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0s]
 [477.705s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.665s]
Masking reference...  [32.044s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.234s]
Allocating buffers...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.456s]
Building query seed array...  [1.847s]
Computing hash join...  [5.237s]
Masking low complexity seeds...  [0.259s]
Searching alignments...  [69.844s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.792s]
Building query seed array...  [2.082s]
Computing hash join...  [5.145s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [43.109s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.327s]
Building query seed array...  [2.237s]
Computing hash join...  [5.113s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [37.122s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.818s]
Building query seed array...  [1.788s]
Computing hash join...  [5.114s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [33.233s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.205s]
Building query seed array...  [1.618s]
Computing hash join...  [4.911s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [35.706s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.484s]
Building query seed array...  [1.897s]
Computing hash join...  [4.887s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [27.766s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.647s]
Building query seed array...  [1.946s]
Computing hash join...  [4.959s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [31.066s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.979s]
Building query seed array...  [1.614s]
Computing hash join...  [4.981s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [25.869s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.119s]
Clearing query masking...  [1.408s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [11.269s]
Sorting trace points...  [2.133s]
Computing alignments...  [54.514s]
Deallocating buffers...  [0.034s]
Loading trace points...  [0.172s]
Sorting trace points...  [1.917s]
Computing alignments...  [54.085s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.069s]
Sorting trace points...  [2.028s]
Computing alignments...  [53.298s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.119s]
Sorting trace points...  [1.952s]
Computing alignments...  [53.18s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.092s]
Sorting trace points...  [2.119s]
Computing alignments...  [56.032s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.044s]
Computing alignments...  [28.99s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.07s]
Computing alignments...  [28.969s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.092s]
Computing alignments...  [28.914s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.114s]
Computing alignments...  [28.993s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.089s]
Computing alignments...  [28.881s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.057s]
Computing alignments...  [28.627s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [473.486s]
Deallocating reference...  [0.066s]
Loading reference sequences...  [29.816s]
Masking reference...  [32.146s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.658s]
Allocating buffers...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.171s]
Building query seed array...  [1.87s]
Computing hash join...  [5.188s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [67.163s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.845s]
Building query seed array...  [2.084s]
Computing hash join...  [5.021s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [41.068s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.867s]
Building query seed array...  [2.183s]
Computing hash join...  [5.097s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [36.579s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.565s]
Building query seed array...  [1.778s]
Computing hash join...  [5.171s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [32.997s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.902s]
Building query seed array...  [1.644s]
Computing hash join...  [4.921s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [35.001s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.43s]
Building query seed array...  [1.903s]
Computing hash join...  [4.937s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [27.723s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.621s]
Building query seed array...  [2.051s]
Computing hash join...  [4.848s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [30.523s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.21s]
Building query seed array...  [1.628s]
Computing hash join...  [4.862s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [25.998s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.121s]
Clearing query masking...  [1.359s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [11.229s]
Sorting trace points...  [2.113s]
Computing alignments...  [54.507s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.152s]
Sorting trace points...  [1.601s]
Computing alignments...  [54.547s]
Deallocating buffers...  [0.032s]
Loading trace points...  [0.157s]
Sorting trace points...  [1.66s]
Computing alignments...  [53.442s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0.119s]
Sorting trace points...  [2.011s]
Computing alignments...  [53.15s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.764s]
Computing alignments...  [55.804s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.679s]
Sorting trace points...  [1.134s]
Computing alignments...  [28.947s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.118s]
Computing alignments...  [28.839s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.389s]
Sorting trace points...  [1.13s]
Computing alignments...  [29.105s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.076s]
Computing alignments...  [28.95s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.123s]
Computing alignments...  [28.999s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.088s]
Computing alignments...  [28.539s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [474.074s]
Deallocating reference...  [0.071s]
Loading reference sequences...  [32.748s]
Masking reference...  [31.862s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [31.962s]
Allocating buffers...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.384s]
Building query seed array...  [1.815s]
Computing hash join...  [5.081s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [68.939s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.482s]
Building query seed array...  [2.146s]
Computing hash join...  [5.109s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [42.116s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.461s]
Building query seed array...  [2.258s]
Computing hash join...  [5.049s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [38.932s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.735s]
Building query seed array...  [1.792s]
Computing hash join...  [5.08s]
Masking low complexity seeds...  [0.256s]
Searching alignments...  [33.507s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.069s]
Building query seed array...  [1.638s]
Computing hash join...  [4.985s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [35.281s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.211s]
Building query seed array...  [1.923s]
Computing hash join...  [4.934s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [28.14s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.046s]
Building query seed array...  [2.01s]
Computing hash join...  [4.906s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [30.727s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.978s]
Building query seed array...  [1.654s]
Computing hash join...  [4.888s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [25.963s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.12s]
Clearing query masking...  [1.378s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [11.295s]
Sorting trace points...  [2.231s]
Computing alignments...  [54.41s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.192s]
Sorting trace points...  [1.731s]
Computing alignments...  [53.956s]
Deallocating buffers...  [0.032s]
Loading trace points...  [0.063s]
Sorting trace points...  [2.015s]
Computing alignments...  [53.276s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0.149s]
Sorting trace points...  [1.681s]
Computing alignments...  [53.173s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.79s]
Computing alignments...  [56.051s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.133s]
Computing alignments...  [28.992s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.04s]
Sorting trace points...  [0.892s]
Computing alignments...  [29.034s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.051s]
Sorting trace points...  [0.993s]
Computing alignments...  [28.998s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.097s]
Computing alignments...  [28.947s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.146s]
Computing alignments...  [28.979s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.087s]
Computing alignments...  [28.602s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0s]
 [472.576s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [34.249s]
Masking reference...  [31.023s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.418s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.238s]
Building query seed array...  [1.856s]
Computing hash join...  [5.127s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [68.156s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.124s]
Building query seed array...  [2.157s]
Computing hash join...  [5.095s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [44.036s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.113s]
Building query seed array...  [2.194s]
Computing hash join...  [5.037s]
Masking low complexity seeds...  [0.256s]
Searching alignments...  [39.572s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.924s]
Building query seed array...  [1.812s]
Computing hash join...  [4.993s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [33.873s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.77s]
Building query seed array...  [1.586s]
Computing hash join...  [4.911s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [36.165s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.231s]
Building query seed array...  [1.938s]
Computing hash join...  [4.924s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [27.581s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.778s]
Building query seed array...  [2.048s]
Computing hash join...  [4.816s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [30.363s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.664s]
Building query seed array...  [1.617s]
Computing hash join...  [4.892s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [25.695s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.122s]
Clearing query masking...  [1.415s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [12.077s]
Sorting trace points...  [1.812s]
Computing alignments...  [54.545s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0.149s]
Sorting trace points...  [2.063s]
Computing alignments...  [54.213s]
Deallocating buffers...  [0.037s]
Loading trace points...  [0.126s]
Sorting trace points...  [1.982s]
Computing alignments...  [53.595s]
Deallocating buffers...  [0.032s]
Loading trace points...  [0.179s]
Sorting trace points...  [2.057s]
Computing alignments...  [53.078s]
Deallocating buffers...  [0.037s]
Loading trace points...  [0.073s]
Sorting trace points...  [2.188s]
Computing alignments...  [55.93s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.065s]
Computing alignments...  [28.99s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.081s]
Computing alignments...  [28.903s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.001s]
Sorting trace points...  [0.935s]
Computing alignments...  [29.07s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.071s]
Sorting trace points...  [0.961s]
Computing alignments...  [29.004s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.122s]
Computing alignments...  [28.942s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.108s]
Computing alignments...  [28.6s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0s]
 [474.472s]
Deallocating reference...  [0.066s]
Loading reference sequences...  [23.741s]
Masking reference...  [26.016s]
Initializing dictionary...  [0.064s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [26.364s]
Allocating buffers...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.631s]
Building query seed array...  [1.827s]
Computing hash join...  [4.211s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [55.024s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [9.975s]
Building query seed array...  [2.114s]
Computing hash join...  [4.297s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [36.47s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [10.983s]
Building query seed array...  [2.209s]
Computing hash join...  [4.239s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [32.143s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [8.263s]
Building query seed array...  [1.801s]
Computing hash join...  [4.259s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [27.342s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [8.11s]
Building query seed array...  [1.653s]
Computing hash join...  [4.091s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [29.932s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [9.847s]
Building query seed array...  [1.827s]
Computing hash join...  [4.035s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [22.836s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [10.665s]
Building query seed array...  [1.991s]
Computing hash join...  [4.047s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [24.062s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [8.42s]
Building query seed array...  [1.634s]
Computing hash join...  [4.101s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [20.94s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.102s]
Clearing query masking...  [1.435s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [9.554s]
Sorting trace points...  [1.754s]
Computing alignments...  [43.471s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.1s]
Sorting trace points...  [1.677s]
Computing alignments...  [43.024s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.151s]
Sorting trace points...  [1.346s]
Computing alignments...  [42.419s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.162s]
Sorting trace points...  [1.495s]
Computing alignments...  [42.287s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.155s]
Sorting trace points...  [1.753s]
Computing alignments...  [44.879s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.002s]
Sorting trace points...  [1.849s]
Computing alignments...  [46.05s]
Deallocating buffers...  [0.032s]
Loading trace points...  [0.159s]
Sorting trace points...  [1.88s]
Computing alignments...  [45.967s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.768s]
Computing alignments...  [45.516s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [377.708s]
Deallocating reference...  [0.05s]
Loading reference sequences...  [0.072s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [1654.15s]
 [1654.15s]
Deallocating queries...  [0.054s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [3.878s]
 [5.013s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 15871.5s
Reported 2101609212 pairwise alignments, 2101609212 HSPs.
11575272 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C23_R2.fastp-trim.20230215.fq.gz complete: C23_R2.blastx.meganized.daa

Now MEGANizing C23_R2.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: C23_R2.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 100% (260.0s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.3s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (3,960.0s)
Total reads:       11,575,272
With hits:          11,575,272 
Alignments:      2,093,584,520
Assig. Taxonomy:    10,418,462
Assig. SEED:            99,090
Assig. EGGNOG:          52,628
Assig. GTDB:           356,897
Assig. EC:           1,857,794
Assig. INTERPRO2GO:  1,084,954
MinSupport set to: 5787
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.5s)
Min-supp. changes:       4,487
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (9.5s)
Min-supp. changes:       3,718
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (27.3s)
Binning reads Syncing
100% (0.4s)
Class. Taxonomy:            87
Class. SEED:               517
Class. EGGNOG:           1,771
Class. GTDB:                21
Class. EC:               2,398
Class. INTERPRO2GO:      8,067
Total time:  4,267s
Peak memory: 36 of 195.3G
MEGANization of C23_R2.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C24_R1.fastp-trim.20230215.fq.gz...
f1fe111cce9cab5f50b04a59fb85363f  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C24_R1.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C24_R1.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.328s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.715s]
Opening the output file...  [0s]
Loading query sequences...  [68.618s]
Masking queries...  [17.751s]
Algorithm: Double-indexed
Building query histograms...  [17.222s]
Loading reference sequences...  [30.1s]
Masking reference...  [30.903s]
Initializing dictionary...  [0.08s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.042s]
Allocating buffers...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.229s]
Building query seed array...  [1.906s]
Computing hash join...  [5.175s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [73.212s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.453s]
Building query seed array...  [2.218s]
Computing hash join...  [5.061s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [44.77s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.759s]
Building query seed array...  [2.401s]
Computing hash join...  [5.001s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [41.065s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.007s]
Building query seed array...  [1.988s]
Computing hash join...  [4.954s]
Masking low complexity seeds...  [0.199s]
Searching alignments...  [35.504s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.008s]
Building query seed array...  [1.787s]
Computing hash join...  [4.873s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [36.605s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.104s]
Building query seed array...  [1.998s]
Computing hash join...  [4.866s]
Masking low complexity seeds...  [0.192s]
Searching alignments...  [29.674s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.278s]
Building query seed array...  [2.104s]
Computing hash join...  [4.834s]
Masking low complexity seeds...  [0.199s]
Searching alignments...  [32.716s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.088s]
Building query seed array...  [1.817s]
Computing hash join...  [4.785s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [27.626s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.486s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.016s]
Sorting trace points...  [1.145s]
Computing alignments...  [30.063s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.128s]
Computing alignments...  [29.92s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.141s]
Computing alignments...  [30.143s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.068s]
Computing alignments...  [29.736s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.122s]
Sorting trace points...  [1.077s]
Computing alignments...  [29.876s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.084s]
Sorting trace points...  [1.783s]
Computing alignments...  [57.899s]
Deallocating buffers...  [0.038s]
Loading trace points...  [0.065s]
Sorting trace points...  [0.992s]
Computing alignments...  [28.908s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.121s]
Computing alignments...  [29.379s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.097s]
Computing alignments...  [30.059s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.13s]
Computing alignments...  [29.991s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.112s]
Computing alignments...  [30.025s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.119s]
Computing alignments...  [30.253s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.087s]
Sorting trace points...  [1.16s]
Computing alignments...  [30.48s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.142s]
Computing alignments...  [30.518s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [0.967s]
Computing alignments...  [29.878s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
 [501.533s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [31.024s]
Masking reference...  [31.096s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.68s]
Allocating buffers...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.685s]
Building query seed array...  [1.92s]
Computing hash join...  [5.07s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [71.935s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.797s]
Building query seed array...  [2.216s]
Computing hash join...  [4.947s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [45.391s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.882s]
Building query seed array...  [2.391s]
Computing hash join...  [4.988s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [40.568s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.319s]
Building query seed array...  [1.89s]
Computing hash join...  [4.949s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [35.694s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.076s]
Building query seed array...  [1.713s]
Computing hash join...  [4.774s]
Masking low complexity seeds...  [0.187s]
Searching alignments...  [35.855s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.392s]
Building query seed array...  [2.023s]
Computing hash join...  [4.764s]
Masking low complexity seeds...  [0.191s]
Searching alignments...  [30.253s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.41s]
Building query seed array...  [2.157s]
Computing hash join...  [4.79s]
Masking low complexity seeds...  [0.189s]
Searching alignments...  [31.105s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.084s]
Building query seed array...  [1.701s]
Computing hash join...  [4.826s]
Masking low complexity seeds...  [0.187s]
Searching alignments...  [27.155s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.418s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [5.969s]
Sorting trace points...  [1.145s]
Computing alignments...  [29.631s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.151s]
Computing alignments...  [29.758s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.109s]
Computing alignments...  [30.064s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.117s]
Sorting trace points...  [0.996s]
Computing alignments...  [29.903s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.758s]
Sorting trace points...  [1.877s]
Computing alignments...  [58.063s]
Deallocating buffers...  [0.036s]
Loading trace points...  [0.236s]
Sorting trace points...  [1.859s]
Computing alignments...  [57.498s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.164s]
Sorting trace points...  [0.995s]
Computing alignments...  [29.209s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.071s]
Sorting trace points...  [0.964s]
Computing alignments...  [29.965s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.108s]
Computing alignments...  [29.914s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.072s]
Computing alignments...  [30.07s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.052s]
Sorting trace points...  [0.916s]
Computing alignments...  [30.244s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.15s]
Computing alignments...  [30.337s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.042s]
Computing alignments...  [30.501s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.142s]
Computing alignments...  [29.776s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0s]
 [499.598s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [33.103s]
Masking reference...  [31.784s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.351s]
Allocating buffers...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [9.956s]
Building query seed array...  [1.93s]
Computing hash join...  [5.009s]
Masking low complexity seeds...  [0.195s]
Searching alignments...  [72.156s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.496s]
Building query seed array...  [2.279s]
Computing hash join...  [4.949s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [45.978s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.696s]
Building query seed array...  [2.368s]
Computing hash join...  [4.961s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [41.314s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.869s]
Building query seed array...  [1.867s]
Computing hash join...  [5.022s]
Masking low complexity seeds...  [0.2s]
Searching alignments...  [37.523s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.274s]
Building query seed array...  [1.784s]
Computing hash join...  [4.803s]
Masking low complexity seeds...  [0.186s]
Searching alignments...  [36.947s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.324s]
Building query seed array...  [2.019s]
Computing hash join...  [4.726s]
Masking low complexity seeds...  [0.189s]
Searching alignments...  [30.219s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.324s]
Building query seed array...  [2.23s]
Computing hash join...  [4.816s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [32.061s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.35s]
Building query seed array...  [1.75s]
Computing hash join...  [4.788s]
Masking low complexity seeds...  [0.195s]
Searching alignments...  [27.763s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.14s]
Clearing query masking...  [1.493s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [5.949s]
Sorting trace points...  [1.154s]
Computing alignments...  [29.811s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.059s]
Sorting trace points...  [0.894s]
Computing alignments...  [29.758s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.156s]
Computing alignments...  [30.082s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.134s]
Sorting trace points...  [1.124s]
Computing alignments...  [29.686s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.127s]
Sorting trace points...  [1.143s]
Computing alignments...  [29.725s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.079s]
Sorting trace points...  [2.138s]
Computing alignments...  [57.786s]
Deallocating buffers...  [0.034s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.021s]
Computing alignments...  [28.815s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.002s]
Computing alignments...  [29.17s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.132s]
Computing alignments...  [29.869s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.069s]
Computing alignments...  [29.973s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.145s]
Computing alignments...  [29.976s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.047s]
Computing alignments...  [30.117s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.152s]
Computing alignments...  [30.327s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.42s]
Sorting trace points...  [1.179s]
Computing alignments...  [30.39s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
Sorting trace points...  [1.077s]
Computing alignments...  [29.794s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [500.284s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [30.493s]
Masking reference...  [30.85s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.793s]
Allocating buffers...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.042s]
Building query seed array...  [1.917s]
Computing hash join...  [4.936s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [70.842s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.591s]
Building query seed array...  [2.203s]
Computing hash join...  [4.945s]
Masking low complexity seeds...  [0.198s]
Searching alignments...  [47.115s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.193s]
Building query seed array...  [2.335s]
Computing hash join...  [4.873s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [40.519s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.3s]
Building query seed array...  [1.907s]
Computing hash join...  [4.944s]
Masking low complexity seeds...  [0.2s]
Searching alignments...  [35.937s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.142s]
Building query seed array...  [1.722s]
Computing hash join...  [4.713s]
Masking low complexity seeds...  [0.194s]
Searching alignments...  [36.781s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.029s]
Building query seed array...  [2.006s]
Computing hash join...  [4.74s]
Masking low complexity seeds...  [0.19s]
Searching alignments...  [29.356s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.299s]
Building query seed array...  [2.127s]
Computing hash join...  [4.796s]
Masking low complexity seeds...  [0.192s]
Searching alignments...  [31.275s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.958s]
Building query seed array...  [1.696s]
Computing hash join...  [4.744s]
Masking low complexity seeds...  [0.195s]
Searching alignments...  [27.784s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.131s]
Clearing query masking...  [1.482s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [5.886s]
Sorting trace points...  [1.158s]
Computing alignments...  [30.023s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.102s]
Sorting trace points...  [1.11s]
Computing alignments...  [29.914s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.143s]
Computing alignments...  [30.092s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.084s]
Computing alignments...  [29.752s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.134s]
Sorting trace points...  [1.153s]
Computing alignments...  [29.814s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.055s]
Sorting trace points...  [2.208s]
Computing alignments...  [58.046s]
Deallocating buffers...  [0.035s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.09s]
Computing alignments...  [28.961s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.104s]
Computing alignments...  [29.38s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.158s]
Computing alignments...  [30.116s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.106s]
Computing alignments...  [30.071s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.09s]
Sorting trace points...  [1.119s]
Computing alignments...  [30.226s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.075s]
Sorting trace points...  [0.842s]
Computing alignments...  [30.392s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.13s]
Computing alignments...  [30.499s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.181s]
Computing alignments...  [30.621s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.107s]
Computing alignments...  [30.019s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [502.781s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.917s]
Masking reference...  [32.157s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.092s]
Allocating buffers...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.436s]
Building query seed array...  [1.899s]
Computing hash join...  [5.102s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [71.47s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.703s]
Building query seed array...  [2.235s]
Computing hash join...  [4.949s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [44.137s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.53s]
Building query seed array...  [2.382s]
Computing hash join...  [4.945s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [39.88s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.137s]
Building query seed array...  [1.926s]
Computing hash join...  [4.929s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [35.81s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.182s]
Building query seed array...  [1.787s]
Computing hash join...  [4.812s]
Masking low complexity seeds...  [0.2s]
Searching alignments...  [35.792s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.196s]
Building query seed array...  [2.054s]
Computing hash join...  [4.902s]
Masking low complexity seeds...  [0.191s]
Searching alignments...  [29.438s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.881s]
Building query seed array...  [2.095s]
Computing hash join...  [4.816s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [31.736s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.902s]
Building query seed array...  [1.687s]
Computing hash join...  [4.814s]
Masking low complexity seeds...  [0.188s]
Searching alignments...  [28.163s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.13s]
Clearing query masking...  [1.536s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [5.941s]
Sorting trace points...  [1.193s]
Computing alignments...  [29.841s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.067s]
Sorting trace points...  [0.89s]
Computing alignments...  [29.731s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.143s]
Computing alignments...  [29.868s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.082s]
Computing alignments...  [29.547s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.126s]
Sorting trace points...  [1.077s]
Computing alignments...  [29.64s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.062s]
Sorting trace points...  [2.21s]
Computing alignments...  [57.456s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.07s]
Computing alignments...  [28.628s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.11s]
Computing alignments...  [29.118s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.108s]
Computing alignments...  [29.702s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.087s]
Computing alignments...  [29.819s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.112s]
Computing alignments...  [29.847s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.083s]
Sorting trace points...  [0.959s]
Computing alignments...  [30.098s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.04s]
Sorting trace points...  [1.089s]
Computing alignments...  [30.245s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.115s]
Computing alignments...  [30.374s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.125s]
Computing alignments...  [29.767s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [498.103s]
Deallocating reference...  [0.073s]
Loading reference sequences...  [29.587s]
Masking reference...  [30.825s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.344s]
Allocating buffers...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.295s]
Building query seed array...  [1.9s]
Computing hash join...  [4.937s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [70.723s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.32s]
Building query seed array...  [2.185s]
Computing hash join...  [5.069s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [44.745s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.079s]
Building query seed array...  [2.372s]
Computing hash join...  [4.975s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [39.611s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.033s]
Building query seed array...  [1.982s]
Computing hash join...  [5.04s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [36.303s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.066s]
Building query seed array...  [1.742s]
Computing hash join...  [4.695s]
Masking low complexity seeds...  [0.198s]
Searching alignments...  [37.157s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.245s]
Building query seed array...  [2.015s]
Computing hash join...  [4.772s]
Masking low complexity seeds...  [0.19s]
Searching alignments...  [30.137s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.126s]
Building query seed array...  [2.114s]
Computing hash join...  [4.793s]
Masking low complexity seeds...  [0.198s]
Searching alignments...  [30.951s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.992s]
Building query seed array...  [1.699s]
Computing hash join...  [4.874s]
Masking low complexity seeds...  [0.191s]
Searching alignments...  [26.639s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.121s]
Clearing query masking...  [1.43s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.045s]
Sorting trace points...  [1.173s]
Computing alignments...  [29.471s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.066s]
Sorting trace points...  [0.922s]
Computing alignments...  [29.425s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.073s]
Sorting trace points...  [0.923s]
Computing alignments...  [29.674s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.157s]
Sorting trace points...  [1.099s]
Computing alignments...  [29.797s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.122s]
Sorting trace points...  [1.82s]
Computing alignments...  [57.523s]
Deallocating buffers...  [0.036s]
Loading trace points...  [0.063s]
Sorting trace points...  [2.19s]
Computing alignments...  [57.161s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.094s]
Sorting trace points...  [1.09s]
Computing alignments...  [29.07s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.086s]
Computing alignments...  [29.787s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.146s]
Computing alignments...  [29.823s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.092s]
Computing alignments...  [29.737s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.959s]
Computing alignments...  [30.041s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.145s]
Computing alignments...  [30.08s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.244s]
Sorting trace points...  [1.157s]
Computing alignments...  [30.205s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.078s]
Computing alignments...  [29.535s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [496.702s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.874s]
Masking reference...  [32.114s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.074s]
Allocating buffers...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [9.903s]
Building query seed array...  [1.884s]
Computing hash join...  [4.992s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [73.052s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.568s]
Building query seed array...  [2.164s]
Computing hash join...  [4.95s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [46.231s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.041s]
Building query seed array...  [2.362s]
Computing hash join...  [4.895s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [41.477s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.292s]
Building query seed array...  [1.923s]
Computing hash join...  [4.987s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [36.811s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.945s]
Building query seed array...  [1.764s]
Computing hash join...  [4.792s]
Masking low complexity seeds...  [0.192s]
Searching alignments...  [37.14s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.931s]
Building query seed array...  [2.037s]
Computing hash join...  [4.809s]
Masking low complexity seeds...  [0.19s]
Searching alignments...  [29.254s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.606s]
Building query seed array...  [2.117s]
Computing hash join...  [4.756s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [31.675s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.919s]
Building query seed array...  [1.691s]
Computing hash join...  [4.762s]
Masking low complexity seeds...  [0.189s]
Searching alignments...  [27.334s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.12s]
Clearing query masking...  [1.504s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [5.993s]
Sorting trace points...  [1.149s]
Computing alignments...  [29.818s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.009s]
Computing alignments...  [29.712s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.112s]
Computing alignments...  [29.919s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.126s]
Computing alignments...  [29.68s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.128s]
Sorting trace points...  [0.957s]
Computing alignments...  [29.829s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.073s]
Sorting trace points...  [2.023s]
Computing alignments...  [57.667s]
Deallocating buffers...  [0.034s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.071s]
Computing alignments...  [28.808s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.067s]
Computing alignments...  [29.246s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.086s]
Computing alignments...  [30.005s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.061s]
Sorting trace points...  [0.911s]
Computing alignments...  [30.045s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.063s]
Sorting trace points...  [0.858s]
Computing alignments...  [30.164s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.047s]
Computing alignments...  [30.379s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.167s]
Computing alignments...  [30.406s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.142s]
Computing alignments...  [30.536s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [0.963s]
Computing alignments...  [29.915s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
 [499.997s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.833s]
Masking reference...  [32.183s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.376s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.355s]
Building query seed array...  [1.853s]
Computing hash join...  [4.946s]
Masking low complexity seeds...  [0.199s]
Searching alignments...  [72.495s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.61s]
Building query seed array...  [2.192s]
Computing hash join...  [4.954s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [45.74s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.275s]
Building query seed array...  [2.361s]
Computing hash join...  [4.892s]
Masking low complexity seeds...  [0.193s]
Searching alignments...  [39.159s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.864s]
Building query seed array...  [1.873s]
Computing hash join...  [5s]
Masking low complexity seeds...  [0.2s]
Searching alignments...  [35.658s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.799s]
Building query seed array...  [1.796s]
Computing hash join...  [4.804s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [37.032s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.354s]
Building query seed array...  [2.018s]
Computing hash join...  [4.774s]
Masking low complexity seeds...  [0.189s]
Searching alignments...  [29.29s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.355s]
Building query seed array...  [2.11s]
Computing hash join...  [4.793s]
Masking low complexity seeds...  [0.199s]
Searching alignments...  [31.673s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.061s]
Building query seed array...  [1.697s]
Computing hash join...  [4.78s]
Masking low complexity seeds...  [0.192s]
Searching alignments...  [27.279s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.53s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.129s]
Sorting trace points...  [1.097s]
Computing alignments...  [29.811s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.088s]
Computing alignments...  [29.647s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.053s]
Sorting trace points...  [0.965s]
Computing alignments...  [30.026s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.119s]
Computing alignments...  [29.601s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.114s]
Sorting trace points...  [1.146s]
Computing alignments...  [29.673s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.061s]
Sorting trace points...  [2.04s]
Computing alignments...  [57.505s]
Deallocating buffers...  [0.039s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.113s]
Computing alignments...  [28.741s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.101s]
Computing alignments...  [29.175s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.024s]
Computing alignments...  [29.889s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.075s]
Computing alignments...  [29.954s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.109s]
Computing alignments...  [29.958s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.101s]
Sorting trace points...  [0.986s]
Computing alignments...  [30.144s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.109s]
Computing alignments...  [30.32s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.119s]
Computing alignments...  [30.427s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.166s]
Computing alignments...  [29.805s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0s]
 [499.284s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [31.94s]
Masking reference...  [31.92s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [31.919s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.461s]
Building query seed array...  [1.981s]
Computing hash join...  [4.992s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [71.092s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.489s]
Building query seed array...  [2.247s]
Computing hash join...  [5.004s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [47.246s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.371s]
Building query seed array...  [2.355s]
Computing hash join...  [5.01s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [39.828s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.756s]
Building query seed array...  [1.874s]
Computing hash join...  [4.957s]
Masking low complexity seeds...  [0.196s]
Searching alignments...  [35.601s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.916s]
Building query seed array...  [1.75s]
Computing hash join...  [4.869s]
Masking low complexity seeds...  [0.194s]
Searching alignments...  [36.931s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.366s]
Building query seed array...  [1.998s]
Computing hash join...  [4.735s]
Masking low complexity seeds...  [0.187s]
Searching alignments...  [29.98s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.399s]
Building query seed array...  [2.169s]
Computing hash join...  [4.784s]
Masking low complexity seeds...  [0.183s]
Searching alignments...  [31.872s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.191s]
Building query seed array...  [1.763s]
Computing hash join...  [4.847s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [27.576s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.131s]
Clearing query masking...  [1.487s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [5.994s]
Sorting trace points...  [1.102s]
Computing alignments...  [29.933s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.061s]
Sorting trace points...  [0.885s]
Computing alignments...  [29.763s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.002s]
Sorting trace points...  [1.137s]
Computing alignments...  [30.006s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.078s]
Computing alignments...  [29.805s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.12s]
Sorting trace points...  [1.09s]
Computing alignments...  [29.747s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.789s]
Computing alignments...  [57.68s]
Deallocating buffers...  [0.037s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.047s]
Computing alignments...  [28.71s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.045s]
Sorting trace points...  [0.901s]
Computing alignments...  [29.253s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.058s]
Sorting trace points...  [0.925s]
Computing alignments...  [29.969s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.103s]
Computing alignments...  [29.902s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.123s]
Computing alignments...  [30.049s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.075s]
Sorting trace points...  [0.994s]
Computing alignments...  [30.277s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.033s]
Sorting trace points...  [1.057s]
Computing alignments...  [30.379s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.179s]
Computing alignments...  [30.383s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [0.993s]
Computing alignments...  [29.747s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [499.156s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.688s]
Masking reference...  [30.842s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.469s]
Allocating buffers...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.09s]
Building query seed array...  [1.982s]
Computing hash join...  [4.962s]
Masking low complexity seeds...  [0.199s]
Searching alignments...  [73.32s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.609s]
Building query seed array...  [2.275s]
Computing hash join...  [4.953s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [45.81s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.518s]
Building query seed array...  [2.331s]
Computing hash join...  [5.047s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [40.035s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.857s]
Building query seed array...  [1.889s]
Computing hash join...  [4.952s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [37.744s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.795s]
Building query seed array...  [1.711s]
Computing hash join...  [4.845s]
Masking low complexity seeds...  [0.186s]
Searching alignments...  [37.546s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.535s]
Building query seed array...  [2.024s]
Computing hash join...  [4.807s]
Masking low complexity seeds...  [0.189s]
Searching alignments...  [29.578s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.291s]
Building query seed array...  [2.085s]
Computing hash join...  [4.779s]
Masking low complexity seeds...  [0.192s]
Searching alignments...  [31.537s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.217s]
Building query seed array...  [1.777s]
Computing hash join...  [4.827s]
Masking low complexity seeds...  [0.196s]
Searching alignments...  [27.634s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.489s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.073s]
Sorting trace points...  [1.166s]
Computing alignments...  [29.663s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.099s]
Computing alignments...  [29.594s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.127s]
Computing alignments...  [29.912s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.181s]
Sorting trace points...  [0.961s]
Computing alignments...  [29.85s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.137s]
Sorting trace points...  [1.772s]
Computing alignments...  [57.971s]
Deallocating buffers...  [0.036s]
Loading trace points...  [0.067s]
Sorting trace points...  [2.192s]
Computing alignments...  [57.322s]
Deallocating buffers...  [0.032s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.091s]
Computing alignments...  [29.087s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.056s]
Sorting trace points...  [0.962s]
Computing alignments...  [29.803s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.145s]
Computing alignments...  [29.814s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.114s]
Sorting trace points...  [1.11s]
Computing alignments...  [29.958s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.126s]
Computing alignments...  [30.034s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.148s]
Computing alignments...  [30.17s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.938s]
Sorting trace points...  [1.158s]
Computing alignments...  [30.248s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.128s]
Computing alignments...  [29.666s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0s]
 [498.551s]
Deallocating reference...  [0.057s]
Loading reference sequences...  [29.727s]
Masking reference...  [30.815s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.67s]
Allocating buffers...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.282s]
Building query seed array...  [1.95s]
Computing hash join...  [4.927s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [70.332s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.223s]
Building query seed array...  [2.236s]
Computing hash join...  [4.988s]
Masking low complexity seeds...  [0.199s]
Searching alignments...  [44.933s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.597s]
Building query seed array...  [2.365s]
Computing hash join...  [4.927s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [41.37s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.927s]
Building query seed array...  [1.899s]
Computing hash join...  [4.991s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [35.388s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.83s]
Building query seed array...  [1.77s]
Computing hash join...  [4.701s]
Masking low complexity seeds...  [0.193s]
Searching alignments...  [35.717s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.384s]
Building query seed array...  [2.04s]
Computing hash join...  [4.793s]
Masking low complexity seeds...  [0.188s]
Searching alignments...  [29.471s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.994s]
Building query seed array...  [2.146s]
Computing hash join...  [4.792s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [31.351s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.769s]
Building query seed array...  [1.756s]
Computing hash join...  [4.836s]
Masking low complexity seeds...  [0.189s]
Searching alignments...  [27.11s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.133s]
Clearing query masking...  [1.507s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [5.867s]
Sorting trace points...  [1.146s]
Computing alignments...  [29.699s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.86s]
Sorting trace points...  [1.135s]
Computing alignments...  [29.641s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.084s]
Sorting trace points...  [1.083s]
Computing alignments...  [29.889s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.552s]
Sorting trace points...  [0.879s]
Computing alignments...  [29.933s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.179s]
Sorting trace points...  [1.774s]
Computing alignments...  [58.193s]
Deallocating buffers...  [0.034s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.591s]
Computing alignments...  [57.563s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.092s]
Computing alignments...  [29.088s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.071s]
Sorting trace points...  [0.863s]
Computing alignments...  [29.973s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.048s]
Sorting trace points...  [0.967s]
Computing alignments...  [29.896s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.079s]
Computing alignments...  [30.014s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.077s]
Sorting trace points...  [0.912s]
Computing alignments...  [30.688s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.002s]
Sorting trace points...  [1.078s]
Computing alignments...  [30.381s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.052s]
Sorting trace points...  [0.975s]
Computing alignments...  [30.442s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.132s]
Computing alignments...  [29.775s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0s]
 [499.208s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [29.462s]
Masking reference...  [32.086s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [31.892s]
Allocating buffers...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.071s]
Building query seed array...  [1.926s]
Computing hash join...  [5.254s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [72.62s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.385s]
Building query seed array...  [2.219s]
Computing hash join...  [4.969s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [44.111s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.463s]
Building query seed array...  [2.312s]
Computing hash join...  [4.96s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [39.561s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.733s]
Building query seed array...  [1.839s]
Computing hash join...  [4.971s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [36.566s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.091s]
Building query seed array...  [1.799s]
Computing hash join...  [4.768s]
Masking low complexity seeds...  [0.195s]
Searching alignments...  [36.379s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.436s]
Building query seed array...  [2.07s]
Computing hash join...  [4.997s]
Masking low complexity seeds...  [0.193s]
Searching alignments...  [29.948s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.821s]
Building query seed array...  [2.097s]
Computing hash join...  [4.799s]
Masking low complexity seeds...  [0.197s]
Searching alignments...  [32.532s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.159s]
Building query seed array...  [1.689s]
Computing hash join...  [4.878s]
Masking low complexity seeds...  [0.191s]
Searching alignments...  [27.132s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.12s]
Clearing query masking...  [1.416s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.081s]
Sorting trace points...  [1.084s]
Computing alignments...  [29.705s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.114s]
Computing alignments...  [29.513s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.099s]
Computing alignments...  [29.797s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.109s]
Computing alignments...  [29.534s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.179s]
Sorting trace points...  [0.854s]
Computing alignments...  [29.679s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.061s]
Sorting trace points...  [2.196s]
Computing alignments...  [57.613s]
Deallocating buffers...  [0.034s]
Loading trace points...  [0.063s]
Sorting trace points...  [0.829s]
Computing alignments...  [28.696s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.067s]
Computing alignments...  [29.101s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.089s]
Computing alignments...  [29.899s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.033s]
Computing alignments...  [29.841s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.153s]
Computing alignments...  [30.06s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.066s]
Sorting trace points...  [0.927s]
Computing alignments...  [30.22s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.04s]
Sorting trace points...  [1.161s]
Computing alignments...  [30.25s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.161s]
Computing alignments...  [30.344s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.146s]
Computing alignments...  [29.708s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [498.269s]
Deallocating reference...  [0.067s]
Loading reference sequences...  [29.54s]
Masking reference...  [32.051s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.138s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.415s]
Building query seed array...  [1.924s]
Computing hash join...  [4.933s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [74.238s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.386s]
Building query seed array...  [2.247s]
Computing hash join...  [4.946s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [45.661s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.107s]
Building query seed array...  [2.345s]
Computing hash join...  [4.897s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [40.793s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.375s]
Building query seed array...  [1.929s]
Computing hash join...  [4.982s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [38.291s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.107s]
Building query seed array...  [1.805s]
Computing hash join...  [4.784s]
Masking low complexity seeds...  [0.193s]
Searching alignments...  [36.964s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.356s]
Building query seed array...  [2.024s]
Computing hash join...  [4.897s]
Masking low complexity seeds...  [0.198s]
Searching alignments...  [29.723s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.392s]
Building query seed array...  [2.085s]
Computing hash join...  [4.711s]
Masking low complexity seeds...  [0.199s]
Searching alignments...  [31.421s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.193s]
Building query seed array...  [1.766s]
Computing hash join...  [4.907s]
Masking low complexity seeds...  [0.188s]
Searching alignments...  [27.25s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.462s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [5.883s]
Sorting trace points...  [1.152s]
Computing alignments...  [29.769s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.094s]
Sorting trace points...  [1.112s]
Computing alignments...  [29.696s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.136s]
Sorting trace points...  [0.884s]
Computing alignments...  [29.926s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.134s]
Sorting trace points...  [1.043s]
Computing alignments...  [29.983s]
Deallocating buffers...  [0.02s]
Loading trace points...  [1.198s]
Sorting trace points...  [2.275s]
Computing alignments...  [58.078s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.719s]
Computing alignments...  [57.842s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.09s]
Computing alignments...  [29.211s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.099s]
Computing alignments...  [30.04s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.134s]
Computing alignments...  [29.959s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.034s]
Computing alignments...  [30.072s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.167s]
Computing alignments...  [30.243s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.157s]
Computing alignments...  [30.312s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.074s]
Computing alignments...  [30.501s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.129s]
Computing alignments...  [29.901s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0s]
 [500.829s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [23.854s]
Masking reference...  [26.028s]
Initializing dictionary...  [0.062s]
Initializing temporary storage...  [0.006s]
Building reference histograms...  [26.24s]
Allocating buffers...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.615s]
Building query seed array...  [1.936s]
Computing hash join...  [4.132s]
Masking low complexity seeds...  [0.193s]
Searching alignments...  [58.408s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [10.424s]
Building query seed array...  [2.217s]
Computing hash join...  [4.171s]
Masking low complexity seeds...  [0.197s]
Searching alignments...  [37.64s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [10.756s]
Building query seed array...  [2.424s]
Computing hash join...  [4.088s]
Masking low complexity seeds...  [0.192s]
Searching alignments...  [33.192s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [7.917s]
Building query seed array...  [1.93s]
Computing hash join...  [4.094s]
Masking low complexity seeds...  [0.2s]
Searching alignments...  [29.958s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [8.292s]
Building query seed array...  [1.749s]
Computing hash join...  [3.981s]
Masking low complexity seeds...  [0.195s]
Searching alignments...  [29.394s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [9.726s]
Building query seed array...  [2.028s]
Computing hash join...  [3.954s]
Masking low complexity seeds...  [0.193s]
Searching alignments...  [24.151s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [10.919s]
Building query seed array...  [2.087s]
Computing hash join...  [3.99s]
Masking low complexity seeds...  [0.186s]
Searching alignments...  [25.909s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [8.361s]
Building query seed array...  [1.748s]
Computing hash join...  [3.932s]
Masking low complexity seeds...  [0.179s]
Searching alignments...  [22.386s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.111s]
Clearing query masking...  [1.436s]
Opening temporary output file...  [0.014s]
Computing alignments... Loading trace points...  [10.066s]
Sorting trace points...  [1.895s]
Computing alignments...  [47.549s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.137s]
Sorting trace points...  [1.532s]
Computing alignments...  [47.478s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.113s]
Sorting trace points...  [1.791s]
Computing alignments...  [46.328s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.135s]
Sorting trace points...  [1.619s]
Computing alignments...  [46.235s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.131s]
Sorting trace points...  [1.481s]
Computing alignments...  [47.177s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.116s]
Sorting trace points...  [1.868s]
Computing alignments...  [47.733s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.136s]
Sorting trace points...  [1.831s]
Computing alignments...  [48.152s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.819s]
Computing alignments...  [47.67s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0s]
 [403.389s]
Deallocating reference...  [0.05s]
Loading reference sequences...  [0.102s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [1898.7s]
 [1898.7s]
Deallocating queries...  [0.046s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [3.669s]
 [4.716s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 16708.8s
Reported 2485777139 pairwise alignments, 2485777139 HSPs.
12148909 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C24_R1.fastp-trim.20230215.fq.gz complete: C24_R1.blastx.meganized.daa

Now MEGANizing C24_R1.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: C24_R1.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 100% (240.5s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.3s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (4,617.9s)
Total reads:       12,148,909
With hits:          12,148,909 
Alignments:      2,474,797,245
Assig. Taxonomy:    11,538,182
Assig. SEED:            98,685
Assig. EGGNOG:          48,081
Assig. GTDB:           399,395
Assig. EC:           1,971,697
Assig. INTERPRO2GO:  1,119,454
MinSupport set to: 6074
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.3s)
Min-supp. changes:       4,195
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (10.1s)
Min-supp. changes:       3,062
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (39.4s)
Binning reads Syncing
100% (0.4s)
Class. Taxonomy:           107
Class. SEED:               532
Class. EGGNOG:           1,907
Class. GTDB:                22
Class. EC:               2,430
Class. INTERPRO2GO:      7,892
Total time:  4,918s
Peak memory: 33.2 of 195.3G
MEGANization of C24_R1.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C24_R2.fastp-trim.20230215.fq.gz...
6f38b712a376382cc1be6d309de4a6cf  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C24_R2.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C24_R2.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.332s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.747s]
Opening the output file...  [0s]
Loading query sequences...  [69.865s]
Masking queries...  [17.261s]
Algorithm: Double-indexed
Building query histograms...  [16.761s]
Loading reference sequences...  [29.477s]
Masking reference...  [31.914s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.696s]
Allocating buffers...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.183s]
Building query seed array...  [1.892s]
Computing hash join...  [5.35s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [70.062s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.506s]
Building query seed array...  [2.228s]
Computing hash join...  [5.083s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [47.814s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.274s]
Building query seed array...  [2.389s]
Computing hash join...  [5.096s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [41.088s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.025s]
Building query seed array...  [1.916s]
Computing hash join...  [5.239s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [36.701s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.707s]
Building query seed array...  [1.732s]
Computing hash join...  [5s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [40.338s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.034s]
Building query seed array...  [2.019s]
Computing hash join...  [4.847s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [30.652s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.048s]
Building query seed array...  [2.115s]
Computing hash join...  [4.939s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [32.694s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.04s]
Building query seed array...  [1.799s]
Computing hash join...  [4.854s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [27.578s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.121s]
Clearing query masking...  [1.52s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [11.497s]
Sorting trace points...  [2.249s]
Computing alignments...  [57.296s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0.083s]
Sorting trace points...  [2.194s]
Computing alignments...  [57.652s]
Deallocating buffers...  [0.037s]
Loading trace points...  [0.057s]
Sorting trace points...  [0.891s]
Computing alignments...  [30.041s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.132s]
Sorting trace points...  [0.994s]
Computing alignments...  [30.224s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.045s]
Sorting trace points...  [2.574s]
Computing alignments...  [57.677s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.051s]
Sorting trace points...  [0.878s]
Computing alignments...  [29.249s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.15s]
Computing alignments...  [30.458s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.569s]
Sorting trace points...  [1.15s]
Computing alignments...  [30.659s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.076s]
Sorting trace points...  [0.931s]
Computing alignments...  [30.453s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.144s]
Computing alignments...  [30.876s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.153s]
Computing alignments...  [30.88s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.173s]
Computing alignments...  [31.069s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.126s]
Computing alignments...  [30.744s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [508.077s]
Deallocating reference...  [0.068s]
Loading reference sequences...  [29.706s]
Masking reference...  [30.89s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.275s]
Allocating buffers...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.314s]
Building query seed array...  [1.915s]
Computing hash join...  [5.167s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [67.747s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.358s]
Building query seed array...  [2.273s]
Computing hash join...  [5.138s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [45.429s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.733s]
Building query seed array...  [2.339s]
Computing hash join...  [5.005s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [40.923s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.234s]
Building query seed array...  [1.907s]
Computing hash join...  [5.069s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [36.285s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.115s]
Building query seed array...  [1.771s]
Computing hash join...  [4.821s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [39.253s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.859s]
Building query seed array...  [2.034s]
Computing hash join...  [4.833s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [30.53s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.683s]
Building query seed array...  [2.131s]
Computing hash join...  [4.901s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [31.808s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.291s]
Building query seed array...  [1.752s]
Computing hash join...  [4.895s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [27.584s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.121s]
Clearing query masking...  [1.462s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [10.751s]
Sorting trace points...  [2.297s]
Computing alignments...  [57.256s]
Deallocating buffers...  [0.032s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.767s]
Computing alignments...  [57.513s]
Deallocating buffers...  [0.042s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.106s]
Computing alignments...  [29.874s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.16s]
Computing alignments...  [30.104s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.927s]
Computing alignments...  [57.537s]
Deallocating buffers...  [0.042s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.06s]
Computing alignments...  [29.305s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.111s]
Sorting trace points...  [1.112s]
Computing alignments...  [30.41s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.069s]
Sorting trace points...  [0.904s]
Computing alignments...  [30.553s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.148s]
Computing alignments...  [30.356s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.093s]
Sorting trace points...  [1.17s]
Computing alignments...  [30.92s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.133s]
Computing alignments...  [31.271s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.221s]
Computing alignments...  [31.131s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
Sorting trace points...  [1.169s]
Computing alignments...  [30.795s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [506.161s]
Deallocating reference...  [0.063s]
Loading reference sequences...  [33.582s]
Masking reference...  [31.092s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.011s]
Building reference histograms...  [32.44s]
Allocating buffers...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.513s]
Building query seed array...  [1.963s]
Computing hash join...  [5.082s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [73.829s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.469s]
Building query seed array...  [2.308s]
Computing hash join...  [5.046s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [45.961s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.985s]
Building query seed array...  [2.54s]
Computing hash join...  [5.166s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [41.382s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.85s]
Building query seed array...  [1.878s]
Computing hash join...  [5.06s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [37.172s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.041s]
Building query seed array...  [1.727s]
Computing hash join...  [4.828s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [39.704s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.068s]
Building query seed array...  [2.044s]
Computing hash join...  [4.977s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [30.369s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.24s]
Building query seed array...  [2.14s]
Computing hash join...  [4.924s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [32.988s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.788s]
Building query seed array...  [1.735s]
Computing hash join...  [4.837s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [28.609s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.137s]
Clearing query masking...  [1.587s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [11.702s]
Sorting trace points...  [2.285s]
Computing alignments...  [57.212s]
Deallocating buffers...  [0.034s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.796s]
Computing alignments...  [57.521s]
Deallocating buffers...  [0.043s]
Loading trace points...  [0.066s]
Sorting trace points...  [0.92s]
Computing alignments...  [29.922s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.086s]
Sorting trace points...  [0.942s]
Computing alignments...  [30.191s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.086s]
Sorting trace points...  [2.058s]
Computing alignments...  [57.748s]
Deallocating buffers...  [0.045s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.132s]
Computing alignments...  [29.183s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.148s]
Computing alignments...  [30.389s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.131s]
Computing alignments...  [30.473s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.095s]
Sorting trace points...  [1.096s]
Computing alignments...  [30.376s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.1s]
Computing alignments...  [30.84s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.138s]
Computing alignments...  [30.846s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.179s]
Computing alignments...  [30.976s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [0.979s]
Computing alignments...  [30.691s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [506.142s]
Deallocating reference...  [0.073s]
Loading reference sequences...  [31.781s]
Masking reference...  [31.131s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.3s]
Allocating buffers...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [9.95s]
Building query seed array...  [1.946s]
Computing hash join...  [5.06s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [69.591s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.998s]
Building query seed array...  [2.275s]
Computing hash join...  [5.109s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [44.983s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.764s]
Building query seed array...  [2.297s]
Computing hash join...  [5.266s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [41.901s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.088s]
Building query seed array...  [1.918s]
Computing hash join...  [5.047s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [37.022s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.311s]
Building query seed array...  [1.818s]
Computing hash join...  [4.965s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [39.077s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.627s]
Building query seed array...  [2.037s]
Computing hash join...  [4.9s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [30.365s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.011s]
Building query seed array...  [2.13s]
Computing hash join...  [4.923s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [32.007s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.229s]
Building query seed array...  [1.664s]
Computing hash join...  [4.969s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [28.269s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.13s]
Clearing query masking...  [1.478s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [10.877s]
Sorting trace points...  [2.229s]
Computing alignments...  [57.631s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.087s]
Sorting trace points...  [2.157s]
Computing alignments...  [57.645s]
Deallocating buffers...  [0.037s]
Loading trace points...  [0.056s]
Sorting trace points...  [0.899s]
Computing alignments...  [29.967s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.125s]
Sorting trace points...  [1.134s]
Computing alignments...  [30.181s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.824s]
Computing alignments...  [57.659s]
Deallocating buffers...  [0.035s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.12s]
Computing alignments...  [29.359s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.042s]
Sorting trace points...  [1.162s]
Computing alignments...  [30.484s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.001s]
Sorting trace points...  [0.887s]
Computing alignments...  [30.558s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.151s]
Sorting trace points...  [1.013s]
Computing alignments...  [30.499s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.188s]
Computing alignments...  [30.981s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.119s]
Computing alignments...  [30.952s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.208s]
Computing alignments...  [31.176s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [0.945s]
Computing alignments...  [30.876s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [506.889s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [34.517s]
Masking reference...  [30.897s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.137s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.334s]
Building query seed array...  [1.948s]
Computing hash join...  [5.115s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [69.005s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.65s]
Building query seed array...  [2.274s]
Computing hash join...  [5.032s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [45.414s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.418s]
Building query seed array...  [2.441s]
Computing hash join...  [5.082s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [41.449s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.849s]
Building query seed array...  [2.041s]
Computing hash join...  [5.026s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [37.688s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.049s]
Building query seed array...  [1.771s]
Computing hash join...  [4.932s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [38.587s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.243s]
Building query seed array...  [2.057s]
Computing hash join...  [4.885s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [30.404s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.303s]
Building query seed array...  [2.127s]
Computing hash join...  [4.911s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [33.36s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.591s]
Building query seed array...  [1.758s]
Computing hash join...  [4.932s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [28.386s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.525s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [11.501s]
Sorting trace points...  [2.228s]
Computing alignments...  [57.048s]
Deallocating buffers...  [0.034s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.787s]
Computing alignments...  [57.309s]
Deallocating buffers...  [0.042s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.008s]
Computing alignments...  [29.782s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.098s]
Sorting trace points...  [1.023s]
Computing alignments...  [30.05s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.096s]
Sorting trace points...  [2.145s]
Computing alignments...  [57.331s]
Deallocating buffers...  [0.035s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.103s]
Computing alignments...  [29.22s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.043s]
Sorting trace points...  [0.911s]
Computing alignments...  [30.304s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.117s]
Computing alignments...  [30.527s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.163s]
Computing alignments...  [30.34s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.158s]
Computing alignments...  [30.769s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.037s]
Sorting trace points...  [1.183s]
Computing alignments...  [30.87s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.326s]
Sorting trace points...  [0.975s]
Computing alignments...  [31.068s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [0.967s]
Computing alignments...  [30.69s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [504.872s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [33.332s]
Masking reference...  [31.263s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.756s]
Allocating buffers...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.39s]
Building query seed array...  [1.946s]
Computing hash join...  [5.118s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [67.332s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.18s]
Building query seed array...  [2.238s]
Computing hash join...  [5.087s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [45.776s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.721s]
Building query seed array...  [2.359s]
Computing hash join...  [5.067s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [39.551s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.861s]
Building query seed array...  [1.928s]
Computing hash join...  [5.01s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [36.177s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.021s]
Building query seed array...  [1.753s]
Computing hash join...  [4.884s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [37.763s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.253s]
Building query seed array...  [2.061s]
Computing hash join...  [4.936s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [30.356s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.135s]
Building query seed array...  [2.208s]
Computing hash join...  [4.885s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [30.736s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.062s]
Building query seed array...  [1.742s]
Computing hash join...  [4.949s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [27.722s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.14s]
Clearing query masking...  [1.49s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [11.146s]
Sorting trace points...  [2.165s]
Computing alignments...  [56.535s]
Deallocating buffers...  [0.034s]
Loading trace points...  [0.065s]
Sorting trace points...  [2.033s]
Computing alignments...  [56.618s]
Deallocating buffers...  [0.039s]
Loading trace points...  [0.055s]
Sorting trace points...  [0.984s]
Computing alignments...  [29.391s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.157s]
Sorting trace points...  [1.112s]
Computing alignments...  [29.656s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.708s]
Computing alignments...  [56.635s]
Deallocating buffers...  [0.034s]
Loading trace points...  [0.091s]
Sorting trace points...  [1.056s]
Computing alignments...  [28.861s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.114s]
Computing alignments...  [30.129s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.172s]
Computing alignments...  [30.177s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.132s]
Computing alignments...  [30.581s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.042s]
Sorting trace points...  [0.939s]
Computing alignments...  [30.525s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.13s]
Computing alignments...  [30.515s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.115s]
Computing alignments...  [30.68s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.138s]
Computing alignments...  [30.282s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [499.553s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [30.916s]
Masking reference...  [30.834s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.592s]
Allocating buffers...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.132s]
Building query seed array...  [1.907s]
Computing hash join...  [5.19s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [72.799s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.217s]
Building query seed array...  [2.288s]
Computing hash join...  [5.016s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [44.887s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.286s]
Building query seed array...  [2.424s]
Computing hash join...  [5.13s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [39.664s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.352s]
Building query seed array...  [1.933s]
Computing hash join...  [5.032s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [35.699s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.976s]
Building query seed array...  [1.733s]
Computing hash join...  [4.852s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [39.664s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.199s]
Building query seed array...  [2.051s]
Computing hash join...  [4.785s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [29.986s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.121s]
Building query seed array...  [2.153s]
Computing hash join...  [4.94s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [33.365s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.846s]
Building query seed array...  [1.74s]
Computing hash join...  [4.915s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [27.915s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.452s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [11.598s]
Sorting trace points...  [2.164s]
Computing alignments...  [57.2s]
Deallocating buffers...  [0.034s]
Loading trace points...  [0.069s]
Sorting trace points...  [2.218s]
Computing alignments...  [57.297s]
Deallocating buffers...  [0.036s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.043s]
Computing alignments...  [29.721s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.594s]
Sorting trace points...  [0.895s]
Computing alignments...  [30.004s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.052s]
Sorting trace points...  [2.289s]
Computing alignments...  [57.289s]
Deallocating buffers...  [0.034s]
Loading trace points...  [0.066s]
Sorting trace points...  [0.839s]
Computing alignments...  [29.229s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.804s]
Sorting trace points...  [1.181s]
Computing alignments...  [30.363s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.161s]
Computing alignments...  [30.479s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.118s]
Computing alignments...  [30.335s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.171s]
Computing alignments...  [30.718s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.141s]
Computing alignments...  [30.755s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.199s]
Computing alignments...  [30.991s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.14s]
Computing alignments...  [30.678s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
 [506.593s]
Deallocating reference...  [0.068s]
Loading reference sequences...  [29.634s]
Masking reference...  [30.833s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [33.225s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.37s]
Building query seed array...  [1.942s]
Computing hash join...  [5.154s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [71.48s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.309s]
Building query seed array...  [2.266s]
Computing hash join...  [4.99s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [44.242s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.176s]
Building query seed array...  [2.307s]
Computing hash join...  [5.071s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [39.678s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.9s]
Building query seed array...  [1.897s]
Computing hash join...  [5.087s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [35.157s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.709s]
Building query seed array...  [1.735s]
Computing hash join...  [4.896s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [37.929s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.33s]
Building query seed array...  [1.969s]
Computing hash join...  [4.807s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [30.851s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.251s]
Building query seed array...  [2.158s]
Computing hash join...  [4.862s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [33.788s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.775s]
Building query seed array...  [1.706s]
Computing hash join...  [4.844s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [28.462s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.492s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [11.719s]
Sorting trace points...  [2.304s]
Computing alignments...  [57.209s]
Deallocating buffers...  [0.034s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.959s]
Computing alignments...  [57.344s]
Deallocating buffers...  [0.04s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.065s]
Computing alignments...  [29.645s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.105s]
Sorting trace points...  [0.904s]
Computing alignments...  [29.953s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.744s]
Computing alignments...  [57.398s]
Deallocating buffers...  [0.037s]
Loading trace points...  [0.038s]
Sorting trace points...  [1.043s]
Computing alignments...  [29.117s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.185s]
Computing alignments...  [30.473s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.132s]
Computing alignments...  [30.633s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.013s]
Computing alignments...  [30.334s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.166s]
Computing alignments...  [30.712s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.929s]
Sorting trace points...  [1.177s]
Computing alignments...  [30.757s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.075s]
Sorting trace points...  [0.937s]
Computing alignments...  [30.98s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [0.988s]
Computing alignments...  [30.584s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [505.441s]
Deallocating reference...  [0.069s]
Loading reference sequences...  [29.522s]
Masking reference...  [32.128s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [31.873s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.42s]
Building query seed array...  [1.913s]
Computing hash join...  [5.109s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [72.052s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.575s]
Building query seed array...  [2.218s]
Computing hash join...  [5.122s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [45.528s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.745s]
Building query seed array...  [2.386s]
Computing hash join...  [5.063s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [40.194s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.954s]
Building query seed array...  [1.932s]
Computing hash join...  [5.072s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [35.572s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.034s]
Building query seed array...  [1.793s]
Computing hash join...  [4.944s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [39.761s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.379s]
Building query seed array...  [2.017s]
Computing hash join...  [4.838s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [30.957s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.381s]
Building query seed array...  [2.138s]
Computing hash join...  [4.875s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [32.391s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.792s]
Building query seed array...  [1.746s]
Computing hash join...  [4.821s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [28.222s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.135s]
Clearing query masking...  [1.462s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [11.539s]
Sorting trace points...  [2.283s]
Computing alignments...  [57.147s]
Deallocating buffers...  [0.035s]
Loading trace points...  [0.089s]
Sorting trace points...  [2.039s]
Computing alignments...  [57.281s]
Deallocating buffers...  [0.043s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.126s]
Computing alignments...  [29.692s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.003s]
Sorting trace points...  [1.149s]
Computing alignments...  [29.929s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.831s]
Computing alignments...  [57.401s]
Deallocating buffers...  [0.035s]
Loading trace points...  [0.039s]
Sorting trace points...  [1.128s]
Computing alignments...  [29.105s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.146s]
Computing alignments...  [30.328s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.023s]
Computing alignments...  [30.503s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.067s]
Sorting trace points...  [0.853s]
Computing alignments...  [30.295s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.145s]
Computing alignments...  [30.755s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.031s]
Computing alignments...  [30.722s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.098s]
Computing alignments...  [30.957s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.104s]
Computing alignments...  [30.59s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
 [504.198s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.767s]
Masking reference...  [30.832s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.895s]
Allocating buffers...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.084s]
Building query seed array...  [1.936s]
Computing hash join...  [5.118s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [71.674s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.269s]
Building query seed array...  [2.256s]
Computing hash join...  [5.103s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [46.266s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [12.917s]
Building query seed array...  [2.358s]
Computing hash join...  [5.242s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [41.053s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.233s]
Building query seed array...  [1.942s]
Computing hash join...  [5.018s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [37.212s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.295s]
Building query seed array...  [1.766s]
Computing hash join...  [4.957s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [41.241s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.5s]
Building query seed array...  [1.997s]
Computing hash join...  [4.867s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [30.826s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.922s]
Building query seed array...  [2.161s]
Computing hash join...  [4.89s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [34.339s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.034s]
Building query seed array...  [1.777s]
Computing hash join...  [4.793s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [28.896s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.162s]
Clearing query masking...  [1.649s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [11.572s]
Sorting trace points...  [2.256s]
Computing alignments...  [56.836s]
Deallocating buffers...  [0.034s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.863s]
Computing alignments...  [57.239s]
Deallocating buffers...  [0.039s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.147s]
Computing alignments...  [29.779s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.002s]
Sorting trace points...  [1.127s]
Computing alignments...  [30.096s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.066s]
Sorting trace points...  [2.184s]
Computing alignments...  [57.416s]
Deallocating buffers...  [0.039s]
Loading trace points...  [0.055s]
Sorting trace points...  [0.957s]
Computing alignments...  [29.232s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.025s]
Computing alignments...  [30.381s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.165s]
Computing alignments...  [30.466s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.071s]
Sorting trace points...  [0.873s]
Computing alignments...  [30.309s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.122s]
Computing alignments...  [30.692s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.037s]
Sorting trace points...  [1.145s]
Computing alignments...  [30.711s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.207s]
Computing alignments...  [30.888s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.124s]
Computing alignments...  [30.502s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [504.352s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.67s]
Masking reference...  [32.125s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [31.9s]
Allocating buffers...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.13s]
Building query seed array...  [1.959s]
Computing hash join...  [5.005s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [69.874s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.318s]
Building query seed array...  [2.284s]
Computing hash join...  [5.172s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [46.433s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.098s]
Building query seed array...  [2.35s]
Computing hash join...  [5.16s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [39.454s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.466s]
Building query seed array...  [1.895s]
Computing hash join...  [5.109s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [36.722s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.33s]
Building query seed array...  [1.705s]
Computing hash join...  [4.908s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [38.738s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.925s]
Building query seed array...  [2.021s]
Computing hash join...  [4.883s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [30.455s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.91s]
Building query seed array...  [2.123s]
Computing hash join...  [5.108s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [31.88s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.289s]
Building query seed array...  [1.734s]
Computing hash join...  [4.931s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [27.041s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.475s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [11.452s]
Sorting trace points...  [2.216s]
Computing alignments...  [57.058s]
Deallocating buffers...  [0.034s]
Loading trace points...  [0.103s]
Sorting trace points...  [1.698s]
Computing alignments...  [57.704s]
Deallocating buffers...  [0.044s]
Loading trace points...  [0.042s]
Sorting trace points...  [1.119s]
Computing alignments...  [30.156s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.194s]
Sorting trace points...  [1.136s]
Computing alignments...  [30.117s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.062s]
Sorting trace points...  [2.198s]
Computing alignments...  [57.545s]
Deallocating buffers...  [0.04s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.079s]
Computing alignments...  [29.202s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.042s]
Sorting trace points...  [1.13s]
Computing alignments...  [30.387s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.106s]
Computing alignments...  [30.792s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.12s]
Computing alignments...  [30.283s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.098s]
Computing alignments...  [31.156s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.034s]
Sorting trace points...  [1.018s]
Computing alignments...  [31.262s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.156s]
Computing alignments...  [31.057s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [0.895s]
Computing alignments...  [30.863s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [507.241s]
Deallocating reference...  [0.07s]
Loading reference sequences...  [30.214s]
Masking reference...  [30.886s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.959s]
Allocating buffers...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.255s]
Building query seed array...  [1.91s]
Computing hash join...  [5.111s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [71.661s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.832s]
Building query seed array...  [2.237s]
Computing hash join...  [5.156s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [45.931s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.756s]
Building query seed array...  [2.327s]
Computing hash join...  [5.15s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [40.99s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.172s]
Building query seed array...  [1.956s]
Computing hash join...  [5.112s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [36.713s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.111s]
Building query seed array...  [1.78s]
Computing hash join...  [4.975s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [39.736s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.473s]
Building query seed array...  [2.022s]
Computing hash join...  [4.936s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [30.601s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.179s]
Building query seed array...  [2.148s]
Computing hash join...  [4.856s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [33.549s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.941s]
Building query seed array...  [1.744s]
Computing hash join...  [4.886s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [28.094s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.133s]
Clearing query masking...  [1.495s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [11.643s]
Sorting trace points...  [2.188s]
Computing alignments...  [57.138s]
Deallocating buffers...  [0.036s]
Loading trace points...  [0.074s]
Sorting trace points...  [2.086s]
Computing alignments...  [57.381s]
Deallocating buffers...  [0.035s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.052s]
Computing alignments...  [29.515s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.126s]
Sorting trace points...  [1.126s]
Computing alignments...  [29.824s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.062s]
Sorting trace points...  [2.227s]
Computing alignments...  [57.036s]
Deallocating buffers...  [0.035s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.011s]
Computing alignments...  [29.117s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.062s]
Sorting trace points...  [0.905s]
Computing alignments...  [30.305s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.003s]
Sorting trace points...  [1.108s]
Computing alignments...  [30.527s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.088s]
Sorting trace points...  [1.114s]
Computing alignments...  [30.341s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.046s]
Computing alignments...  [30.74s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.114s]
Computing alignments...  [30.837s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.18s]
Computing alignments...  [30.885s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.168s]
Computing alignments...  [30.666s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
 [504.394s]
Deallocating reference...  [0.071s]
Loading reference sequences...  [29.639s]
Masking reference...  [30.833s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.731s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.493s]
Building query seed array...  [1.935s]
Computing hash join...  [5.13s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [73.021s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.362s]
Building query seed array...  [2.262s]
Computing hash join...  [5.115s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [46.208s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.43s]
Building query seed array...  [2.353s]
Computing hash join...  [5.046s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [42.007s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.409s]
Building query seed array...  [1.915s]
Computing hash join...  [5.079s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [37.209s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.271s]
Building query seed array...  [1.754s]
Computing hash join...  [4.839s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [40.134s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.336s]
Building query seed array...  [2.039s]
Computing hash join...  [4.837s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [30.988s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.164s]
Building query seed array...  [2.111s]
Computing hash join...  [4.858s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [32.625s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.627s]
Building query seed array...  [1.693s]
Computing hash join...  [4.893s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [28.26s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.133s]
Clearing query masking...  [1.53s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [11.303s]
Sorting trace points...  [2.259s]
Computing alignments...  [56.933s]
Deallocating buffers...  [0.034s]
Loading trace points...  [0.083s]
Sorting trace points...  [2.217s]
Computing alignments...  [57.902s]
Deallocating buffers...  [0.036s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.148s]
Computing alignments...  [29.821s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.126s]
Computing alignments...  [30.019s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.781s]
Computing alignments...  [57.252s]
Deallocating buffers...  [0.039s]
Loading trace points...  [0.002s]
Sorting trace points...  [1.109s]
Computing alignments...  [29.075s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.121s]
Computing alignments...  [30.276s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.111s]
Computing alignments...  [30.467s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.111s]
Computing alignments...  [30.277s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.122s]
Computing alignments...  [30.666s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.101s]
Sorting trace points...  [1.17s]
Computing alignments...  [30.973s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.209s]
Computing alignments...  [31.009s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.148s]
Computing alignments...  [30.501s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
 [505.157s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [23.786s]
Masking reference...  [26.024s]
Initializing dictionary...  [0.062s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [26.275s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.552s]
Building query seed array...  [1.916s]
Computing hash join...  [4.276s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [57.966s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [9.973s]
Building query seed array...  [2.244s]
Computing hash join...  [4.262s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [36.121s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [11.458s]
Building query seed array...  [2.308s]
Computing hash join...  [4.196s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [32.743s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [8.359s]
Building query seed array...  [1.923s]
Computing hash join...  [4.359s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [30.302s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [7.946s]
Building query seed array...  [1.762s]
Computing hash join...  [4.042s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [32.424s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [10.014s]
Building query seed array...  [2.005s]
Computing hash join...  [4.103s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [24.938s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [11.392s]
Building query seed array...  [2.186s]
Computing hash join...  [4.051s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [25.976s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [8.367s]
Building query seed array...  [1.677s]
Computing hash join...  [4.063s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [23.316s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.104s]
Clearing query masking...  [1.46s]
Opening temporary output file...  [0.026s]
Computing alignments... Loading trace points...  [9.569s]
Sorting trace points...  [1.836s]
Computing alignments...  [45.276s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.135s]
Sorting trace points...  [1.775s]
Computing alignments...  [45.852s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0.105s]
Sorting trace points...  [1.8s]
Computing alignments...  [46.926s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.139s]
Sorting trace points...  [1.765s]
Computing alignments...  [45.955s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0.151s]
Sorting trace points...  [1.803s]
Computing alignments...  [47.37s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.115s]
Sorting trace points...  [1.885s]
Computing alignments...  [48.504s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.142s]
Sorting trace points...  [1.883s]
Computing alignments...  [48.856s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0s]
Sorting trace points...  [1.868s]
Computing alignments...  [48.723s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [402.802s]
Deallocating reference...  [0.05s]
Loading reference sequences...  [0.085s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [1861.38s]
 [1861.38s]
Deallocating queries...  [0.058s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [3.676s]
 [5.93s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 16835s
Reported 2398523476 pairwise alignments, 2398523476 HSPs.
12449191 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C24_R2.fastp-trim.20230215.fq.gz complete: C24_R2.blastx.meganized.daa

Now MEGANizing C24_R2.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: C24_R2.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 100% (258.7s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.2s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (4,544.8s)
Total reads:       12,449,191
With hits:          12,449,191 
Alignments:      2,389,731,682
Assig. Taxonomy:    11,783,203
Assig. SEED:           103,041
Assig. EGGNOG:          47,398
Assig. GTDB:           385,464
Assig. EC:           2,003,209
Assig. INTERPRO2GO:  1,110,932
MinSupport set to: 6224
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.4s)
Min-supp. changes:       4,237
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (8.8s)
Min-supp. changes:       3,102
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (29.1s)
Binning reads Syncing
100% (0.4s)
Class. Taxonomy:           111
Class. SEED:               541
Class. EGGNOG:           1,902
Class. GTDB:                24
Class. EC:               2,441
Class. INTERPRO2GO:      7,976
Total time:  4,852s
Peak memory: 31 of 195.3G
MEGANization of C24_R2.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C25_R1.fastp-trim.20230215.fq.gz...
1d7fc56a7dfe763bcdfea837503f796b  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C25_R1.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C25_R1.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.285s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.754s]
Opening the output file...  [0s]
Loading query sequences...  [90.263s]
Masking queries...  [22.642s]
Algorithm: Double-indexed
Building query histograms...  [25.513s]
Loading reference sequences...  [30.628s]
Masking reference...  [32.095s]
Initializing dictionary...  [0.081s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.262s]
Allocating buffers...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.121s]
Building query seed array...  [2.434s]
Computing hash join...  [5.317s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [89.251s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.224s]
Building query seed array...  [2.973s]
Computing hash join...  [5.307s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [56.91s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.571s]
Building query seed array...  [3.626s]
Computing hash join...  [5.391s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [50.715s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.895s]
Building query seed array...  [2.471s]
Computing hash join...  [5.405s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [45.142s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.874s]
Building query seed array...  [2.252s]
Computing hash join...  [5.12s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [46.306s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.118s]
Building query seed array...  [2.526s]
Computing hash join...  [4.966s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [36.444s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.341s]
Building query seed array...  [2.702s]
Computing hash join...  [5.181s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [38.852s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.782s]
Building query seed array...  [2.272s]
Computing hash join...  [5.056s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [33.853s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.132s]
Clearing query masking...  [1.813s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.941s]
Sorting trace points...  [1.437s]
Computing alignments...  [35.825s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.302s]
Computing alignments...  [35.744s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.079s]
Computing alignments...  [36.114s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.335s]
Computing alignments...  [35.612s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.362s]
Computing alignments...  [35.336s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.173s]
Computing alignments...  [35.748s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.209s]
Sorting trace points...  [1.358s]
Computing alignments...  [35.813s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.298s]
Computing alignments...  [35.413s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.38s]
Computing alignments...  [36.507s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.107s]
Sorting trace points...  [1.438s]
Computing alignments...  [37.587s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.406s]
Computing alignments...  [37.386s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.09s]
Sorting trace points...  [1.287s]
Computing alignments...  [37.349s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.453s]
Computing alignments...  [37.166s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.187s]
Computing alignments...  [37.458s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.434s]
Computing alignments...  [37.5s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.395s]
Computing alignments...  [37.114s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [613.415s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [29.618s]
Masking reference...  [32.136s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.011s]
Building reference histograms...  [32.207s]
Allocating buffers...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.394s]
Building query seed array...  [2.501s]
Computing hash join...  [5.248s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [86.919s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.497s]
Building query seed array...  [2.938s]
Computing hash join...  [5.305s]
Masking low complexity seeds...  [0.249s]
Searching alignments...  [54.566s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.294s]
Building query seed array...  [2.993s]
Computing hash join...  [5.336s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [50.657s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.802s]
Building query seed array...  [2.469s]
Computing hash join...  [5.23s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [44.789s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.871s]
Building query seed array...  [2.351s]
Computing hash join...  [5.067s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [44.697s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.606s]
Building query seed array...  [2.594s]
Computing hash join...  [5.009s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [35.304s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.43s]
Building query seed array...  [2.701s]
Computing hash join...  [5.043s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [38.497s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.341s]
Building query seed array...  [2.248s]
Computing hash join...  [5.046s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [33.787s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.14s]
Clearing query masking...  [1.897s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.597s]
Sorting trace points...  [1.267s]
Computing alignments...  [35.507s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.068s]
Computing alignments...  [35.485s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.046s]
Computing alignments...  [35.831s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.317s]
Computing alignments...  [35.46s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.292s]
Computing alignments...  [35.092s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.32s]
Computing alignments...  [35.426s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.326s]
Computing alignments...  [35.574s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.023s]
Computing alignments...  [35.295s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.093s]
Sorting trace points...  [1.342s]
Computing alignments...  [36.291s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.441s]
Computing alignments...  [37.455s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.416s]
Computing alignments...  [37.418s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.119s]
Computing alignments...  [37.316s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.398s]
Computing alignments...  [37.1s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.424s]
Computing alignments...  [37.242s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.741s]
Sorting trace points...  [1.295s]
Computing alignments...  [37.275s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.403s]
Computing alignments...  [36.829s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [610.454s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.548s]
Masking reference...  [30.919s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.406s]
Allocating buffers...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.298s]
Building query seed array...  [2.526s]
Computing hash join...  [5.361s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [88.005s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.724s]
Building query seed array...  [2.889s]
Computing hash join...  [5.345s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [58.232s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.473s]
Building query seed array...  [3.067s]
Computing hash join...  [5.302s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [49.386s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.611s]
Building query seed array...  [2.443s]
Computing hash join...  [5.32s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [44.672s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.88s]
Building query seed array...  [2.258s]
Computing hash join...  [5.131s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [44.62s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.959s]
Building query seed array...  [2.517s]
Computing hash join...  [5.115s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [36.253s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.266s]
Building query seed array...  [2.726s]
Computing hash join...  [5.074s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [39.796s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.044s]
Building query seed array...  [2.29s]
Computing hash join...  [5.039s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [33.628s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.889s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.957s]
Sorting trace points...  [1.379s]
Computing alignments...  [35.679s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.362s]
Computing alignments...  [35.558s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.396s]
Computing alignments...  [35.904s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.088s]
Sorting trace points...  [1.355s]
Computing alignments...  [35.465s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.296s]
Computing alignments...  [35.197s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.277s]
Computing alignments...  [35.576s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.361s]
Computing alignments...  [35.64s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.126s]
Computing alignments...  [35.159s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.02s]
Computing alignments...  [36.248s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.408s]
Computing alignments...  [37.389s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.439s]
Computing alignments...  [37.305s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.656s]
Sorting trace points...  [1.439s]
Computing alignments...  [37.287s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.356s]
Computing alignments...  [37.04s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.44s]
Computing alignments...  [37.285s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.225s]
Computing alignments...  [37.319s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.39s]
Computing alignments...  [36.785s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [610.816s]
Deallocating reference...  [0.064s]
Loading reference sequences...  [33.945s]
Masking reference...  [31.228s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.318s]
Allocating buffers...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.172s]
Building query seed array...  [2.507s]
Computing hash join...  [5.309s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [86.662s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.454s]
Building query seed array...  [2.884s]
Computing hash join...  [5.269s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [56.645s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.507s]
Building query seed array...  [3.071s]
Computing hash join...  [5.314s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [47.826s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.04s]
Building query seed array...  [2.424s]
Computing hash join...  [5.252s]
Masking low complexity seeds...  [0.249s]
Searching alignments...  [44.245s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.88s]
Building query seed array...  [2.34s]
Computing hash join...  [5.033s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [44.282s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.949s]
Building query seed array...  [2.662s]
Computing hash join...  [5.134s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [36.069s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.997s]
Building query seed array...  [2.843s]
Computing hash join...  [4.982s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [38.4s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.843s]
Building query seed array...  [2.286s]
Computing hash join...  [5.002s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [33.206s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.127s]
Clearing query masking...  [1.877s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.851s]
Sorting trace points...  [1.449s]
Computing alignments...  [35.629s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.073s]
Sorting trace points...  [0.996s]
Computing alignments...  [35.765s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.085s]
Sorting trace points...  [1.362s]
Computing alignments...  [36.19s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.367s]
Computing alignments...  [35.55s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.151s]
Computing alignments...  [35.331s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.334s]
Computing alignments...  [35.648s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.042s]
Sorting trace points...  [1.359s]
Computing alignments...  [35.749s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.374s]
Computing alignments...  [35.3s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.392s]
Sorting trace points...  [1.096s]
Computing alignments...  [36.298s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.035s]
Sorting trace points...  [1.12s]
Computing alignments...  [37.575s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.003s]
Sorting trace points...  [1.047s]
Computing alignments...  [37.34s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.385s]
Computing alignments...  [37.338s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.239s]
Computing alignments...  [37.021s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.494s]
Computing alignments...  [37.338s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.092s]
Sorting trace points...  [1.428s]
Computing alignments...  [37.242s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.374s]
Computing alignments...  [36.87s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [611.072s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [29.596s]
Masking reference...  [30.846s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.626s]
Allocating buffers...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.291s]
Building query seed array...  [2.493s]
Computing hash join...  [5.293s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [85.779s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.693s]
Building query seed array...  [2.868s]
Computing hash join...  [5.265s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [56.887s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.422s]
Building query seed array...  [3.048s]
Computing hash join...  [5.411s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [49.111s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.079s]
Building query seed array...  [2.499s]
Computing hash join...  [5.241s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [43.494s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.86s]
Building query seed array...  [2.299s]
Computing hash join...  [5.015s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [44.328s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.992s]
Building query seed array...  [2.662s]
Computing hash join...  [5.062s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [35.489s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.147s]
Building query seed array...  [2.771s]
Computing hash join...  [5.059s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [38.873s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.001s]
Building query seed array...  [2.255s]
Computing hash join...  [5.023s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [33.287s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.14s]
Clearing query masking...  [1.987s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.932s]
Sorting trace points...  [1.418s]
Computing alignments...  [35.729s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.309s]
Computing alignments...  [35.558s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.384s]
Computing alignments...  [35.743s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.389s]
Computing alignments...  [35.259s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.28s]
Computing alignments...  [35.027s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.396s]
Computing alignments...  [35.404s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.388s]
Computing alignments...  [35.438s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.087s]
Computing alignments...  [35.043s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.295s]
Computing alignments...  [36.118s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.404s]
Computing alignments...  [37.268s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.094s]
Sorting trace points...  [1.095s]
Computing alignments...  [37.171s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.152s]
Computing alignments...  [37.135s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.036s]
Sorting trace points...  [1.405s]
Computing alignments...  [37.004s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.679s]
Sorting trace points...  [1.21s]
Computing alignments...  [37.174s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.474s]
Computing alignments...  [37.141s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.269s]
Computing alignments...  [36.759s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [608.638s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [32.381s]
Masking reference...  [31.336s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.648s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.407s]
Building query seed array...  [2.526s]
Computing hash join...  [5.253s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [84.594s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.155s]
Building query seed array...  [2.936s]
Computing hash join...  [5.285s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [54.526s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.295s]
Building query seed array...  [3.052s]
Computing hash join...  [5.21s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [50.287s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.978s]
Building query seed array...  [2.507s]
Computing hash join...  [5.333s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [42.388s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.864s]
Building query seed array...  [2.372s]
Computing hash join...  [4.988s]
Masking low complexity seeds...  [0.532s]
Searching alignments...  [42.862s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.216s]
Building query seed array...  [2.681s]
Computing hash join...  [5.048s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [35.187s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.439s]
Building query seed array...  [2.769s]
Computing hash join...  [5.091s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [37.255s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.69s]
Building query seed array...  [2.229s]
Computing hash join...  [5.018s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [34.007s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.139s]
Clearing query masking...  [1.887s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.831s]
Sorting trace points...  [1.43s]
Computing alignments...  [35.189s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.357s]
Computing alignments...  [35.325s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.332s]
Computing alignments...  [35.752s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.091s]
Sorting trace points...  [1.37s]
Computing alignments...  [35.288s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.04s]
Sorting trace points...  [1.31s]
Computing alignments...  [35.04s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.344s]
Computing alignments...  [35.347s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.379s]
Computing alignments...  [35.534s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.328s]
Computing alignments...  [35.004s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.385s]
Computing alignments...  [35.981s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.361s]
Computing alignments...  [37.21s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.067s]
Computing alignments...  [37.071s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.392s]
Computing alignments...  [37.061s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.418s]
Computing alignments...  [36.817s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.39s]
Computing alignments...  [37.086s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.107s]
Computing alignments...  [37.053s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
Sorting trace points...  [1.29s]
Computing alignments...  [36.647s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [606.797s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [29.608s]
Masking reference...  [31.004s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.715s]
Allocating buffers...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.124s]
Building query seed array...  [2.466s]
Computing hash join...  [5.275s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [89.256s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.676s]
Building query seed array...  [2.897s]
Computing hash join...  [5.294s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [56.917s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [14.011s]
Building query seed array...  [3.078s]
Computing hash join...  [5.302s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [50.419s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.872s]
Building query seed array...  [2.486s]
Computing hash join...  [5.21s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [45.489s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.365s]
Building query seed array...  [2.319s]
Computing hash join...  [5.106s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [46.222s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.67s]
Building query seed array...  [2.63s]
Computing hash join...  [5.055s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [35.72s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.494s]
Building query seed array...  [2.792s]
Computing hash join...  [4.981s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [38.67s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.201s]
Building query seed array...  [2.182s]
Computing hash join...  [5.04s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [34.047s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.131s]
Clearing query masking...  [1.92s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.917s]
Sorting trace points...  [1.459s]
Computing alignments...  [35.567s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.378s]
Computing alignments...  [35.53s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.362s]
Computing alignments...  [35.964s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.351s]
Computing alignments...  [35.341s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.574s]
Sorting trace points...  [1.334s]
Computing alignments...  [35.058s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.301s]
Computing alignments...  [35.401s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.332s]
Computing alignments...  [35.515s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.362s]
Computing alignments...  [35.137s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.037s]
Sorting trace points...  [1.392s]
Computing alignments...  [36.192s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.295s]
Computing alignments...  [37.389s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.424s]
Computing alignments...  [37.249s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.096s]
Computing alignments...  [37.259s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.031s]
Sorting trace points...  [1.054s]
Computing alignments...  [36.948s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.439s]
Computing alignments...  [37.204s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.43s]
Computing alignments...  [37.224s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.277s]
Computing alignments...  [36.773s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [609.538s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [31.691s]
Masking reference...  [30.817s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.78s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.758s]
Building query seed array...  [2.494s]
Computing hash join...  [5.375s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [87.05s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.563s]
Building query seed array...  [2.968s]
Computing hash join...  [5.239s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [56.031s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.342s]
Building query seed array...  [3.088s]
Computing hash join...  [5.324s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [48.685s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.789s]
Building query seed array...  [2.371s]
Computing hash join...  [5.227s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [44.94s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.901s]
Building query seed array...  [2.256s]
Computing hash join...  [5.099s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [44.451s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.323s]
Building query seed array...  [2.607s]
Computing hash join...  [5.083s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [35.233s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.139s]
Building query seed array...  [2.66s]
Computing hash join...  [5.07s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [38.564s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.946s]
Building query seed array...  [2.296s]
Computing hash join...  [4.995s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [33.998s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.13s]
Clearing query masking...  [1.815s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.972s]
Sorting trace points...  [1.461s]
Computing alignments...  [35.465s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.208s]
Sorting trace points...  [1.391s]
Computing alignments...  [35.49s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.103s]
Sorting trace points...  [1.345s]
Computing alignments...  [35.903s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.102s]
Sorting trace points...  [1.045s]
Computing alignments...  [35.586s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.151s]
Computing alignments...  [35.243s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.09s]
Sorting trace points...  [1.316s]
Computing alignments...  [35.524s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.203s]
Computing alignments...  [35.619s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.328s]
Computing alignments...  [35.265s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.396s]
Computing alignments...  [36.298s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.031s]
Sorting trace points...  [1.344s]
Computing alignments...  [37.4s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.443s]
Computing alignments...  [37.269s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.089s]
Sorting trace points...  [1.427s]
Computing alignments...  [37.295s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.093s]
Computing alignments...  [37.097s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.492s]
Computing alignments...  [37.287s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [1.379s]
Computing alignments...  [37.276s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.422s]
Computing alignments...  [36.784s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [610.432s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [29.712s]
Masking reference...  [30.844s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.207s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.128s]
Building query seed array...  [2.465s]
Computing hash join...  [5.279s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [87.449s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.716s]
Building query seed array...  [2.864s]
Computing hash join...  [5.322s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [55.172s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.426s]
Building query seed array...  [3.023s]
Computing hash join...  [5.28s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [48.04s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.67s]
Building query seed array...  [2.419s]
Computing hash join...  [5.294s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [44.776s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.893s]
Building query seed array...  [2.314s]
Computing hash join...  [5.105s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [44.699s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.137s]
Building query seed array...  [2.652s]
Computing hash join...  [5.08s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [35.417s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.277s]
Building query seed array...  [2.721s]
Computing hash join...  [5.054s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [38.401s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.14s]
Building query seed array...  [2.29s]
Computing hash join...  [5.009s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [34.323s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.127s]
Clearing query masking...  [1.879s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.2s]
Sorting trace points...  [1.331s]
Computing alignments...  [35.533s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.295s]
Computing alignments...  [35.472s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.38s]
Computing alignments...  [35.81s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.186s]
Computing alignments...  [35.347s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.062s]
Computing alignments...  [35.127s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.391s]
Computing alignments...  [35.33s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.334s]
Computing alignments...  [35.686s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.338s]
Computing alignments...  [35.233s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.097s]
Computing alignments...  [36.235s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.407s]
Computing alignments...  [37.485s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.429s]
Computing alignments...  [37.266s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.411s]
Computing alignments...  [37.584s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.034s]
Sorting trace points...  [1.302s]
Computing alignments...  [37.36s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.415s]
Computing alignments...  [37.332s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.097s]
Sorting trace points...  [1.416s]
Computing alignments...  [37.19s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.337s]
Computing alignments...  [36.783s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [610.18s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [29.796s]
Masking reference...  [31.271s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.341s]
Allocating buffers...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.488s]
Building query seed array...  [2.519s]
Computing hash join...  [5.332s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [88.482s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.428s]
Building query seed array...  [2.837s]
Computing hash join...  [5.275s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [56.034s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [14.132s]
Building query seed array...  [3.015s]
Computing hash join...  [5.267s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [49.044s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.956s]
Building query seed array...  [2.407s]
Computing hash join...  [5.244s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [44.424s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.029s]
Building query seed array...  [2.298s]
Computing hash join...  [5.053s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [44.149s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.139s]
Building query seed array...  [2.643s]
Computing hash join...  [5.171s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [36.25s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.202s]
Building query seed array...  [2.781s]
Computing hash join...  [5.111s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [38.823s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.042s]
Building query seed array...  [2.235s]
Computing hash join...  [5.011s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [33.832s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.138s]
Clearing query masking...  [1.844s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.877s]
Sorting trace points...  [1.439s]
Computing alignments...  [35.452s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.349s]
Computing alignments...  [35.384s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.364s]
Computing alignments...  [35.933s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.101s]
Sorting trace points...  [1.343s]
Computing alignments...  [35.414s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.138s]
Computing alignments...  [35.138s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.326s]
Computing alignments...  [35.337s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.038s]
Sorting trace points...  [1.357s]
Computing alignments...  [35.542s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.361s]
Computing alignments...  [35.157s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.097s]
Sorting trace points...  [1.046s]
Computing alignments...  [36.267s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.449s]
Computing alignments...  [37.418s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.456s]
Computing alignments...  [37.243s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.46s]
Computing alignments...  [37.254s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.329s]
Computing alignments...  [37.065s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.409s]
Computing alignments...  [37.247s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.457s]
Computing alignments...  [37.202s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.153s]
Computing alignments...  [36.894s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
 [609.654s]
Deallocating reference...  [0.063s]
Loading reference sequences...  [29.703s]
Masking reference...  [30.826s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.298s]
Allocating buffers...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.216s]
Building query seed array...  [2.516s]
Computing hash join...  [5.239s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [86.796s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.235s]
Building query seed array...  [2.9s]
Computing hash join...  [5.342s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [55.584s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.125s]
Building query seed array...  [3.035s]
Computing hash join...  [5.263s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [47.792s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.018s]
Building query seed array...  [2.404s]
Computing hash join...  [5.328s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [42.779s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.886s]
Building query seed array...  [2.192s]
Computing hash join...  [5.068s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [43.739s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.131s]
Building query seed array...  [2.605s]
Computing hash join...  [5.042s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [34.889s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.199s]
Building query seed array...  [2.722s]
Computing hash join...  [5.001s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [37.611s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.129s]
Building query seed array...  [2.224s]
Computing hash join...  [4.936s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [33.164s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.129s]
Clearing query masking...  [1.888s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.913s]
Sorting trace points...  [1.423s]
Computing alignments...  [35.218s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.347s]
Computing alignments...  [35.196s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.219s]
Sorting trace points...  [1.363s]
Computing alignments...  [35.626s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.378s]
Computing alignments...  [35.205s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.234s]
Computing alignments...  [34.887s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.326s]
Computing alignments...  [35.285s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.306s]
Computing alignments...  [35.359s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.285s]
Computing alignments...  [35.044s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.364s]
Computing alignments...  [36.118s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.473s]
Computing alignments...  [37.217s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.105s]
Sorting trace points...  [1.448s]
Computing alignments...  [37.093s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.434s]
Computing alignments...  [37.013s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.149s]
Computing alignments...  [36.894s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.414s]
Computing alignments...  [37.183s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.429s]
Computing alignments...  [37.235s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.454s]
Computing alignments...  [36.712s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [607.485s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [29.558s]
Masking reference...  [32.092s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.146s]
Allocating buffers...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.118s]
Building query seed array...  [2.462s]
Computing hash join...  [5.243s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [87.2s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.184s]
Building query seed array...  [2.898s]
Computing hash join...  [5.206s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [56.483s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.041s]
Building query seed array...  [3.152s]
Computing hash join...  [5.178s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [49.123s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.279s]
Building query seed array...  [2.542s]
Computing hash join...  [5.305s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [44.942s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.925s]
Building query seed array...  [2.256s]
Computing hash join...  [5.046s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [44.892s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.516s]
Building query seed array...  [2.594s]
Computing hash join...  [5.032s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [35.258s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.483s]
Building query seed array...  [2.779s]
Computing hash join...  [4.967s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [38.493s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.408s]
Building query seed array...  [2.257s]
Computing hash join...  [5.072s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [34.349s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.834s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.882s]
Sorting trace points...  [1.437s]
Computing alignments...  [35.505s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.024s]
Computing alignments...  [35.52s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.232s]
Computing alignments...  [35.81s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.176s]
Computing alignments...  [35.357s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.324s]
Computing alignments...  [35.086s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.308s]
Computing alignments...  [35.415s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.035s]
Sorting trace points...  [1.348s]
Computing alignments...  [35.566s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.259s]
Computing alignments...  [35.225s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.367s]
Computing alignments...  [36.219s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.056s]
Computing alignments...  [37.364s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0s]
Sorting trace points...  [1.445s]
Computing alignments...  [37.244s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.4s]
Computing alignments...  [37.256s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.183s]
Computing alignments...  [37.164s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.413s]
Computing alignments...  [37.293s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.112s]
Computing alignments...  [37.215s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.367s]
Computing alignments...  [36.863s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [608.486s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.625s]
Masking reference...  [30.817s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.134s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.511s]
Building query seed array...  [2.514s]
Computing hash join...  [5.316s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [87.685s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.435s]
Building query seed array...  [2.854s]
Computing hash join...  [5.261s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [57.216s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.6s]
Building query seed array...  [3.072s]
Computing hash join...  [5.29s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [50.119s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.6s]
Building query seed array...  [2.557s]
Computing hash join...  [5.309s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [43.689s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.961s]
Building query seed array...  [2.228s]
Computing hash join...  [5.023s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [45.228s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.716s]
Building query seed array...  [2.599s]
Computing hash join...  [5.047s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [35.934s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.685s]
Building query seed array...  [2.797s]
Computing hash join...  [5.001s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [39.134s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.006s]
Building query seed array...  [2.236s]
Computing hash join...  [5.063s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [34.798s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.144s]
Clearing query masking...  [1.886s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.938s]
Sorting trace points...  [1.43s]
Computing alignments...  [35.342s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.317s]
Computing alignments...  [35.467s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.316s]
Computing alignments...  [35.782s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.397s]
Computing alignments...  [35.233s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.091s]
Sorting trace points...  [1.312s]
Computing alignments...  [35.108s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.346s]
Computing alignments...  [35.483s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.376s]
Computing alignments...  [35.497s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.344s]
Computing alignments...  [35.103s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.069s]
Computing alignments...  [36.14s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.405s]
Computing alignments...  [37.323s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.43s]
Computing alignments...  [37.13s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.363s]
Computing alignments...  [37.113s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.706s]
Sorting trace points...  [1.458s]
Computing alignments...  [36.975s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.414s]
Computing alignments...  [37.204s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.412s]
Computing alignments...  [37.186s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.353s]
Computing alignments...  [36.688s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [609.246s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [25.408s]
Masking reference...  [25.231s]
Initializing dictionary...  [0.062s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [26.217s]
Allocating buffers...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.68s]
Building query seed array...  [2.501s]
Computing hash join...  [4.388s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [70.564s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [10.19s]
Building query seed array...  [2.868s]
Computing hash join...  [4.429s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [46.754s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [10.737s]
Building query seed array...  [3.011s]
Computing hash join...  [4.388s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [41.912s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [8.018s]
Building query seed array...  [2.481s]
Computing hash join...  [4.364s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [36.509s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [8.328s]
Building query seed array...  [2.269s]
Computing hash join...  [4.249s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [35.796s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [9.997s]
Building query seed array...  [2.573s]
Computing hash join...  [4.257s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [29.119s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [10.555s]
Building query seed array...  [2.704s]
Computing hash join...  [4.188s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [31.351s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [8.16s]
Building query seed array...  [2.296s]
Computing hash join...  [4.258s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [27.167s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.118s]
Clearing query masking...  [1.939s]
Opening temporary output file...  [0.023s]
Computing alignments... Loading trace points...  [12.259s]
Sorting trace points...  [2.383s]
Computing alignments...  [55.989s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.114s]
Sorting trace points...  [1.132s]
Computing alignments...  [28.892s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.153s]
Sorting trace points...  [2.067s]
Computing alignments...  [56.104s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.125s]
Sorting trace points...  [2.177s]
Computing alignments...  [56.528s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.82s]
Computing alignments...  [56.722s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.142s]
Computing alignments...  [29.861s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.002s]
Sorting trace points...  [1.158s]
Computing alignments...  [29.775s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.153s]
Computing alignments...  [29.748s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.183s]
Computing alignments...  [29.612s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.178s]
Computing alignments...  [29.686s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.104s]
Computing alignments...  [29.681s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.069s]
Computing alignments...  [29.34s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [492.731s]
Deallocating reference...  [0.049s]
Loading reference sequences...  [0.099s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [2209.5s]
 [2209.5s]
Deallocating queries...  [0.065s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [3.893s]
 [5.23s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 19652.7s
Reported 2840292577 pairwise alignments, 2840292577 HSPs.
16137525 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C25_R1.fastp-trim.20230215.fq.gz complete: C25_R1.blastx.meganized.daa

Now MEGANizing C25_R1.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: C25_R1.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 100% (279.1s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.2s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (5,342.2s)
Total reads:       16,137,525
With hits:          16,137,525 
Alignments:      2,835,964,264
Assig. Taxonomy:    15,024,011
Assig. SEED:           122,429
Assig. EGGNOG:          61,608
Assig. GTDB:           468,393
Assig. EC:           2,574,941
Assig. INTERPRO2GO:  1,350,893
MinSupport set to: 8068
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.5s)
Min-supp. changes:       4,327
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (14.8s)
Min-supp. changes:       3,361
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (71.7s)
Binning reads Syncing
100% (0.4s)
Class. Taxonomy:            61
Class. SEED:               510
Class. EGGNOG:           1,813
Class. GTDB:                19
Class. EC:               2,422
Class. INTERPRO2GO:      8,111
Total time:  5,719s
Peak memory: 32.9 of 195.3G
MEGANization of C25_R1.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C25_R2.fastp-trim.20230215.fq.gz...
3b714c828f34210412b6382321e85c65  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C25_R2.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C25_R2.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.298s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.723s]
Opening the output file...  [0s]
Loading query sequences...  [90.163s]
Masking queries...  [22.912s]
Algorithm: Double-indexed
Building query histograms...  [20.957s]
Loading reference sequences...  [31.555s]
Masking reference...  [32.026s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.829s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.683s]
Building query seed array...  [2.449s]
Computing hash join...  [5.634s]
Masking low complexity seeds...  [0.285s]
Searching alignments...  [87.177s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.543s]
Building query seed array...  [2.872s]
Computing hash join...  [5.435s]
Masking low complexity seeds...  [0.288s]
Searching alignments...  [55.062s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.993s]
Building query seed array...  [3.048s]
Computing hash join...  [5.373s]
Masking low complexity seeds...  [0.286s]
Searching alignments...  [49.585s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.111s]
Building query seed array...  [2.574s]
Computing hash join...  [5.428s]
Masking low complexity seeds...  [0.288s]
Searching alignments...  [44.791s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.617s]
Building query seed array...  [2.324s]
Computing hash join...  [5.272s]
Masking low complexity seeds...  [0.278s]
Searching alignments...  [48.003s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.276s]
Building query seed array...  [2.646s]
Computing hash join...  [5.148s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [37.3s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.316s]
Building query seed array...  [2.648s]
Computing hash join...  [5.152s]
Masking low complexity seeds...  [0.268s]
Searching alignments...  [39.298s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.317s]
Building query seed array...  [2.299s]
Computing hash join...  [5.095s]
Masking low complexity seeds...  [0.269s]
Searching alignments...  [35.357s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.144s]
Clearing query masking...  [1.918s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.108s]
Sorting trace points...  [1.404s]
Computing alignments...  [35.191s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.23s]
Computing alignments...  [35.005s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.306s]
Computing alignments...  [35.138s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.069s]
Computing alignments...  [34.81s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.06s]
Sorting trace points...  [0.978s]
Computing alignments...  [35.102s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.118s]
Computing alignments...  [35.285s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.3s]
Computing alignments...  [34.735s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.038s]
Sorting trace points...  [1.251s]
Computing alignments...  [34.701s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.039s]
Sorting trace points...  [1.397s]
Computing alignments...  [36.121s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.43s]
Computing alignments...  [38.064s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.444s]
Computing alignments...  [38.179s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.417s]
Computing alignments...  [37.888s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.097s]
Sorting trace points...  [1.489s]
Computing alignments...  [37.889s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.442s]
Computing alignments...  [37.879s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.377s]
Computing alignments...  [37.861s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.41s]
Computing alignments...  [37.448s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [610.543s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [30.927s]
Masking reference...  [30.927s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.153s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.025s]
Building query seed array...  [2.559s]
Computing hash join...  [5.434s]
Masking low complexity seeds...  [0.28s]
Searching alignments...  [85.435s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.28s]
Building query seed array...  [2.941s]
Computing hash join...  [5.461s]
Masking low complexity seeds...  [0.287s]
Searching alignments...  [53.507s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.509s]
Building query seed array...  [3.13s]
Computing hash join...  [5.414s]
Masking low complexity seeds...  [0.294s]
Searching alignments...  [48.847s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.086s]
Building query seed array...  [2.476s]
Computing hash join...  [5.336s]
Masking low complexity seeds...  [0.284s]
Searching alignments...  [42.886s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.016s]
Building query seed array...  [2.303s]
Computing hash join...  [5.183s]
Masking low complexity seeds...  [0.281s]
Searching alignments...  [46.686s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.537s]
Building query seed array...  [2.668s]
Computing hash join...  [5.25s]
Masking low complexity seeds...  [0.271s]
Searching alignments...  [36.418s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.497s]
Building query seed array...  [2.818s]
Computing hash join...  [5.114s]
Masking low complexity seeds...  [0.273s]
Searching alignments...  [39.124s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.281s]
Building query seed array...  [2.281s]
Computing hash join...  [5.127s]
Masking low complexity seeds...  [0.27s]
Searching alignments...  [33.521s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.132s]
Clearing query masking...  [1.961s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.793s]
Sorting trace points...  [1.381s]
Computing alignments...  [34.945s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.354s]
Computing alignments...  [34.818s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.366s]
Computing alignments...  [34.949s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.333s]
Computing alignments...  [34.688s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.352s]
Computing alignments...  [34.995s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.102s]
Sorting trace points...  [1.317s]
Computing alignments...  [35.123s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.042s]
Sorting trace points...  [0.992s]
Computing alignments...  [34.548s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.027s]
Computing alignments...  [34.548s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.093s]
Sorting trace points...  [1.539s]
Computing alignments...  [35.954s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.344s]
Computing alignments...  [38.007s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.465s]
Computing alignments...  [38.115s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.417s]
Computing alignments...  [37.88s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.459s]
Computing alignments...  [37.737s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.408s]
Computing alignments...  [37.682s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.526s]
Computing alignments...  [37.762s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.126s]
Computing alignments...  [37.458s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
 [609.134s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [31.644s]
Masking reference...  [31.946s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.224s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.056s]
Building query seed array...  [2.554s]
Computing hash join...  [5.451s]
Masking low complexity seeds...  [0.284s]
Searching alignments...  [88.329s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.55s]
Building query seed array...  [2.875s]
Computing hash join...  [5.322s]
Masking low complexity seeds...  [0.279s]
Searching alignments...  [56.067s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.532s]
Building query seed array...  [3.044s]
Computing hash join...  [5.398s]
Masking low complexity seeds...  [0.289s]
Searching alignments...  [49.119s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.079s]
Building query seed array...  [2.487s]
Computing hash join...  [5.433s]
Masking low complexity seeds...  [0.289s]
Searching alignments...  [43.389s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.034s]
Building query seed array...  [2.268s]
Computing hash join...  [5.169s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [47.236s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.055s]
Building query seed array...  [2.602s]
Computing hash join...  [5.25s]
Masking low complexity seeds...  [0.267s]
Searching alignments...  [36.79s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.489s]
Building query seed array...  [2.747s]
Computing hash join...  [5.217s]
Masking low complexity seeds...  [0.284s]
Searching alignments...  [40.341s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.17s]
Building query seed array...  [2.14s]
Computing hash join...  [5.167s]
Masking low complexity seeds...  [0.274s]
Searching alignments...  [34.246s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.143s]
Clearing query masking...  [1.888s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.071s]
Sorting trace points...  [1.385s]
Computing alignments...  [35.046s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.022s]
Computing alignments...  [34.866s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.314s]
Computing alignments...  [35.158s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.319s]
Computing alignments...  [34.81s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.259s]
Computing alignments...  [35.052s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.049s]
Sorting trace points...  [0.992s]
Computing alignments...  [35.221s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.295s]
Computing alignments...  [34.787s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.335s]
Computing alignments...  [34.67s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.778s]
Sorting trace points...  [1.416s]
Computing alignments...  [35.958s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.443s]
Computing alignments...  [37.976s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.409s]
Computing alignments...  [38.242s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.423s]
Computing alignments...  [37.92s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.092s]
Sorting trace points...  [1.457s]
Computing alignments...  [37.956s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.406s]
Computing alignments...  [37.766s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.389s]
Computing alignments...  [37.895s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.383s]
Computing alignments...  [37.569s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [611.558s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [29.526s]
Masking reference...  [30.849s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.529s]
Allocating buffers...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.329s]
Building query seed array...  [2.476s]
Computing hash join...  [5.537s]
Masking low complexity seeds...  [0.291s]
Searching alignments...  [86.71s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.684s]
Building query seed array...  [2.929s]
Computing hash join...  [5.474s]
Masking low complexity seeds...  [0.287s]
Searching alignments...  [53.544s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.11s]
Building query seed array...  [3.124s]
Computing hash join...  [5.47s]
Masking low complexity seeds...  [0.284s]
Searching alignments...  [49.467s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.038s]
Building query seed array...  [2.501s]
Computing hash join...  [5.415s]
Masking low complexity seeds...  [0.281s]
Searching alignments...  [43.267s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.898s]
Building query seed array...  [2.285s]
Computing hash join...  [5.111s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [45.9s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.408s]
Building query seed array...  [2.577s]
Computing hash join...  [5.105s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [36.805s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.5s]
Building query seed array...  [2.733s]
Computing hash join...  [5.147s]
Masking low complexity seeds...  [0.275s]
Searching alignments...  [39.077s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.995s]
Building query seed array...  [2.29s]
Computing hash join...  [5.182s]
Masking low complexity seeds...  [0.278s]
Searching alignments...  [34.043s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.13s]
Clearing query masking...  [1.971s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.209s]
Sorting trace points...  [1.381s]
Computing alignments...  [35.088s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.021s]
Computing alignments...  [34.968s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.02s]
Computing alignments...  [35.075s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.364s]
Computing alignments...  [34.892s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.088s]
Sorting trace points...  [1.153s]
Computing alignments...  [34.983s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.115s]
Computing alignments...  [35.269s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.118s]
Computing alignments...  [34.771s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.089s]
Computing alignments...  [34.731s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.297s]
Computing alignments...  [36.055s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.404s]
Computing alignments...  [38.019s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.479s]
Computing alignments...  [38.29s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.462s]
Computing alignments...  [37.973s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.099s]
Sorting trace points...  [1.129s]
Computing alignments...  [37.986s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.08s]
Computing alignments...  [37.948s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.454s]
Computing alignments...  [37.934s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.405s]
Computing alignments...  [37.538s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [609.977s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [29.939s]
Masking reference...  [32.169s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [31.695s]
Allocating buffers...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.355s]
Building query seed array...  [2.469s]
Computing hash join...  [5.522s]
Masking low complexity seeds...  [0.283s]
Searching alignments...  [87.41s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.881s]
Building query seed array...  [2.877s]
Computing hash join...  [5.543s]
Masking low complexity seeds...  [0.28s]
Searching alignments...  [53.771s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.642s]
Building query seed array...  [3.041s]
Computing hash join...  [5.439s]
Masking low complexity seeds...  [0.289s]
Searching alignments...  [49.209s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.327s]
Building query seed array...  [2.498s]
Computing hash join...  [5.45s]
Masking low complexity seeds...  [0.283s]
Searching alignments...  [43.509s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.925s]
Building query seed array...  [2.273s]
Computing hash join...  [5.221s]
Masking low complexity seeds...  [0.272s]
Searching alignments...  [46.146s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.061s]
Building query seed array...  [2.674s]
Computing hash join...  [5.197s]
Masking low complexity seeds...  [0.271s]
Searching alignments...  [36.616s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.017s]
Building query seed array...  [2.694s]
Computing hash join...  [5.18s]
Masking low complexity seeds...  [0.271s]
Searching alignments...  [38.793s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.199s]
Building query seed array...  [2.326s]
Computing hash join...  [5.115s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [33.679s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.834s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.757s]
Sorting trace points...  [1.433s]
Computing alignments...  [34.884s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.117s]
Sorting trace points...  [1.324s]
Computing alignments...  [34.807s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.329s]
Computing alignments...  [34.874s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.287s]
Computing alignments...  [34.636s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.337s]
Computing alignments...  [34.855s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.32s]
Computing alignments...  [35.13s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.107s]
Computing alignments...  [34.49s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.358s]
Computing alignments...  [34.47s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [0.987s]
Computing alignments...  [35.885s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.467s]
Computing alignments...  [37.943s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.161s]
Sorting trace points...  [1.463s]
Computing alignments...  [38.126s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.492s]
Computing alignments...  [37.867s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.466s]
Computing alignments...  [37.832s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.095s]
Computing alignments...  [37.759s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.441s]
Computing alignments...  [37.787s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.34s]
Computing alignments...  [37.414s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [608.149s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.492s]
Masking reference...  [32.116s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [31.92s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.437s]
Building query seed array...  [2.505s]
Computing hash join...  [5.451s]
Masking low complexity seeds...  [0.286s]
Searching alignments...  [85.539s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.108s]
Building query seed array...  [2.963s]
Computing hash join...  [5.402s]
Masking low complexity seeds...  [0.281s]
Searching alignments...  [53.39s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.589s]
Building query seed array...  [3.088s]
Computing hash join...  [5.439s]
Masking low complexity seeds...  [0.286s]
Searching alignments...  [49.203s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.36s]
Building query seed array...  [2.436s]
Computing hash join...  [5.328s]
Masking low complexity seeds...  [0.273s]
Searching alignments...  [44.043s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.855s]
Building query seed array...  [2.194s]
Computing hash join...  [5.135s]
Masking low complexity seeds...  [0.269s]
Searching alignments...  [45.754s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.352s]
Building query seed array...  [2.617s]
Computing hash join...  [5.157s]
Masking low complexity seeds...  [0.267s]
Searching alignments...  [36.297s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.328s]
Building query seed array...  [2.784s]
Computing hash join...  [5.196s]
Masking low complexity seeds...  [0.27s]
Searching alignments...  [37.798s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.986s]
Building query seed array...  [2.218s]
Computing hash join...  [5.148s]
Masking low complexity seeds...  [0.274s]
Searching alignments...  [33.986s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.924s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.779s]
Sorting trace points...  [1.426s]
Computing alignments...  [34.701s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.325s]
Computing alignments...  [34.672s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.254s]
Computing alignments...  [34.777s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.072s]
Sorting trace points...  [0.983s]
Computing alignments...  [34.474s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.091s]
Sorting trace points...  [1.341s]
Computing alignments...  [34.767s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.283s]
Computing alignments...  [34.99s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.093s]
Sorting trace points...  [1.297s]
Computing alignments...  [34.429s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.28s]
Computing alignments...  [34.327s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.362s]
Computing alignments...  [35.69s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.027s]
Sorting trace points...  [1.453s]
Computing alignments...  [37.623s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.311s]
Computing alignments...  [37.878s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.481s]
Computing alignments...  [37.54s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.403s]
Computing alignments...  [37.641s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.445s]
Computing alignments...  [37.599s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.457s]
Computing alignments...  [37.568s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.406s]
Computing alignments...  [37.124s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [605.374s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [29.458s]
Masking reference...  [30.84s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [33.017s]
Allocating buffers...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.617s]
Building query seed array...  [2.492s]
Computing hash join...  [5.478s]
Masking low complexity seeds...  [0.282s]
Searching alignments...  [85.586s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.669s]
Building query seed array...  [2.915s]
Computing hash join...  [5.44s]
Masking low complexity seeds...  [0.284s]
Searching alignments...  [55.682s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.46s]
Building query seed array...  [3.067s]
Computing hash join...  [5.411s]
Masking low complexity seeds...  [0.286s]
Searching alignments...  [50.711s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.242s]
Building query seed array...  [2.621s]
Computing hash join...  [5.34s]
Masking low complexity seeds...  [0.278s]
Searching alignments...  [44.253s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.051s]
Building query seed array...  [2.3s]
Computing hash join...  [5.167s]
Masking low complexity seeds...  [0.276s]
Searching alignments...  [47.946s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.642s]
Building query seed array...  [2.613s]
Computing hash join...  [5.231s]
Masking low complexity seeds...  [0.271s]
Searching alignments...  [36.622s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.302s]
Building query seed array...  [2.815s]
Computing hash join...  [5.141s]
Masking low complexity seeds...  [0.268s]
Searching alignments...  [40.331s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.069s]
Building query seed array...  [2.303s]
Computing hash join...  [5.136s]
Masking low complexity seeds...  [0.276s]
Searching alignments...  [35.206s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.129s]
Clearing query masking...  [1.917s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.914s]
Sorting trace points...  [1.41s]
Computing alignments...  [34.972s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.357s]
Computing alignments...  [35.038s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.33s]
Computing alignments...  [35.145s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.111s]
Computing alignments...  [34.725s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.163s]
Computing alignments...  [34.957s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.279s]
Computing alignments...  [35.18s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.3s]
Computing alignments...  [34.599s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.159s]
Computing alignments...  [34.537s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.385s]
Computing alignments...  [35.98s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.393s]
Computing alignments...  [37.982s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.42s]
Computing alignments...  [38.069s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.459s]
Computing alignments...  [37.745s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.087s]
Computing alignments...  [37.825s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.466s]
Computing alignments...  [37.753s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.463s]
Computing alignments...  [37.912s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.449s]
Computing alignments...  [37.456s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [609.323s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [30.487s]
Masking reference...  [31.43s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.198s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.398s]
Building query seed array...  [2.507s]
Computing hash join...  [5.448s]
Masking low complexity seeds...  [0.278s]
Searching alignments...  [86.572s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.344s]
Building query seed array...  [2.902s]
Computing hash join...  [5.471s]
Masking low complexity seeds...  [0.281s]
Searching alignments...  [56.085s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.388s]
Building query seed array...  [3.051s]
Computing hash join...  [5.368s]
Masking low complexity seeds...  [0.285s]
Searching alignments...  [49.396s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.109s]
Building query seed array...  [2.508s]
Computing hash join...  [5.376s]
Masking low complexity seeds...  [0.284s]
Searching alignments...  [44.081s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.12s]
Building query seed array...  [2.261s]
Computing hash join...  [5.155s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [46.347s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.508s]
Building query seed array...  [2.65s]
Computing hash join...  [5.202s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [37.63s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.266s]
Building query seed array...  [2.768s]
Computing hash join...  [5.24s]
Masking low complexity seeds...  [0.27s]
Searching alignments...  [39.184s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.913s]
Building query seed array...  [2.253s]
Computing hash join...  [5.176s]
Masking low complexity seeds...  [0.273s]
Searching alignments...  [33.638s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.822s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.85s]
Sorting trace points...  [1.321s]
Computing alignments...  [34.85s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.214s]
Computing alignments...  [34.93s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.352s]
Computing alignments...  [35.051s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.352s]
Computing alignments...  [34.783s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.612s]
Sorting trace points...  [1.175s]
Computing alignments...  [34.974s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.287s]
Computing alignments...  [35.13s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.317s]
Computing alignments...  [34.592s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.088s]
Computing alignments...  [34.577s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.042s]
Sorting trace points...  [1.102s]
Computing alignments...  [35.958s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.286s]
Sorting trace points...  [1.45s]
Computing alignments...  [38.051s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.489s]
Computing alignments...  [38.088s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.387s]
Computing alignments...  [37.904s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.141s]
Sorting trace points...  [1.151s]
Computing alignments...  [38s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.118s]
Computing alignments...  [37.96s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.064s]
Computing alignments...  [37.896s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.223s]
Computing alignments...  [37.445s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
 [609.038s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [29.683s]
Masking reference...  [30.851s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.681s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.551s]
Building query seed array...  [2.499s]
Computing hash join...  [5.42s]
Masking low complexity seeds...  [0.275s]
Searching alignments...  [86.69s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [11.962s]
Building query seed array...  [2.977s]
Computing hash join...  [5.416s]
Masking low complexity seeds...  [0.279s]
Searching alignments...  [54.93s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.26s]
Building query seed array...  [3.046s]
Computing hash join...  [5.39s]
Masking low complexity seeds...  [0.3s]
Searching alignments...  [49.614s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.342s]
Building query seed array...  [2.515s]
Computing hash join...  [5.412s]
Masking low complexity seeds...  [0.289s]
Searching alignments...  [44.589s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.11s]
Building query seed array...  [2.234s]
Computing hash join...  [5.137s]
Masking low complexity seeds...  [0.272s]
Searching alignments...  [48.097s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.551s]
Building query seed array...  [2.708s]
Computing hash join...  [5.136s]
Masking low complexity seeds...  [0.27s]
Searching alignments...  [37.345s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.08s]
Building query seed array...  [2.891s]
Computing hash join...  [5.213s]
Masking low complexity seeds...  [0.276s]
Searching alignments...  [39.475s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.59s]
Building query seed array...  [2.316s]
Computing hash join...  [5.28s]
Masking low complexity seeds...  [0.271s]
Searching alignments...  [34.738s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.892s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.845s]
Sorting trace points...  [1.371s]
Computing alignments...  [35.021s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.224s]
Computing alignments...  [35.06s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.28s]
Computing alignments...  [35.126s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.058s]
Sorting trace points...  [0.966s]
Computing alignments...  [34.837s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.332s]
Computing alignments...  [35.076s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.346s]
Computing alignments...  [35.169s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.279s]
Computing alignments...  [34.664s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.033s]
Sorting trace points...  [1.217s]
Computing alignments...  [34.592s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.416s]
Computing alignments...  [35.904s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.885s]
Sorting trace points...  [1.404s]
Computing alignments...  [37.937s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.471s]
Computing alignments...  [38.148s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.277s]
Computing alignments...  [37.936s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.383s]
Computing alignments...  [38.03s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.44s]
Computing alignments...  [37.995s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.462s]
Computing alignments...  [37.991s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.43s]
Computing alignments...  [37.451s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [611.182s]
Deallocating reference...  [0.063s]
Loading reference sequences...  [29.615s]
Masking reference...  [30.842s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.724s]
Allocating buffers...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.618s]
Building query seed array...  [2.531s]
Computing hash join...  [5.39s]
Masking low complexity seeds...  [0.278s]
Searching alignments...  [87.696s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.505s]
Building query seed array...  [2.989s]
Computing hash join...  [5.331s]
Masking low complexity seeds...  [0.285s]
Searching alignments...  [55.145s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.36s]
Building query seed array...  [3.075s]
Computing hash join...  [5.398s]
Masking low complexity seeds...  [0.29s]
Searching alignments...  [50.785s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.197s]
Building query seed array...  [2.507s]
Computing hash join...  [5.367s]
Masking low complexity seeds...  [0.277s]
Searching alignments...  [45.608s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.147s]
Building query seed array...  [2.244s]
Computing hash join...  [5.248s]
Masking low complexity seeds...  [0.266s]
Searching alignments...  [47.959s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [13.037s]
Building query seed array...  [2.694s]
Computing hash join...  [5.06s]
Masking low complexity seeds...  [0.276s]
Searching alignments...  [36.976s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.393s]
Building query seed array...  [2.721s]
Computing hash join...  [5.213s]
Masking low complexity seeds...  [0.286s]
Searching alignments...  [39.604s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.941s]
Building query seed array...  [2.248s]
Computing hash join...  [5.157s]
Masking low complexity seeds...  [0.268s]
Searching alignments...  [34.642s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.128s]
Clearing query masking...  [1.857s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.878s]
Sorting trace points...  [1.411s]
Computing alignments...  [34.722s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.344s]
Computing alignments...  [34.846s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.054s]
Computing alignments...  [34.998s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.311s]
Computing alignments...  [34.671s]
Deallocating buffers...  [0.015s]
Loading trace points...  [1.116s]
Sorting trace points...  [1.148s]
Computing alignments...  [34.982s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.348s]
Computing alignments...  [35.08s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.321s]
Computing alignments...  [34.518s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.004s]
Computing alignments...  [34.523s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.382s]
Computing alignments...  [35.893s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.244s]
Computing alignments...  [37.944s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.425s]
Computing alignments...  [38.18s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.466s]
Computing alignments...  [37.835s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.094s]
Sorting trace points...  [1.526s]
Computing alignments...  [37.805s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.495s]
Computing alignments...  [37.788s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.417s]
Computing alignments...  [37.873s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.447s]
Computing alignments...  [37.385s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [609.699s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [32.592s]
Masking reference...  [32.158s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [31.745s]
Allocating buffers...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.134s]
Building query seed array...  [2.519s]
Computing hash join...  [5.475s]
Masking low complexity seeds...  [0.291s]
Searching alignments...  [85.879s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.177s]
Building query seed array...  [2.916s]
Computing hash join...  [5.462s]
Masking low complexity seeds...  [0.279s]
Searching alignments...  [54.833s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.523s]
Building query seed array...  [3.102s]
Computing hash join...  [5.365s]
Masking low complexity seeds...  [0.284s]
Searching alignments...  [49.662s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.213s]
Building query seed array...  [2.461s]
Computing hash join...  [5.442s]
Masking low complexity seeds...  [0.281s]
Searching alignments...  [42.763s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.717s]
Building query seed array...  [2.264s]
Computing hash join...  [5.237s]
Masking low complexity seeds...  [0.273s]
Searching alignments...  [46.112s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.604s]
Building query seed array...  [2.654s]
Computing hash join...  [5.122s]
Masking low complexity seeds...  [0.271s]
Searching alignments...  [37.399s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.341s]
Building query seed array...  [2.699s]
Computing hash join...  [5.126s]
Masking low complexity seeds...  [0.271s]
Searching alignments...  [39.805s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.039s]
Building query seed array...  [2.268s]
Computing hash join...  [5.181s]
Masking low complexity seeds...  [0.277s]
Searching alignments...  [33.376s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.887s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.977s]
Sorting trace points...  [1.355s]
Computing alignments...  [34.632s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.28s]
Computing alignments...  [34.65s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.012s]
Computing alignments...  [34.769s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.099s]
Sorting trace points...  [1.009s]
Computing alignments...  [34.536s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.318s]
Computing alignments...  [34.886s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.034s]
Sorting trace points...  [1.327s]
Computing alignments...  [35.15s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.278s]
Computing alignments...  [34.546s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.3s]
Computing alignments...  [34.48s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.371s]
Computing alignments...  [35.803s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.212s]
Computing alignments...  [37.853s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.443s]
Computing alignments...  [38.004s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.451s]
Computing alignments...  [37.669s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.232s]
Computing alignments...  [37.704s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.135s]
Computing alignments...  [37.709s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.452s]
Computing alignments...  [37.75s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.43s]
Computing alignments...  [37.349s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [606.361s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.69s]
Masking reference...  [31.526s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.466s]
Allocating buffers...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.006s]
Building query seed array...  [2.528s]
Computing hash join...  [5.408s]
Masking low complexity seeds...  [0.288s]
Searching alignments...  [86.801s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.625s]
Building query seed array...  [2.843s]
Computing hash join...  [5.391s]
Masking low complexity seeds...  [0.29s]
Searching alignments...  [54.336s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.629s]
Building query seed array...  [3.129s]
Computing hash join...  [5.432s]
Masking low complexity seeds...  [0.288s]
Searching alignments...  [51.685s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.141s]
Building query seed array...  [2.567s]
Computing hash join...  [5.419s]
Masking low complexity seeds...  [0.286s]
Searching alignments...  [45.27s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.985s]
Building query seed array...  [2.26s]
Computing hash join...  [5.138s]
Masking low complexity seeds...  [0.272s]
Searching alignments...  [47.086s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.469s]
Building query seed array...  [2.553s]
Computing hash join...  [5.142s]
Masking low complexity seeds...  [0.271s]
Searching alignments...  [37.293s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.556s]
Building query seed array...  [2.785s]
Computing hash join...  [5.303s]
Masking low complexity seeds...  [0.273s]
Searching alignments...  [40.372s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.935s]
Building query seed array...  [2.246s]
Computing hash join...  [5.172s]
Masking low complexity seeds...  [0.271s]
Searching alignments...  [34.211s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.141s]
Clearing query masking...  [1.84s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.879s]
Sorting trace points...  [1.363s]
Computing alignments...  [35.089s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.294s]
Computing alignments...  [34.932s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.189s]
Computing alignments...  [34.965s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.34s]
Computing alignments...  [34.635s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.322s]
Computing alignments...  [34.904s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.187s]
Computing alignments...  [35.149s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.279s]
Computing alignments...  [34.562s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.172s]
Computing alignments...  [34.59s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.355s]
Computing alignments...  [35.983s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.066s]
Computing alignments...  [37.907s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.301s]
Computing alignments...  [38.081s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.294s]
Computing alignments...  [37.888s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.44s]
Computing alignments...  [37.791s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.455s]
Computing alignments...  [37.759s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.508s]
Computing alignments...  [37.802s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.347s]
Computing alignments...  [37.433s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [608.445s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [29.748s]
Masking reference...  [32.185s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [31.646s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.618s]
Building query seed array...  [2.482s]
Computing hash join...  [5.472s]
Masking low complexity seeds...  [0.287s]
Searching alignments...  [87.952s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.552s]
Building query seed array...  [2.862s]
Computing hash join...  [5.471s]
Masking low complexity seeds...  [0.283s]
Searching alignments...  [54.276s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.255s]
Building query seed array...  [3.186s]
Computing hash join...  [5.353s]
Masking low complexity seeds...  [0.283s]
Searching alignments...  [51.574s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.029s]
Building query seed array...  [2.555s]
Computing hash join...  [5.441s]
Masking low complexity seeds...  [0.283s]
Searching alignments...  [44.515s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.896s]
Building query seed array...  [2.31s]
Computing hash join...  [5.121s]
Masking low complexity seeds...  [0.268s]
Searching alignments...  [47.255s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.61s]
Building query seed array...  [2.615s]
Computing hash join...  [5.19s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [37.258s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.22s]
Building query seed array...  [2.843s]
Computing hash join...  [5.123s]
Masking low complexity seeds...  [0.267s]
Searching alignments...  [40.789s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.521s]
Building query seed array...  [2.205s]
Computing hash join...  [5.133s]
Masking low complexity seeds...  [0.265s]
Searching alignments...  [34.334s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.895s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.972s]
Sorting trace points...  [1.397s]
Computing alignments...  [34.86s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.149s]
Sorting trace points...  [1.307s]
Computing alignments...  [34.812s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.054s]
Computing alignments...  [34.928s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.309s]
Computing alignments...  [34.669s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.041s]
Sorting trace points...  [0.984s]
Computing alignments...  [34.856s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.295s]
Computing alignments...  [35.163s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.052s]
Sorting trace points...  [0.952s]
Computing alignments...  [34.453s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.278s]
Computing alignments...  [34.439s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.178s]
Computing alignments...  [35.823s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.448s]
Computing alignments...  [37.79s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.115s]
Computing alignments...  [38.073s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.353s]
Computing alignments...  [37.769s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.508s]
Computing alignments...  [37.705s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.424s]
Computing alignments...  [37.685s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.426s]
Computing alignments...  [37.724s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.409s]
Computing alignments...  [37.372s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [606.878s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [23.729s]
Masking reference...  [24.991s]
Initializing dictionary...  [0.063s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [26.301s]
Allocating buffers...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.355s]
Building query seed array...  [2.518s]
Computing hash join...  [4.549s]
Masking low complexity seeds...  [0.274s]
Searching alignments...  [68.313s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [9.876s]
Building query seed array...  [2.904s]
Computing hash join...  [4.507s]
Masking low complexity seeds...  [0.274s]
Searching alignments...  [45.984s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [10.972s]
Building query seed array...  [3.005s]
Computing hash join...  [4.574s]
Masking low complexity seeds...  [0.279s]
Searching alignments...  [42.289s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [8.118s]
Building query seed array...  [2.539s]
Computing hash join...  [4.537s]
Masking low complexity seeds...  [0.276s]
Searching alignments...  [36.169s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [8.449s]
Building query seed array...  [2.304s]
Computing hash join...  [4.31s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [37.143s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [9.747s]
Building query seed array...  [2.697s]
Computing hash join...  [4.297s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [30.323s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [10.859s]
Building query seed array...  [2.703s]
Computing hash join...  [4.322s]
Masking low complexity seeds...  [0.256s]
Searching alignments...  [31.613s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [8.158s]
Building query seed array...  [2.254s]
Computing hash join...  [4.303s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [28.519s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.107s]
Clearing query masking...  [1.841s]
Opening temporary output file...  [0.026s]
Computing alignments... Loading trace points...  [11.809s]
Sorting trace points...  [2.115s]
Computing alignments...  [55.608s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.12s]
Sorting trace points...  [1.885s]
Computing alignments...  [55.643s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.101s]
Sorting trace points...  [2.076s]
Computing alignments...  [55.935s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.06s]
Sorting trace points...  [2.073s]
Computing alignments...  [54.815s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.13s]
Computing alignments...  [28.678s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.066s]
Computing alignments...  [30.261s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.216s]
Computing alignments...  [30.394s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.209s]
Computing alignments...  [30.143s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.143s]
Computing alignments...  [30.171s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.142s]
Computing alignments...  [30.173s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.156s]
Computing alignments...  [30.226s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.042s]
Computing alignments...  [29.801s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
 [491.964s]
Deallocating reference...  [0.051s]
Loading reference sequences...  [0.088s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [2198.27s]
 [2198.27s]
Deallocating queries...  [0.073s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [3.815s]
 [5.152s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 19693.4s
Reported 2753925967 pairwise alignments, 2753925967 HSPs.
16526555 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C25_R2.fastp-trim.20230215.fq.gz complete: C25_R2.blastx.meganized.daa

Now MEGANizing C25_R2.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: C25_R2.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 100% (277.0s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.2s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (5,112.7s)
Total reads:       16,526,555
With hits:          16,526,555 
Alignments:      2,751,234,900
Assig. Taxonomy:    15,336,380
Assig. SEED:           117,562
Assig. EGGNOG:          60,368
Assig. GTDB:           450,713
Assig. EC:           2,618,440
Assig. INTERPRO2GO:  1,339,074
MinSupport set to: 8263
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.4s)
Min-supp. changes:       4,439
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (13.6s)
Min-supp. changes:       3,547
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (70.0s)
Binning reads Syncing
100% (0.4s)
Class. Taxonomy:            69
Class. SEED:               511
Class. EGGNOG:           1,795
Class. GTDB:                17
Class. EC:               2,418
Class. INTERPRO2GO:      8,151
Total time:  5,483s
Peak memory: 32.8 of 195.3G
MEGANization of C25_R2.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C26_R1.fastp-trim.20230215.fq.gz...
6408e745a530d46774be1786a9792ad8  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C26_R1.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C26_R1.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.34s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.712s]
Opening the output file...  [0s]
Loading query sequences...  [70.055s]
Masking queries...  [17.885s]
Algorithm: Double-indexed
Building query histograms...  [16.835s]
Loading reference sequences...  [29.665s]
Masking reference...  [32.167s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.013s]
Allocating buffers...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.242s]
Building query seed array...  [1.987s]
Computing hash join...  [5.155s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [69.214s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.193s]
Building query seed array...  [2.285s]
Computing hash join...  [5.105s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [44.08s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.364s]
Building query seed array...  [2.403s]
Computing hash join...  [5.079s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [39.809s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.184s]
Building query seed array...  [1.944s]
Computing hash join...  [5.039s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [35.437s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.23s]
Building query seed array...  [1.754s]
Computing hash join...  [4.931s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [35.81s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.988s]
Building query seed array...  [2.029s]
Computing hash join...  [4.925s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [27.722s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.004s]
Building query seed array...  [2.227s]
Computing hash join...  [4.856s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [30.055s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.878s]
Building query seed array...  [1.753s]
Computing hash join...  [4.913s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [26.802s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.58s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [11.264s]
Sorting trace points...  [2.05s]
Computing alignments...  [55.072s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.145s]
Sorting trace points...  [1.892s]
Computing alignments...  [55.281s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.106s]
Sorting trace points...  [2.039s]
Computing alignments...  [54.48s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.14s]
Sorting trace points...  [1.746s]
Computing alignments...  [54.517s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.04s]
Sorting trace points...  [1.89s]
Computing alignments...  [56.352s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.129s]
Sorting trace points...  [1.777s]
Computing alignments...  [57.171s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.699s]
Computing alignments...  [57.137s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0s]
Sorting trace points...  [1.842s]
Computing alignments...  [56.399s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0s]
 [473.561s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [34.103s]
Masking reference...  [31.142s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.18s]
Allocating buffers...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.6s]
Building query seed array...  [1.985s]
Computing hash join...  [5.013s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [68.141s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.519s]
Building query seed array...  [2.413s]
Computing hash join...  [5.069s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [42.366s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.553s]
Building query seed array...  [2.394s]
Computing hash join...  [5.155s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [37.546s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.947s]
Building query seed array...  [1.956s]
Computing hash join...  [5.073s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [34.694s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.042s]
Building query seed array...  [1.755s]
Computing hash join...  [4.853s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [34.193s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.45s]
Building query seed array...  [2.081s]
Computing hash join...  [4.836s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [27.154s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.394s]
Building query seed array...  [2.132s]
Computing hash join...  [4.935s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [29.412s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.799s]
Building query seed array...  [1.755s]
Computing hash join...  [4.917s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [25.715s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.129s]
Clearing query masking...  [1.561s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [11.179s]
Sorting trace points...  [2.163s]
Computing alignments...  [54.349s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.129s]
Sorting trace points...  [2.152s]
Computing alignments...  [54.744s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.143s]
Sorting trace points...  [2.04s]
Computing alignments...  [53.988s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.529s]
Computing alignments...  [54.292s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.122s]
Sorting trace points...  [1.624s]
Computing alignments...  [56.056s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.145s]
Sorting trace points...  [1.757s]
Computing alignments...  [56.81s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.164s]
Sorting trace points...  [2.223s]
Computing alignments...  [56.793s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0s]
Sorting trace points...  [2.143s]
Computing alignments...  [56.207s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
 [471.058s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.284s]
Masking reference...  [32.111s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [31.987s]
Allocating buffers...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.499s]
Building query seed array...  [1.991s]
Computing hash join...  [5.143s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [70.185s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.057s]
Building query seed array...  [2.273s]
Computing hash join...  [5.079s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [44.403s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.711s]
Building query seed array...  [2.431s]
Computing hash join...  [5.085s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [37.664s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.499s]
Building query seed array...  [1.93s]
Computing hash join...  [5.174s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [35.753s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.201s]
Building query seed array...  [1.784s]
Computing hash join...  [5.029s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [34.595s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.426s]
Building query seed array...  [2.141s]
Computing hash join...  [4.839s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [28.416s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.941s]
Building query seed array...  [2.217s]
Computing hash join...  [4.907s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [30.894s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.055s]
Building query seed array...  [1.778s]
Computing hash join...  [4.985s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [26.493s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.122s]
Clearing query masking...  [1.537s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [11.133s]
Sorting trace points...  [2.109s]
Computing alignments...  [54.879s]
Deallocating buffers...  [0.028s]
Loading trace points...  [1.376s]
Sorting trace points...  [1.698s]
Computing alignments...  [54.865s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.323s]
Sorting trace points...  [1.929s]
Computing alignments...  [54.075s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.115s]
Sorting trace points...  [2.141s]
Computing alignments...  [54.282s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.002s]
Sorting trace points...  [1.698s]
Computing alignments...  [56.134s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.124s]
Sorting trace points...  [2.165s]
Computing alignments...  [57.036s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.818s]
Computing alignments...  [56.86s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0s]
Sorting trace points...  [2.157s]
Computing alignments...  [56.165s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
 [473.474s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [34.571s]
Masking reference...  [31.055s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.454s]
Allocating buffers...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.188s]
Building query seed array...  [1.951s]
Computing hash join...  [5.048s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [68.201s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.086s]
Building query seed array...  [2.315s]
Computing hash join...  [5.116s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [42.813s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.254s]
Building query seed array...  [2.478s]
Computing hash join...  [5.048s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [37.985s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.339s]
Building query seed array...  [1.939s]
Computing hash join...  [5.107s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [33.952s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.129s]
Building query seed array...  [1.822s]
Computing hash join...  [4.863s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [34.661s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.417s]
Building query seed array...  [2.097s]
Computing hash join...  [4.864s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [27.604s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.977s]
Building query seed array...  [2.186s]
Computing hash join...  [4.851s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [30.79s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.912s]
Building query seed array...  [1.794s]
Computing hash join...  [4.896s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [26.388s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.555s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [12.04s]
Sorting trace points...  [2.162s]
Computing alignments...  [54.555s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.192s]
Sorting trace points...  [2.177s]
Computing alignments...  [54.668s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.114s]
Sorting trace points...  [2.101s]
Computing alignments...  [53.871s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.21s]
Sorting trace points...  [2.164s]
Computing alignments...  [54.323s]
Deallocating buffers...  [0.032s]
Loading trace points...  [0.001s]
Sorting trace points...  [2.176s]
Computing alignments...  [56.01s]
Deallocating buffers...  [0.034s]
Loading trace points...  [0.121s]
Sorting trace points...  [2.245s]
Computing alignments...  [56.92s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.071s]
Sorting trace points...  [2.126s]
Computing alignments...  [56.943s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0s]
Sorting trace points...  [1.672s]
Computing alignments...  [56.185s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0s]
 [473.35s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.497s]
Masking reference...  [30.822s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [33.05s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.782s]
Building query seed array...  [1.96s]
Computing hash join...  [5.05s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [67.732s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.617s]
Building query seed array...  [2.287s]
Computing hash join...  [5.062s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [42.44s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.862s]
Building query seed array...  [2.511s]
Computing hash join...  [5.033s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [37.682s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.041s]
Building query seed array...  [1.974s]
Computing hash join...  [5.01s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [33.65s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.209s]
Building query seed array...  [1.781s]
Computing hash join...  [4.829s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [34.836s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.278s]
Building query seed array...  [2.123s]
Computing hash join...  [4.87s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [28.361s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.589s]
Building query seed array...  [2.174s]
Computing hash join...  [4.862s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [30.373s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.016s]
Building query seed array...  [1.779s]
Computing hash join...  [4.851s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [26.091s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.551s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [11.073s]
Sorting trace points...  [2.183s]
Computing alignments...  [54.485s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.128s]
Sorting trace points...  [1.745s]
Computing alignments...  [54.57s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.82s]
Computing alignments...  [53.862s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.161s]
Sorting trace points...  [2.098s]
Computing alignments...  [54.104s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.151s]
Sorting trace points...  [2.15s]
Computing alignments...  [56.05s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0.138s]
Sorting trace points...  [1.738s]
Computing alignments...  [56.797s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.186s]
Sorting trace points...  [1.881s]
Computing alignments...  [56.614s]
Deallocating buffers...  [0.04s]
Loading trace points...  [0s]
Sorting trace points...  [1.786s]
Computing alignments...  [55.947s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0s]
 [470.029s]
Deallocating reference...  [0.064s]
Loading reference sequences...  [35.056s]
Masking reference...  [31.049s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.12s]
Allocating buffers...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.31s]
Building query seed array...  [1.95s]
Computing hash join...  [5.043s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [66.967s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.401s]
Building query seed array...  [2.291s]
Computing hash join...  [5.047s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [41.305s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.121s]
Building query seed array...  [2.568s]
Computing hash join...  [5.104s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [36.308s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.135s]
Building query seed array...  [2.006s]
Computing hash join...  [4.96s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [33.824s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.975s]
Building query seed array...  [1.835s]
Computing hash join...  [4.865s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [33.407s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.052s]
Building query seed array...  [2.095s]
Computing hash join...  [4.896s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [27.296s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.784s]
Building query seed array...  [2.203s]
Computing hash join...  [4.941s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [31.311s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.902s]
Building query seed array...  [1.746s]
Computing hash join...  [4.859s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [25.314s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.516s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [12.235s]
Sorting trace points...  [2.136s]
Computing alignments...  [54.181s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.646s]
Sorting trace points...  [1.716s]
Computing alignments...  [54.312s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.128s]
Sorting trace points...  [1.676s]
Computing alignments...  [53.678s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.337s]
Sorting trace points...  [1.816s]
Computing alignments...  [53.898s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.198s]
Sorting trace points...  [1.853s]
Computing alignments...  [55.912s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.149s]
Sorting trace points...  [1.707s]
Computing alignments...  [56.728s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.162s]
Sorting trace points...  [2.237s]
Computing alignments...  [56.754s]
Deallocating buffers...  [0.034s]
Loading trace points...  [0s]
Sorting trace points...  [1.728s]
Computing alignments...  [55.84s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0s]
 [470.37s]
Deallocating reference...  [0.064s]
Loading reference sequences...  [29.604s]
Masking reference...  [30.872s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.098s]
Allocating buffers...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.394s]
Building query seed array...  [1.969s]
Computing hash join...  [5.065s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [68.843s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.272s]
Building query seed array...  [2.246s]
Computing hash join...  [5.062s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [42.638s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.394s]
Building query seed array...  [2.376s]
Computing hash join...  [5.062s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [38.238s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.176s]
Building query seed array...  [1.984s]
Computing hash join...  [5.144s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [33.858s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.204s]
Building query seed array...  [1.824s]
Computing hash join...  [4.863s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [35.425s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.161s]
Building query seed array...  [2.092s]
Computing hash join...  [4.788s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [28.302s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.61s]
Building query seed array...  [2.204s]
Computing hash join...  [4.87s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [30.805s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.973s]
Building query seed array...  [1.788s]
Computing hash join...  [4.84s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [26.518s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.121s]
Clearing query masking...  [1.536s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [11.121s]
Sorting trace points...  [2.173s]
Computing alignments...  [54.696s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.946s]
Sorting trace points...  [2.132s]
Computing alignments...  [54.788s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.821s]
Sorting trace points...  [1.793s]
Computing alignments...  [53.929s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.131s]
Sorting trace points...  [2.064s]
Computing alignments...  [54.255s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.002s]
Sorting trace points...  [2.153s]
Computing alignments...  [56.139s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.141s]
Sorting trace points...  [2.254s]
Computing alignments...  [56.904s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.064s]
Sorting trace points...  [2.271s]
Computing alignments...  [56.945s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0s]
Sorting trace points...  [1.945s]
Computing alignments...  [56.088s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0s]
 [474.069s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [29.588s]
Masking reference...  [30.848s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.29s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.153s]
Building query seed array...  [1.957s]
Computing hash join...  [5.017s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [68.603s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.278s]
Building query seed array...  [2.301s]
Computing hash join...  [5.15s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [42.462s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.304s]
Building query seed array...  [2.492s]
Computing hash join...  [5.032s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [37.62s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.249s]
Building query seed array...  [1.951s]
Computing hash join...  [5.02s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [33.618s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.22s]
Building query seed array...  [1.808s]
Computing hash join...  [4.844s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [34.768s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.421s]
Building query seed array...  [2.144s]
Computing hash join...  [4.946s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [28.358s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.196s]
Building query seed array...  [2.118s]
Computing hash join...  [4.785s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [30.422s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.866s]
Building query seed array...  [1.849s]
Computing hash join...  [4.798s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [25.993s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.557s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [11.132s]
Sorting trace points...  [2.102s]
Computing alignments...  [54.518s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.169s]
Sorting trace points...  [1.8s]
Computing alignments...  [54.724s]
Deallocating buffers...  [0.028s]
Loading trace points...  [1.134s]
Sorting trace points...  [2.088s]
Computing alignments...  [53.926s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.122s]
Sorting trace points...  [2.095s]
Computing alignments...  [54.263s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.126s]
Sorting trace points...  [2.208s]
Computing alignments...  [56.19s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.139s]
Sorting trace points...  [1.847s]
Computing alignments...  [57.11s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.077s]
Sorting trace points...  [2.257s]
Computing alignments...  [56.996s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0s]
Sorting trace points...  [1.653s]
Computing alignments...  [56.273s]
Deallocating buffers...  [0.037s]
Loading trace points...  [0s]
 [473.257s]
Deallocating reference...  [0.072s]
Loading reference sequences...  [29.596s]
Masking reference...  [30.816s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.001s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.421s]
Building query seed array...  [1.977s]
Computing hash join...  [5.011s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [68.143s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.761s]
Building query seed array...  [2.257s]
Computing hash join...  [5.028s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [42.793s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.637s]
Building query seed array...  [2.426s]
Computing hash join...  [4.99s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [37.392s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.179s]
Building query seed array...  [1.986s]
Computing hash join...  [4.93s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [33.468s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.235s]
Building query seed array...  [1.797s]
Computing hash join...  [4.942s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [34.524s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.892s]
Building query seed array...  [2.078s]
Computing hash join...  [4.858s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [28.682s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.899s]
Building query seed array...  [2.176s]
Computing hash join...  [4.837s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [30.502s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.953s]
Building query seed array...  [1.764s]
Computing hash join...  [4.917s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [26.255s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.128s]
Clearing query masking...  [1.486s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [11.32s]
Sorting trace points...  [2.22s]
Computing alignments...  [54.459s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.122s]
Sorting trace points...  [1.848s]
Computing alignments...  [54.556s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.609s]
Sorting trace points...  [2.073s]
Computing alignments...  [53.743s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.124s]
Sorting trace points...  [1.63s]
Computing alignments...  [54.125s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.154s]
Sorting trace points...  [2.107s]
Computing alignments...  [56.042s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.139s]
Sorting trace points...  [2.142s]
Computing alignments...  [56.993s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.127s]
Sorting trace points...  [2.167s]
Computing alignments...  [56.778s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0s]
Sorting trace points...  [2.174s]
Computing alignments...  [56.166s]
Deallocating buffers...  [0.04s]
Loading trace points...  [0s]
 [472.141s]
Deallocating reference...  [0.068s]
Loading reference sequences...  [29.828s]
Masking reference...  [30.845s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.667s]
Allocating buffers...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.279s]
Building query seed array...  [1.992s]
Computing hash join...  [5.082s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [68.905s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [11.845s]
Building query seed array...  [2.345s]
Computing hash join...  [5.135s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [42.516s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.176s]
Building query seed array...  [2.422s]
Computing hash join...  [4.927s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [38.729s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.042s]
Building query seed array...  [1.921s]
Computing hash join...  [4.974s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [34.31s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.34s]
Building query seed array...  [1.838s]
Computing hash join...  [4.959s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [34.323s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.912s]
Building query seed array...  [2.044s]
Computing hash join...  [4.909s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [27.491s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.875s]
Building query seed array...  [2.198s]
Computing hash join...  [4.892s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [30.217s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.514s]
Building query seed array...  [1.728s]
Computing hash join...  [4.906s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [26.472s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.553s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [10.899s]
Sorting trace points...  [2.268s]
Computing alignments...  [54.514s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.128s]
Sorting trace points...  [2.179s]
Computing alignments...  [54.587s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.825s]
Sorting trace points...  [2.054s]
Computing alignments...  [53.795s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.137s]
Sorting trace points...  [2.136s]
Computing alignments...  [54.139s]
Deallocating buffers...  [0.035s]
Loading trace points...  [0.164s]
Sorting trace points...  [1.936s]
Computing alignments...  [56.026s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.142s]
Sorting trace points...  [1.861s]
Computing alignments...  [56.737s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.166s]
Sorting trace points...  [2.121s]
Computing alignments...  [56.748s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0s]
Sorting trace points...  [2.101s]
Computing alignments...  [56.04s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0s]
 [472.007s]
Deallocating reference...  [0.064s]
Loading reference sequences...  [29.731s]
Masking reference...  [30.891s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [33.241s]
Allocating buffers...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.374s]
Building query seed array...  [1.965s]
Computing hash join...  [5.129s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [68.579s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.624s]
Building query seed array...  [2.271s]
Computing hash join...  [5.091s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [41.571s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.159s]
Building query seed array...  [2.423s]
Computing hash join...  [4.952s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [37.42s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.257s]
Building query seed array...  [1.931s]
Computing hash join...  [5.064s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [33.178s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.475s]
Building query seed array...  [1.822s]
Computing hash join...  [4.94s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [34.021s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.429s]
Building query seed array...  [2.107s]
Computing hash join...  [4.852s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [27.675s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.053s]
Building query seed array...  [2.21s]
Computing hash join...  [4.908s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [29.813s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.177s]
Building query seed array...  [1.736s]
Computing hash join...  [4.886s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [26.035s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.13s]
Clearing query masking...  [1.467s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [11.469s]
Sorting trace points...  [2.21s]
Computing alignments...  [54.364s]
Deallocating buffers...  [0.029s]
Loading trace points...  [1.091s]
Sorting trace points...  [2.144s]
Computing alignments...  [54.673s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.125s]
Sorting trace points...  [2.056s]
Computing alignments...  [53.789s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.057s]
Sorting trace points...  [2.066s]
Computing alignments...  [54.009s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.149s]
Sorting trace points...  [1.718s]
Computing alignments...  [55.824s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.126s]
Sorting trace points...  [1.639s]
Computing alignments...  [56.745s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.212s]
Sorting trace points...  [1.938s]
Computing alignments...  [56.737s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0s]
Sorting trace points...  [2.123s]
Computing alignments...  [55.999s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0s]
 [471.588s]
Deallocating reference...  [0.063s]
Loading reference sequences...  [29.616s]
Masking reference...  [32.171s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.154s]
Allocating buffers...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.164s]
Building query seed array...  [1.951s]
Computing hash join...  [5.044s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [69.091s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.856s]
Building query seed array...  [2.34s]
Computing hash join...  [5.042s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [42.588s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.556s]
Building query seed array...  [2.502s]
Computing hash join...  [5.027s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [38.144s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.935s]
Building query seed array...  [2.01s]
Computing hash join...  [5.056s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [33.569s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.574s]
Building query seed array...  [1.817s]
Computing hash join...  [4.903s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [35.243s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.239s]
Building query seed array...  [2.149s]
Computing hash join...  [4.886s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [28.221s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.193s]
Building query seed array...  [2.175s]
Computing hash join...  [4.863s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [30.891s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.912s]
Building query seed array...  [1.742s]
Computing hash join...  [4.82s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [26.449s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.136s]
Clearing query masking...  [1.563s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [12.095s]
Sorting trace points...  [2.228s]
Computing alignments...  [54.515s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.12s]
Sorting trace points...  [2.106s]
Computing alignments...  [54.757s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.593s]
Sorting trace points...  [2.1s]
Computing alignments...  [53.905s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.107s]
Sorting trace points...  [1.794s]
Computing alignments...  [54.303s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.001s]
Sorting trace points...  [2.22s]
Computing alignments...  [56.087s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.155s]
Sorting trace points...  [2.264s]
Computing alignments...  [56.981s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.075s]
Sorting trace points...  [2.114s]
Computing alignments...  [56.862s]
Deallocating buffers...  [0.037s]
Loading trace points...  [0s]
Sorting trace points...  [2.015s]
Computing alignments...  [56.105s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0s]
 [473.861s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.406s]
Masking reference...  [30.928s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.18s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [9.839s]
Building query seed array...  [1.916s]
Computing hash join...  [5.144s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [68.756s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.256s]
Building query seed array...  [2.359s]
Computing hash join...  [5.026s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [42.059s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.954s]
Building query seed array...  [2.451s]
Computing hash join...  [5.01s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [37.948s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.02s]
Building query seed array...  [1.965s]
Computing hash join...  [4.999s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [34.184s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.753s]
Building query seed array...  [1.846s]
Computing hash join...  [5.022s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [34.038s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.492s]
Building query seed array...  [2.099s]
Computing hash join...  [4.884s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [26.908s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.986s]
Building query seed array...  [2.146s]
Computing hash join...  [4.862s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [31.518s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.333s]
Building query seed array...  [1.782s]
Computing hash join...  [4.84s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [26.694s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.133s]
Clearing query masking...  [1.575s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [11.167s]
Sorting trace points...  [2.24s]
Computing alignments...  [54.937s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.13s]
Sorting trace points...  [1.729s]
Computing alignments...  [54.681s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.244s]
Sorting trace points...  [2.001s]
Computing alignments...  [53.895s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.97s]
Computing alignments...  [54.162s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.154s]
Sorting trace points...  [2.161s]
Computing alignments...  [56.04s]
Deallocating buffers...  [0.038s]
Loading trace points...  [0.12s]
Sorting trace points...  [2.154s]
Computing alignments...  [56.786s]
Deallocating buffers...  [0.035s]
Loading trace points...  [0.192s]
Sorting trace points...  [1.83s]
Computing alignments...  [56.76s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0s]
Sorting trace points...  [1.974s]
Computing alignments...  [56.038s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0s]
 [471.683s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [23.623s]
Masking reference...  [25.075s]
Initializing dictionary...  [0.062s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [26.988s]
Allocating buffers...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.755s]
Building query seed array...  [2.007s]
Computing hash join...  [4.254s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [54.964s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [10.06s]
Building query seed array...  [2.208s]
Computing hash join...  [4.32s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [34.951s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [11.26s]
Building query seed array...  [2.415s]
Computing hash join...  [4.281s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [31.072s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [8.062s]
Building query seed array...  [1.942s]
Computing hash join...  [4.285s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [27.371s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [7.98s]
Building query seed array...  [1.846s]
Computing hash join...  [4.075s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [28.475s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [10.023s]
Building query seed array...  [2.104s]
Computing hash join...  [4.082s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [22.502s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [10.595s]
Building query seed array...  [2.164s]
Computing hash join...  [4.071s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [24.363s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [8.077s]
Building query seed array...  [1.849s]
Computing hash join...  [4.116s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [22.287s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.106s]
Clearing query masking...  [1.561s]
Opening temporary output file...  [0.02s]
Computing alignments... Loading trace points...  [9.687s]
Sorting trace points...  [1.798s]
Computing alignments...  [43.56s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.115s]
Sorting trace points...  [1.652s]
Computing alignments...  [43.564s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.122s]
Sorting trace points...  [1.355s]
Computing alignments...  [43.012s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.131s]
Sorting trace points...  [1.39s]
Computing alignments...  [43.265s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.137s]
Sorting trace points...  [1.758s]
Computing alignments...  [44.74s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.344s]
Computing alignments...  [45.448s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.169s]
Sorting trace points...  [1.834s]
Computing alignments...  [45.326s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
Sorting trace points...  [1.622s]
Computing alignments...  [44.785s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
 [377.23s]
Deallocating reference...  [0.053s]
Loading reference sequences...  [0.317s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [1685.55s]
 [1685.55s]
Deallocating queries...  [0.057s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [3.792s]
 [4.961s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 15901s
Reported 2143190674 pairwise alignments, 2143190674 HSPs.
12384802 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C26_R1.fastp-trim.20230215.fq.gz complete: C26_R1.blastx.meganized.daa

Now MEGANizing C26_R1.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: C26_R1.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 100% (256.8s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.2s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (4,016.8s)
Total reads:       12,384,802
With hits:          12,384,802 
Alignments:      2,139,155,889
Assig. Taxonomy:    11,197,904
Assig. SEED:            95,364
Assig. EGGNOG:          50,255
Assig. GTDB:           353,990
Assig. EC:           1,858,135
Assig. INTERPRO2GO:  1,064,257
MinSupport set to: 6192
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.4s)
Min-supp. changes:       4,106
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (10.3s)
Min-supp. changes:       3,151
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (31.9s)
Binning reads Syncing
100% (0.4s)
Class. Taxonomy:            69
Class. SEED:               515
Class. EGGNOG:           1,775
Class. GTDB:                19
Class. EC:               2,389
Class. INTERPRO2GO:      7,861
Total time:  4,326s
Peak memory: 29.8 of 195.3G
MEGANization of C26_R1.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C26_R2.fastp-trim.20230215.fq.gz...
3255afc294480a36010924a69df29aef  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C26_R2.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C26_R2.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.306s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.744s]
Opening the output file...  [0s]
Loading query sequences...  [70.517s]
Masking queries...  [18.111s]
Algorithm: Double-indexed
Building query histograms...  [18.513s]
Loading reference sequences...  [29.521s]
Masking reference...  [30.856s]
Initializing dictionary...  [0.08s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.296s]
Allocating buffers...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [9.943s]
Building query seed array...  [1.984s]
Computing hash join...  [5.341s]
Masking low complexity seeds...  [0.271s]
Searching alignments...  [70.406s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.326s]
Building query seed array...  [2.296s]
Computing hash join...  [5.28s]
Masking low complexity seeds...  [0.268s]
Searching alignments...  [43.376s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.242s]
Building query seed array...  [2.453s]
Computing hash join...  [5.166s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [38.745s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.765s]
Building query seed array...  [2.537s]
Computing hash join...  [5.263s]
Masking low complexity seeds...  [0.268s]
Searching alignments...  [34.729s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.449s]
Building query seed array...  [1.781s]
Computing hash join...  [5.093s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [39.677s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.737s]
Building query seed array...  [2.136s]
Computing hash join...  [5.061s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [28.533s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.769s]
Building query seed array...  [2.241s]
Computing hash join...  [5.116s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [33.899s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.042s]
Building query seed array...  [1.832s]
Computing hash join...  [5.032s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [26.816s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.122s]
Clearing query masking...  [1.545s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [10.969s]
Sorting trace points...  [2.129s]
Computing alignments...  [54.157s]
Deallocating buffers...  [0.032s]
Loading trace points...  [0.141s]
Sorting trace points...  [1.662s]
Computing alignments...  [53.665s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.159s]
Sorting trace points...  [1.677s]
Computing alignments...  [53.98s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.181s]
Sorting trace points...  [2.04s]
Computing alignments...  [53.419s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.067s]
Sorting trace points...  [2.138s]
Computing alignments...  [56.333s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.403s]
Sorting trace points...  [1.141s]
Computing alignments...  [29.165s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.089s]
Computing alignments...  [29.012s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.08s]
Computing alignments...  [28.915s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.08s]
Computing alignments...  [29.216s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.13s]
Computing alignments...  [29.222s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.093s]
Computing alignments...  [28.763s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [474.618s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [31.706s]
Masking reference...  [31.611s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.41s]
Allocating buffers...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.215s]
Building query seed array...  [2.022s]
Computing hash join...  [5.229s]
Masking low complexity seeds...  [0.268s]
Searching alignments...  [67.528s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.523s]
Building query seed array...  [2.266s]
Computing hash join...  [5.231s]
Masking low complexity seeds...  [0.266s]
Searching alignments...  [42.982s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.477s]
Building query seed array...  [2.473s]
Computing hash join...  [5.13s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [39.782s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.177s]
Building query seed array...  [1.943s]
Computing hash join...  [5.113s]
Masking low complexity seeds...  [0.266s]
Searching alignments...  [33.811s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.886s]
Building query seed array...  [1.814s]
Computing hash join...  [5.023s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [36.519s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.305s]
Building query seed array...  [2.044s]
Computing hash join...  [4.955s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [27.795s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.807s]
Building query seed array...  [2.263s]
Computing hash join...  [5.047s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [31.166s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.566s]
Building query seed array...  [1.747s]
Computing hash join...  [4.968s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [27.016s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.122s]
Clearing query masking...  [1.491s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [10.303s]
Sorting trace points...  [2.074s]
Computing alignments...  [53.645s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.181s]
Sorting trace points...  [1.685s]
Computing alignments...  [53.609s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.18s]
Sorting trace points...  [1.892s]
Computing alignments...  [53.951s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.142s]
Sorting trace points...  [1.752s]
Computing alignments...  [53.304s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.102s]
Sorting trace points...  [2.167s]
Computing alignments...  [56.196s]
Deallocating buffers...  [0.034s]
Loading trace points...  [0.102s]
Sorting trace points...  [1.141s]
Computing alignments...  [29.168s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.052s]
Sorting trace points...  [0.861s]
Computing alignments...  [29.018s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.085s]
Sorting trace points...  [0.798s]
Computing alignments...  [28.94s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.197s]
Sorting trace points...  [1.03s]
Computing alignments...  [29.284s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.101s]
Computing alignments...  [29.164s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [0.797s]
Computing alignments...  [28.777s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [472.069s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [29.69s]
Masking reference...  [30.861s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.55s]
Allocating buffers...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.388s]
Building query seed array...  [2.077s]
Computing hash join...  [5.17s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [68.25s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.153s]
Building query seed array...  [2.318s]
Computing hash join...  [5.228s]
Masking low complexity seeds...  [0.265s]
Searching alignments...  [43.835s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.352s]
Building query seed array...  [2.551s]
Computing hash join...  [5.086s]
Masking low complexity seeds...  [0.272s]
Searching alignments...  [39.661s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.981s]
Building query seed array...  [1.987s]
Computing hash join...  [5.206s]
Masking low complexity seeds...  [0.266s]
Searching alignments...  [36.499s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.209s]
Building query seed array...  [1.848s]
Computing hash join...  [5.078s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [37.451s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.25s]
Building query seed array...  [2.099s]
Computing hash join...  [4.954s]
Masking low complexity seeds...  [0.249s]
Searching alignments...  [28.322s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.885s]
Building query seed array...  [2.206s]
Computing hash join...  [4.947s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [31.626s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.17s]
Building query seed array...  [1.746s]
Computing hash join...  [5.087s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [26.807s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.102s]
Clearing query masking...  [1.496s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [11.22s]
Sorting trace points...  [2.058s]
Computing alignments...  [53.549s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.072s]
Sorting trace points...  [2.146s]
Computing alignments...  [53.486s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.149s]
Sorting trace points...  [2.054s]
Computing alignments...  [53.914s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.165s]
Sorting trace points...  [1.997s]
Computing alignments...  [53.434s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.078s]
Sorting trace points...  [2.16s]
Computing alignments...  [56.209s]
Deallocating buffers...  [0.035s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.029s]
Computing alignments...  [29.106s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.112s]
Computing alignments...  [28.985s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.082s]
Computing alignments...  [28.902s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.077s]
Sorting trace points...  [0.893s]
Computing alignments...  [29.114s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.002s]
Computing alignments...  [29.062s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.06s]
Computing alignments...  [28.675s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [473.38s]
Deallocating reference...  [0.068s]
Loading reference sequences...  [29.656s]
Masking reference...  [30.855s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.951s]
Allocating buffers...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.405s]
Building query seed array...  [1.968s]
Computing hash join...  [5.169s]
Masking low complexity seeds...  [0.267s]
Searching alignments...  [67.625s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.769s]
Building query seed array...  [2.321s]
Computing hash join...  [5.101s]
Masking low complexity seeds...  [0.273s]
Searching alignments...  [44.566s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.492s]
Building query seed array...  [2.465s]
Computing hash join...  [5.199s]
Masking low complexity seeds...  [0.265s]
Searching alignments...  [39.827s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.912s]
Building query seed array...  [2.049s]
Computing hash join...  [5.296s]
Masking low complexity seeds...  [0.276s]
Searching alignments...  [36.408s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.257s]
Building query seed array...  [1.884s]
Computing hash join...  [5.052s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [37.604s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.351s]
Building query seed array...  [2.109s]
Computing hash join...  [4.954s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [28.39s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.2s]
Building query seed array...  [2.149s]
Computing hash join...  [4.942s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [31.075s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.863s]
Building query seed array...  [1.72s]
Computing hash join...  [5.05s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [26.405s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.129s]
Clearing query masking...  [1.547s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [11.053s]
Sorting trace points...  [2.14s]
Computing alignments...  [53.718s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.54s]
Computing alignments...  [53.653s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.124s]
Sorting trace points...  [1.649s]
Computing alignments...  [54.056s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.134s]
Sorting trace points...  [1.917s]
Computing alignments...  [53.293s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.782s]
Computing alignments...  [56.146s]
Deallocating buffers...  [0.037s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.008s]
Computing alignments...  [29.098s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.099s]
Computing alignments...  [28.962s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.089s]
Sorting trace points...  [1.119s]
Computing alignments...  [28.937s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.016s]
Computing alignments...  [29.14s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.088s]
Sorting trace points...  [1.104s]
Computing alignments...  [29.205s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.085s]
Computing alignments...  [28.769s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [472.605s]
Deallocating reference...  [0.063s]
Loading reference sequences...  [29.636s]
Masking reference...  [30.836s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [33.23s]
Allocating buffers...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.242s]
Building query seed array...  [2.002s]
Computing hash join...  [5.158s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [67.671s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.392s]
Building query seed array...  [2.311s]
Computing hash join...  [5.227s]
Masking low complexity seeds...  [0.265s]
Searching alignments...  [43.441s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.386s]
Building query seed array...  [2.392s]
Computing hash join...  [5.083s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [39.088s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.124s]
Building query seed array...  [1.958s]
Computing hash join...  [5.112s]
Masking low complexity seeds...  [0.271s]
Searching alignments...  [34.922s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.603s]
Building query seed array...  [1.821s]
Computing hash join...  [4.995s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [36.949s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.185s]
Building query seed array...  [2.106s]
Computing hash join...  [4.924s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [28.893s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.523s]
Building query seed array...  [2.177s]
Computing hash join...  [5.059s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [30.734s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.223s]
Building query seed array...  [1.779s]
Computing hash join...  [5.001s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [26.506s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.555s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [10.204s]
Sorting trace points...  [2.222s]
Computing alignments...  [53.555s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.143s]
Sorting trace points...  [2.09s]
Computing alignments...  [53.459s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.13s]
Sorting trace points...  [2.009s]
Computing alignments...  [53.876s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.155s]
Sorting trace points...  [1.988s]
Computing alignments...  [53.236s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.78s]
Computing alignments...  [56.006s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.088s]
Computing alignments...  [29.08s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.101s]
Computing alignments...  [28.876s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.096s]
Computing alignments...  [28.84s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.07s]
Computing alignments...  [29.062s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.075s]
Sorting trace points...  [0.863s]
Computing alignments...  [29.172s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.091s]
Computing alignments...  [28.716s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0s]
 [471.685s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [29.419s]
Masking reference...  [32.115s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.421s]
Allocating buffers...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.302s]
Building query seed array...  [1.968s]
Computing hash join...  [5.153s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [65.26s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.865s]
Building query seed array...  [2.328s]
Computing hash join...  [5.267s]
Masking low complexity seeds...  [0.269s]
Searching alignments...  [43.297s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.748s]
Building query seed array...  [2.382s]
Computing hash join...  [5.166s]
Masking low complexity seeds...  [0.27s]
Searching alignments...  [38.204s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.654s]
Building query seed array...  [1.975s]
Computing hash join...  [5.193s]
Masking low complexity seeds...  [0.27s]
Searching alignments...  [33.847s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.037s]
Building query seed array...  [1.832s]
Computing hash join...  [5.029s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [35.531s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.447s]
Building query seed array...  [2.122s]
Computing hash join...  [5.056s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [28.375s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.412s]
Building query seed array...  [2.159s]
Computing hash join...  [4.991s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [30.472s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.266s]
Building query seed array...  [1.75s]
Computing hash join...  [5.018s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [25.481s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.122s]
Clearing query masking...  [1.537s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [11.664s]
Sorting trace points...  [2.176s]
Computing alignments...  [53.238s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.145s]
Sorting trace points...  [1.971s]
Computing alignments...  [53.063s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.107s]
Sorting trace points...  [1.964s]
Computing alignments...  [53.472s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.163s]
Sorting trace points...  [2.1s]
Computing alignments...  [52.821s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.72s]
Computing alignments...  [55.791s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.119s]
Computing alignments...  [28.904s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.096s]
Computing alignments...  [28.79s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.054s]
Computing alignments...  [28.728s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.092s]
Sorting trace points...  [1.13s]
Computing alignments...  [28.989s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.094s]
Computing alignments...  [28.938s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [0.988s]
Computing alignments...  [28.508s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0s]
 [470.434s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [32.091s]
Masking reference...  [32.151s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.279s]
Allocating buffers...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.184s]
Building query seed array...  [1.97s]
Computing hash join...  [5.146s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [68.217s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.311s]
Building query seed array...  [2.256s]
Computing hash join...  [5.184s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [43.591s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.294s]
Building query seed array...  [2.354s]
Computing hash join...  [5.054s]
Masking low complexity seeds...  [0.269s]
Searching alignments...  [38.197s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.894s]
Building query seed array...  [1.971s]
Computing hash join...  [5.19s]
Masking low complexity seeds...  [0.271s]
Searching alignments...  [33.82s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.247s]
Building query seed array...  [1.76s]
Computing hash join...  [5.109s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [38.328s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.189s]
Building query seed array...  [2.051s]
Computing hash join...  [4.913s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [29.114s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.478s]
Building query seed array...  [2.219s]
Computing hash join...  [4.991s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [31.513s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.79s]
Building query seed array...  [1.783s]
Computing hash join...  [5.031s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [26.475s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.132s]
Clearing query masking...  [1.574s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [10.443s]
Sorting trace points...  [2.111s]
Computing alignments...  [53.565s]
Deallocating buffers...  [0.039s]
Loading trace points...  [0.163s]
Sorting trace points...  [1.786s]
Computing alignments...  [53.569s]
Deallocating buffers...  [0.027s]
Loading trace points...  [1.144s]
Sorting trace points...  [1.7s]
Computing alignments...  [54.042s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.138s]
Sorting trace points...  [1.657s]
Computing alignments...  [53.314s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.064s]
Sorting trace points...  [2.001s]
Computing alignments...  [56.23s]
Deallocating buffers...  [0.038s]
Loading trace points...  [0.088s]
Sorting trace points...  [1.098s]
Computing alignments...  [29.111s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.14s]
Computing alignments...  [28.986s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.107s]
Computing alignments...  [28.954s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.11s]
Computing alignments...  [29.124s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.118s]
Computing alignments...  [29.085s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.093s]
Computing alignments...  [28.729s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0s]
 [473.258s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [31.656s]
Masking reference...  [31.974s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [31.967s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.061s]
Building query seed array...  [1.998s]
Computing hash join...  [5.18s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [68.201s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.235s]
Building query seed array...  [2.291s]
Computing hash join...  [5.17s]
Masking low complexity seeds...  [0.265s]
Searching alignments...  [42.641s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.492s]
Building query seed array...  [2.373s]
Computing hash join...  [5.196s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [38.716s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.288s]
Building query seed array...  [1.925s]
Computing hash join...  [5.202s]
Masking low complexity seeds...  [0.266s]
Searching alignments...  [33.567s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.023s]
Building query seed array...  [1.806s]
Computing hash join...  [4.984s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [35.911s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.191s]
Building query seed array...  [2.108s]
Computing hash join...  [4.998s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [28.834s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.61s]
Building query seed array...  [2.339s]
Computing hash join...  [4.972s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [32.65s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.906s]
Building query seed array...  [1.784s]
Computing hash join...  [4.929s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [27.083s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.121s]
Clearing query masking...  [1.549s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [11.033s]
Sorting trace points...  [2.052s]
Computing alignments...  [53.591s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.14s]
Sorting trace points...  [2.121s]
Computing alignments...  [53.516s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.153s]
Sorting trace points...  [1.697s]
Computing alignments...  [53.961s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.159s]
Sorting trace points...  [2.009s]
Computing alignments...  [53.516s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.508s]
Sorting trace points...  [1.798s]
Computing alignments...  [56.303s]
Deallocating buffers...  [0.037s]
Loading trace points...  [0.866s]
Sorting trace points...  [1.097s]
Computing alignments...  [29.176s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.143s]
Computing alignments...  [29.011s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.049s]
Computing alignments...  [28.927s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.137s]
Computing alignments...  [29.182s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.106s]
Computing alignments...  [29.194s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.105s]
Computing alignments...  [28.781s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [474.952s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [31.859s]
Masking reference...  [32.129s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.552s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [9.965s]
Building query seed array...  [1.998s]
Computing hash join...  [5.177s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [66.574s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.027s]
Building query seed array...  [2.336s]
Computing hash join...  [5.105s]
Masking low complexity seeds...  [0.269s]
Searching alignments...  [42.426s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.929s]
Building query seed array...  [2.469s]
Computing hash join...  [5.164s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [38.576s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.16s]
Building query seed array...  [1.923s]
Computing hash join...  [5.177s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [34.203s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.125s]
Building query seed array...  [1.771s]
Computing hash join...  [5.013s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [37.279s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.411s]
Building query seed array...  [2.074s]
Computing hash join...  [4.958s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [28.142s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.221s]
Building query seed array...  [2.206s]
Computing hash join...  [4.967s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [30.924s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.2s]
Building query seed array...  [1.881s]
Computing hash join...  [4.961s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [26.62s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.52s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [10.987s]
Sorting trace points...  [2.027s]
Computing alignments...  [54.095s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.147s]
Sorting trace points...  [1.719s]
Computing alignments...  [53.518s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.127s]
Sorting trace points...  [2.015s]
Computing alignments...  [54.003s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0.169s]
Sorting trace points...  [1.605s]
Computing alignments...  [53.473s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.98s]
Computing alignments...  [56.429s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.122s]
Computing alignments...  [29.228s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.105s]
Sorting trace points...  [1.064s]
Computing alignments...  [29.001s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.057s]
Sorting trace points...  [0.908s]
Computing alignments...  [28.948s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.081s]
Computing alignments...  [29.159s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.064s]
Sorting trace points...  [0.932s]
Computing alignments...  [29.294s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.085s]
Computing alignments...  [28.715s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0s]
 [473.58s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [29.573s]
Masking reference...  [30.836s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.907s]
Allocating buffers...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.073s]
Building query seed array...  [1.953s]
Computing hash join...  [5.142s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [67.663s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.372s]
Building query seed array...  [2.353s]
Computing hash join...  [5.19s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [43.717s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.228s]
Building query seed array...  [2.443s]
Computing hash join...  [5.109s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [38.948s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.255s]
Building query seed array...  [1.989s]
Computing hash join...  [5.221s]
Masking low complexity seeds...  [0.277s]
Searching alignments...  [34.206s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.595s]
Building query seed array...  [1.782s]
Computing hash join...  [4.985s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [37.843s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.511s]
Building query seed array...  [2.107s]
Computing hash join...  [4.926s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [28.155s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.507s]
Building query seed array...  [2.142s]
Computing hash join...  [5.031s]
Masking low complexity seeds...  [0.267s]
Searching alignments...  [31.483s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.676s]
Building query seed array...  [1.754s]
Computing hash join...  [4.946s]
Masking low complexity seeds...  [0.256s]
Searching alignments...  [26.719s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.122s]
Clearing query masking...  [1.54s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [10.263s]
Sorting trace points...  [2.115s]
Computing alignments...  [53.691s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.132s]
Sorting trace points...  [2.04s]
Computing alignments...  [53.744s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.113s]
Sorting trace points...  [2.056s]
Computing alignments...  [54.103s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.174s]
Sorting trace points...  [1.841s]
Computing alignments...  [53.54s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.091s]
Sorting trace points...  [1.758s]
Computing alignments...  [56.376s]
Deallocating buffers...  [0.036s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.108s]
Computing alignments...  [29.188s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.112s]
Computing alignments...  [29.114s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.005s]
Computing alignments...  [28.951s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [0.93s]
Computing alignments...  [29.193s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.114s]
Computing alignments...  [29.15s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.095s]
Computing alignments...  [28.67s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [473.334s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.748s]
Masking reference...  [30.846s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.006s]
Building reference histograms...  [32.885s]
Allocating buffers...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.172s]
Building query seed array...  [2.07s]
Computing hash join...  [5.146s]
Masking low complexity seeds...  [0.267s]
Searching alignments...  [65.279s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.655s]
Building query seed array...  [2.343s]
Computing hash join...  [5.165s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [42.413s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.493s]
Building query seed array...  [2.379s]
Computing hash join...  [5.14s]
Masking low complexity seeds...  [0.259s]
Searching alignments...  [39.202s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.8s]
Building query seed array...  [1.933s]
Computing hash join...  [5.213s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [35.136s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.2s]
Building query seed array...  [1.841s]
Computing hash join...  [4.98s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [36.583s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.359s]
Building query seed array...  [2.103s]
Computing hash join...  [4.958s]
Masking low complexity seeds...  [0.259s]
Searching alignments...  [28.357s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.259s]
Building query seed array...  [2.266s]
Computing hash join...  [5.022s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [30.926s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.858s]
Building query seed array...  [1.761s]
Computing hash join...  [4.995s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [26.293s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.582s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [10.971s]
Sorting trace points...  [2.113s]
Computing alignments...  [53.32s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.119s]
Sorting trace points...  [2.002s]
Computing alignments...  [53.223s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.125s]
Sorting trace points...  [2.013s]
Computing alignments...  [53.701s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.136s]
Sorting trace points...  [1.794s]
Computing alignments...  [53.242s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.116s]
Sorting trace points...  [1.773s]
Computing alignments...  [55.945s]
Deallocating buffers...  [0.034s]
Loading trace points...  [0.06s]
Sorting trace points...  [0.884s]
Computing alignments...  [28.997s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.126s]
Computing alignments...  [28.825s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.062s]
Sorting trace points...  [0.936s]
Computing alignments...  [28.856s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.096s]
Computing alignments...  [29.126s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.109s]
Computing alignments...  [29.129s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0s]
Sorting trace points...  [1.049s]
Computing alignments...  [28.654s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [471.029s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.677s]
Masking reference...  [32.153s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.006s]
Building reference histograms...  [31.873s]
Allocating buffers...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.649s]
Building query seed array...  [2.049s]
Computing hash join...  [5.228s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [67.173s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.292s]
Building query seed array...  [2.252s]
Computing hash join...  [5.185s]
Masking low complexity seeds...  [0.272s]
Searching alignments...  [44.564s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.206s]
Building query seed array...  [2.489s]
Computing hash join...  [5.162s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [38.878s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.989s]
Building query seed array...  [2.01s]
Computing hash join...  [5.179s]
Masking low complexity seeds...  [0.274s]
Searching alignments...  [35.124s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.181s]
Building query seed array...  [1.855s]
Computing hash join...  [4.993s]
Masking low complexity seeds...  [0.269s]
Searching alignments...  [37.453s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.551s]
Building query seed array...  [2.152s]
Computing hash join...  [4.934s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [27.754s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.206s]
Building query seed array...  [2.21s]
Computing hash join...  [4.942s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [31.893s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.107s]
Building query seed array...  [1.755s]
Computing hash join...  [5.015s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [26.934s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.121s]
Clearing query masking...  [1.541s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [11.133s]
Sorting trace points...  [2.1s]
Computing alignments...  [53.557s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.747s]
Computing alignments...  [53.623s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.129s]
Sorting trace points...  [1.737s]
Computing alignments...  [54.095s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.13s]
Sorting trace points...  [2.033s]
Computing alignments...  [53.449s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.067s]
Sorting trace points...  [2.165s]
Computing alignments...  [56.582s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.042s]
Computing alignments...  [29.243s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.123s]
Computing alignments...  [29.048s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.099s]
Computing alignments...  [28.965s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.002s]
Sorting trace points...  [1.041s]
Computing alignments...  [29.219s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.098s]
Computing alignments...  [29.24s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0s]
Sorting trace points...  [1.094s]
Computing alignments...  [28.714s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0s]
 [474.242s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [31.738s]
Masking reference...  [30.954s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.006s]
Building reference histograms...  [32.596s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.15s]
Building query seed array...  [2.214s]
Computing hash join...  [5.303s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [68.357s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.454s]
Building query seed array...  [2.327s]
Computing hash join...  [5.27s]
Masking low complexity seeds...  [0.266s]
Searching alignments...  [45.282s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.068s]
Building query seed array...  [2.43s]
Computing hash join...  [5.148s]
Masking low complexity seeds...  [0.273s]
Searching alignments...  [39.024s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.043s]
Building query seed array...  [1.98s]
Computing hash join...  [5.23s]
Masking low complexity seeds...  [0.268s]
Searching alignments...  [36.209s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.18s]
Building query seed array...  [1.864s]
Computing hash join...  [4.978s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [36.944s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.785s]
Building query seed array...  [2.142s]
Computing hash join...  [4.951s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [27.952s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.604s]
Building query seed array...  [2.16s]
Computing hash join...  [4.949s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [31.807s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.95s]
Building query seed array...  [1.774s]
Computing hash join...  [5.051s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [26.557s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.122s]
Clearing query masking...  [1.535s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [10.806s]
Sorting trace points...  [2.127s]
Computing alignments...  [53.497s]
Deallocating buffers...  [0.023s]
Loading trace points...  [1.123s]
Sorting trace points...  [2.095s]
Computing alignments...  [53.632s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.141s]
Sorting trace points...  [2.093s]
Computing alignments...  [54.011s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.167s]
Sorting trace points...  [1.624s]
Computing alignments...  [53.241s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.65s]
Computing alignments...  [56.004s]
Deallocating buffers...  [0.042s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.036s]
Computing alignments...  [29.111s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.063s]
Sorting trace points...  [0.823s]
Computing alignments...  [28.967s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.059s]
Sorting trace points...  [0.945s]
Computing alignments...  [28.787s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.102s]
Computing alignments...  [29.083s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.103s]
Computing alignments...  [29.143s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.081s]
Computing alignments...  [28.767s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0s]
 [472.896s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [23.789s]
Masking reference...  [25.979s]
Initializing dictionary...  [0.063s]
Initializing temporary storage...  [0.005s]
Building reference histograms...  [26.686s]
Allocating buffers...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.328s]
Building query seed array...  [1.987s]
Computing hash join...  [4.345s]
Masking low complexity seeds...  [0.256s]
Searching alignments...  [52.79s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [9.908s]
Building query seed array...  [2.286s]
Computing hash join...  [4.441s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [34.565s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [11.113s]
Building query seed array...  [2.501s]
Computing hash join...  [4.319s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [30.936s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [8.164s]
Building query seed array...  [1.895s]
Computing hash join...  [4.357s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [27.805s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [8.267s]
Building query seed array...  [1.858s]
Computing hash join...  [4.108s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [29.759s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [10.012s]
Building query seed array...  [2.141s]
Computing hash join...  [4.169s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [23.404s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [10.874s]
Building query seed array...  [2.161s]
Computing hash join...  [4.143s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [25.077s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [8.279s]
Building query seed array...  [1.827s]
Computing hash join...  [4.124s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [21.916s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.107s]
Clearing query masking...  [1.482s]
Opening temporary output file...  [0.014s]
Computing alignments... Loading trace points...  [9.108s]
Sorting trace points...  [1.725s]
Computing alignments...  [42.868s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.105s]
Sorting trace points...  [1.548s]
Computing alignments...  [42.705s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.723s]
Computing alignments...  [43.022s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.142s]
Sorting trace points...  [1.349s]
Computing alignments...  [42.39s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.152s]
Sorting trace points...  [1.486s]
Computing alignments...  [45.027s]
Deallocating buffers...  [0.032s]
Loading trace points...  [0.234s]
Sorting trace points...  [1.793s]
Computing alignments...  [46.23s]
Deallocating buffers...  [0.025s]
Loading trace points...  [1.03s]
Sorting trace points...  [1.67s]
Computing alignments...  [46.248s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [1.754s]
Computing alignments...  [45.746s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
 [378.406s]
Deallocating reference...  [0.048s]
Loading reference sequences...  [0.111s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [1685.77s]
 [1685.77s]
Deallocating queries...  [0.056s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [3.925s]
 [5.049s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 16010.3s
Reported 2094230460 pairwise alignments, 2094230460 HSPs.
12690817 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C26_R2.fastp-trim.20230215.fq.gz complete: C26_R2.blastx.meganized.daa

Now MEGANizing C26_R2.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: C26_R2.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 100% (222.0s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.3s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (3,869.1s)
Total reads:       12,690,817
With hits:          12,690,817 
Alignments:      2,091,289,309
Assig. Taxonomy:    11,440,879
Assig. SEED:            91,400
Assig. EGGNOG:          49,679
Assig. GTDB:           346,035
Assig. EC:           1,892,082
Assig. INTERPRO2GO:  1,066,313
MinSupport set to: 6345
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.4s)
Min-supp. changes:       4,115
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (10.4s)
Min-supp. changes:       3,252
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (25.6s)
Binning reads Syncing
100% (0.4s)
Class. Taxonomy:            67
Class. SEED:               512
Class. EGGNOG:           1,764
Class. GTDB:                17
Class. EC:               2,399
Class. INTERPRO2GO:      7,875
Total time:  4,137s
Peak memory: 36.5 of 195.3G
MEGANization of C26_R2.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C27_R1.fastp-trim.20230215.fq.gz...
9576ce5485db608fe0167fda783abc3b  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C27_R1.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C27_R1.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.299s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.713s]
Opening the output file...  [0s]
Loading query sequences...  [75.13s]
Masking queries...  [19.457s]
Algorithm: Double-indexed
Building query histograms...  [18.543s]
Loading reference sequences...  [29.371s]
Masking reference...  [32.087s]
Initializing dictionary...  [0.08s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.87s]
Allocating buffers...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.683s]
Building query seed array...  [2.131s]
Computing hash join...  [5.285s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [79.261s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.34s]
Building query seed array...  [2.511s]
Computing hash join...  [5.142s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [49.18s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.719s]
Building query seed array...  [2.655s]
Computing hash join...  [5.153s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [44.039s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.829s]
Building query seed array...  [2.098s]
Computing hash join...  [5.182s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [40.045s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.206s]
Building query seed array...  [1.945s]
Computing hash join...  [4.944s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [39.821s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.397s]
Building query seed array...  [2.244s]
Computing hash join...  [4.996s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [31.102s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.498s]
Building query seed array...  [2.345s]
Computing hash join...  [4.865s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [34.934s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.982s]
Building query seed array...  [1.938s]
Computing hash join...  [4.989s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [29.68s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.131s]
Clearing query masking...  [1.628s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.349s]
Sorting trace points...  [1.236s]
Computing alignments...  [30.93s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.194s]
Computing alignments...  [30.779s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.123s]
Computing alignments...  [30.836s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.142s]
Computing alignments...  [31.472s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.035s]
Computing alignments...  [30.852s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.175s]
Computing alignments...  [31.138s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.153s]
Computing alignments...  [31.025s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.146s]
Computing alignments...  [30.447s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.075s]
Sorting trace points...  [0.938s]
Computing alignments...  [31.486s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.197s]
Computing alignments...  [31.891s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.225s]
Computing alignments...  [31.993s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.024s]
Computing alignments...  [32.092s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.235s]
Computing alignments...  [32.14s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.047s]
Computing alignments...  [32.226s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.074s]
Sorting trace points...  [0.932s]
Computing alignments...  [31.993s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.09s]
Computing alignments...  [32.316s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
 [529.235s]
Deallocating reference...  [0.078s]
Loading reference sequences...  [29.607s]
Masking reference...  [30.92s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.588s]
Allocating buffers...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.262s]
Building query seed array...  [2.154s]
Computing hash join...  [5.215s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [76.927s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.411s]
Building query seed array...  [2.477s]
Computing hash join...  [5.095s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [48.16s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [14.329s]
Building query seed array...  [2.516s]
Computing hash join...  [5.163s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [42.961s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.886s]
Building query seed array...  [2.153s]
Computing hash join...  [5.085s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [37.628s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.278s]
Building query seed array...  [1.979s]
Computing hash join...  [5.004s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [38.968s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.17s]
Building query seed array...  [2.261s]
Computing hash join...  [4.867s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [30.718s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.109s]
Building query seed array...  [2.435s]
Computing hash join...  [4.875s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [35.654s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.63s]
Building query seed array...  [1.919s]
Computing hash join...  [5.026s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [30.151s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.609s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.268s]
Sorting trace points...  [1.217s]
Computing alignments...  [30.837s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.088s]
Sorting trace points...  [0.985s]
Computing alignments...  [30.684s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.071s]
Sorting trace points...  [0.901s]
Computing alignments...  [30.895s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.154s]
Computing alignments...  [31.261s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.213s]
Computing alignments...  [30.764s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.146s]
Sorting trace points...  [1.169s]
Computing alignments...  [31.112s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.227s]
Computing alignments...  [30.944s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.09s]
Sorting trace points...  [1.154s]
Computing alignments...  [30.399s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.116s]
Sorting trace points...  [0.909s]
Computing alignments...  [31.317s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.217s]
Computing alignments...  [31.72s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.197s]
Sorting trace points...  [1.013s]
Computing alignments...  [31.742s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.044s]
Computing alignments...  [32.025s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.139s]
Computing alignments...  [32.014s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.071s]
Sorting trace points...  [0.908s]
Computing alignments...  [32.108s]
Deallocating buffers...  [0.016s]
Loading trace points...  [1.122s]
Sorting trace points...  [1.229s]
Computing alignments...  [31.872s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [0.928s]
Computing alignments...  [32.14s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [528.057s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [33.619s]
Masking reference...  [31.375s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.352s]
Allocating buffers...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.32s]
Building query seed array...  [2.161s]
Computing hash join...  [5.201s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [81.453s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.494s]
Building query seed array...  [2.423s]
Computing hash join...  [5.212s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [50.754s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.744s]
Building query seed array...  [2.603s]
Computing hash join...  [5.121s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [44.009s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.163s]
Building query seed array...  [2.147s]
Computing hash join...  [5.144s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [39.94s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.122s]
Building query seed array...  [1.892s]
Computing hash join...  [5.061s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [40.312s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.005s]
Building query seed array...  [2.223s]
Computing hash join...  [5.082s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [31.782s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.296s]
Building query seed array...  [2.306s]
Computing hash join...  [4.908s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [34.986s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.693s]
Building query seed array...  [1.955s]
Computing hash join...  [4.948s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [31.448s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.122s]
Clearing query masking...  [1.586s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.284s]
Sorting trace points...  [1.224s]
Computing alignments...  [30.706s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.147s]
Computing alignments...  [30.618s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.227s]
Sorting trace points...  [1.041s]
Computing alignments...  [30.726s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.153s]
Computing alignments...  [30.891s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.158s]
Computing alignments...  [30.784s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.064s]
Computing alignments...  [31.227s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.161s]
Computing alignments...  [30.893s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.181s]
Computing alignments...  [30.363s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.015s]
Computing alignments...  [31.335s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.202s]
Computing alignments...  [31.779s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.229s]
Computing alignments...  [31.775s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.189s]
Computing alignments...  [31.92s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.244s]
Computing alignments...  [31.925s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.155s]
Computing alignments...  [32.079s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.088s]
Sorting trace points...  [1.193s]
Computing alignments...  [31.97s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.18s]
Computing alignments...  [32.092s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [527.434s]
Deallocating reference...  [0.075s]
Loading reference sequences...  [34.498s]
Masking reference...  [31.533s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.351s]
Allocating buffers...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.287s]
Building query seed array...  [2.118s]
Computing hash join...  [5.148s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [78.013s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.648s]
Building query seed array...  [2.596s]
Computing hash join...  [5.127s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [50.987s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.762s]
Building query seed array...  [2.71s]
Computing hash join...  [5.072s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [44.376s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.19s]
Building query seed array...  [2.124s]
Computing hash join...  [5.249s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [39.061s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.015s]
Building query seed array...  [1.923s]
Computing hash join...  [5.012s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [39.335s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.279s]
Building query seed array...  [2.214s]
Computing hash join...  [4.925s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [31.061s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.148s]
Building query seed array...  [2.348s]
Computing hash join...  [4.882s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [34.46s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.611s]
Building query seed array...  [1.911s]
Computing hash join...  [4.982s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [29.35s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.127s]
Clearing query masking...  [1.624s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.23s]
Sorting trace points...  [1.237s]
Computing alignments...  [30.633s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.142s]
Computing alignments...  [30.685s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.086s]
Sorting trace points...  [0.885s]
Computing alignments...  [30.872s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.174s]
Computing alignments...  [30.964s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.053s]
Sorting trace points...  [0.858s]
Computing alignments...  [30.835s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.179s]
Computing alignments...  [31.182s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.181s]
Computing alignments...  [31.06s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.089s]
Sorting trace points...  [1.008s]
Computing alignments...  [30.441s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.049s]
Sorting trace points...  [0.911s]
Computing alignments...  [31.422s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.192s]
Computing alignments...  [31.868s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.05s]
Sorting trace points...  [0.956s]
Computing alignments...  [31.954s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.216s]
Computing alignments...  [32.097s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.07s]
Sorting trace points...  [0.942s]
Computing alignments...  [32.134s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.251s]
Computing alignments...  [32.163s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.064s]
Sorting trace points...  [0.972s]
Computing alignments...  [32.091s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [0.969s]
Computing alignments...  [32.262s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [528.351s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [29.776s]
Masking reference...  [30.846s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.428s]
Allocating buffers...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.133s]
Building query seed array...  [2.114s]
Computing hash join...  [5.199s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [78.183s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.632s]
Building query seed array...  [2.342s]
Computing hash join...  [5.361s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [48.925s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.339s]
Building query seed array...  [2.585s]
Computing hash join...  [5.107s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [44.748s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.912s]
Building query seed array...  [2.069s]
Computing hash join...  [5.11s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [38.74s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.38s]
Building query seed array...  [1.896s]
Computing hash join...  [4.877s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [38.699s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.09s]
Building query seed array...  [2.227s]
Computing hash join...  [4.93s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [30.668s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.248s]
Building query seed array...  [2.368s]
Computing hash join...  [4.963s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [34.58s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.128s]
Building query seed array...  [1.87s]
Computing hash join...  [4.903s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [29.358s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.127s]
Clearing query masking...  [1.514s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.048s]
Sorting trace points...  [1.203s]
Computing alignments...  [30.667s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.119s]
Computing alignments...  [30.554s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.097s]
Sorting trace points...  [1.126s]
Computing alignments...  [30.643s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.087s]
Sorting trace points...  [1.066s]
Computing alignments...  [30.726s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.046s]
Sorting trace points...  [0.943s]
Computing alignments...  [30.663s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.16s]
Computing alignments...  [30.964s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.204s]
Computing alignments...  [30.857s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.147s]
Computing alignments...  [30.215s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.156s]
Computing alignments...  [31.197s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.224s]
Computing alignments...  [31.627s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.183s]
Computing alignments...  [31.62s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.096s]
Computing alignments...  [31.754s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.143s]
Computing alignments...  [31.82s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.142s]
Computing alignments...  [32.428s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.082s]
Sorting trace points...  [0.976s]
Computing alignments...  [31.702s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.078s]
Computing alignments...  [31.948s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [524.653s]
Deallocating reference...  [0.074s]
Loading reference sequences...  [29.728s]
Masking reference...  [32.08s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.042s]
Allocating buffers...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.177s]
Building query seed array...  [2.141s]
Computing hash join...  [5.111s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [76.93s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.427s]
Building query seed array...  [2.564s]
Computing hash join...  [5.18s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [50.185s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.623s]
Building query seed array...  [2.616s]
Computing hash join...  [5.057s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [42.371s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.912s]
Building query seed array...  [2.125s]
Computing hash join...  [5.101s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [38.139s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.014s]
Building query seed array...  [1.96s]
Computing hash join...  [4.935s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [38.359s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.179s]
Building query seed array...  [2.29s]
Computing hash join...  [4.891s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [31.846s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.287s]
Building query seed array...  [2.373s]
Computing hash join...  [4.892s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [34.636s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.879s]
Building query seed array...  [1.996s]
Computing hash join...  [4.924s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [30.182s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.137s]
Clearing query masking...  [1.6s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.103s]
Sorting trace points...  [1.236s]
Computing alignments...  [30.455s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.144s]
Sorting trace points...  [1.169s]
Computing alignments...  [31.83s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.161s]
Computing alignments...  [30.564s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.093s]
Sorting trace points...  [1.073s]
Computing alignments...  [30.599s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.163s]
Computing alignments...  [30.445s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.235s]
Sorting trace points...  [1.183s]
Computing alignments...  [30.745s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.085s]
Sorting trace points...  [1.085s]
Computing alignments...  [30.68s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.089s]
Sorting trace points...  [0.987s]
Computing alignments...  [30.011s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.125s]
Sorting trace points...  [1.185s]
Computing alignments...  [31.02s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.216s]
Computing alignments...  [31.425s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.184s]
Computing alignments...  [31.493s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.061s]
Sorting trace points...  [0.983s]
Computing alignments...  [31.665s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.197s]
Computing alignments...  [31.612s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.111s]
Computing alignments...  [31.755s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.216s]
Computing alignments...  [31.525s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.176s]
Computing alignments...  [31.756s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
 [523.475s]
Deallocating reference...  [0.074s]
Loading reference sequences...  [30.104s]
Masking reference...  [32.117s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.117s]
Allocating buffers...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.398s]
Building query seed array...  [2.215s]
Computing hash join...  [5.211s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [79.608s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.462s]
Building query seed array...  [2.502s]
Computing hash join...  [5.208s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [52.114s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.597s]
Building query seed array...  [2.641s]
Computing hash join...  [5.213s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [43.42s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.47s]
Building query seed array...  [2.138s]
Computing hash join...  [5.084s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [39.968s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.087s]
Building query seed array...  [2.01s]
Computing hash join...  [4.963s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [39.236s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.424s]
Building query seed array...  [2.233s]
Computing hash join...  [4.916s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [31.68s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.227s]
Building query seed array...  [2.438s]
Computing hash join...  [5.066s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [37.15s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.043s]
Building query seed array...  [1.962s]
Computing hash join...  [5.014s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [30.38s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.135s]
Clearing query masking...  [1.592s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.222s]
Sorting trace points...  [1.243s]
Computing alignments...  [30.665s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.172s]
Computing alignments...  [30.635s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.158s]
Sorting trace points...  [0.88s]
Computing alignments...  [30.852s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.079s]
Sorting trace points...  [0.891s]
Computing alignments...  [30.877s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.145s]
Computing alignments...  [30.678s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.042s]
Sorting trace points...  [0.885s]
Computing alignments...  [31.004s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.049s]
Computing alignments...  [30.948s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.135s]
Computing alignments...  [30.303s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.061s]
Computing alignments...  [31.262s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.22s]
Computing alignments...  [31.731s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.082s]
Sorting trace points...  [0.898s]
Computing alignments...  [31.769s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.206s]
Sorting trace points...  [0.914s]
Computing alignments...  [31.929s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.085s]
Sorting trace points...  [1.22s]
Computing alignments...  [31.891s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.232s]
Computing alignments...  [32.007s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.204s]
Computing alignments...  [31.881s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [0.996s]
Computing alignments...  [32.038s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [525.992s]
Deallocating reference...  [0.074s]
Loading reference sequences...  [29.749s]
Masking reference...  [32.079s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.103s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.77s]
Building query seed array...  [2.265s]
Computing hash join...  [5.151s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [79.536s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.495s]
Building query seed array...  [2.425s]
Computing hash join...  [5.118s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [50.517s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.29s]
Building query seed array...  [2.754s]
Computing hash join...  [5.083s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [45.1s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.438s]
Building query seed array...  [2.111s]
Computing hash join...  [5.142s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [40.983s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.977s]
Building query seed array...  [2.001s]
Computing hash join...  [4.894s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [39.597s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.279s]
Building query seed array...  [2.262s]
Computing hash join...  [4.917s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [30.899s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.338s]
Building query seed array...  [2.389s]
Computing hash join...  [4.924s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [35.054s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.269s]
Building query seed array...  [1.909s]
Computing hash join...  [4.957s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [29.771s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.517s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.131s]
Sorting trace points...  [1.216s]
Computing alignments...  [30.681s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.131s]
Sorting trace points...  [1.164s]
Computing alignments...  [30.628s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.067s]
Sorting trace points...  [0.962s]
Computing alignments...  [30.609s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.099s]
Sorting trace points...  [1.098s]
Computing alignments...  [30.793s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.204s]
Computing alignments...  [30.653s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.197s]
Computing alignments...  [31.092s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.213s]
Computing alignments...  [30.856s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.072s]
Sorting trace points...  [0.916s]
Computing alignments...  [30.358s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.179s]
Computing alignments...  [31.307s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.224s]
Computing alignments...  [31.725s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.088s]
Sorting trace points...  [1.205s]
Computing alignments...  [31.827s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.264s]
Computing alignments...  [31.944s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.229s]
Computing alignments...  [31.883s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.231s]
Computing alignments...  [32.002s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.236s]
Computing alignments...  [31.777s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.165s]
Computing alignments...  [31.976s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
 [526.388s]
Deallocating reference...  [0.071s]
Loading reference sequences...  [29.927s]
Masking reference...  [30.874s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.304s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.264s]
Building query seed array...  [2.145s]
Computing hash join...  [5.084s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [80.389s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.166s]
Building query seed array...  [2.427s]
Computing hash join...  [5.177s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [48.318s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.88s]
Building query seed array...  [2.716s]
Computing hash join...  [5.12s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [43.153s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.436s]
Building query seed array...  [2.138s]
Computing hash join...  [5.139s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [37.857s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.894s]
Building query seed array...  [1.935s]
Computing hash join...  [4.946s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [39.373s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.764s]
Building query seed array...  [2.236s]
Computing hash join...  [4.959s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [31.003s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.821s]
Building query seed array...  [2.348s]
Computing hash join...  [4.985s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [35.023s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.639s]
Building query seed array...  [1.979s]
Computing hash join...  [4.931s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [30.422s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.131s]
Clearing query masking...  [1.598s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.173s]
Sorting trace points...  [1.169s]
Computing alignments...  [30.679s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.062s]
Sorting trace points...  [0.997s]
Computing alignments...  [30.679s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.148s]
Computing alignments...  [30.718s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.093s]
Computing alignments...  [30.892s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.16s]
Computing alignments...  [30.695s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.105s]
Sorting trace points...  [1.164s]
Computing alignments...  [31.115s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.172s]
Computing alignments...  [30.908s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.09s]
Sorting trace points...  [1.152s]
Computing alignments...  [30.299s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.103s]
Sorting trace points...  [1.19s]
Computing alignments...  [31.331s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.216s]
Computing alignments...  [31.677s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.014s]
Computing alignments...  [31.792s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.162s]
Computing alignments...  [31.872s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.716s]
Sorting trace points...  [1.271s]
Computing alignments...  [31.905s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.225s]
Computing alignments...  [32.014s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.23s]
Computing alignments...  [31.838s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.24s]
Computing alignments...  [32.032s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
 [527.19s]
Deallocating reference...  [0.074s]
Loading reference sequences...  [29.776s]
Masking reference...  [30.858s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.677s]
Allocating buffers...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.271s]
Building query seed array...  [2.163s]
Computing hash join...  [5.194s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [80.648s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.558s]
Building query seed array...  [2.528s]
Computing hash join...  [5.25s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [50.376s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.586s]
Building query seed array...  [2.581s]
Computing hash join...  [5.136s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [44.982s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.265s]
Building query seed array...  [2.14s]
Computing hash join...  [5.209s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [39.951s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.206s]
Building query seed array...  [1.999s]
Computing hash join...  [5.027s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [39.7s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.993s]
Building query seed array...  [2.253s]
Computing hash join...  [4.941s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [32.245s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.042s]
Building query seed array...  [2.397s]
Computing hash join...  [4.983s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [35.565s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.994s]
Building query seed array...  [1.93s]
Computing hash join...  [4.877s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [30.894s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.122s]
Clearing query masking...  [1.619s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.201s]
Sorting trace points...  [1.202s]
Computing alignments...  [30.534s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.152s]
Computing alignments...  [30.602s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.087s]
Sorting trace points...  [1.143s]
Computing alignments...  [30.68s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.085s]
Sorting trace points...  [0.88s]
Computing alignments...  [30.911s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.156s]
Computing alignments...  [30.649s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.272s]
Sorting trace points...  [1.208s]
Computing alignments...  [30.998s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.157s]
Computing alignments...  [30.862s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.073s]
Sorting trace points...  [0.959s]
Computing alignments...  [30.231s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.038s]
Sorting trace points...  [0.906s]
Computing alignments...  [31.209s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.141s]
Computing alignments...  [31.703s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.183s]
Computing alignments...  [31.864s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.029s]
Computing alignments...  [31.97s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.215s]
Computing alignments...  [31.947s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.259s]
Computing alignments...  [31.96s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.204s]
Computing alignments...  [31.875s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.19s]
Computing alignments...  [31.96s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
 [525.607s]
Deallocating reference...  [0.078s]
Loading reference sequences...  [29.722s]
Masking reference...  [30.851s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.14s]
Allocating buffers...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [9.967s]
Building query seed array...  [2.123s]
Computing hash join...  [5.195s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [79.161s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.52s]
Building query seed array...  [2.479s]
Computing hash join...  [5.208s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [48.919s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.715s]
Building query seed array...  [2.565s]
Computing hash join...  [5.075s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [43.272s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.077s]
Building query seed array...  [2.087s]
Computing hash join...  [5.06s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [38.899s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.011s]
Building query seed array...  [1.914s]
Computing hash join...  [4.907s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [38.791s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.246s]
Building query seed array...  [2.236s]
Computing hash join...  [4.882s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [31.268s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.453s]
Building query seed array...  [2.337s]
Computing hash join...  [4.952s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [34.521s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.023s]
Building query seed array...  [1.987s]
Computing hash join...  [4.992s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [29.525s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.132s]
Clearing query masking...  [1.646s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.226s]
Sorting trace points...  [1.244s]
Computing alignments...  [30.701s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.076s]
Sorting trace points...  [0.925s]
Computing alignments...  [30.544s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.125s]
Computing alignments...  [30.655s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.064s]
Sorting trace points...  [0.91s]
Computing alignments...  [31.086s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.17s]
Computing alignments...  [30.551s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.213s]
Computing alignments...  [30.912s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.184s]
Computing alignments...  [30.65s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.12s]
Computing alignments...  [30.175s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.071s]
Sorting trace points...  [0.888s]
Computing alignments...  [31.291s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.204s]
Computing alignments...  [31.615s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.197s]
Computing alignments...  [31.596s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.101s]
Sorting trace points...  [1.19s]
Computing alignments...  [31.731s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.184s]
Computing alignments...  [31.773s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.209s]
Computing alignments...  [31.862s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.189s]
Computing alignments...  [31.776s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.205s]
Computing alignments...  [32.004s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [524.548s]
Deallocating reference...  [0.076s]
Loading reference sequences...  [30.026s]
Masking reference...  [32.118s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.056s]
Allocating buffers...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.292s]
Building query seed array...  [2.145s]
Computing hash join...  [5.233s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [80.651s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.405s]
Building query seed array...  [2.434s]
Computing hash join...  [5.119s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [49.045s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [12.966s]
Building query seed array...  [2.567s]
Computing hash join...  [5.124s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [43.654s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.202s]
Building query seed array...  [2.097s]
Computing hash join...  [5.145s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [38.258s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.925s]
Building query seed array...  [1.947s]
Computing hash join...  [4.901s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [39.635s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.788s]
Building query seed array...  [2.247s]
Computing hash join...  [4.922s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [31.299s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.444s]
Building query seed array...  [2.444s]
Computing hash join...  [4.99s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [34.508s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.998s]
Building query seed array...  [1.978s]
Computing hash join...  [5s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [30.253s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.128s]
Clearing query masking...  [1.604s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.174s]
Sorting trace points...  [1.205s]
Computing alignments...  [30.629s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.181s]
Computing alignments...  [30.558s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.126s]
Computing alignments...  [30.762s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.159s]
Computing alignments...  [30.665s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.174s]
Computing alignments...  [30.505s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.001s]
Sorting trace points...  [0.919s]
Computing alignments...  [30.935s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.169s]
Computing alignments...  [30.827s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.136s]
Sorting trace points...  [1.137s]
Computing alignments...  [30.184s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.231s]
Computing alignments...  [31.234s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.044s]
Sorting trace points...  [0.902s]
Computing alignments...  [31.714s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.221s]
Computing alignments...  [31.77s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.184s]
Computing alignments...  [31.941s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.222s]
Computing alignments...  [31.919s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.094s]
Sorting trace points...  [1.242s]
Computing alignments...  [31.987s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.065s]
Sorting trace points...  [0.959s]
Computing alignments...  [31.85s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [0.928s]
Computing alignments...  [31.993s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [524.876s]
Deallocating reference...  [0.077s]
Loading reference sequences...  [29.756s]
Masking reference...  [32.016s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.032s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.412s]
Building query seed array...  [2.1s]
Computing hash join...  [5.139s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [81.401s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.883s]
Building query seed array...  [2.439s]
Computing hash join...  [5.075s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [49.824s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.586s]
Building query seed array...  [2.577s]
Computing hash join...  [5.146s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [42.845s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.964s]
Building query seed array...  [2.074s]
Computing hash join...  [5.022s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [38.302s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.268s]
Building query seed array...  [1.956s]
Computing hash join...  [4.949s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [39.621s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.077s]
Building query seed array...  [2.172s]
Computing hash join...  [4.911s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [31.482s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.064s]
Building query seed array...  [2.43s]
Computing hash join...  [4.908s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [35.75s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.767s]
Building query seed array...  [2.001s]
Computing hash join...  [4.952s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [30.802s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.621s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.164s]
Sorting trace points...  [1.232s]
Computing alignments...  [30.665s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.072s]
Computing alignments...  [30.462s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.111s]
Sorting trace points...  [0.895s]
Computing alignments...  [30.7s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.129s]
Computing alignments...  [31.069s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.04s]
Sorting trace points...  [1.044s]
Computing alignments...  [30.602s]
Deallocating buffers...  [0.02s]
Loading trace points...  [1.745s]
Sorting trace points...  [1.08s]
Computing alignments...  [31.056s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.204s]
Computing alignments...  [30.785s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.129s]
Sorting trace points...  [1.183s]
Computing alignments...  [30.214s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.207s]
Computing alignments...  [31.247s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.2s]
Computing alignments...  [31.607s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.059s]
Sorting trace points...  [0.949s]
Computing alignments...  [31.694s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.062s]
Sorting trace points...  [0.925s]
Computing alignments...  [31.77s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.179s]
Computing alignments...  [31.877s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.18s]
Computing alignments...  [31.918s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.241s]
Computing alignments...  [31.779s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.192s]
Computing alignments...  [31.973s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
 [526.491s]
Deallocating reference...  [0.074s]
Loading reference sequences...  [23.717s]
Masking reference...  [24.978s]
Initializing dictionary...  [0.064s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [26.276s]
Allocating buffers...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.612s]
Building query seed array...  [2.223s]
Computing hash join...  [4.288s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [64.771s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [10.404s]
Building query seed array...  [2.439s]
Computing hash join...  [4.275s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [41.634s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [11.122s]
Building query seed array...  [2.631s]
Computing hash join...  [4.288s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [35.911s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [8.191s]
Building query seed array...  [2.109s]
Computing hash join...  [4.236s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [31.29s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [8.227s]
Building query seed array...  [2.082s]
Computing hash join...  [4.173s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [32.138s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [9.957s]
Building query seed array...  [2.327s]
Computing hash join...  [4.177s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [25.298s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [10.782s]
Building query seed array...  [2.363s]
Computing hash join...  [4.125s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [28.396s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [7.963s]
Building query seed array...  [1.85s]
Computing hash join...  [4.15s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [25.265s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.106s]
Clearing query masking...  [1.511s]
Opening temporary output file...  [0.018s]
Computing alignments... Loading trace points...  [10.62s]
Sorting trace points...  [1.994s]
Computing alignments...  [48.738s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.155s]
Sorting trace points...  [1.82s]
Computing alignments...  [48.843s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.138s]
Sorting trace points...  [1.575s]
Computing alignments...  [49.01s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0.164s]
Sorting trace points...  [1.924s]
Computing alignments...  [48.661s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.139s]
Sorting trace points...  [1.747s]
Computing alignments...  [50.129s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.155s]
Sorting trace points...  [2.004s]
Computing alignments...  [50.74s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.161s]
Sorting trace points...  [1.616s]
Computing alignments...  [50.884s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0s]
Sorting trace points...  [1.66s]
Computing alignments...  [50.663s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0s]
 [423.847s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [0.077s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [1873.49s]
 [1873.49s]
Deallocating queries...  [0.066s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [4.371s]
 [5.759s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 17503.1s
Reported 2316928186 pairwise alignments, 2316928186 HSPs.
13656214 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C27_R1.fastp-trim.20230215.fq.gz complete: C27_R1.blastx.meganized.daa

Now MEGANizing C27_R1.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: C27_R1.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 80% 100% (274.0s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.5s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (4,321.5s)
Total reads:       13,656,214
With hits:          13,656,214 
Alignments:      2,309,745,272
Assig. Taxonomy:    12,653,262
Assig. SEED:           138,833
Assig. EGGNOG:          91,355
Assig. GTDB:           482,937
Assig. EC:           2,089,450
Assig. INTERPRO2GO:  1,157,989
MinSupport set to: 6828
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.3s)
Min-supp. changes:       5,321
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (15.1s)
Min-supp. changes:       4,449
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (43.7s)
Binning reads Syncing
100% (0.4s)
Class. Taxonomy:            85
Class. SEED:               558
Class. EGGNOG:           1,970
Class. GTDB:                27
Class. EC:               2,598
Class. INTERPRO2GO:      8,007
Total time:  4,665s
Peak memory: 29.2 of 195.3G
MEGANization of C27_R1.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C27_R2.fastp-trim.20230215.fq.gz...
41fbf4bdc24085447a6be8879ddb0c05  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C27_R2.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C27_R2.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.334s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.948s]
Opening the output file...  [0s]
Loading query sequences...  [76.392s]
Masking queries...  [19.3s]
Algorithm: Double-indexed
Building query histograms...  [18.218s]
Loading reference sequences...  [29.803s]
Masking reference...  [32.041s]
Initializing dictionary...  [0.081s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.492s]
Allocating buffers...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.568s]
Building query seed array...  [2.174s]
Computing hash join...  [5.45s]
Masking low complexity seeds...  [0.283s]
Searching alignments...  [78.778s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.483s]
Building query seed array...  [2.451s]
Computing hash join...  [5.392s]
Masking low complexity seeds...  [0.287s]
Searching alignments...  [51.373s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.502s]
Building query seed array...  [2.555s]
Computing hash join...  [5.222s]
Masking low complexity seeds...  [0.281s]
Searching alignments...  [43.674s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.124s]
Building query seed array...  [2.179s]
Computing hash join...  [5.282s]
Masking low complexity seeds...  [0.278s]
Searching alignments...  [38.729s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.042s]
Building query seed array...  [1.879s]
Computing hash join...  [5.079s]
Masking low complexity seeds...  [0.267s]
Searching alignments...  [42.719s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.404s]
Building query seed array...  [2.239s]
Computing hash join...  [5.054s]
Masking low complexity seeds...  [0.269s]
Searching alignments...  [31.169s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.708s]
Building query seed array...  [2.37s]
Computing hash join...  [5.112s]
Masking low complexity seeds...  [0.276s]
Searching alignments...  [36.206s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.084s]
Building query seed array...  [1.956s]
Computing hash join...  [5.061s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [31.887s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.136s]
Clearing query masking...  [1.647s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.187s]
Sorting trace points...  [1.224s]
Computing alignments...  [30.767s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.11s]
Sorting trace points...  [0.98s]
Computing alignments...  [30.42s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.044s]
Sorting trace points...  [0.979s]
Computing alignments...  [30.256s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.158s]
Computing alignments...  [30.38s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.108s]
Sorting trace points...  [1.142s]
Computing alignments...  [30.21s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.122s]
Sorting trace points...  [1.142s]
Computing alignments...  [30.083s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.091s]
Sorting trace points...  [1.154s]
Computing alignments...  [29.914s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.069s]
Computing alignments...  [29.928s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.038s]
Sorting trace points...  [1.207s]
Computing alignments...  [31.804s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.232s]
Computing alignments...  [32.424s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.083s]
Computing alignments...  [32.549s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.108s]
Computing alignments...  [32.62s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.258s]
Computing alignments...  [32.531s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.216s]
Computing alignments...  [32.65s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.042s]
Computing alignments...  [32.475s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.242s]
Computing alignments...  [32.773s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [527.581s]
Deallocating reference...  [0.078s]
Loading reference sequences...  [36.177s]
Masking reference...  [30.927s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.923s]
Allocating buffers...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.365s]
Building query seed array...  [2.181s]
Computing hash join...  [5.296s]
Masking low complexity seeds...  [0.296s]
Searching alignments...  [77.283s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.56s]
Building query seed array...  [2.541s]
Computing hash join...  [5.303s]
Masking low complexity seeds...  [0.279s]
Searching alignments...  [48.47s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.948s]
Building query seed array...  [2.679s]
Computing hash join...  [5.23s]
Masking low complexity seeds...  [0.284s]
Searching alignments...  [43.194s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.79s]
Building query seed array...  [2.106s]
Computing hash join...  [5.3s]
Masking low complexity seeds...  [0.285s]
Searching alignments...  [38.504s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.18s]
Building query seed array...  [1.9s]
Computing hash join...  [5.086s]
Masking low complexity seeds...  [0.273s]
Searching alignments...  [42.92s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.048s]
Building query seed array...  [2.265s]
Computing hash join...  [5.256s]
Masking low complexity seeds...  [0.273s]
Searching alignments...  [30.918s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.212s]
Building query seed array...  [2.447s]
Computing hash join...  [5.086s]
Masking low complexity seeds...  [0.268s]
Searching alignments...  [35.129s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.013s]
Building query seed array...  [1.914s]
Computing hash join...  [5.118s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [30.101s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.141s]
Clearing query masking...  [1.67s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.064s]
Sorting trace points...  [1.193s]
Computing alignments...  [31.008s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.163s]
Computing alignments...  [30.45s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.078s]
Computing alignments...  [30.276s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.127s]
Computing alignments...  [30.112s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.072s]
Sorting trace points...  [0.977s]
Computing alignments...  [30.219s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.127s]
Computing alignments...  [29.972s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.126s]
Computing alignments...  [29.762s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.114s]
Computing alignments...  [30.046s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.15s]
Computing alignments...  [31.645s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.224s]
Computing alignments...  [32.244s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.093s]
Sorting trace points...  [1.254s]
Computing alignments...  [32.31s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.236s]
Computing alignments...  [32.598s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.166s]
Computing alignments...  [32.367s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.073s]
Computing alignments...  [32.473s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.227s]
Computing alignments...  [32.233s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.18s]
Computing alignments...  [32.6s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
 [526.034s]
Deallocating reference...  [0.071s]
Loading reference sequences...  [29.744s]
Masking reference...  [31.388s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.726s]
Allocating buffers...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.401s]
Building query seed array...  [2.181s]
Computing hash join...  [5.339s]
Masking low complexity seeds...  [0.287s]
Searching alignments...  [78.712s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.284s]
Building query seed array...  [2.468s]
Computing hash join...  [5.203s]
Masking low complexity seeds...  [0.272s]
Searching alignments...  [50.824s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.384s]
Building query seed array...  [2.652s]
Computing hash join...  [5.324s]
Masking low complexity seeds...  [0.292s]
Searching alignments...  [44.132s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.763s]
Building query seed array...  [2.094s]
Computing hash join...  [5.432s]
Masking low complexity seeds...  [0.287s]
Searching alignments...  [39.883s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.771s]
Building query seed array...  [1.891s]
Computing hash join...  [5.086s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [45.374s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.498s]
Building query seed array...  [2.195s]
Computing hash join...  [5.08s]
Masking low complexity seeds...  [0.267s]
Searching alignments...  [32.54s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.179s]
Building query seed array...  [2.328s]
Computing hash join...  [5.195s]
Masking low complexity seeds...  [0.276s]
Searching alignments...  [37.712s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.269s]
Building query seed array...  [1.905s]
Computing hash join...  [5.044s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [30.999s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.13s]
Clearing query masking...  [1.606s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.15s]
Sorting trace points...  [1.192s]
Computing alignments...  [30.979s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.005s]
Computing alignments...  [30.42s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.125s]
Computing alignments...  [30.189s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.128s]
Computing alignments...  [30.338s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.095s]
Sorting trace points...  [1.15s]
Computing alignments...  [30.32s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.129s]
Computing alignments...  [30.098s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.135s]
Sorting trace points...  [0.901s]
Computing alignments...  [29.982s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.12s]
Computing alignments...  [30.133s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.176s]
Computing alignments...  [31.805s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.22s]
Computing alignments...  [32.416s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.196s]
Computing alignments...  [32.308s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.141s]
Sorting trace points...  [1.244s]
Computing alignments...  [32.569s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.085s]
Sorting trace points...  [1.217s]
Computing alignments...  [32.416s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.044s]
Sorting trace points...  [0.906s]
Computing alignments...  [32.573s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.249s]
Computing alignments...  [32.334s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [0.946s]
Computing alignments...  [32.664s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
 [526.992s]
Deallocating reference...  [0.074s]
Loading reference sequences...  [29.75s]
Masking reference...  [31.962s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [31.96s]
Allocating buffers...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.333s]
Building query seed array...  [2.207s]
Computing hash join...  [5.304s]
Masking low complexity seeds...  [0.279s]
Searching alignments...  [78.572s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.355s]
Building query seed array...  [2.507s]
Computing hash join...  [5.274s]
Masking low complexity seeds...  [0.285s]
Searching alignments...  [50.29s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.648s]
Building query seed array...  [2.619s]
Computing hash join...  [5.252s]
Masking low complexity seeds...  [0.283s]
Searching alignments...  [44.956s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.27s]
Building query seed array...  [2.104s]
Computing hash join...  [5.391s]
Masking low complexity seeds...  [0.292s]
Searching alignments...  [39.352s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.838s]
Building query seed array...  [1.987s]
Computing hash join...  [4.992s]
Masking low complexity seeds...  [0.281s]
Searching alignments...  [43.003s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.884s]
Building query seed array...  [2.242s]
Computing hash join...  [5.144s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [31.163s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.574s]
Building query seed array...  [2.383s]
Computing hash join...  [5.15s]
Masking low complexity seeds...  [0.274s]
Searching alignments...  [35.629s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.916s]
Building query seed array...  [1.961s]
Computing hash join...  [5.044s]
Masking low complexity seeds...  [0.267s]
Searching alignments...  [29.328s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.13s]
Clearing query masking...  [1.644s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.164s]
Sorting trace points...  [1.2s]
Computing alignments...  [30.479s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.108s]
Computing alignments...  [30.21s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.148s]
Computing alignments...  [30.131s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.146s]
Computing alignments...  [30.194s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.06s]
Sorting trace points...  [0.939s]
Computing alignments...  [30.118s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.11s]
Sorting trace points...  [1.119s]
Computing alignments...  [30.022s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.099s]
Computing alignments...  [29.849s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.165s]
Computing alignments...  [30.019s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.182s]
Computing alignments...  [31.716s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.225s]
Computing alignments...  [32.484s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.226s]
Computing alignments...  [32.422s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.259s]
Computing alignments...  [32.603s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.099s]
Computing alignments...  [32.547s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.221s]
Computing alignments...  [32.676s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.218s]
Computing alignments...  [32.359s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.235s]
Computing alignments...  [32.718s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0s]
 [526.628s]
Deallocating reference...  [0.08s]
Loading reference sequences...  [30.502s]
Masking reference...  [32.043s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [31.961s]
Allocating buffers...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.219s]
Building query seed array...  [2.231s]
Computing hash join...  [5.316s]
Masking low complexity seeds...  [0.282s]
Searching alignments...  [77.164s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.64s]
Building query seed array...  [2.498s]
Computing hash join...  [5.219s]
Masking low complexity seeds...  [0.293s]
Searching alignments...  [48.464s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.038s]
Building query seed array...  [2.666s]
Computing hash join...  [5.327s]
Masking low complexity seeds...  [0.29s]
Searching alignments...  [44.524s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.043s]
Building query seed array...  [2.124s]
Computing hash join...  [5.187s]
Masking low complexity seeds...  [0.28s]
Searching alignments...  [38.969s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.988s]
Building query seed array...  [1.982s]
Computing hash join...  [5.05s]
Masking low complexity seeds...  [0.266s]
Searching alignments...  [41.994s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.731s]
Building query seed array...  [2.29s]
Computing hash join...  [4.956s]
Masking low complexity seeds...  [0.266s]
Searching alignments...  [31.228s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.075s]
Building query seed array...  [2.358s]
Computing hash join...  [5.005s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [35.316s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.173s]
Building query seed array...  [1.921s]
Computing hash join...  [4.997s]
Masking low complexity seeds...  [0.272s]
Searching alignments...  [29.627s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.127s]
Clearing query masking...  [1.575s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.341s]
Sorting trace points...  [0.974s]
Computing alignments...  [30.484s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.142s]
Computing alignments...  [30.284s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.14s]
Computing alignments...  [30.074s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.125s]
Computing alignments...  [30.131s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.112s]
Computing alignments...  [30.004s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.129s]
Computing alignments...  [29.837s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.125s]
Sorting trace points...  [1.131s]
Computing alignments...  [29.723s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.143s]
Sorting trace points...  [1.127s]
Computing alignments...  [29.871s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.11s]
Computing alignments...  [31.593s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.039s]
Sorting trace points...  [1.226s]
Computing alignments...  [32.25s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.236s]
Computing alignments...  [32.214s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.256s]
Computing alignments...  [32.282s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.087s]
Computing alignments...  [32.279s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.207s]
Computing alignments...  [32.473s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.199s]
Computing alignments...  [32.235s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.009s]
Computing alignments...  [32.714s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
 [524.197s]
Deallocating reference...  [0.075s]
Loading reference sequences...  [31.816s]
Masking reference...  [32.11s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.214s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.436s]
Building query seed array...  [2.172s]
Computing hash join...  [5.265s]
Masking low complexity seeds...  [0.282s]
Searching alignments...  [75.697s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.288s]
Building query seed array...  [2.465s]
Computing hash join...  [5.343s]
Masking low complexity seeds...  [0.29s]
Searching alignments...  [47.423s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.478s]
Building query seed array...  [2.658s]
Computing hash join...  [5.295s]
Masking low complexity seeds...  [0.277s]
Searching alignments...  [41.879s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.179s]
Building query seed array...  [2.231s]
Computing hash join...  [5.146s]
Masking low complexity seeds...  [0.278s]
Searching alignments...  [37.408s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.962s]
Building query seed array...  [1.978s]
Computing hash join...  [5.066s]
Masking low complexity seeds...  [0.276s]
Searching alignments...  [40.273s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.089s]
Building query seed array...  [2.224s]
Computing hash join...  [5.048s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [31.458s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.057s]
Building query seed array...  [2.388s]
Computing hash join...  [5.011s]
Masking low complexity seeds...  [0.276s]
Searching alignments...  [33.871s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.207s]
Building query seed array...  [1.975s]
Computing hash join...  [5.063s]
Masking low complexity seeds...  [0.273s]
Searching alignments...  [31s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.139s]
Clearing query masking...  [1.587s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.378s]
Sorting trace points...  [1.091s]
Computing alignments...  [29.908s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.088s]
Sorting trace points...  [1.094s]
Computing alignments...  [29.901s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.152s]
Computing alignments...  [29.737s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.104s]
Sorting trace points...  [1.155s]
Computing alignments...  [29.849s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.064s]
Sorting trace points...  [0.952s]
Computing alignments...  [29.777s]
Deallocating buffers...  [0.022s]
Loading trace points...  [1.076s]
Sorting trace points...  [1.123s]
Computing alignments...  [29.477s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.145s]
Computing alignments...  [29.439s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.161s]
Sorting trace points...  [1.123s]
Computing alignments...  [29.536s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.201s]
Computing alignments...  [31.361s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.093s]
Sorting trace points...  [1.241s]
Computing alignments...  [32.045s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.059s]
Sorting trace points...  [0.977s]
Computing alignments...  [32.031s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.221s]
Computing alignments...  [32.1s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.04s]
Sorting trace points...  [1.305s]
Computing alignments...  [32.05s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.089s]
Sorting trace points...  [1.187s]
Computing alignments...  [32.253s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.105s]
Sorting trace points...  [1.237s]
Computing alignments...  [32.072s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.19s]
Computing alignments...  [32.318s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
 [521.159s]
Deallocating reference...  [0.072s]
Loading reference sequences...  [30.099s]
Masking reference...  [30.948s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.15s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.077s]
Building query seed array...  [2.104s]
Computing hash join...  [5.288s]
Masking low complexity seeds...  [0.279s]
Searching alignments...  [78.857s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.253s]
Building query seed array...  [2.473s]
Computing hash join...  [5.319s]
Masking low complexity seeds...  [0.28s]
Searching alignments...  [50.185s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.12s]
Building query seed array...  [2.67s]
Computing hash join...  [5.276s]
Masking low complexity seeds...  [0.292s]
Searching alignments...  [44.464s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.194s]
Building query seed array...  [2.084s]
Computing hash join...  [5.315s]
Masking low complexity seeds...  [0.284s]
Searching alignments...  [39.875s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.217s]
Building query seed array...  [1.986s]
Computing hash join...  [5.016s]
Masking low complexity seeds...  [0.272s]
Searching alignments...  [44.711s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.297s]
Building query seed array...  [2.312s]
Computing hash join...  [5.023s]
Masking low complexity seeds...  [0.267s]
Searching alignments...  [32.646s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.347s]
Building query seed array...  [2.365s]
Computing hash join...  [5.07s]
Masking low complexity seeds...  [0.269s]
Searching alignments...  [36.484s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.769s]
Building query seed array...  [1.917s]
Computing hash join...  [5.032s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [30.764s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.138s]
Clearing query masking...  [1.596s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.126s]
Sorting trace points...  [1.198s]
Computing alignments...  [30.464s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.022s]
Computing alignments...  [30.313s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.165s]
Computing alignments...  [30.259s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.119s]
Computing alignments...  [30.264s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.117s]
Computing alignments...  [30.262s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.154s]
Computing alignments...  [29.828s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.133s]
Computing alignments...  [29.818s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.124s]
Computing alignments...  [29.955s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.211s]
Computing alignments...  [31.641s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.191s]
Computing alignments...  [32.272s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.257s]
Computing alignments...  [32.317s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.247s]
Computing alignments...  [32.404s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.086s]
Computing alignments...  [32.428s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.219s]
Computing alignments...  [32.569s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.153s]
Computing alignments...  [32.222s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.247s]
Computing alignments...  [32.656s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
 [525.697s]
Deallocating reference...  [0.072s]
Loading reference sequences...  [29.635s]
Masking reference...  [30.828s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.296s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.232s]
Building query seed array...  [2.211s]
Computing hash join...  [5.251s]
Masking low complexity seeds...  [0.272s]
Searching alignments...  [79.183s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.111s]
Building query seed array...  [2.494s]
Computing hash join...  [5.27s]
Masking low complexity seeds...  [0.273s]
Searching alignments...  [50.172s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.713s]
Building query seed array...  [2.662s]
Computing hash join...  [5.213s]
Masking low complexity seeds...  [0.285s]
Searching alignments...  [44.788s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.954s]
Building query seed array...  [2.148s]
Computing hash join...  [5.197s]
Masking low complexity seeds...  [0.279s]
Searching alignments...  [39.475s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.04s]
Building query seed array...  [1.948s]
Computing hash join...  [5.074s]
Masking low complexity seeds...  [0.27s]
Searching alignments...  [41.038s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.546s]
Building query seed array...  [2.25s]
Computing hash join...  [5.05s]
Masking low complexity seeds...  [0.271s]
Searching alignments...  [31.617s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.39s]
Building query seed array...  [2.419s]
Computing hash join...  [5.044s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [34.325s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.14s]
Building query seed array...  [1.959s]
Computing hash join...  [5.026s]
Masking low complexity seeds...  [0.265s]
Searching alignments...  [29.456s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.542s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.124s]
Sorting trace points...  [1.218s]
Computing alignments...  [30.342s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.144s]
Computing alignments...  [30.151s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.064s]
Sorting trace points...  [0.951s]
Computing alignments...  [30.081s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.046s]
Sorting trace points...  [0.894s]
Computing alignments...  [30.14s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.089s]
Computing alignments...  [30.184s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.135s]
Computing alignments...  [29.773s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.098s]
Computing alignments...  [29.888s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.128s]
Computing alignments...  [29.874s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.222s]
Computing alignments...  [31.714s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.23s]
Computing alignments...  [32.405s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.246s]
Computing alignments...  [32.342s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.095s]
Sorting trace points...  [1.252s]
Computing alignments...  [32.445s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.233s]
Computing alignments...  [32.479s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.053s]
Sorting trace points...  [0.967s]
Computing alignments...  [32.493s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.195s]
Computing alignments...  [32.244s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.224s]
Computing alignments...  [32.627s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [524.751s]
Deallocating reference...  [0.079s]
Loading reference sequences...  [29.758s]
Masking reference...  [30.837s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.748s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.289s]
Building query seed array...  [2.145s]
Computing hash join...  [5.277s]
Masking low complexity seeds...  [0.289s]
Searching alignments...  [78.358s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.8s]
Building query seed array...  [2.465s]
Computing hash join...  [5.355s]
Masking low complexity seeds...  [0.285s]
Searching alignments...  [47.471s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.429s]
Building query seed array...  [2.636s]
Computing hash join...  [5.186s]
Masking low complexity seeds...  [0.287s]
Searching alignments...  [43.505s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.118s]
Building query seed array...  [2.11s]
Computing hash join...  [5.219s]
Masking low complexity seeds...  [0.286s]
Searching alignments...  [38.293s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.2s]
Building query seed array...  [1.93s]
Computing hash join...  [5.067s]
Masking low complexity seeds...  [0.28s]
Searching alignments...  [42.727s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.722s]
Building query seed array...  [2.268s]
Computing hash join...  [4.988s]
Masking low complexity seeds...  [0.27s]
Searching alignments...  [31.233s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.455s]
Building query seed array...  [2.43s]
Computing hash join...  [5.049s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [34.646s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.172s]
Building query seed array...  [1.906s]
Computing hash join...  [5.066s]
Masking low complexity seeds...  [0.282s]
Searching alignments...  [30.687s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.13s]
Clearing query masking...  [1.595s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.168s]
Sorting trace points...  [1.195s]
Computing alignments...  [30.452s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.147s]
Computing alignments...  [30.171s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.141s]
Sorting trace points...  [0.95s]
Computing alignments...  [30.005s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.117s]
Computing alignments...  [30.034s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.147s]
Computing alignments...  [29.922s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.136s]
Computing alignments...  [29.794s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.158s]
Computing alignments...  [29.712s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.044s]
Sorting trace points...  [0.974s]
Computing alignments...  [29.771s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.2s]
Computing alignments...  [31.606s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.226s]
Computing alignments...  [32.191s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.098s]
Sorting trace points...  [1.208s]
Computing alignments...  [32.218s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.202s]
Computing alignments...  [32.319s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.194s]
Sorting trace points...  [1.258s]
Computing alignments...  [32.309s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.199s]
Computing alignments...  [32.483s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.083s]
Sorting trace points...  [0.951s]
Computing alignments...  [32.165s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.107s]
Computing alignments...  [32.51s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [523.385s]
Deallocating reference...  [0.073s]
Loading reference sequences...  [29.775s]
Masking reference...  [32.108s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [31.852s]
Allocating buffers...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [9.999s]
Building query seed array...  [2.202s]
Computing hash join...  [5.379s]
Masking low complexity seeds...  [0.29s]
Searching alignments...  [78.674s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.032s]
Building query seed array...  [2.491s]
Computing hash join...  [5.203s]
Masking low complexity seeds...  [0.29s]
Searching alignments...  [50.594s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.361s]
Building query seed array...  [2.589s]
Computing hash join...  [5.252s]
Masking low complexity seeds...  [0.28s]
Searching alignments...  [44.591s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.998s]
Building query seed array...  [2.228s]
Computing hash join...  [5.285s]
Masking low complexity seeds...  [0.28s]
Searching alignments...  [38.2s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.862s]
Building query seed array...  [1.932s]
Computing hash join...  [4.948s]
Masking low complexity seeds...  [0.271s]
Searching alignments...  [43.606s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.952s]
Building query seed array...  [2.243s]
Computing hash join...  [4.939s]
Masking low complexity seeds...  [0.27s]
Searching alignments...  [31.275s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.819s]
Building query seed array...  [2.389s]
Computing hash join...  [4.947s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [37.216s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.976s]
Building query seed array...  [1.957s]
Computing hash join...  [4.997s]
Masking low complexity seeds...  [0.273s]
Searching alignments...  [30.153s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.13s]
Clearing query masking...  [1.596s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.174s]
Sorting trace points...  [1.204s]
Computing alignments...  [30.298s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [0.868s]
Computing alignments...  [30.206s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.053s]
Computing alignments...  [30.013s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.275s]
Computing alignments...  [30.19s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.077s]
Sorting trace points...  [0.958s]
Computing alignments...  [29.972s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.112s]
Computing alignments...  [29.815s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.115s]
Sorting trace points...  [1.151s]
Computing alignments...  [29.77s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.124s]
Computing alignments...  [29.767s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.116s]
Computing alignments...  [31.56s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.092s]
Sorting trace points...  [1.24s]
Computing alignments...  [32.271s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.187s]
Computing alignments...  [32.247s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.24s]
Computing alignments...  [32.344s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.224s]
Computing alignments...  [32.408s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.05s]
Sorting trace points...  [0.961s]
Computing alignments...  [32.488s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.239s]
Computing alignments...  [32.258s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.208s]
Computing alignments...  [32.52s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
 [523.673s]
Deallocating reference...  [0.072s]
Loading reference sequences...  [29.748s]
Masking reference...  [30.867s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.475s]
Allocating buffers...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.268s]
Building query seed array...  [2.142s]
Computing hash join...  [5.281s]
Masking low complexity seeds...  [0.285s]
Searching alignments...  [77.16s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.678s]
Building query seed array...  [2.546s]
Computing hash join...  [5.33s]
Masking low complexity seeds...  [0.286s]
Searching alignments...  [48.926s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.491s]
Building query seed array...  [2.663s]
Computing hash join...  [5.176s]
Masking low complexity seeds...  [0.28s]
Searching alignments...  [44.258s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.951s]
Building query seed array...  [2.046s]
Computing hash join...  [5.265s]
Masking low complexity seeds...  [0.285s]
Searching alignments...  [39.417s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.059s]
Building query seed array...  [1.96s]
Computing hash join...  [5.028s]
Masking low complexity seeds...  [0.27s]
Searching alignments...  [41.987s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.183s]
Building query seed array...  [2.301s]
Computing hash join...  [4.99s]
Masking low complexity seeds...  [0.269s]
Searching alignments...  [31.205s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.771s]
Building query seed array...  [2.422s]
Computing hash join...  [5.005s]
Masking low complexity seeds...  [0.268s]
Searching alignments...  [35.296s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.756s]
Building query seed array...  [1.997s]
Computing hash join...  [5.061s]
Masking low complexity seeds...  [0.27s]
Searching alignments...  [30.041s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.136s]
Clearing query masking...  [1.667s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.083s]
Sorting trace points...  [1.215s]
Computing alignments...  [30.781s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.088s]
Sorting trace points...  [1.156s]
Computing alignments...  [30.129s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.002s]
Sorting trace points...  [1.13s]
Computing alignments...  [30.064s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.096s]
Computing alignments...  [30.029s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.126s]
Sorting trace points...  [0.864s]
Computing alignments...  [29.989s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.115s]
Computing alignments...  [29.597s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.077s]
Sorting trace points...  [0.864s]
Computing alignments...  [29.656s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.122s]
Computing alignments...  [29.82s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.199s]
Computing alignments...  [31.437s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.001s]
Sorting trace points...  [0.983s]
Computing alignments...  [32.291s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.246s]
Computing alignments...  [32.13s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.078s]
Sorting trace points...  [0.941s]
Computing alignments...  [32.32s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.044s]
Computing alignments...  [32.477s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.159s]
Computing alignments...  [32.389s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.207s]
Computing alignments...  [32.133s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [0.925s]
Computing alignments...  [32.484s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [522.184s]
Deallocating reference...  [0.076s]
Loading reference sequences...  [29.978s]
Masking reference...  [30.842s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.824s]
Allocating buffers...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.213s]
Building query seed array...  [2.143s]
Computing hash join...  [5.276s]
Masking low complexity seeds...  [0.283s]
Searching alignments...  [80.059s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.843s]
Building query seed array...  [2.438s]
Computing hash join...  [5.306s]
Masking low complexity seeds...  [0.279s]
Searching alignments...  [50.227s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.201s]
Building query seed array...  [2.68s]
Computing hash join...  [5.184s]
Masking low complexity seeds...  [0.278s]
Searching alignments...  [44.845s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.26s]
Building query seed array...  [2.076s]
Computing hash join...  [5.24s]
Masking low complexity seeds...  [0.288s]
Searching alignments...  [39.296s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.507s]
Building query seed array...  [1.915s]
Computing hash join...  [5.12s]
Masking low complexity seeds...  [0.274s]
Searching alignments...  [44.393s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.74s]
Building query seed array...  [2.263s]
Computing hash join...  [5.121s]
Masking low complexity seeds...  [0.275s]
Searching alignments...  [31.353s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.529s]
Building query seed array...  [2.346s]
Computing hash join...  [5.013s]
Masking low complexity seeds...  [0.268s]
Searching alignments...  [35.526s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.752s]
Building query seed array...  [1.951s]
Computing hash join...  [4.971s]
Masking low complexity seeds...  [0.256s]
Searching alignments...  [30.048s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.136s]
Clearing query masking...  [1.601s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.152s]
Sorting trace points...  [1.236s]
Computing alignments...  [30.191s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.147s]
Computing alignments...  [30.029s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.063s]
Sorting trace points...  [0.857s]
Computing alignments...  [29.998s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.165s]
Computing alignments...  [30.062s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.054s]
Sorting trace points...  [0.99s]
Computing alignments...  [29.93s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.101s]
Computing alignments...  [29.86s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.136s]
Computing alignments...  [29.781s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.077s]
Sorting trace points...  [0.887s]
Computing alignments...  [29.817s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.194s]
Computing alignments...  [31.697s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.231s]
Computing alignments...  [32.283s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.234s]
Computing alignments...  [32.318s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.223s]
Computing alignments...  [32.385s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.22s]
Computing alignments...  [32.381s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.239s]
Computing alignments...  [32.51s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.203s]
Computing alignments...  [32.19s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.22s]
Computing alignments...  [32.56s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
 [523.614s]
Deallocating reference...  [0.073s]
Loading reference sequences...  [30.626s]
Masking reference...  [32.071s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.311s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.209s]
Building query seed array...  [2.153s]
Computing hash join...  [5.245s]
Masking low complexity seeds...  [0.282s]
Searching alignments...  [79.193s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.626s]
Building query seed array...  [2.459s]
Computing hash join...  [5.341s]
Masking low complexity seeds...  [0.287s]
Searching alignments...  [48.43s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.395s]
Building query seed array...  [2.644s]
Computing hash join...  [5.242s]
Masking low complexity seeds...  [0.289s]
Searching alignments...  [44.289s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.286s]
Building query seed array...  [2.091s]
Computing hash join...  [5.282s]
Masking low complexity seeds...  [0.285s]
Searching alignments...  [38.232s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.162s]
Building query seed array...  [1.925s]
Computing hash join...  [4.982s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [43.351s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.967s]
Building query seed array...  [2.257s]
Computing hash join...  [4.987s]
Masking low complexity seeds...  [0.269s]
Searching alignments...  [31.544s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.141s]
Building query seed array...  [2.287s]
Computing hash join...  [5.016s]
Masking low complexity seeds...  [0.27s]
Searching alignments...  [36.05s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.86s]
Building query seed array...  [1.994s]
Computing hash join...  [5.065s]
Masking low complexity seeds...  [0.267s]
Searching alignments...  [30.487s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.136s]
Clearing query masking...  [1.545s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.072s]
Sorting trace points...  [1.178s]
Computing alignments...  [30.733s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [1.142s]
Computing alignments...  [30.305s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.108s]
Computing alignments...  [30.161s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.119s]
Computing alignments...  [30.178s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.103s]
Sorting trace points...  [1.131s]
Computing alignments...  [30.043s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.146s]
Computing alignments...  [29.84s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.137s]
Computing alignments...  [29.727s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.053s]
Sorting trace points...  [0.968s]
Computing alignments...  [29.842s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.033s]
Computing alignments...  [31.553s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.2s]
Computing alignments...  [32.136s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.099s]
Computing alignments...  [32.19s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.051s]
Sorting trace points...  [0.936s]
Computing alignments...  [32.321s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.275s]
Sorting trace points...  [1.257s]
Computing alignments...  [32.241s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.209s]
Computing alignments...  [32.434s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.068s]
Sorting trace points...  [0.926s]
Computing alignments...  [32.066s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.106s]
Computing alignments...  [32.497s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [523.384s]
Deallocating reference...  [0.074s]
Loading reference sequences...  [24.003s]
Masking reference...  [26.032s]
Initializing dictionary...  [0.063s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [25.927s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.235s]
Building query seed array...  [2.212s]
Computing hash join...  [4.37s]
Masking low complexity seeds...  [0.275s]
Searching alignments...  [63.091s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [10.244s]
Building query seed array...  [2.453s]
Computing hash join...  [4.451s]
Masking low complexity seeds...  [0.285s]
Searching alignments...  [38.307s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [10.831s]
Building query seed array...  [2.602s]
Computing hash join...  [4.334s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [35.126s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [8.007s]
Building query seed array...  [2.113s]
Computing hash join...  [4.396s]
Masking low complexity seeds...  [0.269s]
Searching alignments...  [32.893s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [8.053s]
Building query seed array...  [2.008s]
Computing hash join...  [4.234s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [34.936s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [9.962s]
Building query seed array...  [2.278s]
Computing hash join...  [4.204s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [25.962s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [10.573s]
Building query seed array...  [2.341s]
Computing hash join...  [4.264s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [29.035s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [8.394s]
Building query seed array...  [1.907s]
Computing hash join...  [4.2s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [24.413s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.104s]
Clearing query masking...  [1.57s]
Opening temporary output file...  [0.026s]
Computing alignments... Loading trace points...  [10.431s]
Sorting trace points...  [1.925s]
Computing alignments...  [48.037s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.135s]
Sorting trace points...  [1.82s]
Computing alignments...  [47.979s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.128s]
Sorting trace points...  [1.915s]
Computing alignments...  [47.45s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.115s]
Sorting trace points...  [1.886s]
Computing alignments...  [47.486s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.127s]
Sorting trace points...  [1.657s]
Computing alignments...  [50.802s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.13s]
Sorting trace points...  [1.482s]
Computing alignments...  [51.397s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.117s]
Sorting trace points...  [1.79s]
Computing alignments...  [51.509s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0s]
Sorting trace points...  [2s]
Computing alignments...  [51.277s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0s]
 [422.003s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [0.077s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [1827.87s]
 [1827.87s]
Deallocating queries...  [0.059s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [4.262s]
 [6.215s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 17494.9s
Reported 2230108757 pairwise alignments, 2230108757 HSPs.
13993965 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C27_R2.fastp-trim.20230215.fq.gz complete: C27_R2.blastx.meganized.daa

Now MEGANizing C27_R2.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: C27_R2.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 80% 100% (323.2s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.4s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (4,211.5s)
Total reads:       13,993,965
With hits:          13,993,965 
Alignments:      2,224,157,239
Assig. Taxonomy:    12,911,097
Assig. SEED:           149,125
Assig. EGGNOG:          90,973
Assig. GTDB:           463,194
Assig. EC:           2,121,859
Assig. INTERPRO2GO:  1,144,179
MinSupport set to: 6996
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.3s)
Min-supp. changes:       5,339
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (15.4s)
Min-supp. changes:       4,561
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (41.3s)
Binning reads Syncing
100% (0.4s)
Class. Taxonomy:            82
Class. SEED:               558
Class. EGGNOG:           1,962
Class. GTDB:                30
Class. EC:               2,587
Class. INTERPRO2GO:      8,002
Total time:  4,601s
Peak memory: 30.3 of 195.3G
MEGANization of C27_R2.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C28_R1.fastp-trim.20230215.fq.gz...
792dee1465274122b9e02cd7e28ae94b  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C28_R1.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C28_R1.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.327s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.705s]
Opening the output file...  [0s]
Loading query sequences...  [71.771s]
Masking queries...  [18.201s]
Algorithm: Double-indexed
Building query histograms...  [18.004s]
Loading reference sequences...  [29.809s]
Masking reference...  [30.913s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.567s]
Allocating buffers...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.046s]
Building query seed array...  [2.008s]
Computing hash join...  [5.091s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [72.858s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.284s]
Building query seed array...  [2.301s]
Computing hash join...  [5.022s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [44.536s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.128s]
Building query seed array...  [2.512s]
Computing hash join...  [5.029s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [40.399s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.816s]
Building query seed array...  [1.998s]
Computing hash join...  [4.986s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [34.571s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.695s]
Building query seed array...  [1.814s]
Computing hash join...  [4.811s]
Masking low complexity seeds...  [0.192s]
Searching alignments...  [35.991s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.976s]
Building query seed array...  [2.124s]
Computing hash join...  [4.734s]
Masking low complexity seeds...  [0.189s]
Searching alignments...  [28.873s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.282s]
Building query seed array...  [2.251s]
Computing hash join...  [4.822s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [33.072s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.007s]
Building query seed array...  [1.834s]
Computing hash join...  [4.796s]
Masking low complexity seeds...  [0.197s]
Searching alignments...  [27.675s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.122s]
Clearing query masking...  [1.567s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [10.744s]
Sorting trace points...  [2.184s]
Computing alignments...  [57.217s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.157s]
Sorting trace points...  [2.014s]
Computing alignments...  [56.834s]
Deallocating buffers...  [0.032s]
Loading trace points...  [0.066s]
Sorting trace points...  [2.189s]
Computing alignments...  [57.388s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.065s]
Sorting trace points...  [2.171s]
Computing alignments...  [56.217s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.075s]
Computing alignments...  [29.157s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.072s]
Sorting trace points...  [0.87s]
Computing alignments...  [29.886s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.041s]
Sorting trace points...  [0.827s]
Computing alignments...  [29.697s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.152s]
Computing alignments...  [29.702s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.055s]
Sorting trace points...  [0.983s]
Computing alignments...  [29.954s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.08s]
Computing alignments...  [29.885s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.172s]
Computing alignments...  [29.909s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.111s]
Computing alignments...  [29.609s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [494.922s]
Deallocating reference...  [0.074s]
Loading reference sequences...  [31.305s]
Masking reference...  [31.103s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [33.249s]
Allocating buffers...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.305s]
Building query seed array...  [2.062s]
Computing hash join...  [5.083s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [70.515s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.708s]
Building query seed array...  [2.336s]
Computing hash join...  [5.007s]
Masking low complexity seeds...  [0.2s]
Searching alignments...  [45.186s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.352s]
Building query seed array...  [2.436s]
Computing hash join...  [5.067s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [41.148s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.021s]
Building query seed array...  [2.004s]
Computing hash join...  [4.94s]
Masking low complexity seeds...  [0.193s]
Searching alignments...  [35.396s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.891s]
Building query seed array...  [1.854s]
Computing hash join...  [4.865s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [36.008s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.97s]
Building query seed array...  [2.169s]
Computing hash join...  [4.909s]
Masking low complexity seeds...  [0.191s]
Searching alignments...  [28.316s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.107s]
Building query seed array...  [2.088s]
Computing hash join...  [4.9s]
Masking low complexity seeds...  [0.193s]
Searching alignments...  [30.871s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.801s]
Building query seed array...  [1.782s]
Computing hash join...  [4.81s]
Masking low complexity seeds...  [0.192s]
Searching alignments...  [27.087s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.541s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [11.547s]
Sorting trace points...  [2.278s]
Computing alignments...  [56.734s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.144s]
Sorting trace points...  [1.707s]
Computing alignments...  [57.176s]
Deallocating buffers...  [0.04s]
Loading trace points...  [0.068s]
Sorting trace points...  [2.288s]
Computing alignments...  [57.147s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.039s]
Sorting trace points...  [1.728s]
Computing alignments...  [56.024s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.059s]
Computing alignments...  [28.908s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.061s]
Sorting trace points...  [0.88s]
Computing alignments...  [29.676s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.085s]
Sorting trace points...  [1.128s]
Computing alignments...  [29.789s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.081s]
Computing alignments...  [29.688s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.088s]
Computing alignments...  [29.826s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.04s]
Sorting trace points...  [1.13s]
Computing alignments...  [29.847s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.156s]
Computing alignments...  [29.896s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.053s]
Computing alignments...  [29.681s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0s]
 [493.476s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.591s]
Masking reference...  [30.92s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.57s]
Allocating buffers...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.019s]
Building query seed array...  [1.974s]
Computing hash join...  [5.018s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [74.131s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.329s]
Building query seed array...  [2.361s]
Computing hash join...  [5.175s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [44.406s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.432s]
Building query seed array...  [2.516s]
Computing hash join...  [4.963s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [39.548s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.208s]
Building query seed array...  [2.01s]
Computing hash join...  [4.978s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [35.261s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.985s]
Building query seed array...  [1.91s]
Computing hash join...  [4.765s]
Masking low complexity seeds...  [0.187s]
Searching alignments...  [36.785s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.036s]
Building query seed array...  [2.117s]
Computing hash join...  [4.824s]
Masking low complexity seeds...  [0.19s]
Searching alignments...  [28.736s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.147s]
Building query seed array...  [2.245s]
Computing hash join...  [4.933s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [32.71s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.689s]
Building query seed array...  [1.73s]
Computing hash join...  [4.894s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [28.321s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.575s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [11.411s]
Sorting trace points...  [2.152s]
Computing alignments...  [56.799s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.142s]
Sorting trace points...  [2.031s]
Computing alignments...  [56.995s]
Deallocating buffers...  [0.035s]
Loading trace points...  [0.138s]
Sorting trace points...  [1.942s]
Computing alignments...  [57.2s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.888s]
Computing alignments...  [56.173s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.041s]
Sorting trace points...  [0.87s]
Computing alignments...  [29.017s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.082s]
Computing alignments...  [29.678s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.07s]
Sorting trace points...  [0.938s]
Computing alignments...  [29.669s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.095s]
Computing alignments...  [29.676s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.128s]
Computing alignments...  [29.854s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.115s]
Computing alignments...  [29.898s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.078s]
Computing alignments...  [29.853s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.04s]
Computing alignments...  [29.576s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [493.269s]
Deallocating reference...  [0.066s]
Loading reference sequences...  [29.471s]
Masking reference...  [32.172s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.012s]
Allocating buffers...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.534s]
Building query seed array...  [2.017s]
Computing hash join...  [5.063s]
Masking low complexity seeds...  [0.2s]
Searching alignments...  [72.337s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.069s]
Building query seed array...  [2.377s]
Computing hash join...  [4.982s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [44.699s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.146s]
Building query seed array...  [2.433s]
Computing hash join...  [5.061s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [40.584s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.944s]
Building query seed array...  [2s]
Computing hash join...  [4.955s]
Masking low complexity seeds...  [0.198s]
Searching alignments...  [35.035s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.125s]
Building query seed array...  [1.809s]
Computing hash join...  [4.805s]
Masking low complexity seeds...  [0.198s]
Searching alignments...  [35.295s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.351s]
Building query seed array...  [2.107s]
Computing hash join...  [4.795s]
Masking low complexity seeds...  [0.194s]
Searching alignments...  [28.576s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.113s]
Building query seed array...  [2.213s]
Computing hash join...  [4.803s]
Masking low complexity seeds...  [0.195s]
Searching alignments...  [31.284s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.963s]
Building query seed array...  [1.782s]
Computing hash join...  [4.814s]
Masking low complexity seeds...  [0.197s]
Searching alignments...  [27.059s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.121s]
Clearing query masking...  [1.536s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [10.688s]
Sorting trace points...  [2.194s]
Computing alignments...  [56.773s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.174s]
Sorting trace points...  [2.085s]
Computing alignments...  [56.735s]
Deallocating buffers...  [0.039s]
Loading trace points...  [0.141s]
Sorting trace points...  [2.268s]
Computing alignments...  [57.188s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.772s]
Computing alignments...  [55.875s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.111s]
Computing alignments...  [28.916s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.091s]
Sorting trace points...  [1.034s]
Computing alignments...  [29.579s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.002s]
Sorting trace points...  [0.903s]
Computing alignments...  [29.509s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.139s]
Computing alignments...  [29.645s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.136s]
Computing alignments...  [29.826s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.122s]
Computing alignments...  [29.872s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.141s]
Computing alignments...  [29.799s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0s]
Sorting trace points...  [0.997s]
Computing alignments...  [29.497s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
 [491.911s]
Deallocating reference...  [0.07s]
Loading reference sequences...  [29.547s]
Masking reference...  [32.114s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.149s]
Allocating buffers...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.278s]
Building query seed array...  [2.052s]
Computing hash join...  [5.097s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [72.12s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.38s]
Building query seed array...  [2.368s]
Computing hash join...  [5.17s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [43.514s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.993s]
Building query seed array...  [2.462s]
Computing hash join...  [5.014s]
Masking low complexity seeds...  [0.199s]
Searching alignments...  [38.736s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.828s]
Building query seed array...  [1.981s]
Computing hash join...  [5.041s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [35.154s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.015s]
Building query seed array...  [1.865s]
Computing hash join...  [4.805s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [36.295s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.406s]
Building query seed array...  [2.113s]
Computing hash join...  [4.776s]
Masking low complexity seeds...  [0.191s]
Searching alignments...  [28.259s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.18s]
Building query seed array...  [2.221s]
Computing hash join...  [4.815s]
Masking low complexity seeds...  [0.196s]
Searching alignments...  [32.055s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.942s]
Building query seed array...  [1.77s]
Computing hash join...  [4.845s]
Masking low complexity seeds...  [0.187s]
Searching alignments...  [27.082s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.121s]
Clearing query masking...  [1.528s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [11.47s]
Sorting trace points...  [2.224s]
Computing alignments...  [56.745s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.141s]
Sorting trace points...  [1.746s]
Computing alignments...  [56.422s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0.125s]
Sorting trace points...  [1.99s]
Computing alignments...  [56.924s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.881s]
Computing alignments...  [55.74s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.077s]
Computing alignments...  [28.854s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.074s]
Sorting trace points...  [0.984s]
Computing alignments...  [29.56s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.119s]
Computing alignments...  [29.473s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.076s]
Computing alignments...  [29.545s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.056s]
Sorting trace points...  [0.882s]
Computing alignments...  [29.787s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.091s]
Computing alignments...  [29.706s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.109s]
Computing alignments...  [29.736s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [0.964s]
Computing alignments...  [29.312s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [490.474s]
Deallocating reference...  [0.07s]
Loading reference sequences...  [33.013s]
Masking reference...  [32.006s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.323s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.082s]
Building query seed array...  [1.986s]
Computing hash join...  [5.013s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [69.445s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.134s]
Building query seed array...  [2.268s]
Computing hash join...  [5.018s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [44.865s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.693s]
Building query seed array...  [2.463s]
Computing hash join...  [4.974s]
Masking low complexity seeds...  [0.195s]
Searching alignments...  [39.416s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.985s]
Building query seed array...  [2.018s]
Computing hash join...  [4.969s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [34.477s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.817s]
Building query seed array...  [1.822s]
Computing hash join...  [4.84s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [35.411s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.469s]
Building query seed array...  [2.119s]
Computing hash join...  [4.854s]
Masking low complexity seeds...  [0.183s]
Searching alignments...  [28.966s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.739s]
Building query seed array...  [2.198s]
Computing hash join...  [4.912s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [30.618s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.894s]
Building query seed array...  [1.771s]
Computing hash join...  [4.771s]
Masking low complexity seeds...  [0.188s]
Searching alignments...  [26.621s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.527s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [11.543s]
Sorting trace points...  [2.273s]
Computing alignments...  [56.652s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.147s]
Sorting trace points...  [2.19s]
Computing alignments...  [56.351s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.173s]
Sorting trace points...  [2.078s]
Computing alignments...  [56.892s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.972s]
Computing alignments...  [55.775s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.09s]
Sorting trace points...  [0.86s]
Computing alignments...  [28.809s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.149s]
Computing alignments...  [29.465s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.098s]
Computing alignments...  [29.448s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.116s]
Computing alignments...  [29.538s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.001s]
Sorting trace points...  [0.842s]
Computing alignments...  [29.728s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.062s]
Sorting trace points...  [0.957s]
Computing alignments...  [29.598s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.166s]
Computing alignments...  [29.632s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.126s]
Computing alignments...  [29.36s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [490.891s]
Deallocating reference...  [0.065s]
Loading reference sequences...  [29.514s]
Masking reference...  [30.841s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.542s]
Allocating buffers...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.443s]
Building query seed array...  [1.973s]
Computing hash join...  [4.971s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [73.699s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.092s]
Building query seed array...  [2.298s]
Computing hash join...  [4.995s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [44.568s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.298s]
Building query seed array...  [2.43s]
Computing hash join...  [4.947s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [39.827s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.01s]
Building query seed array...  [1.999s]
Computing hash join...  [4.934s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [35.031s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.042s]
Building query seed array...  [1.828s]
Computing hash join...  [4.758s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [36.155s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.86s]
Building query seed array...  [2.195s]
Computing hash join...  [4.817s]
Masking low complexity seeds...  [0.191s]
Searching alignments...  [28.391s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.081s]
Building query seed array...  [2.148s]
Computing hash join...  [4.776s]
Masking low complexity seeds...  [0.184s]
Searching alignments...  [32.239s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.275s]
Building query seed array...  [1.82s]
Computing hash join...  [4.87s]
Masking low complexity seeds...  [0.194s]
Searching alignments...  [27.366s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.495s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [10.684s]
Sorting trace points...  [2.315s]
Computing alignments...  [56.539s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.147s]
Sorting trace points...  [2.09s]
Computing alignments...  [56.436s]
Deallocating buffers...  [0.036s]
Loading trace points...  [0.155s]
Sorting trace points...  [2.262s]
Computing alignments...  [56.945s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.976s]
Computing alignments...  [55.838s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.039s]
Sorting trace points...  [1.117s]
Computing alignments...  [28.825s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.063s]
Sorting trace points...  [0.984s]
Computing alignments...  [29.629s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.091s]
Computing alignments...  [29.463s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.118s]
Computing alignments...  [29.638s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.141s]
Computing alignments...  [29.793s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.139s]
Computing alignments...  [29.81s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.129s]
Computing alignments...  [29.79s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.119s]
Computing alignments...  [29.452s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [491.371s]
Deallocating reference...  [0.068s]
Loading reference sequences...  [29.713s]
Masking reference...  [30.811s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.579s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.174s]
Building query seed array...  [2.032s]
Computing hash join...  [4.997s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [73.129s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.197s]
Building query seed array...  [2.348s]
Computing hash join...  [4.995s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [45.888s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [14.009s]
Building query seed array...  [2.501s]
Computing hash join...  [4.954s]
Masking low complexity seeds...  [0.199s]
Searching alignments...  [41.144s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.717s]
Building query seed array...  [1.996s]
Computing hash join...  [4.969s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [37.137s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.112s]
Building query seed array...  [1.871s]
Computing hash join...  [4.786s]
Masking low complexity seeds...  [0.193s]
Searching alignments...  [35.69s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.509s]
Building query seed array...  [2.125s]
Computing hash join...  [4.729s]
Masking low complexity seeds...  [0.191s]
Searching alignments...  [29.679s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.427s]
Building query seed array...  [2.167s]
Computing hash join...  [4.761s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [31.452s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.786s]
Building query seed array...  [1.783s]
Computing hash join...  [4.852s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [27.417s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.531s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [11.42s]
Sorting trace points...  [2.221s]
Computing alignments...  [57.01s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.144s]
Sorting trace points...  [2.182s]
Computing alignments...  [56.542s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.757s]
Sorting trace points...  [2.205s]
Computing alignments...  [57.113s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.686s]
Sorting trace points...  [2.134s]
Computing alignments...  [55.999s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.102s]
Computing alignments...  [28.99s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.116s]
Computing alignments...  [29.676s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.847s]
Sorting trace points...  [0.934s]
Computing alignments...  [29.573s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.086s]
Computing alignments...  [29.619s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.162s]
Computing alignments...  [29.771s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.12s]
Computing alignments...  [29.808s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.079s]
Computing alignments...  [29.811s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.104s]
Computing alignments...  [29.448s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [495.373s]
Deallocating reference...  [0.065s]
Loading reference sequences...  [35.308s]
Masking reference...  [31.005s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.006s]
Building reference histograms...  [32.902s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.095s]
Building query seed array...  [2.036s]
Computing hash join...  [5.025s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [69.957s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.292s]
Building query seed array...  [2.272s]
Computing hash join...  [5.112s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [44.471s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.62s]
Building query seed array...  [2.453s]
Computing hash join...  [4.916s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [41.641s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.843s]
Building query seed array...  [1.967s]
Computing hash join...  [4.949s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [36.415s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.235s]
Building query seed array...  [1.814s]
Computing hash join...  [4.78s]
Masking low complexity seeds...  [0.198s]
Searching alignments...  [35.802s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.153s]
Building query seed array...  [2.123s]
Computing hash join...  [4.79s]
Masking low complexity seeds...  [0.195s]
Searching alignments...  [28.339s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.526s]
Building query seed array...  [2.176s]
Computing hash join...  [4.825s]
Masking low complexity seeds...  [0.199s]
Searching alignments...  [31.306s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.084s]
Building query seed array...  [1.771s]
Computing hash join...  [4.845s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [27.33s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.128s]
Clearing query masking...  [1.538s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [10.713s]
Sorting trace points...  [2.263s]
Computing alignments...  [56.467s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.134s]
Sorting trace points...  [1.75s]
Computing alignments...  [56.325s]
Deallocating buffers...  [0.035s]
Loading trace points...  [0.136s]
Sorting trace points...  [2.107s]
Computing alignments...  [56.785s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.638s]
Computing alignments...  [55.706s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.059s]
Computing alignments...  [28.859s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.067s]
Sorting trace points...  [0.831s]
Computing alignments...  [29.555s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [0.957s]
Computing alignments...  [29.446s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.131s]
Computing alignments...  [29.616s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.06s]
Sorting trace points...  [0.891s]
Computing alignments...  [29.742s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.125s]
Computing alignments...  [29.718s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.043s]
Sorting trace points...  [0.949s]
Computing alignments...  [29.675s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.103s]
Computing alignments...  [29.392s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [488.787s]
Deallocating reference...  [0.067s]
Loading reference sequences...  [30.769s]
Masking reference...  [32.16s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [31.648s]
Allocating buffers...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.123s]
Building query seed array...  [1.974s]
Computing hash join...  [5.057s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [71.803s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.593s]
Building query seed array...  [2.306s]
Computing hash join...  [5.036s]
Masking low complexity seeds...  [0.197s]
Searching alignments...  [44.002s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.323s]
Building query seed array...  [2.444s]
Computing hash join...  [4.914s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [38.841s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.43s]
Building query seed array...  [2.052s]
Computing hash join...  [5.005s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [35.188s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.88s]
Building query seed array...  [1.846s]
Computing hash join...  [4.81s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [36.759s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.445s]
Building query seed array...  [2.161s]
Computing hash join...  [4.801s]
Masking low complexity seeds...  [0.195s]
Searching alignments...  [29.104s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.209s]
Building query seed array...  [2.196s]
Computing hash join...  [4.787s]
Masking low complexity seeds...  [0.194s]
Searching alignments...  [32.168s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.813s]
Building query seed array...  [1.769s]
Computing hash join...  [4.829s]
Masking low complexity seeds...  [0.187s]
Searching alignments...  [27.583s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.14s]
Clearing query masking...  [1.53s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [11.381s]
Sorting trace points...  [2.18s]
Computing alignments...  [56.815s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.145s]
Sorting trace points...  [2.229s]
Computing alignments...  [56.388s]
Deallocating buffers...  [0.032s]
Loading trace points...  [0.156s]
Sorting trace points...  [2.026s]
Computing alignments...  [56.979s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.916s]
Computing alignments...  [55.801s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.046s]
Computing alignments...  [28.84s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.088s]
Computing alignments...  [29.585s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.075s]
Sorting trace points...  [0.964s]
Computing alignments...  [29.476s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.099s]
Computing alignments...  [29.526s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.079s]
Sorting trace points...  [0.848s]
Computing alignments...  [29.805s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.086s]
Computing alignments...  [29.758s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.023s]
Computing alignments...  [29.763s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1s]
Computing alignments...  [29.443s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
 [491.133s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [32.331s]
Masking reference...  [32.077s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [31.598s]
Allocating buffers...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.601s]
Building query seed array...  [2.02s]
Computing hash join...  [5.003s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [68s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.218s]
Building query seed array...  [2.374s]
Computing hash join...  [5.096s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [45.226s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.341s]
Building query seed array...  [2.552s]
Computing hash join...  [4.928s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [39.886s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.263s]
Building query seed array...  [2.007s]
Computing hash join...  [4.959s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [36.05s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.737s]
Building query seed array...  [1.838s]
Computing hash join...  [4.751s]
Masking low complexity seeds...  [0.188s]
Searching alignments...  [35.138s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.253s]
Building query seed array...  [2.139s]
Computing hash join...  [4.8s]
Masking low complexity seeds...  [0.184s]
Searching alignments...  [27.989s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.435s]
Building query seed array...  [2.26s]
Computing hash join...  [4.937s]
Masking low complexity seeds...  [0.192s]
Searching alignments...  [30.663s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.877s]
Building query seed array...  [1.873s]
Computing hash join...  [4.817s]
Masking low complexity seeds...  [0.195s]
Searching alignments...  [26.477s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.594s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [11.417s]
Sorting trace points...  [2.238s]
Computing alignments...  [56.376s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.108s]
Sorting trace points...  [1.992s]
Computing alignments...  [56.696s]
Deallocating buffers...  [0.036s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.836s]
Computing alignments...  [57.09s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.001s]
Sorting trace points...  [2.172s]
Computing alignments...  [55.687s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.03s]
Computing alignments...  [28.923s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.088s]
Computing alignments...  [29.503s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.077s]
Computing alignments...  [29.607s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.122s]
Computing alignments...  [29.475s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.109s]
Computing alignments...  [29.611s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.107s]
Computing alignments...  [29.673s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.104s]
Computing alignments...  [29.68s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0s]
Sorting trace points...  [1.119s]
Computing alignments...  [29.37s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0s]
 [491.103s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [29.631s]
Masking reference...  [32.137s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.755s]
Allocating buffers...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.251s]
Building query seed array...  [1.99s]
Computing hash join...  [5.13s]
Masking low complexity seeds...  [0.2s]
Searching alignments...  [72.386s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.626s]
Building query seed array...  [2.307s]
Computing hash join...  [4.951s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [43.727s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.233s]
Building query seed array...  [2.454s]
Computing hash join...  [4.903s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [38.832s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.98s]
Building query seed array...  [1.943s]
Computing hash join...  [4.965s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [34.781s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.98s]
Building query seed array...  [1.901s]
Computing hash join...  [4.829s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [35.408s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.499s]
Building query seed array...  [2.13s]
Computing hash join...  [4.782s]
Masking low complexity seeds...  [0.2s]
Searching alignments...  [29.56s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.299s]
Building query seed array...  [2.171s]
Computing hash join...  [4.794s]
Masking low complexity seeds...  [0.191s]
Searching alignments...  [33.08s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.935s]
Building query seed array...  [1.78s]
Computing hash join...  [4.769s]
Masking low complexity seeds...  [0.189s]
Searching alignments...  [26.927s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.538s]
Opening temporary output file...  [0.002s]
Computing alignments... Loading trace points...  [12.088s]
Sorting trace points...  [2.182s]
Computing alignments...  [56.915s]
Deallocating buffers...  [0.032s]
Loading trace points...  [0.138s]
Sorting trace points...  [2.171s]
Computing alignments...  [56.547s]
Deallocating buffers...  [0.036s]
Loading trace points...  [0.11s]
Sorting trace points...  [1.813s]
Computing alignments...  [57.149s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.059s]
Sorting trace points...  [2.02s]
Computing alignments...  [55.875s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.039s]
Sorting trace points...  [1.058s]
Computing alignments...  [28.879s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.087s]
Sorting trace points...  [1.126s]
Computing alignments...  [29.643s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.111s]
Computing alignments...  [29.484s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.067s]
Sorting trace points...  [0.982s]
Computing alignments...  [29.561s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.117s]
Computing alignments...  [29.84s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.039s]
Sorting trace points...  [0.925s]
Computing alignments...  [29.816s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.077s]
Sorting trace points...  [0.936s]
Computing alignments...  [29.836s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.114s]
Computing alignments...  [29.476s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
 [492.689s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.51s]
Masking reference...  [32.119s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.006s]
Building reference histograms...  [32.183s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.103s]
Building query seed array...  [1.983s]
Computing hash join...  [4.895s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [70.619s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.486s]
Building query seed array...  [2.423s]
Computing hash join...  [5.024s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [45.775s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.35s]
Building query seed array...  [2.446s]
Computing hash join...  [4.985s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [39.97s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.302s]
Building query seed array...  [1.941s]
Computing hash join...  [4.937s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [36.335s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.042s]
Building query seed array...  [1.827s]
Computing hash join...  [4.796s]
Masking low complexity seeds...  [0.196s]
Searching alignments...  [35.354s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.75s]
Building query seed array...  [2.082s]
Computing hash join...  [4.715s]
Masking low complexity seeds...  [0.189s]
Searching alignments...  [28.353s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.119s]
Building query seed array...  [2.261s]
Computing hash join...  [4.784s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [31.741s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.698s]
Building query seed array...  [1.787s]
Computing hash join...  [4.901s]
Masking low complexity seeds...  [0.191s]
Searching alignments...  [27.326s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.122s]
Clearing query masking...  [1.467s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [10.689s]
Sorting trace points...  [2.193s]
Computing alignments...  [56.583s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.136s]
Sorting trace points...  [1.912s]
Computing alignments...  [56.676s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.086s]
Sorting trace points...  [2.239s]
Computing alignments...  [56.905s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.044s]
Sorting trace points...  [2.058s]
Computing alignments...  [55.654s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.094s]
Computing alignments...  [28.703s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.115s]
Computing alignments...  [29.473s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.085s]
Sorting trace points...  [1.108s]
Computing alignments...  [29.527s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.064s]
Sorting trace points...  [0.841s]
Computing alignments...  [29.528s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.112s]
Computing alignments...  [29.714s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.11s]
Computing alignments...  [29.669s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.067s]
Sorting trace points...  [0.86s]
Computing alignments...  [29.703s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [0.91s]
Computing alignments...  [29.389s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
 [489.889s]
Deallocating reference...  [0.068s]
Loading reference sequences...  [25.677s]
Masking reference...  [26.13s]
Initializing dictionary...  [0.063s]
Initializing temporary storage...  [0.006s]
Building reference histograms...  [25.95s]
Allocating buffers...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.718s]
Building query seed array...  [1.982s]
Computing hash join...  [4.148s]
Masking low complexity seeds...  [0.197s]
Searching alignments...  [57.193s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [10.404s]
Building query seed array...  [2.247s]
Computing hash join...  [4.203s]
Masking low complexity seeds...  [0.197s]
Searching alignments...  [37.395s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [10.724s]
Building query seed array...  [2.584s]
Computing hash join...  [4.171s]
Masking low complexity seeds...  [0.19s]
Searching alignments...  [32.122s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [8.089s]
Building query seed array...  [1.999s]
Computing hash join...  [4.162s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [28.178s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [8.247s]
Building query seed array...  [1.76s]
Computing hash join...  [4.03s]
Masking low complexity seeds...  [0.193s]
Searching alignments...  [29.415s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [9.898s]
Building query seed array...  [2.145s]
Computing hash join...  [4.077s]
Masking low complexity seeds...  [0.181s]
Searching alignments...  [23.576s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [10.804s]
Building query seed array...  [2.18s]
Computing hash join...  [4.073s]
Masking low complexity seeds...  [0.185s]
Searching alignments...  [25.696s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [8.279s]
Building query seed array...  [1.839s]
Computing hash join...  [3.937s]
Masking low complexity seeds...  [0.191s]
Searching alignments...  [22.246s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.103s]
Clearing query masking...  [1.476s]
Opening temporary output file...  [0.029s]
Computing alignments... Loading trace points...  [9.805s]
Sorting trace points...  [1.822s]
Computing alignments...  [45.087s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.137s]
Sorting trace points...  [1.848s]
Computing alignments...  [44.974s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.101s]
Sorting trace points...  [1.442s]
Computing alignments...  [45.403s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.662s]
Computing alignments...  [44.738s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.17s]
Sorting trace points...  [1.45s]
Computing alignments...  [46.544s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.107s]
Sorting trace points...  [1.523s]
Computing alignments...  [46.961s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.153s]
Sorting trace points...  [1.43s]
Computing alignments...  [47.456s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
Sorting trace points...  [1.675s]
Computing alignments...  [46.957s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0s]
 [391.849s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [0.087s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [1788.11s]
 [1788.11s]
Deallocating queries...  [0.048s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [3.657s]
 [4.669s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 16443s
Reported 2306711267 pairwise alignments, 2306711267 HSPs.
12689987 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C28_R1.fastp-trim.20230215.fq.gz complete: C28_R1.blastx.meganized.daa

Now MEGANizing C28_R1.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: C28_R1.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 100% (226.9s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.1s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (4,450.1s)
Total reads:       12,689,987
With hits:          12,689,987 
Alignments:      2,302,232,731
Assig. Taxonomy:    12,007,803
Assig. SEED:            90,389
Assig. EGGNOG:          43,872
Assig. GTDB:           362,110
Assig. EC:           2,062,380
Assig. INTERPRO2GO:  1,048,735
MinSupport set to: 6344
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.5s)
Min-supp. changes:       3,635
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (8.0s)
Min-supp. changes:       2,736
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (27.1s)
Binning reads Syncing
100% (0.3s)
Class. Taxonomy:            62
Class. SEED:               485
Class. EGGNOG:           1,741
Class. GTDB:                19
Class. EC:               2,297
Class. INTERPRO2GO:      7,593
Total time:  4,722s
Peak memory: 31.4 of 195.3G
MEGANization of C28_R1.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C28_R2.fastp-trim.20230215.fq.gz...
ef83fc36ff7c6cb4f000915084523b6e  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C28_R2.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C28_R2.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.319s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.712s]
Opening the output file...  [0s]
Loading query sequences...  [73.423s]
Masking queries...  [18.49s]
Algorithm: Double-indexed
Building query histograms...  [20.541s]
Loading reference sequences...  [29.499s]
Masking reference...  [32.14s]
Initializing dictionary...  [0.08s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.581s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.275s]
Building query seed array...  [2.08s]
Computing hash join...  [5.576s]
Masking low complexity seeds...  [0.345s]
Searching alignments...  [71.557s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.257s]
Building query seed array...  [2.325s]
Computing hash join...  [5.047s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [45.924s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.523s]
Building query seed array...  [2.424s]
Computing hash join...  [5.059s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [39.761s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.008s]
Building query seed array...  [2.009s]
Computing hash join...  [5.202s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [35.528s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.829s]
Building query seed array...  [1.851s]
Computing hash join...  [4.918s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [39.025s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.832s]
Building query seed array...  [2.092s]
Computing hash join...  [4.942s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [30.781s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.657s]
Building query seed array...  [2.179s]
Computing hash join...  [4.953s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [33.124s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.08s]
Building query seed array...  [1.784s]
Computing hash join...  [4.878s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [27.742s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.131s]
Clearing query masking...  [1.599s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [10.65s]
Sorting trace points...  [2.22s]
Computing alignments...  [56.38s]
Deallocating buffers...  [0.026s]
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Sorting trace points...  [1.645s]
Computing alignments...  [56.475s]
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Sorting trace points...  [1.889s]
Computing alignments...  [55.766s]
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Sorting trace points...  [2.074s]
Computing alignments...  [55.576s]
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Sorting trace points...  [1.014s]
Computing alignments...  [29.066s]
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Sorting trace points...  [0.868s]
Computing alignments...  [30.242s]
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Computing alignments...  [30.209s]
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Computing alignments...  [30.288s]
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Computing alignments...  [30.526s]
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Computing alignments...  [30.452s]
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Computing alignments...  [30.501s]
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Computing alignments...  [30.324s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
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Deallocating reference...  [0.061s]
Loading reference sequences...  [29.477s]
Masking reference...  [30.919s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.951s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.674s]
Building query seed array...  [2.024s]
Computing hash join...  [5.183s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [69.949s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [11.943s]
Building query seed array...  [2.325s]
Computing hash join...  [5.068s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [45.239s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.496s]
Building query seed array...  [2.491s]
Computing hash join...  [5.124s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [40.525s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.217s]
Building query seed array...  [2.05s]
Computing hash join...  [5.195s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [37.1s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.943s]
Building query seed array...  [1.884s]
Computing hash join...  [4.95s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [38.36s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.104s]
Building query seed array...  [2.108s]
Computing hash join...  [4.879s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [29.474s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.393s]
Building query seed array...  [2.269s]
Computing hash join...  [4.96s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [32.025s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.987s]
Building query seed array...  [1.822s]
Computing hash join...  [4.953s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [27.833s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.55s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [11.348s]
Sorting trace points...  [2.236s]
Computing alignments...  [56.277s]
Deallocating buffers...  [0.025s]
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Sorting trace points...  [1.712s]
Computing alignments...  [56.229s]
Deallocating buffers...  [0.027s]
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Sorting trace points...  [1.647s]
Computing alignments...  [55.659s]
Deallocating buffers...  [0.027s]
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Sorting trace points...  [1.669s]
Computing alignments...  [55.531s]
Deallocating buffers...  [0.027s]
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Sorting trace points...  [0.849s]
Computing alignments...  [29.041s]
Deallocating buffers...  [0.014s]
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Sorting trace points...  [1.108s]
Computing alignments...  [30.672s]
Deallocating buffers...  [0.014s]
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Sorting trace points...  [0.946s]
Computing alignments...  [30.164s]
Deallocating buffers...  [0.014s]
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Sorting trace points...  [0.945s]
Computing alignments...  [30.179s]
Deallocating buffers...  [0.015s]
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Sorting trace points...  [0.945s]
Computing alignments...  [30.424s]
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Computing alignments...  [30.445s]
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Computing alignments...  [30.511s]
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Computing alignments...  [30.058s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [492.973s]
Deallocating reference...  [0.071s]
Loading reference sequences...  [29.642s]
Masking reference...  [32.185s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.792s]
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Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.528s]
Building query seed array...  [1.976s]
Computing hash join...  [5.23s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [72.001s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.465s]
Building query seed array...  [2.393s]
Computing hash join...  [5.115s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [45.346s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.193s]
Building query seed array...  [2.404s]
Computing hash join...  [5.046s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [41.715s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.285s]
Building query seed array...  [2.038s]
Computing hash join...  [5.154s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [36.43s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.929s]
Building query seed array...  [1.809s]
Computing hash join...  [4.973s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [39.319s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.664s]
Building query seed array...  [2.117s]
Computing hash join...  [4.951s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [30.087s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.31s]
Building query seed array...  [2.28s]
Computing hash join...  [5.01s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [32.458s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.999s]
Building query seed array...  [1.837s]
Computing hash join...  [4.913s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [28.264s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.135s]
Clearing query masking...  [1.6s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [12.004s]
Sorting trace points...  [2.219s]
Computing alignments...  [56.154s]
Deallocating buffers...  [0.025s]
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Sorting trace points...  [1.813s]
Computing alignments...  [56.163s]
Deallocating buffers...  [0.029s]
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Sorting trace points...  [1.746s]
Computing alignments...  [55.497s]
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Loading trace points...  [0.053s]
Sorting trace points...  [2.134s]
Computing alignments...  [55.326s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.086s]
Computing alignments...  [28.969s]
Deallocating buffers...  [0.013s]
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Sorting trace points...  [1.147s]
Computing alignments...  [30.13s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.146s]
Computing alignments...  [30.017s]
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Sorting trace points...  [1.03s]
Computing alignments...  [30.167s]
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Computing alignments...  [30.372s]
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Sorting trace points...  [1.114s]
Computing alignments...  [30.301s]
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Sorting trace points...  [1.146s]
Computing alignments...  [30.276s]
Deallocating buffers...  [0.022s]
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Sorting trace points...  [0.884s]
Computing alignments...  [29.954s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [493.076s]
Deallocating reference...  [0.066s]
Loading reference sequences...  [34.83s]
Masking reference...  [31.765s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.884s]
Allocating buffers...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.747s]
Building query seed array...  [1.936s]
Computing hash join...  [5.086s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [69.79s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.314s]
Building query seed array...  [2.408s]
Computing hash join...  [5.097s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [43.551s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.302s]
Building query seed array...  [2.501s]
Computing hash join...  [5.062s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [38.828s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.875s]
Building query seed array...  [2.008s]
Computing hash join...  [5.225s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [34.851s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.014s]
Building query seed array...  [1.783s]
Computing hash join...  [4.96s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [38.02s]
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Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.395s]
Building query seed array...  [2.105s]
Computing hash join...  [4.905s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [29.855s]
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Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.867s]
Building query seed array...  [2.226s]
Computing hash join...  [4.878s]
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Searching alignments...  [32.058s]
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Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.169s]
Building query seed array...  [1.781s]
Computing hash join...  [4.925s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [27.346s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.122s]
Clearing query masking...  [1.539s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [11.58s]
Sorting trace points...  [2.254s]
Computing alignments...  [56.408s]
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Sorting trace points...  [2.167s]
Computing alignments...  [56.195s]
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Sorting trace points...  [2.008s]
Computing alignments...  [55.588s]
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Computing alignments...  [55.444s]
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Sorting trace points...  [1.08s]
Computing alignments...  [29.062s]
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Loading trace points...  [0.064s]
Sorting trace points...  [1.144s]
Computing alignments...  [30.192s]
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Computing alignments...  [30.047s]
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Computing alignments...  [30.237s]
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Computing alignments...  [30.542s]
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Computing alignments...  [30.327s]
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Computing alignments...  [30.334s]
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Computing alignments...  [30.027s]
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 [494.034s]
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Loading reference sequences...  [34.728s]
Masking reference...  [30.885s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [33.631s]
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Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.374s]
Building query seed array...  [2.012s]
Computing hash join...  [5.11s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [70.432s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.81s]
Building query seed array...  [2.307s]
Computing hash join...  [5.142s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [45.38s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.579s]
Building query seed array...  [2.529s]
Computing hash join...  [5.115s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [39.901s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.534s]
Building query seed array...  [2.026s]
Computing hash join...  [5.146s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [35.529s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.238s]
Building query seed array...  [1.882s]
Computing hash join...  [4.96s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [38.407s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.502s]
Building query seed array...  [2.11s]
Computing hash join...  [4.892s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [30.489s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.595s]
Building query seed array...  [2.313s]
Computing hash join...  [4.945s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [31.994s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.135s]
Building query seed array...  [1.824s]
Computing hash join...  [4.872s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [27.183s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.525s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [11.371s]
Sorting trace points...  [2.172s]
Computing alignments...  [56.383s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.103s]
Sorting trace points...  [1.789s]
Computing alignments...  [56.29s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.147s]
Sorting trace points...  [2.129s]
Computing alignments...  [55.632s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.76s]
Computing alignments...  [55.725s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0s]
Sorting trace points...  [1.086s]
Computing alignments...  [29.069s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.157s]
Computing alignments...  [30.327s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.068s]
Computing alignments...  [30.24s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.057s]
Sorting trace points...  [0.901s]
Computing alignments...  [30.255s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.159s]
Computing alignments...  [30.428s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.127s]
Computing alignments...  [30.333s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.167s]
Computing alignments...  [30.326s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0s]
Sorting trace points...  [1.154s]
Computing alignments...  [30.19s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
 [494.723s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.62s]
Masking reference...  [32.202s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.63s]
Allocating buffers...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.336s]
Building query seed array...  [2.078s]
Computing hash join...  [5.196s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [68.428s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.118s]
Building query seed array...  [2.361s]
Computing hash join...  [5.11s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [43.717s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.819s]
Building query seed array...  [2.461s]
Computing hash join...  [5.098s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [41.751s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.213s]
Building query seed array...  [1.989s]
Computing hash join...  [5.17s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [34.6s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.164s]
Building query seed array...  [1.812s]
Computing hash join...  [4.863s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [36.385s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.237s]
Building query seed array...  [2.178s]
Computing hash join...  [4.963s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [29.344s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.901s]
Building query seed array...  [2.285s]
Computing hash join...  [4.911s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [30.924s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.996s]
Building query seed array...  [1.899s]
Computing hash join...  [4.903s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [26.772s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.525s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [11.361s]
Sorting trace points...  [2.215s]
Computing alignments...  [55.861s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.11s]
Sorting trace points...  [1.74s]
Computing alignments...  [55.875s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.165s]
Sorting trace points...  [2.084s]
Computing alignments...  [54.932s]
Deallocating buffers...  [0.035s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.561s]
Computing alignments...  [55s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.095s]
Computing alignments...  [29.281s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.096s]
Sorting trace points...  [1.119s]
Computing alignments...  [30.017s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.139s]
Computing alignments...  [29.863s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.079s]
Sorting trace points...  [0.94s]
Computing alignments...  [29.987s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.143s]
Computing alignments...  [30.247s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.119s]
Computing alignments...  [30.178s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.156s]
Computing alignments...  [30.2s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0s]
Sorting trace points...  [1.128s]
Computing alignments...  [29.863s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [490.354s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.499s]
Masking reference...  [32.121s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.808s]
Allocating buffers...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.757s]
Building query seed array...  [2.032s]
Computing hash join...  [5.111s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [70.891s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.441s]
Building query seed array...  [2.3s]
Computing hash join...  [5.146s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [44.337s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.63s]
Building query seed array...  [2.454s]
Computing hash join...  [5.103s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [39.982s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.924s]
Building query seed array...  [2.046s]
Computing hash join...  [5.127s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [34.95s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.231s]
Building query seed array...  [1.881s]
Computing hash join...  [4.978s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [38.93s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.82s]
Building query seed array...  [2.104s]
Computing hash join...  [4.888s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [29.727s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.298s]
Building query seed array...  [2.334s]
Computing hash join...  [4.988s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [33.006s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.328s]
Building query seed array...  [1.783s]
Computing hash join...  [4.999s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [29.335s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.128s]
Clearing query masking...  [1.48s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [11.631s]
Sorting trace points...  [2.285s]
Computing alignments...  [56.312s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.121s]
Sorting trace points...  [1.909s]
Computing alignments...  [56.461s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.142s]
Sorting trace points...  [2.113s]
Computing alignments...  [55.556s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.064s]
Sorting trace points...  [2.119s]
Computing alignments...  [55.504s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.044s]
Sorting trace points...  [0.814s]
Computing alignments...  [29.111s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.121s]
Computing alignments...  [30.267s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.084s]
Sorting trace points...  [0.909s]
Computing alignments...  [30.095s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.068s]
Sorting trace points...  [0.892s]
Computing alignments...  [30.29s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.154s]
Computing alignments...  [30.51s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.063s]
Sorting trace points...  [0.995s]
Computing alignments...  [30.366s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.128s]
Computing alignments...  [30.304s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0s]
Sorting trace points...  [0.929s]
Computing alignments...  [30.037s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [494.051s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.733s]
Masking reference...  [32.084s]
Initializing dictionary...  [0.08s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.877s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.426s]
Building query seed array...  [2.016s]
Computing hash join...  [5.195s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [69.535s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.247s]
Building query seed array...  [2.329s]
Computing hash join...  [5.14s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [45.278s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [14.009s]
Building query seed array...  [2.56s]
Computing hash join...  [5.019s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [40.389s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.111s]
Building query seed array...  [1.968s]
Computing hash join...  [5.122s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [36.145s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.005s]
Building query seed array...  [1.893s]
Computing hash join...  [4.949s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [38.124s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.378s]
Building query seed array...  [2.101s]
Computing hash join...  [4.96s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [30.675s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.189s]
Building query seed array...  [2.301s]
Computing hash join...  [4.935s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [32.254s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.679s]
Building query seed array...  [1.822s]
Computing hash join...  [5.119s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [27.407s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.495s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [10.733s]
Sorting trace points...  [2.22s]
Computing alignments...  [56.153s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.173s]
Sorting trace points...  [2.122s]
Computing alignments...  [56.344s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.145s]
Sorting trace points...  [1.732s]
Computing alignments...  [55.511s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.362s]
Sorting trace points...  [1.973s]
Computing alignments...  [55.476s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.835s]
Sorting trace points...  [1.145s]
Computing alignments...  [29.042s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.135s]
Computing alignments...  [30.23s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.166s]
Computing alignments...  [30.171s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.166s]
Computing alignments...  [30.285s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.118s]
Computing alignments...  [30.533s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.176s]
Computing alignments...  [30.401s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.167s]
Computing alignments...  [30.375s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.139s]
Computing alignments...  [30.062s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [494.837s]
Deallocating reference...  [0.066s]
Loading reference sequences...  [34.158s]
Masking reference...  [31.488s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.984s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.437s]
Building query seed array...  [2.092s]
Computing hash join...  [5.114s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [67.577s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.511s]
Building query seed array...  [2.346s]
Computing hash join...  [5.112s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [46.546s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.315s]
Building query seed array...  [2.481s]
Computing hash join...  [5.02s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [42.07s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.287s]
Building query seed array...  [1.973s]
Computing hash join...  [5.137s]
Masking low complexity seeds...  [0.249s]
Searching alignments...  [37.351s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.825s]
Building query seed array...  [1.837s]
Computing hash join...  [4.898s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [38.582s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.504s]
Building query seed array...  [2.126s]
Computing hash join...  [4.957s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [29.791s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.172s]
Building query seed array...  [2.218s]
Computing hash join...  [4.962s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [32.032s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.131s]
Building query seed array...  [1.793s]
Computing hash join...  [4.868s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [27.404s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.135s]
Clearing query masking...  [1.521s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [11.556s]
Sorting trace points...  [2.123s]
Computing alignments...  [56.025s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.163s]
Sorting trace points...  [2.009s]
Computing alignments...  [56.696s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.128s]
Sorting trace points...  [1.936s]
Computing alignments...  [55.441s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.834s]
Computing alignments...  [56.354s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0s]
Sorting trace points...  [1.04s]
Computing alignments...  [28.922s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.087s]
Sorting trace points...  [1.173s]
Computing alignments...  [30.065s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0s]
Sorting trace points...  [0.914s]
Computing alignments...  [30.017s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.063s]
Computing alignments...  [30.111s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.174s]
Computing alignments...  [30.338s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.203s]
Computing alignments...  [30.281s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.052s]
Sorting trace points...  [0.94s]
Computing alignments...  [30.282s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.124s]
Computing alignments...  [29.905s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [493.576s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.666s]
Masking reference...  [30.9s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [33.609s]
Allocating buffers...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.409s]
Building query seed array...  [1.996s]
Computing hash join...  [5.142s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [71.356s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.597s]
Building query seed array...  [2.29s]
Computing hash join...  [5.177s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [46.523s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.395s]
Building query seed array...  [2.498s]
Computing hash join...  [5.044s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [40.901s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.902s]
Building query seed array...  [1.992s]
Computing hash join...  [5.001s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [35.089s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.786s]
Building query seed array...  [1.807s]
Computing hash join...  [4.97s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [39.009s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.08s]
Building query seed array...  [2.136s]
Computing hash join...  [4.815s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [29.361s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.682s]
Building query seed array...  [2.318s]
Computing hash join...  [4.882s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [32.369s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.275s]
Building query seed array...  [1.838s]
Computing hash join...  [4.917s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [27.7s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.13s]
Clearing query masking...  [1.566s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [11.367s]
Sorting trace points...  [2.218s]
Computing alignments...  [55.81s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.159s]
Sorting trace points...  [2.167s]
Computing alignments...  [55.963s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.142s]
Sorting trace points...  [1.572s]
Computing alignments...  [55.303s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.794s]
Computing alignments...  [55.333s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
Sorting trace points...  [1.032s]
Computing alignments...  [28.876s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.147s]
Computing alignments...  [30.128s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.001s]
Sorting trace points...  [0.937s]
Computing alignments...  [29.961s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.16s]
Computing alignments...  [30.126s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.037s]
Sorting trace points...  [1.153s]
Computing alignments...  [30.359s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.055s]
Sorting trace points...  [0.891s]
Computing alignments...  [30.268s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.046s]
Computing alignments...  [30.2s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.124s]
Computing alignments...  [30.031s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [490.998s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [29.739s]
Masking reference...  [32.137s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.943s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.057s]
Building query seed array...  [2.06s]
Computing hash join...  [5.179s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [69.78s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.363s]
Building query seed array...  [2.395s]
Computing hash join...  [5.205s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [44.619s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.487s]
Building query seed array...  [2.528s]
Computing hash join...  [5.124s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [39.24s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.177s]
Building query seed array...  [1.997s]
Computing hash join...  [5.095s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [34.562s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.645s]
Building query seed array...  [1.836s]
Computing hash join...  [4.899s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [36.765s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.963s]
Building query seed array...  [2.17s]
Computing hash join...  [4.865s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [30.315s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.486s]
Building query seed array...  [2.227s]
Computing hash join...  [4.899s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [31.733s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.717s]
Building query seed array...  [1.85s]
Computing hash join...  [4.913s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [27.045s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.471s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [11.688s]
Sorting trace points...  [2.239s]
Computing alignments...  [55.879s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.109s]
Sorting trace points...  [2.161s]
Computing alignments...  [56.129s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.12s]
Sorting trace points...  [2.104s]
Computing alignments...  [55.139s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.057s]
Sorting trace points...  [2.115s]
Computing alignments...  [54.896s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.086s]
Sorting trace points...  [0.926s]
Computing alignments...  [28.825s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.077s]
Sorting trace points...  [0.896s]
Computing alignments...  [29.938s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.375s]
Sorting trace points...  [1.157s]
Computing alignments...  [29.859s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.156s]
Computing alignments...  [30.04s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.091s]
Computing alignments...  [30.309s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.082s]
Sorting trace points...  [0.862s]
Computing alignments...  [30.675s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.112s]
Computing alignments...  [30.151s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.164s]
Computing alignments...  [29.784s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [491.659s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.436s]
Masking reference...  [32.175s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.557s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [9.819s]
Building query seed array...  [2.005s]
Computing hash join...  [5.195s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [69.886s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.884s]
Building query seed array...  [2.322s]
Computing hash join...  [5.137s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [44.913s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.331s]
Building query seed array...  [2.431s]
Computing hash join...  [5.025s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [41.772s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.983s]
Building query seed array...  [2.023s]
Computing hash join...  [5.148s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [36.288s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.954s]
Building query seed array...  [1.838s]
Computing hash join...  [5.089s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [38.223s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.993s]
Building query seed array...  [2.133s]
Computing hash join...  [4.845s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [29.096s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.582s]
Building query seed array...  [2.351s]
Computing hash join...  [4.915s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [32.239s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.957s]
Building query seed array...  [1.803s]
Computing hash join...  [4.868s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [27.769s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.595s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [11.49s]
Sorting trace points...  [2.258s]
Computing alignments...  [56.117s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.144s]
Sorting trace points...  [2.213s]
Computing alignments...  [56.401s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.131s]
Sorting trace points...  [2.104s]
Computing alignments...  [55.366s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.044s]
Sorting trace points...  [2.131s]
Computing alignments...  [55.292s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.069s]
Computing alignments...  [28.941s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.092s]
Sorting trace points...  [1.156s]
Computing alignments...  [30.171s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.044s]
Sorting trace points...  [0.86s]
Computing alignments...  [30.139s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.099s]
Computing alignments...  [30.175s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.13s]
Computing alignments...  [30.417s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.044s]
Sorting trace points...  [0.958s]
Computing alignments...  [30.347s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.177s]
Computing alignments...  [30.286s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.135s]
Computing alignments...  [30.02s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
 [493.551s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [32.693s]
Masking reference...  [32.011s]
Initializing dictionary...  [0.08s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [33.665s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.297s]
Building query seed array...  [2.005s]
Computing hash join...  [5.109s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [70.281s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.096s]
Building query seed array...  [2.329s]
Computing hash join...  [5.157s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [44.266s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.409s]
Building query seed array...  [2.424s]
Computing hash join...  [5.093s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [40.103s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.324s]
Building query seed array...  [2s]
Computing hash join...  [5.097s]
Masking low complexity seeds...  [0.249s]
Searching alignments...  [35.92s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.393s]
Building query seed array...  [1.843s]
Computing hash join...  [4.972s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [39.226s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.188s]
Building query seed array...  [2.126s]
Computing hash join...  [4.921s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [29.419s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.053s]
Building query seed array...  [2.216s]
Computing hash join...  [4.957s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [33.718s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.161s]
Building query seed array...  [1.816s]
Computing hash join...  [4.942s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [27.485s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.566s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [11.507s]
Sorting trace points...  [2.174s]
Computing alignments...  [56.146s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.135s]
Sorting trace points...  [2.18s]
Computing alignments...  [56.051s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.145s]
Sorting trace points...  [2.088s]
Computing alignments...  [55.203s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.741s]
Computing alignments...  [55.221s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.077s]
Sorting trace points...  [0.829s]
Computing alignments...  [28.846s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.117s]
Computing alignments...  [30.055s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.062s]
Sorting trace points...  [0.905s]
Computing alignments...  [29.988s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.141s]
Computing alignments...  [30.133s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.084s]
Computing alignments...  [30.46s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.129s]
Computing alignments...  [30.271s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.129s]
Computing alignments...  [30.29s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.114s]
Computing alignments...  [30.031s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [491.934s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [25.021s]
Masking reference...  [25.966s]
Initializing dictionary...  [0.063s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [26.621s]
Allocating buffers...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.185s]
Building query seed array...  [2.01s]
Computing hash join...  [4.307s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [56.085s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [10.136s]
Building query seed array...  [2.337s]
Computing hash join...  [4.325s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [35.124s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [10.95s]
Building query seed array...  [2.549s]
Computing hash join...  [4.429s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [32.564s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [8.394s]
Building query seed array...  [2.019s]
Computing hash join...  [4.34s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [29.034s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [8.33s]
Building query seed array...  [1.824s]
Computing hash join...  [4.102s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [31.879s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [9.887s]
Building query seed array...  [2.141s]
Computing hash join...  [4.048s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [24.285s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [10.876s]
Building query seed array...  [2.23s]
Computing hash join...  [4.115s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [26.249s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [7.955s]
Building query seed array...  [1.808s]
Computing hash join...  [4.113s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [22.682s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.104s]
Clearing query masking...  [1.553s]
Opening temporary output file...  [0.029s]
Computing alignments... Loading trace points...  [9.505s]
Sorting trace points...  [1.812s]
Computing alignments...  [44.934s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.142s]
Sorting trace points...  [1.396s]
Computing alignments...  [44.865s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.106s]
Sorting trace points...  [1.796s]
Computing alignments...  [44.177s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.166s]
Sorting trace points...  [1.742s]
Computing alignments...  [44.319s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.109s]
Sorting trace points...  [1.916s]
Computing alignments...  [46.991s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.137s]
Sorting trace points...  [1.642s]
Computing alignments...  [47.812s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.164s]
Sorting trace points...  [1.538s]
Computing alignments...  [48.407s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
Sorting trace points...  [1.467s]
Computing alignments...  [47.702s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
 [393.117s]
Deallocating reference...  [0.049s]
Loading reference sequences...  [0.103s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [1772.19s]
 [1772.19s]
Deallocating queries...  [0.048s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [3.61s]
 [4.59s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 16547.5s
Reported 2230529217 pairwise alignments, 2230529217 HSPs.
13007564 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C28_R2.fastp-trim.20230215.fq.gz complete: C28_R2.blastx.meganized.daa

Now MEGANizing C28_R2.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: C28_R2.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 100% (260.0s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (2.4s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (4,178.4s)
Total reads:       13,007,564
With hits:          13,007,564 
Alignments:      2,227,120,155
Assig. Taxonomy:    12,258,631
Assig. SEED:            87,127
Assig. EGGNOG:          44,158
Assig. GTDB:           350,833
Assig. EC:           2,096,453
Assig. INTERPRO2GO:  1,041,256
MinSupport set to: 6503
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.5s)
Min-supp. changes:       3,720
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (10.7s)
Min-supp. changes:       2,818
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (29.3s)
Binning reads Syncing
100% (0.4s)
Class. Taxonomy:            60
Class. SEED:               470
Class. EGGNOG:           1,734
Class. GTDB:                18
Class. EC:               2,293
Class. INTERPRO2GO:      7,576
Total time:  4,490s
Peak memory: 31.6 of 195.3G
MEGANization of C28_R2.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C29_R1.fastp-trim.20230215.fq.gz...
4f0f98b18c86aa0085ee0f595645bc51  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C29_R1.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C29_R1.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.338s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.793s]
Opening the output file...  [0s]
Loading query sequences...  [55.481s]
Masking queries...  [13.96s]
Algorithm: Double-indexed
Building query histograms...  [13.805s]
Loading reference sequences...  [29.413s]
Masking reference...  [32.05s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.199s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.338s]
Building query seed array...  [1.62s]
Computing hash join...  [5.057s]
Masking low complexity seeds...  [0.194s]
Searching alignments...  [55.072s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.439s]
Building query seed array...  [1.75s]
Computing hash join...  [4.859s]
Masking low complexity seeds...  [0.193s]
Searching alignments...  [35.185s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [12.869s]
Building query seed array...  [1.861s]
Computing hash join...  [4.792s]
Masking low complexity seeds...  [0.195s]
Searching alignments...  [31.451s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.924s]
Building query seed array...  [1.586s]
Computing hash join...  [4.823s]
Masking low complexity seeds...  [0.195s]
Searching alignments...  [26.594s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.063s]
Building query seed array...  [1.42s]
Computing hash join...  [4.705s]
Masking low complexity seeds...  [0.183s]
Searching alignments...  [27.587s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.648s]
Building query seed array...  [1.585s]
Computing hash join...  [4.649s]
Masking low complexity seeds...  [0.182s]
Searching alignments...  [21.583s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [14.149s]
Building query seed array...  [1.732s]
Computing hash join...  [4.664s]
Masking low complexity seeds...  [0.179s]
Searching alignments...  [24.755s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.766s]
Building query seed array...  [1.38s]
Computing hash join...  [4.756s]
Masking low complexity seeds...  [0.179s]
Searching alignments...  [21.053s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.243s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [9.172s]
Sorting trace points...  [1.693s]
Computing alignments...  [57.642s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.16s]
Sorting trace points...  [1.642s]
Computing alignments...  [43.375s]
Deallocating buffers...  [0.023s]
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Sorting trace points...  [1.615s]
Computing alignments...  [43.242s]
Deallocating buffers...  [0.026s]
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Sorting trace points...  [1.339s]
Computing alignments...  [42.926s]
Deallocating buffers...  [0.021s]
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Sorting trace points...  [1.488s]
Computing alignments...  [44.85s]
Deallocating buffers...  [0.028s]
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Sorting trace points...  [1.75s]
Computing alignments...  [45.251s]
Deallocating buffers...  [0.032s]
Loading trace points...  [0.146s]
Sorting trace points...  [1.696s]
Computing alignments...  [45.322s]
Deallocating buffers...  [0.023s]
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Sorting trace points...  [1.692s]
Computing alignments...  [45.648s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
 [392.275s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [33.014s]
Masking reference...  [31.506s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.138s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.274s]
Building query seed array...  [1.626s]
Computing hash join...  [4.892s]
Masking low complexity seeds...  [0.192s]
Searching alignments...  [52.163s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.473s]
Building query seed array...  [1.83s]
Computing hash join...  [4.927s]
Masking low complexity seeds...  [0.19s]
Searching alignments...  [35.057s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.244s]
Building query seed array...  [1.936s]
Computing hash join...  [4.873s]
Masking low complexity seeds...  [0.199s]
Searching alignments...  [29.41s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.171s]
Building query seed array...  [1.516s]
Computing hash join...  [4.778s]
Masking low complexity seeds...  [0.186s]
Searching alignments...  [26.472s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.164s]
Building query seed array...  [1.419s]
Computing hash join...  [4.741s]
Masking low complexity seeds...  [0.182s]
Searching alignments...  [27.328s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.088s]
Building query seed array...  [1.653s]
Computing hash join...  [4.663s]
Masking low complexity seeds...  [0.175s]
Searching alignments...  [22.343s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.378s]
Building query seed array...  [1.687s]
Computing hash join...  [4.704s]
Masking low complexity seeds...  [0.186s]
Searching alignments...  [23.223s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.998s]
Building query seed array...  [1.456s]
Computing hash join...  [4.666s]
Masking low complexity seeds...  [0.191s]
Searching alignments...  [20.653s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.116s]
Clearing query masking...  [1.213s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [9.109s]
Sorting trace points...  [1.717s]
Computing alignments...  [56.786s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.136s]
Sorting trace points...  [1.328s]
Computing alignments...  [43.656s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.142s]
Sorting trace points...  [1.268s]
Computing alignments...  [43.171s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0.104s]
Sorting trace points...  [1.36s]
Computing alignments...  [42.978s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0.146s]
Sorting trace points...  [1.376s]
Computing alignments...  [44.695s]
Deallocating buffers...  [0.022s]
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Sorting trace points...  [1.71s]
Computing alignments...  [45.071s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.102s]
Sorting trace points...  [1.415s]
Computing alignments...  [44.926s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
Sorting trace points...  [1.659s]
Computing alignments...  [45.027s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0s]
 [388.342s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.502s]
Masking reference...  [30.931s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.911s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.417s]
Building query seed array...  [1.557s]
Computing hash join...  [4.938s]
Masking low complexity seeds...  [0.192s]
Searching alignments...  [55.523s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.658s]
Building query seed array...  [1.793s]
Computing hash join...  [4.837s]
Masking low complexity seeds...  [0.186s]
Searching alignments...  [35.257s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.371s]
Building query seed array...  [1.868s]
Computing hash join...  [4.819s]
Masking low complexity seeds...  [0.185s]
Searching alignments...  [31.774s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.372s]
Building query seed array...  [1.512s]
Computing hash join...  [4.828s]
Masking low complexity seeds...  [0.197s]
Searching alignments...  [27.625s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.797s]
Building query seed array...  [1.404s]
Computing hash join...  [4.682s]
Masking low complexity seeds...  [0.186s]
Searching alignments...  [27.485s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.292s]
Building query seed array...  [1.595s]
Computing hash join...  [4.698s]
Masking low complexity seeds...  [0.173s]
Searching alignments...  [22.013s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.892s]
Building query seed array...  [1.682s]
Computing hash join...  [4.728s]
Masking low complexity seeds...  [0.189s]
Searching alignments...  [23.948s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.934s]
Building query seed array...  [1.348s]
Computing hash join...  [4.686s]
Masking low complexity seeds...  [0.189s]
Searching alignments...  [21.341s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.136s]
Clearing query masking...  [1.255s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [9.668s]
Sorting trace points...  [1.696s]
Computing alignments...  [55.364s]
Deallocating buffers...  [0.042s]
Loading trace points...  [0.144s]
Sorting trace points...  [1.737s]
Computing alignments...  [43.498s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.133s]
Sorting trace points...  [1.543s]
Computing alignments...  [43.278s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0.107s]
Sorting trace points...  [1.615s]
Computing alignments...  [42.815s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.675s]
Computing alignments...  [44.82s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.097s]
Sorting trace points...  [1.673s]
Computing alignments...  [45.167s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.096s]
Sorting trace points...  [1.35s]
Computing alignments...  [45.113s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0s]
Sorting trace points...  [1.447s]
Computing alignments...  [45.219s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0s]
 [388.733s]
Deallocating reference...  [0.065s]
Loading reference sequences...  [29.792s]
Masking reference...  [30.929s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.743s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.014s]
Building query seed array...  [1.525s]
Computing hash join...  [4.873s]
Masking low complexity seeds...  [0.189s]
Searching alignments...  [52.824s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.333s]
Building query seed array...  [1.819s]
Computing hash join...  [4.931s]
Masking low complexity seeds...  [0.197s]
Searching alignments...  [34.039s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.875s]
Building query seed array...  [1.864s]
Computing hash join...  [4.899s]
Masking low complexity seeds...  [0.196s]
Searching alignments...  [29.547s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.976s]
Building query seed array...  [1.565s]
Computing hash join...  [4.844s]
Masking low complexity seeds...  [0.188s]
Searching alignments...  [26.814s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.297s]
Building query seed array...  [1.38s]
Computing hash join...  [4.799s]
Masking low complexity seeds...  [0.187s]
Searching alignments...  [27.823s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.302s]
Building query seed array...  [1.61s]
Computing hash join...  [4.59s]
Masking low complexity seeds...  [0.184s]
Searching alignments...  [21.585s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.619s]
Building query seed array...  [1.736s]
Computing hash join...  [4.748s]
Masking low complexity seeds...  [0.189s]
Searching alignments...  [23.698s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.476s]
Building query seed array...  [1.395s]
Computing hash join...  [4.744s]
Masking low complexity seeds...  [0.183s]
Searching alignments...  [20.874s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.216s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [8.977s]
Sorting trace points...  [1.662s]
Computing alignments...  [56.889s]
Deallocating buffers...  [0.039s]
Loading trace points...  [0.153s]
Sorting trace points...  [1.658s]
Computing alignments...  [43.251s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.164s]
Sorting trace points...  [1.619s]
Computing alignments...  [42.983s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.187s]
Sorting trace points...  [1.308s]
Computing alignments...  [42.742s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.276s]
Computing alignments...  [44.708s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.389s]
Computing alignments...  [45.018s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.121s]
Sorting trace points...  [1.705s]
Computing alignments...  [45.006s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.619s]
Computing alignments...  [45.034s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0s]
 [387.917s]
Deallocating reference...  [0.065s]
Loading reference sequences...  [31.706s]
Masking reference...  [31.743s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.344s]
Allocating buffers...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.669s]
Building query seed array...  [1.507s]
Computing hash join...  [4.917s]
Masking low complexity seeds...  [0.197s]
Searching alignments...  [54.761s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.384s]
Building query seed array...  [1.822s]
Computing hash join...  [4.779s]
Masking low complexity seeds...  [0.691s]
Searching alignments...  [35.043s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.429s]
Building query seed array...  [1.87s]
Computing hash join...  [4.773s]
Masking low complexity seeds...  [0.195s]
Searching alignments...  [31.056s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.157s]
Building query seed array...  [1.584s]
Computing hash join...  [4.83s]
Masking low complexity seeds...  [0.2s]
Searching alignments...  [26.972s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.907s]
Building query seed array...  [1.369s]
Computing hash join...  [4.743s]
Masking low complexity seeds...  [0.185s]
Searching alignments...  [27.563s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.387s]
Building query seed array...  [1.589s]
Computing hash join...  [4.678s]
Masking low complexity seeds...  [0.176s]
Searching alignments...  [21.521s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.458s]
Building query seed array...  [1.678s]
Computing hash join...  [4.738s]
Masking low complexity seeds...  [0.18s]
Searching alignments...  [24.002s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.819s]
Building query seed array...  [1.419s]
Computing hash join...  [4.627s]
Masking low complexity seeds...  [0.182s]
Searching alignments...  [20.631s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.198s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [9.661s]
Sorting trace points...  [1.327s]
Computing alignments...  [57.577s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.115s]
Sorting trace points...  [1.384s]
Computing alignments...  [43.095s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.147s]
Sorting trace points...  [1.627s]
Computing alignments...  [42.883s]
Deallocating buffers...  [0.034s]
Loading trace points...  [0.104s]
Sorting trace points...  [1.323s]
Computing alignments...  [42.501s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.609s]
Computing alignments...  [44.548s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.698s]
Computing alignments...  [44.816s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.139s]
Sorting trace points...  [1.676s]
Computing alignments...  [44.839s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [1.322s]
Computing alignments...  [44.697s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
 [387.558s]
Deallocating reference...  [0.068s]
Loading reference sequences...  [29.645s]
Masking reference...  [32.156s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.548s]
Allocating buffers...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.325s]
Building query seed array...  [1.517s]
Computing hash join...  [4.934s]
Masking low complexity seeds...  [0.192s]
Searching alignments...  [50.575s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.258s]
Building query seed array...  [1.82s]
Computing hash join...  [4.823s]
Masking low complexity seeds...  [0.199s]
Searching alignments...  [33.648s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.16s]
Building query seed array...  [1.87s]
Computing hash join...  [4.803s]
Masking low complexity seeds...  [0.194s]
Searching alignments...  [29.368s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.029s]
Building query seed array...  [1.501s]
Computing hash join...  [4.799s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [25.533s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.82s]
Building query seed array...  [1.366s]
Computing hash join...  [4.654s]
Masking low complexity seeds...  [0.183s]
Searching alignments...  [28.224s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.6s]
Building query seed array...  [1.654s]
Computing hash join...  [4.674s]
Masking low complexity seeds...  [0.18s]
Searching alignments...  [21.737s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.078s]
Building query seed array...  [1.693s]
Computing hash join...  [4.723s]
Masking low complexity seeds...  [0.18s]
Searching alignments...  [23.202s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.786s]
Building query seed array...  [1.42s]
Computing hash join...  [4.715s]
Masking low complexity seeds...  [0.182s]
Searching alignments...  [20.698s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.12s]
Clearing query masking...  [1.207s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [8.958s]
Sorting trace points...  [1.672s]
Computing alignments...  [57.645s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.12s]
Sorting trace points...  [1.363s]
Computing alignments...  [42.795s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.111s]
Sorting trace points...  [1.598s]
Computing alignments...  [42.765s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.58s]
Computing alignments...  [42.53s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.153s]
Sorting trace points...  [1.674s]
Computing alignments...  [44.305s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.442s]
Computing alignments...  [44.748s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.114s]
Sorting trace points...  [1.714s]
Computing alignments...  [44.611s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.275s]
Computing alignments...  [44.676s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
 [386.343s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.552s]
Masking reference...  [32.102s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.011s]
Building reference histograms...  [32.187s]
Allocating buffers...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.254s]
Building query seed array...  [1.574s]
Computing hash join...  [4.802s]
Masking low complexity seeds...  [0.189s]
Searching alignments...  [55.813s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.323s]
Building query seed array...  [1.772s]
Computing hash join...  [4.859s]
Masking low complexity seeds...  [0.192s]
Searching alignments...  [33.679s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.006s]
Building query seed array...  [1.843s]
Computing hash join...  [4.904s]
Masking low complexity seeds...  [0.196s]
Searching alignments...  [30.785s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.143s]
Building query seed array...  [1.586s]
Computing hash join...  [4.77s]
Masking low complexity seeds...  [0.189s]
Searching alignments...  [26.911s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.975s]
Building query seed array...  [1.401s]
Computing hash join...  [4.661s]
Masking low complexity seeds...  [0.185s]
Searching alignments...  [27.704s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.28s]
Building query seed array...  [1.607s]
Computing hash join...  [4.647s]
Masking low complexity seeds...  [0.182s]
Searching alignments...  [21.933s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.498s]
Building query seed array...  [1.768s]
Computing hash join...  [4.626s]
Masking low complexity seeds...  [0.178s]
Searching alignments...  [25.057s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.885s]
Building query seed array...  [1.398s]
Computing hash join...  [4.755s]
Masking low complexity seeds...  [0.179s]
Searching alignments...  [21.343s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.127s]
Clearing query masking...  [1.222s]
Opening temporary output file...  [0.002s]
Computing alignments... Loading trace points...  [8.934s]
Sorting trace points...  [1.597s]
Computing alignments...  [55.056s]
Deallocating buffers...  [0.036s]
Loading trace points...  [0.129s]
Sorting trace points...  [1.681s]
Computing alignments...  [43.167s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.13s]
Sorting trace points...  [1.672s]
Computing alignments...  [43.016s]
Deallocating buffers...  [0.036s]
Loading trace points...  [0.181s]
Sorting trace points...  [1.512s]
Computing alignments...  [42.722s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.105s]
Sorting trace points...  [1.673s]
Computing alignments...  [44.637s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.103s]
Sorting trace points...  [1.728s]
Computing alignments...  [45.037s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.114s]
Sorting trace points...  [1.308s]
Computing alignments...  [44.998s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
Sorting trace points...  [1.376s]
Computing alignments...  [45.023s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0s]
 [386.298s]
Deallocating reference...  [0.07s]
Loading reference sequences...  [31.517s]
Masking reference...  [30.939s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.655s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.442s]
Building query seed array...  [1.544s]
Computing hash join...  [4.798s]
Masking low complexity seeds...  [0.187s]
Searching alignments...  [52.825s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.223s]
Building query seed array...  [1.755s]
Computing hash join...  [4.829s]
Masking low complexity seeds...  [0.187s]
Searching alignments...  [33.279s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [12.842s]
Building query seed array...  [1.87s]
Computing hash join...  [4.836s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [29.416s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.838s]
Building query seed array...  [1.56s]
Computing hash join...  [4.885s]
Masking low complexity seeds...  [0.196s]
Searching alignments...  [28.837s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.963s]
Building query seed array...  [1.391s]
Computing hash join...  [4.766s]
Masking low complexity seeds...  [0.18s]
Searching alignments...  [28.799s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.909s]
Building query seed array...  [1.645s]
Computing hash join...  [4.7s]
Masking low complexity seeds...  [0.18s]
Searching alignments...  [21.694s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.418s]
Building query seed array...  [1.695s]
Computing hash join...  [4.737s]
Masking low complexity seeds...  [0.185s]
Searching alignments...  [23.918s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.032s]
Building query seed array...  [1.411s]
Computing hash join...  [4.695s]
Masking low complexity seeds...  [0.187s]
Searching alignments...  [21.281s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.247s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [9.164s]
Sorting trace points...  [1.748s]
Computing alignments...  [55.512s]
Deallocating buffers...  [0.036s]
Loading trace points...  [0.139s]
Sorting trace points...  [1.352s]
Computing alignments...  [43.231s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.151s]
Sorting trace points...  [1.614s]
Computing alignments...  [43.103s]
Deallocating buffers...  [0.036s]
Loading trace points...  [0.142s]
Sorting trace points...  [1.503s]
Computing alignments...  [42.726s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.105s]
Sorting trace points...  [1.74s]
Computing alignments...  [44.672s]
Deallocating buffers...  [0.035s]
Loading trace points...  [0.102s]
Sorting trace points...  [1.704s]
Computing alignments...  [45.535s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.132s]
Sorting trace points...  [1.483s]
Computing alignments...  [44.941s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
Sorting trace points...  [1.695s]
Computing alignments...  [44.935s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [387.817s]
Deallocating reference...  [0.065s]
Loading reference sequences...  [32.474s]
Masking reference...  [32.198s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.545s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [9.798s]
Building query seed array...  [1.66s]
Computing hash join...  [4.913s]
Masking low complexity seeds...  [0.191s]
Searching alignments...  [53.095s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [11.967s]
Building query seed array...  [1.822s]
Computing hash join...  [4.841s]
Masking low complexity seeds...  [0.192s]
Searching alignments...  [34.741s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.126s]
Building query seed array...  [1.879s]
Computing hash join...  [4.855s]
Masking low complexity seeds...  [0.191s]
Searching alignments...  [30.576s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.588s]
Building query seed array...  [1.511s]
Computing hash join...  [4.912s]
Masking low complexity seeds...  [0.191s]
Searching alignments...  [26.423s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.939s]
Building query seed array...  [1.418s]
Computing hash join...  [4.707s]
Masking low complexity seeds...  [0.181s]
Searching alignments...  [26.965s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.1s]
Building query seed array...  [1.652s]
Computing hash join...  [4.616s]
Masking low complexity seeds...  [0.178s]
Searching alignments...  [22.073s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.834s]
Building query seed array...  [1.704s]
Computing hash join...  [4.745s]
Masking low complexity seeds...  [0.174s]
Searching alignments...  [24.091s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.782s]
Building query seed array...  [1.415s]
Computing hash join...  [4.604s]
Masking low complexity seeds...  [0.179s]
Searching alignments...  [20.75s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.191s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [9.047s]
Sorting trace points...  [1.646s]
Computing alignments...  [55.48s]
Deallocating buffers...  [0.038s]
Loading trace points...  [0.126s]
Sorting trace points...  [1.361s]
Computing alignments...  [43.084s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.149s]
Sorting trace points...  [1.477s]
Computing alignments...  [42.871s]
Deallocating buffers...  [0.032s]
Loading trace points...  [0.125s]
Sorting trace points...  [1.624s]
Computing alignments...  [42.684s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.888s]
Sorting trace points...  [1.643s]
Computing alignments...  [44.599s]
Deallocating buffers...  [0.036s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.522s]
Computing alignments...  [44.976s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.141s]
Sorting trace points...  [1.691s]
Computing alignments...  [44.973s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0s]
Sorting trace points...  [1.384s]
Computing alignments...  [44.986s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
 [386.922s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [29.54s]
Masking reference...  [30.841s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.032s]
Allocating buffers...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.338s]
Building query seed array...  [1.603s]
Computing hash join...  [4.886s]
Masking low complexity seeds...  [0.193s]
Searching alignments...  [53.628s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.182s]
Building query seed array...  [1.812s]
Computing hash join...  [4.873s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [33.591s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.945s]
Building query seed array...  [1.887s]
Computing hash join...  [4.906s]
Masking low complexity seeds...  [0.191s]
Searching alignments...  [29.892s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.294s]
Building query seed array...  [1.529s]
Computing hash join...  [4.795s]
Masking low complexity seeds...  [0.184s]
Searching alignments...  [28.013s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.301s]
Building query seed array...  [1.39s]
Computing hash join...  [4.653s]
Masking low complexity seeds...  [0.178s]
Searching alignments...  [27.792s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.486s]
Building query seed array...  [1.603s]
Computing hash join...  [4.638s]
Masking low complexity seeds...  [0.177s]
Searching alignments...  [21.604s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.55s]
Building query seed array...  [1.669s]
Computing hash join...  [4.693s]
Masking low complexity seeds...  [0.18s]
Searching alignments...  [23.941s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.158s]
Building query seed array...  [1.393s]
Computing hash join...  [4.619s]
Masking low complexity seeds...  [0.193s]
Searching alignments...  [22.603s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.121s]
Clearing query masking...  [1.272s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [9.116s]
Sorting trace points...  [1.705s]
Computing alignments...  [55.177s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0.14s]
Sorting trace points...  [1.637s]
Computing alignments...  [43.198s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.732s]
Sorting trace points...  [1.662s]
Computing alignments...  [43.045s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.096s]
Sorting trace points...  [1.645s]
Computing alignments...  [42.681s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.263s]
Computing alignments...  [44.686s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.658s]
Computing alignments...  [44.895s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.141s]
Sorting trace points...  [1.395s]
Computing alignments...  [44.938s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0s]
Sorting trace points...  [1.721s]
Computing alignments...  [44.849s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [386.851s]
Deallocating reference...  [0.07s]
Loading reference sequences...  [33.818s]
Masking reference...  [31.28s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.011s]
Building reference histograms...  [33.013s]
Allocating buffers...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.356s]
Building query seed array...  [1.533s]
Computing hash join...  [4.861s]
Masking low complexity seeds...  [0.194s]
Searching alignments...  [55.561s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.689s]
Building query seed array...  [1.776s]
Computing hash join...  [4.918s]
Masking low complexity seeds...  [0.193s]
Searching alignments...  [34.132s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.072s]
Building query seed array...  [1.867s]
Computing hash join...  [4.968s]
Masking low complexity seeds...  [0.197s]
Searching alignments...  [30.474s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.085s]
Building query seed array...  [1.484s]
Computing hash join...  [4.874s]
Masking low complexity seeds...  [0.192s]
Searching alignments...  [26.081s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.811s]
Building query seed array...  [1.374s]
Computing hash join...  [4.677s]
Masking low complexity seeds...  [0.181s]
Searching alignments...  [26.964s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.573s]
Building query seed array...  [1.656s]
Computing hash join...  [4.727s]
Masking low complexity seeds...  [0.188s]
Searching alignments...  [22.644s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.587s]
Building query seed array...  [1.671s]
Computing hash join...  [4.748s]
Masking low complexity seeds...  [0.182s]
Searching alignments...  [23.996s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.008s]
Building query seed array...  [1.423s]
Computing hash join...  [4.791s]
Masking low complexity seeds...  [0.191s]
Searching alignments...  [20.279s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.117s]
Clearing query masking...  [1.293s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [9.887s]
Sorting trace points...  [1.631s]
Computing alignments...  [54.619s]
Deallocating buffers...  [0.032s]
Loading trace points...  [0.108s]
Sorting trace points...  [1.634s]
Computing alignments...  [43.08s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.126s]
Sorting trace points...  [1.483s]
Computing alignments...  [42.997s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.575s]
Computing alignments...  [42.625s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.143s]
Sorting trace points...  [1.577s]
Computing alignments...  [44.589s]
Deallocating buffers...  [0.034s]
Loading trace points...  [0.157s]
Sorting trace points...  [1.663s]
Computing alignments...  [44.846s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.448s]
Computing alignments...  [44.73s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
Sorting trace points...  [1.694s]
Computing alignments...  [44.811s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0s]
 [385.89s]
Deallocating reference...  [0.065s]
Loading reference sequences...  [29.748s]
Masking reference...  [32.138s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.631s]
Allocating buffers...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [9.974s]
Building query seed array...  [1.565s]
Computing hash join...  [4.909s]
Masking low complexity seeds...  [0.199s]
Searching alignments...  [53.214s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.854s]
Building query seed array...  [1.747s]
Computing hash join...  [4.794s]
Masking low complexity seeds...  [0.196s]
Searching alignments...  [33.28s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.134s]
Building query seed array...  [1.92s]
Computing hash join...  [4.831s]
Masking low complexity seeds...  [0.191s]
Searching alignments...  [29.399s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.311s]
Building query seed array...  [1.527s]
Computing hash join...  [4.785s]
Masking low complexity seeds...  [0.184s]
Searching alignments...  [26.688s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.945s]
Building query seed array...  [1.395s]
Computing hash join...  [4.73s]
Masking low complexity seeds...  [0.178s]
Searching alignments...  [27.365s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.152s]
Building query seed array...  [1.597s]
Computing hash join...  [4.686s]
Masking low complexity seeds...  [0.181s]
Searching alignments...  [21.426s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.161s]
Building query seed array...  [1.682s]
Computing hash join...  [4.727s]
Masking low complexity seeds...  [0.183s]
Searching alignments...  [23.765s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.861s]
Building query seed array...  [1.404s]
Computing hash join...  [4.737s]
Masking low complexity seeds...  [0.187s]
Searching alignments...  [21.325s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.132s]
Clearing query masking...  [1.233s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [9.681s]
Sorting trace points...  [1.663s]
Computing alignments...  [58.03s]
Deallocating buffers...  [0.032s]
Loading trace points...  [0.185s]
Sorting trace points...  [1.622s]
Computing alignments...  [43.218s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.193s]
Sorting trace points...  [1.295s]
Computing alignments...  [43.119s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.105s]
Sorting trace points...  [1.342s]
Computing alignments...  [42.742s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.091s]
Sorting trace points...  [1.701s]
Computing alignments...  [44.697s]
Deallocating buffers...  [0.034s]
Loading trace points...  [0.088s]
Sorting trace points...  [1.636s]
Computing alignments...  [45.098s]
Deallocating buffers...  [0.024s]
Loading trace points...  [1.355s]
Sorting trace points...  [1.551s]
Computing alignments...  [44.976s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0s]
Sorting trace points...  [1.294s]
Computing alignments...  [45.068s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
 [391.205s]
Deallocating reference...  [0.064s]
Loading reference sequences...  [30.035s]
Masking reference...  [31.271s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [33.121s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.105s]
Building query seed array...  [1.582s]
Computing hash join...  [4.876s]
Masking low complexity seeds...  [0.186s]
Searching alignments...  [55.17s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.37s]
Building query seed array...  [1.815s]
Computing hash join...  [4.96s]
Masking low complexity seeds...  [0.192s]
Searching alignments...  [34.183s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.156s]
Building query seed array...  [1.88s]
Computing hash join...  [4.903s]
Masking low complexity seeds...  [0.186s]
Searching alignments...  [29.821s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.841s]
Building query seed array...  [1.507s]
Computing hash join...  [4.869s]
Masking low complexity seeds...  [0.191s]
Searching alignments...  [26.884s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.838s]
Building query seed array...  [1.413s]
Computing hash join...  [4.73s]
Masking low complexity seeds...  [0.182s]
Searching alignments...  [27.08s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.167s]
Building query seed array...  [1.637s]
Computing hash join...  [4.648s]
Masking low complexity seeds...  [0.179s]
Searching alignments...  [21.607s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.426s]
Building query seed array...  [1.711s]
Computing hash join...  [4.701s]
Masking low complexity seeds...  [0.183s]
Searching alignments...  [24.125s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.866s]
Building query seed array...  [1.386s]
Computing hash join...  [4.699s]
Masking low complexity seeds...  [0.187s]
Searching alignments...  [21.083s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.118s]
Clearing query masking...  [1.191s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [9.143s]
Sorting trace points...  [1.675s]
Computing alignments...  [56.623s]
Deallocating buffers...  [0.037s]
Loading trace points...  [0.135s]
Sorting trace points...  [1.409s]
Computing alignments...  [43.036s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.185s]
Sorting trace points...  [1.257s]
Computing alignments...  [42.805s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0.113s]
Sorting trace points...  [1.675s]
Computing alignments...  [43.031s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.168s]
Sorting trace points...  [1.432s]
Computing alignments...  [44.49s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.154s]
Sorting trace points...  [1.669s]
Computing alignments...  [44.857s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.098s]
Sorting trace points...  [1.354s]
Computing alignments...  [44.929s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
Sorting trace points...  [1.663s]
Computing alignments...  [44.889s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0s]
 [387.125s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [23.74s]
Masking reference...  [24.992s]
Initializing dictionary...  [0.063s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [26.944s]
Allocating buffers...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [7.936s]
Building query seed array...  [1.524s]
Computing hash join...  [4.037s]
Masking low complexity seeds...  [0.185s]
Searching alignments...  [45.404s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [10.239s]
Building query seed array...  [1.777s]
Computing hash join...  [4.061s]
Masking low complexity seeds...  [0.182s]
Searching alignments...  [27.86s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [10.637s]
Building query seed array...  [1.915s]
Computing hash join...  [3.97s]
Masking low complexity seeds...  [0.179s]
Searching alignments...  [24.05s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [8.245s]
Building query seed array...  [1.565s]
Computing hash join...  [4.018s]
Masking low complexity seeds...  [0.181s]
Searching alignments...  [22.54s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [8.328s]
Building query seed array...  [1.415s]
Computing hash join...  [3.911s]
Masking low complexity seeds...  [0.172s]
Searching alignments...  [21.892s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [9.973s]
Building query seed array...  [1.605s]
Computing hash join...  [3.859s]
Masking low complexity seeds...  [0.176s]
Searching alignments...  [17.703s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [10.868s]
Building query seed array...  [1.698s]
Computing hash join...  [3.876s]
Masking low complexity seeds...  [0.178s]
Searching alignments...  [19.001s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [8.46s]
Building query seed array...  [1.427s]
Computing hash join...  [3.856s]
Masking low complexity seeds...  [0.169s]
Searching alignments...  [16.824s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.101s]
Clearing query masking...  [1.23s]
Opening temporary output file...  [0.002s]
Computing alignments... Loading trace points...  [11.5s]
Sorting trace points...  [2.061s]
Computing alignments...  [53.083s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.199s]
Sorting trace points...  [1.95s]
Computing alignments...  [51.054s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.22s]
Sorting trace points...  [2.023s]
Computing alignments...  [51.581s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.207s]
Sorting trace points...  [1.867s]
Computing alignments...  [54.037s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.08s]
Sorting trace points...  [2.148s]
Computing alignments...  [53.445s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
Sorting trace points...  [0.719s]
Computing alignments...  [17.896s]
Deallocating buffers...  [0.008s]
Loading trace points...  [0s]
 [304.412s]
Deallocating reference...  [0.052s]
Loading reference sequences...  [0.093s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [1362.91s]
 [1362.91s]
Deallocating queries...  [0.04s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [3.971s]
 [5.102s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 13444s
Reported 1745637419 pairwise alignments, 1745637419 HSPs.
9669714 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C29_R1.fastp-trim.20230215.fq.gz complete: C29_R1.blastx.meganized.daa

Now MEGANizing C29_R1.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: C29_R1.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 80% 100% (271.9s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.3s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (3,129.6s)
Total reads:        9,669,714
With hits:           9,669,714 
Alignments:      1,724,320,028
Assig. Taxonomy:     8,953,437
Assig. SEED:            83,117
Assig. EGGNOG:          43,823
Assig. GTDB:           300,644
Assig. EC:           1,486,755
Assig. INTERPRO2GO:    834,784
MinSupport set to: 4834
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.5s)
Min-supp. changes:       3,930
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (6.9s)
Min-supp. changes:       2,943
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (14.0s)
Binning reads Syncing
100% (0.3s)
Class. Taxonomy:            65
Class. SEED:               505
Class. EGGNOG:           1,791
Class. GTDB:                23
Class. EC:               2,339
Class. INTERPRO2GO:      7,488
Total time:  3,432s
Peak memory: 31.4 of 195.3G
MEGANization of C29_R1.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C29_R2.fastp-trim.20230215.fq.gz...
6b0d7d75445b68b0a2c7fc832987d4b9  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C29_R2.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C29_R2.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.469s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.753s]
Opening the output file...  [0s]
Loading query sequences...  [55.395s]
Masking queries...  [13.984s]
Algorithm: Double-indexed
Building query histograms...  [15.086s]
Loading reference sequences...  [31.427s]
Masking reference...  [32.083s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [31.808s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.167s]
Building query seed array...  [1.561s]
Computing hash join...  [5.012s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [52.543s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.487s]
Building query seed array...  [1.815s]
Computing hash join...  [4.897s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [33.746s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.779s]
Building query seed array...  [1.871s]
Computing hash join...  [4.958s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [30.191s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.369s]
Building query seed array...  [1.531s]
Computing hash join...  [4.909s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [27.331s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.921s]
Building query seed array...  [1.394s]
Computing hash join...  [4.751s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [29.899s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.232s]
Building query seed array...  [1.622s]
Computing hash join...  [4.738s]
Masking low complexity seeds...  [0.2s]
Searching alignments...  [22.368s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.888s]
Building query seed array...  [1.775s]
Computing hash join...  [4.796s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [25.694s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.829s]
Building query seed array...  [1.375s]
Computing hash join...  [4.806s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [23.122s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.121s]
Clearing query masking...  [1.246s]
Opening temporary output file...  [0.002s]
Computing alignments... Loading trace points...  [9.296s]
Sorting trace points...  [1.66s]
Computing alignments...  [43.308s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.156s]
Sorting trace points...  [1.49s]
Computing alignments...  [42.37s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.003s]
Sorting trace points...  [1.341s]
Computing alignments...  [47.662s]
Deallocating buffers...  [0.165s]
Loading trace points...  [0.187s]
Sorting trace points...  [1.637s]
Computing alignments...  [42.839s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.615s]
Computing alignments...  [45.284s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.702s]
Computing alignments...  [46.284s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.441s]
Computing alignments...  [46.265s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [1.445s]
Computing alignments...  [45.935s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
 [382.531s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [29.687s]
Masking reference...  [30.908s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [33.269s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.441s]
Building query seed array...  [1.557s]
Computing hash join...  [5.006s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [55.9s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.085s]
Building query seed array...  [1.825s]
Computing hash join...  [4.995s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [33.975s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.595s]
Building query seed array...  [1.855s]
Computing hash join...  [4.941s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [32.294s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.255s]
Building query seed array...  [1.495s]
Computing hash join...  [4.961s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [26.551s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.934s]
Building query seed array...  [1.464s]
Computing hash join...  [4.806s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [28.883s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.6s]
Building query seed array...  [1.661s]
Computing hash join...  [4.7s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [22.108s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.558s]
Building query seed array...  [1.764s]
Computing hash join...  [4.733s]
Masking low complexity seeds...  [0.199s]
Searching alignments...  [24.662s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.898s]
Building query seed array...  [1.377s]
Computing hash join...  [4.766s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [21.104s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.142s]
Clearing query masking...  [1.251s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [9.012s]
Sorting trace points...  [1.576s]
Computing alignments...  [42.956s]
Deallocating buffers...  [0.035s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.64s]
Computing alignments...  [42.197s]
Deallocating buffers...  [0.035s]
Loading trace points...  [0.157s]
Sorting trace points...  [1.298s]
Computing alignments...  [46.199s]
Deallocating buffers...  [0.15s]
Loading trace points...  [0.143s]
Sorting trace points...  [1.613s]
Computing alignments...  [42.436s]
Deallocating buffers...  [0.036s]
Loading trace points...  [0.145s]
Sorting trace points...  [1.38s]
Computing alignments...  [45.153s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.155s]
Sorting trace points...  [1.77s]
Computing alignments...  [46.107s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.158s]
Sorting trace points...  [1.602s]
Computing alignments...  [46.207s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0s]
Sorting trace points...  [1.711s]
Computing alignments...  [46.064s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0s]
 [380.187s]
Deallocating reference...  [0.068s]
Loading reference sequences...  [31.296s]
Masking reference...  [31.356s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.246s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.049s]
Building query seed array...  [1.503s]
Computing hash join...  [4.994s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [53.496s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.667s]
Building query seed array...  [1.805s]
Computing hash join...  [5.037s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [33.788s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.481s]
Building query seed array...  [1.898s]
Computing hash join...  [4.898s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [30.188s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.597s]
Building query seed array...  [1.542s]
Computing hash join...  [4.937s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [27.272s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.095s]
Building query seed array...  [1.395s]
Computing hash join...  [4.851s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [30.18s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.227s]
Building query seed array...  [1.594s]
Computing hash join...  [4.755s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [22.666s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.444s]
Building query seed array...  [1.724s]
Computing hash join...  [4.777s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [24.855s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.346s]
Building query seed array...  [1.387s]
Computing hash join...  [4.72s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [22.003s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.118s]
Clearing query masking...  [1.226s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [9.009s]
Sorting trace points...  [1.683s]
Computing alignments...  [43.105s]
Deallocating buffers...  [0.035s]
Loading trace points...  [0.108s]
Sorting trace points...  [1.325s]
Computing alignments...  [42.308s]
Deallocating buffers...  [0.032s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.493s]
Computing alignments...  [46.682s]
Deallocating buffers...  [0.129s]
Loading trace points...  [0.129s]
Sorting trace points...  [1.592s]
Computing alignments...  [42.531s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.485s]
Computing alignments...  [45.259s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.714s]
Computing alignments...  [46.276s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.726s]
Computing alignments...  [46.161s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0s]
Sorting trace points...  [1.531s]
Computing alignments...  [45.914s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0s]
 [380.724s]
Deallocating reference...  [0.072s]
Loading reference sequences...  [35.126s]
Masking reference...  [31.081s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [33.074s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.523s]
Building query seed array...  [1.512s]
Computing hash join...  [4.891s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [54.383s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.763s]
Building query seed array...  [1.809s]
Computing hash join...  [4.969s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [34.929s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.174s]
Building query seed array...  [1.89s]
Computing hash join...  [4.927s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [32.246s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.198s]
Building query seed array...  [1.539s]
Computing hash join...  [4.915s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [26.382s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.843s]
Building query seed array...  [1.401s]
Computing hash join...  [4.75s]
Masking low complexity seeds...  [0.2s]
Searching alignments...  [29.532s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.409s]
Building query seed array...  [1.595s]
Computing hash join...  [4.771s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [22.605s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.266s]
Building query seed array...  [1.7s]
Computing hash join...  [4.77s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [24.897s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.214s]
Building query seed array...  [1.427s]
Computing hash join...  [4.82s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [20.821s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.131s]
Clearing query masking...  [1.221s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [8.913s]
Sorting trace points...  [1.675s]
Computing alignments...  [43.096s]
Deallocating buffers...  [0.038s]
Loading trace points...  [0.121s]
Sorting trace points...  [1.609s]
Computing alignments...  [42.491s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.571s]
Computing alignments...  [46.465s]
Deallocating buffers...  [0.138s]
Loading trace points...  [0.119s]
Sorting trace points...  [1.529s]
Computing alignments...  [42.784s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.462s]
Sorting trace points...  [1.336s]
Computing alignments...  [45.407s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.171s]
Sorting trace points...  [1.709s]
Computing alignments...  [46.313s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.18s]
Sorting trace points...  [1.361s]
Computing alignments...  [46.353s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0s]
Sorting trace points...  [1.73s]
Computing alignments...  [46.065s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0s]
 [381.941s]
Deallocating reference...  [0.067s]
Loading reference sequences...  [29.894s]
Masking reference...  [31.394s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.802s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.217s]
Building query seed array...  [1.494s]
Computing hash join...  [4.933s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [52.134s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.57s]
Building query seed array...  [1.821s]
Computing hash join...  [5.006s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [33.18s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.08s]
Building query seed array...  [1.918s]
Computing hash join...  [4.938s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [29.559s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.894s]
Building query seed array...  [1.583s]
Computing hash join...  [4.903s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [27.965s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.107s]
Building query seed array...  [1.419s]
Computing hash join...  [4.808s]
Masking low complexity seeds...  [0.2s]
Searching alignments...  [28.97s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.54s]
Building query seed array...  [1.606s]
Computing hash join...  [4.755s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [22.007s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.444s]
Building query seed array...  [1.691s]
Computing hash join...  [4.8s]
Masking low complexity seeds...  [0.197s]
Searching alignments...  [25.264s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.744s]
Building query seed array...  [1.382s]
Computing hash join...  [4.863s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [21.315s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.201s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [9.076s]
Sorting trace points...  [1.662s]
Computing alignments...  [42.951s]
Deallocating buffers...  [0.04s]
Loading trace points...  [0.118s]
Sorting trace points...  [1.62s]
Computing alignments...  [42.122s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.367s]
Computing alignments...  [46.452s]
Deallocating buffers...  [0.131s]
Loading trace points...  [0.139s]
Sorting trace points...  [1.404s]
Computing alignments...  [42.494s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.139s]
Sorting trace points...  [1.678s]
Computing alignments...  [45.074s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.161s]
Sorting trace points...  [1.691s]
Computing alignments...  [46.161s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.155s]
Sorting trace points...  [1.768s]
Computing alignments...  [46.151s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0s]
Sorting trace points...  [1.42s]
Computing alignments...  [45.786s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0s]
 [380.049s]
Deallocating reference...  [0.067s]
Loading reference sequences...  [31.904s]
Masking reference...  [32.195s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [33s]
Allocating buffers...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.207s]
Building query seed array...  [1.538s]
Computing hash join...  [4.97s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [52.006s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.394s]
Building query seed array...  [1.876s]
Computing hash join...  [4.922s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [33.852s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.44s]
Building query seed array...  [1.882s]
Computing hash join...  [4.916s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [30.055s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.199s]
Building query seed array...  [1.586s]
Computing hash join...  [5.024s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [25.938s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.898s]
Building query seed array...  [1.329s]
Computing hash join...  [4.699s]
Masking low complexity seeds...  [0.196s]
Searching alignments...  [28.108s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.668s]
Building query seed array...  [1.64s]
Computing hash join...  [4.757s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [22.661s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.127s]
Building query seed array...  [1.726s]
Computing hash join...  [4.782s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [23.77s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.795s]
Building query seed array...  [1.432s]
Computing hash join...  [4.693s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [20.268s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.121s]
Clearing query masking...  [1.223s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [8.919s]
Sorting trace points...  [1.612s]
Computing alignments...  [42.538s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0.213s]
Sorting trace points...  [1.299s]
Computing alignments...  [41.958s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.163s]
Sorting trace points...  [1.67s]
Computing alignments...  [45.637s]
Deallocating buffers...  [0.212s]
Loading trace points...  [0.123s]
Sorting trace points...  [1.581s]
Computing alignments...  [42.142s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.174s]
Sorting trace points...  [1.318s]
Computing alignments...  [44.807s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.174s]
Sorting trace points...  [1.402s]
Computing alignments...  [45.883s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.152s]
Sorting trace points...  [1.734s]
Computing alignments...  [45.802s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0s]
Sorting trace points...  [1.389s]
Computing alignments...  [45.559s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0s]
 [376.873s]
Deallocating reference...  [0.063s]
Loading reference sequences...  [29.718s]
Masking reference...  [30.892s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [33.598s]
Allocating buffers...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.462s]
Building query seed array...  [1.562s]
Computing hash join...  [4.951s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [53.669s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.475s]
Building query seed array...  [1.795s]
Computing hash join...  [4.98s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [36.125s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.272s]
Building query seed array...  [1.854s]
Computing hash join...  [4.986s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [32.223s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.558s]
Building query seed array...  [1.513s]
Computing hash join...  [4.967s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [27.157s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.463s]
Building query seed array...  [1.418s]
Computing hash join...  [4.769s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [29.259s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.489s]
Building query seed array...  [1.606s]
Computing hash join...  [4.692s]
Masking low complexity seeds...  [0.2s]
Searching alignments...  [22.024s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.141s]
Building query seed array...  [1.698s]
Computing hash join...  [4.767s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [26.124s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.829s]
Building query seed array...  [1.334s]
Computing hash join...  [4.76s]
Masking low complexity seeds...  [0.2s]
Searching alignments...  [21.257s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.122s]
Clearing query masking...  [1.213s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [8.871s]
Sorting trace points...  [1.614s]
Computing alignments...  [43.224s]
Deallocating buffers...  [0.035s]
Loading trace points...  [0.134s]
Sorting trace points...  [1.592s]
Computing alignments...  [42.207s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.1s]
Sorting trace points...  [1.419s]
Computing alignments...  [46.544s]
Deallocating buffers...  [0.154s]
Loading trace points...  [0.129s]
Sorting trace points...  [1.596s]
Computing alignments...  [42.505s]
Deallocating buffers...  [0.032s]
Loading trace points...  [0.084s]
Sorting trace points...  [1.423s]
Computing alignments...  [45.1s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.832s]
Computing alignments...  [46.143s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.458s]
Computing alignments...  [46.098s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0s]
Sorting trace points...  [1.38s]
Computing alignments...  [45.856s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0s]
 [379.899s]
Deallocating reference...  [0.067s]
Loading reference sequences...  [29.717s]
Masking reference...  [30.875s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.629s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.355s]
Building query seed array...  [1.529s]
Computing hash join...  [4.908s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [51.94s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.629s]
Building query seed array...  [1.789s]
Computing hash join...  [4.963s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [33.442s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.637s]
Building query seed array...  [1.867s]
Computing hash join...  [4.833s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [30.36s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.982s]
Building query seed array...  [1.526s]
Computing hash join...  [4.917s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [26.337s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.181s]
Building query seed array...  [1.467s]
Computing hash join...  [4.728s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [30.752s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.111s]
Building query seed array...  [1.609s]
Computing hash join...  [4.708s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [22.391s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.841s]
Building query seed array...  [1.665s]
Computing hash join...  [4.726s]
Masking low complexity seeds...  [0.198s]
Searching alignments...  [24.421s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.083s]
Building query seed array...  [1.409s]
Computing hash join...  [4.713s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [21.81s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.199s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [9.187s]
Sorting trace points...  [1.636s]
Computing alignments...  [43.027s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0.12s]
Sorting trace points...  [1.336s]
Computing alignments...  [42.161s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.002s]
Sorting trace points...  [1.603s]
Computing alignments...  [45.875s]
Deallocating buffers...  [0.147s]
Loading trace points...  [0.168s]
Sorting trace points...  [1.35s]
Computing alignments...  [42.615s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.669s]
Computing alignments...  [45.251s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.469s]
Computing alignments...  [46.118s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.431s]
Computing alignments...  [46.127s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0s]
Sorting trace points...  [1.545s]
Computing alignments...  [45.856s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0s]
 [379.169s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [29.712s]
Masking reference...  [32.137s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.588s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.25s]
Building query seed array...  [1.511s]
Computing hash join...  [4.946s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [54.091s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.458s]
Building query seed array...  [1.78s]
Computing hash join...  [4.953s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [34.907s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.788s]
Building query seed array...  [1.922s]
Computing hash join...  [4.889s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [30.344s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.016s]
Building query seed array...  [1.514s]
Computing hash join...  [4.979s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [26.97s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.157s]
Building query seed array...  [1.419s]
Computing hash join...  [4.794s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [29.594s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.42s]
Building query seed array...  [1.634s]
Computing hash join...  [4.699s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [22.089s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.193s]
Building query seed array...  [1.691s]
Computing hash join...  [4.79s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [24.274s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.072s]
Building query seed array...  [1.396s]
Computing hash join...  [4.727s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [21.499s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.23s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [8.892s]
Sorting trace points...  [1.609s]
Computing alignments...  [42.783s]
Deallocating buffers...  [0.032s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.333s]
Computing alignments...  [42.065s]
Deallocating buffers...  [0.034s]
Loading trace points...  [0.172s]
Sorting trace points...  [1.623s]
Computing alignments...  [45.993s]
Deallocating buffers...  [0.14s]
Loading trace points...  [0.136s]
Sorting trace points...  [1.438s]
Computing alignments...  [42.315s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.335s]
Sorting trace points...  [1.432s]
Computing alignments...  [45.03s]
Deallocating buffers...  [0.032s]
Loading trace points...  [0.159s]
Sorting trace points...  [1.789s]
Computing alignments...  [46.058s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.126s]
Sorting trace points...  [1.415s]
Computing alignments...  [46.04s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0s]
Sorting trace points...  [1.518s]
Computing alignments...  [45.721s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0s]
 [378.459s]
Deallocating reference...  [0.065s]
Loading reference sequences...  [31.957s]
Masking reference...  [32.084s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.484s]
Allocating buffers...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.194s]
Building query seed array...  [1.565s]
Computing hash join...  [4.956s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [54.378s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.912s]
Building query seed array...  [1.789s]
Computing hash join...  [4.857s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [33.628s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.605s]
Building query seed array...  [1.919s]
Computing hash join...  [4.865s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [31.105s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.111s]
Building query seed array...  [1.537s]
Computing hash join...  [4.868s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [27.174s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.687s]
Building query seed array...  [1.366s]
Computing hash join...  [4.706s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [29.384s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.584s]
Building query seed array...  [1.636s]
Computing hash join...  [4.74s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [21.82s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.453s]
Building query seed array...  [1.688s]
Computing hash join...  [4.792s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [25.112s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.849s]
Building query seed array...  [1.433s]
Computing hash join...  [4.838s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [21.617s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.12s]
Clearing query masking...  [1.165s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [8.82s]
Sorting trace points...  [1.631s]
Computing alignments...  [42.817s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.138s]
Sorting trace points...  [1.373s]
Computing alignments...  [42.171s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.176s]
Sorting trace points...  [1.545s]
Computing alignments...  [45.458s]
Deallocating buffers...  [0.068s]
Loading trace points...  [0.167s]
Sorting trace points...  [1.689s]
Computing alignments...  [42.351s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.175s]
Sorting trace points...  [1.32s]
Computing alignments...  [45.042s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.154s]
Sorting trace points...  [1.796s]
Computing alignments...  [46.084s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.16s]
Sorting trace points...  [1.675s]
Computing alignments...  [46.083s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0s]
Sorting trace points...  [1.543s]
Computing alignments...  [45.813s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
 [378.532s]
Deallocating reference...  [0.066s]
Loading reference sequences...  [29.631s]
Masking reference...  [30.859s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.796s]
Allocating buffers...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.23s]
Building query seed array...  [1.576s]
Computing hash join...  [5.135s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [51.707s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.366s]
Building query seed array...  [1.785s]
Computing hash join...  [4.993s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [32.831s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.637s]
Building query seed array...  [1.897s]
Computing hash join...  [4.898s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [29.674s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.888s]
Building query seed array...  [1.557s]
Computing hash join...  [4.981s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [26.047s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.041s]
Building query seed array...  [1.362s]
Computing hash join...  [4.829s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [29.941s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.79s]
Building query seed array...  [1.632s]
Computing hash join...  [4.863s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [22.408s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.129s]
Building query seed array...  [1.707s]
Computing hash join...  [4.81s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [25.1s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.091s]
Building query seed array...  [1.397s]
Computing hash join...  [4.776s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [21.084s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.222s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [8.994s]
Sorting trace points...  [1.323s]
Computing alignments...  [42.637s]
Deallocating buffers...  [0.035s]
Loading trace points...  [0.166s]
Sorting trace points...  [1.222s]
Computing alignments...  [41.96s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.19s]
Sorting trace points...  [1.474s]
Computing alignments...  [45.518s]
Deallocating buffers...  [0.197s]
Loading trace points...  [0.14s]
Sorting trace points...  [1.249s]
Computing alignments...  [42.126s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.152s]
Sorting trace points...  [1.356s]
Computing alignments...  [44.867s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.138s]
Sorting trace points...  [1.821s]
Computing alignments...  [45.836s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.13s]
Sorting trace points...  [1.463s]
Computing alignments...  [45.872s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0s]
Sorting trace points...  [1.764s]
Computing alignments...  [45.559s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
 [376.383s]
Deallocating reference...  [0.066s]
Loading reference sequences...  [244.246s]
Masking reference...  [31.249s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.943s]
Allocating buffers...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.281s]
Building query seed array...  [1.571s]
Computing hash join...  [5.059s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [52.098s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.489s]
Building query seed array...  [1.756s]
Computing hash join...  [4.982s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [33.685s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.264s]
Building query seed array...  [1.915s]
Computing hash join...  [4.966s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [30.688s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.761s]
Building query seed array...  [1.541s]
Computing hash join...  [4.967s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [26.79s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.3s]
Building query seed array...  [1.429s]
Computing hash join...  [4.818s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [30.008s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.536s]
Building query seed array...  [1.62s]
Computing hash join...  [4.747s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [22.283s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.861s]
Building query seed array...  [1.721s]
Computing hash join...  [4.82s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [25.601s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.106s]
Building query seed array...  [1.363s]
Computing hash join...  [4.901s]
Masking low complexity seeds...  [0.2s]
Searching alignments...  [21.903s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.119s]
Clearing query masking...  [1.237s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [8.82s]
Sorting trace points...  [1.606s]
Computing alignments...  [42.958s]
Deallocating buffers...  [0.037s]
Loading trace points...  [0.101s]
Sorting trace points...  [1.378s]
Computing alignments...  [42.132s]
Deallocating buffers...  [0.025s]
Loading trace points...  [1.319s]
Sorting trace points...  [1.585s]
Computing alignments...  [45.798s]
Deallocating buffers...  [0.136s]
Loading trace points...  [0.125s]
Sorting trace points...  [1.688s]
Computing alignments...  [42.401s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.71s]
Computing alignments...  [45.031s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.151s]
Sorting trace points...  [1.516s]
Computing alignments...  [46.096s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.172s]
Sorting trace points...  [1.312s]
Computing alignments...  [46.164s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0s]
Sorting trace points...  [1.711s]
Computing alignments...  [45.807s]
Deallocating buffers...  [0.032s]
Loading trace points...  [0s]
 [380.048s]
Deallocating reference...  [0.066s]
Loading reference sequences...  [29.92s]
Masking reference...  [30.849s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.849s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.102s]
Building query seed array...  [1.489s]
Computing hash join...  [4.996s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [54.649s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.333s]
Building query seed array...  [1.828s]
Computing hash join...  [4.883s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [34.229s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.09s]
Building query seed array...  [1.867s]
Computing hash join...  [4.853s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [33.025s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.016s]
Building query seed array...  [1.53s]
Computing hash join...  [4.929s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [26.777s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.693s]
Building query seed array...  [1.398s]
Computing hash join...  [4.85s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [29.57s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.268s]
Building query seed array...  [1.598s]
Computing hash join...  [4.776s]
Masking low complexity seeds...  [0.2s]
Searching alignments...  [21.927s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.949s]
Building query seed array...  [1.749s]
Computing hash join...  [4.856s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [25.995s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.116s]
Building query seed array...  [1.427s]
Computing hash join...  [4.731s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [21.534s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.134s]
Clearing query masking...  [1.214s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [9.449s]
Sorting trace points...  [1.641s]
Computing alignments...  [42.988s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.62s]
Computing alignments...  [42.325s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.152s]
Sorting trace points...  [1.249s]
Computing alignments...  [45.619s]
Deallocating buffers...  [0.116s]
Loading trace points...  [0.127s]
Sorting trace points...  [1.365s]
Computing alignments...  [42.412s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.608s]
Sorting trace points...  [1.545s]
Computing alignments...  [45.02s]
Deallocating buffers...  [0.034s]
Loading trace points...  [0.169s]
Sorting trace points...  [1.39s]
Computing alignments...  [45.959s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.166s]
Sorting trace points...  [1.699s]
Computing alignments...  [45.992s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0s]
Sorting trace points...  [1.526s]
Computing alignments...  [45.748s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0s]
 [379.241s]
Deallocating reference...  [0.064s]
Loading reference sequences...  [23.779s]
Masking reference...  [25.005s]
Initializing dictionary...  [0.063s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [26.423s]
Allocating buffers...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.481s]
Building query seed array...  [1.537s]
Computing hash join...  [4.068s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [43.802s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [10.361s]
Building query seed array...  [1.832s]
Computing hash join...  [4.18s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [28.676s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [10.841s]
Building query seed array...  [1.928s]
Computing hash join...  [4.1s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [24.595s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [7.816s]
Building query seed array...  [1.494s]
Computing hash join...  [4.18s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [21.923s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [8.262s]
Building query seed array...  [1.447s]
Computing hash join...  [3.947s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [24.059s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [9.901s]
Building query seed array...  [1.66s]
Computing hash join...  [4.023s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [18.923s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [10.722s]
Building query seed array...  [1.658s]
Computing hash join...  [3.989s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [19.358s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [8.415s]
Building query seed array...  [1.394s]
Computing hash join...  [3.94s]
Masking low complexity seeds...  [0.193s]
Searching alignments...  [17.342s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.109s]
Clearing query masking...  [1.244s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [11.561s]
Sorting trace points...  [2.015s]
Computing alignments...  [50.511s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.695s]
Computing alignments...  [52.189s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.168s]
Sorting trace points...  [1.969s]
Computing alignments...  [51.182s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.171s]
Sorting trace points...  [1.832s]
Computing alignments...  [54.96s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.677s]
Computing alignments...  [54.678s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0s]
Sorting trace points...  [0.724s]
Computing alignments...  [18.285s]
Deallocating buffers...  [0.008s]
Loading trace points...  [0s]
 [304s]
Deallocating reference...  [0.054s]
Loading reference sequences...  [0.105s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [1367.24s]
 [1367.24s]
Deallocating queries...  [0.039s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [3.903s]
 [5.002s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 13617.7s
Reported 1723090526 pairwise alignments, 1723090526 HSPs.
9886081 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C29_R2.fastp-trim.20230215.fq.gz complete: C29_R2.blastx.meganized.daa

Now MEGANizing C29_R2.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: C29_R2.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 100% (240.2s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.2s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (3,221.7s)
Total reads:        9,886,081
With hits:           9,886,081 
Alignments:      1,691,771,870
Assig. Taxonomy:     9,119,982
Assig. SEED:            80,417
Assig. EGGNOG:          43,464
Assig. GTDB:           293,289
Assig. EC:           1,511,061
Assig. INTERPRO2GO:    831,966
MinSupport set to: 4943
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.4s)
Min-supp. changes:       3,916
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (6.4s)
Min-supp. changes:       2,995
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (16.6s)
Binning reads Syncing
100% (0.4s)
Class. Taxonomy:            63
Class. SEED:               503
Class. EGGNOG:           1,771
Class. GTDB:                21
Class. EC:               2,335
Class. INTERPRO2GO:      7,509
Total time:  3,495s
Peak memory: 33.8 of 195.3G
MEGANization of C29_R2.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C30_R1.fastp-trim.20230215.fq.gz...
6c3295cbba65a4a73a40ff12bd7af3d1  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C30_R1.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C30_R1.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.333s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.698s]
Opening the output file...  [0s]
Loading query sequences...  [80.836s]
Masking queries...  [20.574s]
Algorithm: Double-indexed
Building query histograms...  [23.202s]
Loading reference sequences...  [29.533s]
Masking reference...  [30.873s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.178s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.697s]
Building query seed array...  [2.286s]
Computing hash join...  [5.298s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [85.335s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.31s]
Building query seed array...  [2.613s]
Computing hash join...  [5.091s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [53.122s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.57s]
Building query seed array...  [2.781s]
Computing hash join...  [5.094s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [46.927s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.604s]
Building query seed array...  [2.143s]
Computing hash join...  [5.163s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [41.37s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.722s]
Building query seed array...  [2.07s]
Computing hash join...  [4.922s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [42.615s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.38s]
Building query seed array...  [2.404s]
Computing hash join...  [4.936s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [33.568s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.016s]
Building query seed array...  [2.475s]
Computing hash join...  [4.906s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [36.866s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.934s]
Building query seed array...  [2.06s]
Computing hash join...  [4.948s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [33.236s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.132s]
Clearing query masking...  [1.736s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.649s]
Sorting trace points...  [1.383s]
Computing alignments...  [34.027s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.256s]
Computing alignments...  [34.262s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.276s]
Computing alignments...  [33.959s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.293s]
Computing alignments...  [33.922s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.452s]
Sorting trace points...  [1.295s]
Computing alignments...  [34.159s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.221s]
Computing alignments...  [34.533s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.283s]
Computing alignments...  [34.071s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.087s]
Sorting trace points...  [1.288s]
Computing alignments...  [33.633s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.312s]
Computing alignments...  [34.778s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.388s]
Computing alignments...  [35.934s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.335s]
Computing alignments...  [35.889s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.28s]
Computing alignments...  [35.981s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.173s]
Computing alignments...  [35.995s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.038s]
Computing alignments...  [35.913s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.16s]
Computing alignments...  [35.912s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.342s]
Computing alignments...  [35.81s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
 [587.236s]
Deallocating reference...  [0.075s]
Loading reference sequences...  [30.119s]
Masking reference...  [31.949s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.448s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.293s]
Building query seed array...  [2.202s]
Computing hash join...  [5.144s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [82.07s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.189s]
Building query seed array...  [2.632s]
Computing hash join...  [5.162s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [53.323s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.443s]
Building query seed array...  [2.753s]
Computing hash join...  [5.05s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [45.916s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.05s]
Building query seed array...  [2.231s]
Computing hash join...  [5.222s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [40.669s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.984s]
Building query seed array...  [2.037s]
Computing hash join...  [4.842s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [41.817s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.435s]
Building query seed array...  [2.305s]
Computing hash join...  [4.887s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [33.541s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.453s]
Building query seed array...  [2.5s]
Computing hash join...  [4.835s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [35.685s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.144s]
Building query seed array...  [2.068s]
Computing hash join...  [4.9s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [31.45s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.131s]
Clearing query masking...  [1.69s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.738s]
Sorting trace points...  [1.365s]
Computing alignments...  [33.875s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.093s]
Sorting trace points...  [1.254s]
Computing alignments...  [34.184s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.273s]
Computing alignments...  [34.037s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.173s]
Computing alignments...  [33.853s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.921s]
Sorting trace points...  [1.33s]
Computing alignments...  [34.066s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.297s]
Computing alignments...  [34.457s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.302s]
Computing alignments...  [34.069s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.085s]
Sorting trace points...  [1.196s]
Computing alignments...  [33.542s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.336s]
Computing alignments...  [34.682s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.835s]
Sorting trace points...  [1.078s]
Computing alignments...  [35.845s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.09s]
Sorting trace points...  [1.366s]
Computing alignments...  [35.734s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.262s]
Computing alignments...  [35.79s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.207s]
Computing alignments...  [35.824s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.333s]
Computing alignments...  [35.888s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.037s]
Sorting trace points...  [1.335s]
Computing alignments...  [35.946s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.326s]
Computing alignments...  [35.741s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
 [587.619s]
Deallocating reference...  [0.077s]
Loading reference sequences...  [34.483s]
Masking reference...  [31.168s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [31.884s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.343s]
Building query seed array...  [2.208s]
Computing hash join...  [5.071s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [82.669s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.398s]
Building query seed array...  [2.583s]
Computing hash join...  [5.129s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [53.602s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.899s]
Building query seed array...  [2.75s]
Computing hash join...  [5.088s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [45.96s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.163s]
Building query seed array...  [2.214s]
Computing hash join...  [5.086s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [42.885s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.159s]
Building query seed array...  [2.014s]
Computing hash join...  [4.904s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [42.013s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.136s]
Building query seed array...  [2.305s]
Computing hash join...  [4.847s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [34.01s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.572s]
Building query seed array...  [2.524s]
Computing hash join...  [4.916s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [36.858s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.13s]
Building query seed array...  [2.053s]
Computing hash join...  [4.833s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [32.205s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.681s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.889s]
Sorting trace points...  [1.342s]
Computing alignments...  [33.923s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.291s]
Computing alignments...  [34.224s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.841s]
Sorting trace points...  [1.298s]
Computing alignments...  [34.024s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.287s]
Computing alignments...  [33.912s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.342s]
Computing alignments...  [34.114s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.346s]
Computing alignments...  [34.55s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.312s]
Computing alignments...  [34.114s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.303s]
Sorting trace points...  [1.108s]
Computing alignments...  [33.654s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.325s]
Computing alignments...  [34.886s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.128s]
Computing alignments...  [36.074s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.389s]
Computing alignments...  [35.905s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.254s]
Computing alignments...  [36.033s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.218s]
Computing alignments...  [35.98s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.322s]
Computing alignments...  [35.975s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.039s]
Sorting trace points...  [1.364s]
Computing alignments...  [35.944s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.316s]
Computing alignments...  [35.754s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
 [588.726s]
Deallocating reference...  [0.074s]
Loading reference sequences...  [29.667s]
Masking reference...  [30.845s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [33.118s]
Allocating buffers...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.323s]
Building query seed array...  [2.251s]
Computing hash join...  [5.245s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [82.185s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.295s]
Building query seed array...  [2.653s]
Computing hash join...  [5.112s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [52.186s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [14.07s]
Building query seed array...  [2.799s]
Computing hash join...  [5.06s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [46.665s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.161s]
Building query seed array...  [2.299s]
Computing hash join...  [5.291s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [41.228s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.032s]
Building query seed array...  [2.03s]
Computing hash join...  [4.99s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [42.885s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.695s]
Building query seed array...  [2.272s]
Computing hash join...  [4.923s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [33.645s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.01s]
Building query seed array...  [2.459s]
Computing hash join...  [4.911s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [37.01s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.002s]
Building query seed array...  [2.024s]
Computing hash join...  [5.059s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [32.201s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.718s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.733s]
Sorting trace points...  [1.359s]
Computing alignments...  [34.094s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.33s]
Computing alignments...  [34.374s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.303s]
Computing alignments...  [33.965s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.1s]
Sorting trace points...  [0.962s]
Computing alignments...  [33.858s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.18s]
Computing alignments...  [34.101s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.004s]
Computing alignments...  [34.459s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.089s]
Sorting trace points...  [1.173s]
Computing alignments...  [34.052s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.218s]
Computing alignments...  [33.647s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.045s]
Sorting trace points...  [0.983s]
Computing alignments...  [34.751s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.248s]
Computing alignments...  [35.885s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.332s]
Computing alignments...  [35.721s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.023s]
Computing alignments...  [35.828s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.336s]
Computing alignments...  [35.914s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.336s]
Computing alignments...  [35.87s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.405s]
Computing alignments...  [35.892s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0s]
Sorting trace points...  [1.116s]
Computing alignments...  [35.822s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0s]
 [585.426s]
Deallocating reference...  [0.077s]
Loading reference sequences...  [29.632s]
Masking reference...  [32.159s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.268s]
Allocating buffers...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.252s]
Building query seed array...  [2.293s]
Computing hash join...  [5.18s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [80.964s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.754s]
Building query seed array...  [2.685s]
Computing hash join...  [5.138s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [51.305s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.124s]
Building query seed array...  [2.762s]
Computing hash join...  [5.129s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [45.446s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.263s]
Building query seed array...  [2.225s]
Computing hash join...  [5.303s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [42.037s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.001s]
Building query seed array...  [1.999s]
Computing hash join...  [5.051s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [41.814s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.208s]
Building query seed array...  [2.358s]
Computing hash join...  [4.925s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [33.279s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.721s]
Building query seed array...  [2.438s]
Computing hash join...  [4.947s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [36.592s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.917s]
Building query seed array...  [2.118s]
Computing hash join...  [4.894s]
Masking low complexity seeds...  [0.2s]
Searching alignments...  [32.217s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.131s]
Clearing query masking...  [1.727s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.727s]
Sorting trace points...  [1.334s]
Computing alignments...  [33.848s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.276s]
Computing alignments...  [34.059s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.247s]
Computing alignments...  [33.88s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.301s]
Computing alignments...  [33.726s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.294s]
Computing alignments...  [33.996s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.319s]
Computing alignments...  [34.479s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.253s]
Computing alignments...  [33.982s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.22s]
Computing alignments...  [33.495s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.281s]
Computing alignments...  [34.651s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.342s]
Computing alignments...  [35.779s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.314s]
Computing alignments...  [35.642s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.355s]
Computing alignments...  [35.701s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.298s]
Computing alignments...  [35.745s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.356s]
Computing alignments...  [35.703s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.029s]
Sorting trace points...  [1.329s]
Computing alignments...  [35.737s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.278s]
Computing alignments...  [35.625s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [584.689s]
Deallocating reference...  [0.073s]
Loading reference sequences...  [240.652s]
Masking reference...  [32.126s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.103s]
Allocating buffers...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [9.938s]
Building query seed array...  [2.245s]
Computing hash join...  [5.12s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [79.477s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.067s]
Building query seed array...  [2.633s]
Computing hash join...  [5.134s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [52.418s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [12.951s]
Building query seed array...  [2.835s]
Computing hash join...  [5.055s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [46.303s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.232s]
Building query seed array...  [2.204s]
Computing hash join...  [5.183s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [41.531s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.01s]
Building query seed array...  [2.003s]
Computing hash join...  [4.92s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [41.695s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.485s]
Building query seed array...  [2.394s]
Computing hash join...  [4.848s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [33.915s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [14.25s]
Building query seed array...  [2.516s]
Computing hash join...  [4.978s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [36.604s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.815s]
Building query seed array...  [2.057s]
Computing hash join...  [4.934s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [32.147s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.656s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.645s]
Sorting trace points...  [1.334s]
Computing alignments...  [33.692s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.285s]
Computing alignments...  [34.031s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.239s]
Computing alignments...  [33.728s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.241s]
Computing alignments...  [33.605s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.074s]
Computing alignments...  [33.858s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.107s]
Sorting trace points...  [1.045s]
Computing alignments...  [34.231s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.164s]
Computing alignments...  [33.814s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.25s]
Computing alignments...  [33.332s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.012s]
Computing alignments...  [34.485s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.335s]
Computing alignments...  [35.642s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.332s]
Computing alignments...  [35.609s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.091s]
Sorting trace points...  [1.31s]
Computing alignments...  [35.539s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.323s]
Computing alignments...  [35.609s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.088s]
Sorting trace points...  [1.398s]
Computing alignments...  [35.565s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.403s]
Computing alignments...  [35.649s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.341s]
Computing alignments...  [35.507s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0s]
 [581.864s]
Deallocating reference...  [0.081s]
Loading reference sequences...  [29.607s]
Masking reference...  [32.06s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.206s]
Allocating buffers...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.242s]
Building query seed array...  [2.242s]
Computing hash join...  [5.176s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [82.874s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.262s]
Building query seed array...  [2.676s]
Computing hash join...  [5.159s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [54.548s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.109s]
Building query seed array...  [2.788s]
Computing hash join...  [5.03s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [48.274s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.864s]
Building query seed array...  [2.22s]
Computing hash join...  [5.193s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [43.12s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.122s]
Building query seed array...  [1.972s]
Computing hash join...  [4.943s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [42.528s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.894s]
Building query seed array...  [2.272s]
Computing hash join...  [4.849s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [33.357s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.098s]
Building query seed array...  [2.538s]
Computing hash join...  [4.917s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [37.389s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.058s]
Building query seed array...  [1.97s]
Computing hash join...  [4.891s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [32.941s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.71s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.736s]
Sorting trace points...  [1.305s]
Computing alignments...  [34.04s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.256s]
Sorting trace points...  [1.309s]
Computing alignments...  [34.176s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.269s]
Computing alignments...  [33.949s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.288s]
Computing alignments...  [33.874s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.287s]
Computing alignments...  [34.067s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.278s]
Computing alignments...  [34.589s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.291s]
Sorting trace points...  [1.223s]
Computing alignments...  [34.044s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.249s]
Computing alignments...  [33.561s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.114s]
Sorting trace points...  [1.362s]
Computing alignments...  [34.673s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.041s]
Computing alignments...  [35.853s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.409s]
Computing alignments...  [35.693s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.301s]
Computing alignments...  [35.818s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.412s]
Computing alignments...  [35.837s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.001s]
Sorting trace points...  [0.991s]
Computing alignments...  [35.835s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.284s]
Computing alignments...  [35.838s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.278s]
Computing alignments...  [35.854s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
 [586.301s]
Deallocating reference...  [0.074s]
Loading reference sequences...  [29.714s]
Masking reference...  [30.856s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.523s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.535s]
Building query seed array...  [2.197s]
Computing hash join...  [5.222s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [81.374s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.759s]
Building query seed array...  [2.641s]
Computing hash join...  [5.095s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [54.35s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.812s]
Building query seed array...  [2.755s]
Computing hash join...  [5.19s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [47.598s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.098s]
Building query seed array...  [2.241s]
Computing hash join...  [5.145s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [41.489s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.92s]
Building query seed array...  [2.03s]
Computing hash join...  [4.957s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [42.081s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.962s]
Building query seed array...  [2.356s]
Computing hash join...  [4.864s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [33.498s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.373s]
Building query seed array...  [2.497s]
Computing hash join...  [4.917s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [37.66s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.965s]
Building query seed array...  [2.165s]
Computing hash join...  [4.908s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [31.606s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.737s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.896s]
Sorting trace points...  [1.344s]
Computing alignments...  [33.975s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.286s]
Computing alignments...  [34.195s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.258s]
Computing alignments...  [33.941s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.285s]
Computing alignments...  [33.883s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.197s]
Computing alignments...  [34.043s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.084s]
Sorting trace points...  [1.302s]
Computing alignments...  [34.485s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.097s]
Sorting trace points...  [1.156s]
Computing alignments...  [34.001s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.042s]
Computing alignments...  [33.587s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.171s]
Computing alignments...  [34.751s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.351s]
Computing alignments...  [35.897s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.36s]
Computing alignments...  [35.825s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.354s]
Computing alignments...  [35.874s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.379s]
Computing alignments...  [35.897s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.38s]
Computing alignments...  [35.852s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.33s]
Computing alignments...  [35.936s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.348s]
Computing alignments...  [35.79s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
 [586.531s]
Deallocating reference...  [0.076s]
Loading reference sequences...  [29.722s]
Masking reference...  [30.85s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.698s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.222s]
Building query seed array...  [2.259s]
Computing hash join...  [5.085s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [82.942s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.651s]
Building query seed array...  [2.542s]
Computing hash join...  [5.18s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [53.897s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.381s]
Building query seed array...  [2.667s]
Computing hash join...  [5.131s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [45.893s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.33s]
Building query seed array...  [2.225s]
Computing hash join...  [5.077s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [40.801s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.301s]
Building query seed array...  [1.999s]
Computing hash join...  [4.955s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [42.779s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.12s]
Building query seed array...  [2.289s]
Computing hash join...  [5.002s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [33.329s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.531s]
Building query seed array...  [2.468s]
Computing hash join...  [4.939s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [37.376s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.13s]
Building query seed array...  [2.044s]
Computing hash join...  [4.856s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [32.556s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.737s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.863s]
Sorting trace points...  [1.291s]
Computing alignments...  [34.159s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.066s]
Sorting trace points...  [0.979s]
Computing alignments...  [34.402s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.266s]
Computing alignments...  [33.97s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.164s]
Computing alignments...  [33.999s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.278s]
Computing alignments...  [34.135s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.001s]
Computing alignments...  [34.696s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.095s]
Sorting trace points...  [1.199s]
Computing alignments...  [34.069s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.096s]
Sorting trace points...  [1.262s]
Computing alignments...  [33.623s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.329s]
Computing alignments...  [34.782s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.28s]
Computing alignments...  [35.938s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.234s]
Computing alignments...  [35.838s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.088s]
Sorting trace points...  [1.337s]
Computing alignments...  [35.859s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.112s]
Sorting trace points...  [1.019s]
Computing alignments...  [35.832s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.084s]
Sorting trace points...  [1.385s]
Computing alignments...  [35.782s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.455s]
Sorting trace points...  [1.346s]
Computing alignments...  [35.925s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.336s]
Computing alignments...  [35.67s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
 [586.997s]
Deallocating reference...  [0.078s]
Loading reference sequences...  [29.616s]
Masking reference...  [30.846s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.445s]
Allocating buffers...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.03s]
Building query seed array...  [2.187s]
Computing hash join...  [5.121s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [84.704s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.806s]
Building query seed array...  [2.548s]
Computing hash join...  [5.147s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [54.218s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.794s]
Building query seed array...  [2.792s]
Computing hash join...  [5.058s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [46.428s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.069s]
Building query seed array...  [2.234s]
Computing hash join...  [5.123s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [41.153s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.997s]
Building query seed array...  [2.042s]
Computing hash join...  [4.979s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [41.842s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.447s]
Building query seed array...  [2.324s]
Computing hash join...  [4.841s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [33.483s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.891s]
Building query seed array...  [2.477s]
Computing hash join...  [4.853s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [36.517s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.124s]
Building query seed array...  [2.136s]
Computing hash join...  [4.934s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [32.401s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.138s]
Clearing query masking...  [1.716s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.701s]
Sorting trace points...  [1.286s]
Computing alignments...  [33.905s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.306s]
Computing alignments...  [34.177s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.211s]
Computing alignments...  [33.93s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.223s]
Computing alignments...  [33.822s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.29s]
Computing alignments...  [34.014s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.277s]
Computing alignments...  [34.406s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.323s]
Computing alignments...  [33.907s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.084s]
Sorting trace points...  [1.015s]
Computing alignments...  [33.485s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.005s]
Computing alignments...  [34.614s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.732s]
Sorting trace points...  [1.379s]
Computing alignments...  [35.827s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.062s]
Computing alignments...  [35.631s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.338s]
Computing alignments...  [35.758s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.041s]
Computing alignments...  [35.809s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.089s]
Sorting trace points...  [1.392s]
Computing alignments...  [35.716s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.042s]
Sorting trace points...  [1.332s]
Computing alignments...  [35.767s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.262s]
Computing alignments...  [35.51s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0s]
 [584.602s]
Deallocating reference...  [0.08s]
Loading reference sequences...  [29.676s]
Masking reference...  [30.826s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.371s]
Allocating buffers...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.184s]
Building query seed array...  [2.213s]
Computing hash join...  [5.161s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [81.441s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.701s]
Building query seed array...  [2.593s]
Computing hash join...  [5.126s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [52.193s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.019s]
Building query seed array...  [2.753s]
Computing hash join...  [5.038s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [46.496s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.754s]
Building query seed array...  [2.267s]
Computing hash join...  [5.148s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [40.748s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.054s]
Building query seed array...  [1.989s]
Computing hash join...  [5.04s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [41.696s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.878s]
Building query seed array...  [2.302s]
Computing hash join...  [4.889s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [33.109s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.241s]
Building query seed array...  [2.454s]
Computing hash join...  [4.921s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [36.258s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.054s]
Building query seed array...  [2.001s]
Computing hash join...  [4.917s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [32.608s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.674s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.655s]
Sorting trace points...  [1.339s]
Computing alignments...  [33.668s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.282s]
Computing alignments...  [34.073s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.267s]
Computing alignments...  [33.802s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.307s]
Computing alignments...  [33.683s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.041s]
Computing alignments...  [33.944s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.327s]
Computing alignments...  [34.362s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.271s]
Computing alignments...  [33.878s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.256s]
Computing alignments...  [33.395s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.001s]
Sorting trace points...  [0.974s]
Computing alignments...  [34.541s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.255s]
Computing alignments...  [35.713s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.338s]
Computing alignments...  [35.586s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.354s]
Computing alignments...  [35.672s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.324s]
Computing alignments...  [35.756s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.017s]
Computing alignments...  [35.756s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.001s]
Sorting trace points...  [1s]
Computing alignments...  [35.758s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.34s]
Computing alignments...  [35.536s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0s]
 [582.594s]
Deallocating reference...  [0.076s]
Loading reference sequences...  [29.675s]
Masking reference...  [32.081s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.702s]
Allocating buffers...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.276s]
Building query seed array...  [2.242s]
Computing hash join...  [5.128s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [83.061s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.413s]
Building query seed array...  [2.588s]
Computing hash join...  [5.089s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [52.931s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.154s]
Building query seed array...  [2.755s]
Computing hash join...  [5.048s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [46.913s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.182s]
Building query seed array...  [2.225s]
Computing hash join...  [5.303s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [41.876s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.012s]
Building query seed array...  [2.013s]
Computing hash join...  [4.898s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [42.717s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.304s]
Building query seed array...  [2.37s]
Computing hash join...  [4.946s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [33.306s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.223s]
Building query seed array...  [2.513s]
Computing hash join...  [4.897s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [36.15s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.757s]
Building query seed array...  [2.012s]
Computing hash join...  [4.904s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [32.607s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.104s]
Clearing query masking...  [1.65s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.731s]
Sorting trace points...  [1.349s]
Computing alignments...  [34.18s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.078s]
Computing alignments...  [34.3s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.078s]
Sorting trace points...  [0.95s]
Computing alignments...  [34.006s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.3s]
Computing alignments...  [33.917s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.544s]
Sorting trace points...  [1.289s]
Computing alignments...  [34.173s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.304s]
Computing alignments...  [34.559s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.189s]
Computing alignments...  [34.084s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.072s]
Sorting trace points...  [0.931s]
Computing alignments...  [33.619s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.205s]
Computing alignments...  [34.824s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.421s]
Computing alignments...  [35.996s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.304s]
Computing alignments...  [35.809s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.371s]
Computing alignments...  [35.915s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.102s]
Sorting trace points...  [1.013s]
Computing alignments...  [36.081s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.306s]
Computing alignments...  [36.034s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.336s]
Computing alignments...  [35.992s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.299s]
Computing alignments...  [35.95s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0s]
 [587.445s]
Deallocating reference...  [0.074s]
Loading reference sequences...  [29.562s]
Masking reference...  [30.828s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.592s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.153s]
Building query seed array...  [2.264s]
Computing hash join...  [5.108s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [82.326s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.42s]
Building query seed array...  [2.529s]
Computing hash join...  [5.101s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [52.527s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.317s]
Building query seed array...  [2.764s]
Computing hash join...  [5.108s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [46.428s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.365s]
Building query seed array...  [2.204s]
Computing hash join...  [5.034s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [41.421s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.864s]
Building query seed array...  [2.114s]
Computing hash join...  [4.893s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [43.144s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.683s]
Building query seed array...  [2.315s]
Computing hash join...  [4.898s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [33.095s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.232s]
Building query seed array...  [2.501s]
Computing hash join...  [4.907s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [36.903s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.949s]
Building query seed array...  [2.03s]
Computing hash join...  [4.94s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [32.193s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.734s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.756s]
Sorting trace points...  [1.227s]
Computing alignments...  [33.908s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.104s]
Sorting trace points...  [1.321s]
Computing alignments...  [34.226s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.274s]
Computing alignments...  [34.011s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.282s]
Computing alignments...  [33.974s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.048s]
Sorting trace points...  [0.997s]
Computing alignments...  [34.205s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.102s]
Sorting trace points...  [0.984s]
Computing alignments...  [34.678s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.075s]
Sorting trace points...  [0.998s]
Computing alignments...  [34.131s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.234s]
Computing alignments...  [33.675s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.101s]
Computing alignments...  [34.813s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.428s]
Computing alignments...  [35.999s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.273s]
Computing alignments...  [35.765s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.115s]
Sorting trace points...  [1.382s]
Computing alignments...  [35.814s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.417s]
Computing alignments...  [35.701s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.354s]
Computing alignments...  [35.74s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.098s]
Computing alignments...  [35.912s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.324s]
Computing alignments...  [35.779s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [586.084s]
Deallocating reference...  [0.064s]
Loading reference sequences...  [25.349s]
Masking reference...  [24.975s]
Initializing dictionary...  [0.064s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [26.569s]
Allocating buffers...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.384s]
Building query seed array...  [2.276s]
Computing hash join...  [4.291s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [66.551s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [10.111s]
Building query seed array...  [2.628s]
Computing hash join...  [4.291s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [41.865s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [10.644s]
Building query seed array...  [2.799s]
Computing hash join...  [4.309s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [37.719s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [8.333s]
Building query seed array...  [2.178s]
Computing hash join...  [4.362s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [33.655s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [8.018s]
Building query seed array...  [1.982s]
Computing hash join...  [4.166s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [34.669s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [10.13s]
Building query seed array...  [2.372s]
Computing hash join...  [4.176s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [28.432s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [10.927s]
Building query seed array...  [2.493s]
Computing hash join...  [4.059s]
Masking low complexity seeds...  [0.199s]
Searching alignments...  [30.25s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [8.576s]
Building query seed array...  [2.064s]
Computing hash join...  [4.189s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [26.345s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.107s]
Clearing query masking...  [1.737s]
Opening temporary output file...  [0.02s]
Computing alignments... Loading trace points...  [11.917s]
Sorting trace points...  [2.24s]
Computing alignments...  [54.195s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.124s]
Sorting trace points...  [2.025s]
Computing alignments...  [53.839s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.187s]
Sorting trace points...  [1.99s]
Computing alignments...  [54.383s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.116s]
Sorting trace points...  [2.035s]
Computing alignments...  [53.745s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.806s]
Computing alignments...  [55.861s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.038s]
Computing alignments...  [28.47s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.055s]
Sorting trace points...  [0.876s]
Computing alignments...  [28.521s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.049s]
Computing alignments...  [28.598s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.105s]
Computing alignments...  [28.565s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.115s]
Computing alignments...  [28.587s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [0.873s]
Computing alignments...  [28.594s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [472.552s]
Deallocating reference...  [0.066s]
Loading reference sequences...  [0.108s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [2114.53s]
 [2114.53s]
Deallocating queries...  [0.065s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [3.892s]
 [5.751s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 19076s
Reported 2748379435 pairwise alignments, 2748379435 HSPs.
14399551 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C30_R1.fastp-trim.20230215.fq.gz complete: C30_R1.blastx.meganized.daa

Now MEGANizing C30_R1.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: C30_R1.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 100% (249.0s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.3s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (5,134.7s)
Total reads:       14,399,551
With hits:          14,399,551 
Alignments:      2,743,446,284
Assig. Taxonomy:    13,476,182
Assig. SEED:           128,489
Assig. EGGNOG:          67,560
Assig. GTDB:           469,294
Assig. EC:           2,492,036
Assig. INTERPRO2GO:  1,392,761
MinSupport set to: 7199
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.4s)
Min-supp. changes:       4,305
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (16.5s)
Min-supp. changes:       3,365
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (51.8s)
Binning reads Syncing
100% (0.3s)
Class. Taxonomy:            65
Class. SEED:               520
Class. EGGNOG:           1,838
Class. GTDB:                24
Class. EC:               2,409
Class. INTERPRO2GO:      7,932
Total time:  5,462s
Peak memory: 33 of 195.3G
MEGANization of C30_R1.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C30_R2.fastp-trim.20230215.fq.gz...
5f1e9f8c6d18efda493b540a37f32c0f  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C30_R2.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C30_R2.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.301s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.766s]
Opening the output file...  [0s]
Loading query sequences...  [83.023s]
Masking queries...  [20.611s]
Algorithm: Double-indexed
Building query histograms...  [22.123s]
Loading reference sequences...  [29.646s]
Masking reference...  [30.828s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.533s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.464s]
Building query seed array...  [2.236s]
Computing hash join...  [5.462s]
Masking low complexity seeds...  [0.269s]
Searching alignments...  [82.174s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.283s]
Building query seed array...  [2.693s]
Computing hash join...  [5.293s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [53.338s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.11s]
Building query seed array...  [2.842s]
Computing hash join...  [5.254s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [47.369s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.507s]
Building query seed array...  [2.195s]
Computing hash join...  [5.253s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [41.55s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.096s]
Building query seed array...  [2.026s]
Computing hash join...  [5.12s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [45.893s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.525s]
Building query seed array...  [2.413s]
Computing hash join...  [4.935s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [34.772s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.273s]
Building query seed array...  [2.529s]
Computing hash join...  [5.063s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [37.836s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.171s]
Building query seed array...  [2.042s]
Computing hash join...  [5.049s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [32.415s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.131s]
Clearing query masking...  [1.676s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.7s]
Sorting trace points...  [1.317s]
Computing alignments...  [34.039s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.055s]
Sorting trace points...  [0.988s]
Computing alignments...  [34.002s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.179s]
Sorting trace points...  [1.303s]
Computing alignments...  [34.217s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.06s]
Computing alignments...  [33.758s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.226s]
Computing alignments...  [33.547s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.061s]
Sorting trace points...  [0.965s]
Computing alignments...  [33.66s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.218s]
Computing alignments...  [34.002s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.04s]
Sorting trace points...  [1.138s]
Computing alignments...  [33.603s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.324s]
Computing alignments...  [35.302s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.392s]
Computing alignments...  [36.845s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.105s]
Sorting trace points...  [1.349s]
Computing alignments...  [36.612s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.044s]
Computing alignments...  [36.73s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.793s]
Sorting trace points...  [1.408s]
Computing alignments...  [36.853s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.356s]
Computing alignments...  [37.086s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.372s]
Computing alignments...  [36.876s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.375s]
Computing alignments...  [36.671s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [592.369s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [29.613s]
Masking reference...  [30.908s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.114s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.224s]
Building query seed array...  [2.258s]
Computing hash join...  [5.37s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [80.221s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.245s]
Building query seed array...  [2.623s]
Computing hash join...  [5.306s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [51.821s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.561s]
Building query seed array...  [2.84s]
Computing hash join...  [5.224s]
Masking low complexity seeds...  [0.272s]
Searching alignments...  [47.841s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.1s]
Building query seed array...  [2.231s]
Computing hash join...  [5.335s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [42.302s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.554s]
Building query seed array...  [2.054s]
Computing hash join...  [5.163s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [45.446s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.95s]
Building query seed array...  [2.369s]
Computing hash join...  [5.119s]
Masking low complexity seeds...  [0.256s]
Searching alignments...  [35.735s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.982s]
Building query seed array...  [2.573s]
Computing hash join...  [5.088s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [37.67s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.848s]
Building query seed array...  [2.06s]
Computing hash join...  [4.976s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [32.048s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.128s]
Clearing query masking...  [1.72s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.587s]
Sorting trace points...  [1.332s]
Computing alignments...  [34.029s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.262s]
Computing alignments...  [34.079s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.242s]
Computing alignments...  [34.299s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.072s]
Computing alignments...  [33.626s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.248s]
Computing alignments...  [33.496s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.039s]
Sorting trace points...  [1.195s]
Computing alignments...  [33.64s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.285s]
Computing alignments...  [34.047s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.088s]
Sorting trace points...  [1.248s]
Computing alignments...  [33.528s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.333s]
Computing alignments...  [35.255s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.398s]
Computing alignments...  [36.794s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.359s]
Computing alignments...  [36.599s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.388s]
Computing alignments...  [36.601s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.374s]
Computing alignments...  [36.63s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.328s]
Computing alignments...  [36.875s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.401s]
Computing alignments...  [36.66s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.373s]
Computing alignments...  [36.469s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [591.293s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [29.583s]
Masking reference...  [32.253s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.093s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.458s]
Building query seed array...  [2.221s]
Computing hash join...  [5.374s]
Masking low complexity seeds...  [0.267s]
Searching alignments...  [83.795s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.658s]
Building query seed array...  [2.647s]
Computing hash join...  [5.319s]
Masking low complexity seeds...  [0.259s]
Searching alignments...  [54.707s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.116s]
Building query seed array...  [2.783s]
Computing hash join...  [5.321s]
Masking low complexity seeds...  [0.266s]
Searching alignments...  [47.856s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.066s]
Building query seed array...  [2.207s]
Computing hash join...  [5.38s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [42.587s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.141s]
Building query seed array...  [1.98s]
Computing hash join...  [5.004s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [46.72s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.458s]
Building query seed array...  [2.389s]
Computing hash join...  [5.062s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [35.508s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.752s]
Building query seed array...  [2.527s]
Computing hash join...  [5.02s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [38.937s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.491s]
Building query seed array...  [2.095s]
Computing hash join...  [5.084s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [33.208s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.755s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.595s]
Sorting trace points...  [1.3s]
Computing alignments...  [33.898s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.152s]
Computing alignments...  [33.927s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.268s]
Computing alignments...  [34.174s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.284s]
Computing alignments...  [33.673s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.245s]
Computing alignments...  [33.385s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.246s]
Computing alignments...  [33.595s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.134s]
Computing alignments...  [33.956s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.243s]
Computing alignments...  [33.575s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.093s]
Computing alignments...  [35.285s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.206s]
Computing alignments...  [36.834s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.362s]
Computing alignments...  [36.725s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.002s]
Sorting trace points...  [1.424s]
Computing alignments...  [36.834s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.416s]
Computing alignments...  [36.916s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.391s]
Computing alignments...  [36.951s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.423s]
Computing alignments...  [36.815s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.336s]
Computing alignments...  [36.649s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [591.43s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [31.035s]
Masking reference...  [31.62s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.167s]
Allocating buffers...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.322s]
Building query seed array...  [2.318s]
Computing hash join...  [5.335s]
Masking low complexity seeds...  [0.266s]
Searching alignments...  [78.969s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.319s]
Building query seed array...  [2.605s]
Computing hash join...  [5.311s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [54.787s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.486s]
Building query seed array...  [2.811s]
Computing hash join...  [5.257s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [46.492s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.083s]
Building query seed array...  [2.184s]
Computing hash join...  [5.236s]
Masking low complexity seeds...  [0.266s]
Searching alignments...  [41.45s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.099s]
Building query seed array...  [2.028s]
Computing hash join...  [5.17s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [44.167s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.522s]
Building query seed array...  [2.378s]
Computing hash join...  [5.044s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [35.062s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.81s]
Building query seed array...  [2.478s]
Computing hash join...  [5.178s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [37.507s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.08s]
Building query seed array...  [2.007s]
Computing hash join...  [5.028s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [32.394s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.145s]
Clearing query masking...  [1.763s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.615s]
Sorting trace points...  [1.337s]
Computing alignments...  [33.891s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.2s]
Computing alignments...  [34.019s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.274s]
Computing alignments...  [34.237s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.048s]
Sorting trace points...  [0.992s]
Computing alignments...  [33.862s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.091s]
Sorting trace points...  [0.971s]
Computing alignments...  [33.522s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.043s]
Computing alignments...  [33.627s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.279s]
Computing alignments...  [33.964s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.284s]
Computing alignments...  [33.653s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.327s]
Computing alignments...  [35.364s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.301s]
Sorting trace points...  [1.411s]
Computing alignments...  [36.853s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.369s]
Computing alignments...  [36.674s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.381s]
Computing alignments...  [36.639s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.421s]
Computing alignments...  [36.732s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.398s]
Computing alignments...  [36.813s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.042s]
Sorting trace points...  [1.367s]
Computing alignments...  [36.801s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0s]
Sorting trace points...  [1.279s]
Computing alignments...  [36.584s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
 [591.615s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [30.057s]
Masking reference...  [31.238s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.744s]
Allocating buffers...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.304s]
Building query seed array...  [2.278s]
Computing hash join...  [5.421s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [81.104s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.415s]
Building query seed array...  [2.526s]
Computing hash join...  [5.308s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [52.474s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.779s]
Building query seed array...  [2.806s]
Computing hash join...  [5.311s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [46.169s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.124s]
Building query seed array...  [2.235s]
Computing hash join...  [5.309s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [41.086s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.238s]
Building query seed array...  [2.007s]
Computing hash join...  [5.049s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [45.834s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.104s]
Building query seed array...  [2.375s]
Computing hash join...  [5.048s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [34.288s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.492s]
Building query seed array...  [2.529s]
Computing hash join...  [5.02s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [37.737s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.697s]
Building query seed array...  [2.113s]
Computing hash join...  [5.022s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [32.267s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.122s]
Clearing query masking...  [1.693s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.653s]
Sorting trace points...  [1.333s]
Computing alignments...  [33.81s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.278s]
Computing alignments...  [33.935s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.288s]
Computing alignments...  [34.203s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.037s]
Sorting trace points...  [1.238s]
Computing alignments...  [33.584s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.119s]
Computing alignments...  [33.379s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.243s]
Computing alignments...  [33.569s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.248s]
Computing alignments...  [33.879s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.084s]
Sorting trace points...  [0.976s]
Computing alignments...  [33.51s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.038s]
Sorting trace points...  [1.133s]
Computing alignments...  [35.245s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.064s]
Computing alignments...  [36.741s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.22s]
Computing alignments...  [36.613s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.386s]
Computing alignments...  [36.649s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.109s]
Computing alignments...  [36.636s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.36s]
Computing alignments...  [36.853s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.038s]
Sorting trace points...  [1.188s]
Computing alignments...  [36.837s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.369s]
Computing alignments...  [36.631s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [589.525s]
Deallocating reference...  [0.063s]
Loading reference sequences...  [29.509s]
Masking reference...  [30.931s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.945s]
Allocating buffers...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.124s]
Building query seed array...  [2.305s]
Computing hash join...  [5.237s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [79.843s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.639s]
Building query seed array...  [2.698s]
Computing hash join...  [5.379s]
Masking low complexity seeds...  [0.267s]
Searching alignments...  [50.793s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.607s]
Building query seed array...  [2.693s]
Computing hash join...  [5.282s]
Masking low complexity seeds...  [0.259s]
Searching alignments...  [47.089s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.541s]
Building query seed array...  [2.195s]
Computing hash join...  [5.44s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [41.961s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.72s]
Building query seed array...  [2.124s]
Computing hash join...  [5.126s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [43.619s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.24s]
Building query seed array...  [2.418s]
Computing hash join...  [4.984s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [35.23s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.155s]
Building query seed array...  [2.574s]
Computing hash join...  [5.108s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [35.517s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.152s]
Building query seed array...  [2.085s]
Computing hash join...  [5.051s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [31.37s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.13s]
Clearing query masking...  [1.732s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.86s]
Sorting trace points...  [1.344s]
Computing alignments...  [33.618s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.25s]
Computing alignments...  [33.639s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.053s]
Sorting trace points...  [0.954s]
Computing alignments...  [33.898s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.249s]
Computing alignments...  [33.431s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.048s]
Sorting trace points...  [0.942s]
Computing alignments...  [33.12s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.233s]
Computing alignments...  [33.341s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.255s]
Computing alignments...  [33.748s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.275s]
Computing alignments...  [33.286s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.215s]
Computing alignments...  [35.081s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.446s]
Computing alignments...  [36.48s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.369s]
Computing alignments...  [36.406s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.273s]
Computing alignments...  [37.033s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.383s]
Computing alignments...  [36.481s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.378s]
Computing alignments...  [36.556s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.293s]
Computing alignments...  [36.473s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.349s]
Computing alignments...  [36.298s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [587.27s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.81s]
Masking reference...  [30.869s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [33.164s]
Allocating buffers...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [9.992s]
Building query seed array...  [2.24s]
Computing hash join...  [5.263s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [82.435s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.557s]
Building query seed array...  [2.573s]
Computing hash join...  [5.257s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [53.813s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.446s]
Building query seed array...  [2.689s]
Computing hash join...  [5.163s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [48.499s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.16s]
Building query seed array...  [2.23s]
Computing hash join...  [5.314s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [43.235s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.638s]
Building query seed array...  [2.009s]
Computing hash join...  [5.128s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [45.736s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.976s]
Building query seed array...  [2.349s]
Computing hash join...  [5.05s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [34.786s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.424s]
Building query seed array...  [2.457s]
Computing hash join...  [5.116s]
Masking low complexity seeds...  [0.249s]
Searching alignments...  [38.134s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.082s]
Building query seed array...  [1.994s]
Computing hash join...  [5.108s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [32.612s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.139s]
Clearing query masking...  [1.743s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.794s]
Sorting trace points...  [1.328s]
Computing alignments...  [33.937s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.297s]
Computing alignments...  [34.788s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.283s]
Computing alignments...  [34.149s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.062s]
Sorting trace points...  [0.912s]
Computing alignments...  [33.646s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.255s]
Computing alignments...  [33.401s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.2s]
Computing alignments...  [33.622s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.179s]
Computing alignments...  [33.945s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.238s]
Computing alignments...  [33.542s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.201s]
Sorting trace points...  [1.363s]
Computing alignments...  [35.234s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.133s]
Sorting trace points...  [1.404s]
Computing alignments...  [36.731s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.051s]
Computing alignments...  [36.693s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.249s]
Computing alignments...  [36.62s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.038s]
Sorting trace points...  [1.392s]
Computing alignments...  [36.746s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.384s]
Computing alignments...  [36.806s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.405s]
Computing alignments...  [36.718s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.141s]
Computing alignments...  [36.443s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
 [591.201s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.658s]
Masking reference...  [32.064s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.77s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.159s]
Building query seed array...  [2.236s]
Computing hash join...  [5.343s]
Masking low complexity seeds...  [0.27s]
Searching alignments...  [81.993s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.924s]
Building query seed array...  [2.599s]
Computing hash join...  [5.267s]
Masking low complexity seeds...  [0.259s]
Searching alignments...  [54.001s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.474s]
Building query seed array...  [2.772s]
Computing hash join...  [5.268s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [48.427s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.496s]
Building query seed array...  [2.18s]
Computing hash join...  [5.305s]
Masking low complexity seeds...  [0.256s]
Searching alignments...  [41.731s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.04s]
Building query seed array...  [2.145s]
Computing hash join...  [5.104s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [43.794s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.768s]
Building query seed array...  [2.359s]
Computing hash join...  [5s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [34.26s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.433s]
Building query seed array...  [2.432s]
Computing hash join...  [4.95s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [37.329s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.187s]
Building query seed array...  [2.063s]
Computing hash join...  [5.039s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [32.141s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.65s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.534s]
Sorting trace points...  [1.341s]
Computing alignments...  [33.815s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.316s]
Computing alignments...  [33.82s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.107s]
Sorting trace points...  [1.293s]
Computing alignments...  [34.03s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.32s]
Computing alignments...  [33.541s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.084s]
Sorting trace points...  [1.242s]
Computing alignments...  [33.261s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.276s]
Computing alignments...  [33.52s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.088s]
Sorting trace points...  [1.3s]
Computing alignments...  [33.827s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.282s]
Computing alignments...  [33.457s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.055s]
Sorting trace points...  [0.985s]
Computing alignments...  [35.177s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.401s]
Computing alignments...  [36.576s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.119s]
Computing alignments...  [36.504s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.434s]
Computing alignments...  [36.565s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.383s]
Computing alignments...  [36.631s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.375s]
Computing alignments...  [36.754s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.347s]
Computing alignments...  [36.765s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0s]
Sorting trace points...  [1.403s]
Computing alignments...  [36.517s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [589.376s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [31.434s]
Masking reference...  [30.953s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [33.202s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.426s]
Building query seed array...  [2.293s]
Computing hash join...  [5.217s]
Masking low complexity seeds...  [0.256s]
Searching alignments...  [82.013s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.843s]
Building query seed array...  [2.591s]
Computing hash join...  [5.322s]
Masking low complexity seeds...  [0.273s]
Searching alignments...  [53.331s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.516s]
Building query seed array...  [2.723s]
Computing hash join...  [5.269s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [46.56s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.819s]
Building query seed array...  [2.283s]
Computing hash join...  [5.347s]
Masking low complexity seeds...  [0.276s]
Searching alignments...  [41.276s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.217s]
Building query seed array...  [2.026s]
Computing hash join...  [5.008s]
Masking low complexity seeds...  [0.249s]
Searching alignments...  [44.505s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.843s]
Building query seed array...  [2.392s]
Computing hash join...  [4.914s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [34.482s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.749s]
Building query seed array...  [2.524s]
Computing hash join...  [5.029s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [37.265s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.074s]
Building query seed array...  [2.01s]
Computing hash join...  [5.099s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [32.113s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.719s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.702s]
Sorting trace points...  [1.316s]
Computing alignments...  [33.891s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.187s]
Computing alignments...  [33.923s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.192s]
Sorting trace points...  [1.253s]
Computing alignments...  [34.043s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.042s]
Sorting trace points...  [1.211s]
Computing alignments...  [33.618s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.254s]
Computing alignments...  [33.241s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.279s]
Computing alignments...  [33.473s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.255s]
Computing alignments...  [33.824s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.24s]
Computing alignments...  [33.548s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.038s]
Sorting trace points...  [1.371s]
Computing alignments...  [35.215s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.133s]
Computing alignments...  [36.75s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.347s]
Computing alignments...  [36.999s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.08s]
Computing alignments...  [36.537s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.414s]
Computing alignments...  [36.581s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.374s]
Computing alignments...  [36.741s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.032s]
Computing alignments...  [36.672s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.373s]
Computing alignments...  [36.45s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [589.603s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.484s]
Masking reference...  [31.958s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.893s]
Allocating buffers...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.695s]
Building query seed array...  [2.293s]
Computing hash join...  [5.201s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [81.891s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.305s]
Building query seed array...  [2.723s]
Computing hash join...  [5.245s]
Masking low complexity seeds...  [0.259s]
Searching alignments...  [52.955s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.581s]
Building query seed array...  [2.757s]
Computing hash join...  [5.141s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [48.381s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.322s]
Building query seed array...  [2.198s]
Computing hash join...  [5.225s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [43.17s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.019s]
Building query seed array...  [2.008s]
Computing hash join...  [5.131s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [46.651s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.242s]
Building query seed array...  [2.329s]
Computing hash join...  [4.939s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [36.035s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.818s]
Building query seed array...  [2.459s]
Computing hash join...  [5.074s]
Masking low complexity seeds...  [0.259s]
Searching alignments...  [38.922s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.832s]
Building query seed array...  [2.105s]
Computing hash join...  [5.045s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [32.984s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.704s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.613s]
Sorting trace points...  [1.346s]
Computing alignments...  [33.766s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.238s]
Computing alignments...  [33.877s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.291s]
Computing alignments...  [34.063s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.237s]
Computing alignments...  [33.592s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.252s]
Computing alignments...  [33.255s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.287s]
Computing alignments...  [33.474s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.052s]
Sorting trace points...  [0.945s]
Computing alignments...  [33.845s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.264s]
Computing alignments...  [33.413s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.211s]
Computing alignments...  [35.155s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.357s]
Computing alignments...  [36.6s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.406s]
Computing alignments...  [36.995s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.37s]
Computing alignments...  [36.554s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.002s]
Sorting trace points...  [1.25s]
Computing alignments...  [36.574s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.122s]
Sorting trace points...  [1.389s]
Computing alignments...  [36.732s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.168s]
Sorting trace points...  [1.039s]
Computing alignments...  [36.649s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.396s]
Computing alignments...  [36.364s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
 [589.172s]
Deallocating reference...  [0.072s]
Loading reference sequences...  [34.614s]
Masking reference...  [31.439s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.569s]
Building reference histograms...  [32.792s]
Allocating buffers...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.321s]
Building query seed array...  [2.28s]
Computing hash join...  [5.254s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [79.273s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.565s]
Building query seed array...  [2.666s]
Computing hash join...  [5.207s]
Masking low complexity seeds...  [0.256s]
Searching alignments...  [52.706s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.336s]
Building query seed array...  [2.818s]
Computing hash join...  [5.312s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [47.258s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.17s]
Building query seed array...  [2.232s]
Computing hash join...  [5.218s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [41.939s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.205s]
Building query seed array...  [2.022s]
Computing hash join...  [5.03s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [43.456s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.096s]
Building query seed array...  [2.337s]
Computing hash join...  [5.074s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [35.023s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.636s]
Building query seed array...  [2.489s]
Computing hash join...  [5.117s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [39.122s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.096s]
Building query seed array...  [1.946s]
Computing hash join...  [5.009s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [32.256s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.135s]
Clearing query masking...  [1.761s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.967s]
Sorting trace points...  [1.356s]
Computing alignments...  [33.719s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.311s]
Computing alignments...  [33.826s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.118s]
Computing alignments...  [33.895s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.291s]
Computing alignments...  [33.404s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.251s]
Computing alignments...  [33.08s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.171s]
Computing alignments...  [33.438s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.302s]
Computing alignments...  [33.713s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.24s]
Computing alignments...  [33.378s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.281s]
Computing alignments...  [35.168s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.094s]
Sorting trace points...  [1.4s]
Computing alignments...  [36.576s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.092s]
Sorting trace points...  [1.377s]
Computing alignments...  [36.477s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.14s]
Sorting trace points...  [1.392s]
Computing alignments...  [36.478s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.4s]
Computing alignments...  [36.576s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.301s]
Computing alignments...  [36.7s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.349s]
Computing alignments...  [36.547s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
Sorting trace points...  [1.395s]
Computing alignments...  [36.34s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [588.488s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [32.892s]
Masking reference...  [32.183s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [31.99s]
Allocating buffers...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.12s]
Building query seed array...  [2.277s]
Computing hash join...  [5.259s]
Masking low complexity seeds...  [0.268s]
Searching alignments...  [82.784s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.602s]
Building query seed array...  [2.611s]
Computing hash join...  [5.379s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [53.611s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [12.89s]
Building query seed array...  [2.755s]
Computing hash join...  [5.143s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [46.784s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.375s]
Building query seed array...  [2.254s]
Computing hash join...  [5.314s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [41.359s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.83s]
Building query seed array...  [2.116s]
Computing hash join...  [5.036s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [45.45s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.516s]
Building query seed array...  [2.381s]
Computing hash join...  [5.1s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [34.396s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.981s]
Building query seed array...  [2.519s]
Computing hash join...  [5.052s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [38.096s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.95s]
Building query seed array...  [2.055s]
Computing hash join...  [5.007s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [32.265s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.153s]
Clearing query masking...  [1.78s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.826s]
Sorting trace points...  [1.328s]
Computing alignments...  [33.913s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.262s]
Computing alignments...  [33.973s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.21s]
Computing alignments...  [34.189s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.266s]
Computing alignments...  [33.632s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.187s]
Computing alignments...  [33.394s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.022s]
Computing alignments...  [33.694s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.291s]
Computing alignments...  [34.025s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.238s]
Computing alignments...  [33.663s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.292s]
Computing alignments...  [35.3s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.362s]
Sorting trace points...  [1.43s]
Computing alignments...  [36.705s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.1s]
Sorting trace points...  [1.044s]
Computing alignments...  [36.586s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.353s]
Computing alignments...  [36.63s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.213s]
Sorting trace points...  [1.403s]
Computing alignments...  [36.786s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.374s]
Computing alignments...  [36.782s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.042s]
Sorting trace points...  [1.375s]
Computing alignments...  [36.7s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.13s]
Computing alignments...  [36.427s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
 [591.169s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [34.484s]
Masking reference...  [30.885s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.436s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.24s]
Building query seed array...  [2.182s]
Computing hash join...  [5.219s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [83.764s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.358s]
Building query seed array...  [2.612s]
Computing hash join...  [5.256s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [53.096s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.758s]
Building query seed array...  [2.748s]
Computing hash join...  [5.265s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [48.375s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.136s]
Building query seed array...  [2.238s]
Computing hash join...  [5.21s]
Masking low complexity seeds...  [0.268s]
Searching alignments...  [43.738s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.029s]
Building query seed array...  [2.027s]
Computing hash join...  [5.07s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [45.903s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.912s]
Building query seed array...  [2.294s]
Computing hash join...  [5.035s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [35.503s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.03s]
Building query seed array...  [2.442s]
Computing hash join...  [5.123s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [38.395s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.913s]
Building query seed array...  [1.976s]
Computing hash join...  [4.926s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [32.58s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.136s]
Clearing query masking...  [1.781s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.823s]
Sorting trace points...  [1.33s]
Computing alignments...  [33.477s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.04s]
Sorting trace points...  [1.228s]
Computing alignments...  [33.659s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.266s]
Computing alignments...  [33.898s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.066s]
Sorting trace points...  [0.994s]
Computing alignments...  [33.432s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.208s]
Computing alignments...  [33.08s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.109s]
Sorting trace points...  [1.232s]
Computing alignments...  [33.293s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.276s]
Computing alignments...  [33.766s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.271s]
Computing alignments...  [33.344s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.346s]
Computing alignments...  [35.083s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.377s]
Computing alignments...  [36.595s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.245s]
Computing alignments...  [36.442s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.052s]
Computing alignments...  [36.477s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.036s]
Computing alignments...  [36.476s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.376s]
Computing alignments...  [36.552s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.21s]
Computing alignments...  [36.52s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.293s]
Computing alignments...  [36.369s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [586.351s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [24.412s]
Masking reference...  [25.174s]
Initializing dictionary...  [0.063s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [26.933s]
Allocating buffers...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.642s]
Building query seed array...  [2.273s]
Computing hash join...  [4.449s]
Masking low complexity seeds...  [0.256s]
Searching alignments...  [65.444s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [10.275s]
Building query seed array...  [2.576s]
Computing hash join...  [4.411s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [43.378s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [10.478s]
Building query seed array...  [2.725s]
Computing hash join...  [4.362s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [38.623s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [8.284s]
Building query seed array...  [2.225s]
Computing hash join...  [4.329s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [34.855s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [7.847s]
Building query seed array...  [2.008s]
Computing hash join...  [4.178s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [37.451s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [9.823s]
Building query seed array...  [2.389s]
Computing hash join...  [4.239s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [28.608s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [10.924s]
Building query seed array...  [2.515s]
Computing hash join...  [4.179s]
Masking low complexity seeds...  [0.259s]
Searching alignments...  [29.878s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [7.831s]
Building query seed array...  [2.036s]
Computing hash join...  [4.182s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [27.232s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.11s]
Clearing query masking...  [1.7s]
Opening temporary output file...  [0.016s]
Computing alignments... Loading trace points...  [11.165s]
Sorting trace points...  [2.163s]
Computing alignments...  [53.597s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.131s]
Sorting trace points...  [1.69s]
Computing alignments...  [53.739s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0.127s]
Sorting trace points...  [2.138s]
Computing alignments...  [53.259s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.89s]
Computing alignments...  [53.506s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.106s]
Computing alignments...  [28.086s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.033s]
Sorting trace points...  [1.104s]
Computing alignments...  [29.202s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.107s]
Computing alignments...  [29.128s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.115s]
Computing alignments...  [29.186s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.037s]
Computing alignments...  [29.213s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.037s]
Sorting trace points...  [1.137s]
Computing alignments...  [29.373s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.097s]
Computing alignments...  [29.265s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0s]
Sorting trace points...  [1.074s]
Computing alignments...  [29.01s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
 [475.438s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [0.117s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [2105.53s]
 [2105.53s]
Deallocating queries...  [0.06s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [3.778s]
 [4.847s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 19037.8s
Reported 2646816166 pairwise alignments, 2646816166 HSPs.
14773001 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C30_R2.fastp-trim.20230215.fq.gz complete: C30_R2.blastx.meganized.daa

Now MEGANizing C30_R2.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: C30_R2.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 100% (245.9s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.2s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (4,994.3s)
Total reads:       14,773,001
With hits:          14,773,001 
Alignments:      2,642,772,326
Assig. Taxonomy:    13,782,001
Assig. SEED:           123,623
Assig. EGGNOG:          67,005
Assig. GTDB:           458,853
Assig. EC:           2,548,189
Assig. INTERPRO2GO:  1,382,211
MinSupport set to: 7386
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.4s)
Min-supp. changes:       4,386
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (13.8s)
Min-supp. changes:       3,524
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (53.9s)
Binning reads Syncing
100% (0.4s)
Class. Taxonomy:            68
Class. SEED:               519
Class. EGGNOG:           1,842
Class. GTDB:                18
Class. EC:               2,391
Class. INTERPRO2GO:      7,948
Total time:  5,318s
Peak memory: 28.9 of 195.3G
MEGANization of C30_R2.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C31_R1.fastp-trim.20230215.fq.gz...
7123a2d9e5431d71ccf88c0cf19b1588  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C31_R1.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C31_R1.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.333s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.727s]
Opening the output file...  [0s]
Loading query sequences...  [75.284s]
Masking queries...  [19.137s]
Algorithm: Double-indexed
Building query histograms...  [19.335s]
Loading reference sequences...  [29.32s]
Masking reference...  [32.119s]
Initializing dictionary...  [0.08s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.488s]
Allocating buffers...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.275s]
Building query seed array...  [2.081s]
Computing hash join...  [5.257s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [78.671s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.171s]
Building query seed array...  [2.435s]
Computing hash join...  [5.177s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [51.511s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.441s]
Building query seed array...  [2.66s]
Computing hash join...  [5.031s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [45.415s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.351s]
Building query seed array...  [2.093s]
Computing hash join...  [5.123s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [40.35s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.156s]
Building query seed array...  [1.9s]
Computing hash join...  [4.967s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [40.317s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.066s]
Building query seed array...  [2.203s]
Computing hash join...  [4.906s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [32.355s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.315s]
Building query seed array...  [2.337s]
Computing hash join...  [4.956s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [34.924s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.854s]
Building query seed array...  [1.936s]
Computing hash join...  [4.825s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [32.223s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.646s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.334s]
Sorting trace points...  [1.246s]
Computing alignments...  [32.015s]
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Sorting trace points...  [1.203s]
Computing alignments...  [32.136s]
Deallocating buffers...  [0.019s]
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Computing alignments...  [32.043s]
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Computing alignments...  [31.879s]
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Computing alignments...  [31.306s]
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Sorting trace points...  [0.922s]
Computing alignments...  [31.578s]
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Sorting trace points...  [1.233s]
Computing alignments...  [31.908s]
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Computing alignments...  [31.55s]
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Computing alignments...  [32.498s]
Deallocating buffers...  [0.018s]
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Computing alignments...  [33.437s]
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Computing alignments...  [33.405s]
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Computing alignments...  [33.274s]
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Computing alignments...  [33.82s]
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Computing alignments...  [33.585s]
Deallocating buffers...  [0.015s]
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Sorting trace points...  [1.291s]
Computing alignments...  [33.641s]
Deallocating buffers...  [0.021s]
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Computing alignments...  [33.136s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [547.709s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [29.567s]
Masking reference...  [32.201s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [31.722s]
Allocating buffers...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [9.888s]
Building query seed array...  [2.123s]
Computing hash join...  [5.223s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [78.117s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.966s]
Building query seed array...  [2.467s]
Computing hash join...  [5.101s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [50.902s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.737s]
Building query seed array...  [2.652s]
Computing hash join...  [5.009s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [43.294s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.005s]
Building query seed array...  [2.107s]
Computing hash join...  [5.125s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [37.55s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.906s]
Building query seed array...  [1.903s]
Computing hash join...  [4.91s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [39.955s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.99s]
Building query seed array...  [2.23s]
Computing hash join...  [4.872s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [31.741s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.984s]
Building query seed array...  [2.344s]
Computing hash join...  [4.971s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [35.147s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.119s]
Building query seed array...  [1.926s]
Computing hash join...  [4.871s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [30.306s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.137s]
Clearing query masking...  [1.658s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.321s]
Sorting trace points...  [1.278s]
Computing alignments...  [31.692s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.178s]
Computing alignments...  [31.842s]
Deallocating buffers...  [0.017s]
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Sorting trace points...  [1.207s]
Computing alignments...  [31.868s]
Deallocating buffers...  [0.018s]
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Sorting trace points...  [1.199s]
Computing alignments...  [31.685s]
Deallocating buffers...  [0.017s]
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Sorting trace points...  [1.177s]
Computing alignments...  [31.146s]
Deallocating buffers...  [0.02s]
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Sorting trace points...  [1.25s]
Computing alignments...  [31.369s]
Deallocating buffers...  [0.014s]
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Sorting trace points...  [1.223s]
Computing alignments...  [31.762s]
Deallocating buffers...  [0.014s]
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Sorting trace points...  [0.907s]
Computing alignments...  [31.382s]
Deallocating buffers...  [0.021s]
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Sorting trace points...  [1.241s]
Computing alignments...  [32.244s]
Deallocating buffers...  [0.018s]
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Sorting trace points...  [1.297s]
Computing alignments...  [33.299s]
Deallocating buffers...  [0.015s]
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Sorting trace points...  [1.049s]
Computing alignments...  [33.205s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.246s]
Computing alignments...  [33.112s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.335s]
Computing alignments...  [33.574s]
Deallocating buffers...  [0.022s]
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Sorting trace points...  [1.269s]
Computing alignments...  [33.367s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.275s]
Computing alignments...  [33.538s]
Deallocating buffers...  [0.021s]
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Sorting trace points...  [1.182s]
Computing alignments...  [32.979s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [545.836s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [29.588s]
Masking reference...  [32.226s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.152s]
Allocating buffers...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.129s]
Building query seed array...  [2.117s]
Computing hash join...  [5.144s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [79.043s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.371s]
Building query seed array...  [2.42s]
Computing hash join...  [5.162s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [51.339s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.445s]
Building query seed array...  [2.653s]
Computing hash join...  [5.16s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [43.668s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.273s]
Building query seed array...  [2.044s]
Computing hash join...  [5.067s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [38.995s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.363s]
Building query seed array...  [1.895s]
Computing hash join...  [4.927s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [39.619s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.452s]
Building query seed array...  [2.252s]
Computing hash join...  [4.952s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [32.084s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.221s]
Building query seed array...  [2.358s]
Computing hash join...  [4.947s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [35.808s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.948s]
Building query seed array...  [1.915s]
Computing hash join...  [4.974s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [30.266s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.641s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.412s]
Sorting trace points...  [1.266s]
Computing alignments...  [31.672s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.101s]
Sorting trace points...  [1.207s]
Computing alignments...  [31.805s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.233s]
Computing alignments...  [31.885s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.206s]
Computing alignments...  [31.669s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.04s]
Sorting trace points...  [1.187s]
Computing alignments...  [31.17s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.2s]
Computing alignments...  [31.399s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.219s]
Computing alignments...  [31.816s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.189s]
Computing alignments...  [31.364s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.097s]
Computing alignments...  [32.244s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.281s]
Computing alignments...  [33.234s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.266s]
Computing alignments...  [33.193s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.255s]
Computing alignments...  [33.082s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.256s]
Computing alignments...  [33.556s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.305s]
Computing alignments...  [33.38s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.08s]
Computing alignments...  [33.421s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
Sorting trace points...  [1.258s]
Computing alignments...  [32.843s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [544.816s]
Deallocating reference...  [0.063s]
Loading reference sequences...  [29.481s]
Masking reference...  [30.9s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.707s]
Allocating buffers...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.464s]
Building query seed array...  [2.1s]
Computing hash join...  [5.128s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [79.262s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.483s]
Building query seed array...  [2.477s]
Computing hash join...  [5.109s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [49.284s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.725s]
Building query seed array...  [2.667s]
Computing hash join...  [5.15s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [43.304s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.357s]
Building query seed array...  [2.181s]
Computing hash join...  [5.082s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [38.353s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.153s]
Building query seed array...  [1.941s]
Computing hash join...  [4.872s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [39.545s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.354s]
Building query seed array...  [2.216s]
Computing hash join...  [4.948s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [31.339s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.227s]
Building query seed array...  [2.326s]
Computing hash join...  [4.916s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [35.969s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.957s]
Building query seed array...  [1.977s]
Computing hash join...  [4.849s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [29.92s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.134s]
Clearing query masking...  [1.63s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.253s]
Sorting trace points...  [1.264s]
Computing alignments...  [31.881s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.173s]
Computing alignments...  [31.97s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.216s]
Computing alignments...  [32.191s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.199s]
Computing alignments...  [31.794s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.204s]
Computing alignments...  [31.183s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.11s]
Computing alignments...  [31.459s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.172s]
Computing alignments...  [31.839s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.182s]
Computing alignments...  [31.38s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.101s]
Sorting trace points...  [1.235s]
Computing alignments...  [32.271s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.317s]
Computing alignments...  [33.371s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.281s]
Computing alignments...  [33.365s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.288s]
Computing alignments...  [33.19s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.261s]
Computing alignments...  [33.864s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.103s]
Sorting trace points...  [1.279s]
Computing alignments...  [33.56s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.257s]
Computing alignments...  [33.575s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [1.22s]
Computing alignments...  [33.024s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [546.995s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.845s]
Masking reference...  [32.074s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [33.298s]
Allocating buffers...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.639s]
Building query seed array...  [2.156s]
Computing hash join...  [5.081s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [79.6s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.737s]
Building query seed array...  [2.433s]
Computing hash join...  [5.115s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [49.49s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.692s]
Building query seed array...  [2.595s]
Computing hash join...  [5.007s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [43.32s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.547s]
Building query seed array...  [2.089s]
Computing hash join...  [5.081s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [38.003s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.362s]
Building query seed array...  [1.959s]
Computing hash join...  [4.959s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [39.184s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.981s]
Building query seed array...  [2.267s]
Computing hash join...  [4.819s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [31.367s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.537s]
Building query seed array...  [2.412s]
Computing hash join...  [4.796s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [35.576s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.788s]
Building query seed array...  [2.014s]
Computing hash join...  [4.861s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [30.161s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.603s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.26s]
Sorting trace points...  [1.239s]
Computing alignments...  [31.571s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.899s]
Sorting trace points...  [1.225s]
Computing alignments...  [31.661s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.039s]
Sorting trace points...  [1.212s]
Computing alignments...  [31.937s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.201s]
Computing alignments...  [31.585s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [0.908s]
Computing alignments...  [31.298s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.184s]
Computing alignments...  [31.399s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.056s]
Sorting trace points...  [0.893s]
Computing alignments...  [31.823s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.186s]
Computing alignments...  [31.315s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.285s]
Computing alignments...  [32.155s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.047s]
Sorting trace points...  [0.941s]
Computing alignments...  [33.17s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.265s]
Computing alignments...  [33.102s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.061s]
Sorting trace points...  [0.996s]
Computing alignments...  [32.93s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.269s]
Computing alignments...  [33.495s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.094s]
Sorting trace points...  [1.27s]
Computing alignments...  [33.216s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.283s]
Computing alignments...  [33.345s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
Sorting trace points...  [1.168s]
Computing alignments...  [32.938s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
 [543.778s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [29.507s]
Masking reference...  [30.844s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.248s]
Allocating buffers...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [9.922s]
Building query seed array...  [2.151s]
Computing hash join...  [5.092s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [77.182s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.295s]
Building query seed array...  [2.486s]
Computing hash join...  [5.262s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [49.313s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.232s]
Building query seed array...  [2.614s]
Computing hash join...  [5.102s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [42.801s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.342s]
Building query seed array...  [2.127s]
Computing hash join...  [5.081s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [37.412s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.08s]
Building query seed array...  [1.964s]
Computing hash join...  [4.935s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [38.466s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.741s]
Building query seed array...  [2.187s]
Computing hash join...  [4.879s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [31.721s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.07s]
Building query seed array...  [2.376s]
Computing hash join...  [4.912s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [35.13s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.966s]
Building query seed array...  [1.901s]
Computing hash join...  [4.83s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [29.783s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.634s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.477s]
Sorting trace points...  [1.293s]
Computing alignments...  [31.357s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.203s]
Computing alignments...  [31.573s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.07s]
Sorting trace points...  [0.942s]
Computing alignments...  [31.605s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.201s]
Computing alignments...  [31.449s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.172s]
Computing alignments...  [30.892s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.756s]
Sorting trace points...  [1.178s]
Computing alignments...  [31.148s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.227s]
Computing alignments...  [31.493s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.233s]
Computing alignments...  [31.046s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.057s]
Sorting trace points...  [0.981s]
Computing alignments...  [31.939s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.312s]
Computing alignments...  [33.061s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.286s]
Computing alignments...  [32.989s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.044s]
Computing alignments...  [32.887s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.294s]
Computing alignments...  [33.444s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.003s]
Computing alignments...  [33.311s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.118s]
Computing alignments...  [33.586s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [1.304s]
Computing alignments...  [33.033s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
 [541.919s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.303s]
Masking reference...  [30.852s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.815s]
Allocating buffers...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.399s]
Building query seed array...  [2.112s]
Computing hash join...  [5.162s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [80.339s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.094s]
Building query seed array...  [2.53s]
Computing hash join...  [5.148s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [50.79s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.691s]
Building query seed array...  [2.622s]
Computing hash join...  [5.16s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [46.661s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.919s]
Building query seed array...  [2.127s]
Computing hash join...  [5.214s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [38.973s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.769s]
Building query seed array...  [1.917s]
Computing hash join...  [4.88s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [40.333s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.442s]
Building query seed array...  [2.212s]
Computing hash join...  [4.988s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [31.401s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.926s]
Building query seed array...  [2.385s]
Computing hash join...  [4.889s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [36.533s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.117s]
Building query seed array...  [1.943s]
Computing hash join...  [4.868s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [31.001s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.611s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.476s]
Sorting trace points...  [1.276s]
Computing alignments...  [31.709s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.252s]
Computing alignments...  [31.702s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.041s]
Sorting trace points...  [0.991s]
Computing alignments...  [31.855s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.217s]
Computing alignments...  [31.641s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.185s]
Computing alignments...  [31.229s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.203s]
Computing alignments...  [31.474s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.062s]
Sorting trace points...  [0.913s]
Computing alignments...  [31.729s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.077s]
Computing alignments...  [31.269s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.129s]
Sorting trace points...  [1.265s]
Computing alignments...  [32.182s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.278s]
Computing alignments...  [33.301s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.062s]
Computing alignments...  [33.199s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.041s]
Sorting trace points...  [0.973s]
Computing alignments...  [33.07s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.044s]
Sorting trace points...  [0.959s]
Computing alignments...  [33.641s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.164s]
Computing alignments...  [33.46s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.085s]
Sorting trace points...  [1.291s]
Computing alignments...  [33.532s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [1.19s]
Computing alignments...  [32.941s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [543.824s]
Deallocating reference...  [0.064s]
Loading reference sequences...  [29.627s]
Masking reference...  [30.86s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.398s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.358s]
Building query seed array...  [2.163s]
Computing hash join...  [5.078s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [79.138s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.773s]
Building query seed array...  [2.397s]
Computing hash join...  [5.08s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [49.864s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.744s]
Building query seed array...  [2.678s]
Computing hash join...  [5.034s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [44.349s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.339s]
Building query seed array...  [2.06s]
Computing hash join...  [4.977s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [38.972s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.044s]
Building query seed array...  [1.835s]
Computing hash join...  [4.951s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [40.003s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.097s]
Building query seed array...  [2.213s]
Computing hash join...  [4.857s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [31.836s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.191s]
Building query seed array...  [2.483s]
Computing hash join...  [4.861s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [35.219s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.344s]
Building query seed array...  [1.9s]
Computing hash join...  [4.929s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [30.048s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.137s]
Clearing query masking...  [1.678s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.25s]
Sorting trace points...  [1.3s]
Computing alignments...  [31.624s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.212s]
Computing alignments...  [31.868s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.233s]
Computing alignments...  [31.908s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.228s]
Computing alignments...  [31.524s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.082s]
Computing alignments...  [31.065s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.117s]
Computing alignments...  [31.305s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.198s]
Computing alignments...  [31.781s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.176s]
Computing alignments...  [31.285s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.069s]
Computing alignments...  [32.179s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.045s]
Sorting trace points...  [0.977s]
Computing alignments...  [33.227s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.263s]
Computing alignments...  [33.077s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.087s]
Sorting trace points...  [1.329s]
Computing alignments...  [33.027s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.31s]
Computing alignments...  [33.494s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.329s]
Computing alignments...  [33.319s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.041s]
Computing alignments...  [33.383s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
Sorting trace points...  [1.264s]
Computing alignments...  [32.904s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [543.494s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.531s]
Masking reference...  [32.108s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.754s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.555s]
Building query seed array...  [2.126s]
Computing hash join...  [5.099s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [79.033s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.275s]
Building query seed array...  [2.473s]
Computing hash join...  [5.069s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [50.798s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.26s]
Building query seed array...  [2.738s]
Computing hash join...  [5.195s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [43.949s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.016s]
Building query seed array...  [2.134s]
Computing hash join...  [5.034s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [38.984s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.994s]
Building query seed array...  [1.949s]
Computing hash join...  [4.868s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [39.776s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.415s]
Building query seed array...  [2.184s]
Computing hash join...  [4.793s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [31.449s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.599s]
Building query seed array...  [2.35s]
Computing hash join...  [4.924s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [35.686s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.067s]
Building query seed array...  [2.026s]
Computing hash join...  [4.845s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [30.352s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.122s]
Clearing query masking...  [1.551s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.371s]
Sorting trace points...  [1.293s]
Computing alignments...  [31.651s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.126s]
Computing alignments...  [31.781s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.055s]
Sorting trace points...  [0.938s]
Computing alignments...  [31.948s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.081s]
Sorting trace points...  [0.905s]
Computing alignments...  [31.654s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.084s]
Sorting trace points...  [0.899s]
Computing alignments...  [31.238s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.107s]
Computing alignments...  [31.536s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.043s]
Computing alignments...  [31.853s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.09s]
Sorting trace points...  [1.208s]
Computing alignments...  [31.344s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.174s]
Computing alignments...  [32.23s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.089s]
Sorting trace points...  [1.276s]
Computing alignments...  [33.237s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.034s]
Sorting trace points...  [0.94s]
Computing alignments...  [33.204s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.261s]
Computing alignments...  [33.153s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.284s]
Computing alignments...  [33.625s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.304s]
Computing alignments...  [33.507s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.051s]
Sorting trace points...  [0.944s]
Computing alignments...  [33.608s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
Sorting trace points...  [1.27s]
Computing alignments...  [33.074s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [544.303s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [31.903s]
Masking reference...  [30.852s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.824s]
Allocating buffers...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.607s]
Building query seed array...  [2.111s]
Computing hash join...  [5.093s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [80.257s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.74s]
Building query seed array...  [2.47s]
Computing hash join...  [5.216s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [50.645s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.58s]
Building query seed array...  [2.694s]
Computing hash join...  [5.077s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [43.78s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.156s]
Building query seed array...  [2.115s]
Computing hash join...  [5.052s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [39.102s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.047s]
Building query seed array...  [1.897s]
Computing hash join...  [4.853s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [39.762s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.13s]
Building query seed array...  [2.232s]
Computing hash join...  [4.847s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [31.586s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.539s]
Building query seed array...  [2.364s]
Computing hash join...  [5.103s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [35.984s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.91s]
Building query seed array...  [1.895s]
Computing hash join...  [4.903s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [31.515s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.14s]
Clearing query masking...  [1.599s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.37s]
Sorting trace points...  [1.274s]
Computing alignments...  [31.558s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.058s]
Computing alignments...  [31.846s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.048s]
Sorting trace points...  [0.999s]
Computing alignments...  [31.778s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.214s]
Computing alignments...  [31.536s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.177s]
Computing alignments...  [31.057s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.053s]
Sorting trace points...  [0.932s]
Computing alignments...  [31.357s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.184s]
Computing alignments...  [31.672s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.16s]
Computing alignments...  [31.169s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.191s]
Computing alignments...  [32.125s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.321s]
Computing alignments...  [33.125s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.126s]
Sorting trace points...  [1.012s]
Computing alignments...  [33.032s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.299s]
Computing alignments...  [32.946s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.276s]
Computing alignments...  [33.455s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.03s]
Computing alignments...  [33.264s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.173s]
Computing alignments...  [33.441s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
Sorting trace points...  [1.079s]
Computing alignments...  [32.815s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [542.189s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [29.817s]
Masking reference...  [32.124s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.185s]
Allocating buffers...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.366s]
Building query seed array...  [2.137s]
Computing hash join...  [5.128s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [78.036s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.198s]
Building query seed array...  [2.554s]
Computing hash join...  [5.009s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [48.602s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [12.937s]
Building query seed array...  [2.62s]
Computing hash join...  [5.057s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [43.007s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.333s]
Building query seed array...  [2.048s]
Computing hash join...  [5.103s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [38.034s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.214s]
Building query seed array...  [1.936s]
Computing hash join...  [4.978s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [38.379s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.977s]
Building query seed array...  [2.254s]
Computing hash join...  [4.889s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [30.955s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.351s]
Building query seed array...  [2.331s]
Computing hash join...  [4.923s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [34.821s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.928s]
Building query seed array...  [1.936s]
Computing hash join...  [4.926s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [29.607s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.567s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.351s]
Sorting trace points...  [1.251s]
Computing alignments...  [31.512s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.217s]
Computing alignments...  [31.668s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.122s]
Computing alignments...  [31.654s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.715s]
Sorting trace points...  [1.191s]
Computing alignments...  [31.426s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.138s]
Computing alignments...  [30.943s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.165s]
Computing alignments...  [31.179s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.09s]
Sorting trace points...  [1.211s]
Computing alignments...  [31.605s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.212s]
Computing alignments...  [31.191s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.236s]
Computing alignments...  [32.033s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.04s]
Sorting trace points...  [1.173s]
Computing alignments...  [33.206s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.036s]
Sorting trace points...  [1.318s]
Computing alignments...  [33.027s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.085s]
Sorting trace points...  [1.141s]
Computing alignments...  [32.987s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.668s]
Sorting trace points...  [1.285s]
Computing alignments...  [33.457s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.034s]
Sorting trace points...  [1.276s]
Computing alignments...  [33.234s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.298s]
Computing alignments...  [33.351s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [1.265s]
Computing alignments...  [32.797s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [543.543s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [33.818s]
Masking reference...  [30.962s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.377s]
Allocating buffers...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.113s]
Building query seed array...  [2.13s]
Computing hash join...  [5.133s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [78.734s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.27s]
Building query seed array...  [2.512s]
Computing hash join...  [5.099s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [51.436s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.329s]
Building query seed array...  [2.671s]
Computing hash join...  [5.019s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [43.388s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.964s]
Building query seed array...  [2.084s]
Computing hash join...  [5.069s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [38.513s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.335s]
Building query seed array...  [1.92s]
Computing hash join...  [4.905s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [39.234s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.887s]
Building query seed array...  [2.287s]
Computing hash join...  [4.777s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [31.396s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.149s]
Building query seed array...  [2.353s]
Computing hash join...  [4.861s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [35.829s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.603s]
Building query seed array...  [1.989s]
Computing hash join...  [4.857s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [30.609s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.129s]
Clearing query masking...  [1.605s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.399s]
Sorting trace points...  [1.246s]
Computing alignments...  [31.666s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.24s]
Computing alignments...  [31.731s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.242s]
Computing alignments...  [31.932s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.228s]
Computing alignments...  [31.617s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.153s]
Computing alignments...  [31.07s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.176s]
Computing alignments...  [31.412s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.118s]
Computing alignments...  [31.743s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.174s]
Computing alignments...  [31.283s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.066s]
Sorting trace points...  [0.994s]
Computing alignments...  [32.232s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.107s]
Sorting trace points...  [1.244s]
Computing alignments...  [33.2s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.269s]
Computing alignments...  [33.177s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.244s]
Computing alignments...  [33.159s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.263s]
Computing alignments...  [33.667s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.308s]
Computing alignments...  [33.408s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.13s]
Computing alignments...  [33.469s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
Sorting trace points...  [1.27s]
Computing alignments...  [33.105s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
 [544.755s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [31.72s]
Masking reference...  [31.604s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.144s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.477s]
Building query seed array...  [2.141s]
Computing hash join...  [5.081s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [80.449s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.483s]
Building query seed array...  [2.428s]
Computing hash join...  [5.078s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [49.911s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.484s]
Building query seed array...  [2.657s]
Computing hash join...  [5.152s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [43.873s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.133s]
Building query seed array...  [2.082s]
Computing hash join...  [5.026s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [39.124s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.166s]
Building query seed array...  [1.972s]
Computing hash join...  [4.963s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [40.72s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.37s]
Building query seed array...  [2.17s]
Computing hash join...  [4.896s]
Masking low complexity seeds...  [0.197s]
Searching alignments...  [31.616s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.605s]
Building query seed array...  [2.296s]
Computing hash join...  [4.955s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [35.116s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.225s]
Building query seed array...  [1.904s]
Computing hash join...  [4.974s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [31.332s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.615s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.346s]
Sorting trace points...  [1.208s]
Computing alignments...  [31.524s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.214s]
Computing alignments...  [31.808s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.191s]
Computing alignments...  [31.749s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.197s]
Computing alignments...  [31.607s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.158s]
Computing alignments...  [30.985s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.042s]
Sorting trace points...  [1.224s]
Computing alignments...  [31.259s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.184s]
Sorting trace points...  [1.16s]
Computing alignments...  [31.633s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.033s]
Computing alignments...  [31.253s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.075s]
Sorting trace points...  [0.952s]
Computing alignments...  [32.18s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.196s]
Computing alignments...  [33.147s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.591s]
Sorting trace points...  [1.301s]
Computing alignments...  [33.098s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.274s]
Computing alignments...  [32.978s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.309s]
Computing alignments...  [33.462s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.287s]
Computing alignments...  [33.236s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.092s]
Sorting trace points...  [1.257s]
Computing alignments...  [33.38s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [1.236s]
Computing alignments...  [32.939s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
 [543.683s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [28.239s]
Masking reference...  [25.081s]
Initializing dictionary...  [0.063s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [26.806s]
Allocating buffers...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.25s]
Building query seed array...  [2.129s]
Computing hash join...  [4.345s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [61.825s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [9.9s]
Building query seed array...  [2.479s]
Computing hash join...  [4.287s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [41.76s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [10.938s]
Building query seed array...  [2.609s]
Computing hash join...  [4.263s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [34.961s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [8.004s]
Building query seed array...  [2.086s]
Computing hash join...  [4.237s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [31.424s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [8.38s]
Building query seed array...  [1.938s]
Computing hash join...  [4.106s]
Masking low complexity seeds...  [0.199s]
Searching alignments...  [33.189s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [10.09s]
Building query seed array...  [2.285s]
Computing hash join...  [4.029s]
Masking low complexity seeds...  [0.194s]
Searching alignments...  [27.043s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [10.648s]
Building query seed array...  [2.312s]
Computing hash join...  [4.137s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [28.593s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [8.008s]
Building query seed array...  [1.939s]
Computing hash join...  [4.126s]
Masking low complexity seeds...  [0.2s]
Searching alignments...  [24.518s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.104s]
Clearing query masking...  [1.636s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [10.699s]
Sorting trace points...  [2.047s]
Computing alignments...  [50.396s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.17s]
Sorting trace points...  [1.735s]
Computing alignments...  [50.566s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.119s]
Sorting trace points...  [1.6s]
Computing alignments...  [49.584s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.152s]
Sorting trace points...  [1.603s]
Computing alignments...  [50.093s]
Deallocating buffers...  [0.034s]
Loading trace points...  [0.128s]
Sorting trace points...  [1.662s]
Computing alignments...  [51.945s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.166s]
Sorting trace points...  [2.124s]
Computing alignments...  [52.593s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.161s]
Sorting trace points...  [2.038s]
Computing alignments...  [52.903s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
Sorting trace points...  [1.921s]
Computing alignments...  [52.212s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
 [436.924s]
Deallocating reference...  [0.05s]
Loading reference sequences...  [0.09s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [1925.22s]
 [1925.22s]
Deallocating queries...  [0.068s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [3.839s]
 [4.936s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 17815s
Reported 2443740670 pairwise alignments, 2443740670 HSPs.
13629998 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C31_R1.fastp-trim.20230215.fq.gz complete: C31_R1.blastx.meganized.daa

Now MEGANizing C31_R1.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: C31_R1.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 100% (253.6s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.3s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (4,520.8s)
Total reads:       13,629,998
With hits:          13,629,998 
Alignments:      2,438,689,129
Assig. Taxonomy:    12,658,567
Assig. SEED:           115,683
Assig. EGGNOG:          68,165
Assig. GTDB:           426,656
Assig. EC:           2,226,094
Assig. INTERPRO2GO:  1,226,703
MinSupport set to: 6814
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.4s)
Min-supp. changes:       4,397
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (11.1s)
Min-supp. changes:       3,440
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (46.4s)
Binning reads Syncing
100% (0.3s)
Class. Taxonomy:            65
Class. SEED:               539
Class. EGGNOG:           1,881
Class. GTDB:                24
Class. EC:               2,483
Class. INTERPRO2GO:      7,876
Total time:  4,842s
Peak memory: 30.9 of 195.3G
MEGANization of C31_R1.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C31_R2.fastp-trim.20230215.fq.gz...
0dfc3e443fc2e16ea1e5a1af04e4f2de  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C31_R2.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C31_R2.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.312s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.758s]
Opening the output file...  [0s]
Loading query sequences...  [76.282s]
Masking queries...  [19.355s]
Algorithm: Double-indexed
Building query histograms...  [18.968s]
Loading reference sequences...  [30.392s]
Masking reference...  [31.973s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.218s]
Allocating buffers...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.556s]
Building query seed array...  [2.164s]
Computing hash join...  [5.332s]
Masking low complexity seeds...  [0.259s]
Searching alignments...  [78.217s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.888s]
Building query seed array...  [2.508s]
Computing hash join...  [5.257s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [50.055s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.14s]
Building query seed array...  [2.656s]
Computing hash join...  [5.161s]
Masking low complexity seeds...  [0.266s]
Searching alignments...  [45.886s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.839s]
Building query seed array...  [2.045s]
Computing hash join...  [5.225s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [39.566s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.938s]
Building query seed array...  [1.933s]
Computing hash join...  [5.094s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [44.307s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.46s]
Building query seed array...  [2.266s]
Computing hash join...  [5.169s]
Masking low complexity seeds...  [0.266s]
Searching alignments...  [32.548s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.493s]
Building query seed array...  [2.365s]
Computing hash join...  [5.147s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [37.484s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.627s]
Building query seed array...  [1.971s]
Computing hash join...  [4.999s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [30.461s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.623s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.473s]
Sorting trace points...  [1.277s]
Computing alignments...  [31.531s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.207s]
Computing alignments...  [31.556s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.181s]
Computing alignments...  [31.446s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.005s]
Computing alignments...  [31.229s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.154s]
Computing alignments...  [30.808s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.099s]
Sorting trace points...  [1.18s]
Computing alignments...  [31.077s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.229s]
Computing alignments...  [31.528s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.195s]
Computing alignments...  [30.884s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.214s]
Computing alignments...  [32.568s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.332s]
Computing alignments...  [33.962s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.058s]
Sorting trace points...  [0.968s]
Computing alignments...  [34.186s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.26s]
Computing alignments...  [33.88s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.314s]
Computing alignments...  [34.065s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.297s]
Computing alignments...  [33.955s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.22s]
Computing alignments...  [34.164s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [1.275s]
Computing alignments...  [33.74s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [548.626s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [30.29s]
Masking reference...  [32.197s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [31.874s]
Allocating buffers...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.196s]
Building query seed array...  [2.115s]
Computing hash join...  [5.306s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [74.527s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.79s]
Building query seed array...  [2.518s]
Computing hash join...  [5.284s]
Masking low complexity seeds...  [0.269s]
Searching alignments...  [48.77s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.507s]
Building query seed array...  [2.648s]
Computing hash join...  [5.287s]
Masking low complexity seeds...  [0.271s]
Searching alignments...  [43.917s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.699s]
Building query seed array...  [2.185s]
Computing hash join...  [5.366s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [39.235s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.39s]
Building query seed array...  [1.934s]
Computing hash join...  [5.104s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [43.206s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.27s]
Building query seed array...  [2.275s]
Computing hash join...  [5.04s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [32.505s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.616s]
Building query seed array...  [2.39s]
Computing hash join...  [5.031s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [34.807s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.965s]
Building query seed array...  [1.975s]
Computing hash join...  [5.051s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [30.877s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.623s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.229s]
Sorting trace points...  [1.263s]
Computing alignments...  [31.729s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.202s]
Computing alignments...  [31.344s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.208s]
Computing alignments...  [31.302s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.187s]
Computing alignments...  [31.636s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.049s]
Sorting trace points...  [0.952s]
Computing alignments...  [30.575s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.159s]
Computing alignments...  [30.908s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.056s]
Sorting trace points...  [0.978s]
Computing alignments...  [31.442s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.198s]
Computing alignments...  [30.746s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.245s]
Computing alignments...  [32.318s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.264s]
Computing alignments...  [33.885s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.189s]
Computing alignments...  [33.895s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.278s]
Computing alignments...  [33.694s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.196s]
Computing alignments...  [33.849s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.262s]
Computing alignments...  [33.866s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.283s]
Computing alignments...  [33.992s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
Sorting trace points...  [1.328s]
Computing alignments...  [33.631s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
 [545.325s]
Deallocating reference...  [0.07s]
Loading reference sequences...  [30.576s]
Masking reference...  [32.199s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [31.987s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.25s]
Building query seed array...  [2.173s]
Computing hash join...  [5.201s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [78.454s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.479s]
Building query seed array...  [2.43s]
Computing hash join...  [5.421s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [49.7s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.312s]
Building query seed array...  [2.59s]
Computing hash join...  [5.283s]
Masking low complexity seeds...  [0.271s]
Searching alignments...  [45.077s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.849s]
Building query seed array...  [2.078s]
Computing hash join...  [5.279s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [38.804s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.722s]
Building query seed array...  [1.939s]
Computing hash join...  [5.196s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [46.006s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.792s]
Building query seed array...  [2.295s]
Computing hash join...  [5.026s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [33.09s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.294s]
Building query seed array...  [2.373s]
Computing hash join...  [5.095s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [37.317s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.155s]
Building query seed array...  [1.887s]
Computing hash join...  [5.033s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [31.962s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.137s]
Clearing query masking...  [1.561s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.298s]
Sorting trace points...  [1.194s]
Computing alignments...  [31.725s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.18s]
Computing alignments...  [31.625s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.054s]
Sorting trace points...  [0.882s]
Computing alignments...  [31.479s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.16s]
Computing alignments...  [31.597s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.203s]
Computing alignments...  [30.699s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.089s]
Sorting trace points...  [1.131s]
Computing alignments...  [30.981s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.191s]
Computing alignments...  [31.526s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.06s]
Sorting trace points...  [0.949s]
Computing alignments...  [30.754s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.129s]
Computing alignments...  [32.504s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.205s]
Computing alignments...  [33.815s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.325s]
Computing alignments...  [33.837s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.318s]
Computing alignments...  [33.662s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.283s]
Computing alignments...  [33.916s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.226s]
Computing alignments...  [33.83s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.288s]
Computing alignments...  [33.836s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [1.331s]
Computing alignments...  [33.463s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [545.684s]
Deallocating reference...  [0.065s]
Loading reference sequences...  [36.024s]
Masking reference...  [30.883s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [31.996s]
Allocating buffers...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.434s]
Building query seed array...  [2.151s]
Computing hash join...  [5.246s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [75.953s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.322s]
Building query seed array...  [2.502s]
Computing hash join...  [5.244s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [48.288s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.429s]
Building query seed array...  [2.66s]
Computing hash join...  [5.211s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [43.171s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.638s]
Building query seed array...  [2.166s]
Computing hash join...  [5.218s]
Masking low complexity seeds...  [0.272s]
Searching alignments...  [38.693s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.162s]
Building query seed array...  [1.984s]
Computing hash join...  [5.009s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [43.736s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.724s]
Building query seed array...  [2.254s]
Computing hash join...  [5.031s]
Masking low complexity seeds...  [0.256s]
Searching alignments...  [32.235s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.269s]
Building query seed array...  [2.388s]
Computing hash join...  [4.962s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [35.707s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.061s]
Building query seed array...  [2.004s]
Computing hash join...  [5.014s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [29.975s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.128s]
Clearing query masking...  [1.579s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.2s]
Sorting trace points...  [1.239s]
Computing alignments...  [31.341s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.043s]
Computing alignments...  [31.347s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.157s]
Computing alignments...  [31.294s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.208s]
Computing alignments...  [31.019s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.046s]
Sorting trace points...  [0.925s]
Computing alignments...  [30.572s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.223s]
Computing alignments...  [30.865s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.201s]
Computing alignments...  [31.447s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.194s]
Computing alignments...  [30.705s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.045s]
Computing alignments...  [32.332s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.266s]
Computing alignments...  [33.632s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.339s]
Computing alignments...  [33.828s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.31s]
Computing alignments...  [33.621s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.173s]
Computing alignments...  [33.86s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.298s]
Computing alignments...  [33.809s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.305s]
Computing alignments...  [33.909s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
Sorting trace points...  [1.274s]
Computing alignments...  [33.457s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
 [543.519s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.801s]
Masking reference...  [30.847s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.975s]
Allocating buffers...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.244s]
Building query seed array...  [2.165s]
Computing hash join...  [5.253s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [77.518s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.47s]
Building query seed array...  [2.471s]
Computing hash join...  [5.238s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [48.061s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.498s]
Building query seed array...  [2.664s]
Computing hash join...  [5.228s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [43.576s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.101s]
Building query seed array...  [2.158s]
Computing hash join...  [5.296s]
Masking low complexity seeds...  [0.265s]
Searching alignments...  [38.048s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.099s]
Building query seed array...  [1.906s]
Computing hash join...  [5.051s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [42.693s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.701s]
Building query seed array...  [2.238s]
Computing hash join...  [5.052s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [32.833s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.32s]
Building query seed array...  [2.346s]
Computing hash join...  [5.058s]
Masking low complexity seeds...  [0.249s]
Searching alignments...  [34.975s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.84s]
Building query seed array...  [1.925s]
Computing hash join...  [4.97s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [31.367s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.122s]
Clearing query masking...  [1.601s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.316s]
Sorting trace points...  [1.245s]
Computing alignments...  [31.18s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.185s]
Computing alignments...  [31.279s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.18s]
Computing alignments...  [31.297s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.195s]
Computing alignments...  [31.121s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.181s]
Computing alignments...  [30.57s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.219s]
Computing alignments...  [30.843s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.204s]
Computing alignments...  [31.303s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.206s]
Computing alignments...  [30.532s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.243s]
Computing alignments...  [32.251s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.087s]
Sorting trace points...  [1.338s]
Computing alignments...  [33.547s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.297s]
Computing alignments...  [33.717s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.076s]
Computing alignments...  [33.527s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.172s]
Computing alignments...  [33.713s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.278s]
Computing alignments...  [33.624s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.279s]
Computing alignments...  [33.902s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [1.209s]
Computing alignments...  [33.378s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [542.781s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [29.695s]
Masking reference...  [32.08s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.902s]
Allocating buffers...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.256s]
Building query seed array...  [2.092s]
Computing hash join...  [5.196s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [75.078s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.394s]
Building query seed array...  [2.498s]
Computing hash join...  [5.294s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [47.367s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.916s]
Building query seed array...  [2.616s]
Computing hash join...  [5.15s]
Masking low complexity seeds...  [0.266s]
Searching alignments...  [42.74s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.065s]
Building query seed array...  [2.103s]
Computing hash join...  [5.208s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [38.334s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.143s]
Building query seed array...  [1.95s]
Computing hash join...  [4.957s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [41.462s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.268s]
Building query seed array...  [2.203s]
Computing hash join...  [4.99s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [32.191s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.253s]
Building query seed array...  [2.402s]
Computing hash join...  [4.97s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [34.038s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.947s]
Building query seed array...  [1.933s]
Computing hash join...  [5.094s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [29.425s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.694s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.158s]
Sorting trace points...  [1.29s]
Computing alignments...  [30.925s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.196s]
Computing alignments...  [31.132s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.102s]
Sorting trace points...  [0.916s]
Computing alignments...  [31.131s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.074s]
Sorting trace points...  [0.981s]
Computing alignments...  [30.767s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.039s]
Sorting trace points...  [1.131s]
Computing alignments...  [30.339s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.196s]
Computing alignments...  [30.672s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.044s]
Sorting trace points...  [0.955s]
Computing alignments...  [31.173s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.065s]
Sorting trace points...  [0.928s]
Computing alignments...  [30.546s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.185s]
Computing alignments...  [32.084s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.043s]
Sorting trace points...  [0.975s]
Computing alignments...  [33.438s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.085s]
Sorting trace points...  [1.26s]
Computing alignments...  [33.572s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.002s]
Sorting trace points...  [1.237s]
Computing alignments...  [33.377s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.271s]
Computing alignments...  [33.564s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.275s]
Computing alignments...  [33.644s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.135s]
Computing alignments...  [33.645s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
Sorting trace points...  [1.254s]
Computing alignments...  [33.261s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
 [538.729s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.896s]
Masking reference...  [30.834s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.849s]
Allocating buffers...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.524s]
Building query seed array...  [2.163s]
Computing hash join...  [5.264s]
Masking low complexity seeds...  [0.267s]
Searching alignments...  [79.052s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.622s]
Building query seed array...  [2.51s]
Computing hash join...  [5.208s]
Masking low complexity seeds...  [0.265s]
Searching alignments...  [50.772s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.405s]
Building query seed array...  [2.593s]
Computing hash join...  [5.128s]
Masking low complexity seeds...  [0.259s]
Searching alignments...  [44.168s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.012s]
Building query seed array...  [2.142s]
Computing hash join...  [5.196s]
Masking low complexity seeds...  [0.259s]
Searching alignments...  [38.648s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.294s]
Building query seed array...  [1.928s]
Computing hash join...  [5.031s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [44.537s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.011s]
Building query seed array...  [2.25s]
Computing hash join...  [4.922s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [32.165s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.618s]
Building query seed array...  [2.361s]
Computing hash join...  [5s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [37.063s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.719s]
Building query seed array...  [1.916s]
Computing hash join...  [5.009s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [30.961s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.136s]
Clearing query masking...  [1.585s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.336s]
Sorting trace points...  [1.247s]
Computing alignments...  [31.368s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.226s]
Computing alignments...  [31.427s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.2s]
Computing alignments...  [31.347s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.021s]
Computing alignments...  [31.044s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.074s]
Sorting trace points...  [0.926s]
Computing alignments...  [30.67s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.157s]
Computing alignments...  [30.904s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.187s]
Computing alignments...  [31.508s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.178s]
Computing alignments...  [30.747s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.192s]
Computing alignments...  [32.293s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.208s]
Computing alignments...  [33.776s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.323s]
Computing alignments...  [33.831s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.305s]
Computing alignments...  [33.731s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.127s]
Computing alignments...  [33.996s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.233s]
Computing alignments...  [33.791s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.33s]
Computing alignments...  [33.917s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [1.254s]
Computing alignments...  [33.408s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [544.348s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.738s]
Masking reference...  [32.011s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [31.899s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.176s]
Building query seed array...  [2.089s]
Computing hash join...  [5.269s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [76.466s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.655s]
Building query seed array...  [2.451s]
Computing hash join...  [5.165s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [48.174s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.344s]
Building query seed array...  [2.726s]
Computing hash join...  [5.174s]
Masking low complexity seeds...  [0.266s]
Searching alignments...  [43.557s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.331s]
Building query seed array...  [2.12s]
Computing hash join...  [5.158s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [38.133s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.249s]
Building query seed array...  [1.912s]
Computing hash join...  [5.06s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [41.909s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.15s]
Building query seed array...  [2.235s]
Computing hash join...  [5.033s]
Masking low complexity seeds...  [0.249s]
Searching alignments...  [32.451s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.088s]
Building query seed array...  [2.345s]
Computing hash join...  [5.075s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [35.71s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.404s]
Building query seed array...  [1.957s]
Computing hash join...  [5.012s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [30.111s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.147s]
Clearing query masking...  [1.678s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.367s]
Sorting trace points...  [1.243s]
Computing alignments...  [31.237s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.216s]
Computing alignments...  [31.373s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.228s]
Computing alignments...  [31.318s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.168s]
Computing alignments...  [31.103s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.185s]
Computing alignments...  [30.692s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.198s]
Computing alignments...  [30.84s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.068s]
Sorting trace points...  [0.894s]
Computing alignments...  [31.373s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.155s]
Computing alignments...  [30.659s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.231s]
Computing alignments...  [32.369s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.108s]
Sorting trace points...  [1.306s]
Computing alignments...  [33.703s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.366s]
Computing alignments...  [33.788s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.291s]
Computing alignments...  [33.635s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.064s]
Sorting trace points...  [0.971s]
Computing alignments...  [33.869s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.151s]
Computing alignments...  [33.786s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.256s]
Computing alignments...  [33.857s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
Sorting trace points...  [1.314s]
Computing alignments...  [33.473s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [543.862s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.617s]
Masking reference...  [30.829s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.719s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.193s]
Building query seed array...  [2.149s]
Computing hash join...  [5.268s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [78.554s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.202s]
Building query seed array...  [2.513s]
Computing hash join...  [5.189s]
Masking low complexity seeds...  [0.256s]
Searching alignments...  [48.15s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.978s]
Building query seed array...  [2.621s]
Computing hash join...  [5.272s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [44.835s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.378s]
Building query seed array...  [2.13s]
Computing hash join...  [5.445s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [38.402s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.868s]
Building query seed array...  [1.908s]
Computing hash join...  [5.09s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [43.143s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.442s]
Building query seed array...  [2.208s]
Computing hash join...  [5.042s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [32.62s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.249s]
Building query seed array...  [2.367s]
Computing hash join...  [5.036s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [35.191s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.876s]
Building query seed array...  [1.941s]
Computing hash join...  [5.935s]
Masking low complexity seeds...  [0.259s]
Searching alignments...  [29.966s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.137s]
Clearing query masking...  [1.654s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.485s]
Sorting trace points...  [1.153s]
Computing alignments...  [31.186s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.187s]
Computing alignments...  [31.226s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.05s]
Sorting trace points...  [0.95s]
Computing alignments...  [31.237s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.186s]
Computing alignments...  [30.975s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.116s]
Computing alignments...  [30.533s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.102s]
Sorting trace points...  [1.202s]
Computing alignments...  [30.853s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.202s]
Computing alignments...  [31.383s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.03s]
Sorting trace points...  [1.182s]
Computing alignments...  [30.617s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.237s]
Computing alignments...  [32.308s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.31s]
Computing alignments...  [33.653s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.03s]
Computing alignments...  [33.828s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.2s]
Computing alignments...  [33.616s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.334s]
Computing alignments...  [33.836s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.021s]
Computing alignments...  [33.701s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.196s]
Computing alignments...  [33.788s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
Sorting trace points...  [1.317s]
Computing alignments...  [33.395s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [542.63s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [29.787s]
Masking reference...  [30.839s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.745s]
Allocating buffers...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.115s]
Building query seed array...  [2.108s]
Computing hash join...  [5.259s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [78.103s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.249s]
Building query seed array...  [2.47s]
Computing hash join...  [5.237s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [49.045s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.243s]
Building query seed array...  [2.662s]
Computing hash join...  [5.235s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [43.536s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.873s]
Building query seed array...  [2.113s]
Computing hash join...  [5.279s]
Masking low complexity seeds...  [0.28s]
Searching alignments...  [38.232s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.881s]
Building query seed array...  [1.907s]
Computing hash join...  [5.096s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [43.67s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.384s]
Building query seed array...  [2.263s]
Computing hash join...  [5.017s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [33.135s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.323s]
Building query seed array...  [2.425s]
Computing hash join...  [5.078s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [36.273s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.121s]
Building query seed array...  [1.899s]
Computing hash join...  [5.046s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [30.683s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.615s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.248s]
Sorting trace points...  [1.259s]
Computing alignments...  [31.252s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.002s]
Computing alignments...  [31.263s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.192s]
Computing alignments...  [31.461s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.191s]
Computing alignments...  [31.062s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.058s]
Sorting trace points...  [0.973s]
Computing alignments...  [30.619s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.197s]
Computing alignments...  [30.868s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.173s]
Computing alignments...  [31.39s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.203s]
Computing alignments...  [30.759s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.229s]
Sorting trace points...  [1.027s]
Computing alignments...  [32.348s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.081s]
Sorting trace points...  [0.977s]
Computing alignments...  [33.671s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [0.965s]
Computing alignments...  [33.782s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.268s]
Computing alignments...  [33.568s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.326s]
Computing alignments...  [33.846s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.055s]
Sorting trace points...  [0.987s]
Computing alignments...  [33.746s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.315s]
Computing alignments...  [33.964s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.272s]
Computing alignments...  [33.503s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [543.035s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.827s]
Masking reference...  [30.895s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.786s]
Allocating buffers...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.013s]
Building query seed array...  [2.171s]
Computing hash join...  [5.304s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [75.838s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.908s]
Building query seed array...  [2.342s]
Computing hash join...  [5.276s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [47.768s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.497s]
Building query seed array...  [2.688s]
Computing hash join...  [5.228s]
Masking low complexity seeds...  [0.266s]
Searching alignments...  [43.144s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.934s]
Building query seed array...  [2.083s]
Computing hash join...  [5.262s]
Masking low complexity seeds...  [0.265s]
Searching alignments...  [37.924s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.911s]
Building query seed array...  [1.976s]
Computing hash join...  [5.073s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [41.501s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.579s]
Building query seed array...  [2.214s]
Computing hash join...  [5.034s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [32.587s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.286s]
Building query seed array...  [2.365s]
Computing hash join...  [4.952s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [34.996s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.711s]
Building query seed array...  [1.934s]
Computing hash join...  [5.039s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [30.045s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.665s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.258s]
Sorting trace points...  [1.205s]
Computing alignments...  [31.456s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.097s]
Sorting trace points...  [1.228s]
Computing alignments...  [31.413s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.197s]
Computing alignments...  [31.318s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.065s]
Computing alignments...  [31.482s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.046s]
Computing alignments...  [30.627s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.15s]
Computing alignments...  [30.797s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.056s]
Sorting trace points...  [0.961s]
Computing alignments...  [31.333s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.073s]
Sorting trace points...  [0.929s]
Computing alignments...  [30.676s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.002s]
Sorting trace points...  [1.27s]
Computing alignments...  [32.26s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.033s]
Sorting trace points...  [1.28s]
Computing alignments...  [33.58s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.277s]
Computing alignments...  [33.756s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.282s]
Computing alignments...  [33.545s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.331s]
Computing alignments...  [33.894s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.03s]
Computing alignments...  [33.813s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.252s]
Computing alignments...  [33.896s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [1.244s]
Computing alignments...  [33.306s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
 [543.222s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [29.632s]
Masking reference...  [30.847s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.7s]
Allocating buffers...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.662s]
Building query seed array...  [2.118s]
Computing hash join...  [5.316s]
Masking low complexity seeds...  [0.267s]
Searching alignments...  [78.167s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.858s]
Building query seed array...  [2.458s]
Computing hash join...  [5.286s]
Masking low complexity seeds...  [0.267s]
Searching alignments...  [48.537s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.538s]
Building query seed array...  [2.663s]
Computing hash join...  [5.174s]
Masking low complexity seeds...  [0.27s]
Searching alignments...  [44.062s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.392s]
Building query seed array...  [2.084s]
Computing hash join...  [5.181s]
Masking low complexity seeds...  [0.259s]
Searching alignments...  [38.636s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.068s]
Building query seed array...  [1.884s]
Computing hash join...  [4.955s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [43.193s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.267s]
Building query seed array...  [2.209s]
Computing hash join...  [5.041s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [32.505s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.336s]
Building query seed array...  [2.323s]
Computing hash join...  [5.027s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [35.819s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.839s]
Building query seed array...  [1.989s]
Computing hash join...  [5.074s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [31.305s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.121s]
Clearing query masking...  [1.64s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.474s]
Sorting trace points...  [1.251s]
Computing alignments...  [31.372s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.077s]
Sorting trace points...  [0.967s]
Computing alignments...  [31.426s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.223s]
Computing alignments...  [31.43s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [0.856s]
Computing alignments...  [31.295s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.192s]
Computing alignments...  [30.684s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.097s]
Sorting trace points...  [1.186s]
Computing alignments...  [31.004s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.191s]
Sorting trace points...  [1.22s]
Computing alignments...  [31.554s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.203s]
Computing alignments...  [30.668s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.19s]
Sorting trace points...  [1.193s]
Computing alignments...  [32.313s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.287s]
Computing alignments...  [33.641s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.105s]
Computing alignments...  [33.873s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.304s]
Computing alignments...  [33.576s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.201s]
Sorting trace points...  [1.34s]
Computing alignments...  [33.825s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.292s]
Computing alignments...  [33.745s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.276s]
Computing alignments...  [33.954s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [1.251s]
Computing alignments...  [33.561s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [545.061s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [29.884s]
Masking reference...  [32.144s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.432s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [9.934s]
Building query seed array...  [2.134s]
Computing hash join...  [5.26s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [77.692s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.166s]
Building query seed array...  [2.489s]
Computing hash join...  [5.276s]
Masking low complexity seeds...  [0.268s]
Searching alignments...  [48.434s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.489s]
Building query seed array...  [2.677s]
Computing hash join...  [5.136s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [44.027s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.032s]
Building query seed array...  [2.125s]
Computing hash join...  [5.182s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [39.04s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.204s]
Building query seed array...  [1.904s]
Computing hash join...  [4.933s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [43.328s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.115s]
Building query seed array...  [2.239s]
Computing hash join...  [5.095s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [32.689s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.414s]
Building query seed array...  [2.364s]
Computing hash join...  [5.002s]
Masking low complexity seeds...  [0.249s]
Searching alignments...  [35.505s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.173s]
Building query seed array...  [1.905s]
Computing hash join...  [4.982s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [30.387s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.13s]
Clearing query masking...  [1.652s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.257s]
Sorting trace points...  [1.23s]
Computing alignments...  [31.441s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.059s]
Sorting trace points...  [0.94s]
Computing alignments...  [31.257s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.188s]
Computing alignments...  [31.35s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.171s]
Computing alignments...  [31.356s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.166s]
Computing alignments...  [30.617s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.069s]
Sorting trace points...  [0.983s]
Computing alignments...  [30.843s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.828s]
Sorting trace points...  [0.995s]
Computing alignments...  [31.369s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.141s]
Computing alignments...  [30.7s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.278s]
Computing alignments...  [32.29s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.179s]
Computing alignments...  [33.721s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.094s]
Sorting trace points...  [1.134s]
Computing alignments...  [33.76s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.35s]
Computing alignments...  [33.487s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.074s]
Computing alignments...  [33.683s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.799s]
Sorting trace points...  [1.074s]
Computing alignments...  [33.656s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.087s]
Sorting trace points...  [1.283s]
Computing alignments...  [33.677s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0s]
Sorting trace points...  [1.287s]
Computing alignments...  [33.3s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [543.931s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [25.722s]
Masking reference...  [26.177s]
Initializing dictionary...  [0.063s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [25.479s]
Allocating buffers...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.106s]
Building query seed array...  [2.138s]
Computing hash join...  [4.315s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [61.504s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [10.054s]
Building query seed array...  [2.429s]
Computing hash join...  [4.385s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [40.405s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [10.761s]
Building query seed array...  [2.708s]
Computing hash join...  [4.373s]
Masking low complexity seeds...  [0.259s]
Searching alignments...  [36.354s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [7.781s]
Building query seed array...  [2.213s]
Computing hash join...  [4.425s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [31.378s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [8.095s]
Building query seed array...  [2s]
Computing hash join...  [4.185s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [34.966s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [9.87s]
Building query seed array...  [2.181s]
Computing hash join...  [4.149s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [27.092s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [10.923s]
Building query seed array...  [2.376s]
Computing hash join...  [4.294s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [29.574s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [8.096s]
Building query seed array...  [1.897s]
Computing hash join...  [4.233s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [24.879s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.117s]
Clearing query masking...  [1.609s]
Opening temporary output file...  [0.002s]
Computing alignments... Loading trace points...  [10.675s]
Sorting trace points...  [1.826s]
Computing alignments...  [49.684s]
Deallocating buffers...  [0.032s]
Loading trace points...  [1.174s]
Sorting trace points...  [2.062s]
Computing alignments...  [49.468s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.101s]
Sorting trace points...  [1.972s]
Computing alignments...  [48.916s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.147s]
Sorting trace points...  [1.918s]
Computing alignments...  [49.472s]
Deallocating buffers...  [0.034s]
Loading trace points...  [0.144s]
Sorting trace points...  [2.129s]
Computing alignments...  [52.475s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.068s]
Sorting trace points...  [2.191s]
Computing alignments...  [53.599s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.066s]
Sorting trace points...  [2.06s]
Computing alignments...  [53.663s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
Sorting trace points...  [1.654s]
Computing alignments...  [53.007s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0s]
 [438.825s]
Deallocating reference...  [0.048s]
Loading reference sequences...  [0.076s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [1885.26s]
 [1885.26s]
Deallocating queries...  [0.066s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [3.787s]
 [4.916s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 17810.5s
Reported 2358654581 pairwise alignments, 2358654581 HSPs.
13991947 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C31_R2.fastp-trim.20230215.fq.gz complete: C31_R2.blastx.meganized.daa

Now MEGANizing C31_R2.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: C31_R2.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 80% 100% (289.0s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.3s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (4,469.1s)
Total reads:       13,991,947
With hits:          13,991,947 
Alignments:      2,353,816,450
Assig. Taxonomy:    12,951,974
Assig. SEED:           111,842
Assig. EGGNOG:          66,876
Assig. GTDB:           412,811
Assig. EC:           2,275,638
Assig. INTERPRO2GO:  1,221,007
MinSupport set to: 6995
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.4s)
Min-supp. changes:       4,531
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (10.0s)
Min-supp. changes:       3,641
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (35.4s)
Binning reads Syncing
100% (0.4s)
Class. Taxonomy:            64
Class. SEED:               533
Class. EGGNOG:           1,876
Class. GTDB:                18
Class. EC:               2,453
Class. INTERPRO2GO:      7,977
Total time:  4,814s
Peak memory: 35.4 of 195.3G
MEGANization of C31_R2.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C32_R1.fastp-trim.20230215.fq.gz...
60ee58280a66907aa4b3a048499fd61d  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C32_R1.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C32_R1.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.371s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.729s]
Opening the output file...  [0s]
Loading query sequences...  [81.429s]
Masking queries...  [21.094s]
Algorithm: Double-indexed
Building query histograms...  [20.189s]
Loading reference sequences...  [29.483s]
Masking reference...  [30.823s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [33.061s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.365s]
Building query seed array...  [2.314s]
Computing hash join...  [5.397s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [78.906s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.288s]
Building query seed array...  [2.674s]
Computing hash join...  [5.252s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [51.733s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [14.119s]
Building query seed array...  [2.835s]
Computing hash join...  [5.154s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [46.871s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.894s]
Building query seed array...  [2.3s]
Computing hash join...  [5.235s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [39.302s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.92s]
Building query seed array...  [2.018s]
Computing hash join...  [5.08s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [40.706s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.829s]
Building query seed array...  [2.46s]
Computing hash join...  [4.964s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [33.563s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.455s]
Building query seed array...  [2.577s]
Computing hash join...  [4.95s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [37.051s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.102s]
Building query seed array...  [2.067s]
Computing hash join...  [4.989s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [31.346s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.8s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.682s]
Sorting trace points...  [1.24s]
Computing alignments...  [33.084s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.112s]
Computing alignments...  [32.996s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.095s]
Sorting trace points...  [0.959s]
Computing alignments...  [32.856s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.241s]
Computing alignments...  [32.954s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.245s]
Computing alignments...  [32.932s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.038s]
Sorting trace points...  [1.084s]
Computing alignments...  [33.457s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.255s]
Computing alignments...  [32.802s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.194s]
Computing alignments...  [32.994s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.169s]
Computing alignments...  [33.922s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.01s]
Computing alignments...  [34.393s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.308s]
Computing alignments...  [34.165s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.298s]
Computing alignments...  [34.155s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.256s]
Computing alignments...  [34.144s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.136s]
Sorting trace points...  [0.962s]
Computing alignments...  [34.22s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.331s]
Computing alignments...  [34.188s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.297s]
Computing alignments...  [34.082s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [564.236s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [29.701s]
Masking reference...  [30.921s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.053s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.461s]
Building query seed array...  [2.349s]
Computing hash join...  [5.242s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [78.247s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.322s]
Building query seed array...  [2.574s]
Computing hash join...  [5.262s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [49.548s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.411s]
Building query seed array...  [2.847s]
Computing hash join...  [5.205s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [46.454s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.272s]
Building query seed array...  [2.237s]
Computing hash join...  [5.341s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [40.644s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.167s]
Building query seed array...  [2.089s]
Computing hash join...  [5.121s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [41.069s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.061s]
Building query seed array...  [2.362s]
Computing hash join...  [5.045s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [32.537s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [14.013s]
Building query seed array...  [2.53s]
Computing hash join...  [5.023s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [34.88s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.46s]
Building query seed array...  [2.148s]
Computing hash join...  [4.991s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [30.781s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.131s]
Clearing query masking...  [1.757s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.421s]
Sorting trace points...  [1.273s]
Computing alignments...  [32.884s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.085s]
Sorting trace points...  [1.026s]
Computing alignments...  [32.937s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.125s]
Computing alignments...  [32.759s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.245s]
Computing alignments...  [32.69s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.093s]
Sorting trace points...  [1.236s]
Computing alignments...  [32.667s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.002s]
Computing alignments...  [33.163s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.138s]
Sorting trace points...  [1.281s]
Computing alignments...  [32.714s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.188s]
Computing alignments...  [32.879s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.042s]
Sorting trace points...  [1.29s]
Computing alignments...  [33.792s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.311s]
Computing alignments...  [34.284s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.05s]
Sorting trace points...  [0.979s]
Computing alignments...  [34.281s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.084s]
Sorting trace points...  [1.204s]
Computing alignments...  [34.191s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.129s]
Computing alignments...  [34.228s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.001s]
Sorting trace points...  [0.921s]
Computing alignments...  [34.246s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.279s]
Computing alignments...  [34.227s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.269s]
Computing alignments...  [33.897s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [562.356s]
Deallocating reference...  [0.063s]
Loading reference sequences...  [29.295s]
Masking reference...  [30.932s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.679s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.162s]
Building query seed array...  [2.329s]
Computing hash join...  [5.263s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [79.816s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.522s]
Building query seed array...  [2.677s]
Computing hash join...  [5.311s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [52.651s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.628s]
Building query seed array...  [2.744s]
Computing hash join...  [5.22s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [46.459s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.888s]
Building query seed array...  [2.295s]
Computing hash join...  [5.169s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [40.152s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.563s]
Building query seed array...  [2.042s]
Computing hash join...  [5.065s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [41.615s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.058s]
Building query seed array...  [2.417s]
Computing hash join...  [4.985s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [32.741s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.344s]
Building query seed array...  [2.508s]
Computing hash join...  [5.017s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [35.938s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.205s]
Building query seed array...  [2.054s]
Computing hash join...  [4.929s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [32.194s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.128s]
Clearing query masking...  [1.757s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.493s]
Sorting trace points...  [1.3s]
Computing alignments...  [32.709s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.156s]
Computing alignments...  [32.773s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.1s]
Sorting trace points...  [1.191s]
Computing alignments...  [32.648s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.222s]
Computing alignments...  [32.728s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.011s]
Computing alignments...  [32.642s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.223s]
Computing alignments...  [33.105s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.105s]
Sorting trace points...  [1.24s]
Computing alignments...  [32.624s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.226s]
Computing alignments...  [32.857s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.151s]
Computing alignments...  [33.874s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.085s]
Computing alignments...  [34.257s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.281s]
Computing alignments...  [34.07s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.326s]
Computing alignments...  [34.003s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.13s]
Computing alignments...  [34.017s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.282s]
Computing alignments...  [34.085s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.28s]
Computing alignments...  [34.096s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.077s]
Computing alignments...  [33.894s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [561.234s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [30.073s]
Masking reference...  [30.877s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.365s]
Allocating buffers...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.408s]
Building query seed array...  [2.259s]
Computing hash join...  [5.27s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [78.255s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.362s]
Building query seed array...  [2.633s]
Computing hash join...  [5.276s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [49.559s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.386s]
Building query seed array...  [2.763s]
Computing hash join...  [5.206s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [47.619s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.941s]
Building query seed array...  [2.238s]
Computing hash join...  [5.195s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [40.563s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.199s]
Building query seed array...  [2.077s]
Computing hash join...  [4.957s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [40.384s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.569s]
Building query seed array...  [2.343s]
Computing hash join...  [5.002s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [34.383s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.262s]
Building query seed array...  [2.569s]
Computing hash join...  [5.036s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [35.734s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.989s]
Building query seed array...  [2.224s]
Computing hash join...  [4.977s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [30.506s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.13s]
Clearing query masking...  [1.764s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.432s]
Sorting trace points...  [1.294s]
Computing alignments...  [32.685s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.236s]
Computing alignments...  [32.828s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.088s]
Sorting trace points...  [1.233s]
Computing alignments...  [32.757s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.201s]
Computing alignments...  [32.689s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.246s]
Computing alignments...  [32.752s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.001s]
Sorting trace points...  [0.919s]
Computing alignments...  [33.19s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.089s]
Sorting trace points...  [1.24s]
Computing alignments...  [32.718s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.207s]
Computing alignments...  [32.882s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.239s]
Computing alignments...  [33.937s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.316s]
Computing alignments...  [34.265s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.087s]
Sorting trace points...  [1.216s]
Computing alignments...  [34.153s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.272s]
Computing alignments...  [34.142s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.265s]
Computing alignments...  [34.284s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.039s]
Sorting trace points...  [1.323s]
Computing alignments...  [34.187s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.283s]
Computing alignments...  [34.289s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.279s]
Computing alignments...  [34.014s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
 [563.15s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [32.392s]
Masking reference...  [31.964s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [31.905s]
Allocating buffers...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.39s]
Building query seed array...  [2.284s]
Computing hash join...  [5.314s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [77.631s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.465s]
Building query seed array...  [2.645s]
Computing hash join...  [5.142s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [50.815s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.264s]
Building query seed array...  [2.853s]
Computing hash join...  [5.191s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [45.77s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.825s]
Building query seed array...  [2.264s]
Computing hash join...  [5.256s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [38.86s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.037s]
Building query seed array...  [2.03s]
Computing hash join...  [5.052s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [40.015s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.404s]
Building query seed array...  [2.339s]
Computing hash join...  [4.991s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [33.466s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.157s]
Building query seed array...  [2.454s]
Computing hash join...  [4.847s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [35.712s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.954s]
Building query seed array...  [2.114s]
Computing hash join...  [4.949s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [32.145s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.122s]
Clearing query masking...  [1.682s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.533s]
Sorting trace points...  [1.317s]
Computing alignments...  [32.741s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.607s]
Sorting trace points...  [1.257s]
Computing alignments...  [32.686s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.249s]
Computing alignments...  [32.719s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.22s]
Computing alignments...  [32.702s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.208s]
Computing alignments...  [32.611s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.085s]
Sorting trace points...  [1.265s]
Computing alignments...  [33.087s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.237s]
Computing alignments...  [32.6s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.216s]
Computing alignments...  [32.779s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.798s]
Sorting trace points...  [1.3s]
Computing alignments...  [33.723s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.004s]
Computing alignments...  [34.193s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.235s]
Computing alignments...  [34.084s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.279s]
Computing alignments...  [33.995s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.251s]
Computing alignments...  [34.031s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.103s]
Sorting trace points...  [1.278s]
Computing alignments...  [34.154s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.351s]
Computing alignments...  [34.158s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.279s]
Computing alignments...  [33.955s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [563.347s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [29.414s]
Masking reference...  [30.829s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.964s]
Allocating buffers...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.404s]
Building query seed array...  [2.332s]
Computing hash join...  [5.204s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [75.258s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.484s]
Building query seed array...  [2.614s]
Computing hash join...  [5.203s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [48.548s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.221s]
Building query seed array...  [2.811s]
Computing hash join...  [5.211s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [43.977s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.3s]
Building query seed array...  [2.26s]
Computing hash join...  [5.173s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [38.561s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.302s]
Building query seed array...  [2.097s]
Computing hash join...  [4.955s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [39.971s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.223s]
Building query seed array...  [2.398s]
Computing hash join...  [4.992s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [32.758s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.15s]
Building query seed array...  [2.551s]
Computing hash join...  [5.039s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [34.893s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.219s]
Building query seed array...  [2.092s]
Computing hash join...  [4.963s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [30.032s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.713s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.447s]
Sorting trace points...  [1.289s]
Computing alignments...  [32.627s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.229s]
Computing alignments...  [32.626s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.104s]
Sorting trace points...  [1.238s]
Computing alignments...  [32.518s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.199s]
Computing alignments...  [32.502s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.231s]
Computing alignments...  [32.391s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.189s]
Computing alignments...  [32.887s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.036s]
Computing alignments...  [32.447s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.119s]
Computing alignments...  [32.567s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.273s]
Computing alignments...  [33.537s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.327s]
Computing alignments...  [33.948s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.234s]
Computing alignments...  [34.014s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.293s]
Computing alignments...  [33.867s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.186s]
Computing alignments...  [33.887s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.288s]
Computing alignments...  [34.022s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.079s]
Computing alignments...  [33.925s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.166s]
Computing alignments...  [33.711s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
 [558.552s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.467s]
Masking reference...  [30.842s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.725s]
Allocating buffers...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.111s]
Building query seed array...  [2.396s]
Computing hash join...  [5.222s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [79.169s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.594s]
Building query seed array...  [2.607s]
Computing hash join...  [5.217s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [50.97s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.536s]
Building query seed array...  [2.967s]
Computing hash join...  [5.256s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [46.228s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.249s]
Building query seed array...  [2.324s]
Computing hash join...  [5.213s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [41.467s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.9s]
Building query seed array...  [2.109s]
Computing hash join...  [4.995s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [40.35s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.5s]
Building query seed array...  [2.389s]
Computing hash join...  [5.05s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [32.664s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.48s]
Building query seed array...  [2.47s]
Computing hash join...  [4.928s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [35.852s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.101s]
Building query seed array...  [2.068s]
Computing hash join...  [4.881s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [31.424s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.138s]
Clearing query masking...  [1.738s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.631s]
Sorting trace points...  [1.318s]
Computing alignments...  [32.946s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.256s]
Computing alignments...  [32.905s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.089s]
Sorting trace points...  [0.931s]
Computing alignments...  [32.73s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.104s]
Sorting trace points...  [1.278s]
Computing alignments...  [32.725s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.224s]
Computing alignments...  [32.68s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.256s]
Computing alignments...  [33.252s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.222s]
Computing alignments...  [32.662s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.2s]
Computing alignments...  [32.955s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.009s]
Computing alignments...  [33.921s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.233s]
Computing alignments...  [34.261s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.31s]
Computing alignments...  [34.207s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.271s]
Computing alignments...  [34.162s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.266s]
Computing alignments...  [34.261s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.314s]
Computing alignments...  [34.215s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.317s]
Computing alignments...  [34.197s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.179s]
Computing alignments...  [34.066s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [563.404s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [29.602s]
Masking reference...  [30.828s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.712s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.044s]
Building query seed array...  [2.311s]
Computing hash join...  [5.305s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [78.502s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.161s]
Building query seed array...  [2.565s]
Computing hash join...  [5.267s]
Masking low complexity seeds...  [0.249s]
Searching alignments...  [51.59s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.129s]
Building query seed array...  [2.797s]
Computing hash join...  [5.12s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [45.166s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.047s]
Building query seed array...  [2.318s]
Computing hash join...  [5.114s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [40.198s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.164s]
Building query seed array...  [2.053s]
Computing hash join...  [4.97s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [40.65s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.329s]
Building query seed array...  [2.394s]
Computing hash join...  [4.921s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [32.443s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.494s]
Building query seed array...  [2.566s]
Computing hash join...  [4.866s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [35.969s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.847s]
Building query seed array...  [2.053s]
Computing hash join...  [4.986s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [31.999s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.14s]
Clearing query masking...  [1.764s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.687s]
Sorting trace points...  [1.256s]
Computing alignments...  [32.79s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.029s]
Sorting trace points...  [0.98s]
Computing alignments...  [32.806s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.194s]
Computing alignments...  [32.567s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.209s]
Computing alignments...  [32.64s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.253s]
Computing alignments...  [32.645s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.033s]
Computing alignments...  [33.137s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.235s]
Computing alignments...  [32.573s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.261s]
Computing alignments...  [32.743s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.055s]
Computing alignments...  [33.646s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.096s]
Sorting trace points...  [1.301s]
Computing alignments...  [34.131s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.088s]
Sorting trace points...  [1.26s]
Computing alignments...  [34.072s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.316s]
Computing alignments...  [33.917s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.335s]
Computing alignments...  [33.938s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.317s]
Computing alignments...  [34.037s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.162s]
Computing alignments...  [34.041s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [0.975s]
Computing alignments...  [33.859s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
 [560.5s]
Deallocating reference...  [0.074s]
Loading reference sequences...  [29.736s]
Masking reference...  [32.094s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.095s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.233s]
Building query seed array...  [2.233s]
Computing hash join...  [5.269s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [79.042s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.335s]
Building query seed array...  [2.622s]
Computing hash join...  [5.173s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [50.69s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.528s]
Building query seed array...  [2.759s]
Computing hash join...  [5.18s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [46.563s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.05s]
Building query seed array...  [2.223s]
Computing hash join...  [5.125s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [40.946s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.222s]
Building query seed array...  [2.027s]
Computing hash join...  [5.055s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [40.543s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.21s]
Building query seed array...  [2.341s]
Computing hash join...  [5.045s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [32.276s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.117s]
Building query seed array...  [2.467s]
Computing hash join...  [5.062s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [35.425s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.082s]
Building query seed array...  [2.093s]
Computing hash join...  [4.959s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [30.699s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.732s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.863s]
Sorting trace points...  [1.291s]
Computing alignments...  [32.685s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [1.228s]
Computing alignments...  [32.914s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.263s]
Computing alignments...  [32.614s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.102s]
Computing alignments...  [32.476s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.212s]
Computing alignments...  [32.515s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.206s]
Computing alignments...  [33.034s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.069s]
Sorting trace points...  [0.935s]
Computing alignments...  [32.508s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.753s]
Sorting trace points...  [1.224s]
Computing alignments...  [32.697s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.291s]
Computing alignments...  [33.839s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.33s]
Computing alignments...  [34.071s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.259s]
Computing alignments...  [33.91s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.328s]
Computing alignments...  [33.819s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.264s]
Computing alignments...  [33.923s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.256s]
Computing alignments...  [33.98s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.161s]
Computing alignments...  [33.986s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.042s]
Computing alignments...  [33.756s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [561.006s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [29.424s]
Masking reference...  [30.843s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.894s]
Allocating buffers...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.472s]
Building query seed array...  [2.314s]
Computing hash join...  [5.268s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [80.481s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.149s]
Building query seed array...  [2.703s]
Computing hash join...  [5.171s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [52.031s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.589s]
Building query seed array...  [2.925s]
Computing hash join...  [5.221s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [44.891s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.072s]
Building query seed array...  [2.273s]
Computing hash join...  [5.072s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [39.386s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.001s]
Building query seed array...  [2.105s]
Computing hash join...  [5.004s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [41.017s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.304s]
Building query seed array...  [2.439s]
Computing hash join...  [4.997s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [32.617s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.089s]
Building query seed array...  [2.508s]
Computing hash join...  [5.022s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [37.774s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.043s]
Building query seed array...  [2.11s]
Computing hash join...  [5.085s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [30.729s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.742s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.441s]
Sorting trace points...  [1.328s]
Computing alignments...  [32.837s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.068s]
Computing alignments...  [32.852s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.235s]
Computing alignments...  [32.637s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.095s]
Sorting trace points...  [1.215s]
Computing alignments...  [32.662s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.086s]
Sorting trace points...  [0.989s]
Computing alignments...  [32.705s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.222s]
Computing alignments...  [33.065s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.249s]
Computing alignments...  [32.502s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.062s]
Sorting trace points...  [0.998s]
Computing alignments...  [32.775s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.253s]
Computing alignments...  [33.696s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.311s]
Computing alignments...  [34.012s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.296s]
Computing alignments...  [33.898s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.284s]
Computing alignments...  [33.85s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.293s]
Computing alignments...  [33.878s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.325s]
Sorting trace points...  [0.963s]
Computing alignments...  [33.968s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.279s]
Computing alignments...  [34.012s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.218s]
Computing alignments...  [33.702s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
 [560.33s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [29.589s]
Masking reference...  [32.095s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [31.764s]
Allocating buffers...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.369s]
Building query seed array...  [2.322s]
Computing hash join...  [5.182s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [77.464s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.139s]
Building query seed array...  [2.626s]
Computing hash join...  [5.247s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [48.965s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.716s]
Building query seed array...  [2.827s]
Computing hash join...  [5.192s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [46.615s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.342s]
Building query seed array...  [2.208s]
Computing hash join...  [5.204s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [40.861s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.147s]
Building query seed array...  [2.048s]
Computing hash join...  [4.947s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [40.029s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.361s]
Building query seed array...  [2.408s]
Computing hash join...  [4.947s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [32.336s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.643s]
Building query seed array...  [2.511s]
Computing hash join...  [4.963s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [34.877s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.943s]
Building query seed array...  [2.076s]
Computing hash join...  [4.967s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [30.241s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.13s]
Clearing query masking...  [1.785s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.573s]
Sorting trace points...  [0.966s]
Computing alignments...  [32.643s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.092s]
Computing alignments...  [32.581s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.236s]
Computing alignments...  [32.46s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.192s]
Computing alignments...  [32.49s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.075s]
Computing alignments...  [32.414s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.211s]
Computing alignments...  [32.949s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.21s]
Computing alignments...  [32.472s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.19s]
Computing alignments...  [32.659s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.082s]
Computing alignments...  [33.735s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.203s]
Computing alignments...  [33.978s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.286s]
Computing alignments...  [33.919s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.063s]
Sorting trace points...  [0.994s]
Computing alignments...  [33.833s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.306s]
Computing alignments...  [33.898s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.006s]
Computing alignments...  [33.98s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.08s]
Computing alignments...  [34.055s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.072s]
Computing alignments...  [33.757s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [557.893s]
Deallocating reference...  [0.07s]
Loading reference sequences...  [29.713s]
Masking reference...  [30.827s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.733s]
Allocating buffers...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.224s]
Building query seed array...  [2.27s]
Computing hash join...  [5.248s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [78.147s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.559s]
Building query seed array...  [2.657s]
Computing hash join...  [5.251s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [50.792s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.537s]
Building query seed array...  [2.753s]
Computing hash join...  [5.142s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [44.677s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.232s]
Building query seed array...  [2.26s]
Computing hash join...  [5.188s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [40.278s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.915s]
Building query seed array...  [2.026s]
Computing hash join...  [5.033s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [40.769s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.282s]
Building query seed array...  [2.465s]
Computing hash join...  [5.041s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [32.678s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.45s]
Building query seed array...  [2.525s]
Computing hash join...  [4.931s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [35.926s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.939s]
Building query seed array...  [2.055s]
Computing hash join...  [4.983s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [30.594s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.133s]
Clearing query masking...  [1.758s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.542s]
Sorting trace points...  [1.324s]
Computing alignments...  [32.89s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.002s]
Sorting trace points...  [1.206s]
Computing alignments...  [32.746s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.084s]
Sorting trace points...  [0.945s]
Computing alignments...  [32.621s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.088s]
Sorting trace points...  [1.22s]
Computing alignments...  [32.638s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.085s]
Sorting trace points...  [1.02s]
Computing alignments...  [32.646s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.25s]
Computing alignments...  [33.013s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.239s]
Computing alignments...  [32.683s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.245s]
Computing alignments...  [32.788s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.263s]
Computing alignments...  [33.803s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.348s]
Computing alignments...  [34.199s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.041s]
Computing alignments...  [34.094s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.282s]
Computing alignments...  [34.038s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.282s]
Computing alignments...  [34.018s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.277s]
Computing alignments...  [34.113s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.281s]
Computing alignments...  [34.175s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.177s]
Computing alignments...  [34.039s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [561.613s]
Deallocating reference...  [0.068s]
Loading reference sequences...  [33.748s]
Masking reference...  [31.262s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.146s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.523s]
Building query seed array...  [2.235s]
Computing hash join...  [5.265s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [80.252s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.576s]
Building query seed array...  [2.72s]
Computing hash join...  [5.211s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [49.429s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.272s]
Building query seed array...  [2.803s]
Computing hash join...  [5.15s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [45.48s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.131s]
Building query seed array...  [2.217s]
Computing hash join...  [5.19s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [39.707s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.164s]
Building query seed array...  [2.142s]
Computing hash join...  [5.004s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [40.04s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.175s]
Building query seed array...  [2.362s]
Computing hash join...  [5s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [32.479s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.127s]
Building query seed array...  [2.499s]
Computing hash join...  [4.914s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [35.503s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.075s]
Building query seed array...  [2.113s]
Computing hash join...  [4.956s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [30.965s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.13s]
Clearing query masking...  [1.727s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.48s]
Sorting trace points...  [1.301s]
Computing alignments...  [32.584s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.092s]
Sorting trace points...  [1.153s]
Computing alignments...  [32.547s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.221s]
Computing alignments...  [32.64s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.201s]
Computing alignments...  [32.565s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.241s]
Computing alignments...  [32.463s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.087s]
Sorting trace points...  [0.947s]
Computing alignments...  [32.982s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.038s]
Computing alignments...  [32.463s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.209s]
Computing alignments...  [32.627s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.268s]
Computing alignments...  [33.678s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.3s]
Computing alignments...  [34.041s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.307s]
Computing alignments...  [33.949s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.341s]
Computing alignments...  [33.898s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.223s]
Computing alignments...  [34.006s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [0.964s]
Computing alignments...  [34.014s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.323s]
Computing alignments...  [34.083s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [0.992s]
Computing alignments...  [33.856s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [559.145s]
Deallocating reference...  [0.07s]
Loading reference sequences...  [23.723s]
Masking reference...  [25.49s]
Initializing dictionary...  [0.063s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [26.377s]
Allocating buffers...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.09s]
Building query seed array...  [2.248s]
Computing hash join...  [4.337s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [63.858s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [10.058s]
Building query seed array...  [2.583s]
Computing hash join...  [4.303s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [43s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [11.162s]
Building query seed array...  [2.832s]
Computing hash join...  [4.394s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [36.859s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [8.32s]
Building query seed array...  [2.296s]
Computing hash join...  [4.436s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [33.098s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [8.243s]
Building query seed array...  [2.116s]
Computing hash join...  [4.137s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [32.892s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [9.926s]
Building query seed array...  [2.399s]
Computing hash join...  [4.125s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [26.835s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [10.741s]
Building query seed array...  [2.509s]
Computing hash join...  [4.167s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [29.463s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [8.235s]
Building query seed array...  [2.078s]
Computing hash join...  [4.185s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [25.947s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.106s]
Clearing query masking...  [1.68s]
Opening temporary output file...  [0.017s]
Computing alignments... Loading trace points...  [10.777s]
Sorting trace points...  [2.114s]
Computing alignments...  [52.357s]
Deallocating buffers...  [0.035s]
Loading trace points...  [0.123s]
Sorting trace points...  [2.05s]
Computing alignments...  [52.007s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.089s]
Sorting trace points...  [1.682s]
Computing alignments...  [52.463s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0.139s]
Sorting trace points...  [1.533s]
Computing alignments...  [51.931s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.129s]
Sorting trace points...  [2.137s]
Computing alignments...  [54.037s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.169s]
Sorting trace points...  [1.702s]
Computing alignments...  [54.071s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.179s]
Sorting trace points...  [2.141s]
Computing alignments...  [54.219s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0s]
Sorting trace points...  [2.041s]
Computing alignments...  [53.958s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0s]
 [452.348s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [0.099s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [2010.42s]
 [2010.42s]
Deallocating queries...  [0.064s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [4.208s]
 [5.466s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 18254.4s
Reported 2588751791 pairwise alignments, 2588751791 HSPs.
14655450 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C32_R1.fastp-trim.20230215.fq.gz complete: C32_R1.blastx.meganized.daa

Now MEGANizing C32_R1.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: C32_R1.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 80% 100% (300.4s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.4s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (4,741.1s)
Total reads:       14,655,450
With hits:          14,655,450 
Alignments:      2,580,156,545
Assig. Taxonomy:    13,338,487
Assig. SEED:           136,129
Assig. EGGNOG:          80,956
Assig. GTDB:           502,065
Assig. EC:           2,189,849
Assig. INTERPRO2GO:  1,389,062
MinSupport set to: 7327
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.4s)
Min-supp. changes:       4,855
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (13.6s)
Min-supp. changes:       3,927
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (41.6s)
Binning reads Syncing
100% (0.3s)
Class. Taxonomy:            95
Class. SEED:               532
Class. EGGNOG:           1,922
Class. GTDB:                31
Class. EC:               2,506
Class. INTERPRO2GO:      8,072
Total time:  5,107s
Peak memory: 31 of 195.3G
MEGANization of C32_R1.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C32_R2.fastp-trim.20230215.fq.gz...
0afe62fe6b54deeca29ded893abf7311  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C32_R2.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C32_R2.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.286s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.671s]
Opening the output file...  [0s]
Loading query sequences...  [83.095s]
Masking queries...  [21.018s]
Algorithm: Double-indexed
Building query histograms...  [20.069s]
Loading reference sequences...  [31.819s]
Masking reference...  [32.127s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.135s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.141s]
Building query seed array...  [2.301s]
Computing hash join...  [5.488s]
Masking low complexity seeds...  [0.278s]
Searching alignments...  [81.895s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.436s]
Building query seed array...  [2.668s]
Computing hash join...  [5.385s]
Masking low complexity seeds...  [0.276s]
Searching alignments...  [51.874s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.198s]
Building query seed array...  [2.832s]
Computing hash join...  [5.37s]
Masking low complexity seeds...  [0.296s]
Searching alignments...  [46.781s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.783s]
Building query seed array...  [2.223s]
Computing hash join...  [5.361s]
Masking low complexity seeds...  [0.284s]
Searching alignments...  [40.984s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.161s]
Building query seed array...  [2.042s]
Computing hash join...  [5.083s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [44.073s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.402s]
Building query seed array...  [2.335s]
Computing hash join...  [5.166s]
Masking low complexity seeds...  [0.281s]
Searching alignments...  [34.95s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.855s]
Building query seed array...  [2.535s]
Computing hash join...  [5.097s]
Masking low complexity seeds...  [0.274s]
Searching alignments...  [37.928s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.972s]
Building query seed array...  [2.091s]
Computing hash join...  [5.119s]
Masking low complexity seeds...  [0.275s]
Searching alignments...  [31.34s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.138s]
Clearing query masking...  [1.779s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.337s]
Sorting trace points...  [1.279s]
Computing alignments...  [32.199s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.085s]
Sorting trace points...  [1.212s]
Computing alignments...  [32.176s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.222s]
Computing alignments...  [32.594s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.09s]
Computing alignments...  [32.004s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.181s]
Computing alignments...  [32.268s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.4s]
Sorting trace points...  [0.95s]
Computing alignments...  [32.226s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.169s]
Computing alignments...  [31.869s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.077s]
Computing alignments...  [32.247s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.313s]
Computing alignments...  [34.274s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.104s]
Sorting trace points...  [1.218s]
Computing alignments...  [35.142s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.32s]
Computing alignments...  [35.089s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.358s]
Computing alignments...  [34.967s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.05s]
Sorting trace points...  [0.976s]
Computing alignments...  [34.993s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.313s]
Computing alignments...  [35.194s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.308s]
Computing alignments...  [35.101s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
Sorting trace points...  [1.295s]
Computing alignments...  [34.917s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [564.489s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [30.589s]
Masking reference...  [30.928s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.138s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [9.768s]
Building query seed array...  [2.325s]
Computing hash join...  [5.451s]
Masking low complexity seeds...  [0.287s]
Searching alignments...  [78.439s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.4s]
Building query seed array...  [2.728s]
Computing hash join...  [5.391s]
Masking low complexity seeds...  [0.291s]
Searching alignments...  [49.674s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.665s]
Building query seed array...  [2.955s]
Computing hash join...  [5.279s]
Masking low complexity seeds...  [0.272s]
Searching alignments...  [45.052s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.917s]
Building query seed array...  [2.261s]
Computing hash join...  [5.396s]
Masking low complexity seeds...  [0.288s]
Searching alignments...  [40.267s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.944s]
Building query seed array...  [2.057s]
Computing hash join...  [5.101s]
Masking low complexity seeds...  [0.272s]
Searching alignments...  [44.063s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.215s]
Building query seed array...  [2.374s]
Computing hash join...  [5.043s]
Masking low complexity seeds...  [0.268s]
Searching alignments...  [33.658s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.483s]
Building query seed array...  [2.453s]
Computing hash join...  [5.074s]
Masking low complexity seeds...  [0.278s]
Searching alignments...  [35.439s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.221s]
Building query seed array...  [2.153s]
Computing hash join...  [5.169s]
Masking low complexity seeds...  [0.265s]
Searching alignments...  [31.092s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.784s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.341s]
Sorting trace points...  [1.255s]
Computing alignments...  [32.214s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.113s]
Sorting trace points...  [1.197s]
Computing alignments...  [31.91s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.092s]
Sorting trace points...  [1.206s]
Computing alignments...  [32.395s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.048s]
Sorting trace points...  [0.93s]
Computing alignments...  [31.831s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.211s]
Computing alignments...  [32.146s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.206s]
Computing alignments...  [32.006s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.002s]
Sorting trace points...  [1.026s]
Computing alignments...  [31.697s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.179s]
Computing alignments...  [31.953s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.306s]
Computing alignments...  [34.096s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.319s]
Computing alignments...  [34.927s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.066s]
Computing alignments...  [34.734s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.777s]
Sorting trace points...  [1.195s]
Computing alignments...  [34.682s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.286s]
Computing alignments...  [34.621s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.259s]
Computing alignments...  [34.795s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.323s]
Computing alignments...  [34.747s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.259s]
Computing alignments...  [34.563s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [560.86s]
Deallocating reference...  [0.077s]
Loading reference sequences...  [29.45s]
Masking reference...  [30.922s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [33.126s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.389s]
Building query seed array...  [2.281s]
Computing hash join...  [5.379s]
Masking low complexity seeds...  [0.28s]
Searching alignments...  [81.504s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.347s]
Building query seed array...  [2.674s]
Computing hash join...  [5.413s]
Masking low complexity seeds...  [0.274s]
Searching alignments...  [51.473s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.593s]
Building query seed array...  [2.913s]
Computing hash join...  [5.334s]
Masking low complexity seeds...  [0.284s]
Searching alignments...  [46.949s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.091s]
Building query seed array...  [2.266s]
Computing hash join...  [5.364s]
Masking low complexity seeds...  [0.281s]
Searching alignments...  [40.756s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.236s]
Building query seed array...  [2.038s]
Computing hash join...  [5.138s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [44.351s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.316s]
Building query seed array...  [2.367s]
Computing hash join...  [5.056s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [35.233s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.048s]
Building query seed array...  [2.537s]
Computing hash join...  [5.069s]
Masking low complexity seeds...  [0.273s]
Searching alignments...  [38.533s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.152s]
Building query seed array...  [2.062s]
Computing hash join...  [5.117s]
Masking low complexity seeds...  [0.269s]
Searching alignments...  [32.367s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.13s]
Clearing query masking...  [1.685s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.386s]
Sorting trace points...  [1.273s]
Computing alignments...  [32.213s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.232s]
Computing alignments...  [32.06s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.063s]
Sorting trace points...  [0.966s]
Computing alignments...  [32.453s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.058s]
Sorting trace points...  [0.89s]
Computing alignments...  [31.874s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.223s]
Computing alignments...  [32.17s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.179s]
Computing alignments...  [32.091s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.195s]
Computing alignments...  [31.75s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.193s]
Computing alignments...  [31.99s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.341s]
Computing alignments...  [34.202s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.088s]
Sorting trace points...  [1.323s]
Computing alignments...  [35.046s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.294s]
Computing alignments...  [34.724s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.291s]
Computing alignments...  [34.775s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.288s]
Computing alignments...  [34.72s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.311s]
Computing alignments...  [34.859s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.288s]
Computing alignments...  [34.751s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
Sorting trace points...  [1.203s]
Computing alignments...  [34.627s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [561.416s]
Deallocating reference...  [0.065s]
Loading reference sequences...  [29.467s]
Masking reference...  [30.929s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [33.495s]
Allocating buffers...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [9.936s]
Building query seed array...  [2.218s]
Computing hash join...  [5.387s]
Masking low complexity seeds...  [0.284s]
Searching alignments...  [79.689s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.842s]
Building query seed array...  [2.652s]
Computing hash join...  [5.362s]
Masking low complexity seeds...  [0.277s]
Searching alignments...  [51.236s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.817s]
Building query seed array...  [2.802s]
Computing hash join...  [5.351s]
Masking low complexity seeds...  [0.281s]
Searching alignments...  [46.199s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.891s]
Building query seed array...  [2.279s]
Computing hash join...  [5.424s]
Masking low complexity seeds...  [0.282s]
Searching alignments...  [41.393s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.029s]
Building query seed array...  [2.079s]
Computing hash join...  [5.183s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [42.723s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.44s]
Building query seed array...  [2.448s]
Computing hash join...  [5.096s]
Masking low complexity seeds...  [0.259s]
Searching alignments...  [33.71s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.203s]
Building query seed array...  [2.564s]
Computing hash join...  [5.165s]
Masking low complexity seeds...  [0.28s]
Searching alignments...  [37.132s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.827s]
Building query seed array...  [2.07s]
Computing hash join...  [5.164s]
Masking low complexity seeds...  [0.273s]
Searching alignments...  [31.722s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.138s]
Clearing query masking...  [1.821s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.443s]
Sorting trace points...  [1.289s]
Computing alignments...  [32.31s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.162s]
Computing alignments...  [32.19s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.066s]
Computing alignments...  [32.516s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.07s]
Sorting trace points...  [0.913s]
Computing alignments...  [32.09s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.04s]
Sorting trace points...  [0.945s]
Computing alignments...  [32.307s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.25s]
Sorting trace points...  [1.075s]
Computing alignments...  [32.238s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.241s]
Computing alignments...  [31.945s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.125s]
Computing alignments...  [32.184s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.325s]
Computing alignments...  [34.324s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.066s]
Sorting trace points...  [0.975s]
Computing alignments...  [35.072s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.293s]
Computing alignments...  [34.961s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.058s]
Computing alignments...  [34.869s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.36s]
Computing alignments...  [34.72s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.362s]
Computing alignments...  [34.883s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.039s]
Sorting trace points...  [1.336s]
Computing alignments...  [34.712s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.297s]
Computing alignments...  [34.572s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [563.301s]
Deallocating reference...  [0.063s]
Loading reference sequences...  [29.551s]
Masking reference...  [32.135s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.336s]
Allocating buffers...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.401s]
Building query seed array...  [2.29s]
Computing hash join...  [5.337s]
Masking low complexity seeds...  [0.279s]
Searching alignments...  [78.029s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.335s]
Building query seed array...  [2.629s]
Computing hash join...  [5.277s]
Masking low complexity seeds...  [0.285s]
Searching alignments...  [51.825s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.692s]
Building query seed array...  [2.834s]
Computing hash join...  [5.316s]
Masking low complexity seeds...  [0.29s]
Searching alignments...  [44.932s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.235s]
Building query seed array...  [2.285s]
Computing hash join...  [5.328s]
Masking low complexity seeds...  [0.289s]
Searching alignments...  [39.6s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.389s]
Building query seed array...  [2.121s]
Computing hash join...  [5.069s]
Masking low complexity seeds...  [0.275s]
Searching alignments...  [42.604s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.107s]
Building query seed array...  [2.365s]
Computing hash join...  [5.153s]
Masking low complexity seeds...  [0.275s]
Searching alignments...  [33.436s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.237s]
Building query seed array...  [2.484s]
Computing hash join...  [5.038s]
Masking low complexity seeds...  [0.27s]
Searching alignments...  [36.248s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.242s]
Building query seed array...  [2.123s]
Computing hash join...  [5.073s]
Masking low complexity seeds...  [0.27s]
Searching alignments...  [31.878s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.131s]
Clearing query masking...  [1.788s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.409s]
Sorting trace points...  [1.292s]
Computing alignments...  [32.227s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.002s]
Computing alignments...  [31.991s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.08s]
Computing alignments...  [32.337s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.076s]
Sorting trace points...  [0.908s]
Computing alignments...  [31.827s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.059s]
Sorting trace points...  [0.926s]
Computing alignments...  [32.179s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.075s]
Sorting trace points...  [0.906s]
Computing alignments...  [32.098s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.175s]
Computing alignments...  [31.693s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.001s]
Sorting trace points...  [0.924s]
Computing alignments...  [31.959s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.278s]
Computing alignments...  [34.076s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.081s]
Sorting trace points...  [0.979s]
Computing alignments...  [34.961s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.104s]
Computing alignments...  [34.662s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.283s]
Computing alignments...  [34.663s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.316s]
Computing alignments...  [34.584s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.171s]
Computing alignments...  [34.685s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.297s]
Computing alignments...  [34.657s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.218s]
Computing alignments...  [34.438s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
 [558.413s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [29.535s]
Masking reference...  [30.852s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [33.52s]
Allocating buffers...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [9.955s]
Building query seed array...  [2.254s]
Computing hash join...  [5.305s]
Masking low complexity seeds...  [0.283s]
Searching alignments...  [77.105s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.475s]
Building query seed array...  [2.653s]
Computing hash join...  [5.337s]
Masking low complexity seeds...  [0.285s]
Searching alignments...  [50.425s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.647s]
Building query seed array...  [2.799s]
Computing hash join...  [5.255s]
Masking low complexity seeds...  [0.282s]
Searching alignments...  [45.675s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.313s]
Building query seed array...  [2.302s]
Computing hash join...  [5.317s]
Masking low complexity seeds...  [0.281s]
Searching alignments...  [40.687s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.11s]
Building query seed array...  [2.029s]
Computing hash join...  [5.11s]
Masking low complexity seeds...  [0.266s]
Searching alignments...  [40.89s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.8s]
Building query seed array...  [2.356s]
Computing hash join...  [5.128s]
Masking low complexity seeds...  [0.274s]
Searching alignments...  [33.941s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.326s]
Building query seed array...  [2.469s]
Computing hash join...  [5.058s]
Masking low complexity seeds...  [0.27s]
Searching alignments...  [35.329s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.997s]
Building query seed array...  [2.164s]
Computing hash join...  [5.062s]
Masking low complexity seeds...  [0.274s]
Searching alignments...  [30.517s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.756s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.366s]
Sorting trace points...  [1.276s]
Computing alignments...  [31.857s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.195s]
Computing alignments...  [31.701s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.186s]
Computing alignments...  [32.077s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.137s]
Computing alignments...  [31.557s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.203s]
Computing alignments...  [31.825s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.087s]
Sorting trace points...  [1.22s]
Computing alignments...  [31.797s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.084s]
Sorting trace points...  [1.187s]
Computing alignments...  [31.452s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.214s]
Computing alignments...  [31.724s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.289s]
Computing alignments...  [33.874s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.321s]
Computing alignments...  [34.717s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.317s]
Computing alignments...  [34.464s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.268s]
Computing alignments...  [34.521s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.319s]
Computing alignments...  [34.411s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.31s]
Computing alignments...  [34.579s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.192s]
Computing alignments...  [34.488s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.062s]
Computing alignments...  [34.29s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [556.783s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [29.513s]
Masking reference...  [32.084s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.814s]
Allocating buffers...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.382s]
Building query seed array...  [2.28s]
Computing hash join...  [5.44s]
Masking low complexity seeds...  [0.285s]
Searching alignments...  [80.7s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.227s]
Building query seed array...  [2.664s]
Computing hash join...  [5.3s]
Masking low complexity seeds...  [0.286s]
Searching alignments...  [51.429s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.239s]
Building query seed array...  [2.852s]
Computing hash join...  [5.193s]
Masking low complexity seeds...  [0.285s]
Searching alignments...  [45.921s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.366s]
Building query seed array...  [2.267s]
Computing hash join...  [5.295s]
Masking low complexity seeds...  [0.282s]
Searching alignments...  [39.478s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.868s]
Building query seed array...  [2.045s]
Computing hash join...  [5.086s]
Masking low complexity seeds...  [0.266s]
Searching alignments...  [43.609s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.797s]
Building query seed array...  [2.363s]
Computing hash join...  [5.11s]
Masking low complexity seeds...  [0.271s]
Searching alignments...  [34.027s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.987s]
Building query seed array...  [2.461s]
Computing hash join...  [5.027s]
Masking low complexity seeds...  [0.27s]
Searching alignments...  [37.084s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.044s]
Building query seed array...  [2.039s]
Computing hash join...  [5.134s]
Masking low complexity seeds...  [0.276s]
Searching alignments...  [31.851s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.778s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.327s]
Sorting trace points...  [1.282s]
Computing alignments...  [32.25s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.075s]
Sorting trace points...  [0.89s]
Computing alignments...  [31.952s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.286s]
Computing alignments...  [32.406s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.057s]
Sorting trace points...  [0.944s]
Computing alignments...  [31.924s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.205s]
Computing alignments...  [32.164s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.265s]
Computing alignments...  [32.148s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.041s]
Sorting trace points...  [0.973s]
Computing alignments...  [31.753s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.047s]
Sorting trace points...  [0.979s]
Computing alignments...  [32.026s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.578s]
Sorting trace points...  [1.006s]
Computing alignments...  [34.115s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.306s]
Computing alignments...  [34.964s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.364s]
Computing alignments...  [34.725s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.01s]
Computing alignments...  [34.823s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.313s]
Computing alignments...  [34.712s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.373s]
Sorting trace points...  [1.313s]
Computing alignments...  [34.835s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.288s]
Computing alignments...  [34.676s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [0.991s]
Computing alignments...  [34.638s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [560.836s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [33.275s]
Masking reference...  [30.84s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.91s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [9.9s]
Building query seed array...  [2.394s]
Computing hash join...  [5.313s]
Masking low complexity seeds...  [0.275s]
Searching alignments...  [79.83s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.11s]
Building query seed array...  [2.684s]
Computing hash join...  [5.279s]
Masking low complexity seeds...  [0.285s]
Searching alignments...  [51.568s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.416s]
Building query seed array...  [2.81s]
Computing hash join...  [5.39s]
Masking low complexity seeds...  [0.298s]
Searching alignments...  [46.224s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.682s]
Building query seed array...  [2.245s]
Computing hash join...  [5.242s]
Masking low complexity seeds...  [0.28s]
Searching alignments...  [40.985s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.318s]
Building query seed array...  [2.115s]
Computing hash join...  [5.117s]
Masking low complexity seeds...  [0.27s]
Searching alignments...  [43.126s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.136s]
Building query seed array...  [2.36s]
Computing hash join...  [5.044s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [34.507s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.143s]
Building query seed array...  [2.555s]
Computing hash join...  [5.092s]
Masking low complexity seeds...  [0.267s]
Searching alignments...  [36.481s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.912s]
Building query seed array...  [2.11s]
Computing hash join...  [5.136s]
Masking low complexity seeds...  [0.265s]
Searching alignments...  [32.369s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.128s]
Clearing query masking...  [1.794s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.312s]
Sorting trace points...  [1.285s]
Computing alignments...  [32.061s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.196s]
Computing alignments...  [32.025s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.148s]
Computing alignments...  [32.429s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.281s]
Computing alignments...  [31.858s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.178s]
Computing alignments...  [32.17s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.532s]
Sorting trace points...  [0.942s]
Computing alignments...  [32.056s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.207s]
Computing alignments...  [31.74s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.054s]
Sorting trace points...  [0.975s]
Computing alignments...  [31.993s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.107s]
Sorting trace points...  [1.295s]
Computing alignments...  [34.068s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.268s]
Computing alignments...  [34.895s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.355s]
Computing alignments...  [34.612s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.085s]
Sorting trace points...  [1.333s]
Computing alignments...  [34.646s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.261s]
Computing alignments...  [34.581s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.311s]
Computing alignments...  [34.747s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.347s]
Computing alignments...  [34.662s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.333s]
Computing alignments...  [34.522s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
 [560.79s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [30.882s]
Masking reference...  [30.825s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.381s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.32s]
Building query seed array...  [2.284s]
Computing hash join...  [5.351s]
Masking low complexity seeds...  [0.286s]
Searching alignments...  [78.801s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [11.949s]
Building query seed array...  [2.682s]
Computing hash join...  [5.229s]
Masking low complexity seeds...  [0.276s]
Searching alignments...  [50.837s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.874s]
Building query seed array...  [2.863s]
Computing hash join...  [5.336s]
Masking low complexity seeds...  [0.285s]
Searching alignments...  [44.927s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.059s]
Building query seed array...  [2.316s]
Computing hash join...  [5.351s]
Masking low complexity seeds...  [0.295s]
Searching alignments...  [39.48s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.416s]
Building query seed array...  [2.121s]
Computing hash join...  [5.012s]
Masking low complexity seeds...  [0.269s]
Searching alignments...  [43.738s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.442s]
Building query seed array...  [2.348s]
Computing hash join...  [5.063s]
Masking low complexity seeds...  [0.271s]
Searching alignments...  [33.495s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.218s]
Building query seed array...  [2.556s]
Computing hash join...  [5.05s]
Masking low complexity seeds...  [0.275s]
Searching alignments...  [36.521s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.754s]
Building query seed array...  [2.119s]
Computing hash join...  [5.122s]
Masking low complexity seeds...  [0.268s]
Searching alignments...  [31.177s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.783s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.345s]
Sorting trace points...  [1.283s]
Computing alignments...  [32.293s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.173s]
Computing alignments...  [32s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.042s]
Computing alignments...  [32.322s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.16s]
Computing alignments...  [31.776s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.173s]
Computing alignments...  [32.022s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.16s]
Computing alignments...  [31.957s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.087s]
Sorting trace points...  [1.19s]
Computing alignments...  [31.533s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.217s]
Computing alignments...  [31.95s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.101s]
Computing alignments...  [34.022s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.167s]
Computing alignments...  [34.842s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.196s]
Computing alignments...  [34.65s]
Deallocating buffers...  [0.016s]
Loading trace points...  [1.389s]
Sorting trace points...  [1.337s]
Computing alignments...  [34.72s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.33s]
Computing alignments...  [34.559s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.09s]
Sorting trace points...  [1.119s]
Computing alignments...  [34.689s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.165s]
Computing alignments...  [34.627s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.292s]
Computing alignments...  [34.368s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
 [560.264s]
Deallocating reference...  [0.065s]
Loading reference sequences...  [33.419s]
Masking reference...  [31.367s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.209s]
Allocating buffers...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.268s]
Building query seed array...  [2.256s]
Computing hash join...  [5.416s]
Masking low complexity seeds...  [0.288s]
Searching alignments...  [82.821s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.379s]
Building query seed array...  [2.62s]
Computing hash join...  [5.532s]
Masking low complexity seeds...  [0.282s]
Searching alignments...  [51.396s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.607s]
Building query seed array...  [2.773s]
Computing hash join...  [5.323s]
Masking low complexity seeds...  [0.282s]
Searching alignments...  [47.027s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.133s]
Building query seed array...  [2.229s]
Computing hash join...  [5.298s]
Masking low complexity seeds...  [0.274s]
Searching alignments...  [40.63s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.788s]
Building query seed array...  [2.05s]
Computing hash join...  [5.144s]
Masking low complexity seeds...  [0.273s]
Searching alignments...  [44.891s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.853s]
Building query seed array...  [2.459s]
Computing hash join...  [5.101s]
Masking low complexity seeds...  [0.279s]
Searching alignments...  [33.407s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.255s]
Building query seed array...  [2.567s]
Computing hash join...  [5.233s]
Masking low complexity seeds...  [0.268s]
Searching alignments...  [37.223s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.669s]
Building query seed array...  [2.051s]
Computing hash join...  [5.136s]
Masking low complexity seeds...  [0.272s]
Searching alignments...  [31.759s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.142s]
Clearing query masking...  [1.783s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.548s]
Sorting trace points...  [1.277s]
Computing alignments...  [31.974s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.082s]
Computing alignments...  [31.994s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.223s]
Computing alignments...  [32.461s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.193s]
Computing alignments...  [31.856s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.038s]
Sorting trace points...  [1.241s]
Computing alignments...  [32.211s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.109s]
Sorting trace points...  [1.243s]
Computing alignments...  [32.012s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.069s]
Sorting trace points...  [0.935s]
Computing alignments...  [31.707s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.23s]
Computing alignments...  [32.083s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.318s]
Computing alignments...  [34.087s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.294s]
Computing alignments...  [34.9s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.331s]
Computing alignments...  [34.76s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.291s]
Computing alignments...  [34.686s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.002s]
Computing alignments...  [34.517s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.308s]
Computing alignments...  [34.723s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.302s]
Computing alignments...  [34.595s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
Sorting trace points...  [1.144s]
Computing alignments...  [34.369s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [559.941s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [32.364s]
Masking reference...  [32.219s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.98s]
Allocating buffers...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [9.86s]
Building query seed array...  [2.32s]
Computing hash join...  [5.374s]
Masking low complexity seeds...  [0.279s]
Searching alignments...  [77.924s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.144s]
Building query seed array...  [2.682s]
Computing hash join...  [5.308s]
Masking low complexity seeds...  [0.291s]
Searching alignments...  [50.041s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.202s]
Building query seed array...  [2.854s]
Computing hash join...  [5.312s]
Masking low complexity seeds...  [0.286s]
Searching alignments...  [45.808s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.136s]
Building query seed array...  [2.226s]
Computing hash join...  [5.369s]
Masking low complexity seeds...  [0.285s]
Searching alignments...  [39.838s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.071s]
Building query seed array...  [2.109s]
Computing hash join...  [5.195s]
Masking low complexity seeds...  [0.274s]
Searching alignments...  [41.731s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.235s]
Building query seed array...  [2.381s]
Computing hash join...  [5.092s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [33.605s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.061s]
Building query seed array...  [2.584s]
Computing hash join...  [5.154s]
Masking low complexity seeds...  [0.271s]
Searching alignments...  [35.964s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.708s]
Building query seed array...  [2.031s]
Computing hash join...  [5.152s]
Masking low complexity seeds...  [0.278s]
Searching alignments...  [30.804s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.14s]
Clearing query masking...  [1.741s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.436s]
Sorting trace points...  [1.254s]
Computing alignments...  [32.259s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.08s]
Sorting trace points...  [0.922s]
Computing alignments...  [31.898s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.2s]
Computing alignments...  [32.315s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.236s]
Computing alignments...  [31.747s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.063s]
Sorting trace points...  [0.933s]
Computing alignments...  [32.041s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.189s]
Computing alignments...  [31.983s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.094s]
Sorting trace points...  [1.182s]
Computing alignments...  [31.658s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.157s]
Sorting trace points...  [1.209s]
Computing alignments...  [31.861s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.15s]
Computing alignments...  [34.101s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.191s]
Sorting trace points...  [1.009s]
Computing alignments...  [34.827s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.327s]
Computing alignments...  [34.565s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.358s]
Computing alignments...  [34.651s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.026s]
Computing alignments...  [34.594s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.351s]
Computing alignments...  [34.742s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.363s]
Sorting trace points...  [1.32s]
Computing alignments...  [34.501s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
Sorting trace points...  [1.329s]
Computing alignments...  [34.25s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [559.204s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [35.877s]
Masking reference...  [30.865s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.716s]
Allocating buffers...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.513s]
Building query seed array...  [2.26s]
Computing hash join...  [5.416s]
Masking low complexity seeds...  [0.286s]
Searching alignments...  [80.37s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.082s]
Building query seed array...  [2.665s]
Computing hash join...  [5.413s]
Masking low complexity seeds...  [0.288s]
Searching alignments...  [51.289s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.395s]
Building query seed array...  [2.804s]
Computing hash join...  [5.312s]
Masking low complexity seeds...  [0.286s]
Searching alignments...  [45.617s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.81s]
Building query seed array...  [2.259s]
Computing hash join...  [5.307s]
Masking low complexity seeds...  [0.284s]
Searching alignments...  [40.088s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.138s]
Building query seed array...  [2.015s]
Computing hash join...  [5.15s]
Masking low complexity seeds...  [0.274s]
Searching alignments...  [43.804s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.095s]
Building query seed array...  [2.398s]
Computing hash join...  [5.115s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [33.729s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.887s]
Building query seed array...  [2.429s]
Computing hash join...  [5.086s]
Masking low complexity seeds...  [0.259s]
Searching alignments...  [37.559s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.854s]
Building query seed array...  [2.082s]
Computing hash join...  [5.143s]
Masking low complexity seeds...  [0.27s]
Searching alignments...  [31.261s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.764s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.329s]
Sorting trace points...  [1.3s]
Computing alignments...  [32.288s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.062s]
Sorting trace points...  [0.936s]
Computing alignments...  [32.045s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.242s]
Computing alignments...  [32.272s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.084s]
Sorting trace points...  [1.021s]
Computing alignments...  [31.826s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.231s]
Computing alignments...  [32.05s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.062s]
Sorting trace points...  [0.898s]
Computing alignments...  [31.973s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.133s]
Computing alignments...  [31.693s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.19s]
Computing alignments...  [31.963s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.196s]
Computing alignments...  [34.08s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.327s]
Computing alignments...  [34.948s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.31s]
Computing alignments...  [34.684s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.279s]
Computing alignments...  [34.676s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.04s]
Sorting trace points...  [1.018s]
Computing alignments...  [34.609s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.373s]
Computing alignments...  [34.7s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.04s]
Sorting trace points...  [1.358s]
Computing alignments...  [34.642s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
Sorting trace points...  [1.322s]
Computing alignments...  [34.403s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [559.357s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [31.944s]
Masking reference...  [30.868s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.732s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.008s]
Building query seed array...  [2.328s]
Computing hash join...  [5.257s]
Masking low complexity seeds...  [0.275s]
Searching alignments...  [80.365s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.641s]
Building query seed array...  [2.578s]
Computing hash join...  [5.433s]
Masking low complexity seeds...  [0.279s]
Searching alignments...  [51.484s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.116s]
Building query seed array...  [2.86s]
Computing hash join...  [5.318s]
Masking low complexity seeds...  [0.283s]
Searching alignments...  [47.104s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.393s]
Building query seed array...  [2.266s]
Computing hash join...  [5.334s]
Masking low complexity seeds...  [0.278s]
Searching alignments...  [42.269s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.01s]
Building query seed array...  [2.052s]
Computing hash join...  [5.149s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [44.207s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.39s]
Building query seed array...  [2.41s]
Computing hash join...  [5.136s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [34.185s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.22s]
Building query seed array...  [2.539s]
Computing hash join...  [5.117s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [37.333s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.395s]
Building query seed array...  [2.056s]
Computing hash join...  [5.131s]
Masking low complexity seeds...  [0.272s]
Searching alignments...  [32.332s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.132s]
Clearing query masking...  [1.723s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.344s]
Sorting trace points...  [1.287s]
Computing alignments...  [32.134s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.199s]
Computing alignments...  [31.906s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.279s]
Computing alignments...  [32.24s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.216s]
Sorting trace points...  [1.073s]
Computing alignments...  [31.754s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.192s]
Computing alignments...  [32.059s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.179s]
Computing alignments...  [31.943s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.179s]
Computing alignments...  [31.61s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.19s]
Computing alignments...  [31.957s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.16s]
Computing alignments...  [34.075s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.373s]
Computing alignments...  [34.828s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.338s]
Computing alignments...  [34.52s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.313s]
Computing alignments...  [34.537s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.312s]
Computing alignments...  [34.458s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.329s]
Computing alignments...  [34.708s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.27s]
Computing alignments...  [34.503s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.228s]
Computing alignments...  [34.278s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [559.077s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [23.924s]
Masking reference...  [26.02s]
Initializing dictionary...  [0.062s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [26.266s]
Allocating buffers...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.157s]
Building query seed array...  [2.323s]
Computing hash join...  [4.514s]
Masking low complexity seeds...  [0.274s]
Searching alignments...  [61.541s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [10.43s]
Building query seed array...  [2.663s]
Computing hash join...  [4.459s]
Masking low complexity seeds...  [0.272s]
Searching alignments...  [40.362s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [10.698s]
Building query seed array...  [2.82s]
Computing hash join...  [4.409s]
Masking low complexity seeds...  [0.276s]
Searching alignments...  [37.712s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [8.019s]
Building query seed array...  [2.274s]
Computing hash join...  [4.426s]
Masking low complexity seeds...  [0.275s]
Searching alignments...  [32.69s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [8.034s]
Building query seed array...  [2.098s]
Computing hash join...  [4.272s]
Masking low complexity seeds...  [0.249s]
Searching alignments...  [35.098s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [9.492s]
Building query seed array...  [2.444s]
Computing hash join...  [4.256s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [28.572s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [10.782s]
Building query seed array...  [2.54s]
Computing hash join...  [4.32s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [29.653s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [7.952s]
Building query seed array...  [2.043s]
Computing hash join...  [4.232s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [25.717s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.105s]
Clearing query masking...  [1.774s]
Opening temporary output file...  [0.022s]
Computing alignments... Loading trace points...  [10.621s]
Sorting trace points...  [1.656s]
Computing alignments...  [51.043s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.129s]
Sorting trace points...  [2.04s]
Computing alignments...  [51.192s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.102s]
Sorting trace points...  [1.913s]
Computing alignments...  [51.187s]
Deallocating buffers...  [0.034s]
Loading trace points...  [0.185s]
Sorting trace points...  [2.002s]
Computing alignments...  [50.847s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.122s]
Sorting trace points...  [1.913s]
Computing alignments...  [55.158s]
Deallocating buffers...  [0.038s]
Loading trace points...  [0.166s]
Sorting trace points...  [2.147s]
Computing alignments...  [55.218s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.154s]
Sorting trace points...  [2.019s]
Computing alignments...  [55.172s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0s]
Sorting trace points...  [1.776s]
Computing alignments...  [55.234s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0s]
 [452.326s]
Deallocating reference...  [0.049s]
Loading reference sequences...  [0.08s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [1989.93s]
 [1989.93s]
Deallocating queries...  [0.068s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [4.159s]
 [5.59s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 18364.1s
Reported 2510906925 pairwise alignments, 2510906925 HSPs.
15067145 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/C32_R2.fastp-trim.20230215.fq.gz complete: C32_R2.blastx.meganized.daa

Now MEGANizing C32_R2.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: C32_R2.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 80% 100% (294.9s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.4s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (4,630.2s)
Total reads:       15,067,145
With hits:          15,067,145 
Alignments:      2,503,673,872
Assig. Taxonomy:    13,654,683
Assig. SEED:           131,269
Assig. EGGNOG:          79,742
Assig. GTDB:           479,160
Assig. EC:           2,235,453
Assig. INTERPRO2GO:  1,371,499
MinSupport set to: 7533
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.4s)
Min-supp. changes:       4,962
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (11.8s)
Min-supp. changes:       4,026
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (35.7s)
Binning reads Syncing
100% (0.4s)
Class. Taxonomy:           100
Class. SEED:               531
Class. EGGNOG:           1,917
Class. GTDB:                23
Class. EC:               2,488
Class. INTERPRO2GO:      8,105
Total time:  4,983s
Peak memory: 36.1 of 195.3G
MEGANization of C32_R2.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E10_R1.fastp-trim.20230215.fq.gz...
6177d40dceb78a6b0988e282e714ca07  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E10_R1.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E10_R1.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.317s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.699s]
Opening the output file...  [0s]
Loading query sequences...  [88.625s]
Masking queries...  [22.783s]
Algorithm: Double-indexed
Building query histograms...  [21.864s]
Loading reference sequences...  [29.201s]
Masking reference...  [32.142s]
Initializing dictionary...  [0.08s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.622s]
Allocating buffers...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.506s]
Building query seed array...  [2.471s]
Computing hash join...  [5.374s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [90.346s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.11s]
Building query seed array...  [2.904s]
Computing hash join...  [5.267s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [57.326s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.44s]
Building query seed array...  [2.966s]
Computing hash join...  [5.285s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [50.143s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.979s]
Building query seed array...  [2.437s]
Computing hash join...  [5.258s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [45.904s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.052s]
Building query seed array...  [2.248s]
Computing hash join...  [4.972s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [45.603s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.442s]
Building query seed array...  [2.542s]
Computing hash join...  [5.053s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [37.028s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.126s]
Building query seed array...  [2.696s]
Computing hash join...  [5.078s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [39.979s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.857s]
Building query seed array...  [2.288s]
Computing hash join...  [4.983s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [34.918s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.127s]
Clearing query masking...  [1.81s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.384s]
Sorting trace points...  [1.485s]
Computing alignments...  [37.255s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.413s]
Computing alignments...  [37.062s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.18s]
Computing alignments...  [36.777s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.609s]
Sorting trace points...  [1.095s]
Computing alignments...  [36.723s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.291s]
Computing alignments...  [36.557s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.405s]
Computing alignments...  [36.963s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.381s]
Computing alignments...  [36.601s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.135s]
Computing alignments...  [36.346s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.444s]
Computing alignments...  [37.44s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.183s]
Computing alignments...  [38.431s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.466s]
Computing alignments...  [38.561s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.443s]
Computing alignments...  [38.375s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.394s]
Computing alignments...  [38.322s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.43s]
Computing alignments...  [38.488s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.073s]
Computing alignments...  [38.375s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.121s]
Computing alignments...  [38.105s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [630.492s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.503s]
Masking reference...  [30.878s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [33.034s]
Allocating buffers...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.596s]
Building query seed array...  [2.518s]
Computing hash join...  [5.219s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [88.567s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.164s]
Building query seed array...  [2.833s]
Computing hash join...  [5.224s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [57.448s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.986s]
Building query seed array...  [3.036s]
Computing hash join...  [5.176s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [51.45s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.755s]
Building query seed array...  [2.45s]
Computing hash join...  [5.078s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [46.294s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.957s]
Building query seed array...  [2.264s]
Computing hash join...  [5.005s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [45.296s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.429s]
Building query seed array...  [2.547s]
Computing hash join...  [4.857s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [36.539s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.991s]
Building query seed array...  [2.677s]
Computing hash join...  [4.908s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [39.65s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.881s]
Building query seed array...  [2.234s]
Computing hash join...  [4.934s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [34.63s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.131s]
Clearing query masking...  [1.865s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [7.169s]
Sorting trace points...  [1.47s]
Computing alignments...  [37.007s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.441s]
Computing alignments...  [36.687s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.099s]
Sorting trace points...  [1.209s]
Computing alignments...  [36.598s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.372s]
Computing alignments...  [36.562s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.732s]
Computing alignments...  [36.439s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.299s]
Computing alignments...  [36.698s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.025s]
Computing alignments...  [36.326s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.393s]
Computing alignments...  [36.206s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.413s]
Computing alignments...  [37.328s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.306s]
Computing alignments...  [38.289s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.495s]
Computing alignments...  [38.478s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.465s]
Computing alignments...  [38.235s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.464s]
Computing alignments...  [38.322s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.525s]
Computing alignments...  [38.431s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.463s]
Computing alignments...  [38.38s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.453s]
Computing alignments...  [38.133s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [629.143s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [29.716s]
Masking reference...  [32.121s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.193s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.429s]
Building query seed array...  [2.52s]
Computing hash join...  [5.215s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [88.515s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.599s]
Building query seed array...  [2.827s]
Computing hash join...  [5.289s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [58.846s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.156s]
Building query seed array...  [2.98s]
Computing hash join...  [5.194s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [52.066s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.01s]
Building query seed array...  [2.441s]
Computing hash join...  [5.135s]
Masking low complexity seeds...  [0.486s]
Searching alignments...  [44.751s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.958s]
Building query seed array...  [2.282s]
Computing hash join...  [4.925s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [46.085s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.319s]
Building query seed array...  [2.613s]
Computing hash join...  [4.957s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [35.991s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.371s]
Building query seed array...  [2.74s]
Computing hash join...  [5.012s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [40.219s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.813s]
Building query seed array...  [2.184s]
Computing hash join...  [4.957s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [34.748s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.14s]
Clearing query masking...  [1.88s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.411s]
Sorting trace points...  [1.49s]
Computing alignments...  [37.043s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.36s]
Computing alignments...  [36.851s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.166s]
Computing alignments...  [36.709s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.085s]
Sorting trace points...  [1.102s]
Computing alignments...  [36.572s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.42s]
Computing alignments...  [36.49s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.315s]
Computing alignments...  [36.898s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.387s]
Computing alignments...  [36.626s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.036s]
Sorting trace points...  [1.147s]
Computing alignments...  [36.488s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.22s]
Computing alignments...  [37.607s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.431s]
Computing alignments...  [38.4s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.474s]
Computing alignments...  [38.532s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.102s]
Sorting trace points...  [1.458s]
Computing alignments...  [38.414s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.502s]
Computing alignments...  [38.424s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.443s]
Computing alignments...  [38.532s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.089s]
Sorting trace points...  [1.373s]
Computing alignments...  [38.409s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.423s]
Computing alignments...  [38.092s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [630.495s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [29.502s]
Masking reference...  [30.958s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.07s]
Allocating buffers...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.18s]
Building query seed array...  [2.49s]
Computing hash join...  [5.217s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [87.127s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.17s]
Building query seed array...  [2.895s]
Computing hash join...  [5.337s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [56.973s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.723s]
Building query seed array...  [3.012s]
Computing hash join...  [5.236s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [50.327s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.959s]
Building query seed array...  [2.563s]
Computing hash join...  [5.178s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [44.82s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.317s]
Building query seed array...  [2.234s]
Computing hash join...  [5.018s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [45.953s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.721s]
Building query seed array...  [2.596s]
Computing hash join...  [5.006s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [37.023s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.521s]
Building query seed array...  [2.659s]
Computing hash join...  [5.025s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [40.499s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.064s]
Building query seed array...  [2.201s]
Computing hash join...  [4.989s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [34.31s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.809s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.31s]
Sorting trace points...  [1.506s]
Computing alignments...  [37.17s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.418s]
Computing alignments...  [36.885s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.04s]
Computing alignments...  [36.659s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.035s]
Computing alignments...  [36.769s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.454s]
Computing alignments...  [36.574s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.406s]
Computing alignments...  [36.941s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.396s]
Computing alignments...  [36.665s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.055s]
Computing alignments...  [36.472s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.09s]
Sorting trace points...  [1.102s]
Computing alignments...  [37.513s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.167s]
Computing alignments...  [38.427s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.339s]
Computing alignments...  [38.522s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.112s]
Sorting trace points...  [1.131s]
Computing alignments...  [38.339s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.307s]
Computing alignments...  [38.362s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.1s]
Sorting trace points...  [1.379s]
Computing alignments...  [38.49s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.111s]
Computing alignments...  [38.306s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.444s]
Computing alignments...  [38.05s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [629.556s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [244.245s]
Masking reference...  [30.989s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.739s]
Allocating buffers...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.171s]
Building query seed array...  [2.424s]
Computing hash join...  [5.223s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [87.235s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.625s]
Building query seed array...  [2.838s]
Computing hash join...  [5.184s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [56.598s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.596s]
Building query seed array...  [3.034s]
Computing hash join...  [5.242s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [50.857s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.768s]
Building query seed array...  [2.519s]
Computing hash join...  [5.151s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [44.112s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.082s]
Building query seed array...  [2.201s]
Computing hash join...  [5.057s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [44.775s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.15s]
Building query seed array...  [2.592s]
Computing hash join...  [4.968s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [35.759s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.22s]
Building query seed array...  [2.775s]
Computing hash join...  [4.994s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [39.208s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.884s]
Building query seed array...  [2.196s]
Computing hash join...  [4.882s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [34.657s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.135s]
Clearing query masking...  [1.868s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [7.31s]
Sorting trace points...  [1.448s]
Computing alignments...  [36.794s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.07s]
Computing alignments...  [36.579s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.099s]
Sorting trace points...  [1.412s]
Computing alignments...  [36.559s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.072s]
Computing alignments...  [36.506s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.091s]
Computing alignments...  [36.254s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.037s]
Sorting trace points...  [1.389s]
Computing alignments...  [36.715s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.394s]
Computing alignments...  [36.457s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.365s]
Computing alignments...  [36.178s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.395s]
Computing alignments...  [37.276s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.528s]
Computing alignments...  [38.266s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.503s]
Computing alignments...  [38.419s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.458s]
Computing alignments...  [38.147s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.441s]
Computing alignments...  [38.149s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.183s]
Computing alignments...  [38.388s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.51s]
Computing alignments...  [38.187s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.45s]
Computing alignments...  [38.054s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [627.173s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [29.55s]
Masking reference...  [30.835s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.059s]
Allocating buffers...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.387s]
Building query seed array...  [2.5s]
Computing hash join...  [5.235s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [86.677s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.437s]
Building query seed array...  [2.786s]
Computing hash join...  [5.217s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [55.552s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.367s]
Building query seed array...  [3.026s]
Computing hash join...  [5.164s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [48.618s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.621s]
Building query seed array...  [2.439s]
Computing hash join...  [5.191s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [43.577s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.936s]
Building query seed array...  [2.222s]
Computing hash join...  [4.991s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [44.066s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.088s]
Building query seed array...  [2.585s]
Computing hash join...  [4.904s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [35.42s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.243s]
Building query seed array...  [2.77s]
Computing hash join...  [4.992s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [38.882s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.844s]
Building query seed array...  [2.139s]
Computing hash join...  [4.978s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [33.436s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.143s]
Clearing query masking...  [1.856s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.189s]
Sorting trace points...  [1.433s]
Computing alignments...  [36.907s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.356s]
Computing alignments...  [36.664s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.386s]
Computing alignments...  [36.485s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.362s]
Computing alignments...  [36.472s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.392s]
Computing alignments...  [36.409s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.025s]
Computing alignments...  [36.834s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.416s]
Computing alignments...  [36.539s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.397s]
Computing alignments...  [36.394s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.571s]
Sorting trace points...  [1.445s]
Computing alignments...  [37.434s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.163s]
Computing alignments...  [38.364s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.32s]
Computing alignments...  [38.406s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.349s]
Sorting trace points...  [1.308s]
Computing alignments...  [38.225s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.483s]
Computing alignments...  [38.347s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.409s]
Computing alignments...  [38.449s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.555s]
Sorting trace points...  [1.491s]
Computing alignments...  [38.428s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.47s]
Computing alignments...  [38.144s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
 [630.072s]
Deallocating reference...  [0.074s]
Loading reference sequences...  [29.623s]
Masking reference...  [31.559s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.315s]
Allocating buffers...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.378s]
Building query seed array...  [2.45s]
Computing hash join...  [5.194s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [89.454s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.046s]
Building query seed array...  [2.84s]
Computing hash join...  [5.253s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [56.385s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.29s]
Building query seed array...  [3.001s]
Computing hash join...  [5.238s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [51.239s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.342s]
Building query seed array...  [2.488s]
Computing hash join...  [5.134s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [45.556s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.189s]
Building query seed array...  [2.274s]
Computing hash join...  [4.981s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [45.446s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12s]
Building query seed array...  [2.495s]
Computing hash join...  [5.006s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [36.915s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.682s]
Building query seed array...  [2.641s]
Computing hash join...  [5.014s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [39.501s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.879s]
Building query seed array...  [2.243s]
Computing hash join...  [5.019s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [34.717s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.137s]
Clearing query masking...  [1.875s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.283s]
Sorting trace points...  [1.467s]
Computing alignments...  [37.261s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.04s]
Sorting trace points...  [1.394s]
Computing alignments...  [36.994s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.393s]
Computing alignments...  [36.794s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.382s]
Computing alignments...  [36.623s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.402s]
Computing alignments...  [36.612s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.178s]
Computing alignments...  [37.059s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.258s]
Computing alignments...  [36.696s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.372s]
Computing alignments...  [36.6s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.239s]
Computing alignments...  [37.613s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.488s]
Computing alignments...  [38.455s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.409s]
Computing alignments...  [38.628s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.202s]
Computing alignments...  [38.495s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.474s]
Computing alignments...  [38.45s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.487s]
Computing alignments...  [38.593s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.107s]
Computing alignments...  [38.529s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.243s]
Computing alignments...  [38.23s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
 [631.627s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [29.357s]
Masking reference...  [30.87s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.482s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.009s]
Building query seed array...  [2.406s]
Computing hash join...  [5.126s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [89.192s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.441s]
Building query seed array...  [2.892s]
Computing hash join...  [5.356s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [58.493s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [14.3s]
Building query seed array...  [3.034s]
Computing hash join...  [5.227s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [50.32s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.863s]
Building query seed array...  [2.459s]
Computing hash join...  [5.151s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [46.047s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.044s]
Building query seed array...  [2.243s]
Computing hash join...  [4.989s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [45.846s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.351s]
Building query seed array...  [2.605s]
Computing hash join...  [5.005s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [36.272s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.429s]
Building query seed array...  [2.711s]
Computing hash join...  [5.011s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [40.146s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.073s]
Building query seed array...  [2.214s]
Computing hash join...  [5.05s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [35.189s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.128s]
Clearing query masking...  [1.859s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.471s]
Sorting trace points...  [1.368s]
Computing alignments...  [37.15s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.405s]
Computing alignments...  [36.899s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.609s]
Computing alignments...  [36.857s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.043s]
Computing alignments...  [36.712s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.421s]
Computing alignments...  [36.579s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.195s]
Computing alignments...  [36.943s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.368s]
Computing alignments...  [36.683s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.369s]
Computing alignments...  [36.424s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.274s]
Computing alignments...  [37.555s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.139s]
Computing alignments...  [38.464s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.479s]
Computing alignments...  [38.618s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.087s]
Sorting trace points...  [1.452s]
Computing alignments...  [38.41s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.339s]
Computing alignments...  [38.525s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.434s]
Computing alignments...  [38.504s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.091s]
Computing alignments...  [38.433s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0s]
Sorting trace points...  [1.438s]
Computing alignments...  [38.292s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [631.275s]
Deallocating reference...  [0.064s]
Loading reference sequences...  [30.181s]
Masking reference...  [32.108s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.347s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.516s]
Building query seed array...  [2.443s]
Computing hash join...  [5.2s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [89.757s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.734s]
Building query seed array...  [2.867s]
Computing hash join...  [5.111s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [56.664s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.049s]
Building query seed array...  [3s]
Computing hash join...  [5.199s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [50.015s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.165s]
Building query seed array...  [2.522s]
Computing hash join...  [5.228s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [44.186s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.243s]
Building query seed array...  [2.234s]
Computing hash join...  [4.989s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [45.422s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.479s]
Building query seed array...  [2.557s]
Computing hash join...  [4.983s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [35.905s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.536s]
Building query seed array...  [2.764s]
Computing hash join...  [4.926s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [39.739s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.964s]
Building query seed array...  [2.137s]
Computing hash join...  [4.989s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [34.428s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.853s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.614s]
Sorting trace points...  [1.48s]
Computing alignments...  [37.186s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.36s]
Computing alignments...  [36.962s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.111s]
Sorting trace points...  [1.395s]
Computing alignments...  [36.655s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.085s]
Sorting trace points...  [1.384s]
Computing alignments...  [36.562s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.022s]
Computing alignments...  [36.575s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.454s]
Computing alignments...  [37.016s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.428s]
Computing alignments...  [36.722s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.29s]
Computing alignments...  [36.571s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.444s]
Computing alignments...  [37.636s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.261s]
Computing alignments...  [38.569s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.474s]
Computing alignments...  [38.806s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.423s]
Computing alignments...  [38.441s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.516s]
Computing alignments...  [38.418s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.47s]
Computing alignments...  [38.64s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.093s]
Sorting trace points...  [1.296s]
Computing alignments...  [38.687s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
Sorting trace points...  [1.461s]
Computing alignments...  [38.369s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [632.946s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [29.402s]
Masking reference...  [32.127s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [31.992s]
Allocating buffers...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.441s]
Building query seed array...  [2.415s]
Computing hash join...  [5.161s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [89.054s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.182s]
Building query seed array...  [2.832s]
Computing hash join...  [5.291s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [56.452s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.327s]
Building query seed array...  [3.021s]
Computing hash join...  [5.154s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [52.808s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.895s]
Building query seed array...  [2.454s]
Computing hash join...  [5.213s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [45.104s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.199s]
Building query seed array...  [2.171s]
Computing hash join...  [4.984s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [46.08s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.384s]
Building query seed array...  [2.578s]
Computing hash join...  [5.035s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [36.373s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.386s]
Building query seed array...  [2.741s]
Computing hash join...  [5.088s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [39.825s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.319s]
Building query seed array...  [2.215s]
Computing hash join...  [4.956s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [36.027s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.127s]
Clearing query masking...  [1.869s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.267s]
Sorting trace points...  [1.469s]
Computing alignments...  [36.986s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.096s]
Computing alignments...  [36.906s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.085s]
Sorting trace points...  [1.231s]
Computing alignments...  [36.675s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.336s]
Computing alignments...  [36.652s]
Deallocating buffers...  [0.022s]
Loading trace points...  [1.053s]
Sorting trace points...  [1.413s]
Computing alignments...  [36.541s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.449s]
Computing alignments...  [36.917s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.127s]
Computing alignments...  [36.576s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.347s]
Computing alignments...  [36.447s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.347s]
Computing alignments...  [37.477s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.424s]
Computing alignments...  [38.33s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.039s]
Sorting trace points...  [1.431s]
Computing alignments...  [38.528s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.467s]
Computing alignments...  [38.307s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.094s]
Sorting trace points...  [1.409s]
Computing alignments...  [38.381s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.487s]
Computing alignments...  [38.446s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.318s]
Computing alignments...  [38.352s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.156s]
Computing alignments...  [38.139s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [630.754s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [29.641s]
Masking reference...  [30.842s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.542s]
Allocating buffers...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.33s]
Building query seed array...  [2.478s]
Computing hash join...  [5.21s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [87.08s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.281s]
Building query seed array...  [2.922s]
Computing hash join...  [5.3s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [58.349s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.651s]
Building query seed array...  [2.958s]
Computing hash join...  [5.233s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [50.773s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.151s]
Building query seed array...  [2.427s]
Computing hash join...  [5.143s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [45.461s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.099s]
Building query seed array...  [2.219s]
Computing hash join...  [5.028s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [44.872s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.939s]
Building query seed array...  [2.551s]
Computing hash join...  [5.231s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [35.67s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.141s]
Building query seed array...  [2.818s]
Computing hash join...  [5.074s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [39.011s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.103s]
Building query seed array...  [2.264s]
Computing hash join...  [4.998s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [34.345s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.131s]
Clearing query masking...  [1.847s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [7.201s]
Sorting trace points...  [1.477s]
Computing alignments...  [37.153s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.393s]
Computing alignments...  [36.813s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.684s]
Sorting trace points...  [1.449s]
Computing alignments...  [36.583s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.403s]
Computing alignments...  [36.58s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.38s]
Computing alignments...  [36.441s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.376s]
Computing alignments...  [36.816s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.1s]
Sorting trace points...  [1.384s]
Computing alignments...  [36.501s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.413s]
Computing alignments...  [36.329s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.265s]
Computing alignments...  [37.472s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.26s]
Computing alignments...  [38.399s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.225s]
Sorting trace points...  [1.463s]
Computing alignments...  [38.553s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.213s]
Computing alignments...  [38.333s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.457s]
Computing alignments...  [38.299s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.088s]
Computing alignments...  [38.371s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.491s]
Computing alignments...  [38.323s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.442s]
Computing alignments...  [38.035s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [630.251s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [29.655s]
Masking reference...  [30.868s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.005s]
Allocating buffers...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.078s]
Building query seed array...  [2.437s]
Computing hash join...  [5.228s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [89.84s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [11.923s]
Building query seed array...  [2.802s]
Computing hash join...  [5.224s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [57.92s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.847s]
Building query seed array...  [2.921s]
Computing hash join...  [5.153s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [50.487s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.772s]
Building query seed array...  [2.473s]
Computing hash join...  [5.116s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [43.574s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.794s]
Building query seed array...  [2.274s]
Computing hash join...  [5.01s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [45.82s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.609s]
Building query seed array...  [2.587s]
Computing hash join...  [4.953s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [35.82s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.489s]
Building query seed array...  [2.73s]
Computing hash join...  [5.018s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [39.984s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.925s]
Building query seed array...  [2.2s]
Computing hash join...  [4.895s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [34.928s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.137s]
Clearing query masking...  [1.99s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [8.086s]
Sorting trace points...  [1.472s]
Computing alignments...  [37.185s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.866s]
Sorting trace points...  [1.337s]
Computing alignments...  [36.946s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.414s]
Computing alignments...  [36.766s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.373s]
Computing alignments...  [36.742s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.085s]
Sorting trace points...  [1.384s]
Computing alignments...  [36.591s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.398s]
Computing alignments...  [37.07s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.258s]
Computing alignments...  [36.72s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.039s]
Sorting trace points...  [1.338s]
Computing alignments...  [36.623s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.457s]
Computing alignments...  [37.654s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.21s]
Computing alignments...  [38.573s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.042s]
Sorting trace points...  [1.389s]
Computing alignments...  [38.718s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.479s]
Computing alignments...  [38.529s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.112s]
Computing alignments...  [38.549s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.115s]
Sorting trace points...  [1.264s]
Computing alignments...  [38.626s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.429s]
Computing alignments...  [38.531s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.45s]
Computing alignments...  [38.317s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [634.096s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [30.048s]
Masking reference...  [32.113s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.248s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.278s]
Building query seed array...  [2.399s]
Computing hash join...  [5.254s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [89.059s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.411s]
Building query seed array...  [2.915s]
Computing hash join...  [5.317s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [57.182s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.55s]
Building query seed array...  [2.957s]
Computing hash join...  [5.251s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [52.397s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.974s]
Building query seed array...  [2.426s]
Computing hash join...  [5.206s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [45.745s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.089s]
Building query seed array...  [2.17s]
Computing hash join...  [4.998s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [45.122s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.361s]
Building query seed array...  [2.634s]
Computing hash join...  [4.928s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [36.485s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.276s]
Building query seed array...  [2.75s]
Computing hash join...  [5.045s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [39.958s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.201s]
Building query seed array...  [2.181s]
Computing hash join...  [5.003s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [35.197s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.103s]
Clearing query masking...  [1.918s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.285s]
Sorting trace points...  [1.491s]
Computing alignments...  [36.92s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.391s]
Computing alignments...  [36.771s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.389s]
Computing alignments...  [36.658s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.409s]
Computing alignments...  [36.589s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.607s]
Sorting trace points...  [1.463s]
Computing alignments...  [36.532s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.038s]
Sorting trace points...  [1.126s]
Computing alignments...  [36.984s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.143s]
Computing alignments...  [36.619s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.368s]
Computing alignments...  [36.559s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.081s]
Computing alignments...  [37.543s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.458s]
Computing alignments...  [38.298s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.48s]
Computing alignments...  [38.488s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.489s]
Computing alignments...  [38.257s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.456s]
Computing alignments...  [38.314s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.408s]
Computing alignments...  [38.469s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.087s]
Sorting trace points...  [1.356s]
Computing alignments...  [38.473s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.287s]
Computing alignments...  [38.137s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [630.457s]
Deallocating reference...  [0.063s]
Loading reference sequences...  [26.818s]
Masking reference...  [25.213s]
Initializing dictionary...  [0.063s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [26.546s]
Allocating buffers...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.755s]
Building query seed array...  [2.447s]
Computing hash join...  [4.37s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [72.264s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [9.969s]
Building query seed array...  [2.798s]
Computing hash join...  [4.38s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [46.429s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [11.003s]
Building query seed array...  [2.987s]
Computing hash join...  [4.287s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [41.202s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [8.09s]
Building query seed array...  [2.374s]
Computing hash join...  [4.443s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [37.792s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [8.347s]
Building query seed array...  [2.218s]
Computing hash join...  [4.21s]
Masking low complexity seeds...  [0.2s]
Searching alignments...  [37.423s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [10.261s]
Building query seed array...  [2.576s]
Computing hash join...  [4.258s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [30.247s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [11.065s]
Building query seed array...  [2.669s]
Computing hash join...  [4.202s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [31.811s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [8.334s]
Building query seed array...  [2.25s]
Computing hash join...  [4.157s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [28.162s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.11s]
Clearing query masking...  [1.918s]
Opening temporary output file...  [0.012s]
Computing alignments... Loading trace points...  [6.3s]
Sorting trace points...  [1.054s]
Computing alignments...  [29.539s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.062s]
Sorting trace points...  [0.925s]
Computing alignments...  [29.328s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.173s]
Computing alignments...  [29.282s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.04s]
Sorting trace points...  [0.908s]
Computing alignments...  [29.193s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.132s]
Computing alignments...  [29.086s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.076s]
Computing alignments...  [29.473s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.119s]
Computing alignments...  [29.152s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.074s]
Sorting trace points...  [0.933s]
Computing alignments...  [29.097s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.588s]
Sorting trace points...  [1.007s]
Computing alignments...  [29.927s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.102s]
Sorting trace points...  [1.204s]
Computing alignments...  [30.647s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.138s]
Computing alignments...  [30.773s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.071s]
Sorting trace points...  [0.981s]
Computing alignments...  [30.643s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.064s]
Sorting trace points...  [0.988s]
Computing alignments...  [30.697s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.195s]
Computing alignments...  [30.744s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.188s]
Computing alignments...  [30.628s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.186s]
Computing alignments...  [30.463s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [503.895s]
Deallocating reference...  [0.05s]
Loading reference sequences...  [0.081s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [2228.12s]
 [2228.12s]
Deallocating queries...  [0.066s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [3.739s]
 [4.868s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 20255.8s
Reported 2863169762 pairwise alignments, 2863169762 HSPs.
15825951 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E10_R1.fastp-trim.20230215.fq.gz complete: E10_R1.blastx.meganized.daa

Now MEGANizing E10_R1.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: E10_R1.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 100% (264.3s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.3s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (5,299.9s)
Total reads:       15,825,951
With hits:          15,825,951 
Alignments:      2,859,006,419
Assig. Taxonomy:    14,983,543
Assig. SEED:           128,258
Assig. EGGNOG:          69,939
Assig. GTDB:           488,437
Assig. EC:           2,715,362
Assig. INTERPRO2GO:  1,441,607
MinSupport set to: 7912
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.4s)
Min-supp. changes:       4,117
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (13.2s)
Min-supp. changes:       3,280
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (54.9s)
Binning reads Syncing
100% (0.3s)
Class. Taxonomy:            61
Class. SEED:               511
Class. EGGNOG:           1,842
Class. GTDB:                19
Class. EC:               2,450
Class. INTERPRO2GO:      8,114
Total time:  5,643s
Peak memory: 29.5 of 195.3G
MEGANization of E10_R1.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E10_R2.fastp-trim.20230215.fq.gz...
7a996bdb3505afcbafa01de5508d9009  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E10_R2.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E10_R2.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.358s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.735s]
Opening the output file...  [0s]
Loading query sequences...  [89.519s]
Masking queries...  [22.736s]
Algorithm: Double-indexed
Building query histograms...  [22.147s]
Loading reference sequences...  [29.607s]
Masking reference...  [30.82s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.935s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.43s]
Building query seed array...  [2.678s]
Computing hash join...  [5.524s]
Masking low complexity seeds...  [0.267s]
Searching alignments...  [88.456s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [11.984s]
Building query seed array...  [2.837s]
Computing hash join...  [5.469s]
Masking low complexity seeds...  [0.273s]
Searching alignments...  [57.911s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [12.822s]
Building query seed array...  [3.032s]
Computing hash join...  [5.293s]
Masking low complexity seeds...  [0.27s]
Searching alignments...  [51.027s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.925s]
Building query seed array...  [2.503s]
Computing hash join...  [5.35s]
Masking low complexity seeds...  [0.266s]
Searching alignments...  [44.557s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.204s]
Building query seed array...  [2.185s]
Computing hash join...  [5.093s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [49.941s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.591s]
Building query seed array...  [2.578s]
Computing hash join...  [5.241s]
Masking low complexity seeds...  [0.266s]
Searching alignments...  [37.425s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.616s]
Building query seed array...  [2.622s]
Computing hash join...  [5.182s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [42.243s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.049s]
Building query seed array...  [2.286s]
Computing hash join...  [5.133s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [35.116s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.129s]
Clearing query masking...  [1.875s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.063s]
Sorting trace points...  [1.422s]
Computing alignments...  [36.103s]
Deallocating buffers...  [0.016s]
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Sorting trace points...  [1.396s]
Computing alignments...  [36.087s]
Deallocating buffers...  [0.019s]
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Sorting trace points...  [1.412s]
Computing alignments...  [36.511s]
Deallocating buffers...  [0.016s]
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Sorting trace points...  [1.383s]
Computing alignments...  [36.003s]
Deallocating buffers...  [0.026s]
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Sorting trace points...  [1.024s]
Computing alignments...  [36.178s]
Deallocating buffers...  [0.025s]
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Sorting trace points...  [1.377s]
Computing alignments...  [36.183s]
Deallocating buffers...  [0.026s]
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Computing alignments...  [36.495s]
Deallocating buffers...  [0.02s]
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Sorting trace points...  [1.25s]
Computing alignments...  [35.83s]
Deallocating buffers...  [0.02s]
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Sorting trace points...  [1.444s]
Computing alignments...  [37.748s]
Deallocating buffers...  [0.017s]
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Sorting trace points...  [1.357s]
Computing alignments...  [39.14s]
Deallocating buffers...  [0.021s]
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Sorting trace points...  [1.506s]
Computing alignments...  [39.362s]
Deallocating buffers...  [0.021s]
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Sorting trace points...  [1.498s]
Computing alignments...  [39.235s]
Deallocating buffers...  [0.017s]
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Sorting trace points...  [1.476s]
Computing alignments...  [39.023s]
Deallocating buffers...  [0.021s]
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Sorting trace points...  [1.47s]
Computing alignments...  [39.336s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.518s]
Computing alignments...  [39.645s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.488s]
Computing alignments...  [38.978s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
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Deallocating reference...  [0.06s]
Loading reference sequences...  [31.907s]
Masking reference...  [30.914s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.506s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.678s]
Building query seed array...  [2.545s]
Computing hash join...  [5.357s]
Masking low complexity seeds...  [0.272s]
Searching alignments...  [86.44s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.721s]
Building query seed array...  [2.913s]
Computing hash join...  [5.45s]
Masking low complexity seeds...  [0.285s]
Searching alignments...  [55.518s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.37s]
Building query seed array...  [3.004s]
Computing hash join...  [5.385s]
Masking low complexity seeds...  [0.266s]
Searching alignments...  [50.247s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.993s]
Building query seed array...  [2.455s]
Computing hash join...  [5.355s]
Masking low complexity seeds...  [0.27s]
Searching alignments...  [45.11s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.856s]
Building query seed array...  [2.211s]
Computing hash join...  [5.186s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [49.687s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.106s]
Building query seed array...  [2.56s]
Computing hash join...  [5.233s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [37.808s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.41s]
Building query seed array...  [2.773s]
Computing hash join...  [5.139s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [41.343s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.251s]
Building query seed array...  [2.245s]
Computing hash join...  [5.078s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [34.938s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.14s]
Clearing query masking...  [1.89s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.207s]
Sorting trace points...  [1.399s]
Computing alignments...  [36.175s]
Deallocating buffers...  [0.018s]
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Sorting trace points...  [1.354s]
Computing alignments...  [36.18s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.03s]
Computing alignments...  [36.559s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.377s]
Computing alignments...  [35.953s]
Deallocating buffers...  [0.022s]
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Sorting trace points...  [1.392s]
Computing alignments...  [36.365s]
Deallocating buffers...  [0.026s]
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Sorting trace points...  [1.369s]
Computing alignments...  [36.164s]
Deallocating buffers...  [0.016s]
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Sorting trace points...  [1.345s]
Computing alignments...  [36.574s]
Deallocating buffers...  [0.016s]
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Sorting trace points...  [1.138s]
Computing alignments...  [35.908s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.47s]
Computing alignments...  [37.767s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.296s]
Computing alignments...  [39.122s]
Deallocating buffers...  [0.02s]
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Sorting trace points...  [1.152s]
Computing alignments...  [39.279s]
Deallocating buffers...  [0.02s]
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Sorting trace points...  [1.537s]
Computing alignments...  [39.213s]
Deallocating buffers...  [0.029s]
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Sorting trace points...  [1.551s]
Computing alignments...  [38.845s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.467s]
Computing alignments...  [39.124s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.189s]
Computing alignments...  [39.426s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0s]
Sorting trace points...  [1.145s]
Computing alignments...  [38.978s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
 [631.982s]
Deallocating reference...  [0.068s]
Loading reference sequences...  [32.778s]
Masking reference...  [31.265s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.513s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.632s]
Building query seed array...  [2.538s]
Computing hash join...  [5.532s]
Masking low complexity seeds...  [0.269s]
Searching alignments...  [88.218s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.692s]
Building query seed array...  [2.905s]
Computing hash join...  [5.443s]
Masking low complexity seeds...  [0.268s]
Searching alignments...  [57.682s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.494s]
Building query seed array...  [3.039s]
Computing hash join...  [5.319s]
Masking low complexity seeds...  [0.27s]
Searching alignments...  [51.474s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.898s]
Building query seed array...  [2.467s]
Computing hash join...  [5.308s]
Masking low complexity seeds...  [0.259s]
Searching alignments...  [43.947s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.101s]
Building query seed array...  [2.178s]
Computing hash join...  [5.095s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [50.802s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.779s]
Building query seed array...  [2.599s]
Computing hash join...  [5.08s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [36.364s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.297s]
Building query seed array...  [2.782s]
Computing hash join...  [5.132s]
Masking low complexity seeds...  [0.265s]
Searching alignments...  [40.481s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.051s]
Building query seed array...  [2.276s]
Computing hash join...  [5.141s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [35.422s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.131s]
Clearing query masking...  [1.822s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.111s]
Sorting trace points...  [1.442s]
Computing alignments...  [35.878s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.411s]
Computing alignments...  [35.872s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.393s]
Computing alignments...  [36.427s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.381s]
Computing alignments...  [36.023s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.36s]
Computing alignments...  [36.013s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.372s]
Computing alignments...  [35.933s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.341s]
Computing alignments...  [36.442s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.306s]
Computing alignments...  [35.804s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.423s]
Computing alignments...  [37.77s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.351s]
Computing alignments...  [39.208s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.501s]
Computing alignments...  [39.464s]
Deallocating buffers...  [0.021s]
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Sorting trace points...  [1.515s]
Computing alignments...  [39.102s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.154s]
Computing alignments...  [38.905s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.536s]
Computing alignments...  [39.022s]
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Loading trace points...  [0.041s]
Sorting trace points...  [1.129s]
Computing alignments...  [39.357s]
Deallocating buffers...  [0.019s]
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Sorting trace points...  [1.474s]
Computing alignments...  [39.002s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [630.522s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [33.15s]
Masking reference...  [31.341s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.018s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.247s]
Building query seed array...  [2.427s]
Computing hash join...  [5.411s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [86.568s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.193s]
Building query seed array...  [2.815s]
Computing hash join...  [5.372s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [54.157s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.672s]
Building query seed array...  [2.98s]
Computing hash join...  [5.295s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [51.015s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.226s]
Building query seed array...  [2.453s]
Computing hash join...  [5.241s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [45.12s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.062s]
Building query seed array...  [2.26s]
Computing hash join...  [5.113s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [49.589s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.389s]
Building query seed array...  [2.645s]
Computing hash join...  [5.155s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [36.964s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.091s]
Building query seed array...  [2.719s]
Computing hash join...  [5.145s]
Masking low complexity seeds...  [0.272s]
Searching alignments...  [40.226s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.93s]
Building query seed array...  [2.278s]
Computing hash join...  [5.17s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [36.4s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.843s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [7.047s]
Sorting trace points...  [1.445s]
Computing alignments...  [35.904s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.218s]
Computing alignments...  [35.803s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.017s]
Computing alignments...  [36.225s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.002s]
Sorting trace points...  [1.376s]
Computing alignments...  [35.675s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.383s]
Computing alignments...  [35.997s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.21s]
Computing alignments...  [35.903s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.084s]
Computing alignments...  [36.249s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.287s]
Computing alignments...  [35.574s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.262s]
Computing alignments...  [37.617s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.458s]
Computing alignments...  [39.023s]
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Sorting trace points...  [1.404s]
Computing alignments...  [39.211s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.529s]
Computing alignments...  [38.951s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.241s]
Computing alignments...  [38.76s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.096s]
Sorting trace points...  [1.523s]
Computing alignments...  [38.884s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.481s]
Computing alignments...  [39.278s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.113s]
Computing alignments...  [38.815s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [627.173s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [245.563s]
Masking reference...  [30.943s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.852s]
Allocating buffers...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.707s]
Building query seed array...  [2.488s]
Computing hash join...  [5.388s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [87.706s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.588s]
Building query seed array...  [2.983s]
Computing hash join...  [5.344s]
Masking low complexity seeds...  [0.267s]
Searching alignments...  [55.057s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.377s]
Building query seed array...  [3.071s]
Computing hash join...  [5.366s]
Masking low complexity seeds...  [0.276s]
Searching alignments...  [50.6s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.163s]
Building query seed array...  [2.515s]
Computing hash join...  [5.294s]
Masking low complexity seeds...  [0.274s]
Searching alignments...  [44.808s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.37s]
Building query seed array...  [2.198s]
Computing hash join...  [5.113s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [49.033s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.559s]
Building query seed array...  [2.521s]
Computing hash join...  [5.072s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [37.481s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.077s]
Building query seed array...  [2.708s]
Computing hash join...  [5.145s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [42.121s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.221s]
Building query seed array...  [2.185s]
Computing hash join...  [5.052s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [35.866s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.781s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [7.095s]
Sorting trace points...  [1.402s]
Computing alignments...  [35.699s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.361s]
Computing alignments...  [35.801s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.431s]
Computing alignments...  [36.277s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.367s]
Computing alignments...  [35.557s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.04s]
Sorting trace points...  [1.366s]
Computing alignments...  [36.015s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.124s]
Sorting trace points...  [1.095s]
Computing alignments...  [35.962s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.388s]
Computing alignments...  [36.187s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.328s]
Computing alignments...  [35.553s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.329s]
Computing alignments...  [37.584s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.479s]
Computing alignments...  [38.938s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.325s]
Computing alignments...  [39.131s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.296s]
Computing alignments...  [38.907s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.186s]
Computing alignments...  [38.604s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.509s]
Computing alignments...  [38.881s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.136s]
Computing alignments...  [39.106s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.541s]
Computing alignments...  [38.687s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [626.783s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.734s]
Masking reference...  [30.845s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.874s]
Allocating buffers...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.386s]
Building query seed array...  [2.396s]
Computing hash join...  [5.401s]
Masking low complexity seeds...  [0.267s]
Searching alignments...  [86.611s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.015s]
Building query seed array...  [2.837s]
Computing hash join...  [5.357s]
Masking low complexity seeds...  [0.286s]
Searching alignments...  [55.651s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.438s]
Building query seed array...  [2.94s]
Computing hash join...  [5.354s]
Masking low complexity seeds...  [0.265s]
Searching alignments...  [49.933s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.926s]
Building query seed array...  [2.435s]
Computing hash join...  [5.376s]
Masking low complexity seeds...  [0.271s]
Searching alignments...  [44.658s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.888s]
Building query seed array...  [2.227s]
Computing hash join...  [5.147s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [47.222s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.471s]
Building query seed array...  [2.6s]
Computing hash join...  [5.103s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [36.646s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.446s]
Building query seed array...  [2.756s]
Computing hash join...  [5.043s]
Masking low complexity seeds...  [0.259s]
Searching alignments...  [39.095s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.421s]
Building query seed array...  [2.254s]
Computing hash join...  [5.123s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [35.106s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.128s]
Clearing query masking...  [1.876s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.995s]
Sorting trace points...  [1.376s]
Computing alignments...  [35.871s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.144s]
Computing alignments...  [35.742s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.272s]
Computing alignments...  [36.287s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.094s]
Sorting trace points...  [1.378s]
Computing alignments...  [35.575s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.409s]
Computing alignments...  [35.873s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.4s]
Computing alignments...  [35.78s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.436s]
Computing alignments...  [36.094s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.339s]
Computing alignments...  [35.461s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.472s]
Computing alignments...  [37.517s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.473s]
Computing alignments...  [38.757s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.466s]
Computing alignments...  [39.244s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.298s]
Computing alignments...  [39.165s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.482s]
Computing alignments...  [38.796s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.192s]
Sorting trace points...  [1.368s]
Computing alignments...  [38.813s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.515s]
Computing alignments...  [39.063s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [1.497s]
Computing alignments...  [38.63s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [627.384s]
Deallocating reference...  [0.063s]
Loading reference sequences...  [29.664s]
Masking reference...  [30.836s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.707s]
Allocating buffers...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.41s]
Building query seed array...  [2.478s]
Computing hash join...  [5.362s]
Masking low complexity seeds...  [0.267s]
Searching alignments...  [89.529s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.365s]
Building query seed array...  [2.904s]
Computing hash join...  [5.331s]
Masking low complexity seeds...  [0.256s]
Searching alignments...  [57.575s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.184s]
Building query seed array...  [2.999s]
Computing hash join...  [5.44s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [49.557s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.965s]
Building query seed array...  [2.38s]
Computing hash join...  [5.332s]
Masking low complexity seeds...  [0.268s]
Searching alignments...  [44.106s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.791s]
Building query seed array...  [2.175s]
Computing hash join...  [5.13s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [49.323s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.167s]
Building query seed array...  [2.597s]
Computing hash join...  [5.137s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [37.058s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.959s]
Building query seed array...  [2.717s]
Computing hash join...  [5.044s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [42.024s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.034s]
Building query seed array...  [2.243s]
Computing hash join...  [5.069s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [35.495s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.128s]
Clearing query masking...  [1.895s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.926s]
Sorting trace points...  [1.447s]
Computing alignments...  [36.182s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.025s]
Computing alignments...  [35.935s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.369s]
Computing alignments...  [36.383s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.04s]
Sorting trace points...  [1.361s]
Computing alignments...  [35.684s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.085s]
Computing alignments...  [36.098s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.416s]
Computing alignments...  [35.943s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.306s]
Computing alignments...  [36.322s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.371s]
Computing alignments...  [35.652s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.167s]
Computing alignments...  [37.68s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.467s]
Computing alignments...  [39.049s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.115s]
Sorting trace points...  [1.401s]
Computing alignments...  [39.312s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.586s]
Computing alignments...  [39.097s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.529s]
Computing alignments...  [38.883s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.495s]
Computing alignments...  [39.025s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.002s]
Sorting trace points...  [1.402s]
Computing alignments...  [39.313s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.097s]
Computing alignments...  [38.894s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0s]
 [628.929s]
Deallocating reference...  [0.073s]
Loading reference sequences...  [29.679s]
Masking reference...  [32.079s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.158s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.058s]
Building query seed array...  [2.4s]
Computing hash join...  [5.389s]
Masking low complexity seeds...  [0.267s]
Searching alignments...  [86.619s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.621s]
Building query seed array...  [2.841s]
Computing hash join...  [5.358s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [55.581s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.342s]
Building query seed array...  [2.994s]
Computing hash join...  [5.247s]
Masking low complexity seeds...  [0.267s]
Searching alignments...  [51.16s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.995s]
Building query seed array...  [2.387s]
Computing hash join...  [5.371s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [44.377s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.744s]
Building query seed array...  [2.238s]
Computing hash join...  [5.206s]
Masking low complexity seeds...  [0.265s]
Searching alignments...  [47.467s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.097s]
Building query seed array...  [2.481s]
Computing hash join...  [5.119s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [36.56s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.204s]
Building query seed array...  [2.707s]
Computing hash join...  [5.071s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [42.496s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.106s]
Building query seed array...  [2.241s]
Computing hash join...  [5.135s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [34.861s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.131s]
Clearing query masking...  [1.834s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.121s]
Sorting trace points...  [1.396s]
Computing alignments...  [35.946s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.359s]
Computing alignments...  [35.804s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.039s]
Sorting trace points...  [1.25s]
Computing alignments...  [36.371s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.337s]
Computing alignments...  [35.689s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.388s]
Computing alignments...  [36.024s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.429s]
Computing alignments...  [35.882s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.345s]
Computing alignments...  [36.306s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.154s]
Computing alignments...  [35.633s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.091s]
Sorting trace points...  [1.419s]
Computing alignments...  [37.609s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.17s]
Computing alignments...  [39.062s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.488s]
Computing alignments...  [39.443s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.559s]
Computing alignments...  [39.237s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.145s]
Computing alignments...  [38.877s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.503s]
Computing alignments...  [38.994s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.037s]
Sorting trace points...  [1.231s]
Computing alignments...  [39.392s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.117s]
Computing alignments...  [38.919s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [628.714s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.559s]
Masking reference...  [32.014s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.345s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.14s]
Building query seed array...  [2.537s]
Computing hash join...  [5.405s]
Masking low complexity seeds...  [0.266s]
Searching alignments...  [87.353s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.167s]
Building query seed array...  [2.952s]
Computing hash join...  [5.295s]
Masking low complexity seeds...  [0.27s]
Searching alignments...  [55.437s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.354s]
Building query seed array...  [2.936s]
Computing hash join...  [5.333s]
Masking low complexity seeds...  [0.272s]
Searching alignments...  [51.681s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.788s]
Building query seed array...  [2.419s]
Computing hash join...  [5.321s]
Masking low complexity seeds...  [0.268s]
Searching alignments...  [44.46s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.805s]
Building query seed array...  [2.301s]
Computing hash join...  [5.152s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [49.924s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.451s]
Building query seed array...  [2.578s]
Computing hash join...  [5.165s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [37.343s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.306s]
Building query seed array...  [2.718s]
Computing hash join...  [5.207s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [41.189s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.891s]
Building query seed array...  [2.208s]
Computing hash join...  [5.09s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [34.597s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.129s]
Clearing query masking...  [1.93s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.243s]
Sorting trace points...  [1.21s]
Computing alignments...  [36.032s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.117s]
Sorting trace points...  [1.398s]
Computing alignments...  [35.866s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.551s]
Sorting trace points...  [1.392s]
Computing alignments...  [36.228s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.096s]
Sorting trace points...  [1.348s]
Computing alignments...  [35.906s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.002s]
Sorting trace points...  [1.314s]
Computing alignments...  [36.035s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.357s]
Computing alignments...  [36.035s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.407s]
Computing alignments...  [36.376s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.322s]
Computing alignments...  [35.724s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.437s]
Computing alignments...  [37.693s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.512s]
Computing alignments...  [39.135s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.507s]
Computing alignments...  [39.221s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.459s]
Computing alignments...  [39.116s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.511s]
Computing alignments...  [38.83s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.506s]
Computing alignments...  [38.887s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.502s]
Computing alignments...  [39.281s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.477s]
Computing alignments...  [38.841s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [630.934s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.762s]
Masking reference...  [30.844s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.464s]
Allocating buffers...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.062s]
Building query seed array...  [2.538s]
Computing hash join...  [5.429s]
Masking low complexity seeds...  [0.271s]
Searching alignments...  [88.083s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.097s]
Building query seed array...  [2.849s]
Computing hash join...  [5.273s]
Masking low complexity seeds...  [0.275s]
Searching alignments...  [56.766s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.465s]
Building query seed array...  [3.048s]
Computing hash join...  [5.346s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [50.446s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.084s]
Building query seed array...  [2.529s]
Computing hash join...  [5.427s]
Masking low complexity seeds...  [0.275s]
Searching alignments...  [44.66s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.974s]
Building query seed array...  [2.313s]
Computing hash join...  [5.114s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [49.523s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.54s]
Building query seed array...  [2.654s]
Computing hash join...  [5.094s]
Masking low complexity seeds...  [0.267s]
Searching alignments...  [37.439s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.459s]
Building query seed array...  [2.728s]
Computing hash join...  [5.216s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [41.139s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.046s]
Building query seed array...  [2.225s]
Computing hash join...  [5.104s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [35.037s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.831s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.044s]
Sorting trace points...  [1.389s]
Computing alignments...  [35.865s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.393s]
Computing alignments...  [35.909s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.378s]
Computing alignments...  [36.388s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.33s]
Computing alignments...  [35.83s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.325s]
Computing alignments...  [36.121s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.389s]
Computing alignments...  [35.939s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.371s]
Computing alignments...  [36.356s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.33s]
Computing alignments...  [35.682s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.039s]
Sorting trace points...  [1.475s]
Computing alignments...  [37.599s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.246s]
Computing alignments...  [38.971s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.532s]
Computing alignments...  [39.249s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.539s]
Computing alignments...  [39.092s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.529s]
Computing alignments...  [38.819s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.581s]
Computing alignments...  [38.891s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.553s]
Computing alignments...  [39.384s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.533s]
Computing alignments...  [38.906s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [630.172s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.772s]
Masking reference...  [32.223s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.686s]
Allocating buffers...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.104s]
Building query seed array...  [2.461s]
Computing hash join...  [5.377s]
Masking low complexity seeds...  [0.267s]
Searching alignments...  [85.077s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.614s]
Building query seed array...  [2.904s]
Computing hash join...  [5.434s]
Masking low complexity seeds...  [0.273s]
Searching alignments...  [54.802s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.292s]
Building query seed array...  [2.87s]
Computing hash join...  [5.273s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [50.365s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.023s]
Building query seed array...  [2.453s]
Computing hash join...  [5.301s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [44.42s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.931s]
Building query seed array...  [2.284s]
Computing hash join...  [5.25s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [48.8s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.097s]
Building query seed array...  [2.59s]
Computing hash join...  [5.14s]
Masking low complexity seeds...  [0.259s]
Searching alignments...  [37.022s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.281s]
Building query seed array...  [2.749s]
Computing hash join...  [5.127s]
Masking low complexity seeds...  [0.259s]
Searching alignments...  [40.257s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.405s]
Building query seed array...  [2.214s]
Computing hash join...  [5.037s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [34.344s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.129s]
Clearing query masking...  [1.901s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.969s]
Sorting trace points...  [1.455s]
Computing alignments...  [35.675s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.38s]
Computing alignments...  [35.648s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.371s]
Computing alignments...  [36.055s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.355s]
Computing alignments...  [35.455s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.091s]
Sorting trace points...  [1.172s]
Computing alignments...  [35.842s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.333s]
Computing alignments...  [35.749s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.374s]
Computing alignments...  [36.059s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.315s]
Computing alignments...  [35.49s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.04s]
Sorting trace points...  [1.397s]
Computing alignments...  [37.423s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.547s]
Computing alignments...  [38.766s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.27s]
Computing alignments...  [39.058s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.107s]
Computing alignments...  [38.902s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.097s]
Sorting trace points...  [1.5s]
Computing alignments...  [38.686s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.361s]
Computing alignments...  [38.735s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.206s]
Computing alignments...  [39.07s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.11s]
Computing alignments...  [38.648s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [624.858s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.64s]
Masking reference...  [32.234s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [31.582s]
Allocating buffers...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.123s]
Building query seed array...  [2.476s]
Computing hash join...  [5.425s]
Masking low complexity seeds...  [0.265s]
Searching alignments...  [87.383s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.558s]
Building query seed array...  [2.802s]
Computing hash join...  [5.329s]
Masking low complexity seeds...  [0.268s]
Searching alignments...  [57.285s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.517s]
Building query seed array...  [2.997s]
Computing hash join...  [5.3s]
Masking low complexity seeds...  [0.266s]
Searching alignments...  [50.122s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.829s]
Building query seed array...  [2.468s]
Computing hash join...  [5.361s]
Masking low complexity seeds...  [0.27s]
Searching alignments...  [45.255s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.801s]
Building query seed array...  [2.192s]
Computing hash join...  [5.08s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [49.875s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.467s]
Building query seed array...  [2.644s]
Computing hash join...  [5.121s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [37.056s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.209s]
Building query seed array...  [2.768s]
Computing hash join...  [5.1s]
Masking low complexity seeds...  [0.268s]
Searching alignments...  [41.245s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.072s]
Building query seed array...  [2.249s]
Computing hash join...  [5.17s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [34.414s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.128s]
Clearing query masking...  [1.873s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [7.048s]
Sorting trace points...  [1.394s]
Computing alignments...  [36.418s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.077s]
Computing alignments...  [35.986s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.417s]
Computing alignments...  [36.439s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.002s]
Sorting trace points...  [1.304s]
Computing alignments...  [35.908s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.06s]
Computing alignments...  [36.206s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.14s]
Computing alignments...  [36.171s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.399s]
Computing alignments...  [36.538s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.298s]
Computing alignments...  [35.769s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.434s]
Computing alignments...  [37.801s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.091s]
Sorting trace points...  [1.299s]
Computing alignments...  [39.182s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.429s]
Computing alignments...  [39.336s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.176s]
Computing alignments...  [39.266s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.436s]
Computing alignments...  [38.975s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.524s]
Computing alignments...  [39.024s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.189s]
Computing alignments...  [39.401s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.501s]
Computing alignments...  [38.921s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [630.63s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [29.465s]
Masking reference...  [30.845s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.631s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.281s]
Building query seed array...  [2.483s]
Computing hash join...  [5.315s]
Masking low complexity seeds...  [0.265s]
Searching alignments...  [89.278s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.36s]
Building query seed array...  [2.858s]
Computing hash join...  [5.319s]
Masking low complexity seeds...  [0.274s]
Searching alignments...  [56.955s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.697s]
Building query seed array...  [3.044s]
Computing hash join...  [5.462s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [50.235s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.116s]
Building query seed array...  [2.477s]
Computing hash join...  [5.405s]
Masking low complexity seeds...  [0.268s]
Searching alignments...  [44.214s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.702s]
Building query seed array...  [2.268s]
Computing hash join...  [5.071s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [50.136s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.248s]
Building query seed array...  [2.608s]
Computing hash join...  [5.176s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [37.832s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.25s]
Building query seed array...  [2.738s]
Computing hash join...  [5.089s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [42.795s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.766s]
Building query seed array...  [2.232s]
Computing hash join...  [5.075s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [35.42s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.141s]
Clearing query masking...  [1.886s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.095s]
Sorting trace points...  [1.43s]
Computing alignments...  [35.705s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.291s]
Computing alignments...  [35.714s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.383s]
Computing alignments...  [36.133s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.274s]
Computing alignments...  [35.508s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.002s]
Sorting trace points...  [1.281s]
Computing alignments...  [35.981s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.159s]
Computing alignments...  [35.756s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.962s]
Sorting trace points...  [1.382s]
Computing alignments...  [36.116s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.321s]
Computing alignments...  [35.479s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.27s]
Computing alignments...  [37.44s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.396s]
Computing alignments...  [38.84s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.306s]
Computing alignments...  [39.1s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.486s]
Computing alignments...  [38.956s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.447s]
Computing alignments...  [38.696s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.337s]
Computing alignments...  [38.881s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.201s]
Computing alignments...  [39.14s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.475s]
Computing alignments...  [38.725s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [626.868s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [23.648s]
Masking reference...  [26.009s]
Initializing dictionary...  [0.064s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [26.149s]
Allocating buffers...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.555s]
Building query seed array...  [2.525s]
Computing hash join...  [4.568s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [70.496s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [10.077s]
Building query seed array...  [2.805s]
Computing hash join...  [4.523s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [45.457s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [11.089s]
Building query seed array...  [3.047s]
Computing hash join...  [4.484s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [41.961s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [8.192s]
Building query seed array...  [2.547s]
Computing hash join...  [4.488s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [35.745s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [8.044s]
Building query seed array...  [2.18s]
Computing hash join...  [4.232s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [40.076s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [10.096s]
Building query seed array...  [2.629s]
Computing hash join...  [4.241s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [30.111s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [11.037s]
Building query seed array...  [2.76s]
Computing hash join...  [4.439s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [33.174s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [7.88s]
Building query seed array...  [2.197s]
Computing hash join...  [4.255s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [28.651s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.121s]
Clearing query masking...  [1.888s]
Opening temporary output file...  [0.023s]
Computing alignments... Loading trace points...  [5.924s]
Sorting trace points...  [1.171s]
Computing alignments...  [28.7s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.112s]
Computing alignments...  [28.625s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.073s]
Sorting trace points...  [0.892s]
Computing alignments...  [28.868s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.051s]
Computing alignments...  [28.516s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.022s]
Computing alignments...  [28.734s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.12s]
Computing alignments...  [28.636s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.07s]
Sorting trace points...  [0.976s]
Computing alignments...  [28.902s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.067s]
Computing alignments...  [28.387s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.107s]
Sorting trace points...  [0.872s]
Computing alignments...  [29.977s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.049s]
Computing alignments...  [31.041s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.04s]
Sorting trace points...  [1.26s]
Computing alignments...  [31.333s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.088s]
Sorting trace points...  [0.959s]
Computing alignments...  [31.145s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.08s]
Computing alignments...  [31.015s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.178s]
Computing alignments...  [31.046s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.212s]
Computing alignments...  [31.299s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.199s]
Computing alignments...  [30.905s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
 [501.499s]
Deallocating reference...  [0.048s]
Loading reference sequences...  [0.103s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [2199.34s]
 [2199.34s]
Deallocating queries...  [0.072s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [3.735s]
 [4.806s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 20282.3s
Reported 2773040126 pairwise alignments, 2773040126 HSPs.
16257196 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E10_R2.fastp-trim.20230215.fq.gz complete: E10_R2.blastx.meganized.daa

Now MEGANizing E10_R2.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: E10_R2.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 100% (242.6s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.2s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (5,068.1s)
Total reads:       16,257,196
With hits:          16,257,196 
Alignments:      2,770,177,896
Assig. Taxonomy:    15,333,871
Assig. SEED:           123,697
Assig. EGGNOG:          68,949
Assig. GTDB:           471,827
Assig. EC:           2,770,308
Assig. INTERPRO2GO:  1,431,027
MinSupport set to: 8128
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.4s)
Min-supp. changes:       4,206
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (12.6s)
Min-supp. changes:       3,415
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (51.0s)
Binning reads Syncing
100% (0.4s)
Class. Taxonomy:            68
Class. SEED:               511
Class. EGGNOG:           1,831
Class. GTDB:                18
Class. EC:               2,428
Class. INTERPRO2GO:      8,162
Total time:  5,384s
Peak memory: 33.7 of 195.3G
MEGANization of E10_R2.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E11_R1.fastp-trim.20230215.fq.gz...
2dc1924597d0685cf33a8f4dde5a921c  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E11_R1.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E11_R1.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.329s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.743s]
Opening the output file...  [0s]
Loading query sequences...  [57.743s]
Masking queries...  [14.543s]
Algorithm: Double-indexed
Building query histograms...  [13.346s]
Loading reference sequences...  [31.519s]
Masking reference...  [32.112s]
Initializing dictionary...  [0.195s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.788s]
Allocating buffers...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.433s]
Building query seed array...  [1.608s]
Computing hash join...  [5.038s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [58.072s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.278s]
Building query seed array...  [1.889s]
Computing hash join...  [4.961s]
Masking low complexity seeds...  [0.196s]
Searching alignments...  [36.048s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.261s]
Building query seed array...  [1.975s]
Computing hash join...  [4.933s]
Masking low complexity seeds...  [0.191s]
Searching alignments...  [31.552s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.19s]
Building query seed array...  [1.624s]
Computing hash join...  [4.932s]
Masking low complexity seeds...  [0.196s]
Searching alignments...  [28.898s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.057s]
Building query seed array...  [1.47s]
Computing hash join...  [4.712s]
Masking low complexity seeds...  [0.177s]
Searching alignments...  [29.43s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.617s]
Building query seed array...  [1.716s]
Computing hash join...  [4.775s]
Masking low complexity seeds...  [0.192s]
Searching alignments...  [22.306s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.962s]
Building query seed array...  [1.76s]
Computing hash join...  [4.772s]
Masking low complexity seeds...  [0.182s]
Searching alignments...  [25.087s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.206s]
Building query seed array...  [1.501s]
Computing hash join...  [4.797s]
Masking low complexity seeds...  [0.19s]
Searching alignments...  [23.169s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.119s]
Clearing query masking...  [1.251s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [9.165s]
Sorting trace points...  [1.76s]
Computing alignments...  [43.892s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.137s]
Sorting trace points...  [1.613s]
Computing alignments...  [43.479s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.135s]
Sorting trace points...  [1.509s]
Computing alignments...  [43.908s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.109s]
Sorting trace points...  [1.379s]
Computing alignments...  [43.532s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.2s]
Sorting trace points...  [1.512s]
Computing alignments...  [45.21s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.16s]
Sorting trace points...  [1.562s]
Computing alignments...  [45.797s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.133s]
Sorting trace points...  [1.758s]
Computing alignments...  [45.719s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
Sorting trace points...  [1.732s]
Computing alignments...  [45.5s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [380.181s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [29.598s]
Masking reference...  [30.912s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [33.142s]
Allocating buffers...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.249s]
Building query seed array...  [1.582s]
Computing hash join...  [4.907s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [56.24s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.261s]
Building query seed array...  [1.835s]
Computing hash join...  [4.894s]
Masking low complexity seeds...  [0.185s]
Searching alignments...  [35.965s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.387s]
Building query seed array...  [1.976s]
Computing hash join...  [4.935s]
Masking low complexity seeds...  [0.189s]
Searching alignments...  [32.21s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.187s]
Building query seed array...  [1.531s]
Computing hash join...  [4.853s]
Masking low complexity seeds...  [0.192s]
Searching alignments...  [27.159s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.071s]
Building query seed array...  [1.474s]
Computing hash join...  [4.78s]
Masking low complexity seeds...  [0.185s]
Searching alignments...  [28.075s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.172s]
Building query seed array...  [1.669s]
Computing hash join...  [4.747s]
Masking low complexity seeds...  [0.183s]
Searching alignments...  [22.786s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.954s]
Building query seed array...  [1.79s]
Computing hash join...  [4.772s]
Masking low complexity seeds...  [0.189s]
Searching alignments...  [25.053s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.281s]
Building query seed array...  [1.469s]
Computing hash join...  [4.746s]
Masking low complexity seeds...  [0.182s]
Searching alignments...  [21.653s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.254s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [9.166s]
Sorting trace points...  [1.759s]
Computing alignments...  [43.776s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.143s]
Sorting trace points...  [1.506s]
Computing alignments...  [43.448s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.164s]
Sorting trace points...  [1.502s]
Computing alignments...  [43.772s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.11s]
Sorting trace points...  [1.295s]
Computing alignments...  [43.344s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.157s]
Sorting trace points...  [1.768s]
Computing alignments...  [45.03s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.124s]
Sorting trace points...  [1.766s]
Computing alignments...  [45.745s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.17s]
Sorting trace points...  [1.348s]
Computing alignments...  [45.618s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [1.727s]
Computing alignments...  [45.43s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
 [379.145s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [29.385s]
Masking reference...  [30.97s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.644s]
Allocating buffers...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.251s]
Building query seed array...  [1.612s]
Computing hash join...  [4.906s]
Masking low complexity seeds...  [0.186s]
Searching alignments...  [57.275s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.536s]
Building query seed array...  [1.91s]
Computing hash join...  [4.849s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [34.529s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.416s]
Building query seed array...  [1.986s]
Computing hash join...  [4.906s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [31.247s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.163s]
Building query seed array...  [1.648s]
Computing hash join...  [4.84s]
Masking low complexity seeds...  [0.187s]
Searching alignments...  [28.066s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.007s]
Building query seed array...  [1.436s]
Computing hash join...  [4.701s]
Masking low complexity seeds...  [0.184s]
Searching alignments...  [29.843s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.074s]
Building query seed array...  [1.649s]
Computing hash join...  [4.676s]
Masking low complexity seeds...  [0.184s]
Searching alignments...  [22.412s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.429s]
Building query seed array...  [1.782s]
Computing hash join...  [4.824s]
Masking low complexity seeds...  [0.193s]
Searching alignments...  [25.221s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.033s]
Building query seed array...  [1.431s]
Computing hash join...  [4.74s]
Masking low complexity seeds...  [0.183s]
Searching alignments...  [23.473s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.119s]
Clearing query masking...  [1.237s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [9.166s]
Sorting trace points...  [1.781s]
Computing alignments...  [43.756s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.126s]
Sorting trace points...  [1.656s]
Computing alignments...  [43.323s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.141s]
Sorting trace points...  [1.666s]
Computing alignments...  [43.695s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.149s]
Sorting trace points...  [1.603s]
Computing alignments...  [43.358s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.248s]
Sorting trace points...  [1.403s]
Computing alignments...  [45.167s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.123s]
Sorting trace points...  [1.618s]
Computing alignments...  [45.829s]
Deallocating buffers...  [0.024s]
Loading trace points...  [1.3s]
Sorting trace points...  [1.445s]
Computing alignments...  [45.53s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.532s]
Computing alignments...  [45.489s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [380.367s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [33.487s]
Masking reference...  [31.315s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.903s]
Allocating buffers...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.035s]
Building query seed array...  [1.61s]
Computing hash join...  [4.855s]
Masking low complexity seeds...  [0.189s]
Searching alignments...  [57.607s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.539s]
Building query seed array...  [1.826s]
Computing hash join...  [4.886s]
Masking low complexity seeds...  [0.189s]
Searching alignments...  [36.697s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.63s]
Building query seed array...  [2.016s]
Computing hash join...  [4.89s]
Masking low complexity seeds...  [0.193s]
Searching alignments...  [31.883s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.422s]
Building query seed array...  [1.632s]
Computing hash join...  [4.937s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [27.598s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.097s]
Building query seed array...  [1.473s]
Computing hash join...  [4.72s]
Masking low complexity seeds...  [0.188s]
Searching alignments...  [28.146s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.572s]
Building query seed array...  [1.652s]
Computing hash join...  [4.804s]
Masking low complexity seeds...  [0.183s]
Searching alignments...  [22.614s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.476s]
Building query seed array...  [1.855s]
Computing hash join...  [4.715s]
Masking low complexity seeds...  [0.179s]
Searching alignments...  [25.226s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.303s]
Building query seed array...  [1.42s]
Computing hash join...  [4.724s]
Masking low complexity seeds...  [0.175s]
Searching alignments...  [21.645s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.263s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [9.112s]
Sorting trace points...  [1.724s]
Computing alignments...  [43.67s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.2s]
Sorting trace points...  [1.235s]
Computing alignments...  [43.344s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.15s]
Sorting trace points...  [1.688s]
Computing alignments...  [43.75s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.111s]
Sorting trace points...  [1.599s]
Computing alignments...  [43.54s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.178s]
Sorting trace points...  [1.66s]
Computing alignments...  [45.166s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.138s]
Sorting trace points...  [1.793s]
Computing alignments...  [45.78s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.144s]
Sorting trace points...  [1.333s]
Computing alignments...  [45.533s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [1.394s]
Computing alignments...  [45.45s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [378.951s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [29.552s]
Masking reference...  [30.913s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.682s]
Allocating buffers...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.449s]
Building query seed array...  [1.616s]
Computing hash join...  [4.921s]
Masking low complexity seeds...  [0.189s]
Searching alignments...  [53.93s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.274s]
Building query seed array...  [1.874s]
Computing hash join...  [4.909s]
Masking low complexity seeds...  [0.2s]
Searching alignments...  [34.373s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.661s]
Building query seed array...  [2.012s]
Computing hash join...  [4.903s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [31.047s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.185s]
Building query seed array...  [1.701s]
Computing hash join...  [4.844s]
Masking low complexity seeds...  [0.198s]
Searching alignments...  [28.347s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.964s]
Building query seed array...  [1.429s]
Computing hash join...  [4.72s]
Masking low complexity seeds...  [0.177s]
Searching alignments...  [28.531s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.29s]
Building query seed array...  [1.705s]
Computing hash join...  [4.745s]
Masking low complexity seeds...  [0.186s]
Searching alignments...  [22.26s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.498s]
Building query seed array...  [1.773s]
Computing hash join...  [4.739s]
Masking low complexity seeds...  [0.179s]
Searching alignments...  [24.485s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.127s]
Building query seed array...  [1.444s]
Computing hash join...  [4.707s]
Masking low complexity seeds...  [0.197s]
Searching alignments...  [22.036s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.128s]
Clearing query masking...  [1.232s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [9.251s]
Sorting trace points...  [1.765s]
Computing alignments...  [43.508s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.167s]
Sorting trace points...  [1.633s]
Computing alignments...  [43.251s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.176s]
Sorting trace points...  [1.52s]
Computing alignments...  [43.668s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.123s]
Sorting trace points...  [1.636s]
Computing alignments...  [43.458s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.162s]
Sorting trace points...  [1.723s]
Computing alignments...  [45.038s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.144s]
Sorting trace points...  [1.743s]
Computing alignments...  [45.593s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.158s]
Sorting trace points...  [1.469s]
Computing alignments...  [45.466s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
Sorting trace points...  [1.431s]
Computing alignments...  [45.249s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [378.586s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [31.812s]
Masking reference...  [31.144s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.171s]
Allocating buffers...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.149s]
Building query seed array...  [1.628s]
Computing hash join...  [4.96s]
Masking low complexity seeds...  [0.196s]
Searching alignments...  [54.641s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.841s]
Building query seed array...  [1.866s]
Computing hash join...  [4.853s]
Masking low complexity seeds...  [0.196s]
Searching alignments...  [35.579s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.003s]
Building query seed array...  [1.969s]
Computing hash join...  [4.897s]
Masking low complexity seeds...  [0.19s]
Searching alignments...  [32.343s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.175s]
Building query seed array...  [1.615s]
Computing hash join...  [4.853s]
Masking low complexity seeds...  [0.2s]
Searching alignments...  [26.983s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.647s]
Building query seed array...  [1.471s]
Computing hash join...  [4.706s]
Masking low complexity seeds...  [0.185s]
Searching alignments...  [27.964s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.221s]
Building query seed array...  [1.682s]
Computing hash join...  [4.706s]
Masking low complexity seeds...  [0.182s]
Searching alignments...  [22.485s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.541s]
Building query seed array...  [1.836s]
Computing hash join...  [4.731s]
Masking low complexity seeds...  [0.182s]
Searching alignments...  [25.098s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.869s]
Building query seed array...  [1.524s]
Computing hash join...  [4.731s]
Masking low complexity seeds...  [0.181s]
Searching alignments...  [20.809s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.118s]
Clearing query masking...  [1.246s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [9.228s]
Sorting trace points...  [1.669s]
Computing alignments...  [43.522s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.157s]
Sorting trace points...  [1.599s]
Computing alignments...  [43.07s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.143s]
Sorting trace points...  [1.299s]
Computing alignments...  [43.486s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.16s]
Sorting trace points...  [1.378s]
Computing alignments...  [43.233s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.149s]
Sorting trace points...  [1.68s]
Computing alignments...  [44.864s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.119s]
Sorting trace points...  [1.609s]
Computing alignments...  [45.382s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.122s]
Sorting trace points...  [1.736s]
Computing alignments...  [45.379s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.259s]
Computing alignments...  [45.176s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [376.63s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [29.497s]
Masking reference...  [30.889s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.372s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.593s]
Building query seed array...  [1.603s]
Computing hash join...  [4.905s]
Masking low complexity seeds...  [0.189s]
Searching alignments...  [57.118s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.615s]
Building query seed array...  [1.917s]
Computing hash join...  [4.981s]
Masking low complexity seeds...  [0.194s]
Searching alignments...  [34.434s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [14.062s]
Building query seed array...  [1.978s]
Computing hash join...  [4.936s]
Masking low complexity seeds...  [0.194s]
Searching alignments...  [31.347s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.245s]
Building query seed array...  [1.596s]
Computing hash join...  [4.929s]
Masking low complexity seeds...  [0.198s]
Searching alignments...  [27.686s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.105s]
Building query seed array...  [1.519s]
Computing hash join...  [4.734s]
Masking low complexity seeds...  [0.193s]
Searching alignments...  [28.457s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.969s]
Building query seed array...  [1.668s]
Computing hash join...  [4.801s]
Masking low complexity seeds...  [0.185s]
Searching alignments...  [22.453s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.045s]
Building query seed array...  [1.776s]
Computing hash join...  [4.713s]
Masking low complexity seeds...  [0.178s]
Searching alignments...  [24.833s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.123s]
Building query seed array...  [1.418s]
Computing hash join...  [4.65s]
Masking low complexity seeds...  [0.176s]
Searching alignments...  [22.348s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.122s]
Clearing query masking...  [1.333s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [9.283s]
Sorting trace points...  [1.724s]
Computing alignments...  [43.565s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.105s]
Sorting trace points...  [1.641s]
Computing alignments...  [43.481s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.158s]
Sorting trace points...  [1.618s]
Computing alignments...  [43.826s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.138s]
Sorting trace points...  [1.512s]
Computing alignments...  [43.541s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.18s]
Sorting trace points...  [1.545s]
Computing alignments...  [45.147s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.144s]
Sorting trace points...  [1.729s]
Computing alignments...  [45.698s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.149s]
Sorting trace points...  [1.754s]
Computing alignments...  [45.507s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
Sorting trace points...  [1.748s]
Computing alignments...  [45.313s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
 [379.78s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [31.64s]
Masking reference...  [30.83s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.517s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.004s]
Building query seed array...  [1.593s]
Computing hash join...  [4.896s]
Masking low complexity seeds...  [0.193s]
Searching alignments...  [58.255s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.912s]
Building query seed array...  [1.841s]
Computing hash join...  [4.88s]
Masking low complexity seeds...  [0.196s]
Searching alignments...  [37.069s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.623s]
Building query seed array...  [1.947s]
Computing hash join...  [4.919s]
Masking low complexity seeds...  [0.198s]
Searching alignments...  [32.609s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.843s]
Building query seed array...  [1.601s]
Computing hash join...  [4.832s]
Masking low complexity seeds...  [0.191s]
Searching alignments...  [27.678s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.241s]
Building query seed array...  [1.444s]
Computing hash join...  [4.758s]
Masking low complexity seeds...  [0.188s]
Searching alignments...  [28.259s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.515s]
Building query seed array...  [1.684s]
Computing hash join...  [4.688s]
Masking low complexity seeds...  [0.179s]
Searching alignments...  [22.97s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.517s]
Building query seed array...  [1.797s]
Computing hash join...  [4.778s]
Masking low complexity seeds...  [0.182s]
Searching alignments...  [25.82s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.842s]
Building query seed array...  [1.405s]
Computing hash join...  [4.701s]
Masking low complexity seeds...  [0.189s]
Searching alignments...  [21.437s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.12s]
Clearing query masking...  [1.197s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [9.152s]
Sorting trace points...  [1.752s]
Computing alignments...  [43.482s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.148s]
Sorting trace points...  [1.635s]
Computing alignments...  [43.155s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.162s]
Sorting trace points...  [1.627s]
Computing alignments...  [43.608s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.138s]
Sorting trace points...  [1.592s]
Computing alignments...  [43.264s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.711s]
Computing alignments...  [44.97s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.148s]
Sorting trace points...  [1.715s]
Computing alignments...  [45.539s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.173s]
Sorting trace points...  [1.68s]
Computing alignments...  [45.506s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.352s]
Computing alignments...  [45.26s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [378.173s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [29.497s]
Masking reference...  [30.819s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.841s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.177s]
Building query seed array...  [1.592s]
Computing hash join...  [5s]
Masking low complexity seeds...  [0.195s]
Searching alignments...  [57.426s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.166s]
Building query seed array...  [1.856s]
Computing hash join...  [4.819s]
Masking low complexity seeds...  [0.189s]
Searching alignments...  [34.638s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.321s]
Building query seed array...  [1.999s]
Computing hash join...  [4.851s]
Masking low complexity seeds...  [0.196s]
Searching alignments...  [30.704s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.977s]
Building query seed array...  [1.601s]
Computing hash join...  [4.799s]
Masking low complexity seeds...  [0.188s]
Searching alignments...  [27.818s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.133s]
Building query seed array...  [1.469s]
Computing hash join...  [4.692s]
Masking low complexity seeds...  [0.182s]
Searching alignments...  [29.957s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.225s]
Building query seed array...  [1.697s]
Computing hash join...  [4.718s]
Masking low complexity seeds...  [0.181s]
Searching alignments...  [22.741s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.1s]
Building query seed array...  [1.87s]
Computing hash join...  [4.77s]
Masking low complexity seeds...  [0.186s]
Searching alignments...  [24.948s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.042s]
Building query seed array...  [1.424s]
Computing hash join...  [4.619s]
Masking low complexity seeds...  [0.176s]
Searching alignments...  [22.219s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.122s]
Clearing query masking...  [1.184s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [9.314s]
Sorting trace points...  [1.709s]
Computing alignments...  [43.516s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.103s]
Sorting trace points...  [1.647s]
Computing alignments...  [43.149s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.157s]
Sorting trace points...  [1.61s]
Computing alignments...  [43.536s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.122s]
Sorting trace points...  [1.672s]
Computing alignments...  [43.215s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.166s]
Sorting trace points...  [1.428s]
Computing alignments...  [44.883s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.124s]
Sorting trace points...  [1.623s]
Computing alignments...  [45.496s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.142s]
Sorting trace points...  [1.676s]
Computing alignments...  [45.456s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
Sorting trace points...  [1.701s]
Computing alignments...  [45.327s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
 [378.043s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [31.607s]
Masking reference...  [32.072s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [31.804s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.24s]
Building query seed array...  [1.613s]
Computing hash join...  [4.888s]
Masking low complexity seeds...  [0.198s]
Searching alignments...  [57.741s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.988s]
Building query seed array...  [1.916s]
Computing hash join...  [4.901s]
Masking low complexity seeds...  [0.191s]
Searching alignments...  [35.618s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.089s]
Building query seed array...  [1.988s]
Computing hash join...  [4.854s]
Masking low complexity seeds...  [0.191s]
Searching alignments...  [32.984s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.31s]
Building query seed array...  [1.648s]
Computing hash join...  [4.813s]
Masking low complexity seeds...  [0.197s]
Searching alignments...  [27.257s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.115s]
Building query seed array...  [1.479s]
Computing hash join...  [4.729s]
Masking low complexity seeds...  [0.18s]
Searching alignments...  [28.422s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.885s]
Building query seed array...  [1.673s]
Computing hash join...  [4.758s]
Masking low complexity seeds...  [0.185s]
Searching alignments...  [22.616s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.466s]
Building query seed array...  [1.803s]
Computing hash join...  [4.706s]
Masking low complexity seeds...  [0.184s]
Searching alignments...  [26.031s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.193s]
Building query seed array...  [1.456s]
Computing hash join...  [4.72s]
Masking low complexity seeds...  [0.184s]
Searching alignments...  [21.816s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.118s]
Clearing query masking...  [1.252s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [9.215s]
Sorting trace points...  [1.791s]
Computing alignments...  [43.581s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.134s]
Sorting trace points...  [1.32s]
Computing alignments...  [43.229s]
Deallocating buffers...  [0.212s]
Loading trace points...  [0.144s]
Sorting trace points...  [1.398s]
Computing alignments...  [43.775s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.138s]
Sorting trace points...  [1.533s]
Computing alignments...  [43.24s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.14s]
Sorting trace points...  [1.761s]
Computing alignments...  [44.908s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.148s]
Sorting trace points...  [1.817s]
Computing alignments...  [45.542s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.168s]
Sorting trace points...  [1.744s]
Computing alignments...  [45.545s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.716s]
Computing alignments...  [45.415s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
 [378.872s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.639s]
Masking reference...  [30.828s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.006s]
Building reference histograms...  [32.797s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.269s]
Building query seed array...  [1.656s]
Computing hash join...  [4.938s]
Masking low complexity seeds...  [0.197s]
Searching alignments...  [54.578s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.517s]
Building query seed array...  [1.895s]
Computing hash join...  [4.829s]
Masking low complexity seeds...  [0.19s]
Searching alignments...  [34.06s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.245s]
Building query seed array...  [2.024s]
Computing hash join...  [4.751s]
Masking low complexity seeds...  [0.191s]
Searching alignments...  [30.387s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.134s]
Building query seed array...  [1.601s]
Computing hash join...  [4.853s]
Masking low complexity seeds...  [0.196s]
Searching alignments...  [27.728s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.952s]
Building query seed array...  [1.45s]
Computing hash join...  [4.661s]
Masking low complexity seeds...  [0.182s]
Searching alignments...  [29.388s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.191s]
Building query seed array...  [1.688s]
Computing hash join...  [4.717s]
Masking low complexity seeds...  [0.189s]
Searching alignments...  [22.208s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.63s]
Building query seed array...  [1.8s]
Computing hash join...  [4.726s]
Masking low complexity seeds...  [0.175s]
Searching alignments...  [25.013s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.07s]
Building query seed array...  [1.498s]
Computing hash join...  [4.61s]
Masking low complexity seeds...  [0.187s]
Searching alignments...  [22.553s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.121s]
Clearing query masking...  [1.263s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [9.146s]
Sorting trace points...  [1.703s]
Computing alignments...  [43.569s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.122s]
Sorting trace points...  [1.651s]
Computing alignments...  [43.203s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.139s]
Sorting trace points...  [1.677s]
Computing alignments...  [43.473s]
Deallocating buffers...  [0.032s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.647s]
Computing alignments...  [43.082s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.135s]
Sorting trace points...  [1.707s]
Computing alignments...  [44.781s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.121s]
Sorting trace points...  [1.726s]
Computing alignments...  [45.431s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.131s]
Sorting trace points...  [1.566s]
Computing alignments...  [45.295s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.328s]
Computing alignments...  [45.286s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [377.266s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.562s]
Masking reference...  [32.097s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.121s]
Allocating buffers...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.396s]
Building query seed array...  [1.626s]
Computing hash join...  [4.928s]
Masking low complexity seeds...  [0.198s]
Searching alignments...  [58.891s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.645s]
Building query seed array...  [1.835s]
Computing hash join...  [4.854s]
Masking low complexity seeds...  [0.19s]
Searching alignments...  [38.063s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.198s]
Building query seed array...  [1.948s]
Computing hash join...  [4.871s]
Masking low complexity seeds...  [0.196s]
Searching alignments...  [32.245s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.961s]
Building query seed array...  [1.587s]
Computing hash join...  [4.823s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [27.566s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.932s]
Building query seed array...  [1.399s]
Computing hash join...  [4.669s]
Masking low complexity seeds...  [0.192s]
Searching alignments...  [28.519s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.115s]
Building query seed array...  [1.745s]
Computing hash join...  [4.719s]
Masking low complexity seeds...  [0.186s]
Searching alignments...  [22.558s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.405s]
Building query seed array...  [1.803s]
Computing hash join...  [4.737s]
Masking low complexity seeds...  [0.185s]
Searching alignments...  [24.731s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.554s]
Building query seed array...  [1.472s]
Computing hash join...  [4.775s]
Masking low complexity seeds...  [0.182s]
Searching alignments...  [21.59s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.12s]
Clearing query masking...  [1.266s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [9.053s]
Sorting trace points...  [1.768s]
Computing alignments...  [43.583s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.108s]
Sorting trace points...  [1.696s]
Computing alignments...  [43.309s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.141s]
Sorting trace points...  [1.692s]
Computing alignments...  [43.672s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.137s]
Sorting trace points...  [1.697s]
Computing alignments...  [43.314s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.192s]
Sorting trace points...  [1.498s]
Computing alignments...  [45.011s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.17s]
Sorting trace points...  [1.428s]
Computing alignments...  [45.706s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.137s]
Sorting trace points...  [1.398s]
Computing alignments...  [45.563s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [1.705s]
Computing alignments...  [45.456s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [378.707s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.73s]
Masking reference...  [32.105s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.175s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.135s]
Building query seed array...  [1.686s]
Computing hash join...  [4.919s]
Masking low complexity seeds...  [0.195s]
Searching alignments...  [56.103s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.415s]
Building query seed array...  [1.859s]
Computing hash join...  [4.978s]
Masking low complexity seeds...  [0.195s]
Searching alignments...  [34.61s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.106s]
Building query seed array...  [1.975s]
Computing hash join...  [4.884s]
Masking low complexity seeds...  [0.194s]
Searching alignments...  [30.962s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.724s]
Building query seed array...  [1.595s]
Computing hash join...  [4.859s]
Masking low complexity seeds...  [0.194s]
Searching alignments...  [27.942s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.858s]
Building query seed array...  [1.465s]
Computing hash join...  [4.749s]
Masking low complexity seeds...  [0.183s]
Searching alignments...  [27.939s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.358s]
Building query seed array...  [1.706s]
Computing hash join...  [4.63s]
Masking low complexity seeds...  [0.187s]
Searching alignments...  [22.316s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.632s]
Building query seed array...  [1.831s]
Computing hash join...  [4.751s]
Masking low complexity seeds...  [0.185s]
Searching alignments...  [25.33s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.147s]
Building query seed array...  [1.507s]
Computing hash join...  [4.628s]
Masking low complexity seeds...  [0.178s]
Searching alignments...  [21.586s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.121s]
Clearing query masking...  [1.251s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [9.264s]
Sorting trace points...  [1.716s]
Computing alignments...  [43.459s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.116s]
Sorting trace points...  [1.214s]
Computing alignments...  [43.268s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.149s]
Sorting trace points...  [1.643s]
Computing alignments...  [43.642s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.126s]
Sorting trace points...  [1.674s]
Computing alignments...  [43.214s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.14s]
Sorting trace points...  [1.656s]
Computing alignments...  [44.872s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.149s]
Sorting trace points...  [1.683s]
Computing alignments...  [45.648s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.15s]
Sorting trace points...  [1.81s]
Computing alignments...  [45.431s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.726s]
Computing alignments...  [45.403s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [378.426s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [26.327s]
Masking reference...  [25.853s]
Initializing dictionary...  [0.063s]
Initializing temporary storage...  [0.006s]
Building reference histograms...  [26.188s]
Allocating buffers...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.538s]
Building query seed array...  [1.599s]
Computing hash join...  [4.028s]
Masking low complexity seeds...  [0.184s]
Searching alignments...  [43.686s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [9.773s]
Building query seed array...  [1.903s]
Computing hash join...  [3.994s]
Masking low complexity seeds...  [0.18s]
Searching alignments...  [28.892s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [10.849s]
Building query seed array...  [2.015s]
Computing hash join...  [4.036s]
Masking low complexity seeds...  [0.184s]
Searching alignments...  [26.686s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [8.34s]
Building query seed array...  [1.601s]
Computing hash join...  [4.087s]
Masking low complexity seeds...  [0.187s]
Searching alignments...  [22.164s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [8.194s]
Building query seed array...  [1.463s]
Computing hash join...  [3.929s]
Masking low complexity seeds...  [0.184s]
Searching alignments...  [23.121s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [10.252s]
Building query seed array...  [1.733s]
Computing hash join...  [3.921s]
Masking low complexity seeds...  [0.178s]
Searching alignments...  [20.611s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [10.653s]
Building query seed array...  [1.765s]
Computing hash join...  [3.92s]
Masking low complexity seeds...  [0.178s]
Searching alignments...  [20.218s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [8.052s]
Building query seed array...  [1.468s]
Computing hash join...  [3.892s]
Masking low complexity seeds...  [0.172s]
Searching alignments...  [17.951s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.105s]
Clearing query masking...  [1.19s]
Opening temporary output file...  [0.018s]
Computing alignments... Loading trace points...  [11.819s]
Sorting trace points...  [2.056s]
Computing alignments...  [51.993s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.2s]
Sorting trace points...  [1.665s]
Computing alignments...  [52.212s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0.206s]
Sorting trace points...  [1.717s]
Computing alignments...  [52.466s]
Deallocating buffers...  [0.033s]
Loading trace points...  [0.178s]
Sorting trace points...  [1.891s]
Computing alignments...  [54.377s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.074s]
Sorting trace points...  [2.172s]
Computing alignments...  [53.987s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0s]
Sorting trace points...  [0.629s]
Computing alignments...  [18.134s]
Deallocating buffers...  [0.009s]
Loading trace points...  [0s]
 [306.042s]
Deallocating reference...  [0.05s]
Loading reference sequences...  [0.076s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [1343.28s]
 [1343.28s]
Deallocating queries...  [0.037s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [3.737s]
 [4.789s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 13458.1s
Reported 1748628463 pairwise alignments, 1748628463 HSPs.
9838583 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E11_R1.fastp-trim.20230215.fq.gz complete: E11_R1.blastx.meganized.daa

Now MEGANizing E11_R1.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: E11_R1.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 100% (273.3s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.2s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (3,244.5s)
Total reads:        9,838,583
With hits:           9,838,583 
Alignments:      1,746,272,168
Assig. Taxonomy:     9,216,647
Assig. SEED:            86,589
Assig. EGGNOG:          47,382
Assig. GTDB:           313,491
Assig. EC:           1,541,304
Assig. INTERPRO2GO:    822,054
MinSupport set to: 4919
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.4s)
Min-supp. changes:       4,307
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (7.5s)
Min-supp. changes:       3,330
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (19.1s)
Binning reads Syncing
100% (0.3s)
Class. Taxonomy:            65
Class. SEED:               521
Class. EGGNOG:           1,832
Class. GTDB:                21
Class. EC:               2,454
Class. INTERPRO2GO:      7,806
Total time:  3,554s
Peak memory: 29.9 of 195.3G
MEGANization of E11_R1.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E11_R2.fastp-trim.20230215.fq.gz...
28b160aad917bd921c2a2c9905fb5359  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E11_R2.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E11_R2.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.299s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.712s]
Opening the output file...  [0s]
Loading query sequences...  [58.461s]
Masking queries...  [14.614s]
Algorithm: Double-indexed
Building query histograms...  [14.085s]
Loading reference sequences...  [29.593s]
Masking reference...  [32.043s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.337s]
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Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.364s]
Building query seed array...  [1.636s]
Computing hash join...  [5.127s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [57.582s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.821s]
Building query seed array...  [1.888s]
Computing hash join...  [5.023s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [37.229s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.631s]
Building query seed array...  [1.965s]
Computing hash join...  [4.926s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [33.297s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.961s]
Building query seed array...  [1.577s]
Computing hash join...  [4.959s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [28.151s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.967s]
Building query seed array...  [1.444s]
Computing hash join...  [4.812s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [29.949s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.258s]
Building query seed array...  [1.693s]
Computing hash join...  [4.883s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [23.473s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.539s]
Building query seed array...  [1.814s]
Computing hash join...  [4.849s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [26.753s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.676s]
Building query seed array...  [1.49s]
Computing hash join...  [4.835s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [22.076s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.121s]
Clearing query masking...  [1.236s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [9.381s]
Sorting trace points...  [1.657s]
Computing alignments...  [43.245s]
Deallocating buffers...  [0.019s]
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Sorting trace points...  [1.41s]
Computing alignments...  [43.364s]
Deallocating buffers...  [0.028s]
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Sorting trace points...  [1.492s]
Computing alignments...  [43.31s]
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Sorting trace points...  [1.35s]
Computing alignments...  [42.892s]
Deallocating buffers...  [0.02s]
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Sorting trace points...  [1.701s]
Computing alignments...  [45.789s]
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Sorting trace points...  [1.806s]
Computing alignments...  [46.866s]
Deallocating buffers...  [0.02s]
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Sorting trace points...  [1.733s]
Computing alignments...  [46.685s]
Deallocating buffers...  [0.025s]
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Computing alignments...  [46.655s]
Deallocating buffers...  [0.026s]
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 [382.224s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [33.836s]
Masking reference...  [31.283s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.332s]
Allocating buffers...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.274s]
Building query seed array...  [1.644s]
Computing hash join...  [5s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [53.997s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.398s]
Building query seed array...  [1.866s]
Computing hash join...  [4.961s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [35.723s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.35s]
Building query seed array...  [1.992s]
Computing hash join...  [4.974s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [31.329s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.339s]
Building query seed array...  [1.589s]
Computing hash join...  [4.994s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [27.694s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.023s]
Building query seed array...  [1.458s]
Computing hash join...  [4.894s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [30.371s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.378s]
Building query seed array...  [1.703s]
Computing hash join...  [4.814s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [23.864s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.428s]
Building query seed array...  [1.863s]
Computing hash join...  [4.771s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [24.666s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.939s]
Building query seed array...  [1.463s]
Computing hash join...  [4.788s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [21.931s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.121s]
Clearing query masking...  [1.2s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [9.586s]
Sorting trace points...  [1.678s]
Computing alignments...  [43.141s]
Deallocating buffers...  [0.02s]
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Sorting trace points...  [1.621s]
Computing alignments...  [42.93s]
Deallocating buffers...  [0.023s]
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Sorting trace points...  [1.322s]
Computing alignments...  [43.218s]
Deallocating buffers...  [0.022s]
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Sorting trace points...  [1.674s]
Computing alignments...  [42.743s]
Deallocating buffers...  [0.019s]
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Sorting trace points...  [1.332s]
Computing alignments...  [45.593s]
Deallocating buffers...  [0.022s]
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Sorting trace points...  [1.437s]
Computing alignments...  [46.698s]
Deallocating buffers...  [0.023s]
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Sorting trace points...  [1.582s]
Computing alignments...  [46.491s]
Deallocating buffers...  [0.028s]
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Sorting trace points...  [1.378s]
Computing alignments...  [46.454s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
 [381.006s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [29.855s]
Masking reference...  [30.895s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.786s]
Allocating buffers...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [9.879s]
Building query seed array...  [1.653s]
Computing hash join...  [5.103s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [58.139s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.879s]
Building query seed array...  [1.881s]
Computing hash join...  [4.993s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [34.581s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.412s]
Building query seed array...  [1.958s]
Computing hash join...  [4.931s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [32.45s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.511s]
Building query seed array...  [1.587s]
Computing hash join...  [4.934s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [28.294s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.778s]
Building query seed array...  [1.481s]
Computing hash join...  [4.819s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [30.503s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.077s]
Building query seed array...  [1.702s]
Computing hash join...  [4.855s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [23.32s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.652s]
Building query seed array...  [1.803s]
Computing hash join...  [4.741s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [25.575s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.796s]
Building query seed array...  [1.477s]
Computing hash join...  [4.846s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [23.123s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.218s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [9.252s]
Sorting trace points...  [1.712s]
Computing alignments...  [43.209s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.129s]
Sorting trace points...  [1.704s]
Computing alignments...  [43.005s]
Deallocating buffers...  [0.032s]
Loading trace points...  [0.128s]
Sorting trace points...  [1.643s]
Computing alignments...  [43.268s]
Deallocating buffers...  [0.019s]
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Sorting trace points...  [1.683s]
Computing alignments...  [42.819s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.127s]
Sorting trace points...  [1.804s]
Computing alignments...  [45.687s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.163s]
Sorting trace points...  [1.466s]
Computing alignments...  [46.917s]
Deallocating buffers...  [0.022s]
Loading trace points...  [1.008s]
Sorting trace points...  [1.626s]
Computing alignments...  [46.813s]
Deallocating buffers...  [0.021s]
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Computing alignments...  [46.77s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
 [382.772s]
Deallocating reference...  [0.063s]
Loading reference sequences...  [29.664s]
Masking reference...  [32.094s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.274s]
Allocating buffers...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.326s]
Building query seed array...  [1.599s]
Computing hash join...  [4.988s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [56.079s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.398s]
Building query seed array...  [1.897s]
Computing hash join...  [4.989s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [36.337s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.032s]
Building query seed array...  [1.968s]
Computing hash join...  [4.948s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [32.709s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.09s]
Building query seed array...  [1.607s]
Computing hash join...  [5.006s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [27.829s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.921s]
Building query seed array...  [1.444s]
Computing hash join...  [4.827s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [31.034s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.951s]
Building query seed array...  [1.761s]
Computing hash join...  [4.856s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [23.28s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.059s]
Building query seed array...  [1.847s]
Computing hash join...  [4.799s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [26.847s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.905s]
Building query seed array...  [1.532s]
Computing hash join...  [4.766s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [22.131s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.122s]
Clearing query masking...  [1.264s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [9.031s]
Sorting trace points...  [1.69s]
Computing alignments...  [42.969s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.135s]
Sorting trace points...  [1.632s]
Computing alignments...  [42.943s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.153s]
Sorting trace points...  [1.447s]
Computing alignments...  [43.294s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.111s]
Sorting trace points...  [1.621s]
Computing alignments...  [42.927s]
Deallocating buffers...  [0.021s]
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Sorting trace points...  [1.75s]
Computing alignments...  [45.572s]
Deallocating buffers...  [0.02s]
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Sorting trace points...  [1.782s]
Computing alignments...  [46.792s]
Deallocating buffers...  [0.021s]
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Sorting trace points...  [1.525s]
Computing alignments...  [46.532s]
Deallocating buffers...  [0.022s]
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Sorting trace points...  [1.472s]
Computing alignments...  [46.505s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [380.641s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [31.046s]
Masking reference...  [30.878s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.367s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.506s]
Building query seed array...  [1.592s]
Computing hash join...  [4.97s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [53.927s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.82s]
Building query seed array...  [1.849s]
Computing hash join...  [4.997s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [34.511s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.452s]
Building query seed array...  [1.982s]
Computing hash join...  [4.949s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [30.901s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.271s]
Building query seed array...  [1.648s]
Computing hash join...  [4.985s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [27.946s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.087s]
Building query seed array...  [1.464s]
Computing hash join...  [4.805s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [31.984s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.184s]
Building query seed array...  [1.709s]
Computing hash join...  [4.81s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [23.214s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.853s]
Building query seed array...  [1.824s]
Computing hash join...  [4.846s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [25.56s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.969s]
Building query seed array...  [1.463s]
Computing hash join...  [4.888s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [22.116s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.119s]
Clearing query masking...  [1.247s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [9.303s]
Sorting trace points...  [1.709s]
Computing alignments...  [43.062s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.114s]
Sorting trace points...  [1.303s]
Computing alignments...  [42.808s]
Deallocating buffers...  [0.026s]
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Sorting trace points...  [1.516s]
Computing alignments...  [43.022s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.129s]
Sorting trace points...  [1.601s]
Computing alignments...  [42.647s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.12s]
Sorting trace points...  [1.722s]
Computing alignments...  [45.413s]
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Sorting trace points...  [1.725s]
Computing alignments...  [46.588s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.144s]
Sorting trace points...  [1.537s]
Computing alignments...  [46.387s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.795s]
Computing alignments...  [46.523s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
 [379.691s]
Deallocating reference...  [0.063s]
Loading reference sequences...  [29.62s]
Masking reference...  [30.858s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.716s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.543s]
Building query seed array...  [1.657s]
Computing hash join...  [4.975s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [55.393s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.437s]
Building query seed array...  [1.848s]
Computing hash join...  [4.984s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [35.045s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.432s]
Building query seed array...  [2.006s]
Computing hash join...  [4.968s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [31.24s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.94s]
Building query seed array...  [1.622s]
Computing hash join...  [4.992s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [29.065s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.979s]
Building query seed array...  [1.456s]
Computing hash join...  [4.813s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [29.634s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.361s]
Building query seed array...  [1.717s]
Computing hash join...  [4.938s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [23.144s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.291s]
Building query seed array...  [1.788s]
Computing hash join...  [4.87s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [25.471s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.871s]
Building query seed array...  [1.443s]
Computing hash join...  [4.8s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [21.393s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.117s]
Clearing query masking...  [1.211s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [9.207s]
Sorting trace points...  [1.7s]
Computing alignments...  [42.765s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.1s]
Sorting trace points...  [1.622s]
Computing alignments...  [42.524s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.142s]
Sorting trace points...  [1.671s]
Computing alignments...  [42.85s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.647s]
Computing alignments...  [42.393s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.122s]
Sorting trace points...  [1.785s]
Computing alignments...  [45.263s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.116s]
Sorting trace points...  [1.515s]
Computing alignments...  [46.357s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.127s]
Sorting trace points...  [1.466s]
Computing alignments...  [46.081s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
Sorting trace points...  [1.351s]
Computing alignments...  [46.224s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
 [377.435s]
Deallocating reference...  [0.064s]
Loading reference sequences...  [29.356s]
Masking reference...  [32.172s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [31.758s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.449s]
Building query seed array...  [1.65s]
Computing hash join...  [4.991s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [56.831s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.467s]
Building query seed array...  [1.919s]
Computing hash join...  [5.042s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [34.913s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.25s]
Building query seed array...  [1.995s]
Computing hash join...  [4.937s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [31.121s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.457s]
Building query seed array...  [1.564s]
Computing hash join...  [4.999s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [28.115s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.807s]
Building query seed array...  [1.425s]
Computing hash join...  [4.786s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [31.76s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.266s]
Building query seed array...  [1.737s]
Computing hash join...  [4.934s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [23.556s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.175s]
Building query seed array...  [1.763s]
Computing hash join...  [4.823s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [25.967s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.829s]
Building query seed array...  [1.423s]
Computing hash join...  [4.762s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [22.178s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.189s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [9.412s]
Sorting trace points...  [1.645s]
Computing alignments...  [43.142s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.115s]
Sorting trace points...  [1.595s]
Computing alignments...  [42.917s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.127s]
Sorting trace points...  [1.315s]
Computing alignments...  [43.16s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.12s]
Sorting trace points...  [1.323s]
Computing alignments...  [42.849s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.139s]
Sorting trace points...  [1.668s]
Computing alignments...  [45.576s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.124s]
Sorting trace points...  [1.558s]
Computing alignments...  [46.769s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.162s]
Sorting trace points...  [1.673s]
Computing alignments...  [46.445s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
Sorting trace points...  [1.767s]
Computing alignments...  [46.525s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [380.403s]
Deallocating reference...  [0.063s]
Loading reference sequences...  [30.506s]
Masking reference...  [30.835s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.008s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.41s]
Building query seed array...  [1.61s]
Computing hash join...  [4.933s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [56.444s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.417s]
Building query seed array...  [1.896s]
Computing hash join...  [5.064s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [35.945s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.688s]
Building query seed array...  [2.024s]
Computing hash join...  [4.948s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [33.122s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.112s]
Building query seed array...  [1.572s]
Computing hash join...  [4.921s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [27.991s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.926s]
Building query seed array...  [1.531s]
Computing hash join...  [4.728s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [29.405s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.972s]
Building query seed array...  [1.726s]
Computing hash join...  [4.771s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [23.459s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.117s]
Building query seed array...  [1.73s]
Computing hash join...  [4.72s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [25.873s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.696s]
Building query seed array...  [1.476s]
Computing hash join...  [4.875s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [23.041s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.134s]
Clearing query masking...  [1.243s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [9.073s]
Sorting trace points...  [1.767s]
Computing alignments...  [43.243s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.118s]
Sorting trace points...  [1.306s]
Computing alignments...  [43.175s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.143s]
Sorting trace points...  [1.633s]
Computing alignments...  [43.409s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.163s]
Sorting trace points...  [1.609s]
Computing alignments...  [42.811s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.123s]
Sorting trace points...  [1.76s]
Computing alignments...  [45.76s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.156s]
Sorting trace points...  [1.784s]
Computing alignments...  [46.907s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.143s]
Sorting trace points...  [1.723s]
Computing alignments...  [46.627s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
Sorting trace points...  [1.738s]
Computing alignments...  [46.699s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0s]
 [382.117s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.613s]
Masking reference...  [32.235s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.306s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.372s]
Building query seed array...  [1.648s]
Computing hash join...  [5.037s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [57.424s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.353s]
Building query seed array...  [1.907s]
Computing hash join...  [5.055s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [36.156s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.392s]
Building query seed array...  [1.969s]
Computing hash join...  [4.98s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [31.391s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.165s]
Building query seed array...  [1.605s]
Computing hash join...  [4.971s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [27.799s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.014s]
Building query seed array...  [1.485s]
Computing hash join...  [4.787s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [30.057s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.526s]
Building query seed array...  [1.692s]
Computing hash join...  [4.812s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [23.569s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.487s]
Building query seed array...  [1.815s]
Computing hash join...  [4.74s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [26.788s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.867s]
Building query seed array...  [1.497s]
Computing hash join...  [4.858s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [22.338s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.188s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [9.167s]
Sorting trace points...  [1.701s]
Computing alignments...  [43.439s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.107s]
Sorting trace points...  [1.299s]
Computing alignments...  [42.994s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.126s]
Sorting trace points...  [1.666s]
Computing alignments...  [43.288s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.169s]
Sorting trace points...  [1.326s]
Computing alignments...  [42.858s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.139s]
Sorting trace points...  [1.709s]
Computing alignments...  [45.562s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.12s]
Sorting trace points...  [1.781s]
Computing alignments...  [46.775s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.134s]
Sorting trace points...  [1.454s]
Computing alignments...  [46.539s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
Sorting trace points...  [1.512s]
Computing alignments...  [46.633s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
 [380.762s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [33.918s]
Masking reference...  [31.679s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.122s]
Allocating buffers...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [9.903s]
Building query seed array...  [1.695s]
Computing hash join...  [4.937s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [56.748s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.281s]
Building query seed array...  [1.88s]
Computing hash join...  [4.946s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [35.34s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.089s]
Building query seed array...  [2.003s]
Computing hash join...  [4.949s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [31.911s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.98s]
Building query seed array...  [1.65s]
Computing hash join...  [4.998s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [27.818s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.151s]
Building query seed array...  [1.455s]
Computing hash join...  [4.852s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [31.234s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.741s]
Building query seed array...  [1.701s]
Computing hash join...  [4.85s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [24.234s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.022s]
Building query seed array...  [1.783s]
Computing hash join...  [4.799s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [26.081s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.941s]
Building query seed array...  [1.451s]
Computing hash join...  [4.92s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [22.171s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.121s]
Clearing query masking...  [1.274s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [9.087s]
Sorting trace points...  [1.739s]
Computing alignments...  [42.854s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.089s]
Sorting trace points...  [1.579s]
Computing alignments...  [42.953s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.112s]
Sorting trace points...  [1.653s]
Computing alignments...  [43.381s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.124s]
Sorting trace points...  [1.599s]
Computing alignments...  [42.754s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.185s]
Sorting trace points...  [1.784s]
Computing alignments...  [45.434s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.14s]
Sorting trace points...  [1.373s]
Computing alignments...  [46.729s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.181s]
Sorting trace points...  [1.404s]
Computing alignments...  [46.535s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
Sorting trace points...  [1.812s]
Computing alignments...  [46.504s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0s]
 [380.292s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [32.054s]
Masking reference...  [32.096s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.104s]
Allocating buffers...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.352s]
Building query seed array...  [1.638s]
Computing hash join...  [5.088s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [55.944s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.724s]
Building query seed array...  [1.87s]
Computing hash join...  [4.985s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [36.309s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.03s]
Building query seed array...  [1.963s]
Computing hash join...  [4.917s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [32.694s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.044s]
Building query seed array...  [1.638s]
Computing hash join...  [4.968s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [29.616s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.909s]
Building query seed array...  [1.466s]
Computing hash join...  [4.806s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [30.394s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.569s]
Building query seed array...  [1.68s]
Computing hash join...  [4.796s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [23.532s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.385s]
Building query seed array...  [1.825s]
Computing hash join...  [4.785s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [25.029s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.922s]
Building query seed array...  [1.465s]
Computing hash join...  [4.857s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [23.783s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.119s]
Clearing query masking...  [1.221s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [9.234s]
Sorting trace points...  [1.697s]
Computing alignments...  [42.885s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.11s]
Sorting trace points...  [1.672s]
Computing alignments...  [42.67s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.311s]
Computing alignments...  [43.102s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.12s]
Sorting trace points...  [1.586s]
Computing alignments...  [42.64s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.139s]
Sorting trace points...  [1.419s]
Computing alignments...  [45.249s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.133s]
Sorting trace points...  [1.771s]
Computing alignments...  [46.512s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.127s]
Sorting trace points...  [1.506s]
Computing alignments...  [46.231s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [1.755s]
Computing alignments...  [46.253s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [378.532s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [31.209s]
Masking reference...  [30.83s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.006s]
Building reference histograms...  [32.28s]
Allocating buffers...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.326s]
Building query seed array...  [1.675s]
Computing hash join...  [4.931s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [57.794s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.624s]
Building query seed array...  [1.896s]
Computing hash join...  [4.927s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [36.085s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.711s]
Building query seed array...  [2.028s]
Computing hash join...  [4.982s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [31.662s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.96s]
Building query seed array...  [1.589s]
Computing hash join...  [4.932s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [28.062s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.582s]
Building query seed array...  [1.49s]
Computing hash join...  [4.723s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [30.228s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.119s]
Building query seed array...  [1.784s]
Computing hash join...  [4.861s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [23.696s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.02s]
Building query seed array...  [1.783s]
Computing hash join...  [4.763s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [26.261s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10s]
Building query seed array...  [1.523s]
Computing hash join...  [4.808s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [22.003s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.118s]
Clearing query masking...  [1.22s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [9.052s]
Sorting trace points...  [1.761s]
Computing alignments...  [43.205s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.136s]
Sorting trace points...  [1.596s]
Computing alignments...  [42.914s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.152s]
Sorting trace points...  [1.395s]
Computing alignments...  [43.273s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.14s]
Sorting trace points...  [1.403s]
Computing alignments...  [42.768s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.169s]
Sorting trace points...  [1.731s]
Computing alignments...  [45.537s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.153s]
Sorting trace points...  [1.427s]
Computing alignments...  [46.829s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.155s]
Sorting trace points...  [1.794s]
Computing alignments...  [46.428s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.734s]
Computing alignments...  [46.62s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0s]
 [380.658s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [30.013s]
Masking reference...  [32.105s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.164s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.482s]
Building query seed array...  [1.541s]
Computing hash join...  [4.884s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [55.77s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.417s]
Building query seed array...  [1.877s]
Computing hash join...  [4.986s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [34.866s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.487s]
Building query seed array...  [2.033s]
Computing hash join...  [4.963s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [31.496s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.021s]
Building query seed array...  [1.642s]
Computing hash join...  [4.853s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [28.707s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.669s]
Building query seed array...  [1.505s]
Computing hash join...  [4.809s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [31.01s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.825s]
Building query seed array...  [1.705s]
Computing hash join...  [4.883s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [23.443s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.358s]
Building query seed array...  [1.772s]
Computing hash join...  [4.765s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [26.026s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.239s]
Building query seed array...  [1.45s]
Computing hash join...  [4.81s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [22.348s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.12s]
Clearing query masking...  [1.196s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [9.771s]
Sorting trace points...  [1.723s]
Computing alignments...  [42.96s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.129s]
Sorting trace points...  [1.666s]
Computing alignments...  [42.834s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.117s]
Sorting trace points...  [1.687s]
Computing alignments...  [43.144s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.142s]
Sorting trace points...  [1.456s]
Computing alignments...  [42.683s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.131s]
Sorting trace points...  [1.521s]
Computing alignments...  [45.431s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.135s]
Sorting trace points...  [1.823s]
Computing alignments...  [46.646s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.148s]
Sorting trace points...  [1.796s]
Computing alignments...  [46.414s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.459s]
Computing alignments...  [46.315s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0s]
 [380.406s]
Deallocating reference...  [0.07s]
Loading reference sequences...  [23.972s]
Masking reference...  [24.965s]
Initializing dictionary...  [0.063s]
Initializing temporary storage...  [0.006s]
Building reference histograms...  [27.038s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.48s]
Building query seed array...  [1.612s]
Computing hash join...  [4.07s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [43.7s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [10.126s]
Building query seed array...  [1.906s]
Computing hash join...  [4.184s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [27.311s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [10.666s]
Building query seed array...  [2.03s]
Computing hash join...  [4.076s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [26.625s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [8.219s]
Building query seed array...  [1.666s]
Computing hash join...  [4.168s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [23.333s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [8.357s]
Building query seed array...  [1.428s]
Computing hash join...  [3.987s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [23.905s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [9.834s]
Building query seed array...  [1.728s]
Computing hash join...  [4.056s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [19.922s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [10.512s]
Building query seed array...  [1.8s]
Computing hash join...  [3.931s]
Masking low complexity seeds...  [0.199s]
Searching alignments...  [20.924s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [8.062s]
Building query seed array...  [1.489s]
Computing hash join...  [3.957s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [18.052s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.1s]
Clearing query masking...  [1.236s]
Opening temporary output file...  [0.03s]
Computing alignments... Loading trace points...  [11.878s]
Sorting trace points...  [2.043s]
Computing alignments...  [51.426s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.281s]
Sorting trace points...  [2.098s]
Computing alignments...  [51.586s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.135s]
Sorting trace points...  [1.761s]
Computing alignments...  [52.048s]
Deallocating buffers...  [0.034s]
Loading trace points...  [0.237s]
Sorting trace points...  [2.245s]
Computing alignments...  [55.829s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.001s]
Sorting trace points...  [2.192s]
Computing alignments...  [55.372s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0s]
Sorting trace points...  [0.743s]
Computing alignments...  [18.526s]
Deallocating buffers...  [0.011s]
Loading trace points...  [0s]
 [308.84s]
Deallocating reference...  [0.051s]
Loading reference sequences...  [0.068s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [1339.9s]
 [1339.9s]
Deallocating queries...  [0.042s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [3.911s]
 [5.5s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 13553.8s
Reported 1695251984 pairwise alignments, 1695251984 HSPs.
10152440 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E11_R2.fastp-trim.20230215.fq.gz complete: E11_R2.blastx.meganized.daa

Now MEGANizing E11_R2.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: E11_R2.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 100% (269.1s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.2s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (3,185.1s)
Total reads:       10,152,440
With hits:          10,152,440 
Alignments:      1,693,714,287
Assig. Taxonomy:     9,480,066
Assig. SEED:            83,957
Assig. EGGNOG:          46,651
Assig. GTDB:           304,529
Assig. EC:           1,582,523
Assig. INTERPRO2GO:    822,921
MinSupport set to: 5076
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.4s)
Min-supp. changes:       4,404
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (8.2s)
Min-supp. changes:       3,497
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (16.9s)
Binning reads Syncing
100% (0.4s)
Class. Taxonomy:            62
Class. SEED:               512
Class. EGGNOG:           1,813
Class. GTDB:                21
Class. EC:               2,439
Class. INTERPRO2GO:      7,890
Total time:  3,489s
Peak memory: 38.3 of 195.3G
MEGANization of E11_R2.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E12_R1.fastp-trim.20230215.fq.gz...
24d6f5e25560f364c9107040cbb34969  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E12_R1.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E12_R1.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.307s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.711s]
Opening the output file...  [0s]
Loading query sequences...  [84.914s]
Masking queries...  [21.864s]
Algorithm: Double-indexed
Building query histograms...  [23.954s]
Loading reference sequences...  [29.396s]
Masking reference...  [31.258s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.228s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.152s]
Building query seed array...  [2.341s]
Computing hash join...  [5.39s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [96.301s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [13.074s]
Building query seed array...  [2.705s]
Computing hash join...  [5.348s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [58.723s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.512s]
Building query seed array...  [2.86s]
Computing hash join...  [5.209s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [52.913s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.098s]
Building query seed array...  [2.461s]
Computing hash join...  [5.216s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [46.749s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.201s]
Building query seed array...  [2.126s]
Computing hash join...  [5.066s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [47.975s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.489s]
Building query seed array...  [2.482s]
Computing hash join...  [5.006s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [36.259s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.187s]
Building query seed array...  [2.601s]
Computing hash join...  [5.04s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [40.416s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.095s]
Building query seed array...  [2.222s]
Computing hash join...  [4.932s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [35.865s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.134s]
Clearing query masking...  [1.832s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.104s]
Sorting trace points...  [1.416s]
Computing alignments...  [36.467s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.095s]
Sorting trace points...  [1.204s]
Computing alignments...  [36.611s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.357s]
Computing alignments...  [36.587s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.357s]
Computing alignments...  [36.794s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.023s]
Computing alignments...  [37.276s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.432s]
Computing alignments...  [37.174s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.403s]
Computing alignments...  [36.939s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.375s]
Computing alignments...  [36.352s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.403s]
Computing alignments...  [37.391s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.343s]
Computing alignments...  [37.803s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.401s]
Computing alignments...  [37.935s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.242s]
Sorting trace points...  [1.389s]
Computing alignments...  [37.904s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.455s]
Computing alignments...  [37.788s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.059s]
Computing alignments...  [37.935s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.111s]
Sorting trace points...  [1.417s]
Computing alignments...  [38.043s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.435s]
Computing alignments...  [37.616s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [626.742s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [31.21s]
Masking reference...  [30.868s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.236s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.189s]
Building query seed array...  [2.41s]
Computing hash join...  [5.263s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [93.357s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.447s]
Building query seed array...  [2.782s]
Computing hash join...  [5.199s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [58.503s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [14.084s]
Building query seed array...  [2.881s]
Computing hash join...  [5.186s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [49.944s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.29s]
Building query seed array...  [2.304s]
Computing hash join...  [5.2s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [45.129s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.862s]
Building query seed array...  [2.137s]
Computing hash join...  [5.081s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [46.217s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.213s]
Building query seed array...  [2.493s]
Computing hash join...  [4.973s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [37.722s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.004s]
Building query seed array...  [2.634s]
Computing hash join...  [4.906s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [39.576s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.244s]
Building query seed array...  [2.175s]
Computing hash join...  [4.954s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [35.239s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.131s]
Clearing query masking...  [1.829s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.075s]
Sorting trace points...  [1.453s]
Computing alignments...  [36.105s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.325s]
Computing alignments...  [36.334s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.39s]
Computing alignments...  [36.364s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.152s]
Sorting trace points...  [1.348s]
Computing alignments...  [36.449s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.434s]
Computing alignments...  [36.929s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.384s]
Computing alignments...  [36.825s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.323s]
Computing alignments...  [36.688s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.39s]
Computing alignments...  [36.124s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.384s]
Computing alignments...  [37.166s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.305s]
Computing alignments...  [37.656s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.412s]
Computing alignments...  [37.736s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.383s]
Computing alignments...  [37.784s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.453s]
Computing alignments...  [37.592s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.112s]
Computing alignments...  [37.723s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.473s]
Computing alignments...  [37.775s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.415s]
Computing alignments...  [37.48s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [623.123s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [29.846s]
Masking reference...  [30.919s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [33.214s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.492s]
Building query seed array...  [2.334s]
Computing hash join...  [5.261s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [96.166s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.043s]
Building query seed array...  [2.758s]
Computing hash join...  [5.318s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [57.287s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.098s]
Building query seed array...  [2.844s]
Computing hash join...  [5.171s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [53.311s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.126s]
Building query seed array...  [2.367s]
Computing hash join...  [5.164s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [46.722s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.976s]
Building query seed array...  [2.127s]
Computing hash join...  [5.041s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [48.385s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.2s]
Building query seed array...  [2.523s]
Computing hash join...  [4.915s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [36.669s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.088s]
Building query seed array...  [2.656s]
Computing hash join...  [4.9s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [40.649s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.868s]
Building query seed array...  [2.222s]
Computing hash join...  [5.001s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [36.381s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.127s]
Clearing query masking...  [1.792s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.1s]
Sorting trace points...  [1.452s]
Computing alignments...  [36.222s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.211s]
Computing alignments...  [36.427s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.099s]
Computing alignments...  [36.442s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.385s]
Computing alignments...  [36.562s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.371s]
Computing alignments...  [37.188s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.444s]
Computing alignments...  [37.017s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.428s]
Computing alignments...  [36.758s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.089s]
Sorting trace points...  [1.376s]
Computing alignments...  [36.154s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.399s]
Computing alignments...  [37.322s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.113s]
Sorting trace points...  [1.325s]
Computing alignments...  [37.771s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.42s]
Computing alignments...  [37.834s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.168s]
Computing alignments...  [37.84s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.25s]
Computing alignments...  [37.69s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.102s]
Computing alignments...  [37.806s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.111s]
Sorting trace points...  [1.411s]
Computing alignments...  [37.959s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.404s]
Computing alignments...  [37.601s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [624.333s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.375s]
Masking reference...  [30.864s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.049s]
Allocating buffers...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [9.933s]
Building query seed array...  [2.382s]
Computing hash join...  [5.221s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [91.24s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.909s]
Building query seed array...  [2.803s]
Computing hash join...  [5.243s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [58.854s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.831s]
Building query seed array...  [2.944s]
Computing hash join...  [5.221s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [52.278s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.475s]
Building query seed array...  [2.387s]
Computing hash join...  [5.287s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [45.207s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.783s]
Building query seed array...  [2.143s]
Computing hash join...  [5.051s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [46.19s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.786s]
Building query seed array...  [2.491s]
Computing hash join...  [5.037s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [36.192s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.8s]
Building query seed array...  [2.667s]
Computing hash join...  [4.973s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [39.579s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.929s]
Building query seed array...  [2.184s]
Computing hash join...  [5.066s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [35.223s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.145s]
Clearing query masking...  [1.835s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.089s]
Sorting trace points...  [1.456s]
Computing alignments...  [37.16s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.397s]
Computing alignments...  [36.386s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.087s]
Sorting trace points...  [1.034s]
Computing alignments...  [36.432s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.085s]
Sorting trace points...  [1.349s]
Computing alignments...  [36.515s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.366s]
Computing alignments...  [37.115s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.446s]
Computing alignments...  [36.969s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.397s]
Computing alignments...  [36.882s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.36s]
Computing alignments...  [36.199s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.15s]
Sorting trace points...  [1.447s]
Computing alignments...  [37.292s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.428s]
Computing alignments...  [37.789s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.169s]
Computing alignments...  [37.986s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.406s]
Computing alignments...  [37.917s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.101s]
Sorting trace points...  [1.211s]
Computing alignments...  [37.68s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.533s]
Computing alignments...  [37.975s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.32s]
Computing alignments...  [37.948s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.441s]
Computing alignments...  [37.651s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [626.126s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [31.284s]
Masking reference...  [32.089s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.423s]
Allocating buffers...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.196s]
Building query seed array...  [2.405s]
Computing hash join...  [5.243s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [92.369s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.332s]
Building query seed array...  [2.722s]
Computing hash join...  [5.239s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [56.37s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.303s]
Building query seed array...  [2.93s]
Computing hash join...  [5.187s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [52.406s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.34s]
Building query seed array...  [2.386s]
Computing hash join...  [5.244s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [46.505s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.266s]
Building query seed array...  [2.11s]
Computing hash join...  [4.956s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [46.36s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.052s]
Building query seed array...  [2.368s]
Computing hash join...  [5.004s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [36.295s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.708s]
Building query seed array...  [2.527s]
Computing hash join...  [4.954s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [40.219s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.233s]
Building query seed array...  [2.132s]
Computing hash join...  [4.977s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [35.619s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.82s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.144s]
Sorting trace points...  [1.463s]
Computing alignments...  [36.102s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.156s]
Computing alignments...  [36.312s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.393s]
Computing alignments...  [36.333s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.375s]
Computing alignments...  [36.527s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.228s]
Computing alignments...  [37.002s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.072s]
Computing alignments...  [37.032s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.386s]
Computing alignments...  [36.848s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.047s]
Computing alignments...  [36.218s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.472s]
Computing alignments...  [37.299s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.498s]
Sorting trace points...  [1.371s]
Computing alignments...  [37.81s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.444s]
Computing alignments...  [37.75s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.429s]
Computing alignments...  [37.694s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.418s]
Sorting trace points...  [1.145s]
Computing alignments...  [37.509s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.113s]
Sorting trace points...  [1.056s]
Computing alignments...  [37.716s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.392s]
Computing alignments...  [37.829s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.223s]
Computing alignments...  [37.45s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
 [623.241s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [244.229s]
Masking reference...  [30.856s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.73s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.238s]
Building query seed array...  [2.407s]
Computing hash join...  [5.214s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [90.103s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.593s]
Building query seed array...  [2.763s]
Computing hash join...  [5.19s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [56.867s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.414s]
Building query seed array...  [2.924s]
Computing hash join...  [5.261s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [49.837s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.164s]
Building query seed array...  [2.344s]
Computing hash join...  [5.146s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [44.866s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.057s]
Building query seed array...  [2.126s]
Computing hash join...  [5.045s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [44.985s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.104s]
Building query seed array...  [2.514s]
Computing hash join...  [5.037s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [35.957s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.97s]
Building query seed array...  [2.612s]
Computing hash join...  [4.936s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [39.106s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.063s]
Building query seed array...  [2.194s]
Computing hash join...  [4.931s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [34.486s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.794s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [7.288s]
Sorting trace points...  [1.394s]
Computing alignments...  [36.051s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.37s]
Computing alignments...  [36.218s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.061s]
Computing alignments...  [36.282s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.346s]
Computing alignments...  [36.248s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.395s]
Computing alignments...  [36.77s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.042s]
Computing alignments...  [36.727s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.094s]
Computing alignments...  [36.522s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.147s]
Computing alignments...  [35.949s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.389s]
Computing alignments...  [37.064s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.413s]
Computing alignments...  [37.621s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.461s]
Computing alignments...  [37.587s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.127s]
Computing alignments...  [37.6s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.506s]
Computing alignments...  [37.422s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.422s]
Computing alignments...  [37.676s]
Deallocating buffers...  [0.017s]
Loading trace points...  [1.123s]
Sorting trace points...  [1.4s]
Computing alignments...  [37.691s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.405s]
Computing alignments...  [37.382s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [621.305s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [30.813s]
Masking reference...  [30.853s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.543s]
Allocating buffers...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.487s]
Building query seed array...  [2.383s]
Computing hash join...  [5.209s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [94.396s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.467s]
Building query seed array...  [2.797s]
Computing hash join...  [5.221s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [57.645s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.515s]
Building query seed array...  [2.897s]
Computing hash join...  [5.143s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [51.973s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.416s]
Building query seed array...  [2.306s]
Computing hash join...  [5.277s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [46.741s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.364s]
Building query seed array...  [2.099s]
Computing hash join...  [5.102s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [46.12s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.284s]
Building query seed array...  [2.545s]
Computing hash join...  [5.002s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [37.349s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.751s]
Building query seed array...  [2.543s]
Computing hash join...  [5.005s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [41.929s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.204s]
Building query seed array...  [2.092s]
Computing hash join...  [4.999s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [35.349s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.128s]
Clearing query masking...  [1.838s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [7.114s]
Sorting trace points...  [1.453s]
Computing alignments...  [36.287s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.084s]
Sorting trace points...  [1.414s]
Computing alignments...  [36.418s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.171s]
Computing alignments...  [36.538s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.39s]
Computing alignments...  [36.557s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.786s]
Sorting trace points...  [1.364s]
Computing alignments...  [37.084s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.426s]
Computing alignments...  [37.009s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.18s]
Computing alignments...  [36.904s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.35s]
Computing alignments...  [36.238s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.037s]
Computing alignments...  [37.377s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.399s]
Computing alignments...  [37.695s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.134s]
Computing alignments...  [37.836s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.47s]
Computing alignments...  [37.826s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.435s]
Computing alignments...  [37.542s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.085s]
Sorting trace points...  [1.463s]
Computing alignments...  [37.807s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.085s]
Computing alignments...  [37.891s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.459s]
Computing alignments...  [37.655s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [625.013s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.745s]
Masking reference...  [32.041s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.805s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.408s]
Building query seed array...  [2.344s]
Computing hash join...  [5.237s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [92.472s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.553s]
Building query seed array...  [2.754s]
Computing hash join...  [5.267s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [58.944s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.523s]
Building query seed array...  [2.988s]
Computing hash join...  [5.262s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [51.755s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.371s]
Building query seed array...  [2.284s]
Computing hash join...  [5.171s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [45.318s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.215s]
Building query seed array...  [2.128s]
Computing hash join...  [4.982s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [46.142s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.294s]
Building query seed array...  [2.482s]
Computing hash join...  [5.075s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [36.158s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.386s]
Building query seed array...  [2.546s]
Computing hash join...  [5.074s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [40.714s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.88s]
Building query seed array...  [2.104s]
Computing hash join...  [4.992s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [35.482s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.165s]
Clearing query masking...  [1.823s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [7.092s]
Sorting trace points...  [1.367s]
Computing alignments...  [36.266s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.144s]
Computing alignments...  [36.563s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.404s]
Computing alignments...  [36.448s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.405s]
Computing alignments...  [36.629s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.098s]
Sorting trace points...  [1.449s]
Computing alignments...  [37.138s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.39s]
Computing alignments...  [37.044s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.09s]
Sorting trace points...  [1.372s]
Computing alignments...  [36.95s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.209s]
Computing alignments...  [36.281s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.424s]
Computing alignments...  [37.451s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.158s]
Computing alignments...  [37.905s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.464s]
Computing alignments...  [38.031s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.089s]
Computing alignments...  [37.932s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.473s]
Computing alignments...  [37.749s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.461s]
Computing alignments...  [38.032s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.087s]
Sorting trace points...  [1.373s]
Computing alignments...  [38.089s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.415s]
Computing alignments...  [37.692s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [626.251s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [31.695s]
Masking reference...  [31.411s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.986s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.102s]
Building query seed array...  [2.395s]
Computing hash join...  [5.295s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [95.548s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.359s]
Building query seed array...  [2.768s]
Computing hash join...  [5.19s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [57.121s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.815s]
Building query seed array...  [2.977s]
Computing hash join...  [5.203s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [53.17s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.07s]
Building query seed array...  [2.311s]
Computing hash join...  [5.188s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [46.467s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.82s]
Building query seed array...  [2.145s]
Computing hash join...  [5.02s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [46.69s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.195s]
Building query seed array...  [2.446s]
Computing hash join...  [5.119s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [37.391s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.277s]
Building query seed array...  [2.623s]
Computing hash join...  [4.979s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [41.137s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.057s]
Building query seed array...  [2.139s]
Computing hash join...  [4.974s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [36.529s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.134s]
Clearing query masking...  [1.853s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.081s]
Sorting trace points...  [1.399s]
Computing alignments...  [36.277s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.275s]
Computing alignments...  [36.561s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.417s]
Computing alignments...  [36.423s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.279s]
Computing alignments...  [36.545s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.369s]
Computing alignments...  [37.113s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.439s]
Computing alignments...  [37.047s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.351s]
Computing alignments...  [36.938s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.275s]
Computing alignments...  [36.212s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.442s]
Computing alignments...  [37.365s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.257s]
Computing alignments...  [37.735s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.474s]
Computing alignments...  [37.891s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.039s]
Sorting trace points...  [1.426s]
Computing alignments...  [37.787s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.476s]
Computing alignments...  [37.574s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.452s]
Computing alignments...  [37.878s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.113s]
Sorting trace points...  [1.44s]
Computing alignments...  [38.006s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.428s]
Computing alignments...  [37.734s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [625.611s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [31.248s]
Masking reference...  [31.075s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.803s]
Allocating buffers...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.342s]
Building query seed array...  [2.398s]
Computing hash join...  [5.161s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [94.552s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.627s]
Building query seed array...  [2.799s]
Computing hash join...  [5.264s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [58.159s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.094s]
Building query seed array...  [2.924s]
Computing hash join...  [5.136s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [52.311s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.244s]
Building query seed array...  [2.344s]
Computing hash join...  [5.181s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [46.134s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.987s]
Building query seed array...  [2.17s]
Computing hash join...  [5.009s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [46.384s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.393s]
Building query seed array...  [2.423s]
Computing hash join...  [5.042s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [36.898s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.132s]
Building query seed array...  [2.643s]
Computing hash join...  [4.939s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [41.011s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.181s]
Building query seed array...  [2.144s]
Computing hash join...  [4.956s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [35.293s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.794s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [7.079s]
Sorting trace points...  [1.424s]
Computing alignments...  [36.311s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.353s]
Computing alignments...  [36.543s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.017s]
Computing alignments...  [36.532s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.375s]
Computing alignments...  [36.616s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.422s]
Computing alignments...  [37.123s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.435s]
Computing alignments...  [37.055s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.363s]
Computing alignments...  [36.953s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.181s]
Computing alignments...  [36.199s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.436s]
Computing alignments...  [37.472s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.414s]
Computing alignments...  [37.779s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.425s]
Computing alignments...  [37.944s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.386s]
Computing alignments...  [37.819s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.444s]
Computing alignments...  [37.597s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.445s]
Computing alignments...  [37.867s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.4s]
Computing alignments...  [37.843s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.165s]
Computing alignments...  [37.617s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [625.291s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [35.927s]
Masking reference...  [31.206s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.91s]
Allocating buffers...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.615s]
Building query seed array...  [2.326s]
Computing hash join...  [5.185s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [93.016s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.134s]
Building query seed array...  [2.734s]
Computing hash join...  [5.221s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [56.085s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.591s]
Building query seed array...  [2.954s]
Computing hash join...  [5.143s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [52.145s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.077s]
Building query seed array...  [2.328s]
Computing hash join...  [5.229s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [46.072s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.853s]
Building query seed array...  [2.123s]
Computing hash join...  [5.033s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [46.574s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.887s]
Building query seed array...  [2.454s]
Computing hash join...  [5.031s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [37.634s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.45s]
Building query seed array...  [2.548s]
Computing hash join...  [4.995s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [40.566s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.727s]
Building query seed array...  [2.088s]
Computing hash join...  [5.035s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [35.855s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.782s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.057s]
Sorting trace points...  [1.376s]
Computing alignments...  [36.061s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.225s]
Computing alignments...  [36.392s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.371s]
Computing alignments...  [36.325s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.017s]
Computing alignments...  [36.349s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.411s]
Computing alignments...  [37.056s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.074s]
Computing alignments...  [36.919s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.032s]
Sorting trace points...  [1.266s]
Computing alignments...  [36.884s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.344s]
Computing alignments...  [36.058s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.084s]
Sorting trace points...  [1.326s]
Computing alignments...  [37.195s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.357s]
Computing alignments...  [37.612s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.396s]
Computing alignments...  [37.755s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.405s]
Computing alignments...  [37.672s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.208s]
Computing alignments...  [37.399s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.129s]
Computing alignments...  [37.613s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.354s]
Computing alignments...  [37.673s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.405s]
Computing alignments...  [37.503s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [621.385s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [29.412s]
Masking reference...  [30.841s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [33.339s]
Allocating buffers...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.101s]
Building query seed array...  [2.341s]
Computing hash join...  [5.202s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [92.858s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.332s]
Building query seed array...  [2.803s]
Computing hash join...  [5.257s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [59.301s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.685s]
Building query seed array...  [2.878s]
Computing hash join...  [5.198s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [52.563s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.224s]
Building query seed array...  [2.329s]
Computing hash join...  [5.153s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [47.2s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.193s]
Building query seed array...  [2.077s]
Computing hash join...  [4.951s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [46.331s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.078s]
Building query seed array...  [2.409s]
Computing hash join...  [5.022s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [36.467s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.028s]
Building query seed array...  [2.58s]
Computing hash join...  [5.047s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [40.463s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.174s]
Building query seed array...  [2.151s]
Computing hash join...  [4.985s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [35.29s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.146s]
Clearing query masking...  [1.819s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.503s]
Sorting trace points...  [1.419s]
Computing alignments...  [36.292s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.208s]
Computing alignments...  [36.643s]
Deallocating buffers...  [0.024s]
Loading trace points...  [1.028s]
Sorting trace points...  [1.082s]
Computing alignments...  [36.593s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.396s]
Computing alignments...  [36.629s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.229s]
Computing alignments...  [37.166s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.205s]
Computing alignments...  [37.153s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.205s]
Computing alignments...  [36.943s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.351s]
Computing alignments...  [36.24s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.385s]
Computing alignments...  [37.455s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.084s]
Sorting trace points...  [1.43s]
Computing alignments...  [37.92s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.092s]
Sorting trace points...  [1.454s]
Computing alignments...  [37.985s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.463s]
Computing alignments...  [37.95s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.082s]
Computing alignments...  [37.811s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.402s]
Computing alignments...  [37.919s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.108s]
Sorting trace points...  [1.095s]
Computing alignments...  [37.951s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.42s]
Computing alignments...  [37.609s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [626.906s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [29.638s]
Masking reference...  [32.03s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.439s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.051s]
Building query seed array...  [2.349s]
Computing hash join...  [5.219s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [96.962s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.642s]
Building query seed array...  [2.801s]
Computing hash join...  [5.267s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [58.566s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.098s]
Building query seed array...  [2.967s]
Computing hash join...  [5.149s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [50.643s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.349s]
Building query seed array...  [2.395s]
Computing hash join...  [5.199s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [45.039s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.893s]
Building query seed array...  [2.168s]
Computing hash join...  [5.074s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [46.653s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.429s]
Building query seed array...  [2.451s]
Computing hash join...  [4.988s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [36.413s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.348s]
Building query seed array...  [2.614s]
Computing hash join...  [4.952s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [40.87s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.052s]
Building query seed array...  [2.122s]
Computing hash join...  [4.998s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [35.335s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.142s]
Clearing query masking...  [1.81s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.243s]
Sorting trace points...  [1.358s]
Computing alignments...  [36.152s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.429s]
Computing alignments...  [36.424s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.367s]
Computing alignments...  [36.488s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.117s]
Computing alignments...  [36.43s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.411s]
Computing alignments...  [37s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.404s]
Computing alignments...  [37.028s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.995s]
Sorting trace points...  [1.405s]
Computing alignments...  [36.997s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.068s]
Computing alignments...  [36.253s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.453s]
Computing alignments...  [37.157s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.126s]
Computing alignments...  [37.612s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.449s]
Computing alignments...  [37.803s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.442s]
Computing alignments...  [37.814s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.412s]
Computing alignments...  [37.647s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.446s]
Computing alignments...  [37.828s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.483s]
Computing alignments...  [37.959s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.026s]
Computing alignments...  [37.641s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
 [625.061s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [23.699s]
Masking reference...  [24.968s]
Initializing dictionary...  [0.063s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [27.043s]
Allocating buffers...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.472s]
Building query seed array...  [2.325s]
Computing hash join...  [4.406s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [73.402s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [10.146s]
Building query seed array...  [2.77s]
Computing hash join...  [4.425s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [47.35s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [10.732s]
Building query seed array...  [2.81s]
Computing hash join...  [4.416s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [43.691s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [8.288s]
Building query seed array...  [2.444s]
Computing hash join...  [4.402s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [38.288s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [8.375s]
Building query seed array...  [2.104s]
Computing hash join...  [4.105s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [38.401s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [10.179s]
Building query seed array...  [2.46s]
Computing hash join...  [4.169s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [29.604s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [10.589s]
Building query seed array...  [2.584s]
Computing hash join...  [4.177s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [33.464s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [8.026s]
Building query seed array...  [2.197s]
Computing hash join...  [4.19s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [28.937s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.105s]
Clearing query masking...  [1.799s]
Opening temporary output file...  [0.033s]
Computing alignments... Loading trace points...  [5.912s]
Sorting trace points...  [1.121s]
Computing alignments...  [28.946s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.111s]
Computing alignments...  [28.997s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.121s]
Computing alignments...  [29.014s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.137s]
Computing alignments...  [29.052s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.084s]
Sorting trace points...  [0.943s]
Computing alignments...  [29.46s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.128s]
Computing alignments...  [29.421s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.107s]
Computing alignments...  [29.387s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.071s]
Sorting trace points...  [0.967s]
Computing alignments...  [28.88s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.102s]
Computing alignments...  [29.723s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.102s]
Computing alignments...  [30.058s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.061s]
Sorting trace points...  [0.996s]
Computing alignments...  [30.122s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.124s]
Computing alignments...  [30.061s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.168s]
Computing alignments...  [29.96s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.183s]
Computing alignments...  [30.211s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.079s]
Sorting trace points...  [0.89s]
Computing alignments...  [30.17s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.183s]
Computing alignments...  [29.878s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [497.89s]
Deallocating reference...  [0.047s]
Loading reference sequences...  [0.091s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [2275.69s]
 [2275.69s]
Deallocating queries...  [0.058s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [3.682s]
 [4.903s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 20372.7s
Reported 3024246186 pairwise alignments, 3024246186 HSPs.
15293803 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E12_R1.fastp-trim.20230215.fq.gz complete: E12_R1.blastx.meganized.daa

Now MEGANizing E12_R1.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: E12_R1.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 100% (243.1s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.3s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (5,557.6s)
Total reads:       15,293,803
With hits:          15,293,803 
Alignments:      3,016,881,658
Assig. Taxonomy:    14,364,850
Assig. SEED:           119,052
Assig. EGGNOG:          51,042
Assig. GTDB:           455,852
Assig. EC:           2,550,049
Assig. INTERPRO2GO:  1,411,177
MinSupport set to: 7646
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.4s)
Min-supp. changes:       4,290
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (13.2s)
Min-supp. changes:       3,474
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (54.1s)
Binning reads Syncing
100% (0.4s)
Class. Taxonomy:            73
Class. SEED:               487
Class. EGGNOG:           1,725
Class. GTDB:                17
Class. EC:               2,361
Class. INTERPRO2GO:      8,094
Total time:  5,878s
Peak memory: 31.5 of 195.3G
MEGANization of E12_R1.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E12_R2.fastp-trim.20230215.fq.gz...
a97470f8557247cddf0a71f38394141f  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E12_R2.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E12_R2.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.337s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.748s]
Opening the output file...  [0s]
Loading query sequences...  [86.398s]
Masking queries...  [21.457s]
Algorithm: Double-indexed
Building query histograms...  [21.436s]
Loading reference sequences...  [30.126s]
Masking reference...  [32.036s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [31.601s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.872s]
Building query seed array...  [2.375s]
Computing hash join...  [5.472s]
Masking low complexity seeds...  [0.275s]
Searching alignments...  [90.806s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.637s]
Building query seed array...  [2.819s]
Computing hash join...  [5.429s]
Masking low complexity seeds...  [0.276s]
Searching alignments...  [60.404s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.544s]
Building query seed array...  [2.959s]
Computing hash join...  [5.419s]
Masking low complexity seeds...  [0.276s]
Searching alignments...  [52.625s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.054s]
Building query seed array...  [2.338s]
Computing hash join...  [5.398s]
Masking low complexity seeds...  [0.269s]
Searching alignments...  [47.896s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.911s]
Building query seed array...  [2.208s]
Computing hash join...  [5.098s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [51.251s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.229s]
Building query seed array...  [2.537s]
Computing hash join...  [5.174s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [37.091s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.277s]
Building query seed array...  [2.721s]
Computing hash join...  [5.117s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [45.439s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.027s]
Building query seed array...  [2.094s]
Computing hash join...  [5.199s]
Masking low complexity seeds...  [0.266s]
Searching alignments...  [37.635s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.849s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.14s]
Sorting trace points...  [1.404s]
Computing alignments...  [36.813s]
Deallocating buffers...  [0.023s]
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Sorting trace points...  [1.052s]
Computing alignments...  [36.886s]
Deallocating buffers...  [0.022s]
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Sorting trace points...  [1.1s]
Computing alignments...  [36.764s]
Deallocating buffers...  [0.018s]
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Sorting trace points...  [1.116s]
Computing alignments...  [36.46s]
Deallocating buffers...  [0.017s]
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Sorting trace points...  [1.296s]
Computing alignments...  [36.219s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.039s]
Computing alignments...  [36.085s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.185s]
Computing alignments...  [36.214s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.089s]
Sorting trace points...  [1.323s]
Computing alignments...  [36.121s]
Deallocating buffers...  [0.019s]
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Sorting trace points...  [1.189s]
Computing alignments...  [37.909s]
Deallocating buffers...  [0.018s]
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Sorting trace points...  [1.247s]
Computing alignments...  [38.797s]
Deallocating buffers...  [0.018s]
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Computing alignments...  [38.889s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.185s]
Computing alignments...  [38.875s]
Deallocating buffers...  [0.024s]
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Sorting trace points...  [1.413s]
Computing alignments...  [38.576s]
Deallocating buffers...  [0.021s]
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Sorting trace points...  [1.42s]
Computing alignments...  [39.001s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.458s]
Computing alignments...  [39.101s]
Deallocating buffers...  [0.025s]
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Sorting trace points...  [1.46s]
Computing alignments...  [38.554s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [629.834s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [30.642s]
Masking reference...  [31.654s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.428s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.309s]
Building query seed array...  [2.47s]
Computing hash join...  [5.397s]
Masking low complexity seeds...  [0.277s]
Searching alignments...  [90.487s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.257s]
Building query seed array...  [2.815s]
Computing hash join...  [5.363s]
Masking low complexity seeds...  [0.275s]
Searching alignments...  [57.888s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.399s]
Building query seed array...  [3.039s]
Computing hash join...  [5.361s]
Masking low complexity seeds...  [0.268s]
Searching alignments...  [51.983s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.039s]
Building query seed array...  [2.342s]
Computing hash join...  [5.45s]
Masking low complexity seeds...  [0.277s]
Searching alignments...  [45.399s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.124s]
Building query seed array...  [2.144s]
Computing hash join...  [5.045s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [50.188s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.553s]
Building query seed array...  [2.49s]
Computing hash join...  [5.097s]
Masking low complexity seeds...  [0.259s]
Searching alignments...  [37.333s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.48s]
Building query seed array...  [2.543s]
Computing hash join...  [5.237s]
Masking low complexity seeds...  [0.27s]
Searching alignments...  [41.645s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.385s]
Building query seed array...  [2.149s]
Computing hash join...  [5.137s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [35.49s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.141s]
Clearing query masking...  [1.802s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.121s]
Sorting trace points...  [1.42s]
Computing alignments...  [36.681s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.163s]
Computing alignments...  [36.873s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.235s]
Computing alignments...  [36.883s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.386s]
Computing alignments...  [36.524s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.355s]
Computing alignments...  [35.959s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.361s]
Computing alignments...  [36.024s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.411s]
Computing alignments...  [36.269s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.346s]
Computing alignments...  [35.957s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.484s]
Computing alignments...  [37.757s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.1s]
Sorting trace points...  [1.159s]
Computing alignments...  [38.729s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.284s]
Computing alignments...  [38.752s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.042s]
Sorting trace points...  [1.499s]
Computing alignments...  [38.69s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.529s]
Computing alignments...  [38.594s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.502s]
Computing alignments...  [38.784s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.179s]
Computing alignments...  [39.573s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0s]
Sorting trace points...  [1.483s]
Computing alignments...  [38.474s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [630.681s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [29.423s]
Masking reference...  [30.926s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [33.316s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.479s]
Building query seed array...  [2.409s]
Computing hash join...  [5.402s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [93.386s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.328s]
Building query seed array...  [2.804s]
Computing hash join...  [5.413s]
Masking low complexity seeds...  [0.278s]
Searching alignments...  [57.87s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.486s]
Building query seed array...  [2.924s]
Computing hash join...  [5.39s]
Masking low complexity seeds...  [0.283s]
Searching alignments...  [52.262s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.199s]
Building query seed array...  [2.325s]
Computing hash join...  [5.385s]
Masking low complexity seeds...  [0.276s]
Searching alignments...  [46.515s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.021s]
Building query seed array...  [2.127s]
Computing hash join...  [5.101s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [50.583s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.845s]
Building query seed array...  [2.525s]
Computing hash join...  [5.121s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [37.516s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.459s]
Building query seed array...  [2.677s]
Computing hash join...  [5.176s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [43.67s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.292s]
Building query seed array...  [2.152s]
Computing hash join...  [5.241s]
Masking low complexity seeds...  [0.271s]
Searching alignments...  [36.134s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.138s]
Clearing query masking...  [1.8s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.148s]
Sorting trace points...  [1.468s]
Computing alignments...  [36.562s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.002s]
Sorting trace points...  [1.377s]
Computing alignments...  [36.752s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.337s]
Computing alignments...  [36.673s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.41s]
Computing alignments...  [36.333s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.049s]
Computing alignments...  [35.953s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.042s]
Sorting trace points...  [1.334s]
Computing alignments...  [35.933s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.094s]
Sorting trace points...  [1.374s]
Computing alignments...  [36.116s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.253s]
Computing alignments...  [35.935s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.329s]
Computing alignments...  [37.716s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.06s]
Computing alignments...  [38.653s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.389s]
Computing alignments...  [38.747s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.225s]
Computing alignments...  [38.724s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.042s]
Sorting trace points...  [1.395s]
Computing alignments...  [38.426s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.149s]
Computing alignments...  [38.637s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.146s]
Computing alignments...  [38.949s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0s]
Sorting trace points...  [1.489s]
Computing alignments...  [38.502s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [627.662s]
Deallocating reference...  [0.063s]
Loading reference sequences...  [29.593s]
Masking reference...  [32.196s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [31.736s]
Allocating buffers...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.534s]
Building query seed array...  [2.386s]
Computing hash join...  [5.292s]
Masking low complexity seeds...  [0.274s]
Searching alignments...  [91.13s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.357s]
Building query seed array...  [2.782s]
Computing hash join...  [5.37s]
Masking low complexity seeds...  [0.272s]
Searching alignments...  [58.005s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.454s]
Building query seed array...  [2.993s]
Computing hash join...  [5.355s]
Masking low complexity seeds...  [0.276s]
Searching alignments...  [51.814s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.04s]
Building query seed array...  [2.357s]
Computing hash join...  [5.3s]
Masking low complexity seeds...  [0.267s]
Searching alignments...  [45.312s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.065s]
Building query seed array...  [2.132s]
Computing hash join...  [5.105s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [50.306s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.898s]
Building query seed array...  [2.532s]
Computing hash join...  [5.088s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [37.258s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.92s]
Building query seed array...  [2.571s]
Computing hash join...  [5.075s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [43.508s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.806s]
Building query seed array...  [2.238s]
Computing hash join...  [5.017s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [35.84s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.137s]
Clearing query masking...  [1.84s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.044s]
Sorting trace points...  [1.49s]
Computing alignments...  [36.44s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.4s]
Computing alignments...  [36.718s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.074s]
Computing alignments...  [36.53s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.175s]
Computing alignments...  [36.319s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.379s]
Computing alignments...  [35.91s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.034s]
Computing alignments...  [35.918s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.075s]
Sorting trace points...  [0.999s]
Computing alignments...  [36.038s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.065s]
Computing alignments...  [35.929s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.292s]
Computing alignments...  [37.736s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.476s]
Computing alignments...  [38.733s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.336s]
Computing alignments...  [38.637s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.466s]
Computing alignments...  [38.651s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.516s]
Computing alignments...  [38.426s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.125s]
Computing alignments...  [38.814s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.197s]
Computing alignments...  [38.99s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0s]
Sorting trace points...  [1.462s]
Computing alignments...  [38.419s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [626.979s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [245.545s]
Masking reference...  [31.54s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.026s]
Allocating buffers...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.026s]
Building query seed array...  [2.388s]
Computing hash join...  [5.387s]
Masking low complexity seeds...  [0.276s]
Searching alignments...  [91.286s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.147s]
Building query seed array...  [2.689s]
Computing hash join...  [5.371s]
Masking low complexity seeds...  [0.271s]
Searching alignments...  [57.665s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.38s]
Building query seed array...  [2.895s]
Computing hash join...  [5.275s]
Masking low complexity seeds...  [0.267s]
Searching alignments...  [51.326s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.379s]
Building query seed array...  [2.372s]
Computing hash join...  [5.351s]
Masking low complexity seeds...  [0.278s]
Searching alignments...  [46.317s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.362s]
Building query seed array...  [2.132s]
Computing hash join...  [5.151s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [49.886s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.276s]
Building query seed array...  [2.502s]
Computing hash join...  [5.04s]
Masking low complexity seeds...  [0.249s]
Searching alignments...  [37.824s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.174s]
Building query seed array...  [2.51s]
Computing hash join...  [5.129s]
Masking low complexity seeds...  [0.273s]
Searching alignments...  [42.401s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.817s]
Building query seed array...  [2.125s]
Computing hash join...  [5.038s]
Masking low complexity seeds...  [0.266s]
Searching alignments...  [35.523s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.817s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [7.181s]
Sorting trace points...  [1.417s]
Computing alignments...  [36.353s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.289s]
Sorting trace points...  [1.226s]
Computing alignments...  [36.702s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.36s]
Computing alignments...  [36.506s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.096s]
Sorting trace points...  [1.402s]
Computing alignments...  [36.222s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.036s]
Sorting trace points...  [1.414s]
Computing alignments...  [35.882s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.356s]
Computing alignments...  [35.842s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.092s]
Sorting trace points...  [1.367s]
Computing alignments...  [36.057s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.352s]
Computing alignments...  [35.846s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.19s]
Computing alignments...  [37.713s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.43s]
Computing alignments...  [38.664s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.039s]
Sorting trace points...  [1.449s]
Computing alignments...  [38.678s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.165s]
Computing alignments...  [38.634s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.43s]
Computing alignments...  [38.208s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.118s]
Computing alignments...  [38.554s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.466s]
Computing alignments...  [38.89s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0s]
Sorting trace points...  [1.461s]
Computing alignments...  [38.347s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
 [627.417s]
Deallocating reference...  [0.07s]
Loading reference sequences...  [30.925s]
Masking reference...  [30.858s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.7s]
Allocating buffers...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.457s]
Building query seed array...  [2.369s]
Computing hash join...  [5.391s]
Masking low complexity seeds...  [0.271s]
Searching alignments...  [89.154s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.471s]
Building query seed array...  [2.776s]
Computing hash join...  [5.383s]
Masking low complexity seeds...  [0.288s]
Searching alignments...  [57.766s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.449s]
Building query seed array...  [2.955s]
Computing hash join...  [5.308s]
Masking low complexity seeds...  [0.28s]
Searching alignments...  [50.932s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.029s]
Building query seed array...  [2.384s]
Computing hash join...  [5.308s]
Masking low complexity seeds...  [0.277s]
Searching alignments...  [45.16s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.635s]
Building query seed array...  [2.146s]
Computing hash join...  [5.12s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [48.926s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.497s]
Building query seed array...  [2.475s]
Computing hash join...  [5.037s]
Masking low complexity seeds...  [0.269s]
Searching alignments...  [37.589s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.298s]
Building query seed array...  [2.621s]
Computing hash join...  [5.05s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [40.85s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.06s]
Building query seed array...  [2.112s]
Computing hash join...  [5.114s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [34.51s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.757s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.197s]
Sorting trace points...  [1.437s]
Computing alignments...  [35.979s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.04s]
Computing alignments...  [36.298s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.397s]
Computing alignments...  [36.197s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.368s]
Computing alignments...  [36.072s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.109s]
Computing alignments...  [35.686s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.376s]
Computing alignments...  [35.653s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.368s]
Computing alignments...  [35.797s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.225s]
Computing alignments...  [35.671s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.407s]
Computing alignments...  [37.553s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.34s]
Computing alignments...  [38.311s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.448s]
Computing alignments...  [38.349s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.409s]
Computing alignments...  [38.328s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.343s]
Computing alignments...  [38.004s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.331s]
Computing alignments...  [38.308s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.205s]
Computing alignments...  [38.51s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0s]
Sorting trace points...  [1.434s]
Computing alignments...  [38.075s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [622.415s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.588s]
Masking reference...  [30.901s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.704s]
Allocating buffers...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.157s]
Building query seed array...  [2.434s]
Computing hash join...  [5.315s]
Masking low complexity seeds...  [0.279s]
Searching alignments...  [93.903s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.242s]
Building query seed array...  [2.746s]
Computing hash join...  [5.323s]
Masking low complexity seeds...  [0.274s]
Searching alignments...  [60.165s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.31s]
Building query seed array...  [2.908s]
Computing hash join...  [5.289s]
Masking low complexity seeds...  [0.271s]
Searching alignments...  [51.799s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.177s]
Building query seed array...  [2.377s]
Computing hash join...  [5.243s]
Masking low complexity seeds...  [0.273s]
Searching alignments...  [45.82s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.263s]
Building query seed array...  [2.211s]
Computing hash join...  [5.103s]
Masking low complexity seeds...  [0.265s]
Searching alignments...  [50.727s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.137s]
Building query seed array...  [2.423s]
Computing hash join...  [5.178s]
Masking low complexity seeds...  [0.266s]
Searching alignments...  [37.627s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.571s]
Building query seed array...  [2.632s]
Computing hash join...  [5.129s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [43.032s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.054s]
Building query seed array...  [2.186s]
Computing hash join...  [5.051s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [37.766s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.141s]
Clearing query masking...  [1.817s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.208s]
Sorting trace points...  [1.408s]
Computing alignments...  [36.562s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.84s]
Sorting trace points...  [1.287s]
Computing alignments...  [36.951s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.088s]
Sorting trace points...  [1.33s]
Computing alignments...  [36.728s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.27s]
Computing alignments...  [36.465s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.341s]
Computing alignments...  [36.115s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.357s]
Computing alignments...  [36.13s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.281s]
Computing alignments...  [36.196s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.097s]
Sorting trace points...  [1.433s]
Computing alignments...  [36.044s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.23s]
Computing alignments...  [37.951s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.148s]
Computing alignments...  [38.738s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.152s]
Computing alignments...  [38.829s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.522s]
Computing alignments...  [38.739s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.038s]
Sorting trace points...  [1.505s]
Computing alignments...  [38.285s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.534s]
Computing alignments...  [38.719s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.478s]
Computing alignments...  [39.012s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0s]
Sorting trace points...  [1.268s]
Computing alignments...  [38.519s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
 [630.729s]
Deallocating reference...  [0.057s]
Loading reference sequences...  [29.754s]
Masking reference...  [32.151s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.508s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.091s]
Building query seed array...  [2.411s]
Computing hash join...  [5.427s]
Masking low complexity seeds...  [0.273s]
Searching alignments...  [90.614s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.643s]
Building query seed array...  [2.793s]
Computing hash join...  [5.329s]
Masking low complexity seeds...  [0.267s]
Searching alignments...  [58.447s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.598s]
Building query seed array...  [2.841s]
Computing hash join...  [5.405s]
Masking low complexity seeds...  [0.273s]
Searching alignments...  [52.744s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.126s]
Building query seed array...  [2.352s]
Computing hash join...  [5.34s]
Masking low complexity seeds...  [0.272s]
Searching alignments...  [45.173s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.305s]
Building query seed array...  [2.124s]
Computing hash join...  [5.188s]
Masking low complexity seeds...  [0.277s]
Searching alignments...  [50.059s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.969s]
Building query seed array...  [2.494s]
Computing hash join...  [5.059s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [37.287s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.274s]
Building query seed array...  [2.645s]
Computing hash join...  [5.144s]
Masking low complexity seeds...  [0.269s]
Searching alignments...  [42.631s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.429s]
Building query seed array...  [2.145s]
Computing hash join...  [5.094s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [35.346s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.129s]
Clearing query masking...  [1.817s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.121s]
Sorting trace points...  [1.525s]
Computing alignments...  [36.366s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.38s]
Computing alignments...  [36.68s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.394s]
Computing alignments...  [36.612s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.264s]
Computing alignments...  [36.34s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.353s]
Computing alignments...  [35.921s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.311s]
Computing alignments...  [35.925s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.024s]
Computing alignments...  [36.072s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.377s]
Computing alignments...  [35.866s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.001s]
Sorting trace points...  [2.072s]
Computing alignments...  [37.838s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.455s]
Computing alignments...  [38.67s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.451s]
Computing alignments...  [38.762s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.535s]
Computing alignments...  [38.659s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.528s]
Computing alignments...  [38.352s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.475s]
Computing alignments...  [38.643s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.507s]
Computing alignments...  [38.919s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
Sorting trace points...  [1.45s]
Computing alignments...  [38.495s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [629.533s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [29.625s]
Masking reference...  [32.07s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.058s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [9.951s]
Building query seed array...  [2.439s]
Computing hash join...  [5.331s]
Masking low complexity seeds...  [0.279s]
Searching alignments...  [91.312s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.795s]
Building query seed array...  [2.806s]
Computing hash join...  [5.303s]
Masking low complexity seeds...  [0.273s]
Searching alignments...  [56.597s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.97s]
Building query seed array...  [3.002s]
Computing hash join...  [5.353s]
Masking low complexity seeds...  [0.276s]
Searching alignments...  [53.183s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.334s]
Building query seed array...  [2.365s]
Computing hash join...  [5.323s]
Masking low complexity seeds...  [0.277s]
Searching alignments...  [46.937s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.769s]
Building query seed array...  [2.085s]
Computing hash join...  [5.071s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [51.507s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.871s]
Building query seed array...  [2.538s]
Computing hash join...  [5.056s]
Masking low complexity seeds...  [0.259s]
Searching alignments...  [38.378s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.162s]
Building query seed array...  [2.655s]
Computing hash join...  [5.177s]
Masking low complexity seeds...  [0.256s]
Searching alignments...  [42.658s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.1s]
Building query seed array...  [2.1s]
Computing hash join...  [5.015s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [35.665s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.128s]
Clearing query masking...  [1.946s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.098s]
Sorting trace points...  [1.457s]
Computing alignments...  [36.362s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.281s]
Computing alignments...  [36.685s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.275s]
Computing alignments...  [36.514s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.398s]
Computing alignments...  [36.34s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.362s]
Computing alignments...  [35.953s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.12s]
Computing alignments...  [35.887s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.241s]
Computing alignments...  [36.121s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.061s]
Sorting trace points...  [0.972s]
Computing alignments...  [35.858s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.416s]
Computing alignments...  [37.701s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.494s]
Computing alignments...  [38.599s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.48s]
Computing alignments...  [38.678s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.333s]
Computing alignments...  [38.716s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.088s]
Sorting trace points...  [1.532s]
Computing alignments...  [38.393s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.098s]
Computing alignments...  [38.68s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.14s]
Computing alignments...  [38.838s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0s]
Sorting trace points...  [1.446s]
Computing alignments...  [38.486s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [627.297s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [32.597s]
Masking reference...  [31.541s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [31.612s]
Allocating buffers...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.4s]
Building query seed array...  [2.43s]
Computing hash join...  [5.393s]
Masking low complexity seeds...  [0.273s]
Searching alignments...  [93.664s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.126s]
Building query seed array...  [2.758s]
Computing hash join...  [5.34s]
Masking low complexity seeds...  [0.27s]
Searching alignments...  [58.599s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.407s]
Building query seed array...  [2.95s]
Computing hash join...  [5.324s]
Masking low complexity seeds...  [0.271s]
Searching alignments...  [51.723s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.992s]
Building query seed array...  [2.337s]
Computing hash join...  [5.291s]
Masking low complexity seeds...  [0.273s]
Searching alignments...  [44.967s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.078s]
Building query seed array...  [2.104s]
Computing hash join...  [5.092s]
Masking low complexity seeds...  [0.266s]
Searching alignments...  [51.064s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.26s]
Building query seed array...  [2.484s]
Computing hash join...  [5.232s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [37.994s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.244s]
Building query seed array...  [2.63s]
Computing hash join...  [5.07s]
Masking low complexity seeds...  [0.265s]
Searching alignments...  [43.229s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.943s]
Building query seed array...  [2.155s]
Computing hash join...  [5.096s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [35.696s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.131s]
Clearing query masking...  [1.882s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.499s]
Sorting trace points...  [1.25s]
Computing alignments...  [36.317s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.437s]
Computing alignments...  [36.828s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.099s]
Sorting trace points...  [1.335s]
Computing alignments...  [36.736s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.343s]
Computing alignments...  [36.506s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.383s]
Computing alignments...  [36.107s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.187s]
Computing alignments...  [35.962s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.959s]
Sorting trace points...  [1.379s]
Computing alignments...  [36.156s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.311s]
Computing alignments...  [36.033s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.354s]
Computing alignments...  [37.945s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.096s]
Sorting trace points...  [1.104s]
Computing alignments...  [38.802s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.379s]
Computing alignments...  [38.779s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.345s]
Computing alignments...  [38.775s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.129s]
Computing alignments...  [38.401s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.425s]
Computing alignments...  [38.699s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.412s]
Computing alignments...  [38.823s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0s]
Sorting trace points...  [1.518s]
Computing alignments...  [38.491s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [630.443s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.96s]
Masking reference...  [31.963s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.483s]
Allocating buffers...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.307s]
Building query seed array...  [2.387s]
Computing hash join...  [5.358s]
Masking low complexity seeds...  [0.276s]
Searching alignments...  [90.415s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.886s]
Building query seed array...  [2.753s]
Computing hash join...  [5.319s]
Masking low complexity seeds...  [0.272s]
Searching alignments...  [58.128s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [12.838s]
Building query seed array...  [2.97s]
Computing hash join...  [5.317s]
Masking low complexity seeds...  [0.272s]
Searching alignments...  [51.026s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.279s]
Building query seed array...  [2.381s]
Computing hash join...  [5.282s]
Masking low complexity seeds...  [0.277s]
Searching alignments...  [45.826s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.974s]
Building query seed array...  [2.162s]
Computing hash join...  [5.116s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [48.646s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.475s]
Building query seed array...  [2.58s]
Computing hash join...  [5.877s]
Masking low complexity seeds...  [0.289s]
Searching alignments...  [36.847s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.12s]
Building query seed array...  [2.688s]
Computing hash join...  [5.119s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [40.942s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.947s]
Building query seed array...  [2.196s]
Computing hash join...  [5.103s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [35.592s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.131s]
Clearing query masking...  [1.832s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.142s]
Sorting trace points...  [1.397s]
Computing alignments...  [36.472s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.397s]
Computing alignments...  [36.614s]
Deallocating buffers...  [0.024s]
Loading trace points...  [1.021s]
Sorting trace points...  [1.111s]
Computing alignments...  [36.86s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.002s]
Sorting trace points...  [1.407s]
Computing alignments...  [36.295s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.091s]
Sorting trace points...  [1.365s]
Computing alignments...  [35.953s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.365s]
Computing alignments...  [36.012s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.384s]
Computing alignments...  [36.016s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.352s]
Computing alignments...  [35.848s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.096s]
Sorting trace points...  [1.405s]
Computing alignments...  [37.664s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.445s]
Computing alignments...  [38.611s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.472s]
Computing alignments...  [38.635s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.04s]
Sorting trace points...  [1.358s]
Computing alignments...  [38.48s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.531s]
Computing alignments...  [38.268s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.481s]
Computing alignments...  [38.543s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.401s]
Computing alignments...  [39.342s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0s]
Sorting trace points...  [1.466s]
Computing alignments...  [38.416s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [629.687s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [32.032s]
Masking reference...  [31.549s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.281s]
Allocating buffers...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.46s]
Building query seed array...  [2.375s]
Computing hash join...  [5.332s]
Masking low complexity seeds...  [0.266s]
Searching alignments...  [89.651s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.807s]
Building query seed array...  [2.754s]
Computing hash join...  [5.344s]
Masking low complexity seeds...  [0.279s]
Searching alignments...  [58.739s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.792s]
Building query seed array...  [2.854s]
Computing hash join...  [5.379s]
Masking low complexity seeds...  [0.274s]
Searching alignments...  [52.116s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.445s]
Building query seed array...  [2.356s]
Computing hash join...  [5.264s]
Masking low complexity seeds...  [0.274s]
Searching alignments...  [45.797s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.191s]
Building query seed array...  [2.208s]
Computing hash join...  [5.093s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [50.283s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.468s]
Building query seed array...  [2.492s]
Computing hash join...  [5.082s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [37.488s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.739s]
Building query seed array...  [2.668s]
Computing hash join...  [5.084s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [43.325s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.055s]
Building query seed array...  [2.163s]
Computing hash join...  [5.04s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [37.119s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.129s]
Clearing query masking...  [1.848s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.285s]
Sorting trace points...  [1.429s]
Computing alignments...  [36.304s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.368s]
Computing alignments...  [36.594s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.407s]
Computing alignments...  [36.455s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.376s]
Computing alignments...  [36.242s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.416s]
Computing alignments...  [35.969s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.027s]
Computing alignments...  [35.956s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.382s]
Computing alignments...  [36.052s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.361s]
Computing alignments...  [35.89s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.096s]
Sorting trace points...  [1.371s]
Computing alignments...  [37.678s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.146s]
Computing alignments...  [38.674s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.039s]
Sorting trace points...  [1.114s]
Computing alignments...  [38.716s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.327s]
Computing alignments...  [38.668s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.441s]
Computing alignments...  [38.324s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.116s]
Computing alignments...  [38.709s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.539s]
Computing alignments...  [38.92s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
Sorting trace points...  [1.472s]
Computing alignments...  [38.396s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
 [627.17s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [31.688s]
Masking reference...  [32.06s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.552s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.408s]
Building query seed array...  [2.421s]
Computing hash join...  [5.413s]
Masking low complexity seeds...  [0.265s]
Searching alignments...  [91.902s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.526s]
Building query seed array...  [2.737s]
Computing hash join...  [5.309s]
Masking low complexity seeds...  [0.267s]
Searching alignments...  [58.984s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.185s]
Building query seed array...  [2.952s]
Computing hash join...  [5.294s]
Masking low complexity seeds...  [0.27s]
Searching alignments...  [51.917s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.888s]
Building query seed array...  [2.394s]
Computing hash join...  [5.333s]
Masking low complexity seeds...  [0.274s]
Searching alignments...  [46.674s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.049s]
Building query seed array...  [2.189s]
Computing hash join...  [5.125s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [50.876s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.394s]
Building query seed array...  [2.528s]
Computing hash join...  [5.069s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [37.323s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.948s]
Building query seed array...  [2.605s]
Computing hash join...  [5.092s]
Masking low complexity seeds...  [0.283s]
Searching alignments...  [43.192s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.93s]
Building query seed array...  [2.137s]
Computing hash join...  [5.078s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [35.545s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.758s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.043s]
Sorting trace points...  [1.5s]
Computing alignments...  [36.503s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.107s]
Sorting trace points...  [1.435s]
Computing alignments...  [36.657s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.266s]
Computing alignments...  [36.992s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.456s]
Computing alignments...  [36.334s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.344s]
Computing alignments...  [35.891s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.035s]
Computing alignments...  [35.832s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.093s]
Sorting trace points...  [1.098s]
Computing alignments...  [36.128s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.326s]
Computing alignments...  [35.893s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.451s]
Sorting trace points...  [1.324s]
Computing alignments...  [37.661s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.091s]
Sorting trace points...  [1.485s]
Computing alignments...  [38.584s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.455s]
Computing alignments...  [38.675s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.085s]
Sorting trace points...  [1.514s]
Computing alignments...  [38.573s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.432s]
Computing alignments...  [38.361s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.336s]
Computing alignments...  [38.597s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.405s]
Sorting trace points...  [1.538s]
Computing alignments...  [39.277s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
Sorting trace points...  [1.495s]
Computing alignments...  [38.418s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [629.536s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [23.767s]
Masking reference...  [24.994s]
Initializing dictionary...  [0.063s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [26.437s]
Allocating buffers...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.326s]
Building query seed array...  [2.348s]
Computing hash join...  [4.53s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [72.758s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [10.217s]
Building query seed array...  [2.78s]
Computing hash join...  [4.511s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [47.801s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [10.624s]
Building query seed array...  [2.946s]
Computing hash join...  [4.491s]
Masking low complexity seeds...  [0.266s]
Searching alignments...  [43.939s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [8.402s]
Building query seed array...  [2.406s]
Computing hash join...  [4.468s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [36.903s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [8.327s]
Building query seed array...  [2.23s]
Computing hash join...  [4.209s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [41.001s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [9.918s]
Building query seed array...  [2.584s]
Computing hash join...  [4.305s]
Masking low complexity seeds...  [0.256s]
Searching alignments...  [30.666s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [11.062s]
Building query seed array...  [2.703s]
Computing hash join...  [4.279s]
Masking low complexity seeds...  [0.256s]
Searching alignments...  [33.486s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [8.23s]
Building query seed array...  [2.137s]
Computing hash join...  [4.305s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [30.424s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.108s]
Clearing query masking...  [1.845s]
Opening temporary output file...  [0.027s]
Computing alignments... Loading trace points...  [6.016s]
Sorting trace points...  [1.183s]
Computing alignments...  [29.054s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.047s]
Sorting trace points...  [0.928s]
Computing alignments...  [29.294s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.048s]
Computing alignments...  [29.119s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.105s]
Computing alignments...  [28.974s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.076s]
Computing alignments...  [28.64s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.078s]
Sorting trace points...  [0.82s]
Computing alignments...  [28.609s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.132s]
Computing alignments...  [28.728s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.093s]
Computing alignments...  [28.612s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.198s]
Computing alignments...  [30.057s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.142s]
Computing alignments...  [30.77s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.066s]
Sorting trace points...  [0.991s]
Computing alignments...  [30.832s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.236s]
Computing alignments...  [30.707s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.167s]
Computing alignments...  [30.469s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.219s]
Computing alignments...  [30.773s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.13s]
Computing alignments...  [30.968s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
Sorting trace points...  [1.205s]
Computing alignments...  [30.503s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
 [500.966s]
Deallocating reference...  [0.049s]
Loading reference sequences...  [0.073s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [2281.52s]
 [2281.52s]
Deallocating queries...  [0.059s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [4.343s]
 [5.444s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 20519.8s
Reported 2940800368 pairwise alignments, 2940800368 HSPs.
15721007 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E12_R2.fastp-trim.20230215.fq.gz complete: E12_R2.blastx.meganized.daa

Now MEGANizing E12_R2.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: E12_R2.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 100% (248.3s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.2s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (5,518.7s)
Total reads:       15,721,007
With hits:          15,721,007 
Alignments:      2,935,292,957
Assig. Taxonomy:    14,711,321
Assig. SEED:           114,702
Assig. EGGNOG:          50,496
Assig. GTDB:           442,962
Assig. EC:           2,602,809
Assig. INTERPRO2GO:  1,407,357
MinSupport set to: 7860
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.5s)
Min-supp. changes:       4,410
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (13.7s)
Min-supp. changes:       3,632
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (60.4s)
Binning reads Syncing
100% (0.4s)
Class. Taxonomy:            78
Class. SEED:               476
Class. EGGNOG:           1,717
Class. GTDB:                19
Class. EC:               2,347
Class. INTERPRO2GO:      8,169
Total time:  5,851s
Peak memory: 29.8 of 195.3G
MEGANization of E12_R2.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E13_R1.fastp-trim.20230215.fq.gz...
b18f7d4be7507f97f71f8e274cfa6810  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E13_R1.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E13_R1.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.341s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.724s]
Opening the output file...  [0s]
Loading query sequences...  [76.108s]
Masking queries...  [19.261s]
Algorithm: Double-indexed
Building query histograms...  [19.84s]
Loading reference sequences...  [29.37s]
Masking reference...  [32.096s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [31.661s]
Allocating buffers...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.431s]
Building query seed array...  [2.078s]
Computing hash join...  [5.182s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [82.698s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.613s]
Building query seed array...  [2.405s]
Computing hash join...  [5.181s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [50.611s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.165s]
Building query seed array...  [2.548s]
Computing hash join...  [5.053s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [45.364s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.952s]
Building query seed array...  [2.133s]
Computing hash join...  [5.1s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [39.68s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.905s]
Building query seed array...  [1.889s]
Computing hash join...  [4.935s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [41.347s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.332s]
Building query seed array...  [2.169s]
Computing hash join...  [4.953s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [32.545s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.277s]
Building query seed array...  [2.297s]
Computing hash join...  [4.918s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [35.07s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.143s]
Building query seed array...  [1.933s]
Computing hash join...  [4.892s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [30.837s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.611s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.507s]
Sorting trace points...  [1.286s]
Computing alignments...  [32.622s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.159s]
Computing alignments...  [32.777s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.253s]
Computing alignments...  [32.592s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.181s]
Computing alignments...  [33.05s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.258s]
Computing alignments...  [33.041s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.092s]
Sorting trace points...  [1.247s]
Computing alignments...  [33.26s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.299s]
Computing alignments...  [33.346s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.223s]
Computing alignments...  [32.724s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.001s]
Sorting trace points...  [0.92s]
Computing alignments...  [33.229s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.082s]
Computing alignments...  [33.78s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.332s]
Computing alignments...  [33.807s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.224s]
Sorting trace points...  [1.128s]
Computing alignments...  [33.944s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.016s]
Computing alignments...  [33.935s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.09s]
Sorting trace points...  [0.98s]
Computing alignments...  [34.003s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.114s]
Sorting trace points...  [1.294s]
Computing alignments...  [34.026s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.259s]
Computing alignments...  [33.597s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
 [560.597s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [31.012s]
Masking reference...  [31.233s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.179s]
Allocating buffers...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.184s]
Building query seed array...  [2.122s]
Computing hash join...  [5.139s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [81.881s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.393s]
Building query seed array...  [2.414s]
Computing hash join...  [5.071s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [52.663s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.069s]
Building query seed array...  [2.566s]
Computing hash join...  [5.096s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [44.461s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.844s]
Building query seed array...  [2.043s]
Computing hash join...  [5.111s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [41.126s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.367s]
Building query seed array...  [1.91s]
Computing hash join...  [4.899s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [40.705s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.565s]
Building query seed array...  [2.186s]
Computing hash join...  [4.891s]
Masking low complexity seeds...  [0.199s]
Searching alignments...  [33.999s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.411s]
Building query seed array...  [2.369s]
Computing hash join...  [4.827s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [34.501s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.707s]
Building query seed array...  [1.904s]
Computing hash join...  [4.876s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [30.551s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.134s]
Clearing query masking...  [1.606s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.597s]
Sorting trace points...  [1.312s]
Computing alignments...  [32.315s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.059s]
Sorting trace points...  [0.934s]
Computing alignments...  [32.617s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.034s]
Computing alignments...  [32.461s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.25s]
Computing alignments...  [32.869s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.003s]
Computing alignments...  [32.777s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.276s]
Computing alignments...  [32.989s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.221s]
Computing alignments...  [33.158s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.271s]
Computing alignments...  [32.567s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.084s]
Sorting trace points...  [1.272s]
Computing alignments...  [32.923s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.305s]
Computing alignments...  [33.602s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.276s]
Computing alignments...  [33.538s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.299s]
Computing alignments...  [33.754s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.253s]
Sorting trace points...  [1.319s]
Computing alignments...  [33.811s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.114s]
Computing alignments...  [33.719s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.282s]
Computing alignments...  [33.856s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.151s]
Computing alignments...  [33.57s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [557.882s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [30.176s]
Masking reference...  [32.11s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.039s]
Allocating buffers...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.502s]
Building query seed array...  [2.15s]
Computing hash join...  [5.051s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [83.486s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.353s]
Building query seed array...  [2.354s]
Computing hash join...  [5.066s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [52.059s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.438s]
Building query seed array...  [2.645s]
Computing hash join...  [5.033s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [44.704s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.036s]
Building query seed array...  [2.142s]
Computing hash join...  [5.056s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [39.572s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.887s]
Building query seed array...  [1.869s]
Computing hash join...  [4.866s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [40.567s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.014s]
Building query seed array...  [2.269s]
Computing hash join...  [4.856s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [32.783s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.906s]
Building query seed array...  [2.361s]
Computing hash join...  [4.928s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [35.31s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.998s]
Building query seed array...  [1.942s]
Computing hash join...  [4.83s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [31.582s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.129s]
Clearing query masking...  [1.529s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.475s]
Sorting trace points...  [1.335s]
Computing alignments...  [32.562s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.248s]
Computing alignments...  [32.746s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.23s]
Computing alignments...  [32.593s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.238s]
Computing alignments...  [33.03s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.252s]
Computing alignments...  [32.949s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.274s]
Computing alignments...  [33.153s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.21s]
Computing alignments...  [33.31s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.003s]
Sorting trace points...  [1.272s]
Computing alignments...  [32.651s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.266s]
Computing alignments...  [33.018s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.307s]
Computing alignments...  [33.648s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.043s]
Sorting trace points...  [0.986s]
Computing alignments...  [33.591s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.02s]
Computing alignments...  [33.808s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.001s]
Computing alignments...  [33.86s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.164s]
Computing alignments...  [33.862s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.021s]
Computing alignments...  [33.886s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [0.995s]
Computing alignments...  [33.622s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [558.68s]
Deallocating reference...  [0.064s]
Loading reference sequences...  [29.625s]
Masking reference...  [30.837s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.036s]
Allocating buffers...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.032s]
Building query seed array...  [2.186s]
Computing hash join...  [5.152s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [81.799s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.426s]
Building query seed array...  [2.437s]
Computing hash join...  [5.113s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [51.002s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.2s]
Building query seed array...  [2.68s]
Computing hash join...  [4.993s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [46.431s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.982s]
Building query seed array...  [2.075s]
Computing hash join...  [5.165s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [40.337s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.015s]
Building query seed array...  [1.907s]
Computing hash join...  [4.942s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [40.661s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.7s]
Building query seed array...  [2.237s]
Computing hash join...  [5.097s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [33.498s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.789s]
Building query seed array...  [2.313s]
Computing hash join...  [4.9s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [34.478s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.917s]
Building query seed array...  [1.973s]
Computing hash join...  [4.907s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [30.676s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.132s]
Clearing query masking...  [1.608s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.699s]
Sorting trace points...  [1.312s]
Computing alignments...  [32.538s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.26s]
Computing alignments...  [32.951s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.086s]
Computing alignments...  [32.576s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.075s]
Sorting trace points...  [0.935s]
Computing alignments...  [33.186s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.089s]
Computing alignments...  [33.044s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.092s]
Sorting trace points...  [1.333s]
Computing alignments...  [33.228s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.033s]
Computing alignments...  [33.487s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.001s]
Sorting trace points...  [0.995s]
Computing alignments...  [32.748s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.24s]
Computing alignments...  [33.146s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.262s]
Computing alignments...  [33.693s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.312s]
Computing alignments...  [33.902s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.29s]
Computing alignments...  [33.981s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.246s]
Computing alignments...  [33.978s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.313s]
Computing alignments...  [34.102s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.663s]
Sorting trace points...  [1.325s]
Computing alignments...  [34.089s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.195s]
Computing alignments...  [33.698s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
 [562.02s]
Deallocating reference...  [0.07s]
Loading reference sequences...  [29.606s]
Masking reference...  [30.822s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.601s]
Allocating buffers...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.497s]
Building query seed array...  [2.139s]
Computing hash join...  [5.148s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [81.298s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.165s]
Building query seed array...  [2.508s]
Computing hash join...  [5.164s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [52.579s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.94s]
Building query seed array...  [2.629s]
Computing hash join...  [5.042s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [45.577s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.241s]
Building query seed array...  [2.119s]
Computing hash join...  [5.042s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [39.154s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.916s]
Building query seed array...  [1.888s]
Computing hash join...  [4.821s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [41.381s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.291s]
Building query seed array...  [2.213s]
Computing hash join...  [4.94s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [33.058s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.487s]
Building query seed array...  [2.328s]
Computing hash join...  [4.909s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [35.094s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.962s]
Building query seed array...  [1.9s]
Computing hash join...  [4.883s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [31.732s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.129s]
Clearing query masking...  [1.531s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.971s]
Sorting trace points...  [0.892s]
Computing alignments...  [32.314s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.536s]
Sorting trace points...  [1.23s]
Computing alignments...  [32.595s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.095s]
Sorting trace points...  [1.23s]
Computing alignments...  [32.521s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.082s]
Computing alignments...  [32.917s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.266s]
Computing alignments...  [32.986s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.275s]
Computing alignments...  [33.203s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.228s]
Computing alignments...  [33.396s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.287s]
Computing alignments...  [32.542s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.833s]
Sorting trace points...  [1.246s]
Computing alignments...  [32.974s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.202s]
Computing alignments...  [33.575s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.321s]
Computing alignments...  [33.53s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.038s]
Sorting trace points...  [1.33s]
Computing alignments...  [33.764s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.297s]
Computing alignments...  [33.872s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.289s]
Computing alignments...  [33.953s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.337s]
Computing alignments...  [33.92s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.166s]
Computing alignments...  [33.556s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [560.849s]
Deallocating reference...  [0.073s]
Loading reference sequences...  [29.635s]
Masking reference...  [32.069s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [31.503s]
Allocating buffers...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [9.967s]
Building query seed array...  [2.143s]
Computing hash join...  [5.049s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [78.283s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.712s]
Building query seed array...  [2.427s]
Computing hash join...  [5.108s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [49.726s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.257s]
Building query seed array...  [2.544s]
Computing hash join...  [4.967s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [44.352s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.989s]
Building query seed array...  [2.058s]
Computing hash join...  [4.994s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [39.893s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.918s]
Building query seed array...  [1.938s]
Computing hash join...  [4.922s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [38.947s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.238s]
Building query seed array...  [2.242s]
Computing hash join...  [4.805s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [32.205s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.382s]
Building query seed array...  [2.304s]
Computing hash join...  [4.768s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [35.451s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.254s]
Building query seed array...  [1.948s]
Computing hash join...  [4.882s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [29.99s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.136s]
Clearing query masking...  [1.607s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.482s]
Sorting trace points...  [1.305s]
Computing alignments...  [32.235s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.047s]
Computing alignments...  [32.33s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.262s]
Computing alignments...  [32.204s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.302s]
Computing alignments...  [32.622s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.264s]
Computing alignments...  [32.573s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.135s]
Computing alignments...  [32.868s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.275s]
Computing alignments...  [33s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.047s]
Computing alignments...  [32.314s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.084s]
Sorting trace points...  [1.245s]
Computing alignments...  [32.933s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.066s]
Sorting trace points...  [0.989s]
Computing alignments...  [33.576s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.216s]
Computing alignments...  [33.533s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.281s]
Computing alignments...  [33.602s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.304s]
Computing alignments...  [33.631s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.26s]
Computing alignments...  [33.692s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.27s]
Computing alignments...  [33.794s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.28s]
Computing alignments...  [33.224s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
 [555.352s]
Deallocating reference...  [0.064s]
Loading reference sequences...  [29.402s]
Masking reference...  [32.015s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.344s]
Allocating buffers...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.217s]
Building query seed array...  [2.142s]
Computing hash join...  [5.037s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [82.142s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.209s]
Building query seed array...  [2.432s]
Computing hash join...  [5.046s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [52.002s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.284s]
Building query seed array...  [2.602s]
Computing hash join...  [5.028s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [45.51s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.928s]
Building query seed array...  [2.069s]
Computing hash join...  [4.993s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [40.802s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.941s]
Building query seed array...  [1.951s]
Computing hash join...  [4.886s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [42.421s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.628s]
Building query seed array...  [2.232s]
Computing hash join...  [4.851s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [32.365s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.287s]
Building query seed array...  [2.374s]
Computing hash join...  [4.8s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [35.58s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.154s]
Building query seed array...  [1.94s]
Computing hash join...  [4.84s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [30.987s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.127s]
Clearing query masking...  [1.602s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.528s]
Sorting trace points...  [1.309s]
Computing alignments...  [32.555s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.045s]
Computing alignments...  [32.651s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.255s]
Computing alignments...  [32.42s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.261s]
Computing alignments...  [32.859s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.248s]
Computing alignments...  [32.817s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.237s]
Computing alignments...  [33.113s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.196s]
Computing alignments...  [33.28s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.254s]
Computing alignments...  [32.583s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
Sorting trace points...  [1.054s]
Computing alignments...  [33.015s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.336s]
Computing alignments...  [33.52s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.042s]
Sorting trace points...  [1.133s]
Computing alignments...  [33.659s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.304s]
Computing alignments...  [33.791s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.245s]
Computing alignments...  [33.777s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.303s]
Computing alignments...  [33.907s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.285s]
Computing alignments...  [33.928s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.114s]
Computing alignments...  [33.53s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [558.644s]
Deallocating reference...  [0.069s]
Loading reference sequences...  [29.509s]
Masking reference...  [30.833s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.333s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.288s]
Building query seed array...  [2.139s]
Computing hash join...  [5.086s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [79.41s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.662s]
Building query seed array...  [2.403s]
Computing hash join...  [5.08s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [53.148s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.523s]
Building query seed array...  [2.663s]
Computing hash join...  [5.033s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [44.735s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.01s]
Building query seed array...  [2.058s]
Computing hash join...  [5.033s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [39.25s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.355s]
Building query seed array...  [1.904s]
Computing hash join...  [4.818s]
Masking low complexity seeds...  [0.198s]
Searching alignments...  [40.615s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.459s]
Building query seed array...  [2.164s]
Computing hash join...  [4.948s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [33.084s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.365s]
Building query seed array...  [2.334s]
Computing hash join...  [4.819s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [35.452s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.618s]
Building query seed array...  [1.917s]
Computing hash join...  [4.817s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [32.207s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.134s]
Clearing query masking...  [1.632s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.785s]
Sorting trace points...  [1.151s]
Computing alignments...  [32.519s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.2s]
Computing alignments...  [32.547s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.001s]
Computing alignments...  [32.395s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.052s]
Computing alignments...  [32.771s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.184s]
Computing alignments...  [32.827s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.243s]
Computing alignments...  [33.036s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.216s]
Computing alignments...  [33.243s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.002s]
Sorting trace points...  [1.267s]
Computing alignments...  [32.529s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.241s]
Computing alignments...  [33.029s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.305s]
Computing alignments...  [33.528s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.167s]
Computing alignments...  [33.6s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.036s]
Sorting trace points...  [1.069s]
Computing alignments...  [33.725s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.288s]
Computing alignments...  [33.828s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.148s]
Computing alignments...  [33.796s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.335s]
Computing alignments...  [33.811s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.283s]
Computing alignments...  [33.524s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [557.802s]
Deallocating reference...  [0.069s]
Loading reference sequences...  [29.705s]
Masking reference...  [30.833s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.715s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.233s]
Building query seed array...  [2.149s]
Computing hash join...  [5.031s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [81.405s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.55s]
Building query seed array...  [2.454s]
Computing hash join...  [5.099s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [50.328s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.834s]
Building query seed array...  [2.557s]
Computing hash join...  [4.978s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [46.405s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.295s]
Building query seed array...  [2.072s]
Computing hash join...  [5.127s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [41.047s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.147s]
Building query seed array...  [1.88s]
Computing hash join...  [4.895s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [39.826s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.413s]
Building query seed array...  [2.191s]
Computing hash join...  [4.84s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [32.549s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.709s]
Building query seed array...  [2.37s]
Computing hash join...  [4.932s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [35.424s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.108s]
Building query seed array...  [1.946s]
Computing hash join...  [4.822s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [30.65s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.128s]
Clearing query masking...  [1.613s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.47s]
Sorting trace points...  [1.306s]
Computing alignments...  [32.563s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.257s]
Computing alignments...  [32.711s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.263s]
Computing alignments...  [32.487s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.263s]
Computing alignments...  [33.103s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.278s]
Computing alignments...  [32.894s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.249s]
Computing alignments...  [33.18s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.095s]
Sorting trace points...  [1.152s]
Computing alignments...  [33.446s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.301s]
Computing alignments...  [32.739s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.121s]
Computing alignments...  [33.28s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.28s]
Computing alignments...  [33.709s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.049s]
Sorting trace points...  [0.996s]
Computing alignments...  [33.799s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.26s]
Computing alignments...  [33.958s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.165s]
Computing alignments...  [33.97s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.04s]
Sorting trace points...  [1.238s]
Computing alignments...  [34.028s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.135s]
Computing alignments...  [33.985s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.317s]
Computing alignments...  [33.627s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [560.839s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [29.799s]
Masking reference...  [30.825s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [33.38s]
Allocating buffers...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.242s]
Building query seed array...  [2.088s]
Computing hash join...  [5.121s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [81.09s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.71s]
Building query seed array...  [2.496s]
Computing hash join...  [5.137s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [53.021s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.105s]
Building query seed array...  [2.571s]
Computing hash join...  [5.01s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [45.984s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.121s]
Building query seed array...  [2.06s]
Computing hash join...  [5.093s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [40.984s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.351s]
Building query seed array...  [1.883s]
Computing hash join...  [4.964s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [41.964s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.322s]
Building query seed array...  [2.149s]
Computing hash join...  [4.896s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [32.577s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.668s]
Building query seed array...  [2.336s]
Computing hash join...  [4.802s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [36.291s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.027s]
Building query seed array...  [1.969s]
Computing hash join...  [4.778s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [31.122s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.128s]
Clearing query masking...  [1.535s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.489s]
Sorting trace points...  [1.302s]
Computing alignments...  [32.461s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.274s]
Computing alignments...  [32.673s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.087s]
Sorting trace points...  [1.233s]
Computing alignments...  [33.045s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.14s]
Sorting trace points...  [1.278s]
Computing alignments...  [33.013s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.295s]
Computing alignments...  [32.94s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.289s]
Computing alignments...  [33.099s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.022s]
Computing alignments...  [33.388s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.243s]
Computing alignments...  [32.692s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.284s]
Computing alignments...  [33.06s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.195s]
Computing alignments...  [33.597s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.293s]
Computing alignments...  [33.645s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.039s]
Sorting trace points...  [1.282s]
Computing alignments...  [33.846s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.024s]
Computing alignments...  [33.861s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.28s]
Computing alignments...  [33.902s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.295s]
Computing alignments...  [33.957s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.302s]
Computing alignments...  [33.512s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [560.391s]
Deallocating reference...  [0.076s]
Loading reference sequences...  [29.679s]
Masking reference...  [32.058s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.54s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.421s]
Building query seed array...  [2.114s]
Computing hash join...  [5.12s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [79.159s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.501s]
Building query seed array...  [2.464s]
Computing hash join...  [5.284s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [49.997s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.343s]
Building query seed array...  [2.59s]
Computing hash join...  [5.026s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [44.433s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.036s]
Building query seed array...  [2.094s]
Computing hash join...  [5.104s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [39.878s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.636s]
Building query seed array...  [1.906s]
Computing hash join...  [4.965s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [39.445s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.363s]
Building query seed array...  [2.233s]
Computing hash join...  [4.919s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [32.365s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.588s]
Building query seed array...  [2.404s]
Computing hash join...  [4.892s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [34.968s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.875s]
Building query seed array...  [1.943s]
Computing hash join...  [4.893s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [30.586s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.131s]
Clearing query masking...  [1.559s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.35s]
Sorting trace points...  [1.303s]
Computing alignments...  [32.401s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.047s]
Sorting trace points...  [1s]
Computing alignments...  [32.633s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.206s]
Computing alignments...  [32.513s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.159s]
Computing alignments...  [32.971s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.034s]
Computing alignments...  [32.92s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.106s]
Sorting trace points...  [0.96s]
Computing alignments...  [33.162s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.143s]
Computing alignments...  [33.372s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.276s]
Computing alignments...  [32.717s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.102s]
Sorting trace points...  [1.103s]
Computing alignments...  [33.08s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.273s]
Computing alignments...  [33.643s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.261s]
Computing alignments...  [33.631s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.065s]
Sorting trace points...  [0.957s]
Computing alignments...  [33.952s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.047s]
Computing alignments...  [33.922s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.04s]
Computing alignments...  [33.851s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.306s]
Computing alignments...  [33.984s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.247s]
Computing alignments...  [33.631s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
 [558.46s]
Deallocating reference...  [0.07s]
Loading reference sequences...  [29.608s]
Masking reference...  [30.843s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.006s]
Building reference histograms...  [32.215s]
Allocating buffers...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.273s]
Building query seed array...  [2.169s]
Computing hash join...  [5.075s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [81.375s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.538s]
Building query seed array...  [2.466s]
Computing hash join...  [5.049s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [52.2s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.35s]
Building query seed array...  [2.609s]
Computing hash join...  [5.092s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [45.11s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.962s]
Building query seed array...  [2.095s]
Computing hash join...  [4.978s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [40.415s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.209s]
Building query seed array...  [1.915s]
Computing hash join...  [4.86s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [40.73s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.655s]
Building query seed array...  [2.292s]
Computing hash join...  [4.864s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [33.754s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.608s]
Building query seed array...  [2.313s]
Computing hash join...  [4.894s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [36.32s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.03s]
Building query seed array...  [1.908s]
Computing hash join...  [4.87s]
Masking low complexity seeds...  [0.197s]
Searching alignments...  [30.918s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.135s]
Clearing query masking...  [1.626s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.641s]
Sorting trace points...  [1.307s]
Computing alignments...  [32.381s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.3s]
Computing alignments...  [32.626s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.21s]
Computing alignments...  [32.329s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.267s]
Computing alignments...  [32.795s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.247s]
Computing alignments...  [33.11s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.175s]
Computing alignments...  [33.092s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.23s]
Computing alignments...  [33.172s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
Sorting trace points...  [1.259s]
Computing alignments...  [32.522s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.271s]
Computing alignments...  [33.014s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.335s]
Computing alignments...  [33.53s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.173s]
Computing alignments...  [33.541s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.148s]
Computing alignments...  [33.661s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.304s]
Computing alignments...  [33.69s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.297s]
Computing alignments...  [33.89s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.185s]
Computing alignments...  [33.812s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.165s]
Computing alignments...  [33.487s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [558.344s]
Deallocating reference...  [0.069s]
Loading reference sequences...  [29.506s]
Masking reference...  [30.83s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.006s]
Building reference histograms...  [32.293s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [9.989s]
Building query seed array...  [2.081s]
Computing hash join...  [5.106s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [82.582s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.397s]
Building query seed array...  [2.482s]
Computing hash join...  [5.018s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [52.724s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.177s]
Building query seed array...  [2.585s]
Computing hash join...  [5.054s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [44.794s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.064s]
Building query seed array...  [2.052s]
Computing hash join...  [5.005s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [39.451s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.178s]
Building query seed array...  [1.916s]
Computing hash join...  [4.844s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [40.159s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.423s]
Building query seed array...  [2.236s]
Computing hash join...  [4.819s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [32.817s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.329s]
Building query seed array...  [2.287s]
Computing hash join...  [4.892s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [36.171s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.005s]
Building query seed array...  [1.959s]
Computing hash join...  [4.81s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [30.567s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.597s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.34s]
Sorting trace points...  [1.29s]
Computing alignments...  [32.591s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.231s]
Computing alignments...  [32.784s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.281s]
Computing alignments...  [32.514s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.061s]
Sorting trace points...  [0.977s]
Computing alignments...  [32.911s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.224s]
Computing alignments...  [32.835s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.246s]
Computing alignments...  [32.976s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.028s]
Computing alignments...  [33.358s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.26s]
Computing alignments...  [32.599s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.516s]
Sorting trace points...  [1.177s]
Computing alignments...  [33.067s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.217s]
Computing alignments...  [33.631s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.276s]
Computing alignments...  [33.675s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.197s]
Computing alignments...  [33.897s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.073s]
Sorting trace points...  [0.975s]
Computing alignments...  [33.859s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.291s]
Computing alignments...  [33.939s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.296s]
Computing alignments...  [33.772s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [0.982s]
Computing alignments...  [33.558s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [558.926s]
Deallocating reference...  [0.072s]
Loading reference sequences...  [26.643s]
Masking reference...  [25.789s]
Initializing dictionary...  [0.063s]
Initializing temporary storage...  [0.006s]
Building reference histograms...  [26.201s]
Allocating buffers...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.169s]
Building query seed array...  [2.066s]
Computing hash join...  [4.168s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [67.311s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [10.525s]
Building query seed array...  [2.515s]
Computing hash join...  [4.218s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [42.741s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [11.381s]
Building query seed array...  [2.551s]
Computing hash join...  [4.229s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [38.503s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [8.421s]
Building query seed array...  [2.2s]
Computing hash join...  [4.228s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [33.312s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [8.328s]
Building query seed array...  [1.921s]
Computing hash join...  [4.081s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [32.825s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [9.933s]
Building query seed array...  [2.231s]
Computing hash join...  [4.01s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [26.572s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [10.674s]
Building query seed array...  [2.287s]
Computing hash join...  [4.024s]
Masking low complexity seeds...  [0.2s]
Searching alignments...  [29.467s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [8.026s]
Building query seed array...  [1.888s]
Computing hash join...  [4.088s]
Masking low complexity seeds...  [0.196s]
Searching alignments...  [25.102s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.106s]
Clearing query masking...  [1.533s]
Opening temporary output file...  [0.002s]
Computing alignments... Loading trace points...  [10.748s]
Sorting trace points...  [2.13s]
Computing alignments...  [51.767s]
Deallocating buffers...  [0.036s]
Loading trace points...  [0.122s]
Sorting trace points...  [1.611s]
Computing alignments...  [52.108s]
Deallocating buffers...  [0.032s]
Loading trace points...  [0.209s]
Sorting trace points...  [1.724s]
Computing alignments...  [52.556s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.181s]
Sorting trace points...  [1.606s]
Computing alignments...  [52.347s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.14s]
Sorting trace points...  [1.812s]
Computing alignments...  [53.124s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.135s]
Sorting trace points...  [1.746s]
Computing alignments...  [53.825s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.002s]
Sorting trace points...  [1.76s]
Computing alignments...  [53.909s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0s]
Sorting trace points...  [1.83s]
Computing alignments...  [53.52s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0s]
 [449.226s]
Deallocating reference...  [0.052s]
Loading reference sequences...  [0.11s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [1980.35s]
 [1980.35s]
Deallocating queries...  [0.059s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [3.711s]
 [4.775s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 18184.1s
Reported 2549826695 pairwise alignments, 2549826695 HSPs.
13634465 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E13_R1.fastp-trim.20230215.fq.gz complete: E13_R1.blastx.meganized.daa

Now MEGANizing E13_R1.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: E13_R1.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 100% (228.6s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.1s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (4,683.1s)
Total reads:       13,634,465
With hits:          13,634,465 
Alignments:      2,542,269,474
Assig. Taxonomy:    12,787,162
Assig. SEED:           101,148
Assig. EGGNOG:          42,646
Assig. GTDB:           379,078
Assig. EC:           2,194,632
Assig. INTERPRO2GO:  1,177,562
MinSupport set to: 6817
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.3s)
Min-supp. changes:       3,745
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (10.5s)
Min-supp. changes:       2,825
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (44.7s)
Binning reads Syncing
100% (0.4s)
Class. Taxonomy:            71
Class. SEED:               472
Class. EGGNOG:           1,664
Class. GTDB:                17
Class. EC:               2,252
Class. INTERPRO2GO:      7,544
Total time:  4,977s
Peak memory: 31 of 195.3G
MEGANization of E13_R1.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E13_R2.fastp-trim.20230215.fq.gz...
5e0ab8cee682d3b0b72147b62e659e35  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E13_R2.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E13_R2.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.314s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.73s]
Opening the output file...  [0s]
Loading query sequences...  [76.133s]
Masking queries...  [19.122s]
Algorithm: Double-indexed
Building query histograms...  [19.895s]
Loading reference sequences...  [31.372s]
Masking reference...  [32.006s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.956s]
Allocating buffers...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.436s]
Building query seed array...  [2.144s]
Computing hash join...  [5.4s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [81.311s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.302s]
Building query seed array...  [2.406s]
Computing hash join...  [5.185s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [53.054s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.626s]
Building query seed array...  [2.62s]
Computing hash join...  [5.202s]
Masking low complexity seeds...  [0.256s]
Searching alignments...  [46.099s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.874s]
Building query seed array...  [2.1s]
Computing hash join...  [5.212s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [41.479s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.141s]
Building query seed array...  [1.941s]
Computing hash join...  [4.972s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [45.615s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.094s]
Building query seed array...  [2.252s]
Computing hash join...  [5.005s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [34.836s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.335s]
Building query seed array...  [2.4s]
Computing hash join...  [5.022s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [38.566s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.832s]
Building query seed array...  [1.968s]
Computing hash join...  [4.876s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [31.79s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.134s]
Clearing query masking...  [1.636s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.662s]
Sorting trace points...  [1.339s]
Computing alignments...  [33.089s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.032s]
Sorting trace points...  [0.963s]
Computing alignments...  [32.745s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.194s]
Computing alignments...  [33.048s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.059s]
Sorting trace points...  [0.937s]
Computing alignments...  [32.546s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.235s]
Computing alignments...  [32.422s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.169s]
Computing alignments...  [32.199s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.053s]
Sorting trace points...  [0.948s]
Computing alignments...  [32.258s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.037s]
Sorting trace points...  [0.92s]
Computing alignments...  [32.071s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.29s]
Computing alignments...  [33.731s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.374s]
Computing alignments...  [34.588s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.377s]
Computing alignments...  [34.717s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.36s]
Computing alignments...  [34.858s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.768s]
Sorting trace points...  [1.327s]
Computing alignments...  [34.761s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.085s]
Sorting trace points...  [1.361s]
Computing alignments...  [34.884s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.175s]
Computing alignments...  [34.853s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.35s]
Computing alignments...  [34.43s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [565.209s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.685s]
Masking reference...  [30.922s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.809s]
Allocating buffers...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [9.933s]
Building query seed array...  [2.103s]
Computing hash join...  [5.2s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [78.673s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.338s]
Building query seed array...  [2.499s]
Computing hash join...  [5.229s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [51.546s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.59s]
Building query seed array...  [2.674s]
Computing hash join...  [5.139s]
Masking low complexity seeds...  [0.249s]
Searching alignments...  [44.358s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.008s]
Building query seed array...  [2.083s]
Computing hash join...  [5.226s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [39.794s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.274s]
Building query seed array...  [1.893s]
Computing hash join...  [5.091s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [44.571s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.24s]
Building query seed array...  [2.26s]
Computing hash join...  [4.952s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [33.61s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.466s]
Building query seed array...  [2.308s]
Computing hash join...  [4.995s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [36.339s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.102s]
Building query seed array...  [1.912s]
Computing hash join...  [4.979s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [31.09s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.13s]
Clearing query masking...  [1.607s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.573s]
Sorting trace points...  [1.337s]
Computing alignments...  [33.041s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.202s]
Computing alignments...  [33.189s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.039s]
Sorting trace points...  [0.935s]
Computing alignments...  [32.982s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.281s]
Computing alignments...  [32.504s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.259s]
Computing alignments...  [32.4s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.2s]
Computing alignments...  [32.093s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.222s]
Computing alignments...  [32.292s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.085s]
Computing alignments...  [31.932s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.233s]
Computing alignments...  [33.64s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.322s]
Computing alignments...  [34.459s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.028s]
Computing alignments...  [34.548s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.376s]
Computing alignments...  [34.641s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.355s]
Computing alignments...  [34.793s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.327s]
Computing alignments...  [34.802s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.087s]
Sorting trace points...  [1.024s]
Computing alignments...  [34.602s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.245s]
Computing alignments...  [34.317s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
 [563.491s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [29.543s]
Masking reference...  [30.901s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.809s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.437s]
Building query seed array...  [2.133s]
Computing hash join...  [5.233s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [82.145s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.35s]
Building query seed array...  [2.522s]
Computing hash join...  [5.204s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [53.909s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.295s]
Building query seed array...  [2.614s]
Computing hash join...  [5.141s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [46.699s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.183s]
Building query seed array...  [2.101s]
Computing hash join...  [5.345s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [41.075s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.981s]
Building query seed array...  [1.877s]
Computing hash join...  [4.96s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [45.149s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.717s]
Building query seed array...  [2.211s]
Computing hash join...  [5.035s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [33.61s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.541s]
Building query seed array...  [2.298s]
Computing hash join...  [5.001s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [38.774s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.183s]
Building query seed array...  [1.961s]
Computing hash join...  [4.948s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [31.987s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.141s]
Clearing query masking...  [1.656s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.828s]
Sorting trace points...  [1.319s]
Computing alignments...  [32.867s]
Deallocating buffers...  [0.017s]
Loading trace points...  [1.078s]
Sorting trace points...  [0.993s]
Computing alignments...  [32.626s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.07s]
Computing alignments...  [33.506s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.156s]
Computing alignments...  [32.536s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.088s]
Sorting trace points...  [1.212s]
Computing alignments...  [32.185s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.163s]
Sorting trace points...  [1.171s]
Computing alignments...  [32.042s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.255s]
Computing alignments...  [32.245s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.044s]
Sorting trace points...  [0.959s]
Computing alignments...  [31.919s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.311s]
Computing alignments...  [33.684s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.312s]
Computing alignments...  [34.374s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.105s]
Computing alignments...  [34.531s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.328s]
Computing alignments...  [34.564s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.317s]
Computing alignments...  [34.749s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.358s]
Computing alignments...  [34.686s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.33s]
Computing alignments...  [34.725s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.325s]
Computing alignments...  [34.466s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [564.466s]
Deallocating reference...  [0.065s]
Loading reference sequences...  [29.865s]
Masking reference...  [30.993s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.852s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.603s]
Building query seed array...  [2.2s]
Computing hash join...  [5.245s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [81.193s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.416s]
Building query seed array...  [2.467s]
Computing hash join...  [5.201s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [53.063s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.245s]
Building query seed array...  [2.558s]
Computing hash join...  [5.2s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [47.163s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.142s]
Building query seed array...  [2.1s]
Computing hash join...  [5.243s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [41.873s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.952s]
Building query seed array...  [1.875s]
Computing hash join...  [4.991s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [44.641s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.316s]
Building query seed array...  [2.226s]
Computing hash join...  [4.963s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [33.401s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.025s]
Building query seed array...  [2.322s]
Computing hash join...  [5.043s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [38.311s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.147s]
Building query seed array...  [1.874s]
Computing hash join...  [4.963s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [31.244s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.566s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.693s]
Sorting trace points...  [1.302s]
Computing alignments...  [32.805s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.002s]
Sorting trace points...  [0.978s]
Computing alignments...  [32.64s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.033s]
Sorting trace points...  [0.945s]
Computing alignments...  [32.89s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.247s]
Computing alignments...  [32.559s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.254s]
Computing alignments...  [32.288s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.255s]
Computing alignments...  [32.07s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.06s]
Sorting trace points...  [0.909s]
Computing alignments...  [32.233s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.225s]
Computing alignments...  [32.012s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.04s]
Sorting trace points...  [1.006s]
Computing alignments...  [33.672s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.287s]
Computing alignments...  [34.392s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.129s]
Computing alignments...  [34.589s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.121s]
Computing alignments...  [34.694s]
Deallocating buffers...  [0.023s]
Loading trace points...  [1.195s]
Sorting trace points...  [1.32s]
Computing alignments...  [34.599s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.099s]
Sorting trace points...  [1.344s]
Computing alignments...  [34.696s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.042s]
Sorting trace points...  [1.327s]
Computing alignments...  [34.693s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.295s]
Computing alignments...  [34.335s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [563.071s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [30.412s]
Masking reference...  [31.096s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.052s]
Allocating buffers...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.206s]
Building query seed array...  [2.098s]
Computing hash join...  [5.123s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [80.287s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.337s]
Building query seed array...  [2.388s]
Computing hash join...  [5.237s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [51.455s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.203s]
Building query seed array...  [2.64s]
Computing hash join...  [5.35s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [44.991s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.846s]
Building query seed array...  [2.129s]
Computing hash join...  [5.175s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [40.166s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.091s]
Building query seed array...  [1.886s]
Computing hash join...  [4.964s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [43.01s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.225s]
Building query seed array...  [2.238s]
Computing hash join...  [5.051s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [33.593s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.973s]
Building query seed array...  [2.349s]
Computing hash join...  [4.972s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [36.442s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.937s]
Building query seed array...  [1.925s]
Computing hash join...  [5.058s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [30.706s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.141s]
Clearing query masking...  [1.614s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.701s]
Sorting trace points...  [1.335s]
Computing alignments...  [32.587s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.233s]
Computing alignments...  [32.381s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.063s]
Sorting trace points...  [0.985s]
Computing alignments...  [32.715s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.129s]
Computing alignments...  [32.374s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.259s]
Computing alignments...  [32.263s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.23s]
Computing alignments...  [31.869s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.26s]
Computing alignments...  [32.012s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.143s]
Computing alignments...  [31.814s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.268s]
Computing alignments...  [33.526s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.179s]
Computing alignments...  [34.278s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.306s]
Computing alignments...  [34.431s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.332s]
Computing alignments...  [34.506s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.326s]
Computing alignments...  [34.561s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.314s]
Computing alignments...  [34.555s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.338s]
Computing alignments...  [34.657s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.07s]
Computing alignments...  [34.329s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [560.376s]
Deallocating reference...  [0.066s]
Loading reference sequences...  [29.503s]
Masking reference...  [32.218s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.19s]
Allocating buffers...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.308s]
Building query seed array...  [2.123s]
Computing hash join...  [5.211s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [77.848s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.195s]
Building query seed array...  [2.516s]
Computing hash join...  [5.212s]
Masking low complexity seeds...  [0.271s]
Searching alignments...  [51.116s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.704s]
Building query seed array...  [2.673s]
Computing hash join...  [5.151s]
Masking low complexity seeds...  [0.256s]
Searching alignments...  [45.039s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.289s]
Building query seed array...  [2.099s]
Computing hash join...  [5.193s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [39.026s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.995s]
Building query seed array...  [1.862s]
Computing hash join...  [4.967s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [41.944s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.617s]
Building query seed array...  [2.197s]
Computing hash join...  [5.037s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [32.808s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.196s]
Building query seed array...  [2.371s]
Computing hash join...  [4.987s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [35.15s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.665s]
Building query seed array...  [1.935s]
Computing hash join...  [4.968s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [29.897s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.13s]
Clearing query masking...  [1.564s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [7.225s]
Sorting trace points...  [1.329s]
Computing alignments...  [32.291s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.149s]
Computing alignments...  [32.095s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.065s]
Sorting trace points...  [0.981s]
Computing alignments...  [32.471s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.071s]
Sorting trace points...  [0.98s]
Computing alignments...  [31.906s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.292s]
Computing alignments...  [31.826s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.191s]
Computing alignments...  [31.607s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.145s]
Computing alignments...  [31.688s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.215s]
Computing alignments...  [31.614s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.058s]
Sorting trace points...  [0.983s]
Computing alignments...  [33.272s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.332s]
Computing alignments...  [34.011s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.064s]
Computing alignments...  [34.165s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.324s]
Computing alignments...  [34.229s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.136s]
Computing alignments...  [34.232s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.093s]
Sorting trace points...  [1.318s]
Computing alignments...  [34.216s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.639s]
Sorting trace points...  [1.418s]
Computing alignments...  [34.346s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.343s]
Computing alignments...  [33.904s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
 [556.107s]
Deallocating reference...  [0.065s]
Loading reference sequences...  [29.591s]
Masking reference...  [32.066s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [31.687s]
Allocating buffers...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.242s]
Building query seed array...  [2.098s]
Computing hash join...  [5.146s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [81.989s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.355s]
Building query seed array...  [2.446s]
Computing hash join...  [5.271s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [53.951s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [12.946s]
Building query seed array...  [2.635s]
Computing hash join...  [5.077s]
Masking low complexity seeds...  [0.575s]
Searching alignments...  [45.359s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.02s]
Building query seed array...  [2.054s]
Computing hash join...  [5.204s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [39.454s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.313s]
Building query seed array...  [1.893s]
Computing hash join...  [5.01s]
Masking low complexity seeds...  [0.382s]
Searching alignments...  [44.273s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.778s]
Building query seed array...  [2.209s]
Computing hash join...  [5.024s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [33.346s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.168s]
Building query seed array...  [2.381s]
Computing hash join...  [4.886s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [38.615s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.986s]
Building query seed array...  [1.925s]
Computing hash join...  [4.976s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [31.907s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.13s]
Clearing query masking...  [1.532s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.548s]
Sorting trace points...  [1.343s]
Computing alignments...  [32.587s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.043s]
Computing alignments...  [32.436s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.257s]
Computing alignments...  [32.806s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.236s]
Computing alignments...  [32.461s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.088s]
Sorting trace points...  [1.198s]
Computing alignments...  [32.287s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.067s]
Sorting trace points...  [0.948s]
Computing alignments...  [31.971s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.243s]
Computing alignments...  [32.082s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.227s]
Computing alignments...  [31.923s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.267s]
Computing alignments...  [33.576s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.329s]
Computing alignments...  [34.458s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.033s]
Computing alignments...  [34.605s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.354s]
Computing alignments...  [34.636s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.086s]
Computing alignments...  [34.471s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.909s]
Sorting trace points...  [1.39s]
Computing alignments...  [34.647s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.348s]
Computing alignments...  [34.552s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.309s]
Computing alignments...  [34.243s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [562.032s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.396s]
Masking reference...  [30.846s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.316s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.359s]
Building query seed array...  [2.112s]
Computing hash join...  [5.204s]
Masking low complexity seeds...  [0.256s]
Searching alignments...  [80.751s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.962s]
Building query seed array...  [2.601s]
Computing hash join...  [5.114s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [50.178s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.935s]
Building query seed array...  [2.606s]
Computing hash join...  [5.181s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [46.2s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.472s]
Building query seed array...  [2.094s]
Computing hash join...  [5.156s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [41.005s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.814s]
Building query seed array...  [1.981s]
Computing hash join...  [4.956s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [42.008s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.279s]
Building query seed array...  [2.181s]
Computing hash join...  [5.017s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [33.909s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.477s]
Building query seed array...  [2.334s]
Computing hash join...  [4.933s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [36.744s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.066s]
Building query seed array...  [1.883s]
Computing hash join...  [4.957s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [30.806s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.562s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.687s]
Sorting trace points...  [1.313s]
Computing alignments...  [32.891s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.049s]
Sorting trace points...  [0.982s]
Computing alignments...  [32.548s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.124s]
Computing alignments...  [32.935s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.252s]
Sorting trace points...  [1.243s]
Computing alignments...  [32.477s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.004s]
Computing alignments...  [32.245s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.038s]
Computing alignments...  [31.938s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.227s]
Computing alignments...  [32.055s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.877s]
Sorting trace points...  [1.24s]
Computing alignments...  [31.95s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.337s]
Computing alignments...  [33.603s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.337s]
Computing alignments...  [34.493s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.331s]
Computing alignments...  [34.513s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.36s]
Computing alignments...  [34.732s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.1s]
Computing alignments...  [34.677s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.376s]
Computing alignments...  [34.741s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.32s]
Computing alignments...  [34.712s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.341s]
Computing alignments...  [34.401s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
 [563.547s]
Deallocating reference...  [0.064s]
Loading reference sequences...  [29.673s]
Masking reference...  [32.1s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.188s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.426s]
Building query seed array...  [2.109s]
Computing hash join...  [5.233s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [80.734s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.414s]
Building query seed array...  [2.508s]
Computing hash join...  [5.146s]
Masking low complexity seeds...  [0.249s]
Searching alignments...  [51.801s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [12.933s]
Building query seed array...  [2.636s]
Computing hash join...  [5.23s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [45.844s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.353s]
Building query seed array...  [2.066s]
Computing hash join...  [5.179s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [39.866s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.284s]
Building query seed array...  [1.941s]
Computing hash join...  [5.027s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [44.953s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.639s]
Building query seed array...  [2.192s]
Computing hash join...  [5.07s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [33.231s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.184s]
Building query seed array...  [2.282s]
Computing hash join...  [5.018s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [36.301s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.862s]
Building query seed array...  [1.986s]
Computing hash join...  [4.99s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [30.861s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.127s]
Clearing query masking...  [1.629s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.081s]
Sorting trace points...  [1.234s]
Computing alignments...  [32.829s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.126s]
Sorting trace points...  [1.059s]
Computing alignments...  [32.506s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.082s]
Sorting trace points...  [0.954s]
Computing alignments...  [32.772s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.002s]
Sorting trace points...  [1.247s]
Computing alignments...  [32.396s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.063s]
Sorting trace points...  [0.964s]
Computing alignments...  [32.124s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.221s]
Computing alignments...  [31.909s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.232s]
Computing alignments...  [31.99s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.169s]
Computing alignments...  [31.823s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.228s]
Computing alignments...  [33.99s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.231s]
Computing alignments...  [34.285s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.087s]
Sorting trace points...  [1.148s]
Computing alignments...  [34.44s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.049s]
Computing alignments...  [34.468s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.264s]
Computing alignments...  [34.463s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.383s]
Computing alignments...  [34.563s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.306s]
Computing alignments...  [34.588s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.323s]
Computing alignments...  [34.266s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0s]
 [560.806s]
Deallocating reference...  [0.069s]
Loading reference sequences...  [29.505s]
Masking reference...  [30.831s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.062s]
Allocating buffers...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.122s]
Building query seed array...  [2.151s]
Computing hash join...  [5.266s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [82.05s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.32s]
Building query seed array...  [2.402s]
Computing hash join...  [5.192s]
Masking low complexity seeds...  [0.249s]
Searching alignments...  [52.937s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.843s]
Building query seed array...  [2.522s]
Computing hash join...  [5.183s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [45.912s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.144s]
Building query seed array...  [2.136s]
Computing hash join...  [5.274s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [41.606s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.978s]
Building query seed array...  [1.89s]
Computing hash join...  [5.075s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [44.273s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.226s]
Building query seed array...  [2.231s]
Computing hash join...  [4.982s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [33.631s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.216s]
Building query seed array...  [2.327s]
Computing hash join...  [4.965s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [37.656s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.571s]
Building query seed array...  [1.935s]
Computing hash join...  [4.918s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [30.78s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.65s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.637s]
Sorting trace points...  [1.328s]
Computing alignments...  [32.782s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.268s]
Computing alignments...  [32.452s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.23s]
Computing alignments...  [32.841s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.239s]
Computing alignments...  [32.343s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.103s]
Sorting trace points...  [1.212s]
Computing alignments...  [32.182s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.221s]
Computing alignments...  [31.825s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.211s]
Computing alignments...  [32.007s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.216s]
Computing alignments...  [32.01s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.088s]
Computing alignments...  [33.601s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.272s]
Computing alignments...  [34.367s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.065s]
Computing alignments...  [34.49s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.347s]
Computing alignments...  [34.582s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.309s]
Computing alignments...  [34.462s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.289s]
Computing alignments...  [34.58s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.311s]
Computing alignments...  [34.597s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.339s]
Computing alignments...  [34.299s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
 [561.173s]
Deallocating reference...  [0.057s]
Loading reference sequences...  [29.756s]
Masking reference...  [31.894s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.016s]
Building reference histograms...  [31.982s]
Allocating buffers...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.49s]
Building query seed array...  [2.136s]
Computing hash join...  [5.185s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [79.755s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.328s]
Building query seed array...  [2.382s]
Computing hash join...  [5.285s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [50.443s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.157s]
Building query seed array...  [2.612s]
Computing hash join...  [5.135s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [44.926s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.99s]
Building query seed array...  [2.068s]
Computing hash join...  [5.355s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [38.868s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.851s]
Building query seed array...  [1.941s]
Computing hash join...  [4.975s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [42.595s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.139s]
Building query seed array...  [2.188s]
Computing hash join...  [5.002s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [32.937s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.067s]
Building query seed array...  [2.411s]
Computing hash join...  [4.894s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [36.23s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.964s]
Building query seed array...  [1.936s]
Computing hash join...  [4.928s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [30.349s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.626s]
Opening temporary output file...  [0.003s]
Computing alignments... Loading trace points...  [6.585s]
Sorting trace points...  [1.294s]
Computing alignments...  [32.739s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.198s]
Computing alignments...  [32.399s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.043s]
Sorting trace points...  [0.984s]
Computing alignments...  [33.004s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.11s]
Computing alignments...  [32.27s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.066s]
Sorting trace points...  [0.998s]
Computing alignments...  [32.176s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.13s]
Computing alignments...  [32.013s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.23s]
Computing alignments...  [32.046s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.09s]
Sorting trace points...  [1.154s]
Computing alignments...  [31.927s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.151s]
Computing alignments...  [33.663s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.33s]
Computing alignments...  [34.39s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.035s]
Computing alignments...  [34.431s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.204s]
Computing alignments...  [34.466s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.256s]
Computing alignments...  [34.53s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.323s]
Computing alignments...  [34.539s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.336s]
Computing alignments...  [34.499s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.335s]
Computing alignments...  [34.172s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [560.193s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [29.492s]
Masking reference...  [32.114s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.457s]
Allocating buffers...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.573s]
Building query seed array...  [2.131s]
Computing hash join...  [5.468s]
Masking low complexity seeds...  [0.256s]
Searching alignments...  [80.764s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.508s]
Building query seed array...  [2.4s]
Computing hash join...  [5.196s]
Masking low complexity seeds...  [0.259s]
Searching alignments...  [52.848s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.177s]
Building query seed array...  [2.53s]
Computing hash join...  [5.171s]
Masking low complexity seeds...  [0.256s]
Searching alignments...  [45.16s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.772s]
Building query seed array...  [2.026s]
Computing hash join...  [5.261s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [41.195s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.009s]
Building query seed array...  [1.896s]
Computing hash join...  [5.039s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [44.667s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.645s]
Building query seed array...  [2.182s]
Computing hash join...  [4.996s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [34.587s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.189s]
Building query seed array...  [2.263s]
Computing hash join...  [5.051s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [38.058s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.017s]
Building query seed array...  [1.934s]
Computing hash join...  [4.944s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [31.234s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.127s]
Clearing query masking...  [1.58s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.874s]
Sorting trace points...  [1.171s]
Computing alignments...  [32.663s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.22s]
Computing alignments...  [32.455s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.262s]
Computing alignments...  [32.768s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.202s]
Sorting trace points...  [0.928s]
Computing alignments...  [32.43s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.094s]
Computing alignments...  [32.136s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.056s]
Computing alignments...  [31.866s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.1s]
Sorting trace points...  [0.963s]
Computing alignments...  [32.076s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.205s]
Computing alignments...  [31.925s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.303s]
Computing alignments...  [33.5s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.346s]
Computing alignments...  [34.31s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.309s]
Computing alignments...  [34.406s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.318s]
Computing alignments...  [34.486s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.086s]
Computing alignments...  [34.528s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.308s]
Computing alignments...  [34.659s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.314s]
Computing alignments...  [34.64s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.034s]
Computing alignments...  [34.279s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [560.297s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [29.513s]
Masking reference...  [32.063s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [31.959s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.387s]
Building query seed array...  [2.002s]
Computing hash join...  [5.233s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [81.438s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.446s]
Building query seed array...  [2.419s]
Computing hash join...  [5.194s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [50.779s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.332s]
Building query seed array...  [2.56s]
Computing hash join...  [5.202s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [45.496s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.953s]
Building query seed array...  [2.065s]
Computing hash join...  [5.114s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [39.59s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.735s]
Building query seed array...  [1.892s]
Computing hash join...  [4.992s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [44.98s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.479s]
Building query seed array...  [2.246s]
Computing hash join...  [4.964s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [33.384s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.285s]
Building query seed array...  [2.32s]
Computing hash join...  [5.068s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [37.046s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.924s]
Building query seed array...  [1.891s]
Computing hash join...  [4.969s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [30.677s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.505s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.629s]
Sorting trace points...  [1.309s]
Computing alignments...  [32.848s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.243s]
Computing alignments...  [32.404s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.299s]
Computing alignments...  [32.755s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.002s]
Sorting trace points...  [1.052s]
Computing alignments...  [32.323s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.17s]
Computing alignments...  [32.118s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.115s]
Computing alignments...  [31.821s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.099s]
Sorting trace points...  [0.945s]
Computing alignments...  [32.064s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.186s]
Computing alignments...  [31.792s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.244s]
Computing alignments...  [33.619s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.198s]
Computing alignments...  [34.377s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.341s]
Computing alignments...  [34.436s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.385s]
Computing alignments...  [34.522s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.303s]
Computing alignments...  [34.632s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.346s]
Computing alignments...  [34.59s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.199s]
Sorting trace points...  [1.33s]
Computing alignments...  [34.538s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.312s]
Computing alignments...  [34.14s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [560.756s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [25.386s]
Masking reference...  [24.989s]
Initializing dictionary...  [0.064s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [26.707s]
Allocating buffers...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.398s]
Building query seed array...  [2.098s]
Computing hash join...  [4.294s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [65.391s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [10.108s]
Building query seed array...  [2.473s]
Computing hash join...  [4.295s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [43.185s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [10.596s]
Building query seed array...  [2.672s]
Computing hash join...  [4.317s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [37.309s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [8.138s]
Building query seed array...  [2.141s]
Computing hash join...  [4.303s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [32.478s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [8.115s]
Building query seed array...  [1.944s]
Computing hash join...  [4.209s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [36.534s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [9.725s]
Building query seed array...  [2.174s]
Computing hash join...  [4.137s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [27.448s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [10.362s]
Building query seed array...  [2.448s]
Computing hash join...  [4.246s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [29.973s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [8.105s]
Building query seed array...  [1.937s]
Computing hash join...  [4.297s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [25.586s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.112s]
Clearing query masking...  [1.61s]
Opening temporary output file...  [0.003s]
Computing alignments... Loading trace points...  [10.917s]
Sorting trace points...  [2.13s]
Computing alignments...  [51.715s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.106s]
Sorting trace points...  [1.986s]
Computing alignments...  [51.644s]
Deallocating buffers...  [0.034s]
Loading trace points...  [0.12s]
Sorting trace points...  [2.012s]
Computing alignments...  [50.865s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.157s]
Sorting trace points...  [1.971s]
Computing alignments...  [50.862s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.072s]
Sorting trace points...  [2.01s]
Computing alignments...  [53.914s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.118s]
Sorting trace points...  [1.875s]
Computing alignments...  [54.898s]
Deallocating buffers...  [0.032s]
Loading trace points...  [0.095s]
Sorting trace points...  [2.252s]
Computing alignments...  [54.795s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
Sorting trace points...  [2.099s]
Computing alignments...  [54.319s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0s]
 [451.361s]
Deallocating reference...  [0.049s]
Loading reference sequences...  [0.084s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [1971.69s]
 [1971.69s]
Deallocating queries...  [0.047s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [3.545s]
 [4.556s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 18312.7s
Reported 2478080576 pairwise alignments, 2478080576 HSPs.
13992614 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E13_R2.fastp-trim.20230215.fq.gz complete: E13_R2.blastx.meganized.daa

Now MEGANizing E13_R2.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: E13_R2.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 100% (212.6s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.2s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (4,713.3s)
Total reads:       13,992,614
With hits:          13,992,614 
Alignments:      2,472,068,023
Assig. Taxonomy:    13,071,293
Assig. SEED:            98,006
Assig. EGGNOG:          41,642
Assig. GTDB:           366,149
Assig. EC:           2,240,715
Assig. INTERPRO2GO:  1,174,058
MinSupport set to: 6996
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.4s)
Min-supp. changes:       3,917
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (10.0s)
Min-supp. changes:       2,941
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (34.1s)
Binning reads Syncing
100% (0.3s)
Class. Taxonomy:            67
Class. SEED:               476
Class. EGGNOG:           1,649
Class. GTDB:                15
Class. EC:               2,243
Class. INTERPRO2GO:      7,607
Total time:  4,980s
Peak memory: 30.7 of 195.3G
MEGANization of E13_R2.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E14_R1.fastp-trim.20230215.fq.gz...
963f3644b84a30f3f75a0028a9c73e40  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E14_R1.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E14_R1.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.332s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.735s]
Opening the output file...  [0s]
Loading query sequences...  [69.106s]
Masking queries...  [17.484s]
Algorithm: Double-indexed
Building query histograms...  [16.253s]
Loading reference sequences...  [29.662s]
Masking reference...  [32.09s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.418s]
Allocating buffers...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.317s]
Building query seed array...  [1.941s]
Computing hash join...  [5.186s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [75.745s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [11.969s]
Building query seed array...  [2.301s]
Computing hash join...  [5.12s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [46.616s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.237s]
Building query seed array...  [2.415s]
Computing hash join...  [4.953s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [40.927s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.409s]
Building query seed array...  [1.969s]
Computing hash join...  [5.079s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [36.217s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.775s]
Building query seed array...  [1.794s]
Computing hash join...  [4.863s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [37.147s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.984s]
Building query seed array...  [2.099s]
Computing hash join...  [4.885s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [30.501s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.506s]
Building query seed array...  [2.165s]
Computing hash join...  [4.977s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [33.474s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.612s]
Building query seed array...  [1.772s]
Computing hash join...  [4.849s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [28.951s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.601s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.409s]
Sorting trace points...  [1.097s]
Computing alignments...  [30.712s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.149s]
Computing alignments...  [30.561s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.2s]
Computing alignments...  [30.753s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.086s]
Computing alignments...  [30.298s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.132s]
Computing alignments...  [30.263s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.07s]
Sorting trace points...  [0.872s]
Computing alignments...  [29.857s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.106s]
Computing alignments...  [29.864s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.084s]
Sorting trace points...  [1.143s]
Computing alignments...  [29.409s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.139s]
Computing alignments...  [30.143s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.145s]
Computing alignments...  [30.793s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.065s]
Sorting trace points...  [0.99s]
Computing alignments...  [30.835s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.143s]
Computing alignments...  [30.89s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.181s]
Computing alignments...  [31.139s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.029s]
Computing alignments...  [31.256s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.177s]
Computing alignments...  [31.185s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.232s]
Computing alignments...  [30.922s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
 [514.33s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [31.635s]
Masking reference...  [31.458s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.516s]
Allocating buffers...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.348s]
Building query seed array...  [1.953s]
Computing hash join...  [4.959s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [72.008s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.411s]
Building query seed array...  [2.243s]
Computing hash join...  [5.034s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [46.132s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.355s]
Building query seed array...  [2.425s]
Computing hash join...  [5.015s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [40.743s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.105s]
Building query seed array...  [1.933s]
Computing hash join...  [5.09s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [36.069s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.892s]
Building query seed array...  [1.816s]
Computing hash join...  [4.966s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [36.154s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.255s]
Building query seed array...  [2.072s]
Computing hash join...  [4.9s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [29.464s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.278s]
Building query seed array...  [2.15s]
Computing hash join...  [4.917s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [32.455s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.09s]
Building query seed array...  [1.745s]
Computing hash join...  [4.865s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [27.973s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.131s]
Clearing query masking...  [1.527s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.203s]
Sorting trace points...  [1.192s]
Computing alignments...  [30.423s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.259s]
Sorting trace points...  [1.15s]
Computing alignments...  [30.244s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.161s]
Computing alignments...  [30.486s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.171s]
Computing alignments...  [30.184s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.063s]
Sorting trace points...  [0.888s]
Computing alignments...  [30.073s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.061s]
Computing alignments...  [29.679s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.101s]
Sorting trace points...  [1.061s]
Computing alignments...  [29.696s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.009s]
Computing alignments...  [29.216s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.139s]
Computing alignments...  [29.775s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.154s]
Computing alignments...  [30.692s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.059s]
Sorting trace points...  [0.934s]
Computing alignments...  [30.633s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.046s]
Sorting trace points...  [0.925s]
Computing alignments...  [30.725s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.185s]
Computing alignments...  [30.804s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.095s]
Sorting trace points...  [1.176s]
Computing alignments...  [30.927s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.139s]
Computing alignments...  [30.991s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [0.903s]
Computing alignments...  [30.811s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
 [510.27s]
Deallocating reference...  [0.066s]
Loading reference sequences...  [31.843s]
Masking reference...  [32.146s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [31.792s]
Allocating buffers...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.44s]
Building query seed array...  [1.982s]
Computing hash join...  [5.122s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [76.195s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.415s]
Building query seed array...  [2.293s]
Computing hash join...  [5.038s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [47.354s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [14.278s]
Building query seed array...  [2.476s]
Computing hash join...  [5.024s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [40.861s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.245s]
Building query seed array...  [1.991s]
Computing hash join...  [5.089s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [38.147s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.876s]
Building query seed array...  [1.774s]
Computing hash join...  [4.812s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [37.153s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.106s]
Building query seed array...  [2.083s]
Computing hash join...  [4.862s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [29.846s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.257s]
Building query seed array...  [2.191s]
Computing hash join...  [4.89s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [32.861s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.852s]
Building query seed array...  [1.772s]
Computing hash join...  [4.914s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [27.858s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.132s]
Clearing query masking...  [1.516s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.317s]
Sorting trace points...  [1.189s]
Computing alignments...  [30.517s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.105s]
Sorting trace points...  [1.146s]
Computing alignments...  [30.307s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.155s]
Computing alignments...  [30.709s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.153s]
Computing alignments...  [30.343s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.134s]
Computing alignments...  [30.101s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.084s]
Sorting trace points...  [1.156s]
Computing alignments...  [30.345s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.042s]
Sorting trace points...  [1.016s]
Computing alignments...  [29.857s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.069s]
Sorting trace points...  [0.836s]
Computing alignments...  [29.36s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.094s]
Sorting trace points...  [1.15s]
Computing alignments...  [29.94s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.205s]
Computing alignments...  [30.746s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.052s]
Sorting trace points...  [0.928s]
Computing alignments...  [30.734s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.156s]
Computing alignments...  [30.69s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.197s]
Computing alignments...  [30.837s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.169s]
Computing alignments...  [30.876s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.162s]
Computing alignments...  [30.933s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.156s]
Computing alignments...  [30.679s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [512.483s]
Deallocating reference...  [0.07s]
Loading reference sequences...  [29.661s]
Masking reference...  [30.864s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.9s]
Allocating buffers...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.534s]
Building query seed array...  [1.921s]
Computing hash join...  [5.085s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [73.718s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.686s]
Building query seed array...  [2.275s]
Computing hash join...  [5.03s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [46.706s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.195s]
Building query seed array...  [2.401s]
Computing hash join...  [4.98s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [41.713s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.249s]
Building query seed array...  [1.942s]
Computing hash join...  [4.963s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [37.082s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.937s]
Building query seed array...  [1.826s]
Computing hash join...  [4.787s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [36.743s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.455s]
Building query seed array...  [2.137s]
Computing hash join...  [4.798s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [29.749s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.941s]
Building query seed array...  [2.206s]
Computing hash join...  [4.877s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [32.315s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.831s]
Building query seed array...  [1.737s]
Computing hash join...  [4.875s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [27.754s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.139s]
Clearing query masking...  [1.581s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.08s]
Sorting trace points...  [1.205s]
Computing alignments...  [30.583s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.146s]
Computing alignments...  [30.468s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.074s]
Sorting trace points...  [0.907s]
Computing alignments...  [30.563s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.013s]
Computing alignments...  [30.169s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.123s]
Computing alignments...  [30.118s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.119s]
Computing alignments...  [29.764s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.175s]
Computing alignments...  [29.709s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.082s]
Computing alignments...  [29.328s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.153s]
Computing alignments...  [29.985s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.011s]
Computing alignments...  [30.799s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.052s]
Sorting trace points...  [0.896s]
Computing alignments...  [30.746s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.161s]
Computing alignments...  [30.81s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.17s]
Computing alignments...  [30.909s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.161s]
Computing alignments...  [30.968s]
Deallocating buffers...  [0.015s]
Loading trace points...  [1.221s]
Sorting trace points...  [1.194s]
Computing alignments...  [30.978s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.195s]
Computing alignments...  [30.832s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [512.893s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [31.541s]
Masking reference...  [30.867s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.286s]
Allocating buffers...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.313s]
Building query seed array...  [1.957s]
Computing hash join...  [5.051s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [70.538s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.043s]
Building query seed array...  [2.242s]
Computing hash join...  [5.02s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [47.779s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.606s]
Building query seed array...  [2.357s]
Computing hash join...  [4.955s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [42.251s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.885s]
Building query seed array...  [1.925s]
Computing hash join...  [5.028s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [37.74s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.043s]
Building query seed array...  [1.734s]
Computing hash join...  [4.854s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [37.252s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.395s]
Building query seed array...  [2.009s]
Computing hash join...  [4.9s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [30.047s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.146s]
Building query seed array...  [2.154s]
Computing hash join...  [4.808s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [32.306s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.041s]
Building query seed array...  [1.745s]
Computing hash join...  [4.831s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [27.814s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.134s]
Clearing query masking...  [1.499s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.115s]
Sorting trace points...  [1.203s]
Computing alignments...  [30.446s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.064s]
Sorting trace points...  [0.918s]
Computing alignments...  [30.343s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.133s]
Computing alignments...  [30.538s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.129s]
Computing alignments...  [30.156s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.105s]
Computing alignments...  [29.987s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.037s]
Computing alignments...  [29.807s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.115s]
Computing alignments...  [29.742s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.087s]
Sorting trace points...  [1.079s]
Computing alignments...  [29.179s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.093s]
Computing alignments...  [29.898s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.058s]
Sorting trace points...  [0.95s]
Computing alignments...  [30.639s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.172s]
Computing alignments...  [30.622s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.162s]
Computing alignments...  [30.664s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.35s]
Sorting trace points...  [1.213s]
Computing alignments...  [30.741s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.176s]
Computing alignments...  [30.813s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.179s]
Computing alignments...  [31.004s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.045s]
Computing alignments...  [30.81s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [510.569s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [30.472s]
Masking reference...  [31.262s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.011s]
Building reference histograms...  [32.44s]
Allocating buffers...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.18s]
Building query seed array...  [1.979s]
Computing hash join...  [4.96s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [70.226s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.218s]
Building query seed array...  [2.26s]
Computing hash join...  [5.178s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [46.708s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.619s]
Building query seed array...  [2.348s]
Computing hash join...  [4.953s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [40.906s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.846s]
Building query seed array...  [1.924s]
Computing hash join...  [5.097s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [36.595s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.038s]
Building query seed array...  [1.881s]
Computing hash join...  [4.913s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [37.54s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.942s]
Building query seed array...  [2.018s]
Computing hash join...  [4.905s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [29.485s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.603s]
Building query seed array...  [2.22s]
Computing hash join...  [4.901s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [32.051s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.302s]
Building query seed array...  [1.789s]
Computing hash join...  [4.865s]
Masking low complexity seeds...  [0.224s]
Searching alignments...  [26.784s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.122s]
Clearing query masking...  [1.459s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [5.978s]
Sorting trace points...  [1.197s]
Computing alignments...  [30.105s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.151s]
Computing alignments...  [30.014s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.134s]
Computing alignments...  [30.425s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.124s]
Computing alignments...  [29.936s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.062s]
Sorting trace points...  [0.936s]
Computing alignments...  [29.719s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.075s]
Sorting trace points...  [0.95s]
Computing alignments...  [29.406s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.083s]
Sorting trace points...  [0.966s]
Computing alignments...  [29.616s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.134s]
Computing alignments...  [29.117s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.066s]
Sorting trace points...  [0.947s]
Computing alignments...  [29.735s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.085s]
Computing alignments...  [30.491s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.178s]
Computing alignments...  [30.461s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.038s]
Sorting trace points...  [1.18s]
Computing alignments...  [30.535s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.035s]
Computing alignments...  [30.742s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.05s]
Sorting trace points...  [0.942s]
Computing alignments...  [30.82s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.168s]
Computing alignments...  [30.837s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.072s]
Computing alignments...  [30.638s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
 [506.93s]
Deallocating reference...  [0.067s]
Loading reference sequences...  [32.463s]
Masking reference...  [31.914s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [31.514s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [9.86s]
Building query seed array...  [1.949s]
Computing hash join...  [5.08s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [74.011s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.376s]
Building query seed array...  [2.204s]
Computing hash join...  [5.023s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [48.84s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.172s]
Building query seed array...  [2.441s]
Computing hash join...  [4.997s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [41.165s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.173s]
Building query seed array...  [1.965s]
Computing hash join...  [4.958s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [39.305s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.048s]
Building query seed array...  [1.801s]
Computing hash join...  [4.825s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [37.975s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.265s]
Building query seed array...  [2.094s]
Computing hash join...  [4.859s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [29.321s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.844s]
Building query seed array...  [2.177s]
Computing hash join...  [4.835s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [32.758s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.729s]
Building query seed array...  [1.727s]
Computing hash join...  [4.858s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [28.386s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.121s]
Clearing query masking...  [1.487s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.149s]
Sorting trace points...  [1.226s]
Computing alignments...  [30.574s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.11s]
Sorting trace points...  [1.137s]
Computing alignments...  [30.333s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.188s]
Computing alignments...  [30.52s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.131s]
Computing alignments...  [30.188s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.068s]
Sorting trace points...  [0.916s]
Computing alignments...  [30.063s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.152s]
Computing alignments...  [29.831s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.129s]
Computing alignments...  [29.745s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.141s]
Computing alignments...  [29.23s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.045s]
Sorting trace points...  [0.845s]
Computing alignments...  [29.944s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.187s]
Computing alignments...  [30.708s]
Deallocating buffers...  [0.019s]
Loading trace points...  [1.248s]
Sorting trace points...  [1.104s]
Computing alignments...  [30.743s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.183s]
Computing alignments...  [30.75s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.094s]
Computing alignments...  [30.911s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.19s]
Computing alignments...  [30.918s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.062s]
Sorting trace points...  [0.994s]
Computing alignments...  [31.015s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.169s]
Computing alignments...  [30.86s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [512.68s]
Deallocating reference...  [0.069s]
Loading reference sequences...  [29.728s]
Masking reference...  [30.855s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.694s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.122s]
Building query seed array...  [1.975s]
Computing hash join...  [5.064s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [71.751s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.428s]
Building query seed array...  [2.31s]
Computing hash join...  [5.153s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [47.987s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.874s]
Building query seed array...  [2.421s]
Computing hash join...  [5.028s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [41.218s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.963s]
Building query seed array...  [1.898s]
Computing hash join...  [4.974s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [37.556s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.213s]
Building query seed array...  [1.741s]
Computing hash join...  [4.79s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [37.982s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.791s]
Building query seed array...  [2.068s]
Computing hash join...  [4.82s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [29.748s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.983s]
Building query seed array...  [2.204s]
Computing hash join...  [4.852s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [32.565s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.964s]
Building query seed array...  [1.728s]
Computing hash join...  [4.827s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [27.783s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.122s]
Clearing query masking...  [1.502s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.014s]
Sorting trace points...  [1.18s]
Computing alignments...  [30.608s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.075s]
Computing alignments...  [30.416s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.16s]
Computing alignments...  [30.519s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [0.916s]
Computing alignments...  [30.098s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.055s]
Sorting trace points...  [0.975s]
Computing alignments...  [30.044s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.118s]
Computing alignments...  [29.774s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.097s]
Computing alignments...  [29.873s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.085s]
Sorting trace points...  [1.099s]
Computing alignments...  [29.312s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.377s]
Sorting trace points...  [1.159s]
Computing alignments...  [30.002s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.042s]
Sorting trace points...  [1.134s]
Computing alignments...  [30.849s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.182s]
Computing alignments...  [30.793s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.06s]
Sorting trace points...  [0.873s]
Computing alignments...  [30.842s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.143s]
Computing alignments...  [30.99s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.195s]
Computing alignments...  [31.114s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.095s]
Sorting trace points...  [1.191s]
Computing alignments...  [31.153s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.195s]
Computing alignments...  [30.979s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
 [512.57s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.703s]
Masking reference...  [30.902s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.118s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.501s]
Building query seed array...  [1.951s]
Computing hash join...  [5.017s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [73.988s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.613s]
Building query seed array...  [2.311s]
Computing hash join...  [5.081s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [48.299s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [14.028s]
Building query seed array...  [2.388s]
Computing hash join...  [4.953s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [41.765s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.996s]
Building query seed array...  [1.965s]
Computing hash join...  [4.948s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [37.558s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.055s]
Building query seed array...  [1.739s]
Computing hash join...  [4.831s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [36.557s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.378s]
Building query seed array...  [2.141s]
Computing hash join...  [4.868s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [30.583s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.167s]
Building query seed array...  [2.226s]
Computing hash join...  [4.8s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [32.247s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.876s]
Building query seed array...  [1.78s]
Computing hash join...  [4.833s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [27.529s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.136s]
Clearing query masking...  [1.521s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.019s]
Sorting trace points...  [1.207s]
Computing alignments...  [30.43s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.181s]
Computing alignments...  [30.235s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.846s]
Sorting trace points...  [1.189s]
Computing alignments...  [30.473s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.092s]
Sorting trace points...  [1.124s]
Computing alignments...  [30.028s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.17s]
Computing alignments...  [29.909s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.107s]
Computing alignments...  [29.697s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.121s]
Computing alignments...  [29.676s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.099s]
Computing alignments...  [29.164s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.156s]
Computing alignments...  [29.79s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.061s]
Sorting trace points...  [0.895s]
Computing alignments...  [30.674s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.169s]
Computing alignments...  [30.618s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.042s]
Sorting trace points...  [1.186s]
Computing alignments...  [31.422s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.171s]
Computing alignments...  [30.871s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.026s]
Computing alignments...  [30.905s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.179s]
Computing alignments...  [30.894s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.211s]
Computing alignments...  [30.799s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [511.829s]
Deallocating reference...  [0.073s]
Loading reference sequences...  [29.594s]
Masking reference...  [30.833s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.48s]
Allocating buffers...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.315s]
Building query seed array...  [1.975s]
Computing hash join...  [5.046s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [73.823s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [11.891s]
Building query seed array...  [2.319s]
Computing hash join...  [4.949s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [48.637s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [12.945s]
Building query seed array...  [2.366s]
Computing hash join...  [5.031s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [42.182s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.305s]
Building query seed array...  [2.011s]
Computing hash join...  [5.024s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [38.634s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.021s]
Building query seed array...  [1.843s]
Computing hash join...  [4.933s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [38.052s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.957s]
Building query seed array...  [2.095s]
Computing hash join...  [4.94s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [30.266s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.211s]
Building query seed array...  [2.133s]
Computing hash join...  [4.794s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [33.788s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.938s]
Building query seed array...  [1.77s]
Computing hash join...  [4.875s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [28.27s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.133s]
Clearing query masking...  [1.489s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.128s]
Sorting trace points...  [1.203s]
Computing alignments...  [30.395s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.142s]
Computing alignments...  [30.287s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.159s]
Computing alignments...  [30.442s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.139s]
Computing alignments...  [30.097s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.129s]
Computing alignments...  [29.97s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.012s]
Computing alignments...  [29.663s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.137s]
Computing alignments...  [29.61s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.075s]
Computing alignments...  [29.138s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0s]
Sorting trace points...  [1.157s]
Computing alignments...  [29.798s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.221s]
Computing alignments...  [30.585s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.061s]
Sorting trace points...  [0.889s]
Computing alignments...  [30.586s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.067s]
Computing alignments...  [30.604s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.195s]
Computing alignments...  [30.79s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.156s]
Computing alignments...  [30.816s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.157s]
Computing alignments...  [30.926s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.174s]
Computing alignments...  [30.699s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
 [510.462s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [29.672s]
Masking reference...  [30.823s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.621s]
Allocating buffers...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.319s]
Building query seed array...  [1.981s]
Computing hash join...  [5.134s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [72.617s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.338s]
Building query seed array...  [2.3s]
Computing hash join...  [5.077s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [46.722s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.663s]
Building query seed array...  [2.414s]
Computing hash join...  [5.077s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [40.538s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.131s]
Building query seed array...  [1.902s]
Computing hash join...  [5.042s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [37.691s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.006s]
Building query seed array...  [1.767s]
Computing hash join...  [4.773s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [36.625s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.503s]
Building query seed array...  [2.02s]
Computing hash join...  [4.828s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [30.503s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.102s]
Building query seed array...  [2.21s]
Computing hash join...  [4.866s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [32.642s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.788s]
Building query seed array...  [1.745s]
Computing hash join...  [4.828s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [27.221s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.121s]
Clearing query masking...  [1.47s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.178s]
Sorting trace points...  [1.214s]
Computing alignments...  [30.441s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.113s]
Computing alignments...  [30.157s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.155s]
Computing alignments...  [30.55s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.102s]
Sorting trace points...  [0.973s]
Computing alignments...  [30.218s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.129s]
Computing alignments...  [29.954s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.148s]
Computing alignments...  [29.647s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.091s]
Sorting trace points...  [1.169s]
Computing alignments...  [29.548s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.13s]
Computing alignments...  [29.069s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.071s]
Sorting trace points...  [0.949s]
Computing alignments...  [29.814s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.096s]
Sorting trace points...  [1.17s]
Computing alignments...  [30.548s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.005s]
Sorting trace points...  [1.142s]
Computing alignments...  [30.543s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.188s]
Computing alignments...  [30.591s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.189s]
Computing alignments...  [30.672s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.152s]
Computing alignments...  [30.724s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.16s]
Computing alignments...  [30.884s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
Sorting trace points...  [1.183s]
Computing alignments...  [30.638s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [509.623s]
Deallocating reference...  [0.074s]
Loading reference sequences...  [32.471s]
Masking reference...  [31.973s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [31.788s]
Allocating buffers...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.056s]
Building query seed array...  [1.951s]
Computing hash join...  [5.069s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [74.946s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.264s]
Building query seed array...  [2.333s]
Computing hash join...  [4.978s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [47.481s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.104s]
Building query seed array...  [2.37s]
Computing hash join...  [4.983s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [40.412s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.525s]
Building query seed array...  [1.938s]
Computing hash join...  [5.108s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [36.101s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.14s]
Building query seed array...  [1.805s]
Computing hash join...  [4.868s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [37.295s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.136s]
Building query seed array...  [2.164s]
Computing hash join...  [4.799s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [29.961s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.416s]
Building query seed array...  [2.221s]
Computing hash join...  [4.862s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [32.279s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.711s]
Building query seed array...  [1.771s]
Computing hash join...  [4.906s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [27.887s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.128s]
Clearing query masking...  [1.492s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.139s]
Sorting trace points...  [1.233s]
Computing alignments...  [30.338s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.166s]
Sorting trace points...  [1.193s]
Computing alignments...  [30.166s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.154s]
Computing alignments...  [30.408s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.074s]
Sorting trace points...  [0.889s]
Computing alignments...  [30.047s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.118s]
Computing alignments...  [29.938s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.063s]
Sorting trace points...  [0.928s]
Computing alignments...  [29.832s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.094s]
Computing alignments...  [29.759s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.112s]
Computing alignments...  [29.287s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.002s]
Sorting trace points...  [1.129s]
Computing alignments...  [29.905s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.034s]
Sorting trace points...  [1.175s]
Computing alignments...  [30.668s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.218s]
Computing alignments...  [30.712s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.14s]
Computing alignments...  [30.68s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.18s]
Computing alignments...  [30.862s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.042s]
Sorting trace points...  [1.112s]
Computing alignments...  [31.008s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.055s]
Sorting trace points...  [0.871s]
Computing alignments...  [31s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [1.191s]
Computing alignments...  [30.873s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
 [510.536s]
Deallocating reference...  [0.076s]
Loading reference sequences...  [31.709s]
Masking reference...  [32.138s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.252s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.17s]
Building query seed array...  [1.871s]
Computing hash join...  [5.111s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [74.811s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.42s]
Building query seed array...  [2.323s]
Computing hash join...  [5.065s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [47.187s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.247s]
Building query seed array...  [2.231s]
Computing hash join...  [4.991s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [40.223s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.833s]
Building query seed array...  [1.907s]
Computing hash join...  [5.002s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [36.07s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.52s]
Building query seed array...  [1.774s]
Computing hash join...  [4.914s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [36.75s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.741s]
Building query seed array...  [2.129s]
Computing hash join...  [4.806s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [29.824s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.266s]
Building query seed array...  [2.143s]
Computing hash join...  [4.952s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [32.792s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.323s]
Building query seed array...  [1.739s]
Computing hash join...  [4.856s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [28.144s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.128s]
Clearing query masking...  [1.494s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [5.89s]
Sorting trace points...  [1.227s]
Computing alignments...  [30.523s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.085s]
Sorting trace points...  [0.972s]
Computing alignments...  [30.318s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.15s]
Computing alignments...  [30.547s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.061s]
Sorting trace points...  [0.872s]
Computing alignments...  [30.221s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.135s]
Computing alignments...  [29.999s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.162s]
Computing alignments...  [29.91s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.133s]
Computing alignments...  [29.631s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.063s]
Sorting trace points...  [0.967s]
Computing alignments...  [29.063s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.155s]
Computing alignments...  [29.757s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.152s]
Computing alignments...  [30.589s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.167s]
Computing alignments...  [30.527s]
Deallocating buffers...  [0.018s]
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Sorting trace points...  [1.14s]
Computing alignments...  [30.564s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.175s]
Computing alignments...  [30.693s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.207s]
Computing alignments...  [30.812s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.214s]
Computing alignments...  [30.825s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [0.964s]
Computing alignments...  [30.688s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [509.484s]
Deallocating reference...  [0.07s]
Loading reference sequences...  [23.624s]
Masking reference...  [25.968s]
Initializing dictionary...  [0.064s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [26.576s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.452s]
Building query seed array...  [1.95s]
Computing hash join...  [4.231s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [55.94s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [10.623s]
Building query seed array...  [2.31s]
Computing hash join...  [4.27s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [37.343s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [10.693s]
Building query seed array...  [2.377s]
Computing hash join...  [4.212s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [32.756s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [7.969s]
Building query seed array...  [1.95s]
Computing hash join...  [4.201s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [30.007s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [8.287s]
Building query seed array...  [1.756s]
Computing hash join...  [4.041s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [30.606s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [9.967s]
Building query seed array...  [2.055s]
Computing hash join...  [4.012s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [24.595s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [10.644s]
Building query seed array...  [2.184s]
Computing hash join...  [3.965s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [26.547s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [8.201s]
Building query seed array...  [1.766s]
Computing hash join...  [4.066s]
Masking low complexity seeds...  [0.196s]
Searching alignments...  [23.618s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.111s]
Clearing query masking...  [1.519s]
Opening temporary output file...  [0.002s]
Computing alignments... Loading trace points...  [10.183s]
Sorting trace points...  [1.963s]
Computing alignments...  [48.231s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.164s]
Sorting trace points...  [1.872s]
Computing alignments...  [48.081s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.149s]
Sorting trace points...  [1.801s]
Computing alignments...  [47.204s]
Deallocating buffers...  [0.026s]
Loading trace points...  [1.437s]
Sorting trace points...  [1.874s]
Computing alignments...  [46.713s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.146s]
Sorting trace points...  [1.557s]
Computing alignments...  [48.078s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0.135s]
Sorting trace points...  [1.902s]
Computing alignments...  [48.692s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.537s]
Computing alignments...  [48.964s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
Sorting trace points...  [1.883s]
Computing alignments...  [48.732s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0s]
 [411.654s]
Deallocating reference...  [0.049s]
Loading reference sequences...  [0.092s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [1806.8s]
 [1806.8s]
Deallocating queries...  [0.059s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [4.215s]
 [5.471s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 16883.1s
Reported 2288221557 pairwise alignments, 2288221557 HSPs.
12672493 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E14_R1.fastp-trim.20230215.fq.gz complete: E14_R1.blastx.meganized.daa

Now MEGANizing E14_R1.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: E14_R1.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 80% 100% (293.5s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.4s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (4,349.4s)
Total reads:       12,672,493
With hits:          12,672,493 
Alignments:      2,275,863,810
Assig. Taxonomy:    11,484,450
Assig. SEED:           118,584
Assig. EGGNOG:          66,418
Assig. GTDB:           409,863
Assig. EC:           1,924,969
Assig. INTERPRO2GO:  1,164,188
MinSupport set to: 6336
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.4s)
Min-supp. changes:       4,393
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (11.8s)
Min-supp. changes:       3,532
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (27.4s)
Binning reads Syncing
100% (0.4s)
Class. Taxonomy:            87
Class. SEED:               522
Class. EGGNOG:           1,857
Class. GTDB:                24
Class. EC:               2,463
Class. INTERPRO2GO:      7,929
Total time:  4,692s
Peak memory: 34.2 of 195.3G
MEGANization of E14_R1.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E14_R2.fastp-trim.20230215.fq.gz...
ec70e6a2ab72bab174173c5c0ea21d8a  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E14_R2.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E14_R2.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.31s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.774s]
Opening the output file...  [0s]
Loading query sequences...  [69.785s]
Masking queries...  [17.78s]
Algorithm: Double-indexed
Building query histograms...  [16.835s]
Loading reference sequences...  [29.287s]
Masking reference...  [32.052s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.155s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.427s]
Building query seed array...  [1.942s]
Computing hash join...  [5.349s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [72.719s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.568s]
Building query seed array...  [2.283s]
Computing hash join...  [5.157s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [47.323s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.703s]
Building query seed array...  [2.421s]
Computing hash join...  [5.214s]
Masking low complexity seeds...  [0.265s]
Searching alignments...  [41.853s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.791s]
Building query seed array...  [1.928s]
Computing hash join...  [5.14s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [36.806s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.978s]
Building query seed array...  [1.797s]
Computing hash join...  [4.953s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [40.923s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.308s]
Building query seed array...  [2.086s]
Computing hash join...  [5.015s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [30.387s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.717s]
Building query seed array...  [2.187s]
Computing hash join...  [4.892s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [33.858s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.808s]
Building query seed array...  [1.74s]
Computing hash join...  [4.901s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [28.95s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.121s]
Clearing query masking...  [1.564s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.105s]
Sorting trace points...  [1.179s]
Computing alignments...  [30.222s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.127s]
Computing alignments...  [30.363s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.089s]
Sorting trace points...  [1.029s]
Computing alignments...  [30.304s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.117s]
Sorting trace points...  [1.043s]
Computing alignments...  [29.776s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.111s]
Computing alignments...  [29.817s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.097s]
Computing alignments...  [29.42s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.047s]
Sorting trace points...  [0.879s]
Computing alignments...  [29.658s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.096s]
Computing alignments...  [29.037s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.071s]
Sorting trace points...  [0.933s]
Computing alignments...  [30.189s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.169s]
Sorting trace points...  [1.08s]
Computing alignments...  [31.166s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.042s]
Sorting trace points...  [1.175s]
Computing alignments...  [31.476s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.973s]
Sorting trace points...  [1.264s]
Computing alignments...  [31.456s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.165s]
Computing alignments...  [31.54s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.238s]
Computing alignments...  [31.694s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.217s]
Computing alignments...  [31.722s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [0.917s]
Computing alignments...  [31.384s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
 [515.156s]
Deallocating reference...  [0.073s]
Loading reference sequences...  [29.67s]
Masking reference...  [30.869s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.34s]
Allocating buffers...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.248s]
Building query seed array...  [1.983s]
Computing hash join...  [5.156s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [70.903s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.592s]
Building query seed array...  [2.345s]
Computing hash join...  [5.181s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [45.764s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.508s]
Building query seed array...  [2.388s]
Computing hash join...  [5.084s]
Masking low complexity seeds...  [0.256s]
Searching alignments...  [40.658s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.17s]
Building query seed array...  [1.901s]
Computing hash join...  [5.128s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [36.198s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.997s]
Building query seed array...  [1.76s]
Computing hash join...  [4.976s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [39.376s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.054s]
Building query seed array...  [2.039s]
Computing hash join...  [5.014s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [30.29s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.347s]
Building query seed array...  [2.122s]
Computing hash join...  [4.937s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [33.81s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.812s]
Building query seed array...  [1.772s]
Computing hash join...  [4.911s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [27.621s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.127s]
Clearing query masking...  [1.565s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.108s]
Sorting trace points...  [1.164s]
Computing alignments...  [30.094s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.086s]
Sorting trace points...  [0.994s]
Computing alignments...  [30.63s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.1s]
Computing alignments...  [30.256s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.128s]
Computing alignments...  [29.571s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.089s]
Computing alignments...  [29.782s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.126s]
Computing alignments...  [29.367s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.055s]
Sorting trace points...  [0.86s]
Computing alignments...  [29.607s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.116s]
Computing alignments...  [29.176s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.105s]
Computing alignments...  [30.098s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.177s]
Computing alignments...  [31.172s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.168s]
Computing alignments...  [31.281s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.121s]
Computing alignments...  [31.362s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.217s]
Computing alignments...  [31.418s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.191s]
Computing alignments...  [31.531s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.17s]
Computing alignments...  [31.591s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.2s]
Computing alignments...  [31.338s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
 [513.496s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.779s]
Masking reference...  [30.874s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.46s]
Allocating buffers...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.118s]
Building query seed array...  [1.99s]
Computing hash join...  [5.122s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [72.739s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.667s]
Building query seed array...  [2.262s]
Computing hash join...  [5.119s]
Masking low complexity seeds...  [0.256s]
Searching alignments...  [47.284s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.788s]
Building query seed array...  [2.501s]
Computing hash join...  [5.271s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [40.787s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.087s]
Building query seed array...  [1.966s]
Computing hash join...  [5.148s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [36.953s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.817s]
Building query seed array...  [1.791s]
Computing hash join...  [4.975s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [39.632s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.707s]
Building query seed array...  [2.112s]
Computing hash join...  [4.884s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [30.552s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.193s]
Building query seed array...  [2.265s]
Computing hash join...  [4.927s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [33.764s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.105s]
Building query seed array...  [1.826s]
Computing hash join...  [4.931s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [29.383s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.121s]
Clearing query masking...  [1.49s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.136s]
Sorting trace points...  [1.178s]
Computing alignments...  [30.1s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.08s]
Computing alignments...  [30.415s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.087s]
Sorting trace points...  [1.13s]
Computing alignments...  [30.455s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.062s]
Sorting trace points...  [0.886s]
Computing alignments...  [29.845s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.118s]
Computing alignments...  [29.839s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.093s]
Computing alignments...  [29.416s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.149s]
Computing alignments...  [29.593s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.049s]
Sorting trace points...  [0.898s]
Computing alignments...  [28.99s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.085s]
Sorting trace points...  [0.834s]
Computing alignments...  [30.121s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.183s]
Computing alignments...  [31.056s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.033s]
Sorting trace points...  [1.213s]
Computing alignments...  [31.353s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.05s]
Sorting trace points...  [0.931s]
Computing alignments...  [31.367s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.177s]
Computing alignments...  [31.339s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.161s]
Computing alignments...  [31.457s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.188s]
Computing alignments...  [31.527s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [1.192s]
Computing alignments...  [31.277s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
 [512.962s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.536s]
Masking reference...  [32.131s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.287s]
Allocating buffers...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.158s]
Building query seed array...  [1.937s]
Computing hash join...  [5.24s]
Masking low complexity seeds...  [0.259s]
Searching alignments...  [72.789s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.445s]
Building query seed array...  [2.327s]
Computing hash join...  [5.151s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [47.127s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.49s]
Building query seed array...  [2.441s]
Computing hash join...  [5.177s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [42.327s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.805s]
Building query seed array...  [1.847s]
Computing hash join...  [5.202s]
Masking low complexity seeds...  [0.265s]
Searching alignments...  [37.617s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.176s]
Building query seed array...  [1.846s]
Computing hash join...  [4.926s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [38.251s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.529s]
Building query seed array...  [2.092s]
Computing hash join...  [4.959s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [29.937s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.814s]
Building query seed array...  [2.227s]
Computing hash join...  [4.947s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [33.287s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.938s]
Building query seed array...  [1.772s]
Computing hash join...  [4.956s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [28.381s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.133s]
Clearing query masking...  [1.486s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.006s]
Sorting trace points...  [1.151s]
Computing alignments...  [30.247s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.052s]
Sorting trace points...  [0.982s]
Computing alignments...  [30.401s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.143s]
Computing alignments...  [30.368s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.148s]
Computing alignments...  [29.883s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.157s]
Computing alignments...  [29.886s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.267s]
Sorting trace points...  [1.077s]
Computing alignments...  [29.42s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.126s]
Computing alignments...  [29.588s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.113s]
Computing alignments...  [29.043s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.16s]
Computing alignments...  [30.198s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.109s]
Computing alignments...  [31.17s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.15s]
Computing alignments...  [31.524s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.244s]
Computing alignments...  [31.509s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.199s]
Computing alignments...  [31.502s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.206s]
Computing alignments...  [31.582s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.218s]
Computing alignments...  [31.634s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [0.955s]
Computing alignments...  [31.51s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [515.05s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [29.53s]
Masking reference...  [32.13s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.751s]
Allocating buffers...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.27s]
Building query seed array...  [1.948s]
Computing hash join...  [5.241s]
Masking low complexity seeds...  [0.564s]
Searching alignments...  [69.597s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.393s]
Building query seed array...  [2.323s]
Computing hash join...  [5.177s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [47.311s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.677s]
Building query seed array...  [2.455s]
Computing hash join...  [5.154s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [41.669s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.715s]
Building query seed array...  [1.945s]
Computing hash join...  [5.193s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [37.586s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.908s]
Building query seed array...  [1.781s]
Computing hash join...  [4.911s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [39.038s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.221s]
Building query seed array...  [2.009s]
Computing hash join...  [4.918s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [30.164s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.078s]
Building query seed array...  [2.181s]
Computing hash join...  [4.868s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [32.186s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.003s]
Building query seed array...  [1.784s]
Computing hash join...  [5.043s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [28.038s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.139s]
Clearing query masking...  [1.53s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.083s]
Sorting trace points...  [1.15s]
Computing alignments...  [30.163s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.085s]
Sorting trace points...  [1.193s]
Computing alignments...  [30.388s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.022s]
Computing alignments...  [30.301s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.111s]
Sorting trace points...  [1.004s]
Computing alignments...  [29.656s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.095s]
Computing alignments...  [29.77s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.105s]
Computing alignments...  [29.245s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.125s]
Computing alignments...  [29.541s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.013s]
Computing alignments...  [28.856s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.06s]
Sorting trace points...  [0.923s]
Computing alignments...  [30.035s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.19s]
Computing alignments...  [31.102s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.04s]
Sorting trace points...  [1.207s]
Computing alignments...  [31.328s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.217s]
Computing alignments...  [31.432s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.201s]
Computing alignments...  [31.481s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.019s]
Computing alignments...  [31.665s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.073s]
Sorting trace points...  [0.924s]
Computing alignments...  [31.672s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.223s]
Computing alignments...  [31.379s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
 [513.032s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.474s]
Masking reference...  [32.132s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.21s]
Allocating buffers...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.472s]
Building query seed array...  [1.981s]
Computing hash join...  [5.118s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [68.35s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.775s]
Building query seed array...  [2.298s]
Computing hash join...  [5.167s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [46.815s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.536s]
Building query seed array...  [2.35s]
Computing hash join...  [5.182s]
Masking low complexity seeds...  [0.256s]
Searching alignments...  [40.552s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.285s]
Building query seed array...  [1.953s]
Computing hash join...  [5.158s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [37.36s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.198s]
Building query seed array...  [1.747s]
Computing hash join...  [4.957s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [37.356s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.963s]
Building query seed array...  [2.072s]
Computing hash join...  [4.841s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [30.261s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.534s]
Building query seed array...  [2.158s]
Computing hash join...  [5.001s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [31.577s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.132s]
Building query seed array...  [1.741s]
Computing hash join...  [4.98s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [27.008s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.128s]
Clearing query masking...  [1.515s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.043s]
Sorting trace points...  [1.22s]
Computing alignments...  [29.735s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.065s]
Sorting trace points...  [0.919s]
Computing alignments...  [29.823s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.066s]
Sorting trace points...  [0.871s]
Computing alignments...  [29.827s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.102s]
Sorting trace points...  [1.052s]
Computing alignments...  [29.205s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.036s]
Sorting trace points...  [1.091s]
Computing alignments...  [29.429s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.042s]
Sorting trace points...  [0.828s]
Computing alignments...  [28.984s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.002s]
Computing alignments...  [29.278s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.064s]
Computing alignments...  [28.677s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.175s]
Computing alignments...  [29.822s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.085s]
Sorting trace points...  [1.146s]
Computing alignments...  [30.859s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.175s]
Computing alignments...  [31.094s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.04s]
Sorting trace points...  [1.223s]
Computing alignments...  [31.196s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.055s]
Computing alignments...  [31.141s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.226s]
Computing alignments...  [31.308s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.229s]
Computing alignments...  [31.282s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.197s]
Computing alignments...  [31.147s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
 [507.547s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [29.501s]
Masking reference...  [32.08s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.523s]
Allocating buffers...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.377s]
Building query seed array...  [1.964s]
Computing hash join...  [5.229s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [71.375s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.394s]
Building query seed array...  [2.29s]
Computing hash join...  [5.181s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [47.649s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.958s]
Building query seed array...  [2.392s]
Computing hash join...  [5.138s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [42.953s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.922s]
Building query seed array...  [1.987s]
Computing hash join...  [5.17s]
Masking low complexity seeds...  [0.263s]
Searching alignments...  [37.043s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.055s]
Building query seed array...  [1.804s]
Computing hash join...  [4.998s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [38.675s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.328s]
Building query seed array...  [2.04s]
Computing hash join...  [4.914s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [31.175s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.15s]
Building query seed array...  [2.229s]
Computing hash join...  [4.987s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [33.417s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.93s]
Building query seed array...  [1.786s]
Computing hash join...  [4.978s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [28.042s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.127s]
Clearing query masking...  [1.57s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.171s]
Sorting trace points...  [1.117s]
Computing alignments...  [30.132s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.183s]
Computing alignments...  [30.461s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.073s]
Sorting trace points...  [0.901s]
Computing alignments...  [30.358s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.158s]
Computing alignments...  [29.761s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.093s]
Computing alignments...  [29.781s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.118s]
Computing alignments...  [29.389s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.884s]
Sorting trace points...  [1.158s]
Computing alignments...  [29.568s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.052s]
Sorting trace points...  [0.825s]
Computing alignments...  [28.966s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.876s]
Sorting trace points...  [1.189s]
Computing alignments...  [30.164s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.04s]
Sorting trace points...  [1.147s]
Computing alignments...  [31.194s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.166s]
Computing alignments...  [31.421s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.193s]
Computing alignments...  [31.471s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.191s]
Computing alignments...  [31.379s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.18s]
Computing alignments...  [31.546s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.207s]
Computing alignments...  [31.575s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [0.94s]
Computing alignments...  [31.314s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [515.31s]
Deallocating reference...  [0.063s]
Loading reference sequences...  [29.477s]
Masking reference...  [32.159s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.329s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.285s]
Building query seed array...  [2.005s]
Computing hash join...  [5.246s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [72.731s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.447s]
Building query seed array...  [2.348s]
Computing hash join...  [5.132s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [47.802s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.765s]
Building query seed array...  [2.462s]
Computing hash join...  [5.15s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [42.808s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.982s]
Building query seed array...  [1.967s]
Computing hash join...  [5.168s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [37.167s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.148s]
Building query seed array...  [1.798s]
Computing hash join...  [4.951s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [38.356s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.295s]
Building query seed array...  [2.102s]
Computing hash join...  [4.81s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [30.557s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.589s]
Building query seed array...  [2.227s]
Computing hash join...  [4.91s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [33.722s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.898s]
Building query seed array...  [1.771s]
Computing hash join...  [4.945s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [27.928s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.13s]
Clearing query masking...  [1.507s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.086s]
Sorting trace points...  [1.198s]
Computing alignments...  [30.109s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.087s]
Sorting trace points...  [1.111s]
Computing alignments...  [30.222s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.092s]
Sorting trace points...  [1.119s]
Computing alignments...  [30.137s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.087s]
Sorting trace points...  [1.168s]
Computing alignments...  [29.628s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.122s]
Computing alignments...  [29.687s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.065s]
Sorting trace points...  [0.84s]
Computing alignments...  [29.307s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.119s]
Computing alignments...  [29.533s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.086s]
Computing alignments...  [28.991s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.127s]
Computing alignments...  [30.042s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.094s]
Computing alignments...  [31.116s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.229s]
Computing alignments...  [31.286s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.246s]
Computing alignments...  [31.427s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.047s]
Sorting trace points...  [0.963s]
Computing alignments...  [31.371s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.084s]
Sorting trace points...  [0.926s]
Computing alignments...  [31.563s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.064s]
Computing alignments...  [31.543s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.229s]
Computing alignments...  [31.306s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [512.995s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [31.792s]
Masking reference...  [30.837s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.539s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.252s]
Building query seed array...  [1.984s]
Computing hash join...  [5.166s]
Masking low complexity seeds...  [0.259s]
Searching alignments...  [71.406s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.098s]
Building query seed array...  [2.279s]
Computing hash join...  [5.126s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [47.879s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.039s]
Building query seed array...  [2.361s]
Computing hash join...  [5.156s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [40.045s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.659s]
Building query seed array...  [1.927s]
Computing hash join...  [5.199s]
Masking low complexity seeds...  [0.269s]
Searching alignments...  [36.998s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.937s]
Building query seed array...  [1.783s]
Computing hash join...  [4.922s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [39.632s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.299s]
Building query seed array...  [2.057s]
Computing hash join...  [4.9s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [29.973s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.893s]
Building query seed array...  [2.131s]
Computing hash join...  [4.954s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [33.125s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.019s]
Building query seed array...  [1.782s]
Computing hash join...  [5s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [28.667s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.535s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.076s]
Sorting trace points...  [1.221s]
Computing alignments...  [29.987s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.147s]
Computing alignments...  [30.245s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.106s]
Computing alignments...  [30.171s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.098s]
Computing alignments...  [29.678s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.062s]
Sorting trace points...  [0.905s]
Computing alignments...  [29.711s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.117s]
Computing alignments...  [29.947s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.1s]
Computing alignments...  [29.488s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.095s]
Computing alignments...  [29.036s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.173s]
Computing alignments...  [30.061s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.002s]
Sorting trace points...  [1.209s]
Computing alignments...  [31.136s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.219s]
Computing alignments...  [31.303s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.238s]
Computing alignments...  [31.368s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.246s]
Computing alignments...  [31.36s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.686s]
Sorting trace points...  [1.198s]
Computing alignments...  [31.484s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.208s]
Computing alignments...  [31.574s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.131s]
Computing alignments...  [31.271s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [514.067s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.741s]
Masking reference...  [30.842s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.741s]
Allocating buffers...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.52s]
Building query seed array...  [1.938s]
Computing hash join...  [5.212s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [71.915s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.576s]
Building query seed array...  [2.241s]
Computing hash join...  [5.112s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [45.356s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.369s]
Building query seed array...  [2.413s]
Computing hash join...  [5.169s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [41.622s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.1s]
Building query seed array...  [1.906s]
Computing hash join...  [5.163s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [36.41s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.598s]
Building query seed array...  [1.794s]
Computing hash join...  [4.927s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [39.33s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.338s]
Building query seed array...  [2.074s]
Computing hash join...  [4.928s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [30.075s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.156s]
Building query seed array...  [2.196s]
Computing hash join...  [4.926s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [32.984s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.872s]
Building query seed array...  [1.732s]
Computing hash join...  [4.93s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [29.172s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.133s]
Clearing query masking...  [1.552s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.119s]
Sorting trace points...  [1.222s]
Computing alignments...  [30.096s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.159s]
Computing alignments...  [30.295s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.066s]
Sorting trace points...  [0.893s]
Computing alignments...  [30.267s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.128s]
Computing alignments...  [29.684s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.131s]
Computing alignments...  [29.778s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.109s]
Computing alignments...  [29.268s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.054s]
Sorting trace points...  [0.998s]
Computing alignments...  [29.58s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.119s]
Computing alignments...  [29.091s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.025s]
Computing alignments...  [29.991s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.002s]
Sorting trace points...  [1.169s]
Computing alignments...  [31.114s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.18s]
Computing alignments...  [31.344s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.184s]
Computing alignments...  [31.341s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.013s]
Computing alignments...  [31.363s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.087s]
Computing alignments...  [31.499s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.227s]
Computing alignments...  [31.578s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
Sorting trace points...  [1.214s]
Computing alignments...  [31.242s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
 [512.683s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [32.661s]
Masking reference...  [31.731s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [31.879s]
Allocating buffers...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.286s]
Building query seed array...  [1.97s]
Computing hash join...  [5.201s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [70.769s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.8s]
Building query seed array...  [2.288s]
Computing hash join...  [5.168s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [45.439s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.536s]
Building query seed array...  [2.423s]
Computing hash join...  [5.112s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [40.129s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.013s]
Building query seed array...  [1.919s]
Computing hash join...  [5.175s]
Masking low complexity seeds...  [0.259s]
Searching alignments...  [36.714s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.025s]
Building query seed array...  [1.752s]
Computing hash join...  [4.859s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [38.656s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.431s]
Building query seed array...  [2.057s]
Computing hash join...  [4.895s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [29.859s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.535s]
Building query seed array...  [2.226s]
Computing hash join...  [4.942s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [32.813s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.648s]
Building query seed array...  [1.752s]
Computing hash join...  [5.007s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [28.55s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.499s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.296s]
Sorting trace points...  [1.202s]
Computing alignments...  [30.314s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.176s]
Computing alignments...  [30.633s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.14s]
Computing alignments...  [30.391s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.484s]
Sorting trace points...  [0.889s]
Computing alignments...  [29.872s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.095s]
Computing alignments...  [30.008s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.243s]
Sorting trace points...  [1.147s]
Computing alignments...  [29.386s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.124s]
Computing alignments...  [29.67s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.019s]
Computing alignments...  [29.638s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.154s]
Computing alignments...  [30.172s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.163s]
Computing alignments...  [31.226s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.197s]
Computing alignments...  [31.841s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.042s]
Computing alignments...  [31.37s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.196s]
Computing alignments...  [31.334s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.047s]
Sorting trace points...  [0.943s]
Computing alignments...  [31.501s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.171s]
Computing alignments...  [31.543s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.202s]
Computing alignments...  [31.359s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
 [516.16s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [33.518s]
Masking reference...  [31.91s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.407s]
Allocating buffers...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.755s]
Building query seed array...  [1.947s]
Computing hash join...  [5.096s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [72.033s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.348s]
Building query seed array...  [2.31s]
Computing hash join...  [5.163s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [46.512s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.369s]
Building query seed array...  [2.321s]
Computing hash join...  [5.113s]
Masking low complexity seeds...  [0.256s]
Searching alignments...  [42.127s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.137s]
Building query seed array...  [1.976s]
Computing hash join...  [5.181s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [38.726s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.024s]
Building query seed array...  [1.825s]
Computing hash join...  [4.924s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [38.086s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.754s]
Building query seed array...  [2.076s]
Computing hash join...  [4.944s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [30.129s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.206s]
Building query seed array...  [2.159s]
Computing hash join...  [4.922s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [34.274s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.941s]
Building query seed array...  [1.734s]
Computing hash join...  [5.066s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [28.037s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.518s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.124s]
Sorting trace points...  [1.18s]
Computing alignments...  [29.954s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.128s]
Computing alignments...  [30.201s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.141s]
Computing alignments...  [30.227s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.08s]
Sorting trace points...  [0.911s]
Computing alignments...  [29.632s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.127s]
Computing alignments...  [29.676s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.028s]
Computing alignments...  [29.348s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.123s]
Computing alignments...  [29.471s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.05s]
Sorting trace points...  [0.88s]
Computing alignments...  [29.009s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.134s]
Sorting trace points...  [1.136s]
Computing alignments...  [30.122s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.172s]
Computing alignments...  [31.11s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.219s]
Computing alignments...  [31.454s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.092s]
Sorting trace points...  [1.182s]
Computing alignments...  [31.538s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.18s]
Computing alignments...  [31.505s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.218s]
Computing alignments...  [31.483s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.057s]
Sorting trace points...  [0.945s]
Computing alignments...  [31.611s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.224s]
Computing alignments...  [31.246s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [512.895s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [29.741s]
Masking reference...  [32.151s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.499s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [9.952s]
Building query seed array...  [1.907s]
Computing hash join...  [5.188s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [71.472s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.08s]
Building query seed array...  [2.25s]
Computing hash join...  [5.067s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [46.322s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.621s]
Building query seed array...  [2.434s]
Computing hash join...  [5.061s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [42.632s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.189s]
Building query seed array...  [1.914s]
Computing hash join...  [5.206s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [37.957s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.283s]
Building query seed array...  [1.749s]
Computing hash join...  [5.07s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [40.725s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.214s]
Building query seed array...  [2.046s]
Computing hash join...  [4.968s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [30.266s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.418s]
Building query seed array...  [2.191s]
Computing hash join...  [4.981s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [33.138s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.86s]
Building query seed array...  [1.797s]
Computing hash join...  [4.909s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [28.099s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.122s]
Clearing query masking...  [1.503s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.095s]
Sorting trace points...  [1.173s]
Computing alignments...  [30.148s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.134s]
Computing alignments...  [30.386s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.164s]
Computing alignments...  [30.34s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.052s]
Sorting trace points...  [0.89s]
Computing alignments...  [29.712s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.088s]
Sorting trace points...  [0.906s]
Computing alignments...  [29.745s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.089s]
Computing alignments...  [29.324s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.052s]
Sorting trace points...  [0.847s]
Computing alignments...  [29.668s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.13s]
Computing alignments...  [29.173s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.088s]
Sorting trace points...  [1.159s]
Computing alignments...  [30.164s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.002s]
Sorting trace points...  [1.062s]
Computing alignments...  [31.201s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.032s]
Sorting trace points...  [1.197s]
Computing alignments...  [31.472s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.024s]
Computing alignments...  [31.555s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.195s]
Computing alignments...  [31.551s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.039s]
Sorting trace points...  [1.236s]
Computing alignments...  [31.699s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.186s]
Computing alignments...  [31.568s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.027s]
Computing alignments...  [31.442s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [513.82s]
Deallocating reference...  [0.063s]
Loading reference sequences...  [23.722s]
Masking reference...  [26.088s]
Initializing dictionary...  [0.064s]
Initializing temporary storage...  [0.005s]
Building reference histograms...  [26.606s]
Allocating buffers...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.498s]
Building query seed array...  [1.925s]
Computing hash join...  [4.322s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [59.305s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [9.811s]
Building query seed array...  [2.262s]
Computing hash join...  [4.289s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [37.297s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [11.095s]
Building query seed array...  [2.411s]
Computing hash join...  [4.266s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [32.778s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [8.294s]
Building query seed array...  [2.02s]
Computing hash join...  [4.243s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [31.898s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [8.095s]
Building query seed array...  [1.846s]
Computing hash join...  [4.171s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [31.625s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [10.01s]
Building query seed array...  [2.096s]
Computing hash join...  [4.107s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [24.696s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [10.718s]
Building query seed array...  [2.157s]
Computing hash join...  [4.312s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [27.064s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [8.224s]
Building query seed array...  [1.773s]
Computing hash join...  [4.161s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [24.166s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.102s]
Clearing query masking...  [1.476s]
Opening temporary output file...  [0.014s]
Computing alignments... Loading trace points...  [10.328s]
Sorting trace points...  [1.907s]
Computing alignments...  [48.146s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.106s]
Sorting trace points...  [1.899s]
Computing alignments...  [47.774s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.116s]
Sorting trace points...  [1.83s]
Computing alignments...  [47.168s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.772s]
Computing alignments...  [46.64s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.183s]
Sorting trace points...  [1.588s]
Computing alignments...  [48.66s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.145s]
Sorting trace points...  [1.749s]
Computing alignments...  [49.999s]
Deallocating buffers...  [0.031s]
Loading trace points...  [0.132s]
Sorting trace points...  [1.614s]
Computing alignments...  [50.232s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
Sorting trace points...  [1.772s]
Computing alignments...  [49.881s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
 [413.969s]
Deallocating reference...  [0.054s]
Loading reference sequences...  [0.096s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [1800.9s]
 [1800.9s]
Deallocating queries...  [0.061s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [4.121s]
 [5.338s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 16950.6s
Reported 2222211374 pairwise alignments, 2222211374 HSPs.
13000178 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E14_R2.fastp-trim.20230215.fq.gz complete: E14_R2.blastx.meganized.daa

Now MEGANizing E14_R2.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: E14_R2.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 80% 100% (274.6s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (3.2s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (4,170.9s)
Total reads:       13,000,178
With hits:          13,000,178 
Alignments:      2,213,363,180
Assig. Taxonomy:    11,755,160
Assig. SEED:           121,994
Assig. EGGNOG:          65,559
Assig. GTDB:           398,814
Assig. EC:           1,962,713
Assig. INTERPRO2GO:  1,157,215
MinSupport set to: 6500
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.4s)
Min-supp. changes:       4,429
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (11.5s)
Min-supp. changes:       3,545
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (27.0s)
Binning reads Syncing
100% (0.4s)
Class. Taxonomy:            82
Class. SEED:               529
Class. EGGNOG:           1,858
Class. GTDB:                22
Class. EC:               2,445
Class. INTERPRO2GO:      7,965
Total time:  4,497s
Peak memory: 34.3 of 195.3G
MEGANization of E14_R2.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E15_R1.fastp-trim.20230215.fq.gz...
0994e9007e17e6d0d8666806d2bf763b  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E15_R1.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E15_R1.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.323s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.714s]
Opening the output file...  [0s]
Loading query sequences...  [71.653s]
Masking queries...  [18.392s]
Algorithm: Double-indexed
Building query histograms...  [17.144s]
Loading reference sequences...  [30.052s]
Masking reference...  [31.973s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.57s]
Allocating buffers...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.332s]
Building query seed array...  [2.056s]
Computing hash join...  [5.329s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [72.316s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.14s]
Building query seed array...  [2.352s]
Computing hash join...  [5.226s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [47.229s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.55s]
Building query seed array...  [2.563s]
Computing hash join...  [5.168s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [41.81s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.347s]
Building query seed array...  [2.005s]
Computing hash join...  [5.203s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [38.889s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.32s]
Building query seed array...  [1.828s]
Computing hash join...  [4.917s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [37.485s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.111s]
Building query seed array...  [2.112s]
Computing hash join...  [4.913s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [29.718s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.308s]
Building query seed array...  [2.302s]
Computing hash join...  [4.935s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [32.305s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.172s]
Building query seed array...  [1.855s]
Computing hash join...  [5.045s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [28.839s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.137s]
Clearing query masking...  [1.618s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.119s]
Sorting trace points...  [1.17s]
Computing alignments...  [29.742s]
Deallocating buffers...  [0.016s]
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Sorting trace points...  [1.062s]
Computing alignments...  [29.646s]
Deallocating buffers...  [0.014s]
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Sorting trace points...  [1.03s]
Computing alignments...  [29.965s]
Deallocating buffers...  [0.014s]
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Sorting trace points...  [1.041s]
Computing alignments...  [29.477s]
Deallocating buffers...  [0.016s]
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Sorting trace points...  [1.077s]
Computing alignments...  [29.441s]
Deallocating buffers...  [0.013s]
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Sorting trace points...  [1.11s]
Computing alignments...  [29.189s]
Deallocating buffers...  [0.016s]
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Sorting trace points...  [0.846s]
Computing alignments...  [29.155s]
Deallocating buffers...  [0.014s]
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Sorting trace points...  [1.102s]
Computing alignments...  [29.301s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.152s]
Computing alignments...  [30.539s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.16s]
Computing alignments...  [30.887s]
Deallocating buffers...  [0.017s]
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Sorting trace points...  [1.183s]
Computing alignments...  [30.944s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.095s]
Computing alignments...  [30.616s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.946s]
Sorting trace points...  [1.205s]
Computing alignments...  [30.743s]
Deallocating buffers...  [0.017s]
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Sorting trace points...  [1.025s]
Computing alignments...  [30.94s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.187s]
Computing alignments...  [30.882s]
Deallocating buffers...  [0.023s]
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Sorting trace points...  [1.186s]
Computing alignments...  [30.587s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [507.783s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.816s]
Masking reference...  [30.883s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.464s]
Allocating buffers...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.12s]
Building query seed array...  [2.049s]
Computing hash join...  [5.199s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [69.549s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.533s]
Building query seed array...  [2.435s]
Computing hash join...  [5.182s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [46.367s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.46s]
Building query seed array...  [2.564s]
Computing hash join...  [5.06s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [39.893s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.071s]
Building query seed array...  [2.056s]
Computing hash join...  [5.15s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [36.815s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.963s]
Building query seed array...  [1.96s]
Computing hash join...  [4.928s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [37.057s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.705s]
Building query seed array...  [2.149s]
Computing hash join...  [4.974s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [29.236s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.473s]
Building query seed array...  [2.273s]
Computing hash join...  [4.906s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [31.759s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.952s]
Building query seed array...  [1.833s]
Computing hash join...  [4.986s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [27.892s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.13s]
Clearing query masking...  [1.566s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.02s]
Sorting trace points...  [1.19s]
Computing alignments...  [29.519s]
Deallocating buffers...  [0.015s]
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Sorting trace points...  [1.014s]
Computing alignments...  [29.425s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.05s]
Sorting trace points...  [0.954s]
Computing alignments...  [29.781s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.151s]
Computing alignments...  [29.268s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.088s]
Computing alignments...  [29.28s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.103s]
Sorting trace points...  [0.942s]
Computing alignments...  [28.972s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.129s]
Computing alignments...  [29.075s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.065s]
Computing alignments...  [29.14s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.167s]
Computing alignments...  [30.376s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.163s]
Computing alignments...  [30.716s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.092s]
Sorting trace points...  [1.197s]
Computing alignments...  [30.971s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.174s]
Computing alignments...  [30.507s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.168s]
Computing alignments...  [30.535s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.155s]
Computing alignments...  [30.84s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.203s]
Computing alignments...  [30.582s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.124s]
Computing alignments...  [30.384s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [504.6s]
Deallocating reference...  [0.457s]
Loading reference sequences...  [29.618s]
Masking reference...  [31.056s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.868s]
Allocating buffers...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.222s]
Building query seed array...  [2.154s]
Computing hash join...  [5.205s]
Masking low complexity seeds...  [0.254s]
Searching alignments...  [73.035s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.406s]
Building query seed array...  [2.448s]
Computing hash join...  [5.234s]
Masking low complexity seeds...  [0.249s]
Searching alignments...  [47.058s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.535s]
Building query seed array...  [2.548s]
Computing hash join...  [5.104s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [43.219s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.118s]
Building query seed array...  [2.033s]
Computing hash join...  [5.163s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [37.778s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.019s]
Building query seed array...  [1.904s]
Computing hash join...  [4.979s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [36.659s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.151s]
Building query seed array...  [2.195s]
Computing hash join...  [4.971s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [29.33s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.174s]
Building query seed array...  [2.28s]
Computing hash join...  [4.918s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [32.125s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.853s]
Building query seed array...  [1.883s]
Computing hash join...  [4.937s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [28.779s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.136s]
Clearing query masking...  [1.496s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.18s]
Sorting trace points...  [1.067s]
Computing alignments...  [29.56s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.064s]
Sorting trace points...  [0.98s]
Computing alignments...  [29.454s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.06s]
Sorting trace points...  [0.882s]
Computing alignments...  [29.79s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.139s]
Computing alignments...  [29.276s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.104s]
Computing alignments...  [29.321s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.083s]
Computing alignments...  [29.094s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.09s]
Computing alignments...  [29.125s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.131s]
Computing alignments...  [29.243s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.038s]
Sorting trace points...  [1.104s]
Computing alignments...  [30.35s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.202s]
Computing alignments...  [30.765s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.211s]
Computing alignments...  [31.484s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.198s]
Computing alignments...  [30.464s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.185s]
Computing alignments...  [30.604s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.175s]
Computing alignments...  [30.912s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.197s]
Computing alignments...  [30.691s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.012s]
Computing alignments...  [30.397s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [505.511s]
Deallocating reference...  [0.063s]
Loading reference sequences...  [29.65s]
Masking reference...  [32.226s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [31.68s]
Allocating buffers...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.255s]
Building query seed array...  [2.131s]
Computing hash join...  [5.179s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [70.55s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.567s]
Building query seed array...  [2.41s]
Computing hash join...  [5.187s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [46.226s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.088s]
Building query seed array...  [2.613s]
Computing hash join...  [5.151s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [40.697s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.938s]
Building query seed array...  [2.06s]
Computing hash join...  [5.106s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [38.374s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.882s]
Building query seed array...  [1.905s]
Computing hash join...  [4.958s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [36.177s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.436s]
Building query seed array...  [2.177s]
Computing hash join...  [4.902s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [29.546s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.185s]
Building query seed array...  [2.323s]
Computing hash join...  [4.964s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [32.042s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.168s]
Building query seed array...  [1.81s]
Computing hash join...  [5.018s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [28.388s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.537s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.641s]
Sorting trace points...  [1.197s]
Computing alignments...  [29.719s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.072s]
Sorting trace points...  [0.997s]
Computing alignments...  [29.616s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.049s]
Sorting trace points...  [0.83s]
Computing alignments...  [29.816s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.125s]
Computing alignments...  [29.329s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [0.972s]
Computing alignments...  [29.37s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.08s]
Computing alignments...  [29.032s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.127s]
Computing alignments...  [29.122s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.15s]
Computing alignments...  [29.187s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.187s]
Computing alignments...  [30.459s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.09s]
Computing alignments...  [30.749s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.165s]
Computing alignments...  [31.456s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.054s]
Sorting trace points...  [0.921s]
Computing alignments...  [30.495s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.173s]
Computing alignments...  [30.626s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.163s]
Computing alignments...  [30.921s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.161s]
Computing alignments...  [30.706s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.151s]
Computing alignments...  [30.564s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
 [506.357s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [29.76s]
Masking reference...  [30.837s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.277s]
Allocating buffers...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.293s]
Building query seed array...  [2.122s]
Computing hash join...  [5.239s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [72.132s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.423s]
Building query seed array...  [2.346s]
Computing hash join...  [5.14s]
Masking low complexity seeds...  [0.249s]
Searching alignments...  [44.812s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.564s]
Building query seed array...  [2.578s]
Computing hash join...  [5.099s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [41.763s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.663s]
Building query seed array...  [2.032s]
Computing hash join...  [5.105s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [35.877s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.966s]
Building query seed array...  [1.87s]
Computing hash join...  [4.941s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [35.795s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.934s]
Building query seed array...  [2.175s]
Computing hash join...  [4.994s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [29.088s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.472s]
Building query seed array...  [2.324s]
Computing hash join...  [4.981s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [31.641s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.987s]
Building query seed array...  [1.952s]
Computing hash join...  [4.949s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [27.912s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.14s]
Clearing query masking...  [1.632s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.048s]
Sorting trace points...  [1.178s]
Computing alignments...  [29.52s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.106s]
Computing alignments...  [29.475s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.121s]
Computing alignments...  [29.757s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.122s]
Computing alignments...  [29.358s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.084s]
Computing alignments...  [29.205s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.834s]
Sorting trace points...  [1.112s]
Computing alignments...  [28.96s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.092s]
Computing alignments...  [28.989s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.591s]
Sorting trace points...  [0.878s]
Computing alignments...  [29.216s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.176s]
Computing alignments...  [30.357s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.186s]
Computing alignments...  [30.606s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.219s]
Computing alignments...  [30.774s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.118s]
Computing alignments...  [30.444s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.093s]
Sorting trace points...  [1.125s]
Computing alignments...  [30.571s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.183s]
Computing alignments...  [30.889s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.183s]
Computing alignments...  [30.785s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.161s]
Computing alignments...  [30.559s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [506.057s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [31.9s]
Masking reference...  [31.91s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [31.704s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.573s]
Building query seed array...  [2.085s]
Computing hash join...  [5.205s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [70.035s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.222s]
Building query seed array...  [2.441s]
Computing hash join...  [5.154s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [44.213s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.337s]
Building query seed array...  [2.582s]
Computing hash join...  [5.095s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [40.912s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.958s]
Building query seed array...  [2.08s]
Computing hash join...  [5.251s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [36.026s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.654s]
Building query seed array...  [1.822s]
Computing hash join...  [4.922s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [35.788s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.466s]
Building query seed array...  [2.141s]
Computing hash join...  [4.949s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [29.014s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.475s]
Building query seed array...  [2.222s]
Computing hash join...  [5.032s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [32.281s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.3s]
Building query seed array...  [1.888s]
Computing hash join...  [4.984s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [27.087s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.121s]
Clearing query masking...  [1.489s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.013s]
Sorting trace points...  [1.211s]
Computing alignments...  [29.554s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.093s]
Computing alignments...  [29.42s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.052s]
Sorting trace points...  [0.982s]
Computing alignments...  [29.56s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.038s]
Sorting trace points...  [1.142s]
Computing alignments...  [29.138s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.116s]
Computing alignments...  [29.147s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.067s]
Sorting trace points...  [0.841s]
Computing alignments...  [28.988s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.038s]
Sorting trace points...  [0.954s]
Computing alignments...  [28.972s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.123s]
Computing alignments...  [29.163s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.133s]
Computing alignments...  [30.268s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.189s]
Computing alignments...  [30.576s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.152s]
Computing alignments...  [30.662s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.151s]
Computing alignments...  [30.36s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.003s]
Computing alignments...  [30.525s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.181s]
Computing alignments...  [30.711s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.191s]
Computing alignments...  [30.548s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.134s]
Computing alignments...  [30.408s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
 [502.683s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [31.584s]
Masking reference...  [32.065s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.25s]
Allocating buffers...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.249s]
Building query seed array...  [2.023s]
Computing hash join...  [5.142s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [73.265s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.095s]
Building query seed array...  [2.368s]
Computing hash join...  [5.128s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [46.009s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.266s]
Building query seed array...  [2.487s]
Computing hash join...  [5.105s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [40.544s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.194s]
Building query seed array...  [1.99s]
Computing hash join...  [5.028s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [36.84s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.155s]
Building query seed array...  [1.91s]
Computing hash join...  [5.068s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [36.895s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.983s]
Building query seed array...  [2.226s]
Computing hash join...  [5.008s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [30.097s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.895s]
Building query seed array...  [2.285s]
Computing hash join...  [4.955s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [32.118s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.954s]
Building query seed array...  [1.852s]
Computing hash join...  [4.951s]
Masking low complexity seeds...  [0.249s]
Searching alignments...  [30.186s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.134s]
Clearing query masking...  [1.54s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.029s]
Sorting trace points...  [1.166s]
Computing alignments...  [29.62s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.106s]
Sorting trace points...  [1.094s]
Computing alignments...  [29.538s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.152s]
Computing alignments...  [29.704s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.13s]
Computing alignments...  [29.346s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [0.998s]
Computing alignments...  [29.301s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.111s]
Computing alignments...  [29.051s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.042s]
Sorting trace points...  [1.057s]
Computing alignments...  [29.111s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.143s]
Computing alignments...  [29.226s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.152s]
Computing alignments...  [30.452s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.159s]
Computing alignments...  [30.723s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.16s]
Computing alignments...  [31.333s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.154s]
Computing alignments...  [30.564s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.183s]
Computing alignments...  [30.627s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.363s]
Sorting trace points...  [1.154s]
Computing alignments...  [30.945s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.044s]
Sorting trace points...  [0.944s]
Computing alignments...  [30.843s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.186s]
Computing alignments...  [30.509s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [506.328s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [29.722s]
Masking reference...  [30.851s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.483s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.523s]
Building query seed array...  [2.079s]
Computing hash join...  [5.195s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [71.632s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.14s]
Building query seed array...  [2.397s]
Computing hash join...  [5.2s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [46.718s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.605s]
Building query seed array...  [2.507s]
Computing hash join...  [5.128s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [40.702s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.845s]
Building query seed array...  [2.065s]
Computing hash join...  [5.153s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [36.472s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.13s]
Building query seed array...  [1.899s]
Computing hash join...  [4.929s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [37.847s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.876s]
Building query seed array...  [2.214s]
Computing hash join...  [4.953s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [29.955s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.59s]
Building query seed array...  [2.307s]
Computing hash join...  [5.001s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [33.16s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.059s]
Building query seed array...  [1.864s]
Computing hash join...  [4.93s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [28.279s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.469s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [5.986s]
Sorting trace points...  [1.185s]
Computing alignments...  [29.626s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.068s]
Sorting trace points...  [0.993s]
Computing alignments...  [29.535s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.157s]
Computing alignments...  [29.904s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.129s]
Computing alignments...  [29.761s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.06s]
Computing alignments...  [29.277s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.073s]
Computing alignments...  [29.016s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.143s]
Computing alignments...  [29.044s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.126s]
Computing alignments...  [29.279s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.213s]
Computing alignments...  [30.429s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.045s]
Sorting trace points...  [0.905s]
Computing alignments...  [30.81s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.206s]
Computing alignments...  [31.06s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.036s]
Sorting trace points...  [1.121s]
Computing alignments...  [30.552s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.131s]
Computing alignments...  [30.626s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.182s]
Computing alignments...  [30.968s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.058s]
Sorting trace points...  [0.951s]
Computing alignments...  [30.804s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [0.955s]
Computing alignments...  [30.476s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [505.752s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [34.348s]
Masking reference...  [31.038s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.689s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.308s]
Building query seed array...  [2.028s]
Computing hash join...  [5.165s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [72.234s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.141s]
Building query seed array...  [2.416s]
Computing hash join...  [5.119s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [45.885s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.443s]
Building query seed array...  [2.54s]
Computing hash join...  [5.163s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [40.996s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.023s]
Building query seed array...  [2.01s]
Computing hash join...  [5.1s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [35.76s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.703s]
Building query seed array...  [1.899s]
Computing hash join...  [4.983s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [36.661s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.143s]
Building query seed array...  [2.128s]
Computing hash join...  [4.952s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [29.788s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.187s]
Building query seed array...  [2.312s]
Computing hash join...  [4.991s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [32.617s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.757s]
Building query seed array...  [1.821s]
Computing hash join...  [4.913s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [27.681s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.122s]
Clearing query masking...  [1.542s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.014s]
Sorting trace points...  [1.199s]
Computing alignments...  [29.564s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.072s]
Sorting trace points...  [0.889s]
Computing alignments...  [29.573s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.143s]
Computing alignments...  [29.761s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.119s]
Computing alignments...  [29.365s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.148s]
Computing alignments...  [29.306s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.071s]
Computing alignments...  [29.039s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.095s]
Computing alignments...  [29.032s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.091s]
Sorting trace points...  [1.087s]
Computing alignments...  [29.274s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.155s]
Computing alignments...  [30.405s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.185s]
Computing alignments...  [30.725s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.05s]
Computing alignments...  [31.393s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.164s]
Computing alignments...  [30.569s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.188s]
Computing alignments...  [30.635s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.162s]
Computing alignments...  [30.883s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.052s]
Sorting trace points...  [0.988s]
Computing alignments...  [30.726s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.192s]
Computing alignments...  [30.451s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
 [505.687s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.699s]
Masking reference...  [30.832s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.654s]
Allocating buffers...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.532s]
Building query seed array...  [2.033s]
Computing hash join...  [5.088s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [73.211s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.503s]
Building query seed array...  [2.332s]
Computing hash join...  [5.131s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [47.288s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [12.962s]
Building query seed array...  [2.45s]
Computing hash join...  [5.084s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [40.612s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.344s]
Building query seed array...  [2.055s]
Computing hash join...  [5.196s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [37.147s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.235s]
Building query seed array...  [1.849s]
Computing hash join...  [5.007s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [37.033s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.63s]
Building query seed array...  [2.13s]
Computing hash join...  [4.936s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [30.313s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.948s]
Building query seed array...  [2.403s]
Computing hash join...  [4.921s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [33.177s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.936s]
Building query seed array...  [1.871s]
Computing hash join...  [5.041s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [27.654s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.452s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [5.885s]
Sorting trace points...  [1.184s]
Computing alignments...  [29.717s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.065s]
Sorting trace points...  [0.995s]
Computing alignments...  [29.609s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.019s]
Computing alignments...  [29.879s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.126s]
Computing alignments...  [29.364s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.091s]
Sorting trace points...  [0.967s]
Computing alignments...  [29.288s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.11s]
Computing alignments...  [29.01s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.116s]
Computing alignments...  [29.019s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.15s]
Computing alignments...  [29.209s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.077s]
Sorting trace points...  [0.999s]
Computing alignments...  [30.423s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.041s]
Sorting trace points...  [0.983s]
Computing alignments...  [30.797s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.144s]
Computing alignments...  [31.262s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.151s]
Computing alignments...  [30.48s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.147s]
Computing alignments...  [30.515s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.183s]
Computing alignments...  [30.864s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.132s]
Computing alignments...  [30.768s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
Sorting trace points...  [1.148s]
Computing alignments...  [30.428s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
 [505.278s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [29.915s]
Masking reference...  [32.134s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.096s]
Allocating buffers...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [9.872s]
Building query seed array...  [2.094s]
Computing hash join...  [5.194s]
Masking low complexity seeds...  [0.25s]
Searching alignments...  [71.593s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.461s]
Building query seed array...  [2.384s]
Computing hash join...  [5.123s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [46.455s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.157s]
Building query seed array...  [2.604s]
Computing hash join...  [5.262s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [40.357s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.35s]
Building query seed array...  [2.012s]
Computing hash join...  [5.133s]
Masking low complexity seeds...  [0.251s]
Searching alignments...  [36.677s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.252s]
Building query seed array...  [1.886s]
Computing hash join...  [4.91s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [36.472s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.332s]
Building query seed array...  [2.106s]
Computing hash join...  [4.906s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [30.096s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.806s]
Building query seed array...  [2.344s]
Computing hash join...  [5.025s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [32.562s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.065s]
Building query seed array...  [1.897s]
Computing hash join...  [5.014s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [27.873s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.136s]
Clearing query masking...  [1.541s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.033s]
Sorting trace points...  [1.143s]
Computing alignments...  [29.514s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.076s]
Computing alignments...  [29.416s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.063s]
Sorting trace points...  [0.836s]
Computing alignments...  [29.694s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.102s]
Computing alignments...  [29.203s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.092s]
Computing alignments...  [29.303s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.095s]
Computing alignments...  [28.934s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.128s]
Computing alignments...  [28.961s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.088s]
Computing alignments...  [29.063s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.048s]
Sorting trace points...  [0.912s]
Computing alignments...  [30.275s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.146s]
Computing alignments...  [30.624s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.083s]
Sorting trace points...  [0.914s]
Computing alignments...  [31.251s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.003s]
Sorting trace points...  [1.173s]
Computing alignments...  [30.419s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.061s]
Sorting trace points...  [0.981s]
Computing alignments...  [30.55s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.163s]
Computing alignments...  [30.772s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.154s]
Sorting trace points...  [1.15s]
Computing alignments...  [30.614s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.148s]
Computing alignments...  [30.837s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [503.772s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [33.287s]
Masking reference...  [30.87s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.317s]
Allocating buffers...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.349s]
Building query seed array...  [2.032s]
Computing hash join...  [5.224s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [73.092s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.165s]
Building query seed array...  [2.36s]
Computing hash join...  [5.13s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [46.935s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.64s]
Building query seed array...  [2.506s]
Computing hash join...  [5.235s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [42.557s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.906s]
Building query seed array...  [2.142s]
Computing hash join...  [5.155s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [35.734s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.891s]
Building query seed array...  [1.863s]
Computing hash join...  [5.037s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [37.519s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.497s]
Building query seed array...  [2.124s]
Computing hash join...  [5.092s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [29.497s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.555s]
Building query seed array...  [2.281s]
Computing hash join...  [4.948s]
Masking low complexity seeds...  [0.252s]
Searching alignments...  [32.613s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.752s]
Building query seed array...  [1.836s]
Computing hash join...  [4.972s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [27.607s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.549s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.127s]
Sorting trace points...  [1.203s]
Computing alignments...  [29.692s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.101s]
Computing alignments...  [29.567s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.126s]
Computing alignments...  [29.85s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.101s]
Computing alignments...  [29.334s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.048s]
Computing alignments...  [29.345s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0s]
Sorting trace points...  [1.112s]
Computing alignments...  [29.04s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.063s]
Sorting trace points...  [0.891s]
Computing alignments...  [29.102s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.136s]
Computing alignments...  [29.256s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.198s]
Computing alignments...  [30.451s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.064s]
Sorting trace points...  [0.954s]
Computing alignments...  [30.785s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.004s]
Sorting trace points...  [1.181s]
Computing alignments...  [31.376s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.065s]
Sorting trace points...  [0.983s]
Computing alignments...  [30.555s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.186s]
Computing alignments...  [30.667s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.133s]
Computing alignments...  [30.937s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.076s]
Sorting trace points...  [0.893s]
Computing alignments...  [30.767s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [1.016s]
Computing alignments...  [30.532s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [505.751s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.842s]
Masking reference...  [32.102s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [31.818s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.483s]
Building query seed array...  [2.082s]
Computing hash join...  [5.208s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [74.732s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.524s]
Building query seed array...  [2.466s]
Computing hash join...  [5.214s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [46.389s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.655s]
Building query seed array...  [2.624s]
Computing hash join...  [5.121s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [42.525s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.162s]
Building query seed array...  [2.025s]
Computing hash join...  [5.169s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [36.979s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.831s]
Building query seed array...  [1.846s]
Computing hash join...  [5.038s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [36.266s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.098s]
Building query seed array...  [2.231s]
Computing hash join...  [4.853s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [30.024s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.53s]
Building query seed array...  [2.256s]
Computing hash join...  [4.921s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [32.939s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.081s]
Building query seed array...  [1.841s]
Computing hash join...  [4.967s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [28.254s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.129s]
Clearing query masking...  [1.531s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.006s]
Sorting trace points...  [1.207s]
Computing alignments...  [29.522s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.051s]
Computing alignments...  [29.503s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.132s]
Computing alignments...  [29.678s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.127s]
Computing alignments...  [29.19s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.12s]
Computing alignments...  [29.282s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.061s]
Sorting trace points...  [0.845s]
Computing alignments...  [28.94s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.049s]
Sorting trace points...  [0.907s]
Computing alignments...  [28.976s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.124s]
Computing alignments...  [29.073s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.118s]
Computing alignments...  [30.328s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.092s]
Computing alignments...  [30.71s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.085s]
Sorting trace points...  [1.179s]
Computing alignments...  [31.25s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.154s]
Computing alignments...  [30.463s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.181s]
Computing alignments...  [30.522s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.191s]
Computing alignments...  [30.786s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.136s]
Computing alignments...  [30.603s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.015s]
Computing alignments...  [30.447s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [504.008s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [23.712s]
Masking reference...  [24.981s]
Initializing dictionary...  [0.063s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [26.569s]
Allocating buffers...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.248s]
Building query seed array...  [2.055s]
Computing hash join...  [4.364s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [58.186s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [10.077s]
Building query seed array...  [2.341s]
Computing hash join...  [4.324s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [37.4s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [11.607s]
Building query seed array...  [2.49s]
Computing hash join...  [4.321s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [33.56s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [8.223s]
Building query seed array...  [2.046s]
Computing hash join...  [4.321s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [30.517s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [8.015s]
Building query seed array...  [1.869s]
Computing hash join...  [4.175s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [30.902s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [9.824s]
Building query seed array...  [2.252s]
Computing hash join...  [4.11s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [24.488s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [11.25s]
Building query seed array...  [2.278s]
Computing hash join...  [4.181s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [26.58s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [8.09s]
Building query seed array...  [1.835s]
Computing hash join...  [4.183s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [23.521s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.105s]
Clearing query masking...  [1.517s]
Opening temporary output file...  [0.002s]
Computing alignments... Loading trace points...  [11.693s]
Sorting trace points...  [1.952s]
Computing alignments...  [47.288s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.146s]
Sorting trace points...  [1.885s]
Computing alignments...  [46.916s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.129s]
Sorting trace points...  [1.852s]
Computing alignments...  [46.336s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.133s]
Sorting trace points...  [1.799s]
Computing alignments...  [46.388s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.177s]
Sorting trace points...  [1.884s]
Computing alignments...  [48.658s]
Deallocating buffers...  [0.036s]
Loading trace points...  [0.171s]
Sorting trace points...  [1.635s]
Computing alignments...  [48.882s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.17s]
Sorting trace points...  [1.595s]
Computing alignments...  [48.989s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0s]
Sorting trace points...  [1.918s]
Computing alignments...  [48.413s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [409.319s]
Deallocating reference...  [0.047s]
Loading reference sequences...  [0.178s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [1765.39s]
 [1765.39s]
Deallocating queries...  [0.061s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [4.396s]
 [5.822s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 16757.5s
Reported 2196959347 pairwise alignments, 2196959347 HSPs.
13135105 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E15_R1.fastp-trim.20230215.fq.gz complete: E15_R1.blastx.meganized.daa

Now MEGANizing E15_R1.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: E15_R1.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (317.8s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.4s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (4,123.2s)
Total reads:       13,135,105
With hits:          13,135,105 
Alignments:      2,191,057,561
Assig. Taxonomy:    11,235,108
Assig. SEED:           139,800
Assig. EGGNOG:          95,970
Assig. GTDB:           480,568
Assig. EC:           1,918,015
Assig. INTERPRO2GO:  1,199,800
MinSupport set to: 6567
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.4s)
Min-supp. changes:       5,034
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (14.6s)
Min-supp. changes:       4,010
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (40.7s)
Binning reads Syncing
100% (0.4s)
Class. Taxonomy:            88
Class. SEED:               554
Class. EGGNOG:           1,938
Class. GTDB:                30
Class. EC:               2,546
Class. INTERPRO2GO:      8,054
Total time:  4,507s
Peak memory: 29.4 of 195.3G
MEGANization of E15_R1.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E15_R2.fastp-trim.20230215.fq.gz...
4cbbd2511cef487403f8612659037aae  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E15_R2.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E15_R2.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.359s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.758s]
Opening the output file...  [0s]
Loading query sequences...  [72.101s]
Masking queries...  [18.32s]
Algorithm: Double-indexed
Building query histograms...  [18.931s]
Loading reference sequences...  [29.592s]
Masking reference...  [30.852s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.216s]
Allocating buffers...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.246s]
Building query seed array...  [2.06s]
Computing hash join...  [5.471s]
Masking low complexity seeds...  [0.278s]
Searching alignments...  [71.849s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.117s]
Building query seed array...  [2.382s]
Computing hash join...  [5.274s]
Masking low complexity seeds...  [0.291s]
Searching alignments...  [45.242s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.482s]
Building query seed array...  [2.505s]
Computing hash join...  [5.31s]
Masking low complexity seeds...  [0.276s]
Searching alignments...  [41.806s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.366s]
Building query seed array...  [2.101s]
Computing hash join...  [5.366s]
Masking low complexity seeds...  [0.286s]
Searching alignments...  [36.737s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.823s]
Building query seed array...  [1.887s]
Computing hash join...  [5.069s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [39.744s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.604s]
Building query seed array...  [2.195s]
Computing hash join...  [5.07s]
Masking low complexity seeds...  [0.265s]
Searching alignments...  [30.466s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.702s]
Building query seed array...  [2.362s]
Computing hash join...  [5.05s]
Masking low complexity seeds...  [0.272s]
Searching alignments...  [33.954s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.177s]
Building query seed array...  [1.859s]
Computing hash join...  [5.132s]
Masking low complexity seeds...  [0.286s]
Searching alignments...  [29.506s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.129s]
Clearing query masking...  [1.564s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [5.923s]
Sorting trace points...  [1.146s]
Computing alignments...  [28.87s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.096s]
Sorting trace points...  [1.111s]
Computing alignments...  [29.081s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.086s]
Computing alignments...  [28.922s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.056s]
Sorting trace points...  [0.925s]
Computing alignments...  [29.674s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.045s]
Sorting trace points...  [0.991s]
Computing alignments...  [29.323s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.087s]
Computing alignments...  [29.21s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.067s]
Sorting trace points...  [0.986s]
Computing alignments...  [29.07s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.05s]
Sorting trace points...  [0.948s]
Computing alignments...  [28.821s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.04s]
Sorting trace points...  [1.217s]
Computing alignments...  [30.889s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.203s]
Computing alignments...  [31.37s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.196s]
Computing alignments...  [31.668s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.809s]
Sorting trace points...  [1.232s]
Computing alignments...  [31.483s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.212s]
Computing alignments...  [31.467s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.108s]
Sorting trace points...  [1.223s]
Computing alignments...  [31.671s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.234s]
Computing alignments...  [31.72s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.193s]
Computing alignments...  [31.385s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [510.467s]
Deallocating reference...  [0.069s]
Loading reference sequences...  [29.742s]
Masking reference...  [30.92s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.516s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.186s]
Building query seed array...  [2.038s]
Computing hash join...  [5.311s]
Masking low complexity seeds...  [0.29s]
Searching alignments...  [72.085s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.185s]
Building query seed array...  [2.431s]
Computing hash join...  [5.265s]
Masking low complexity seeds...  [0.288s]
Searching alignments...  [45.546s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.457s]
Building query seed array...  [2.483s]
Computing hash join...  [5.31s]
Masking low complexity seeds...  [0.275s]
Searching alignments...  [40.981s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.043s]
Building query seed array...  [2.079s]
Computing hash join...  [5.262s]
Masking low complexity seeds...  [0.277s]
Searching alignments...  [35.838s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.946s]
Building query seed array...  [1.877s]
Computing hash join...  [5.095s]
Masking low complexity seeds...  [0.275s]
Searching alignments...  [38.407s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.144s]
Building query seed array...  [2.229s]
Computing hash join...  [5.043s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [30.119s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.193s]
Building query seed array...  [2.359s]
Computing hash join...  [5.133s]
Masking low complexity seeds...  [0.286s]
Searching alignments...  [33.278s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.264s]
Building query seed array...  [1.829s]
Computing hash join...  [5.058s]
Masking low complexity seeds...  [0.273s]
Searching alignments...  [28.606s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.55s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [11.63s]
Sorting trace points...  [2.235s]
Computing alignments...  [57.191s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.068s]
Sorting trace points...  [0.947s]
Computing alignments...  [28.72s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.101s]
Computing alignments...  [29.455s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.099s]
Computing alignments...  [29.18s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.116s]
Sorting trace points...  [0.943s]
Computing alignments...  [28.989s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.092s]
Computing alignments...  [28.984s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.864s]
Sorting trace points...  [1.149s]
Computing alignments...  [28.757s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.04s]
Sorting trace points...  [0.873s]
Computing alignments...  [30.751s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.062s]
Sorting trace points...  [0.908s]
Computing alignments...  [31.35s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.002s]
Sorting trace points...  [0.931s]
Computing alignments...  [31.554s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.211s]
Computing alignments...  [31.405s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.087s]
Computing alignments...  [31.267s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.201s]
Computing alignments...  [31.535s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.24s]
Computing alignments...  [31.613s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0s]
Sorting trace points...  [1.181s]
Computing alignments...  [31.176s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
 [512.649s]
Deallocating reference...  [0.069s]
Loading reference sequences...  [29.62s]
Masking reference...  [30.901s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.757s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.205s]
Building query seed array...  [2.086s]
Computing hash join...  [5.374s]
Masking low complexity seeds...  [0.287s]
Searching alignments...  [74.138s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.365s]
Building query seed array...  [2.426s]
Computing hash join...  [5.358s]
Masking low complexity seeds...  [0.29s]
Searching alignments...  [44.952s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.172s]
Building query seed array...  [2.621s]
Computing hash join...  [5.197s]
Masking low complexity seeds...  [0.281s]
Searching alignments...  [40.764s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.591s]
Building query seed array...  [2.057s]
Computing hash join...  [5.274s]
Masking low complexity seeds...  [0.284s]
Searching alignments...  [36.598s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.249s]
Building query seed array...  [1.886s]
Computing hash join...  [5.068s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [39.279s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.575s]
Building query seed array...  [2.187s]
Computing hash join...  [5.107s]
Masking low complexity seeds...  [0.271s]
Searching alignments...  [30.859s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.287s]
Building query seed array...  [2.434s]
Computing hash join...  [5.125s]
Masking low complexity seeds...  [0.271s]
Searching alignments...  [33.542s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.061s]
Building query seed array...  [1.837s]
Computing hash join...  [5.007s]
Masking low complexity seeds...  [0.279s]
Searching alignments...  [29.073s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.525s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [5.869s]
Sorting trace points...  [1.137s]
Computing alignments...  [28.761s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.092s]
Computing alignments...  [28.719s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.127s]
Computing alignments...  [28.614s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.106s]
Computing alignments...  [29.375s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.06s]
Computing alignments...  [29.22s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.024s]
Computing alignments...  [29.053s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.121s]
Computing alignments...  [29.036s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0s]
Sorting trace points...  [1.073s]
Computing alignments...  [28.705s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.145s]
Computing alignments...  [30.709s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.22s]
Computing alignments...  [31.203s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.251s]
Computing alignments...  [31.519s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.163s]
Computing alignments...  [31.323s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.169s]
Computing alignments...  [31.198s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.188s]
Computing alignments...  [31.502s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.234s]
Computing alignments...  [31.562s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.157s]
Computing alignments...  [31.188s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
 [506.754s]
Deallocating reference...  [0.066s]
Loading reference sequences...  [29.776s]
Masking reference...  [32.06s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.379s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.183s]
Building query seed array...  [2.105s]
Computing hash join...  [5.377s]
Masking low complexity seeds...  [0.286s]
Searching alignments...  [71.898s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.708s]
Building query seed array...  [2.445s]
Computing hash join...  [5.212s]
Masking low complexity seeds...  [0.283s]
Searching alignments...  [46.207s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.626s]
Building query seed array...  [2.482s]
Computing hash join...  [5.344s]
Masking low complexity seeds...  [0.285s]
Searching alignments...  [42.817s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.355s]
Building query seed array...  [2.023s]
Computing hash join...  [5.264s]
Masking low complexity seeds...  [0.285s]
Searching alignments...  [36.634s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.06s]
Building query seed array...  [1.84s]
Computing hash join...  [5.047s]
Masking low complexity seeds...  [0.266s]
Searching alignments...  [38.871s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.25s]
Building query seed array...  [2.153s]
Computing hash join...  [5.042s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [30.481s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.136s]
Building query seed array...  [2.346s]
Computing hash join...  [5s]
Masking low complexity seeds...  [0.268s]
Searching alignments...  [32.707s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.78s]
Building query seed array...  [1.934s]
Computing hash join...  [5.032s]
Masking low complexity seeds...  [0.273s]
Searching alignments...  [28.029s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [1.532s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [5.841s]
Sorting trace points...  [1.151s]
Computing alignments...  [28.761s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.077s]
Computing alignments...  [28.849s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.09s]
Computing alignments...  [28.662s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.087s]
Sorting trace points...  [0.927s]
Computing alignments...  [29.44s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.097s]
Computing alignments...  [29.057s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.081s]
Sorting trace points...  [0.845s]
Computing alignments...  [29.014s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.062s]
Computing alignments...  [28.903s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [0.898s]
Computing alignments...  [28.673s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.083s]
Computing alignments...  [30.677s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.189s]
Computing alignments...  [31.229s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.173s]
Computing alignments...  [31.484s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.001s]
Sorting trace points...  [0.907s]
Computing alignments...  [31.288s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.195s]
Computing alignments...  [31.31s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.059s]
Sorting trace points...  [0.947s]
Computing alignments...  [31.585s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.194s]
Computing alignments...  [32.141s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.193s]
Computing alignments...  [31.262s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [506.236s]
Deallocating reference...  [0.069s]
Loading reference sequences...  [31.627s]
Masking reference...  [31.208s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.674s]
Allocating buffers...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.424s]
Building query seed array...  [2.155s]
Computing hash join...  [5.296s]
Masking low complexity seeds...  [0.28s]
Searching alignments...  [71.852s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.967s]
Building query seed array...  [2.411s]
Computing hash join...  [5.31s]
Masking low complexity seeds...  [0.281s]
Searching alignments...  [46.924s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.436s]
Building query seed array...  [2.523s]
Computing hash join...  [5.33s]
Masking low complexity seeds...  [0.286s]
Searching alignments...  [41.723s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.02s]
Building query seed array...  [2.091s]
Computing hash join...  [5.345s]
Masking low complexity seeds...  [0.285s]
Searching alignments...  [38.242s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.932s]
Building query seed array...  [1.908s]
Computing hash join...  [5.151s]
Masking low complexity seeds...  [0.269s]
Searching alignments...  [39.295s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.069s]
Building query seed array...  [2.144s]
Computing hash join...  [5.04s]
Masking low complexity seeds...  [0.269s]
Searching alignments...  [29.999s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.244s]
Building query seed array...  [2.275s]
Computing hash join...  [5.07s]
Masking low complexity seeds...  [0.273s]
Searching alignments...  [32.465s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.115s]
Building query seed array...  [1.886s]
Computing hash join...  [5.133s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [27.723s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.128s]
Clearing query masking...  [1.612s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [5.884s]
Sorting trace points...  [1.177s]
Computing alignments...  [28.447s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.109s]
Computing alignments...  [28.709s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.061s]
Computing alignments...  [28.533s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.104s]
Computing alignments...  [29.316s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.001s]
Sorting trace points...  [0.877s]
Computing alignments...  [28.987s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.079s]
Computing alignments...  [28.943s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.063s]
Sorting trace points...  [0.867s]
Computing alignments...  [28.828s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.087s]
Sorting trace points...  [1.12s]
Computing alignments...  [28.608s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.05s]
Sorting trace points...  [0.862s]
Computing alignments...  [30.562s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.212s]
Computing alignments...  [31.091s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.118s]
Computing alignments...  [31.467s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.103s]
Sorting trace points...  [1.196s]
Computing alignments...  [31.199s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.226s]
Computing alignments...  [31.141s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.053s]
Sorting trace points...  [0.994s]
Computing alignments...  [31.335s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.174s]
Computing alignments...  [31.427s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.225s]
Computing alignments...  [31.143s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
 [504.138s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [29.648s]
Masking reference...  [32.166s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.341s]
Allocating buffers...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.112s]
Building query seed array...  [2.097s]
Computing hash join...  [5.343s]
Masking low complexity seeds...  [0.286s]
Searching alignments...  [69.293s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.763s]
Building query seed array...  [2.411s]
Computing hash join...  [5.236s]
Masking low complexity seeds...  [0.275s]
Searching alignments...  [44.661s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.147s]
Building query seed array...  [2.601s]
Computing hash join...  [5.284s]
Masking low complexity seeds...  [0.278s]
Searching alignments...  [41.413s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.761s]
Building query seed array...  [2.017s]
Computing hash join...  [5.227s]
Masking low complexity seeds...  [0.277s]
Searching alignments...  [35.298s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.217s]
Building query seed array...  [1.861s]
Computing hash join...  [5.02s]
Masking low complexity seeds...  [0.272s]
Searching alignments...  [37.04s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.446s]
Building query seed array...  [2.091s]
Computing hash join...  [5.04s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [30.12s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.747s]
Building query seed array...  [2.334s]
Computing hash join...  [5.097s]
Masking low complexity seeds...  [0.277s]
Searching alignments...  [31.079s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.232s]
Building query seed array...  [1.884s]
Computing hash join...  [5.068s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [28.295s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.122s]
Clearing query masking...  [1.513s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [11.889s]
Sorting trace points...  [1.969s]
Computing alignments...  [57.308s]
Deallocating buffers...  [0.029s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.11s]
Computing alignments...  [28.426s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.102s]
Sorting trace points...  [0.98s]
Computing alignments...  [29.212s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.102s]
Sorting trace points...  [1.109s]
Computing alignments...  [28.919s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.053s]
Sorting trace points...  [0.843s]
Computing alignments...  [28.727s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.132s]
Computing alignments...  [28.74s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.021s]
Computing alignments...  [28.508s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.126s]
Computing alignments...  [30.56s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.224s]
Computing alignments...  [31.123s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.231s]
Computing alignments...  [31.39s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.192s]
Computing alignments...  [31.173s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.207s]
Computing alignments...  [31.15s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.162s]
Computing alignments...  [31.242s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.176s]
Computing alignments...  [31.293s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.074s]
Computing alignments...  [31.032s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [509.491s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [33.075s]
Masking reference...  [31.239s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.356s]
Allocating buffers...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.341s]
Building query seed array...  [1.984s]
Computing hash join...  [5.282s]
Masking low complexity seeds...  [0.284s]
Searching alignments...  [72.278s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.435s]
Building query seed array...  [2.359s]
Computing hash join...  [5.333s]
Masking low complexity seeds...  [0.289s]
Searching alignments...  [47.078s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.436s]
Building query seed array...  [2.612s]
Computing hash join...  [5.186s]
Masking low complexity seeds...  [0.275s]
Searching alignments...  [43.216s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.054s]
Building query seed array...  [2.058s]
Computing hash join...  [5.292s]
Masking low complexity seeds...  [0.289s]
Searching alignments...  [37.822s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.109s]
Building query seed array...  [1.841s]
Computing hash join...  [5.138s]
Masking low complexity seeds...  [0.27s]
Searching alignments...  [39.317s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.504s]
Building query seed array...  [2.198s]
Computing hash join...  [5.09s]
Masking low complexity seeds...  [0.271s]
Searching alignments...  [29.979s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.359s]
Building query seed array...  [2.35s]
Computing hash join...  [5.042s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [32.269s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.57s]
Building query seed array...  [1.863s]
Computing hash join...  [5.07s]
Masking low complexity seeds...  [0.275s]
Searching alignments...  [28.185s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.564s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [5.817s]
Sorting trace points...  [1.122s]
Computing alignments...  [28.509s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.08s]
Computing alignments...  [28.769s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.002s]
Computing alignments...  [28.542s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.003s]
Sorting trace points...  [1.084s]
Computing alignments...  [29.373s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.097s]
Computing alignments...  [29.099s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.133s]
Computing alignments...  [29.01s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.098s]
Computing alignments...  [28.995s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.097s]
Computing alignments...  [28.652s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.168s]
Computing alignments...  [30.576s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.18s]
Computing alignments...  [31.231s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.047s]
Sorting trace points...  [0.916s]
Computing alignments...  [31.839s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.196s]
Computing alignments...  [31.469s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.172s]
Computing alignments...  [31.238s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.212s]
Computing alignments...  [31.496s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.605s]
Sorting trace points...  [1.231s]
Computing alignments...  [31.503s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [0.996s]
Computing alignments...  [31.217s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [506.623s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [29.651s]
Masking reference...  [32.148s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.011s]
Building reference histograms...  [32.548s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.162s]
Building query seed array...  [2.046s]
Computing hash join...  [5.315s]
Masking low complexity seeds...  [0.284s]
Searching alignments...  [71.085s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.192s]
Building query seed array...  [2.397s]
Computing hash join...  [5.31s]
Masking low complexity seeds...  [0.289s]
Searching alignments...  [46.969s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.834s]
Building query seed array...  [2.572s]
Computing hash join...  [5.219s]
Masking low complexity seeds...  [0.28s]
Searching alignments...  [43.409s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.075s]
Building query seed array...  [2.06s]
Computing hash join...  [5.175s]
Masking low complexity seeds...  [0.285s]
Searching alignments...  [38.578s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.918s]
Building query seed array...  [1.86s]
Computing hash join...  [5.067s]
Masking low complexity seeds...  [0.268s]
Searching alignments...  [38.372s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.649s]
Building query seed array...  [2.14s]
Computing hash join...  [5.078s]
Masking low complexity seeds...  [0.271s]
Searching alignments...  [31.059s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.371s]
Building query seed array...  [2.41s]
Computing hash join...  [5.122s]
Masking low complexity seeds...  [0.282s]
Searching alignments...  [32.779s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.127s]
Building query seed array...  [1.92s]
Computing hash join...  [5.109s]
Masking low complexity seeds...  [0.284s]
Searching alignments...  [28.463s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.14s]
Clearing query masking...  [1.561s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [5.882s]
Sorting trace points...  [1.115s]
Computing alignments...  [28.521s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.127s]
Computing alignments...  [28.714s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.045s]
Computing alignments...  [28.596s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.113s]
Computing alignments...  [29.327s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.03s]
Sorting trace points...  [1.122s]
Computing alignments...  [29.054s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.131s]
Computing alignments...  [28.944s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.053s]
Sorting trace points...  [0.928s]
Computing alignments...  [28.858s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.002s]
Sorting trace points...  [1.085s]
Computing alignments...  [28.6s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.132s]
Sorting trace points...  [1.178s]
Computing alignments...  [30.648s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.164s]
Computing alignments...  [31.229s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.042s]
Sorting trace points...  [1.214s]
Computing alignments...  [31.482s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.035s]
Sorting trace points...  [1.181s]
Computing alignments...  [31.608s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.087s]
Computing alignments...  [31.241s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.219s]
Computing alignments...  [31.489s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.186s]
Computing alignments...  [31.564s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.207s]
Computing alignments...  [31.226s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
 [506.135s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [29.848s]
Masking reference...  [32.019s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.3s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.353s]
Building query seed array...  [2.046s]
Computing hash join...  [5.32s]
Masking low complexity seeds...  [0.282s]
Searching alignments...  [69.307s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.265s]
Building query seed array...  [2.443s]
Computing hash join...  [5.301s]
Masking low complexity seeds...  [0.28s]
Searching alignments...  [47.317s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [14.057s]
Building query seed array...  [2.604s]
Computing hash join...  [5.331s]
Masking low complexity seeds...  [0.28s]
Searching alignments...  [42.059s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.787s]
Building query seed array...  [2.101s]
Computing hash join...  [5.336s]
Masking low complexity seeds...  [0.285s]
Searching alignments...  [38.955s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.896s]
Building query seed array...  [1.879s]
Computing hash join...  [5.128s]
Masking low complexity seeds...  [0.267s]
Searching alignments...  [39.917s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.144s]
Building query seed array...  [2.157s]
Computing hash join...  [5.121s]
Masking low complexity seeds...  [0.265s]
Searching alignments...  [30.85s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.421s]
Building query seed array...  [2.226s]
Computing hash join...  [5.078s]
Masking low complexity seeds...  [0.265s]
Searching alignments...  [32.927s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.894s]
Building query seed array...  [1.889s]
Computing hash join...  [5.062s]
Masking low complexity seeds...  [0.271s]
Searching alignments...  [28.519s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.485s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [5.832s]
Sorting trace points...  [1.07s]
Computing alignments...  [28.668s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.061s]
Sorting trace points...  [0.893s]
Computing alignments...  [28.763s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.065s]
Computing alignments...  [28.595s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.093s]
Sorting trace points...  [1.103s]
Computing alignments...  [29.319s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.089s]
Computing alignments...  [29.126s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.084s]
Sorting trace points...  [0.929s]
Computing alignments...  [28.944s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.046s]
Sorting trace points...  [0.877s]
Computing alignments...  [29.001s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.076s]
Sorting trace points...  [0.869s]
Computing alignments...  [28.717s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.039s]
Sorting trace points...  [1.067s]
Computing alignments...  [30.726s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.043s]
Computing alignments...  [31.29s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.394s]
Sorting trace points...  [1.208s]
Computing alignments...  [31.549s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.096s]
Sorting trace points...  [1.161s]
Computing alignments...  [31.274s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.186s]
Computing alignments...  [31.312s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.184s]
Computing alignments...  [31.471s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.058s]
Sorting trace points...  [0.953s]
Computing alignments...  [31.527s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.192s]
Computing alignments...  [31.229s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [505.733s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.564s]
Masking reference...  [31.977s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.874s]
Allocating buffers...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.618s]
Building query seed array...  [2.099s]
Computing hash join...  [5.396s]
Masking low complexity seeds...  [0.284s]
Searching alignments...  [72.06s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.365s]
Building query seed array...  [2.398s]
Computing hash join...  [5.213s]
Masking low complexity seeds...  [0.286s]
Searching alignments...  [46.883s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.605s]
Building query seed array...  [2.58s]
Computing hash join...  [5.296s]
Masking low complexity seeds...  [0.29s]
Searching alignments...  [41.546s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.949s]
Building query seed array...  [2.062s]
Computing hash join...  [5.264s]
Masking low complexity seeds...  [0.283s]
Searching alignments...  [38.198s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.752s]
Building query seed array...  [1.946s]
Computing hash join...  [5.076s]
Masking low complexity seeds...  [0.275s]
Searching alignments...  [40.091s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.39s]
Building query seed array...  [2.176s]
Computing hash join...  [5.08s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [30.891s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.25s]
Building query seed array...  [2.32s]
Computing hash join...  [5.05s]
Masking low complexity seeds...  [0.27s]
Searching alignments...  [33.118s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.727s]
Building query seed array...  [1.856s]
Computing hash join...  [5.055s]
Masking low complexity seeds...  [0.275s]
Searching alignments...  [28.61s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.138s]
Clearing query masking...  [1.516s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [5.862s]
Sorting trace points...  [1.156s]
Computing alignments...  [28.615s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.069s]
Computing alignments...  [28.725s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.09s]
Sorting trace points...  [1.088s]
Computing alignments...  [28.671s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.006s]
Computing alignments...  [29.332s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.097s]
Computing alignments...  [29.067s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.098s]
Computing alignments...  [28.978s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.077s]
Computing alignments...  [28.893s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.074s]
Computing alignments...  [28.607s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.137s]
Computing alignments...  [30.641s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.11s]
Sorting trace points...  [0.979s]
Computing alignments...  [31.156s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.239s]
Computing alignments...  [31.405s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.118s]
Computing alignments...  [31.184s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.256s]
Computing alignments...  [31.169s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.191s]
Computing alignments...  [31.435s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.105s]
Sorting trace points...  [1.166s]
Computing alignments...  [31.399s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.186s]
Computing alignments...  [31.135s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [505.434s]
Deallocating reference...  [0.063s]
Loading reference sequences...  [29.822s]
Masking reference...  [30.838s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.875s]
Allocating buffers...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.456s]
Building query seed array...  [2.096s]
Computing hash join...  [5.28s]
Masking low complexity seeds...  [0.287s]
Searching alignments...  [70.176s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.306s]
Building query seed array...  [2.442s]
Computing hash join...  [5.238s]
Masking low complexity seeds...  [0.29s]
Searching alignments...  [46.821s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.489s]
Building query seed array...  [2.529s]
Computing hash join...  [5.242s]
Masking low complexity seeds...  [0.284s]
Searching alignments...  [42.509s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.478s]
Building query seed array...  [2.039s]
Computing hash join...  [5.249s]
Masking low complexity seeds...  [0.28s]
Searching alignments...  [35.457s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.14s]
Building query seed array...  [1.822s]
Computing hash join...  [5.16s]
Masking low complexity seeds...  [0.272s]
Searching alignments...  [38.148s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.217s]
Building query seed array...  [2.155s]
Computing hash join...  [5.002s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [30.638s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.268s]
Building query seed array...  [2.32s]
Computing hash join...  [5.08s]
Masking low complexity seeds...  [0.267s]
Searching alignments...  [33.012s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.958s]
Building query seed array...  [1.881s]
Computing hash join...  [5.072s]
Masking low complexity seeds...  [0.278s]
Searching alignments...  [28.065s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.564s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [11.589s]
Sorting trace points...  [2.321s]
Computing alignments...  [56.885s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.052s]
Sorting trace points...  [0.92s]
Computing alignments...  [28.65s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.042s]
Computing alignments...  [29.369s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.1s]
Computing alignments...  [29.009s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.092s]
Computing alignments...  [28.912s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.119s]
Sorting trace points...  [1.122s]
Computing alignments...  [28.951s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.119s]
Computing alignments...  [28.622s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.062s]
Sorting trace points...  [0.862s]
Computing alignments...  [30.649s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.056s]
Sorting trace points...  [0.943s]
Computing alignments...  [31.197s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.087s]
Sorting trace points...  [0.993s]
Computing alignments...  [31.704s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.097s]
Sorting trace points...  [1.055s]
Computing alignments...  [31.215s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.218s]
Computing alignments...  [31.222s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.2s]
Computing alignments...  [31.538s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.048s]
Sorting trace points...  [0.915s]
Computing alignments...  [31.45s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.209s]
Computing alignments...  [31.186s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
 [510.73s]
Deallocating reference...  [0.071s]
Loading reference sequences...  [29.567s]
Masking reference...  [30.861s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.541s]
Allocating buffers...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.319s]
Building query seed array...  [2.019s]
Computing hash join...  [5.273s]
Masking low complexity seeds...  [0.286s]
Searching alignments...  [71.909s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.615s]
Building query seed array...  [2.369s]
Computing hash join...  [5.189s]
Masking low complexity seeds...  [0.283s]
Searching alignments...  [47.031s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.767s]
Building query seed array...  [2.564s]
Computing hash join...  [5.275s]
Masking low complexity seeds...  [0.288s]
Searching alignments...  [41.182s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.836s]
Building query seed array...  [2.026s]
Computing hash join...  [5.292s]
Masking low complexity seeds...  [0.287s]
Searching alignments...  [37.936s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.124s]
Building query seed array...  [1.854s]
Computing hash join...  [5.021s]
Masking low complexity seeds...  [0.266s]
Searching alignments...  [40.269s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.997s]
Building query seed array...  [2.193s]
Computing hash join...  [5.112s]
Masking low complexity seeds...  [0.272s]
Searching alignments...  [31.295s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.337s]
Building query seed array...  [2.277s]
Computing hash join...  [4.986s]
Masking low complexity seeds...  [0.271s]
Searching alignments...  [33.335s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.12s]
Building query seed array...  [1.863s]
Computing hash join...  [5.035s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [28.688s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.571s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [5.87s]
Sorting trace points...  [1.181s]
Computing alignments...  [28.634s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.091s]
Computing alignments...  [28.695s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.074s]
Computing alignments...  [28.459s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.107s]
Computing alignments...  [29.322s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.121s]
Computing alignments...  [29.029s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.088s]
Computing alignments...  [28.921s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.08s]
Sorting trace points...  [0.859s]
Computing alignments...  [28.917s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.084s]
Computing alignments...  [28.632s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.191s]
Computing alignments...  [30.636s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.047s]
Sorting trace points...  [0.9s]
Computing alignments...  [31.238s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.034s]
Computing alignments...  [31.463s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.173s]
Computing alignments...  [31.247s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.183s]
Computing alignments...  [31.206s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.211s]
Computing alignments...  [31.368s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.214s]
Computing alignments...  [31.523s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [0.922s]
Computing alignments...  [31.167s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [504.903s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [29.537s]
Masking reference...  [30.838s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.506s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.14s]
Building query seed array...  [2.126s]
Computing hash join...  [5.254s]
Masking low complexity seeds...  [0.279s]
Searching alignments...  [72.011s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.693s]
Building query seed array...  [2.35s]
Computing hash join...  [5.235s]
Masking low complexity seeds...  [0.285s]
Searching alignments...  [46.228s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.671s]
Building query seed array...  [2.497s]
Computing hash join...  [5.279s]
Masking low complexity seeds...  [0.279s]
Searching alignments...  [41.526s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.149s]
Building query seed array...  [2.083s]
Computing hash join...  [5.255s]
Masking low complexity seeds...  [0.276s]
Searching alignments...  [36.551s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.067s]
Building query seed array...  [1.906s]
Computing hash join...  [5.104s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [39.924s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.646s]
Building query seed array...  [2.176s]
Computing hash join...  [5.005s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [30.783s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [14.269s]
Building query seed array...  [2.277s]
Computing hash join...  [5.176s]
Masking low complexity seeds...  [0.271s]
Searching alignments...  [34.649s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.952s]
Building query seed array...  [1.901s]
Computing hash join...  [5.091s]
Masking low complexity seeds...  [0.276s]
Searching alignments...  [29.67s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.127s]
Clearing query masking...  [1.555s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [11.887s]
Sorting trace points...  [2.271s]
Computing alignments...  [56.953s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.109s]
Computing alignments...  [28.608s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.015s]
Computing alignments...  [29.318s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [0.833s]
Computing alignments...  [29.053s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.06s]
Computing alignments...  [28.957s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.076s]
Computing alignments...  [28.952s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.119s]
Computing alignments...  [28.663s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.172s]
Computing alignments...  [30.65s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.175s]
Computing alignments...  [31.191s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.002s]
Sorting trace points...  [1.207s]
Computing alignments...  [31.547s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.623s]
Sorting trace points...  [0.979s]
Computing alignments...  [31.391s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.162s]
Computing alignments...  [31.194s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.197s]
Computing alignments...  [31.493s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.196s]
Computing alignments...  [31.542s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.202s]
Computing alignments...  [31.182s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [511.983s]
Deallocating reference...  [0.069s]
Loading reference sequences...  [25.943s]
Masking reference...  [26.082s]
Initializing dictionary...  [0.063s]
Initializing temporary storage...  [0.011s]
Building reference histograms...  [26.587s]
Allocating buffers...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.369s]
Building query seed array...  [2.231s]
Computing hash join...  [4.427s]
Masking low complexity seeds...  [0.272s]
Searching alignments...  [59.102s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [10.045s]
Building query seed array...  [2.444s]
Computing hash join...  [4.38s]
Masking low complexity seeds...  [0.275s]
Searching alignments...  [38.402s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [11.171s]
Building query seed array...  [2.498s]
Computing hash join...  [4.473s]
Masking low complexity seeds...  [0.273s]
Searching alignments...  [33.578s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [8.523s]
Building query seed array...  [2.007s]
Computing hash join...  [4.417s]
Masking low complexity seeds...  [0.269s]
Searching alignments...  [29.475s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [7.996s]
Building query seed array...  [1.877s]
Computing hash join...  [4.308s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [30.957s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [10.234s]
Building query seed array...  [2.157s]
Computing hash join...  [4.199s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [25.771s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [10.785s]
Building query seed array...  [2.287s]
Computing hash join...  [4.19s]
Masking low complexity seeds...  [0.266s]
Searching alignments...  [27.183s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [8.067s]
Building query seed array...  [1.839s]
Computing hash join...  [4.207s]
Masking low complexity seeds...  [0.256s]
Searching alignments...  [22.913s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.108s]
Clearing query masking...  [1.531s]
Opening temporary output file...  [0.017s]
Computing alignments... Loading trace points...  [9.813s]
Sorting trace points...  [1.841s]
Computing alignments...  [45.751s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.851s]
Computing alignments...  [46.1s]
Deallocating buffers...  [0.032s]
Loading trace points...  [0.153s]
Sorting trace points...  [1.784s]
Computing alignments...  [46.102s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.123s]
Sorting trace points...  [1.756s]
Computing alignments...  [45.856s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.109s]
Sorting trace points...  [1.969s]
Computing alignments...  [49.225s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.142s]
Sorting trace points...  [2.033s]
Computing alignments...  [49.996s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.129s]
Sorting trace points...  [1.967s]
Computing alignments...  [49.965s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
Sorting trace points...  [1.585s]
Computing alignments...  [49.622s]
Deallocating buffers...  [0.03s]
Loading trace points...  [0s]
 [408.224s]
Deallocating reference...  [0.054s]
Loading reference sequences...  [0.082s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [1748.54s]
 [1748.54s]
Deallocating queries...  [0.048s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [4.494s]
 [5.833s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 16856.1s
Reported 2133286035 pairwise alignments, 2133286035 HSPs.
13480628 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E15_R2.fastp-trim.20230215.fq.gz complete: E15_R2.blastx.meganized.daa

Now MEGANizing E15_R2.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: E15_R2.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (356.9s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.5s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (4,051.2s)
Total reads:       13,480,628
With hits:          13,480,628 
Alignments:      2,129,083,592
Assig. Taxonomy:    11,473,607
Assig. SEED:           136,158
Assig. EGGNOG:          95,235
Assig. GTDB:           466,636
Assig. EC:           1,955,474
Assig. INTERPRO2GO:  1,190,669
MinSupport set to: 6740
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.5s)
Min-supp. changes:       5,091
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (13.0s)
Min-supp. changes:       4,212
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (32.0s)
Binning reads Syncing
100% (0.4s)
Class. Taxonomy:            85
Class. SEED:               553
Class. EGGNOG:           1,932
Class. GTDB:                27
Class. EC:               2,524
Class. INTERPRO2GO:      8,057
Total time:  4,464s
Peak memory: 29.8 of 195.3G
MEGANization of E15_R2.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E16_R1.fastp-trim.20230215.fq.gz...
65541adbec9cbb5133f1484bfdffeebe  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E16_R1.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E16_R1.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.336s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.699s]
Opening the output file...  [0s]
Loading query sequences...  [91.105s]
Masking queries...  [23.123s]
Algorithm: Double-indexed
Building query histograms...  [26.448s]
Loading reference sequences...  [29.781s]
Masking reference...  [30.989s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.268s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.19s]
Building query seed array...  [2.564s]
Computing hash join...  [5.316s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [89.043s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.717s]
Building query seed array...  [2.946s]
Computing hash join...  [5.291s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [58.256s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.171s]
Building query seed array...  [3.134s]
Computing hash join...  [5.366s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [51.817s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.167s]
Building query seed array...  [2.564s]
Computing hash join...  [5.369s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [44.803s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.967s]
Building query seed array...  [2.3s]
Computing hash join...  [5.012s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [44.958s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.2s]
Building query seed array...  [2.588s]
Computing hash join...  [5.107s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [36.671s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.15s]
Building query seed array...  [2.791s]
Computing hash join...  [5.036s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [40.689s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.004s]
Building query seed array...  [2.259s]
Computing hash join...  [5.03s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [35.603s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.13s]
Clearing query masking...  [1.96s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [7.209s]
Sorting trace points...  [1.472s]
Computing alignments...  [36.861s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.38s]
Computing alignments...  [37.2s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.288s]
Computing alignments...  [36.883s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.314s]
Computing alignments...  [36.693s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.065s]
Computing alignments...  [36.899s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.41s]
Computing alignments...  [37.152s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.34s]
Computing alignments...  [36.635s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.236s]
Computing alignments...  [36.981s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.067s]
Computing alignments...  [37.248s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.436s]
Computing alignments...  [38.701s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.216s]
Computing alignments...  [38.622s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.002s]
Sorting trace points...  [1.529s]
Computing alignments...  [38.843s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.445s]
Computing alignments...  [38.814s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.449s]
Computing alignments...  [38.945s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.036s]
Sorting trace points...  [1.209s]
Computing alignments...  [38.996s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.41s]
Computing alignments...  [38.463s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [633.541s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [29.162s]
Masking reference...  [32.206s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.541s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.273s]
Building query seed array...  [2.587s]
Computing hash join...  [5.336s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [89.109s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.797s]
Building query seed array...  [2.91s]
Computing hash join...  [5.397s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [57.345s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.596s]
Building query seed array...  [3.064s]
Computing hash join...  [5.274s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [50.055s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.547s]
Building query seed array...  [2.573s]
Computing hash join...  [5.3s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [44.271s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.948s]
Building query seed array...  [2.222s]
Computing hash join...  [4.998s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [43.94s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.196s]
Building query seed array...  [2.586s]
Computing hash join...  [5.02s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [35.906s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.16s]
Building query seed array...  [2.767s]
Computing hash join...  [5.108s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [38.704s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.867s]
Building query seed array...  [2.244s]
Computing hash join...  [4.996s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [34.002s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.145s]
Clearing query masking...  [2.006s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.558s]
Sorting trace points...  [1.513s]
Computing alignments...  [36.743s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.46s]
Computing alignments...  [37.045s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.326s]
Computing alignments...  [36.715s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.392s]
Computing alignments...  [36.629s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.167s]
Computing alignments...  [36.844s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.084s]
Sorting trace points...  [1.456s]
Computing alignments...  [36.957s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.358s]
Computing alignments...  [36.544s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.252s]
Computing alignments...  [36.876s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.236s]
Computing alignments...  [37.103s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.094s]
Sorting trace points...  [1.444s]
Computing alignments...  [38.535s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.484s]
Computing alignments...  [38.398s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.398s]
Computing alignments...  [38.537s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.457s]
Computing alignments...  [38.489s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.53s]
Computing alignments...  [38.591s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.397s]
Computing alignments...  [38.675s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.161s]
Computing alignments...  [38.265s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [631.782s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [29.523s]
Masking reference...  [30.97s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.795s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [9.941s]
Building query seed array...  [2.534s]
Computing hash join...  [5.346s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [89.499s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.224s]
Building query seed array...  [2.895s]
Computing hash join...  [5.278s]
Masking low complexity seeds...  [0.249s]
Searching alignments...  [56.646s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.488s]
Building query seed array...  [3.027s]
Computing hash join...  [5.323s]
Masking low complexity seeds...  [0.239s]
Searching alignments...  [50.818s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.028s]
Building query seed array...  [2.444s]
Computing hash join...  [5.204s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [45.859s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.933s]
Building query seed array...  [2.221s]
Computing hash join...  [5.022s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [46.288s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.715s]
Building query seed array...  [2.563s]
Computing hash join...  [5.086s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [37.345s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.088s]
Building query seed array...  [2.745s]
Computing hash join...  [5.008s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [40.2s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.93s]
Building query seed array...  [2.332s]
Computing hash join...  [5.033s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [34.801s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.138s]
Clearing query masking...  [1.988s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.157s]
Sorting trace points...  [1.483s]
Computing alignments...  [36.692s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.667s]
Sorting trace points...  [1.343s]
Computing alignments...  [37.254s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.039s]
Sorting trace points...  [1.439s]
Computing alignments...  [37.028s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.125s]
Computing alignments...  [36.797s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.085s]
Sorting trace points...  [1.381s]
Computing alignments...  [37.01s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.035s]
Sorting trace points...  [1.422s]
Computing alignments...  [37.208s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.4s]
Computing alignments...  [36.636s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.407s]
Computing alignments...  [36.949s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.438s]
Computing alignments...  [37.461s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.478s]
Computing alignments...  [38.795s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.495s]
Computing alignments...  [38.653s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.469s]
Computing alignments...  [38.789s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.494s]
Computing alignments...  [38.707s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.478s]
Computing alignments...  [38.754s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.467s]
Computing alignments...  [38.948s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.435s]
Computing alignments...  [38.438s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [635.755s]
Deallocating reference...  [0.065s]
Loading reference sequences...  [29.627s]
Masking reference...  [30.912s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.011s]
Building reference histograms...  [32.828s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.18s]
Building query seed array...  [2.456s]
Computing hash join...  [5.311s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [87.818s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.319s]
Building query seed array...  [2.953s]
Computing hash join...  [5.313s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [58.285s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.588s]
Building query seed array...  [3.06s]
Computing hash join...  [5.232s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [51.66s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.156s]
Building query seed array...  [2.517s]
Computing hash join...  [5.29s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [44.478s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.988s]
Building query seed array...  [2.306s]
Computing hash join...  [5.103s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [44.778s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.229s]
Building query seed array...  [2.674s]
Computing hash join...  [5.045s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [36.064s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.521s]
Building query seed array...  [2.801s]
Computing hash join...  [5.021s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [38.557s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.922s]
Building query seed array...  [2.306s]
Computing hash join...  [5.021s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [34.456s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.135s]
Clearing query masking...  [1.967s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.242s]
Sorting trace points...  [1.48s]
Computing alignments...  [36.86s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.088s]
Sorting trace points...  [1.437s]
Computing alignments...  [37.022s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.218s]
Sorting trace points...  [1.398s]
Computing alignments...  [36.818s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.085s]
Sorting trace points...  [1.19s]
Computing alignments...  [36.568s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.423s]
Computing alignments...  [36.839s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.45s]
Computing alignments...  [36.943s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.445s]
Computing alignments...  [36.419s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.337s]
Computing alignments...  [36.657s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.427s]
Computing alignments...  [37.092s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.483s]
Computing alignments...  [38.591s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.501s]
Computing alignments...  [38.367s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.462s]
Computing alignments...  [38.527s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.367s]
Computing alignments...  [38.539s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.51s]
Computing alignments...  [38.704s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.404s]
Computing alignments...  [38.812s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.426s]
Computing alignments...  [38.295s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [632.331s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [29.425s]
Masking reference...  [30.843s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.692s]
Allocating buffers...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.229s]
Building query seed array...  [2.538s]
Computing hash join...  [5.271s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [88.272s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.233s]
Building query seed array...  [2.989s]
Computing hash join...  [5.202s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [57.174s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.524s]
Building query seed array...  [3.012s]
Computing hash join...  [5.243s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [49.762s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.103s]
Building query seed array...  [2.489s]
Computing hash join...  [5.201s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [44.071s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.967s]
Building query seed array...  [2.26s]
Computing hash join...  [5.024s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [44.732s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.167s]
Building query seed array...  [2.691s]
Computing hash join...  [5.068s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [35.794s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.215s]
Building query seed array...  [2.773s]
Computing hash join...  [4.965s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [38.714s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.683s]
Building query seed array...  [2.235s]
Computing hash join...  [5.092s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [34.326s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.934s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [8.082s]
Sorting trace points...  [1.488s]
Computing alignments...  [36.428s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.22s]
Computing alignments...  [36.904s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.427s]
Computing alignments...  [36.708s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.393s]
Computing alignments...  [36.292s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.406s]
Computing alignments...  [36.581s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0s]
Sorting trace points...  [1.313s]
Computing alignments...  [36.802s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.072s]
Computing alignments...  [36.432s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.394s]
Computing alignments...  [36.675s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.325s]
Computing alignments...  [37.054s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.323s]
Computing alignments...  [38.771s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.234s]
Computing alignments...  [38.336s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.478s]
Computing alignments...  [38.53s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.241s]
Computing alignments...  [38.407s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.438s]
Computing alignments...  [38.413s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.16s]
Computing alignments...  [38.459s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.393s]
Computing alignments...  [38.105s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [629.396s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.637s]
Masking reference...  [31.059s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.42s]
Allocating buffers...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.136s]
Building query seed array...  [2.563s]
Computing hash join...  [5.217s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [86.594s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.084s]
Building query seed array...  [2.899s]
Computing hash join...  [5.258s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [55.014s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.784s]
Building query seed array...  [2.988s]
Computing hash join...  [5.339s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [49.617s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.274s]
Building query seed array...  [2.553s]
Computing hash join...  [5.194s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [45.665s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.328s]
Building query seed array...  [2.291s]
Computing hash join...  [5.092s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [44.409s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.163s]
Building query seed array...  [2.558s]
Computing hash join...  [4.998s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [35.993s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.183s]
Building query seed array...  [2.757s]
Computing hash join...  [5.018s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [39.814s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.31s]
Building query seed array...  [2.259s]
Computing hash join...  [5.078s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [33.327s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.987s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.083s]
Sorting trace points...  [1.496s]
Computing alignments...  [36.417s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.484s]
Computing alignments...  [36.778s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.202s]
Computing alignments...  [36.551s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.359s]
Computing alignments...  [36.335s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.266s]
Computing alignments...  [36.466s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.3s]
Computing alignments...  [36.635s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.601s]
Sorting trace points...  [1.394s]
Computing alignments...  [36.17s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.382s]
Computing alignments...  [36.497s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.49s]
Computing alignments...  [36.921s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.087s]
Sorting trace points...  [1.465s]
Computing alignments...  [38.259s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.079s]
Computing alignments...  [38.217s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.277s]
Computing alignments...  [38.479s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.505s]
Computing alignments...  [38.262s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.462s]
Computing alignments...  [38.354s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.443s]
Computing alignments...  [38.481s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.135s]
Computing alignments...  [38.03s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
 [627.464s]
Deallocating reference...  [0.064s]
Loading reference sequences...  [33.488s]
Masking reference...  [31.407s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.242s]
Allocating buffers...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.766s]
Building query seed array...  [2.52s]
Computing hash join...  [5.255s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [88.314s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.396s]
Building query seed array...  [3.048s]
Computing hash join...  [5.227s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [58.364s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.276s]
Building query seed array...  [3.137s]
Computing hash join...  [5.214s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [52.674s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.096s]
Building query seed array...  [2.489s]
Computing hash join...  [5.215s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [45.269s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.918s]
Building query seed array...  [2.269s]
Computing hash join...  [5.066s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [44.683s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.625s]
Building query seed array...  [2.546s]
Computing hash join...  [5.052s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [36.698s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.386s]
Building query seed array...  [2.761s]
Computing hash join...  [4.987s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [39.743s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.259s]
Building query seed array...  [2.28s]
Computing hash join...  [5.002s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [34.378s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.127s]
Clearing query masking...  [1.991s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.14s]
Sorting trace points...  [1.472s]
Computing alignments...  [36.517s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.462s]
Computing alignments...  [37.105s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.409s]
Computing alignments...  [36.787s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.428s]
Computing alignments...  [36.533s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.09s]
Sorting trace points...  [1.058s]
Computing alignments...  [36.739s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.089s]
Sorting trace points...  [1.452s]
Computing alignments...  [36.948s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.216s]
Computing alignments...  [36.638s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.407s]
Computing alignments...  [36.818s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.042s]
Sorting trace points...  [1.207s]
Computing alignments...  [37.216s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.425s]
Computing alignments...  [38.624s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.411s]
Computing alignments...  [38.524s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.002s]
Sorting trace points...  [1.232s]
Computing alignments...  [38.664s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.448s]
Computing alignments...  [38.471s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.109s]
Computing alignments...  [38.461s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.542s]
Computing alignments...  [38.529s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.45s]
Computing alignments...  [38.061s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [630.711s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [29.964s]
Masking reference...  [30.832s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.858s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.568s]
Building query seed array...  [2.432s]
Computing hash join...  [5.374s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [87.526s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.727s]
Building query seed array...  [2.908s]
Computing hash join...  [5.333s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [57.106s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.458s]
Building query seed array...  [3.076s]
Computing hash join...  [5.232s]
Masking low complexity seeds...  [0.257s]
Searching alignments...  [50.549s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.025s]
Building query seed array...  [2.546s]
Computing hash join...  [5.251s]
Masking low complexity seeds...  [0.248s]
Searching alignments...  [45.047s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.247s]
Building query seed array...  [2.218s]
Computing hash join...  [5.086s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [44.094s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.294s]
Building query seed array...  [2.565s]
Computing hash join...  [5.042s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [35.897s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.937s]
Building query seed array...  [2.8s]
Computing hash join...  [5.09s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [39.161s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.303s]
Building query seed array...  [2.244s]
Computing hash join...  [5.077s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [34.193s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.897s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.156s]
Sorting trace points...  [1.527s]
Computing alignments...  [36.507s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.493s]
Computing alignments...  [36.904s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.378s]
Computing alignments...  [36.783s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.322s]
Computing alignments...  [36.407s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.398s]
Computing alignments...  [36.721s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.316s]
Computing alignments...  [36.833s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.388s]
Computing alignments...  [36.476s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.129s]
Computing alignments...  [36.697s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.447s]
Computing alignments...  [37.073s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.527s]
Computing alignments...  [38.366s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.534s]
Computing alignments...  [38.293s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.444s]
Computing alignments...  [38.522s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.042s]
Sorting trace points...  [1.524s]
Computing alignments...  [38.573s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.223s]
Computing alignments...  [38.733s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.469s]
Computing alignments...  [38.801s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.47s]
Computing alignments...  [38.326s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [630.886s]
Deallocating reference...  [0.068s]
Loading reference sequences...  [29.508s]
Masking reference...  [32.108s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.078s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.067s]
Building query seed array...  [2.502s]
Computing hash join...  [5.242s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [89.172s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.162s]
Building query seed array...  [2.925s]
Computing hash join...  [5.332s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [57.723s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.605s]
Building query seed array...  [3.029s]
Computing hash join...  [5.247s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [50.052s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.913s]
Building query seed array...  [2.515s]
Computing hash join...  [5.261s]
Masking low complexity seeds...  [0.238s]
Searching alignments...  [45.142s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.725s]
Building query seed array...  [2.315s]
Computing hash join...  [5.033s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [44.585s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.553s]
Building query seed array...  [2.598s]
Computing hash join...  [4.931s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [36.569s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.309s]
Building query seed array...  [2.833s]
Computing hash join...  [5.03s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [39.309s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.826s]
Building query seed array...  [2.376s]
Computing hash join...  [5.035s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [34.617s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.132s]
Clearing query masking...  [1.866s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.13s]
Sorting trace points...  [1.511s]
Computing alignments...  [36.373s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.219s]
Computing alignments...  [36.804s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.376s]
Computing alignments...  [36.672s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.341s]
Computing alignments...  [36.37s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.094s]
Sorting trace points...  [1.037s]
Computing alignments...  [36.529s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.431s]
Computing alignments...  [36.708s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.031s]
Computing alignments...  [36.288s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.411s]
Computing alignments...  [36.56s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.09s]
Sorting trace points...  [1.403s]
Computing alignments...  [37.018s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.484s]
Computing alignments...  [38.367s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.249s]
Computing alignments...  [38.28s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.106s]
Sorting trace points...  [1.302s]
Computing alignments...  [38.404s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.435s]
Computing alignments...  [38.299s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.47s]
Computing alignments...  [38.429s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.241s]
Computing alignments...  [38.68s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.502s]
Computing alignments...  [38.289s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
 [627.793s]
Deallocating reference...  [0.069s]
Loading reference sequences...  [30.033s]
Masking reference...  [32.152s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.406s]
Allocating buffers...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.334s]
Building query seed array...  [2.463s]
Computing hash join...  [5.327s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [88.733s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.436s]
Building query seed array...  [2.895s]
Computing hash join...  [5.295s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [57.248s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.434s]
Building query seed array...  [3.069s]
Computing hash join...  [5.193s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [51.748s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.26s]
Building query seed array...  [2.518s]
Computing hash join...  [5.23s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [46.353s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.326s]
Building query seed array...  [2.232s]
Computing hash join...  [4.982s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [45.727s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.144s]
Building query seed array...  [2.551s]
Computing hash join...  [5.067s]
Masking low complexity seeds...  [0.237s]
Searching alignments...  [37.052s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.834s]
Building query seed array...  [2.766s]
Computing hash join...  [5.001s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [39.781s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.402s]
Building query seed array...  [2.31s]
Computing hash join...  [5.068s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [34.591s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.137s]
Clearing query masking...  [1.925s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.419s]
Sorting trace points...  [1.434s]
Computing alignments...  [36.384s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.159s]
Computing alignments...  [36.861s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.286s]
Computing alignments...  [36.643s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.081s]
Computing alignments...  [36.278s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.443s]
Computing alignments...  [36.598s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
Sorting trace points...  [1.403s]
Computing alignments...  [36.846s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.387s]
Computing alignments...  [36.363s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.403s]
Sorting trace points...  [1.302s]
Computing alignments...  [36.607s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.105s]
Sorting trace points...  [1.329s]
Computing alignments...  [37.176s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.082s]
Sorting trace points...  [1.268s]
Computing alignments...  [38.399s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.55s]
Computing alignments...  [38.197s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.088s]
Sorting trace points...  [1.493s]
Computing alignments...  [38.506s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.474s]
Computing alignments...  [38.498s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.375s]
Computing alignments...  [38.553s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.434s]
Computing alignments...  [38.555s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.496s]
Computing alignments...  [37.98s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [629.228s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [29.791s]
Masking reference...  [30.881s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.09s]
Allocating buffers...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.743s]
Building query seed array...  [2.553s]
Computing hash join...  [5.284s]
Masking low complexity seeds...  [0.244s]
Searching alignments...  [88.188s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.802s]
Building query seed array...  [2.906s]
Computing hash join...  [5.292s]
Masking low complexity seeds...  [0.243s]
Searching alignments...  [56.247s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.196s]
Building query seed array...  [3.098s]
Computing hash join...  [5.409s]
Masking low complexity seeds...  [0.247s]
Searching alignments...  [50.855s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.984s]
Building query seed array...  [2.419s]
Computing hash join...  [5.203s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [43.334s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.176s]
Building query seed array...  [2.203s]
Computing hash join...  [4.982s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [44.642s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.222s]
Building query seed array...  [2.657s]
Computing hash join...  [4.973s]
Masking low complexity seeds...  [0.24s]
Searching alignments...  [35.801s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.167s]
Building query seed array...  [2.784s]
Computing hash join...  [4.991s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [39.752s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.956s]
Building query seed array...  [2.255s]
Computing hash join...  [5.061s]
Masking low complexity seeds...  [0.234s]
Searching alignments...  [33.942s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.126s]
Clearing query masking...  [2.015s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.925s]
Sorting trace points...  [1.49s]
Computing alignments...  [36.416s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.219s]
Sorting trace points...  [1.128s]
Computing alignments...  [36.805s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.418s]
Computing alignments...  [36.726s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.413s]
Computing alignments...  [36.388s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.404s]
Computing alignments...  [36.532s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.404s]
Computing alignments...  [36.597s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.374s]
Computing alignments...  [36.289s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.144s]
Sorting trace points...  [1.116s]
Computing alignments...  [36.625s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.371s]
Computing alignments...  [37.04s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.518s]
Computing alignments...  [38.305s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0s]
Sorting trace points...  [1.479s]
Computing alignments...  [38.284s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.491s]
Computing alignments...  [38.415s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.143s]
Computing alignments...  [38.303s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.143s]
Computing alignments...  [38.327s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.452s]
Computing alignments...  [38.485s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.463s]
Computing alignments...  [37.981s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
 [627.77s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [29.59s]
Masking reference...  [30.842s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.847s]
Allocating buffers...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.539s]
Building query seed array...  [2.595s]
Computing hash join...  [5.226s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [88.188s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.524s]
Building query seed array...  [2.908s]
Computing hash join...  [5.341s]
Masking low complexity seeds...  [0.245s]
Searching alignments...  [57.373s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.419s]
Building query seed array...  [3.114s]
Computing hash join...  [5.231s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [49.488s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.97s]
Building query seed array...  [2.486s]
Computing hash join...  [5.164s]
Masking low complexity seeds...  [0.236s]
Searching alignments...  [44.78s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.225s]
Building query seed array...  [2.337s]
Computing hash join...  [5.015s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [44.585s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.047s]
Building query seed array...  [2.611s]
Computing hash join...  [5.07s]
Masking low complexity seeds...  [0.23s]
Searching alignments...  [35.948s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.496s]
Building query seed array...  [2.731s]
Computing hash join...  [4.983s]
Masking low complexity seeds...  [0.227s]
Searching alignments...  [38.941s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.72s]
Building query seed array...  [2.327s]
Computing hash join...  [5.047s]
Masking low complexity seeds...  [0.235s]
Searching alignments...  [34.781s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.159s]
Clearing query masking...  [2.075s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [7.755s]
Sorting trace points...  [1.503s]
Computing alignments...  [36.486s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.095s]
Sorting trace points...  [1.345s]
Computing alignments...  [36.896s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.439s]
Computing alignments...  [36.704s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.42s]
Computing alignments...  [36.469s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.352s]
Computing alignments...  [36.677s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.392s]
Computing alignments...  [36.82s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.141s]
Computing alignments...  [36.382s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.038s]
Sorting trace points...  [1.056s]
Computing alignments...  [36.65s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.444s]
Computing alignments...  [37.112s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.085s]
Computing alignments...  [38.481s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.487s]
Computing alignments...  [38.45s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.449s]
Computing alignments...  [38.667s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.143s]
Computing alignments...  [38.514s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.329s]
Computing alignments...  [38.605s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.462s]
Computing alignments...  [38.652s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.492s]
Computing alignments...  [38.255s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [630.166s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.606s]
Masking reference...  [30.85s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.493s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.741s]
Building query seed array...  [2.488s]
Computing hash join...  [5.342s]
Masking low complexity seeds...  [0.246s]
Searching alignments...  [88.267s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.493s]
Building query seed array...  [2.917s]
Computing hash join...  [5.316s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [56.935s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.666s]
Building query seed array...  [3.099s]
Computing hash join...  [5.189s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [52.462s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.827s]
Building query seed array...  [2.5s]
Computing hash join...  [5.334s]
Masking low complexity seeds...  [0.242s]
Searching alignments...  [45.722s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.78s]
Building query seed array...  [2.277s]
Computing hash join...  [5.09s]
Masking low complexity seeds...  [0.232s]
Searching alignments...  [45.792s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.171s]
Building query seed array...  [2.638s]
Computing hash join...  [5.094s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [37.001s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.21s]
Building query seed array...  [2.776s]
Computing hash join...  [4.996s]
Masking low complexity seeds...  [0.226s]
Searching alignments...  [38.878s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.771s]
Building query seed array...  [2.203s]
Computing hash join...  [4.909s]
Masking low complexity seeds...  [0.233s]
Searching alignments...  [34.177s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.142s]
Clearing query masking...  [1.939s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.107s]
Sorting trace points...  [1.478s]
Computing alignments...  [36.478s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.314s]
Sorting trace points...  [1.718s]
Computing alignments...  [36.931s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.085s]
Sorting trace points...  [1.228s]
Computing alignments...  [36.741s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.385s]
Computing alignments...  [36.431s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.114s]
Sorting trace points...  [1.375s]
Computing alignments...  [36.679s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.386s]
Computing alignments...  [36.929s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.372s]
Computing alignments...  [36.506s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.416s]
Computing alignments...  [36.654s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.365s]
Computing alignments...  [37.114s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.132s]
Computing alignments...  [38.575s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.43s]
Computing alignments...  [38.436s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.089s]
Computing alignments...  [38.574s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.197s]
Computing alignments...  [38.461s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.243s]
Computing alignments...  [38.541s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.36s]
Computing alignments...  [38.615s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.408s]
Computing alignments...  [38.256s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [630.129s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [26.786s]
Masking reference...  [25.638s]
Initializing dictionary...  [0.063s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [26.467s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.429s]
Building query seed array...  [2.655s]
Computing hash join...  [4.423s]
Masking low complexity seeds...  [0.241s]
Searching alignments...  [71.743s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [10.103s]
Building query seed array...  [2.915s]
Computing hash join...  [4.38s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [47.07s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [11.121s]
Building query seed array...  [3.203s]
Computing hash join...  [4.388s]
Masking low complexity seeds...  [0.228s]
Searching alignments...  [41.497s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [8.061s]
Building query seed array...  [2.52s]
Computing hash join...  [4.387s]
Masking low complexity seeds...  [0.231s]
Searching alignments...  [36.982s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [8.326s]
Building query seed array...  [2.255s]
Computing hash join...  [4.159s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [37.344s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [10.126s]
Building query seed array...  [2.741s]
Computing hash join...  [4.191s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [30.461s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [11.277s]
Building query seed array...  [2.823s]
Computing hash join...  [4.249s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [32.187s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [8.437s]
Building query seed array...  [2.33s]
Computing hash join...  [4.233s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [28.007s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.107s]
Clearing query masking...  [1.955s]
Opening temporary output file...  [0.028s]
Computing alignments... Loading trace points...  [6.042s]
Sorting trace points...  [1.222s]
Computing alignments...  [29.159s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.058s]
Sorting trace points...  [0.867s]
Computing alignments...  [29.488s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.048s]
Sorting trace points...  [0.865s]
Computing alignments...  [29.309s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.065s]
Sorting trace points...  [0.859s]
Computing alignments...  [29.23s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.107s]
Computing alignments...  [29.362s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.158s]
Computing alignments...  [29.479s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.15s]
Computing alignments...  [29.058s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.018s]
Computing alignments...  [29.213s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.119s]
Computing alignments...  [29.554s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.204s]
Computing alignments...  [30.724s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.144s]
Computing alignments...  [30.568s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.156s]
Computing alignments...  [30.79s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.087s]
Sorting trace points...  [1.159s]
Computing alignments...  [30.655s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.175s]
Computing alignments...  [30.714s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.057s]
Sorting trace points...  [0.927s]
Computing alignments...  [30.883s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.054s]
Computing alignments...  [30.367s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [502.936s]
Deallocating reference...  [0.048s]
Loading reference sequences...  [0.085s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [2258.51s]
 [2258.51s]
Deallocating queries...  [0.068s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [3.79s]
 [5.071s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 20077.2s
Reported 2917659988 pairwise alignments, 2917659988 HSPs.
16565353 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E16_R1.fastp-trim.20230215.fq.gz complete: E16_R1.blastx.meganized.daa

Now MEGANizing E16_R1.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: E16_R1.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 100% (272.2s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.1s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (5,511.0s)
Total reads:       16,565,353
With hits:          16,565,353 
Alignments:      2,913,318,388
Assig. Taxonomy:    15,242,133
Assig. SEED:           116,255
Assig. EGGNOG:          51,700
Assig. GTDB:           442,232
Assig. EC:           2,678,126
Assig. INTERPRO2GO:  1,343,070
MinSupport set to: 8282
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.5s)
Min-supp. changes:       4,004
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (12.3s)
Min-supp. changes:       3,005
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (58.3s)
Binning reads Syncing
100% (0.4s)
Class. Taxonomy:            61
Class. SEED:               493
Class. EGGNOG:           1,717
Class. GTDB:                16
Class. EC:               2,323
Class. INTERPRO2GO:      7,934
Total time:  5,864s
Peak memory: 31.7 of 195.3G
MEGANization of E16_R1.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E16_R2.fastp-trim.20230215.fq.gz...
148bb20a6737d20d3ee15c02b5d2ffc4  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E16_R2.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E16_R2.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.306s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.724s]
Opening the output file...  [0s]
Loading query sequences...  [92.005s]
Masking queries...  [23.138s]
Algorithm: Double-indexed
Building query histograms...  [24.452s]
Loading reference sequences...  [29.814s]
Masking reference...  [32.122s]
Initializing dictionary...  [0.08s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.153s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.43s]
Building query seed array...  [2.555s]
Computing hash join...  [5.546s]
Masking low complexity seeds...  [0.29s]
Searching alignments...  [90.39s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.534s]
Building query seed array...  [2.931s]
Computing hash join...  [5.516s]
Masking low complexity seeds...  [0.282s]
Searching alignments...  [57.232s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.608s]
Building query seed array...  [3.064s]
Computing hash join...  [5.352s]
Masking low complexity seeds...  [0.286s]
Searching alignments...  [51.064s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.153s]
Building query seed array...  [2.472s]
Computing hash join...  [5.534s]
Masking low complexity seeds...  [0.285s]
Searching alignments...  [45.927s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.893s]
Building query seed array...  [2.335s]
Computing hash join...  [5.257s]
Masking low complexity seeds...  [0.274s]
Searching alignments...  [49.712s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.39s]
Building query seed array...  [2.61s]
Computing hash join...  [5.181s]
Masking low complexity seeds...  [0.269s]
Searching alignments...  [38.16s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.834s]
Building query seed array...  [2.737s]
Computing hash join...  [5.255s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [41.01s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.221s]
Building query seed array...  [2.264s]
Computing hash join...  [5.128s]
Masking low complexity seeds...  [0.27s]
Searching alignments...  [35.299s]
Deallocating memory...  [0s]
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Clearing query masking...  [1.974s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.248s]
Sorting trace points...  [1.492s]
Computing alignments...  [36.731s]
Deallocating buffers...  [0.019s]
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Computing alignments...  [36.788s]
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Computing alignments...  [36.821s]
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Computing alignments...  [36.333s]
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Computing alignments...  [36.321s]
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Computing alignments...  [37.254s]
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Computing alignments...  [39.492s]
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Computing alignments...  [39.316s]
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Computing alignments...  [39.48s]
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Computing alignments...  [39.294s]
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Computing alignments...  [39.517s]
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Computing alignments...  [39.691s]
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Computing alignments...  [39.124s]
Deallocating buffers...  [0.017s]
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Deallocating reference...  [0.061s]
Loading reference sequences...  [36.788s]
Masking reference...  [32.183s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.835s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.029s]
Building query seed array...  [2.553s]
Computing hash join...  [5.479s]
Masking low complexity seeds...  [0.281s]
Searching alignments...  [86.292s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.26s]
Building query seed array...  [3.005s]
Computing hash join...  [5.386s]
Masking low complexity seeds...  [0.294s]
Searching alignments...  [56.144s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [14.021s]
Building query seed array...  [3.084s]
Computing hash join...  [5.371s]
Masking low complexity seeds...  [0.269s]
Searching alignments...  [50.776s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.11s]
Building query seed array...  [2.519s]
Computing hash join...  [5.46s]
Masking low complexity seeds...  [0.279s]
Searching alignments...  [44.547s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.306s]
Building query seed array...  [2.277s]
Computing hash join...  [5.173s]
Masking low complexity seeds...  [0.266s]
Searching alignments...  [47.342s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.707s]
Building query seed array...  [2.615s]
Computing hash join...  [5.238s]
Masking low complexity seeds...  [0.267s]
Searching alignments...  [37.215s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.079s]
Building query seed array...  [2.756s]
Computing hash join...  [5.221s]
Masking low complexity seeds...  [0.274s]
Searching alignments...  [39.932s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.908s]
Building query seed array...  [2.358s]
Computing hash join...  [5.117s]
Masking low complexity seeds...  [0.265s]
Searching alignments...  [34.733s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.14s]
Clearing query masking...  [1.972s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.093s]
Sorting trace points...  [1.449s]
Computing alignments...  [36.423s]
Deallocating buffers...  [0.018s]
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Sorting trace points...  [1.303s]
Computing alignments...  [36.522s]
Deallocating buffers...  [0.02s]
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Computing alignments...  [36.865s]
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Computing alignments...  [36.461s]
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Computing alignments...  [36.436s]
Deallocating buffers...  [0.02s]
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Computing alignments...  [36.797s]
Deallocating buffers...  [0.017s]
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Computing alignments...  [36.086s]
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Computing alignments...  [36.152s]
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Computing alignments...  [37.223s]
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Computing alignments...  [39.226s]
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Computing alignments...  [39.103s]
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Computing alignments...  [39.299s]
Deallocating buffers...  [0.018s]
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Computing alignments...  [39.108s]
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Computing alignments...  [39.233s]
Deallocating buffers...  [0.017s]
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Computing alignments...  [39.393s]
Deallocating buffers...  [0.02s]
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Computing alignments...  [38.842s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
 [631.887s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [29.811s]
Masking reference...  [32.217s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.12s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.198s]
Building query seed array...  [2.533s]
Computing hash join...  [5.336s]
Masking low complexity seeds...  [0.27s]
Searching alignments...  [88.492s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.206s]
Building query seed array...  [2.962s]
Computing hash join...  [5.475s]
Masking low complexity seeds...  [0.287s]
Searching alignments...  [56.856s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.512s]
Building query seed array...  [3.073s]
Computing hash join...  [5.444s]
Masking low complexity seeds...  [0.284s]
Searching alignments...  [53.224s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.498s]
Building query seed array...  [2.516s]
Computing hash join...  [5.401s]
Masking low complexity seeds...  [0.282s]
Searching alignments...  [47.03s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.913s]
Building query seed array...  [2.275s]
Computing hash join...  [5.126s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [49.857s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.434s]
Building query seed array...  [2.578s]
Computing hash join...  [5.121s]
Masking low complexity seeds...  [0.274s]
Searching alignments...  [37.46s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.26s]
Building query seed array...  [2.813s]
Computing hash join...  [5.157s]
Masking low complexity seeds...  [0.274s]
Searching alignments...  [41.004s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.843s]
Building query seed array...  [2.343s]
Computing hash join...  [5.213s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [36.166s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.133s]
Clearing query masking...  [1.995s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [7.271s]
Sorting trace points...  [1.456s]
Computing alignments...  [36.459s]
Deallocating buffers...  [0.017s]
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Sorting trace points...  [1.379s]
Computing alignments...  [36.732s]
Deallocating buffers...  [0.016s]
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Computing alignments...  [36.708s]
Deallocating buffers...  [0.024s]
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Computing alignments...  [36.433s]
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Computing alignments...  [36.542s]
Deallocating buffers...  [0.02s]
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Computing alignments...  [36.815s]
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Sorting trace points...  [1.121s]
Computing alignments...  [36.22s]
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Computing alignments...  [36.325s]
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Computing alignments...  [37.249s]
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Computing alignments...  [39.312s]
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Computing alignments...  [39.303s]
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Sorting trace points...  [1.444s]
Computing alignments...  [39.535s]
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Computing alignments...  [39.255s]
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Computing alignments...  [39.475s]
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Computing alignments...  [39.095s]
Deallocating buffers...  [0.021s]
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 [635.444s]
Deallocating reference...  [0.063s]
Loading reference sequences...  [33.811s]
Masking reference...  [31.539s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.691s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.129s]
Building query seed array...  [2.512s]
Computing hash join...  [5.512s]
Masking low complexity seeds...  [0.277s]
Searching alignments...  [88.063s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.424s]
Building query seed array...  [2.956s]
Computing hash join...  [5.484s]
Masking low complexity seeds...  [0.284s]
Searching alignments...  [56.664s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.486s]
Building query seed array...  [3.035s]
Computing hash join...  [5.37s]
Masking low complexity seeds...  [0.287s]
Searching alignments...  [50.054s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.369s]
Building query seed array...  [2.588s]
Computing hash join...  [5.454s]
Masking low complexity seeds...  [0.284s]
Searching alignments...  [45.032s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.232s]
Building query seed array...  [2.272s]
Computing hash join...  [5.231s]
Masking low complexity seeds...  [0.273s]
Searching alignments...  [49.046s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.45s]
Building query seed array...  [2.598s]
Computing hash join...  [5.182s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [37.526s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.25s]
Building query seed array...  [2.788s]
Computing hash join...  [5.243s]
Masking low complexity seeds...  [0.267s]
Searching alignments...  [40.638s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.093s]
Building query seed array...  [2.268s]
Computing hash join...  [5.16s]
Masking low complexity seeds...  [0.27s]
Searching alignments...  [34.534s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.987s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.144s]
Sorting trace points...  [1.408s]
Computing alignments...  [36.592s]
Deallocating buffers...  [0.019s]
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Sorting trace points...  [1.358s]
Computing alignments...  [36.561s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.393s]
Computing alignments...  [36.668s]
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Loading trace points...  [0.261s]
Sorting trace points...  [1.449s]
Computing alignments...  [36.393s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.026s]
Computing alignments...  [36.548s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.438s]
Computing alignments...  [36.769s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.112s]
Sorting trace points...  [1.399s]
Computing alignments...  [36.319s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.306s]
Computing alignments...  [36.299s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.352s]
Computing alignments...  [37.261s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.033s]
Sorting trace points...  [1.562s]
Computing alignments...  [39.436s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.297s]
Sorting trace points...  [1.534s]
Computing alignments...  [39.356s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.543s]
Computing alignments...  [39.486s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.181s]
Computing alignments...  [39.363s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.491s]
Computing alignments...  [39.38s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.487s]
Computing alignments...  [39.517s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
Sorting trace points...  [1.473s]
Computing alignments...  [38.947s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
 [636.165s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [244.332s]
Masking reference...  [32.203s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.014s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.559s]
Building query seed array...  [2.499s]
Computing hash join...  [5.431s]
Masking low complexity seeds...  [0.277s]
Searching alignments...  [87.93s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.369s]
Building query seed array...  [2.933s]
Computing hash join...  [5.465s]
Masking low complexity seeds...  [0.286s]
Searching alignments...  [56.048s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.407s]
Building query seed array...  [3.134s]
Computing hash join...  [5.455s]
Masking low complexity seeds...  [0.29s]
Searching alignments...  [50.792s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.379s]
Building query seed array...  [2.509s]
Computing hash join...  [5.519s]
Masking low complexity seeds...  [0.281s]
Searching alignments...  [44.009s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.313s]
Building query seed array...  [2.261s]
Computing hash join...  [5.163s]
Masking low complexity seeds...  [0.259s]
Searching alignments...  [46.371s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.404s]
Building query seed array...  [2.712s]
Computing hash join...  [5.244s]
Masking low complexity seeds...  [0.278s]
Searching alignments...  [37.562s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.266s]
Building query seed array...  [2.851s]
Computing hash join...  [5.237s]
Masking low complexity seeds...  [0.269s]
Searching alignments...  [40.003s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.906s]
Building query seed array...  [2.36s]
Computing hash join...  [5.168s]
Masking low complexity seeds...  [0.273s]
Searching alignments...  [34.168s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.13s]
Clearing query masking...  [1.946s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.117s]
Sorting trace points...  [1.49s]
Computing alignments...  [36.378s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.374s]
Computing alignments...  [36.551s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.263s]
Computing alignments...  [36.684s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.369s]
Computing alignments...  [36.384s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.116s]
Sorting trace points...  [1.04s]
Computing alignments...  [36.5s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.26s]
Computing alignments...  [36.762s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.189s]
Computing alignments...  [36.153s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.081s]
Computing alignments...  [36.283s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.176s]
Computing alignments...  [37.27s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.131s]
Computing alignments...  [39.336s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.131s]
Computing alignments...  [39.145s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.042s]
Sorting trace points...  [1.353s]
Computing alignments...  [39.357s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.482s]
Computing alignments...  [39.111s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.197s]
Computing alignments...  [39.16s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.229s]
Computing alignments...  [39.253s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.182s]
Computing alignments...  [38.787s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
 [631.392s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [33.298s]
Masking reference...  [31.369s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.72s]
Allocating buffers...  [0.001s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.507s]
Building query seed array...  [2.429s]
Computing hash join...  [5.374s]
Masking low complexity seeds...  [0.279s]
Searching alignments...  [85.467s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.615s]
Building query seed array...  [2.888s]
Computing hash join...  [5.408s]
Masking low complexity seeds...  [0.283s]
Searching alignments...  [54.725s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.613s]
Building query seed array...  [3.2s]
Computing hash join...  [5.352s]
Masking low complexity seeds...  [0.29s]
Searching alignments...  [50.175s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.877s]
Building query seed array...  [2.44s]
Computing hash join...  [5.448s]
Masking low complexity seeds...  [0.282s]
Searching alignments...  [45.162s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.009s]
Building query seed array...  [2.257s]
Computing hash join...  [5.211s]
Masking low complexity seeds...  [0.266s]
Searching alignments...  [47.034s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.739s]
Building query seed array...  [2.658s]
Computing hash join...  [5.154s]
Masking low complexity seeds...  [0.269s]
Searching alignments...  [38.262s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.514s]
Building query seed array...  [2.836s]
Computing hash join...  [5.201s]
Masking low complexity seeds...  [0.266s]
Searching alignments...  [39.536s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.078s]
Building query seed array...  [2.294s]
Computing hash join...  [5.174s]
Masking low complexity seeds...  [0.275s]
Searching alignments...  [34.029s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.134s]
Clearing query masking...  [2.075s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [7.12s]
Sorting trace points...  [1.43s]
Computing alignments...  [36.004s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.13s]
Computing alignments...  [36.165s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.384s]
Computing alignments...  [36.261s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.311s]
Computing alignments...  [35.95s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.015s]
Computing alignments...  [36.102s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.401s]
Computing alignments...  [36.355s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.194s]
Computing alignments...  [35.999s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.093s]
Sorting trace points...  [1.409s]
Computing alignments...  [35.953s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.089s]
Computing alignments...  [36.932s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.084s]
Sorting trace points...  [1.226s]
Computing alignments...  [39.154s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.549s]
Computing alignments...  [38.962s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.245s]
Computing alignments...  [39.115s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.3s]
Computing alignments...  [38.946s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.278s]
Computing alignments...  [39.063s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.489s]
Computing alignments...  [39.181s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
Sorting trace points...  [1.082s]
Computing alignments...  [38.565s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [627.663s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.68s]
Masking reference...  [30.847s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.601s]
Allocating buffers...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.491s]
Building query seed array...  [2.531s]
Computing hash join...  [5.471s]
Masking low complexity seeds...  [0.289s]
Searching alignments...  [88.758s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.344s]
Building query seed array...  [2.955s]
Computing hash join...  [5.398s]
Masking low complexity seeds...  [0.283s]
Searching alignments...  [58.203s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.946s]
Building query seed array...  [3.126s]
Computing hash join...  [5.429s]
Masking low complexity seeds...  [0.284s]
Searching alignments...  [50.512s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.16s]
Building query seed array...  [2.507s]
Computing hash join...  [5.353s]
Masking low complexity seeds...  [0.276s]
Searching alignments...  [44.578s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.853s]
Building query seed array...  [2.325s]
Computing hash join...  [5.152s]
Masking low complexity seeds...  [0.275s]
Searching alignments...  [49.391s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.608s]
Building query seed array...  [2.623s]
Computing hash join...  [5.146s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [36.625s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.041s]
Building query seed array...  [2.772s]
Computing hash join...  [5.1s]
Masking low complexity seeds...  [0.272s]
Searching alignments...  [40.199s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.758s]
Building query seed array...  [2.332s]
Computing hash join...  [5.203s]
Masking low complexity seeds...  [0.275s]
Searching alignments...  [35.532s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.128s]
Clearing query masking...  [1.93s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.162s]
Sorting trace points...  [1.489s]
Computing alignments...  [36.315s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.373s]
Computing alignments...  [36.377s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.427s]
Computing alignments...  [36.416s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.324s]
Computing alignments...  [36.254s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.421s]
Computing alignments...  [36.291s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.402s]
Computing alignments...  [36.533s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.107s]
Computing alignments...  [35.914s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.375s]
Computing alignments...  [36.034s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.652s]
Sorting trace points...  [1.49s]
Computing alignments...  [37.153s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.538s]
Computing alignments...  [39.157s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.458s]
Computing alignments...  [39.106s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.436s]
Sorting trace points...  [1.599s]
Computing alignments...  [39.303s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.51s]
Computing alignments...  [39.143s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.487s]
Computing alignments...  [39.132s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.133s]
Computing alignments...  [39.275s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.498s]
Computing alignments...  [38.748s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
 [633.13s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [30.18s]
Masking reference...  [31.316s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [33.566s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.287s]
Building query seed array...  [2.4s]
Computing hash join...  [5.4s]
Masking low complexity seeds...  [0.275s]
Searching alignments...  [87.719s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.434s]
Building query seed array...  [2.903s]
Computing hash join...  [5.425s]
Masking low complexity seeds...  [0.289s]
Searching alignments...  [56.074s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.439s]
Building query seed array...  [3.127s]
Computing hash join...  [5.481s]
Masking low complexity seeds...  [0.279s]
Searching alignments...  [52.204s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.877s]
Building query seed array...  [2.489s]
Computing hash join...  [5.377s]
Masking low complexity seeds...  [0.283s]
Searching alignments...  [46.302s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.017s]
Building query seed array...  [2.343s]
Computing hash join...  [5.105s]
Masking low complexity seeds...  [0.27s]
Searching alignments...  [48.756s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.188s]
Building query seed array...  [2.603s]
Computing hash join...  [5.151s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [38.088s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.625s]
Building query seed array...  [2.799s]
Computing hash join...  [5.294s]
Masking low complexity seeds...  [0.267s]
Searching alignments...  [40.871s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.04s]
Building query seed array...  [2.332s]
Computing hash join...  [5.1s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [35.057s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.127s]
Clearing query masking...  [1.879s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.332s]
Sorting trace points...  [1.452s]
Computing alignments...  [36.311s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.415s]
Computing alignments...  [36.438s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.386s]
Computing alignments...  [36.446s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.395s]
Computing alignments...  [36.285s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.081s]
Computing alignments...  [36.328s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.412s]
Computing alignments...  [36.572s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.345s]
Computing alignments...  [35.948s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.187s]
Computing alignments...  [36.016s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.413s]
Computing alignments...  [37.001s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.516s]
Computing alignments...  [39.124s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.462s]
Computing alignments...  [39.155s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.535s]
Computing alignments...  [39.253s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.464s]
Computing alignments...  [39.061s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.511s]
Computing alignments...  [39.174s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.468s]
Computing alignments...  [39.273s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.099s]
Computing alignments...  [38.744s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [631.844s]
Deallocating reference...  [0.062s]
Loading reference sequences...  [29.693s]
Masking reference...  [30.84s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.781s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.358s]
Building query seed array...  [2.475s]
Computing hash join...  [5.343s]
Masking low complexity seeds...  [0.277s]
Searching alignments...  [88.971s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.388s]
Building query seed array...  [2.907s]
Computing hash join...  [5.494s]
Masking low complexity seeds...  [0.29s]
Searching alignments...  [56.773s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.52s]
Building query seed array...  [3.024s]
Computing hash join...  [5.441s]
Masking low complexity seeds...  [0.276s]
Searching alignments...  [51.2s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.934s]
Building query seed array...  [2.499s]
Computing hash join...  [5.376s]
Masking low complexity seeds...  [0.285s]
Searching alignments...  [44.257s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.266s]
Building query seed array...  [2.23s]
Computing hash join...  [5.119s]
Masking low complexity seeds...  [0.271s]
Searching alignments...  [48.101s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.807s]
Building query seed array...  [2.648s]
Computing hash join...  [5.076s]
Masking low complexity seeds...  [0.259s]
Searching alignments...  [37.58s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.574s]
Building query seed array...  [2.765s]
Computing hash join...  [5.17s]
Masking low complexity seeds...  [0.268s]
Searching alignments...  [40.426s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.882s]
Building query seed array...  [2.33s]
Computing hash join...  [5.158s]
Masking low complexity seeds...  [0.258s]
Searching alignments...  [34.68s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.137s]
Clearing query masking...  [2.008s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [7.861s]
Sorting trace points...  [1.477s]
Computing alignments...  [36.399s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.117s]
Computing alignments...  [36.488s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.423s]
Computing alignments...  [36.566s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0s]
Sorting trace points...  [1.403s]
Computing alignments...  [36.341s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.337s]
Computing alignments...  [36.328s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.4s]
Computing alignments...  [36.608s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.414s]
Computing alignments...  [35.98s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.369s]
Computing alignments...  [36.118s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.039s]
Sorting trace points...  [1.398s]
Computing alignments...  [37.025s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.179s]
Computing alignments...  [39.142s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.519s]
Computing alignments...  [39.047s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.042s]
Sorting trace points...  [1.516s]
Computing alignments...  [39.34s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.333s]
Computing alignments...  [39.15s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.485s]
Computing alignments...  [39.151s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.182s]
Computing alignments...  [39.246s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.186s]
Computing alignments...  [38.895s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [632.623s]
Deallocating reference...  [0.057s]
Loading reference sequences...  [29.536s]
Masking reference...  [32.049s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.142s]
Allocating buffers...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.325s]
Building query seed array...  [2.442s]
Computing hash join...  [5.423s]
Masking low complexity seeds...  [0.284s]
Searching alignments...  [89.653s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.507s]
Building query seed array...  [2.948s]
Computing hash join...  [5.522s]
Masking low complexity seeds...  [0.283s]
Searching alignments...  [57.223s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.321s]
Building query seed array...  [3.097s]
Computing hash join...  [5.367s]
Masking low complexity seeds...  [0.28s]
Searching alignments...  [51.069s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.069s]
Building query seed array...  [2.528s]
Computing hash join...  [5.336s]
Masking low complexity seeds...  [0.279s]
Searching alignments...  [44.994s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.175s]
Building query seed array...  [2.266s]
Computing hash join...  [5.106s]
Masking low complexity seeds...  [0.264s]
Searching alignments...  [48.22s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.976s]
Building query seed array...  [2.646s]
Computing hash join...  [5.218s]
Masking low complexity seeds...  [0.269s]
Searching alignments...  [36.997s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.157s]
Building query seed array...  [2.79s]
Computing hash join...  [5.117s]
Masking low complexity seeds...  [0.262s]
Searching alignments...  [40.409s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.99s]
Building query seed array...  [2.221s]
Computing hash join...  [5.147s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [36.361s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.129s]
Clearing query masking...  [1.98s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.052s]
Sorting trace points...  [1.504s]
Computing alignments...  [36.214s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.069s]
Computing alignments...  [36.332s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.04s]
Sorting trace points...  [1.399s]
Computing alignments...  [36.354s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.358s]
Computing alignments...  [36.118s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.105s]
Computing alignments...  [36.231s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.415s]
Computing alignments...  [36.546s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.334s]
Computing alignments...  [35.926s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.277s]
Computing alignments...  [36.049s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.407s]
Computing alignments...  [36.935s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.138s]
Computing alignments...  [39.162s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.507s]
Computing alignments...  [39.107s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.23s]
Computing alignments...  [39.192s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.336s]
Computing alignments...  [39.048s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.099s]
Sorting trace points...  [1.387s]
Computing alignments...  [39.234s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.543s]
Computing alignments...  [39.303s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.482s]
Computing alignments...  [38.774s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
 [630.257s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [33.522s]
Masking reference...  [30.832s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.476s]
Allocating buffers...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.146s]
Building query seed array...  [2.542s]
Computing hash join...  [5.39s]
Masking low complexity seeds...  [0.285s]
Searching alignments...  [87.829s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.675s]
Building query seed array...  [2.916s]
Computing hash join...  [5.423s]
Masking low complexity seeds...  [0.292s]
Searching alignments...  [55.623s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.128s]
Building query seed array...  [3.022s]
Computing hash join...  [5.422s]
Masking low complexity seeds...  [0.279s]
Searching alignments...  [51.165s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.267s]
Building query seed array...  [2.5s]
Computing hash join...  [5.357s]
Masking low complexity seeds...  [0.289s]
Searching alignments...  [44.081s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.045s]
Building query seed array...  [2.2s]
Computing hash join...  [5.203s]
Masking low complexity seeds...  [0.275s]
Searching alignments...  [47.042s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.753s]
Building query seed array...  [2.622s]
Computing hash join...  [5.127s]
Masking low complexity seeds...  [0.267s]
Searching alignments...  [37.81s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.391s]
Building query seed array...  [2.787s]
Computing hash join...  [5.213s]
Masking low complexity seeds...  [0.276s]
Searching alignments...  [39.644s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.058s]
Building query seed array...  [2.203s]
Computing hash join...  [5.173s]
Masking low complexity seeds...  [0.27s]
Searching alignments...  [33.763s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.133s]
Clearing query masking...  [1.961s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [7.145s]
Sorting trace points...  [1.541s]
Computing alignments...  [36.08s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.055s]
Computing alignments...  [36.22s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.41s]
Computing alignments...  [36.389s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.393s]
Computing alignments...  [35.986s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.095s]
Sorting trace points...  [1.384s]
Computing alignments...  [36.137s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.628s]
Sorting trace points...  [1.366s]
Computing alignments...  [36.353s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.327s]
Computing alignments...  [35.78s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.426s]
Computing alignments...  [35.996s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.12s]
Computing alignments...  [36.806s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.192s]
Computing alignments...  [38.973s]
Deallocating buffers...  [0.026s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.57s]
Computing alignments...  [38.847s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.172s]
Computing alignments...  [39.125s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.571s]
Computing alignments...  [38.793s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.147s]
Computing alignments...  [39.045s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.477s]
Computing alignments...  [39.02s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [1.153s]
Computing alignments...  [38.654s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
 [628.368s]
Deallocating reference...  [0.063s]
Loading reference sequences...  [243.025s]
Masking reference...  [31.048s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.675s]
Allocating buffers...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.186s]
Building query seed array...  [2.551s]
Computing hash join...  [5.489s]
Masking low complexity seeds...  [0.287s]
Searching alignments...  [87.758s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.249s]
Building query seed array...  [2.967s]
Computing hash join...  [5.442s]
Masking low complexity seeds...  [0.278s]
Searching alignments...  [56.951s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.319s]
Building query seed array...  [3.119s]
Computing hash join...  [5.359s]
Masking low complexity seeds...  [0.284s]
Searching alignments...  [51.554s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.394s]
Building query seed array...  [2.551s]
Computing hash join...  [5.388s]
Masking low complexity seeds...  [0.279s]
Searching alignments...  [46.401s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.932s]
Building query seed array...  [2.345s]
Computing hash join...  [5.2s]
Masking low complexity seeds...  [0.27s]
Searching alignments...  [49.551s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.366s]
Building query seed array...  [2.693s]
Computing hash join...  [5.271s]
Masking low complexity seeds...  [0.27s]
Searching alignments...  [37.541s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.088s]
Building query seed array...  [2.795s]
Computing hash join...  [5.208s]
Masking low complexity seeds...  [0.269s]
Searching alignments...  [40.523s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.712s]
Building query seed array...  [2.237s]
Computing hash join...  [5.173s]
Masking low complexity seeds...  [0.265s]
Searching alignments...  [34.809s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.165s]
Clearing query masking...  [2.02s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [7.938s]
Sorting trace points...  [1.489s]
Computing alignments...  [36.204s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.428s]
Computing alignments...  [36.358s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.211s]
Computing alignments...  [36.415s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.409s]
Computing alignments...  [36.203s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.116s]
Computing alignments...  [36.248s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.393s]
Computing alignments...  [36.539s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.261s]
Computing alignments...  [35.949s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.355s]
Computing alignments...  [36.067s]
Deallocating buffers...  [0.027s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.442s]
Computing alignments...  [37.052s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.502s]
Computing alignments...  [39.099s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.512s]
Computing alignments...  [39.029s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.195s]
Computing alignments...  [39.209s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.361s]
Computing alignments...  [39.151s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.446s]
Computing alignments...  [39.162s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.042s]
Sorting trace points...  [1.544s]
Computing alignments...  [39.246s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.493s]
Computing alignments...  [38.808s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
 [632.04s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [30.907s]
Masking reference...  [30.839s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [32.934s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.106s]
Building query seed array...  [2.512s]
Computing hash join...  [5.449s]
Masking low complexity seeds...  [0.28s]
Searching alignments...  [87.879s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.53s]
Building query seed array...  [2.947s]
Computing hash join...  [5.485s]
Masking low complexity seeds...  [1.153s]
Searching alignments...  [56.394s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.392s]
Building query seed array...  [3.099s]
Computing hash join...  [5.489s]
Masking low complexity seeds...  [0.284s]
Searching alignments...  [52.166s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.143s]
Building query seed array...  [2.501s]
Computing hash join...  [5.523s]
Masking low complexity seeds...  [0.289s]
Searching alignments...  [45.614s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.108s]
Building query seed array...  [2.434s]
Computing hash join...  [5.181s]
Masking low complexity seeds...  [0.274s]
Searching alignments...  [49.622s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.379s]
Building query seed array...  [2.611s]
Computing hash join...  [5.061s]
Masking low complexity seeds...  [0.261s]
Searching alignments...  [38.092s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.317s]
Building query seed array...  [2.779s]
Computing hash join...  [5.112s]
Masking low complexity seeds...  [0.265s]
Searching alignments...  [41.097s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.079s]
Building query seed array...  [2.237s]
Computing hash join...  [5.064s]
Masking low complexity seeds...  [0.26s]
Searching alignments...  [33.976s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.13s]
Clearing query masking...  [1.986s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [7.508s]
Sorting trace points...  [1.467s]
Computing alignments...  [36.11s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.395s]
Computing alignments...  [36.235s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.002s]
Sorting trace points...  [1.335s]
Computing alignments...  [36.369s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.099s]
Sorting trace points...  [1.257s]
Computing alignments...  [36.184s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.387s]
Computing alignments...  [36.262s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.412s]
Computing alignments...  [36.686s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.052s]
Sorting trace points...  [1.416s]
Computing alignments...  [35.844s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.235s]
Computing alignments...  [35.972s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.405s]
Computing alignments...  [36.933s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.495s]
Computing alignments...  [39.112s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.543s]
Computing alignments...  [39.074s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.124s]
Computing alignments...  [39.293s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.362s]
Computing alignments...  [39.201s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.193s]
Computing alignments...  [39.07s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.578s]
Computing alignments...  [39.179s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.131s]
Computing alignments...  [38.748s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
 [630.69s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [24.185s]
Masking reference...  [24.966s]
Initializing dictionary...  [0.063s]
Initializing temporary storage...  [0.007s]
Building reference histograms...  [26.912s]
Allocating buffers...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.35s]
Building query seed array...  [2.559s]
Computing hash join...  [4.537s]
Masking low complexity seeds...  [0.27s]
Searching alignments...  [71.412s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [10.197s]
Building query seed array...  [2.956s]
Computing hash join...  [4.544s]
Masking low complexity seeds...  [0.27s]
Searching alignments...  [47.063s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [11.117s]
Building query seed array...  [3.089s]
Computing hash join...  [4.491s]
Masking low complexity seeds...  [0.267s]
Searching alignments...  [42.346s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [8.32s]
Building query seed array...  [2.508s]
Computing hash join...  [4.529s]
Masking low complexity seeds...  [0.27s]
Searching alignments...  [36.861s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [8.224s]
Building query seed array...  [2.239s]
Computing hash join...  [4.265s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [38.514s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [10.452s]
Building query seed array...  [2.596s]
Computing hash join...  [4.32s]
Masking low complexity seeds...  [0.255s]
Searching alignments...  [31.852s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [10.639s]
Building query seed array...  [2.831s]
Computing hash join...  [4.344s]
Masking low complexity seeds...  [0.253s]
Searching alignments...  [32.651s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [8.185s]
Building query seed array...  [2.252s]
Computing hash join...  [4.293s]
Masking low complexity seeds...  [0.265s]
Searching alignments...  [28.4s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.111s]
Clearing query masking...  [1.892s]
Opening temporary output file...  [0.014s]
Computing alignments... Loading trace points...  [5.948s]
Sorting trace points...  [1.196s]
Computing alignments...  [28.907s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.104s]
Computing alignments...  [29.011s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.055s]
Computing alignments...  [29.042s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.115s]
Computing alignments...  [28.818s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.115s]
Computing alignments...  [28.887s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.05s]
Sorting trace points...  [0.993s]
Computing alignments...  [29.081s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.053s]
Computing alignments...  [28.591s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.136s]
Computing alignments...  [28.664s]
Deallocating buffers...  [0.013s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.108s]
Computing alignments...  [29.506s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.257s]
Computing alignments...  [31.163s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.9s]
Sorting trace points...  [1.067s]
Computing alignments...  [31.144s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.062s]
Computing alignments...  [31.257s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.198s]
Computing alignments...  [31.103s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.161s]
Computing alignments...  [31.323s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.24s]
Computing alignments...  [31.194s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
Sorting trace points...  [1.183s]
Computing alignments...  [30.809s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0s]
 [504.503s]
Deallocating reference...  [0.048s]
Loading reference sequences...  [0.117s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [2252.12s]
 [2252.12s]
Deallocating queries...  [0.058s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [3.892s]
 [5.196s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 20650.5s
Reported 2846645894 pairwise alignments, 2846645894 HSPs.
16971832 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E16_R2.fastp-trim.20230215.fq.gz complete: E16_R2.blastx.meganized.daa

Now MEGANizing E16_R2.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: E16_R2.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 100% (282.0s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.3s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (5,342.5s)
Total reads:       16,971,832
With hits:          16,971,832 
Alignments:      2,842,395,254
Assig. Taxonomy:    15,583,482
Assig. SEED:           112,953
Assig. EGGNOG:          51,020
Assig. GTDB:           431,690
Assig. EC:           2,729,689
Assig. INTERPRO2GO:  1,341,228
MinSupport set to: 8485
Binning reads Applying min-support & disabled filter to Taxonomy...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (0.3s)
Min-supp. changes:       4,120
Binning reads Applying min-support & disabled filter to GTDB...
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (11.1s)
Min-supp. changes:       3,228
Binning reads Writing classification tables
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (56.7s)
Binning reads Syncing
100% (0.3s)
Class. Taxonomy:            67
Class. SEED:               497
Class. EGGNOG:           1,727
Class. GTDB:                15
Class. EC:               2,311
Class. INTERPRO2GO:      7,973
Total time:  5,703s
Peak memory: 29.1 of 195.3G
MEGANization of E16_R2.blastx.meganized.daa completed.


Generating MD5 checksum for /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E1_R1.fastp-trim.20230215.fq.gz...
961470362e124996b63bef1bc48a8a6c  /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E1_R1.fastp-trim.20230215.fq.gz

Running DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E1_R1.fastp-trim.20230215.fq.gz.

diamond v2.1.1.155 (C) Max Planck Society for the Advancement of Science
Documentation, support and updates available at http://www.diamondsearch.org
Please cite: http://dx.doi.org/10.1038/s41592-021-01101-x Nature Methods (2021)

#CPU threads: 40
Scoring parameters: (Matrix=BLOSUM62 Lambda=0.267 K=0.041 Penalties=11/1)
Temporary directory: 
Percentage range of top alignment score to report hits: 5
Opening the database...  [0.371s]
Database: /gscratch/srlab/blastdbs/20230215-ncbi-nr/20230215-ncbi-nr.dmnd (type: Diamond database, sequences: 526308523, letters: 207134680681)
Block size = 15000000000
Opening the input file...  [0.735s]
Opening the output file...  [0s]
Loading query sequences...  [76.895s]
Masking queries...  [19.646s]
Algorithm: Double-indexed
Building query histograms...  [19.181s]
Loading reference sequences...  [29.406s]
Masking reference...  [31.982s]
Initializing dictionary...  [0.948s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.863s]
Allocating buffers...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.365s]
Building query seed array...  [2.156s]
Computing hash join...  [5.172s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [87.789s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.491s]
Building query seed array...  [2.523s]
Computing hash join...  [5.165s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [60.81s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.536s]
Building query seed array...  [2.637s]
Computing hash join...  [5.189s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [46.486s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.198s]
Building query seed array...  [2.122s]
Computing hash join...  [5.097s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [40.275s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.913s]
Building query seed array...  [1.918s]
Computing hash join...  [4.929s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [44.473s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.935s]
Building query seed array...  [2.195s]
Computing hash join...  [4.989s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [33.386s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.365s]
Building query seed array...  [2.338s]
Computing hash join...  [4.918s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [38.079s]
Deallocating memory...  [0s]
Processing query block 1, reference block 1/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.204s]
Building query seed array...  [1.964s]
Computing hash join...  [4.933s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [32.476s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.675s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.473s]
Sorting trace points...  [1.332s]
Computing alignments...  [31.858s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.133s]
Computing alignments...  [31.512s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.122s]
Computing alignments...  [31.846s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.087s]
Sorting trace points...  [1.198s]
Computing alignments...  [31.533s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.197s]
Computing alignments...  [31.163s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.225s]
Computing alignments...  [31.475s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.071s]
Computing alignments...  [31.702s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.092s]
Sorting trace points...  [1.075s]
Computing alignments...  [31.446s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.329s]
Sorting trace points...  [1.163s]
Computing alignments...  [32.478s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.045s]
Sorting trace points...  [1.257s]
Computing alignments...  [33.139s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.042s]
Sorting trace points...  [1.081s]
Computing alignments...  [33.164s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.163s]
Computing alignments...  [33.232s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.053s]
Sorting trace points...  [1.303s]
Computing alignments...  [33.302s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.292s]
Computing alignments...  [33.306s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.061s]
Sorting trace points...  [0.983s]
Computing alignments...  [33.342s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [0.979s]
Computing alignments...  [33.114s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
 [544.249s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [31.551s]
Masking reference...  [30.942s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.14s]
Allocating buffers...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.303s]
Building query seed array...  [2.183s]
Computing hash join...  [5.132s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [85.945s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.995s]
Building query seed array...  [2.496s]
Computing hash join...  [5.225s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [58.447s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.606s]
Building query seed array...  [2.587s]
Computing hash join...  [5.088s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [46.748s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.066s]
Building query seed array...  [2.148s]
Computing hash join...  [5.099s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [40.191s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.82s]
Building query seed array...  [1.972s]
Computing hash join...  [4.816s]
Masking low complexity seeds...  [0.196s]
Searching alignments...  [43.324s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.694s]
Building query seed array...  [2.195s]
Computing hash join...  [4.879s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [33.655s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.373s]
Building query seed array...  [2.347s]
Computing hash join...  [4.993s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [37.015s]
Deallocating memory...  [0s]
Processing query block 1, reference block 2/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.015s]
Building query seed array...  [1.96s]
Computing hash join...  [4.949s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [31.909s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.134s]
Clearing query masking...  [1.665s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.553s]
Sorting trace points...  [1.218s]
Computing alignments...  [31.678s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.212s]
Computing alignments...  [31.314s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.044s]
Sorting trace points...  [0.946s]
Computing alignments...  [31.693s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.037s]
Computing alignments...  [31.312s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.059s]
Sorting trace points...  [1.198s]
Computing alignments...  [31.026s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.182s]
Computing alignments...  [31.3s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.184s]
Computing alignments...  [31.523s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.09s]
Sorting trace points...  [0.992s]
Computing alignments...  [31.274s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.256s]
Computing alignments...  [32.199s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.287s]
Computing alignments...  [32.932s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [0.961s]
Computing alignments...  [33.034s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.093s]
Sorting trace points...  [1.278s]
Computing alignments...  [33.086s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.275s]
Computing alignments...  [33.684s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.076s]
Sorting trace points...  [1.299s]
Computing alignments...  [33.129s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.228s]
Computing alignments...  [33.161s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.293s]
Computing alignments...  [32.927s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [541.948s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.458s]
Masking reference...  [30.942s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.416s]
Allocating buffers...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.098s]
Building query seed array...  [2.168s]
Computing hash join...  [5.188s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [88.544s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.174s]
Building query seed array...  [2.483s]
Computing hash join...  [5.218s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [61.178s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.508s]
Building query seed array...  [2.563s]
Computing hash join...  [5.033s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [46.649s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.083s]
Building query seed array...  [2.125s]
Computing hash join...  [5.048s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [40.32s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.361s]
Building query seed array...  [1.907s]
Computing hash join...  [4.902s]
Masking low complexity seeds...  [0.199s]
Searching alignments...  [44.115s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.625s]
Building query seed array...  [2.205s]
Computing hash join...  [4.873s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [33.679s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.17s]
Building query seed array...  [2.373s]
Computing hash join...  [4.884s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [38.058s]
Deallocating memory...  [0s]
Processing query block 1, reference block 3/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.009s]
Building query seed array...  [1.973s]
Computing hash join...  [4.954s]
Masking low complexity seeds...  [0.208s]
Searching alignments...  [32.445s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.125s]
Clearing query masking...  [1.573s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.599s]
Sorting trace points...  [1.236s]
Computing alignments...  [31.723s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.038s]
Sorting trace points...  [1.239s]
Computing alignments...  [31.356s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.253s]
Computing alignments...  [31.76s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.069s]
Sorting trace points...  [0.93s]
Computing alignments...  [31.49s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.057s]
Sorting trace points...  [0.992s]
Computing alignments...  [31.109s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.059s]
Sorting trace points...  [0.887s]
Computing alignments...  [31.423s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.433s]
Sorting trace points...  [1.234s]
Computing alignments...  [31.608s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.11s]
Sorting trace points...  [0.919s]
Computing alignments...  [31.401s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.142s]
Computing alignments...  [32.359s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.281s]
Computing alignments...  [32.951s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.089s]
Computing alignments...  [33.024s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.124s]
Computing alignments...  [33.198s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.296s]
Computing alignments...  [33.273s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.083s]
Sorting trace points...  [1.248s]
Computing alignments...  [33.209s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.053s]
Sorting trace points...  [0.974s]
Computing alignments...  [33.161s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
Sorting trace points...  [1.288s]
Computing alignments...  [32.817s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
 [542.294s]
Deallocating reference...  [0.057s]
Loading reference sequences...  [29.445s]
Masking reference...  [31.385s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.872s]
Allocating buffers...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.359s]
Building query seed array...  [2.164s]
Computing hash join...  [5.144s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [86.377s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.495s]
Building query seed array...  [2.505s]
Computing hash join...  [5.179s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [59.927s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.283s]
Building query seed array...  [2.647s]
Computing hash join...  [5.034s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [47.065s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.638s]
Building query seed array...  [2.148s]
Computing hash join...  [5.2s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [41.66s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.907s]
Building query seed array...  [1.988s]
Computing hash join...  [4.876s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [42.963s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.246s]
Building query seed array...  [2.194s]
Computing hash join...  [4.916s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [34.579s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.183s]
Building query seed array...  [2.372s]
Computing hash join...  [4.893s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [38.556s]
Deallocating memory...  [0s]
Processing query block 1, reference block 4/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.126s]
Building query seed array...  [1.916s]
Computing hash join...  [4.949s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [31.902s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.133s]
Clearing query masking...  [1.627s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.409s]
Sorting trace points...  [1.276s]
Computing alignments...  [31.751s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.041s]
Sorting trace points...  [1.221s]
Computing alignments...  [31.369s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.208s]
Computing alignments...  [31.758s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.189s]
Computing alignments...  [31.391s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.18s]
Computing alignments...  [30.944s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.238s]
Sorting trace points...  [0.918s]
Computing alignments...  [31.266s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.077s]
Sorting trace points...  [0.934s]
Computing alignments...  [31.536s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.078s]
Sorting trace points...  [0.999s]
Computing alignments...  [31.245s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.22s]
Computing alignments...  [32.291s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.115s]
Computing alignments...  [33.025s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.33s]
Computing alignments...  [33.131s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.309s]
Computing alignments...  [33.155s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.037s]
Computing alignments...  [33.152s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.258s]
Computing alignments...  [33.072s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.283s]
Computing alignments...  [33.222s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.291s]
Computing alignments...  [32.914s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
 [541.817s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.246s]
Masking reference...  [30.856s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.563s]
Allocating buffers...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.35s]
Building query seed array...  [2.154s]
Computing hash join...  [5.127s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [85.733s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.464s]
Building query seed array...  [2.497s]
Computing hash join...  [5.089s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [59.302s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.549s]
Building query seed array...  [2.596s]
Computing hash join...  [5.096s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [45.776s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.786s]
Building query seed array...  [2.054s]
Computing hash join...  [5.153s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [39.277s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.159s]
Building query seed array...  [1.892s]
Computing hash join...  [4.956s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [42.478s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.51s]
Building query seed array...  [2.204s]
Computing hash join...  [4.934s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [32.812s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.045s]
Building query seed array...  [2.354s]
Computing hash join...  [4.842s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [36.36s]
Deallocating memory...  [0s]
Processing query block 1, reference block 5/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.132s]
Building query seed array...  [1.934s]
Computing hash join...  [4.924s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [32.232s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.127s]
Clearing query masking...  [1.692s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.492s]
Sorting trace points...  [1.305s]
Computing alignments...  [31.524s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.217s]
Computing alignments...  [31.179s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.065s]
Computing alignments...  [31.617s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.232s]
Computing alignments...  [31.279s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.202s]
Computing alignments...  [30.894s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.001s]
Computing alignments...  [31.16s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.046s]
Sorting trace points...  [1.212s]
Computing alignments...  [31.495s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.088s]
Sorting trace points...  [1.219s]
Computing alignments...  [31.216s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.825s]
Sorting trace points...  [1.285s]
Computing alignments...  [32.133s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.288s]
Computing alignments...  [32.885s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.002s]
Sorting trace points...  [1.308s]
Computing alignments...  [32.872s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
Sorting trace points...  [1.257s]
Computing alignments...  [32.925s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.197s]
Computing alignments...  [32.94s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.31s]
Computing alignments...  [32.943s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.266s]
Computing alignments...  [33.013s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
Sorting trace points...  [1.293s]
Computing alignments...  [32.821s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
 [540.908s]
Deallocating reference...  [0.061s]
Loading reference sequences...  [29.588s]
Masking reference...  [32.139s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.099s]
Allocating buffers...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.129s]
Building query seed array...  [2.191s]
Computing hash join...  [5.114s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [82.757s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.282s]
Building query seed array...  [2.51s]
Computing hash join...  [5.228s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [57.466s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.271s]
Building query seed array...  [2.589s]
Computing hash join...  [5.123s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [46.657s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.051s]
Building query seed array...  [2.127s]
Computing hash join...  [5.077s]
Masking low complexity seeds...  [0.221s]
Searching alignments...  [40.815s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.982s]
Building query seed array...  [1.916s]
Computing hash join...  [4.864s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [40.92s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.351s]
Building query seed array...  [2.221s]
Computing hash join...  [4.938s]
Masking low complexity seeds...  [0.205s]
Searching alignments...  [32.595s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.029s]
Building query seed array...  [2.336s]
Computing hash join...  [4.911s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [35.934s]
Deallocating memory...  [0s]
Processing query block 1, reference block 6/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.987s]
Building query seed array...  [1.96s]
Computing hash join...  [4.887s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [31.208s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.103s]
Clearing query masking...  [1.526s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.793s]
Sorting trace points...  [1.294s]
Computing alignments...  [31.588s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.135s]
Computing alignments...  [31.21s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.289s]
Sorting trace points...  [1.224s]
Computing alignments...  [31.479s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.079s]
Sorting trace points...  [1.22s]
Computing alignments...  [31.202s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.198s]
Computing alignments...  [30.75s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.213s]
Computing alignments...  [31.187s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.194s]
Computing alignments...  [31.353s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.224s]
Computing alignments...  [31.223s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.228s]
Computing alignments...  [32.074s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.217s]
Computing alignments...  [32.816s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.066s]
Sorting trace points...  [0.985s]
Computing alignments...  [32.911s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.284s]
Computing alignments...  [33.083s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.285s]
Computing alignments...  [32.963s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.068s]
Sorting trace points...  [1.316s]
Computing alignments...  [32.869s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.027s]
Computing alignments...  [32.997s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0s]
Sorting trace points...  [1.231s]
Computing alignments...  [32.704s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
 [539.99s]
Deallocating reference...  [0.063s]
Loading reference sequences...  [29.682s]
Masking reference...  [32.095s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.008s]
Building reference histograms...  [32.057s]
Allocating buffers...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.161s]
Building query seed array...  [2.121s]
Computing hash join...  [5.073s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [90.309s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.478s]
Building query seed array...  [2.465s]
Computing hash join...  [5.062s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [61.583s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.484s]
Building query seed array...  [2.578s]
Computing hash join...  [5.055s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [47.77s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.072s]
Building query seed array...  [2.114s]
Computing hash join...  [5.137s]
Masking low complexity seeds...  [0.229s]
Searching alignments...  [42.236s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.175s]
Building query seed array...  [1.913s]
Computing hash join...  [4.951s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [45.662s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.357s]
Building query seed array...  [2.245s]
Computing hash join...  [4.93s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [33.352s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.48s]
Building query seed array...  [2.37s]
Computing hash join...  [4.816s]
Masking low complexity seeds...  [0.201s]
Searching alignments...  [38.759s]
Deallocating memory...  [0s]
Processing query block 1, reference block 7/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.888s]
Building query seed array...  [2.01s]
Computing hash join...  [4.923s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [32.402s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.124s]
Clearing query masking...  [1.59s]
Opening temporary output file...  [0.001s]
Computing alignments... Loading trace points...  [6.561s]
Sorting trace points...  [1.302s]
Computing alignments...  [31.734s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.241s]
Computing alignments...  [31.336s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.178s]
Computing alignments...  [31.683s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.073s]
Sorting trace points...  [1.252s]
Computing alignments...  [31.376s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.123s]
Computing alignments...  [30.943s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.232s]
Computing alignments...  [31.306s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.197s]
Computing alignments...  [31.57s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.081s]
Sorting trace points...  [1.224s]
Computing alignments...  [31.21s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.262s]
Computing alignments...  [32.249s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.238s]
Computing alignments...  [32.962s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.051s]
Sorting trace points...  [0.983s]
Computing alignments...  [33.121s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.043s]
Sorting trace points...  [1.335s]
Computing alignments...  [33.159s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.107s]
Computing alignments...  [33.165s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.285s]
Computing alignments...  [33.046s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.286s]
Computing alignments...  [33.18s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
Sorting trace points...  [1.261s]
Computing alignments...  [32.835s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [542.191s]
Deallocating reference...  [0.063s]
Loading reference sequences...  [33.404s]
Masking reference...  [31.128s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.637s]
Allocating buffers...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [9.98s]
Building query seed array...  [2.104s]
Computing hash join...  [5.131s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [88.023s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.55s]
Building query seed array...  [2.559s]
Computing hash join...  [5.145s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [58.715s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.825s]
Building query seed array...  [2.755s]
Computing hash join...  [5.117s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [47.557s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.073s]
Building query seed array...  [2.088s]
Computing hash join...  [5.065s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [41.987s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.514s]
Building query seed array...  [1.916s]
Computing hash join...  [4.87s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [42.439s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.58s]
Building query seed array...  [2.239s]
Computing hash join...  [4.916s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [33.417s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.772s]
Building query seed array...  [2.393s]
Computing hash join...  [4.885s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [38.725s]
Deallocating memory...  [0s]
Processing query block 1, reference block 8/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.938s]
Building query seed array...  [1.901s]
Computing hash join...  [4.959s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [32.971s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.14s]
Clearing query masking...  [1.694s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.652s]
Sorting trace points...  [1.135s]
Computing alignments...  [32.148s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.236s]
Computing alignments...  [31.477s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.247s]
Computing alignments...  [31.765s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.242s]
Computing alignments...  [31.425s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.08s]
Computing alignments...  [31.055s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.073s]
Sorting trace points...  [0.912s]
Computing alignments...  [31.41s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.135s]
Computing alignments...  [31.625s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0s]
Sorting trace points...  [1.204s]
Computing alignments...  [31.334s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.08s]
Sorting trace points...  [1.245s]
Computing alignments...  [32.358s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.062s]
Sorting trace points...  [1.272s]
Computing alignments...  [33.079s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.074s]
Sorting trace points...  [1.161s]
Computing alignments...  [33.131s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.277s]
Computing alignments...  [33.183s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.158s]
Computing alignments...  [33.21s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.078s]
Sorting trace points...  [1.285s]
Computing alignments...  [33.111s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.048s]
Sorting trace points...  [1.285s]
Computing alignments...  [33.272s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0s]
Sorting trace points...  [1.255s]
Computing alignments...  [33.004s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0s]
 [543.674s]
Deallocating reference...  [0.057s]
Loading reference sequences...  [34.974s]
Masking reference...  [31.087s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.01s]
Building reference histograms...  [32.621s]
Allocating buffers...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.328s]
Building query seed array...  [2.198s]
Computing hash join...  [5.128s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [87.773s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.365s]
Building query seed array...  [2.554s]
Computing hash join...  [5.097s]
Masking low complexity seeds...  [0.223s]
Searching alignments...  [59.715s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.521s]
Building query seed array...  [2.596s]
Computing hash join...  [5.327s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [46.216s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.029s]
Building query seed array...  [2.121s]
Computing hash join...  [5.091s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [39.829s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.052s]
Building query seed array...  [1.956s]
Computing hash join...  [4.978s]
Masking low complexity seeds...  [0.211s]
Searching alignments...  [43.725s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.252s]
Building query seed array...  [2.335s]
Computing hash join...  [4.893s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [32.734s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.112s]
Building query seed array...  [2.434s]
Computing hash join...  [4.906s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [37.223s]
Deallocating memory...  [0s]
Processing query block 1, reference block 9/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.002s]
Building query seed array...  [1.979s]
Computing hash join...  [4.86s]
Masking low complexity seeds...  [0.212s]
Searching alignments...  [32.097s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.127s]
Clearing query masking...  [1.685s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.47s]
Sorting trace points...  [1.31s]
Computing alignments...  [31.99s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.072s]
Computing alignments...  [31.123s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.056s]
Sorting trace points...  [1.12s]
Computing alignments...  [31.552s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.241s]
Computing alignments...  [31.218s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.163s]
Computing alignments...  [30.844s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.199s]
Computing alignments...  [31.183s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.543s]
Sorting trace points...  [1.249s]
Computing alignments...  [31.402s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.061s]
Sorting trace points...  [1.214s]
Computing alignments...  [31.163s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.257s]
Computing alignments...  [32.095s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.304s]
Computing alignments...  [32.817s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.075s]
Sorting trace points...  [0.959s]
Computing alignments...  [32.864s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.086s]
Sorting trace points...  [1.273s]
Computing alignments...  [32.972s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.238s]
Computing alignments...  [33.008s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.289s]
Computing alignments...  [32.991s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.039s]
Sorting trace points...  [1.14s]
Computing alignments...  [33.054s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.297s]
Computing alignments...  [32.803s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
 [540.58s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [35.221s]
Masking reference...  [31.051s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.495s]
Allocating buffers...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.578s]
Building query seed array...  [2.134s]
Computing hash join...  [4.988s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [87.654s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.412s]
Building query seed array...  [2.478s]
Computing hash join...  [5.108s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [59.98s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.429s]
Building query seed array...  [2.679s]
Computing hash join...  [5.099s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [47.327s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.283s]
Building query seed array...  [2.156s]
Computing hash join...  [5.091s]
Masking low complexity seeds...  [0.22s]
Searching alignments...  [40.369s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.023s]
Building query seed array...  [1.916s]
Computing hash join...  [4.9s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [42.821s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [11.87s]
Building query seed array...  [2.242s]
Computing hash join...  [4.862s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [33.072s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.324s]
Building query seed array...  [2.311s]
Computing hash join...  [4.89s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [38.841s]
Deallocating memory...  [0s]
Processing query block 1, reference block 10/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.774s]
Building query seed array...  [1.936s]
Computing hash join...  [4.847s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [32.791s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.135s]
Clearing query masking...  [1.651s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.44s]
Sorting trace points...  [1.311s]
Computing alignments...  [31.671s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.166s]
Computing alignments...  [31.279s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.073s]
Sorting trace points...  [0.968s]
Computing alignments...  [31.779s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.863s]
Sorting trace points...  [1.075s]
Computing alignments...  [31.478s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.156s]
Computing alignments...  [30.974s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.072s]
Sorting trace points...  [0.945s]
Computing alignments...  [31.36s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.254s]
Computing alignments...  [31.584s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.206s]
Computing alignments...  [31.307s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.241s]
Computing alignments...  [32.176s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.044s]
Sorting trace points...  [1.283s]
Computing alignments...  [32.892s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.274s]
Computing alignments...  [32.963s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.148s]
Computing alignments...  [33.104s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.046s]
Sorting trace points...  [0.997s]
Computing alignments...  [33.158s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.305s]
Computing alignments...  [33.166s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.049s]
Sorting trace points...  [1.184s]
Computing alignments...  [33.195s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0s]
Sorting trace points...  [1.271s]
Computing alignments...  [32.82s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [541.962s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [29.852s]
Masking reference...  [30.849s]
Initializing dictionary...  [0.077s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.535s]
Allocating buffers...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.502s]
Building query seed array...  [2.077s]
Computing hash join...  [5.085s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [84.731s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.497s]
Building query seed array...  [2.513s]
Computing hash join...  [5.235s]
Masking low complexity seeds...  [0.218s]
Searching alignments...  [60.533s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.616s]
Building query seed array...  [2.632s]
Computing hash join...  [5.113s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [45.575s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [10.056s]
Building query seed array...  [2.124s]
Computing hash join...  [5.016s]
Masking low complexity seeds...  [0.215s]
Searching alignments...  [38.6s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.034s]
Building query seed array...  [1.888s]
Computing hash join...  [4.871s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [41.79s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.44s]
Building query seed array...  [2.253s]
Computing hash join...  [5.068s]
Masking low complexity seeds...  [0.225s]
Searching alignments...  [32.72s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [12.791s]
Building query seed array...  [2.393s]
Computing hash join...  [4.875s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [37.638s]
Deallocating memory...  [0s]
Processing query block 1, reference block 11/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.04s]
Building query seed array...  [1.931s]
Computing hash join...  [4.902s]
Masking low complexity seeds...  [0.206s]
Searching alignments...  [31.8s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.137s]
Clearing query masking...  [1.67s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.867s]
Sorting trace points...  [1.272s]
Computing alignments...  [31.366s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.072s]
Sorting trace points...  [1.094s]
Computing alignments...  [31.092s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.224s]
Computing alignments...  [31.395s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.058s]
Sorting trace points...  [1.156s]
Computing alignments...  [31.089s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.057s]
Sorting trace points...  [1.171s]
Computing alignments...  [31.367s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.077s]
Sorting trace points...  [1.192s]
Computing alignments...  [31.117s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.317s]
Sorting trace points...  [0.917s]
Computing alignments...  [31.312s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.088s]
Sorting trace points...  [1.163s]
Computing alignments...  [30.979s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.281s]
Computing alignments...  [32.034s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.069s]
Sorting trace points...  [1.21s]
Computing alignments...  [32.777s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.094s]
Sorting trace points...  [1.279s]
Computing alignments...  [32.802s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.094s]
Sorting trace points...  [1.297s]
Computing alignments...  [32.88s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.001s]
Sorting trace points...  [0.962s]
Computing alignments...  [32.952s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.223s]
Computing alignments...  [32.908s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.042s]
Sorting trace points...  [1.121s]
Computing alignments...  [32.961s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0s]
Sorting trace points...  [1.28s]
Computing alignments...  [32.669s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [538.973s]
Deallocating reference...  [0.06s]
Loading reference sequences...  [29.548s]
Masking reference...  [30.851s]
Initializing dictionary...  [0.079s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [33.26s]
Allocating buffers...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.232s]
Building query seed array...  [2.088s]
Computing hash join...  [5.007s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [86.782s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.475s]
Building query seed array...  [2.503s]
Computing hash join...  [5.018s]
Masking low complexity seeds...  [0.217s]
Searching alignments...  [60.968s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.692s]
Building query seed array...  [2.673s]
Computing hash join...  [5.108s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [47.626s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.83s]
Building query seed array...  [2.145s]
Computing hash join...  [5.039s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [41.633s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [10.204s]
Building query seed array...  [1.953s]
Computing hash join...  [4.875s]
Masking low complexity seeds...  [0.203s]
Searching alignments...  [44.731s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.319s]
Building query seed array...  [2.214s]
Computing hash join...  [4.892s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [34.132s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.665s]
Building query seed array...  [2.333s]
Computing hash join...  [4.814s]
Masking low complexity seeds...  [0.214s]
Searching alignments...  [37.239s]
Deallocating memory...  [0s]
Processing query block 1, reference block 12/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [9.912s]
Building query seed array...  [1.884s]
Computing hash join...  [4.878s]
Masking low complexity seeds...  [0.199s]
Searching alignments...  [32.007s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.123s]
Clearing query masking...  [1.646s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.461s]
Sorting trace points...  [1.259s]
Computing alignments...  [31.603s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.047s]
Sorting trace points...  [0.946s]
Computing alignments...  [31.321s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.054s]
Sorting trace points...  [1.25s]
Computing alignments...  [31.779s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.07s]
Sorting trace points...  [1.234s]
Computing alignments...  [31.38s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.059s]
Sorting trace points...  [0.897s]
Computing alignments...  [31.009s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.06s]
Sorting trace points...  [1.193s]
Computing alignments...  [31.279s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.051s]
Sorting trace points...  [1.246s]
Computing alignments...  [31.556s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.064s]
Sorting trace points...  [1.184s]
Computing alignments...  [31.198s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.105s]
Computing alignments...  [32.286s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.042s]
Sorting trace points...  [1.258s]
Computing alignments...  [32.928s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.042s]
Sorting trace points...  [0.948s]
Computing alignments...  [33.072s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.066s]
Sorting trace points...  [1.283s]
Computing alignments...  [33.116s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.294s]
Computing alignments...  [33.141s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.303s]
Computing alignments...  [33.086s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.73s]
Sorting trace points...  [1.265s]
Computing alignments...  [33.27s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
Sorting trace points...  [1.283s]
Computing alignments...  [32.896s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0s]
 [542.191s]
Deallocating reference...  [0.058s]
Loading reference sequences...  [29.529s]
Masking reference...  [30.852s]
Initializing dictionary...  [0.078s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [32.985s]
Allocating buffers...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [10.478s]
Building query seed array...  [2.26s]
Computing hash join...  [5.086s]
Masking low complexity seeds...  [0.219s]
Searching alignments...  [85.994s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [12.536s]
Building query seed array...  [2.484s]
Computing hash join...  [5.055s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [60.315s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [13.452s]
Building query seed array...  [2.596s]
Computing hash join...  [5.067s]
Masking low complexity seeds...  [0.213s]
Searching alignments...  [46.924s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [9.901s]
Building query seed array...  [2.135s]
Computing hash join...  [5.134s]
Masking low complexity seeds...  [0.222s]
Searching alignments...  [39.896s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [9.769s]
Building query seed array...  [1.916s]
Computing hash join...  [4.881s]
Masking low complexity seeds...  [0.21s]
Searching alignments...  [43.82s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [12.621s]
Building query seed array...  [2.249s]
Computing hash join...  [4.903s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [33.113s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [13.831s]
Building query seed array...  [2.304s]
Computing hash join...  [4.799s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [36.817s]
Deallocating memory...  [0s]
Processing query block 1, reference block 13/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [10.306s]
Building query seed array...  [1.953s]
Computing hash join...  [4.874s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [32.641s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.137s]
Clearing query masking...  [1.674s]
Opening temporary output file...  [0s]
Computing alignments... Loading trace points...  [6.491s]
Sorting trace points...  [1.306s]
Computing alignments...  [31.651s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.122s]
Computing alignments...  [31.263s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.065s]
Sorting trace points...  [1.153s]
Computing alignments...  [31.582s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.075s]
Sorting trace points...  [1.205s]
Computing alignments...  [31.222s]
Deallocating buffers...  [0.015s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.165s]
Computing alignments...  [30.943s]
Deallocating buffers...  [0.014s]
Loading trace points...  [0.055s]
Sorting trace points...  [1.242s]
Computing alignments...  [31.25s]
Deallocating buffers...  [0.021s]
Loading trace points...  [0.087s]
Sorting trace points...  [1.217s]
Computing alignments...  [31.446s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.067s]
Sorting trace points...  [1.174s]
Computing alignments...  [31.137s]
Deallocating buffers...  [0.02s]
Loading trace points...  [0.074s]
Sorting trace points...  [0.945s]
Computing alignments...  [32.124s]
Deallocating buffers...  [0.017s]
Loading trace points...  [0.063s]
Sorting trace points...  [1.262s]
Computing alignments...  [32.842s]
Deallocating buffers...  [0.018s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.286s]
Computing alignments...  [32.987s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0.001s]
Sorting trace points...  [1.335s]
Computing alignments...  [32.983s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.05s]
Sorting trace points...  [1.252s]
Computing alignments...  [33.047s]
Deallocating buffers...  [0.019s]
Loading trace points...  [0.071s]
Sorting trace points...  [1.265s]
Computing alignments...  [32.995s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0.047s]
Sorting trace points...  [1.249s]
Computing alignments...  [33.096s]
Deallocating buffers...  [0.022s]
Loading trace points...  [0s]
Sorting trace points...  [1.245s]
Computing alignments...  [32.834s]
Deallocating buffers...  [0.016s]
Loading trace points...  [0s]
 [540.452s]
Deallocating reference...  [0.059s]
Loading reference sequences...  [24.911s]
Masking reference...  [25.368s]
Initializing dictionary...  [0.063s]
Initializing temporary storage...  [0.009s]
Building reference histograms...  [26.586s]
Allocating buffers...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 1/4.
Building reference seed array...  [8.719s]
Building query seed array...  [2.133s]
Computing hash join...  [4.28s]
Masking low complexity seeds...  [0.207s]
Searching alignments...  [69.079s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 2/4.
Building reference seed array...  [10.312s]
Building query seed array...  [2.493s]
Computing hash join...  [4.273s]
Masking low complexity seeds...  [0.209s]
Searching alignments...  [47.03s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 3/4.
Building reference seed array...  [10.77s]
Building query seed array...  [2.651s]
Computing hash join...  [4.37s]
Masking low complexity seeds...  [0.216s]
Searching alignments...  [39.493s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 1/2, index chunk 4/4.
Building reference seed array...  [8.399s]
Building query seed array...  [2.124s]
Computing hash join...  [4.277s]
Masking low complexity seeds...  [0.204s]
Searching alignments...  [33.933s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 1/4.
Building reference seed array...  [8.06s]
Building query seed array...  [1.933s]
Computing hash join...  [4.144s]
Masking low complexity seeds...  [0.199s]
Searching alignments...  [35.497s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 2/4.
Building reference seed array...  [10.304s]
Building query seed array...  [2.309s]
Computing hash join...  [4.091s]
Masking low complexity seeds...  [0.196s]
Searching alignments...  [27.45s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 3/4.
Building reference seed array...  [10.681s]
Building query seed array...  [2.351s]
Computing hash join...  [4.067s]
Masking low complexity seeds...  [0.202s]
Searching alignments...  [30.419s]
Deallocating memory...  [0s]
Processing query block 1, reference block 14/14, shape 2/2, index chunk 4/4.
Building reference seed array...  [8.086s]
Building query seed array...  [1.89s]
Computing hash join...  [4.091s]
Masking low complexity seeds...  [0.194s]
Searching alignments...  [27.582s]
Deallocating memory...  [0s]
Deallocating buffers...  [0.107s]
Clearing query masking...  [1.595s]
Opening temporary output file...  [0.003s]
Computing alignments... Loading trace points...  [10.738s]
Sorting trace points...  [2.071s]
Computing alignments...  [49.967s]
Deallocating buffers...  [0.028s]
Loading trace points...  [0.136s]
Sorting trace points...  [2.044s]
Computing alignments...  [49.964s]
Deallocating buffers...  [0.023s]
Loading trace points...  [0.148s]
Sorting trace points...  [1.555s]
Computing alignments...  [49.439s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0.147s]
Sorting trace points...  [1.635s]
Computing alignments...  [49.838s]
Deallocating buffers...  [0.034s]
Loading trace points...  [0.184s]
Sorting trace points...  [2.169s]
Computing alignments...  [51.698s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0.158s]
Sorting trace points...  [1.717s]
Computing alignments...  [52.605s]
Deallocating buffers...  [0.038s]
Loading trace points...  [0.122s]
Sorting trace points...  [2.068s]
Computing alignments...  [53.069s]
Deallocating buffers...  [0.025s]
Loading trace points...  [0s]
Sorting trace points...  [2.137s]
Computing alignments...  [52.222s]
Deallocating buffers...  [0.024s]
Loading trace points...  [0s]
 [436.221s]
Deallocating reference...  [0.05s]
Loading reference sequences...  [0.076s]
Deallocating buffers...  [0s]
Joining output blocks... Joining output blocks...  [1904.07s]
 [1904.07s]
Deallocating queries...  [0.055s]
Loading query sequences...  [0s]
Closing the input file...  [0s]
Closing the output file... Loading dictionary...  [3.67s]
 [4.908s]
Closing the database...  [0s]
Cleaning up...  [0s]
Total time = 18198.9s
Reported 2474669643 pairwise alignments, 2474669643 HSPs.
13436671 queries aligned.
DIAMOND BLASTx on /gscratch/srlab/sam/data/P_verrucosa/RNAseq/E1_R1.fastp-trim.20230215.fq.gz complete: E1_R1.blastx.meganized.daa

Now MEGANizing E1_R1.blastx.meganized.daa
Version   MEGAN Community Edition (version 6.22.0, built 19 Feb 2022)
Author(s) Daniel H. Huson
Copyright (C) 2022 Daniel H. Huson. This program comes with ABSOLUTELY NO WARRANTY.
Java version: 17.0.2
Functional classifications to use: EC, EGGNOG, GTDB, INTERPRO2GO, SEED
Loading ncbi.map: 2,396,736
Loading ncbi.tre: 2,396,740
Loading ec.map:     8,200
Loading ec.tre:     8,204
Loading eggnog.map:    30,875
Loading eggnog.tre:    30,986
Loading gtdb.map:   240,103
Loading gtdb.tre:   240,107
Loading interpro2go.map:    14,242
Loading interpro2go.tre:    28,907
Loading seed.map:       961
Loading seed.tre:       962
Meganizing: E1_R1.blastx.meganized.daa
Meganizing init
Annotating DAA file using FAST mode (accession database and first accession per line)
Annotating references
10% 20% 30% 40% 50% 60% 70% 100% (235.4s)
Writing
10% 20% 30% 40% 50% 60% 70% 80% 90% 100% (1.2s)
Binning reads Initializing...
Initializing binning...
Using 'Naive LCA' algorithm for binning: Taxonomy
Using Best-Hit algorithm for binning: SEED
Using Best-Hit algorithm for binning: EGGNOG
Using 'Naive LCA' algorithm for binning: GTDB
Using Best-Hit algorithm for binning: EC
Using Best-Hit algorithm for binning: INTERPRO2GO
Binning reads...
Binning reads Analyzing alignments
10% 20% slurmstepd: error: *** JOB 4474442 ON n2193 CANCELLED AT 2023-03-08T15:05:10 DUE TO TIME LIMIT ***