[2020-04-26 02:02:19.872] [jointLog] [info] Fragment incompatibility prior below threshold.  Incompatible fragments will be ignored.
[2020-04-26 02:02:19.872] [jointLog] [info] Usage of --validateMappings implies use of minScoreFraction. Since not explicitly specified, it is being set to 0.65
[2020-04-26 02:02:19.872] [jointLog] [info] Usage of --validateMappings implies a default consensus slack of 0.2. Setting consensusSlack to 0.35.
[2020-04-26 02:02:19.872] [jointLog] [info] parsing read library format
[2020-04-26 02:02:19.872] [jointLog] [info] There is 1 library.
[2020-04-26 02:02:19.932] [jointLog] [info] Loading pufferfish index
[2020-04-26 02:02:19.932] [jointLog] [info] Loading dense pufferfish index.
[2020-04-26 02:02:20.158] [jointLog] [info] done
[2020-04-26 02:02:20.158] [jointLog] [info] Index contained 40,435 targets
[2020-04-26 02:02:20.173] [jointLog] [info] Number of decoys : 0
[2020-04-26 02:02:25.943] [fileLog] [info] 
At end of round 0
==================
Observed 1567896 total fragments (1567896 in most recent round)

[2020-04-26 02:02:25.943] [jointLog] [info] Computed 63,961 rich equivalence classes for further processing
[2020-04-26 02:02:25.943] [jointLog] [info] Counted 1,547,156 total reads in the equivalence classes 
[2020-04-26 02:02:25.965] [jointLog] [info] Number of mappings discarded because of alignment score : 744,608
[2020-04-26 02:02:25.965] [jointLog] [info] Number of fragments entirely discarded because of alignment score : 20,255
[2020-04-26 02:02:25.965] [jointLog] [info] Number of fragments discarded because they are best-mapped to decoys : 0
[2020-04-26 02:02:25.965] [jointLog] [info] Number of fragments discarded because they have only dovetail (discordant) mappings to valid targets : 5,061
[2020-04-26 02:02:25.969] [jointLog] [warning] Only 1547156 fragments were mapped, but the number of burn-in fragments was set to 5000000.
The effective lengths have been computed using the observed mappings.

[2020-04-26 02:02:25.969] [jointLog] [info] Mapping rate = 98.6772%

[2020-04-26 02:02:25.969] [jointLog] [info] finished quantifyLibrary()
[2020-04-26 02:02:25.970] [jointLog] [info] Starting optimizer
[2020-04-26 02:02:25.989] [jointLog] [info] Marked 0 weighted equivalence classes as degenerate
[2020-04-26 02:02:25.994] [jointLog] [info] iteration = 0 | max rel diff. = 3444.41
[2020-04-26 02:02:26.315] [jointLog] [info] iteration = 100 | max rel diff. = 1.74183
[2020-04-26 02:02:26.631] [jointLog] [info] iteration = 200 | max rel diff. = 0.123649
[2020-04-26 02:02:26.947] [jointLog] [info] iteration = 300 | max rel diff. = 0.132202
[2020-04-26 02:02:27.259] [jointLog] [info] iteration = 400 | max rel diff. = 0.0848587
[2020-04-26 02:02:27.296] [jointLog] [info] iteration = 413 | max rel diff. = 0.00990777
[2020-04-26 02:02:27.297] [jointLog] [info] Finished optimizer
[2020-04-26 02:02:27.297] [jointLog] [info] writing output